Jiaguo QI; Temirbek S.BOBUSHEV; Rashid KULMATOV; Pavel GROISMAN; Garik GUTMAN
Central Asia is one of the most vulnerable regions on the planet earth to global climate change,depending on very fragile natural resources.The Soviet legacy has left the five countries (Kazakhstan,Tajikistan,Kyrgyzstan,Turkmenistan,and Uzbekistan) with a highly integrated system but they are facing great challenges with tensions that hinder regional coordination of food and water resources.With increasing climate variability and warming trend in the region,food and water security issues become even more crucial now and,if not addressed properly,could affect the regional stability.The long-term drivers of these two most critical elements,food and water,are climate change; the immediate and probably more drastic factors affecting the food and water security are land uses driven by institutional change and economic incentives.As a feedback,changes in land use and land cover have directly implications on water uses,food production,and lifestyles of the rural community in the region.Regional and international efforts have been made to holistically understand the cause,extent,rate and societal implications of land use changes in the region.Much of these have been understood,or under investigation by various projects,but solutions or research effort to develop solutions,to these urgent regional issues are lacking.This article,serves as an introduction to the special issue,provides a brief overview of the challenges facing the Central Asian countries and various international efforts in place that resulted in the publications of this special issue.
Gebeshuber, Ille C
Biomimetic nanotechnology is a prominent research area at the meeting place of life sciences with engineering and physics: it is a continuously growing field that deals with knowledge transfer from biology to nanotechnology. Biomimetic nanotechnology is a field that has the potential to substantially support successful mastering of major global challenges. The Millennium Project was commissioned by the United Nations Secretary-General in 2002 to develop a concrete action plan for the world to reverse the grinding poverty, hunger and disease affecting billions of people. It states 15 Global Challenges: sustainable development, water, population and resources, democratization, long-term perspectives, information technology, the rich-poor gap, health, capacity to decide, peace and conflict, status of women, transnational crime, energy, science and technology and global ethics. The possible contributions to master these challenges with the help of biomimetic nanotechnology will be discussed in detail.
Tittonell, P.A.; Klerkx, L.W.A.; Baudron, F.; Félix, G.F.; Ruggia, A.P.; Apeldoorn, van D.F.; Dogliotti, S.; Mapfumo, Paul; Rossing, W.A.H.
The debate on future global food security is centered on increasing yields. This focus on availability of food is overshadowing access and utilization of food, and the stability of these over time. In addition, pleas for increasing yields across the board overlook the diversity of current positions
Our planet is dynamic; energy and matter constantly move between the hydrosphere, atmosphere and lithosphere on time scales from seconds to millenia. These tight interactions - including those between organisms and their physical environment - are what make Earth habitable. However, as Rachel Carson wrote, 'Only within the moment of time represented by the present century has one species - man - acquired significant power to alter the nature of this world'. Globalization and explosive population growth have generated far-reaching environmental problems on a scale that humanity has never faced before. Fortunately, our species has also developed an unprecedented ability to provide science-based solutions. Since processes impacting the environment involve complex biological, physical, chemical and geological interactions and feedbacks, they require the integration of expertise from all these scientific disciplines as well as input from policy makers, social scientists, and economists. This talk presents four examples of current interdisciplinary research projects conducted in my lab, each one related to a theme from one of Carson's books (Under the Sea-wind, The Sea Around Us, The Edge of the Sea, and Silent Spring). These projects, and others like them, provide hope that we can move toward a sustainable relationship with the natural world by encouraging the best scientists to conduct interdisciplinary research with direct applications for environmental management and stewardship.
Hankins, Catherine A.
ABSTRACT Six colleagues working in the HIV field were killed when their flight en route to Kuala Lumpur was shot down over the Ukraine. This report is drawn from the in memoriam keynote opening address given at the 12th International AIDS Impact conference in Amsterdam in 2015. It highlights their tangible and valued roles in the HIV response and looks forward to the road ahead. It describes the ways in which we can build on their legacy to address current global challenges in HIV prevention and treatment and to mobilise the intensified, focused resources that are needed to turn the HIV epidemic on its head. PMID:26963879
Bonet-García, Francisco; Materia, Paola; Kutsch, Werner; de Lucas, Jesús Marco; Tjulin, Anders
During the Anthropocene, mankind will face several global environmental challenges. One of the first and more successful responses provided by Science to these challenges is the collecting of long-term series of biophysical variables in order to improve our knowledge of natural systems. The huge amount of information gathered during the last decades by Research Infrastructures (RIs) has helped to understand the structure and functioning of natural systems at local and regional scales. But how can we address the global cross-scale and cross-disciplinary challenges posed by the global environment change? We believe that it will be necessary to observe, model better and understand the whole biosphere using long term data generated by international RIs. RIs play a key role on many of the last advances and discoveries in science, from the observation of the Higgs Boson at CERN to the exploration of the Universe by the telescopes of the European Southern Observatory in Chile. The scale of complexity, instrumentation, computing resources, technological advances, and also of the investments, and the size of research collaborations, do not have precedents in Science. RIs in environmental field are developing fast, but the corresponding communities need yet to further reflect the need for a wider global collaboration because the challenges to tackle are in essence of global nature. This contribution describes how COOP+ project (EU Horizon 2020 Coordination and Support Action) will promote the cooperation among RIs at a global scale to address global environmental challenges. Our project evolves from the experience of the sucessful FP7 COOPEUS project (see http://www.coopeus.eu), which explored the use and access to data from RIs in environmental research in Europe and USA. The general goal of COOP+ is to strengthen the links and coordination of the ESFRI RIs related to Marine Science (EMSO), Arctic and Atmospheric Research (EISCAT), Carbon Observation (ICOS) and Biodiversity
In the new bioeconomy, fungi play a very important role in addressing major global challenges, being instrumental for improved resource efficiency, making renewable substitutes for products from fossil resources, upgrading waste streams to valuable food and feed ingredients, counteracting life-style diseases and antibiotic resistance through strengthening the gut biota, making crop plants more robust to survive climate change conditions, and functioning as host organisms for production of new biological drugs. This range of new uses of fungi all stand on the shoulders of the efforts of mycologists over generations: the scientific discipline mycology has built comprehensive understanding within fungal biodiversity, classification, evolution, genetics, physiology, ecology, pathogenesis, and nutrition. Applied mycology could not make progress without this platform. To unfold the full potentials of what fungi can do for both environment and man we need to strengthen the field of mycology on a global scale. The current mission statement gives an overview of where we are, what needs to be done, what obstacles to overcome, and which potentials are within reach. It further provides a vision for how mycology can be strengthened: The time is right to make the world aware of the immense importance of fungi and mycology for sustainable global development, where land, water and biological materials are used in a more efficient and more sustainable manner. This is an opportunity for profiling mycology by narrating the role played by fungi in the bioeconomy. Greater awareness and appreciation of the role of fungi can be used to build support for mycology around the world. Support will attract more talent to our field of study, empower mycologists around the world to generate more funds for necessary basic research, and strengthen the global mycology network. The use of fungi for unlocking the full potentials of the bioeconomy relies on such progress. The fungal kingdom can be an
Palazuelos, Daniel; Dhillon, Ranu
Among many possible benefits, global health efforts can expand the skills and experience of U.S. clinicians, improve health for communities in need, and generate innovations in care delivery with relevance everywhere. Yet, despite high rates of interest among students and medical trainees to include global health opportunities in their training, there is still no clear understanding of how this interest will translate into viable and sustained global health careers after graduation. Building on a growing conversation about how to support careers in academic global health, this Perspective describes the practical challenges faced by physicians pursuing these careers after they complete training. Writing from their perspective as junior faculty at one U.S. academic health center with a dedicated focus on global health training, the authors describe a number of practical issues they have found to be critical both for their own career development and for the advice they provide their mentees. With a particular emphasis on the financial, personal, professional, and logistical challenges that young "expat" global health physicians in academic institutions face, they underscore the importance of finding ways to support these career paths, and propose possible solutions. Such investments would not only respond to the rational and moral imperatives of global health work and advance the mission of improving human health but also help to fully leverage the potential of what is already an unprecedented movement within academic medicine.
Full Text Available Despite a record-breaking 14.5 per cent increase in world merchandise exports, the effects of the financial crisis and global recession are still hampering faster economic recovery. Relatively high oil prices combined with persistent unemployment and measures designed to reduce budget deficits have undermined short-term growth prospects. While South–South trade continues to explode, trade imbalances – i.e. the gap between exports and imports – widened in 2010 compared to 2009 (though smaller than pre-crisis levels. Meanwhile, trade negotiations under the Doha Round have reached an impasse, generating uncertainties about the future of the World Trade Organization (WTO as a negotiating forum. Under these circumstances, should the system rethink its decision-making process founded upon the predominance of member states, the principle of consensus and the notion of single undertaking, as some critics have suggested? And, if so, how could such a reform agenda be initiated at the WTO? Moreover, beyond the negotiating function of the WTO, the paralysis of the system also raises urgent questions about the ability of the system to respond to pressing challenges of our times, such as trade and climate change, or food security and price volatility.
Ricroch, Agnès E; Hénard-Damave, Marie-Cécile
Most of the genetically modified (GM) plants currently commercialized encompass a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed against some biotic stresses (pest resistance, herbicide tolerance or both) and created by multinational companies. The same crops with agronomic traits already on the market today will continue to be commercialized, but there will be also a wider range of species with combined traits. The timeframe anticipated for market release of the next biotech plants will not only depend on science progress in research and development (R&D) in laboratories and fields, but also primarily on how demanding regulatory requirements are in countries where marketing approvals are pending. Regulatory constraints, including environmental and health impact assessments, have increased significantly in the past decades, delaying approvals and increasing their costs. This has sometimes discouraged public research entities and small and medium size plant breeding companies from using biotechnology and given preference to other technologies, not as stringently regulated. Nevertheless, R&D programs are flourishing in developing countries, boosted by the necessity to meet the global challenges that are food security of a booming world population while mitigating climate change impacts. Biotechnology is an instrument at the service of these imperatives and a wide variety of plants are currently tested for their high yield despite biotic and abiotic stresses. Many plants with higher water or nitrogen use efficiency, tolerant to cold, salinity or water submergence are being developed. Food security is not only a question of quantity but also of quality of agricultural and food products, to be available and accessible for the ones who need it the most. Many biotech plants (especially staple food) are therefore being developed with nutritional traits, such as biofortification in vitamins and metals. The main
Vesborg, Peter C. K.; Jaramillo, Thomas F.
The energy infrastructure for fossil fuels is well-established, accounting for approximately 87% of the 16 TW of power consumed globally. For renewable and sustainable energy conversion technologies to play a relevant role at the terrestrial scale, they must be able to scale to the TW level...... of deployment. This would place a significant demand on the current and future supply of raw materials (chemical elements) used by those technologies. Oftentimes, the average crustal abundance of a chemical element is cited as a measure of its scalability, however another important metric for scalability...... is the existence (of lack thereof) of mineable ores with a high concentration of the targeted element. This paper aims to provide an overview of the availability of all elements. This is accomplished via a compilation of data for global primary production rates for each element, as a measure of availability...
Leonard Bond; Kevin Kostelnik; Richard Holman
A secure and affordable energy supply is essential for achieving U.S. national security, in continuing U.S. prosperity and in laying the foundations to enable future economic growth. To meet this goal the next generation energy workforce in the U.S., in particular those needed to support instrumentation, controls and advanced operations and maintenance, is a critical element. The workforce is aging and a new workforce pipeline, to support both current generation and new build has yet to be established. The paper reviews the challenges and some actions being taken to address this need.
Han, Xuemei; Smyth, Regan L; Young, Bruce E; Brooks, Thomas M; Sánchez de Lozada, Alexandra; Bubb, Philip; Butchart, Stuart H M; Larsen, Frank W; Hamilton, Healy; Hansen, Matthew C; Turner, Will R
Recognizing the imperiled status of biodiversity and its benefit to human well-being, the world's governments committed in 2010 to take effective and urgent action to halt biodiversity loss through the Convention on Biological Diversity's "Aichi Targets". These targets, and many conservation programs, require monitoring to assess progress toward specific goals. However, comprehensive and easily understood information on biodiversity trends at appropriate spatial scales is often not available to the policy makers, managers, and scientists who require it. We surveyed conservation stakeholders in three geographically diverse regions of critical biodiversity concern (the Tropical Andes, the African Great Lakes, and the Greater Mekong) and found high demand for biodiversity indicator information but uneven availability. To begin to address this need, we present a biodiversity "dashboard"--a visualization of biodiversity indicators designed to enable tracking of biodiversity and conservation performance data in a clear, user-friendly format. This builds on previous, more conceptual, indicator work to create an operationalized online interface communicating multiple indicators at multiple spatial scales. We structured this dashboard around the Pressure-State-Response-Benefit framework, selecting four indicators to measure pressure on biodiversity (deforestation rate), state of species (Red List Index), conservation response (protection of key biodiversity areas), and benefits to human populations (freshwater provision). Disaggregating global data, we present dashboard maps and graphics for the three regions surveyed and their component countries. These visualizations provide charts showing regional and national trends and lay the foundation for a web-enabled, interactive biodiversity indicators dashboard. This new tool can help track progress toward the Aichi Targets, support national monitoring and reporting, and inform outcome-based policy-making for the protection of
Contemporary global politics is characterized by an increasing trend toward experimental forms of governance, with an emphasis on private governance. A plurality of private standards, codes of conduct and quality assurance schemes currently developed particularly, though not exclusively, by TNCs rep
Anantharaj, Valentine; Norman, Matthew; Evans, Katherine; Taylor, Mark; Worley, Patrick; Hack, James; Mayer, Benjamin
During 2013, high-resolution climate model simulations accounted for over 100 million "core hours" using Titan at the Oak Ridge Leadership Computing Facility (OLCF). The suite of climate modeling experiments, primarily using the Community Earth System Model (CESM) at nearly 0.25 degree horizontal resolution, generated over a petabyte of data and nearly 100,000 files, ranging in sizes from 20 MB to over 100 GB. Effective utilization of leadership class resources requires careful planning and preparation. The application software, such as CESM, need to be ported, optimized and benchmarked for the target platform in order to meet the computational readiness requirements. The model configuration needs to be "tuned and balanced" for the experiments. This can be a complicated and resource intensive process, especially for high-resolution configurations using complex physics. The volume of I/O also increases with resolution; and new strategies may be required to manage I/O especially for large checkpoint and restart files that may require more frequent output for resiliency. It is also essential to monitor the application performance during the course of the simulation exercises. Finally, the large volume of data needs to be analyzed to derive the scientific results; and appropriate data and information delivered to the stakeholders. Titan is currently the largest supercomputer available for open science. The computational resources, in terms of "titan core hours" are allocated primarily via the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) and ASCR Leadership Computing Challenge (ALCC) programs, both sponsored by the U.S. Department of Energy (DOE) Office of Science. Titan is a Cray XK7 system, capable of a theoretical peak performance of over 27 PFlop/s, consists of 18,688 compute nodes, with a NVIDIA Kepler K20 GPU and a 16-core AMD Opteron CPU in every node, for a total of 299,008 Opteron cores and 18,688 GPUs offering a cumulative 560
This report gives a brief overview of the global energy challenge and subsequently outlines how and where renewable energy could be developed to solve these issues. The report does not go into a lot of detail on these issues and hence, it is meant as an overview only. The report begins by outlining...... the causes of global climate change, concluding that energy-related emissions are the primary contributors to the problem. As a result, global energy production is analysed in more detail, discussing how it has evolved over the last 30 years and also, how it is expected to evolve in the coming 30 years....... Afterwards, the security of the world’s energy supply is investigated and it becomes clear that there is both an inevitable shortage of fossil fuels and a dangerous separation of supply and demand. The final topic discussed is renewable energy, since it is one sustainable solution to the global energy...
Most organizations today use spreadsheets in some form or another to support critical business processes. However the financial resources, and developmental rigor dedicated to them are often minor in comparison to other enterprise technology. The increasing focus on achieving regulatory and other forms of compliance over key technology assets has made it clear that organizations must regard spreadsheets as an enterprise resource and account for them when developing an overall compliance strategy. This paper provides the reader with a set of practical strategies for addressing spreadsheet compliance from an organizational perspective. It then presents capabilities offered in the 2007 Microsoft Office System which can be used to help customers address compliance challenges.
Developments in detector technologies aimed at solving challenges in present and future CERN experiments, particularly at the LHC, have triggered exceptional advances in the performance of medical imaging devices, allowing for a spectacular progress in in-vivo molecular imaging procedures, which are opening the way for tailored therapies of major diseases. This talk will briefly review the recent history of this prime example of technology transfer from HEP experiments to society, will describe the technical challenges being addressed by some ongoing projects, and will present a few new ideas for further developments and their foreseeable impact.
Hot on the heels of last year's Sustainable Development Goals and the Paris Agreement, representatives from the global conservation community met to set the conservation agenda that will help to implement these targets.
Jayne M. Rogerson
Full Text Available South Africa is among the most urbanized countries in Africa and has an urban population that is growing rapidly. The country’s urban challenges sometimes are considered as distinctive and separate to those of rest of Africa because of the apartheid legacy of a fragmented and racially splintered urban landscape. Nevertheless, 20 years after democratic transition the issues that confront its cities increasingly exhibit a set of sustainability challenges that typify those problems of many other fast-growing African urban areas. This introduction locates the collection of articles as a contribution to the expanding corpus of scholarship on urban South Africa.
Tilmes, Simone; Monaghan, Andrew; Done, James
Advanced Study Program/Early Career Scientist Assembly Workshop on Regional Climate Issues in Developing Countries; Boulder, Colorado, 19-22 October 2011 The Early Career Scientist Assembly (ECSA) and the Advanced Study Program of the National Center for Atmospheric Research (NCAR) invited 35 early-career scientists from nearly 20 countries to attend a 3-day workshop at the NCAR Mesa Laboratory prior to the World Climate Research Programme (WCRP) Open Science Conference in October 2011. The goal of the workshop was to examine a range of regional climate challenges in developing countries. Topics included regional climate modeling, climate impacts, water resources, and air quality. The workshop fostered new ideas and collaborations between early-career scientists from around the world. The discussions underscored the importance of establishing partnerships with scientists located in typically underrepresented countries to understand and account for the local political, economic, and cultural factors on which climate change is superimposed.
Hansen, Zaza Nadja Lee; Ahmed-Kristensen, Saeema
to rework, misunderstandings, miscommunication and lower quality. This paper investigates how the organisation can reduce the negative aspects of offshoring by presenting two possible approaches; one which lessens the exposure to situations in which these negative impacts happen and another which addresses...
A. Kolk (Ans)
textabstractThis chapter examines partnerships and their peculiarities, based on recent research from various disciplines, in the context of the large problems faced by (global) society. These problems are very complex, often cross national boundaries, and cannot easily be 'solved' by one single act
and militant and a more pragmatic and moderate strategy. In the global-local perspective we face two paradoxes. The first paradox is that in spite of the difference in union ideology, the outcome in terms of industrial relations (IR) institutions was rather similar in the sense that the auto industry contained......The paper aims to address the question whether the dynamic of autoworker unionism in South Korea and Malaysia was conditioned by, and eventually also influenced the globalization processes in the local auto industry? The conclusion is a contextualized "yes", and the core argument is the following......: The financial crisis in 1997 was the dramatic peak of financial globalization in East Asia in the 1990s, and it did accelerate the existing trend in Korea towards centralized unionism in the auto industry, while it suspended the trend in the Malaysian auto industry towards decentralized unionism. Although...
Full Text Available Essential Biodiversity Variables (EBVs are measurements required for study, reporting, and management of biodiversity change. They are being developed to support consistency, from the collection to the reporting of biodiversity data at the national, regional and global scales. However, "EBV stakeholders" need to strike a balance between 'doing innovative research' and 'having positive impact' on biodiversity management decisions. This paper reports on a workshop entitled Identifying joint pathways to address the challenges of biodiversity data provision and decision-making and presents the main workshop’s output, a “researcher’s brief” entitled Guiding principles for promoting the application of EBVs for current and future needs of decision-makers. These guiding principles are: Speak with a common voice; Clearly define what is an EBV and how it relates to indicators; Engage beyond the research world; Be realistic about what can be done now and later; Define criteria for good EBVs; Use EBV as a clearing house; Convey the limitations of EBVs; Clarify what impact EBVs should have; Be salient, credible, legitimate, iterative; Don't put an EBV skin on everything you do; Don't create too many EBVs; and Don't reduce EBVs to building blocks of indicators. This brief is of relevance to the wider GEO BON (Group on Earth Observation Biodoversity Observation Network community, and in particular those scientists/researchers interested in the application of EBVs.
Hemmings, S. N.; Banks, B.; Kendall, J.; Lee, C. M.; Irwin, D.; Toll, D. L.; Searby, N. D.
The NASA Capacity Building Program (Earth Science Division, Applied Sciences Program) works to enhance end-user capabilities to employ Earth observation and Earth science (EO/ES) data in decision-making. Open data access and user-tailored data delivery strategies are critical elements towards this end. User Experience (UX) and User Interface (UI) research methods can offer important contributions towards addressing data access challenges, particularly at the interface of science application/product development and product transition to end-users. This presentation focuses on developing nation contexts and describes methods, results, and lessons learned from two recent UX/UI efforts conducted in collaboration with NASA: the SERVIRglobal.net redesign project and the U.S. Water Partnership (USWP) Portal development effort. SERVIR, a collaborative venture among NASA, USAID, and global partners, seeks to improve environmental management and climate change response by helping governments and other stakeholders integrate EO and geospatial technologies into decision-making. The USWP, a collaboration among U.S. public and private sectors, harnesses U.S.-based resources and expertise to address water challenges in developing nations. SERVIR's study, conducted from 2010-2012, assessed and tested user needs, preferences, and online experiences to generate a more user-friendly online data portal at SERVIRglobal.net. The portal provides a central access interface to data and products from SERVIR's network of hubs in East Africa, the Hindu Kush Himalayas, and Mesoamerica. The second study, conducted by the USWP Secretariat and funded by the U.S. Department of State, seeks to match U.S.-based water information resources with developing nation stakeholder needs. The USWP study utilizes a multi-pronged approach to identify key design requirements and to understand the existing water data portal landscape. Adopting UX methods allows data distributors to design customized UIs that
Ball, James B.; Martinez, Zaida; Toyne, Brian
Although business schools are increasingly aware of the importance of globalization in educating future business leaders, their business programs have addressed globalization from a limited perspective that fails to provide students with a broader understanding of its impact on societies and its moral consequences. The conventional approach to the…
thank my loving wife and children for their undying support during my fellowship and career to this point. 1 Chapter 1 Addressing...Future Technology Challenges: Innovate or Die! I thoroughly disapprove of duels . If a man should challenge me, I would take him kindly and...forgivingly by the hand and lead him to a quiet place and kill him. - Mark Twain Duels are foolish. Mark Twain’s approach to conflict resolution is
Dr.Sc. Gjon Boriçi
Full Text Available Globalization is an ongoing phenomenon trying to redefine the economic, social, cultural and political dynamics of contemporary societies. The communication among countries and not only them, has been increased expanding political ties, making possible greater economic integration and wider cultural relations combined with augmented global wealth across the world. But, the process of globalization is in wider terms considered a beneficial one, but also viewed by some countries as a menace to national sovereignty and national culture. This paper tries to explain the obstacles to the process of globalization and its attendant benefits. Although globalization has arisen as a result of a more stable world, the factors that had contributed to its rise also help the factions interested to bring destabilization. In an academic approach in this article, between the research and comparative methods, I have been trying to get the maxims between economy, politics and diplomacy in their efforts of affecting the global era.
Martin, P; Widgren, J
Trends in international migration are presented in this multiregional analysis. Seven of the world's wealthiest countries have about 33% of the world's migrant population, but under 16% of the total world population. Population growth in these countries is substantially affected by the migrant population. The migration challenge is external and internal. The external challenge is to balance the need for foreign labor and the commitment to human rights for those migrants seeking economic opportunity and political freedom. The internal challenge is to assure the social adjustment of immigrants and their children and to integrate them into society as citizens and future leaders. Why people cross national borders and how migration flows are likely to evolve over the next decades are explained. This report also presents some ways that countries can manage migration or reduce the pressures which force people to migrate. It is recommended that receiving nations control immigration by accelerating global economic growth and reducing wars and human rights violations. This report examines the impact of immigration on international trade, aid, and direct intervention policies. Although migration is one of the most important international economic issues, it is not coordinated by an international group. The European experience indicates that it is not easy to secure international cooperation on issues that affect national sovereignty. It is suggested that countries desiring control of their borders should remember that most people never cross national borders to live or work in another country, that 50% of the world's migrants move among developing countries, and that countries can shift from being emigration to immigration countries. The author suggests that sustained reductions in migration pressure are a better alternative than the "quick fixes" that may invite the very much feared mass and unpredictable movements.
Swift, T.K. (Thomas)
The global business of chemistry has faced numerous challenges in recent years. This article addresses the near-term business environment in which the industry will operate as well as the implications for the global business of chemistry during 2006 and 2007.
@@ An energy report entitled Lighting the Way. Toward a Sustainable Energy Future by the InterAcademy Council (IAC), and the other one entitled Addressing the Challenge: Developing a Sustainable Energy System by CAS, were jointly released recently. The Sustainable Energy Forum: Panel Discussions on IAC/CAS Energy Reports, organized by CAS and held in Beijing on the afternoon of 22 October 2007, attracted around 50 distinguished participants, including senior governmental leaders, experts, and industrial representatives from both domestic and foreign energyrelated organizations.
Bioethics in a globalized world is meeting a number of challenges - fundamentalism in its different forms, and a focus on economic growth neglecting issues such as equity and sustainability, being prominent among them. How well are we as bioethicists equipped to make meaningful contributions in these times? The paper identifies a number of restraints and proceeds to probe potential resources such as the capability approach, care ethics, cosmopolitanism, and pragmatism. These elements serve to outline a perspective that focuses on the preconditions for flourishing human relationships as a way to address bioethical challenges in a globalized world.
Rubiano, Andrés M; Carney, Nancy; Chesnut, Randall; Puyana, Juan Carlos
Traumatic injury to the brain or spinal cord is one of the most serious public health problems worldwide. The devastating impact of 'trauma', a term used to define the global burden of disease related to all injuries, is the leading cause of loss of human potential across the globe, especially in low- and middle-income countries. Enormous challenges must be met to significantly advance neurotrauma research around the world, specifically in underserved and austere environments. Neurotrauma research at the global level needs to be contextualized: different regions have their own needs and obstacles. Interventions that are not considered a priority in some regions could be a priority for others. The introduction of inexpensive and innovative interventions, including mobile technologies and e-health applications, focused on policy management improvement are essential and should be applicable to the needs of the local environment. The simple transfer of a clinical question from resource-rich environments to those of low- and middle-income countries that lack sophisticated interventions may not be the best strategy to address these countries' needs. Emphasis on promoting the design of true 'ecological' studies that include the evaluation of human factors in relation to the process of care, analytical descriptions of health systems, and how leadership is best applied in medical communities and society as a whole will become crucial.
Full Text Available Pediatric sedation is a challenge which spans all continents and has grown to encompass specialties outside of anesthesia, radiology and emergency medicine. All sedatives are not universally available and local and national regulations often limit the sedation practice to specific agents and those with specific credentials. Some specialties have established certification and credentials for sedation delivery whereas most have not. Some of the relevant sedation guidelines and recommendations of specialty organizations worldwide will be explored. The challenge facing sedation care providers moving forward in the 21st century will be to determine how to apply the local, regional and national guidelines to the individual sedation practices. A greater challenge, perhaps impossible, will be to determine whether the sedation community can come together worldwide to develop standards, guidelines and recommendations for safe sedation practice.
Community-based health promotion is poorly theorised and lacks an agreed evidence-base. This paper examines characteristics of community-based health promotion and the challenges they present to evaluation. A review of health promotion evaluation leads to an exploration of more recent approaches, drawing on ideas from complexity theory and developmental evaluation. A reflexive analysis of three program evaluations previously undertaken as an evaluation consultant is used to develop a conceptual model to help in the design and conduct of health promotion evaluation. The model is further explored by applying it retrospectively to one evaluation. Findings suggest that the context-contingent nature of health promotion programs; turbulence in the community context and players; multiple stakeholders, goals and strategies; and uncertainty of outcomes all contribute to the complexity of interventions. Bringing together insights from developmental evaluation and complexity theory can help to address some evaluation challenges. The proposed model emphasises recognising and responding to changing contexts and emerging outcomes, providing rapid feedback and facilitating reflexive practice. This will enable the evaluator to gain a better understanding of the influence of context and other implementation factors in a complex setting. Use of the model should contribute to building cumulative evidence and knowledge in order to identify the principles of health promotion effectiveness that may be transferable to new situations.
Full Text Available A New Global Energy Economy is emerging, in which energy demand and supply issues will make regions of the world much more dependent upon each other. International extensive energetic interdependence on energy resources and networks grows in the global economy. Some $22 trillion of investment in supply infrastructure is needed to meet projected global demand until 2030. Mobilising all this investment will be challenging. Adherence to these policies will ensure that the global energy investments materializes, the necessary infrastructure is built, and the lengthening worldwide energy supply chain operates in security. Strong global energy policy is needed to move the world into a more sustainable energy path.
Editor Al-Jami'ah: Journal of Islamic Studies
Full Text Available Indeed, in maintaining their local values when faced with globalchallenges, Muslims, as a social entity, and Islam, as a set of dogma, havegiven birth to new phenomena, e.g. new interpretation of Islam withina new context. Additionally, this era of globalization has led religions,including Islam, to renew their gambit to cope reality, e.g. in the practicallife (sociological, political, economical and anthropological aspects,intellectual endeavors (philosophical and theological aspects, and in therenewal of dogmatic teachings (hermeneutical aspects.
Wang, Jian; Odell, Sandra J.
There are serious implications of the global economy for teacher education. In this paper, the authors identify some of the influences of the global economy on education and teacher education, point out responses to these, and discuss some of the resultant challenges from the vantage point of the United States.
Full Text Available Global tobacco control has led to a reduction in smoking prevalence and mortality in men, while the rates among women have not followed the same declining rates or patterns. Tobacco-induced diseases, including those unique to women (reproductive complications, cervical and breast cancer are becoming increasingly prevalent among women. Unfortunately, many tobacco control policies and cessation programs have been found to be less effective for women than men. This is alarming as disease risk for lung cancer, CVD, osteoporosis, and COPD, associated with smoking, is higher among women. Women are also more likely to be exposed to secondhand tobacco smoke and subsequent morbidity. Finally, quitting smoking appears to be harder for women than men. Current tobacco control and surveillance data come primarily from high resource countries. WHO estimates that in 2030, in low and medium resource countries, 7 out of 10 deaths will be smoking-related. While the prevalence of smoking in women is relatively low in these countries, more information is needed regarding their patterns of tobacco use uptake, and subsequent health outcomes, as theirs differ from men. Tobacco use in women is greatly influenced by social, cultural and political determinants, and needs to be conceptualized within an intersectional framework.
Piet J. Naudé
Full Text Available This article outlined key features of prophetic discourse and investigated whether this form of moral discourse adequately addresses issues of economic injustice. It is shown that the strength of prophetic discourse is its ability to denounce instances of injustice whilst at the same time announcing a God-willed alternative future. The ‘preferential option for the poor’ in Latin American liberation theologies is treated as a case study of the influence of prophetic discourse in contexts of perceived economic injustice. Also the core weaknesses of prophetic discourse are investigated, specifically its incomplete moral argument, weak moral analyses, silence on transition measures, and its inability to take a positive stance on reforms in the system from which itself benefits. In the final section it is concluded that prophetic discourse plays an indispensable role in addressing issues of global economic justice, but – taken by itself – it is not an adequate form of moral discourse to address concrete matters of justice.
Kuhrmann, Marco; Diebold, Philipp; Münch, Jürgen
For decades, Software Process Improvement (SPI) programs have been implemented, inter alia, to improve quality and speed of software development. To set up, guide, and carry out SPI projects, and to measure SPI state, impact, and success, a multitude of different SPI approaches and considerable...... a systematic mapping study on the state-of-the-art in SPI from a general perspective, we observed Global Software Engineering (GSE) becoming a topic of interest in recent years. Therefore, in this paper, we provide a detailed investigation of those papers from the overall systematic mapping study that were...... experience are available. SPI addresses many aspects ranging from individual developer skills to entire organizations. It comprises for instance the optimization of specific activities in the software lifecycle as well as the creation of organization awareness and project culture. In the course of conducting...
Butts, M. B.; Yamagata, K.; Kobor, J.; Fontenot, E.
Operational forecasting systems must provide reliable, accurate and timely flood forecasts for a range of catchments from small rapidly responding mountain catchments and urban areas to large, complex but more slowly responding fluvial systems. Flood forecasting systems have evolved from simple forecasting for flood mitigation to real-time decision support systems for real-time reservoir operations for water supply, navigation, hydropower, for managing environmental flows and habitat protection, cooling water and water quality forecasting. These different requirements lead to a number of challenges in applying distributed modelling in an operational context. These challenges include, the often short time available for forecasting that requires a trade-off between model complexity and accuracy on the one hand and on the other hand the need for efficient calculations to reduce the computation times. Limitations in the data available in real-time require modelling tools that can not only operate on a minimum of data but also take advantage of new data sources such as weather radar, satellite remote sensing, wireless sensors etc. Finally, models must not only accurately predict flood peaks but also forecast low flows and surface water-groundwater interactions, water quality, water temperature, optimal reservoir levels, and inundated areas. This paper shows how these challenges are being addressed in a number of case studies. The central strategy has been to develop a flexible modelling framework that can be adapted to different data sources, different levels of complexity and spatial distribution and different modelling objectives. The resulting framework allows amongst other things, optimal use of grid-based precipitation fields from weather radar and numerical weather models, direct integration of satellite remote sensing, a unique capability to treat a range of new forecasting problems such as flooding conditioned by surface water-groundwater interactions. Results
In this paper I argue that a global bioethics is possible. Specifically, I present the view that there are within feminist approaches to bioethics some conceptual and methodological tools necessary to forge a bioethics that embraces the health-related concerns of both developing and developed nations equally. To support my argument I discuss some of the challenges that have historically confronted feminists. If feminists accept the idea that women are entirely the same, then feminists present as fact the fiction of the essential "Woman." Not only does "Woman" not exist, -she" obscures important racial, ethnic, cultural, and class differences among women. However, if feminists stress women's differences too much, feminists lose the power to speak coherently and cogently about gender justice, women's rights, and sexual equality in general. Analyzing the ways in which the idea of difference as well as the idea of sameness have led feminists astray, I ask whether it is possible to avoid the Scylla of absolutism (imperialism, colonialism, hegemony) on the one hand and the Charybdis of relativism (postmodernism, fragmentation, Balkanization) on the other. Finally, after reflecting upon the work of Uma Narayan, Susan Muller Okin, and Martha Nussbaum, I conclude that there is a way out of this ethical bind. By focusing on women's, children's, and men's common human needs, it is possible to lay the foundation for a just and caring global bioethics.
Kim, Son H.; Edmonds, James A.
The response to climate change and the stabilization of atmospheric greenhouse gas concentrations has major implications for the global energy system. Stabilization of atmospheric carbon dioxide (CO2) concentrations requires a peak and an indefinite decline of global CO2 emissions. Nuclear energy, along with other technologies, has the potential to contribute to the growing demand for energy without emitting CO2. Nuclear energy is of particular interest because of its global prevalence and its current significant contribution, nearly 20%, to the world’s electricity supply. We have investigated the value of nuclear energy in addressing climate change, and have explored the potential challenges for the rapid and large-scale expansion of nuclear energy as a response to climate change. The scope of this study is long-term and the modeling time frame extends out a century because the nature of nuclear energy and climate change dictate that perspective. Our results indicate that the value of the nuclear technology option for addressing climate change is denominated in trillions of dollars. Several-fold increases to the value of the nuclear option can be expected if there is limited availability of competing carbon-free technologies, particularly fossil-fuel based technologies that can capture and sequester carbon. Challenges for the expanded global use of nuclear energy include the global capacity for nuclear construction, proliferation, uranium availability, and waste disposal. While the economic costs of nuclear fuel and power are important, non-economic issues transcend the issues of costs. In this regard, advanced nuclear technologies and new vision for the global use of nuclear energy are important considerations for the future of nuclear power and climate change.
McInnes, Colin; Kamradt-Scott, Adam; Lee, Kelley; Reubi, David; Roemer-Mahler, Anne; Rushton, Simon; Williams, Owain David; Woodling, Marie
With the emergence of global health comes governance challenges which are equally global in nature. This article identifies some of the initial limitations in analyses of global health governance (GHG) before discussing the focus of this special supplement: the framing of global health issues and the manner in which this impacts upon GHG. Whilst not denying the importance of material factors (such as resources and institutional competencies), the article identifies how issues can be framed in different ways, thereby creating particular pathways of response which in turn affect the potential for and nature of GHG. It also identifies and discusses the key frames operating in global health: evidence-based medicine, human rights, security, economics and development.
Argues that global challenge created by the pressure for change requires educators to understand the balance between continuity and constant change dependence and independence, individualism and community, homogeneity and heterogeneity. To achieve balanced learning and development, education should place greater emphasis on continuity,…
This paper places the question of ethical challenges in relation to the process of globalization concerning international education and the mobility of international students worldwide. It focuses on five areas of justice, namely, social and political justice, administrative justice, distributive justice, cultural justice and ecological justice.…
Barrios, Carlos H; Werutsky, Gustavo; Martinez-Mesa, Jeovany
The nature of clinical research has changed substantially over the last 2 decades, evolving from being centered almost exclusively in developed countries to a more global scenario that is increasingly involving less developed regions of the world. Pharmaceutical companies and some academic cooperative groups have been conducting challenging, large pivotal registration studies with multinational participation. The much more needed globalization of academic research demands particular attention and represents a worthwhile subject for a more profound discussion. The requirement of large sample sizes and the potential for fast recruitment leading to a speedy completion of clinical studies are probably the most important factors that have fueled globalization of studies. Reduced operational costs and the ability to expedite the regulatory approval of drugs in various countries or regions are also important drivers. Globalization of research should be seen as having a much wider effect in the societies involved, in particular, when we consider public health, economic, social, and ethical implications. Most importantly, the process of expanding the network of clinical research sites also fosters the integration and the development of closer relationships among investigators at a global level. We consider this an essential element that should remain a prominent element in the discussion. In this article, we address the underlying reasons for globalization and we highlight some of the scientific and ethical concerns arising as a consequence. Finally, some strategies to address and mitigate the challenges of conducting multinational clinical research are proposed.
Packer, Jasmin G.; Meyerson, Laura A.; Richardson, David M.
Much has been done to address the challenges of biological invasions, but fundamental questions (e.g., which species invade? Which habitats are invaded? How can invasions be effectively managed?) still need to be answered before the spread and impact of alien taxa can be effectively managed. Ques...... techniques. While the pace and scale of global change continues to escalate, strategic and collaborative global networks offer a powerful approach to inform responses to the threats posed by biological invasions....... scales. This paper proposes a framework for the development of ‘Global Networks for Invasion Science’ to help generate approaches to address these critical and fundamentally biogeographic questions. We define global networks on the basis of their focus on research questions at the global scale......, collection of primary data, use of standardized protocols and metrics, and commitment to long-term global data. Global networks are critical for the future of invasion science because of their potential to extend beyond the capacity of individual partners to identify global priorities for research agendas...
Giepmans. P.; Dussault, G.; Batenburg, R.; Frich, J.; Olivers, R.; Sermeus, W.
With health care services significantly changing, the challenge is to initiate innovative, situational and integrated workforce forecasting and planning. Many health systems require a shift in mindset to move to the planning of skill mixes for health care professionals. This implies great challenges
Groff, Jennifer; Mouza, Chrystalla
Creating effective learning environments with technology remains a challenge for teachers. Despite the tremendous push for educators to integrate technology into their classrooms, many have yet to do so and struggle to find consistent success with technology-based instruction. The challenges to effective technology integration have been…
Clayton, Susan; Devine-Wright, Patrick; Swim, Janet; Bonnes, Mirilia; Steg, Linda; Whitmarsh, Lorraine; Carrico, Amanda
Environmental challenges, though daunting, present an important area for psychologists to apply their knowledge. Psychological theories, research methods, and interventions are essential for examining the questions about human impacts, tendencies, and capacities that are integral to constructing eff
Yearley, Shelley; Bruce, Catherine D.
Teaching and learning fraction concepts provides challenges in primary schools all over the world. In this article, Shelley Yearley and Catherine Bruce describe a fractions-based research project conducted in Ontario, Canada.
Technology must be used as a teaching and learning tool to help students succeed. However, educators must be proactive in identifying some of the pitfalls of technology, such as information illiteracy. The phenomenological study covers how English instructors from Indianapolis, who teach first year students, address information literacy and the…
The domestic appliances industry is a mature industry. Changes in the business environment such as political, law, cultural, social, ecological and technological influences have an effect on the future development of this industry. Challenges to producers in this industry are oriented towards the further globalisation of the business, managing processes, new product and innovations development, and towards establishing and empowerment of the product brands. Global trends in the use of some na...
Hemmeter, Mary Louise; Ostrosky, Michaelene M.; Corso, Robert M.
The purpose of this article is to offer preschool teachers strategies for preventing challenging behavior and supporting the development of social skills and emotional competencies. This article is framed in a question and answer format using questions from teachers who the authors have worked with in the past. These questions and strategies are…
Carter, Steven J.; Henrichsen, Lynn E.
Reticence frequently prevents adult ESL learners from learning as much as they otherwise might. The nature of second-language learning requires frequent performance that may challenge students' self-concepts, leading to reticence and self-consciousness. To reduce or prevent this problem, teachers must employ appropriate pedagogical and classroom…
Demchenko, Y.; Zhao, Z.; Grosso, P.; Wibisono, A.; de Laat, C.
This paper discusses the challenges that are imposed by Big Data Science on the modern and future Scientific Data Infrastructure (SDI). The paper refers to different scientific communities to define requirements on data management, access control and security. The paper introduces the Scientific Dat
Scott, Terrance M.; Hirn, Regina G.
When dealing with children who exhibit challenging behaviors there are no known interventions that work for all students or at all times. Thus, intervention for these students is often implemented in a trial and error manner. This article provides a logic for considering probability as a factor in selecting strategies. Understanding that some…
Global warming poses one of the most serious threats to the globalenvironment ever faced in human history. We have recognized the issue intime to do something about it, and we have methods and resources tomitigate global warming. Every decade we delay in taking action, we arecommitting the planet to additional warming that future generations have todeal with offer compelling evidence from a large body of information thatglobal climate change caused by global warming is already underway andreq...
Full Text Available Abstract Adoptive T cell therapy involves the ex vivo selection and expansion of effector cells for the treatment of patients with cancer. In this review, the advantages and limitations of using antigen-specific T cells are discussed in counterpoint to vaccine strategies. Although vaccination strategies represent more readily available reagents, adoptive T cell therapy provides highly selected T cells of defined phenotype, specificity and function that may influence their biological behavior in vivo. Adoptive T cell therapy offers not only translational opportunities but also a means to address fundamental issues in the evolving field of cancer immunotherapy.
Florini, Ann; Sovacool, Benjamin K. [Centre on Asia and Globalisation, Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore 259772 (Singapore)
This article conceptualizes the energy problems facing society from a global governance perspective. It argues that a notion of 'global energy governance,' taken to mean international collective action efforts undertaken to manage and distribute energy resources and provide energy services, offers a meaningful and useful framework for assessing energy-related challenges. The article begins by exploring the concepts of governance, global governance, and global energy governance. It then examines some of the existing institutions in place to establish and carry out rules and norms governing global energy problems and describes the range of institutional design options available to policymakers. It briefly traces the role of a selection of these institutions, from inter-governmental organizations to summit processes to multilateral development banks to global action networks, in responding to energy issues, and points out their strengths and weaknesses. The article concludes by analyzing how the various approaches to global governance differ in their applicability to addressing the conundrums of global energy problems. (author)
Belvedere, D. R.; Houser, P. R.; Schiffer, R. A.; Entin, J. K.
Dramatically changing climates has had an indelible impact on North America's water crisis; the rapid melting of glaciers has profound implications for the sustainability of Canada's rivers. However, projective increases in water demand from increasing population, industrial energy, and agriculture needs may have four times more impact on the water supply-demand imbalance than climate change. Reliable prediction of hydrologic change and extremes is of critical importance for policy and decision makers to adapt to these future water challenges. However, the models that we use to understand and forecast water availability, flooding, and drought are simply not up to the task of addressing our most pressing societal issues and national security. We need a decisive and coordinative effort to systematically improve water cycle prediction skill, coupled with reliable methodologies to translate those predictions into actionable water supply and quality information to support sustainable water management - this is a primary motivation for the proposed North American Water Program (NAWP). To decisively address these challenges, we recommend that NAWP coalesce an interdisciplinary, international and interagency effort to make significant contributions to continental-to-decision-scale hydroclimate science and solutions. By entraining, integrating and coordinating the vast array of interdisciplinary observationable and prediction resources available, NAWP will significantly advance skill in predicting, assessing, and managing variability and changes in North American water resources, as an integral part of the global climate system. We adopt three challenges to organize NAWP efforts. The first deals with developing a scientific basis and tools for mitigating and adapting to changes in the water supply-demand balance. The second challenge is benchmarking; to use incomplete and uncertain observations to assess water storage and quality dynamics, and to characterize the
Cozzi, Giovanni; McKinley, Terry
This Policy Brief is focused on the need to reduce macroeconomic imbalances both globally and within Europe. In doing so, it employs the CAM global macroeconometric model to make projections of trends over roughly the next ten years, i.e., through 2025.
Clayton, Susan; Devine-Wright, Patrick; Swim, Janet; Bonnes, Mirilia; Steg, Linda; Whitmarsh, Lorraine; Carrico, Amanda
Environmental challenges, though daunting, present an important area for psychologists to apply their knowledge. Psychological theories, research methods, and interventions are essential for examining the questions about human impacts, tendencies, and capacities that are integral to constructing effective responses to these challenges. Although a great deal of relevant research has been done, there is scope for psychologists to be more extensively involved. Following a brief review of existing research, we outline some important new directions. We also highlight 2 key divergences, arguing that psychological research needs to expand beyond a traditional, theory-based and decontextualized approach to environmental issues to incorporate a contextualized or "place-based" approach and a willingness to collaborate in interdisciplinary research teams that focus on specific environmental problems. Suggestions for promoting such interdisciplinary collaborations are reviewed. We encourage psychologists to expand their engagement with important environmental issues through multiple research approaches in order to further their understanding of human behavior, contributions to human well-being, and relevance to other disciplines and to society.
Petersen, Christina I.; Gorman, Kristen S.
This chapter provides practical strategies for addressing common challenges that arise for teachers in active learning classrooms. Our strategies come from instructors with experience teaching in these environments.
Peeran, Syed Wali; Altaher, Omar Basheer; Peeran, Syed Ali; Alsaid, Fatma Mojtaba; Mugrabi, Marei Hamed; Ahmed, Aisha Mojtaba; Grain, Abdulgader
Libya is a vast country situated in North Africa, having a relatively better functioning economy with a scanty population. This article is the first known attempt to review the current state of oral health care in Libya and to explore the present trends and future challenges. Libyan health system, oral health care, and human resources with the present status of dental education are reviewed comprehensively. A bibliographic study of oral health research and publications has been carried out. The results point toward a common indicator that oral health-related research is low. Strategies have to be developed to educate the medical and dental professionals, to update the current curriculum and enable the system to be competent in all aspects of oral health care management.
Minhas Gunjeet S
Full Text Available Abstract Background Experience with public engagement activities regarding the risks and benefits of science and technology (S&T is growing, especially in the industrialized world. However, public engagement in the developing world regarding S&T risks and benefits to explore health issues has not been widely explored. Methods This paper gives an overview about public engagement and related concepts, with a particular focus on challenges and benefits in the developing world. We then describe an Internet-based platform, which seeks to both inform and engage youth and the broader public on global water issues and their health impacts. Finally, we outline a possible course for future action to scale up this and similar online public engagement platforms. Results The benefits of public engagement include creating an informed citizenry, generating new ideas from the public, increasing the chances of research being adopted, increasing public trust, and answering ethical research questions. Public engagement also fosters global communication, enables shared experiences and methodology, standardizes strategy, and generates global viewpoints. This is especially pertinent to the developing world, as it encourages previously marginalized populations to participate on a global stage. One of the core issues at stake in public engagement is global governance of science and technology. Also, beyond benefiting society at large, public engagement in science offers benefits to the scientific enterprise itself. Conclusion Successful public engagement with developing world stakeholders will be a critical part of implementing new services and technologies. Interactive engagement platforms, such as the Internet, have the potential to unite people globally around relevant health issues.
Mach, Henryk; Arvinte, Tudor
As the share of therapeutic proteins in the arsenal of modern medicine continue increasing, relatively little progress has been made in the development of analytical methods that would address specific needs encountered during the development of these new drugs. Consequently, the researchers resort to adaptation of existing instrumentation to meet the demands of rigorous bioprocess and formulation development. In this report, we present a number of such adaptations as well as new instruments that allow efficient and precise measurement of critical parameters throughout the development stage. The techniques include use of atomic force microscopy to visualize proteinacious sub-visible particles, use of extrinsic fluorescent dyes to visualize protein aggregates, particle tracking analysis, determination of the concentration of monoclonal antibodies by the analysis of second-derivative UV spectra, flow cytometry for the determination of subvisible particle counts, high-throughput fluorescence spectroscopy to study phase separation phenomena, an adaptation of a high-pressure liquid chromatography (HPLC) system for the measurement of solution viscosity and a variable-speed streamlined analytical ultracentrifugation method. An ex vivo model for understanding the factors that affect bioavailability after subcutaneous injections is also described. Most of these approaches allow not only a more precise insight into the nature of the formulated proteins, but also offer increased throughput while minimizing sample requirements.
Parker, Patricia A; Aaron, Joann; Baile, Walter F
Women with breast cancer have become increasingly more involved on a national and local level in advocating for resources to fight cancer. However, in the context of the relationship with their physicians and other cancer caregivers, much remains to be done in providing them with adequate support. In this paper, we highlight the difficulties in communication related to breast cancer and describe strategies and approaches that may be helpful in improving the communication throughout the cancer trajectory. Specifically, breast cancer patients have high unmet information needs relevant to health information and dissatisfaction with the actual information they receive from their providers. These needs seem even more pronounced when patients are older, of lower socio-economic class and from differing cultural backgrounds which may affect their ability to express their desires for information and desire to be involved in decision-making about their treatment. Other communication challenges can be envisioned as occurring at key points across the cancer trajectory: diagnosis disclosure, treatment failure, transition to palliative care, and end of life discussions. These involve techniques as basic as how to establish trust and rapport and determine a patient's information and decision-making preferences and as complex as giving bad news. These strategies are now viewed as essential skills in that they can affect patient distress and quality of life, satisfaction, and malpractice litigation as well as practitioner stress and burnout.
Carmel, Sara; Lowenstein, Ariela
Like other developed nations, Israel has rapidly aged. This demographic revolution has created new challenges for Israeli society. We describe the societal background, including the emerging societal needs, solutions, and problems, as well as the professional principles, which guided us in developing the first two Israeli academic programs in gerontology in Beer-Sheva and Haifa. We further discuss the structures of both programs and their accomplishments. Although both programs were guided by identical needs and principles, geared toward the same multidisciplinary target population, and are dynamic and responsive to the emerging needs and difficulties, they differ in structure. While Haifa's program is flexible, Beer-Sheva's program is structured and divided into three distinct programs, of which only one-the research track-is designed and tailored to the students' interest. The two programs have contributed to increasing interest and research in aging in Israel, enhancing professional cooperation within the universities and with the international scientific community, opening the labor market for the programs' graduates, creating fruitful collaborations with community services, and accelerating the improvement of elderly quality of care.
After the invention of quantum mechanics, P. A. M. Dirac made the following observation: ``The underlying physical laws necessary for the mathematical theory of a large part of physics and the whole of chemistry are thus completely known, and the difficulty is only that the exact application of these laws leads to equations much too complicated to be soluble. It therefore becomes desirable that approximate practical methods of applying quantum mechanics should be developed, which can lead to an explanation of the main features of complex atomic systems...'' The creation of ``approximate practical methods'' in response to Dirac's challenge has included the one electron picture, density functional theory and the pseudopotential concept. The combination of such methods in conjunction with contemporary computational platforms and new algorithms offer the possibility of predicting properties of materials solely from knowledge of the atomic species present. I will give an overview of progress in this field with an emphasis on materials at the nanoscale. Support from the Department of Energy and the National Science Foundation is acknowledged.
Mackenzie Karen J
Full Text Available Abstract Allergic sensitisation usually begins early in life. The number of allergens a patient is sensitised to can increase over time and the development of additional allergic conditions is increasingly recognised. Targeting allergic disease in childhood is thus likely to be the most efficacious means of reducing the overall burden of allergic disease. Specific immunotherapy involves administering protein allergen to tolerise allergen reactive CD4+ T cells, thought key in driving allergic responses. Yet specific immunotherapy risks allergic reactions including anaphylaxis as a consequence of preformed allergen-specific IgE antibodies binding to the protein, subsequent cross-linking and mast cell degranulation. CD4+ T cells direct their responses to short "immunodominant" peptides within the allergen. Such peptides can be given therapeutically to induce T cell tolerance without facilitating IgE cross-linking. Peptide immunotherapy (PIT offers attractive treatment potential for allergic disease. However, PIT has not yet been shown to be effective in children. This review discusses the immunological mechanisms implicated in PIT and briefly covers outcomes from adult PIT trials. This provides a context for discussion of the challenges for the application of PIT, both generally and more specifically in relation to children.
Full Text Available Objective ‐ This paper explores the various issues and challenges arising from e‐book cataloguing experienced at the University of Windsor’s Leddy Library and the Ontario Council of University Libraries (OCUL. This discussion uses an evidence based approach to identify and resolve issues relevant to academic libraries as well as to consortia. With the ever rising popularity of e‐books within academic libraries, cataloguing librarians are actively seeking more effective methods of managing this new electronic medium, including the development of new cataloguing policies and procedures. This paper will explore the various issues and challenges surrounding e‐book cataloguing and processing within academic libraries, and will identify new policies and procedures that may be used to effectively assist in e‐book management.Methods ‐ This paper presents a case study of e‐book cataloguing practices undertaken by a Canadian academic library and the consortium with which it is affiliated. Towards this end, the University of Windsor’s Leddy Library will be the prime focus of this study, with its establishment of a new e‐book MARC records database. The research is based on the results of the e‐book MARC project undertaken by the Leddy Library and the Ontario Council of University Libraries (OCUL.Through analysis of various suppliers’ MARC records and the actual implementation of the e‐book MARC project, the authors developed and evaluated a new approach to e‐book cataloguing for use in academic libraries.Results ‐ This practice‐based approach towards the development of a new method of e‐book cataloguing required continual modification and examination of e‐book MARC records within the target library. The Leddy Library’s e‐book MARC project provided an excellent opportunity to test the library’s existing cataloguing standards and procedures for print format, while at the same time, identifying related e‐books issues
Lu, Yonglong; Jenkins, Alan; Ferrier, Robert C; Bailey, Mark; Gordon, Iain J; Song, Shuai; Huang, Jikun; Jia, Shaofeng; Zhang, Fusuo; Liu, Xuejun; Feng, Zhaozhong; Zhang, Zhibin
China's increasingly urbanized and wealthy population is driving a growing and changing demand for food, which might not be met without significant increase in agricultural productivity and sustainable use of natural resources. Given the past relationship between lack of access to affordable food and political instability, food security has to be given a high priority on national political agendas in the context of globalization. The drive for increased food production has had a significant impact on the environment, and the deterioration in ecosystem quality due to historic and current levels of pollution will potentially compromise the food production system in China. We discuss the grand challenges of not only producing more food but also producing it sustainably and without environmental degradation. In addressing these challenges, food production should be considered as part of an environmental system (soil, air, water, and biodiversity) and not independent from it. It is imperative that new ways of meeting the demand for food are developed while safeguarding the natural resources upon which food production is based. We present a holistic approach to both science and policy to ensure future food security while embracing the ambition of achieving environmental sustainability in China. It is a unique opportunity for China to be a role model as a new global player, especially for other emerging economies.
Recent educational policy and practice have established an extended role for all subjects in addressing children and young peoples' academic and interpersonal development, with strategies facilitating key skills and wider learning across areas of Citizenship and Personal, Social and Health education providing an integrated approach to education…
Christensen, John M. (Risoe DTU, Roskilde (Denmark)); Davidson, O. (Univ. of Sierra Leone, IPCC (Sierra Leone))
The global energy scene is currently dominated by two overriding concerns that are strongly affecting decisions about energy development priorities: 1) Climate change 2) Energy security. This is especially true for industrialized countries and the more rapidly developing economies while many developing countries are facing really basic energy development constraints giving quite a different meaning to the concept of energy security. There is broad global recognition of the need to support these countries in their efforts to increase access to cleaner and more efficient forms of energy for the more than 1,6 billion people currently having no access to electricity and largely relying on traditional forms of biomass for basic energy services, but progress is slow in many regions. The three areas, security, climate and poverty are in several ways interlinked, and ideally national energy policies and development programmes should address all the above issues - or at least not have negative effects in any area. In practice, however, many national policy landscapes have been dominated by just one of these factors. In the political debate the access issue is often seen as a potential climate problem, but most studies indicate that access to basic energy services for the poorest one billion people, even based on fossil resources, will make very marginal contributions to global GHG emissions. The more relevant and pressing political concern is how to limit global emissions and allow the emerging economies to continue their economic growth, but as discussed in this report the technological options will be available and solutions depend on political will and agreements on sharing the technologies and financial resources. (au)
Andrienko, O.; Garelina, S.; Gysev, A.; Zakharyan, R.; Kazaryan, M.; Sachkov, V.
This work scales the present globalism of ecological and energetic problems. The ecological problem is connected with environment pollution by polymeric waste. The energetic problem - with traditional approaches of modern energetic, in particular, use of fossil fuel for energy production and concentration of capacities for ensuring overall performance of global power supply systems that doesn't guarantee a sustainable development of power for long prospect, doesn't provide power safety of the country. The second part of work is devoted to a choice of the most effective solutions of the present global problems. The authors have proposed the plasma-chemical method of the polymer waste processing and developed a schematic diagram of the reactor. The paper contains the results of the theoretical calculation of the polymer waste processing products. The reagents, allowing to obtain hydrogen and other liquid products from polymer waste are selected. It is proposed to use rare elements for increasing the efficiency of hydrogen production from polymer waste. The results of the calculation of the efficiency of hydrogen production from polymer waste using molybdenum are revealed in the paper.
Gerba Charles P; Riley Mark R; Elimelech Menachem
Abstract The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of p...
Waddell, Steve; Cornell, Sarah; Hsueh, Joe; Ozer, Ceren; McLachlan, Milla; Birney, Anna
Most action to address contemporary complex challenges, including the urgent issues of global sustainability, occurs piecemeal and without meaningful guidance from leading complex change knowledge and methods. The potential benefit of using such knowledge is greater efficacy of effort and investment. However, this knowledge and its associated tools and methods are under-utilized because understanding about them is low, fragmented between diverse knowledge traditions, and often requires shifts in mindsets and skills from expert-led to participant-based action. We have been engaged in diverse action-oriented research efforts in Large System Change for sustainability. For us, "large" systems can be characterized as large-scale systems - up to global - with many components, of many kinds (physical, biological, institutional, cultural/conceptual), operating at multiple levels, driven by multiple forces, and presenting major challenges for people involved. We see change of such systems as complex challenges, in contrast with simple or complicated problems, or chaotic situations. In other words, issues and sub-systems have unclear boundaries, interact with each other, and are often contradictory; dynamics are non-linear; issues are not "controllable", and "solutions" are "emergent" and often paradoxical. Since choices are opportunity-, power- and value-driven, these social, institutional and cultural factors need to be made explicit in any actionable theory of change. Our emerging network is sharing and building a knowledge base of experience, heuristics, and theories of change from multiple disciplines and practice domains. We will present our views on focal issues for the development of the field of large system change, which include processes of goal-setting and alignment; leverage of systemic transitions and transformation; and the role of choice in influencing critical change processes, when only some sub-systems or levels of the system behave in purposeful ways
limited. The effects of cloud formations, precipitation, the role of the oceans, or the sun are still not well known and often inadequately represented in the climate models, although all play a major role in determining our climate. Origin, existence.... The model shows that after ~8,000 years B.P. the 1 Global Warming and Role of Micropaleontologists sediments of ~10,000 and ~12,000 years B.P. age were eroded from the deeper region by severe storm(s), transported and redeposited in shallower region thus...
Galichon, Ines; Lacroix, Olivier; Wiedmer, Damien
Globally 1.3 billion people do not have access to electricity. If this figure is projected to decline 1 billion by 2030, the global population who relies on the traditional use of biomass for cooking is expected to substantially increase, from 2.6 billion to 2.7 billion people. In its commitment to energy access, ENEA published a synthesis on the current situation and the further development perspectives of energy access worldwide, a crucial issue of human and economic development and an opportunity for the private sector. This synthesis present the ecosystem of the actors involved in the improvement of energy access and the technical solutions that serve the needs of this high-potential market. The five main challenges energy access has to address are presented in this publication: energy prices, equipment financing, distribution, change of scale and environmental performances.
Our world is becoming increasingly global. This may sound like a clich'e, yet it is true nonetheless, and poses unprecedented challenges for graduate education. For the new generation of researchers, teachers and professionals to be successful they must be prepared in more than the content area of their chosen field. They must also acquire proficiency in global awareness, cultural literacy, multicultural teamwork and language facility. These global skill sets form the basis for effective multicultural collaboration and will become increasingly important even for those who do not intend to study or work abroad. Knowledge has become more portable in the internet age; large data bases and reports can be accessed in real time from various locations around the globe; information is exchanged in multifaceted knowledge networks; collaborative research takes place within and outside of the traditional venue of the research university in the private sector, research institutes, and associations; research networks span multiple disciplines as progress invariably occurs at the intersection of previously discrete fields of inquiry. Global collaboration thus is no longer dependent on the physical proximity of collaborators but can take place anywhere any time. This then requires yet another set of skills, namely the ability to adapt to change, exhibit flexibility and transfer skills to a range of contexts and applications. Effective graduate education must address these realities and expose students to learning opportunities that will enable them to acquire these much needed global skills sets.
When we examine the impacts of space weather on society, do we really understand the risks? Can past experiences reliably predict what will happen in the future? As the complexity of technology increases, there is the potential for it to become more fragile, allowing for a single point of failure to bring down the entire system. Take the Global Positioning System (GPS) as an example. GPS positioning, navigation, and timing have become an integral part of daily life, supporting transportation and communications systems vital to the aviation, merchant marine, cargo, cellular phone, surveying, and oil exploration industries. Everyday activities such as banking, mobile phone operations, and even the control of power grids are facilitated by the accurate timing provided by GPS. Understanding the risks of space weather to GPS and the many economic sectors reliant upon it, as well as how to build resilience, was the focus of a policy workshop organized by the American Meteorological Society (AMS) and held on 13-14 October 2010 in Washington, D. C. The workshop brought together a select group of policy makers, space weather scientists, and GPS experts and users.
de Jong, J.T.V.M.
This article addresses four major challenges for efforts to create synergy between the global mental health movement and cultural psychiatry. First, although they appear to share domains of mutual interest, the worlds of global mental health and cultural psychiatry have distinct lineages. Expanding
Brauch, H.G.; Oswald Spring, Ú.; Mesjasz, C.; Grin, J.; Kameri-Mbote, P.; Chourou, B.; Dunay, P.; Birkmann, J.
This policy-focused Global Environmental and Human Security Handbook for the Anthropo-cene (GEHSHA) addresses new security threats, challenges, vulnerabilities and risks posed by global environmental change and disasters. In 6 forewords, 5 preface essays 95 peer reviewed chapcountries analyse in 10
Geoffrey Phillip Dobson
Full Text Available Despite a technically perfect procedure, surgical stress can determine the success or failure of an operation. Surgical trauma is often referred to as the neglected step-child of global health in terms of patient numbers, mortality, morbidity and costs. A staggering 234 million major surgeries are performed every year, and depending upon country and institution, up to 4% of patients will die before leaving hospital, up to 15% will have serious post-operative morbidity, and 5 to 15% will be readmitted within 30 days. These percentages equate to around 1000 deaths and 4000 major complications every hour, and it has been estimated that 50% may be preventable. New frontline drugs are urgently required to make major surgery safer for the patient and more predictable for the surgeon. We review the basic physiology of the stress response from neuroendocrine to genomic systems, and discuss the paucity of clinical data supporting the use of statins, beta-adrenergic blockers and calcium channel blockers. Since cardiac-related complications are the most common, particularly in the elderly, a key strategy would be to improve ventricular-arterial coupling to safeguard the endothelium and maintain tissue oxygenation. Reduced O2 supply is associated with glycocalyx shedding, decreased endothelial barrier function, fluid leakage, inflammation and coagulopathy. A healthy endothelium may prevent these secondary hit complications, including possibly immunosuppression. Thus the four pillars of whole body resynchronization during surgical trauma, and targets for new therapies, are: 1 the CNS, 2 the heart, 3 arterial supply and venous return functions, and 4 the endothelium. This is termed the Central-Cardio-Vascular-Endothelium (CCVE coupling hypothesis. Since similar sterile injury cascades exist in critical illness, accidental trauma, hemorrhage, cardiac arrest, infection and burns, new drugs that improve CCVE coupling may find wide utility in civilian and
Kozlowski, Wojciech; Mekhov, Igor B
We show that light scattering from an ultracold gas reveals not only density correlations, but also matter-field interference at its shortest possible distance in an optical lattice, which defines key properties such as tunneling and matter-field phase gradients. This signal can be enhanced by concentrating probe light between lattice sites rather than at density maxima. As addressing between two single sites is challenging, we focus on global nondestructive scattering, allowing probing order parameters, matter-field quadratures and their squeezing. The scattering angular distribution displays peaks even if classical diffraction is forbidden and we derive generalized Bragg conditions. Light scattering distinguishes all phases in the Mott insulator - superfluid - Bose glass phase transition.
Modern societies aim to solve the global challenges of the 21st century with sustainable solutions such as resource efficiency, use of renewable energy sources and recycling. Engineers are called upon to create the cutting edge technological solutions that can help to address these challenges. In developed as well as in developing countries,…
AMO is developing advanced technologies that cut energy use and carbon emissions in some of the most energy-intensive processes within U.S. manufacturing. The brochure describes the AMO R&D projects that address these challenges.
Goldhaber, M. B.; Banwart, S. A.
Earth's Critical Zone (CZ) is the thin outer veneer of our planet from the top of the tree canopy to the bottom of our drinking water aquifers that supports almost all human activity. Despite its fundamental importance to terrestrial life, understanding of the operation of the coupled geologic, hydrologic, topographic, and biotic CZ processes across time and space is far from complete. These interactions are complex and they establish a mechanistic 'chain of impact' that transmits the effects of environmental change throughout the CZ. Characterization of these processes is made more urgent by the fact that globally, the CZ is experiencing ever-increasing pressure from growth in human population and wealth. Within the next four decades, demand for food and fuel is expected to double along with a more than 50% increase in demand for clean water. Understanding, predicting and managing intensification of land use and associated economic services, while mitigating and adapting to rapid climate change, is now one of the most pressing societal challenges of the 21st century. In this talk we summarize the profound global societal impacts to the Earth's near surface arising from exponential human population growth, increasing affluence, and technological advance, to provide context for discussions on constructing an array of CZ observatories to both characterize fundamental critical zone processes and forecast the effects of planetary change. We will suggest goals and options relevant to planning for a future international array of CZ observatories and a research agenda that matches the urgency of the projected resource demands and environmental pressures of the coming four decades.
Terblanche, Deon; Jalkanen, Liisa
counterparts. The urban environment also provides numerous opportunities. One example being the better use of weather and environmental predictions to proactively optimize the functioning of the urban environment in terms of the use of energy, goods and services. Another is the providing of air quality forecasting services to benefit the health of the population. To address the challenges and opportunities facing megacities and large urban complexes, WMO has established the Global Atmosphere Watch (GAW) Urban Research Meteorology and Environment (GURME). Air pollution questions in urban areas, in particular megacities, is the main focus, building observational and modelling capabilities in developing countries through pilot projects and transfer of scientific expertise. GURME contributes to improving capabilities to handle meteorological and related features of air pollution by addressing end-to-end aspects of air quality, linking observational capabilities with the needs of chemical weather prediction, with the goal of providing high quality air quality services. Using examples from around the world but with specific reference to Africa, the unique challenges and opportunities related to megacities and large urban complexes, as perceived by the World Meteorological Organization (WMO) are highlighted.
Janjic, Zavisa; Djurdjevic, Vladimir; Vasic, Ratko; Black, Tom
") with significant amplitudes can develop. Due to their large scales, that are comparable to the scales of the dominant Rossby waves, such fictitious solutions are hard to identify and remove. Another new challenge on the global scale is that the limit of validity of the hydrostatic approximation is rapidly being approached. Having in mind the sensitivity of extended deterministic forecasts to small disturbances, we may need global non-hydrostatic models sooner than we think. The unified Non-hydrostatic Multi-scale Model (NMMB) that is being developed at the National Centers for Environmental Prediction (NCEP) as a part of the new NOAA Environmental Modeling System (NEMS) will be discussed as an example. The non-hydrostatic dynamics were designed in such a way as to avoid over-specification. The global version is run on the latitude-longitude grid, and the polar filter selectively slows down the waves that would otherwise be unstable. The model formulation has been successfully tested on various scales. A global forecasting system based on the NMMB has been run in order to test and tune the model. The skill of the medium range forecasts produced by the NMMB is comparable to that of other major medium range models. The computational efficiency of the global NMMB on parallel computers is good.
Magnusson, R S
Chronic diseases, including cardiovascular disease, diabetes and cancer, are the leading cause of death and disability in both the developed and developing world (excluding sub-Saharan Africa). At present, the global framework for action on chronic disease is strongly 'World Health Organization (WHO)-centric', defined by two WHO initiatives: the WHO Framework Convention on Tobacco Control, and the Global Strategy on Diet, Physical Activity and Health. This paper explores the difficulties of developing a collective response to global health challenges, and draws out some implications for chronic disease. It highlights how political partnerships and improved governance structures, economic processes, and international laws and standards function as three, concurrent pathways for encouraging policy implementation at country level and for building collective commitment to address the transnational determinants of chronic disease. The paper evaluates WHO's initiatives on chronic disease in terms of these pathways, and makes the case for a global compact on chronic disease as a possible structure for advancing WHO's free-standing goal of reducing mortality from chronic diseases by an additional 2% between 2005 and 2015. Beneath this overarching structure, the paper argues that global agencies, donor governments and other global health stakeholders could achieve greater impact by coordinating their efforts within a series of semi-autonomous 'policy channels' or 'workstreams'. These workstreams - including trade and agriculture, consumer health issues and workplace health promotion - could act as focal points for international cooperation, drawing in a wider range of health stakeholders within their areas of comparative advantage.
Riley, Mark R; Gerba, Charles P; Elimelech, Menachem
The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms.
Gerba Charles P
Full Text Available Abstract The U.S. National Academy of Engineering (NAE recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF. Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms.
Kantibhai Naranbhai Sonaliya
Full Text Available Background: Infertility tends to be the global challenge even in the second decade of the new millennium. Especially in developing countries like India, it is still one the most lethal social evil responsible for a big proportion of cases of psychological disturbances including suicide. Again, recently, few conditions other than communicable or Non-communicable diseases are given place among the categories of significant public health problems like Road Traffic Accidents, Burns, Poisoning, drowning and few more. But, for developing countries like India, the list is incomplete without inclusion of Infertility (there may be several others also. In public health, tuberculosis, leprosy and some other diseases are considered social diseases which produce social stigma for the patients and/or his family members.1 In same manner, Infertility is an important cause of social stigmatization since centuries for a couple suffering from, especially for woman involved. During a transitory phase of industrialization and socio-economic development, the situation is changed a minute smidgen at urban areas of India but at rural parts, sub-urban or even at urban slums (mainly among pockets of recent migrants the situation is as same as a few hundred years ago. A female of no religion, caste, social status or higher level of education are barred from some stringent mores related to infertility. Infertile females are still not allowed to take part in so many religious or social ceremonies; on the contrary, they have to face more harassment including domestic violence than their counterparts, who have given birth to the child. Due to social, psychological, economic disturbances, they are forced to take multiple sorts of treatments including religious quacks. So many infertile women are exploited physically and economically also in such weird ways of treatment to gain a pregnancy.
Radenko Maric; Branko Balj
Whereas roots of globalization are far reaching, it is primarily a modern age phenomenon. Modern business operation and the world economy are characterized by domination of multinational corporations, strong presence of the government in economy and the long-term tendency towards globalization in manufacturing, trading and consumption in the world. Containing both risks and opportunities, globalization is a problem of manifold nature. For some it means regression and falling into “neocolonial...
Greenwood, David; Smith, James; Sommerville, Ian
Cloud computing promises a radical shift in the provisioning of computing resource within enterprise. This paper: i) describes the challenges that decision-makers face when attempting to determine the feasibility of the adoption of cloud computing in their organisations; ii) illustrates a lack of existing work to address the feasibility challenges of cloud adoption in enterprise; iii) introduces the Cloud Adoption Toolkit that provides a framework to support decision-makers in identifying their concerns, and matching these concerns to appropriate tools/techniques that can be used to address them. The paper adopts a position paper methodology such that case study evidence is provided, where available, to support claims. We conclude that the Cloud Adoption Toolkit, whilst still under development, shows signs that it is a useful tool for decision-makers as it helps address the feasibility challenges of cloud adoption in enterprise.
Accounting and education are both global phenomena, and there is thus an argument that accounting education should be consistent and comparable across the globe. However, accounting, and accounting education are all socially constructed and globally they have been influenced by their historical, social, economic, political and cultural contexts.…
Full Text Available Whereas roots of globalization are far reaching, it is primarily a modern age phenomenon. Modern business operation and the world economy are characterized by domination of multinational corporations, strong presence of the government in economy and the long-term tendency towards globalization in manufacturing, trading and consumption in the world. Containing both risks and opportunities, globalization is a problem of manifold nature. For some it means regression and falling into “neocolonialism”, the others glorify it. It is logical to ask the following questions: What are the consequences of globalization for governments, nations, companies and individuals? What are the business, social and ethical issues it causes? In one word, is it possible to be ethical, to avoid and correct “bad” and keep “good” consequences of total phenomena as the globalization, and whether it is rewarding in the increasing market competition?
Garon, Julie R; Cochi, Stephen L; Orenstein, Walter A
In the United States during the 1950's, polio was on the forefront of every provider and caregiver's mind. Today, most providers in the United States have never seen a case. The Global Polio Eradication Initiative (GPEI), which began in 1988 has reduced the number of cases by over 99%. The world is closer to achieving global eradication of polio than ever before but as long as poliovirus circulates anywhere in the world, every country is vulnerable. The global community can support the polio eradication effort through continued vaccination, surveillance, enforcing travel regulations and contributing financial support, partnerships and advocacy.
Discusses the shift from rights of labor through the right to labor, to the duty to labor and the changes that have resulted. Suggests that the result is global awareness of pervasive social and economic insecurity. (Author/JOW)
Quesenberry, Amanda C.; Hemmeter, Mary Louise; Ostrosky, Michaelene M.
In this study, Head Start policies and procedures related to child guidance and addressing challenging behaviors were examined. Data were gathered from six Head Start programs in the Midwest, through interviews and document analysis. The findings provide a glimpse into how Head Start programs support children's social and emotional competence and…
Poth, Cheryl-Anne; Pinto, Dorothy; Howery, Kathy
This article describes three challenges encountered during a developmental evaluation and explains how these were addressed from the evaluators' perspective. The evaluation was conducted to support the implementation of a three-year educational technology leadership project funded by the Alberta provincial government. The developmental evaluation…
design . Our work on the NPOESS program has shown that without clear lines of authority, conflicts between satellite users hampered decisions, such as for...DEFENSE WEATHER SATELLITES DOD Faces Acquisition Challenges for Addressing Capability Needs Statement of Cristina T...Environment, Committee on Science, Space, and Technology, House of Representatives July 2016 DEFENSE WEATHER SATELLITES DOD Faces Acquisition
Coddington, Michael; Miller, Mackay; Katz, Jessica
Greening the Grid provides technical assistance to energy system planners, regulators, and grid operators to overcome challenges associated with integrating variable renewable energy into the grid. This document introduces a brief overview of common technical impacts of PV on distribution systems and operations, as well as emerging strategies for successfully addressing some of the priority issues.
Pearson, David; Walpole, Sarah; Barna, Stefi
This article explores the concept of professionalism as it relates to social change and social accountability, and expands on them in the light of global environmental changes. Professionalism in medicine includes concepts of altruism, service, professional knowledge, self-regulation and autonomy. Current dialogues around social accountability suggest that medical schools should re-orientate their strategy and desired education, research and service outcomes to the health needs of the communities they serve.This article addresses the following questions: • How do we reconcile ideas of medical professionalism with the demands of creating a more equal, just, sustainable and socially inclusive society? • What new challenges do or will we face in relation to environmental degradation, biodiversity loss, ecosystem health and climate change? • How can medical schools best teach social and environmental responsiveness within a framework of professionalism? • How do medical schools ensure that tomorrow's doctors possess the knowledge, skills and attitude to adapt to the challenges they will face in future roles?We offer ideas about why and how medical educators can change, recommendations to strengthen the teaching of professionalism and social accountability and suggestions about the contribution of an emerging concept, that of "environmental accountability".
Anthropogenic emissions of greenhouse gases, such as carbon dioxide, have led to increasing atmospheric concentrations which are at least partly responsible for the roughly 0.7% degree C global warming earth has experienced since the industrial revolution. With industrial activit...
Stephen M. Graham
Full Text Available Increasing attention is being given to the challenges of management and prevention of tuberculosis in children and adolescents. There have been a number of recent important milestones achieved at the global level to address this previously neglected disease. There is now a need to increase activities and build partnerships at the regional and national levels in order to address the wide policy-practice gaps for implementation, and to take the key steps outlined in the Roadmap for Child Tuberculosis published in 2013. In this article, we provide the rationale and suggest strategies illustrated with examples to improve diagnosis, management, outcomes and prevention for children with tuberculosis in the Asia-Pacific region, with an emphasis on the need for greatly improved recording and reporting. Effective collaboration with community engagement between the child health sector, the National Tuberculosis control Programmes, community-based services and the communities themselves are essential.
Full Text Available The development of global agricultural market has been at the forefront of professional studies. Expert opinions have quite differing views as to whether the world’s food production will be able to supply the huge demand of growing population. This scientific paper provides a general overview of global agricultural directions, including views on whether agricultural productivity increases will be able to keep with food demand increases and price trends. The scientific paper has focused on the present state of the agricultural market and on the analysis of the key factors defining the tasks of the agricultural sector in the near future, with a special attention to the case of Republic of Moldova.
Hasle, Peter; Jensen, Per Langaa
The development of globalised supply chains is a major challenge for sustainability. For several years, there has been discussion within the profession whether and how ergonomics and human factors can play a role. Based on our research, we have identified five major challenges from global supply...... sustainability. Starting from such a basis, the next step would be to find ways for the ergonomics and human factors community to create international collaboration which can impact specific global supply chains....
Full Text Available Summary Increasingly, food companies play an important role in stemming the rising burden of nutrition-related chronic diseases. Concrete actions taken by these companies include global public commitments to address food reformulation, consumer information, responsible marketing, promotion of healthy lifestyles, and public-private partnerships. These actions are reviewed together with eleven specific PepsiCo goals and commitments that address products, the marketplace, and communities at large. Interim progress on these goals and commitments are discussed as well as constraints hampering faster progress. Further disease prevention depends on increasing implementation of private-public initiatives.
Mayo, Marjorie C.
The dawn of the twenty first century has been accompanied by an upsurge of anti-capitalist campaigning, challenging the very basis of the New World Economic order. This book sets out to explore the lessons from these experiences of social mobilization. How can non-governmental organizations, community based organizations and the labor and trade union movement develop effective campaigning alliances--without becoming institutionalized and incorporated themselves? How can they balance immediate...
M. N. Dudin
Full Text Available This article overviews complex study into modern trends and challenges of development of global aluminum industry. Dynamics, structure, and segmentation of global aluminum market are discussed in terms of systematic analysis. On this basis strategic map of the industry has been plotted and five forces of competition on global aluminum market have been determined which will influence directly on functioning and development of aluminum producing companies.
Mackey, Timothy Ken; Liang, Bryan Albert
Global public health is threatened by an imbalance in health worker migration from resource-poor countries to developed countries. This "brain drain" results in health workforce shortages, health system weakening, and economic loss and waste, threatening the well-being of vulnerable populations and effectiveness of global health interventions. Current structural imbalances in resource allocation and global incentive structures have resulted in 57 countries identified by WHO as having a "critical shortage" of health workers. Yet current efforts to strengthen domestic health systems have fallen short in addressing this issue. Instead, global solutions should focus on sustainable forms of equitable resource sharing. This can be accomplished by adoption of mandatory global resource and staff-sharing programs in conjunction with implementation of state-based health services corps.
to the current debates about how these firms could assert themselves in a world of far-reaching transformation. As the title of the study suggests, this contribution is made through focusing the discussion upon production offshoring, which is currently commanding attention of so many practitioners, academics...... methodology based on multiple case studies. By applying the process perspective to the offshoring phenomenon, this study develops a framework which can be distilled into a number of propositions addressing: 1) the unfolding of offshoring process in a firm over time, 2) factors affecting the trajectories...... of the process, 3) the role of peculiarities of the society and locality from where offshoring initiatives originate, 4) strategic implications of offshoring initiatives....
Richardson, Katherine; Steffen, Will; Schellnhuber, Hans J.
negotiations is the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC), published in 2007. The IPCC report has already been instrumental in increasing both public and political awareness of the societal risks associated with unchecked emission of greenhouse gases. Since...... and environment, and the many tools and approaches available to deal effectively with the challenge of climate change. The report has been produced by a writing team comprised of members of the Scientific Steering Committee for the IARU Congress and individuals invited to give the writing team academic...... of this volume. The writing team has, in addition to presentations at the Congress, drawn upon recent publications in the scientific literature to create this synthesis. This report has been critically reviewed by representatives of the Earth System Science Partnership (ESSP), by the parallel session chairs...
Richardson, Katherine; Steffen, Will; Schellnhuber, Hans J.;
and environment, and the many tools and approaches available to deal effectively with the challenge of climate change. The report has been produced by a writing team comprised of members of the Scientific Steering Committee for the IARU Congress and individuals invited to give the writing team academic...... and geographic breadth. It is based on the 16 plenary talks given at the Congress as well as input from over 80 chairs and cochairs of the 58 parallel sessions held at the Congress. The names of the plenary speakers and the chairs and co-chairs of the parallel sessions can be found on the inside cover...... of this volume. The writing team has, in addition to presentations at the Congress, drawn upon recent publications in the scientific literature to create this synthesis. This report has been critically reviewed by representatives of the Earth System Science Partnership (ESSP), by the parallel session chairs...
Baraka, Jitihada; Rusibamayila, Asinath; Kalolella, Admirabilis; Baynes, Colin
Provider perspectives have been overlooked in efforts to address the challenges of unmet need for family planning (FP). This qualitative study was undertaken in Tanzania, using 22 key informant interviews and 4 focus group discussions. The research documents perceptions of healthcare managers and providers in a rural district on the barriers to meeting latent demand for contraception. Social-ecological theory is used to interpret the findings, illustrating how service capability is determined by the social, structural and organizational environment. Providers' efforts to address unmet need for FP services are constrained by unstable reproductive preferences, low educational attainment, and misconceptions about contraceptive side effects. Societal and organizational factors--such as gender dynamics, economic conditions, religious and cultural norms, and supply chain bottlenecks, respectively--also contribute to an adverse environment for meeting needs for care. Challenges that healthcare providers face interact and produce an effect which hinders efforts to address unmet need. Interventions to address this are not sufficient unless the supply of services is combined with systems strengthening and social engagement strategies in a way that reflects the multi-layered, social institutional problems.
Md. Motaharul Islam
Full Text Available IP based Wireless Sensor Networks (IP-WSNs are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.
Islam, Md Motaharul; Huh, Eui-Nam
IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.
Goldstein, Benjamin A; Navar, Ann Marie; Carter, Rickey E
Risk prediction plays an important role in clinical cardiology research. Traditionally, most risk models have been based on regression models. While useful and robust, these statistical methods are limited to using a small number of predictors which operate in the same way on everyone, and uniformly throughout their range. The purpose of this review is to illustrate the use of machine-learning methods for development of risk prediction models. Typically presented as black box approaches, most machine-learning methods are aimed at solving particular challenges that arise in data analysis that are not well addressed by typical regression approaches. To illustrate these challenges, as well as how different methods can address them, we consider trying to predicting mortality after diagnosis of acute myocardial infarction. We use data derived from our institution's electronic health record and abstract data on 13 regularly measured laboratory markers. We walk through different challenges that arise in modelling these data and then introduce different machine-learning approaches. Finally, we discuss general issues in the application of machine-learning methods including tuning parameters, loss functions, variable importance, and missing data. Overall, this review serves as an introduction for those working on risk modelling to approach the diffuse field of machine learning.
Robert, Nicholas; Lilenbaum, Rogerio; Hurley, Patricia
ASCO's Community Research Forum is a solution-oriented venue for community research sites to overcome barriers to conducting clinical trials. The key objectives of the Forum are to (1) convene community-based researchers to identify challenges to conducting research that ASCO can address, (2) develop solution-oriented projects to address these challenges to facilitate clinical trial participation in community research settings, and (3) shape ASCO programs and policies to support members engaged in community research. The Community Research Forum holds an annual in-person meeting that convenes physician investigators, research administrators, research nurses, and clinical research associates from community-based research programs and practices. To meet identified needs, the Community Research Forum has developed the ASCO Clinical Trial Workload Assessment Tool and the ASCO Research Program Quality Assessment Tool. Both of these tools will be available to the public in 2014. The Forum is currently exploring the concept and potential metrics of a research certification program to formally assess community-based research programs, and to identify gaps and areas to improve the program in order to meet quality standards. The Community Research Forum's website aims to serve as a go-to resource for community-based physician investigators and research staff. The Community Research Forum will continue to provide a forum for community-based researchers to network, share challenges, and develop initiatives that provide solutions and facilitate the conduct of clinical trials.
In his article, "Globalizing Compassion, Photography, and the Challenge of Terror," Ariel Dorfman reflects on the use of photography to make global violence visible and to mourn the losses caused by acts of terror. Dorfman draws on events that range from the attacks on the World Trade Center to Pinochet's dictatorship to other similar atrocities and he shows that, while these events always feel singular in the moment, they are best understood comparatively. At the core of the paper is a centr...
Martinsen, Grith; Davidsen, Claus; Bauer-Gottwein, Peter
With its diverse environment and large population, China is facing water resource challenges, both in terms of quantity and quality. The North China Plain (NCP) is one of the world’s most densely populated areas and one of the highly water stressed regions of China. It counts for 15% of the Chinese...... GDP, from both industry and agriculture. The high water demand for especially irrigation has caused decade long groundwater depletion, ecosystem deterioration and high pollution loads in the region. To alleviate the water crisis of Northern China the South-North Water Transfer Project has been...... constructed. However, the project alone cannot solve the NCP’s water crisis. A hydroeconomic optimization model has been developed for the NCP system. The model area represents the administrative area of the Hai River Commission. The challenges addressed are the spatio-temporal distribution of costs...
Abdelaziz, Ahmed E M; Leite, Gustavo B; Hallenbeck, Patrick C
In order to ensure the sustainability of algal biofuel production, a number of issues need to be addressed. Previously, we reviewed some of the questions in this area involving algal species and the important challenges of nutrient supply and how these might be met. Here, we take up issues involving harvesting and the conversion ofbiomass to biofuels. Advances in both these areas are required if these third-generation fuels are to have a sufficiently high net energy ratio and a sustainable footprint. A variety of harvesting technologies are under investigation and recent studies in this area are presented and discussed. A number of different energy uses are available for algal biomass, each with their own advantages as well as challenges in terms of efficiencies and yields. Recent advances in these areas are presented and some of the especially promising conversion processes are highlighted.
Kathi K. Beratan
Full Text Available Translating the attractive concept of collaborative adaptive management (CAM into practice has proven very difficult. The papers included in this Special Feature explore why this is true and suggest how the challenges might be addressed. This summary highlights common themes, major challenges, and implications for research and practice. Many of the included papers emphasize the central importance of collaboration and stakeholder engagement as a response to complexity and uncertainty. Collectively, the papers make the case that a lack of knowledge about how to manage the human dynamics of comanagement poses a major challenge to implementing CAM. Human activities are the primary drivers of system change in most natural resource management systems, so attention to human dynamics is essential for developing useful change hypotheses and leading indicators that can provide useful and timely feedback for adaptive management. Institutions need to evolve to support adaptive and collaborative management processes. This will require thoughtful design of CAM processes, along with commitment of sufficient time and resources. Implementation challenges should be considered as a major focus for research rather than as simply barriers to progress. More effective ways of capturing practitioners' experiential knowledge are required to improve the practice of CAM. This Special Feature suggests that the concept of a CAM practitioners' journal has promise, but realization of that promise will require careful attention to the needs of and constraints on practitioners.
competitiveness, measured in terms of scientific yield and citations, primarily affects fields where articles and citations are not the traditional outputs, such as the humanities and social sciences in general and planning-related disciplines in particular. When discussing planning, it has to be stressed out that research has a merely societal value and is not aimed at developing products that can foster economic growth or delivering scientific articles that profoundly change the theoretical perspectives. Simply put, research in planning aims at increasing the safety and welfare of people. As a consequence, planning research topics have shifted from providing scientific grounds to regional development policies, to addressing research quality and social responsibility or producing research guidelines. This article looks at the particular case of Romanian planning research based on SCImago data, in an attempt to assess whether this field is able to meet these global challenges, especially after the consistent, albeit uneven, in terms of goal and pace, application of new research policies designed after joining the European Union, which were aimed at increasing its article output and its international visibility. The findings indicate that the numerical growth of articles and publications is spectacular in Romania for most fields, and even more so within the humanities, the social sciences and planning. However, the question remains whether this impressive growth is supported by an increase in quality. We have therefore left aside matters such as the globalization of authors, topics or citations. These aspects require a more in-depth research effort.
Packer, Jasmin G.; Meyerson, Laura A.; Richardson, David M.;
Much has been done to address the challenges of biological invasions, but fundamental questions (e.g., which species invade? Which habitats are invaded? How can invasions be effectively managed?) still need to be answered before the spread and impact of alien taxa can be effectively managed. Ques...
Agrippah Kandiero; Nelson Jagero
Emerging Technologies have been put forward by many theorists and researchers in the field of education as the key to 21st century pedagogy alternative, with promise to address learning challenges and provide a platform for authentic learning. This paper reports on use of Emerging Technologies to address learning challenges and derive authentic learning in a Mathematics for Business undergraduate course at Africa University. The research was motivated by an authentic learning challenge based ...
This article serves as an overview of the various career challenges and opportunities faced by chemistry professionals in the 21st century in the global chemistry enterprise. One goal is to highlight a broad spectrum of career paths, including non-traditional careers, and to showcase examples of ch...
Reade, Carol; Todd, Anne Marie; Osland, Asbjorn; Osland, Joyce
The article presents a case study in which business leaders deal with challenging problems related to poverty, involving multiple stakeholders. This emphasizes the importance of training prospective global leaders to manage stakeholder relationships and engage in stakeholder dialogue. The authors highlight the stakeholder role played by…
Hasle, Peter; Jensen, Per Langaa
The development of globalised supply chains is a major challenge for sustainability. For several years, there has been discussion within the profession whether and how ergonomics and human factors can play a role. Based on our research, we have identified five major challenges from global supply chains especially related to the social aspects of sustainability: (1) criteria for social sustainability, (2) the role of key performance indicators in the management of supply chains, (3) the constant changes in supply chains, (4) the challenge in establishing participation, and (5) the development of agency and regulatory mechanisms. There are obviously no clear and simple solutions to these challenges. One possible avenue for progress might lie in acquiring a greater understanding of the challenges from global supply chains and developing a strategy which combines social and long-term business sustainability. Starting from such a basis, the next step would be to find ways for the ergonomics and human factors community to create international collaboration which can impact specific global supply chains.
Houseal, A.; Gallagher, R.; Fuhrmann, B.; Sanford, R.
The literature outlines many challenges faced by Student-Teacher-Scientist Partnerships (STSPs) including cultural differences between the scientific research and education communities. For example, shared vocabulary terms with dissimilar definitions can create communication problems. Other issues include accuracy in data collection, meeting the needs of a very diverse group of partners, connecting students with research science in a meaningful way, and maintaining the infrastructure necessary to develop and maintain these partnerships. Additionally, evidence, other than anecdotal, of the success of these partnerships is limited, especially as school year and research cycles are often on different schedules or have very different goals. Students, Teachers, and Rangers & Research Scientists: Investigating Systems at Mammoth Hot Springs in Yellowstone National Park (STaRRS) was an STSP developed to address some of these challenges, model some solutions within an STSP, and identify some possible outcomes for participating teachers and their students. Three strategies used to address some of these challenges that will be discussed briefly in this presentation include: (a) embedding the STSP in an already existing National Park Service environmental education program; (b) development of three types of research activities connecting teachers, students, and scientists to the research, and (c) a professional development (PD) model that included all partners in an on-going year-long process. Results from an accompanying research study will also be presented. Using a pretest-intervention-posttest design, this study revealed significant changes in attitude regarding science and scientists of participating STaRRS teachers. Student data gathered using a quasi-experimental pretest-intervention-posttest treatment and comparison group design also demonstrated significant changes in their attitudes and gains in earth science content knowledge.
Eswaran, Sharanya; Misra, Archan; La Porta, Thomas; Leung, Kin
This paper examines the practical challenges in the application of the distributed network utility maximization (NUM) framework to the problem of resource allocation and sensor device adaptation in a mission-centric wireless sensor network (WSN) environment. By providing rich (multi-modal), real-time information about a variety of (often inaccessible or hostile) operating environments, sensors such as video, acoustic and short-aperture radar enhance the situational awareness of many battlefield missions. Prior work on the applicability of the NUM framework to mission-centric WSNs has focused on tackling the challenges introduced by i) the definition of an individual mission's utility as a collective function of multiple sensor flows and ii) the dissemination of an individual sensor's data via a multicast tree to multiple consuming missions. However, the practical application and performance of this framework is influenced by several parameters internal to the framework and also by implementation-specific decisions. This is made further complex due to mobile nodes. In this paper, we use discrete-event simulations to study the effects of these parameters on the performance of the protocol in terms of speed of convergence, packet loss, and signaling overhead thereby addressing the challenges posed by wireless interference and node mobility in ad-hoc battlefield scenarios. This study provides better understanding of the issues involved in the practical adaptation of the NUM framework. It also helps identify potential avenues of improvement within the framework and protocol.
Full Text Available The year 2016 could turn out to be a turning point for global health, new political realities and global insecurities will test governance and financing mechanisms in relation to both people and planet. But most importantly political factors such as the global power shift and “the rise of the rest” will define the future of global health. A new mix of health inequity and security challenges has emerged and the 2015 humanitarian and health crises have shown the limits of existing systems. The global health as well as the humanitarian system will have to prove their capacity to respond and reform. The challenge ahead is deeply political, especially for the rising political actors. They are confronted with the consequences of a model of development that has neglected sustainability and equity, and was built on their exploitation. Some direction has been given by the path breaking international conferences in 2015. Especially the agreement on the Sustainable Development Goals (SDGs and the Paris agreement on climate change will shape action. Conceptually, we will need a different understanding of global health and its ultimate goals - the health of people can no longer be seen separate from the health of the planet and wealth measured by parameters of growth will no longer ensure health.
The year 2016 could turn out to be a turning point for global health, new political realities and global insecurities will test governance and financing mechanisms in relation to both people and planet. But most importantly political factors such as the global power shift and "the rise of the rest" will define the future of global health. A new mix of health inequity and security challenges has emerged and the 2015 humanitarian and health crises have shown the limits of existing systems. The global health as well as the humanitarian system will have to prove their capacity to respond and reform. The challenge ahead is deeply political, especially for the rising political actors. They are confronted with the consequences of a model of development that has neglected sustainability and equity, and was built on their exploitation. Some direction has been given by the path breaking international conferences in 2015. Especially the agreement on the Sustainable Development Goals (SDGs) and the Paris agreement on climate change will shape action. Conceptually, we will need a different understanding of global health and its ultimate goals - the health of people can no longer be seen separate from the health of the planet and wealth measured by parameters of growth will no longer ensure health.
Hammond, Jeffrey R.; Krishnamoorthy, Sriram; Shende, Sameer; Romero, Nichols A.; Malony, Allen D.
The use of global address space languages and one-sided communication for complex applications is gaining attention in the parallel computing community. However, lack of good evaluative methods to observe multiple levels of performance makes it difficult to isolate the cause of performance deficiencies and to understand the fundamental limitations of system and application design for future improvement. NWChem is a popular computational chemistry package which depends on the Global Arrays/ ARMCI suite for partitioned global address space functionality to deliver high-end molecular modeling capabilities. A workload characterization methodology was developed to support NWChem performance engineering on large-scale parallel platforms. The research involved both the integration of performance instrumentation and measurement in the NWChem software, as well as the analysis of one-sided communication performance in the context of NWChem workloads. Scaling studies were conducted for NWChem on Blue Gene/P and on two large-scale clusters using different generation Infiniband interconnects and x86 processors. The performance analysis and results show how subtle changes in the runtime parameters related to the communication subsystem could have significant impact on performance behavior. The tool has successfully identified several algorithmic bottlenecks which are already being tackled by computational chemists to improve NWChem performance.
Obrenović Zoran G.
Full Text Available This project draft discusses the issues facing a nation state in the dynamic processes of globalization. First, the term globalization is tentatively defined as a decentralized process of condensation and homogenization of space and time. Then, the ambivalent structure of the globalization discourse, i.e. its semantic and pragmatic dimensions, are shown. The neo-liberal viewpoint is explored of the erosion and weakening of the nation state within the global capitalist power, both in terms of its (state's traditional functions, and in terms of its internal and external sovereignty. Against the neo-liberal thesis about the decline of the nation state many empirical arguments have been offered. Some of these are presented in this text. The main point of this argumentation consists in a general view that the decline of the nation state is strongly linked with the process of globalization. In view of the critical argumentation included in the paper, it is argued that in the environment of global processes only the societies which have a strong state behind them have a chance to succeed. Politics, not economy, still dominates international relations. Emphasis on state politics opens a new perspective in discussing the process of globalization. Current globalization processes cannot be judged accurately unless geopolitical interests and the changing balance of world power are understood. Finally, the paper points to the ideological nature of the neo-liberal discourse of globalization, questioning another basic assumption of the latter, namely, the idea that the process of globalization is at the same time a process of emancipation. By challenging the positing of a necessary link between globalization and emancipation we formulate a position that allows for a normative critique of current processes.
Marc A. Rosen
Full Text Available Sustainability is a critically important goal for human activity and development, particularly in the area of energy. Energy resources are critical for economic development and living standards, but their use causes significant environmental impacts. Given the pervasiveness of energy use, energy sustainability is a key to addressing environmental, economic and societal challenges. To achieve energy sustainability, many factors that need to be including harnessing sustainable energy sources, utilizing sustainable energy carriers, increasing efficiency, reducing environmental impact and improving socioeconomic acceptability (e.g., community involvement, affordability, equity and land use. To demonstrate the factors and their importance to energy sustainability, the Red-Mediterranean-Dead Seas Canal Project is considered as a case study. Conclusions are provided related both to steps for energy sustainability.
Colpitts, Che C; Baumert, Thomas F
Chronic hepatitis C is a major cause of chronic liver disease, including liver cirrhosis and hepatocellular carcinoma. The development of direct-acting antivirals (DAAs) revolutionized hepatitis C virus (HCV) treatment by offering genuine prospects for the first comprehensive cure of a chronic viral infection in humans. While antiviral resistance is a significant limitation for interferon-based therapies, resistance and treatment failure still appear to be present in a small fraction of patients even in state-of-the-art DAA combination therapies. Therefore, treatment failure and resistance still remain a clinical challenge for the management of patients not responding to DAAs. In this special issue of Viruses on HCV drug resistance, mechanisms of antiviral resistance for different classes of antiviral drugs are described. Furthermore, the detection and monitoring of resistance in clinical practice, the clinical impact of resistance in different patient groups and strategies to prevent and address resistance and treatment failure using complementary antiviral strategies are reviewed.
Che C. Colpitts
Full Text Available Chronic hepatitis C is a major cause of chronic liver disease, including liver cirrhosis and hepatocellular carcinoma. The development of direct-acting antivirals (DAAs revolutionized hepatitis C virus (HCV treatment by offering genuine prospects for the first comprehensive cure of a chronic viral infection in humans. While antiviral resistance is a significant limitation for interferon-based therapies, resistance and treatment failure still appear to be present in a small fraction of patients even in state-of-the-art DAA combination therapies. Therefore, treatment failure and resistance still remain a clinical challenge for the management of patients not responding to DAAs. In this special issue of Viruses on HCV drug resistance, mechanisms of antiviral resistance for different classes of antiviral drugs are described. Furthermore, the detection and monitoring of resistance in clinical practice, the clinical impact of resistance in different patient groups and strategies to prevent and address resistance and treatment failure using complementary antiviral strategies are reviewed.
Pasian, Fabio; Genova, Francoise; Lamanna, Giovanni; Serjeant, Stephen; Szomoru, Arpad; van der Meer, Rob
The large infrastructure projects for the next decade will allow a new quantum leap in terms of new possible science. ESFRI, the European Strategy Forum on Research Infrastructures, a strategic initiative to develop the scientific integration of Europe, has identified four facilities (SKA, CTA, KM3Net and E-ELT) deserving priority in support. The ASTERICS project aims to address the cross-cutting synergies and common challenges shared by the various Astronomy ESFRI and other world-class facilities. The project (22 partners across Europe) is funded by the EU Horizon 2020 programme with 15 MEuro in 4 years. It brings together for the first time the astronomy, astrophysics and particle astrophysics communities, in addition to other related research infrastructures.
Full Text Available In this paper, we analyze the effect of globalization in general and from the viewpoint of the small and medium sized companies in the Republic of Macedonia, as a typical developing economy. Our survey of 100 managers and business owners from small and medium sized enterprises indicates that they tend to perceive the globalization with more conservative glasses as negative, or at the best, as a neutral phenomenon to their overall business prospects. However, to harvest the apparent opportunities of the globalization and to achieve the desired internationalization of their businesses, they call for intensive regional cooperation seeing it as a gateway to much harsher realms of the globalized market. The literature review and the examples from some other countries support these conservative standing of our managers and offer practical explanations why the approach towards the globalization is conservative and often even negative. Small business is important provider of new jobs, ideas and business concepts. However, with the opening of the global market it is a constant pursue for customers all around the world, having to meet their diverse and rapidly changing needs and facing extremely shortened delivery terms and product lifecycles. Many small companies, particularly from the developing countries are not adequately prepared to face the reality of this challenge. On the other hand, the big multinational companies receive more than hefty incentives to invest into the developing countries and that creates additional negative sentiments towards the globalization among the local companies.
Gow, Neil A. R.; Netea, Mihai G.
Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV. These statistics evidence fungal infections as a major threat to human health and a major burden to healthcare budgets worldwide. Those patients who are at greatest risk of life-threatening fungal infections include those who have weakened immunity or have suffered trauma or other predisposing infections such as HIV. To address these global threats to human health, more research is urgently needed to understand the immunopathology of fungal disease and human disease susceptibility in order to augment the advances being made in fungal diagnostics and drug development. Here, we highlight some recent advances in basic research in medical mycology and fungal immunology that are beginning to inform clinical decisions and options for personalized medicine, vaccine development and adjunct immunotherapies. This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’. PMID:28080988
Dugas, Tammy R; Lomnicki, Slawomir; Cormier, Stephania A; Dellinger, Barry; Reams, Margaret
Airborne fine and ultrafine particulate matter (PM) are often generated through widely-used thermal processes such as the combustion of fuels or the thermal decomposition of waste. Residents near Superfund sites are exposed to PM through the inhalation of windblown dust, ingestion of soil and sediments, and inhalation of emissions from the on-site thermal treatment of contaminated soils. Epidemiological evidence supports a link between exposure to airborne PM and an increased risk of cardiovascular and pulmonary diseases. It is well-known that during combustion processes, incomplete combustion can lead to the production of organic pollutants that can adsorb to the surface of PM. Recent studies have demonstrated that their interaction with metal centers can lead to the generation of a surface stabilized metal-radical complex capable of redox cycling to produce ROS. Moreover, these free radicals can persist in the environment, hence their designation as Environmentally Persistent Free Radicals (EPFR). EPFR has been demonstrated in both ambient air PM2.5 (diameter < 2.5 µm) and in PM from a variety of combustion sources. Thus, low-temperature, thermal treatment of soils can potentially increase the concentration of EPFR in areas in and around Superfund sites. In this review, we will outline the evidence to date supporting EPFR formation and its environmental significance. Furthermore, we will address the lack of methodologies for specifically addressing its risk assessment and challenges associated with regulating this new, emerging contaminant.
Bosomworth, Karyn; Owen, Christine; Curnin, Steven
The mounting frequency and intensity of natural hazards, alongside growing interdependencies between social-technical and ecological systems, are placing increased pressure on emergency management. This is particularly true at the strategic level of emergency management, which involves planning for and managing non-routine, high-consequence events. Drawing on the literature, a survey, and interviews and workshops with Australia's senior emergency managers, this paper presents an analysis of five core challenges that these pressures are creating for strategic-level emergency management. It argues that emphasising 'emergency management' as a primary adaptation strategy is a retrograde step that ignores the importance of addressing socio-political drivers of vulnerabilities. Three key suggestions are presented that could assist the country's strategic-level emergency management in tackling these challenges: (i) reframe emergency management as a component of disaster risk reduction rather than them being one and the same; (ii) adopt a network governance approach; and (iii) further develop the capacities of strategic-level emergency managers.
Smith, B R
Most major cities worldwide face urban water management challenges relating to drinking supply, stormwater and wastewater treatment, and ecological preservation. In light of climate change and finite natural resources, addressing these challenges in sustainable ways will require innovative solutions arising from interdisciplinary collaboration. This article summarizes five major urban water management strategies that bridge the fields of engineering, ecology, landscape architecture, and urban planning. A conceptual implementation of these strategies is demonstrated through a design for a small constructed wetland treatment system in San Francisco, California. The proposed decentralized system described in this article consists of a detention basin, vegetated and open free water surface wetlands, and ultraviolet disinfection. In wet weather, the system would detain and treat combined sewer discharges (CSD), and in dry weather it would treat residential greywater for toilet flushing and irrigation in a nearby neighborhood. It is designed to adapt over time to changing climatic conditions and treatment demands. Importantly, this proposal demonstrates how constructed wetland engineers can incorporate multiple benefits into their systems, offering a vision of how wastewater infrastructure can be an attractive community, educational, recreational, and habitat amenity through the integration of engineering, ecology, and landscape design.
Munro, Ian C; Haighton, Lois A; Lynch, Barry S; Tafazoli, Shahrzad
The risk assessment of migration products resulting from packaging material has and continues to pose a difficult challenge. In most jurisdictions, there are regulatory requirements for the approval or notification of food contact substances that will be used in packaging. These processes generally require risk assessment to ensure safety concerns are addressed. The science of assessing food contact materials was instrumental in the development of the concept of Threshold of Regulation and the Threshold of Toxicological Concern procedures. While the risk assessment process is in place, the technology of food packaging continues to evolve to include new initiatives, such as the inclusion of antimicrobial substances or enzyme systems to prevent spoilage, use of plastic packaging intended to remain on foods as they are being cooked, to the introduction of more rigid, stable and reusable materials, and active packaging to extend the shelf-life of food. Each new technology brings with it the potential for exposure to new and possibly novel substances as a result of migration, interaction with other chemical packaging components, or, in the case of plastics now used in direct cooking of products, degradation products formed during heating. Furthermore, the presence of trace levels of certain chemicals from packaging that were once accepted as being of low risk based on traditional toxicology studies are being challenged on the basis of reports of adverse effects, particularly with respect to endocrine disruption, alleged to occur at very low doses. A recent example is the case of bisphenol A. The way forward to assess new packaging technologies and reports of very low dose effects in non-standard studies of food contact substances is likely to remain controversial. However, the risk assessment paradigm is sufficiently robust and flexible to be adapted to meet these challenges. The use of the Threshold of Regulation and the Threshold of Toxicological Concern concepts may
Trigg, M. A.; Birch, C. E.; Neal, J. C.; Bates, P. D.; Smith, A.; Sampson, C. C.; Yamazaki, D.; Hirabayashi, Y.; Pappenberger, F.; Dutra, E.; Ward, P. J.; Winsemius, H. C.; Salamon, P.; Dottori, F.; Rudari, R.; Kappes, M. S.; Simpson, A. L.; Hadzilacos, G.; Fewtrell, T. J.
Quantifying flood hazard is an essential component of resilience planning, emergency response, and mitigation, including insurance. Traditionally undertaken at catchment and national scales, recently, efforts have intensified to estimate flood risk globally to better allow consistent and equitable decision making. Global flood hazard models are now a practical reality, thanks to improvements in numerical algorithms, global datasets, computing power, and coupled modelling frameworks. Outputs of these models are vital for consistent quantification of global flood risk and in projecting the impacts of climate change. However, the urgency of these tasks means that outputs are being used as soon as they are made available and before such methods have been adequately tested. To address this, we compare multi-probability flood hazard maps for Africa from six global models and show wide variation in their flood hazard, economic loss and exposed population estimates, which has serious implications for model credibility. While there is around 30%-40% agreement in flood extent, our results show that even at continental scales, there are significant differences in hazard magnitude and spatial pattern between models, notably in deltas, arid/semi-arid zones and wetlands. This study is an important step towards a better understanding of modelling global flood hazard, which is urgently required for both current risk and climate change projections.
Gupta, Rajesh; Patel, Rajan; Murty, Naganand; Panicker, Rahul; Chen, Jane
Relative to drugs, diagnostics, and vaccines, efforts to develop other global health technologies, such as medical devices, are limited and often focus on the short-term goal of prototype development instead of the long-term goal of a sustainable business model. To develop a medical device to address neonatal hypothermia for use in resource-limited settings, we turned to principles of design theory: (1) define the problem with consideration of appropriate integration into relevant health policies, (2) identify the users of the technology and the scenarios in which the technology would be used, and (3) use a highly iterative product design and development process that incorporates the perspective of the user of the technology at the outset and addresses scalability. In contrast to our initial idea, to create a single device, the process guided us to create two separate devices, both strikingly different from current solutions. We offer insights from our initial experience that may be helpful to others engaging in global health technology development.
Kuemmerle, Tobias; Erb, Karlheinz; Meyfroidt, Patrick;
we lack appropriate datasets to assess land use intensity across broad geographic extents. Here, we review the state of the art regarding approaches for mapping land use intensity and provide a comprehensive overview of available global-scale datasets on land use intensity. We also outline major...... challenges and opportunities for mapping land use intensity for cropland, grazing, and forestry systems, and identify key issues for future research. © 2013 Elsevier B.V. All rights reserved....
The environment is an established domain of nursing knowledge, but some authors argue that the traditional perspective is too narrowly focused on the immediate environment to appreciate the relevance of the global environment. This article explores how human activities are bringing about global changes through their impact on biogeochemical cycles, land use and mobility of organisms, altering biodiversity and climate, and ultimately compromising the ecosystems services that sustain our planet. The consequences of global change for population health are examined, including the emergence of drug-resistant diseases, and the implications of climate warming and pollution for health. Addressing these issues presents a considerable challenge for nursing at all levels, in promoting sustainable policies, integrating environmental considerations into clinical practice, and in the nursing role as health educators. The greatest challenge is to education, to raise awareness of the relevance and importance of the global environment to health, and to empower nurses with sufficient understanding of the issues to apply them to practice, participate in debate and contribute to policy-making that aims to reduce the burden of global changes. The extent to which the profession is prepared to diversify in response to these challenges is discussed.
. Furthermore, the stability and presence of certain minerals on planetary surfaces and the potential habitability of microorganisms under various planetary environmental conditions can be studied using our apparatus. Therefore, these simulation chambers can address multiple different challenging and multidisciplinary astrobiological studies.
Clark, Toni A.
In our day to day lives, the availability of light, with which to see our environment, is often taken for granted. The designers of land based lighting systems use sunlight and artificial light as their toolset. The availability of power, quantity of light sources, and variety of design options are often unlimited. The accessibility of most land based lighting systems makes it easy for the architect and engineer to verify and validate their design ideas. Failures with an implementation, while sometimes costly, can easily be addressed by renovation. Consider now, an architectural facility orbiting in space, 260 miles above the surface of the earth. This human rated architectural facility, the International Space Station (ISS) must maintain operations every day, including life support and appropriate human comforts without fail. The facility must also handle logistics of regular shipments of cargo, including new passengers. The ISS requires accommodations necessary for human control of machine systems. Additionally, the ISS is a research facility and supports investigations performed inside and outside its livable volume. Finally, the facility must support remote operations and observations by ground controllers. All of these architectural needs require a functional, safe, and even an aesthetic lighting environment. At Johnson Space Center, our Habitability and Human Factors team assists our diverse customers with their lighting environment challenges, via physical test and computer based analysis. Because of the complexity of ISS operational environment, our team has learned and developed processes that help ISS operate safely. Because of the dynamic exterior lighting environment, uses computational modeling to predict the lighting environment. The ISS' orbit exposes it to a sunrise every 90 minutes, causing work surfaces to quickly change from direct sunlight to earthshine to total darkness. Proper planning of vehicle approaches, robotics operations, and crewed
Full Text Available The application of fallout radionuclides in soil erosion investigations and related sediment budget studies has provided a widely used tool for improving understanding of soil erosion and sediment transfer processes. However, most studies using fallout radionuclides undertaken to date have focussed on small areas. This focus on small areas reflects both the issues addressed and practical constraints associated with sample collection and analysis. Increasing acceptance of the important role of fine sediment in degrading aquatic habitats and in the transfer and fate of nutrients and contaminants within terrestrial and fluvial systems has emphasised the need to consider larger areas and the catchment or regional scale. The need to upscale existing approaches to the use of fallout radionuclides to larger areas represents an important challenge. This contribution provides a brief review of existing and potential approaches to upscaling the use of fallout radionuclides and presents two examples where such approaches have been successfully applied. These involve a national scale assessment of soil erosion rates in England and Wales based on 137Cs measurements and an investigation of the sediment budgets of three small/intermediate-size catchments in southern Italy.
Sturrock, R. N.
The health of the earths forests and urban green spaces is increasingly challenged by the outcomes of human activities, including global climate change. As climate changes, the role and impact of diseases on trees in both forest ecosystems and in urban settings will also change. Knowledge of relationships between climate variables and diseases affecting forest and urban trees is reviewed, with specific emphasis on those affecting foliage, shoots, and stems. Evidence that forest diseases are already responding to the earths changing climate is examined (e.g., Dothistroma needle blight in northern British Columbia) as are predicted scenarios for future changes in impact on forests by other tree diseases. Outbreaks of tree diseases caused by native and alien pathogens are predicted to become more frequent and intense this and other general predictions about the effects of climate change on forest and tree diseases are discussed. Despite the uncertainty that accompanies such predictions it is imperative that researchers, forest and urban tree managers, and policy makers work together to develop and implement management strategies that enhance the resilience of the worlds forests and urbanized trees. Strategies discussed include monitoring, forecasting, planning, and mitigation. (Author) 60 refs.
Feijo, Luiz P.; Burton, Gareth C. [American Bureau of Shipping (ABS), Rio de Janeiro, RJ (Brazil)
As the offshore industry continues to develop and move into increasingly deeper waters, technological boundaries are being pushed to new limits. Along with these advances, the design, fabrication and installation of deepwater oil and gas projects has become an increasingly global endeavor. After providing an overview of the history and role of Classification Societies, this paper reviews the challenges of securing classification and regulatory approval in a global environment. Operational, procedural and technological changes which one Classification Society; the American Bureau of Shipping, known as ABS, has implemented to address these challenges are presented. The result of the changes has been a more customized service aiming at faster and more streamlined classification approval process. (author)
Bundas, David J.; O'Neill, Deborah; Rhee, Michael; Feild, Thomas; Meadows, Gary; Patterson, Peter
The Global Precipitation Measurement (GPM) Mission is a collaboration between the National Aeronautics and Space Administration (NASA) and the Japanese Aerospace Exploration Agency (JAXA), and other US and international partners, with the goal of monitoring the diurnal and seasonal variations in precipitation over the surface of the earth. These measurements will be used to improve current climate models and weather forecasting, and enable improved storm and flood warnings. This paper gives an overview of the mission architecture and addresses the status of some key trade studies, including the geolocation budgeting, design considerations for spacecraft charging, and design issues related to the mitigation of orbital debris.
Frédéric Biemar; Margaret Foti
The last ten years have seen remarkable progress in cancer research. However, despite significant breakthroughs in the understanding, prevention, and treatment of cancer, the disease continues to affect millions of people worldwide. Cancer’s complexity compounded with ifnancial, policy and regulatory roadblocks has slowed the rate of progress being made against cancer. In this paper, we review a few of the most recent breakthroughs that are fueling medical advances and bringing new hope for patients affected by this devastating disease. We also address the challenges facing us and the opportunities to accelerate future progress against cancer. The efforts of the American Association for Cancer Research (AACR) to address the cancer burden already extend beyond the borders of the United States of America. hTe AACR is committed to increasing its efforts to stem the tide of cancer worldwide by promoting innovative programs, strategies, and initiatives for cancer researchers and all those engaged in cancer-related biomedical sciences around the world.
Rajasimha, Harsha Karur; Shirol, Prasannakumar Basayya; Ramamoorthy, Preveen; Hegde, Madhuri; Barde, Sangeeta; Chandru, Vijay; Ravinandan, M E; Ramchandran, Ramani; Haldar, Kasturi; Lin, Jimmy C; Babar, Imran A; Girisha, Katta M; Srinivasan, Sudha; Navaneetham, Duraiswamy; Battu, Rajani; Devarakonda, Rajashree; Kini, Usha; Vijayachandra, Kinnimulki; Verma, Ishwar C
In order to address the unmet needs and create opportunities that benefit patients with rare disease in India, a group of volunteers created a not-for-profit organization named Organization for Rare Diseases India (ORDI; www.ordindia.org). ORDI plans to represent the collective voice and advocate the needs of patients with rare diseases and other stakeholders in India. The ORDI team members come from diverse backgrounds such as genetics, molecular diagnostics, drug development, bioinformatics, communications, information technology, patient advocacy and public service. ORDI builds on the lessons learned from numerous similar organizations in the USA, European Union and disease-specific rare disease foundations in India. In this review, we provide a background on the landscape of rare diseases and the organizations that are active in this area globally and in India. We discuss the unique challenges in tackling rare diseases in India, and highlight the unmet needs of the key stakeholders of rare diseases. Finally, we define the vision, mission, goals and objectives of ORDI, identify the key developments in the health care context in India and welcome community feedback and comments on our approach.
Hantson, Stijn; Arneth, Almut; Harrison, Sandy P.; Kelley, Douglas I.; Prentice, I. Colin; Rabin, Sam S.; Archibald, Sally; Mouillot, Florent; Arnold, Steve R.; Artaxo, Paulo; Bachelet, Dominique; Ciais, Philippe; Forrest, Matthew; Friedlingstein, Pierre; Hickler, Thomas; Kaplan, Jed O.; Kloster, Silvia; Knorr, Wolfgang; Lasslop, Gitta; Li, Fang; Mangeon, Stephane; Melton, Joe R.; Meyn, Andrea; Sitch, Stephen; Spessa, Allan; van der Werf, Guido R.; Voulgarakis, Apostolos; Yue, Chao
Biomass burning impacts vegetation dynamics, biogeochemical cycling, atmospheric chemistry, and climate, with sometimes deleterious socio-economic impacts. Under future climate projections it is often expected that the risk of wildfires will increase. Our ability to predict the magnitude and geographic pattern of future fire impacts rests on our ability to model fire regimes, using either well-founded empirical relationships or process-based models with good predictive skill. While a large variety of models exist today, it is still unclear which type of model or degree of complexity is required to model fire adequately at regional to global scales. This is the central question underpinning the creation of the Fire Model Intercomparison Project (FireMIP), an international initiative to compare and evaluate existing global fire models against benchmark data sets for present-day and historical conditions. In this paper we review how fires have been represented in fire-enabled dynamic global vegetation models (DGVMs) and give an overview of the current state of the art in fire-regime modelling. We indicate which challenges still remain in global fire modelling and stress the need for a comprehensive model evaluation and outline what lessons may be learned from FireMIP.
Lee, Kelley; Brumme, Zabrina L
While there has been wide-ranging commitment to the One Health approach, its operationalisation has so far proven challenging. One Health calls upon the human, animal and environmental health sectors to cross professional, disciplinary and institutional boundaries, and to work in a more integrated fashion. At the global level, this paper argues that this vision is hindered by dysfunctions characterising current forms of global health governance (GHG), namely institutional proliferation, fragmentation, competition for scarce resources, lack of an overarching authority, and donor-driven vertical programmes. This has contributed, in part, to shortcomings in how One Health has been articulated to date. An agreed operational definition of One Health among key global institutions, efforts to build One Health institutions from the ground up, comparative case studies of what works or does not work institutionally, and high-level global support for research, training and career opportunities would all help to enable One Health to help remedy, and not be subsumed by, existing dysfunctions in GHG.
Brauch, Hans Guenter [Freie Univ. Berlin (Germany). Dept. of Political and Social Sciences; UNU-EHS, Bonn (DE). College of Associated Scientists and Advisors (CASA); Oswald Spring, Ursula [National Univ. of Mexico, Cuernavaca (MX). Regional Multidisciplinary Research Centre (CRIM); Mesjasz, Czeslaw [Cracow Univ. of Exonomics (Poland). Faculty of Management; Grin, John [Amsterdam Univ. (Netherlands). Dept. of Political Science; Dutch Knowledge network for Systems Innovations and Transitions (KSI), Amsterdam (Netherlands); Kameri-Mbote, Patricia [Strathmore Univ., Nairobi (Kenya). Dept. of Law; International Environmental Law Research Centre, Nairobi (Kenya); Chourou, Bechir [Univ. of Tunis-Carthage, Hammam-Chatt (Tunisia); Dunay, Pal [Geneva Centre for Security Policy (Switzerland). International Training Course in Security Policy; Birkmann, Joern (eds.) [United Nations Univ. (UNU), Bonn (DE). Inst. for Environment and Human Security (EHS)
This policy-focused Global Environmental and Human Security Handbook for the Anthropo-cene (GEHSHA) addresses new security threats, challenges, vulnerabilities and risks posed by global environmental change and disasters. In 6 forewords, 5 preface essays 95 peer reviewed chapcountries analyse in 10 parts concepts of military and political hard security and economic, social, environmental soft security with a regional focus on the Near East, North and Sub-Sahara Africa and Asia and on hazards in urban centres. The major focus is on coping with global environmental change: climate change, desertification, water, food and health and with hazards and strategies on social vulnerability and resilience building and scientific, international, regional and national political strategies, policies and measures including early warning of conflicts and hazards. The book proposes a political geo-ecology and discusses a 'Fourth Green Revolution' for the Anthropocene era of earth history. (orig.)
PUSCH, R; NAKANO, M
High Level Radioactive Waste (HLW) Disposal, A Global Challenge presents the most recent information on proposed methods of disposal for the most dangerous radioactive waste and for assessing their function from short- and long-term perspectives. It discusses new aspects of the disposal of such waste, especially HLW.The book is unique in the literature in making it clear that, due to tectonics and long-term changes in rock structure, rock can serve only as a ""mechanical support to the chemical apparatus"" and that effective containment of hazardous elements can only be managed by properly des
Petersen, R. A.; Dworak, R.
The challenges of transforming data from the next generation of satellites into information and products for the weather and science purposes presents a major challenge to both the research and applications communities. This will be especially difficult over land, where the process of integrating observations from multiple instruments and platforms in real time is complicated by the influence of the land surface on the observations themselves. In addition, effective merging of the mixture of time-continuous GEO and less frequent but higher spectral resolution LEO observations with other new surface-based observations will be essential and require new product processing strategies. The material shown in this presentation will begin to address some of these issues. It will describe results of efforts to inter-calibrate moisture products derived from existing GEO and LEO data sets over land designed 1) to identify and remove biases from the GOES moisture retrievals, 2) to determine the seasonally varying information content of the GOES relative to NWP model 'first guess' fields, 3) to determine the similarities and differences in error structures between GOES and AIRS retrievals, and 4) to determine the vertical structure of the errors in both systems. For example, comparisons have been made between GOES Total Precipitable Water (TPW) using the Li retrieval system (GOES-Li) and data from Raman Lidar (RL), Microwave Radiometer (MWR) and surface-based GPS-Met systems at the ARM CART site. The test showed for using one year of derived TPW products, the NWP model first guess (GFS) and GOES-Li products are wetter, however the GOES-Li beats the GFS in the warm season, especially in August when the NWP precipitation skill is least. During the warm season GOES-Li is noticeably better than GFS (which was too wet) during daytime. In addition, the GPS-Met data are best during the daytime, while the Ramon Lidar performs best at night. AIRS products were also evaluated for several
Smith, P., II
Data capture is an important process in the research lifecycle. Complete descriptive and representative information of the data or database is necessary during data collection whether in the field or in the research lab. The National Science Foundation's (NSF) Public Access Plan (2015) mandates the need for federally funded projects to make their research data more openly available. Developing, implementing, and integrating metadata workflows into to the research process of the data lifecycle facilitates improved data access while also addressing interoperability challenges for the geosciences such as data description and representation. Lack of metadata or data curation can contribute to (1) semantic, (2) ontology, and (3) data integration issues within and across disciplinary domains and projects. Some researchers of EarthCube funded projects have identified these issues as gaps. These gaps can contribute to interoperability data access, discovery, and integration issues between domain-specific and general data repositories. Academic Research Libraries have expertise in providing long-term discovery and access through the use of metadata standards and provision of access to research data, datasets, and publications via institutional repositories. Metadata crosswalks, open archival information systems (OAIS), trusted-repositories, data seal of approval, persistent URL, linking data, objects, resources, and publications in institutional repositories and digital content management systems are common components in the library discipline. These components contribute to a library perspective on data access and discovery that can benefit the geosciences. The USGS Community for Data Integration (CDI) has developed the Science Support Framework (SSF) for data management and integration within its community of practice for contribution to improved understanding of the Earth's physical and biological systems. The USGS CDI SSF can be used as a reference model to map to Earth
Full Text Available The population of Dublin City and its suburbs currently stands at 1.3 million and is projected to reach 2.1 million by 2022. There is pressure on its water supply system (inadequate catchment sources, ageing infrastructure including treatment facilities, and distribution network with little or no spare capacity despite Ireland's relatively high rainfall that is well distributed throughout the year; albeit the greatest rainfall occurs in the west and southwest and at some remove from Dublin. The current governance approach to addressing the projected water supply deficit relies heavily on a combination of identifying new supply sources to secure the long-term water supply needs of the city together with an intense drive toward achieving "demand-side" reduced usage and conservation targets in accordance with EU benchmarks for various individual and sectoral users. This potentially emerging crisis of water scarcity in Dublin, with drivers including population growth, greater industrial and institutional demands, migration, and climate change, has generated one of the most significant public water works projects proposed in Irish history, which is to abstract raw water from the Shannon River Basin in the midland region and, following treatment, pump it to a storage reservoir in a cut-away bog before piping to the Greater Dublin Area. The preparations for this scheme have brought to the forefront some longstanding Irish water resources governance issues and challenges. This provides a unique opportunity and imperative at this time to take a more comprehensive look at the decision-making process in this regard, one done in the context of new European and national policies requiring incorporation of integrated planning to sustain ecosystem services, water resources management, water services management, and flood defense principles, and one taking account of the current unprecedented state of flux in which water resources management institutions in
Zahedi, Mansooreh; Shahin, Mojtaba; Babar, Muhammad Ali
Context: Global Software Development (GSD) presents significant challenges to share and understand knowledge required for developing software. Organizations are expected to implement appropriate practices to address knowledge-sharing challenges in GSD. With the growing literature on GSD and its...... the data extracted from the reviewed primary studies. Results: Our findings revealed that knowledge sharing challenges and practices in GSD could be classi- fied in 6 main themes: management, team structure, work processes/practices, team cognition, social attributes and technology. In regard to contextual...... settings, we found empirical studies were mainly con- ducted in an offshore outsourcing collaboration model distributed between two sites. Most of the studied organizations were large enterprises. Many of the studies did not report any information for several con- textual attributes that made it difficult...
Beran, David; Ewen, Margaret; Laing, Richard
Substantial attention has been given to the issue of access to medicines for communicable diseases; however, access to essential medicines for diabetes, especially insulin, has had insufficient focus. Although insulin was discovered in 1921, the drug is unattainable to many globally, and this Review aims to highlight the range and complexity of factors that contribute to this unattainability. Manufacturers' selling prices of various insulin formulations and presentations, duties, taxes, mark-ups, and other supply chain costs affect the price of insulin and hence the drug's affordability to health systems and individuals. Unlike drugs for HIV and AIDS, the production of generic or biosimilar insulin has not had an effect on the overall market. Other factors contributing to poor availability of insulin include its quantification at the national level, in-country distribution, and determination of needs at lower levels of the health system. Although insulin is essential for the survival of people with type 1 diabetes and is needed for improved management of diabetes for some people with type 2 diabetes, very little has been done globally to address the issue of access, despite the UN's political commitment to address non-communicable diseases and ensure universal access to drugs for these disorders.
Bates, Alison Waterbury
Society is facing a pressing need to reduce greenhouse gas emissions to limit anthropogenic climate change, which has far reaching implications for humans and the environment. Transforming the energy infrastructure to carbon-free sources is one solution to curb greenhouse gas emissions, but this transformation has been slow to materialize in many places, such as the United States (U.S.). Offshore wind energy is one of the most promising renewable energy sources available, which can be deployed in large-scale developments in many parts of the world. Yet, offshore wind has faced many challenges, which are more social and regulatory than technical. This dissertation addresses social and regulatory issues surrounding offshore wind development through three stand-alone essays, which, in combination, address a decision-making framework of where to locate offshore wind turbines, by minimizing effects on people and wildlife. The challenges to offshore wind that are addressed by this dissertation include (1) understanding underlying factors that drive support for or opposition to offshore wind energy; (2) conflict with existing ocean uses and users; and (3) public concern and regulatory processes related to wildlife impacts. The first paper identifies unique factors that drive public opinion of proposed offshore wind projects in nearby coastal communities. Wind energy development on land has faced local opposition for reasons such as effects on cultural landscapes and wildlife, which can be instrumental in whether or not and the speed with which a project moves ahead toward completion. Factors leading to support for, or opposition to, offshore wind energy are not well known, particularly for developments that are near-shore and in-view of coastal communities. Results are presented from a survey of 699 residents (35.5% response rate) completed in 2013 in greater Atlantic City, New Jersey and coastal Delaware, United States, where near-shore wind demonstration projects had
Terblanche, D. E.; Tarasova, O. A.
The Global Atmosphere Watch Programme, one of the tree research Programmes of the World Meteorological Organization (WMO/GAW) is the only existing long-term international global programme that coordinates observations and analysis of atmospheric composition changes. The GAW Programme builds on a partnership of more than 100 countries. Within its 25 years of existence WMO/GAW has matured to the system that provides reliable long-term high quality observations in support of international policy making. WMO/GAW includes globally coordinated observational network, complemented by a comprehensive quality assurance system and capacity development. In spite of the fact that GAW has embraced the IGACO strategy (Integrated Global Atmospheric Chemistry Observations), the programme in its current form still has a strong observational bias. Future development of WMO/GAW requires the further evolution of the programme concept toward "science for services". New challenges call for the changes in the GAW station requirements and data managements, for new approaches to collaboration with the contributing networks and better involvement of the modelling community. The programme structure is evolving to streamline better to user requirements with the move from precipitation chemistry to total deposition and from near-real-time data delivery to applications (modeling) requiring such data delivery. The updated concept of GAW will include more cross-cutting applications. A new category of local station is introduced to help with the verification of some applications including those related to urban areas and the impacts of urban complexes regionally and globally. The evolution of the GAW Programme towards user driven cross-cutting applications provides a new opportunity to the National Meteorological and Hydrological Services in partnership with other science - based institutions to increase their relevance to society.
Three areas of far reaching change that will affect the future of the energy industry are identified - geopolitical changes, such as the collapse of communist regimes in Eastern Europe and the Soviet Union, the relative decline of economic importance of the USA and the stimulus of European Community programmes; changes and difficulties in the international economy such as disagreement over trade and foreign direct investment; and thirdly, changing attitudes towards man's impact on the natural environment. These changes suggest two different images of the future, one called 'global mercantilism' and the other 'sustainable change'. In the first, the main global challenge is to deal with decline in the hegemonic position of the USA and Japan and the instability in international markets - the energy industry here faces new rules for business; in the 'sustainable world' the main challenge is to deal with common problems with implications for the redefining of the value of clean fuels and processes as well as substantial reconstruction of the energy industry. 10 figs.
Griffiths, Danielle; Mullock, Alex
The market for cosmetic surgery tourism is growing with an increase in people travelling abroad for cosmetic surgery. While the reasons for seeking cosmetic surgery abroad may vary the most common reason is financial, but does cheaper surgery abroad carry greater risks? We explore the risks of poorly regulated cosmetic surgery to society generally before discussing how harm might be magnified in the context of cosmetic tourism, where the demand for cheaper surgery drives the market and makes surgery accessible for increasing numbers of people. This contributes to the normalisation of surgical enhancement, creating unhealthy cultural pressure to undergo invasive and risky procedures in the name of beauty. In addressing the harms of poorly regulated surgery, a number of organisations purport to provide a register of safe and ethical plastic surgeons, yet this arguably achieves little and in the absence of improved regulation the risks are likely to grow as the global market expands to meet demand. While the evidence suggests that global regulation is needed, the paper concludes that since a global regulatory response is unlikely, more robust domestic regulation may be the best approach. While domestic regulation may increase the drive towards foreign providers it may also have a symbolic effect which will reduce this drive by making people more aware of the dangers of surgery, both to society and individual physical wellbeing.
Sutton, M.A.; Howard, C.M. [NERC Centre for Ecology and Hydrology, Edinburgh (United Kingdom); Bleeker, A. [Energy research Centre of the Netherlands, Petten (Netherlands); Datta, A. [United Nations Environment Programme, Nairobi (Kenya)
Among the many environment and development challenges facing humanity, it is fair to say that nutrients do not currently feature so regularly in the newspapers, radio and television. The media tends to prefer easy single issues which affect our daily lives in a clear-cut way. The role of carbon in climate change is a good example. We all depend on climate. Burning fossil fuels makes more carbon dioxide, tending to change temperature and rainfall patterns, to which we can easily relate. The science is complex, but it is a simple message for the public to understand. It does not take long to think of several other easily grasped threats, like urban air pollution, poor drinking water, or even the occurrence of horsemeat in food chains. It is perhaps for these reasons that the role of nutrients in environmental change has received much less public attention. After all, nutrients - including nitrogen, phosphorus and many micronutrients - play multiple roles in our world; they affect many biogeochemical processes and they lead to a plethora of interacting threats. If we are not careful, we can quickly get buried in the complexity of the different ways in which our lives are affected by these elements. The outcome is that it can become hard to convey the science of global nutrient cycles in a way that the public can understand. These are points about which we have given substantial thought as we contributed to a recently launched report Our Nutrient World: The challenge to produce more food and energy with less pollution (Sutton et al., 2013). The report was commissioned by the United Nations Environment Programme (UNEP) and conducted by the Global Partnership on Nutrient Management in cooperation with the International Nitrogen Initiative. The commission was not to provide a full scientific assessment, but rather to develop a global overview of the challenges associated with nutrient management. Drawing on existing knowledge, the aim was to distill the nature of the
Val, Jonatan; Pino, Rosa; Navarro, Enrique; Chinarro, David
Global change, as a combination of climate change, human activities on watersheds and the river flow regulation, causes intense changes in hydrological cycles and, consequently, threatens the good ecological status of freshwater biological communities. This study addresses how and whether the combination of climatic drivers and local human impacts may alter the metabolism of freshwater communities. We identified a few factors modulating the natural water flow and quality in 25 point spread within the Ebro river Basin: waste water spills, industrial spills, reservoir discharges, water withdrawals, agricultural use, and the presence of riparian forests. We assessed their impacts on the freshwater metabolism as changes in the annual cycle of both gross primary production-GPP - and ecosystem respiration-ER -. For this purpose, daily data series were analyzed by continuous wavelet transformation, allowing for the assessment of the metabolic ecosystem Frequency Spectrum Patterns (FSPs). Changes in the behavior of ecosystem metabolism were strongly associated with local characteristics at each sampling point, however in 20 out of 25 studied points, changes in metabolic ecosystem FSP were related to climatic change events (the driest period of the last 140years). The changes in FSP indicate that severe impacts on how biological communities use carbon sources occur as a result of the human water management - too much focus on human needs - during intense climatic events. Results show that local factors, and specially the flow regulation, may modulate the impact of global change. As example those points exposed to a more intense anthropization showed a clear disruption - and even disappearance - of the annual FSP. This information may help managers to understand the action mechanisms of non-climatic factors at ecosystem level, leading to better management policies based on the promotion of ecosystem resilience. The method here presented may help on improving the calculation
E. Paul J. Gibbs, BVSc, PhD, FRCVS
Full Text Available ‘One World - One Health’ is an exciting movement to encourage wildlife, domestic animal and human health professionals to work collectively to address the world’s most challenging health concerns. It is broad in scope and truly multidisciplinary. This particular commentary on ‘One World - One Health’ is focused on ways in which individuals are forging closer collaboration and action to meet the global threat of emerging diseases caused by viruses, with particular attention being paid to those diseases that are zoonotic.
Crosby, C. J.; Nandigam, V.; Phan, M.; Youn, C.; Baru, C.; Arrowsmith, R.
OpenTopography (OT) is a geoinformatics-based data facility initiated in 2009 for democratizing access to high-resolution topographic data, derived products, and tools. Hosted at the San Diego Supercomputer Center (SDSC), OT utilizes cyberinfrastructure, including large-scale data management, high-performance computing, and service-oriented architectures to provide efficient Web based access to large, high-resolution topographic datasets. OT collocates data with processing tools to enable users to quickly access custom data and derived products for their application. OT's ongoing R&D efforts aim to solve emerging technical challenges associated with exponential growth in data, higher order data products, as well as user base. Optimization of data management strategies can be informed by a comprehensive set of OT user access metrics that allows us to better understand usage patterns with respect to the data. By analyzing the spatiotemporal access patterns within the datasets, we can map areas of the data archive that are highly active (hot) versus the ones that are rarely accessed (cold). This enables us to architect a tiered storage environment consisting of high performance disk storage (SSD) for the hot areas and less expensive slower disk for the cold ones, thereby optimizing price to performance. From a compute perspective, OT is looking at cloud based solutions such as the Microsoft Azure platform to handle sudden increases in load. An OT virtual machine image in Microsoft's VM Depot can be invoked and deployed quickly in response to increased system demand. OT has also integrated SDSC HPC systems like the Gordon supercomputer into our infrastructure tier to enable compute intensive workloads like parallel computation of hydrologic routing on high resolution topography. This capability also allows OT to scale to HPC resources during high loads to meet user demand and provide more efficient processing. With a growing user base and maturing scientific user
Lessin, Gennadi; Artioli, Yuri; Bruggeman, Jorn; Aldridge, John; Blackford, Jerry
Understanding the role of benthic systems in supporting, regulating and providing marine ecosystem services requires better understanding of their functioning and their response and resilience to stressors. Novel observational methods for the investigation of dynamics of benthic-pelagic coupling in shelf seas are being developed and new data is being collected. Therefore there is an increasing demand for robust representation of benthic processes in marine biogeochemical and ecosystem models, which would improve our understanding of whole systems and benthic-pelagic coupling, rather than act as mere closure terms for pelagic models. However, for several decades development of benthic models has lagged behind their pelagic counterparts. To address contemporary scientific, policy and societal challenges, the biogeochemical and ecological model ERSEM (European Regional Seas Ecosystem Model), including its benthic sub-model, was recently recoded in a scalable and modular format adopting the approach of FABM (Framework for Aquatic Biogeochemical Models). Within the Shelf Sea Biogeochemistry research programme, a series of additional processes have been included, such as a sedimentary carbonate system, a resuspendable fluff layer, and the simulation of advective sediments. It was shown that the inclusion of these processes changes the dynamics of benthic-pelagic fluxes as well as modifying the benthic food web. Comparison of model results with in-situ data demonstrated a general improvement of model performance and highlighted the importance of the benthic system in overall ecosystem dynamics. As an example, our simulations have shown that inclusion of a resuspendable fluff layer facilitates regeneration of inorganic nutrients in the water column due to degradation of resuspended organic material by pelagic bacteria. Moreover, the composition of fluff was found to be important for trophic interactions, and therefore indirectly affects benthic community composition. Where
I Nyoman Darma Putra
Full Text Available AbstractIn September and October 2013, only one week apart,Bali hosted two global events in the upper class markettourism resort Nusa Dua. The first event was the MissWorld beauty pageant, and the other one was the APECSummit. Thousands of journalists from all over the worldcovered these events. From a tourism marketing point ofview, these two prestigious events helped Bali boost itspopularity through global mass media. Historically, sincethe early phase of its development, Bali’s tourism industryhas received many benefits from global forces initiallychanneled out through the Dutch colonial power in the firstdecade of the twentieth century and later through nationaland multinational corporations. The recent enlisting byUNESCO of Bali’s cultural landscape as a world heritagesite (2012 provides yet another great example of how Balicontinues to receive global endorsement by world institutions as a unique tourism destination. This paper discusesopportunities and challenges caused by globalizationand localization phenomena in the management of Bali’stourism island destination. Bali’s experiences provide aninteresting example of how global and local stakeholdersdevelop the island tourism in a sustainable manner whileat the same time continuing to preserve its local arts andculture as one of its main attractions. While there aremany examples how both forces contribute to numerousopportunities toward the development of Bali’s tourism,it is also true to state that impacts of globalization causesvarious forms of distraction for the island’s ability to takefull control of its vast move of development.
Full Text Available To complement this Special Feature on global water governance, we focused on a generic challenge at the global level, namely, the degree to which water issues need to be dealt with in a centralized, concentrated, and hierarchical manner. We examined water ecosystem services and their impact on human well-being, the role of policies, indirect and direct drivers in influencing these services, and the administrative level(s at which the provision of services and potential trade-offs can be dealt with. We applied a politics of scale perspective to understand motivations for defining a problem at the global or local level and show that the multilevel approach to water governance is evolving and inevitable. We argue that a centralized overarching governance system for water is unlikely and possibly undesirable; however, there is a need for a high-level think tank and leadership to develop a cosmopolitan perspective to promote sustainable water development.
Lamichhane, Jay Ram; Aubertot, J-N; Begg, Graham;
of designing effective pest management strategies, which rely less heavily on the use of conventional pesticides, is another external challenge. Internal challenges include organizational aspects such as decreasing trend in budget allocated to IPM research, increasing scarcity of human expertise, lack...... networking experiences in Europe emphasizing how IPM research, implementation and adoption in Europe may benefit from a broader level networking....
Beek, K. J.; van Gils, H. A. M. J.
The public's increasing concern about environmental degradation is creating new demands for environmental monitoring and appropriate interventions to reduce or eliminate the sources and causes of environmental damage. We have two invaluable tools for addressing environmental problems: satellite remote sensing for collecting the essential data, and geographic information systems (GIS) for processing and evaluating these data and modelling the effects of various environmental management options. As educators, we have a special challenge to train the scientists who will be responsible for carrying out this work. An interdisciplinary approach is required to understand the multiple causes and effects of environmental problems, and special skills are needed to convey this information to the government agencies and individuals who can implement corrective measures. We have been quite successful at ITC in integrating remote sensing and GIS for environmental monitoring within our research and education programmes. Our present (and future) efforts are directed towards reinforcing the interdisciplinary approach considered essential in environmental management.
Christ, Tanya; Wang, X. Christine
This study explored whether or not, and how, an on-site and research-teacher community of practice model for professional development addressed the challenges to classroom practices in a Head Start program. Data sources included interviews with teachers, videos of planning and teaching sessions, and the researchers' fieldwork log and…
Ra, Sungsup; Chin, Brian; Lim, Cher Ping
Information and Communication Technology (ICT) offers opportunities for governments to address key education challenges of quality, equity, and efficiency. While governments and educational institutions in developed countries may have taken up these opportunities, many developing countries in Asia and the Pacific region have often missed them out.…
Shell's relationship with Norway goes back a long way and is very important to our future as well, as is evident from this presentation, which describes some of the pressures on a global energy business like Shell. It also deals with the fundamental importance of technology in the way we respond to those pressures. The power of innovation, and of partnerships, in keeping us at the front of the wave and, using our experiences, it is described how we at Shell deal with these issues. It also gives some examples of the benefits that have come out of our partnerships here in Norway, and the challenges and opportunities confronting those partnerships in the future.
discusses the health effects later in life of under-nutrition in the womb. The dynamics between food, health, population size and economy was the subject of Larsen, who showed how — over prehistoric and historic times — diets have changed, and also that the proportions of energy-rich and more nutritious......The present volume is based on presentations at a symposium at the Royal Danish Academy of Sciences and Letters in September 2014 with the title Food, Population and Health – global Patterns and Challenges. Food has played a fundamental role in the history of all societies over the World....... Availability and abundance of food has been crucial for the health and subsequently for the wealth of societies. In the first section Bothmer points out that agriculture began about 10 000 BP and that the first domesticated crops were grasses that subsequently underwent migration and adaptations and finally...
Percent of Labor Hours Spent on Scrap, Rework , and Repair for the F-35 Joint Strike Fighter 20 Figure 8: Average Number of F-35 Joint Strike Fighter...engine failure, and a higher than expected amount of test point growth largely to address software rework , over the past year, delayed key test...percent growth in mission system software test points for the year— largely to address software rework that might be needed—officials from the
Döll, Petra; Douville, Hervé; Güntner, Andreas; Müller Schmied, Hannes; Wada, Yoshihide
Quantification of spatially and temporally resolved water flows and water storage variations for all land areas of the globe is required to assess water resources, water scarcity and flood hazards, and to understand the Earth system. This quantification is done with the help of global hydrological models (GHMs). What are the challenges and prospects in the development and application of GHMs? Seven important challenges are presented. (1) Data scarcity makes quantification of human water use difficult even though significant progress has been achieved in the last decade. (2) Uncertainty of meteorological input data strongly affects model outputs. (3) The reaction of vegetation to changing climate and CO2 concentrations is uncertain and not taken into account in most GHMs that serve to estimate climate change impacts. (4) Reasons for discrepant responses of GHMs to changing climate have yet to be identified. (5) More accurate estimates of monthly time series of water availability and use are needed to provide good indicators of water scarcity. (6) Integration of gradient-based groundwater modelling into GHMs is necessary for a better simulation of groundwater-surface water interactions and capillary rise. (7) Detection and attribution of human interference with freshwater systems by using GHMs are constrained by data of insufficient quality but also GHM uncertainty itself. Regarding prospects for progress, we propose to decrease the uncertainty of GHM output by making better use of in situ and remotely sensed observations of output variables such as river discharge or total water storage variations by multi-criteria validation, calibration or data assimilation. Finally, we present an initiative that works towards the vision of hyperresolution global hydrological modelling where GHM outputs would be provided at a 1-km resolution with reasonable accuracy.
Doll, Petra; Douville, Herve; Guntner, Andreas; Schmied, Hannes Muller; Wada, Yoshihide
Quantification of spatially and temporally resolved water flows and water storage variations for all land areas of the globe is required to assess water resources, water scarcity and flood hazards, and to understand the Earth system. This quantification is done with the help of global hydrological models (GHMs). What are the challenges and prospects in the development and application of GHMs? Seven important challenges are presented. (1) Data scarcity makes quantification of human water use difficult even though significant progress has been achieved in the last decade. (2) Uncertainty of meteorological input data strongly affects model outputs. (3) The reaction of vegetation to changing climate and CO2 concentrations is uncertain and not taken into account in most GHMs that serve to estimate climate change impacts. (4) Reasons for discrepant responses of GHMs to changing climate have yet to be identified. (5) More accurate estimates of monthly time series of water availability and use are needed to provide good indicators of water scarcity. (6) Integration of gradient-based groundwater modelling into GHMs is necessary for a better simulation of groundwater-surface water interactions and capillary rise. (7) Detection and attribution of human interference with freshwater systems by using GHMs are constrained by data of insufficient quality but also GHM uncertainty itself. Regarding prospects for progress, we propose to decrease the uncertainty of GHM output by making better use of in situ and remotely sensed observations of output variables such as river discharge or total water storage variations by multi-criteria validation, calibration or data assimilation. Finally, we present an initiative that works towards the vision of hyper resolution global hydrological modelling where GHM outputs would be provided at a 1-km resolution with reasonable accuracy.
Full Text Available This paper tries to explore the different ways in which online learning platforms can be used to address learning challenges for students at the University of Mauritius. The main challenges identified were in the form of large number of students in class, the lecturer being unable to give individual attention to each student and the inability to cover all material in the given time frame. Themain problems encountered by students were in the form of inability to ask questions due to the large class size, lack of interaction with the lecturer and in some cases the lack of supplementary material. Findings indicate that online learning platforms can indeed be used to address learning challenges so that the online learning platforms supplement and complement traditional face-to-face lectures.
Patwardhan, Kishor; Gehlot, Sangeeta; Singh, Girish; Rathore, H C S
In the present day scenario, Ayurveda is globally being perceived in several contradictory ways. Poor quality of Ayurveda graduates produced as a result of poorly structured and poorly regulated education system is at least one of the important factors responsible for this scenario. The present study was carried out to evaluate the 'Global challenges of graduate level Ayurvedic education' and is based on the responses of Ayurvedic students and Ayurvedic teachers from various educational institutions of India to a methodically validated questionnaire. As the study indicates, the poor standard of Ayurvedic education in India is definitely a cause of concern. The curriculum of Bachelor of Ayurvedic Medicine and Surgery (BAMS) course of studies is required to be reviewed and restructured. The syllabi are required to be updated with certain relevant topics like laws governing the intellectual property rights, basic procedures of standardization of medicinal products, fundamental methods of evaluating the toxicity of the medicinal products, essentials of healthcare management and the basics of cultivation and marketing of medicinal plants. Furthermore, the study suggests that the Ayurvedic academicians are required to be trained in standard methods of research and documentation skills, and the educational institutions are required to be encouraged to contribute their share in building up the evidence base for Ayurveda in the form of quality education and research.
The aim of this review is to provide a global perspective of Home Enteral Tube Feeding (HETF) and to outline some of the challenges of home enteral nutrition (HEN) provisions. It is well established that the number of patients on HETF is on the increase worldwide due to advances in technology, development of percutaneous endoscopic gastrostomy techniques, and the shift in care provisions from acute to community settings. While the significance of home enteral nutrition in meeting the nutritional requirements of patients with poor swallowing reflexes and those with poor nutritional status is not in doubt, differences exist in terms of funding, standards, management approaches and the level of infrastructural development across the world. Strategies for alleviating some of the challenges militating against the effective delivery of HETF including the development of national and international standards, guidelines and policies for HETF, increased awareness and funding by government at all levels were discussed. Others, including development of HEN services, which should create the enabling environment for multidisciplinary team work, clinical audit and research, recruitment and retention of specialist staff, and improvement in patient outcomes have been outlined. However, more research is required to fully establish the cost effectiveness of the HEN service especially in developing countries and to compare the organization of HEN service between developing and developed countries.
Full Text Available The aim of this review is to provide a global perspective of Home Enteral Tube Feeding (HETF and to outline some of the challenges of home enteral nutrition (HEN provisions. It is well established that the number of patients on HETF is on the increase worldwide due to advances in technology, development of percutaneous endoscopic gastrostomy techniques, and the shift in care provisions from acute to community settings. While the significance of home enteral nutrition in meeting the nutritional requirements of patients with poor swallowing reflexes and those with poor nutritional status is not in doubt, differences exist in terms of funding, standards, management approaches and the level of infrastructural development across the world. Strategies for alleviating some of the challenges militating against the effective delivery of HETF including the development of national and international standards, guidelines and policies for HETF, increased awareness and funding by government at all levels were discussed. Others, including development of HEN services, which should create the enabling environment for multidisciplinary team work, clinical audit and research, recruitment and retention of specialist staff, and improvement in patient outcomes have been outlined. However, more research is required to fully establish the cost effectiveness of the HEN service especially in developing countries and to compare the organization of HEN service between developing and developed countries.
Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; 4 Blyth, Eleanor; de Roo, Ad; Doell. Petra; Ek, Mike; Famiglietti, James; Gochis, David; van de Giesen, Nick; Houser, Paul; Jaffe, Peter R.; Kollet, Stefan; Lehner, Bernhard; Lettenmaier, Dennis P.; Peters-Lidard, Christa; Sivpalan, Murugesu; Sheffield, Justin; Wade, Andrew; Whitehead, Paul
Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (approx.10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 10(exp 9) unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a grand challenge to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.
Hyder, Adnan A; Allen, Katharine A; Di Pietro, Gayle; Adriazola, Claudia A; Sobel, Rochelle; Larson, Kelly; Peden, Margie
Yearly, more than 1.2 million people are killed by road traffic injuries (RTIs) around the globe, and another 20 to 50 million are injured. The global burden of RTIs is predicted to rise. We explored the need for concerted action for global road safety and propose characteristics of an effective response to the gap in addressing RTIs. We propose that a successful response includes domains such as strong political will, capacity building, use of evidence-based interventions, rigorous evaluation, increased global funding, multisectoral action, and sustainability. We also present a case study of the global Road Safety in 10 Countries project, which is a new, 5-year, multipartner initiative to address the burden of RTIs in 10 low- and middle-income countries.
Mohammad Reza Mollahoseini Ardakani
Full Text Available In today's globally networked environment, enterprises need collaborating using Information Technology (IT and other tools to succeed in this dynamic and heterogeneous business environment. The Global Village Services Reference Model (GVSRM is a model based on SOSA (Service Oriented Strategies and Architectures ontology for global village services realization. In this model, three architectural abstraction layers have been considered for global village: ‘infrastructure for global village services’, ‘global village services provisioning’, and ‘using global village services’. Despite of relative completeness of this model, one of its obvious shortcomings is lack of attention to the crucial issue of interoperability in the global village. Based on this model, the grid of global village is comprised of VHGs (Virtual Holding Governance. The VHG is a temporary, scalable, dynamic cluster/association comprising of existing or newly service provider organizations which its aim is satisfying the requirements of global village actors through electronic processes. In this paper, we will propose a federated approach for interoperability among the VHGs of the global village and then improve the GVSRM by adding the corresponding interoperability components to it.
Hilpert, Simon; Günther, Stephan; Kaldemeyer, Cord
The process of modelling energy systems is accompanied by challenges inherently connected with mathematical modelling. However, due to modern realities in the 21st century, existing challenges are gaining in magnitude and are supplemented with new ones. Modellers are confronted with a rising...... complexity of energy systems and high uncertainties on different levels. In addition, interdisciplinary modelling is necessary for getting insight in mechanisms of an integrated world. At the same time models need to meet scientific standards as public acceptance becomes increasingly important....... In this intricate environment model application as well as result communication and interpretation is also getting more difficult. In this paper we present the open energy modelling framework (oemof) as a novel approach for energy system modelling and derive its contribution to existing challenges. Therefore, based...
This article addresses wife abuse in undocumented Mexican immigrant couples and suggests an ecosystems treatment approach that takes into consideration the structural forces of oppression and discrimination on abusive behaviors in the home and combines individual, family and community level interventions to help immigrant men stop the abuse.…
Mil, van H.G.J.; Foegeding, E.A.; Windhab, E.J.; Perrot, N.; Linden, van der E.
The quality and amount of the world food supply is crucial to the well-being of every human on the planet in the basic sense that we need food to live. It also has a profound impact on world economy, international trade, and global political stability. The choice of land used for agriculture, and th
... foreign oil, to create jobs, and to help U.S. industry compete successfully in global markets for clean... strategy. The American Recovery and Reinvestment Act of 2009 (``Recovery Act'') took large, initial steps..., comprehensive strategy in partnership with the states that will further President Obama's comprehensive...
Cohen, Asi; Bont, LJ; Engelhard, Dan; Moore, Edward; Fernandez, David; Kreisberg-Greenblatt, Racheli; Oved, Kfir; Eden, Eran; Hays, John P.
The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagno
Wilson, Amy T.; Winiarczyk, Rowena E.
Deaf people, members of a complex global language minority, have been excluded from positions of power in the field of humanitarian aid and development assistance, as well as from playing a significant role in the conduct of research that affects their lives. Deaf people rarely lead or participate as researchers in studies about their own…
Full Text Available Strengthening the external action of the Union has emerged as a powerful expectation shared both by a large majority of members of the Convention on the future of Europe, and more significantly by public opinion when it has been consulted on this issue. Although there is a consensual desire for Europe to speak with a stronger voice in global affairs, the ways and means to achieve this objective still divide those called to clarify the path to be followed. The European Union is already a significant presence in world politics by its considerable share in the international trade, or its dominant contribution to development aid. Many criticise on the other hand the lack of consistency in the more classical dimensions of foreign policy, or the lack of credibility in the capacity to act attributed to the absence of defence capabilities. Such concerns are currently addressed in the larger debate on the future of Europe, either within the dedicated framework, the European Convention convened to design the future of the EU, or outside the Convention, both among politicians and academics. It is generally considered and accepted that Europe will gain in political influence once the unification of the continent is completed, i.e. the current enlargement objectives are achieved. It goes without saying that devising and making operational appropriate instruments and capacities to act coherently outside its borders are a necessity as well. Institutional guarantees that Europe could in the future continue to influence the course of events in world affairs are becoming imperative. This article will explore some of the proposals in that sense. It will also address the place for Romania as a future EU member state in the new architecture of Europe and its possible contribution to the Common Foreign and Security Policy.
Guercio, Angela; Stirbens, Kathleen A.; Williams, Joseph; Haiber, Charles
Searching for relevant information on the web is an important aspect of distance learning. This activity is a challenge for visually impaired distance learners. While sighted people have the ability to filter information in a fast and non sequential way, blind persons rely on tools that process the information in a sequential way. Learning is…
The purpose of this article is to highlight the challenges that accomplished young athletes face as they aspire to become professional athletes. The data used in this study was derived from selected lived and told sport experiences of undergraduate and graduate kinesiology majors who were former competitive athletes. Additional data was derived…
Khaddage, Ferial; Christensen, Rhonda; Lai, Wing; Knezek, Gerald; Norris, Cathie; Soloway, Elliot
In this paper a review of the pedagogical, technological, policy and research challenges and concepts underlying mobile learning is presented, followed by a brief description of categories of implementations. A model Mobile learning framework and dynamic criteria for mobile learning implementations are proposed, along with a case study of one site…
Heppner, P. Paul
The central thesis of this article is that focusing on cross-cultural competence will enhance both the science and the practice of counseling psychology. Developing cross-cultural competence is a lifelong journey, replete with many joys and challenges, that will (a) increase the sophistication of our research, (b) expand the utility and…
Aptima, Inc. Technical Review by William Bickley, U.S. Army Research Institute Heather Priest-Walker, U.S. Army Research Institute...training challenges at home station and at Aviation Training Exercises. This report benefitted from the thoughtful comments of Drs. William Bickley and...environment, cockpit instrumentation, communications, weapons systems, gunnery environment, AH64 TADS , NVG (Night Vision Goggles) Simulation, EDMs
Peterman, Carla Joy
Paper 1, Local Solutions to Global Problems: Climate Change Policies and Regulatory Jurisdiction, considers the efficacy of various types of environmental regulations when they are applied locally to pollutants whose damages extend beyond the jurisdiction of the local regulators. Local regulations of a global pollutant may be ineffective if producers and consumers can avoid them by transacting outside the reach of the local regulator. In many cases, this may involve the physical relocation of the economic activity, a problem often referred to as "leakage." This paper highlights another way in which local policies can be circumvented: through the shuffling of who buys from whom. The paper maintains that the problems of reshuffling are exacerbated when the options for compliance with the regulations are more flexible. Numerical analyses is presented demonstrating that several proposed policies to limit greenhouse gas emissions from the California electricity sector may have very little effect on carbon emissions if they are applied only within that state. Paper 1 concludes that although local subsidies for energy efficiency, renewable electricity, and transportation biofuels constitute attempts to pick technology winners, they may be the only mechanisms that local jurisdictions, acting alone, have at their disposal to address climate change. Paper 2, Pass-Through of Solar PV Incentives to Consumers: The Early Years of California's Solar PV Incentives, examines the pass through of incentives to California solar PV system owners. The full post-subsidy price consumers pay for solar power is a key metric of the success of solar PV incentive programs and of overall PV market performance. This study examines the early years of California's most recent wave of distributed solar PV incentives (2000-2008) to determine the pass-through of incentives. Examination of this period is both intellectually and pragmatically important due to the high level of incentives provided and
Tromp, J.; Bozdag, E.; Krischer, L.; Lefebvre, M.; Lei, W.; Smith, J.
The challenge of imaging Earth's interior on a global scale is closely linked to the challenge of handling large data sets. The related iterative workflow involves five distinct phases, namely, 1) data gathering and culling, 2) synthetic seismogram calculations, 3) pre-processing (time-series analysis and time-window selection), 4) data assimilation and adjoint calculations, 5) post-processing (pre-conditioning, regularization, model update). In order to implement this workflow on modern high-performance computing systems, a new seismic data format is being developed. The Adaptable Seismic Data Format (ASDF) is designed to replace currently used data formats with a more flexible format that allows for fast parallel I/O. The metadata is divided into abstract categories, such as "source" and "receiver", along with provenance information for complete reproducibility. The structure of ASDF is designed keeping in mind three distinct applications: earthquake seismology, seismic interferometry, and exploration seismology. Existing time-series analysis tool kits, such as SAC and ObsPy, can be easily interfaced with ASDF so that seismologists can use robust, previously developed software packages. ASDF accommodates an automated, efficient workflow for global adjoint tomography. Manually managing the large number of simulations associated with the workflow can rapidly become a burden, especially with increasing numbers of earthquakes and stations. Therefore, it is of importance to investigate the possibility of automating the entire workflow. Scientific Workflow Management Software (SWfMS) allows users to execute workflows almost routinely. SWfMS provides additional advantages. In particular, it is possible to group independent simulations in a single job to fit the available computational resources. They also give a basic level of fault resilience as the workflow can be resumed at the correct state preceding a failure. Some of the best candidates for our particular workflow
Director, Office of Acquisition Resources and Analysis ( ARA ) Deputy Assistant Secretary of the Navy, Acquisition & Procurement Director of Open...Asuncion, 2010; Scacchi & Alspaugh, 2008) may therefore be extendable to also address OA systems with heterogeneous software security license rights and... heterogeneously licensed systems. In Proceedings of the 17th IEEE International Requirements Engineering Conference (pp. 24–33). Alspaugh, T. A., Asuncion, H
van Mil, H G J; Windhab, E J; Perrot, N; van der Linden, E
World food supply is crucial to the well-being of every human on the planet in the basic sense that we need food to live. It also has a profound impact on the world economy, international trade and global political stability. Furthermore, consumption of certain types and amounts foods can affect health, and the choice of livestock and plants for food production can impact sustainable use of global resources. There are communities where insufficient food causes nutritional deficiencies, and at the same time other communities eating too much food leading to obesity and accompanying diseases. These aspects reflect the utmost importance of agricultural production and conversion of commodities to food products. Moreover, all factors contributing to the food supply are interdependent, and they are an integrative part of the continuously changing, adaptive and interdependent systems in the world around us. The properties of such interdependent systems usually cannot be inferred from the properties of its parts. In a...
Many countries are at a crossroads in terms of maintaining their energy supply. The existing resources of fossil fuels are dwindling, and global warming makes their use increasingly problematic. Nuclear power is now often regarded inevitable for future sustainability, energy security, and economic prosperity. There are, however, still unsolved problems regarding nuclear power. The fact that no country has established a final waste repository for spent nuclear fuel throws fundamental doubt on nuclear energy expansion. Also, the processes of globalization have transformed the nuclear industry towards increased privatization, concentration, and internationalization. This leads to uncertainties regarding the responsibility for nuclear waste management. In these circumstances is it of greatest importance that scholars from different disciplines, as well as policy makers and practitioners within the field, meet to share experiences. This conference had the general objective of producing knowledge about the challenges caused by global developmental trends, and what the management of nuclear waste implies for contemporary and future social development. Over 100 persons attended the conferences. Papers available at the conference site have been separately indexed. Several contributions were also made as PP-presentation, which are available at the site, among others the Keynote Speeches: Waiting for the Nuclear Renaissance: Exploring the Nexus of Expansion and Disposal in Europe (Jane Dawson); Applying the Risk Governance Framework: Institutional Requirements for Dealing with Nuclear Waste (Ortwin Renn); Learning to Listen: The Long Road to Legitimating Radioactive Waste Management Policies (Frans Berkhout); The Nuclear Waste Debate is Irrational but We Need Not Panic (Frank von Hippel). The conference was divided into the following sessions: Session A: Political characteristics matters; Session B: Radioactivity, geology, society. On a problem definition of HLW
Full Text Available The purpose of the Social Plan Guidelines is to manage large-scale retrenchments and ameliorate their effects on employees. In this study a comprehensive literature review and two case studies were conducted to review the theoretical and practical application of the Social Plan. The research findings identified various challenges that inhibit the effective management of retrenchments. These challenges were analysed and interpreted and a new model to effectively manage retrenchments was developed. The new model is centred on a company’s business plan; the concept is a participative performance-driven governance approach between management and employees focusing on business results. The new model suggests that the employment relations management and corporate social investment of an organisation be utilised as vehicles to manage retrenchments effectively.
Brennan, Frank R; Baumann, Andreas; Blaich, Guenter; de Haan, Lolke; Fagg, Rajni; Kiessling, Andrea; Kronenberg, Sven; Locher, Mathias; Milton, Mark; Tibbitts, Jay; Ulrich, Peter; Weir, Lucinda
Non-clinical safety testing of biopharmaceuticals can present significant challenges to human risk assessment with these often innovative and complex drugs. Hot Topics in this field were discussed recently at the 4th Annual European Biosafe General Membership meeting. In this feature article, the presentations and subsequent discussions from the main sessions are summarized. The topics covered include: (i) wanted versus unwanted immune activation, (ii) bi-specific protein scaffolds, (iii) use of Pharmacokinetic (PK)/Pharmacodynamic (PD) data to impact/optimize toxicology study design, (iv) cytokine release and challenges to human translation (v) safety testing of cell and gene therapies including chimeric antigen receptor T (CAR-T) cells and retroviral vectors and (vi) biopharmaceutical development strategies encompassing a range of diverse topics including optimizing entry of monoclonal antibodies (mAbs) into the brain, safety testing of therapeutic vaccines, non-clinical testing of biosimilars, infection in toxicology studies with immunomodulators and challenges to human risk assessment, maternal and infant anti-drug antibody (ADA) development and impact in non-human primate (NHP) developmental toxicity studies, and a summary of an NC3Rs workshop on the future vision for non-clinical safety assessment of biopharmaceuticals.
Ban, Yifang; Gong, Peng; Giri, Chandra
Land cover is an important variable for many studies involving the Earth surface, such as climate, food security, hydrology, soil erosion, atmospheric quality, conservation biology, and plant functioning. Land cover not only changes with human caused land use changes, but also changes with nature. Therefore, the state of land cover is highly dynamic. In winter snow shields underneath various other land cover types in higher latitudes. Floods may persist for a long period in a year over low land areas in the tropical and subtropical regions. Forest maybe burnt or clear cut in a few days and changes to bare land. Within several months, the coverage of crops may vary from bare land to nearly 100% crops and then back to bare land following harvest. The highly dynamic nature of land cover creates a challenge in mapping and monitoring which remains to be adequately addressed. As economic globalization continues to intensify, there is an increasing trend of land cover/land use change, environmental pollution, land degradation, biodiversity loss at the global scale, timely and reliable information on global land cover and its changes is urgently needed to mitigate the negative impact of global environment change.
Universal health access will not be achieved unless women are cared for in their own communities and are empowered to take decisions about their own health in a supportive environment. This will only be achieved by community-based demand side interventions for maternal health access. In this review article, we highlight three common strategies to increase demand-side barriers to maternal healthcare access and identify the main challenges that still need to be addressed for these strategies to be effective.
Giles-Corti, Billie; Vernez-Moudon, Anne; Reis, Rodrigo; Turrell, Gavin; Dannenberg, Andrew L; Badland, Hannah; Foster, Sarah; Lowe, Melanie; Sallis, James F; Stevenson, Mark; Owen, Neville
Significant global health challenges are being confronted in the 21st century, prompting calls to rethink approaches to disease prevention. A key part of the solution is city planning that reduces non-communicable diseases and road trauma while also managing rapid urbanisation. This Series of papers considers the health impacts of city planning through transport mode choices. In this, the first paper, we identify eight integrated regional and local interventions that, when combined, encourage walking, cycling, and public transport use, while reducing private motor vehicle use. These interventions are destination accessibility, equitable distribution of employment across cities, managing demand by reducing the availability and increasing the cost of parking, designing pedestrian-friendly and cycling-friendly movement networks, achieving optimum levels of residential density, reducing distance to public transport, and enhancing the desirability of active travel modes (eg, creating safe attractive neighbourhoods and safe, affordable, and convenient public transport). Together, these interventions will create healthier and more sustainable compact cities that reduce the environmental, social, and behavioural risk factors that affect lifestyle choices, levels of traffic, environmental pollution, noise, and crime. The health sector, including health ministers, must lead in advocating for integrated multisector city planning that prioritises health, sustainability, and liveability outcomes, particularly in rapidly changing low-income and middle-income countries. We recommend establishing a set of indicators to benchmark and monitor progress towards achievement of more compact cities that promote health and reduce health inequities.
The global meat industry has seen significant changes in the methods used to harvest and process fresh meat over the past century. Increased use of automation has led to significant increases in line speed for beef, pork, sheep, poultry and fish operations. For example, currently the fastest line observed has been broilers at 13,500/h. Such developments have required in-depth understanding of the pre and post rigor processes to prevent defects. Procedures such as maturation chilling and electrical stimulation are now common in red meat and poultry processing; allowing shorter time to deboning, while harvesting high quality meat. Robots designed to cut meat are also appearing on the market, and replacing traditional manual operations. This is a challenge, because high speed equipment is not necessarily sensitive to variations in size/quality issues, and requires development of unique sensors and control systems. Also, progress in breeding and genetics is contributing to greater product uniformity and quality; helping in operating automated equipment.
Hamlet, A. F.; Bolster, D.; Tank, J. L.; Hellmann, J.; Christopher, S. F.; Sharma, A.; Chiu, C. M.
The Midwest and Great Lakes region face a number of "Grand Challenges" associated with climate, land use, agriculture, and water resources infrastructure. These include sustainability of agricultural systems and related impacts to food security and the regional economy; sustainability of Great Lakes water levels; changing storm statistics and impacts to stormwater management and flooding; water quality in rivers and downstream receiving water bodies related to non-point source pollution on agricultural lands and combined sewer overflows in urban areas; urban impacts related to aging infrastructure and climate change, and ecosystem management and restoration. In the context of water management, groundwater resources are poorly understood in comparison with surface water resources, and regional-scale simulation models are needed to address questions of sustainability both in terms of supply and water quality. Interdisciplinary research at the University of Notre Dame is attempting to address these research challenges via 1) integrated macro-scale groundwater and surface water modeling to address issues related to sustainable water supply, ecosystem restoration, and agricultural impacts; 2) development of high-resolution regional climate models dynamically coupled to the Great Lakes to address urban impacts, changing storm statistics and to quantify precipitation and evaporation over the Great Lakes; 3) and integrated macro-scale hydrology and water quality modeling to assess the large-scale performance of innovative land management BMPs on agricultural land (such as the two-stage ditch, cover crops, and dynamic drainage control) intended to improve water quality.
renewable energy be generated by sources placed into service in 1999 or later; and (3) the 2007 Defense Authorization Act directed that at least 25 percent of electricity consumed by DoD come from renewable sources in fiscal year 2025. GAO was asked to examine the following: (1) DoD’s progress toward these three key goals for consuming renewable energy in fiscal years 2007 and 2008, (2) challenges to DoD meeting those goals, and (3) DoD’s plans to meet the goals. GAO reviewed relevant laws and DoD and Department of Energy (DOE) policy,
Janjic, Zavisa; Djurdjevic, Vladimir; Vasic, Ratko
are comparable to the scales of the dominant Rossby waves, such fictitious solutions are hard to identify and remove. Another new challenge on the global scale is that the limit of validity of the hydrostatic approximation is rapidly being approached. Relaxing the hydrostatic approximation requieres careful reformulation of the model dynamics and more computations and communications. The unified Non-hydrostatic Multi-scale Model (NMMB) will be briefly discussed as an example. The non-hydrostatic dynamics were designed in such a way as to avoid over-specification. The global version is run on the latitude-longitude grid, and the polar filter selectively slows down the waves that would otherwise be unstable without modifying their amplitudes. The model has been successfully tested on various scales. The skill of the medium range forecasts produced by the NMMB is comparable to that of other major medium range models, and its computational efficiency on parallel computers is good.
Drehobl, Patricia; Stover, Beth H; Koo, Denise
The public health workforce is vital to protecting the health and safety of the public, yet for years, state and local governmental public health agencies have reported substantial workforce losses and other challenges to the workforce that threaten the public's health. These challenges are complex, often involve multiple influencing or related causal factors, and demand comprehensive solutions. However, proposed solutions often focus on selected factors and might be fragmented rather than comprehensive. This paper describes approaches to characterizing the situation more comprehensively and includes two visual tools: (1) a fishbone, or Ishikawa, diagram that depicts multiple factors affecting the public health workforce; and (2) a roadmap that displays key elements-goals and strategies-to strengthen the public health workforce, thus moving from the problems depicted in the fishbone toward solutions. The visual tools aid thinking about ways to strengthen the public health workforce through collective solutions and to help leverage resources and build on each other's work. The strategic roadmap is intended to serve as a dynamic tool for partnership, prioritization, and gap assessment. These tools reflect and support CDC's commitment to working with partners on the highest priorities for strengthening the workforce to improve the public's health.
Peter USHER; Qian YE
Based on a historical review of the so-called Ozone crisis in the late 1970s and global climate changes since the 1980s, this paper examines the role of sciences and policies in the international community in dealing with the global environmental issues. Lessons show that a multi-discipline, multi-organizational and multi-national UN agency which remains relevant, assisting rather than guiding the process of climate negotiations is important.
Full Text Available Abstract In 2012, food insecurity is still a major global concern as 1 billion people are suffering from starvation, under-, and malnutrition, and the Food and Agriculture Organization of the United Nations (FAO has concluded that we are still far from reaching millennium development goal (MDG number 1: to halve extreme poverty and hunger by 2015. In sub-Saharan Africa, the number of people suffering from hunger is estimated at 239 million, and this figure could increase in the near future. There are many examples of food insecurity in sub-Saharan Africa, some of them having reached catastrophic dimensions, for example, in the Horn of Africa or southern Madagascar. Food insecurity is not just about insufficient food production, availability, and intake, it is also about the poor quality or nutritional value of the food. The detrimental situation of women and children is particularly serious, as well as the situation among female teenagers, who receive less food than their male counterparts in the same households. Soaring food prices and food riots are among the many symptoms of the prevailing food crisis and insecurity. Climate change and weather vagaries, present and forecast, are generally compounding food insecurity and drastically changing farming activities, as diagnosed by the Consultative Group on International Agricultural Research (CGIAR in June 2011. The key cause of food insecurity is inadequate food production. Since the global food crisis of 2007–2008, there has been an increasing awareness throughout the world that we must produce more and better food; and we should not be derailed from this goal, despite some relief brought by the good cereal harvests in 2011–2012. This is particularly true in sub-Saharan Africa, which needs and wants to make its own green revolution. The African challenge indeed is key to mitigating food insecurity in the world. Commitments were made by the heads of states and governments of the African Union
Reis, Stefan; Bekunda, Mateete; Howard, Clare M.; Karanja, Nancy; Winiwarter, Wilfried; Yan, Xiaoyuan; Bleeker, Albert; Sutton, Mark A.
One of the ‘grand challenges’ of this age is the anthropogenic impact exerted on the nitrogen cycle. Issues of concern range from an excess of fixed nitrogen resulting in environmental pressures for some regions, while for other regions insufficient fixed nitrogen affects food security and may lead to health risks. To address these issues, nitrogen needs to be managed in an integrated fashion, at a variety of scales (from global to local). Such management has to be based on a thorough understanding of the sources of reactive nitrogen released into the environment, its deposition and effects. This requires a comprehensive assessment of the key drivers of changes in the nitrogen cycle both spatially, at the field, regional and global scale and over time. In this focus issue, we address the challenges of managing reactive nitrogen in the context of food production and its impacts on human and ecosystem health. In addition, we discuss the scope for and design of management approaches in regions with too much and too little nitrogen. This focus issue includes several contributions from authors who participated at the N2013 conference in Kampala in November 2013, where delegates compiled and agreed upon the ‘Kampala Statement-for-Action on Reactive Nitrogen in Africa and Globally’. These contributions further underline scientifically the claims of the ‘Kampala Statement’, that simultaneously reducing pollution and increasing nitrogen available in the food system, by improved nitrogen management offers win-wins for environment, health and food security in both developing and developed economies. The specific messages conveyed in the Kampala Statement focus on improving nitrogen management (I), including the reduction of nitrogen losses from agriculture, industry, transport and energy sectors, as well as improving waste treatment and informing individuals and institutions (II). Highlighting the need for innovation and increased awareness among stakeholders (III
Aleksandra Anatol’evna Shabunova
Full Text Available The present-day world’s development is becoming more and more uneven and new global challenges are emerging. Russia should respond to them by enhancing its economic competitiveness, preserving and increasing its population and human potential, first of all, that of children and young people. The paper points out that for the Russian Federation with its vast territory and substantial reserves of natural resources the most important geopolitical challenges consist in the preservation and increase of population and human potential. The authors prove that the formation of the population of Russia is under double “pressure” of high mortality and low fertility; therefore, natural movement (decline is not completed by mechanical movement. In addition, the article determines that the share of young people in the total population is decreasing. For the first time in the history of Russia the share of children has become lower than the proportion of the elderly. In 2013 in 56 Russian regions, the proportion of children and adolescents accounted for less than 20% of the population (in the early 2000s, there were 41 such regions, and in 1990 – three. In addition to the reduction in the number of the population, child health potential is also deteriorating: about 35% of children in Russia are born ill or become ill in the near future (the figure is 30% in the Vologda Oblast. The number of adolescents aged 15–17 who are accounted for severe mental disorders is continuously increasing. The greatest socio-economic damage to the society comes from suicides that are widely spread among young people (the younger generation (persons up to 24 years old accounts for one third of all the potential years of life lost from suicides. At the same time, young people consider health more valuable than does the population as a whole (4.5 points vs 4.4 points on a five-point scale. But young people underestimate the importance of self-preservation behavior. World
Thingholm, Louise Bruun; Andersen, Lars; Makalic, Enes
The development and progression of cancer, a collection of diseases with complex genetic architectures, is facilitated by the interplay of multiple etiological factors. This complexity challenges the traditional single-platform study design and calls for an integrated approach to data analysis....... However, integration of heterogeneous measurements of biological variation is a non-trivial exercise due to the diversity of the human genome and the variety of output data formats and genome coverage obtained from the commonly used molecular platforms. This review article will provide an introduction...... to integration strategies used for analyzing genetic risk factors for cancer. We critically examine the ability of these strategies to handle the complexity of the human genome and also accommodate information about the biological and functional interactions between the elements that have been measured...
The paper is devoted to the analysis of the causes of decreasing Ukraine’s global competitiveness position, and the influence of the factors: “Higher education and training”, “Innovation”, “Institutions” on the global competitiveness of Ukrainian economy. The possibilities of increasing the global competitive position of Ukraine by intensification of innovative activity, development of the set of measures on strengthening the innovative components of global competitiveness have been examined....
Mercer, J. L.; Richter-Menge, J.; Weale, J. C.; Lever, J. H.; Knuth, M. A.; Shoop, S. A.; Haehnel, R.; Arcone, S. A.; Bjella, K.; Finnegan, D. C.; Courville, Z.; Tracy, B. T.
Logistics constraints and operational challenges in the austere environs of the polar regions present unique technological and engineering problems. Working closely with universities, government agencies and industry, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Lab (CRREL) routinely conducts scientific research and engineering in the Arctic, sub-Arctic and Antarctic covering a wide range of topics and applications. Current areas of focus include: improved mobility techniques for overland traverses; robotic vehicles for traversing, sampling and data collection; snow road and transportation characterization; integrated operational systems including airfield consolidation proof-of-concept studies; infrastructure technology such as firn air cooling, building design, snow foundations and sewage handling; remote/renewable autonomous power solutions for data collection; subsurface radar for crevasse detection and cryosphere characterization; ground-based lidar topographic scanning and near-real-time climate/environmental monitoring linked to AIS infrastructure. While these research and engineering efforts provide solutions and improved technology for specific problems, the impacts are many and wide-reaching and the results are often applicable to other challenging environments. Here, an overview of current research foci and projects is presented along with in-the-field applications, effects and future implications. The results and solutions of these efforts typically lead to technological improvements in operations and logistics which are cost-beneficial, thus freeing up funding dollars for fundamental scientific research. The links between basic research and applied solutions delivering far-reaching impacts (both large- and small-scale) on society, the environment, industry and scientific research are also demonstrated.
Antoniu Alexandru FLANDORFER
Full Text Available Along his history, Man has always been mesmerized by the ideal of creating an earthly paradise out of his habitat, so he implemented the vector of progress by means of the particular Myth that was inherent to each epoch. Man’s fascination with his exponential evolution in the world appeared with the industrial revolution that was gradually enhanced by the intrusion of politics. A mixture of political and socio-economic aspects was created with the sole purpose of consolidating such historical tendencies that led to the birth of the totalitarian regimes of the 20th c., taking the shapes of secular religions, (R. Aron, political / intra-mundane religions (E. Voegelin, religions of earthly redemption (E. Morin, ideologies of redemption (J. Freund. Nowadays, after the failure of politics, the semantic “pool” of collective imagination has received the addition of a new spasm of humankind that was generated by the following issues: the evolution of science up to a teleological praxis, the maximal efficiency of production leading to an inherent over-consumption, and, finally, the replacement of Christian morals by the ethical commandments of the society. Our research constitutes a phenomenological analysis of totalitarianism and the dystopian challenges of Globalization. We notice that both the Nazi or communist counter-utopias, and the present-day dystopia are the result of the secularization of religion; while the human being, stuck in a secular millenarianism, has sketched new coordinates in a godless environment. The solution to avoid humankind’s own moral suicide is to be found not in the social hypostases of individual, but in the return to mysticism. It is therefore necessary to return to the archetype rather than to a prototype that is permanently cloned in the process of uniformization of the society as a result of standardization and in the atomization of the individual through digital socialization.
Ryan, B. J.
Launched in 2005 by industrialized nations, the Group on Earth Observations (GEO) began building the Global Earth Observation System of Systems (GEOSS). Consisting of both a policy framework, and an information infrastructure, GEOSS, was intended to link and/or integrate the multitude of Earth observation systems, primarily operated by its Member Countries and Participating Organizations, so that users could more readily benefit from global information assets for a number of society's key environmental issues. It was recognized that having ready access to observations from multiple systems was a prerequisite for both environmental decision-making, as well as economic development. From the very start, it was also recognized that the shear complexity of the Earth's system cannot be captured by any single observation system, and that a federated, interoperable approach was necessary. While this international effort has met with much success, primarily in advancing broad, open data policies and practices, challenges remain. In 2014 (Geneva, Switzerland) and 2015 (Mexico City, Mexico), Ministers from GEO's Member Countries, including the European Commission, came together to assess progress made during the first decade (2005 to 2015), and approve implementation strategies and mechanisms for the second decade (2016 to 2025), respectively. The approved implementation strategies and mechanisms are intended to advance GEOSS development thereby facilitating the increased uptake of Earth observations for informed decision-making. Clearly there are interoperability challenges that are technological in nature, and several will be discussed in this presentation. There are, however, interoperability challenges that can be better characterized as economic, governmental and/or political in nature, and these will be discussed as well. With the emergence of the Sustainable Development Goals (SDGs), the World Conference on Disaster Risk Reduction (WCDRR), and the United Nations
Bousquet, J; Burney, P G; Zuberbier, T;
Allergic diseases represent a major health problem in Europe. They are increasing in prevalence, severity and costs. The Global Allergy and Asthma European Network (GA(2)LEN), a Sixth EU Framework Program for Research and Technological Development (FP6) Network of Excellence, was created in 2005...... as a vehicle to ensure excellence in research bringing together research and clinical institutions to combat fragmentation in the European research area and to tackle allergy in its globality. The Global Allergy and Asthma European Network has benefited greatly from the voluntary efforts of researchers who...... are strongly committed to this model of pan-European collaboration. The network was organized in order to increase networking for scientific projects in allergy and asthma around Europe and to make GA(2)LEN the world leader in the field. Besides these activities, research has also been carried out...
@@ Prof. Peter Gruss, president of the Max Planck Society (MPS) and a winner of China's National Award for International S&T Cooperation in 2007, has long been committed to promoting the scientific cooperation between China and Germany. As early as in the 1980s, he went to Shanghai to teach advanced experimental techniques at the Guest Laboratory cosponsored by CAS and MPS. Since 2002 when he assumed the office of MPS president,
Louise Bruun Thingholm
Full Text Available The development and progression of cancer, a collection of diseases with complex genetic architectures, is facilitated by the interplay of multiple etiological factors. This complexity challenges the traditional single-platform study design and calls for an integrated approach to data analysis. However, integration of heterogeneous measurements of biological variation is a non-trivial exercise due to the diversity of the human genome and the variety of output data formats and genome coverage obtained from the commonly used molecular platforms. This review article will provide an introduction to integration strategies used for analyzing genetic risk factors for cancer. We critically examine the ability of these strategies to handle the complexity of the human genome and also accommodate information about the biological and functional interactions between the elements that have been measured – making the assessment of disease risk against a composite genomic factor possible. The focus of this review is to provide an overview and introduction to the main strategies and to discuss where there is a need for further development.
Quinn, Heather M [Los Alamos National Laboratory; Dehon, Andre [U. PENN; Carter, Nicholas P [INTEL
We are rapidly approaching an inflection point where the conventional target of producing perfect, identical transistors that operate without upset can no longer be maintained while continuing to reduce the energy per operation. With power requirements already limiting chip performance, continuing to demand perfect, upset-free transistors would mean the end of scaling benefits. The big challenges in device variability and reliability are driven by uncommon tails in distributions, infrequent upsets, one-size-fits-all technology requirements, and a lack of information about the context of each operation. Solutions co-designed across traditional layer boundaries in our system stack can change the game, allowing architecture and software (a) to compensate for uncommon variation, environments, and events, (b) to pass down invariants and requirements for the computation, and (c) to monitor the health of collections of deVices. Cross-layer codesign provides a path to continue extracting benefits from further scaled technologies despite the fact that they may be less predictable and more variable. While some limited multi-layer mitigation strategies do exist, to move forward redefining traditional layer abstractions and developing a framework that facilitates cross-layer collaboration is necessary.
Research suggests that Alzheimer disease (AD) pathophysiology begins prior to the clinical expression of the disease and that biomarker measures may provide direct evidence of this process. As a result, it may be possible to uncouple the diagnosis of AD from the clinical expression of the disease. The shifting boundaries between normal brain aging and disease present 3 challenges: 1) establishing guidelines for researchers and clinicians to safely and effectively communicate the diagnosis of preclinical AD, 2) setting up a process that effectively translates this diagnosis into practice and policy, and 3) adapting laws, regulations, and professional practices to the diagnosis of preclinical AD. The field of genetic testing for AD suggests how to balance a patient's desire to know his or her risk of developing dementia with a clinician's desire to mitigate the potential harms of that information. The development of diagnostic and treatment guidelines for other diseases of aging, such as cardiovascular disease, suggests the need for a National Alzheimer's Education Program to develop policies and procedures to translate preclinical AD into both clinical practice and policy. Revisions are needed to laws, regulations, and professional practices governing driving, financial management and planning, and privacy and confidentiality.
Yager, Kevin; Albert, Thomas; Brower, Bernard V.; Pellechia, Matthew F.
The domain of Geospatial Intelligence Analysis is rapidly shifting toward a new paradigm of Activity Based Intelligence (ABI) and information-based Tipping and Cueing. General requirements for an advanced ABIAA system present significant challenges in architectural design, computing resources, data volumes, workflow efficiency, data mining and analysis algorithms, and database structures. These sophisticated ABI software systems must include advanced algorithms that automatically flag activities of interest in less time and within larger data volumes than can be processed by human analysts. In doing this, they must also maintain the geospatial accuracy necessary for cross-correlation of multi-intelligence data sources. Historically, serial architectural workflows have been employed in ABIAA system design for tasking, collection, processing, exploitation, and dissemination. These simpler architectures may produce implementations that solve short term requirements; however, they have serious limitations that preclude them from being used effectively in an automated ABIAA system with multiple data sources. This paper discusses modern ABIAA architectural considerations providing an overview of an advanced ABIAA system and comparisons to legacy systems. It concludes with a recommended strategy and incremental approach to the research, development, and construction of a fully automated ABIAA system.
Fitz, Rhonda; Whitman, Gerek
Research into complexities of software systems Fault Management (FM) and how architectural design decisions affect safety, preservation of assets, and maintenance of desired system functionality has coalesced into a technical reference (TR) suite that advances the provision of safety and mission assurance. The NASA Independent Verification and Validation (IV&V) Program, with Software Assurance Research Program support, extracted FM architectures across the IV&V portfolio to evaluate robustness, assess visibility for validation and test, and define software assurance methods applied to the architectures and designs. This investigation spanned IV&V projects with seven different primary developers, a wide range of sizes and complexities, and encompassed Deep Space Robotic, Human Spaceflight, and Earth Orbiter mission FM architectures. The initiative continues with an expansion of the TR suite to include Launch Vehicles, adding the benefit of investigating differences intrinsic to model-based FM architectures and insight into complexities of FM within an Agile software development environment, in order to improve awareness of how nontraditional processes affect FM architectural design and system health management. The identification of particular FM architectures, visibility, and associated IV&V techniques provides a TR suite that enables greater assurance that critical software systems will adequately protect against faults and respond to adverse conditions. Additionally, the role FM has with regard to strengthened security requirements, with potential to advance overall asset protection of flight software systems, is being addressed with the development of an adverse conditions database encompassing flight software vulnerabilities. Capitalizing on the established framework, this TR suite provides assurance capability for a variety of FM architectures and varied development approaches. Research results are being disseminated across NASA, other agencies, and the
Full Text Available The Indian sub-continent remains one of the most populous areas of the world with an estimated population of 1.1 billion in India alone. This yields an estimated 24.5 million births per year and the birth prevalence of clefts is somewhere between 27,000 and 33,000 clefts per year. Inequalities exist, both in access to and quality of cleft care with distinct differences in urban versus rural access and over the years the accumulation of unrepaired clefts of the lip and palate make this a significant health care problem in India. In recent years the situation has been significantly improved through the intervention of Non Governmental Organisations such as SmileTrain and Transforming Faces Worldwide participating in primary surgical repair programmes. The cause of clefts is multi factorial with both genetic and environmental input and intensive research efforts have yielded significant advances in recent years facilitated by molecular technologies in the genetic field. India has tremendous potential to contribute by virtue of improving research expertise and a population that has genetic, cultural and socio-economic diversity. In 2008, the World Health Organisation (WHO has recognised that non-communicable diseases, including birth defects cause significant infant mortality and childhood morbidity and have included cleft lip and palate in their Global Burden of Disease (GBD initiative. This will fuel the interest of India in birth defects registration and international efforts aimed at improving quality of care and ultimately prevention of non-syndromic clefts of the lip and palate.
Verger, A.; Novelli, M.
This article raises some critical questions regarding the current global compact on education for development, represented by Education for All (EFA), and analyzes how its form and content are embedded in a neoliberal model of economic development. It also argues that this neoliberal embedding repre
Greene, Scott; Bao, Yongchuan
The Association to Advance Collegiate Schools of Business (AACSB) standards mandate knowledge of global and technology issues. Businesses desire employees with ability to analyze international markets and to be adept with technology. Taxpayers supporting public universities and organizations hiring business school graduates expect accountability…
Ademola Omobewaji Dasylva
Full Text Available This paper has to do with the challenges of globalization in modern Nigeria and the process of “culture education,” a terminology used to emphasize the peculiar means and methods of instruction by which a society imparts its body of values and mores in the pursuance and attainment of the society’s collective vision, aspirations, and goals. Within this framework, this paper examines the legacies of imperialism and colonization within the Nigerian educational system––particularly in reference to the teaching of folklore and oral tradition––including the destruction of indigenous knowledge systems and the continuing lack of adequate resources in African universities. The paper concludes by offering suggestions for a more fully synthesized indigenous and formal Nigerian educational system as a method of addressing postcolonial rupture.
Shiffman, Saul; Music, Edvin; Styn, Mindi A; Kriska, Andrea; Smailagic, Asim; Siewiorek, Daniel; Ewing, Linda J; Chasens, Eileen; French, Brian; Mancino, Juliet; Mendez, Dara; Strollo, Patrick; Rathbun, Stephen L
the 12-month study interval, adherence to completing EMA surveys was high, with 88.3% (66,978/75,888) completion of random assessments and around 90% (23,411/25,929 and 23,343/26,010) completion of time-contingent assessments, despite the duration of EMA data collection and challenges with implementation. Conclusions This work informed us of the necessary preliminary steps to plan and prepare a longitudinal study using smartphone technology and the critical elements to ensure participant engagement in the potentially burdensome protocol, which spanned 12 months. While this was a technology-supported and -programmed study, it required close oversight to ensure all elements were functioning correctly, particularly once human participants became involved. PMID:28298264
Baumert, Thomas F; Schuster, Catherine; Cosset, François-Loïc; Dubuisson, Jean; Hofmann, Maike; Tautz, Norbert; Zeisel, Mirjam B; Thimme, Robert
Following the discovery of the hepatitis C virus (HCV) more than 25 years ago the field has succeeded to develop methods that have changed the safety of blood products, understand the molecular virology, epidemiology and clinical disease of HCV, and identify specific targets for the development of direct-acting antivirals for HCV cure. Nevertheless, major clinical and scientific challenges remain: therapy is still only available to a fraction of infected patients worldwide and many patients remain undiagnosed and/or live in countries where therapy is unattainable. An urgently needed HCV vaccine to eradicate infection remains still elusive. Scientifically, major questions remain regarding the life cycle, pathogenesis and mechanisms of viral clearance and persistence. Addressing these challenges, this meeting report reviews key findings of the 22nd International Symposium on Hepatitis C Virus and Related Viruses in Strasbourg, France from October 9 to 13, 2015.
Hood, Leroy E; Omenn, Gilbert S; Moritz, Robert L; Aebersold, Ruedi; Yamamoto, Keith R; Amos, Michael; Hunter-Cevera, Jennie; Locascio, Laurie
This White Paper sets out a Life Sciences Grand Challenge for Proteomics Technologies to enhance our understanding of complex biological systems, link genomes with phenotypes, and bring broad benefits to the biosciences and the US economy. The paper is based on a workshop hosted by the National Institute of Standards and Technology (NIST) in Gaithersburg, MD, 14-15 February 2011, with participants from many federal R&D agencies and research communities, under the aegis of the US National Science and Technology Council (NSTC). Opportunities are identified for a coordinated R&D effort to achieve major technology-based goals and address societal challenges in health, agriculture, nutrition, energy, environment, national security, and economic development.
Full Text Available Urban history is a very lively and dynamic research field, showing strict parallelism with the fast increasing of the urban population. Today, competitiveness is one of the key aims for cities in the globalized world. Factors such as accessibility and infrastructure, industry, human capital, innovation, and investment, green spaces, affordable housing, business support and quality of education are necessaries. However, the OECD recognizes three dilemmas in this strategic vision, concerning the spill over of metro-regions, the public strategic vision, and the relationship between economic dynamism and the liveable city. Today urban historians are facing some general challenges: comparative aspects are needed; also interdisciplinarity to develop cooperation between disciplines; and for maintaining the professional status of academic urban history. The expanding networks between towns and cities, and the meeting places as conferences and exhibitions are considered, as they are the multitudinous challenges and threats, especially for those cities suffering continuously of major natural and man-made disasters. Moreover, new amalgams of hazard are being created in metropolitan areas with overlapping natural, technological, biological and social risks, exposing more people and places, needing safety and security.
La historia urbana es un campo de investigación muy vivo y dinámico, mostrando un paralelismo estricto con el rápido incremento de la población urbana. La competencia es hoy uno de los objetivos claves para las ciudades en el mundo globalizado. Factores tales como la accesibilidad y las infraestructuras, la industria, el capital humano, la innovación y la inversión, los espacios verdes, la vivienda accesible, el apoyo a los negocios y la calidad de la educación son necesarios. Sin embargo, la OCDE reconoce tres dilemas en esa visión estratégica, el desarrollo de las metrópolis, la visión estratégica pública y la relaci
Keown, Oliver P; Warburton, Will; Davies, Sally C; Darzi, Ara
Antimicrobial therapies have played an unquestionably important role in advancing modern medical and surgical care, treating animals, reducing the global burden of communicable disease, and prolonging human life expectancy. These transformational benefits are threatened because of the rapidly advancing phenomenon of antimicrobial resistance. As a result of complex factors across many sectors and international actors, the global impact of antimicrobial resistance is an escalating economic and health crisis. This article draws on the collective expertise and summit report of the Antimicrobial Resistance Working Group from the 2013 World Innovation Summit for Health, in Doha, Qatar. It defines a framework of principles and tasks for key policy makers to raise international awareness of antimicrobial resistance and lead transformative action through policy-driven improvements in sanitation, antimicrobial conservation, agricultural practices, and research and development.
he recent Ebola crisis has caused approximately 20.000 deaths so far. Compared to other global health crises, including the deaths caused by armed conflicts and chronic diseases, this is still a small amount. Yet, from a global and domestic health law and governance perspective, this crisis raises a
The article deals with the issues of impact of globalization on population health and public health. The positive and negative aspects of this process are analyzed. The role of international organizations (UN, WHO, UNESCO, ILO, UNISEF) is demonstrated in the area of management of globalization impact on public health of different countries, Russia included.
Blair, Tony; Bardsley, Craig
Globalization continues to transform how universities work: the students and subjects they teach, and the way they conduct and disseminate research. With tight budgets everywhere in the wake of the global economic downturn, universities are under increasing pressure to demonstrate value for money to the wider public from their research and…
This article examines the relationship between globalization and postmodern multicultural art education. The questions that drive my investigation are: What is the role of postmodern multiculturalism in this current phase of globalization and what challenges does globalization pose for multiculturalism? I explore the shifts in the field of art…
Polack, Robert J.
The globalization of the economy creates new challenges for social work in the arenas of social and economic justice. This article outlines social justice issues related to the debt crisis of the Global South and sweatshops. A presentation of colonial precursors is followed by a detailed examination of these global institutions with an emphasis on…
Kraak, Vivica I; Kumanyika, Shiriki K; Story, Mary
Public- and private-sector initiatives to promote healthy eating and physical activity, called 'healthy lifestyles', are a relatively recent response to the global obesity pandemic. The present paper explores different views about marketing healthy lifestyles with a special emphasis on private-sector initiatives and public-private partnerships designed to reach young people. We discuss aspects of these initiatives and partnerships from three perspectives: (i) the potential for commercial marketing practices to have a favourable influence on reversing global obesity trends (termed prospects); (ii) unresolved dilemmas and challenges that may hinder progress (termed pitfalls); and (iii) the implementation and evaluation of coordinated and systematic actions (termed priorities) that may increase the likelihood that commercially marketed healthy-lifestyle initiatives and public-private partnerships can make a positive contribution to reverse the rise in overweight and obesity among young people globally.
In recent decades, there has seen a dramatic expansion of global planted forest area and their great impact on human life. It is reported in Forest Resource Assessment 2010 that the current area of global planted forests is about 264 million ha, representing only 7% of the total forest area but able to meet the two thirds of the global demand for logs. Planted forests can not only provide timber, fiber, fuel and non-wood forest products, but also contribute to carbon sequestration, restoration of degraded l...
Mabogunje, Akin L.
Since the end of the second World War, the link between deepening poverty and environmental degradation has increased in visibility despite the efforts of the United Nations and other international agencies. Focuses on globalization, poverty, and the environment. (DDR)
James Winston Morris
Full Text Available The contemporary historical situation suggests fascinating parallels with that period of the 13th/7th century when the massive destruction of the Mongol invasions opened the way for popular new forms of Islamic life and practice that eventually spread Islam throughout Asia. Today, as in earlier periods of dramatic upheaval, we can witness those processes of inspiration and awakening that give rise to the spiritual pathways of future centuries, through each soul’s gradual discovery of its unique challenges and demands of ihsan.One way of describing this transformation, to use the Qur’anic language adapted by Ibn ‘Arabi, is in the terms of the process of spiritual realization (tahqīq by which people discover their guiding inner relationship to those divine qualities or “Names” that eventually come to deﬁne the meaning and purpose of their lives. Through our life long movement of service (‘ibda to the “Lord” (rabb constituted by each divine Name, the transformation of the soul follows a familiar, naturally ascending trajectory. It begins with a curiosity drawing us toward some particular dimension of the Real (al-Haqq; then a compelling striving leading to heightened discipline and awareness; and ultimately to the creative manifestation of that devotion through the appropriate means of teaching, communication, and new communities of fellow- seekers—the Qur’anic “servants of the All-Merciful”—that slowly emerge from this shared spiritual work of devotion, discovery and creative response. Here we point to some ways this process of civilizational renewal is unfolding around the world, focusing on three of the most far-reaching of those divine Names: the “servants of the All-Wise” (al-Hakīm, in their exploring and deciphering the inﬁnite Signs of God’s Wisdom “on the horizons”, in all of the sciences of nature and society; to those muhsinūn and “servants of the Beautiful” (al-Jamīl whose
Mackey, Tim K; Contreras, John T; Liang, Bryan A
In October 2013, a new international binding treaty instrument called the Minamata Convention on Mercury opened for signature in Minamata City, Japan, the site of arguably the worst public health and environmental disaster involving mercury contamination. The treaty aims to curb the significant health and environmental impacts of mercury pollution and includes provisions addressing the mining, export and import, storage, and waste management of products containing mercury. Importantly, a provision heavily negotiated in the treaty addresses the use of dental fillings using mercury amalgam, an issue that has been subject to decades of global controversy. Though use of dental amalgam is widespread and has benefits, concerns have been raised regarding the potential for human health risk and environmental damage from emissions and improper waste management. While the Minamata Convention attempts to address these issues by calling for a voluntary phase-down of dental amalgam use and commitment to other measures, it falls short by failing to require binding and measurable targets to achieve these goals. In response, the international community should begin exploring ways to strengthen the implementation of the dental amalgam treaty provisions by establishing binding phase-down targets and milestones as well as exploring financing mechanisms to support treaty measures. Through strengthening of the Convention, stakeholders can ensure equitable access to global oral health treatment while also promoting responsible environmental stewardship.
Smyth, Stuart J; Phillips, Peter W B; Kerr, William A
The announcement that the European Union (EU) had reached an agreement allowing Member States (MS) to ban genetically modified (GM) crops confirms that the EU has chosen to ignore the food security challenge issued to the world by the Food and Agriculture Organization of the United Nations (FAO) in 2009. The FAO suggests that agricultural biotechnology has a central role in meeting the food security challenge.
Lacirignola, Martino; Blanc, Philippe; Girard, Robin; Pérez-López, Paula; Blanc, Isabelle
In the life cycle assessment (LCA) context, global sensitivity analysis (GSA) has been identified by several authors as a relevant practice to enhance the understanding of the model's structure and ensure reliability and credibility of the LCA results. GSA allows establishing a ranking among the input parameters, according to their influence on the variability of the output. Such feature is of high interest in particular when aiming at defining parameterized LCA models. When performing a GSA, the description of the variability of each input parameter may affect the results. This aspect is critical when studying new products or emerging technologies, where data regarding the model inputs are very uncertain and may cause misleading GSA outcomes, such as inappropriate input rankings. A systematic assessment of this sensitivity issue is now proposed. We develop a methodology to analyze the sensitivity of the GSA results (i.e. the stability of the ranking of the inputs) with respect to the description of such inputs of the model (i.e. the definition of their inherent variability). With this research, we aim at enriching the debate on the application of GSA to LCAs affected by high uncertainties. We illustrate its application with a case study, aiming at the elaboration of a simple model expressing the life cycle greenhouse gas emissions of enhanced geothermal systems (EGS) as a function of few key parameters. Our methodology allows identifying the key inputs of the LCA model, taking into account the uncertainty related to their description.
In this study new free-trade agreements are discussed, which are based on the breaking down of tariff and technical barriers and normally exclude most of the poorest countries in the world. Considering the current context of economic globalization and its health impacts, seven controversial points of these treaties and their possible implications for global public health are presented, mainly regarding health equity and other health determinants. Finally, this research proposes a greater social and health professionals participation in the formulation and discussion of these treaties, and a deeper insertion of Brazil in this important international agenda.
Muir, Ryan T; Wang, Shelly; Warf, Benjamin C
OBJECTIVE Pediatric hydrocephalus is one of the most common neurosurgical conditions and is a major contributor to the global burden of surgically treatable diseases. Significant health disparities exist for the treatment of hydrocephalus in developing nations due to a combination of medical, environmental, and socioeconomic factors. This review aims to provide the international neurosurgery community with an overview of the current challenges and future directions of neurosurgical care for children with hydrocephalus in low-income countries. METHODS The authors conducted a literature review around the topic of pediatric hydrocephalus in the context of global surgery, the unique challenges to creating access to care in low-income countries, and current international efforts to address the problem. RESULTS Developing countries face the greatest burden of pediatric hydrocephalus due to high birth rates and greater risk of neonatal infections. This burden is related to more general global health challenges, including malnutrition, infectious diseases, maternal and perinatal risk factors, and education gaps. Unique challenges pertaining to the treatment of hydrocephalus in the developing world include a preponderance of postinfectious hydrocephalus, limited resources, and restricted access to neurosurgical care. In the 21st century, several organizations have established programs that provide hydrocephalus treatment and neurosurgical training in Africa, Central and South America, Haiti, and Southeast Asia. These international efforts have employed various models to achieve the goals of providing safe, sustainable, and cost-effective treatment. CONCLUSIONS Broader commitment from the pediatric neurosurgery community, increased funding, public education, surgeon training, and ongoing surgical innovation will be needed to meaningfully address the global burden of untreated hydrocephalus.
Full Text Available Abstract Background Mulago National Referral Hospital (MNRH, Uganda’s primary tertiary and teaching hospital, and Makerere University College of Health Sciences (MakCHS have a close collaborative relationship. MakCHS students complete clinical rotations at MNRH, and MakCHS faculty partner with Mulago staff in clinical care and research. In 2009, as part of a strategic planning process, MakCHS undertook a qualitative study to examine care and service provision at MNRH, identify challenges, gaps, and solutions, and explore how MakCHS could contribute to improving care and service delivery at MNRH. Methods Key informant interviews (n=23 and focus group discussions (n=7 were conducted with nurses, doctors, administrators, clinical officers and other key stakeholders. Interviews and focus groups were tape recorded and transcribed verbatim, and findings were analyzed through collaborative thematic analysis. Results Challenges to care and service delivery at MNRH included resource constraints (staff, space, equipment, and supplies, staff inadequacies (knowledge, motivation, and professionalism, overcrowding, a poorly functioning referral system, limited quality assurance, and a cumbersome procurement system. There were also insufficiencies in the teaching of professionalism and communication skills to students, and patient care challenges that included lack of access to specialized services, risk of infections, and inappropriate medications. Suggestions for how MakCHS could contribute to addressing these challenges included strengthening referral systems and peripheral health center capacity, and establishing quality assurance mechanisms. The College could also strengthen the teaching of professionalism, communication and leadership skills to students, and monitor student training and develop courses that contribute to continuous professional development. Additionally, the College could provide in-service education for providers on professionalism
Richard J. Zeckhauser
Full Text Available The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.
A holistic view of long-term sustainability cannot ignore humanity’s ever-growing demands on fossil fuels, water, and other finite geological resources. Figure 1 (Princiotta et. al., 2014) illustrates the key factors that are responsible for potentially unsustainable global impac...
The provision of food is undergoing radical transformations throughout the global community. Peter Oosterveer argues that, as a consequence, conventional national governmental regulations can no longer adequately respond to existing and emerging food risks and to environmental concerns. This book ex
Drug-resistant tuberculosis, in particular Multi-Drug Resistant (MDR-TB) is an increasing global concern and a major burden for some developing countries, especially the BRICS. It is assumed that every year roughly 350 000 new MDR-TB cases occur in the world, on average in 20.5% of TB patients that have been previously treated but also in 3.5% of persons that have never been on TB treatment before. The global distribution of cases is very heterogeneous and is now better understood thanks to a growing number of specific surveys and routine surveillance systems: incidence is much higher in southern Africa and in all countries formerly part of the USSR. Countries with weak health systems and previously inefficient TB control programs are highly vulnerable to MDR epidemics because program failures do help creating, maintaining and spreading resistances. Global response is slowly rolled out and diagnosis capacities are on the rise (mostly with genotypic methods) but adequate and successful treatment and care is still limited to a minority of global cases. From a public health perspective the MDR-TB growing epidemics will not be controlled merely by the introduction of few new antibiotics because it is also linked to patient's compliance and adequate case management supported by efficient TB program. In depth quality improvement will only be achieved after previous errors are thoroughly analyzed and boldly corrected.
Stubbs, C. W.; Tonry, J. L.
Photometric calibration is currently the dominant source of systematic uncertainty in exploiting type Ia supernovae to determine the nature of the dark energy. We review our ongoing program to address this calibration challenge by performing measurements of both the instrumental response function and the optical transmission function of the atmosphere. A key aspect of this approach is to complement standard star observations by using NIST-calibrated photodiodes as a metrology foundation for optical flux measurements. We present our first attempt to assess photometric consistency between synthetic photometry and observations, by comparing predictions based on a NIST-diode-based determination of the PanSTARRS-1 instrumental response and empirical atmospheric transmission measurements, with fluxes we obtained from observing spectrophotometric standards.
Stubbs, Christopher W
Photometric calibration is currently the dominant source of systematic uncertainty in exploiting type Ia supernovae to determine the nature of the dark energy. We review our ongoing program to address this calibration challenge by performing measurements of both the instrumental response function and the optical transmission function of the atmosphere. A key aspect of this approach is to complement standard star observations by using NIST-calibrated photodiodes as a metrology foundation for optical flux measurements. We present our first attempt to assess photometric consistency between synthetic photometry and observations, by comparing predictions based on a NIST-diode-based determination of the PanSTARRS-1 instrumental response and empirical atmospheric transmission measurements, with fluxes we obtained from observing spectrophotometric standards.
Ezeudu, F. O.; Nkokelonye, C. U.; Adigwe, J. C.
This paper reviewed the scientific contents in Igbo culture. Description of the Igbos who constitutes an ethnic group occupying southeastern Nigeria was made. It x-rayed the pre-colonial, colonial, and post-colonial culture of Igbo people and identified the scientific cultural activities, which can be harnessed to meet the challenges of modern day…
Moyer, Sonja S.
Change in education is not going away; instead, it seems to be increasing exponentially. Technology has been the catalyst, and the changes with the greatest impact on education are the location and size of the classroom. The challenges associated with these changes involve working with students from potentially an unlimited number of countries and…
EPA announced the availability of the final report, Aquatic Ecosystems and Global Change: The Challenges of conducting Multi-Stressor Global Change Vulnerability Assessments. This report investigates the issues and challenges associated with identifying, calculating, and ...
... AGENCY Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor... of Availability. SUMMARY: EPA is releasing a final report entitled, Aquatic Ecosystems, Water Quality... with identifying, calculating, and mapping indicators of the relative vulnerability of water...
Full Text Available Medical tourism is not a new concept, even though there is still no international consensus on the name of this phenomenon that is manifesting itself for thousands of years. It is defined by moving patients in various countries to obtain medical care and combined with certain tourist facilities. Increased flow of patients seeking treatment abroad is a global phenomenon linked to economic growth which generates income revenue and a high level of education. Internationally, medical tourism increases by 20% per year, global market for medical tourism at present is estimated to be about 100 billion dollars. This study tries to highlight a conceptual analysis of medical tourism, the targeting of medical tourism flows and major destinations and the proposed tourism development strategies based on the experience of several countries medical.
breadth and pace of innovation . We are now experiencing a global shift to a more level playing field among nations; demographics, economics, and...The country’s status included predominance in most fields of science and technology (S&T), as well as a phenomenal breadth and pace of innovation . We...capita and using PPP rates over the period 2005–2050. 13 The World in 2050: Beyond the BRICs —A Broader
Injuries and violence are a significant cause of mortality and physical disability. Injuries killed five million people worldwide each year . The level of this dilemma, however, differs significantly by age, sex, region and economic development . Globally, road traffic injury mortalities, self-inflicted injury mortality and interpersonal violence, war, drowning, and exposure to fire are the leading cause of deaths among people aged 15-44 years . This special issue aims to assess the ...
Mihai, Florin-Constatin; Gnoni, Maria-Grazia
International audience; Waste Electrical and Electronic Equipment management (E-waste or WEEE) is a crucial issue in the solid waste management sector with global interconnections between well-developed, transitional and developing countries. Consumption society and addiction to technology dictate the daily life in high and middle-income countries where population consumes large amounts of EEE products (electrical and electronic equipment) which sooner become e-waste. This fraction is a fast-...
Abstract In 2012, food insecurity is still a major global concern as 1 billion people are suffering from starvation, under-, and malnutrition, and the Food and Agriculture Organization of the United Nations (FAO) has concluded that we are still far from reaching millennium development goal (MDG) number 1: to halve extreme poverty and hunger by 2015. In sub-Saharan Africa, the number of people suffering from hunger is estimated at 239 million, and this figure could increase in the near future....
Over the last few years, a new generation of Chinese multinationals has set out to conquer global markets, featuring major international acquisitions that were unthinkable until very recently. This work seeks to analyze the nature of this emerging phenomenon, illustrating the reasons behind the international expansion of Chinese multinationals, the factors that facilitate and hinder this process, the entry modes that they use and the strategic implications for Western companies of their sudde...
Dai, Jing; Chiu, Helen F K; Hou, Zai-Jin; Caine, Eric D
BACKGROUND: The paper addressed a unique challenge for public health and community research in rural China, i.e., the very large percentage of young adults that comprises a highly mobile working population that has been an essential component of the country's economic transformation. Fluid local demographic patterns potentially have a substantial impact on sample representativeness and data validity. METHODS: This report is based upon a cross sectional survey with face-to-face interviews of residents aged 16-34 years in rural communities of Mianyang, Sichuan Province, China. Two waves of fieldwork and other strategies were adopted in response to recruitment challenges. RESULTS: 1654 of 3008 potential participants took part in the study; this constituted 98% of those individuals approached and 55% of the persons enumerated in the local household registration system (hukou). Analyses revealed substantial differences among those who were interviewed during September and October 2005, versus those seen during the Chinese Lunar New Year of 2006 when many migrant workers and students returned to their homes. Both groups together differed from those who were unavailable during either recruiting episode. DISCUSSION AND CONCLUSIONS: We discuss potential responses to associated methodological challenges, including, (1) permanent hukou mismatches; (2) temporary hukou mismatches; (3) difficulties faced by potential participants to fully understand the purpose of research, the informed consent process, and specific research questions; and (4) appreciation of the importance of local social networks, as they pertain in particular to rural China. These findings underscore that there may be a need to make "on-the-ground" adjustments to varying local conditions to maximize sample representativeness and data validity.
Tudor Cristian Ţiclău
Full Text Available Education and professional development is considered central issues in civil service development and public administration reform. While this may be true, the content of such programs bears equal influence in skill acquirement, which in turn, has an impact on managerial performance (Perry, 1989. The contemporary economic and social environment poses numerous and complex challenges to public leaders, who need to be equipped with the adequate set of skills and competencies in order to have a proper response. The present paper aims to find out the whether the current educational programs from the business field can be a solution for preparing the next generation of public (and private leaders. My argument is that the latest developments in public management reform (New Public Management, Good Governance and Public Entrepreneurship combined with new demands for effectiveness, efficiency and high quality public services could increase the relevance of such programs. In support for this I presented a series of research results that point to a set of common leadership challenges that transcend the public-private divide. Finally I explored the offerings of the top 5 MBA programs in the world to see whether this is reflected in their educational programs. Not surprisingly, three out of the five programs analysed offer dual degree programs that combine business and public management education as a solution for the leadership challenges that lay ahead.
Polack, Robert J
The globalization of the economy creates new challenges for social work in the arenas of social and economic justice. This article outlines social justice issues related to the debt crisis of the Global South and sweatshops. A presentation of colonial precursors is followed by a detailed examination of these global institutions with an emphasis on the vulnerability, disempowered status, and exploitation of poor people of the Global South. Connections with global inequities in wealth, income, and the distribution of resources are made explicit. The article explores domestic social justice problems as possible points of connection with these issues. Finally, the authors give recommendations for social work education, advocacy, and activism.
Full Text Available The most basic stochastic epidemic models are those involving global transmission, meaning that infection rates depend only on the type and state of the individuals involved, and not on their location in the population. Simple as they are, there are still several open problems for such models. For example, when will such an epidemic go extinct and with what probability (questions depending on the population being fixed, changing or growing? How can a model be defined explaining the sometimes observed scenario of frequent mid-sized epidemic outbreaks? How can evolution of the infectious agent transmission rates be modelled and fitted to data in a robust way?
Singh, Navin Kumar
This book presents evolving language education trends by drawing examples and case studies from around the world. Over the past few decades, significant economic and political changes have taken place around the world which have had a significant impact on language teaching and learning practices across the globe. With globalization, the focus of language education has shifted from monolingualism towards bilingualism and multilingualism, in that multilingual practices have become the norm rather than the exception in most parts of the world. This book brings together some of latest controversi
The article deals with analysis of challenges and objectives for higher education in the context of globalization: the forming of international labour market proves the fact that the process of international integration is affecting economy and technology as well as social and labour relations that are becoming more and more global. The…
Full Text Available This paper describes an approach to teaching ethical intercultural communication. This approach helps students become aware of their own ethnocentric attitudes and helps them move beyond those perspectives to develop a mindful approach to intercultural communication. The paper begins by introducing the concept of mindful communication and the challenges of developing of a code of ethical behavior for communicating across cultures. Then, strategies for reconciling cultural relativism and universalism are offered. Finally, the paper provides a set of guidelines for ethical behavior in intercultural encounters.
Full Text Available The global market for oilseeds, grains, vegetable oil and oilseed meal is a complex market which is growing at a very fast pace, and which is characterized by the large volume of production which is traded between countries. Offer is geographically constrained in this market: there are few exporting countries and these are mainly situated on the American continent. Demand on the other hand is more widespread, although highest in Asiatic countries, China in particular. As a result, small importing countries, like Morocco, are in a vulnerable position, and take the full brunt of price volatility. In the 90s, Moroccan oilseed production was relatively high, unfortunately production dropped over the years, and Morocco must now buy vegetable oil and proteins on the global market. Reviving oilseed production in Morocco would considerably help the country and provide numerous benefits, such as food security, improving the country’s trade balance, and enhancing the agronomic management of land thanks to the introduction of break crops. Finally, it would also boost the entire agricultural sector and help increase the income of farmers.
Full Text Available The Young Masters Programme provides young people around the worldwith a net–based global–local learning environment for sustainable development. The present study investigates certain aspects of the implementation of this programme in the secondary schools of a Swedish municipality, in the context of the Lund Calling project. The research focuses on critical abilities to act globally, referred to as “knowledge capabilities”, and how they relate to the implementation process of initiating global learning for sustainabledevelopment (GLSD. A phenomenographic approach and semi–structuredinterviews were used in the investigation of the experiences of secondary school pupils, teachers and headmasters who participated in the project. Participants’ experiences of the changes carried out are described in relation to examples of knowledge capabilities needed for GLSD. Critical knowledge capabilities found to have been developed through the implementation were: to take command, and to collaborate. Critical knowledge capabilities perceived asnecessary, but not developed through the programme were: to be prepared, to act in a transdisciplinary manner, and to lead for a holistic understanding.
Laura Cătălina PAȘCU
Full Text Available Geopolitics born at the end of the 19th century and reborn at the end of the 20th century, from the need to explain certain issues arising out of the general evolution of human society and the growing influence of permanent politico-economic changes on the human consciousness and the entire system of socio-political life and culture. Also, geopolitics gives us the opportunity to reflect on the manifestation and evolution of power relations within a particular historical period, to assess and track changes and trends in the current system of international relations, giving us indicators and analytical methods about the reality of international relations. The relations of competition versus cooperation between international actors have changed gradually in the 21st century; however, development cooperation can provide solutions or opportunities for defining global problems. Globalization creates a new framework in security and international relations also introduced the geo-economics perspectives to assumed new found geopolitical importance at the outset of the twenty-first century.
Ritchie, Rachael J; Guy, Ken; Philp, Jim C
Recent advances in science and technology are igniting new interest in marine biotechnology. Governments are recognizing the potential of marine biotechnology to provide solutions to grand global challenges of population health, food, and energy security and sustainable industry. This paper examines some of the challenges to and policy options for the development of marine biotechnology.
It is an open, but not unanswerable, question as to how much atmospheric CO2 is sequestered globally by vegetation fires. In this work I conceptualise the question in terms of the general CharXive Challenge, discuss a mechanism by which thermoconversion of biomass may regulate the global distribution of carbon between reservoirs, show how suppression of vegetation fires by human activities may increase the fraction of carbon in the atmospheric pool, and pose three specific CharXive Challenges of crucial strategic significance to our management of global carbon cycles.
Swenson, R. B [Santa Cruz, CA (United States)
Humanity faces imminent and serious global oil shortages. It is urgent that the solar energy community respond aggressively to fulfill its central role in the transition from a transitory fossil-fuel economy to a sustainable solar future. The intention here is to explain and quantify the oil shortfall, to validate the renewable option, and to calculate the rate at which the capacity of the renewable energy industry must accelerate to counteract the predictable oil deficit. [Spanish] La humanidad se enfrenta a una seria e inminente escasez mundial de petroleo. Es urgente que la comunidad de energia solar responda agresivamente para satisfacer su rol central en la transicion de una economia transitoria de combustibles fosiles a un futuro solar sustentable. La intencion aqui es la de explicar y cuantificar el deficit de petroleo para validar esta opcion renovable y para calcular la velocidad a la que la industria de la energia renovable debe acelerar para contrarrestar el predecible deficit del petroleo.
This paper explores the role media play in safeguarding cultural diversity, promoting cultural dialogue, facilitating the exercise of cultural rights,fostering cultural understanding and cultivating intercultural citizenship in the age of globalization. The paper highlights several interconnected leverage points: media content, practices, processes, ownership, education, structures, and policies. It argues that fostering cultural diversity in and through the media can go a long way toward bringing a civic discourse which favors tolerance and facilitates co-existence. It can contribute to the breaking down of cultural barriers, the initiation of cultural dialogues, the empowerment of marginalized groups, and the practice of good governance. At the same time, this paper argues, the celebration of difference does not preclude the valuation of a common cultural core or a common humanity which brings people together in spite of their differences.
Destot, Michel [ed.] [Depute de l' Isere, Assemblee Nationale, Paris (France)
This is the proceedings of the 2. parliamentary gathering on energy held on 14 October 1999. The document presents the talks by Mr Michel Destot (as special rapporteur of the Industry's budget in National Assembly) and Laurent Fabius, President of National Assembly, and Jean-Claude Gayssot, Minister of Equipment, Transport and Dwelling, at the opening session, three round tables, the colloquium synthesis and the closing session. The round tables addressed the following issues: - 1. International and long-term approach guided predominantly by energy demand; - 2. Energy solutions in the struggle against greenhouse effect; - 3. Challenges of opening the European energy market (internationalization and decentralization). At the first round table, Yves Martin, President of the technical section of General Council of Mines, structured his introductory report emphasizing the specific issues of three time horizons: the present, characterized by abundant energy offer; the horizon of 10 to 20 years, that of the energy suppliers which is orienting their investments; the horizon of more than half a century, corresponding to responses of far-reaching actions imposed by energy demand and which must be the object of governments' policies. Jean-Yves Le Deaut, deputy of Meurthe-et-Moselle discussed the risks of climate change, resources' exhaustion, nuclear power and the issue of developing the renewable energies. The problems raised by energy demand by the year 2050 to met the needs of an earth population of 9 billions were mentioned by Philippe Trepant, the president of French Union of oil industries. Energy problems from a globalization standpoint were discussed also by Benjamin Dessus, Director of Ecodev program of CNRS. Policy in the field of mastering greenhouse gas releases was mentioned in the talk by Michel Mousel, president of Inter-ministerial Mission for greenhouse effect. In the frame of 2. round table questions relating to energy management, renewable
Andersson, K.G. [NKS/Technical University of Denmark (Denmark); Andgren, K. [NKS/Vattenfall R and D (Sweden); Leino, K. [NKS/Fortum Power and Heat Oy (Finland); Magnusson, S. [NKS/Icelandic Radiation Safety Authority (Iceland); Physant, F. [NKS/FRIT, Roskilde (Denmark)
Based on the foundation of a common cultural and historical heritage and a long tradition of collaboration, NKS aims to facilitate a common Nordic view on nuclear and radiation safety. A common understanding of rules, practice and measures, and national differences in this context, is here an essential requirement. Problems can generally be tackled quicker, more efficiently, more consistently and at a lower cost through collaboration, bearing in mind that key competencies are not equally distributed in the different Nordic countries. For instance common Nordic challenges emerge in relation to nuclear installations, where nuclear power plants are in operation in Finland and Sweden, and research reactors have been operated in Denmark, Finland, Norway and Sweden. There is an obvious benefit in exchanging ideas and technologies in relation to plant operation, and since a number of reactors in different Nordic countries are under decommissioning, a collaborative benefit can also be realised in that context. Sweden also has a nuclear fuel production plant, and its collaboration with other Nordic nuclear installations can also be beneficial. Further, a number of large radiological installations are projected in Nordic areas (e.g., the MAX-LAB/MAX IV synchrotron radiation source and the European spallation source ESS), where Nordic organisations are collaborating in addressing, e.g., potential environmental implications. On the emergency preparedness side, the Fukushima accident in March 2011 was a reminder that large accidents at nuclear installations can lead to widespread radioactive contamination in the environment. In order to respond to nuclear or radiological emergencies, should they affect Nordic populations, it is necessary to maintain an operational emergency preparedness. By continuously improving detection, response and decision aiding tools while maintaining an informal collaborative network between relevant stakeholders in the Nordic countries (including
Full Text Available This article deals with an international project to establish the extent to which it is feasible to achieve a worldwide acceptance of the Principles of Cooperation among the NAFTA Countries together with the Guidelines Applicable to Court-to-Court Communications in Cross-Border Cases. This contribution explains the process whereby the American Law Institute and the International Insolvency Institute (1 developed principles of cooperation with regard to cross-border insolvency; (2 established acceptance of these principles in jurisdictions across the world, subject to any necessary local modifications; and (3 obtained the endorsement of leading domestic associations, courts, and other groups in those jurisdictions. This article may contribute to the development the South African cross-border insolvency law. The inclusion of the challenges of harmonisation of private international law is also contributing to current debate.
Geris, L; Guyot, Y; Schrooten, J; Papantoniou, I
The cell therapy market is a highly volatile one, due to the use of disruptive technologies, the current economic situation and the small size of the market. In such a market, companies as well as academic research institutes are in need of tools to advance their understanding and, at the same time, reduce their R&D costs, increase product quality and productivity, and reduce the time to market. An additional difficulty is the regulatory path that needs to be followed, which is challenging in the case of cell-based therapeutic products and should rely on the implementation of quality by design (QbD) principles. In silico modelling is a tool that allows the above-mentioned challenges to be addressed in the field of regenerative medicine. This review discusses such in silico models and focuses more specifically on the bioprocess. Three (clusters of) examples related to this subject are discussed. The first example comes from the pharmaceutical engineering field where QbD principles and their implementation through the use of in silico models are both a regulatory and economic necessity. The second example is related to the production of red blood cells. The described in silico model is mainly used to investigate the manufacturing process of the cell-therapeutic product, and pays special attention to the economic viability of the process. Finally, we describe the set-up of a model capturing essential events in the development of a tissue-engineered combination product in the context of bone tissue engineering. For each of the examples, a short introduction to some economic aspects is given, followed by a description of the in silico tool or tools that have been developed to allow the implementation of QbD principles and optimal design.
Carvalhais, Nuno; Thurner, Martin; Forkel, Matthias; Beer, Christian; Reichstein, Markus
The response of the global terrestrial carbon cycle to climate change and the associated climate-carbon feedback has been shown to be highly uncertain. Ultimately this response depends on how carbon assimilation by vegetation changes relatively to the effective mean turnover time of carbon in vegetation and soils. Consequently, these turnover times of carbon are expected to depend on vegetation longevity and relative allocation to woody and non-woody biomass, and to litter and soil organic matter decomposition rates, which depend on climate variables, but also soil properties, biological activity and chemical composition of the litter. Data oriented estimates of whole ecosystem carbon turnover rates (τ) are based on global datasets of carbon stocks and fluxes and used to diagnose the co-variability of τ with climate. The overall mean global carbon turnover time estimated is 23 years (with 95% confidence intervals between 19 and 30 years), showing a strong spatial variability ranging from 15 years in equatorial regions to 255 years at latitudes north of 75°N. This latitudinal pattern reflects the expected dependencies of metabolic activity and ecosystem dynamics to temperature. However, a strong local correlation of τ with mean annual precipitation patterns is at least as prevalent as the expected effect of temperature on the global patterns of τ. The comparing between observation-based estimates of τ with current state-of-the-art Earth system models shows a consistent latitudinal pattern but a significant underestimation bias of ˜36% globally. Models consistently show a stronger association of τ to temperature and do not reproduce the observed association to mean annual precipitation in different latitudinal bands. A further breakdown of τ focusing on forest background mortality also shows contrasting regional patterns to those of global vegetation models, suggesting that the treatment of plant mortality may be overly simplistic in different model
Full Text Available New generic top-level domain names (gTLDs are the highest level of domain names in the domain name system (DNS; their number has been restricted to twenty-two for several years, and ICANN has implemented restrictions on the ways in which they are operated. The new gTLD programme, proposed by the Internet Corporation for Assigned Names and Numbers (ICANN in early 2013, enables businesses and organisations to apply for their own customised top-level domain names, thereby greatly expanding their current number. ICANN’s move is the most recent controversial one in a subfield of DNS management and internet governance, already rife with political and economic controversies. What are the implications of this 'turn' to new gTLDs? This article attempts to outline them, and addresses the impact of the new gTLDs programme on Europe’s action-taking in the internet governance realm. The article also considers the likely impact of the new programme on ICANN’s governance and weight vis-à-vis other important internet governance actors.
Diffenbaugh, Noah S.; Krupke, Christian H.; White, Michael A.; Alexander, Corinne E.
It has been conjectured that global warming will increase the prevalence of insect pests in many agro-ecosystems. In this paper, we quantitatively assess four of the key pests of maize, one of the most important systems in North American grain production. Using empirically generated estimates of pest overwintering thresholds and degree-day requirements, along with climate change projections from a high-resolution climate model, we project potential future ranges for each of these pests in the United States. Our analysis suggests the possibility of increased winter survival and greater degree-day accumulations for each of the pests surveyed. We find that relaxed cold limitation could expand the range of all four pest taxa, including a substantial range expansion in the case of corn earworm (H. zea), a migratory, cold-intolerant pest. Because the corn earworm is a cosmopolitan pest that has shown resistance to insecticides, our results suggest that this expansion could also threaten other crops, including those in high-value areas of the western United States. Because managing significant additional pressure from this suite of established pests would require additional pest management inputs, the projected decreases in cold limitation and increases in heat accumulation have the potential to significantly alter the pest management landscape for North American maize production. Further, these range expansions could have substantial economic impacts through increased seed and insecticide costs, decreased yields, and the downstream effects of changes in crop yield variability.
Full Text Available Injuries and violence are a significant cause of mortality and physical disability. Injuries killed five million people worldwide each year . The level of this dilemma, however, differs significantly by age, sex, region and economic development . Globally, road traffic injury mortalities, self-inflicted injury mortality and interpersonal violence, war, drowning, and exposure to fire are the leading cause of deaths among people aged 15-44 years . This special issue aims to assess the magnitude of this problem, identify risk factors and explore prevention strategies to alleviate the burden of injuries and violence. There is a dire need to increase the knowledge of the extent of problem, and associated risk factors that needs to be targeted for prevention. Erosa et al., examined reports of verbal and physical abuse from family caregivers of adults with severe physical, neurological and developmental disabilities, and found that caregivers who reported some form of abuse reported significantly greater distress and burden than caregivers who did not report any abuse. Grice et al., found that reported histories of work-related physical assault and work-related threat were associated with elevated risks of current work-related physical assault. Ahmad, systematically reviewed and summarized current scientific knowledge on the use of interactive computer-assisted screening to detect intimate partner violence (IPV.
Bagautdinova Nailya G.
Full Text Available Kazan Federal University being the leading one in the Volga region has set a strategic goal of academic reputation and University authority growth to achieve a high level of international recognition. The article describes the measures that were implemented by University management to enter the list of world leading universities. Some tools that accompany and foster necessary transformation are described and the way to align strategic priorities and economists training programs development is analyzed. The paper considers Bachelor and Master Degree courses in Economics and Management reshaping and establishes connection between New Third Generation Educational Standard introduction into the system of higher education and the process of University integration into the global educational environment. The new competence-based paradigm and interdisciplinary approach are both considered as important steps to improve academic and research performance. The “road map” developed and implemented by University management team was used as a platform for content analysis of qualitative data via systematic examination and verification of projected indicators open for public consideration on the official University web-page.
Full Text Available Improved communication technology has seen growth in a convergence of global corporate activities. In an effort to improve their global operations many companies are implementing global information systems in particular Enterprise Resource Planning (ERP systems. Companies are faced with a number of complexities when implementing these systems in a single country and considerable research has been conducted on the critical success factors associated with ERP implementations. However very little research has been conducted on the issues associated with global implementations of ERP systems and in particular implementations within the Asian region. This research utilises industry presentations to identify challenges and best practice for global implementations from the Asian region. The challenges have been classified as either technological or cultural pertaining to particular countries. The identified factors provide a foundation for further investigation.
Singh, Pritika; Guleri, Rupam; Angurala, Amrita; Kaur, Kuldeep; Kaur, Kulwinder; Kaul, Sunil C.; Wadhwa, Renu
Withania somnifera is a highly valued medicinal plant in traditional home medicine and is known for a wide range of bioactivities. Its commercial cultivation is adversely affected by poor seed viability and germination. Infestation by various pests and pathogens, survival under unfavourable environmental conditions, narrow genetic base, and meager information regarding biosynthesis of secondary metabolites are some of the other existing challenges in the crop. Biotechnological interventions through organ, tissue, and cell culture provide promising options for addressing some of these issues. In vitro propagation facilitates conservation and sustainable utilization of the existing germplasms and broadening the genetic base. It would also provide means for efficient and rapid mass propagation of elite chemotypes and generating uniform plant material round the year for experimentation and industrial applications. The potential of in vitro cell/organ cultures for the production of therapeutically valuable compounds and their large-scale production in bioreactors has received significant attention in recent years. In vitro culture system further provides distinct advantage for studying various cellular and molecular processes leading to secondary metabolite accumulation and their regulation. Engineering plants through genetic transformation and development of hairy root culture system are powerful strategies for modulation of secondary metabolites. The present review highlights the developments and sketches current scenario in this field.
Mazzetti, Paolo; Nativi, Stefano; Santoro, Mattia; Boldrini, Enrico
The Group on Earth Observation (GEO) is a voluntary partnership of governments and international organizations launched in response to calls for action by the 2002 World Summit on Sustainable Development and by the G8 (Group of Eight) leading industrialized countries. These high-level meetings recognized that international collaboration is essential for exploiting the growing potential of Earth observations to support decision making in an increasingly complex and environmentally stressed world. To this aim is constructing the Global Earth Observation System of Systems (GEOSS) on the basis of a 10-Year Implementation Plan for the period 2005 to 2015 when it will become operational. As a large-scale integrated system handling large datasets as those provided by Earth Observation, GEOSS needs to face several challenges related to big data handling and big data infrastructures management. Referring to the traditional multiple Vs characteristics of Big Data (volume, variety, velocity, veracity and visualization) it is evident how most of them can be found in data handled by GEOSS. In particular, concerning Volume, Earth Observation already generates a large amount of data which can be estimated in the range of Petabytes (1015 bytes), with Exabytes (1018) already targeted. Moreover, the challenge is related not only to the data size, but also to the large amount of datasets (not necessarily having a big size) that systems need to manage. Variety is the other main challenge since datasets coming from different sensors, processed for different use-cases are published with highly heterogeneous metadata and data models, through different service interfaces. Innovative multidisciplinary applications need to access and use those datasets in a harmonized way. Moreover Earth Observation data are growing in size and variety at an exceptionally fast rate and new technologies and applications, including crowdsourcing, will even increase data volume and variety in the next future
I Nyoman Darma Putra
AbstractIn September and October 2013, only one week apart,Bali hosted two global events in the upper class markettourism resort Nusa Dua. The first event was the MissWorld beauty pageant, and the other one was the APECSummit. Thousands of journalists from all over the worldcovered these events. From a tourism marketing point ofview, these two prestigious events helped Bali boost itspopularity through global mass media. Historically, sincethe early phase of its development, Bali’s tourism ind...
Garces, M.; Chan, S.; Leo, C.; Garcia, S.; Vidal, B.
From East Asia to the United States and all over Europe, the nuclear re-birth is generating demands the training simulation vendors had not faced before. Companies involved in the planning, design, construction and operation of new plants increasingly require simulation tools to satisfy very different needs, all of them on a large scale: education and support of inexperienced newcomer staff, human factors analysis and control room design, e-learning, verification and validation of I and C systems or training and licensing of crews before the actual installations are complete. There is a full set of applications already available to the whole industry to satisfy these needs. End-user friendly Thunder Real-Time Executive (T-REX), poised to become the standard simulation platform for U.S. plants, makes it possible to provide full-scope simulator and simulator exercises to students and others on a memory stick or over the internet. AREVA EPR full-scope training simulator, based on the ALICES integrated object-oriented simulation environment, becomes an engineering simulator for the Flamanville 3 plant under construction in Normandy; the same will happen to the Taishan 1 and 2 simulators in Guangdong (China) while UniStar plans to apply this approach to the future EPR's to be built in the United States. SIREP PWR Basic Principle Simulator, with simplified models which can run on an ordinary PC, is used at GDF SUEZ offices in Brussels to implement their Nuclear Trainees Program. EDF Training Department chooses On-line Micro Simulation (MicroSel), which can be managed with Learning Management Systems, for classroom and stand-alone learning of the basic characteristics of French reactors. All these are examples of how extensive R and D and innovation programs implemented by the simulator providers, some of them under way here in Spain, will help to overcome some of the challenges of the current nuclear expansion.
Over the last decades the electronics industry and ICT Industry in particular has revolutionized the world: electrical and electronic products have become ubiquitous in today's life around the planet. After use, those products are discarded, sometimes after re-use cycles in countries different from those where they were initially sold; becoming what is commonly called e-waste. Compared to other traditional waste streams, e-waste handling poses unique and complex challenges. e-Waste is usually regarded as a waste problem, which can cause environmental damage and severe human health consequences if not safely managed. e-Waste contains significant amounts of toxic and environmentally sensitive materials and is, thus, extremely hazardous to humans and the environment if not properly disposed of or recycled. On the other hand, e-waste is often seen as a potential source of income for individuals and entrepreneurs who aim to recover the valuable materials (metals in particular) contained in discarded equipment. Recently, for a growing number of people, in developing countries in particular, recycling and separation of e-waste has become their main source of income. In most cases, this is done informally, with no or hardly any health and safety standards, exposing workers and the surrounding neighborhoods to extensive health dangers as well as leading to substantial environmental pollution. Treatment processes of e-waste aim to remove the hazardous components and recover as much reusable material (e.g. metals, glass and plastics) as possible; achieving both objectives is most desired. The paper discuss societal implications of proper e-waste management and key elements to be considered in the policy design at country level.
The complex challenges confronting humanity today point to the need for new thinking and new theory in the social sciences which overcomes the limitations of compartmentalized, sectoral concepts, strategies and policies and mechanistic approaches to living social systems. The World Academy of Art & Science is convening a consortium of leading institutions and thinkers from different sectors to contribute ideas for formulation of a cohesive framework capable of addressing global social challenges in their totality and complex interrelationships. The objective of my presentation will be to explore the potential for collaboration between the physical and social sciences to arrive at a more cohesive and effective framework by exploring a series of questions, including - - Is an integrated science of society possible that transcends disciplinary boundaries based on common underlying principles as we find in the natural sciences? - To what extent can principles of natural science serve as valid models and a...
Groisman, Pavel; Gutman, Garik; Gulev, Sergey; Maksyutov, Shamil; Qi, Jiaguo
During the past 12 years, the Northern Eurasia Earth Science Partnership Initiative (NEESPI) - an interdisciplinary program of internationally-supported Earth systems and science research - has addressed large-scale and long-term manifestations of climate and environmental changes over Northern Eurasia and their impact on the Global Earth system. With more than 1500 peer-reviewed journal publications and 40 books to its credit, NEESPI's activities resulted in significant scientific outreach. This created a new research realm through self-organization of NEESPI scientists in a broad research network, accumulation of knowledge while developing new tools (observations, models, and collaborative networks) and producing new, exciting results that can be applied to directly support decision-making for societal needs. This realm was summed up at the Synthesis NEESPI Workshop in Prague, Czech Republic (April 9-12, 2015) where it was decided to shift gradually the foci of regional studies in Northern Eurasia towards applications with the following major Science Question: " What dynamic and interactive change(s) will affect societal well-being, activities, and health, and what might be the mitigation and adaptation strategies that could support sustainable development and decision-making activities in Northern Eurasia?". To answer this question requires a stronger socio-economic component in the ongoing and future regional studies focused on sustainable societal development under changing climatic and environmental conditions, especially, under conditions when societal decision-making impacts and feeds back on the environment. This made the NEESPI studies closer to the ICSU research initiative "Future Earth". Accordingly, the NEESPI Research Team decided to reorganize in the nearest future NEESPI into "Northern Eurasia Future Initiative" (NEFI) and began development of its Programmatic White Paper (in preparation at the time of this abstract submission). The NEFI research
Tyagi, Pawan; Friebe, Edward; Baker, Collin
Addressing the challenges of using high-Curie temperature ferromagnetic (FM) electrodes is critical for molecular spintronics devices (MSDs) research. Two FM electrodes simultaneously chemically bonded with a thiol-functionalized molecule can produce novel MSDs to exploring new quantum mechanical phenomenon and computer technologies. For developing a commercially viable MSD, it is crucial to developing a device fabrication scheme that carefully considers FM electrodes' susceptibility to oxidation, chemical etching, and stress-induced deformations during fabrication and usage. This paper studies NiFe, an alloy extensively used in present-day memory devices and high-temperature engineering applications, as a candidate FM electrode for the fabrication of MSDs. Our spectroscopic reflectance studies show that NiFe oxidized aggressively after heating beyond 90 °C. The NiFe surfaces, aged for several months or heated for several minutes below 90 °C, exhibited remarkable electrochemical activity and were found suitable for chemical bonding with the thiol-functionalized molecular device elements. NiFe also demonstrated excellent etching resistance against commonly used solvents and lithography related chemicals. Additionally, NiFe mitigated the adverse effects of mechanical stress by subsiding the stress-induced deformities. A magnetic tunnel junction-based MSD approach was designed by carefully considering the merits and limitations of NiFe. The device fabrication protocol considers the safe temperature limit to avoiding irreversible surface oxidation, the effect of mechanical stresses, surface roughness, and chemical etching. This paper provides foundational experimental insights in realizing a versatile MSD allowing a wide range of transport and magnetic studies.
Andrzejewski Jr C
Full Text Available Chester Andrzejewski Jr,1 Darlene Cloutier,1 David Unold,2 Richard C Friedberg1 1Transfusion Medicine Services, Department of Pathology, Baystate Medical Center, Baystate Health, Springfield, MA, 2Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA Abstract: Throughout the history of hemotherapy (HT, various challenges and concerns have been encountered in its practical application. When viewed using a prismatic lens of history, recurrent themes regarding adverse HT sequelae separate and become apparent. These can be broadly classified into three categories: infectious, noninfectious, and administrative/logistical. Using the HT care map as a frame of reference along with its associated rites, we examine the contemporary spectrum of HT adverse events and concerns, and some approaches as to how these may be addressed from bedside and laboratory medicine biovigilance perspectives enhancing patient care and blood transfusion safety. Although our vantage point is from an academic community hospital venue, the issues and concerns identified are germane to many if not all transfusion-medicine practice environments. Included among the subjects we explore are patient/specimen identification issues, blood-management initiatives, unrecognized and/or unreported suspected transfusion reactions, transfusion-associated adverse pulmonary sequelae (including transfusion-related acute lung injury and transfusion-associated circulatory overload, expanded applications of electronic health records and issues regarding their “meaningful use” and interinstitutional “digital compatibilities”, biovigilance integration of electronic data networks within and between health care entities, and anticipated workforce contractions secondary to projected declines in the availability of qualified laboratory professionals. Cooperative initiatives between accreditation and regulatory entities, blood collectors and suppliers, hospital
Tyagi, Pawan, E-mail: firstname.lastname@example.org; Friebe, Edward; Baker, Collin [University of the District of Columbia, Department of Mechanical Engineering (United States)
Addressing the challenges of using high-Curie temperature ferromagnetic (FM) electrodes is critical for molecular spintronics devices (MSDs) research. Two FM electrodes simultaneously chemically bonded with a thiol-functionalized molecule can produce novel MSDs to exploring new quantum mechanical phenomenon and computer technologies. For developing a commercially viable MSD, it is crucial to developing a device fabrication scheme that carefully considers FM electrodes’ susceptibility to oxidation, chemical etching, and stress-induced deformations during fabrication and usage. This paper studies NiFe, an alloy extensively used in present-day memory devices and high-temperature engineering applications, as a candidate FM electrode for the fabrication of MSDs. Our spectroscopic reflectance studies show that NiFe oxidized aggressively after heating beyond ∼90 °C. The NiFe surfaces, aged for several months or heated for several minutes below ∼90 °C, exhibited remarkable electrochemical activity and were found suitable for chemical bonding with the thiol-functionalized molecular device elements. NiFe also demonstrated excellent etching resistance against commonly used solvents and lithography related chemicals. Additionally, NiFe mitigated the adverse effects of mechanical stress by subsiding the stress-induced deformities. A magnetic tunnel junction-based MSD approach was designed by carefully considering the merits and limitations of NiFe. The device fabrication protocol considers the safe temperature limit to avoiding irreversible surface oxidation, the effect of mechanical stresses, surface roughness, and chemical etching. This paper provides foundational experimental insights in realizing a versatile MSD allowing a wide range of transport and magnetic studies.
Michelle Renée Mozell
Full Text Available This paper explores the impact of climate change upon the global production of winegrapes and wine. It includes a review of the literature on the cause and effects of climate change, as well as illustrations of the specific challenges global warming may bring to the production of winegrapes and wine. More importantly, this paper provides some practical solutions that industry professionals can take to mitigate and adapt to the coming change in both vineyards and wineries.
Full Text Available In the modern world, everyone must recognize that it is nearly impossible to separate many domestic and international problems and managing international challenges will take the efforts of all nations. As a result, each and every person must think like a global citizen and practice mindfulness in daily life. Using the complex interdependence model as a basis for examining citizen diplomacy, this paper suggests ways that new media can be used to introduce students to a global perspective on the world. Further, it provides faculty members with a set of guidelines for structuring projects that task students with the challenge of taking positive action to effect political and societal change.
BODEN John Mark; CAGNIN CRISTIANO; CARABIAS BARCELO VICENTE; HAEGEMAN Karel; KÖNNÖLÄ Timo-Topias Totti
What will the world look like in 2025? What are the possible future disruptive global challenges? And how can the EU position itself to take an active role in shaping a response to them? This publication offers possible answers to these questions through the identification of three main challenges and potential responses to these, and concludes that the main policy issues to be considered at EU level are: policy alignment towards sustainability; social diversity and the use of ICT for citizen...
Tan Darrell HS
Full Text Available Abstract Background Although a grossly disproportionate burden of disease from HIV/AIDS, TB and malaria remains in the Global South, these infectious diseases have finally risen to the top of the international agenda in recent years. Ideal strategies for combating these diseases must balance the advantages and disadvantages of 'vertical' disease control programs and 'horizontal' capacity-building approaches. Discussion The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM represents an important step forward in the struggle against these pathogens. While its goals are laudable, significant barriers persist. Most significant is the pitiful lack of funds committed by world governments, particularly those of the very G8 countries whose discussions gave rise to the Fund. A drastic scaling up of resources is the first clear requirement for the GFATM to live up to the international community's lofty intentions. A directly related issue is that of maintaining a strong commitment to the treatment of the three diseases along with traditional prevention approaches, with the ensuing debates over providing affordable access to medications in the face of the pharmaceutical industry's vigorous protection of patent rights. Summary At this early point in the Fund's history, it remains to be seen how these issues will be resolved at the programming level. Nevertheless, it is clear that significant structural changes are required in such domains as global spending priorities, debt relief, trade policy, and corporate responsibility. HIV/AIDS, tuberculosis and malaria are global problems borne of gross socioeconomic inequality, and their solutions require correspondingly geopolitical solutions.
Full Text Available The empirical study explored the relationships between firms characteristics and perceived readiness level of Malaysian Institute of Accountants firm members in meeting globalization challenges. In general all respondents indicated low readiness level in penetrating the global market. Seeing that the services sector is growing tremendously during the recent decades, there is a great opportunity for businesses to increase the export services in the foreseeable future to match that of the developed countries. Thus the findings and recommendations of this study provided comprehensive empirical information for entrepreneurs especially those involve in financial sector to actively embark into the global market.
This paper explores some new challenges facing universities in a global multimediated Internet-based environment, as they seek alternative paradigms and options to remain true to their core business. At a time of rapid technological change, and contested, complex concepts associated with globalisation, knowledge is becoming a primary factor of…
Nichols, Barbara L
The following four articles are based on presentations delivered at Building Global Alliances V: The Challenges of Migration for Health Professional Women, held in Philadelphia on December 7-8, 2008 and hosted by CGFNS International (formerly the Commission on Graduates of Foreign Nursing Schools).
This paper examines the challenges faced by the Turkish higher education system and exposes the inequities and realities educators in a developing nation must struggle with as they try to find a prestigious spot in the knowledge-production industry. After a brief overview of the literature that illustrates how globalization penetrated into each…
... AGENCY Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor.... SUMMARY: EPA is announcing the release of the draft report titled, ``Aquatic Ecosystems, Water Quality... relative vulnerability of water quality and aquatic ecosystems, across the United States, to the...
Copland, Fiona; Garton, Sue; Burns, Anne
Drawing on data from a recent research international research project, this article focuses on the challenges faced by teachers of English to young learners against the backdrop of the global rise of English. A mixed-methods approach was used to obtain the data, including a survey, which was completed by 4,459 teachers worldwide, and case studies,…
J. W. Hofmeyr
Full Text Available The purpose of this article is to discuss the six big challenges which should be taken into consideration in addressing the issue of doing and writing church history in Africa. The thesis of the article is that these challenges are not taken into sufficient consideration by the outside world as from a Third World perspective. Experts in the field of writing church history, in general, have stated and clearly articulated that no history is ever easy to write. What makes it particularly difficult to write church history in Africa, are the different perspectives on the establishment of the church on our continent. What we have, are pieces of information that have been distorted by prejudice and bias as each generation came to be. Addressing these challenges will, however, help us to overcome certain barriers in our study of African church history.
Jacob Dahl Rendtorff
Full Text Available Recently, the developments of ethics and politics in the Arctic region have again become an issue for international discussion. One main issue is the problem of climate change and sustainability of the Arctic region. This problem is linked to the issue of exploitation of natural resources in the Arctic region, not at least in Greenland. Indeed, the general issue is how we should define ethics of the environment and sustainability as a general principle for the Arctic region. It is important to discuss what is at stake and how we define the problem in relation to the different participating stakeholders. This paper deals with these problems as a case for global ethics and it proposes a vision of ethical and political responsibility for sustainable development in order to deal with such problems.
Hemmeter, Mary Louise; Santos, Rosa Milagros; Ostrosky, Michaelene M.
This article presents results from a survey of faculty members from 2- and 4-year higher education programs in nine states that prepare teachers to work with preschool children. The purpose of the study was to determine how professors address content related to social-emotional development and challenging behaviors, how well prepared they believe…
Full Text Available The Planetary Boundaries (PB framework represents a significant advance in specifying the ecological constraints on human development. However, to enable decision-makers in business and public policy to respect these constraints in strategic planning, the PB framework needs to be developed to generate practical tools. With this objective in mind, we analyse the recent literature and highlight three major scientific and technical challenges in operationalizing the PB approach in decision-making: first, identification of thresholds or boundaries with associated metrics for different geographical scales; second, the need to frame approaches to allocate fair shares in the ‘safe operating space’ bounded by the PBs across the value chain and; third, the need for international bodies to co-ordinate the implementation of the measures needed to respect the Planetary Boundaries. For the first two of these challenges, we consider how they might be addressed for four PBs: climate change, freshwater use, biosphere integrity and chemical pollution and other novel entities. Four key opportunities are identified: (1 development of a common system of metrics that can be applied consistently at and across different scales; (2 setting ‘distance from boundary’ measures that can be applied at different scales; (3 development of global, preferably open-source, databases and models; and (4 advancing understanding of the interactions between the different PBs. Addressing the scientific and technical challenges in operationalizing the planetary boundaries needs be complemented with progress in addressing the equity and ethical issues in allocating the safe operating space between companies and sectors.
Roskams, Jane; Popović, Zoran
Global neuroscience projects are producing big data at an unprecedented rate that informatic and artificial intelligence (AI) analytics simply cannot handle. Online games, like Foldit, Eterna, and Eyewire-and now a new neuroscience game, Mozak-are fueling a people-powered research science (PPRS) revolution, creating a global community of "new experts" that over time synergize with computational efforts to accelerate scientific progress, empowering us to use our collective cerebral talents to drive our understanding of our brain.
Background Digital forms of direct-to-consumer pharmaceutical marketing (eDTCA) have globalized in an era of free and open information exchange. Yet, the unregulated expansion of eDTCA has resulted in unaddressed global public health threats. Specifically, illicit online pharmacies are engaged in the sale of purportedly safe, legitimate product that may in fact be counterfeit or substandard. These cybercriminal actors exploit available eDTCA mediums over the Internet to market their suspect products globally. Despite these risks, a detailed assessment of the public health, patient safety, and cybersecurity threats and governance mechanisms to address them has not been conducted. Discussion Illicit online pharmacies represent a significant global public health and patient safety risk. Existing governance mechanisms are insufficient and include lack of adequate adoption in national regulation, ineffective voluntary governance mechanisms, and uneven global law enforcement efforts that have allowed proliferation of these cybercriminals on the web. In order to effectively address this multistakeholder threat, inclusive global governance strategies that engage the information technology, law enforcement and public health sectors should be established. Summary Effective global “eHealth Governance” focused on cybercrime is needed in order to effectively combat illicit online pharmacies. This includes building upon existing Internet governance structures and coordinating partnership between the UN Office of Drugs and Crime that leads the global fight against transnational organized crime and the Internet Governance Forum that is shaping the future of Internet governance. Through a UNODC-IGF governance mechanism, investigation, detection and coordination of activities against illicit online pharmacies and their misuse of eDTCA can commence. PMID:24131576
Arnove, Robert F.
Examines challenges to comparative and international education in the areas of epistemological approaches, research methodology, philosophical considerations, and dissemination of findings; the field's contributions in questioning assumptions about school-society relationships, identifying the benefits and dangers of "borrowing" educational…
Kuyvenhoven, Arie; Molle, Willem
To the classical driving forces of migration such as poverty, oppression and war, yet another is being added: globalization. The trend toward globalization has created new opportunities for trade and investment. These have had positive implications for economic growth and living standards. However, they also confront developed and less developed countries (LCDs) with difficult policy choices. Developed Countries (DCs) have to find a compromise between competitiveness and high labour costs, and between trade liberalization and immigration controls. LCDs have to decide whether to export labour or goods, and to accept foreign resources for development rather than migration. While, in the literature, the impact of globalization has been largely studied from specialist perspectives, this volume offers a comprehensive view of the issue. In Globalization of Labour Markets: Challenges, Adjustment and Policy Response in the European Union and Less Developed Countries international experts: Explain the welfare implicat...
CORALIA EMILIA POPA
Full Text Available This paper aims to present recent evolution, but also the consequences of globalization of the banking sector, considering different approaches of this phenomenon. Over time, the banking field has undergone important changes in both the applicable law of this area, and through the technologies used in satisfying the customers’ needs. The development of international markets has led to new opportunities and challenges for banks that transformed the domestic financial market into an arena where only the best survive and grow. On these grounds and in strict relation to positive and negative effects of globalization, we can speak of a constant evolution of its most important subsystems - the financial subsystems of the global economy. In this paper special importance is given to the banking field, the article presenting arguments through which this complex phenomenon called globalization may have important consequences on financial supervision and regulation.
The decommissioning of nuclear submarines, disposal of highly-enriched uranium and weapons-grade plutonium, and processing of high-level radioactive wastes represent the most challenging issues facing the cleanup of 20th century radiation legacy wastes and facilities. The US and Russia are the two primary countries dealing with these challenges, because most of the world's fissile inventory is being processed and stored at multiple industrial sites and nuclear weapons production facilities in these countries.
Orrell, Peter; Bennett, Alison E
Can above-belowground interactions help address issues of food security? We address this question in this manuscript, and review the intersection of above-belowground interactions and food security. We propose that above-belowground interactions could address two strategies identified by Godfray etal. (2010): reducing the Yield Gap, and Increasing Production Limits. In particular, to minimize the difference between potential and realized production (The Yield Gap) above-belowground interactions could be manipulated to reduce losses to pests and increase crop growth (and therefore yields). To Increase Production Limits we propose two mechanisms: utilizing intercropping (which uses multiple aspects of above-belowground interactions) and breeding for traits that promote beneficial above-belowground interactions, as well as breeding mutualistic organisms to improve their provided benefit. As a result, if they are managed correctly, there is great potential for above-belowground interactions to contribute to food security.
Bamidele A. OJO
Full Text Available This paper examines the question of distance education and its pivotal role in promoting social change and development in Africa. It also discussed within the context of the global digital divide and the ongoing need for collaborative effort at global education, the limitation imposed by the socio-economic and political environment on the continent. The paper in its findings conclude that the crisis within African societies constitutes a serious challenge to the implementation of and the effectiveness of distance education in Africa and therefore contributes to the widening of the digital divide rather than reducing it.
Öniş, Ziya; Yılmaz, Şuhnaz
TURKEY-US RELATIONS IN AN AGE OF REGIONAL AND GLOBAL TURMOIL: CHALLENGES AND PROSPECTS EDITORIAL INTRODUCTION Ziya Öniş and Şuhnaz Yılmaz This special issue on Turkish-American relations with a specific focus on the Middle East aims to analyze a complex web of relations at a critical regional and global juncture, with important implications well beyond bilateral relations. The idea for this special issue emerged during the “Turkish-American Alliance in a Volatile Region: ...
Parcover, Jason; Mays, Sally; McCarthy, Amy
The mental health needs of college students are placing increasing demands on counseling center resources, and traditional outreach efforts may be outdated or incomplete. The public health model provides an approach for reaching more students, decreasing stigma, and addressing mental health concerns before they reach crisis levels. Implementing a…
Bonner, Florence B.
Black women struggle for parity with men and white women in the U.S. academy. Examines gender issues at historically black colleges and universities (HBCUs), noting patterns of gender inequity and discrimination. These disparities are confounded by and in conflict with issues of race. Addresses the consequence of lack of attention to gender…
Hunter, Amy; Hemmeter, Mary Louise
The Center on the Social and Emotional Foundations for Early Learning (CSEFEL) is a federally funded national resource center designed to support early care and education providers address the social-emotional needs of children birth through age 5 years. Recent research has found that an extraordinarily high number of young children are being…
Globally, an estimated 24 percent of the disease burden (healthy life years lost) and an estimated 23 percent of all deaths (premature mortality) are attributable to environmental risks (World Health Organization, or WHO 2006). The burden of disease is unequally shared, with the children and the poor being particularly affected. Among children between the ages 0 and 14, the proportion of deaths ...
Jennifer Harris Requejo
Full Text Available Global monitoring of intervention coverage is a cornerstone of international efforts to improve reproductive, maternal, newborn, and child health. In this review, we examine the process and implications of selecting a core set of coverage indicators for global monitoring, using as examples the processes used by the Countdown to 2015 for Maternal, Newborn and Child Survival and the Commission on Accountability for Women's and Children's Health. We describe how the generation of data for global monitoring involves five iterative steps: development of standard indicator definitions and measurement approaches to ensure comparability across countries; collection of high-quality data at the country level; compilation of country data at the global level; organization of global databases; and rounds of data quality checking. Regular and rigorous technical review processes that involve high-level decision makers and experts familiar with indicator measurement are needed to maximize uptake and to ensure that indicators used for global monitoring are selected on the basis of available evidence of intervention effectiveness, feasibility of measurement, and data availability as well as programmatic relevance. Experience from recent initiatives illustrates the challenges of striking this balance as well as strategies for reducing the tensions inherent in the indicator selection process. We conclude that more attention and continued investment need to be directed to global monitoring, to support both the process of global database development and the selection of sets of coverage indicators to promote accountability. The stakes are high, because these indicators can drive policy and program development at the country and global level, and ultimately impact the health of women and children and the communities where they live.
Ford, Andrew Q; Touchette, Nancy; Hall, B Fenton; Hwang, Angela; Hombach, Joachim
The World Health Organization, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the Bill & Melinda Gates Foundation convened the first Global Vaccine and Immunization Research Forum (GVIRF) in March 2014. This first GVIRF aimed to track recent progress of the Global Vaccine Action Plan research and development agenda, identify opportunities and challenges, promote partnerships in vaccine research, and facilitate the inclusion of all stakeholders in vaccine research and development. Leading scientists, vaccine developers, and public health officials from around the world discussed scientific and technical challenges in vaccine development, research to improve the impact of immunization, and regulatory issues. This report summarizes the discussions and conclusions from the forum participants.
Hoffmann, Audrey N; Contreras, Bethany P; Clay, Casey J; Twohig, Michael P
Applied behavior analysts work with many populations including individuals with developmental and intellectual disabilities. Although behavior analysts have a variety of empirically supported treatments to implement when working with individuals with disabilities, sometimes, other variables may adversely impact treatment effectiveness. The degree to which problematic thoughts and feelings (private events) influence behavior may be a variable that contributes to treatment efficacy. Traditional behavior analytic services are not always equipped to successfully address the private events influencing client behavior. In such cases, it may be beneficial for behavior analysts to consider additional philosophically aligned treatments for private events. One such treatment, acceptance and commitment therapy, may be a useful tool for behavior analysts to incorporate into their toolbox in order to help clients. The purpose of this paper is to introduce behavior analysts to a potential solution to the problem of effectively addressing private events in behavior analytic services. We then propose a model for thinking about private events in relation to clients with disabilities and present a guide for taking steps to address private events in the clinical setting. We conclude this paper with a call for research and present a possible research agenda for behavior analysts.
Full Text Available In the context of an increasingly dynamic global society, adapting to new market conditions becomes a necessity, so that mutations in the tourism industry, as the economic sector to record the fastest ascent, become part of worldwide change. Tourism in the 21st century meets new dimensions as a result of unprecedented economic and technological expansion, the implications of these changes being profound and sometimes even difficult to explain or quantify. Therefore, defining an adequate tourism offer and adapting to market requirements become real challenges for economic agents, challenges that must be managed carefully in order to attain success. Currently, the focus is mainly on the technological factor and the sustainability of tourist activities, which become real progress binders, with strong influence on the entire supply chain. Global outlined trends define new ways to practice tourism, so that the technological evolution marks the transition of the entire travel experience from the offline to the online environment. The mobile segment is the one currently creating the newest opportunities for the development of tourist services, which is based on an increasingly close relationship between operators and tourists. It is to be seen whether Romania, as an emerging tourism market, which owns all necessary assets for a rapid and strong ascent, will be able to turn challenges offered by global dynamics into opportunities or will face the risks induced by it.
Barouch, Dan H; Stephenson, Kathryn E; Borducchi, Erica N; Smith, Kaitlin; Stanley, Kelly; McNally, Anna G; Liu, Jinyan; Abbink, Peter; Maxfield, Lori F; Seaman, Michael S; Dugast, Anne-Sophie; Alter, Galit; Ferguson, Melissa; Li, Wenjun; Earl, Patricia L; Moss, Bernard; Giorgi, Elena E; Szinger, James J; Eller, Leigh Anne; Billings, Erik A; Rao, Mangala; Tovanabutra, Sodsai; Sanders-Buell, Eric; Weijtens, Mo; Pau, Maria G; Schuitemaker, Hanneke; Robb, Merlin L; Kim, Jerome H; Korber, Bette T; Michael, Nelson L
The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development. HIV-1 mosaic antigens are bioinformatically optimized immunogens designed for improved coverage of HIV-1 diversity. However, the protective efficacy of such global HIV-1 vaccine antigens has not previously been evaluated. Here, we demonstrate the capacity of bivalent HIV-1 mosaic antigens to protect rhesus monkeys against acquisition of infection following heterologous challenges with the difficult-to-neutralize simian-human immunodeficiency virus SHIV-SF162P3. Adenovirus/poxvirus and adenovirus/adenovirus vector-based vaccines expressing HIV-1 mosaic Env, Gag, and Pol afforded a significant reduction in the per-exposure acquisition risk following repetitive, intrarectal SHIV-SF162P3 challenges. Protection against acquisition of infection correlated with vaccine-elicited binding, neutralizing, and functional nonneutralizing antibodies, suggesting that the coordinated activity of multiple antibody functions may contribute to protection against difficult-to-neutralize viruses. These data demonstrate the protective efficacy of HIV-1 mosaic antigens and suggest a potential strategy for the development of a global HIV-1 vaccine. PAPERCLIP:
Myers, J. D.
The Earth's seven billion humans are consuming a growing proportion of the world's ecosystem products and services. Human activity has also wrought changes that rival the scale of many natural geologic processes, e.g. erosion, transport and deposition, leading to recognition of a new geological epoch, the Anthropocene. Because of these impacts, several natural systems have been pushed beyond the planetary boundaries that made the Holocene favorable for the expansion of humanity. Given these human-induced stresses on natural systems, global citizens will face an increasing number of grand challenges. Unfortunately, traditional discipline-based introductory science courses do little to prepare students for these complex, scientifically-based and technologically-centered challenges. With NSF funding, an introductory, integrated science course stressing quantitative reasoning and social context has been created at UW. The course (GEOL1600: Global Sustainability: Managing the Earth's Resources) is a lower division course designed around the energy-water-climate (EWC) nexus and integrating biology, chemistry, Earth science and physics. It melds lectures, lecture activities, reading questionnaires and labs to create a learning environment that examines the EWT nexus from a global through regional context. The focus on the EWC nexus, while important socially and intended to motivate students, also provides a coherent framework for identifying which disciplinary scientific principles and concepts to include in the course: photosynthesis and deep time (fossil fuels), biogeochemical cycles (climate), chemical reactions (combustion), electromagnetic radiation (solar power), nuclear physics (nuclear power), phase changes and diagrams (water and climate), etc. Lecture activities are used to give students the practice they need to make quantitative skills routine and automatic. Laboratory exercises on energy (coal, petroleum, nuclear power), water (in Bangladesh), energy
Uauy, Ricardo; Corvalan, Camila; Dangour, Alan D
Optimal health and well-being are now considered the true measures of human development. Integrated strategies for infant, child and adult nutrition are required that take a life-course perspective to achieve life-long health. The major nutrition challenges faced today include: (a) addressing the pending burden of undernutrition (low birth weight, severe wasting, stunting and Zn, retinol, Fe, iodine and folic acid deficits) affecting those individuals living in conditions of poverty and deprivation; (b) preventing nutrition-related chronic diseases (obesity, diabetes, CVD, some forms of cancer and osteoporosis) that, except in sub-Saharan Africa, are the main causes of death and disability globally. This challenge requires a life-course perspective as effective prevention starts before conception and continues at each stage of life. While death is unavoidable, premature death and disability can be postponed by providing the right amount and quality of food and by maintaining an active life; (c) delaying or avoiding, via appropriate nutrition and physical activity interventions, the functional declines associated with advancing age. To help tackle these challenges, it is proposed that the term 'malnutrition in all its forms', which encompasses the full spectrum of nutritional disorders, should be used to engender a broader understanding of global nutrition problems. This term may prove particularly helpful when interacting with policy makers and the public. Finally, a greater effort by the UN agencies and private and public development partners is called for to strengthen local, regional and international capacity to support the much needed change in policy and programme activities focusing on all forms of malnutrition with a unified agenda.
Jones, Jenny; Thomson, Patricia; Lauder, William; Leslie, Stephen J
Reflexology is a complex massage intervention, based on the concept that specific areas of the feet (reflex points) correspond to individual internal organs within the body. Reflexologists trained in the popular Ingham reflexology method claim that massage to these points, using massage techniques unique to reflexology, stimulates an increase in blood supply to the corresponding organ. Reflexology researchers face two key methodological challenges that need to be addressed if a specific treatment-related hemodynamic effect is to be scientifically demonstrated. The first is the problem of inconsistent reflexology foot maps; the second is the issue of poor experimental controls. This article proposes a potential experimental solution that we believe can address both methodological challenges and in doing so, allow any specific hemodynamic treatment effect unique to reflexology to experimentally reveal itself.
Full Text Available This paper highlights the main consequences that the crisis has put on the European Union, regarding four major areas: financial, macroeconomic, social and mental-ideological. Also, it aims to tackle some key challenges for the European Union: the revival of international trade; the prevention of the rise of protectionism on the global scale; the need to find a solution to the dilemma between continued stimulus and financial consolidation in general, and between the ambitious goals of the Europe 2020 project and the current fiscal restrictions; the growth of public support across Europe for a financial consolidation strategy based on cutting spending; the impact of the financial and macroeconomic crisis on several sectors; and the deficiencies of the „European construction” indicated by the global crisis. Furthermore, it proposes four main questions for which EU has to provide clear answers in order to become a real global player. The questions concern the „European identity”, the „European values”, the EU strategy paper establishing its mission for the next period and the importance of a strong leadership implementing the strategy. In the end, the most important challenge seems to be how the EU can remain a global economic actor and become a more influential political player in the network of rapidly changing international power relations.
Marian Silviu Poboroniuc
Full Text Available The paper presents some results obtained through the implementation of the Erasmus LLP “SALEIE” (Strategic Alignment of Electrical and Information Engineering in European Higher Education Institutions. The aim of the project was to bring together experts from European universities to enhance the competitiveness of Electrical and Information Engineering (EIE education within Europe, especially in relation to modern global technical challenges and to provide higher education models in a few EIE fields in accordance with these challenges. One of the outcomes of the project was a new ICT (Information and Computer Technology Security curriculum for bachelor and master levels. The research methodology comprised such stages as: identifying the most important current global challenges, conducting a survey related to existing EIE programs in order to establish the top-level criteria for an EIE curriculum, analyzing the results of the survey, obtaining the industry feedback related to technical and non-technical skills required for the specific field, and proposing a new curriculum for ICT Security programmes to respond to the modern technical challenges and to meet the needs of the industry, students, academics and graduates. As future work we will focus on stakeholder assessment in the EIE field and, based on the resulting feedback, on improving the ICT Security curriculum.
Louw, Arnt Vestergaard
The findings of the expert group detail the role of youth work and its specific contribution to addressing the challenges young people face, in particular the transition from education to employment. In this context, youth work is defined as 'actions directed towards young people regarding activi...... activities where they take part voluntarily, designed for supporting their personal and social development through non-formal and informal learning'....
Advancements in technology, materials development, and manufacturing processes have changed the consumer products and composition of municipal solid waste (MSW) since 1960s. Increasing quantities of discarded consumer products remain a major challenge for recycling efforts, especially for discarded electronic products (also referred as e-waste). The growing demand for high tech products has increased the e-waste quantities and its cross boundary transport globally. This paper reviews the challenges associated with increasing e-waste quantities. The increasing need for raw materials (especially for rare earth and minor elements) and unregulated e-waste recycling operations in developing and underdeveloped counties contribute to the growing concerns for e-waste management. Although the markets for recycled materials are increasing; there are major challenges for development of the necessary infrastructure for e-waste management and accountability as well as development of effective materials recovery technologies and product design.
Ogburn, Sarah; Harpel, Chris; Pesicek, Jeremy; Wellik, Jay; Wright, Heather; Pallister, John
To prevent volcanic crises from becoming disasters, the USGS-USAID Volcano Disaster Assistance Program (VDAP) helps foreign counterparts to assess volcanic unrest, activity, and hazards before and during crises. Bayesian event trees are frequently used to facilitate discussion, reach consensus, evaluate uncertainty, and produce probabilistic forecasts of volcanic activity. VDAP uses a "method of multiple data sets" (Newhall & Pallister 2014), which combines conceptual and physical models of volcanic processes, current monitoring data, patterns of prior occurrence, and expert judgement from multiple disciplines to assign probabilities for each node of an event tree. The global volcanic record is used to inform our conceptual models, improve uncertainty estimates by leveraging larger datasets, and to fill in gaps where local information is sparse. For example, event trees for the recent Sinabung, Indonesia eruption relied upon local monitoring data-streams, but also on the global frequency-magnitude (VEI) of eruptions. A variety of databases are used, including the Smithsonian Institution's Global Volcanism Program (GVP) database, WOVOdat, GeoDIVA, DomeHaz, and FlowDat. Inhomogeneity and incompleteness of the global record present challenges for the use of such data in event trees, resulting in large and difficult to quantify uncertainties. Under-recording of small events, lack of documentation of 'failed eruptions', and variability of geophysical monitoring data-streams present particular problems. This contribution seeks to: (1) review VDAP's use of global data for probabilistic event tree creation; (2) summarize the problems presented by under-recording, spatial and temporal inhomogeneity, and incompleteness of the global record; (3) highlight ways to compensate for these effects, such as the development of hierarchical models to borrow strength from the global record while retaining local information, and the use of ranges in expert judgements to assess
Full Text Available The growth of computing technology during the previous three decades has resulted in a large amount of content being created in digital form. As their creators retire or pass away, an increasing number of personal data collections, in the form of digital media and complete computer systems, are being offered to the academic institutional archive. For the digital curator or archivist, the handling and processing of such digital material represents a considerable challenge, requiring development of new processes and procedures. This paper outlines how digital forensic methods, developed by the law enforcement and legal community, may be applied by academic digital archives. It goes on to describe the strategic and practical decisions that should be made to introduce forensic methods within an existing curatorial infrastructure and how different techniques, such as forensic hashing, timeline analysis and data carving, may be used to collect information of a greater breadth and scope than may be gathered through manual activities.
Chan, Brandford H Y; Leung, Gabriel M; Lau, Eric H Y; Pang, Herbert
Objectives To estimate the transmissibility of the Ice Bucket Challenge among globally influential celebrities and to identify associated risk factors. Design Retrospective cohort study. Setting Social media (YouTube, Facebook, Twitter, Instagram). Participants David Beckham, Cristiano Ronaldo, Benedict Cumberbatch, Stephen Hawking, Mark Zuckerberg, Oprah Winfrey, Homer Simpson, and Kermit the Frog were defined as index cases. We included contacts up to the fifth generation seeded from each index case and enrolled a total of 99 participants into the cohort. Main outcome measures Basic reproduction number R0, serial interval of accepting the challenge, and odds ratios of associated risk factors based on fully observed nomination chains; R0 is a measure of transmissibility and is defined as the number of secondary cases generated by a single index in a fully susceptible population. Serial interval is the duration between onset of a primary case and onset of its secondary cases. Results Based on the empirical data and assuming a branching process we estimated a mean R0 of 1.43 (95% confidence interval 1.23 to 1.65) and a mean serial interval for accepting the challenge of 2.1 days (median 1 day). Higher log (base 10) net worth of the participants was positively associated with transmission (odds ratio 1.63, 95% confidence interval 1.06 to 2.50), adjusting for age and sex. Conclusions The Ice Bucket Challenge was moderately transmissible among a group of globally influential celebrities, in the range of the pandemic A/H1N1 2009 influenza. The challenge was more likely to be spread by richer celebrities, perhaps in part reflecting greater social influence. PMID:25514905
Huesing, Joseph E; Andres, David; Braverman, Michael P; Burns, Andrea; Felsot, Allan S; Harrigan, George G; Hellmich, Richard L; Reynolds, Alan; Shelton, Anthony M; Jansen van Rijssen, Wilna; Morris, E Jane; Eloff, Jacobus N
Advances in biotechnology continue to drive the development of a wide range of insect-protected, herbicide-tolerant, stress-tolerant, and nutritionally enhanced genetically modified (GM) crops, yet societal and public policy considerations may slow their commercialization. Such restrictions may disproportionately affect developing countries, as well as smaller entrepreneurial and public sector initiatives. The 2014 IUPAC International Congress of Pesticide Chemistry (San Francisco, CA, USA; August 2014) included a symposium on "Challenges Associated with Global Adoption of Agricultural Biotechnology" to review current obstacles in promoting GM crops. Challenges identified by symposium presenters included (i) poor public understanding of GM technology and the need for enhanced communication strategies, (ii) nonharmonized and prescriptive regulatory requirements, and (iii) limited experience with regulations and product development within some public sector programs. The need for holistic resistance management programs to enable the most effective use of insect-protected crops was also a point of emphasis. This paper provides details on the symposium discussion and provides background information that can be used in support of further adoption of beneficial GM crops. Overall, it emphasizes that global adoption of modern agricultural biotechnology has not only provided benefits to growers and consumers but has great potential to provide solutions to an increasing global population and diminishing agricultural land. This potential will be realized by continued scientific innovation, harmonized regulatory systems, and broader communication of the benefits of the high-yielding, disease-resistant, and nutritionally enhanced crops attainable through modern biotechnology.
Yang, Weizhong; Liang, Xiaofeng; Cui, Fuqiang; Li, Li; Hadler, Stephen C; Hutin, Yvan J; Kane, Mark; Wang, Yu
During the China GAVI project, implemented between 2002 and 2010, more than 25 million children received hepatitis B vaccine with the support of project, and the vaccine proved to be safe and effective. With careful consideration for project savings, China and GAVI continually adjusted the budget, additionally allowing the project to spend operational funds to support demonstration projects to improve timely birth dose (TBD), conduct training of EPI staff, and to monitor the project impact. Results from the final evaluation indicated the achievement of key outcomes. As a result of government co-investment, human resources at county level engaged in hepatitis B vaccination increased from 29 per county on average in 2002 to 66 in 2009. All project counties funded by the GAVI project use auto-disable syringes for hepatitis B vaccination and other vaccines. Surveyed hepatitis B vaccine coverage increased from 71% in 2002 to 93% in 2009 among infants. The HBsAg prevalence declined from 9.67% in 1992 to 0.96% in 2006 among children under 5 years of age. However, several important issues remain: (1) China still accounts for the largest annual number of perinatal HBV infections (estimated 84,121) in the WHO WPR region; (2) China still lacks a clear national policy for safe injection of vaccines; (3) vaccination of high risk adults and protection of health care workers are still not implemented; (4) hepatitis B surveillance needs to be refined to more accurately monitor acute hepatitis B; and (5) a program for treatment of persons with chronic HBV infection is needed. Recommendations for future hepatitis B control include: using the lessons learned from the China GAVI project for future introductions of new vaccines; addressing unmet needs with a second generation hepatitis B program to reach every infant, including screening mothers, and providing HBIG for infants born to HBsAg positive mothers; expanding vaccination to high risk adults; addressing remaining unsafe
Joel Cracraft; Richard O' Grady
The symposium was held 10-12 May, 2007 at the Capitol Hilton Hotel in Washington, D. C. The 30 talks explored how some of today's key biological research developments (such as biocomplexity and complex systems analysis, bioinformatics and computational biology, the expansion of molecular and genomics research, and the emergence of other comprehensive or system wide analyses, such as proteomics) contribute to sustainability science. The symposium therefore emphasized the challenges facing agriculture, human health, sustainable energy, and the maintenance of ecosystems and their services, so as to provide a focus and a suite of examples of the enormous potential contributions arising from these new developments in the biological sciences. This symposium was the first to provide a venue for exploring how the ongoing advances in the biological sciences together with new approaches for improving knowledge integration and institutional science capacity address key global challenges to sustainability. The speakers presented new research findings, and identified new approaches and needs in biological research that can be expected to have substantial impacts on sustainability science.
Quissell, Kathryn; Walt, Gill
Where once global health decisions were largely the domain of national governments and the World Health Organization, today networks of international organizations, governments, private philanthropies and other entities are actively shaping public policy. However, there is still limited understanding of how global networks form, how they create institutions, how they promote and sustain collective action, and how they adapt to changes in the policy environment. Understanding these processes is crucial to understanding their effectiveness: whether and how global networks influence policy and public health outcomes. This study seeks to address these gaps through the examination of the global network to stop tuberculosis (TB) and the factors influencing its effectiveness over time. Drawing from ∼ 200 document sources and 16 interviews with key informants, we trace the development of the Global Partnership to Stop TB and its work over the past decade. We find that having a centralized core group and a strategic brand helped the network to coalesce around a primary intervention strategy, directly observed treatment short course. This strategy was created before the network was formalized, and helped bring in donors, ministries of health and other organizations committed to fighting TB-growing the network. Adaptations to this strategy, the creation of a consensus-based Global Plan, and the creation of a variety of participatory venues for discussion, helped to expand and sustain the network. Presently, however, tensions have become more apparent within the network as it struggles with changing internal political dynamics and the evolution of the disease. While centralization and stability helped to launch and grow the network, the institutionalization of governance and strategy may have constrained adaptation. Institutionalization and centralization may, therefore, facilitate short-term success for networks, but may end up complicating longer-term effectiveness.
Hoban, Sean; Vernesi, Cristiano
The study and practice of conservation biology is inherently interdisciplinary, addresses short and long time-scales and occurs within complex human-natural interfaces. Zoos and aquaria, in partnership with researchers, other non-government organizations, government, industry and educators, are combining knowledge of species and ecosystems with economics, psychology and law to create solutions for conserving biodiversity. From 22 to 25 May, the Conservation Forum of the European Association of Zoos and Aquaria was a venue for discussing conservation research, education and interventions, from the scale of villages to global policy.
Brauch, Hans Guenter [Freie Univ. Berlin (Germany). Dept. of Political and Social Sciences; Oswald Spring, Ursula [National Univ. of Mexico (UNAM), Mexico City (MX). Centro Regional de Investigaciones Multidisciplinarias (CRIM); Mesjasz, Czeslaw [Cracow Univ. of Economics (Poland). Faculty of Management; Grin, John [Amsterdam Univ. (Netherlands). Dept. of Political Science; Dunay, Pal [Geneva Centre for Security Policy (Switzerland); Chadha Behera, Navnita [Jamia Millia Islamia Univ., New Delhi (India). Nelson Mandela Center for Peace and Conflict Resolution; Chourou, Bechir [Univ. of Tunis-Carthage, Hammam-Chatt (Tunisia); Kameri-Mbote, Patricia [Nairobi Univ. (Kenya), Dept. of Private Law; Liotta, P.H. (eds.) [Salve Regina Univ., Newport, RI (United States). Pell Center for International Relations and Public Policy
Put quite simply, the twin impacts of globalization and environmental degradation pose new security dangers and concerns. In this comprehensive new work on global security thinking, 91 authors from five continents and many disciplines, from science and practice, assess the worldwide reassessment of the meaning of security triggered by the end of the Cold War and globalization, as well as the multifarious impacts of global environmental change in the early 21st century. Chapters address the theoretical, philosophical, ethical and religious and spatial context of security. They analyze the relationship between security, peace, development and environment. The authors move on to review the rethinking of security in international law, economics and political science, as well as in the key political, military and economic milieux. The book also examines the environmental security dimension and the adaptation of the institutional security concepts of the UN, EU and NATO, and analyzes the effect of change on regional security. Finally, it posits alternative security futures and draws conclusions for future research and action. (orig.)
Bishop, Thomas W; Gorniewicz, James; Floyd, Michael; Tudiver, Fred; Odom, Amy; Zoppi, Kathy
This workshop demonstrated the utility of a patient-centered web-based/digital Breaking Bad News communication training module designed to educate learners of various levels and disciplines. This training module is designed for independent, self-directed learning as well as group instruction. These interactive educational interventions are based upon video-recorded patient stories. Curriculum development was the result of an interdisciplinary, collaborative effort involving faculty from the East Tennessee State University (ETSU) Graduate Storytelling Program and the departments of Family and Internal Medicine at the James H. Quillen College of Medicine. The specific goals of the BBN training module are to assist learners in: (1) understanding a five-step patient-centered model that is based upon needs, preferences, and expectations of patients with cancer and (2) individualizing communication that is consistent with patient preferences in discussing emotions, informational detail, prognosis and timeline, and whether or not to discuss end-of-life issues. The pedagogical approach to the training module is to cycle through Emotional Engagement, Data, Modeled Practices, Adaptation Opportunities, and Feedback. The communication skills addressed are rooted in concepts found within the Reaching Common Ground communication training. A randomized control study investigating the effectiveness of the Breaking Bad News module found that medical students as well as resident physicians improved their communication skills as measured by an Objective Structured Clinical Examination. Four other similarly designed modules were also created: Living Through Treatment, Transitions: From Curable to Treatable/From Treatable to End-of-Life, Spirituality, and Family.
Ackleson, S. G.
Ocean observatories (systems of coordinated sensors and platforms providing real-time in situ observations across multiple temporal and spatial scales) have advanced rapidly during the past several decades with the integration of novel hardware, development of advanced cyber-infrastructures and data management software, and the formation of researcher networks employing fixed, drifting, and mobile assets. These advances have provided persistent, real-time, multi-disciplinary observations representing even the most extreme environmental conditions, enabled unique and informative views of complicated ocean processes, and aided in the development of more accurate and higher fidelity ocean models. Combined with traditional ship-based and remotely sensed observations, ocean observatories have yielded new knowledge across a broad spectrum of earth-ocean scales that would likely not exist otherwise. These developments come at a critical time in human history when the demands of global population growth are creating unprecedented societal challenges associated with rapid climatic change and unsustainable consumption of key ocean resources. Successfully meeting and overcoming these challenges and avoiding the ultimate tragedy of the commons will require greater knowledge of environmental processes than currently exists, including interactions between the ocean, the overlying atmosphere, and the adjacent land and synthesizing new knowledge into effective policy and management structures. To achieve this, researchers must have free and ready access to comprehensive data streams (oceanic, atmospheric, and terrestrial), regardless of location and collection system. While the precedent for the concept of free and open access to environmental data is not new (it traces back to the International Geophysical Year, 1957), implementing procedures and standards on a global scale is proving to be difficult, both logistically and politically. Observatories have been implemented in many
Cipcigan, Flaviu S; Crain, Jason; Martyna, Glenn J
One key factor that limits the predictive power of molecular dynamics simulations is the accuracy and transferability of the input force field. Force fields are challenged by heterogeneous environments, where electronic responses give rise to biologically important forces such as many-body polarisation and dispersion. The importance of polarisation was recognised early-on and described by Cochran in 1959 [Philosophical Magazine 4 (1959) 1082-1086]. However, dispersion forces are still treated at the two-body level and in the dipole limit, although the importance of three-body terms in the condensed phase was demonstrated by Barker in the 1980s [Phys. Rev. Lett. 57 (1986) 230-233]. A way of treating both polarisation and dispersion on an equal basis is to coarse grain the electrons a molecular moiety to a single quantum harmonic oscillator, as suggested as early as the 1960s by Hirschfelder, Curtiss and Bird [The Molecular Theory of Gases and Liquids (1954)]. This treatment, when solved in the strong coupling ...
Full Text Available England and Australia have introduced new learning areas, teaching computer science to children from the first year of school. This is a significant milestone that also raises a number of big challenges: the preparation of teachers and the development of resources at a national scale. Curriculum change is not easy for teachers, in any context, and to ensure teachers are supported, scaled solutions are required. One educational approach that has gained traction for delivering content to large-scale audiences are massively open online courses (MOOCs; however, little is known about what constitutes effective MOOC design, particularly within professional development contexts. To prepare teachers in Australia, we decided to ride the wave of MOOCs, developing a MOOC to deliver free computing content and pedagogy to teachers with the integration of social media to support knowledge exchange and resource building. The MOOC was designed to meet teacher needs, allowing for flexibility, ad-hoc interactions, support and the open sharing of resources. In this paper, we describe the process of developing our initiative, participant engagement and experiences, so that others encountering similar changes and reforms may learn from our experience.
Globalization is often referred to as external to education - a state of affair facing the modern curriculum with numerous challenges. In this paper it is examined as internal to curriculum; analysed as a problematization in a Foucaultian sense. That is, as a complex of attentions, worries, ways...... of reasoning, producing curricular variables. The analysis is made through an example of early childhood curriculum in Danish Pre-school, and the way the curricular variable of the pre-school child comes into being through globalization as a problematization, carried forth by the comparative practices of PISA...
Claeson, Björn Skorpen
Under the regime of private company or multi-stakeholder voluntary codes of conduct and industry social auditing, workers have absorbed low wages and unsafe and abusive conditions; labor leaders and union members have become the targets of both government and factory harassment and violence; and trade union power has waned. Nowhere have these private systems of codes and audits so clearly failed to protect workers as in Bangladesh's apparel industry. However, international labor groups and Bangladeshi unions have succeeded in mounting a challenge to voluntarism in the global economy, persuading more than 180 companies to make a binding and enforceable commitment to workers' safety in an agreement with 12 unions. The extent to which this Bangladesh Accord will be able to influence the entrenched global regime of voluntary codes and weak trade unions remains an open question. But if the Accord can make progress in Bangladesh, it can help to inspire similar efforts in other countries and in other industries.
Saltman Deborah C
Full Text Available Abstract Background In workforces that are traditionally mobile and have long lead times for new supply, such as health, effective global indicators of tertiary education are increasingly essential. Difficulties with transportability of qualifications and cross-accreditation are now recognised as key barriers to meeting the rapidly shifting international demands for health care providers. The plethora of mixed education and service arrangements poses challenges for employers and regulators, let alone patients; in determining equivalence of training and competency between individuals, institutions and geographical locations. Discussion This paper outlines the shortfall of the current indicators in assisting the process of global certification and competency recognition in the health care workforce. Using Organisation for Economic Cooperation and Development (OECD data we highlight how International standardisation in the tertiary education sector is problematic for the global health workforce. Through a series of case studies, we then describe a model which enables institutions to compare themselves internally and with others internationally using bespoke or prioritised parameters rather than standards. Summary The mobility of the global health workforce means that transportability of qualifications is an increasing area of concern. Valid qualifications based on workplace learning and assessment requires at least some variables to be benchmarked in order to judge performance.
Full Text Available bal Challenges in the Domestic Appliances IndustryAbstract: The domestic appliances industry is a mature industry. Changes in the business environment such as political, law, cultural, social, ecological and technological influences have an effect on the future development of this industry. Challenges to producers in this industry are oriented towards the further globalisation of the business, managing processes, new product and innovations development, and towards establishing and empowerment of the product brands. Global trends in the use of some natural sources, technological break-through, fulfilment of the market and strong competition direct us towards new innovations which will in their development consider also the social and environmental aspect as well.
Cipcigan, Flaviu S.; Sokhan, Vlad P.; Crain, Jason; Martyna, Glenn J.
One key factor that limits the predictive power of molecular dynamics simulations is the accuracy and transferability of the input force field. Force fields are challenged by heterogeneous environments, where electronic responses give rise to biologically important forces such as many-body polarisation and dispersion. The importance of polarisation in the condensed phase was recognised early on, as described by Cochran in 1959 [Philosophical Magazine 4 (1959) 1082-1086] . Currently in molecular simulation, dispersion forces are treated at the two-body level and in the dipole limit, although the importance of three-body terms in the condensed phase was demonstrated by Barker in the 1980s [Phys. Rev. Lett. 57 (1986) 230-233] . One approach for treating both polarisation and dispersion on an equal basis is to coarse grain the electrons surrounding a molecular moiety to a single quantum harmonic oscillator (cf. Hirschfelder, Curtiss and Bird 1954 [The Molecular Theory of Gases and Liquids (1954)] ). The approach, when solved in strong coupling beyond the dipole limit, gives a description of long-range forces that includes two- and many-body terms to all orders. In the last decade, the tools necessary to implement the strong coupling limit have been developed, culminating in a transferable model of water with excellent predictive power across the phase diagram. Transferability arises since the environment automatically identifies the important long range interactions, rather than the modeller through a limited set of expressions. Here, we discuss the role of electronic coarse-graining in predictive multiscale materials modelling and describe the first implementation of the method in a general purpose molecular dynamics software: QDO_MD.
Prosman, Ernst Johannes; Wæhrens, Brian Vejrum; Liotta, Giacomo
Replacing virgin materials with waste materials, a practice known as Industrial Symbiosis (IS), has been identified as a key strategy for closing material loops. This article adopts a critical view on geographic proximity and external coordinators – two key enablers of IS. By ‘uncovering’ a case ...... for geographic proximity and external coordinators. In doing so, our insights into firm-level challenges of long-distance IS exchanges contribute to closing global material loops by increasing the number of potential circular pathways....
Patricios, Jon S
Rugby Union (rugby) is a sport that evolved from and resembles other forms of football but is unique in many respects and presents distinctive clinical challenges. This article discusses those aspects of rugby that are different from other sports and those injuries that have specific significance to the game as a result of it being a global collision sport with an increasing focus on serious injury prevention. Injury screening and intervention programs, neck injuries, rugby's contribution to evolving concussion protocols, contact and travel-related illnesses, and rugby's drug intervention protocols are discussed.
Poboroniuc, Marian-Silviu; Friesel, Anna; Livint, Gheorghe
For the last two decades The European Association for Education in Electrical and Information Engineering (EAEEIE) has been dedicated and continue to support the Electrical and Information Engineering (EIE) education in Europe. SALEIE (Strategic Alignment of Electrical and Information Engineering......-of-the-art in implementation of the Bologna recommendation for Bachelor and Master, EIE connected technical, existing models in EIE higher education and their degree of response to key global technical challenges as well as some examples of curriculum models which see the day light during the SALEIE workshops...
David D. Hart
Full Text Available As the magnitude, complexity, and urgency of many sustainability problems increase, there is a growing need for universities to contribute more effectively to problem solving. Drawing upon prior research on social-ecological systems, knowledge-action connections, and organizational innovation, we developed an integrated conceptual framework for strengthening the capacity of universities to help society understand and respond to a wide range of sustainability challenges. Based on experiences gained in creating the Senator George J. Mitchell Center for Sustainability Solutions (Mitchell Center, we tested this framework by evaluating the experiences of interdisciplinary research teams involved in place-based, solutions-oriented research projects at the scale of a single region (i.e., the state of Maine, USA. We employed a multiple-case-study approach examining the experiences of three interdisciplinary research teams working on tidal energy development, adaptation to climate change, and forest vulnerability to an invasive insect. Drawing upon documents, observations, interviews, and other data sources, three common patterns emerged across these cases that were associated with more effective problem-solving strategies. First, an emphasis on local places and short-term dynamics in social-ecological systems research provides more frequent opportunities for learning while doing. Second, iterative stakeholder engagement and inclusive forms of knowledge co-production can generate substantial returns on investment, especially when researchers are dedicated to a shared process of problem identification and they avoid framing solutions too narrowly. Although these practices are time consuming, they can be accelerated by leveraging existing stakeholder relationships. Third, efforts to mobilize interdisciplinary expertise and link knowledge with action are facilitated by an organizational culture that emphasizes mutual respect, adaptability, and solutions
Myers, J. D.
GEOL1600: Global Sustainability: Managing the Earth's Resources is a lower division integrated science course at the University of Wyoming that fulfills the university's science requirement. Course content and context has been developed using the grand challenge nexus of energy-water-and climate (EWC). The interconnection of these issues, their social relevance and timeliness has provided a framework that gives students an opportunity to recognize why STEM is relevant to their lives regardless of their ultimate professional career choices. The EWC nexus provides the filter to sieve the course's STEM content. It also provides an ideal mechanism by which the non-STEM perspectives important in grand challenge solutions can be seamlessly incorporated in the course. Through a combination of content and context, the relevance of these issues engage students in their own learning. Development of the course followed the Grand Challenge Scientific Literacy (GCSL) model independently developed by the author and two colleagues at the University of Wyoming. This course model stresses science principles centered on the nature of science (e.g., fundamental premises, habits of mind, critical thinking) and unifying scientific concepts (e.g., methods and tools, experimentation, modeling). Grand challenge principles identify the STEM and non-STEM concepts needed to understand the grand challenges, drawing on multiple STEM and non-STEM disciplines and subjects (i.e., economics, politics, unintended consequences, roles of stakeholders). Using the EWC nexus filter and building on the Grand Challenge Principles, specific content included in the course is selected is that most relevant to understanding the Grand Challenges, thereby stressing content depth over breadth. Because quantitative data and reasoning is critical to effectively evaluating challenge solutions, QR is a component of nearly all class activities, while engineering and technology aspects of grand challenges are
Full Text Available Abstract Background Since 1995, approval for many new medicinal products has been obtained through a centralized procedure in the European Union. In recent years, the use of summary measures of population health has become widespread. We investigated whether efforts to develop innovative medicines are focusing on the most relevant conditions from a global public health perspective. Methods We reviewed the information on new medicinal products approved by centralized procedure from 1995 to 2009, information that is available to the public in the European Commission Register of medicinal products and the European Public Assessment Reports from the European Medicines Agency. Morbidity and mortality data were included for each disease group, according to the Global Burden of Disease project. We evaluated the association between authorized medicinal products and burden of disease measures based on disability-adjusted life years (DALYs in the European Union and worldwide. Results We considered 520 marketing authorizations for medicinal products and 338 active ingredients. New authorizations were seen to increase over the period analyzed. There was a positive, high correlation between DALYs and new medicinal product development (ρ = 0.619, p = 0.005 in the European Union, and a moderate correlation for middle-low-income countries (ρ = 0.497, p = 0.030 and worldwide (ρ = 0.490, p = 0.033. The most neglected conditions at the European level (based on their attributable health losses were neuropsychiatric diseases, cardiovascular diseases, respiratory diseases, sense organ conditions, and digestive diseases, while globally, they were perinatal conditions, respiratory infections, sense organ conditions, respiratory diseases, and digestive diseases. Conclusions We find that the development of new medicinal products is higher for some diseases than others. Pharmaceutical industry leaders and policymakers are invited to consider the implications of this
Romuladus E. Azuine, DrPH, RN
Full Text Available One year after the birth of the International Journal of MCH and AIDS (IJMA, we continue to share the passion to document, and shine the light on the myriads of global health issues that debilitate developing countries.Although the focus of IJMA is on the social determinants of health and disease as well as on the disparities in the burden of communicable and non-communicable diseases affecting infants, children, women, adults, and families in developing countries, we would like to encourage our fellow researchers and policy makers in both the developing and developed countries to consider submitting work that examines cross-national variations in heath and social inequalities.Such a global focus allows us to identify and understand social, structural, developmental, and health policy determinants underlying health inequalities between nations.Global assessment of health and socioeconomic patterns reaffirms the role of broader societal-level factors such as human development, gender inequality, gross national product, income inequality, and healthcare infrastructure as the fundamental determinants of health inequalities between nations.This is also confirmed by our analysis of the WHO data that shows a strong negative association between levels of human development and infant and maternal mortality rates.Focusing on socioeconomic, demographic, and geographical inequalities within a developing country, on the other hand, should give us a sense of how big the problem of health inequity is within its own borders.Such an assessment, then, could lead to development of policy solutions to tackle health inequalities that are unique to that country.
Imdad, Aamer; Bhutta, Zulfiqar A
Despite numerous advances and improvements in child health, malnutrition still remains as one of the main public health challenges of the 21st century, particularly in developing countries. It undermines the survival, growth and development of children, and is associated with almost 35% of all deaths in children under the age of 5 years worldwide. An estimated 178 million children are stunted globally, and an additional 19 million children have severe acute malnutrition (wasting). These conditions are very often associated with concomitant micronutrient deficiencies, and among these, vitamin A, iron, zinc and iodine deficiencies are the most prevalent in childhood. Vitamin A and zinc deficiency is associated with an estimated 1 million child deaths and 9% of global childhood disability-adjusted life years. Recent data on the timing of growth retardation and stunting in infants suggest that the onset is commensurate with inappropriate complementary feeding and potentially compounded by maternal undernutrition and intrauterine growth retardation, and that the first 24 months represent a critical window of opportunity for intervention. Given the wide prevalence of multiple micronutrient deficiencies in malnourished children in developing countries, the challenge is to implement intervention strategies that combine appropriate infant and young child feeding with micronutrient interventions at scale. Emerging data from community intervention trials now provide evidence that this is both tangible and can lead to alleviation of childhood undernutrition. Some of these recent findings will be discussed.
Full Text Available Developing a rigorous understanding of multiple global threats to species persistence requires the use of integrated modeling methods that capture processes which influence species distributions. Species distribution models (SDMs coupled with population dynamics models can incorporate relationships between changing environments and demographics and are increasingly used to quantify relative extinction risks associated with climate and land-use changes. Despite their appeal, uncertainties associated with complex models can undermine their usefulness for advancing predictive ecology and informing conservation management decisions. We developed a computationally-efficient and freely available tool (GRIP 2.0 that implements and automates a global sensitivity analysis of coupled SDM-population dynamics models for comparing the relative influence of demographic parameters and habitat attributes on predicted extinction risk. Advances over previous global sensitivity analyses include the ability to vary habitat suitability across gradients, as well as habitat amount and configuration of spatially-explicit suitability maps of real and simulated landscapes. Using GRIP 2.0, we carried out a multi-model global sensitivity analysis of a coupled SDM-population dynamics model of whitebark pine (Pinus albicaulis in Mount Rainier National Park as a case study and quantified the relative influence of input parameters and their interactions on model predictions. Our results differed from the one-at-time analyses used in the original study, and we found that the most influential parameters included the total amount of suitable habitat within the landscape, survival rates, and effects of a prevalent disease, white pine blister rust. Strong interactions between habitat amount and survival rates of older trees suggests the importance of habitat in mediating the negative influences of white pine blister rust. Our results underscore the importance of considering habitat
Full Text Available The article deals with analysis of challenges and objectives for higher education in the context of globalization: the forming of international labour market proves the fact that the process of international integration is affecting economy and technology as well as social and labour relations that are becoming more and more global. The peculiarities of structure (gradation, succession, multivectorability, continuity, content (narrow profile, sustainable development, competency-based orientation, specialization, curriculum flexibility, combination of core and optional subjects, possibility to choose courses and modules of different levels, forms (designing and modeling in small groups, workshops, practical intensive and extended learning, role playing, lectures, online sessions, problem-oriented excursions, seminars, internships and extended pedagogical placements in training of specialists at universities in European countries have been established. According to the project “Implementation and Influence of Curriculum Reforms in Higher Education in Europe” a competency-based approach is given much significance on the institutional level. Urgent objectives for higher education in Ukraine in the context of the return of emigrants to their home country, highly qualified specialists, in particular, is fast effective reforming of education based on practical orientation; appreciation of social phenomena in the context of their cultural values and the dynamics of society; global character of curricula (ethnocentrism, multiculturalism, interdisciplinarity, universality, innovativeness of international comparison and large potential for fulfilling needs in developing skills.
Full Text Available Published by Palgrave MacmillanThis chapter explores the thesis that the United Nations’ (UN most important contribution to the production of global public goods has been its role in creating the space and capacity to generate shared values. Starting with the UN Charter itself, the chapter traces the evolution of this contribution through different historical phases. It analyses the impact of globalisation on the role of the UN; in particular it identifies the quality of porousness as a product of globalisation which is critical to understanding the current challenges faced by the UN as well as central to the global public goods agenda. Through this lens the author briefly reviews the evolution of the UN’s role in the fields of peace and security, human rights and development cooperation. He concludes by identifying eight levers for change that will determine the UN’s ability to contribute significantly to the global public goods: the generation of norms and shared values, the quality of leadership, improved governance, innovative financing, institutional realignment, the further consolidation of legal instruments, focus, and the power of networks.
Guarneri, Erminia; King, Rauni Prittinen
Biofield therapies (BTs) are increasingly employed in contemporary healthcare. In this white paper, we review specific challenges faced by biofield practitioners resulting from a lack of (1) a common scientific definition of BT; (2) common educational standards for BT training (including core competencies for clinical care); (3) collaborative team care education in complementary and alternative medicine (CAM) and in integrative health and medicine (IHM); (4) a focused agenda in BT research; and (5) standardized devices and scientifically validated mechanisms in biofield research. We present a description of BT and discuss its current status and challenges as an integrative healthcare discipline. To address the challenges cited and to enhance collaboration across disciplines, we propose (1) standardized biofield education that leads to professional licensure and (2) interprofessional education (IPE) competencies in BT training required for licensed healthcare practitioners and encouraged for other practitioners using these therapies. Lastly, we discuss opportunities for growth and a potential strategic agenda to achieve these goals. The Academy of Integrative Health and Medicine (AIHM) provides a unique forum to facilitate development of this emerging discipline, to facilitate IPE, and to further increase the availability of BT to patients.
Paul M Macey
Full Text Available Obstructive sleep apnea (OSA is accompanied by brain injury, perhaps resulting from apnea-related hypoxia or periods of impaired cerebral perfusion. Perfusion changes can be determined indirectly by evaluation of cerebral blood volume and oxygenation alterations, which can be measured rapidly and non-invasively with the global blood oxygen level dependent (BOLD signal, a magnetic resonance imaging procedure. We assessed acute BOLD responses in OSA subjects to pressor challenges that elicit cerebral blood flow changes, using a two-group comparative design with healthy subjects as a reference. We separately assessed female and male patterns, since OSA characteristics and brain injury differ between sexes. We studied 94 subjects, 37 with newly-diagnosed, untreated OSA (6 female (age mean ± std: 52.1±8.1 yrs; apnea/hypopnea index [AHI]: 27.7±15.6 events/hr and 31 male 54.3±8.4 yrs; AHI: 37.4±19.6 events/hr, and 20 female (age 50.5±8.1 yrs and 37 male (age 45.6±9.2 yrs healthy control subjects. We measured brain BOLD responses every 2 s while subjects underwent cold pressor, hand grip, and Valsalva maneuver challenges. The global BOLD signal rapidly changed after the first 2 s of each challenge, and differed in magnitude between groups to two challenges (cold pressor, hand grip, but not to the Valsalva maneuver (repeated measures ANOVA, p<0.05. OSA females showed greater differences from males in response magnitude and pattern, relative to healthy counterparts. Cold pressor BOLD signal increases (mean ± adjusted standard error at the 8 s peak were: OSA 0.14±0.08% vs. Control 0.31±0.06%, and hand grip at 6 s were: OSA 0.08±0.03% vs. Control at 0.30±0.02%. These findings, indicative of reduced cerebral blood flow changes to autonomic challenges in OSA, complement earlier reports of altered resting blood flow and reduced cerebral artery responsiveness. Females are more affected than males, an outcome which may contribute to the sex
Full Text Available First suggested in the Netherlands, in the late-1980s, the notion of Social Movement Unionism was ?rst applied in South Africa, where it had both political and academic impact. The South-African formulation combined the class and the popular: a response to this combined class and new social movement theory/practice. The Class/Popular understanding was, however, more widely adopted, and applied (to and/or in Brazil, the Philippines, the USA, internationally, receiving its most in?uential formulation in the work of Kim Moody (USA. A Class/New Social Movement response to this was restated in terms of the New Social Unionism. The continuing impact of globalization and neo-liberalism has had a disorienting e?ect on even the unions supposed by the South African/USschool to best exemplify SMU, whilst simultaneously increasing trade union need for some kind of such an alternative model. Use and discussion of the notion continues. The development of the global justice and solidarity movement (symbolized by Seattle, 1999, and in particular the World Social Forum process, since 2001, may be putting the matter on the international trade-union agenda. But is this matter a Class/Popular alliance, a Class/New Social Movement alliance? Or both? Or something else? And are there other ways of recreating an international/ist labour movement with emancipatory intentions and e?ect? What is the future of emancipatory or utopian labour strategy in the epoch of a globalized networked capitalism, and the challenge of the Global Justice and Solidarity Movement?
@@ On behalf of the International Life Sciences Institute, I welcome you to Beijing and to the Third Asian Conference on Food Safety and Nutrition. Many of you will remember the first Asian conference on Food Safety held in Kuala Lumpur in 1990 and the second held in Bangkok in 1994. These meetings have been so successful that ILSI made the commitment to host such a conference periodically in order to provide a forum to share the latest information and to set new goals and priorities. This year, we have broadened the scope of the agenda to include issues on nutrition. I want to thank all of our co-sponsors and members of the Planning Committee for preparing such a comprehensive and timely program. Some of the issues and challenges facing Asia that will be addressed at this meeting are:
- in review). And since the UNGC in 2010 introduced the differentiation framework to their reporting standard, a significant number of Scandinavian corporations has chosen to report on an Advanced Level and self-assess their Sustainability Performance. Hence, in times where international opinion makers like...... Performance? And how the current assessment of Sustainability Performance by Best Practice in the UN Global Compact challenge the legitimacy of both the corporation, the UNGC and governments attempting to facilitate sustainability and CSR engagement? Best Practice is a concept frequently used by authorities...... element in assessing Sustainability Performance with the criteria for Advanced Level reporting in the UNGC differentiation framework. Though, previous empirical research by Kjaergaard (submitted, in review) has demonstrated that although the introduction of this framework generally should be acknowledged...
Lee, Joonkoo; Gereffi, Gary; Beauvais, Janet
The rise of private food standards has brought forth an ongoing debate about whether they work as a barrier for smallholders and hinder poverty reduction in developing countries. This paper uses a global value chain approach to explain the relationship between value chain structure and agrifood safety and quality standards and to discuss the challenges and possibilities this entails for the upgrading of smallholders. It maps four potential value chain scenarios depending on the degree of concentration in the markets for agrifood supply (farmers and manufacturers) and demand (supermarkets and other food retailers) and discusses the impact of lead firms and key intermediaries on smallholders in different chain situations. Each scenario is illustrated with case examples. Theoretical and policy issues are discussed, along with proposals for future research in terms of industry structure, private governance, and sustainable value chains.
Full Text Available Higher education institutions in Japan are facing unprecedented challenges today due to the following three factors:the decrease in the size of college age cohorts in the coming years; heightened expectations in the modes of instructional delivery through the advances of information and communication technologies (ICT; global competition for college students worldwide especially from English-speaking countries. This paper examines internationalization of higher education in Japan in terms of:foreign faculty members in Japan, foreign tertiary students in Japan, Japanese students studying abroad, branch campuses of foreign colleges and universities in Japan, off-shore campuses of Japanese colleges and universities, and cross-border higher education through e-learning.
Full Text Available International monitoring of drinking water and sanitation shapes awareness of countries’ needs and informs policy, implementation and research efforts to extend and improve services. The Millennium Development Goals established global targets for drinking water and sanitation access; progress towards these targets, facilitated by international monitoring, has contributed to reducing the global disease burden and increasing quality of life. The experiences of the MDG period generated important lessons about the strengths and limitations of current approaches to defining and monitoring access to drinking water and sanitation. The methods by which the Joint Monitoring Programme (JMP of WHO and UNICEF tracks access and progress are based on analysis of data from household surveys and linear regression modelling of these results over time. These methods provide nationally representative and internationally comparable insights into the drinking water and sanitation facilities used by populations worldwide, but also have substantial limitations: current methods do not address water quality, equity of access, or extra-household services. Improved statistical methods are needed to better model temporal trends. This article describes and critically reviews JMP methods in detail for the first time. It also explores the impact of, and future directions for, international monitoring of drinking water and sanitation.
Full Text Available The intention of this paper is to examine the evolution of what has become a near global and conventional school curriculum, the forces behind its development and the purposes of education, its sponsors and controllers espouse, and to set it against the massive and urgent challenges of the 21st century. This century looks to be a unique one in that it could be the tipping point between human and environmental survival, and disaster on a massive scale. The argument is that this near global view of the purpose of education is misconceived and dangerous unless there is rapid and fundamental change in the purposes of educating the young. Those older than 10 are mostly already 'lost'. In search of a more appropriate purpose and structure of curriculum, the work of a prominent few who are not yet 'lost' is drawn upon, especially that of George Martin. founder of the Oxford Martin School. The purpose of education must now, and urgently, be the survival of the human species and the planet, not only in basic terms but also in terms of controlling increasingly powerful and sophisticated computer technologies known as the Singularity that could spiral out of control.
Isiaka Abiodun Adams
Full Text Available Western dietary regulations are not in conformity with Islamic prescriptions for eatable meat (ḥalāl meat. This has led to the mushrooming of privately-driven ḥalāl regimes in many countries. This paper examines the increasing interest in ḥalāl food, analyses the factors behind this surge, its complexities, dynamics, progress and challenges. It investigates the interrelatedness of globalization, religious identity and multiculturalism in the context of ḥalāl, and the growing expression of Islamic cultural identity in a globalized world. A survey and analysis of thirty-six ḥalāl certification agencies in 18 countries, where foods are exported to Muslim countries, show that ḥalāl certification is largely championed by private and non-governmental bodies that seek to entrench Islamic food codes in the national laws. The paper identifies some countries that have institutionalized ḥalāl certification regimes for all food imports and exports.
Malheiro, Benedita; Silva, Manuel; Ribeiro, Maria Cristina; Guedes, Pedro; Ferreira, Paulo
Current engineering education challenges require approaches that promote scientific, technical, design and complementary skills while fostering autonomy, innovation and responsibility. The European Project Semester (EPS) at Instituto Superior de Engenharia do Porto (ISEP) (EPS@ISEP) is a one semester project-based learning programme (30 European Credit Transfer Units (ECTU)) for engineering students from diverse scientific backgrounds and nationalities that intends to address these goals. The students, organised in multidisciplinary and multicultural teams, are challenged to solve real multidisciplinary problems during one semester. The EPS package, although on project development (20 ECTU), includes a series of complementary seminars aimed at fostering soft, project-related and engineering transversal skills (10 ECTU). Hence, the students enrolled in this programme improve their transversal skills and learn, together and with the team of supervisors, subjects distinct from their core training. This paper presents the structure, implementation and results of the EPS@ISEP that was created in 2011 to apply the best engineering practices and promote internationalisation and engineering education innovation at ISEP.
Li, Qing; Babor, Thomas F.; Zeigler, Donald; Xuan, Ziming; Morisky, Donald; Hovell, Melbourne F.; Nelson, Toben F.; Shen, Weixing; Li, Bing
Aims Steady increases in alcohol consumption and related problems are likely to accompany China's rapid epidemiologic transition and profit-based marketing activities. We reviewed research on health promotion interventions and policies to address excessive drinking and to guide health-care reform. Methods We searched in Chinese and English language databases and included 21 studies in China published between 1980 and 2013 that covered each policy area from the WHO Global Strategy to Reduce the Harmful Use of Alcohol. We evaluated and compared preventive interventions to the global alcohol literature for cross-national applicability. Results In contrast with hundreds of studies in the global literature, 11 of 12 studies from mainland China were published in Chinese; six of ten in English were on taxation from Taiwan or Hong Kong. Most studies demonstrated effectiveness in reducing excessive drinking, and some reported the reduction of health problems. Seven were randomized controlled trials. Studies targeted schools, drink-driving, workplaces, the health sector, and taxation. Conclusions China is the world's largest alcohol market, yet there has been little growth in alcohol policy research related to health promotion interventions over the past decade. Guided by a public health approach, the WHO Global Strategy, and health reform experience in Russia, Australia, Mexico, and the USA, China could improve its public health response through better coordination and implementation of surveillance and evidence-based research, and through programmatic and legal responses such as public health law research, screening and early intervention within health systems, and the implementation of effective alcohol control strategies. PMID:25533866
This publication relates to environmental challenges of the energy sector and options for future action. Following themes are discussed: Globalisation of the energy sector; environmental challenges; the challenge of climate change; options for future action
Raquel Sosa Elízaga
Full Text Available The global sociology currently faces one of its greatest challenges: to contribute to the debate about the most serious problem which all societies have faced in recent years. The rising inequality has led to many initiatives for reflection, discussion and evaluation of public policies in order to combat poverty. Particularly, the fact that the Millennium Goals are supposed to accomplish their significance by 2015 provides the International Sociological Association (ISA the unique opportunity to contribute to those goals through their own analyses and proposals. Over many years, the ISA has promoted the integrated debate of its members on issues related to inequalities: from different perspectives such as education, health, social movements, public policies, gender problems and violence, among others. The overlapping and accumulation of inequalities has been, so to speak, the natural environment from which the ISA can take part in this international debate. This article identifies the work lines approved in the Association Program Committee Meeting held in Mexico in 2011, in the process of theAssociation’s Congress in Yokohama in 2014.
Huesemann, Michael H.
large amounts of carbon-free power. However, biomass and hydroelectric energy can only be marginally expanded and large-scale solar energy installations (i.e., wind, photovoltaics, and direct thermal) are likely to have significant negative environmental impacts. Expansion of nuclear energy is highly unlikely due to concerns over reactor safety, radioactive waste management, weapons proliferation, and cost. In view of the serious limitations and liabilities of many proposed CO2 mitigation approaches it appears that there remain only few no-regrets options such as drastic energy efficiency improvements, extensive terrestrial carbon sequestration, and cautious expansion of renewable energy generation. These promising CO2 mitigation technologies have the potential to bring about the required 20-fold reduction in per capita carbon emission only if population and economic growth are halted without delay. Thus, addressing the problem of global warming requires not only technological research and development but also a reexamination of core values that mistakenly equate material consumption and economic growth to happiness and well-being.
Barreto-Munoz, A.; Didan, K.
Continuous acquisition of global satellite imagery over the years has contributed to the creation of a long data record from AVHRR, MODIS, TM, SPOT VGT, and other sensors. These records account now for 30+ years, and as the archive grows, it becomes an invaluable source of data for many environmental related studies dealing with trends and changes from local to global scale. Synoptic global remote sensing provides a multitude of land surface state variables and serves as a major foundation for global change research. However, these records are inhibited with problems that need to be accounted for in order to understand the limits and improve the science results derived from these records. The presence of clouds, aerosols, spatial gaps, variable viewing geometry, inconsistent atmosphere corrections, multiple reprocessing, and different sensors characteristics, makes it difficult to obtain frequently high quality data everywhere and every time. Moreover, these issues are location and season dependent making it even more difficult to construct the consistent time series required to study change over time. To evaluate these records, we analyzed 30+ years (1981 to 1999 and 2000 to 2009) of daily global land surface measurements (CMG resolution) from AVHRR (N07, N09, N11 and N14) and MODIS (AQUA and TERRA, Collection 5, C5). We stratified the data based on land cover, latitudinal zone, and season and we examined the daily data quality, including cloud persistence, aerosol loads, data gaps, and an index of reliability that measures how likely an observation is acceptable for research. The aim was to generate aggregate maps of cloud distribution, aerosol levels distribution, and data reliability distribution in both time and space. This information was then converted into an uncertainty measure at the pixel level that indicates how suspect or significant a result could potentially be, depending on its location and season and consequently what geographic locations and times
Mathias, Melissa Cristina Pinto Pires
This study aims to investigate the real possibilities for the natural gas industry to become a global energy industry. So, it is necessary to define what global energy industry really means. In order to do a comparative analysis between the oil and natural gas industries, it is necessary to define three distinct stages of the evolution of an energy industry, namely internationalization, mundialization and globalization. This study analyzes the evolution of the oil industry trying to identify the main aspects that promoted changes and transformed the oil business into a global industry. Then, the evolution of the natural gas industry is analyzed, looking for similarities between the structural changes in both industries, and trying to determine what is the current stage of the natural gas industry. Despite the increase in the natural gas international trade and the prospects of growth of natural gas demand, there are still some challenges for this industry to effectively become global. Some of the challenges are the need of investments in production infrastructure, transportation and distribution sectors, the access to the main reserves, the uncertainty related to the demand evolution and the possible creation of a natural gas producers cartel, like the Organization of the Petroleum Exporting Countries (OPEC). (author)
Pin, Stephanie; Spini, Dario
Very old adults are one of the fastest-growing age groups worldwide. Yet they rarely constitute a targeted group for public policies. Drawing on the results of the centenarian studies presented in this special issue, we highlight major challenges that arise from the increase of this population. We outline several promising approaches for policy makers and professionals to develop evidence-based policies and programs that are tailored to the needs of very old adults and their families. We focus our discussion on three key topics essential to life care: the importance of integrated care to meet the complex care needs of the very old; the balance between formal and informal care; and the development of suitable places for living. Besides more specific measures, we propose that policies promoting the social integration of very old adults in their communities would be particularly helpful, as these may benefit not only the very old and their families but also individuals of all ages. We conclude that the development of suitable policies addressing the needs of the very old will benefit from future investigation of cross-cultural similarities and differences in centenarians' characteristics, available services, as well as life conditions they encounter in communities and institutional contexts.
Swartz, Leslie; Kilian, Sanja; Twesigye, Justus; Attah, Dzifa; Chiliza, Bonginkosi
Language is at the heart of mental health care. Many high-income countries have sophisticated interpreter services, but in low- and middle-income countries there are not sufficient professional services, let alone interpreter services, and task shifting is used. In this article, we discuss this neglected issue in the context of low- and middle-income countries, where task shifting has been suggested as a solution to the problem of scarce mental health resources. The large diversity of languages in low- and middle-income countries, exacerbated by wide-scale migration, has implications for the scale-up of services. We suggest that it would be useful for those who are working innovatively to develop locally delivered mental health programmes in low- and middle-income countries to explore and report on issues of language and how these have been addressed. We need to know more about local challenges, but also about local solutions which seem to work, and for this we need more information from the field than is currently available.
Klaysom, Chalida; Cath, Tazhi Y; Depuydt, Tom; Vankelecom, Ivo F J
Osmotically driven membrane processes (ODMP) have gained renewed interest in recent years and they might become a potential solution for the world's most challenging problems of water and energy scarcity. Though the concept of utilizing osmotic pressure difference between high and low salinity streams across semipermeable membranes has been explored for several decades, lack of optimal membranes and draw solutions hindered competition between forward osmosis (FO) and pressure retarded osmosis (PRO) with existing water purification and power generation technologies, respectively. Driven by growing global water scarcity and by energy cost and negative environmental impacts, novel membranes and draw solutions are being developed for ODMPs, mass and heat transfer in osmotic process are becoming better understood, and new applications of ODMPs are emerging. Therefore, OMDPs might become promising green technologies to provide clean water and clean energy from abundantly available renewable resources. This review focuses primarily on new insights into osmotic membrane transport mechanisms and on novel membranes and draw solutions that are currently being developed. Furthermore, the effects of operating conditions on the overall performance of osmotic membranes will be highlighted and future perspectives will be presented.
Famiglietti, J. S.
Climate models and decades of satellite data are converging on the unfortunate reality that Earth's water cycle is changing. Paleoclimate indicators remind us that this has always been the case. Freshwater is constantly being exchanged among the atmosphere, ocean, land and ice reservoirs, while on land, patterns of precipitation, evapotranspiration, flooding and drought are shifting. The evolving water cycle of the 21st century will likely be stronger, more variable, and will result in broad swaths of mid-latitude drying, accelerated by the depletion of the world's major groundwater aquifers. A well-defined geography of freshwater 'haves' and 'have-nots' is clearly emerging. What does water sustainability mean under such dynamic climate and hydrologic conditions, in particular when coupled with future projections of population growth? How will water managers cope with these new normals, and how will food and energy production be impacted? The responsibility of communicating this changing global water landscape falls squarely on the shoulders of the academic-research community, yet the challenge of doing so is daunting. In this Special Lecture I will review what our latest research tells us, and I will share my personal experiences with science communication and water diplomacy.
Suzuki, Y. (Japan Automobile Manufactures Association Inc., Tokyo (Japan))
This paper summarizes the global warming problem challenged by the Japan Automobile Manufacturers Association. An investigative analysis was carried out on CO2 related data. Its gists are described as follows: The rate of contribution to CO2 emission in the automotive sector is about 17%; fuel consumption improvement has long been discussed, but is in a trend of hitting the ceiling because of the needs of mounting gears for safety improvement and of vehicle upsizing; amount of fuels used is increasing year after year; the rate of the increase correlates with the economy growth; the growth of CO2 emission from automobiles would be smaller than the values given in several reports as a result of the Japanese economic growth lower than the anticipation; effects of the fuel consumption improvement are assumed to reduce CO2 emission by several percentage points in 2000; electric vehicles could reduce CO2 emission by 40% per car if nuclear power generation is partly used; fluorocarbon used in the automobile industry is for foaming, rinsing and air conditioners, with its use in the former two applications being planned to be totally abolished; and the problem thereof exists in air conditioners, for which recovery, leakage measures, and conversion to new coolants are being discussed. 12 refs., 9 figs., 1 tab.
Loftus, Patrick D; Elder, Craig T; D'Ambrosio, Troy; Langell, John T
Graduate medical education has traditionally focused on training future physicians to be outstanding clinicians with basic and clinical science research skills. This focus has resulted in substantial knowledge gains, but a modest return on investment based on direct improvements in clinical care. In today's shifting healthcare landscape, a number of important challenges must be overcome to not only improve the delivery of healthcare, but to prepare future physicians to think outside the box, focus on and create healthcare innovations, and navigate the complex legal, business and regulatory hurdles of bringing innovation to the bedside. We created an interdisciplinary and experiential medical technology design competition to address these challenges and train medical students interested in moving new and innovative clinical solutions to the forefront of medicine. Medical students were partnered with business, law, design and engineering students to form interdisciplinary teams focused on developing solutions to unmet clinical needs. Over the course of six months teams were provided access to clinical and industry mentors, $500 prototyping funds, development facilities, and non-mandatory didactic lectures in ideation, design, intellectual property, FDA regulatory requirements, prototyping, market analysis, business plan development and capital acquisition. After four years of implementation, the program has supported 396 participants, seen the development of 91 novel medical devices, and launched the formation of 24 new companies. From our perspective, medical education programs that develop innovation training programs and shift incentives from purely traditional basic and clinical science research to also include high-risk innovation will see increased student engagement in improving healthcare delivery and an increase in the quality and quantity of innovative solutions to medical problems being brought to market.
Fu Mengzi; Liu Bo
@@ Great expectations rest upon the U.S. and China, as the biggest economies in the developed and developing worlds, with regard to tackling challenges in the global economy and building a new world order. The governments have enjoyed a solid cooperation within the framework of G20.
In this paper I outline the challenges for feminist language planning in the context of a global lingua franca--English. Drawing upon the views of speakers of "World Englishes" I discuss their reactions as well as reported practices in relation to gender-inclusive language use. This reveals the complexities of managing the tension between the…
Global policy attention to tobacco control has increased significantly since the 1990 s and culminated in the first international treaty negotiated under the auspices of the World Health Organization--the Framework Convention on Tobacco Control (FCTC). Although the political process that led to the creation of the FCTC has been extensively researched, the FCTC's progression from an aspirational treaty towards a global health governance framework with tangible policy effects within FCTC member countries has not been well-understood to date. This article analyses the role of the global health network of tobacco control advocates and scientists, which formed during the FCTC negotiations during the late 1990 s, in translating countries' commitment to the FCTC into domestic policy change. By comparing the network's influence around two central tobacco control interventions (smoke-free environments and taxation), the study identifies several scope conditions, which have shaped the network's effectiveness around the FCTC's implementation: the complexity of the policy issue and the relative importance of non-health expertise, the required scope of domestic political buy-in, the role of the general public as network allies, and the strength of policy opposition. These political factors had a greater influence on the network's success than the evidence base for the effectiveness of tobacco control interventions. The network's variable success points to a trade-off faced by global health networks between their need to maintain internal cohesion and their ability to form alliances with actors in their social environment.
Khodri, Myriam; Zanchettin, Davide; Timmreck, Claudia
climate models had been subject to a common experimental protocol for the 1815 Tambora eruption in order to assess the uncertainties in the derived volcanic forcing. Results indicate substantial differences among model regarding key aerosols optical properties for the Tambora eruption. In this contribution we will discuss current uncertainties regarding relevant microphysical processes possibly underlining these large differences and challenges for current global stratospheric aerosol models to derive consensual forcing for large tropical volcanic eruptions.
Chapman, Kathryn; Adjei, Akosua; Baldrick, Paul; da Silva, Antonio; De Smet, Karen; DiCicco, Richard; Hong, Seung Suh; Jones, David; Leach, Michael W; McBlane, James; Ragan, Ian; Reddy, Praveen; Stewart, Donald I H; Suitters, Amanda; Sims, Jennifer
Biosimilars are biological medicinal products that contain a version of the active substance of an already authorised original biological medicinal product (the innovator or reference product). The first approved biosimilar medicines were small proteins, and more recently biosimilar versions of innovator monoclonal antibody (mAb) drugs have entered development as patents on these more complex proteins expire. In September 2013, the first biosimilar mAb, infliximab, was authorised in Europe. In March 2015, the first biosimilar (Zarxio™, filgrastim-sndz, Sandoz) was approved by the US Food and Drug Administration; however, to date no mAb biosimilars have been approved in the US. There are currently major differences between how biosimilars are regulated in different parts of the world, leading to substantial variability in the amount of in vivo nonclinical toxicity testing required to support clinical development and marketing of biosimilars. There are approximately 30 national and international guidelines on biosimilar development and this number is growing. The European Union's guidance describes an approach that enables biosimilars to enter clinical trials based on robust in vitro data alone; in contrast, the World Health Organization's guidance is interpreted globally to mean in vivo toxicity studies are mandatory. We reviewed our own experience working in the global regulatory environment, surveyed current practice, determined drivers for nonclinical in vivo studies with biosimilar mAbs and shared data on practice and study design for 25 marketed and as yet unmarketed biosimilar mAbs that have been in development in the past 5y. These data showed a variety of nonclinical in vivo approaches, and also demonstrated the practical challenges faced in obtaining regulatory approval for clinical trials based on in vitro data alone. The majority of reasons for carrying out nonclinical in vivo studies were not based on scientific rationale, and therefore the authors
The classification of who benefits or loses from globalization is no longer based on the sector in which one works or the skill group a person belongs to. An increasing number of workers are experiencing global competition for their jobs as there is a global convergence in the international division
Dilling, L.; Moser, S. C.
Climate change can sometimes be characterized as a "creeping environmental problem"--it is complex and long-term, involves long system lags, lacks the immediacy of everyday experience and thus is hard to perceive, and feels overwhelming to most individuals. Climate change thus does not typically attain the status of an urgent concern, taking priority over other matters for individuals, organizations or in the policy arena. We review the major reasons behind this lack of urgency, and document the observed consequences of previous communication strategies, including lack of public understanding, indifference, confusion, fear and uncertainty. We find that certain emotional motivators such as fear and guilt, while oft-employed, do not actually result in improved recognition of the urgency of the issue, nor do they typically result in action. Rather, positive and engaging approaches may be more likely to achieve this goal. We propose seven strategies to improve the communication of climate change and its urgency: 1) Abide by basic communication rules and heed the warnings of communication experts; 2) Address the emotional and the temporal components of "urgency"; 3) Increase the persuasiveness of the message; 4) Use trusted messengers-broaden the circle; 5) Use opportunities well; 6) Tap into individual and cultural strengths and values; and 7) Unite and Conquer. The multi-faceted nature of the proposed strategies reflects the unique challenges of the climate change issue as well as the need to engage all levels and sectors of societies in the solution, from individuals, to businesses, to governments. These strategies and results emerged from a multi-disciplinary, academic/practitioner workshop on the topic held at NCAR in summer 2004.
Williams, Stephanie; Fitzner, Julia; Merianos, Angela; Mounts, Anthony
During the 2009 A(H1N1) influenza pandemic, the World Health Organization (WHO) asked all Member States to provide case-based data on at least the first 100 laboratory-confirmed influenza cases to generate an early understanding of the pandemic and provide appropriate guidance to affected countries. In reviewing the pandemic surveillance strategy, we evaluated the utility of case-based data collection and the challenges in interpreting these data at the global level. To do this, we assessed compliance with the surveillance recommendation and data completeness of submitted case records and described the epidemiological characteristics of up to the first 110 reported cases from each country, aggregated into regions. From April 2009 to August 2011, WHO received over 18 000 case records from 84 countries. Data reached WHO at different time intervals, in different formats and without information on collection methods. Just over half of the 18 000 records gave the date of symptom onset, which made it difficult to assess whether the cases were among the earliest to be confirmed. Descriptive epidemiological analyses were limited to summarizing age, sex and hospitalization ratios. Centralized analysis of case-based data had little value in describing key features of the pandemic. Results were difficult to interpret and would have been misleading if viewed in isolation. A better approach would be to identify critical questions, standardize data elements and methods of investigation, and create efficient channels for communication between countries and the international public health community. Regular exchange of routine surveillance data will help to consolidate these essential channels of communication.
Full Text Available Knowledge of abundance, trends and distribution of cetacean populations is needed to inform marine conservation efforts, ecosystem models and spatial planning. We compiled a geo-spatial database of published data on cetacean abundance from dedicated visual line-transect surveys and encoded >1100 abundance estimates for 47 species from 430 surveys conducted worldwide from 1975-2005. Our subsequent analyses revealed large spatial, temporal and taxonomic variability and gaps in survey coverage. With the exception of Antarctic waters, survey coverage was biased toward the northern hemisphere, especially US and northern European waters. Overall, <25% of the world's ocean surface was surveyed and only 6% had been covered frequently enough (≥ 5 times to allow trend estimation. Almost half the global survey effort, defined as total area (km(2 covered by all survey study areas across time, was concentrated in the Eastern Tropical Pacific (ETP. Neither the number of surveys conducted nor the survey effort had increased in recent years. Across species, an average of 10% of a species' predicted range had been covered by at least one survey, but there was considerable variation among species. With the exception of three delphinid species, <1% of all species' ranges had been covered frequently enough for trend analysis. Sperm whales emerged from our analyses as a relatively data-rich species. This is a notoriously difficult species to survey visually, and we use this as an example to illustrate the challenges of using available data from line-transect surveys for the detection of trends or for spatial planning. We propose field and analytical methods to fill in data gaps to improve cetacean conservation efforts.
Full Text Available Over the past few years, Northern Norway has been perceived as a land of opportunity. Announcements of offshore oil and gas discoveries off the coast of Finnmark have contributed to increased market activity in related sectors like service and construction. However, regional firms continue to score at the bottom of innovation indexes and seldom compete on international markets. Based on in-depth interviews with representatives from key businesses in three sectors in Northern Norway, we examine the bottlenecks that have prevented these firms from gaining new market positions through the interplay of these regional firms and agencies with the Global Production Network (GPN. We adopt the concept of “strategic coupling” and explore whether an actor approach can contribute to an improved understanding of this relationship. The paper demonstrates that regional strategies and public policy differ between the sectors. Public policy is important for regional firms within the petroleum sector. However, the funds available for regional firms continue to be limited due to the size and relevance of the measures. In the construction sector, public policy instruments are important, but not sufficiently adapted to the challenges these firms face. While the petroleum sector receives support and backing from regional agencies in order to connect to GPN, the wind power sector is actively hindered by the same agencies. The former have the opportunity to take part in new regional path creation; the latter have experienced a lack of strategic cooperation and face the risk of reducing strategic couplings to GPN, leading to path dependent processes that lock these firms into traditional and low-tech sectors.
David M.P. Jacoby
Full Text Available With broad distributions, diadromous fishes can be exposed to multiple threats at different stages of development. For the primarily catadromous eels of the family Anguillidae, there is growing international concern for the population abundance and escapement trends of some of these species and yet incomplete knowledge of their remarkable life-histories hampers management and conservation. Anguillids experience a suite of pressures that include habitat loss/modification, migration barriers, pollution, parasitism, exploitation, and fluctuating oceanic conditions that likely have synergistic and regionally variable impacts, even within species. In beginning to redress this rather fragmented picture, we evaluated the extinction risk of these species using the IUCN Red List of Threatened Species Categories and Criteria to infer population-wide trends from catch and monitoring data. Here we consolidate and build upon these species assessments by presenting an overview of the current state of global eel data and conservation, categorising the knowledge gaps and geographic regions where resources are needed and discussing future recommendations to improve our understanding of anguillids. We find stark disparity between the quality and length of data available to assess population trends and conservation priorities in temperate and tropical anguillids. Of the 13 species assessed, four were listed as ‘Threatened’ (Vulnerable, Endangered or Critically Endangered; four were Near Threatened, three were Data Deficient and two were deemed Least Concern. Comparing with other diadromous species, we examine the multiple threats that impact eels during their different life-history stages, highlighting the challenges of applying the Red List Categories and Criteria to geographically-expansive, catadromous and panmictic groups of species.
Bodegom, P. V.
In recent years a number of approaches have been developed to provide alternatives to the use of plant functional types (PFTs) with constant vegetation characteristics for simulating vegetation responses to climate changes. In this presentation, an overview of those approaches and their challenges is given. Some new approaches aim at removing PFTs altogether by determining the combination of vegetation characteristics that would fit local conditions best. Others describe the variation in traits within PFTs as a function of environmental drivers, based on community assembly principles. In the first approach, after an equilibrium has been established, vegetation composition and its functional attributes can change by allowing the emergence of a new type that is more fit. In the latter case, changes in vegetation attributes in space and time as assumed to be the result intraspecific variation, genetic adaptation and species turnover, without quantifying their respective importance. Hence, it is assumed that -by whatever mechanism- the community as a whole responds without major time lags to changes in environmental drivers. Recently, we showed that intraspecific variation is highly species- and trait-specific and that none of the current hypotheses on drivers of this variation seems to hold. Also genetic adaptation varies considerably among species and it is uncertain whether it will be fast enough to cope with climate change. Species turnover within a community is especially fast in herbaceous communities, but much slower in forest communities. Hence, it seems that assumptions made may not hold for forested ecosystems, but solutions to deal with this do not yet exist. Even despite the fact that responsiveness of vegetation to environmental change may be overestimated, we showed that -upon implementation of trait-environment relationships- major changes in global vegetation distribution are projected, to similar extents as to those without such responsiveness.
World environmental policy. Conceptual approaches of German political science in response to the challenges of Global Change; Weltumweltpolitik - Global Change als Herausforderung fuer die deutsche Politikwissenschaft
Biermann, F. [Potsdam-Institut fuer Klimafolgenforschung (PIK), Potsdam (Germany); Dingwerth, K. [Freie Univ. Berlin (Germany). Fachbereich Politik- und Sozialwissenschaften
This paper describes, first, the international community of social scientists working on global change, and elaborates on possible contributions to this community by German political scientists. Second, the paper examines three new conceptual approaches to analysing global change, namely the Syndromes of Global Change approach, Earth System Analysis, and Sustainability Science. The paper then elaborates on a number of ways in which German political science could respond to the academic and political challenges posed by global change. It concludes by emphasizing the need for a new approach, focusing on 'world environmental policy analysis' that would bridge traditional (environmental) policy analysis, international relations research, and comparative politics. (orig.) [German] Der Aufsatz beschreibt die Wissenschaftslandschaft der internationalen sozialwissenschaftlichen Global-Change-Forschung mit besonderem Augenmerk auf moegliche Beitraege der deutschen Politologie. Mit den 'Syndromen des Globalen Wandels', der 'Erdsystemanalyse' und der 'Nachhaltigkeitswissenschaft' werden drei neuere konzeptionelle Innovationen vorgestellt, mit denen der Herausforderung des Globalen Wandels begegnet werden soll. Anschliessend werden Wege skizziert, wie die Politikwissenschaft auf die neuen gesellschaftlichen und wissenschaftlichen Probleme des Globalen Wandels reagieren koennte. Eine Schlussfolgerung ist ein Plaedoyer fuer die Entwicklung einer eigenstaendigen Weltumweltpolitik-Analyse an der Schnittstelle von traditioneller Policy-Analyse, Internationalen Beziehungen/Aussenpolitik sowie Komparatistik. (orig./CB)
Hadingham Jacqui; Coovadia Hoosen M
Abstract Globalisation affects all facets of human life, including health and well being. The HIV/AIDS epidemic has highlighted the global nature of human health and welfare and globalisation has given rise to a trend toward finding common solutions to global health challenges. Numerous international funds have been set up in recent times to address global health challenges such as HIV. However, despite increasingly large amounts of funding for health initiatives being made available to poore...
Magnusson, Roger S
This paper considers how we can conceptualize a "global response" to chronic, non-communicable diseases (NCDs)--including cardiovascular disease, cancer, diabetes, and tobacco-related diseases. These diseases are the leading cause of death and disability in developed countries, and also in developing countries outside sub-Saharan Africa. The paper reviews emerging and proposed initiatives for global NCD governance, explains why NCDs merit a global response, and the ways in which global initiatives ultimately benefit national health outcomes. As the global response to NCDs matures, and the number of initiatives and partnerships increases, it will become increasingly important to map their respective contributions, and to evaluate progress overall. It is not yet clear what institutional mechanism, if any, will rise above the sea of surrounding initiatives to play this global role. This paper therefore aims to provide a conceptual map for making sense of what individual initiatives contribute to global governance. This map also draws attention to the distinctively "global" public health functions that a global response to NCDs should seek to discharge.
Full Text Available Abstract The purpose of this study was to briefly illustrate some of the challenges and realities of national and international Paralympic sports. The elite disabled athlete paradigm is still not widely known in the world of regular sports competitions. The winning elite disabled athletes are restricted to a few countries, including the U.S., Canada, Germany, China, and Australia, with limited distribution of disability sport opportunities in other countries. This tendency for the success of a minority of countries reflects global problems of social vulnerability in accessibility (e.g., in dismantling the stigma of disability, political vulnerability (e.g., representative organizations of sports for the disabled do not fully pratice the philosophy of "sport for all", and economic vulnerability (e.g., lack of opportunities for training, assistive sports technology, and sponsorships. Furthermore, elite Paralympic athletes have become veterans. For example, the participation of Brazilian elite athletes in the 1984 Paralympics marked the beginning of a new generation of athletes (approximately 16% who returned to the Games in 1988. In both 2008 and 2012, nearly 28% of total participants were Brazilian veterans. Although this picture reveals longevity of athletes in the sport, there are many limitations in sports accessibility, often due to geographical centralization of opportunities in large urban centers. Yet, today, the world of Paralympic sport has been transformed into a sports spectacle, thanks to the exceptional performance of some athletes, to the technology of mass communication, and to the support of audiences during the Games. These sport "superstars" offer the world new images and new constructs of "ability." While this forum has helped to bring attention to these "heroes," other Brazilian athletes (and from other countries as well are still waiting for their opportunities. Indeed, worldwide, young blind individuals, those in wheelchairs
Arafat, Humayun [Department of Computer Science and Engineering, The Ohio State University, Columbus OH USA; Dinan, James [Mathematics and Computer Science Division, Argonne National Laboratory, Lemont IL USA; Krishnamoorthy, Sriram [Computer Science and Mathematics Division, Pacific Northwest National Laboratory, Richland WA USA; Balaji, Pavan [Mathematics and Computer Science Division, Argonne National Laboratory, Lemont IL USA; Sadayappan, P. [Department of Computer Science and Engineering, The Ohio State University, Columbus OH USA
Task parallelism is an attractive approach to automatically load balance the computation in a parallel system and adapt to dynamism exhibited by parallel systems. Exploiting task parallelism through work stealing has been extensively studied in shared and distributed-memory contexts. In this paper, we study the design of a system that uses work stealing for dynamic load balancing of task-parallel programs executed on hybrid distributed-memory CPU-graphics processing unit (GPU) systems in a global-address space framework. We take into account the unique nature of the accelerator model employed by GPUs, the significant performance difference between GPU and CPU execution as a function of problem size, and the distinct CPU and GPU memory domains. We consider various alternatives in designing a distributed work stealing algorithm for CPU-GPU systems, while taking into account the impact of task distribution and data movement overheads. These strategies are evaluated using microbenchmarks that capture various execution configurations as well as the state-of-the-art CCSD(T) application module from the computational chemistry domain.
Thais Maria Machado Lemos Ribeiro; Cristina Y A Inoue
Solid waste has been growing at an exponential rate because of unsustainable production and consumption patterns. For that reason, it is considered a global issue both in the international political economy perspective and in local and global governance, with multiple actors and levels of analysis, highlighting waste pickers as relevant actors.
Cameron, Roslyn; O'Hanlon-Rose, Terry
The complex interplay of technological advances, global demographic trends and macroeconomic forces has seen the emergence of global markets, economies, supply chains and labour markets. The use of skilled migration policy and initiatives for many countries feeling the effects of aging populations and skill shortages adds another dimension to this…
Full Text Available The article complexly investigates the processes of emigration from Lithuania and other European Union countries in Central and Eastern Europe which appear under contemporary conditions of economic globalization. The main attention is given to those determinants of emigration which are caused by the processes taking place in the global economy, social and economic circumstances occuring globally. The theoretical study for the processes of migration and emigration in contemporary environment of globalization has been made. The original theoretical conception intended to analyze migration flows, motives and reasons of emigration, allowing to complexly assess the impact of various economic determinants has been suggested: on the basis of this conception researches of emigration from Lithuania and other European Union countries in Central and Eastern Europe have been carried out and peculiarities of the processes of emigration reflecting the impact of circumstances determined by economic globalization have been highlighted. Carrying out empirical researches the instrumentation of economic mathematical modeling has been used.
Muhe Lulu M
.6%. Countries addressed these by piggy backing IMCI follow-up with routine supervisory visits. Conclusions Financial challenges to ICMT scale-up and follow-up after training are common. As IMCI is accepted globally as one of the key strategies to meet MDG4 several steps need to be taken to facilitate rapid acceleration of ICMT, including reviewing core competencies followed by competency-driven shortened training duration or 'on the job' training, 'distance learning' or training using mobile phones. Linkages with other 'better-funded' programmes e.g. HIV or malaria need to be improved. Routine Primary Health Care (PHC supervision needs to include follow-up after ICMT.
19. Colloquium lecture at College of Management , National Chiao Tung University, June 22, 2012. Title: Unified Framework in Global Supply Chain and...the well-known logistic equation in population dynamical systems can be reformulated as a global optimization problem, which could have at most 2n...making, supply chain , scheduling problems, and computational mechanics, etc. Impacts to the communities: The canonical duality theory is now
Globally, mother to child transmission (MTCT) of hepatitis B virus (HBV) is the major route of transmission, while horizontal transmission, between adults, dominates in countries such as Norway. 2 billion people worldwide have serologic evidence of past or present infection with hepatitis, emphasizing that this infectious disease should be acknowledged as a global health problem in line with HIV, tuberculosis and malaria. MTCT of hepatitis B is the most important factor for developing a pers...
Author of this review submits a comprehensive report of his long-lasting research regarding the global pollution by endocrine disruptors (EDs), EDs and diabetes and obesity, EDs and the thyroid in highly polluted Slovakia, Ah-receptor: the central pivot responsible for such global "EDs disaster", EDs and immune system, EDs and testosterone, EDs in mothers and newborns, EDs and human genome, and EDs at the beginning of the millennium.
International business world has been undergoing a period of rapid transformation. Trends towards globalization, supported with multimodal transport and supply chain facilities are all reshaping the world’s trading patterns and consequently physical trade flows. The supply chain has become one of the main globalization forces today. Transportation occupies one-third of the amount in the logistics costs and transportation systems influence the performance of supply chain management. Only a goo...
Hălăngescu, Constantin I.
Structured as an essay, this workpaper aims to present sui generis one point of view on the relationship between two models of the social-human typology in the context of globalization: homo oeconomicus and homo academicus. Being only a starting point for futher research into a tripartite structure, the paper preliminary presents views on views of MAN’s multivalent positions between vocation and the adaptation to globalization flows, the dilemmas and paradoxes between the oeconomicus and acad...
Wondwossen A Gebreyes
Full Text Available Zoonotic infectious diseases have been an important concern to humankind for more than 10,000 years. Today, approximately 75% of newly emerging infectious diseases (EIDs are zoonoses that result from various anthropogenic, genetic, ecologic, socioeconomic, and climatic factors. These interrelated driving forces make it difficult to predict and to prevent zoonotic EIDs. Although significant improvements in environmental and medical surveillance, clinical diagnostic methods, and medical practices have been achieved in the recent years, zoonotic EIDs remain a major global concern, and such threats are expanding, especially in less developed regions. The current Ebola epidemic in West Africa is an extreme stark reminder of the role animal reservoirs play in public health and reinforces the urgent need for globally operationalizing a One Health approach. The complex nature of zoonotic diseases and the limited resources in developing countries are a reminder that the need for implementation of Global One Health in low-resource settings is crucial. The Veterinary Public Health and Biotechnology (VPH-Biotec Global Consortium launched the International Congress on Pathogens at the Human-Animal Interface (ICOPHAI in order to address important challenges and needs for capacity building. The inaugural ICOPHAI (Addis Ababa, Ethiopia, 2011 and the second congress (Porto de Galinhas, Brazil, 2013 were unique opportunities to share and discuss issues related to zoonotic infectious diseases worldwide. In addition to strong scientific reports in eight thematic areas that necessitate One Health implementation, the congress identified four key capacity-building needs: (1 development of adequate science-based risk management policies, (2 skilled-personnel capacity building, (3 accredited veterinary and public health diagnostic laboratories with a shared database, and (4 improved use of existing natural resources and implementation. The aim of this review is to
Gebreyes, Wondwossen A; Dupouy-Camet, Jean; Newport, Melanie J; Oliveira, Celso J B; Schlesinger, Larry S; Saif, Yehia M; Kariuki, Samuel; Saif, Linda J; Saville, William; Wittum, Thomas; Hoet, Armando; Quessy, Sylvain; Kazwala, Rudovick; Tekola, Berhe; Shryock, Thomas; Bisesi, Michael; Patchanee, Prapas; Boonmar, Sumalee; King, Lonnie J
Zoonotic infectious diseases have been an important concern to humankind for more than 10,000 years. Today, approximately 75% of newly emerging infectious diseases (EIDs) are zoonoses that result from various anthropogenic, genetic, ecologic, socioeconomic, and climatic factors. These interrelated driving forces make it difficult to predict and to prevent zoonotic EIDs. Although significant improvements in environmental and medical surveillance, clinical diagnostic methods, and medical practices have been achieved in the recent years, zoonotic EIDs remain a major global concern, and such threats are expanding, especially in less developed regions. The current Ebola epidemic in West Africa is an extreme stark reminder of the role animal reservoirs play in public health and reinforces the urgent need for globally operationalizing a One Health approach. The complex nature of zoonotic diseases and the limited resources in developing countries are a reminder that the need for implementation of Global One Health in low-resource settings is crucial. The Veterinary Public Health and Biotechnology (VPH-Biotec) Global Consortium launched the International Congress on Pathogens at the Human-Animal Interface (ICOPHAI) in order to address important challenges and needs for capacity building. The inaugural ICOPHAI (Addis Ababa, Ethiopia, 2011) and the second congress (Porto de Galinhas, Brazil, 2013) were unique opportunities to share and discuss issues related to zoonotic infectious diseases worldwide. In addition to strong scientific reports in eight thematic areas that necessitate One Health implementation, the congress identified four key capacity-building needs: (1) development of adequate science-based risk management policies, (2) skilled-personnel capacity building, (3) accredited veterinary and public health diagnostic laboratories with a shared database, and (4) improved use of existing natural resources and implementation. The aim of this review is to highlight
Earthquake risk, like natural risks in general, has become a highly dynamic and globally interdependent phenomenon. Due to the "urban explosion" in the Third World, an increasingly complex cross linking of critical infrastructure and lifelines in the industrial nations and a growing globalisation of the world's economies, we are presently facing a dramatic increase of our society's vulnerability to earthquakes in practically all seismic regions on our globe. Such fast and global changes cannot be captured with conventional earthquake risk models anymore. The sciences in this field are, therefore, asked to come up with new solutions that are no longer exclusively aiming at the best possible quantification of the present risks but also keep an eye on their changes with time and allow to project these into the future. This does not apply to the vulnerablity component of earthquake risk alone, but also to its hazard component which has been realized to be time-dependent, too. The challenges of earthquake risk dynamics and -globalisation have recently been accepted by the Global Science Forum of the Organisation for Economic Co-operation and Development (OECD - GSF) who initiated the "Global Earthquake Model (GEM)", a public-private partnership for establishing an independent standard to calculate, monitor and communicate earthquake risk globally, raise awareness and promote mitigation.
bal Challenges in the Domestic Appliances IndustryAbstract: The domestic appliances industry is a mature industry. Changes in the business environment such as political, law, cultural, social, ecological and technological influences have an effect on the future development of this industry. Challenges to producers in this industry are oriented towards the further globalisation of the business, managing processes, new product and innovations development, and towards establishing and empowermen...
This paper mainly talks about the currently hot topic-globalization. Firstly, it brings out the general trend about globalization and how to better understand its implication. Secondly, it largely focuses on how to deal with it properly, especially for international marketers. Then, facing with the overwhelming trend, it is time for us to think about seriously what has globalization brought to us. Last but not least, it summarized the author's personal view about the future of globalization and how should we go.
Full Text Available There is no singular globalization, nor is the result of an individual agent. We could start by saying that global action has different angles and subjects who perform it are different, as well as its objectives. The global is an invisible invasion of materials and immediate effects.
Singh, Ilina; Filipe, Angela M; Bard, Imre; Bergey, Meredith; Baker, Lauren
Globalization of ADHD and the rise of cognitive enhancement have raised fresh concerns about the validity of ADHD diagnosis and the ethics of stimulant drug treatment. We review the literature on these two emerging phenomena, with a focus on the corresponding social, scientific and ethical debates over the universality of ADHD and the use of stimulant drug treatments in a global population of children and adolescents. Drawing on this literature, we reflect on the importance of ethically informed, ecologically sensitive clinical practices in relation to ADHD diagnosis and treatment.
Dramatic changes have taken place in global environment and sustainable development patterns since 1992, when the United Nations Conference on Environment and Development convened in Rio de Janeiro, Brazil. The global landscape of the environment and development has been altered by an expanding world economy, the rise of China and other emerging economies, and a smoothly developing green economy. Since 1996, when sustainable development was made a national strategy in China, amazing achievements have been accomplished in such aspects as population control, energy efficiency, emissions reduction and ecological conservation.
Wilson, Christopher B; Karp, Christopher L
Vaccines are one of the most impactful and cost-effective public health measures of the twentieth century. However, there remain great unmet needs to develop vaccines for globally burdensome infectious diseases and to allow more timely responses to emerging infectious disease threats. Recent advances in the understanding of immunological principles operative not just in model systems but in humans in concert with the development and application of powerful new tools for profiling human immune responses, in our understanding of pathogen variation and evolution, and in the elucidation of the structural aspects of antibody-pathogen interactions, have illuminated pathways by which these unmet needs might be addressed. Using these advances as foundation, we herein present a conceptual framework by which the discovery, development and iterative improvement of effective vaccines for HIV, malaria and other globally important infectious diseases might be accelerated.
Published studies have reported that Information System (IS) projects succeed or fail based on how effectively the organizational issues were understood and addressed in the specification, development and implementation stages of the project. This is particularly true in the design and delivery of Inter-Organizational Systems (IOS) that can affect…
Ng, Shun-wing; Tang, Sylvia Yee Fan
This article presents a study of how to attract students from the Asian markets to pursue higher education in Hong Kong. The study found that the strategies of internationalization, at both the system level and the institutional level, attempted to address problems generated from the barriers of exporting higher education and so build on the…
Pertoldi, Cino; Bijlsma, R.; Loeschcke, Volker
Despite recent advances in conservation genetics and related disciplines and the growing impact that conservation genetics is having in conservation biology, our knowledge on several key issues in the field is still insufficient. Here we identify some of these issues together with addressing several
This paper examines the level of cooperation which China and the EU undertake on global issues,especially with regard to the future roles of international organizations such as the UN,the IMF,the World Bank,the G20,the form and practice of multilateralism,the prospects and direction of a multipolar/core world,and whether the two tend to be partners rather than competitors on issues of climate change and energy policy.It applies the approach of international security cooperation and relies primarily on documentary evidence(e.g.,communiqués on global or regional governance aspects,issued at EU-China summits or separately by each).This paper argues that the"misunderstanding"on principles between the EU and China is at odds with the growing economic interdependencies between the two sides.The EU and China,two of the pillars in the emerging multipolar order,have fundamentally opposed attitudes to key aspects of global politics,such as sovereignty and multilateralism,and these differences are bound to create further tensions in the development of global governance regimes in the future.The originality of this paper lies in that it moves beyond the traditional form of investigating on how each China and the EU perceive each other in cooperation terms by focusing instead on the level of cooperation both partners pursue with regard to multilateralism and within the activities of international organizations.
P. Knorringa (Peter); K. Nadvi (Khalid)
markdownabstract__Abstract__ This paper explores the intersection between three processes associated with globalisation. First, the rise of emerging economies like China, Brazil and India, the so-called ‘Rising Powers’, and their potential to define the contours of globalisation, global production
Nell, Phillip Christopher
This is part of a case series. The case focuses on describing and analysing the environment, profitability and competitiveness of the global pharmaceutical industry, and to evaluate the current and future strategy of Pfizer. It features a large number of tables with quantitative data that help...... initiatives and responses to the market changes....
The two notions of "globalization" and "knowledge society" are often assumed to be relatively neutral descriptions of contemporary social and cultural developments, although they are embedded in discourses on power and domination. In this paper the argument is made that both these notions can be understood as expressions of an ideology of…
This paper revisits and revisions Education for All (EFA) in the age of global migration with the aim of developing more inclusive approaches towards social justice and equity in education. Drawing on cases of internal and international migration in China and Canada, this paper compares and contrasts policies and practices in the education of…
This special research topic eBOOK contains six review articles, three mini reviews and four original research articles. It opens up exciting perspectives on global health issues related to aflatoxins in the food chain and on the development of suitable strategies for preventing toxigenic fungal grow...
Sauls, Jeff; Gudigantala, Naveen
Managing IT security and assurance is a top priority for organizations. Aware of the costs associated with a security or privacy breach, organizations are constantly vigilant about protecting their data and IT systems. In addition, organizations are investing heavily in IT resources to keep up with the challenges of managing their IT security and…
Grimsaeth, Gerd; Hallås, Bjørg Oddrun
The lesson study (LS) model, which originated in Japan, has become popular all over the world. This article will highlight some of the challenges encountered when the LS model was picked up and introduced in a local school context in a Norwegian municipality. The article views this process in the light of research on LS-model transfer into local…
The presence of parallel structures, and even criminal groups, sponsored, or instigated, by the official Government of Serbia, have a serious impact on the situation. Those structures and groups are a constant challenge against legal institutions of Kosova, in their efforts to execute the sovereignty throughout its territory.
Rhodes, Christopher J
An overview is presented of the determined degree of global land degradation (principally occurring through soil erosion), with some consideration of its possible impact on global food security. Most determinations of the extent of land degradation (e.g. GLASOD) have been made on the basis of "expert judgement" and perceptions, as opposed to direct measurements of this multifactorial phenomenon. More recently, remote sensing measurements have been made which indicate that while some regions of the Earth are "browning" others are "greening". The latter effect is thought to be due to fertilisation of the growth of biomass by increasing levels of atmospheric CO2, and indeed the total amount of global biomass was observed to increase by 3.8% during the years 1981-2003. Nonetheless, 24% of the Earth's surface had occasioned some degree of degradation in the same time period. It appears that while long-term trends in NDVI (normalised difference vegetation index) derivatives are only broad indicators of land degradation, taken as a proxy, the NDVI/NPP (net primary productivity) trend is able to yield a benchmark that is globally consistent and to illuminate regions in which biologically significant changes are occurring. Thus, attention may be directed to where investigation and action at the ground level is required, i.e. to potential "hot spots" of land degradation and/or erosion. The severity of land degradation through soil erosion, and an according catastrophic threat to the survival of humanity may in part have been overstated, although the rising human population will impose inexorable demands for what the soil can provide. However the present system of industrialised agriculture would not be possible without plentiful provisions of cheap crude oil and natural gas to supply fuels, pesticides, herbicides and fertilisers. It is only on the basis of these inputs that it has been possible for the human population to rise above 7 billion. Hence, if the cheap oil and gas
Slepniov, Dmitrij; Jørgensen, Claus; Wæhrens, Brian Vejrum
This paper addresses the phenomenon of global operations networks and how they change over time. The paper is based on the cases of three Danish companies and their global operations networks. It finds a number of common patterns highlighting some organisational effects and managerial challenges...
近30年以来世界持续发生了很大的变化,而变化发展最大的无疑是中国.到2050年,全球人口预计从目前的60亿增加到90亿左右,食品保障将是巨大的挑战;而随着城市化进程的深入,逐步进入老龄社会,人们的生活压力也越来越大,也越来越关心自己的健康状况.到2015年,中国的GDP将达到8600亿美元,占全球的18%,保持为全球第二大经济体;而到2050年,中国GDP达到5万亿美元,便成为全球第一大经济体.不过,中国还面临更大的挑战包括:能源短缺、食品保障、人口增长和老龄化、城市化、生活方式改变以及更多的健康问题.这些大趋势应该引起食品科学家、食品工业和政府相关部门的重视,从而制定出应对这些挑战的策略.食品安全问题同样也是我们必须面对的重大挑战之一.食品和配料企业用创新思维正确应对这些重大挑战,这样我国食品工业才能随着经济的腾飞而同步发展.%In the past thirty years, our world has been changed significantly and continuously, while China changed the most.Our globe are getting warmer and are facing more energy problems, and the population will be increased from about 6 billion to 9 billion in year of 2050, while food security is still a huge challenge.Now we are entering an aging society, while urbanization is happening faster than ever.People are trying to improve their health situation as life styles are much pressured.By 2015 China' s GDP will reach 8.6 trillion USD and cover 18％ globally to become the No.2 economy.China will become the No.1 economy in 2050 with GDP of 50 trillion USD.However, China are facing even bigger challenges on energy shortage, food security, population growing and aging, urbanization, life style changing and more demands on health attention.These mega trends should get much more attention from food scientist,food industry and government officials, in order to have strategic direction against these
Rosegrant, Mark W.; Msangi, Siwa; Sulser, Timothy B.; Valmonte-Santos, Rowena
"Rising world fuel prices, the growing demand for energy, and concerns about global warming are the key factors driving the increasing interest in renewable energy sources, and in biofuels in particular. But some policymakers and analysts have voiced concern that aggressive growth in biofuel production could “crowd out” production of food crops in some developing countries, creating a tension between the need for energy and the need for food and feed. This brief investigates the interaction b...
Nouwen, Sarah M. H.; Werner, Wouter G.
This is the accepted manuscript. The final version is available from OUP at http://jicj.oxfordjournals.org/content/early/2014/12/17/jicj.mqu078.full. Over the past two decades, international criminal law has been increasingly institutionalized and has become one of the dominant frames for defining issues of justice and conflict resolution. Indeed, international criminal law is often presented as the road towards global justice. But the rise of international criminal law and its equation wi...
Elizabeth G. Hanna
Full Text Available Human thermoregulation and acclimatization are core components of the human coping mechanism for withstanding variations in environmental heat exposure. Amidst growing recognition that curtailing global warming to less than two degrees is becoming increasing improbable, human survival will require increasing reliance on these mechanisms. The projected several fold increase in extreme heat events suggests we need to recalibrate health protection policies and ratchet up adaptation efforts. Climate researchers, epidemiologists, and policy makers engaged in climate change adaptation and health protection are not commonly drawn from heat physiology backgrounds. Injecting a scholarly consideration of physiological limitations to human heat tolerance into the adaptation and policy literature allows for a broader understanding of heat health risks to support effective human adaptation and adaptation planning. This paper details the physiological and external environmental factors that determine human thermoregulation and acclimatization. We present a model to illustrate the interrelationship between elements that modulate the physiological process of thermoregulation. Limitations inherent in these processes, and the constraints imposed by differing exposure levels, and thermal comfort seeking on achieving acclimatization, are then described. Combined, these limitations will restrict the likely contribution that acclimatization can play in future human adaptation to global warming. We postulate that behavioral and technological adaptations will need to become the dominant means for human individual and societal adaptations as global warming progresses.
As water is an essential component of the planetary life support system, water deficiency constitutes an insecurity that has to be overcome in the process of socio-economic development. The paper analyses the origin and appearance of blue as well as green water scarcity on different scales and with particular focus on risks to food production and water supply for municipalities and industry. It analyses water scarcity originating from both climatic phenomena and water partitioning disturbances on different scales: crop field, country level and the global circulation system. The implications by 2050 of water scarcity in terms of potential country-level water deficits for food self-reliance are analysed, and the compensating dependence on trade in virtual water for almost half the world population is noted. Planetary-scale conditions for sustainability of the global water circulation system are discussed in terms of a recently proposed Planetary Freshwater Boundary, and the consumptive water use reserve left to be shared between water requirements for global food production, fuelwood production and carbon sequestration is discussed. Finally, the importance of a paradigm shift in the further conceptual development of water security is stressed, so that adequate attention is paid to water's fundamental role in both natural and socio-economic systems.
Hanna, Elizabeth G; Tait, Peter W
Human thermoregulation and acclimatization are core components of the human coping mechanism for withstanding variations in environmental heat exposure. Amidst growing recognition that curtailing global warming to less than two degrees is becoming increasing improbable, human survival will require increasing reliance on these mechanisms. The projected several fold increase in extreme heat events suggests we need to recalibrate health protection policies and ratchet up adaptation efforts. Climate researchers, epidemiologists, and policy makers engaged in climate change adaptation and health protection are not commonly drawn from heat physiology backgrounds. Injecting a scholarly consideration of physiological limitations to human heat tolerance into the adaptation and policy literature allows for a broader understanding of heat health risks to support effective human adaptation and adaptation planning. This paper details the physiological and external environmental factors that determine human thermoregulation and acclimatization. We present a model to illustrate the interrelationship between elements that modulate the physiological process of thermoregulation. Limitations inherent in these processes, and the constraints imposed by differing exposure levels, and thermal comfort seeking on achieving acclimatization, are then described. Combined, these limitations will restrict the likely contribution that acclimatization can play in future human adaptation to global warming. We postulate that behavioral and technological adaptations will need to become the dominant means for human individual and societal adaptations as global warming progresses.
Stranieri, Andrew; Vaughan, Stephen
As globalisation advances, patients in many nations increasingly access diverse medical systems including Western medicine, Traditional Chinese Medicine, Homeopathy and Ayervedic medicine. The trend toward co-existence of medical systems presents challenges for health informatics including the need to develop standards that can encompass the diversity required, the need to develop software applications that effectively inter-operate across diverse systems and the need to support patients when evaluating competing systems. This article advances the notion that the challenges can most effectively be met with the development of informatics approaches that do not assume the superiority of one medical system over another. Argument visualization to support patient decision making in selecting an appropriate medical system is presented as an application that exemplifies this stance.
Icarbord Tshabangu; Allen Msafiri
The study explored notions of quality in education and the challenges facing Tanzania. The inquiry adopted a humanist approach to determining levels of quality in schools, thus respondents recorded their perceptions on key issues on quality education, relevant to Tanzania. The study used mixed methods and non-probability sampling which selected 20 schools involving 200 participants. Data was collected using written accounts and qualitative questionnaires and a preliminary quantitative questio...
Tucker, Geoffrey; DeSilva, Binodh; Dressman, Jennifer; Ito, Michiho; Kumamoto, Takuya; Mager, Don; Mahler, Hanns-Christian; Maitland-van der Zee, Anke H; Pauletti, Giovanni M; Sasaki, Hitoshi; Shah, Vinod; Tang, Daniel; Ward, Michael
The chairs of each of the 8 Special Interest Groups of the Board of Pharmaceutical Sciences of the International Pharmaceutical Federation have compiled opinions with regard to major challenges for the pharmaceutical sciences over the next 5-10 years. Areas covered are drug design and discovery, natural products, formulation design and pharmaceutical technology, pharmacokinetics/pharmacodynamics and systems pharmacology, translational and personalized medicine, biotechnology, analytical sciences and quality control, and regulatory science.
Ilukor, John; Birner, Regina; Nielsen, Thea
Providing adequate animal health services to smallholder farmers in developing countries has remained a challenge, in spite of various reform efforts during the past decades. The focuses of the past reforms were on market failures to decide what the public sector, the private sector, and the "third sector" (the community-based sector) should do with regard to providing animal health services. However, such frameworks have paid limited attention to the governance challenges inherent in the provision of animal health services. This paper presents a framework for analyzing institutional arrangements for providing animal health services that focus not only on market failures, but also on governance challenges, such as elite capture, and absenteeism of staff. As an analytical basis, Williamson's discriminating alignment hypothesis is applied to assess the cost-effectiveness of different institutional arrangements for animal health services in view of both market failures and governance challenges. This framework is used to generate testable hypotheses on the appropriateness of different institutional arrangements for providing animal health services, depending on context-specific circumstances. Data from Uganda and Kenya on clinical veterinary services is used to provide an empirical test of these hypotheses and to demonstrate application of Williamson's transaction cost theory to veterinary service delivery. The paper concludes that strong public sector involvement, especially in building and strengthening a synergistic relation-based referral arrangement between paraprofessionals and veterinarians is imperative in improving animal health service delivery in developing countries.
Truxal, John G.
Cited are the educational challenges of undergraduate, graduate, and professional engineering programs; the main emphasis is on the challente to provide engineering education for non-engineering students at both the undergraduate and adult levels. The need for such a program stems from a conviction that no citizen can be considered educated in…
Lewis, Jedediah K; Bischof, John C; Braslavsky, Ido; Brockbank, Kelvin G M; Fahy, Gregory M; Fuller, Barry J; Rabin, Yoed; Tocchio, Alessandro; Woods, Erik J; Wowk, Brian G; Acker, Jason P; Giwa, Sebastian
The first Organ Banking Summit was convened from Feb. 27 - March 1, 2015 in Palo Alto, CA, with events at Stanford University, NASA Research Park, and Lawrence Berkeley National Labs. Experts at the summit outlined the potential public health impact of organ banking, discussed the major remaining scientific challenges that need to be overcome in order to bank organs, and identified key opportunities to accelerate progress toward this goal. Many areas of public health could be revolutionized by the banking of organs and other complex tissues, including transplantation, oncofertility, tissue engineering, trauma medicine and emergency preparedness, basic biomedical research and drug discovery - and even space travel. Key remaining scientific sub-challenges were discussed including ice nucleation and growth, cryoprotectant and osmotic toxicities, chilling injury, thermo-mechanical stress, the need for rapid and uniform rewarming, and ischemia/reperfusion injury. A variety of opportunities to overcome these challenge areas were discussed, i.e. preconditioning for enhanced stress tolerance, nanoparticle rewarming, cyroprotectant screening strategies, and the use of cryoprotectant cocktails including ice binding agents.
Pikkarainen, Minna; Korkala, Mikko
Working in the globally distributed market is one of the key trends among the software organizations all over the world. [1-5]. Several factors have contributed to the growth of distributed software development; time-zone independent ”follow the sun” development, access to well-educated labour, maturation of the technical infrastructure and reduced costs are some of the most commonly cited benefits of distributed development [3, 6-8]. Furthermore, customers are often located in different countries because of the companies’ internationalization purposes or good market opportunities.
McIntosh, Andrew M; Stewart, Robert; John, Ann; Smith, Daniel J; Davis, Katrina; Sudlow, Cathie; Corvin, Aiden; Nicodemus, Kristin K; Kingdon, David; Hassan, Lamiece; Hotopf, Matthew; Lawrie, Stephen M; Russ, Tom C; Geddes, John R; Wolpert, Miranda; Wölbert, Eva; Porteous, David J
Data science uses computer science and statistics to extract new knowledge from high-dimensional datasets (ie, those with many different variables and data types). Mental health research, diagnosis, and treatment could benefit from data science that uses cohort studies, genomics, and routine health-care and administrative data. The UK is well placed to trial these approaches through robust NHS-linked data science projects, such as the UK Biobank, Generation Scotland, and the Clinical Record Interactive Search (CRIS) programme. Data science has great potential as a low-cost, high-return catalyst for improved mental health recognition, understanding, support, and outcomes. Lessons learnt from such studies could have global implications.
Full Text Available Unfavorable environmental issues raise attention globally toward the concept of sustainability. Agriculture is not only a sector influenced greatly by environmental conditions, but at the same time, as the most important utilizer of land, a major shaper of the environmental conditions. When forming agricultural policies special attention should be paid to issues such as climate change, scarcity of fresh water, food shortage and biodiversity loss — just to name some of them. The new European general strategy for the upcoming 7 years period has brought new measures for the agricultural policy as well, environment and sustainability being among the top issues.
Thomas C. Mathers
Full Text Available ‘Living fossils’, a phrase first coined by Darwin, are defined as species with limited recent diversification and high morphological stasis over long periods of evolutionary time. Morphological stasis, however, can potentially lead to diversification rates being underestimated. Notostraca, or tadpole shrimps, is an ancient, globally distributed order of branchiopod crustaceans regarded as ‘living fossils’ because their rich fossil record dates back to the early Devonian and their morphology is highly conserved. Recent phylogenetic reconstructions have shown a strong biogeographic signal, suggesting diversification due to continental breakup, and widespread cryptic speciation. However, morphological conservatism makes it difficult to place fossil taxa in a phylogenetic context. Here we reveal for the first time the timing and tempo of tadpole shrimp diversification by inferring a robust multilocus phylogeny of Branchiopoda and applying Bayesian divergence dating techniques using reliable fossil calibrations external to Notostraca. Our results suggest at least two bouts of global radiation in Notostraca, one of them recent, so questioning the validity of the ‘living fossils’ concept in groups where cryptic speciation is widespread.
Farthing, Michael J G
Research misconduct is now acknowledged to be an important global issue for both researchers and the wider community. Guidance on the responsible conduct of research is now widespread, but many are still concerned by the apparent rising tide of serious cases of research misconduct, and perhaps the more worrying widespread presence of questionable research practices. I would suggest that guidance and training, while essential, are not sufficient. Additional interventions, including enhanced monitoring of research outputs and random audit using the available technology should be considered, as should the desirability of having a register of "licensed researchers." In addition, I would support a culture change in the research community in which researchers are encouraged to admit their mistakes; this should be accompanied by a spirit of forgiveness and programmed rehabilitation for the individual concerned. For multiple "premier league" offenders who are reluctant to face their misdemeanors, it is difficult to see how they could continue in the role of a researcher, and their "registration" should be revoked. Research is increasingly undertaken by researchers who cross national boundaries. The globalization of research demands greater collaboration between organizations that are responsible for ensuring standards of research integrity; the need for international standards and guidance has never been greater.
Loftus, Patrick D; Elder, Craig T; D’Ambrosio, Troy; Langell, John T
Graduate medical education has traditionally focused on training future physicians to be outstanding clinicians with basic and clinical science research skills. This focus has resulted in substantial knowledge gains, but a modest return on investment based on direct improvements in clinical care. In today’s shifting healthcare landscape, a number of important challenges must be overcome to not only improve the delivery of healthcare, but to prepare future physicians to think outside the box, ...
Gilbert, Nicole M; O'Brien, Valerie P; Hultgren, Scott; Macones, George; Lewis, Warren G; Lewis, Amanda L
The urinary tract is a common site of infection in humans. During pregnancy, urinary tract infection (UTI) is associated with increased risks of maternal and neonatal morbidity and mortality, even when the infection is asymptomatic. By mapping available rates of UTI in pregnancy across different populations, we emphasize this as a problem of global significance. Many countries with high rates of preterm birth and neonatal mortality also have rates of UTI in pregnancy that exceed rates seen in more developed countries. A global analysis of the etiologies of UTI revealed familiar culprits as well as emerging threats. Screening and treatment of UTI have improved birth outcomes in several more developed countries and would likely improve maternal and neonatal health worldwide. However, challenges of implementation in resource-poor settings must be overcome. We review the nature of the barriers occurring at each step of the screening and treatment pipeline and highlight steps necessary to overcome these obstacles. It is our hope that the information compiled here will increase awareness of the global significance of UTI in maternal and neonatal health and embolden governments, nongovernmental organizations, and researchers to do their part to make urine screening and UTI treatment a reality for all pregnant women.
Lord, Janet E; Suozzi, David; Taylor, Allyn L
This article reviews the contributions of the UN Convention on the Rights of Persons with Disabilities (CRPD) to the progressive development of both international human rights law and global health law and governance. It provides a summary of the global situation of persons with disabilities and outlines the progressive development of international disability standards, noting the salience of the shift from a medical model of disability to a rights-based social model reflected in the CRPD. Thereafter, the article considers the Convention's structure and substantive content, and then analyzes in specific detail the particular contributions of the Convention to health and human rights law and global health governance. It concludes with an exploration of the potential implications of the CRPD's innovations for some of the most pressing issues in global health governance, including the Convention's contributions to the principle of participation in decision-making.
Joshi, P. S.
From jets to cosmos to cosmic censorship P S Joshi Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India E-mail: email@example.com 1. Introduction At the outset, I should like to acknowledge that part of the title above, which tries to capture the main flavour of this meeting, and has been borrowed from one of the plenary talks at the conference. When we set out to make the programme for the conference, we thought of beginning with observations on the Universe, but then we certainly wanted to go further and address deeper questions, which were at the very foundations of our inquiry, and understanding on the nature and structure of the Universe. I believe, we succeeded to a good extent, and it is all here for you in the form of these Conference Proceedings, which have been aptly titled as 'Vishwa Mimansa', which could be possibly translated as 'Analysis of the Universe'! It is my great pleasure and privilege to welcome you all to the ICGC-2011 meeting at Goa. The International Conference on Gravitation and Cosmology (ICGC) series of meetings are being organized by the Indian Association for General Relativity and Gravitation (IAGRG), and the first such meeting was planned and conducted in Goa in 1987, with subsequent meetings taking place at a duration of about four years at various locations in India. So, it was thought appropriate to return to Goa to celebrate the 25 years of the ICGC meetings. The recollections from that first meeting have been recorded elsewhere here in these Proceedings. The research and teaching on gravitation and cosmology was initiated quite early in India, by V V Narlikar at the Banares Hindu University, and by N R Sen in Kolkata in the 1930s. In course of time, this activity grew and gained momentum, and in early 1969, at the felicitation held for the 60 years of V V Narlikar at a conference in Ahmedabad, P C Vaidya proposed the formation of the IAGRG society, with V V Narlikar being the first President. This
Full Text Available This review provides an overview of the current status of the global HIV pandemic and strategies to bring it under control. It updates numerous preventive approaches including behavioral interventions, male circumcision, pre- and post-exposure prophylaxis, vaccines, and microbicides. The manuscript summarizes current anti-retroviral treatment options, their impact in the western world, and difficulties faced by emerging and resource-limited nations in providing and maintaining appropriate treatment regimens. Current clinical and pre-clinical approaches towards a cure for HIV are described, including new drug compounds that target viral reservoirs and gene therapy approaches aimed at altering susceptibility to HIV infection. Recent progress in vaccine development is summarized, including novel approaches and new discoveries.
Nell, Phillip Christopher
This is part of a case series. The case focuses on describing and analysing the environment, profitability and competitiveness of the global pharmaceutical industry, and to evaluate the current and future strategy of Pfizer. It features a large number of tables with quantitative data that help...... solving the case study. The case starts with a short description of recent important events that might mark a turning point for the whole industry. It then focuses on the overall market on drugs - structure, growth, blockbusters, and the influence of national health care systems. Furthermore, firms’ R...... a number of strategic manoeuvres of major players in the last years. At the end, the reader is referred back to the Pfizer situation and Pfizer’s recent strategic initiatives and responses to the market changes....
Ngboawaji Daniel Nte
Full Text Available Times have changed for African cold warrior dictatorships. It used to be that these cold warriors would kill, main and muscle their way into political leadership while the western world and their fellow African state look the other way. Thanks to the multinationals that supported them. The paper examines the political crisis in Togo through the Kantian Democratic Peace Theory. It assumes that the UN, and AU, ECOWAS and the international community are practical example of the Kantian "republican confederation" with overwhelming international political influence to bring pressure upon any one-republican member that threatens world peace. The paper holds that the political crisis in Togo was a threat to both regional and global peace and concludes that international pressure was responsible for the resignation of Faure Eyadema hence the restoration of constitutional order in Togo.
Full Text Available In the article the causes and macroeconomic peculiarities of the formation and operation of international regional economic associations of various forms have been studied. A hierarchical classification of modern international regional economic integration groups is presented. The contribution of the world’s largest integration groups to the global GDP has been analyzed. The main macroeconomic results of countries’ participation in integration associations of different forms on the pre-establishment and post-establishment stages have been described, the positive effects obtained by countries in the result of introduction of certain common economic activity conditions have been determined. Potential risks for Ukraine related to European Integration and prospective positive effects of integration into the world economy have been determined. Conceptual principles of state policy of blocking of the potential risks of international regional economic integration for Ukraine have been substantiated.
Desai, Sachin N; Pezzoli, Lorenzo; Alberti, Kathryn P; Martin, Stephen; Costa, Alejandro; Perea, William; Legros, Dominique
Cholera remains an important but neglected public health threat, affecting the health of the poorest populations and imposing substantial costs on public health systems. Cholera can be eliminated where access to clean water, sanitation, and satisfactory hygiene practices are sustained, but major improvements in infrastructure continue to be a distant goal. New developments and trends of cholera disease burden, the creation of an affordable cholera vaccine for use in developing countries, as well as recent evidence of vaccination impact has created an increased demand for oral cholera vaccine (OCV). The global OCV stockpile was established in 2013 and with support from Gavi, has assisted in achieving rapid access to vaccine in emergencies. Recent WHO prequalification of a second affordable OCV supports the stockpile goals of increased availability and distribution to affected populations. It serves as an essential step towards an integrated cholera control and prevention strategy in emergency and endemic settings.
Battiti, Roberto; Sergeyev, Yaroslav; Brunato, Mauro; Kvasov, Dmitri
While comparing results on benchmark functions is a widely used practice to demonstrate the competitiveness of global optimization algorithms, fixed benchmarks can lead to a negative data mining process. To avoid this negative effect, the GENOPT contest benchmarks can be used which are based on randomized function generators, designed for scientific experiments, with fixed statistical characteristics but individual variation of the generated instances. The generators are available to participants for off-line tests and online tuning schemes, but the final competition is based on random seeds communicated in the last phase through a cooperative process. A brief presentation and discussion of the methods and results obtained in the framework of the GENOPT contest are given in this contribution.
Sarkar, Sudipta; Greenleaf, John E; Gupta, Anirban; Uy, Davin; Sengupta, Arup K
Millions of people around the world are currently living under the threat of developing serious health problems owing to ingestion of dangerous concentrations of arsenic through their drinking water. In many places, treatment of arsenic-contaminated water is an urgent necessity owing to a lack of safe alternative sources. Sustainable production of arsenic-safe water from an arsenic-contaminated raw water source is currently a challenge. Despite the successful development in the laboratory of technologies for arsenic remediation, few have been successful in the field. A sustainable arsenic-remediation technology should be robust, composed of local resources, and user-friendly as well as must attach special consideration to the social, economic, cultural, traditional, and environmental aspects of the target community. One such technology is in operation on the Indian subcontinent. Wide-scale replication of this technology with adequate improvisation can solve the arsenic crisis prevalent in the developing world.
Petersen, Nils Braad; Kampf, Constance Elizabeth
The literature on virtual teams describes knowledge sharing and trust-building challenges. However, few studies take into account the complexity of the work context in these virtual teams. Key factors affecting complexity include situations in which employees are involved in several teams...... and projects simultaneously; some virtual, some co-located. This multi-team membership complicates relationship-building within each individual team. To understand how employees make sense of this complex, or equivocal (Weick, 2001) environment, this paper adopts a discourse perspective combining Austin...... organization to circumvent organizational strategic discourse. In this process, they build teams and communities based on trusted weak ties (Granovetter, 1973; Levin & Cross, 2004). Furthermore, the study shows how difficult it can be for management to listen in on and react to this discourse change...
Avritzer, Alberto; Bronsard, Francois; Matos, Gilberto
Global development promises important productivity and capability advantages over centralized work by optimally allocating tasks according to locality, expertise or cost. All too often, global development also introduces a different set of communication and coordination challenges that can negate all the expected benefits and even cause project failures. Most common problems have to do with building trust or quick feedback loops between distributed teams, or with the integration of globally developed components. Agile processes tend to emphasize the intensity of communication, and would seem to be negatively impacted by team distribution. In our experience, these challenges can be overcome, and agile processes can address some of the pitfalls of global development more effectively than plan-driven development. This chapter discusses how to address the difficulties faced when adapting agile processes to global development and the improvements to global development that adopting agile can produce.
Smylie, Janet; Firestone, Michelle
Canada is known internationally for excellence in both the quality and public policy relevance of its health and social statistics. There is a double standard however with respect to the relevance and quality of statistics for Indigenous populations in Canada. Indigenous specific health and social statistics gathering is informed by unique ethical, rights-based, policy and practice imperatives regarding the need for Indigenous participation and leadership in Indigenous data processes throughout the spectrum of indicator development, data collection, management, analysis and use. We demonstrate how current Indigenous data quality challenges including misclassification errors and non-response bias systematically contribute to a significant underestimate of inequities in health determinants, health status, and health care access between Indigenous and non-Indigenous people in Canada. The major quality challenge underlying these errors and biases is the lack of Indigenous specific identifiers that are consistent and relevant in major health and social data sources. The recent removal of an Indigenous identity question from the Canadian census has resulted in further deterioration of an already suboptimal system. A revision of core health data sources to include relevant, consistent, and inclusive Indigenous self-identification is urgently required. These changes need to be carried out in partnership with Indigenous peoples and their representative and governing organizations.
Vijay Kumar Chattu
Full Text Available The theme for World Health Day campaign for this year 2015 is “Food safety: from farm to plate, make food safe”. The day focuses on demonstrating the importance of food safety along the whole length of the food chain in a globalized world, from production and transport, to preparation and consumption (1. Everyone needs food and needs it every day either plant sources or animal sources or both. The food we eat must be nutritious and safe but we often ignore or overlook the issue of food safety. Many cases of food borne diseases either acute poisoning or chronic exposure are largely under reported. In this globalized world, though the food chain extends over thousands of miles from different continents, an error or contamination in one country can affect the health of consumers on the other part of the world. To ensure full impact, these actions must build on principles of government stewardship, engagement of civil society, (2.According to UN, access to a safe and secure food supply is a basic human right. Food safety and food security are interrelated concepts which have an impact on the health outcomes and quality of human lives. As per Food and Agricultural Organization (FAO, Food security is a situation that exists when all people, at all times, have physical, social and economic access to sufficient, safe and nutritious food that meets their dietary needs and food preferences for an active and healthy life, (3. Based on the definition of Food security, four food security dimensions can be identified: food availability, economic and physical access to food, food utilization and stability over time. Apart from that food security is also affected by Poverty and Climate change.Food safety is an umbrella term that encompasses many aspects like food items handling, preparation and storage of food to prevent illness and injury. The other important issues are chemical, microphysical and microbiological aspects of food safety, (4. Control of
Ishida, K.; Nishibori, F. (Kansai Environmental Engineering Center Co. Ltd., Osaka (Japan))
This paper summarizes themes on issues on global environment that Kansai Environmental Engineering Center Co., Ltd. has been commissioned for study. The themes may be listed as follows: transportation, fixation, and deposition of CO2 in the north-west Pacific sea area; development of carbon circulation model; effects of oceans on atmospheric CO2 increase; measurement of chemical substances dissolved in sea water; CO2 photosynthesis with algae; proliferation conditions for Haptophyceae algae and calcification capability of CO2; carbon fixing mechanisms and calcification capability of shellfish; and growth acceleration of trees by utilizing mushroom hyphae, and afforestation techniques. The investigation on the mechanism of circulating carbons in ocean has provided the following results: a low-salt sea area exists as a water mass distribution that has 34.2 psu or lower in a depth of 500 m from 45 degrees to 15 degrees north latitude; the CO2 partial pressure in air on sea surface and in sea water is lower in the sea water (CO2 absorption region) than in the air from 45 degrees to 40 degrees north latitude and 8 degrees and lower in south latitude; total carbon distribution is lower in the surface layer, and the higher the deeper; phytoplanktons are distributed densely in areas with nutrient salt at somewhat lower levels; and planktons with sizes of 10 micrometer or smaller and 300 micrometer or larger are prevalent in the equatorial regions. 4 figs., 1 tab.
Full Text Available The present chaotic transformation from the industrial to the global information society is accelerating the ecological, social and economic unsustainability. The rapidly growing unsustainable, fossil energy powered urbanindustrial technosphere and their detrimental impacts on nature and human well-being are threatening the solar energy powered natural and seminatural biosphere landscapes and their vital ecosystem services. A sustainability revolution is therefore urgently needed, requiring a shift from the „fossil age“ to the „solar age“ of a new world economy, coupled with more sustainable lifestyles and consumption patterns. The sustainable future of viable multifunctional biosphere landscapes of the Mediterranean Region and elsewhere and their biological and cultural richness can only be ensured by a post-industrial symbiosis between nature and human society. For this purpose a mindset shift of scientists and professionals from narrow disciplinarity to transdisciplinarity is necessary, dealing with holistic land use planning and management, in close cooperation with land users and stakeholders. To conserve and restore the rapidly vanishing and degrading Mediterranean uplands and highest biological ecological and cultural landscape ecodiversity, their dynamic homeorhetic flow equilibrium, has to be maintained by continuing or simulating all anthropogenic processes of grazing, browsing by wild and domesticated ungulates. Catastrophic wildfires can be prevented only by active fire and fuel management, converting highly inflammable pine forests and dense shrub thickets into floristically enriched, multi- layered open woodlands and recreation forests.
The air transport policies of small states are currently at a crossroad. Policy makers in these countries are facing a difficult dilemma: either follow the general trend of liberalization and pay the high cost of the resulting restructuring or maintain the existing regulatory and ownership structures at the risk of isolation thus undermining the viability and sustainability of their air transport sector and their economies in general. This paper proposes to explore the broad issues raised by this difficult dilemma, to outline its special significance in the context of small states and to delineate the options opened to the economic policymakers; in these states. After a brief note on the method of research, we sketch the main elements of the international air transport industry in which the airlines of small states are called upon to act. We then propose to review the main features of the analytical framework of this debate as it pertains to the special circumstances of these states. Then we focus on the challenges facing the airlines of Small States, while the next section proposes a number of the alternative policy options open to the policy makers in these states. The main conclusions are drawn in the final section.
It is widely agreed that the concentration of greenhouse gases in the earth`s atmosphere is increasing, that this increase is a consequence of man`s activities, and that there is significant risk that this will lead to changes in the earth`s climate. The question is now being discussed what, if anything, we should be doing to minimize and/or adapt to changes in climate. Virtually every statement on this matter; from the US Office of Technology Assessment, to the National Academy of Science, to the Nairobi Declaration on Climatic Change, includes some recommendation for planting and protecting forests. In fact, forestry is intimately involved in the climate change debate for several reasons: changing climate patterns will affect existing forests, tropical deforestation is one of the major sources of greenhouse gases to the atmosphere, reforestation projects could remove additional carbon dioxide from the atmosphere and there is renewed interest in wood-based or other renewable fuels to replace fossil fuels. Part of the enthusiasm for forestry-related strategies in a greenhouse context is the perception that forests not only provide greenhouse benefits but also serve other desirable social objectives. This discussion will explore the current range of thinking in this area and try to stimulate additional thinking on the rationality of the forestry-based approaches and the challenges posed for US forestry.
Eberlein, B. [York Univ., Toronto, ON (Canada). Schulich School of Business; Doern, G.B. [Carleton Univ., Ottawa, ON (Canada). School of Public Policy and Administration; Exeter Univ., (United Kingdom). Dept. of Politics] (eds.)
This book features essays by leading energy and public policy specialists from Canada and Germany. It originated in the Transatlantic Energy Conference which was hosted by the Canadian Centre for German and European Studies at Toronto's York University in September 2005. The conference was attended by leading energy scholars and experts from Canadian and European universities, research institutes and governmental and non-governmental organizations. The purpose of this book was to compare the dynamics of multi-level energy regulatory governance in Germany and Canada, notably the energy policy challenges that include energy security, environmental sustainability and a competitive resource economy. Many strategies to produce more efficient and sustainable energy are presented in the book. Part 1 of the book focuses on the energy industry, with particular emphasise on electricity, nuclear energy and natural gas. Part 2 of the book focuses on domestic patterns of multi-level energy governance and regulation in the two countries. As a member of the European Union, Germany is more advanced in dealing with multi-level governmental and sustainability constraints than Canada is as a member of the North American Free Trade Agreement (NAFTA). The book focuses on the influence that the energy sector and multi-level institutional arrangements have on energy governance, with particular attention to the link between environmental study, climate change issues and economic market reforms. The growing differences between NAFTA and European Union member countries were highlighted. refs., tabs., figs.
Gleadow, R.; O'Leary, B.; Burd, M.
National parks and nature reserves are set aside to preserve certain ecosystems, reflecting species distributions at a moment in time. Changing climate and fire dynamics can mean that the species most suited to that area are different, leading new tree species to 'invade' the conservation areas. Pittosporum undulatum is an invasive tree native tree species with a natural range from southeast Queensland to Eastern Victoria, Australia. Soon after European settlement this species became a popular ornamental tree in gardens and was planted outside of its natural range across the continent and introduced to the USA (where it is known as Victorian Box), the Hawaiian Islands, Jamaica, southern Africa and the Azores. The reason this is important is because high density of P. undulatum lead to reduced biodiversity and often the complete suppression of regeneration of exiting forest trees. In Australia, changes in fire dynamics have played a major part in its in dominance. New strategies for forest management were proposed by Gleadow an Ashton in the 1980s, but lack of action has led us to predict that the entire Dandenong Ranges, near Melbourne, will be invaded within 25 years resulting in the loss of a major recreational and conservation area. This is a model of the type of problems that can be expected as the climate envelope for species changes in the coming century, challenging the very concept of a "native ".
Sultana, Razia; Christ, Andreas; Feisst, Markus; Curticapean, Dan
Nowadays, it is assumed of many applications, companies and parts of the society to be always available online. However, according to [Times, Oct, 31 2011], 73% of the world population do not use the internet and thus aren't "online" at all. The most common reasons for not being "online" are expensive personal computer equipment and high costs for data connections, especially in developing countries that comprise most of the world's population (e.g. parts of Africa, Asia, Central and South America). However it seems that these countries are leap-frogging the "PC and landline" age and moving directly to the "mobile" age. Decreasing prices for smart phones with internet connectivity and PC-like operating systems make it more affordable for these parts of the world population to join the "always-online" community. Storing learning content in a way accessible to everyone, including mobile and smart phones, seems therefore to be beneficial. This way, learning content can be accessed by personal computers as well as by mobile and smart phones and thus be accessible for a big range of devices and users. A new trend in the Internet technologies is to go to "the cloud". This paper discusses the changes, challenges and risks of storing learning content in the "cloud". The experiences were gathered during the evaluation of the necessary changes in order to make our solutions and systems "cloud-ready".
Ladies and Gentlemen, It is an honor for me to present my welcome address in the 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3), as the president of Kanto Gakuin University. Particularly to those from abroad more than 17 countries, I am very grateful for your participation after long long trips from your home to Yokohama. On the behalf of the Kanto Gakuin University, we certainly welcome your visit to our university and stay in Yokohama. First I would like to introduce Kanto Gakuin University briefly. Kanto Gakuin University, which is called KGU, traces its roots back to the Yokohama Baptist Seminary founded in 1884 in Yamate, Yokohama. The seminary's founder was Albert Arnold Bennett, alumnus of Brown University, who came to Japan from the United States to establish a theological seminary for cultivating and training Japanese missionaries. Now KGU is a major member of the Kanto Gakuin School Corporation, which is composed of two kindergartens, two primary schools, two junior high schools, two senior high schools as well as KGU. In this university, we have eight faculties with graduate school including Humanities, Economics, Law, Sciences and Engineering, Architecture and Environmental Design, Human and Environmental Studies, Nursing, and Law School. Over eleven thousands students are currently learning in our university. By the way, my major is the geotechnical engineering, and I belong to the faculty of Sciences and Engineering in my university. Prof. T. Yamada, here, is my colleague in the same faculty. I know that the nuclear physics is one of the most active academic fields in the world. In fact, about half of the participants, namely, more than 50 scientists, come from abroad in this conference. Moreover, I know that the nuclear physics is related to not only the other fundamental physics such as the elementary particle physics and astrophysics but also chemistry, medical sciences, medical cares, and radiation metrology
Fanning, A; Billo, N; Tannenbaum, T; Phypers, M; Little, C; Graham, B; Mill, J
The Stop TB Partnership has engaged the 22 high-burden countries in a drive toward the goal of finding 70% of cases and curing 85% by 2005. Traditional partners, aid agencies and governments of industrialised nations have joined the Partnership, but the broader range of civil society remains outside the discourse, risking disinterest on the part of the donor community. Stop TB-Halte à la Tuberculose-Canada was organised to engage new partners to support the Canadian government's commitment to the goal of reducing poverty and diseases of poverty, including tuberculosis, by 50% by 2010. The successes and challenges are explored, and the possibility raised that having a Stop TB movement in every country will ensure that support is sustained and goals of global tuberculosis control reached.
Occupational health services (OHS) have developed together with other social protection measures in response to the challenges of the Industrial Revolution and associated demographic changes of the 19th century. They were perceived as necessary and often even initiated by industry. Their organization and tasks are defined by tripartite international labor law which is largely reflected in national legislations. Increasing global trade and competition based on new technology, have changed not only occupational hazards, but also resulted in a considerable shift of power from national states to corporate enterprises as visible also from increasing deregulation. The development requires adaptation from both, OHS and enterprises, in the best interest of a healthy and productive workforce, of social and economic stability, and of sustainability.
Full Text Available Teachers are being asked to manage a specific didactic situation which falls into the category of what we have proposed to call “socially acute questions (SAQs”. A SAQ is a question which is acute in society, in background knowledge and in knowledge taught. Thus, teaching SAQs demands socio-epistemological reflexivity in the processes of knowledge production and in the social conditions in which this knowledge emerges; teaching SAQs will give priority to interdisciplinary, scientific and ethical reasoning. The split between ideology and science can certainly be examined when considering a socially acute question which is the subject of debate in society. In the example of the globalization taught: the diversity of analysis in the economic domain gives rise to great uncertainty because it justifies practically opposing policies; within a transdisciplinary framework, the globalization includes concepts, ideologies or social practices in a double movement of standardization and differentiation. By way of SAQs, we have attempted to show that learning stakes are numerous. However didactic choices must be supported by socio-epistemological survey, the identification of an epistemological posture and the definition of a didactic strategy.Les enseignants sont appelés à gérer une situation didactique spécifique dans l’enseignement des «questions socialement vives (QSV ». Les QSV sont des questions qui donnent lieu à débat dans la société, dans les savoirs scientifiques et dans l’enseignement. Ainsi, l‘enseignement des QSV nécessite une réflexivité socio-épistémologique dans le processus de production du savoir et dans les conditions sociales d’émergence de ces savoirs; l’enseignement des QSV donnera la priorité au raisonnement interdisciplinaire, scientifique et éthique. La scission entre l‘idéologie et la science peut être examinée lors de l‘examen d‘une QSV qui fait l‘objet d‘un débat dans la soci
Building a global health education network for clinical care and research. The benefits and challenges of distance learning tools. Lessons learned from the Hopkins Center for Clinical Global Health Education.
Bollinger, Robert C; McKenzie-White, Jane; Gupta, Amita
Expanding the capacity for clinical care and health research is a global priority and a global challenge. The Johns Hopkins Center for Clinical Global Health Education (CCGHE) was established in 2005 to provide access to high-quality training to health care providers in resource-limited settings. The CCGHE made a strategic decision to develop, use, and evaluate distance learning platforms to achieve its mission. In the initial years of this new program, several lessons have been learned that may be helpful to other programs considering the use of distance learning programs to expand global health clinical and research capacity.