WorldWideScience

Sample records for address global challenges

  1. Cooperation of international Research Infrastructures to address environmental global challenges

    Science.gov (United States)

    Bonet García, Francisco J.; Suárez-Muñoz, María; Conchubhair, Diarmuid O.; Dohna, Tina; Lo Bue, Nadia

    2017-04-01

    Human impact on the planet is causing a set of global environmental problems that threaten the wellbeing of current and future generations. Examples of these environmental problems include climate change, decline of biodiversity, alteration of biogeochemical cycles, ocean acidification, etc. These environmental Global Challenges (GCs) are transnational and complex, combining elements of both natural and social factors. Providing solutions for these challenges can be significantly enhanced through the collaboration of various related institutions, governments and stakeholders. A deeper understanding of the causes and consequences of GCs, as well as the processes which control them is required. Environmental Research Infrastructures (DANUBIUS-RI) are key players in this learning process. Covering many fields of research, it is through RIs collaboration that GCs can be more fully addressed. However, the collaboration among environmental RIs is still limited nationally as well as internationally. Although contact is encouraged and interactions are common practice, there are few cases where RI managers initiate and foster transnational collaborations in order to address specific problems. The COOP+ project aims to explore and strengthen cooperation among global RIs by bringing various RIs together and working on the identification of requirements, strengths, knowledge gaps and other relevant items in regard to the selected GCs. For this purpose, 13 GCs have been selected: coral bleaching, marine debris, noise impact on marine fauna, Arctic sea ice melting, pollinators decline, threatened species, agriculture pollutants, nitrogen cycle, carbon and GHG, geohazards and extreme events, estuaries, global urbanization process, and ozone depletion. These GCs are being analysed and described by multidisciplinary teams of experts composed of scientists, RIs operators and other stakeholders. This assessment will derive a list of tasks and requirements to be fulfilled by the

  2. Addressing global change challenges for Central Asian socio-ecosystems

    Institute of Scientific and Technical Information of China (English)

    Jiaguo QI; Temirbek S.BOBUSHEV; Rashid KULMATOV; Pavel GROISMAN; Garik GUTMAN

    2012-01-01

    Central Asia is one of the most vulnerable regions on the planet earth to global climate change,depending on very fragile natural resources.The Soviet legacy has left the five countries (Kazakhstan,Tajikistan,Kyrgyzstan,Turkmenistan,and Uzbekistan) with a highly integrated system but they are facing great challenges with tensions that hinder regional coordination of food and water resources.With increasing climate variability and warming trend in the region,food and water security issues become even more crucial now and,if not addressed properly,could affect the regional stability.The long-term drivers of these two most critical elements,food and water,are climate change; the immediate and probably more drastic factors affecting the food and water security are land uses driven by institutional change and economic incentives.As a feedback,changes in land use and land cover have directly implications on water uses,food production,and lifestyles of the rural community in the region.Regional and international efforts have been made to holistically understand the cause,extent,rate and societal implications of land use changes in the region.Much of these have been understood,or under investigation by various projects,but solutions or research effort to develop solutions,to these urgent regional issues are lacking.This article,serves as an introduction to the special issue,provides a brief overview of the challenges facing the Central Asian countries and various international efforts in place that resulted in the publications of this special issue.

  3. Biomimetic Nanotechnology: A Powerful Means to address Global Challenges

    CERN Document Server

    Gebeshuber, Ille C

    2010-01-01

    Biomimetic nanotechnology is a prominent research area at the meeting place of life sciences with engineering and physics: it is a continuously growing field that deals with knowledge transfer from biology to nanotechnology. Biomimetic nanotechnology is a field that has the potential to substantially support successful mastering of major global challenges. The Millennium Project was commissioned by the United Nations Secretary-General in 2002 to develop a concrete action plan for the world to reverse the grinding poverty, hunger and disease affecting billions of people. It states 15 Global Challenges: sustainable development, water, population and resources, democratization, long-term perspectives, information technology, the rich-poor gap, health, capacity to decide, peace and conflict, status of women, transnational crime, energy, science and technology and global ethics. The possible contributions to master these challenges with the help of biomimetic nanotechnology will be discussed in detail.

  4. Ecological Intensification: Local Innovation to Address Global Challenges

    NARCIS (Netherlands)

    Tittonell, P.A.; Klerkx, L.W.A.; Baudron, F.; Félix, G.F.; Ruggia, A.P.; Apeldoorn, van D.F.; Dogliotti, S.; Mapfumo, Paul; Rossing, W.A.H.

    2016-01-01

    The debate on future global food security is centered on increasing yields. This focus on availability of food is overshadowing access and utilization of food, and the stability of these over time. In addition, pleas for increasing yields across the board overlook the diversity of current positions

  5. Ecological Intensification: Local Innovation to Address Global Challenges

    NARCIS (Netherlands)

    Tittonell, P.A.; Klerkx, L.W.A.; Baudron, F.; Félix, G.F.; Ruggia, A.P.; Apeldoorn, van D.F.; Dogliotti, S.; Mapfumo, Paul; Rossing, W.A.H.

    2016-01-01

    The debate on future global food security is centered on increasing yields. This focus on availability of food is overshadowing access and utilization of food, and the stability of these over time. In addition, pleas for increasing yields across the board overlook the diversity of current positions

  6. Addressing Global Environmental Challenges through Interdisciplinary Biogeochemical Research

    Science.gov (United States)

    Paytan, A.

    2013-12-01

    Our planet is dynamic; energy and matter constantly move between the hydrosphere, atmosphere and lithosphere on time scales from seconds to millenia. These tight interactions - including those between organisms and their physical environment - are what make Earth habitable. However, as Rachel Carson wrote, 'Only within the moment of time represented by the present century has one species - man - acquired significant power to alter the nature of this world'. Globalization and explosive population growth have generated far-reaching environmental problems on a scale that humanity has never faced before. Fortunately, our species has also developed an unprecedented ability to provide science-based solutions. Since processes impacting the environment involve complex biological, physical, chemical and geological interactions and feedbacks, they require the integration of expertise from all these scientific disciplines as well as input from policy makers, social scientists, and economists. This talk presents four examples of current interdisciplinary research projects conducted in my lab, each one related to a theme from one of Carson's books (Under the Sea-wind, The Sea Around Us, The Edge of the Sea, and Silent Spring). These projects, and others like them, provide hope that we can move toward a sustainable relationship with the natural world by encouraging the best scientists to conduct interdisciplinary research with direct applications for environmental management and stewardship.

  7. Global challenges keynote address in memoriam to colleagues lost in the Malaysia airlines 17 crash

    Science.gov (United States)

    Hankins, Catherine A.

    2016-01-01

    ABSTRACT Six colleagues working in the HIV field were killed when their flight en route to Kuala Lumpur was shot down over the Ukraine. This report is drawn from the in memoriam keynote opening address given at the 12th International AIDS Impact conference in Amsterdam in 2015. It highlights their tangible and valued roles in the HIV response and looks forward to the road ahead. It describes the ways in which we can build on their legacy to address current global challenges in HIV prevention and treatment and to mobilise the intensified, focused resources that are needed to turn the HIV epidemic on its head. PMID:26963879

  8. Global challenges keynote address in memoriam to colleagues lost in the Malaysia airlines 17 crash.

    Science.gov (United States)

    Hankins, Catherine A

    2016-01-01

    Six colleagues working in the HIV field were killed when their flight en route to Kuala Lumpur was shot down over the Ukraine. This report is drawn from the in memoriam keynote opening address given at the 12th International AIDS Impact conference in Amsterdam in 2015. It highlights their tangible and valued roles in the HIV response and looks forward to the road ahead. It describes the ways in which we can build on their legacy to address current global challenges in HIV prevention and treatment and to mobilise the intensified, focused resources that are needed to turn the HIV epidemic on its head.

  9. COOP+ project: Promoting the cooperation among international Research Infrastructures to address global environmental challenges.

    Science.gov (United States)

    Bonet-García, Francisco; Materia, Paola; Kutsch, Werner; de Lucas, Jesús Marco; Tjulin, Anders

    2016-04-01

    During the Anthropocene, mankind will face several global environmental challenges. One of the first and more successful responses provided by Science to these challenges is the collecting of long-term series of biophysical variables in order to improve our knowledge of natural systems. The huge amount of information gathered during the last decades by Research Infrastructures (RIs) has helped to understand the structure and functioning of natural systems at local and regional scales. But how can we address the global cross-scale and cross-disciplinary challenges posed by the global environment change? We believe that it will be necessary to observe, model better and understand the whole biosphere using long term data generated by international RIs. RIs play a key role on many of the last advances and discoveries in science, from the observation of the Higgs Boson at CERN to the exploration of the Universe by the telescopes of the European Southern Observatory in Chile. The scale of complexity, instrumentation, computing resources, technological advances, and also of the investments, and the size of research collaborations, do not have precedents in Science. RIs in environmental field are developing fast, but the corresponding communities need yet to further reflect the need for a wider global collaboration because the challenges to tackle are in essence of global nature. This contribution describes how COOP+ project (EU Horizon 2020 Coordination and Support Action) will promote the cooperation among RIs at a global scale to address global environmental challenges. Our project evolves from the experience of the sucessful FP7 COOPEUS project (see http://www.coopeus.eu), which explored the use and access to data from RIs in environmental research in Europe and USA. The general goal of COOP+ is to strengthen the links and coordination of the ESFRI RIs related to Marine Science (EMSO), Arctic and Atmospheric Research (EISCAT), Carbon Observation (ICOS) and Biodiversity

  10. The importance of fungi and mycology for addressing major global challenges*.

    Science.gov (United States)

    Lange, Lene

    2014-12-01

    In the new bioeconomy, fungi play a very important role in addressing major global challenges, being instrumental for improved resource efficiency, making renewable substitutes for products from fossil resources, upgrading waste streams to valuable food and feed ingredients, counteracting life-style diseases and antibiotic resistance through strengthening the gut biota, making crop plants more robust to survive climate change conditions, and functioning as host organisms for production of new biological drugs. This range of new uses of fungi all stand on the shoulders of the efforts of mycologists over generations: the scientific discipline mycology has built comprehensive understanding within fungal biodiversity, classification, evolution, genetics, physiology, ecology, pathogenesis, and nutrition. Applied mycology could not make progress without this platform. To unfold the full potentials of what fungi can do for both environment and man we need to strengthen the field of mycology on a global scale. The current mission statement gives an overview of where we are, what needs to be done, what obstacles to overcome, and which potentials are within reach. It further provides a vision for how mycology can be strengthened: The time is right to make the world aware of the immense importance of fungi and mycology for sustainable global development, where land, water and biological materials are used in a more efficient and more sustainable manner. This is an opportunity for profiling mycology by narrating the role played by fungi in the bioeconomy. Greater awareness and appreciation of the role of fungi can be used to build support for mycology around the world. Support will attract more talent to our field of study, empower mycologists around the world to generate more funds for necessary basic research, and strengthen the global mycology network. The use of fungi for unlocking the full potentials of the bioeconomy relies on such progress. The fungal kingdom can be an

  11. Addressing the "Global Health Tax" and "Wild Cards": Practical Challenges to Building Academic Careers in Global Health.

    Science.gov (United States)

    Palazuelos, Daniel; Dhillon, Ranu

    2016-01-01

    Among many possible benefits, global health efforts can expand the skills and experience of U.S. clinicians, improve health for communities in need, and generate innovations in care delivery with relevance everywhere. Yet, despite high rates of interest among students and medical trainees to include global health opportunities in their training, there is still no clear understanding of how this interest will translate into viable and sustained global health careers after graduation. Building on a growing conversation about how to support careers in academic global health, this Perspective describes the practical challenges faced by physicians pursuing these careers after they complete training. Writing from their perspective as junior faculty at one U.S. academic health center with a dedicated focus on global health training, the authors describe a number of practical issues they have found to be critical both for their own career development and for the advice they provide their mentees. With a particular emphasis on the financial, personal, professional, and logistical challenges that young "expat" global health physicians in academic institutions face, they underscore the importance of finding ways to support these career paths, and propose possible solutions. Such investments would not only respond to the rational and moral imperatives of global health work and advance the mission of improving human health but also help to fully leverage the potential of what is already an unprecedented movement within academic medicine.

  12. The Challenges Facing the Multilateral Trading System in Addressing Global Public Policy Objectives

    Directory of Open Access Journals (Sweden)

    Christophe Bellmann

    2013-02-01

    Full Text Available Despite a record-breaking 14.5 per cent increase in world merchandise exports, the effects of the financial crisis and global recession are still hampering faster economic recovery. Relatively high oil prices combined with persistent unemployment and measures designed to reduce budget deficits have undermined short-term growth prospects. While South–South trade continues to explode, trade imbalances – i.e. the gap between exports and imports – widened in 2010 compared to 2009 (though smaller than pre-crisis levels. Meanwhile, trade negotiations under the Doha Round have reached an impasse, generating uncertainties about the future of the World Trade Organization (WTO as a negotiating forum. Under these circumstances, should the system rethink its decision-making process founded upon the predominance of member states, the principle of consensus and the notion of single undertaking, as some critics have suggested? And, if so, how could such a reform agenda be initiated at the WTO? Moreover, beyond the negotiating function of the WTO, the paralysis of the system also raises urgent questions about the ability of the system to respond to pressing challenges of our times, such as trade and climate change, or food security and price volatility.

  13. Next biotech plants: new traits, crops, developers and technologies for addressing global challenges.

    Science.gov (United States)

    Ricroch, Agnès E; Hénard-Damave, Marie-Cécile

    2016-08-01

    Most of the genetically modified (GM) plants currently commercialized encompass a handful of crop species (soybean, corn, cotton and canola) with agronomic characters (traits) directed against some biotic stresses (pest resistance, herbicide tolerance or both) and created by multinational companies. The same crops with agronomic traits already on the market today will continue to be commercialized, but there will be also a wider range of species with combined traits. The timeframe anticipated for market release of the next biotech plants will not only depend on science progress in research and development (R&D) in laboratories and fields, but also primarily on how demanding regulatory requirements are in countries where marketing approvals are pending. Regulatory constraints, including environmental and health impact assessments, have increased significantly in the past decades, delaying approvals and increasing their costs. This has sometimes discouraged public research entities and small and medium size plant breeding companies from using biotechnology and given preference to other technologies, not as stringently regulated. Nevertheless, R&D programs are flourishing in developing countries, boosted by the necessity to meet the global challenges that are food security of a booming world population while mitigating climate change impacts. Biotechnology is an instrument at the service of these imperatives and a wide variety of plants are currently tested for their high yield despite biotic and abiotic stresses. Many plants with higher water or nitrogen use efficiency, tolerant to cold, salinity or water submergence are being developed. Food security is not only a question of quantity but also of quality of agricultural and food products, to be available and accessible for the ones who need it the most. Many biotech plants (especially staple food) are therefore being developed with nutritional traits, such as biofortification in vitamins and metals. The main

  14. Addressing the terawatt challenge

    DEFF Research Database (Denmark)

    Vesborg, Peter C. K.; Jaramillo, Thomas F.

    2012-01-01

    The energy infrastructure for fossil fuels is well-established, accounting for approximately 87% of the 16 TW of power consumed globally. For renewable and sustainable energy conversion technologies to play a relevant role at the terrestrial scale, they must be able to scale to the TW level...... of deployment. This would place a significant demand on the current and future supply of raw materials (chemical elements) used by those technologies. Oftentimes, the average crustal abundance of a chemical element is cited as a measure of its scalability, however another important metric for scalability...

  15. Addressing the workforce pipeline challenge

    Energy Technology Data Exchange (ETDEWEB)

    Leonard Bond; Kevin Kostelnik; Richard Holman

    2006-11-01

    A secure and affordable energy supply is essential for achieving U.S. national security, in continuing U.S. prosperity and in laying the foundations to enable future economic growth. To meet this goal the next generation energy workforce in the U.S., in particular those needed to support instrumentation, controls and advanced operations and maintenance, is a critical element. The workforce is aging and a new workforce pipeline, to support both current generation and new build has yet to be established. The paper reviews the challenges and some actions being taken to address this need.

  16. A biodiversity indicators dashboard: addressing challenges to monitoring progress towards the Aichi biodiversity targets using disaggregated global data.

    Directory of Open Access Journals (Sweden)

    Xuemei Han

    Full Text Available Recognizing the imperiled status of biodiversity and its benefit to human well-being, the world's governments committed in 2010 to take effective and urgent action to halt biodiversity loss through the Convention on Biological Diversity's "Aichi Targets". These targets, and many conservation programs, require monitoring to assess progress toward specific goals. However, comprehensive and easily understood information on biodiversity trends at appropriate spatial scales is often not available to the policy makers, managers, and scientists who require it. We surveyed conservation stakeholders in three geographically diverse regions of critical biodiversity concern (the Tropical Andes, the African Great Lakes, and the Greater Mekong and found high demand for biodiversity indicator information but uneven availability. To begin to address this need, we present a biodiversity "dashboard"--a visualization of biodiversity indicators designed to enable tracking of biodiversity and conservation performance data in a clear, user-friendly format. This builds on previous, more conceptual, indicator work to create an operationalized online interface communicating multiple indicators at multiple spatial scales. We structured this dashboard around the Pressure-State-Response-Benefit framework, selecting four indicators to measure pressure on biodiversity (deforestation rate, state of species (Red List Index, conservation response (protection of key biodiversity areas, and benefits to human populations (freshwater provision. Disaggregating global data, we present dashboard maps and graphics for the three regions surveyed and their component countries. These visualizations provide charts showing regional and national trends and lay the foundation for a web-enabled, interactive biodiversity indicators dashboard. This new tool can help track progress toward the Aichi Targets, support national monitoring and reporting, and inform outcome-based policy-making for the

  17. A biodiversity indicators dashboard: addressing challenges to monitoring progress towards the Aichi biodiversity targets using disaggregated global data.

    Science.gov (United States)

    Han, Xuemei; Smyth, Regan L; Young, Bruce E; Brooks, Thomas M; Sánchez de Lozada, Alexandra; Bubb, Philip; Butchart, Stuart H M; Larsen, Frank W; Hamilton, Healy; Hansen, Matthew C; Turner, Will R

    2014-01-01

    Recognizing the imperiled status of biodiversity and its benefit to human well-being, the world's governments committed in 2010 to take effective and urgent action to halt biodiversity loss through the Convention on Biological Diversity's "Aichi Targets". These targets, and many conservation programs, require monitoring to assess progress toward specific goals. However, comprehensive and easily understood information on biodiversity trends at appropriate spatial scales is often not available to the policy makers, managers, and scientists who require it. We surveyed conservation stakeholders in three geographically diverse regions of critical biodiversity concern (the Tropical Andes, the African Great Lakes, and the Greater Mekong) and found high demand for biodiversity indicator information but uneven availability. To begin to address this need, we present a biodiversity "dashboard"--a visualization of biodiversity indicators designed to enable tracking of biodiversity and conservation performance data in a clear, user-friendly format. This builds on previous, more conceptual, indicator work to create an operationalized online interface communicating multiple indicators at multiple spatial scales. We structured this dashboard around the Pressure-State-Response-Benefit framework, selecting four indicators to measure pressure on biodiversity (deforestation rate), state of species (Red List Index), conservation response (protection of key biodiversity areas), and benefits to human populations (freshwater provision). Disaggregating global data, we present dashboard maps and graphics for the three regions surveyed and their component countries. These visualizations provide charts showing regional and national trends and lay the foundation for a web-enabled, interactive biodiversity indicators dashboard. This new tool can help track progress toward the Aichi Targets, support national monitoring and reporting, and inform outcome-based policy-making for the protection of

  18. Addressing the Global Sustainability Challenge: The Potential and Pitfalls of Private Governance from the Perspective of Human Capabilities

    NARCIS (Netherlands)

    Kalfagianni, A.

    2014-01-01

    Contemporary global politics is characterized by an increasing trend toward experimental forms of governance, with an emphasis on private governance. A plurality of private standards, codes of conduct and quality assurance schemes currently developed particularly, though not exclusively, by TNCs rep

  19. Addressing the Global Sustainability Challenge: The Potential and Pitfalls of Private Governance from the Perspective of Human Capabilities

    NARCIS (Netherlands)

    Kalfagianni, A.

    2014-01-01

    Contemporary global politics is characterized by an increasing trend toward experimental forms of governance, with an emphasis on private governance. A plurality of private standards, codes of conduct and quality assurance schemes currently developed particularly, though not exclusively, by TNCs rep

  20. Addressing capability computing challenges of high-resolution global climate modelling at the Oak Ridge Leadership Computing Facility

    Science.gov (United States)

    Anantharaj, Valentine; Norman, Matthew; Evans, Katherine; Taylor, Mark; Worley, Patrick; Hack, James; Mayer, Benjamin

    2014-05-01

    During 2013, high-resolution climate model simulations accounted for over 100 million "core hours" using Titan at the Oak Ridge Leadership Computing Facility (OLCF). The suite of climate modeling experiments, primarily using the Community Earth System Model (CESM) at nearly 0.25 degree horizontal resolution, generated over a petabyte of data and nearly 100,000 files, ranging in sizes from 20 MB to over 100 GB. Effective utilization of leadership class resources requires careful planning and preparation. The application software, such as CESM, need to be ported, optimized and benchmarked for the target platform in order to meet the computational readiness requirements. The model configuration needs to be "tuned and balanced" for the experiments. This can be a complicated and resource intensive process, especially for high-resolution configurations using complex physics. The volume of I/O also increases with resolution; and new strategies may be required to manage I/O especially for large checkpoint and restart files that may require more frequent output for resiliency. It is also essential to monitor the application performance during the course of the simulation exercises. Finally, the large volume of data needs to be analyzed to derive the scientific results; and appropriate data and information delivered to the stakeholders. Titan is currently the largest supercomputer available for open science. The computational resources, in terms of "titan core hours" are allocated primarily via the Innovative and Novel Computational Impact on Theory and Experiment (INCITE) and ASCR Leadership Computing Challenge (ALCC) programs, both sponsored by the U.S. Department of Energy (DOE) Office of Science. Titan is a Cray XK7 system, capable of a theoretical peak performance of over 27 PFlop/s, consists of 18,688 compute nodes, with a NVIDIA Kepler K20 GPU and a 16-core AMD Opteron CPU in every node, for a total of 299,008 Opteron cores and 18,688 GPUs offering a cumulative 560

  1. The Global Energy Challenge

    DEFF Research Database (Denmark)

    Connolly, David

    2011-01-01

    This report gives a brief overview of the global energy challenge and subsequently outlines how and where renewable energy could be developed to solve these issues. The report does not go into a lot of detail on these issues and hence, it is meant as an overview only. The report begins by outlining...... the causes of global climate change, concluding that energy-related emissions are the primary contributors to the problem. As a result, global energy production is analysed in more detail, discussing how it has evolved over the last 30 years and also, how it is expected to evolve in the coming 30 years....... Afterwards, the security of the world’s energy supply is investigated and it becomes clear that there is both an inevitable shortage of fossil fuels and a dangerous separation of supply and demand. The final topic discussed is renewable energy, since it is one sustainable solution to the global energy...

  2. Strategies for Addressing Spreadsheet Compliance Challenges

    CERN Document Server

    Weber, Brandon

    2006-01-01

    Most organizations today use spreadsheets in some form or another to support critical business processes. However the financial resources, and developmental rigor dedicated to them are often minor in comparison to other enterprise technology. The increasing focus on achieving regulatory and other forms of compliance over key technology assets has made it clear that organizations must regard spreadsheets as an enterprise resource and account for them when developing an overall compliance strategy. This paper provides the reader with a set of practical strategies for addressing spreadsheet compliance from an organizational perspective. It then presents capabilities offered in the 2007 Microsoft Office System which can be used to help customers address compliance challenges.

  3. HEP technologies to address medical imaging challenges

    CERN Document Server

    CERN. Geneva

    2016-01-01

    Developments in detector technologies aimed at solving challenges in present and future CERN experiments, particularly at the LHC, have triggered exceptional advances in the performance of medical imaging devices, allowing for a spectacular progress in in-vivo molecular imaging procedures, which are opening the way for tailored therapies of major diseases. This talk will briefly review the recent history of this prime example of technology transfer from HEP experiments to society, will describe the technical challenges being addressed by some ongoing projects, and will present a few new ideas for further developments and their foreseeable impact.

  4. Meeting global conservation challenges

    Science.gov (United States)

    2016-10-01

    Hot on the heels of last year's Sustainable Development Goals and the Paris Agreement, representatives from the global conservation community met to set the conservation agenda that will help to implement these targets.

  5. Addressing South Africa’s urban challenges

    Directory of Open Access Journals (Sweden)

    Jayne M. Rogerson

    2014-07-01

    Full Text Available South Africa is among the most urbanized countries in Africa and has an urban population that is growing rapidly. The country’s urban challenges sometimes are considered as distinctive and separate to those of rest of Africa because of the apartheid legacy of a fragmented and racially splintered urban landscape. Nevertheless, 20 years after democratic transition the issues that confront its cities increasingly exhibit a set of sustainability challenges that typify those problems of many other fast-growing African urban areas. This introduction locates the collection of articles as a contribution to the expanding corpus of scholarship on urban South Africa.

  6. Addressing climate challenges in developing countries

    Science.gov (United States)

    Tilmes, Simone; Monaghan, Andrew; Done, James

    2012-04-01

    Advanced Study Program/Early Career Scientist Assembly Workshop on Regional Climate Issues in Developing Countries; Boulder, Colorado, 19-22 October 2011 The Early Career Scientist Assembly (ECSA) and the Advanced Study Program of the National Center for Atmospheric Research (NCAR) invited 35 early-career scientists from nearly 20 countries to attend a 3-day workshop at the NCAR Mesa Laboratory prior to the World Climate Research Programme (WCRP) Open Science Conference in October 2011. The goal of the workshop was to examine a range of regional climate challenges in developing countries. Topics included regional climate modeling, climate impacts, water resources, and air quality. The workshop fostered new ideas and collaborations between early-career scientists from around the world. The discussions underscored the importance of establishing partnerships with scientists located in typically underrepresented countries to understand and account for the local political, economic, and cultural factors on which climate change is superimposed.

  7. Partnerships as panacea for addressing global problems?

    NARCIS (Netherlands)

    A. Kolk (Ans)

    2013-01-01

    textabstractThis chapter examines partnerships and their peculiarities, based on recent research from various disciplines, in the context of the large problems faced by (global) society. These problems are very complex, often cross national boundaries, and cannot easily be 'solved' by one single act

  8. Partnerships as panacea for addressing global problems?

    NARCIS (Netherlands)

    A. Kolk (Ans)

    2013-01-01

    textabstractThis chapter examines partnerships and their peculiarities, based on recent research from various disciplines, in the context of the large problems faced by (global) society. These problems are very complex, often cross national boundaries, and cannot easily be 'solved' by one single

  9. ADDRESSING THE RISKS OF GLOBAL PRODUCT DEVELOPMENT

    DEFF Research Database (Denmark)

    Hansen, Zaza Nadja Lee; Ahmed-Kristensen, Saeema

    2011-01-01

    Offshoring various stages in the product development process – from engineering tasks like R&D and design to manufacturing activities - can impact the development process, the product and the organisation. Some of these impacts are positive while some are negative. The negative impacts are related...... to rework, misunderstandings, miscommunication and lower quality. This paper investigates how the organisation can reduce the negative aspects of offshoring by presenting two possible approaches; one which lessens the exposure to situations in which these negative impacts happen and another which addresses...

  10. Global Challenges and Local Responses

    DEFF Research Database (Denmark)

    Wad, Peter

    2005-01-01

    The paper aims to address the question whether the dynamic of autoworker unionism in South Korea and Malaysia was conditioned by, and eventually also influenced the globalization processes in the local auto industry? The conclusion is a contextualized "yes", and the core argument is the following......: The financial crisis in 1997 was the dramatic peak of financial globalization in East Asia in the 1990s, and it did accelerate the existing trend in Korea towards centralized unionism in the auto industry, while it suspended the trend in the Malaysian auto industry towards decentralized unionism. Although...... and militant and a more pragmatic and moderate strategy. In the global-local perspective we face two paradoxes. The first paradox is that in spite of the difference in union ideology, the outcome in terms of industrial relations (IR) institutions was rather similar in the sense that the auto industry contained...

  11. Four Challenges That Global Health Networks Face

    Directory of Open Access Journals (Sweden)

    Jeremy Shiffman

    2017-04-01

    Full Text Available Global health networks, webs of individuals and organizations with a shared concern for a particular condition, have proliferated over the past quarter century. They differ in their effectiveness, a factor that may help explain why resource allocations vary across health conditions and do not correspond closely with disease burden. Drawing on findings from recently concluded studies of eight global health networks—addressing alcohol harm, early childhood development (ECD, maternal mortality, neonatal mortality, pneumonia, surgically-treatable conditions, tobacco use, and tuberculosis—I identify four challenges that networks face in generating attention and resources for the conditions that concern them. The first is problem definition: generating consensus on what the problem is and how it should be addressed. The second is positioning: portraying the issue in ways that inspire external audiences to act. The third is coalition-building: forging alliances with these external actors, particularly ones outside the health sector. The fourth is governance: establishing institutions to facilitate collective action. Research indicates that global health networks that effectively tackle these challenges are more likely to garner support to address the conditions that concern them. In addition to the effectiveness of networks, I also consider their legitimacy, identifying reasons both to affirm and to question their right to exert power.

  12. Online Learning: Addressing Challenges and Seizing Opportunities. Kansas

    Science.gov (United States)

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  13. Online Learning: Addressing Challenges and Seizing Opportunities. Hawaii

    Science.gov (United States)

    Alliance for Excellent Education, 2010

    2010-01-01

    America's K-12 education system faces three significant challenges: (1) increased global demands for skilled workers, (2) significant financial shortfalls, and (3) a looming teacher shortage. Independently, these factors present significant challenges for U.S. schools. In combination, they create a national imperative for swift action to create a…

  14. Biodiversity data provision and decision-making - addressing the challenges

    Directory of Open Access Journals (Sweden)

    Katherine Despot-Belmonte

    2017-02-01

    Full Text Available Essential Biodiversity Variables (EBVs are measurements required for study, reporting, and management of biodiversity change. They are being developed to support consistency, from the collection to the reporting of biodiversity data at the national, regional and global scales. However, "EBV stakeholders" need to strike a balance between 'doing innovative research' and 'having positive impact' on biodiversity management decisions. This paper reports on a workshop entitled Identifying joint pathways to address the challenges of biodiversity data provision and decision-making and presents the main workshop’s output, a “researcher’s brief” entitled Guiding principles for promoting the application of EBVs for current and future needs of decision-makers. These guiding principles are: Speak with a common voice; Clearly define what is an EBV and how it relates to indicators; Engage beyond the research world; Be realistic about what can be done now and later; Define criteria for good EBVs; Use EBV as a clearing house; Convey the limitations of EBVs; Clarify what impact EBVs should have; Be salient, credible, legitimate, iterative; Don't put an EBV skin on everything you do; Don't create too many EBVs; and Don't reduce EBVs to building blocks of indicators. This brief is of relevance to the wider GEO BON (Group on Earth Observation Biodoversity Observation Network community, and in particular those scientists/researchers interested in the application of EBVs.

  15. Addressing Earth Science Data Access Challenges through User Experience Research

    Science.gov (United States)

    Hemmings, S. N.; Banks, B.; Kendall, J.; Lee, C. M.; Irwin, D.; Toll, D. L.; Searby, N. D.

    2013-12-01

    The NASA Capacity Building Program (Earth Science Division, Applied Sciences Program) works to enhance end-user capabilities to employ Earth observation and Earth science (EO/ES) data in decision-making. Open data access and user-tailored data delivery strategies are critical elements towards this end. User Experience (UX) and User Interface (UI) research methods can offer important contributions towards addressing data access challenges, particularly at the interface of science application/product development and product transition to end-users. This presentation focuses on developing nation contexts and describes methods, results, and lessons learned from two recent UX/UI efforts conducted in collaboration with NASA: the SERVIRglobal.net redesign project and the U.S. Water Partnership (USWP) Portal development effort. SERVIR, a collaborative venture among NASA, USAID, and global partners, seeks to improve environmental management and climate change response by helping governments and other stakeholders integrate EO and geospatial technologies into decision-making. The USWP, a collaboration among U.S. public and private sectors, harnesses U.S.-based resources and expertise to address water challenges in developing nations. SERVIR's study, conducted from 2010-2012, assessed and tested user needs, preferences, and online experiences to generate a more user-friendly online data portal at SERVIRglobal.net. The portal provides a central access interface to data and products from SERVIR's network of hubs in East Africa, the Hindu Kush Himalayas, and Mesoamerica. The second study, conducted by the USWP Secretariat and funded by the U.S. Department of State, seeks to match U.S.-based water information resources with developing nation stakeholder needs. The USWP study utilizes a multi-pronged approach to identify key design requirements and to understand the existing water data portal landscape. Adopting UX methods allows data distributors to design customized UIs that

  16. Catholic Social Teaching: Addressing Globalization in Catholic Business Education

    Science.gov (United States)

    Ball, James B.; Martinez, Zaida; Toyne, Brian

    2009-01-01

    Although business schools are increasingly aware of the importance of globalization in educating future business leaders, their business programs have addressed globalization from a limited perspective that fails to provide students with a broader understanding of its impact on societies and its moral consequences. The conventional approach to the…

  17. Addressing Future Technology Challenges Through Innovation and Investment

    Science.gov (United States)

    2012-03-01

    thank my loving wife and children for their undying support during my fellowship and career to this point.   1   Chapter 1   Addressing...Future Technology Challenges: Innovate or Die!   I thoroughly disapprove of duels . If a man should challenge me, I would take him kindly and...forgivingly by the hand and lead him to a quiet place and kill him. - Mark Twain Duels are foolish. Mark Twain’s approach to conflict resolution is

  18. Globalization challenges in a globalized world

    Directory of Open Access Journals (Sweden)

    Dr.Sc. Gjon Boriçi

    2016-01-01

    Full Text Available Globalization is an ongoing phenomenon trying to redefine the economic, social, cultural and political dynamics of contemporary societies. The communication among countries and not only them, has been increased expanding political ties, making possible greater economic integration and wider cultural relations combined with augmented global wealth across the world. But, the process of globalization is in wider terms considered a beneficial one, but also viewed by some countries as a menace to national sovereignty and national culture. This paper tries to explain the obstacles to the process of globalization and its attendant benefits. Although globalization has arisen as a result of a more stable world, the factors that had contributed to its rise also help the factions interested to bring destabilization. In an academic approach in this article, between the research and comparative methods, I have been trying to get the maxims between economy, politics and diplomacy in their efforts of affecting the global era.

  19. International migration: a global challenge.

    Science.gov (United States)

    Martin, P; Widgren, J

    1996-04-01

    Trends in international migration are presented in this multiregional analysis. Seven of the world's wealthiest countries have about 33% of the world's migrant population, but under 16% of the total world population. Population growth in these countries is substantially affected by the migrant population. The migration challenge is external and internal. The external challenge is to balance the need for foreign labor and the commitment to human rights for those migrants seeking economic opportunity and political freedom. The internal challenge is to assure the social adjustment of immigrants and their children and to integrate them into society as citizens and future leaders. Why people cross national borders and how migration flows are likely to evolve over the next decades are explained. This report also presents some ways that countries can manage migration or reduce the pressures which force people to migrate. It is recommended that receiving nations control immigration by accelerating global economic growth and reducing wars and human rights violations. This report examines the impact of immigration on international trade, aid, and direct intervention policies. Although migration is one of the most important international economic issues, it is not coordinated by an international group. The European experience indicates that it is not easy to secure international cooperation on issues that affect national sovereignty. It is suggested that countries desiring control of their borders should remember that most people never cross national borders to live or work in another country, that 50% of the world's migrants move among developing countries, and that countries can shift from being emigration to immigration countries. The author suggests that sustained reductions in migration pressure are a better alternative than the "quick fixes" that may invite the very much feared mass and unpredictable movements.

  20. Challenges to using a business case for addressing health disparities.

    Science.gov (United States)

    Lurie, Nicole; Somers, Stephen A; Fremont, Allen; Angeles, January; Murphy, Erin K; Hamblin, Allison

    2008-01-01

    The authors consider the challenges to quantifying both the business case and the social case for addressing disparities, which is central to achieving equity in the U.S. health care system. They describe the practical and methodological challenges faced by health plans exploring the business and social cases for undertaking disparity-reducing interventions. Despite these challenges, sound business and quality improvement principles can guide health care organizations seeking to reduce disparities. Place-based interventions may help focus resources and engage health care and community partners who can share in the costs of-and gains from-such efforts.

  1. The global business of chemistry:prospects and challenges

    OpenAIRE

    Swift, T.K. (Thomas)

    2006-01-01

    The global business of chemistry has faced numerous challenges in recent years. This article addresses the near-term business environment in which the industry will operate as well as the implications for the global business of chemistry during 2006 and 2007.

  2. Addressing strategy execution challenges to lead sustainable change.

    Science.gov (United States)

    Shirey, Maria R

    2011-01-01

    This department highlights change management strategies that may be successful in strategically planning and executing organizational change initiatives. With the goal of presenting practical approaches helpful to nurse leaders advancing organizational change, content includes evidence-based projects, tools, and resources that mobilize and sustain organizational change initiatives. In this article, the author discusses strategy execution challenges that must be addressed to lead sustainable change.

  3. Knowledge Management Challenges For Global Business

    OpenAIRE

    Veli Denizhan Kalkan

    2011-01-01

    Managing organizational knowledge effectively is a prerequisite for securing competitive advantages in the global marketplace. The field of knowledge management brings out important challenges for global business practices. Based on a comprehensive academic and popular literature review, this paper identifies six main knowledge management challenges faced by global business today. These are developing a working definition of knowledge, dealing with tacit knowledge and utilization of informati...

  4. Challenges in Diabetes Care: Can Digital Health Help Address Them?

    Science.gov (United States)

    Iyengar, Varun; Wolf, Alexander; Brown, Adam; Close, Kelly

    2016-07-01

    In Brief There is great enthusiasm for the potential of digital health solutions in medicine and diabetes to address key care challenges: patient and provider burden, lack of data to inform therapeutic decision-making, poor access to care, and costs. However, the field is still in its nascent days; many patients and providers do not currently engage with digital health tools, and for those who do, the burden is still often high. Over time, digital health has excellent potential to collect data more seamlessly, make collected data more useful, and drive better outcomes at lower costs in less time. But there is still much to prove. This review offers key background information on the current state of digital health in diabetes, six of the most promising digital health technologies and services, and the challenges that remain.

  5. Jointly addressing the challenge: Developing a sustainable energy system

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ An energy report entitled Lighting the Way. Toward a Sustainable Energy Future by the InterAcademy Council (IAC), and the other one entitled Addressing the Challenge: Developing a Sustainable Energy System by CAS, were jointly released recently. The Sustainable Energy Forum: Panel Discussions on IAC/CAS Energy Reports, organized by CAS and held in Beijing on the afternoon of 22 October 2007, attracted around 50 distinguished participants, including senior governmental leaders, experts, and industrial representatives from both domestic and foreign energyrelated organizations.

  6. Field-flow fractionation: addressing the nano challenge.

    Science.gov (United States)

    Williams, S Kim Ratanathanawongs; Runyon, J Ray; Ashames, Akram A

    2011-02-01

    Field-flow fractionation is coming of age as a family of analytical methods for separating and characterizing macromolecules, nanoparticles, and particulates. The capabilities and versatility of these techniques are discussed in light of the challenges that are being addressed in analyzing nanometer-sized sample components and the insights gained through their use in applications ranging from materials science to biology. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .).

  7. GASP: A Performance Analysis Tool Interface for Global AddressSpace Programming Models, Version 1.5

    Energy Technology Data Exchange (ETDEWEB)

    Leko, Adam; Bonachea, Dan; Su, Hung-Hsun; George, Alan D.; Sherburne, Hans; George, Alan D.

    2006-09-14

    Due to the wide range of compilers and the lack of astandardized performance tool interface, writers of performance toolsface many challenges when incorporating support for global address space(GAS) programming models such as Unified Parallel C (UPC), Titanium, andCo-Array Fortran (CAF). This document presents a Global Address SpacePerformance tool interface (GASP) that is flexible enough to be adaptedinto current global address space compiler and runtime infrastructureswith little effort, while allowing performance analysis tools to gathermuch information about the performance of global address spaceprograms.

  8. Global neurotrauma research challenges and opportunities.

    Science.gov (United States)

    Rubiano, Andrés M; Carney, Nancy; Chesnut, Randall; Puyana, Juan Carlos

    2015-11-19

    Traumatic injury to the brain or spinal cord is one of the most serious public health problems worldwide. The devastating impact of 'trauma', a term used to define the global burden of disease related to all injuries, is the leading cause of loss of human potential across the globe, especially in low- and middle-income countries. Enormous challenges must be met to significantly advance neurotrauma research around the world, specifically in underserved and austere environments. Neurotrauma research at the global level needs to be contextualized: different regions have their own needs and obstacles. Interventions that are not considered a priority in some regions could be a priority for others. The introduction of inexpensive and innovative interventions, including mobile technologies and e-health applications, focused on policy management improvement are essential and should be applicable to the needs of the local environment. The simple transfer of a clinical question from resource-rich environments to those of low- and middle-income countries that lack sophisticated interventions may not be the best strategy to address these countries' needs. Emphasis on promoting the design of true 'ecological' studies that include the evaluation of human factors in relation to the process of care, analytical descriptions of health systems, and how leadership is best applied in medical communities and society as a whole will become crucial.

  9. Global change and the groundwater management challenge

    Science.gov (United States)

    Gorelick, Steven M.; Zheng, Chunmiao

    2015-05-01

    With rivers in critical regions already exploited to capacity throughout the world and groundwater overdraft as well as large-scale contamination occurring in many areas, we have entered an era in which multiple simultaneous stresses will drive water management. Increasingly, groundwater resources are taking a more prominent role in providing freshwater supplies. We discuss the competing fresh groundwater needs for human consumption, food production, energy, and the environment, as well as physical hazards, and conflicts due to transboundary overexploitation. During the past 50 years, groundwater management modeling has focused on combining simulation with optimization methods to inspect important problems ranging from contaminant remediation to agricultural irrigation management. The compound challenges now faced by water planners require a new generation of aquifer management models that address the broad impacts of global change on aquifer storage and depletion trajectory management, land subsidence, groundwater-dependent ecosystems, seawater intrusion, anthropogenic and geogenic contamination, supply vulnerability, and long-term sustainability. The scope of research efforts is only beginning to address complex interactions using multiagent system models that are not readily formulated as optimization problems and that consider a suite of human behavioral responses.

  10. IAB presidential address: bioethics in a globalized world: creating space for flourishing human relationships.

    Science.gov (United States)

    Biller-Andorno, Nikola

    2011-10-01

    Bioethics in a globalized world is meeting a number of challenges - fundamentalism in its different forms, and a focus on economic growth neglecting issues such as equity and sustainability, being prominent among them. How well are we as bioethicists equipped to make meaningful contributions in these times? The paper identifies a number of restraints and proceeds to probe potential resources such as the capability approach, care ethics, cosmopolitanism, and pragmatism. These elements serve to outline a perspective that focuses on the preconditions for flourishing human relationships as a way to address bioethical challenges in a globalized world.

  11. Pediatric Sedation: A Global Challenge

    Directory of Open Access Journals (Sweden)

    David Gozal

    2010-01-01

    Full Text Available Pediatric sedation is a challenge which spans all continents and has grown to encompass specialties outside of anesthesia, radiology and emergency medicine. All sedatives are not universally available and local and national regulations often limit the sedation practice to specific agents and those with specific credentials. Some specialties have established certification and credentials for sedation delivery whereas most have not. Some of the relevant sedation guidelines and recommendations of specialty organizations worldwide will be explored. The challenge facing sedation care providers moving forward in the 21st century will be to determine how to apply the local, regional and national guidelines to the individual sedation practices. A greater challenge, perhaps impossible, will be to determine whether the sedation community can come together worldwide to develop standards, guidelines and recommendations for safe sedation practice.

  12. CULTURAL DIVERSITY: A GLOBAL CHALLENGE

    Directory of Open Access Journals (Sweden)

    Irina LECA

    2015-06-01

    Full Text Available XXI century is the century of globalization, a century dominated by multinational organizations supremacy which gradually expanded to conquer the world through their products and services. In every industry working professionals need to interact with people from other ethnic and nationals groups, at home, job and around the world. Decisively all meant for companies and organizations, in addition to innovation and development the source of possible conflicts. Therefore what does cultural diversity mean and how it should be managed?

  13. GLOBALIZATION AND THE NEW ENERGY CHALLENGES

    Directory of Open Access Journals (Sweden)

    Preda (AndreescuMihaela

    2008-05-01

    Full Text Available A New Global Energy Economy is emerging, in which energy demand and supply issues will make regions of the world much more dependent upon each other. International extensive energetic interdependence on energy resources and networks grows in the global economy. Some $22 trillion of investment in supply infrastructure is needed to meet projected global demand until 2030. Mobilising all this investment will be challenging. Adherence to these policies will ensure that the global energy investments materializes, the necessary infrastructure is built, and the lengthening worldwide energy supply chain operates in security. Strong global energy policy is needed to move the world into a more sustainable energy path.

  14. ISLAM: Local and Global Challenges

    Directory of Open Access Journals (Sweden)

    Editor Al-Jami'ah: Journal of Islamic Studies

    2011-02-01

    Full Text Available Indeed, in maintaining their local values when faced with globalchallenges, Muslims, as a social entity, and Islam, as a set of dogma, havegiven birth to new phenomena, e.g. new interpretation of Islam withina new context. Additionally, this era of globalization has led religions,including Islam, to renew their gambit to cope reality, e.g. in the practicallife (sociological, political, economical and anthropological aspects,intellectual endeavors (philosophical and theological aspects, and in therenewal of dogmatic teachings (hermeneutical aspects.

  15. Globalization and Its Challenges for Teacher Education

    Science.gov (United States)

    Wang, Jian; Odell, Sandra J.

    2008-01-01

    There are serious implications of the global economy for teacher education. In this paper, the authors identify some of the influences of the global economy on education and teacher education, point out responses to these, and discuss some of the resultant challenges from the vantage point of the United States.

  16. Globalization and Its Challenges for Teacher Education

    Science.gov (United States)

    Wang, Jian; Odell, Sandra J.

    2008-01-01

    There are serious implications of the global economy for teacher education. In this paper, the authors identify some of the influences of the global economy on education and teacher education, point out responses to these, and discuss some of the resultant challenges from the vantage point of the United States.

  17. Evaluating complex community-based health promotion: addressing the challenges.

    Science.gov (United States)

    Jolley, Gwyneth

    2014-08-01

    Community-based health promotion is poorly theorised and lacks an agreed evidence-base. This paper examines characteristics of community-based health promotion and the challenges they present to evaluation. A review of health promotion evaluation leads to an exploration of more recent approaches, drawing on ideas from complexity theory and developmental evaluation. A reflexive analysis of three program evaluations previously undertaken as an evaluation consultant is used to develop a conceptual model to help in the design and conduct of health promotion evaluation. The model is further explored by applying it retrospectively to one evaluation. Findings suggest that the context-contingent nature of health promotion programs; turbulence in the community context and players; multiple stakeholders, goals and strategies; and uncertainty of outcomes all contribute to the complexity of interventions. Bringing together insights from developmental evaluation and complexity theory can help to address some evaluation challenges. The proposed model emphasises recognising and responding to changing contexts and emerging outcomes, providing rapid feedback and facilitating reflexive practice. This will enable the evaluator to gain a better understanding of the influence of context and other implementation factors in a complex setting. Use of the model should contribute to building cumulative evidence and knowledge in order to identify the principles of health promotion effectiveness that may be transferable to new situations.

  18. Problems of global warming and role of micropaleontologists - Presidential Address

    Digital Repository Service at National Institute of Oceanography (India)

    Nigam, R.

    stream_size 10784 stream_content_type text/plain stream_name Gondwana_Geol_Mag_6_1.pdf.txt stream_source_info Gondwana_Geol_Mag_6_1.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 Problems... of Global Warming and Role of Micropaleontologists Rajiv Nigam National Institute of Oceanography, Dona Paula, Goa - 403004 Email : rajeev@darya.nio.org. One of the most challenging problems faced by the mankind today, is the constantly increasing mean...

  19. Women and Smoking: Global Challenge

    Directory of Open Access Journals (Sweden)

    Taru Kinnunen

    2016-03-01

    Full Text Available Global tobacco control has led to a reduction in smoking prevalence and mortality in men, while the rates among women have not followed the same declining rates or patterns. Tobacco-induced diseases, including those unique to women (reproductive complications, cervical and breast cancer are becoming increasingly prevalent among women. Unfortunately, many tobacco control policies and cessation programs have been found to be less effective for women than men. This is alarming as disease risk for lung cancer, CVD, osteoporosis, and COPD, associated with smoking, is higher among women. Women are also more likely to be exposed to secondhand tobacco smoke and subsequent morbidity. Finally, quitting smoking appears to be harder for women than men. Current tobacco control and surveillance data come primarily from high resource countries. WHO estimates that in 2030, in low and medium resource countries, 7 out of 10 deaths will be smoking-related. While the prevalence of smoking in women is relatively low in these countries, more information is needed regarding their patterns of tobacco use uptake, and subsequent health outcomes, as theirs differ from men. Tobacco use in women is greatly influenced by social, cultural and political determinants, and needs to be conceptualized within an intersectional framework.

  20. Is prophetic discourse adequate to address global economic justice?

    Directory of Open Access Journals (Sweden)

    Piet J. Naudé

    2011-06-01

    Full Text Available This article outlined key features of prophetic discourse and investigated whether this form of moral discourse adequately addresses issues of economic injustice. It is shown that the strength of prophetic discourse is its ability to denounce instances of injustice whilst at the same time announcing a God-willed alternative future. The ‘preferential option for the poor’ in Latin American liberation theologies is treated as a case study of the influence of prophetic discourse in contexts of perceived economic injustice. Also the core weaknesses of prophetic discourse are investigated, specifically its incomplete moral argument, weak moral analyses, silence on transition measures, and its inability to take a positive stance on reforms in the system from which itself benefits. In the final section it is concluded that prophetic discourse plays an indispensable role in addressing issues of global economic justice, but – taken by itself – it is not an adequate form of moral discourse to address concrete matters of justice.

  1. Addressing psychiatric education in Latin America: challenges and opportunities.

    Science.gov (United States)

    Fahrer, Rodolfo; Jorge, Miguel R; Ruiz, Pedro

    2010-01-01

    This article is about the psychiatric educational components in the field of psychiatry. Currently the training and educational objectives focus on five major areas: undergraduate education (medical students); graduate education (psychiatric residents); psychiatric education for primary care physicians, as well as physicians in other medical specializations (psychosomatic training); public health and public education at large, and patient and family education, and the promotion of 'mental health' at a community level. Given the strong globalization process observed in all regions of the world in the past two or three decades, it is very important for Latin America to constantly review and update its psychiatric and behavioural sciences curriculum across all medical institutions and universities of the continent. New methods of teaching and novel approaches to education in the field of psychiatry are currently based on models that are also in use in other parts of the world, especially in the USA. Boards of certification for psychiatrists are being implemented all over the continent. Sound certification guarantees that the professional has followed and passed an educational training plan to make him/her qualified to start practising the profession. The future of psychiatric training will be closely bound to the future of the practice of psychiatry, and will have to get ahead of the challenges the specialism will face during the next decades.

  2. How does Software Process Improvement Address Global Software Engineering?

    DEFF Research Database (Denmark)

    Kuhrmann, Marco; Diebold, Philipp; Münch, Jürgen

    2016-01-01

    a systematic mapping study on the state-of-the-art in SPI from a general perspective, we observed Global Software Engineering (GSE) becoming a topic of interest in recent years. Therefore, in this paper, we provide a detailed investigation of those papers from the overall systematic mapping study that were......For decades, Software Process Improvement (SPI) programs have been implemented, inter alia, to improve quality and speed of software development. To set up, guide, and carry out SPI projects, and to measure SPI state, impact, and success, a multitude of different SPI approaches and considerable...... experience are available. SPI addresses many aspects ranging from individual developer skills to entire organizations. It comprises for instance the optimization of specific activities in the software lifecycle as well as the creation of organization awareness and project culture. In the course of conducting...

  3. Towards a feminist global bioethics: addressing women's health concerns worldwide.

    Science.gov (United States)

    Tong, R

    2001-01-01

    In this paper I argue that a global bioethics is possible. Specifically, I present the view that there are within feminist approaches to bioethics some conceptual and methodological tools necessary to forge a bioethics that embraces the health-related concerns of both developing and developed nations equally. To support my argument I discuss some of the challenges that have historically confronted feminists. If feminists accept the idea that women are entirely the same, then feminists present as fact the fiction of the essential "Woman." Not only does "Woman" not exist, -she" obscures important racial, ethnic, cultural, and class differences among women. However, if feminists stress women's differences too much, feminists lose the power to speak coherently and cogently about gender justice, women's rights, and sexual equality in general. Analyzing the ways in which the idea of difference as well as the idea of sameness have led feminists astray, I ask whether it is possible to avoid the Scylla of absolutism (imperialism, colonialism, hegemony) on the one hand and the Charybdis of relativism (postmodernism, fragmentation, Balkanization) on the other. Finally, after reflecting upon the work of Uma Narayan, Susan Muller Okin, and Martha Nussbaum, I conclude that there is a way out of this ethical bind. By focusing on women's, children's, and men's common human needs, it is possible to lay the foundation for a just and caring global bioethics.

  4. Data monitoring committees: Promoting best practices to address emerging challenges.

    Science.gov (United States)

    Fleming, Thomas R; DeMets, David L; Roe, Matthew T; Wittes, Janet; Calis, Karim A; Vora, Amit N; Meisel, Alan; Bain, Raymond P; Konstam, Marvin A; Pencina, Michael J; Gordon, David J; Mahaffey, Kenneth W; Hennekens, Charles H; Neaton, James D; Pearson, Gail D; Andersson, Tomas Lg; Pfeffer, Marc A; Ellenberg, Susan S

    2017-04-01

    Data monitoring committees are responsible for safeguarding the interests of study participants and assuring the integrity and credibility of clinical trials. The independence of data monitoring committees from sponsors and investigators is essential in achieving this mission. Creative approaches are needed to address ongoing and emerging challenges that potentially threaten data monitoring committees' independence and effectiveness. An expert panel of representatives from academia, industry and government sponsors, and regulatory agencies discussed these challenges and proposed best practices and operating principles for effective functioning of contemporary data monitoring committees. Prospective data monitoring committee members need better training. Options could include didactic instruction as well as apprenticeships to provide real-world experience. Data monitoring committee members should be protected against legal liability arising from their service. While avoiding breaches in confidentiality of interim data remains a high priority, data monitoring committees should have access to unblinded efficacy and safety data throughout the trial to enable informed judgments about risks and benefits. Because overly rigid procedures can compromise their independence, data monitoring committees should have the flexibility necessary to best fulfill their responsibilities. Data monitoring committee charters should articulate principles that guide the data monitoring committee process rather than list a rigid set of requirements. Data monitoring committees should develop their recommendations by consensus rather than through voting processes. The format for the meetings of the data monitoring committee should maintain the committee's independence and clearly establish the leadership of the data monitoring committee chair. The independent statistical group at the Statistical Data Analysis Center should have sufficient depth of knowledge about the study at hand and

  5. Framing global health: the governance challenge.

    Science.gov (United States)

    McInnes, Colin; Kamradt-Scott, Adam; Lee, Kelley; Reubi, David; Roemer-Mahler, Anne; Rushton, Simon; Williams, Owain David; Woodling, Marie

    2012-01-01

    With the emergence of global health comes governance challenges which are equally global in nature. This article identifies some of the initial limitations in analyses of global health governance (GHG) before discussing the focus of this special supplement: the framing of global health issues and the manner in which this impacts upon GHG. Whilst not denying the importance of material factors (such as resources and institutional competencies), the article identifies how issues can be framed in different ways, thereby creating particular pathways of response which in turn affect the potential for and nature of GHG. It also identifies and discusses the key frames operating in global health: evidence-based medicine, human rights, security, economics and development.

  6. Addressing the Challenges of Distributed Hydrologic Modeling for Operational Forecasting

    Science.gov (United States)

    Butts, M. B.; Yamagata, K.; Kobor, J.; Fontenot, E.

    2008-05-01

    Operational forecasting systems must provide reliable, accurate and timely flood forecasts for a range of catchments from small rapidly responding mountain catchments and urban areas to large, complex but more slowly responding fluvial systems. Flood forecasting systems have evolved from simple forecasting for flood mitigation to real-time decision support systems for real-time reservoir operations for water supply, navigation, hydropower, for managing environmental flows and habitat protection, cooling water and water quality forecasting. These different requirements lead to a number of challenges in applying distributed modelling in an operational context. These challenges include, the often short time available for forecasting that requires a trade-off between model complexity and accuracy on the one hand and on the other hand the need for efficient calculations to reduce the computation times. Limitations in the data available in real-time require modelling tools that can not only operate on a minimum of data but also take advantage of new data sources such as weather radar, satellite remote sensing, wireless sensors etc. Finally, models must not only accurately predict flood peaks but also forecast low flows and surface water-groundwater interactions, water quality, water temperature, optimal reservoir levels, and inundated areas. This paper shows how these challenges are being addressed in a number of case studies. The central strategy has been to develop a flexible modelling framework that can be adapted to different data sources, different levels of complexity and spatial distribution and different modelling objectives. The resulting framework allows amongst other things, optimal use of grid-based precipitation fields from weather radar and numerical weather models, direct integration of satellite remote sensing, a unique capability to treat a range of new forecasting problems such as flooding conditioned by surface water-groundwater interactions. Results

  7. The Challenges and Potential of Nuclear Energy for Addressing Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Son H.; Edmonds, James A.

    2007-10-24

    The response to climate change and the stabilization of atmospheric greenhouse gas concentrations has major implications for the global energy system. Stabilization of atmospheric carbon dioxide (CO2) concentrations requires a peak and an indefinite decline of global CO2 emissions. Nuclear energy, along with other technologies, has the potential to contribute to the growing demand for energy without emitting CO2. Nuclear energy is of particular interest because of its global prevalence and its current significant contribution, nearly 20%, to the world’s electricity supply. We have investigated the value of nuclear energy in addressing climate change, and have explored the potential challenges for the rapid and large-scale expansion of nuclear energy as a response to climate change. The scope of this study is long-term and the modeling time frame extends out a century because the nature of nuclear energy and climate change dictate that perspective. Our results indicate that the value of the nuclear technology option for addressing climate change is denominated in trillions of dollars. Several-fold increases to the value of the nuclear option can be expected if there is limited availability of competing carbon-free technologies, particularly fossil-fuel based technologies that can capture and sequester carbon. Challenges for the expanded global use of nuclear energy include the global capacity for nuclear construction, proliferation, uranium availability, and waste disposal. While the economic costs of nuclear fuel and power are important, non-economic issues transcend the issues of costs. In this regard, advanced nuclear technologies and new vision for the global use of nuclear energy are important considerations for the future of nuclear power and climate change.

  8. Ethical Challenges Regarding Globalization of Higher Education

    Science.gov (United States)

    Olivier, Bert

    2011-01-01

    This paper places the question of ethical challenges in relation to the process of globalization concerning international education and the mobility of international students worldwide. It focuses on five areas of justice, namely, social and political justice, administrative justice, distributive justice, cultural justice and ecological justice.…

  9. The Global Challenge: A Matter of Balance.

    Science.gov (United States)

    Mulford, Bill

    2002-01-01

    Argues that global challenge created by the pressure for change requires educators to understand the balance between continuity and constant change dependence and independence, individualism and community, homogeneity and heterogeneity. To achieve balanced learning and development, education should place greater emphasis on continuity,…

  10. The global conduct of cancer clinical trials: challenges and opportunities.

    Science.gov (United States)

    Barrios, Carlos H; Werutsky, Gustavo; Martinez-Mesa, Jeovany

    2015-01-01

    The nature of clinical research has changed substantially over the last 2 decades, evolving from being centered almost exclusively in developed countries to a more global scenario that is increasingly involving less developed regions of the world. Pharmaceutical companies and some academic cooperative groups have been conducting challenging, large pivotal registration studies with multinational participation. The much more needed globalization of academic research demands particular attention and represents a worthwhile subject for a more profound discussion. The requirement of large sample sizes and the potential for fast recruitment leading to a speedy completion of clinical studies are probably the most important factors that have fueled globalization of studies. Reduced operational costs and the ability to expedite the regulatory approval of drugs in various countries or regions are also important drivers. Globalization of research should be seen as having a much wider effect in the societies involved, in particular, when we consider public health, economic, social, and ethical implications. Most importantly, the process of expanding the network of clinical research sites also fosters the integration and the development of closer relationships among investigators at a global level. We consider this an essential element that should remain a prominent element in the discussion. In this article, we address the underlying reasons for globalization and we highlight some of the scientific and ethical concerns arising as a consequence. Finally, some strategies to address and mitigate the challenges of conducting multinational clinical research are proposed.

  11. Addressing complex challenges using a co-innovation approach

    NARCIS (Netherlands)

    Vereijssen, Jessica; Srinivasan, M.S.; Dirks, Sarah; Fielke, Simon; Jongmans, C.T.; Agnew, Natasha; Klerkx, Laurens; Pinxterhuis, Ina; Moore, John; Edwards, Paul; Brazendale, Rob; Botha, Neels; Turner, James A.

    2017-01-01

    Co-innovation can be effective for complex challenges – involving interactions amongst multiple stakeholders, viewpoints, perceptions, practices and interests across programmes, sectors and national systems. Approaches to challenges in the primary sector have tended to be linear, where tools and

  12. Managing a scarce resource: addressing critical health workforce challenges.

    NARCIS (Netherlands)

    Giepmans. P.; Dussault, G.; Batenburg, R.; Frich, J.; Olivers, R.; Sermeus, W.

    2013-01-01

    With health care services significantly changing, the challenge is to initiate innovative, situational and integrated workforce forecasting and planning. Many health systems require a shift in mindset to move to the planning of skill mixes for health care professionals. This implies great challenges

  13. A Framework for Addressing Challenges to Classroom Technology Use

    Science.gov (United States)

    Groff, Jennifer; Mouza, Chrystalla

    2008-01-01

    Creating effective learning environments with technology remains a challenge for teachers. Despite the tremendous push for educators to integrate technology into their classrooms, many have yet to do so and struggle to find consistent success with technology-based instruction. The challenges to effective technology integration have been…

  14. Expanding the Role for Psychology in Addressing Environmental Challenges

    NARCIS (Netherlands)

    Clayton, Susan; Devine-Wright, Patrick; Swim, Janet; Bonnes, Mirilia; Steg, Linda; Whitmarsh, Lorraine; Carrico, Amanda

    2016-01-01

    Environmental challenges, though daunting, present an important area for psychologists to apply their knowledge. Psychological theories, research methods, and interventions are essential for examining the questions about human impacts, tendencies, and capacities that are integral to constructing eff

  15. A Canadian Effort to Address Fractions Teaching and Learning Challenges

    Science.gov (United States)

    Yearley, Shelley; Bruce, Catherine D.

    2014-01-01

    Teaching and learning fraction concepts provides challenges in primary schools all over the world. In this article, Shelley Yearley and Catherine Bruce describe a fractions-based research project conducted in Ontario, Canada.

  16. Global Challenges in the Domestic Appliances Industry

    OpenAIRE

    Dusan Gosnik

    2009-01-01

    The domestic appliances industry is a mature industry. Changes in the business environment such as political, law, cultural, social, ecological and technological influences have an effect on the future development of this industry. Challenges to producers in this industry are oriented towards the further globalisation of the business, managing processes, new product and innovations development, and towards establishing and empowerment of the product brands. Global trends in the use of some na...

  17. Teaching Digital Natives: Promoting Information Literacy and Addressing Instructional Challenges

    Science.gov (United States)

    Neumann, Crystal

    2016-01-01

    Technology must be used as a teaching and learning tool to help students succeed. However, educators must be proactive in identifying some of the pitfalls of technology, such as information illiteracy. The phenomenological study covers how English instructors from Indianapolis, who teach first year students, address information literacy and the…

  18. Teaching Digital Natives: Promoting Information Literacy and Addressing Instructional Challenges

    Science.gov (United States)

    Neumann, Crystal

    2016-01-01

    Technology must be used as a teaching and learning tool to help students succeed. However, educators must be proactive in identifying some of the pitfalls of technology, such as information illiteracy. The phenomenological study covers how English instructors from Indianapolis, who teach first year students, address information literacy and the…

  19. Addressing big data challenges for scientific data infrastructure

    NARCIS (Netherlands)

    Demchenko, Y.; Zhao, Z.; Grosso, P.; Wibisono, A.; de Laat, C.

    2012-01-01

    This paper discusses the challenges that are imposed by Big Data Science on the modern and future Scientific Data Infrastructure (SDI). The paper refers to different scientific communities to define requirements on data management, access control and security. The paper introduces the Scientific

  20. Preventing and Addressing Challenging Behavior: Common Questions and Practical Strategies

    Science.gov (United States)

    Hemmeter, Mary Louise; Ostrosky, Michaelene M.; Corso, Robert M.

    2012-01-01

    The purpose of this article is to offer preschool teachers strategies for preventing challenging behavior and supporting the development of social skills and emotional competencies. This article is framed in a question and answer format using questions from teachers who the authors have worked with in the past. These questions and strategies are…

  1. Addressing Challenging Behavior: Considering the Logic of Probability

    Science.gov (United States)

    Scott, Terrance M.; Hirn, Regina G.

    2014-01-01

    When dealing with children who exhibit challenging behaviors there are no known interventions that work for all students or at all times. Thus, intervention for these students is often implemented in a trial and error manner. This article provides a logic for considering probability as a factor in selecting strategies. Understanding that some…

  2. Addressing big data challenges for scientific data infrastructure

    NARCIS (Netherlands)

    Demchenko, Y.; Zhao, Z.; Grosso, P.; Wibisono, A.; de Laat, C.

    2012-01-01

    This paper discusses the challenges that are imposed by Big Data Science on the modern and future Scientific Data Infrastructure (SDI). The paper refers to different scientific communities to define requirements on data management, access control and security. The paper introduces the Scientific Dat

  3. Addressing Reticence: The Challenge of Engaging Reluctant Adult ESL Students

    Science.gov (United States)

    Carter, Steven J.; Henrichsen, Lynn E.

    2015-01-01

    Reticence frequently prevents adult ESL learners from learning as much as they otherwise might. The nature of second-language learning requires frequent performance that may challenge students' self-concepts, leading to reticence and self-consciousness. To reduce or prevent this problem, teachers must employ appropriate pedagogical and classroom…

  4. Science and Politics: Strategies to Address Global Warming

    OpenAIRE

    尹, 虎

    2013-01-01

    Global warming poses one of the most serious threats to the globalenvironment ever faced in human history. We have recognized the issue intime to do something about it, and we have methods and resources tomitigate global warming. Every decade we delay in taking action, we arecommitting the planet to additional warming that future generations have todeal with offer compelling evidence from a large body of information thatglobal climate change caused by global warming is already underway andreq...

  5. Science and Politics: Strategies to Address Global Warming

    OpenAIRE

    2013-01-01

    Global warming poses one of the most serious threats to the globalenvironment ever faced in human history. We have recognized the issue intime to do something about it, and we have methods and resources tomitigate global warming. Every decade we delay in taking action, we arecommitting the planet to additional warming that future generations have todeal with offer compelling evidence from a large body of information thatglobal climate change caused by global warming is already underway andreq...

  6. Balancing the benefits and risks of public-private partnerships to address the global double burden of malnutrition.

    Science.gov (United States)

    Kraak, Vivica I; Harrigan, Paige B; Lawrence, Mark; Harrison, Paul J; Jackson, Michaela A; Swinburn, Boyd

    2012-03-01

    Transnational food, beverage and restaurant companies, and their corporate foundations, may be potential collaborators to help address complex public health nutrition challenges. While UN system guidelines are available for private-sector engagement, non-governmental organizations (NGO) have limited guidelines to navigate diverse opportunities and challenges presented by partnering with these companies through public-private partnerships (PPP) to address the global double burden of malnutrition. We conducted a search of electronic databases, UN system websites and grey literature to identify resources about partnerships used to address the global double burden of malnutrition. A narrative summary provides a synthesis of the interdisciplinary literature identified. We describe partnership opportunities, benefits and challenges; and tools and approaches to help NGO engage with the private sector to address global public health nutrition challenges. PPP benefits include: raising the visibility of nutrition and health on policy agendas; mobilizing funds and advocating for research; strengthening food-system processes and delivery systems; facilitating technology transfer; and expanding access to medications, vaccines, healthy food and beverage products, and nutrition assistance during humanitarian crises. PPP challenges include: balancing private commercial interests with public health interests; managing conflicts of interest; ensuring that co-branded activities support healthy products and healthy eating environments; complying with ethical codes of conduct; assessing partnership compatibility; and evaluating partnership outcomes. NGO should adopt a systematic and transparent approach using available tools and processes to maximize benefits and minimize risks of partnering with transnational food, beverage and restaurant companies to effectively target the global double burden of malnutrition.

  7. Who governs energy? The challenges facing global energy governance

    Energy Technology Data Exchange (ETDEWEB)

    Florini, Ann; Sovacool, Benjamin K. [Centre on Asia and Globalisation, Lee Kuan Yew School of Public Policy, National University of Singapore, Singapore 259772 (Singapore)

    2009-12-15

    This article conceptualizes the energy problems facing society from a global governance perspective. It argues that a notion of 'global energy governance,' taken to mean international collective action efforts undertaken to manage and distribute energy resources and provide energy services, offers a meaningful and useful framework for assessing energy-related challenges. The article begins by exploring the concepts of governance, global governance, and global energy governance. It then examines some of the existing institutions in place to establish and carry out rules and norms governing global energy problems and describes the range of institutional design options available to policymakers. It briefly traces the role of a selection of these institutions, from inter-governmental organizations to summit processes to multilateral development banks to global action networks, in responding to energy issues, and points out their strengths and weaknesses. The article concludes by analyzing how the various approaches to global governance differ in their applicability to addressing the conundrums of global energy problems. (author)

  8. Time for a change: addressing R&D and commercialization challenges for antibacterials

    Science.gov (United States)

    Payne, David J.; Miller, Linda Federici; Findlay, David; Anderson, James; Marks, Lynn

    2015-01-01

    The antibacterial therapeutic area has been described as the perfect storm. Resistance is increasing to the point that our hospitals encounter patients infected with untreatable pathogens, the overall industry pipeline is described as dry and most multinational pharmaceutical companies have withdrawn from the area. Major contributing factors to the declining antibacterial industry pipeline include scientific challenges, clinical/regulatory hurdles and low return on investment. This paper examines these challenges and proposes approaches to address them. There is a need for a broader scientific agenda to explore new approaches to discover and develop antibacterial agents. Additionally, ideas of how industry and academia could be better integrated will be presented. While promising progress in the regulatory environment has been made, more streamlined regulatory paths are still required and the solutions will lie in global harmonization and clearly defined guidance. Creating the right incentives for antibacterial research and development is critical and a new commercial model for antibacterial agents will be proposed. One key solution to help resolve both the problem of antimicrobial resistance (AMR) and lack of new drug development are rapid, cost-effective, accurate point of care diagnostics that will transform antibacterial prescribing and enable more cost-effective and efficient antibacterial clinical trials. The challenges of AMR are too great for any one group to resolve and success will require leadership and partnerships among academia, industry and governments globally. PMID:25918443

  9. Time for a change: addressing R&D and commercialization challenges for antibacterials.

    Science.gov (United States)

    Payne, David J; Miller, Linda Federici; Findlay, David; Anderson, James; Marks, Lynn

    2015-06-05

    The antibacterial therapeutic area has been described as the perfect storm. Resistance is increasing to the point that our hospitals encounter patients infected with untreatable pathogens, the overall industry pipeline is described as dry and most multinational pharmaceutical companies have withdrawn from the area. Major contributing factors to the declining antibacterial industry pipeline include scientific challenges, clinical/regulatory hurdles and low return on investment. This paper examines these challenges and proposes approaches to address them. There is a need for a broader scientific agenda to explore new approaches to discover and develop antibacterial agents. Additionally, ideas of how industry and academia could be better integrated will be presented. While promising progress in the regulatory environment has been made, more streamlined regulatory paths are still required and the solutions will lie in global harmonization and clearly defined guidance. Creating the right incentives for antibacterial research and development is critical and a new commercial model for antibacterial agents will be proposed. One key solution to help resolve both the problem of antimicrobial resistance (AMR) and lack of new drug development are rapid, cost-effective, accurate point of care diagnostics that will transform antibacterial prescribing and enable more cost-effective and efficient antibacterial clinical trials. The challenges of AMR are too great for any one group to resolve and success will require leadership and partnerships among academia, industry and governments globally. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  10. Addressing the pressing need to reduce global and European imbalances

    OpenAIRE

    Cozzi, Giovanni; McKinley, Terry

    2015-01-01

    This Policy Brief is focused on the need to reduce macroeconomic imbalances both globally and within Europe. In doing so, it employs the CAM global macroeconometric model to make projections of trends over roughly the next ten years, i.e., through 2025.

  11. Adoptive T cell therapy: Addressing challenges in cancer immunotherapy

    Directory of Open Access Journals (Sweden)

    Yee Cassian

    2005-04-01

    Full Text Available Abstract Adoptive T cell therapy involves the ex vivo selection and expansion of effector cells for the treatment of patients with cancer. In this review, the advantages and limitations of using antigen-specific T cells are discussed in counterpoint to vaccine strategies. Although vaccination strategies represent more readily available reagents, adoptive T cell therapy provides highly selected T cells of defined phenotype, specificity and function that may influence their biological behavior in vivo. Adoptive T cell therapy offers not only translational opportunities but also a means to address fundamental issues in the evolving field of cancer immunotherapy.

  12. North American Water Program (NAWP): A Vision to Address North America's Freshwater Sustainability Challenges

    Science.gov (United States)

    Belvedere, D. R.; Houser, P. R.; Schiffer, R. A.; Entin, J. K.

    2013-12-01

    Dramatically changing climates has had an indelible impact on North America's water crisis; the rapid melting of glaciers has profound implications for the sustainability of Canada's rivers. However, projective increases in water demand from increasing population, industrial energy, and agriculture needs may have four times more impact on the water supply-demand imbalance than climate change. Reliable prediction of hydrologic change and extremes is of critical importance for policy and decision makers to adapt to these future water challenges. However, the models that we use to understand and forecast water availability, flooding, and drought are simply not up to the task of addressing our most pressing societal issues and national security. We need a decisive and coordinative effort to systematically improve water cycle prediction skill, coupled with reliable methodologies to translate those predictions into actionable water supply and quality information to support sustainable water management - this is a primary motivation for the proposed North American Water Program (NAWP). To decisively address these challenges, we recommend that NAWP coalesce an interdisciplinary, international and interagency effort to make significant contributions to continental-to-decision-scale hydroclimate science and solutions. By entraining, integrating and coordinating the vast array of interdisciplinary observationable and prediction resources available, NAWP will significantly advance skill in predicting, assessing, and managing variability and changes in North American water resources, as an integral part of the global climate system. We adopt three challenges to organize NAWP efforts. The first deals with developing a scientific basis and tools for mitigating and adapting to changes in the water supply-demand balance. The second challenge is benchmarking; to use incomplete and uncertain observations to assess water storage and quality dynamics, and to characterize the

  13. Public engagement on global health challenges

    Directory of Open Access Journals (Sweden)

    Minhas Gunjeet S

    2008-05-01

    Full Text Available Abstract Background Experience with public engagement activities regarding the risks and benefits of science and technology (S&T is growing, especially in the industrialized world. However, public engagement in the developing world regarding S&T risks and benefits to explore health issues has not been widely explored. Methods This paper gives an overview about public engagement and related concepts, with a particular focus on challenges and benefits in the developing world. We then describe an Internet-based platform, which seeks to both inform and engage youth and the broader public on global water issues and their health impacts. Finally, we outline a possible course for future action to scale up this and similar online public engagement platforms. Results The benefits of public engagement include creating an informed citizenry, generating new ideas from the public, increasing the chances of research being adopted, increasing public trust, and answering ethical research questions. Public engagement also fosters global communication, enables shared experiences and methodology, standardizes strategy, and generates global viewpoints. This is especially pertinent to the developing world, as it encourages previously marginalized populations to participate on a global stage. One of the core issues at stake in public engagement is global governance of science and technology. Also, beyond benefiting society at large, public engagement in science offers benefits to the scientific enterprise itself. Conclusion Successful public engagement with developing world stakeholders will be a critical part of implementing new services and technologies. Interactive engagement platforms, such as the Internet, have the potential to unite people globally around relevant health issues.

  14. Expanding the role for psychology in addressing environmental challenges.

    Science.gov (United States)

    Clayton, Susan; Devine-Wright, Patrick; Swim, Janet; Bonnes, Mirilia; Steg, Linda; Whitmarsh, Lorraine; Carrico, Amanda

    2016-04-01

    Environmental challenges, though daunting, present an important area for psychologists to apply their knowledge. Psychological theories, research methods, and interventions are essential for examining the questions about human impacts, tendencies, and capacities that are integral to constructing effective responses to these challenges. Although a great deal of relevant research has been done, there is scope for psychologists to be more extensively involved. Following a brief review of existing research, we outline some important new directions. We also highlight 2 key divergences, arguing that psychological research needs to expand beyond a traditional, theory-based and decontextualized approach to environmental issues to incorporate a contextualized or "place-based" approach and a willingness to collaborate in interdisciplinary research teams that focus on specific environmental problems. Suggestions for promoting such interdisciplinary collaborations are reviewed. We encourage psychologists to expand their engagement with important environmental issues through multiple research approaches in order to further their understanding of human behavior, contributions to human well-being, and relevance to other disciplines and to society.

  15. Attaining global health: challenges and opportunities.

    Science.gov (United States)

    Ratzan, S C; Filerman, G L; Lesar, J W

    2000-03-01

    This issue of the Population Bulletin examines health trends in both developed and developing regions using health measures such as mortality and morbidity and the disability-adjusted life year. It also assesses the challenge of improving health worldwide. The authors proposed the following common denominators in the global challenge to improve health: 1) an individual's health status reflects the interplay of many factors such as the physical environment, political stability, and community structure; 2) direct correlation between the population's level of health and educational levels within that population; 3) prudent use of existing resources may contribute to a healthier public; 4) both public sector and private sector resources are vital for obtaining the best health possible; 5) effective infrastructure for health delivery requires fundamental changes in how governments and health system operate; and 6) policies to promote health are key components of community health efforts.

  16. Making Norms to Tackle Global Challenges

    DEFF Research Database (Denmark)

    Nilsson, Adriana

    2017-01-01

    This paper argues that Intergovernmental Organisations (IGOs) can play a significant role in the processes of system transformation required by Grand Challenges. The reason is their potential to influence socio-technical regimes connected to policy areas in which they have authority. Supported...... public and private actors, IGOs implement and protect novel practices that reinforce the new norms, from legally binding agreements to the creation of new spaces for international collaboration. These processes are examined here in the field of global health, where outside pressure directed...

  17. Strategies to Address Common Challenges When Teaching in an Active Learning Classroom

    Science.gov (United States)

    Petersen, Christina I.; Gorman, Kristen S.

    2014-01-01

    This chapter provides practical strategies for addressing common challenges that arise for teachers in active learning classrooms. Our strategies come from instructors with experience teaching in these environments.

  18. Strategies to Address Common Challenges When Teaching in an Active Learning Classroom

    Science.gov (United States)

    Petersen, Christina I.; Gorman, Kristen S.

    2014-01-01

    This chapter provides practical strategies for addressing common challenges that arise for teachers in active learning classrooms. Our strategies come from instructors with experience teaching in these environments.

  19. Oral health in Libya: addressing the future challenges.

    Science.gov (United States)

    Peeran, Syed Wali; Altaher, Omar Basheer; Peeran, Syed Ali; Alsaid, Fatma Mojtaba; Mugrabi, Marei Hamed; Ahmed, Aisha Mojtaba; Grain, Abdulgader

    2014-01-01

    Libya is a vast country situated in North Africa, having a relatively better functioning economy with a scanty population. This article is the first known attempt to review the current state of oral health care in Libya and to explore the present trends and future challenges. Libyan health system, oral health care, and human resources with the present status of dental education are reviewed comprehensively. A bibliographic study of oral health research and publications has been carried out. The results point toward a common indicator that oral health-related research is low. Strategies have to be developed to educate the medical and dental professionals, to update the current curriculum and enable the system to be competent in all aspects of oral health care management.

  20. Addressing new analytical challenges in protein formulation development.

    Science.gov (United States)

    Mach, Henryk; Arvinte, Tudor

    2011-06-01

    As the share of therapeutic proteins in the arsenal of modern medicine continue increasing, relatively little progress has been made in the development of analytical methods that would address specific needs encountered during the development of these new drugs. Consequently, the researchers resort to adaptation of existing instrumentation to meet the demands of rigorous bioprocess and formulation development. In this report, we present a number of such adaptations as well as new instruments that allow efficient and precise measurement of critical parameters throughout the development stage. The techniques include use of atomic force microscopy to visualize proteinacious sub-visible particles, use of extrinsic fluorescent dyes to visualize protein aggregates, particle tracking analysis, determination of the concentration of monoclonal antibodies by the analysis of second-derivative UV spectra, flow cytometry for the determination of subvisible particle counts, high-throughput fluorescence spectroscopy to study phase separation phenomena, an adaptation of a high-pressure liquid chromatography (HPLC) system for the measurement of solution viscosity and a variable-speed streamlined analytical ultracentrifugation method. An ex vivo model for understanding the factors that affect bioavailability after subcutaneous injections is also described. Most of these approaches allow not only a more precise insight into the nature of the formulated proteins, but also offer increased throughput while minimizing sample requirements.

  1. Addressing a nation's challenge: graduate programs in gerontology in Israel.

    Science.gov (United States)

    Carmel, Sara; Lowenstein, Ariela

    2007-01-01

    Like other developed nations, Israel has rapidly aged. This demographic revolution has created new challenges for Israeli society. We describe the societal background, including the emerging societal needs, solutions, and problems, as well as the professional principles, which guided us in developing the first two Israeli academic programs in gerontology in Beer-Sheva and Haifa. We further discuss the structures of both programs and their accomplishments. Although both programs were guided by identical needs and principles, geared toward the same multidisciplinary target population, and are dynamic and responsive to the emerging needs and difficulties, they differ in structure. While Haifa's program is flexible, Beer-Sheva's program is structured and divided into three distinct programs, of which only one-the research track-is designed and tailored to the students' interest. The two programs have contributed to increasing interest and research in aging in Israel, enhancing professional cooperation within the universities and with the international scientific community, opening the labor market for the programs' graduates, creating fruitful collaborations with community services, and accelerating the improvement of elderly quality of care.

  2. Aneesur Rahman Prize for Computational Physics Lecture: Addressing Dirac's Challenge

    Science.gov (United States)

    Chelikowsky, James

    2013-03-01

    After the invention of quantum mechanics, P. A. M. Dirac made the following observation: ``The underlying physical laws necessary for the mathematical theory of a large part of physics and the whole of chemistry are thus completely known, and the difficulty is only that the exact application of these laws leads to equations much too complicated to be soluble. It therefore becomes desirable that approximate practical methods of applying quantum mechanics should be developed, which can lead to an explanation of the main features of complex atomic systems...'' The creation of ``approximate practical methods'' in response to Dirac's challenge has included the one electron picture, density functional theory and the pseudopotential concept. The combination of such methods in conjunction with contemporary computational platforms and new algorithms offer the possibility of predicting properties of materials solely from knowledge of the atomic species present. I will give an overview of progress in this field with an emphasis on materials at the nanoscale. Support from the Department of Energy and the National Science Foundation is acknowledged.

  3. Peptide immunotherapy for childhood allergy - addressing translational challenges

    Directory of Open Access Journals (Sweden)

    Mackenzie Karen J

    2011-11-01

    Full Text Available Abstract Allergic sensitisation usually begins early in life. The number of allergens a patient is sensitised to can increase over time and the development of additional allergic conditions is increasingly recognised. Targeting allergic disease in childhood is thus likely to be the most efficacious means of reducing the overall burden of allergic disease. Specific immunotherapy involves administering protein allergen to tolerise allergen reactive CD4+ T cells, thought key in driving allergic responses. Yet specific immunotherapy risks allergic reactions including anaphylaxis as a consequence of preformed allergen-specific IgE antibodies binding to the protein, subsequent cross-linking and mast cell degranulation. CD4+ T cells direct their responses to short "immunodominant" peptides within the allergen. Such peptides can be given therapeutically to induce T cell tolerance without facilitating IgE cross-linking. Peptide immunotherapy (PIT offers attractive treatment potential for allergic disease. However, PIT has not yet been shown to be effective in children. This review discusses the immunological mechanisms implicated in PIT and briefly covers outcomes from adult PIT trials. This provides a context for discussion of the challenges for the application of PIT, both generally and more specifically in relation to children.

  4. Breast cancer: unique communication challenges and strategies to address them.

    Science.gov (United States)

    Parker, Patricia A; Aaron, Joann; Baile, Walter F

    2009-01-01

    Women with breast cancer have become increasingly more involved on a national and local level in advocating for resources to fight cancer. However, in the context of the relationship with their physicians and other cancer caregivers, much remains to be done in providing them with adequate support. In this paper, we highlight the difficulties in communication related to breast cancer and describe strategies and approaches that may be helpful in improving the communication throughout the cancer trajectory. Specifically, breast cancer patients have high unmet information needs relevant to health information and dissatisfaction with the actual information they receive from their providers. These needs seem even more pronounced when patients are older, of lower socio-economic class and from differing cultural backgrounds which may affect their ability to express their desires for information and desire to be involved in decision-making about their treatment. Other communication challenges can be envisioned as occurring at key points across the cancer trajectory: diagnosis disclosure, treatment failure, transition to palliative care, and end of life discussions. These involve techniques as basic as how to establish trust and rapport and determine a patient's information and decision-making preferences and as complex as giving bad news. These strategies are now viewed as essential skills in that they can affect patient distress and quality of life, satisfaction, and malpractice litigation as well as practitioner stress and burnout.

  5. Addressing the Challenge: Cataloguing Electronic Books in Academic Libraries

    Directory of Open Access Journals (Sweden)

    Shuzhen Zhao

    2010-03-01

    Full Text Available Objective ‐ This paper explores the various issues and challenges arising from e‐book cataloguing experienced at the University of Windsor’s Leddy Library and the Ontario Council of University Libraries (OCUL. This discussion uses an evidence based approach to identify and resolve issues relevant to academic libraries as well as to consortia. With the ever rising popularity of e‐books within academic libraries, cataloguing librarians are actively seeking more effective methods of managing this new electronic medium, including the development of new cataloguing policies and procedures. This paper will explore the various issues and challenges surrounding e‐book cataloguing and processing within academic libraries, and will identify new policies and procedures that may be used to effectively assist in e‐book management.Methods ‐ This paper presents a case study of e‐book cataloguing practices undertaken by a Canadian academic library and the consortium with which it is affiliated. Towards this end, the University of Windsor’s Leddy Library will be the prime focus of this study, with its establishment of a new e‐book MARC records database. The research is based on the results of the e‐book MARC project undertaken by the Leddy Library and the Ontario Council of University Libraries (OCUL.Through analysis of various suppliers’ MARC records and the actual implementation of the e‐book MARC project, the authors developed and evaluated a new approach to e‐book cataloguing for use in academic libraries.Results ‐ This practice‐based approach towards the development of a new method of e‐book cataloguing required continual modification and examination of e‐book MARC records within the target library. The Leddy Library’s e‐book MARC project provided an excellent opportunity to test the library’s existing cataloguing standards and procedures for print format, while at the same time, identifying related e‐books issues

  6. Intercultural Identities: Addressing the Global Dimension through Art Education

    Science.gov (United States)

    Bianchi, June

    2011-01-01

    Recent educational policy and practice have established an extended role for all subjects in addressing children and young peoples' academic and interpersonal development, with strategies facilitating key skills and wider learning across areas of Citizenship and Personal, Social and Health education providing an integrated approach to education…

  7. Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health

    Directory of Open Access Journals (Sweden)

    Eric Miller

    2015-06-01

    Full Text Available Immunochromatographic rapid diagnostic tests (RDTs have demonstrated significant potential for use as point-of-care diagnostic tests in resource-limited settings. Most notably, RDTs for malaria have reached an unparalleled level of technological maturity and market penetration, and are now considered an important complement to standard microscopic methods of malaria diagnosis. However, the technical development of RDTs for other infectious diseases, and their uptake within the global health community as a core diagnostic modality, has been hindered by a number of extant challenges. These range from technical and biological issues, such as the need for better affinity agents and biomarkers of disease, to social, infrastructural, regulatory and economic barriers, which have all served to slow their adoption and diminish their impact. In order for the immunochromatographic RDT format to be successfully adapted to other disease targets, to see widespread distribution, and to improve clinical outcomes for patients on a global scale, these challenges must be identified and addressed, and the global health community must be engaged in championing the broader use of RDTs.

  8. Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health.

    Science.gov (United States)

    Miller, Eric; Sikes, Hadley D

    Immunochromatographic rapid diagnostic tests (RDTs) have demonstrated significant potential for use as point-of-care diagnostic tests in resource-limited settings. Most notably, RDTs for malaria have reached an unparalleled level of technological maturity and market penetration, and are now considered an important complement to standard microscopic methods of malaria diagnosis. However, the technical development of RDTs for other infectious diseases, and their uptake within the global health community as a core diagnostic modality, has been hindered by a number of extant challenges. These range from technical and biological issues, such as the need for better affinity agents and biomarkers of disease, to social, infrastructural, regulatory and economic barriers, which have all served to slow their adoption and diminish their impact. In order for the immunochromatographic RDT format to be successfully adapted to other disease targets, to see widespread distribution, and to improve clinical outcomes for patients on a global scale, these challenges must be identified and addressed, and the global health community must be engaged in championing the broader use of RDTs.

  9. Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health

    Directory of Open Access Journals (Sweden)

    Eric Miller

    2015-06-01

    Full Text Available Immunochromatographic rapid diagnostic tests (RDTs have demonstrated significant potential for use as point-of- care diagnostic tests in resource-limited settings. Most notably, RDTs for malaria have reached an unparalleled level of technological maturity and market penetration, and are now considered an important complement to standard microscopic methods of malaria diagnosis. However, the technical development of RDTs for other infectious diseases, and their uptake within the global health community as a core diagnostic modality, has been hindered by a number of extant challenges. These range from technical and biological issues, such as the need for better affinity agents and biomarkers of disease, to social, infrastructural, regulatory and economic barriers, which have all served to slow their adoption and diminish their impact. In order for the immunochromatographic RDT format to be successfully adapted to other disease targets, to see widespread distribution, and to improve clinical outcomes for patients on a global scale, these challenges must be identified and addressed, and the global health community must be engaged in championing the broader use of RDTs.

  10. Addressing China's grand challenge of achieving food security while ensuring environmental sustainability.

    Science.gov (United States)

    Lu, Yonglong; Jenkins, Alan; Ferrier, Robert C; Bailey, Mark; Gordon, Iain J; Song, Shuai; Huang, Jikun; Jia, Shaofeng; Zhang, Fusuo; Liu, Xuejun; Feng, Zhaozhong; Zhang, Zhibin

    2015-02-01

    China's increasingly urbanized and wealthy population is driving a growing and changing demand for food, which might not be met without significant increase in agricultural productivity and sustainable use of natural resources. Given the past relationship between lack of access to affordable food and political instability, food security has to be given a high priority on national political agendas in the context of globalization. The drive for increased food production has had a significant impact on the environment, and the deterioration in ecosystem quality due to historic and current levels of pollution will potentially compromise the food production system in China. We discuss the grand challenges of not only producing more food but also producing it sustainably and without environmental degradation. In addressing these challenges, food production should be considered as part of an environmental system (soil, air, water, and biodiversity) and not independent from it. It is imperative that new ways of meeting the demand for food are developed while safeguarding the natural resources upon which food production is based. We present a holistic approach to both science and policy to ensure future food security while embracing the ambition of achieving environmental sustainability in China. It is a unique opportunity for China to be a role model as a new global player, especially for other emerging economies.

  11. Danish and global climate and energy challenges

    Energy Technology Data Exchange (ETDEWEB)

    Christensen, John M. (Risoe DTU, Roskilde (Denmark)); Davidson, O. (Univ. of Sierra Leone, IPCC (Sierra Leone))

    2008-12-15

    The global energy scene is currently dominated by two overriding concerns that are strongly affecting decisions about energy development priorities: 1) Climate change 2) Energy security. This is especially true for industrialized countries and the more rapidly developing economies while many developing countries are facing really basic energy development constraints giving quite a different meaning to the concept of energy security. There is broad global recognition of the need to support these countries in their efforts to increase access to cleaner and more efficient forms of energy for the more than 1,6 billion people currently having no access to electricity and largely relying on traditional forms of biomass for basic energy services, but progress is slow in many regions. The three areas, security, climate and poverty are in several ways interlinked, and ideally national energy policies and development programmes should address all the above issues - or at least not have negative effects in any area. In practice, however, many national policy landscapes have been dominated by just one of these factors. In the political debate the access issue is often seen as a potential climate problem, but most studies indicate that access to basic energy services for the poorest one billion people, even based on fossil resources, will make very marginal contributions to global GHG emissions. The more relevant and pressing political concern is how to limit global emissions and allow the emerging economies to continue their economic growth, but as discussed in this report the technological options will be available and solutions depend on political will and agreements on sharing the technologies and financial resources. (au)

  12. An effective way to address global environmental and energy problems

    Science.gov (United States)

    Andrienko, O.; Garelina, S.; Gysev, A.; Zakharyan, R.; Kazaryan, M.; Sachkov, V.

    2015-12-01

    This work scales the present globalism of ecological and energetic problems. The ecological problem is connected with environment pollution by polymeric waste. The energetic problem - with traditional approaches of modern energetic, in particular, use of fossil fuel for energy production and concentration of capacities for ensuring overall performance of global power supply systems that doesn't guarantee a sustainable development of power for long prospect, doesn't provide power safety of the country. The second part of work is devoted to a choice of the most effective solutions of the present global problems. The authors have proposed the plasma-chemical method of the polymer waste processing and developed a schematic diagram of the reactor. The paper contains the results of the theoretical calculation of the polymer waste processing products. The reagents, allowing to obtain hydrogen and other liquid products from polymer waste are selected. It is proposed to use rare elements for increasing the efficiency of hydrogen production from polymer waste. The results of the calculation of the efficiency of hydrogen production from polymer waste using molybdenum are revealed in the paper.

  13. Facing Global Challenges with Materials Innovation

    Science.gov (United States)

    Rizzo, Fernando

    2017-08-01

    The path of society evolution has long been associated with a growing demand for natural resources and continuous environmental degradation. During the last decades, this pace has accelerated considerably, despite the general concern with the legacy being left for the next generations. Looking ahead, the predicted growth of the world population, and the improvement of life conditions in most regions, point to an increasing demand for energy generation, resulting in additional pressure on the Earth's sustainability. Materials have had a key role in decreasing the use of natural resources, by either improving efficiency of existing technologies or enabling the development of radical new ones. The greenhouse effect (CO2 emissions) and the energy crisis are global challenges that can benefit from the development of new materials for the successful implementation of promising technologies and for the imperative replacement of fossil fuels by renewable sources.

  14. Facing Global Challenges with Materials Innovation

    Science.gov (United States)

    Rizzo, Fernando

    2017-10-01

    The path of society evolution has long been associated with a growing demand for natural resources and continuous environmental degradation. During the last decades, this pace has accelerated considerably, despite the general concern with the legacy being left for the next generations. Looking ahead, the predicted growth of the world population, and the improvement of life conditions in most regions, point to an increasing demand for energy generation, resulting in additional pressure on the Earth's sustainability. Materials have had a key role in decreasing the use of natural resources, by either improving efficiency of existing technologies or enabling the development of radical new ones. The greenhouse effect (CO2 emissions) and the energy crisis are global challenges that can benefit from the development of new materials for the successful implementation of promising technologies and for the imperative replacement of fossil fuels by renewable sources.

  15. Biological approaches for addressing the grand challenge of providing access to clean drinking water

    OpenAIRE

    Gerba Charles P; Riley Mark R; Elimelech Menachem

    2011-01-01

    Abstract The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of p...

  16. Large system change challenges: addressing complex critical issues in linked physical and social domains

    Science.gov (United States)

    Waddell, Steve; Cornell, Sarah; Hsueh, Joe; Ozer, Ceren; McLachlan, Milla; Birney, Anna

    2015-04-01

    Most action to address contemporary complex challenges, including the urgent issues of global sustainability, occurs piecemeal and without meaningful guidance from leading complex change knowledge and methods. The potential benefit of using such knowledge is greater efficacy of effort and investment. However, this knowledge and its associated tools and methods are under-utilized because understanding about them is low, fragmented between diverse knowledge traditions, and often requires shifts in mindsets and skills from expert-led to participant-based action. We have been engaged in diverse action-oriented research efforts in Large System Change for sustainability. For us, "large" systems can be characterized as large-scale systems - up to global - with many components, of many kinds (physical, biological, institutional, cultural/conceptual), operating at multiple levels, driven by multiple forces, and presenting major challenges for people involved. We see change of such systems as complex challenges, in contrast with simple or complicated problems, or chaotic situations. In other words, issues and sub-systems have unclear boundaries, interact with each other, and are often contradictory; dynamics are non-linear; issues are not "controllable", and "solutions" are "emergent" and often paradoxical. Since choices are opportunity-, power- and value-driven, these social, institutional and cultural factors need to be made explicit in any actionable theory of change. Our emerging network is sharing and building a knowledge base of experience, heuristics, and theories of change from multiple disciplines and practice domains. We will present our views on focal issues for the development of the field of large system change, which include processes of goal-setting and alignment; leverage of systemic transitions and transformation; and the role of choice in influencing critical change processes, when only some sub-systems or levels of the system behave in purposeful ways

  17. Global panorama of energy access: Current situation, challenges and outlook

    Energy Technology Data Exchange (ETDEWEB)

    Galichon, Ines; Lacroix, Olivier; Wiedmer, Damien

    2014-07-15

    Globally 1.3 billion people do not have access to electricity. If this figure is projected to decline 1 billion by 2030, the global population who relies on the traditional use of biomass for cooking is expected to substantially increase, from 2.6 billion to 2.7 billion people. In its commitment to energy access, ENEA published a synthesis on the current situation and the further development perspectives of energy access worldwide, a crucial issue of human and economic development and an opportunity for the private sector. This synthesis present the ecosystem of the actors involved in the improvement of energy access and the technical solutions that serve the needs of this high-potential market. The five main challenges energy access has to address are presented in this publication: energy prices, equipment financing, distribution, change of scale and environmental performances.

  18. Preparing for Change: Challenges and Opportunities in a Global World

    Science.gov (United States)

    O'Hara, Sabine

    2009-03-01

    Our world is becoming increasingly global. This may sound like a clich'e, yet it is true nonetheless, and poses unprecedented challenges for graduate education. For the new generation of researchers, teachers and professionals to be successful they must be prepared in more than the content area of their chosen field. They must also acquire proficiency in global awareness, cultural literacy, multicultural teamwork and language facility. These global skill sets form the basis for effective multicultural collaboration and will become increasingly important even for those who do not intend to study or work abroad. Knowledge has become more portable in the internet age; large data bases and reports can be accessed in real time from various locations around the globe; information is exchanged in multifaceted knowledge networks; collaborative research takes place within and outside of the traditional venue of the research university in the private sector, research institutes, and associations; research networks span multiple disciplines as progress invariably occurs at the intersection of previously discrete fields of inquiry. Global collaboration thus is no longer dependent on the physical proximity of collaborators but can take place anywhere any time. This then requires yet another set of skills, namely the ability to adapt to change, exhibit flexibility and transfer skills to a range of contexts and applications. Effective graduate education must address these realities and expose students to learning opportunities that will enable them to acquire these much needed global skills sets.

  19. Workshop Builds Strategies to Address Global Positioning System Vulnerabilities

    Science.gov (United States)

    Fisher, Genene

    2011-01-01

    When we examine the impacts of space weather on society, do we really understand the risks? Can past experiences reliably predict what will happen in the future? As the complexity of technology increases, there is the potential for it to become more fragile, allowing for a single point of failure to bring down the entire system. Take the Global Positioning System (GPS) as an example. GPS positioning, navigation, and timing have become an integral part of daily life, supporting transportation and communications systems vital to the aviation, merchant marine, cargo, cellular phone, surveying, and oil exploration industries. Everyday activities such as banking, mobile phone operations, and even the control of power grids are facilitated by the accurate timing provided by GPS. Understanding the risks of space weather to GPS and the many economic sectors reliant upon it, as well as how to build resilience, was the focus of a policy workshop organized by the American Meteorological Society (AMS) and held on 13-14 October 2010 in Washington, D. C. The workshop brought together a select group of policy makers, space weather scientists, and GPS experts and users.

  20. Coping with global environmental change, disasters and security: threats, challenges, vulnerabilities and risks

    NARCIS (Netherlands)

    Brauch, H.G.; Oswald Spring, Ú.; Mesjasz, C.; Grin, J.; Kameri-Mbote, P.; Chourou, B.; Dunay, P.; Birkmann, J.

    2011-01-01

    This policy-focused Global Environmental and Human Security Handbook for the Anthropo-cene (GEHSHA) addresses new security threats, challenges, vulnerabilities and risks posed by global environmental change and disasters. In 6 forewords, 5 preface essays 95 peer reviewed chapcountries analyse in 10

  1. Challenges of creating synergy between global mental health and cultural psychiatry

    NARCIS (Netherlands)

    de Jong, J.T.V.M.

    2014-01-01

    This article addresses four major challenges for efforts to create synergy between the global mental health movement and cultural psychiatry. First, although they appear to share domains of mutual interest, the worlds of global mental health and cultural psychiatry have distinct lineages. Expanding

  2. Coping with global environmental change, disasters and security: threats, challenges, vulnerabilities and risks

    NARCIS (Netherlands)

    Brauch, H.G.; Oswald Spring, Ú.; Mesjasz, C.; Grin, J.; Kameri-Mbote, P.; Chourou, B.; Dunay, P.; Birkmann, J.

    2011-01-01

    This policy-focused Global Environmental and Human Security Handbook for the Anthropo-cene (GEHSHA) addresses new security threats, challenges, vulnerabilities and risks posed by global environmental change and disasters. In 6 forewords, 5 preface essays 95 peer reviewed chapcountries analyse in 10

  3. The New Global Governance Architectures on Grand Challenges and State Capacity

    DEFF Research Database (Denmark)

    Borrás, Susana

    During the past decade there has been a rapid emergence of new forms of global governance architectures seeking to address grand challenges. International organizations and other strong actors in the global scene have been setting up new, ambitious, open-ended and solutionoriented architectures...

  4. Addressing the Global Burden of Trauma in Major Surgery

    Directory of Open Access Journals (Sweden)

    Geoffrey Phillip Dobson

    2015-09-01

    Full Text Available Despite a technically perfect procedure, surgical stress can determine the success or failure of an operation. Surgical trauma is often referred to as the neglected step-child of global health in terms of patient numbers, mortality, morbidity and costs. A staggering 234 million major surgeries are performed every year, and depending upon country and institution, up to 4% of patients will die before leaving hospital, up to 15% will have serious post-operative morbidity, and 5 to 15% will be readmitted within 30 days. These percentages equate to around 1000 deaths and 4000 major complications every hour, and it has been estimated that 50% may be preventable. New frontline drugs are urgently required to make major surgery safer for the patient and more predictable for the surgeon. We review the basic physiology of the stress response from neuroendocrine to genomic systems, and discuss the paucity of clinical data supporting the use of statins, beta-adrenergic blockers and calcium channel blockers. Since cardiac-related complications are the most common, particularly in the elderly, a key strategy would be to improve ventricular-arterial coupling to safeguard the endothelium and maintain tissue oxygenation. Reduced O2 supply is associated with glycocalyx shedding, decreased endothelial barrier function, fluid leakage, inflammation and coagulopathy. A healthy endothelium may prevent these secondary hit complications, including possibly immunosuppression. Thus the four pillars of whole body resynchronization during surgical trauma, and targets for new therapies, are: 1 the CNS, 2 the heart, 3 arterial supply and venous return functions, and 4 the endothelium. This is termed the Central-Cardio-Vascular-Endothelium (CCVE coupling hypothesis. Since similar sterile injury cascades exist in critical illness, accidental trauma, hemorrhage, cardiac arrest, infection and burns, new drugs that improve CCVE coupling may find wide utility in civilian and

  5. Probing Matter-Field and Atom-Number Correlations in Optical Lattices by Global Nondestructive Addressing

    CERN Document Server

    Kozlowski, Wojciech; Mekhov, Igor B

    2014-01-01

    We show that light scattering from an ultracold gas reveals not only density correlations, but also matter-field interference at its shortest possible distance in an optical lattice, which defines key properties such as tunneling and matter-field phase gradients. This signal can be enhanced by concentrating probe light between lattice sites rather than at density maxima. As addressing between two single sites is challenging, we focus on global nondestructive scattering, allowing probing order parameters, matter-field quadratures and their squeezing. The scattering angular distribution displays peaks even if classical diffraction is forbidden and we derive generalized Bragg conditions. Light scattering distinguishes all phases in the Mott insulator - superfluid - Bose glass phase transition.

  6. Critical Zone Science and Global Societal Challenges

    Science.gov (United States)

    Goldhaber, M. B.; Banwart, S. A.

    2014-12-01

    Earth's Critical Zone (CZ) is the thin outer veneer of our planet from the top of the tree canopy to the bottom of our drinking water aquifers that supports almost all human activity. Despite its fundamental importance to terrestrial life, understanding of the operation of the coupled geologic, hydrologic, topographic, and biotic CZ processes across time and space is far from complete. These interactions are complex and they establish a mechanistic 'chain of impact' that transmits the effects of environmental change throughout the CZ. Characterization of these processes is made more urgent by the fact that globally, the CZ is experiencing ever-increasing pressure from growth in human population and wealth. Within the next four decades, demand for food and fuel is expected to double along with a more than 50% increase in demand for clean water. Understanding, predicting and managing intensification of land use and associated economic services, while mitigating and adapting to rapid climate change, is now one of the most pressing societal challenges of the 21st century. In this talk we summarize the profound global societal impacts to the Earth's near surface arising from exponential human population growth, increasing affluence, and technological advance, to provide context for discussions on constructing an array of CZ observatories to both characterize fundamental critical zone processes and forecast the effects of planetary change. We will suggest goals and options relevant to planning for a future international array of CZ observatories and a research agenda that matches the urgency of the projected resource demands and environmental pressures of the coming four decades.

  7. The New Global Responsibilities of Engineers Create Challenges for Engineering Education

    Science.gov (United States)

    Fuchs, Willi

    2012-01-01

    Modern societies aim to solve the global challenges of the 21st century with sustainable solutions such as resource efficiency, use of renewable energy sources and recycling. Engineers are called upon to create the cutting edge technological solutions that can help to address these challenges. In developed as well as in developing countries,…

  8. Energy-Intensive Processes Portfolio: Addressing Key Energy Challenges Across U.S. Industry

    Energy Technology Data Exchange (ETDEWEB)

    None

    2011-03-07

    AMO is developing advanced technologies that cut energy use and carbon emissions in some of the most energy-intensive processes within U.S. manufacturing. The brochure describes the AMO R&D projects that address these challenges.

  9. Megacities and Large Urban Complexes - WMO Role in Addressing Challenges and Opportunities

    Science.gov (United States)

    Terblanche, Deon; Jalkanen, Liisa

    2013-04-01

    counterparts. The urban environment also provides numerous opportunities. One example being the better use of weather and environmental predictions to proactively optimize the functioning of the urban environment in terms of the use of energy, goods and services. Another is the providing of air quality forecasting services to benefit the health of the population. To address the challenges and opportunities facing megacities and large urban complexes, WMO has established the Global Atmosphere Watch (GAW) Urban Research Meteorology and Environment (GURME). Air pollution questions in urban areas, in particular megacities, is the main focus, building observational and modelling capabilities in developing countries through pilot projects and transfer of scientific expertise. GURME contributes to improving capabilities to handle meteorological and related features of air pollution by addressing end-to-end aspects of air quality, linking observational capabilities with the needs of chemical weather prediction, with the goal of providing high quality air quality services. Using examples from around the world but with specific reference to Africa, the unique challenges and opportunities related to megacities and large urban complexes, as perceived by the World Meteorological Organization (WMO) are highlighted.

  10. Rethinking global health challenges: towards a 'global compact' for reducing the burden of chronic disease.

    Science.gov (United States)

    Magnusson, R S

    2009-03-01

    Chronic diseases, including cardiovascular disease, diabetes and cancer, are the leading cause of death and disability in both the developed and developing world (excluding sub-Saharan Africa). At present, the global framework for action on chronic disease is strongly 'World Health Organization (WHO)-centric', defined by two WHO initiatives: the WHO Framework Convention on Tobacco Control, and the Global Strategy on Diet, Physical Activity and Health. This paper explores the difficulties of developing a collective response to global health challenges, and draws out some implications for chronic disease. It highlights how political partnerships and improved governance structures, economic processes, and international laws and standards function as three, concurrent pathways for encouraging policy implementation at country level and for building collective commitment to address the transnational determinants of chronic disease. The paper evaluates WHO's initiatives on chronic disease in terms of these pathways, and makes the case for a global compact on chronic disease as a possible structure for advancing WHO's free-standing goal of reducing mortality from chronic diseases by an additional 2% between 2005 and 2015. Beneath this overarching structure, the paper argues that global agencies, donor governments and other global health stakeholders could achieve greater impact by coordinating their efforts within a series of semi-autonomous 'policy channels' or 'workstreams'. These workstreams - including trade and agriculture, consumer health issues and workplace health promotion - could act as focal points for international cooperation, drawing in a wider range of health stakeholders within their areas of comparative advantage.

  11. Infertility: Ongoing Global challenge of new millennium

    Directory of Open Access Journals (Sweden)

    Kantibhai Naranbhai Sonaliya

    2016-06-01

    Full Text Available Background: Infertility tends to be the global challenge even in the second decade of the new millennium. Especially in developing countries like India, it is still one the most lethal social evil responsible for a big proportion of cases of psychological disturbances including suicide. Again, recently, few conditions other than communicable or Non-communicable diseases are given place among the categories of significant public health problems like Road Traffic Accidents, Burns, Poisoning, drowning and few more. But, for developing countries like India, the list is incomplete without inclusion of Infertility (there may be several others also. In public health, tuberculosis, leprosy and some other diseases are considered social diseases which produce social stigma for the patients and/or his family members.1 In same manner, Infertility is an important cause of social stigmatization since centuries for a couple suffering from, especially for woman involved. During a transitory phase of industrialization and socio-economic development, the situation is changed a minute smidgen at urban areas of India but at rural parts, sub-urban or even at urban slums (mainly among pockets of recent migrants the situation is as same as a few hundred years ago. A female of no religion, caste, social status or higher level of education are barred from some stringent mores related to infertility. Infertile females are still not allowed to take part in so many religious or social ceremonies; on the contrary, they have to face more harassment including domestic violence than their counterparts, who have given birth to the child. Due to social, psychological, economic disturbances, they are forced to take multiple sorts of treatments including religious quacks. So many infertile women are exploited physically and economically also in such weird ways of treatment to gain a pregnancy.

  12. The Mountain Invasion Research Network (MIREN): Linking Local and Global Scales for Addressing an Ecological Consequence of Global Change

    Science.gov (United States)

    Christoph Kueffer; Curtis Daehler; Hansjörg Dietz; Keith McDougall; Catherine Parks; Aníbal Pauchard; Lisa Rew

    2014-01-01

    Many modern environmental problems span vastly different spatial scales, from the management of local ecosystems to understanding globally interconnected processes, and addressing them through international policy. MIREN tackles one such “glocal” (global/local) environmental problem – plant invasions in mountains – through a transdisciplinary, multi-scale learning...

  13. HIV and Hepatitis Testing: Global Progress, Challenges, and Future Directions.

    Science.gov (United States)

    Easterbrook, Philippa; Johnson, Cheryl; Figueroa, Carmen; Baggaley, Rachel

    2016-01-01

    HIV infection and viral hepatitis due to HBV and HCV infection are major causes of chronic disease worldwide, and share some common routes of transmission, epidemiology, initial barriers faced in treatment access, and in strategies for a global public health response. Testing and diagnosis of HIV, HBV, and HCV infection is the gateway for access to both care and treatment and prevention services, and crucial for an effective HIV and hepatitis epidemic response. In this review article, we first summarize the common goals and guiding principles in a public health approach to HIV and hepatitis testing. We summarize the impressive global progress in HIV testing scale-up and evolution of approaches, with expansion of provider-initiated testing and counseling in clinical settings (particularly antenatal and tuberculosis clinics), the introduction of more community based testing services, and use of rapid diagnostic tests enabling provision of same-day test results. However, 46% of all people living with HIV are still unaware of their serostatus, and many continue to be diagnosed and start antiretroviral therapy late. As testing and treatment scale-up accelerates for an "treat all" approach, other challenges to address include how to better focus testing and reach those yet undiagnosed and most at risk, especially key populations, men, adolescents, and children. We summarize future directions in HIV testing to speed scale-up and close gaps that are addressed in the WHO 2015 consolidated HIV testing guidelines. In contrast to HIV, action in hepatitis testing and treatment has been fragmented and limited to a few countries, and there remains a large burden of undiagnosed cases globally. We summarize key challenges in the hepatitis testing response, including lack of simple, reliable, and low-cost diagnostic tests, laboratory capacity, and testing facilities; inadequate data to guide country specific hepatitis testing approaches and who to screen; stigmatization and social

  14. Biological approaches for addressing the grand challenge of providing access to clean drinking water.

    Science.gov (United States)

    Riley, Mark R; Gerba, Charles P; Elimelech, Menachem

    2011-03-31

    The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms.

  15. Biological approaches for addressing the grand challenge of providing access to clean drinking water

    Science.gov (United States)

    2011-01-01

    The U.S. National Academy of Engineering (NAE) recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF). Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms. PMID:21453515

  16. Biological approaches for addressing the grand challenge of providing access to clean drinking water

    Directory of Open Access Journals (Sweden)

    Gerba Charles P

    2011-03-01

    Full Text Available Abstract The U.S. National Academy of Engineering (NAE recently published a document presenting "Grand Challenges for Engineering". This list was proposed by leading engineers and scientists from around the world at the request of the U.S. National Science Foundation (NSF. Fourteen topics were selected for these grand challenges, and at least seven can be addressed using the tools and methods of biological engineering. Here we describe how biological engineers can address the challenge of providing access to clean drinking water. This issue must be addressed in part by removing or inactivating microbial and chemical contaminants in order to properly deliver water safe for human consumption. Despite many advances in technologies this challenge is expanding due to increased pressure on fresh water supplies and to new opportunities for growth of potentially pathogenic organisms.

  17. ETHICAL CHALLENGES OF THE GLOBALIZATION PROCESS

    OpenAIRE

    Radenko Maric; Branko Balj

    2009-01-01

    Whereas roots of globalization are far reaching, it is primarily a modern age phenomenon. Modern business operation and the world economy are characterized by domination of multinational corporations, strong presence of the government in economy and the long-term tendency towards globalization in manufacturing, trading and consumption in the world. Containing both risks and opportunities, globalization is a problem of manifold nature. For some it means regression and falling into “neocolonial...

  18. The Global Challenge for Accounting Education

    Science.gov (United States)

    Helliar, Christine

    2013-01-01

    Accounting and education are both global phenomena, and there is thus an argument that accounting education should be consistent and comparable across the globe. However, accounting, and accounting education are all socially constructed and globally they have been influenced by their historical, social, economic, political and cultural contexts.…

  19. The Global Challenge for Accounting Education

    Science.gov (United States)

    Helliar, Christine

    2013-01-01

    Accounting and education are both global phenomena, and there is thus an argument that accounting education should be consistent and comparable across the globe. However, accounting, and accounting education are all socially constructed and globally they have been influenced by their historical, social, economic, political and cultural contexts.…

  20. Ethical challenges of the globalization process

    Directory of Open Access Journals (Sweden)

    Radenko Maric

    2009-12-01

    Full Text Available Whereas roots of globalization are far reaching, it is primarily a modern age phenomenon. Modern business operation and the world economy are characterized by domination of multinational corporations, strong presence of the government in economy and the long-term tendency towards globalization in manufacturing, trading and consumption in the world. Containing both risks and opportunities, globalization is a problem of manifold nature. For some it means regression and falling into “neocolonialism”, the others glorify it. It is logical to ask the following questions: What are the consequences of globalization for governments, nations, companies and individuals? What are the business, social and ethical issues it causes? In one word, is it possible to be ethical, to avoid and correct “bad” and keep “good” consequences of total phenomena as the globalization, and whether it is rewarding in the increasing market competition?

  1. The Challenge of Global Poliomyelitis Eradication.

    Science.gov (United States)

    Garon, Julie R; Cochi, Stephen L; Orenstein, Walter A

    2015-12-01

    In the United States during the 1950's, polio was on the forefront of every provider and caregiver's mind. Today, most providers in the United States have never seen a case. The Global Polio Eradication Initiative (GPEI), which began in 1988 has reduced the number of cases by over 99%. The world is closer to achieving global eradication of polio than ever before but as long as poliovirus circulates anywhere in the world, every country is vulnerable. The global community can support the polio eradication effort through continued vaccination, surveillance, enforcing travel regulations and contributing financial support, partnerships and advocacy.

  2. The Cloud Adoption Toolkit: Addressing the Challenges of Cloud Adoption in Enterprise

    CERN Document Server

    Greenwood, David; Smith, James; Sommerville, Ian

    2010-01-01

    Cloud computing promises a radical shift in the provisioning of computing resource within enterprise. This paper: i) describes the challenges that decision-makers face when attempting to determine the feasibility of the adoption of cloud computing in their organisations; ii) illustrates a lack of existing work to address the feasibility challenges of cloud adoption in enterprise; iii) introduces the Cloud Adoption Toolkit that provides a framework to support decision-makers in identifying their concerns, and matching these concerns to appropriate tools/techniques that can be used to address them. The paper adopts a position paper methodology such that case study evidence is provided, where available, to support claims. We conclude that the Cloud Adoption Toolkit, whilst still under development, shows signs that it is a useful tool for decision-makers as it helps address the feasibility challenges of cloud adoption in enterprise.

  3. Globalization, Consumerism and the Challenge of Sustainable ...

    African Journals Online (AJOL)

    Nneka Umera-Okeke

    oxymoron of globalization more evident than in economic relations between ... the industrialized West and Asian countries such as Japan, Korea, China and India. ..... music, media, movies, marketing, fashion, cuisine, etc. and as the dynamics ...

  4. The global change challenge: a regional perspective

    CSIR Research Space (South Africa)

    Engelbrecht, F

    2012-10-01

    Full Text Available In this presentation the author presents the most recent projections of future climate change over southern Africa, based on high-resolution downscalings of the global model projections of Assessment Reports Four and Five of the Intergovernmental...

  5. From Labour to Work: The Global Challenge.

    Science.gov (United States)

    Standing, Guy

    1999-01-01

    Discusses the shift from rights of labor through the right to labor, to the duty to labor and the changes that have resulted. Suggests that the result is global awareness of pervasive social and economic insecurity. (Author/JOW)

  6. Research and Technology Development Activities to Address the DOE-EM Environmental Mercury Challenge

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Eric M [ORNL; Peterson, Mark J [ORNL

    2017-01-01

    Human activities have altered trace metal distributions globally. This is especially true for the trace metal mercury (Hg), a pervasive global pollutant that can be methylated to form highly toxic methylmercury (MeHg), which bioaccumulates in aquatic food webs, endangering humans and other biota. Currently there are more than 3,000 mercury-contaminated sites identified worldwide and the United Nations Environment Programme has recently highlighted the risk of this contamination to human health [1, 2]. The Oak Ridge Reservation (ORR) represents an example of one of these mercury-contaminated sites. Unlike other contaminants metals, radionuclides, and organic solvents that impact the Department of Energy Office of Environmental Management (DOE-EM) cleanup program at the ORR and other DOE sites, mercury has several unique characteristics that make environmental remediation of the Y-12 National Security Complex one of the most formidable challenges ever encountered. These distinctive physicochemical properties for mercury include the following: it is a liquid at ambient temperature and pressure; it is the only metal that biomagnifies; and it is the only contaminant transported as a cation, as a dissolved or gaseous elemental metal (similar to an organic solvent), or as both a cation and a dissolved or gaseous elemental metal under environmental conditions. Because of these complexities, implementing cost effective and sustainable solutions that reduce mercury flux from various primary and secondary contamination sources will require linking basic science understanding and applied research advancements into Oak Ridge Office of Environmental Management s (OREM) cleanup process. Currently, DOE is investing in mercury-related research through a variety of programs, including the Office of Science sponsored Critical Interfaces Science Focus Area, EM headquarters sponsored Applied Field Research Initiative, OREM-sponsored Lower East Fork Poplar Creek (LEFPC) Mercury

  7. Global networks for invasion science: benefits, challenges and guidelines

    DEFF Research Database (Denmark)

    Packer, Jasmin G.; Meyerson, Laura A.; Richardson, David M.

    2017-01-01

    . Questions on the role of biogeography (e.g., how does biogeography influence ecosystem susceptibility, resistance and resilience against invasion?) have the greatest potential to address this goal by increasing our capacity to understand and accurately predict invasions at local, continental and global...... scales. This paper proposes a framework for the development of ‘Global Networks for Invasion Science’ to help generate approaches to address these critical and fundamentally biogeographic questions. We define global networks on the basis of their focus on research questions at the global scale......, collection of primary data, use of standardized protocols and metrics, and commitment to long-term global data. Global networks are critical for the future of invasion science because of their potential to extend beyond the capacity of individual partners to identify global priorities for research agendas...

  8. Challenges to professionalism: Social accountability and global environmental change.

    Science.gov (United States)

    Pearson, David; Walpole, Sarah; Barna, Stefi

    2015-01-01

    This article explores the concept of professionalism as it relates to social change and social accountability, and expands on them in the light of global environmental changes. Professionalism in medicine includes concepts of altruism, service, professional knowledge, self-regulation and autonomy. Current dialogues around social accountability suggest that medical schools should re-orientate their strategy and desired education, research and service outcomes to the health needs of the communities they serve.This article addresses the following questions: • How do we reconcile ideas of medical professionalism with the demands of creating a more equal, just, sustainable and socially inclusive society? • What new challenges do or will we face in relation to environmental degradation, biodiversity loss, ecosystem health and climate change? • How can medical schools best teach social and environmental responsiveness within a framework of professionalism? • How do medical schools ensure that tomorrow's doctors possess the knowledge, skills and attitude to adapt to the challenges they will face in future roles?We offer ideas about why and how medical educators can change, recommendations to strengthen the teaching of professionalism and social accountability and suggestions about the contribution of an emerging concept, that of "environmental accountability".

  9. Globalization vs. localization: global food challenges and local sollutions

    NARCIS (Netherlands)

    Quaye, W.; Jongerden, J.P.; Essegbey, G.; Ruivenkamp, G.T.P.

    2010-01-01

    The objective of this study was to examine the effect of global-local interactions on food production and consumption in Ghana, and identify possible local solutions. Primary data were collected using a combination of quantitative-qualitative methods, which included focus group discussions and

  10. GLOBAL CLIMATE CHANGE--THE TECHNOLOGY CHALLENGE

    Science.gov (United States)

    Anthropogenic emissions of greenhouse gases, such as carbon dioxide, have led to increasing atmospheric concentrations which are at least partly responsible for the roughly 0.7% degree C global warming earth has experienced since the industrial revolution. With industrial activit...

  11. [Justice challenges of pharmaceutical industry global research].

    Science.gov (United States)

    Páez Moreno, Ricardo

    2010-01-01

    International research projects sponsored by the pharmaceutical industry are a recent modality of biomedical research, which is driven by interests that are not only scientific, but also commercial. This combination of interests is one of the natural consequences of globalization, which has brought unquestionable benefits for the world, but has also created a wider gap between the wealthy and the poor. Given that globalization has been led by the the world's leading economies, the level of injustice in the world has increased, often to the favor of the already wealthy. Globalization has a well-established dynamics, whose main characteristic is domain over the following: technological innovation, the organization of the production of goods and services, human needs, and consumption. International biomedical research fits well in this dynamics, and the result is often a poor distribution of benefits, added to a loss of scientific integrity for the sake of commercial interests. This phenomenon raises many ethical questions and it demands a reflection from different bioethical points of view, particularly an economic ethics and a global justice.

  12. Defense Weather Satellites: DOD Faces Acquisition Challenges for Addressing Capability Needs

    Science.gov (United States)

    2016-07-07

    design . Our work on the NPOESS program has shown that without clear lines of authority, conflicts between satellite users hampered decisions, such as for...DEFENSE WEATHER SATELLITES DOD Faces Acquisition Challenges for Addressing Capability Needs Statement of Cristina T...Environment, Committee on Science, Space, and Technology, House of Representatives July 2016 DEFENSE WEATHER SATELLITES DOD Faces Acquisition

  13. Addressing Challenging Behaviors in Head Start: A Closer Look at Program Policies and Procedures

    Science.gov (United States)

    Quesenberry, Amanda C.; Hemmeter, Mary Louise; Ostrosky, Michaelene M.

    2011-01-01

    In this study, Head Start policies and procedures related to child guidance and addressing challenging behaviors were examined. Data were gathered from six Head Start programs in the Midwest, through interviews and document analysis. The findings provide a glimpse into how Head Start programs support children's social and emotional competence and…

  14. Addressing the Challenges Encountered during a Developmental Evaluation: Implications for Evaluation Practice

    Science.gov (United States)

    Poth, Cheryl-Anne; Pinto, Dorothy; Howery, Kathy

    2011-01-01

    This article describes three challenges encountered during a developmental evaluation and explains how these were addressed from the evaluators' perspective. The evaluation was conducted to support the implementation of a three-year educational technology leadership project funded by the Alberta provincial government. The developmental evaluation…

  15. Addressing the diagnostic and therapeutic challenges in inheritable arrhythmia syndromes: with emphasis on the pediatric population

    NARCIS (Netherlands)

    Chockalingam, P.

    2012-01-01

    This thesis addresses some of the most pressing issues and challenges in the management of congenital long QT syndrome and loss-of-function sodium channelopathies, with a special focus on the pediatric population. With inheritable arrhythmia syndromes emerging as an important piece in the puzzle of

  16. Grid-Integrated Distributed Solar: Addressing Challenges for Operations and Planning, Greening the Grid

    Energy Technology Data Exchange (ETDEWEB)

    Coddington, Michael; Miller, Mackay; Katz, Jessica

    2016-03-01

    Greening the Grid provides technical assistance to energy system planners, regulators, and grid operators to overcome challenges associated with integrating variable renewable energy into the grid. This document introduces a brief overview of common technical impacts of PV on distribution systems and operations, as well as emerging strategies for successfully addressing some of the priority issues.

  17. DIRECTIONS AND CHALLENGES IN GLOBAL AGRICULTURE

    Directory of Open Access Journals (Sweden)

    Daniela POPA

    2013-01-01

    Full Text Available The development of global agricultural market has been at the forefront of professional studies. Expert opinions have quite differing views as to whether the world’s food production will be able to supply the huge demand of growing population. This scientific paper provides a general overview of global agricultural directions, including views on whether agricultural productivity increases will be able to keep with food demand increases and price trends. The scientific paper has focused on the present state of the agricultural market and on the analysis of the key factors defining the tasks of the agricultural sector in the near future, with a special attention to the case of Republic of Moldova.

  18. Migration and Globalization: Challenges and Perspectives

    OpenAIRE

    Mariana Bălan

    2017-01-01

    The globalization of modern world stimulated marked increases in the migration to locations both near and far supported by several factors either of economic, social or environmental nature or by political instability and the development of some sophisticated, modern transport systems and networks that facilitated easier, cheaper and quicker movement of individuals than in any other moment in mankind’s history. Thus, the number of international migrants reached 244 million in 2015 on increase...

  19. Global Citizens: Social Movements and the Challenge of Globalization

    OpenAIRE

    Mayo, Marjorie C.

    2005-01-01

    The dawn of the twenty first century has been accompanied by an upsurge of anti-capitalist campaigning, challenging the very basis of the New World Economic order. This book sets out to explore the lessons from these experiences of social mobilization. How can non-governmental organizations, community based organizations and the labor and trade union movement develop effective campaigning alliances--without becoming institutionalized and incorporated themselves? How can they balance immediate...

  20. Ergonomics and sustainability – challenges from global supply chains

    DEFF Research Database (Denmark)

    Hasle, Peter; Jensen, Per Langaa

    2012-01-01

    The development of globalised supply chains is a major challenge for sustainability. For several years, there has been discussion within the profession whether and how ergonomics and human factors can play a role. Based on our research, we have identified five major challenges from global supply...... sustainability. Starting from such a basis, the next step would be to find ways for the ergonomics and human factors community to create international collaboration which can impact specific global supply chains....

  1. Tool for evaluating research implementation challenges: a sense-making protocol for addressing implementation challenges in complex research settings.

    Science.gov (United States)

    Simpson, Kelly M; Porter, Kristie; McConnell, Eleanor S; Colón-Emeric, Cathleen; Daily, Kathryn A; Stalzer, Alyson; Anderson, Ruth A

    2013-01-02

    Many challenges arise in complex organizational interventions that threaten research integrity. This article describes a Tool for Evaluating Research Implementation Challenges (TECH), developed using a complexity science framework to assist research teams in assessing and managing these challenges. During the implementation of a multi-site, randomized controlled trial (RCT) of organizational interventions to reduce resident falls in eight nursing homes, we inductively developed, and later codified the TECH. The TECH was developed through processes that emerged from interactions among research team members and nursing home staff participants, including a purposive use of complexity science principles. The TECH provided a structure to assess challenges systematically, consider their potential impact on intervention feasibility and fidelity, and determine actions to take. We codified the process into an algorithm that can be adopted or adapted for other research projects. We present selected examples of the use of the TECH that are relevant to many complex interventions. Complexity theory provides a useful lens through which research procedures can be developed to address implementation challenges that emerge from complex organizations and research designs. Sense-making is a group process in which diverse members interpret challenges when available information is ambiguous; the groups' interpretations provide cues for taking action. Sense-making facilitates the creation of safe environments for generating innovative solutions that balance research integrity and practical issues. The challenges encountered during implementation of complex interventions are often unpredictable; however, adoption of a systematic process will allow investigators to address them in a consistent yet flexible manner, protecting fidelity. Research integrity is also protected by allowing for appropriate adaptations to intervention protocols that preserve the feasibility of 'real world

  2. Regional initiatives to address the challenges of tuberculosis in children: perspectives from the Asia-Pacific region

    Directory of Open Access Journals (Sweden)

    Stephen M. Graham

    2015-03-01

    Full Text Available Increasing attention is being given to the challenges of management and prevention of tuberculosis in children and adolescents. There have been a number of recent important milestones achieved at the global level to address this previously neglected disease. There is now a need to increase activities and build partnerships at the regional and national levels in order to address the wide policy-practice gaps for implementation, and to take the key steps outlined in the Roadmap for Child Tuberculosis published in 2013. In this article, we provide the rationale and suggest strategies illustrated with examples to improve diagnosis, management, outcomes and prevention for children with tuberculosis in the Asia-Pacific region, with an emphasis on the need for greatly improved recording and reporting. Effective collaboration with community engagement between the child health sector, the National Tuberculosis control Programmes, community-based services and the communities themselves are essential.

  3. Challenges to the Common Good in the Age of Globalism.

    Science.gov (United States)

    Barber, Benjamin R.

    2000-01-01

    Explains that the challenge for the next millennium is preserving and securing the common good against the forces associated with globalization. Discusses globalization in detail, the privatization of public power, the commercialization of what is privatized, and the infantilization and homogeneity of consumers. (CMK)

  4. Modern trends and challenges of development of global aluminum industry

    Directory of Open Access Journals (Sweden)

    M. N. Dudin

    2017-12-01

    Full Text Available This article overviews complex study into modern trends and challenges of development of global aluminum industry. Dynamics, structure, and segmentation of global aluminum market are discussed in terms of systematic analysis. On this basis strategic map of the industry has been plotted and five forces of competition on global aluminum market have been determined which will influence directly on functioning and development of aluminum producing companies.

  5. The role and challenges of the food industry in addressing chronic disease

    Directory of Open Access Journals (Sweden)

    Kehoe Stephen

    2010-05-01

    Full Text Available Summary Increasingly, food companies play an important role in stemming the rising burden of nutrition-related chronic diseases. Concrete actions taken by these companies include global public commitments to address food reformulation, consumer information, responsible marketing, promotion of healthy lifestyles, and public-private partnerships. These actions are reviewed together with eleven specific PepsiCo goals and commitments that address products, the marketplace, and communities at large. Interim progress on these goals and commitments are discussed as well as constraints hampering faster progress. Further disease prevention depends on increasing implementation of private-public initiatives.

  6. The role and challenges of the food industry in addressing chronic disease.

    Science.gov (United States)

    Yach, Derek; Khan, Mehmood; Bradley, Dondeena; Hargrove, Rob; Kehoe, Stephen; Mensah, George

    2010-05-28

    Increasingly, food companies play an important role in stemming the rising burden of nutrition-related chronic diseases. Concrete actions taken by these companies include global public commitments to address food reformulation, consumer information, responsible marketing, promotion of healthy lifestyles, and public-private partnerships. These actions are reviewed together with eleven specific PepsiCo goals and commitments that address products, the marketplace, and communities at large. Interim progress on these goals and commitments are discussed as well as constraints hampering faster progress. Further disease prevention depends on increasing implementation of private-public initiatives.

  7. Rebalancing brain drain: exploring resource reallocation to address health worker migration and promote global health.

    Science.gov (United States)

    Mackey, Timothy Ken; Liang, Bryan Albert

    2012-09-01

    Global public health is threatened by an imbalance in health worker migration from resource-poor countries to developed countries. This "brain drain" results in health workforce shortages, health system weakening, and economic loss and waste, threatening the well-being of vulnerable populations and effectiveness of global health interventions. Current structural imbalances in resource allocation and global incentive structures have resulted in 57 countries identified by WHO as having a "critical shortage" of health workers. Yet current efforts to strengthen domestic health systems have fallen short in addressing this issue. Instead, global solutions should focus on sustainable forms of equitable resource sharing. This can be accomplished by adoption of mandatory global resource and staff-sharing programs in conjunction with implementation of state-based health services corps.

  8. Meeting the Global Challenge through Production Offshoring

    DEFF Research Database (Denmark)

    Slepniov, Dmitrij

    and policy makers. Building on ground that is already well trodden within the academic literature, the study searches for novel multidisciplinary explanations about how the production function can be organised by lead firms on a global scale and, more importantly, what the strategic implications...... to the current debates about how these firms could assert themselves in a world of far-reaching transformation. As the title of the study suggests, this contribution is made through focusing the discussion upon production offshoring, which is currently commanding attention of so many practitioners, academics...... of this process are. While the study concentrates on the production function, the implications of the discussion stretch much wider; the study also reveals implications for other functions and the company as a whole, as well as it points towards broader societal implications. The study employs a qualitative...

  9. Global challenges in integrated coastal zone management

    DEFF Research Database (Denmark)

    place in Arendal, Norway between 3-7 July 2011. The main objective of the Symposium was to present current knowledge and to address issues on advice and management related to the coastal zone. The major themes of papers included in this book are: Coastal habitats and ecosystem services Adaptation...... integration of data and information in policy and management, combining expertise from nature and social science, to reach a balanced and sustainable development of the coastal zone. This important book comprises the proceedings of The International Symposium on Integrated Coastal Zone Management, which took....../mitigation to change in coastal systems Coastal governance Linking science and management Comprising a huge wealth of information, this timely and well-edited volume is essential reading for all those involved in coastal zone management around the globe. All libraries in research establishments and universities where...

  10. Climate Change - Global Risks, Challenges & Decisions

    DEFF Research Database (Denmark)

    Richardson, Katherine; Steffen, Will; Schellnhuber, Hans J.

    negotiations is the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC), published in 2007. The IPCC report has already been instrumental in increasing both public and political awareness of the societal risks associated with unchecked emission of greenhouse gases. Since...... and environment, and the many tools and approaches available to deal effectively with the challenge of climate change. The report has been produced by a writing team comprised of members of the Scientific Steering Committee for the IARU Congress and individuals invited to give the writing team academic...... of this volume. The writing team has, in addition to presentations at the Congress, drawn upon recent publications in the scientific literature to create this synthesis. This report has been critically reviewed by representatives of the Earth System Science Partnership (ESSP), by the parallel session chairs...

  11. Climate Change - Global Risks, Challenges & Decisions

    DEFF Research Database (Denmark)

    Richardson, Katherine; Steffen, Will; Schellnhuber, Hans J.;

    and environment, and the many tools and approaches available to deal effectively with the challenge of climate change. The report has been produced by a writing team comprised of members of the Scientific Steering Committee for the IARU Congress and individuals invited to give the writing team academic...... and geographic breadth. It is based on the 16 plenary talks given at the Congress as well as input from over 80 chairs and cochairs of the 58 parallel sessions held at the Congress. The names of the plenary speakers and the chairs and co-chairs of the parallel sessions can be found on the inside cover...... of this volume. The writing team has, in addition to presentations at the Congress, drawn upon recent publications in the scientific literature to create this synthesis. This report has been critically reviewed by representatives of the Earth System Science Partnership (ESSP), by the parallel session chairs...

  12. Addressing mental health challenges facing the "Next America": A call for culture change.

    Science.gov (United States)

    McLeigh, Jill D; Melton, Gary B

    2015-09-01

    Provides an editorial addressing future mental health challenges. The articles in this issue highlight the need to create environments conducive to promoting the well-being of future generations. The articles build on symposia held by the American Orthopsychiatric Association in 2015, which focused on the effects on well-being of changing sociodemographics and labor market trends. Included in these pages are articles that lay out some of the challenges young people today face and strategies for helping them transition to adulthood successfully. (c) 2015 APA, all rights reserved).

  13. A novel addressing scheme for PMIPv6 based global IP-WSNs.

    Science.gov (United States)

    Islam, Md Motaharul; Huh, Eui-Nam

    2011-01-01

    IP based Wireless Sensor Networks (IP-WSNs) are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

  14. A Novel Addressing Scheme for PMIPv6 Based Global IP-WSNs

    Directory of Open Access Journals (Sweden)

    Md. Motaharul Islam

    2011-08-01

    Full Text Available IP based Wireless Sensor Networks (IP-WSNs are being used in healthcare, home automation, industrial control and agricultural monitoring. In most of these applications global addressing of individual IP-WSN nodes and layer-three routing for mobility enabled IP-WSN with special attention to reliability, energy efficiency and end to end delay minimization are a few of the major issues to be addressed. Most of the routing protocols in WSN are based on layer-two approaches. For reliability and end to end communication enhancement the necessity of layer-three routing for IP-WSNs is generating significant attention among the research community, but due to the hurdle of maintaining routing state and other communication overhead, it was not possible to introduce a layer-three routing protocol for IP-WSNs. To address this issue we propose in this paper a global addressing scheme and layer-three based hierarchical routing protocol. The proposed addressing and routing approach focuses on all the above mentioned issues. Simulation results show that the proposed addressing and routing approach significantly enhances the reliability, energy efficiency and end to end delay minimization. We also present architecture, message formats and different routing scenarios in this paper.

  15. Global Health Governance Challenges 2016 – Are We Ready?

    OpenAIRE

    Ilona Kickbusch

    2016-01-01

    The year 2016 could turn out to be a turning point for global health, new political realities and global insecurities will test governance and financing mechanisms in relation to both people and planet. But most importantly political factors such as the global power shift and “the rise of the rest” will define the future of global health. A new mix of health inequity and security challenges has emerged and the 2015 humanitarian and health crises have shown the limits of existing s...

  16. Challenges Addressing Unmet Need for Contraception: Voices of Family Planning Service Providers in Rural Tanzania.

    Science.gov (United States)

    Baraka, Jitihada; Rusibamayila, Asinath; Kalolella, Admirabilis; Baynes, Colin

    2015-12-01

    Provider perspectives have been overlooked in efforts to address the challenges of unmet need for family planning (FP). This qualitative study was undertaken in Tanzania, using 22 key informant interviews and 4 focus group discussions. The research documents perceptions of healthcare managers and providers in a rural district on the barriers to meeting latent demand for contraception. Social-ecological theory is used to interpret the findings, illustrating how service capability is determined by the social, structural and organizational environment. Providers' efforts to address unmet need for FP services are constrained by unstable reproductive preferences, low educational attainment, and misconceptions about contraceptive side effects. Societal and organizational factors--such as gender dynamics, economic conditions, religious and cultural norms, and supply chain bottlenecks, respectively--also contribute to an adverse environment for meeting needs for care. Challenges that healthcare providers face interact and produce an effect which hinders efforts to address unmet need. Interventions to address this are not sufficient unless the supply of services is combined with systems strengthening and social engagement strategies in a way that reflects the multi-layered, social institutional problems.

  17. Transporting integrated primary care to the private sector: addressing the business challenges.

    Science.gov (United States)

    Margolis, Ronald B; Pollard, C Alec; Niemiec, Ryan

    2013-09-01

    The primary care literature provides some useful information and several project examples for clinicians attempting to develop an integrated care practice, but prior discussion has been based largely on projects developed in government-funded or HMO systems. The current paper focuses on the business challenges of establishing an integrated care practice in a private, fee-for-service setting. Despite increasing commitment to the concept of the medical home, which embraces behavioral health care, physicians in the private sector remain cautious about proposed practice changes such as integrated care. There are additional obstacles that can impede successful implementation of integrated primary care in the private sector. The authors identify five major challenges and suggest potential strategies to address these challenges, drawing, in part, on their experience with a 4-year integrated primary care demonstration project.

  18. Globalizing Compassion, Photography, and the Challenge of Terror

    OpenAIRE

    Dorfman, Ariel

    2007-01-01

    In his article, "Globalizing Compassion, Photography, and the Challenge of Terror," Ariel Dorfman reflects on the use of photography to make global violence visible and to mourn the losses caused by acts of terror. Dorfman draws on events that range from the attacks on the World Trade Center to Pinochet's dictatorship to other similar atrocities and he shows that, while these events always feel singular in the moment, they are best understood comparatively. At the core of the paper is a centr...

  19. ASCO's Community Research Forum: addressing challenges of community-based research from the grass roots.

    Science.gov (United States)

    Robert, Nicholas; Lilenbaum, Rogerio; Hurley, Patricia

    2014-01-01

    ASCO's Community Research Forum is a solution-oriented venue for community research sites to overcome barriers to conducting clinical trials. The key objectives of the Forum are to (1) convene community-based researchers to identify challenges to conducting research that ASCO can address, (2) develop solution-oriented projects to address these challenges to facilitate clinical trial participation in community research settings, and (3) shape ASCO programs and policies to support members engaged in community research. The Community Research Forum holds an annual in-person meeting that convenes physician investigators, research administrators, research nurses, and clinical research associates from community-based research programs and practices. To meet identified needs, the Community Research Forum has developed the ASCO Clinical Trial Workload Assessment Tool and the ASCO Research Program Quality Assessment Tool. Both of these tools will be available to the public in 2014. The Forum is currently exploring the concept and potential metrics of a research certification program to formally assess community-based research programs, and to identify gaps and areas to improve the program in order to meet quality standards. The Community Research Forum's website aims to serve as a go-to resource for community-based physician investigators and research staff. The Community Research Forum will continue to provide a forum for community-based researchers to network, share challenges, and develop initiatives that provide solutions and facilitate the conduct of clinical trials.

  20. Moving beyond regression techniques in cardiovascular risk prediction: applying machine learning to address analytic challenges.

    Science.gov (United States)

    Goldstein, Benjamin A; Navar, Ann Marie; Carter, Rickey E

    2016-07-19

    Risk prediction plays an important role in clinical cardiology research. Traditionally, most risk models have been based on regression models. While useful and robust, these statistical methods are limited to using a small number of predictors which operate in the same way on everyone, and uniformly throughout their range. The purpose of this review is to illustrate the use of machine-learning methods for development of risk prediction models. Typically presented as black box approaches, most machine-learning methods are aimed at solving particular challenges that arise in data analysis that are not well addressed by typical regression approaches. To illustrate these challenges, as well as how different methods can address them, we consider trying to predicting mortality after diagnosis of acute myocardial infarction. We use data derived from our institution's electronic health record and abstract data on 13 regularly measured laboratory markers. We walk through different challenges that arise in modelling these data and then introduce different machine-learning approaches. Finally, we discuss general issues in the application of machine-learning methods including tuning parameters, loss functions, variable importance, and missing data. Overall, this review serves as an introduction for those working on risk modelling to approach the diffuse field of machine learning.

  1. Capacity building for global nursing leaders: challenges and experiences.

    Science.gov (United States)

    Shin, S; Han, J; Cha, C

    2016-12-01

    The aim of this article is to describe our experience in operating a capacity-building programme, the Korea International Cooperation Project, for global nursing leaders from developing countries, held during the International Council of Nurses (ICN) Conference in 2015 in Seoul, Korea. Globalization points to the importance of global leadership among nursing leaders. In accordance with the theme of 'Global Citizen, Global Nursing' at the ICN conference in 2015, a capacity-building programme for nursing leaders of developing countries was implemented. The global nursing leadership programme shared experiences during the preparation and operation of the conference. To prepare the programme, this paper describes selecting participants, working with invitation lists from 30 countries, and recruiting and training volunteers. The operation of the programme, orientation, organizing tailored programmes for participant groups, addressing unexpected issues and evaluating the programme are described. ICN could implement capacity-building programmes for nursing leaders of developing countries during its ICN conference for the nursing society. A programme tailored for each continent with similar sociocultural backgrounds and health issues would provide chances for collaboration and networking. A policy to compile global nursing indicators should be developed. This would allow nursing leaders to learn about the strengths and weaknesses of global nursing and provide evidence for collaboration. The programme was successful in introducing and broadening global perspectives of participants on health and education as well as building a network among leaders and next-generation leaders in participating countries for future cooperation and collaboration. © 2016 International Council of Nurses.

  2. Addressing water challenges on the North China Plain with hydroeconomic optimization

    DEFF Research Database (Denmark)

    Martinsen, Grith; Davidsen, Claus; Bauer-Gottwein, Peter

    With its diverse environment and large population, China is facing water resource challenges, both in terms of quantity and quality. The North China Plain (NCP) is one of the world’s most densely populated areas and one of the highly water stressed regions of China. It counts for 15% of the Chinese...... GDP, from both industry and agriculture. The high water demand for especially irrigation has caused decade long groundwater depletion, ecosystem deterioration and high pollution loads in the region. To alleviate the water crisis of Northern China the South-North Water Transfer Project has been...... constructed. However, the project alone cannot solve the NCP’s water crisis. A hydroeconomic optimization model has been developed for the NCP system. The model area represents the administrative area of the Hai River Commission. The challenges addressed are the spatio-temporal distribution of costs...

  3. Addressing the challenges for sustainable production of algal biofuels: II. Harvesting and conversion to biofuels.

    Science.gov (United States)

    Abdelaziz, Ahmed E M; Leite, Gustavo B; Hallenbeck, Patrick C

    2013-01-01

    In order to ensure the sustainability of algal biofuel production, a number of issues need to be addressed. Previously, we reviewed some of the questions in this area involving algal species and the important challenges of nutrient supply and how these might be met. Here, we take up issues involving harvesting and the conversion ofbiomass to biofuels. Advances in both these areas are required if these third-generation fuels are to have a sufficiently high net energy ratio and a sustainable footprint. A variety of harvesting technologies are under investigation and recent studies in this area are presented and discussed. A number of different energy uses are available for algal biomass, each with their own advantages as well as challenges in terms of efficiencies and yields. Recent advances in these areas are presented and some of the especially promising conversion processes are highlighted.

  4. Romanian spatial planning research facing the challenges of globalizing sciences

    Directory of Open Access Journals (Sweden)

    Alexandru-Ionuţ Petrişor

    2018-03-01

    competitiveness, measured in terms of scientific yield and citations, primarily affects fields where articles and citations are not the traditional outputs, such as the humanities and social sciences in general and planning-related disciplines in particular. When discussing planning, it has to be stressed out that research has a merely societal value and is not aimed at developing products that can foster economic growth or delivering scientific articles that profoundly change the theoretical perspectives. Simply put, research in planning aims at increasing the safety and welfare of people. As a consequence, planning research topics have shifted from providing scientific grounds to regional development policies, to addressing research quality and social responsibility or producing research guidelines. This article looks at the particular case of Romanian planning research based on SCImago data, in an attempt to assess whether this field is able to meet these global challenges, especially after the consistent, albeit uneven, in terms of goal and pace, application of new research policies designed after joining the European Union, which were aimed at increasing its article output and its international visibility. The findings indicate that the numerical growth of articles and publications is spectacular in Romania for most fields, and even more so within the humanities, the social sciences and planning. However, the question remains whether this impressive growth is supported by an increase in quality. We have therefore left aside matters such as the globalization of authors, topics or citations. These aspects require a more in-depth research effort.

  5. Summary: Addressing the Interactional Challenges of Moving Collaborative Adaptive Management From Theory to Practice

    Directory of Open Access Journals (Sweden)

    Kathi K. Beratan

    2014-03-01

    Full Text Available Translating the attractive concept of collaborative adaptive management (CAM into practice has proven very difficult. The papers included in this Special Feature explore why this is true and suggest how the challenges might be addressed. This summary highlights common themes, major challenges, and implications for research and practice. Many of the included papers emphasize the central importance of collaboration and stakeholder engagement as a response to complexity and uncertainty. Collectively, the papers make the case that a lack of knowledge about how to manage the human dynamics of comanagement poses a major challenge to implementing CAM. Human activities are the primary drivers of system change in most natural resource management systems, so attention to human dynamics is essential for developing useful change hypotheses and leading indicators that can provide useful and timely feedback for adaptive management. Institutions need to evolve to support adaptive and collaborative management processes. This will require thoughtful design of CAM processes, along with commitment of sufficient time and resources. Implementation challenges should be considered as a major focus for research rather than as simply barriers to progress. More effective ways of capturing practitioners' experiential knowledge are required to improve the practice of CAM. This Special Feature suggests that the concept of a CAM practitioners' journal has promise, but realization of that promise will require careful attention to the needs of and constraints on practitioners.

  6. Poverty and the Multiple Stakeholder Challenge for Global Leaders

    Science.gov (United States)

    Reade, Carol; Todd, Anne Marie; Osland, Asbjorn; Osland, Joyce

    2008-01-01

    The article presents a case study in which business leaders deal with challenging problems related to poverty, involving multiple stakeholders. This emphasizes the importance of training prospective global leaders to manage stakeholder relationships and engage in stakeholder dialogue. The authors highlight the stakeholder role played by…

  7. Career challenges and opportunities in the global chemistry enterprise

    Science.gov (United States)

    This article serves as an overview of the various career challenges and opportunities faced by chemistry professionals in the 21st century in the global chemistry enterprise. One goal is to highlight a broad spectrum of career paths, including non-traditional careers, and to showcase examples of ch...

  8. Global networks for invasion science: benefits, challenges and guidelines

    DEFF Research Database (Denmark)

    Packer, Jasmin G.; Meyerson, Laura A.; Richardson, David M.;

    2016-01-01

    Much has been done to address the challenges of biological invasions, but fundamental questions (e.g., which species invade? Which habitats are invaded? How can invasions be effectively managed?) still need to be answered before the spread and impact of alien taxa can be effectively managed. Ques...

  9. Ergonomics and sustainability--challenges from global supply chains.

    Science.gov (United States)

    Hasle, Peter; Jensen, Per Langaa

    2012-01-01

    The development of globalised supply chains is a major challenge for sustainability. For several years, there has been discussion within the profession whether and how ergonomics and human factors can play a role. Based on our research, we have identified five major challenges from global supply chains especially related to the social aspects of sustainability: (1) criteria for social sustainability, (2) the role of key performance indicators in the management of supply chains, (3) the constant changes in supply chains, (4) the challenge in establishing participation, and (5) the development of agency and regulatory mechanisms. There are obviously no clear and simple solutions to these challenges. One possible avenue for progress might lie in acquiring a greater understanding of the challenges from global supply chains and developing a strategy which combines social and long-term business sustainability. Starting from such a basis, the next step would be to find ways for the ergonomics and human factors community to create international collaboration which can impact specific global supply chains.

  10. City leadership: At the heart of the global challenge

    Energy Technology Data Exchange (ETDEWEB)

    Oliver, P.A.

    2008-09-30

    The world's attention is now focused on cities, and for good reasons. From a global perspective cities have become the engines of economic prosperity. In 2007, the collective Gross Domestic Product (GDP) of the top 10 cities exceeded the total GDP of 162 countries combined, with Tokyo alone generating a larger GDP than Canada. Cities have become the centers of population. In 1900, only 10% of the world's population lived in cities, but by 2007 the urban population had reached 50%, and the estimate for 2050 is that 75% of the world's population, over 7 billion people, will be living in cities. In parallel, cities have become the centers of consumption. In 2006, cities accounted for approximately 67% of global primary energy demand, a concentration that is expected to rise to 75% by 2030. The corollary to this concentration of population and consumption is the concentration of activities that lead to climate change. Cities now acount for over 70% of global carbon dioxide (CO{sub 2}) emissions. Asia's cities are at the forefront of the global challenges of urbanization. While they are the location of many challenges, cities also present opportunities, particularly in finding solutions to the crucial global challenges of our time -- climate change, energy demand and water. Many of the world's greatest challenges, from environmental degradation to widening income gaps, are increasingly coming to be defined as urban challenges, given the rapid growth of cities. The author, who leads the World Economic Forum's SlimCity initiative, take a look at the options being explored by the public and private sectors.

  11. Global Health Governance Challenges 2016 - Are We Ready?

    Science.gov (United States)

    Kickbusch, Ilona

    2016-02-29

    The year 2016 could turn out to be a turning point for global health, new political realities and global insecurities will test governance and financing mechanisms in relation to both people and planet. But most importantly political factors such as the global power shift and "the rise of the rest" will define the future of global health. A new mix of health inequity and security challenges has emerged and the 2015 humanitarian and health crises have shown the limits of existing systems. The global health as well as the humanitarian system will have to prove their capacity to respond and reform. The challenge ahead is deeply political, especially for the rising political actors. They are confronted with the consequences of a model of development that has neglected sustainability and equity, and was built on their exploitation. Some direction has been given by the path breaking international conferences in 2015. Especially the agreement on the Sustainable Development Goals (SDGs) and the Paris agreement on climate change will shape action. Conceptually, we will need a different understanding of global health and its ultimate goals - the health of people can no longer be seen separate from the health of the planet and wealth measured by parameters of growth will no longer ensure health.

  12. Global Health Governance Challenges 2016 – Are We Ready?

    Directory of Open Access Journals (Sweden)

    Ilona Kickbusch

    2016-06-01

    Full Text Available The year 2016 could turn out to be a turning point for global health, new political realities and global insecurities will test governance and financing mechanisms in relation to both people and planet. But most importantly political factors such as the global power shift and “the rise of the rest” will define the future of global health. A new mix of health inequity and security challenges has emerged and the 2015 humanitarian and health crises have shown the limits of existing systems. The global health as well as the humanitarian system will have to prove their capacity to respond and reform. The challenge ahead is deeply political, especially for the rising political actors. They are confronted with the consequences of a model of development that has neglected sustainability and equity, and was built on their exploitation. Some direction has been given by the path breaking international conferences in 2015. Especially the agreement on the Sustainable Development Goals (SDGs and the Paris agreement on climate change will shape action. Conceptually, we will need a different understanding of global health and its ultimate goals - the health of people can no longer be seen separate from the health of the planet and wealth measured by parameters of growth will no longer ensure health.

  13. Leveraging Emerging Technologies to Address Specific Learning Challenges and Derive Authentic Learning in Mathematics for Business at Africa University - Zimbabwe

    OpenAIRE

    Agrippah Kandiero; Nelson Jagero

    2014-01-01

    Emerging Technologies have been put forward by many theorists and researchers in the field of education as the key to 21st century pedagogy alternative, with promise to address learning challenges and provide a platform for authentic learning. This paper reports on use of Emerging Technologies to address learning challenges and derive authentic learning in a Mathematics for Business undergraduate course at Africa University. The research was motivated by an authentic learning challenge based ...

  14. Nation state and the challenge of globalization: Project draft

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    Obrenović Zoran G.

    2002-01-01

    Full Text Available This project draft discusses the issues facing a nation state in the dynamic processes of globalization. First, the term globalization is tentatively defined as a decentralized process of condensation and homogenization of space and time. Then, the ambivalent structure of the globalization discourse, i.e. its semantic and pragmatic dimensions, are shown. The neo-liberal viewpoint is explored of the erosion and weakening of the nation state within the global capitalist power, both in terms of its (state's traditional functions, and in terms of its internal and external sovereignty. Against the neo-liberal thesis about the decline of the nation state many empirical arguments have been offered. Some of these are presented in this text. The main point of this argumentation consists in a general view that the decline of the nation state is strongly linked with the process of globalization. In view of the critical argumentation included in the paper, it is argued that in the environment of global processes only the societies which have a strong state behind them have a chance to succeed. Politics, not economy, still dominates international relations. Emphasis on state politics opens a new perspective in discussing the process of globalization. Current globalization processes cannot be judged accurately unless geopolitical interests and the changing balance of world power are understood. Finally, the paper points to the ideological nature of the neo-liberal discourse of globalization, questioning another basic assumption of the latter, namely, the idea that the process of globalization is at the same time a process of emancipation. By challenging the positing of a necessary link between globalization and emancipation we formulate a position that allows for a normative critique of current processes.

  15. Performance Characterization of Global Address Space Applications: A Case Study with NWChem

    Energy Technology Data Exchange (ETDEWEB)

    Hammond, Jeffrey R.; Krishnamoorthy, Sriram; Shende, Sameer; Romero, Nichols A.; Malony, Allen D.

    2012-02-01

    The use of global address space languages and one-sided communication for complex applications is gaining attention in the parallel computing community. However, lack of good evaluative methods to observe multiple levels of performance makes it difficult to isolate the cause of performance deficiencies and to understand the fundamental limitations of system and application design for future improvement. NWChem is a popular computational chemistry package which depends on the Global Arrays/ ARMCI suite for partitioned global address space functionality to deliver high-end molecular modeling capabilities. A workload characterization methodology was developed to support NWChem performance engineering on large-scale parallel platforms. The research involved both the integration of performance instrumentation and measurement in the NWChem software, as well as the analysis of one-sided communication performance in the context of NWChem workloads. Scaling studies were conducted for NWChem on Blue Gene/P and on two large-scale clusters using different generation Infiniband interconnects and x86 processors. The performance analysis and results show how subtle changes in the runtime parameters related to the communication subsystem could have significant impact on performance behavior. The tool has successfully identified several algorithmic bottlenecks which are already being tackled by computational chemists to improve NWChem performance.

  16. Addressing challenges to MMPI-2-RF-based testimony: questions and answers.

    Science.gov (United States)

    Ben-Porath, Yossef S

    2012-11-01

    Introduction of a new version of a psychological test brings with it challenges that can be accentuated by the adversarial nature of the legal process. In the case of the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF), these challenges can be addressed by becoming familiar with the rationale for and the methods used in revising the inventory, the information contained in the test manuals, and the growing peer-reviewed literature on the test. Potential challenges to MMPI-2-RF-based testimony are identified in this article and discussed in question and answer format. The questions guiding this discussion are based on the Daubert factors, established in 1993 by the US Supreme Court as criteria for gauging the scientific validity of proffered expert testimony. The answers to these questions apply more broadly to testimony in depositions, pre-trial hearings, and at trial. Consideration of the MMPI-2-RF in light of the Daubert factors indicates that the instrument has been subjected to extensive empirical testing and that a substantial peer-reviewed literature is available to guide and support its use. Information about the known and potential rate of error associated with MMPI-2-RF scores is available, and standard procedures for administration, scoring, and interpretation of the inventory are detailed in the test administration manual. Indicators of MMPI-2-RF acceptance can be cited, and criticisms of the MMPI-2-RF can be addressed with information available in the test documents and an extensive, modern, and actively growing peer-reviewed literature.

  17. STaRRS in Yellowstone: Addressing Challenges Facing Student-Teacher-Scientist Partnerships

    Science.gov (United States)

    Houseal, A.; Gallagher, R.; Fuhrmann, B.; Sanford, R.

    2010-12-01

    The literature outlines many challenges faced by Student-Teacher-Scientist Partnerships (STSPs) including cultural differences between the scientific research and education communities. For example, shared vocabulary terms with dissimilar definitions can create communication problems. Other issues include accuracy in data collection, meeting the needs of a very diverse group of partners, connecting students with research science in a meaningful way, and maintaining the infrastructure necessary to develop and maintain these partnerships. Additionally, evidence, other than anecdotal, of the success of these partnerships is limited, especially as school year and research cycles are often on different schedules or have very different goals. Students, Teachers, and Rangers & Research Scientists: Investigating Systems at Mammoth Hot Springs in Yellowstone National Park (STaRRS) was an STSP developed to address some of these challenges, model some solutions within an STSP, and identify some possible outcomes for participating teachers and their students. Three strategies used to address some of these challenges that will be discussed briefly in this presentation include: (a) embedding the STSP in an already existing National Park Service environmental education program; (b) development of three types of research activities connecting teachers, students, and scientists to the research, and (c) a professional development (PD) model that included all partners in an on-going year-long process. Results from an accompanying research study will also be presented. Using a pretest-intervention-posttest design, this study revealed significant changes in attitude regarding science and scientists of participating STaRRS teachers. Student data gathered using a quasi-experimental pretest-intervention-posttest treatment and comparison group design also demonstrated significant changes in their attitudes and gains in earth science content knowledge.

  18. Addressing practical challenges in utility optimization of mobile wireless sensor networks

    Science.gov (United States)

    Eswaran, Sharanya; Misra, Archan; La Porta, Thomas; Leung, Kin

    2008-04-01

    This paper examines the practical challenges in the application of the distributed network utility maximization (NUM) framework to the problem of resource allocation and sensor device adaptation in a mission-centric wireless sensor network (WSN) environment. By providing rich (multi-modal), real-time information about a variety of (often inaccessible or hostile) operating environments, sensors such as video, acoustic and short-aperture radar enhance the situational awareness of many battlefield missions. Prior work on the applicability of the NUM framework to mission-centric WSNs has focused on tackling the challenges introduced by i) the definition of an individual mission's utility as a collective function of multiple sensor flows and ii) the dissemination of an individual sensor's data via a multicast tree to multiple consuming missions. However, the practical application and performance of this framework is influenced by several parameters internal to the framework and also by implementation-specific decisions. This is made further complex due to mobile nodes. In this paper, we use discrete-event simulations to study the effects of these parameters on the performance of the protocol in terms of speed of convergence, packet loss, and signaling overhead thereby addressing the challenges posed by wireless interference and node mobility in ad-hoc battlefield scenarios. This study provides better understanding of the issues involved in the practical adaptation of the NUM framework. It also helps identify potential avenues of improvement within the framework and protocol.

  19. GLOBALIZATION AND SMALL BUSINESSES AND ECONOMIES – CHALLENGES AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    NINKO KOSTOVSKI

    2016-08-01

    Full Text Available In this paper, we analyze the effect of globalization in general and from the viewpoint of the small and medium sized companies in the Republic of Macedonia, as a typical developing economy. Our survey of 100 managers and business owners from small and medium sized enterprises indicates that they tend to perceive the globalization with more conservative glasses as negative, or at the best, as a neutral phenomenon to their overall business prospects. However, to harvest the apparent opportunities of the globalization and to achieve the desired internationalization of their businesses, they call for intensive regional cooperation seeing it as a gateway to much harsher realms of the globalized market. The literature review and the examples from some other countries support these conservative standing of our managers and offer practical explanations why the approach towards the globalization is conservative and often even negative. Small business is important provider of new jobs, ideas and business concepts. However, with the opening of the global market it is a constant pursue for customers all around the world, having to meet their diverse and rapidly changing needs and facing extremely shortened delivery terms and product lifecycles. Many small companies, particularly from the developing countries are not adequately prepared to face the reality of this challenge. On the other hand, the big multinational companies receive more than hefty incentives to invest into the developing countries and that creates additional negative sentiments towards the globalization among the local companies.

  20. Economic optimization of a global strategy to address the pandemic threat.

    Science.gov (United States)

    Pike, Jamison; Bogich, Tiffany; Elwood, Sarah; Finnoff, David C; Daszak, Peter

    2014-12-30

    Emerging pandemics threaten global health and economies and are increasing in frequency. Globally coordinated strategies to combat pandemics, similar to current strategies that address climate change, are largely adaptive, in that they attempt to reduce the impact of a pathogen after it has emerged. However, like climate change, mitigation strategies have been developed that include programs to reduce the underlying drivers of pandemics, particularly animal-to-human disease transmission. Here, we use real options economic modeling of current globally coordinated adaptation strategies for pandemic prevention. We show that they would be optimally implemented within 27 y to reduce the annual rise of emerging infectious disease events by 50% at an estimated one-time cost of approximately $343.7 billion. We then analyze World Bank data on multilateral "One Health" pandemic mitigation programs. We find that, because most pandemics have animal origins, mitigation is a more cost-effective policy than business-as-usual adaptation programs, saving between $344.0.7 billion and $360.3 billion over the next 100 y if implemented today. We conclude that globally coordinated pandemic prevention policies need to be enacted urgently to be optimally effective and that strategies to mitigate pandemics by reducing the impact of their underlying drivers are likely to be more effective than business as usual.

  1. The credibility challenge for global fluvial flood risk analysis

    Science.gov (United States)

    Trigg, M. A.; Birch, C. E.; Neal, J. C.; Bates, P. D.; Smith, A.; Sampson, C. C.; Yamazaki, D.; Hirabayashi, Y.; Pappenberger, F.; Dutra, E.; Ward, P. J.; Winsemius, H. C.; Salamon, P.; Dottori, F.; Rudari, R.; Kappes, M. S.; Simpson, A. L.; Hadzilacos, G.; Fewtrell, T. J.

    2016-09-01

    Quantifying flood hazard is an essential component of resilience planning, emergency response, and mitigation, including insurance. Traditionally undertaken at catchment and national scales, recently, efforts have intensified to estimate flood risk globally to better allow consistent and equitable decision making. Global flood hazard models are now a practical reality, thanks to improvements in numerical algorithms, global datasets, computing power, and coupled modelling frameworks. Outputs of these models are vital for consistent quantification of global flood risk and in projecting the impacts of climate change. However, the urgency of these tasks means that outputs are being used as soon as they are made available and before such methods have been adequately tested. To address this, we compare multi-probability flood hazard maps for Africa from six global models and show wide variation in their flood hazard, economic loss and exposed population estimates, which has serious implications for model credibility. While there is around 30%-40% agreement in flood extent, our results show that even at continental scales, there are significant differences in hazard magnitude and spatial pattern between models, notably in deltas, arid/semi-arid zones and wetlands. This study is an important step towards a better understanding of modelling global flood hazard, which is urgently required for both current risk and climate change projections.

  2. Addressing the Challenges of Hepatitis C Virus Resistance and Treatment Failure

    Directory of Open Access Journals (Sweden)

    Che C. Colpitts

    2016-08-01

    Full Text Available Chronic hepatitis C is a major cause of chronic liver disease, including liver cirrhosis and hepatocellular carcinoma. The development of direct-acting antivirals (DAAs revolutionized hepatitis C virus (HCV treatment by offering genuine prospects for the first comprehensive cure of a chronic viral infection in humans. While antiviral resistance is a significant limitation for interferon-based therapies, resistance and treatment failure still appear to be present in a small fraction of patients even in state-of-the-art DAA combination therapies. Therefore, treatment failure and resistance still remain a clinical challenge for the management of patients not responding to DAAs. In this special issue of Viruses on HCV drug resistance, mechanisms of antiviral resistance for different classes of antiviral drugs are described. Furthermore, the detection and monitoring of resistance in clinical practice, the clinical impact of resistance in different patient groups and strategies to prevent and address resistance and treatment failure using complementary antiviral strategies are reviewed.

  3. Energy Sustainability: A Key Toto Addressing Environmental, Economic and Societal Challenges

    Directory of Open Access Journals (Sweden)

    Marc A. Rosen

    2013-04-01

    Full Text Available Sustainability is a critically important goal for human activity and development, particularly in the area of energy. Energy resources are critical for economic development and living standards, but their use causes significant environmental impacts. Given the pervasiveness of energy use, energy sustainability is a key to addressing environmental, economic and societal challenges. To achieve energy sustainability, many factors that need to be including harnessing sustainable energy sources, utilizing sustainable energy carriers, increasing efficiency, reducing environmental impact and improving socioeconomic acceptability (e.g., community involvement, affordability, equity and land use. To demonstrate the factors and their importance to energy sustainability, the Red-Mediterranean-Dead Seas Canal Project is considered as a case study. Conclusions are provided related both to steps for energy sustainability.

  4. ASTERICS : Addressing Cross-Cutting Synergies and Common Challenges for the Next Decade Astronomy Facilities

    CERN Document Server

    Pasian, Fabio; Genova, Francoise; Lamanna, Giovanni; Serjeant, Stephen; Szomoru, Arpad; van der Meer, Rob

    2016-01-01

    The large infrastructure projects for the next decade will allow a new quantum leap in terms of new possible science. ESFRI, the European Strategy Forum on Research Infrastructures, a strategic initiative to develop the scientific integration of Europe, has identified four facilities (SKA, CTA, KM3Net and E-ELT) deserving priority in support. The ASTERICS project aims to address the cross-cutting synergies and common challenges shared by the various Astronomy ESFRI and other world-class facilities. The project (22 partners across Europe) is funded by the EU Horizon 2020 programme with 15 MEuro in 4 years. It brings together for the first time the astronomy, astrophysics and particle astrophysics communities, in addition to other related research infrastructures.

  5. Addressing the Challenges of Hepatitis C Virus Resistance and Treatment Failure.

    Science.gov (United States)

    Colpitts, Che C; Baumert, Thomas F

    2016-08-16

    Chronic hepatitis C is a major cause of chronic liver disease, including liver cirrhosis and hepatocellular carcinoma. The development of direct-acting antivirals (DAAs) revolutionized hepatitis C virus (HCV) treatment by offering genuine prospects for the first comprehensive cure of a chronic viral infection in humans. While antiviral resistance is a significant limitation for interferon-based therapies, resistance and treatment failure still appear to be present in a small fraction of patients even in state-of-the-art DAA combination therapies. Therefore, treatment failure and resistance still remain a clinical challenge for the management of patients not responding to DAAs. In this special issue of Viruses on HCV drug resistance, mechanisms of antiviral resistance for different classes of antiviral drugs are described. Furthermore, the detection and monitoring of resistance in clinical practice, the clinical impact of resistance in different patient groups and strategies to prevent and address resistance and treatment failure using complementary antiviral strategies are reviewed.

  6. Medical mycology and fungal immunology: new research perspectives addressing a major world health challenge.

    Science.gov (United States)

    Gow, Neil A R; Netea, Mihai G

    2016-12-05

    Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV. These statistics evidence fungal infections as a major threat to human health and a major burden to healthcare budgets worldwide. Those patients who are at greatest risk of life-threatening fungal infections include those who have weakened immunity or have suffered trauma or other predisposing infections such as HIV. To address these global threats to human health, more research is urgently needed to understand the immunopathology of fungal disease and human disease susceptibility in order to augment the advances being made in fungal diagnostics and drug development. Here, we highlight some recent advances in basic research in medical mycology and fungal immunology that are beginning to inform clinical decisions and options for personalized medicine, vaccine development and adjunct immunotherapies.This article is part of the themed issue 'Tackling emerging fungal threats to animal health, food security and ecosystem resilience'. © 2016 The Authors.

  7. Medical mycology and fungal immunology: new research perspectives addressing a major world health challenge

    Science.gov (United States)

    Gow, Neil A. R.; Netea, Mihai G.

    2016-01-01

    Fungi cause more than a billion skin infections, more than 100 million mucosal infections, 10 million serious allergies and more than a million deaths each year. Global mortality owing to fungal infections is greater than for malaria and breast cancer and is equivalent to that owing to tuberculosis (TB) and HIV. These statistics evidence fungal infections as a major threat to human health and a major burden to healthcare budgets worldwide. Those patients who are at greatest risk of life-threatening fungal infections include those who have weakened immunity or have suffered trauma or other predisposing infections such as HIV. To address these global threats to human health, more research is urgently needed to understand the immunopathology of fungal disease and human disease susceptibility in order to augment the advances being made in fungal diagnostics and drug development. Here, we highlight some recent advances in basic research in medical mycology and fungal immunology that are beginning to inform clinical decisions and options for personalized medicine, vaccine development and adjunct immunotherapies. This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’. PMID:28080988

  8. Global women's health in 2010: facing the challenges.

    Science.gov (United States)

    Lester, Felicia; Benfield, Nerys; Fathalla, Mohamed M F

    2010-11-01

    Women's health is closely linked to a nation's level of development, with the leading causes of death in women in resource-poor nations attributable to preventable causes. Unlike many health problems in rich nations, the cure relies not only on the discovery of new medications or technology but also getting basic services to the people who need them most and addressing underlying injustice. In order to do this, political will and financial resources must be dedicated to developing and evaluating a scaleable approach to strengthen health systems, support community-based programs, and promote widespread campaigns to address gender inequality, including promoting girls' education. The Millennium Development Goals (MDGs) have highlighted the importance of addressing maternal health and promoting gender equality for the overall development strategy of a nation. We must capitalize on the momentum created by this and other international campaigns and continue to advocate for comprehensive strategies to improve global women's health.

  9. Developing sustainable global health technologies: insight from an initiative to address neonatal hypothermia.

    Science.gov (United States)

    Gupta, Rajesh; Patel, Rajan; Murty, Naganand; Panicker, Rahul; Chen, Jane

    2015-02-01

    Relative to drugs, diagnostics, and vaccines, efforts to develop other global health technologies, such as medical devices, are limited and often focus on the short-term goal of prototype development instead of the long-term goal of a sustainable business model. To develop a medical device to address neonatal hypothermia for use in resource-limited settings, we turned to principles of design theory: (1) define the problem with consideration of appropriate integration into relevant health policies, (2) identify the users of the technology and the scenarios in which the technology would be used, and (3) use a highly iterative product design and development process that incorporates the perspective of the user of the technology at the outset and addresses scalability. In contrast to our initial idea, to create a single device, the process guided us to create two separate devices, both strikingly different from current solutions. We offer insights from our initial experience that may be helpful to others engaging in global health technology development.

  10. Challenges and opportunities in mapping land use intensity globally

    DEFF Research Database (Denmark)

    Kuemmerle, Tobias; Erb, Karlheinz; Meyfroidt, Patrick;

    2013-01-01

    we lack appropriate datasets to assess land use intensity across broad geographic extents. Here, we review the state of the art regarding approaches for mapping land use intensity and provide a comprehensive overview of available global-scale datasets on land use intensity. We also outline major...... challenges and opportunities for mapping land use intensity for cropland, grazing, and forestry systems, and identify key issues for future research. © 2013 Elsevier B.V. All rights reserved....

  11. Addressing Emerging Risks: Scientific and Regulatory Challenges Associated with Environmentally Persistent Free Radicals.

    Science.gov (United States)

    Dugas, Tammy R; Lomnicki, Slawomir; Cormier, Stephania A; Dellinger, Barry; Reams, Margaret

    2016-06-08

    Airborne fine and ultrafine particulate matter (PM) are often generated through widely-used thermal processes such as the combustion of fuels or the thermal decomposition of waste. Residents near Superfund sites are exposed to PM through the inhalation of windblown dust, ingestion of soil and sediments, and inhalation of emissions from the on-site thermal treatment of contaminated soils. Epidemiological evidence supports a link between exposure to airborne PM and an increased risk of cardiovascular and pulmonary diseases. It is well-known that during combustion processes, incomplete combustion can lead to the production of organic pollutants that can adsorb to the surface of PM. Recent studies have demonstrated that their interaction with metal centers can lead to the generation of a surface stabilized metal-radical complex capable of redox cycling to produce ROS. Moreover, these free radicals can persist in the environment, hence their designation as Environmentally Persistent Free Radicals (EPFR). EPFR has been demonstrated in both ambient air PM2.5 (diameter < 2.5 µm) and in PM from a variety of combustion sources. Thus, low-temperature, thermal treatment of soils can potentially increase the concentration of EPFR in areas in and around Superfund sites. In this review, we will outline the evidence to date supporting EPFR formation and its environmental significance. Furthermore, we will address the lack of methodologies for specifically addressing its risk assessment and challenges associated with regulating this new, emerging contaminant.

  12. Addressing challenges for future strategic-level emergency management: reframing, networking, and capacity-building.

    Science.gov (United States)

    Bosomworth, Karyn; Owen, Christine; Curnin, Steven

    2017-04-01

    The mounting frequency and intensity of natural hazards, alongside growing interdependencies between social-technical and ecological systems, are placing increased pressure on emergency management. This is particularly true at the strategic level of emergency management, which involves planning for and managing non-routine, high-consequence events. Drawing on the literature, a survey, and interviews and workshops with Australia's senior emergency managers, this paper presents an analysis of five core challenges that these pressures are creating for strategic-level emergency management. It argues that emphasising 'emergency management' as a primary adaptation strategy is a retrograde step that ignores the importance of addressing socio-political drivers of vulnerabilities. Three key suggestions are presented that could assist the country's strategic-level emergency management in tackling these challenges: (i) reframe emergency management as a component of disaster risk reduction rather than them being one and the same; (ii) adopt a network governance approach; and (iii) further develop the capacities of strategic-level emergency managers. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

  13. Re-thinking wastewater landscapes: combining innovative strategies to address tomorrow's urban wastewater treatment challenges.

    Science.gov (United States)

    Smith, B R

    2009-01-01

    Most major cities worldwide face urban water management challenges relating to drinking supply, stormwater and wastewater treatment, and ecological preservation. In light of climate change and finite natural resources, addressing these challenges in sustainable ways will require innovative solutions arising from interdisciplinary collaboration. This article summarizes five major urban water management strategies that bridge the fields of engineering, ecology, landscape architecture, and urban planning. A conceptual implementation of these strategies is demonstrated through a design for a small constructed wetland treatment system in San Francisco, California. The proposed decentralized system described in this article consists of a detention basin, vegetated and open free water surface wetlands, and ultraviolet disinfection. In wet weather, the system would detain and treat combined sewer discharges (CSD), and in dry weather it would treat residential greywater for toilet flushing and irrigation in a nearby neighborhood. It is designed to adapt over time to changing climatic conditions and treatment demands. Importantly, this proposal demonstrates how constructed wetland engineers can incorporate multiple benefits into their systems, offering a vision of how wastewater infrastructure can be an attractive community, educational, recreational, and habitat amenity through the integration of engineering, ecology, and landscape design.

  14. The impact of globalization and environmental change on health: challenges for nurse education.

    Science.gov (United States)

    Kirk, Maggie

    2002-01-01

    The environment is an established domain of nursing knowledge, but some authors argue that the traditional perspective is too narrowly focused on the immediate environment to appreciate the relevance of the global environment. This article explores how human activities are bringing about global changes through their impact on biogeochemical cycles, land use and mobility of organisms, altering biodiversity and climate, and ultimately compromising the ecosystems services that sustain our planet. The consequences of global change for population health are examined, including the emergence of drug-resistant diseases, and the implications of climate warming and pollution for health. Addressing these issues presents a considerable challenge for nursing at all levels, in promoting sustainable policies, integrating environmental considerations into clinical practice, and in the nursing role as health educators. The greatest challenge is to education, to raise awareness of the relevance and importance of the global environment to health, and to empower nurses with sufficient understanding of the issues to apply them to practice, participate in debate and contribute to policy-making that aims to reduce the burden of global changes. The extent to which the profession is prepared to diversify in response to these challenges is discussed.

  15. Technological challenges of addressing new and more complex migrating products from novel food packaging materials.

    Science.gov (United States)

    Munro, Ian C; Haighton, Lois A; Lynch, Barry S; Tafazoli, Shahrzad

    2009-12-01

    The risk assessment of migration products resulting from packaging material has and continues to pose a difficult challenge. In most jurisdictions, there are regulatory requirements for the approval or notification of food contact substances that will be used in packaging. These processes generally require risk assessment to ensure safety concerns are addressed. The science of assessing food contact materials was instrumental in the development of the concept of Threshold of Regulation and the Threshold of Toxicological Concern procedures. While the risk assessment process is in place, the technology of food packaging continues to evolve to include new initiatives, such as the inclusion of antimicrobial substances or enzyme systems to prevent spoilage, use of plastic packaging intended to remain on foods as they are being cooked, to the introduction of more rigid, stable and reusable materials, and active packaging to extend the shelf-life of food. Each new technology brings with it the potential for exposure to new and possibly novel substances as a result of migration, interaction with other chemical packaging components, or, in the case of plastics now used in direct cooking of products, degradation products formed during heating. Furthermore, the presence of trace levels of certain chemicals from packaging that were once accepted as being of low risk based on traditional toxicology studies are being challenged on the basis of reports of adverse effects, particularly with respect to endocrine disruption, alleged to occur at very low doses. A recent example is the case of bisphenol A. The way forward to assess new packaging technologies and reports of very low dose effects in non-standard studies of food contact substances is likely to remain controversial. However, the risk assessment paradigm is sufficiently robust and flexible to be adapted to meet these challenges. The use of the Threshold of Regulation and the Threshold of Toxicological Concern concepts may

  16. Ethics in occupational health: deliberations of an international workgroup addressing challenges in an African context.

    Science.gov (United States)

    London, Leslie; Tangwa, Godfrey; Matchaba-Hove, Reginald; Mkhize, Nhlanhla; Nwabueze, Remi; Nyika, Aceme; Westerholm, Peter

    2014-06-23

    International codes of ethics play an important role in guiding professional practice in developing countries. In the occupational health setting, codes developed by international agencies have substantial import on protecting working populations from harm. This is particularly so under globalisation which has transformed processes of production in fundamental ways across the globe. As part of the process of revising the Ethical Code of the International Commission on Occupational Health, an Africa Working Group addressed key challenges for the relevance and cogency of an ethical code in occupational health for an African context through an iterative consultative process. Firstly, even in the absence of strong legal systems of enforcement, and notwithstanding the value of legal institutionalisation of ethical codes, guidelines alone may offer advantageous routes to enhancing ethical practice in occupational health. Secondly, globalisation has particularly impacted on health and safety at workplaces in Africa, challenging occupational health professionals to be sensitive to, and actively redress imbalance of power. Thirdly, the different ways in which vulnerability is exemplified in the workplace in Africa often places the occupational health professional in invidious positions of Dual Loyalty. Fourth, the particular cultural emphasis in traditional African societies on collective responsibilities within the community impacts directly on how consent should be sought in occupational health practice, and how stigma should be dealt with, balancing individual autonomy with ideas of personhood that are more collective as in the African philosophy of ubuntu. To address stigma, practitioners need to be additionally sensitive to how power imbalances at the workplace intersect with traditional cultural norms related to solidarity. Lastly, particularly in the African context, the inseparability of workplace and community means that efforts to address workplace hazards demand

  17. Ethics in occupational health: deliberations of an international workgroup addressing challenges in an African context

    Science.gov (United States)

    2014-01-01

    Background International codes of ethics play an important role in guiding professional practice in developing countries. In the occupational health setting, codes developed by international agencies have substantial import on protecting working populations from harm. This is particularly so under globalisation which has transformed processes of production in fundamental ways across the globe. As part of the process of revising the Ethical Code of the International Commission on Occupational Health, an Africa Working Group addressed key challenges for the relevance and cogency of an ethical code in occupational health for an African context through an iterative consultative process. Discussion Firstly, even in the absence of strong legal systems of enforcement, and notwithstanding the value of legal institutionalisation of ethical codes, guidelines alone may offer advantageous routes to enhancing ethical practice in occupational health. Secondly, globalisation has particularly impacted on health and safety at workplaces in Africa, challenging occupational health professionals to be sensitive to, and actively redress imbalance of power. Thirdly, the different ways in which vulnerability is exemplified in the workplace in Africa often places the occupational health professional in invidious positions of Dual Loyalty. Fourth, the particular cultural emphasis in traditional African societies on collective responsibilities within the community impacts directly on how consent should be sought in occupational health practice, and how stigma should be dealt with, balancing individual autonomy with ideas of personhood that are more collective as in the African philosophy of ubuntu. To address stigma, practitioners need to be additionally sensitive to how power imbalances at the workplace intersect with traditional cultural norms related to solidarity. Lastly, particularly in the African context, the inseparability of workplace and community means that efforts to address

  18. Globalization of international migration: Social challenges and policy implication

    Directory of Open Access Journals (Sweden)

    I A Aleshkovski

    2017-12-01

    Full Text Available In the second half of the XX century, the humankind witnessed the insurmountable and irreversible power of globalization processes, which influence all spheres of social life and establish a global system of interdependency between countries and nations. Globalization within impetuous changes in global political, social and economic systems has determined dramatic shifts in the international migration processes that lead to the new stage of migration history. In nowadays globalized world, international migration has become a reality for almost all corners of the globe. The author considers features of the recent trends of international migration: the unprecedented growth of the international migration flows; the widening geography of international migration that involves nearly all countries of the world; qualitative changes in the structure of international migration flows; the key role of economic migration; the permanent growth and structural intricateness of irregular migration; the increasing scale and geographical widening of forced migration; the growing importance of international migration for the demographic development of the world, countries of both origin and destination. All these trends combined prove that the international migration patterns have become more complex. The author analyzes the legal framework of the international migration processes, and gives recommendations on the ways to improve the control and regulation of migration processes. Specific issues related to the social challenges of international migration are also discussed in the article.

  19. Addressing the challenges of GRACE application in basins with hydraulic fracturing activity

    Science.gov (United States)

    Read, L.; Ruybal, C.; Hogue, T. S.; Hinojosa, M. P.

    2016-12-01

    Despite the growing number of studies that employ GRACE to quantify groundwater resources we have found no published studies on whether GRACE is also accounting for subsurface mass redistributions related to energy development activities from oil production, water production, and wastewater injection. Given the similar densities of water and crude oil (water is 1.0g/cc, crude oil is 0.8-0.9g/cc) and the fact that large volumes of oil and water are extracted on a monthly basis for hydraulic fracturing or reinjected as a means of waste disposal, it is important to determine whether GRACE is detecting mass redistributions from energy development to be able to correctly infer changes in water mass. The purpose of this study is to investigate whether GRACE measurements are impacted by energy development activities and offer a methodology for determining whether this activity should be considered when evaluating changes in terrestrial water storage, groundwater storage, or any other prediction involving quantification of groundwater. To address this question we compiled a dataset from the Bakken Play in North Dakota to use as a case study, where oil production was significant and increased exponentially from 2002-2015, and groundwater withdrawals for agriculture were relatively stable and limited. Preliminary results indicate that oil and gas production is of a similar scale and thus important to include when calculating groundwater changes. Broadly, this research addresses the challenges and uncertainties in applying GRACE to quantify groundwater or terrestrial water changes in energy-active basins, namely in accounting for oil reservoir changes, production, and injection rates, as well as the process of data collection in proprietary systems.

  20. CAWR: Two institutions join forces in a cluster by addressing the grand challenges of water research

    Science.gov (United States)

    Jaeckel, Greta; Braeckevelt, Mareike

    2017-04-01

    The Center for Advanced Water Research (CAWR) brings together the water competences of two German research institutions: Helmholtz Centre for Environmental Research - UFZ and the Technische Universität Dresden (TUD). Highly qualified scientists are jointly tackling some of the key challenges in the water sector in an outstanding breadth of research topics and at the same time with a profound disciplinary expertise. Our mission is: "Save water for humans and environment", because water in a good quality and adequate quantity is a fundamental basis of life for humankind and the environment. In many global challenges, such as food or energy security, human health and ecosystems, flood defence and droughts or the provision of drinking water and sanitation systems, water is becoming a very critical element for a sustainable society in Germany, in Europe and worldwide. The CAWR focusses its work on the fields of research, education & training as well as transfer. The CAWR was established in 2013. Over 3 years the activities within the three pillars and the six thematic priority research fields ( 1) Understanding processes: water cycle and water quality, 2): Water quantity and scarcity in the regional context, 3): Urban Water Systems, 4): Methods of data collection and information processing, 5): Societal and climate change, 6): Water governance) were presented within: • the scientific community (newsletters, publication highlights, workshops with different new formats, conferences) • to national and international stakeholders from policy, industry and society (workshops, opinion papers) • public media (TV, radio stations, Newspapers, brochures, videoclips via youtube…) This PICO presentation by Greta Jäckel (scientific management of CAWR) should show which tools for the presentation of research results are useful and which influence they have on different target groups. A bunch of examples for effective and also less successful instruments to present important

  1. Planetary Atmosphere and Surfaces Chamber (PASC: A Platform to Address Various Challenges in Astrobiology

    Directory of Open Access Journals (Sweden)

    Eva Mateo-Marti

    2014-08-01

    . Furthermore, the stability and presence of certain minerals on planetary surfaces and the potential habitability of microorganisms under various planetary environmental conditions can be studied using our apparatus. Therefore, these simulation chambers can address multiple different challenging and multidisciplinary astrobiological studies.

  2. Planetary Atmosphere and Surfaces Chamber (PASC): A Platform to Address Various Challenges in Astrobiology

    Science.gov (United States)

    Mateo-Marti, Eva

    2014-08-01

    stability and presence of certain minerals on planetary surfaces and the potential habitability of microorganisms under various planetary environmental conditions can be studied using our apparatus. Therefore, these simulation chambers can address multiple different challenging and multidisciplinary astrobiological studies.

  3. Addressing the Challenges in Tonsillectomy Research to Inform Health Care Policy: A Review.

    Science.gov (United States)

    Mandavia, Rishi; Schilder, Anne G M; Dimitriadis, Panagiotis A; Mossialos, Elias

    2017-09-01

    Eighty-five percent of investment in medical research has been wasted, with lack of effect on clinical practice and policy. There is increasing effort to improve the likelihood of research being used to influence clinical practice and policy. Tonsillectomy is one of the most common otorhinolaryngologic surgical procedures, and its frequency, cost, and morbidity create a clear need for evidence-based guidelines and policy. The first systematic review on tonsillectomy was conducted 40 years ago and highlighted the lack of definitive evidence for the procedure. Since that study, the body of evidence has still not been able to sufficiently inform policy. This review provides an overview of the key challenges in research to inform tonsillectomy policy and recommendations to help bridge the evidence-policy gap. The challenges in using research to inform policy can be summarized as 4 main themes: (1) non-policy-focused evidence and lack of available evidence, (2) quality of evidence, (3) communication of research findings, and (4) coordinating time frames. Researchers and decision makers should be aware of the limitations of research designs and conflicts of interest that can undermine policy decisions. Researchers must work with decision makers and patients throughout the research process to identify areas of unmet need and political priority, align research and policy time frames, and disseminate research findings. Incentives for researchers should be reorganized to promote dissemination of findings. It is important to consider why evidence gaps in tonsillectomy research have not been addressed during the past 40 years despite considerable investment in time and resources. These findings and recommendations will help produce research that is more responsive to policy gaps and more likely to result in policy changes.

  4. China confidential: methodological and ethical challenges in global nursing historiography.

    Science.gov (United States)

    Grypma, Sonya; Wu, Na

    2012-01-01

    As the history of nursing as a field of scholarship expands its global consciousness, it seems timely to join other scholars of international history in rethinking conventional approaches to historiography. The lament by mission scholars at the invisibility of nurses and indigenous workers in historical mission records coincides with calls by China scholars to reconsider traditional reliance on English-language data generation and interpretation for an English-speaking audience. In a similar way, nursing scholars are challenging historians of nursing to find ways to build a body of scholarship and a cadre of scholars that can open up new linguistic and cultural space for vibrant discussion and dialogue. Drawing on Sonya Grypma's research on the role of missionary nurses in the development of modern nursing in China and based on a series of interviews by the authors in China of participants with ties to a former Canadian mission hospital, we explore methodological and ethical challenges in global nursing historiography. By offering insights gleaned from our early attempts to capture voices not included in conventional mission records, we hope to stimulate more dialogue about conceptual and structural issues central to a "new" global nursing historiography.

  5. Securing classification and regulatory approval for deepwater projects: management challenges in a global environment

    Energy Technology Data Exchange (ETDEWEB)

    Feijo, Luiz P.; Burton, Gareth C. [American Bureau of Shipping (ABS), Rio de Janeiro, RJ (Brazil)

    2008-07-01

    As the offshore industry continues to develop and move into increasingly deeper waters, technological boundaries are being pushed to new limits. Along with these advances, the design, fabrication and installation of deepwater oil and gas projects has become an increasingly global endeavor. After providing an overview of the history and role of Classification Societies, this paper reviews the challenges of securing classification and regulatory approval in a global environment. Operational, procedural and technological changes which one Classification Society; the American Bureau of Shipping, known as ABS, has implemented to address these challenges are presented. The result of the changes has been a more customized service aiming at faster and more streamlined classification approval process. (author)

  6. Engaging undergraduates to solve global health challenges: a new approach based on bioengineering design.

    Science.gov (United States)

    Oden, Maria; Mirabal, Yvette; Epstein, Marc; Richards-Kortum, Rebecca

    2010-09-01

    Recent reports have highlighted the need for educational programs to prepare students for careers developing and disseminating new interventions that improve global public health. Because of its multi-disciplinary, design-centered nature, the field of Biomedical Engineering can play an important role in meeting this challenge. This article describes a new program at Rice University to give undergraduate students from all disciplines a broad background in bioengineering and global health and provides an initial assessment of program impact. Working in partnership with health care providers in developing countries, students in the Beyond Traditional Borders (BTB) initiative learn about health challenges of the poor and put this knowledge to work immediately, using the engineering design process as a framework to formulate solutions to complex global health challenges. Beginning with a freshman design project and continuing through a capstone senior design course, the BTB curriculum uses challenges provided by partners in the developing world to teach students to integrate perspectives from multiple disciplines, and to develop leadership, communication, and teamwork skills. Exceptional students implement their designs under the guidance of clinicians through summer international internships. Since 2006, 333 students have designed more than 40 technologies and educational programs; 28 have been implemented in sub-Saharan Africa, Latin America, the Caribbean, southeast Asia, and the United States. More than 18,000 people have benefited from these designs. 95% of alumni who completed an international internship reported that participation in the program changed or strengthened their career plans to include a focus on global health medicine, research, and/or policy. Empowering students to use bioengineering design to address real problems is an effective way to teach the new generation of leaders needed to solve global health challenges.

  7. Global precipitation measurement (GPM) mission core spacecraft systems engineering challenges

    Science.gov (United States)

    Bundas, David J.; O'Neill, Deborah; Rhee, Michael; Feild, Thomas; Meadows, Gary; Patterson, Peter

    2006-09-01

    The Global Precipitation Measurement (GPM) Mission is a collaboration between the National Aeronautics and Space Administration (NASA) and the Japanese Aerospace Exploration Agency (JAXA), and other US and international partners, with the goal of monitoring the diurnal and seasonal variations in precipitation over the surface of the earth. These measurements will be used to improve current climate models and weather forecasting, and enable improved storm and flood warnings. This paper gives an overview of the mission architecture and addresses the status of some key trade studies, including the geolocation budgeting, design considerations for spacecraft charging, and design issues related to the mitigation of orbital debris.

  8. Addressing Challenges to the Design & Test of Operational Lighting Environments for the International Space Station

    Science.gov (United States)

    Clark, Toni A.

    2014-01-01

    In our day to day lives, the availability of light, with which to see our environment, is often taken for granted. The designers of land based lighting systems use sunlight and artificial light as their toolset. The availability of power, quantity of light sources, and variety of design options are often unlimited. The accessibility of most land based lighting systems makes it easy for the architect and engineer to verify and validate their design ideas. Failures with an implementation, while sometimes costly, can easily be addressed by renovation. Consider now, an architectural facility orbiting in space, 260 miles above the surface of the earth. This human rated architectural facility, the International Space Station (ISS) must maintain operations every day, including life support and appropriate human comforts without fail. The facility must also handle logistics of regular shipments of cargo, including new passengers. The ISS requires accommodations necessary for human control of machine systems. Additionally, the ISS is a research facility and supports investigations performed inside and outside its livable volume. Finally, the facility must support remote operations and observations by ground controllers. All of these architectural needs require a functional, safe, and even an aesthetic lighting environment. At Johnson Space Center, our Habitability and Human Factors team assists our diverse customers with their lighting environment challenges, via physical test and computer based analysis. Because of the complexity of ISS operational environment, our team has learned and developed processes that help ISS operate safely. Because of the dynamic exterior lighting environment, uses computational modeling to predict the lighting environment. The ISS' orbit exposes it to a sunrise every 90 minutes, causing work surfaces to quickly change from direct sunlight to earthshine to total darkness. Proper planning of vehicle approaches, robotics operations, and crewed

  9. Climate change and forest diseases: using todays knowledge to address future challenges

    Energy Technology Data Exchange (ETDEWEB)

    Sturrock, R. N.

    2012-11-01

    The health of the earths forests and urban green spaces is increasingly challenged by the outcomes of human activities, including global climate change. As climate changes, the role and impact of diseases on trees in both forest ecosystems and in urban settings will also change. Knowledge of relationships between climate variables and diseases affecting forest and urban trees is reviewed, with specific emphasis on those affecting foliage, shoots, and stems. Evidence that forest diseases are already responding to the earths changing climate is examined (e.g., Dothistroma needle blight in northern British Columbia) as are predicted scenarios for future changes in impact on forests by other tree diseases. Outbreaks of tree diseases caused by native and alien pathogens are predicted to become more frequent and intense this and other general predictions about the effects of climate change on forest and tree diseases are discussed. Despite the uncertainty that accompanies such predictions it is imperative that researchers, forest and urban tree managers, and policy makers work together to develop and implement management strategies that enhance the resilience of the worlds forests and urbanized trees. Strategies discussed include monitoring, forecasting, planning, and mitigation. (Author) 60 refs.

  10. Upscaling the Use of Fallout Radionuclides in Soil Erosion and Sediment Budget Investigations: Addressing the Challenge

    Directory of Open Access Journals (Sweden)

    D.E. Walling

    2014-09-01

    Full Text Available The application of fallout radionuclides in soil erosion investigations and related sediment budget studies has provided a widely used tool for improving understanding of soil erosion and sediment transfer processes. However, most studies using fallout radionuclides undertaken to date have focussed on small areas. This focus on small areas reflects both the issues addressed and practical constraints associated with sample collection and analysis. Increasing acceptance of the important role of fine sediment in degrading aquatic habitats and in the transfer and fate of nutrients and contaminants within terrestrial and fluvial systems has emphasised the need to consider larger areas and the catchment or regional scale. The need to upscale existing approaches to the use of fallout radionuclides to larger areas represents an important challenge. This contribution provides a brief review of existing and potential approaches to upscaling the use of fallout radionuclides and presents two examples where such approaches have been successfully applied. These involve a national scale assessment of soil erosion rates in England and Wales based on 137Cs measurements and an investigation of the sediment budgets of three small/intermediate-size catchments in southern Italy.

  11. Assessing the impact of defining a global priority research agenda to address HIV-associated tuberculosis.

    Science.gov (United States)

    Odone, Anna; Matteelli, Alberto; Chiesa, Valentina; Cella, Paola; Ferrari, Antonio; Pezzetti, Federica; Signorelli, Carlo; Getahun, Haileyesus

    2016-11-01

    In 2010, the WHO issued 77 priority research questions (PRQs) to address HIV-associated TB. Objective of the this study was to assess the impact of defining the research agenda in stimulating and directing research around priority research questions. We used number and type of scientific publications as a proxy to quantitatively assess the impact of research agenda setting. We conducted 77 single systematic reviews - one for every PRQ - building 77 different search strategies using PRQs' keywords. Multivariate logistic regression models were applied to assess the quantity and quality of research produced over time and accounting for selected covariates. In 2009-2015, PRQs were addressed by 1631 publications (median: 11 studies published per PRQ, range 1-96). The most published area was 'Intensified TB case finding' (median: 23 studies/PRQ, range: 2-74). The majority (62.1%, n = 1013) were published as original studies, and more than half (58%, n = 585) were conducted in the African region. Original studies' publication increased over the study period (P trend = <0.001). They focused more on the 'Intensified TB case finding' (OR = 2.17, 95% CI: 1.56-2.93) and 'Drug-resistant TB and HIV infection' (OR = 2.12, 95% CI: 1.47-3.06) areas than non-original studies. Original studies were published in journals of lower impact factor and received a smaller number of citations than non-original studies (OR = 0.54, 95% CI: 0.42-0.69). The generation of evidence to address PRQs has increased over time particularly in selected fields. Setting a priority research agenda for HIV-associated TB might have positively influenced the direction and the conduct of research and contributed to the global response to such a major threat to health. © 2016 John Wiley & Sons Ltd.

  12. Global progress against cancer-challenges and oppor tunities

    Institute of Scientific and Technical Information of China (English)

    Frédéric Biemar; Margaret Foti

    2013-01-01

    The last ten years have seen remarkable progress in cancer research. However, despite significant breakthroughs in the understanding, prevention, and treatment of cancer, the disease continues to affect millions of people worldwide. Cancer’s complexity compounded with ifnancial, policy and regulatory roadblocks has slowed the rate of progress being made against cancer. In this paper, we review a few of the most recent breakthroughs that are fueling medical advances and bringing new hope for patients affected by this devastating disease. We also address the challenges facing us and the opportunities to accelerate future progress against cancer. The efforts of the American Association for Cancer Research (AACR) to address the cancer burden already extend beyond the borders of the United States of America. hTe AACR is committed to increasing its efforts to stem the tide of cancer worldwide by promoting innovative programs, strategies, and initiatives for cancer researchers and all those engaged in cancer-related biomedical sciences around the world.

  13. Operationalizing the One Health approach: the global governance challenges.

    Science.gov (United States)

    Lee, Kelley; Brumme, Zabrina L

    2013-10-01

    While there has been wide-ranging commitment to the One Health approach, its operationalisation has so far proven challenging. One Health calls upon the human, animal and environmental health sectors to cross professional, disciplinary and institutional boundaries, and to work in a more integrated fashion. At the global level, this paper argues that this vision is hindered by dysfunctions characterising current forms of global health governance (GHG), namely institutional proliferation, fragmentation, competition for scarce resources, lack of an overarching authority, and donor-driven vertical programmes. This has contributed, in part, to shortcomings in how One Health has been articulated to date. An agreed operational definition of One Health among key global institutions, efforts to build One Health institutions from the ground up, comparative case studies of what works or does not work institutionally, and high-level global support for research, training and career opportunities would all help to enable One Health to help remedy, and not be subsumed by, existing dysfunctions in GHG.

  14. The status and challenge of global fire modelling

    Science.gov (United States)

    Hantson, Stijn; Arneth, Almut; Harrison, Sandy P.; Kelley, Douglas I.; Prentice, I. Colin; Rabin, Sam S.; Archibald, Sally; Mouillot, Florent; Arnold, Steve R.; Artaxo, Paulo; Bachelet, Dominique; Ciais, Philippe; Forrest, Matthew; Friedlingstein, Pierre; Hickler, Thomas; Kaplan, Jed O.; Kloster, Silvia; Knorr, Wolfgang; Lasslop, Gitta; Li, Fang; Mangeon, Stephane; Melton, Joe R.; Meyn, Andrea; Sitch, Stephen; Spessa, Allan; van der Werf, Guido R.; Voulgarakis, Apostolos; Yue, Chao

    2016-06-01

    Biomass burning impacts vegetation dynamics, biogeochemical cycling, atmospheric chemistry, and climate, with sometimes deleterious socio-economic impacts. Under future climate projections it is often expected that the risk of wildfires will increase. Our ability to predict the magnitude and geographic pattern of future fire impacts rests on our ability to model fire regimes, using either well-founded empirical relationships or process-based models with good predictive skill. While a large variety of models exist today, it is still unclear which type of model or degree of complexity is required to model fire adequately at regional to global scales. This is the central question underpinning the creation of the Fire Model Intercomparison Project (FireMIP), an international initiative to compare and evaluate existing global fire models against benchmark data sets for present-day and historical conditions. In this paper we review how fires have been represented in fire-enabled dynamic global vegetation models (DGVMs) and give an overview of the current state of the art in fire-regime modelling. We indicate which challenges still remain in global fire modelling and stress the need for a comprehensive model evaluation and outline what lessons may be learned from FireMIP.

  15. Enabling a new Paradigm to Address Big Data and Open Science Challenges

    Science.gov (United States)

    Ramamurthy, Mohan; Fisher, Ward

    2017-04-01

    Data are not only the lifeblood of the geosciences but they have become the currency of the modern world in science and society. Rapid advances in computing, communi¬cations, and observational technologies — along with concomitant advances in high-resolution modeling, ensemble and coupled-systems predictions of the Earth system — are revolutionizing nearly every aspect of our field. Modern data volumes from high-resolution ensemble prediction/projection/simulation systems and next-generation remote-sensing systems like hyper-spectral satellite sensors and phased-array radars are staggering. For example, CMIP efforts alone will generate many petabytes of climate projection data for use in assessments of climate change. And NOAA's National Climatic Data Center projects that it will archive over 350 petabytes by 2030. For researchers and educators, this deluge and the increasing complexity of data brings challenges along with the opportunities for discovery and scientific breakthroughs. The potential for big data to transform the geosciences is enormous, but realizing the next frontier depends on effectively managing, analyzing, and exploiting these heterogeneous data sources, extracting knowledge and useful information from heterogeneous data sources in ways that were previously impossible, to enable discoveries and gain new insights. At the same time, there is a growing focus on the area of "Reproducibility or Replicability in Science" that has implications for Open Science. The advent of cloud computing has opened new avenues for not only addressing both big data and Open Science challenges to accelerate scientific discoveries. However, to successfully leverage the enormous potential of cloud technologies, it will require the data providers and the scientific communities to develop new paradigms to enable next-generation workflows and transform the conduct of science. Making data readily available is a necessary but not a sufficient condition. Data providers

  16. Coping with global environmental change, disasters and security. Threats, challenges, vulnerabilities and risks

    Energy Technology Data Exchange (ETDEWEB)

    Brauch, Hans Guenter [Freie Univ. Berlin (Germany). Dept. of Political and Social Sciences; UNU-EHS, Bonn (DE). College of Associated Scientists and Advisors (CASA); Oswald Spring, Ursula [National Univ. of Mexico, Cuernavaca (MX). Regional Multidisciplinary Research Centre (CRIM); Mesjasz, Czeslaw [Cracow Univ. of Exonomics (Poland). Faculty of Management; Grin, John [Amsterdam Univ. (Netherlands). Dept. of Political Science; Dutch Knowledge network for Systems Innovations and Transitions (KSI), Amsterdam (Netherlands); Kameri-Mbote, Patricia [Strathmore Univ., Nairobi (Kenya). Dept. of Law; International Environmental Law Research Centre, Nairobi (Kenya); Chourou, Bechir [Univ. of Tunis-Carthage, Hammam-Chatt (Tunisia); Dunay, Pal [Geneva Centre for Security Policy (Switzerland). International Training Course in Security Policy; Birkmann, Joern (eds.) [United Nations Univ. (UNU), Bonn (DE). Inst. for Environment and Human Security (EHS)

    2011-07-01

    This policy-focused Global Environmental and Human Security Handbook for the Anthropo-cene (GEHSHA) addresses new security threats, challenges, vulnerabilities and risks posed by global environmental change and disasters. In 6 forewords, 5 preface essays 95 peer reviewed chapcountries analyse in 10 parts concepts of military and political hard security and economic, social, environmental soft security with a regional focus on the Near East, North and Sub-Sahara Africa and Asia and on hazards in urban centres. The major focus is on coping with global environmental change: climate change, desertification, water, food and health and with hazards and strategies on social vulnerability and resilience building and scientific, international, regional and national political strategies, policies and measures including early warning of conflicts and hazards. The book proposes a political geo-ecology and discusses a 'Fourth Green Revolution' for the Anthropocene era of earth history. (orig.)

  17. DYNAMICS AND NEW CHALLENGES IN THE GLOBAL COMMODITY MARKET

    Directory of Open Access Journals (Sweden)

    MARIA CARTAS

    2015-12-01

    Full Text Available Global economy and particularly the world production of goods depends to a large extent on the supply of raw materials, of resource inputs extracted from the environment as well as an easy access to them. Commodities play an important part in the growth of global production and in the world trade in goods and services. The access to raw materials is vital for sustaining the productive capacity of the economy and also for satisfying domestic demand for industrial goods. On the other side, increasing demand for commodities and the need for assuring a sustainable supply pose great challenges on the world economy. The issue of raw materials supply represents a high - priority theme in the political agenda of the European Union. The Raw Materials Initiative launched in 2008 by the European Commission is based on three main pillars: - to ensure the access to raw materials on world market at undistorted conditions; - to foster sustainable supply of raw materials from European sources; - to reduce the EU's consumption of primary raw materials. (EC, 2008. To this end, EC has started to take action in order to ensure access to resources and avoid supply shortages. A great deal of attention is being paid to the study of recent developments in the global and particular commodity markets, taking into consideration fundamental aspects as supply concentration, governance of producing countries, the pressure of demand and its impact on prices, material's substitutability, stressing the role of resource consumption efficiency, recycling and substitution of vital raw materials and thus providing policy makers and industry with reliable information on how to efficiently manage resource inputs. This paper is dealing with the main developments which occurred during the past decade or so in the global commodity market, a major driver of the world economy, with particular reference to selected key -markets - as: aluminium, copper, nickel; cotton; corn, meat - swine

  18. High level radioactive waste (HLW) disposal a global challenge

    CERN Document Server

    PUSCH, R; NAKANO, M

    2011-01-01

    High Level Radioactive Waste (HLW) Disposal, A Global Challenge presents the most recent information on proposed methods of disposal for the most dangerous radioactive waste and for assessing their function from short- and long-term perspectives. It discusses new aspects of the disposal of such waste, especially HLW.The book is unique in the literature in making it clear that, due to tectonics and long-term changes in rock structure, rock can serve only as a ""mechanical support to the chemical apparatus"" and that effective containment of hazardous elements can only be managed by properly des

  19. Addressing Data Analysis Challenges in Gravitational Wave Searches Using the Particle Swarm Optimization Algorithm

    Science.gov (United States)

    Weerathunga, Thilina Shihan

    2017-08-01

    Gravitational waves are a fundamental prediction of Einstein's General Theory of Relativity. The first experimental proof of their existence was provided by the Nobel Prize winning discovery by Taylor and Hulse of orbital decay in a binary pulsar system. The first detection of gravitational waves incident on earth from an astrophysical source was announced in 2016 by the LIGO Scientific Collaboration, launching the new era of gravitational wave (GW) astronomy. The signal detected was from the merger of two black holes, which is an example of sources called Compact Binary Coalescences (CBCs). Data analysis strategies used in the search for CBC signals are derivatives of the Maximum-Likelihood (ML) method. The ML method applied to data from a network of geographically distributed GW detectors--called fully coherent network analysis--is currently the best approach for estimating source location and GW polarization waveforms. However, in the case of CBCs, especially for lower mass systems (O(1M solar masses)) such as double neutron star binaries, fully coherent network analysis is computationally expensive. The ML method requires locating the global maximum of the likelihood function over a nine dimensional parameter space, where the computation of the likelihood at each point requires correlations involving O(104) to O(106) samples between the data and the corresponding candidate signal waveform template. Approximations, such as semi-coherent coincidence searches, are currently used to circumvent the computational barrier but incur a concomitant loss in sensitivity. We explored the effectiveness of Particle Swarm Optimization (PSO), a well-known algorithm in the field of swarm intelligence, in addressing the fully coherent network analysis problem. As an example, we used a four-detector network consisting of the two LIGO detectors at Hanford and Livingston, Virgo and Kagra, all having initial LIGO noise power spectral densities, and show that PSO can locate the global

  20. Organization for rare diseases India (ORDI) - addressing the challenges and opportunities for the Indian rare diseases' community.

    Science.gov (United States)

    Rajasimha, Harsha Karur; Shirol, Prasannakumar Basayya; Ramamoorthy, Preveen; Hegde, Madhuri; Barde, Sangeeta; Chandru, Vijay; Ravinandan, M E; Ramchandran, Ramani; Haldar, Kasturi; Lin, Jimmy C; Babar, Imran A; Girisha, Katta M; Srinivasan, Sudha; Navaneetham, Duraiswamy; Battu, Rajani; Devarakonda, Rajashree; Kini, Usha; Vijayachandra, Kinnimulki; Verma, Ishwar C

    2014-08-13

    In order to address the unmet needs and create opportunities that benefit patients with rare disease in India, a group of volunteers created a not-for-profit organization named Organization for Rare Diseases India (ORDI; www.ordindia.org). ORDI plans to represent the collective voice and advocate the needs of patients with rare diseases and other stakeholders in India. The ORDI team members come from diverse backgrounds such as genetics, molecular diagnostics, drug development, bioinformatics, communications, information technology, patient advocacy and public service. ORDI builds on the lessons learned from numerous similar organizations in the USA, European Union and disease-specific rare disease foundations in India. In this review, we provide a background on the landscape of rare diseases and the organizations that are active in this area globally and in India. We discuss the unique challenges in tackling rare diseases in India, and highlight the unmet needs of the key stakeholders of rare diseases. Finally, we define the vision, mission, goals and objectives of ORDI, identify the key developments in the health care context in India and welcome community feedback and comments on our approach.

  1. Constraints and challenges in access to insulin: a global perspective.

    Science.gov (United States)

    Beran, David; Ewen, Margaret; Laing, Richard

    2016-03-01

    Substantial attention has been given to the issue of access to medicines for communicable diseases; however, access to essential medicines for diabetes, especially insulin, has had insufficient focus. Although insulin was discovered in 1921, the drug is unattainable to many globally, and this Review aims to highlight the range and complexity of factors that contribute to this unattainability. Manufacturers' selling prices of various insulin formulations and presentations, duties, taxes, mark-ups, and other supply chain costs affect the price of insulin and hence the drug's affordability to health systems and individuals. Unlike drugs for HIV and AIDS, the production of generic or biosimilar insulin has not had an effect on the overall market. Other factors contributing to poor availability of insulin include its quantification at the national level, in-country distribution, and determination of needs at lower levels of the health system. Although insulin is essential for the survival of people with type 1 diabetes and is needed for improved management of diabetes for some people with type 2 diabetes, very little has been done globally to address the issue of access, despite the UN's political commitment to address non-communicable diseases and ensure universal access to drugs for these disorders.

  2. U.S. Transportation Command Needs Further Improvements to Address Performance Concerns Over the Global Privately Owned Vehicle Contract 3

    Science.gov (United States)

    2016-02-03

    U A R Y 3 , 2 0 1 6 U.S. Transportation Command Needs Further Improvements to Address Performance Concerns Over the Global Privately Owned...USTRANSCOM) Global Privately Owned Vehicle Contract (GPC) III (HTC711-14-D-R025). Our objective was to determine whether USTRANSCOM contracting personnel...Concerns Over the Global Privately Owned Vehicle Contract III ii │ DODIG-2016-044 (Project No. D2015-D000CL-0091.000) Recommendations Table

  3. The Global Atmosphere Watch Programme: New Challenges and Opportunities

    Science.gov (United States)

    Terblanche, D. E.; Tarasova, O. A.

    2015-12-01

    The Global Atmosphere Watch Programme, one of the tree research Programmes of the World Meteorological Organization (WMO/GAW) is the only existing long-term international global programme that coordinates observations and analysis of atmospheric composition changes. The GAW Programme builds on a partnership of more than 100 countries. Within its 25 years of existence WMO/GAW has matured to the system that provides reliable long-term high quality observations in support of international policy making. WMO/GAW includes globally coordinated observational network, complemented by a comprehensive quality assurance system and capacity development. In spite of the fact that GAW has embraced the IGACO strategy (Integrated Global Atmospheric Chemistry Observations), the programme in its current form still has a strong observational bias. Future development of WMO/GAW requires the further evolution of the programme concept toward "science for services". New challenges call for the changes in the GAW station requirements and data managements, for new approaches to collaboration with the contributing networks and better involvement of the modelling community. The programme structure is evolving to streamline better to user requirements with the move from precipitation chemistry to total deposition and from near-real-time data delivery to applications (modeling) requiring such data delivery. The updated concept of GAW will include more cross-cutting applications. A new category of local station is introduced to help with the verification of some applications including those related to urban areas and the impacts of urban complexes regionally and globally. The evolution of the GAW Programme towards user driven cross-cutting applications provides a new opportunity to the National Meteorological and Hydrological Services in partnership with other science - based institutions to increase their relevance to society.

  4. Addressing challenges in combining GOES and LEO satellite products of the CONUS

    Science.gov (United States)

    Petersen, R. A.; Dworak, R.

    2012-12-01

    The challenges of transforming data from the next generation of satellites into information and products for the weather and science purposes presents a major challenge to both the research and applications communities. This will be especially difficult over land, where the process of integrating observations from multiple instruments and platforms in real time is complicated by the influence of the land surface on the observations themselves. In addition, effective merging of the mixture of time-continuous GEO and less frequent but higher spectral resolution LEO observations with other new surface-based observations will be essential and require new product processing strategies. The material shown in this presentation will begin to address some of these issues. It will describe results of efforts to inter-calibrate moisture products derived from existing GEO and LEO data sets over land designed 1) to identify and remove biases from the GOES moisture retrievals, 2) to determine the seasonally varying information content of the GOES relative to NWP model 'first guess' fields, 3) to determine the similarities and differences in error structures between GOES and AIRS retrievals, and 4) to determine the vertical structure of the errors in both systems. For example, comparisons have been made between GOES Total Precipitable Water (TPW) using the Li retrieval system (GOES-Li) and data from Raman Lidar (RL), Microwave Radiometer (MWR) and surface-based GPS-Met systems at the ARM CART site. The test showed for using one year of derived TPW products, the NWP model first guess (GFS) and GOES-Li products are wetter, however the GOES-Li beats the GFS in the warm season, especially in August when the NWP precipitation skill is least. During the warm season GOES-Li is noticeably better than GFS (which was too wet) during daytime. In addition, the GPS-Met data are best during the daytime, while the Ramon Lidar performs best at night. AIRS products were also evaluated for several

  5. Global scenarios for the energy industry: challenge and response

    Energy Technology Data Exchange (ETDEWEB)

    Kahane, A.

    1991-01-01

    Three areas of far reaching change that will affect the future of the energy industry are identified - geopolitical changes, such as the collapse of communist regimes in Eastern Europe and the Soviet Union, the relative decline of economic importance of the USA and the stimulus of European Community programmes; changes and difficulties in the international economy such as disagreement over trade and foreign direct investment; and thirdly, changing attitudes towards man's impact on the natural environment. These changes suggest two different images of the future, one called 'global mercantilism' and the other 'sustainable change'. In the first, the main global challenge is to deal with decline in the hegemonic position of the USA and Japan and the instability in international markets - the energy industry here faces new rules for business; in the 'sustainable world' the main challenge is to deal with common problems with implications for the redefining of the value of clean fuels and processes as well as substantial reconstruction of the energy industry. 10 figs.

  6. Food, Populations and Health — global Patterns and Challenges

    DEFF Research Database (Denmark)

    2016-01-01

    The present volume is based on presentations at a symposium at the Royal Danish Academy of Sciences and Letters in September 2014 with the title Food, Population and Health – global Patterns and Challenges. Food has played a fundamental role in the history of all societies over the World. Availab......The present volume is based on presentations at a symposium at the Royal Danish Academy of Sciences and Letters in September 2014 with the title Food, Population and Health – global Patterns and Challenges. Food has played a fundamental role in the history of all societies over the World...... spongiform encephalopathy and tuberculosis have been passed on from animals to humans through food. Larsson traces the Swedish outbreak of smallpox and dysentery in the 18th century and Revuelta-Eugercios discusses the promises of individual level data analysis on a mass basis as approach to socioeconomic...... have been as low as in nineteenth century Scandinavian low infant mortality regions. Gardarsdóttir demonstrates how increased breastfeeding in Iceland during 1850–1920 reduced infant mortality, but was still viewed with scepticism by many mothers. Based on the Dutch experience of famine 1944–45 Lumey...

  7. Cosmetic Surgery: Regulatory Challenges in a Global Beauty Market.

    Science.gov (United States)

    Griffiths, Danielle; Mullock, Alex

    2017-02-28

    The market for cosmetic surgery tourism is growing with an increase in people travelling abroad for cosmetic surgery. While the reasons for seeking cosmetic surgery abroad may vary the most common reason is financial, but does cheaper surgery abroad carry greater risks? We explore the risks of poorly regulated cosmetic surgery to society generally before discussing how harm might be magnified in the context of cosmetic tourism, where the demand for cheaper surgery drives the market and makes surgery accessible for increasing numbers of people. This contributes to the normalisation of surgical enhancement, creating unhealthy cultural pressure to undergo invasive and risky procedures in the name of beauty. In addressing the harms of poorly regulated surgery, a number of organisations purport to provide a register of safe and ethical plastic surgeons, yet this arguably achieves little and in the absence of improved regulation the risks are likely to grow as the global market expands to meet demand. While the evidence suggests that global regulation is needed, the paper concludes that since a global regulatory response is unlikely, more robust domestic regulation may be the best approach. While domestic regulation may increase the drive towards foreign providers it may also have a symbolic effect which will reduce this drive by making people more aware of the dangers of surgery, both to society and individual physical wellbeing.

  8. Academic Research Library as Broker in Addressing Interoperability Challenges for the Geosciences

    Science.gov (United States)

    Smith, P., II

    2015-12-01

    Data capture is an important process in the research lifecycle. Complete descriptive and representative information of the data or database is necessary during data collection whether in the field or in the research lab. The National Science Foundation's (NSF) Public Access Plan (2015) mandates the need for federally funded projects to make their research data more openly available. Developing, implementing, and integrating metadata workflows into to the research process of the data lifecycle facilitates improved data access while also addressing interoperability challenges for the geosciences such as data description and representation. Lack of metadata or data curation can contribute to (1) semantic, (2) ontology, and (3) data integration issues within and across disciplinary domains and projects. Some researchers of EarthCube funded projects have identified these issues as gaps. These gaps can contribute to interoperability data access, discovery, and integration issues between domain-specific and general data repositories. Academic Research Libraries have expertise in providing long-term discovery and access through the use of metadata standards and provision of access to research data, datasets, and publications via institutional repositories. Metadata crosswalks, open archival information systems (OAIS), trusted-repositories, data seal of approval, persistent URL, linking data, objects, resources, and publications in institutional repositories and digital content management systems are common components in the library discipline. These components contribute to a library perspective on data access and discovery that can benefit the geosciences. The USGS Community for Data Integration (CDI) has developed the Science Support Framework (SSF) for data management and integration within its community of practice for contribution to improved understanding of the Earth's physical and biological systems. The USGS CDI SSF can be used as a reference model to map to Earth

  9. Dublin Ireland: a city addressing challenging water supply, management, and governance issues

    Directory of Open Access Journals (Sweden)

    Mary Kelly-Quinn

    2014-12-01

    Full Text Available The population of Dublin City and its suburbs currently stands at 1.3 million and is projected to reach 2.1 million by 2022. There is pressure on its water supply system (inadequate catchment sources, ageing infrastructure including treatment facilities, and distribution network with little or no spare capacity despite Ireland's relatively high rainfall that is well distributed throughout the year; albeit the greatest rainfall occurs in the west and southwest and at some remove from Dublin. The current governance approach to addressing the projected water supply deficit relies heavily on a combination of identifying new supply sources to secure the long-term water supply needs of the city together with an intense drive toward achieving "demand-side" reduced usage and conservation targets in accordance with EU benchmarks for various individual and sectoral users. This potentially emerging crisis of water scarcity in Dublin, with drivers including population growth, greater industrial and institutional demands, migration, and climate change, has generated one of the most significant public water works projects proposed in Irish history, which is to abstract raw water from the Shannon River Basin in the midland region and, following treatment, pump it to a storage reservoir in a cut-away bog before piping to the Greater Dublin Area. The preparations for this scheme have brought to the forefront some longstanding Irish water resources governance issues and challenges. This provides a unique opportunity and imperative at this time to take a more comprehensive look at the decision-making process in this regard, one done in the context of new European and national policies requiring incorporation of integrated planning to sustain ecosystem services, water resources management, water services management, and flood defense principles, and one taking account of the current unprecedented state of flux in which water resources management institutions in

  10. Addressing challenges in bar-code scanning of large-volume infusion bags.

    Science.gov (United States)

    Raman, Kirthana; Heelon, Mark; Kerr, Gary; Higgins, Thomas L

    2011-08-01

    A hospital pharmacy's efforts to identify and address challenges with bedside scanning of bar codes on large-volume parenteral (LVP) infusion bags are described. Bar-code-assisted medication administration (BCMA) has been shown to reduce medication errors and improve patient safety. After the pilot implementation of a BCMA system and point-of-care scanning procedures at a medical center's intensive care unit, it was noted that nurses' attempted bedside scans of certain LVP bags for product identification purposes often were not successful. An investigation and root-cause analysis, including observation of nurses' scanning technique by a multidisciplinary team, determined that the scanning failures stemmed from the placement of two bar-code imprints-one with the product identification code and another, larger imprint with the expiration date and lot number-adjacently on the LVP bags. The nursing staff was educated on a modified scanning technique, which resulted in significantly improved success rates in the scanning of the most commonly used LVP bags. Representatives of the LVP bag manufacturer met with hospital staff to discuss the problem and corrective measures. As part of a subsequent infusion bag redesign, the manufacturer discontinued the use of the bar-code imprint implicated in the scanning failures. Failures in scanning LVP bags were traced to problematic placement of bar-code imprints on the bags. Interdisciplinary collaboration, consultation with the bag manufacturer, and education of the nursing and pharmacy staff resulted in a reduction in scanning failures and the manufacturer's removal of one of the bar codes from its LVP bags.

  11. Key challenges of offshore wind power: Three essays addressing public acceptance, stakeholder conflict, and wildlife impacts

    Science.gov (United States)

    Bates, Alison Waterbury

    Society is facing a pressing need to reduce greenhouse gas emissions to limit anthropogenic climate change, which has far reaching implications for humans and the environment. Transforming the energy infrastructure to carbon-free sources is one solution to curb greenhouse gas emissions, but this transformation has been slow to materialize in many places, such as the United States (U.S.). Offshore wind energy is one of the most promising renewable energy sources available, which can be deployed in large-scale developments in many parts of the world. Yet, offshore wind has faced many challenges, which are more social and regulatory than technical. This dissertation addresses social and regulatory issues surrounding offshore wind development through three stand-alone essays, which, in combination, address a decision-making framework of where to locate offshore wind turbines, by minimizing effects on people and wildlife. The challenges to offshore wind that are addressed by this dissertation include (1) understanding underlying factors that drive support for or opposition to offshore wind energy; (2) conflict with existing ocean uses and users; and (3) public concern and regulatory processes related to wildlife impacts. The first paper identifies unique factors that drive public opinion of proposed offshore wind projects in nearby coastal communities. Wind energy development on land has faced local opposition for reasons such as effects on cultural landscapes and wildlife, which can be instrumental in whether or not and the speed with which a project moves ahead toward completion. Factors leading to support for, or opposition to, offshore wind energy are not well known, particularly for developments that are near-shore and in-view of coastal communities. Results are presented from a survey of 699 residents (35.5% response rate) completed in 2013 in greater Atlantic City, New Jersey and coastal Delaware, United States, where near-shore wind demonstration projects had

  12. Addressing the local aspects of global change impacts on stream metabolism using frequency analysis tools.

    Science.gov (United States)

    Val, Jonatan; Pino, Rosa; Navarro, Enrique; Chinarro, David

    2016-11-01

    Global change, as a combination of climate change, human activities on watersheds and the river flow regulation, causes intense changes in hydrological cycles and, consequently, threatens the good ecological status of freshwater biological communities. This study addresses how and whether the combination of climatic drivers and local human impacts may alter the metabolism of freshwater communities. We identified a few factors modulating the natural water flow and quality in 25 point spread within the Ebro river Basin: waste water spills, industrial spills, reservoir discharges, water withdrawals, agricultural use, and the presence of riparian forests. We assessed their impacts on the freshwater metabolism as changes in the annual cycle of both gross primary production-GPP - and ecosystem respiration-ER -. For this purpose, daily data series were analyzed by continuous wavelet transformation, allowing for the assessment of the metabolic ecosystem Frequency Spectrum Patterns (FSPs). Changes in the behavior of ecosystem metabolism were strongly associated with local characteristics at each sampling point, however in 20 out of 25 studied points, changes in metabolic ecosystem FSP were related to climatic change events (the driest period of the last 140years). The changes in FSP indicate that severe impacts on how biological communities use carbon sources occur as a result of the human water management - too much focus on human needs - during intense climatic events. Results show that local factors, and specially the flow regulation, may modulate the impact of global change. As example those points exposed to a more intense anthropization showed a clear disruption - and even disappearance - of the annual FSP. This information may help managers to understand the action mechanisms of non-climatic factors at ecosystem level, leading to better management policies based on the promotion of ecosystem resilience. The method here presented may help on improving the calculation

  13. Addressing Challenges to Public Understanding of Science: Epistemic Cognition, Motivated Reasoning, and Conceptual Change

    Science.gov (United States)

    Sinatra, Gale M.; Kienhues, Dorothe; Hofer, Barbara K.

    2014-01-01

    Science is of critical importance to daily life in a knowledge society and has a significant influence on many everyday decisions. As scientific problems increase in their number and complexity, so do the challenges facing the public in understanding these issues. Our objective is to focus on 3 of those challenges: the challenge of reasoning about…

  14. Localizing the Global and Globalizing the Local: Opportunities and Challenges in Bali Island Tourism Development

    Directory of Open Access Journals (Sweden)

    I Nyoman Darma Putra

    2015-10-01

    Full Text Available AbstractIn September and October 2013, only one week apart,Bali hosted two global events in the upper class markettourism resort Nusa Dua. The first event was the MissWorld beauty pageant, and the other one was the APECSummit. Thousands of journalists from all over the worldcovered these events. From a tourism marketing point ofview, these two prestigious events helped Bali boost itspopularity through global mass media. Historically, sincethe early phase of its development, Bali’s tourism industryhas received many benefits from global forces initiallychanneled out through the Dutch colonial power in the firstdecade of the twentieth century and later through nationaland multinational corporations. The recent enlisting byUNESCO of Bali’s cultural landscape as a world heritagesite (2012 provides yet another great example of how Balicontinues to receive global endorsement by world institutions as a unique tourism destination. This paper discusesopportunities and challenges caused by globalizationand localization phenomena in the management of Bali’stourism island destination. Bali’s experiences provide aninteresting example of how global and local stakeholdersdevelop the island tourism in a sustainable manner whileat the same time continuing to preserve its local arts andculture as one of its main attractions. While there aremany examples how both forces contribute to numerousopportunities toward the development of Bali’s tourism,it is also true to state that impacts of globalization causesvarious forms of distraction for the island’s ability to takefull control of its vast move of development.

  15. Global Water Governance in the Context of Global and Multilevel Governance: Its Need, Form, and Challenges

    Directory of Open Access Journals (Sweden)

    Joyeeta Gupta

    2013-12-01

    Full Text Available To complement this Special Feature on global water governance, we focused on a generic challenge at the global level, namely, the degree to which water issues need to be dealt with in a centralized, concentrated, and hierarchical manner. We examined water ecosystem services and their impact on human well-being, the role of policies, indirect and direct drivers in influencing these services, and the administrative level(s at which the provision of services and potential trade-offs can be dealt with. We applied a politics of scale perspective to understand motivations for defining a problem at the global or local level and show that the multilevel approach to water governance is evolving and inevitable. We argue that a centralized overarching governance system for water is unlikely and possibly undesirable; however, there is a need for a high-level think tank and leadership to develop a cosmopolitan perspective to promote sustainable water development.

  16. OpenTopography: Addressing Big Data Challenges Using Cloud Computing, HPC, and Data Analytics

    Science.gov (United States)

    Crosby, C. J.; Nandigam, V.; Phan, M.; Youn, C.; Baru, C.; Arrowsmith, R.

    2014-12-01

    OpenTopography (OT) is a geoinformatics-based data facility initiated in 2009 for democratizing access to high-resolution topographic data, derived products, and tools. Hosted at the San Diego Supercomputer Center (SDSC), OT utilizes cyberinfrastructure, including large-scale data management, high-performance computing, and service-oriented architectures to provide efficient Web based access to large, high-resolution topographic datasets. OT collocates data with processing tools to enable users to quickly access custom data and derived products for their application. OT's ongoing R&D efforts aim to solve emerging technical challenges associated with exponential growth in data, higher order data products, as well as user base. Optimization of data management strategies can be informed by a comprehensive set of OT user access metrics that allows us to better understand usage patterns with respect to the data. By analyzing the spatiotemporal access patterns within the datasets, we can map areas of the data archive that are highly active (hot) versus the ones that are rarely accessed (cold). This enables us to architect a tiered storage environment consisting of high performance disk storage (SSD) for the hot areas and less expensive slower disk for the cold ones, thereby optimizing price to performance. From a compute perspective, OT is looking at cloud based solutions such as the Microsoft Azure platform to handle sudden increases in load. An OT virtual machine image in Microsoft's VM Depot can be invoked and deployed quickly in response to increased system demand. OT has also integrated SDSC HPC systems like the Gordon supercomputer into our infrastructure tier to enable compute intensive workloads like parallel computation of hydrologic routing on high resolution topography. This capability also allows OT to scale to HPC resources during high loads to meet user demand and provide more efficient processing. With a growing user base and maturing scientific user

  17. Novel developments in benthic modelling to address scientific and policy challenges

    Science.gov (United States)

    Lessin, Gennadi; Artioli, Yuri; Bruggeman, Jorn; Aldridge, John; Blackford, Jerry

    2016-04-01

    Understanding the role of benthic systems in supporting, regulating and providing marine ecosystem services requires better understanding of their functioning and their response and resilience to stressors. Novel observational methods for the investigation of dynamics of benthic-pelagic coupling in shelf seas are being developed and new data is being collected. Therefore there is an increasing demand for robust representation of benthic processes in marine biogeochemical and ecosystem models, which would improve our understanding of whole systems and benthic-pelagic coupling, rather than act as mere closure terms for pelagic models. However, for several decades development of benthic models has lagged behind their pelagic counterparts. To address contemporary scientific, policy and societal challenges, the biogeochemical and ecological model ERSEM (European Regional Seas Ecosystem Model), including its benthic sub-model, was recently recoded in a scalable and modular format adopting the approach of FABM (Framework for Aquatic Biogeochemical Models). Within the Shelf Sea Biogeochemistry research programme, a series of additional processes have been included, such as a sedimentary carbonate system, a resuspendable fluff layer, and the simulation of advective sediments. It was shown that the inclusion of these processes changes the dynamics of benthic-pelagic fluxes as well as modifying the benthic food web. Comparison of model results with in-situ data demonstrated a general improvement of model performance and highlighted the importance of the benthic system in overall ecosystem dynamics. As an example, our simulations have shown that inclusion of a resuspendable fluff layer facilitates regeneration of inorganic nutrients in the water column due to degradation of resuspended organic material by pelagic bacteria. Moreover, the composition of fluff was found to be important for trophic interactions, and therefore indirectly affects benthic community composition. Where

  18. Technology solutions for a global business. Opportunities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Warren, Tim

    2000-07-01

    Shell's relationship with Norway goes back a long way and is very important to our future as well, as is evident from this presentation, which describes some of the pressures on a global energy business like Shell. It also deals with the fundamental importance of technology in the way we respond to those pressures. The power of innovation, and of partnerships, in keeping us at the front of the wave and, using our experiences, it is described how we at Shell deal with these issues. It also gives some examples of the benefits that have come out of our partnerships here in Norway, and the challenges and opportunities confronting those partnerships in the future.

  19. Family health nursing: a response to the global health challenges.

    Science.gov (United States)

    Martin, Paul; Duffy, Tim; Johnston, Brian; Banks, Pauline; Harkess-Murphy, Eileen; Martin, Colin R

    2013-02-01

    The European Family Health Nursing Project is a revitalized World Health Organization initiative led by the University of the West of Scotland. Partner countries include Armenia, Austria, Germany, Italy, Poland, Portugal, Romania, Slovenia, and Spain. European Union Lifelong Learning funding was received in 2011 to facilitate a consistency of approach in the development of a definition of family health nursing, required core competencies and capabilities, and consequent education and training requirements. Global health challenges have informed the development of the project: increasingly aging populations, the increasing incidence in noncommunicable diseases that are currently the main cause of death, and the significant progress made in the way health systems have developed to meet the demands in relation to access and equality of health services. Governments and policy makers should develop a health workforce based on the principles of teamwork and interdisciplinarity while recognizing the core contribution of the "specialist generalist" role in the primary care setting.

  20. Global and environmental monitoring: the challenge to educators

    Science.gov (United States)

    Beek, K. J.; van Gils, H. A. M. J.

    The public's increasing concern about environmental degradation is creating new demands for environmental monitoring and appropriate interventions to reduce or eliminate the sources and causes of environmental damage. We have two invaluable tools for addressing environmental problems: satellite remote sensing for collecting the essential data, and geographic information systems (GIS) for processing and evaluating these data and modelling the effects of various environmental management options. As educators, we have a special challenge to train the scientists who will be responsible for carrying out this work. An interdisciplinary approach is required to understand the multiple causes and effects of environmental problems, and special skills are needed to convey this information to the government agencies and individuals who can implement corrective measures. We have been quite successful at ITC in integrating remote sensing and GIS for environmental monitoring within our research and education programmes. Our present (and future) efforts are directed towards reinforcing the interdisciplinary approach considered essential in environmental management.

  1. Modelling Freshwater Resources at the Global Scale: Challenges and Prospects

    Science.gov (United States)

    Doll, Petra; Douville, Herve; Guntner, Andreas; Schmied, Hannes Muller; Wada, Yoshihide

    2015-01-01

    Quantification of spatially and temporally resolved water flows and water storage variations for all land areas of the globe is required to assess water resources, water scarcity and flood hazards, and to understand the Earth system. This quantification is done with the help of global hydrological models (GHMs). What are the challenges and prospects in the development and application of GHMs? Seven important challenges are presented. (1) Data scarcity makes quantification of human water use difficult even though significant progress has been achieved in the last decade. (2) Uncertainty of meteorological input data strongly affects model outputs. (3) The reaction of vegetation to changing climate and CO2 concentrations is uncertain and not taken into account in most GHMs that serve to estimate climate change impacts. (4) Reasons for discrepant responses of GHMs to changing climate have yet to be identified. (5) More accurate estimates of monthly time series of water availability and use are needed to provide good indicators of water scarcity. (6) Integration of gradient-based groundwater modelling into GHMs is necessary for a better simulation of groundwater-surface water interactions and capillary rise. (7) Detection and attribution of human interference with freshwater systems by using GHMs are constrained by data of insufficient quality but also GHM uncertainty itself. Regarding prospects for progress, we propose to decrease the uncertainty of GHM output by making better use of in situ and remotely sensed observations of output variables such as river discharge or total water storage variations by multi-criteria validation, calibration or data assimilation. Finally, we present an initiative that works towards the vision of hyper resolution global hydrological modelling where GHM outputs would be provided at a 1-km resolution with reasonable accuracy.

  2. Modelling Freshwater Resources at the Global Scale: Challenges and Prospects

    Science.gov (United States)

    Döll, Petra; Douville, Hervé; Güntner, Andreas; Müller Schmied, Hannes; Wada, Yoshihide

    2016-03-01

    Quantification of spatially and temporally resolved water flows and water storage variations for all land areas of the globe is required to assess water resources, water scarcity and flood hazards, and to understand the Earth system. This quantification is done with the help of global hydrological models (GHMs). What are the challenges and prospects in the development and application of GHMs? Seven important challenges are presented. (1) Data scarcity makes quantification of human water use difficult even though significant progress has been achieved in the last decade. (2) Uncertainty of meteorological input data strongly affects model outputs. (3) The reaction of vegetation to changing climate and CO2 concentrations is uncertain and not taken into account in most GHMs that serve to estimate climate change impacts. (4) Reasons for discrepant responses of GHMs to changing climate have yet to be identified. (5) More accurate estimates of monthly time series of water availability and use are needed to provide good indicators of water scarcity. (6) Integration of gradient-based groundwater modelling into GHMs is necessary for a better simulation of groundwater-surface water interactions and capillary rise. (7) Detection and attribution of human interference with freshwater systems by using GHMs are constrained by data of insufficient quality but also GHM uncertainty itself. Regarding prospects for progress, we propose to decrease the uncertainty of GHM output by making better use of in situ and remotely sensed observations of output variables such as river discharge or total water storage variations by multi-criteria validation, calibration or data assimilation. Finally, we present an initiative that works towards the vision of hyperresolution global hydrological modelling where GHM outputs would be provided at a 1-km resolution with reasonable accuracy.

  3. Modelling Freshwater Resources at the Global Scale: Challenges and Prospects

    Science.gov (United States)

    Doll, Petra; Douville, Herve; Guntner, Andreas; Schmied, Hannes Muller; Wada, Yoshihide

    2015-01-01

    Quantification of spatially and temporally resolved water flows and water storage variations for all land areas of the globe is required to assess water resources, water scarcity and flood hazards, and to understand the Earth system. This quantification is done with the help of global hydrological models (GHMs). What are the challenges and prospects in the development and application of GHMs? Seven important challenges are presented. (1) Data scarcity makes quantification of human water use difficult even though significant progress has been achieved in the last decade. (2) Uncertainty of meteorological input data strongly affects model outputs. (3) The reaction of vegetation to changing climate and CO2 concentrations is uncertain and not taken into account in most GHMs that serve to estimate climate change impacts. (4) Reasons for discrepant responses of GHMs to changing climate have yet to be identified. (5) More accurate estimates of monthly time series of water availability and use are needed to provide good indicators of water scarcity. (6) Integration of gradient-based groundwater modelling into GHMs is necessary for a better simulation of groundwater-surface water interactions and capillary rise. (7) Detection and attribution of human interference with freshwater systems by using GHMs are constrained by data of insufficient quality but also GHM uncertainty itself. Regarding prospects for progress, we propose to decrease the uncertainty of GHM output by making better use of in situ and remotely sensed observations of output variables such as river discharge or total water storage variations by multi-criteria validation, calibration or data assimilation. Finally, we present an initiative that works towards the vision of hyper resolution global hydrological modelling where GHM outputs would be provided at a 1-km resolution with reasonable accuracy.

  4. Networking of integrated pest management: A powerful approach to address common challenges in agriculture

    DEFF Research Database (Denmark)

    Lamichhane, Jay Ram; Aubertot, J-N; Begg, Graham;

    2016-01-01

    of designing effective pest management strategies, which rely less heavily on the use of conventional pesticides, is another external challenge. Internal challenges include organizational aspects such as decreasing trend in budget allocated to IPM research, increasing scarcity of human expertise, lack...... networking experiences in Europe emphasizing how IPM research, implementation and adoption in Europe may benefit from a broader level networking....

  5. Addressing Energy System Modelling Challenges: The Contribution of the Open Energy Modelling Framework (oemof)

    DEFF Research Database (Denmark)

    Hilpert, Simon; Günther, Stephan; Kaldemeyer, Cord

    2017-01-01

    The process of modelling energy systems is accompanied by challenges inherently connected with mathematical modelling. However, due to modern realities in the 21st century, existing challenges are gaining in magnitude and are supplemented with new ones. Modellers are confronted with a rising comp...

  6. Strategies to Address English Language Writing Challenges Faced by International Graduate Students in the US

    Science.gov (United States)

    Ravichandran, Swathi; Kretovics, Mark; Kirby, Kara; Ghosh, Ankita

    2017-01-01

    Since 2000, there has been a 72% increase in the number of international students attending US institutions of higher education. The increase, specifically of international graduate students, has brought to light the writing challenges experienced by this population of students. This study explored specific writing challenges experienced by…

  7. Global challenges of graduate level Ayurvedic education: A survey.

    Science.gov (United States)

    Patwardhan, Kishor; Gehlot, Sangeeta; Singh, Girish; Rathore, H C S

    2010-01-01

    In the present day scenario, Ayurveda is globally being perceived in several contradictory ways. Poor quality of Ayurveda graduates produced as a result of poorly structured and poorly regulated education system is at least one of the important factors responsible for this scenario. The present study was carried out to evaluate the 'Global challenges of graduate level Ayurvedic education' and is based on the responses of Ayurvedic students and Ayurvedic teachers from various educational institutions of India to a methodically validated questionnaire. As the study indicates, the poor standard of Ayurvedic education in India is definitely a cause of concern. The curriculum of Bachelor of Ayurvedic Medicine and Surgery (BAMS) course of studies is required to be reviewed and restructured. The syllabi are required to be updated with certain relevant topics like laws governing the intellectual property rights, basic procedures of standardization of medicinal products, fundamental methods of evaluating the toxicity of the medicinal products, essentials of healthcare management and the basics of cultivation and marketing of medicinal plants. Furthermore, the study suggests that the Ayurvedic academicians are required to be trained in standard methods of research and documentation skills, and the educational institutions are required to be encouraged to contribute their share in building up the evidence base for Ayurveda in the form of quality education and research.

  8. The Challenges of Home Enteral Tube Feeding: A Global Perspective

    Directory of Open Access Journals (Sweden)

    Omorogieva Ojo

    2015-04-01

    Full Text Available The aim of this review is to provide a global perspective of Home Enteral Tube Feeding (HETF and to outline some of the challenges of home enteral nutrition (HEN provisions. It is well established that the number of patients on HETF is on the increase worldwide due to advances in technology, development of percutaneous endoscopic gastrostomy techniques, and the shift in care provisions from acute to community settings. While the significance of home enteral nutrition in meeting the nutritional requirements of patients with poor swallowing reflexes and those with poor nutritional status is not in doubt, differences exist in terms of funding, standards, management approaches and the level of infrastructural development across the world. Strategies for alleviating some of the challenges militating against the effective delivery of HETF including the development of national and international standards, guidelines and policies for HETF, increased awareness and funding by government at all levels were discussed. Others, including development of HEN services, which should create the enabling environment for multidisciplinary team work, clinical audit and research, recruitment and retention of specialist staff, and improvement in patient outcomes have been outlined. However, more research is required to fully establish the cost effectiveness of the HEN service especially in developing countries and to compare the organization of HEN service between developing and developed countries.

  9. Eliminating Iodine Deficiency in China: Achievements, Challenges and Global Implications

    Science.gov (United States)

    Sun, Dianjun; Codling, Karen; Chang, Suying; Zhang, Shubin; Shen, Hongmei; Su, Xiaohui; Chen, Zupei; Scherpbier, Robert W.; Yan, Jun

    2017-01-01

    The prevention of iodine deficiency through salt iodization has been recognized as a global success story, and China stands at the forefront of this achievement with one of the most successful programs in the world. High level political commitment, national mandatory legislation, a state-managed edible salt industry and a complex and highly sophisticated surveillance system have facilitated the success of the program. Challenges have arisen however, including: (i) concern that adequate iodine status in pregnant women cannot be achieved without causing above adequate iodine intakes in children; (ii) declining iodine intake as a result of reductions in salt consumption and increased consumption of processed foods, which may not be made with iodized salt; (iii) the existence of areas with high iodine content in the water; and (iv) declines in household use of iodized salt due to concerns about excess iodine intake and thyroid disease. This article reviews the achievements and challenges of the Chinese Iodine Deficiency Disorders (IDD) Elimination Program and reflects on lessons learned and implications for other national salt iodization programs. PMID:28379180

  10. The challenges of home enteral tube feeding: a global perspective.

    Science.gov (United States)

    Ojo, Omorogieva

    2015-04-08

    The aim of this review is to provide a global perspective of Home Enteral Tube Feeding (HETF) and to outline some of the challenges of home enteral nutrition (HEN) provisions. It is well established that the number of patients on HETF is on the increase worldwide due to advances in technology, development of percutaneous endoscopic gastrostomy techniques, and the shift in care provisions from acute to community settings. While the significance of home enteral nutrition in meeting the nutritional requirements of patients with poor swallowing reflexes and those with poor nutritional status is not in doubt, differences exist in terms of funding, standards, management approaches and the level of infrastructural development across the world. Strategies for alleviating some of the challenges militating against the effective delivery of HETF including the development of national and international standards, guidelines and policies for HETF, increased awareness and funding by government at all levels were discussed. Others, including development of HEN services, which should create the enabling environment for multidisciplinary team work, clinical audit and research, recruitment and retention of specialist staff, and improvement in patient outcomes have been outlined. However, more research is required to fully establish the cost effectiveness of the HEN service especially in developing countries and to compare the organization of HEN service between developing and developed countries.

  11. Adapting to Symptoms of Global Warming Rather Than Addressing the Cause

    OpenAIRE

    Cairns, John

    2006-01-01

    In recent years, global warming has been ignored and scientists producing evidence supporting this hypothesis have been denigrated and even investigated. However, as irrefutable evidence showing that global warming was a reality mounted, the message shifted to global warming may be occurring, but it is not caused by human activity. Now the message is shifting again, and humankind I been told to adapt to global warming instead of making an effort to reverse it.

  12. Hyperresolution Global Land Surface Modeling: Meeting a Grand Challenge for Monitoring Earth's Terrestrial Water

    Science.gov (United States)

    Wood, Eric F.; Roundy, Joshua K.; Troy, Tara J.; van Beek, L. P. H.; Bierkens, Marc F. P.; 4 Blyth, Eleanor; de Roo, Ad; Doell. Petra; Ek, Mike; Famiglietti, James; Gochis, David; van de Giesen, Nick; Houser, Paul; Jaffe, Peter R.; Kollet, Stefan; Lehner, Bernhard; Lettenmaier, Dennis P.; Peters-Lidard, Christa; Sivpalan, Murugesu; Sheffield, Justin; Wade, Andrew; Whitehead, Paul

    2011-01-01

    Monitoring Earth's terrestrial water conditions is critically important to many hydrological applications such as global food production; assessing water resources sustainability; and flood, drought, and climate change prediction. These needs have motivated the development of pilot monitoring and prediction systems for terrestrial hydrologic and vegetative states, but to date only at the rather coarse spatial resolutions (approx.10-100 km) over continental to global domains. Adequately addressing critical water cycle science questions and applications requires systems that are implemented globally at much higher resolutions, on the order of 1 km, resolutions referred to as hyperresolution in the context of global land surface models. This opinion paper sets forth the needs and benefits for a system that would monitor and predict the Earth's terrestrial water, energy, and biogeochemical cycles. We discuss six major challenges in developing a system: improved representation of surface-subsurface interactions due to fine-scale topography and vegetation; improved representation of land-atmospheric interactions and resulting spatial information on soil moisture and evapotranspiration; inclusion of water quality as part of the biogeochemical cycle; representation of human impacts from water management; utilizing massively parallel computer systems and recent computational advances in solving hyperresolution models that will have up to 10(exp 9) unknowns; and developing the required in situ and remote sensing global data sets. We deem the development of a global hyperresolution model for monitoring the terrestrial water, energy, and biogeochemical cycles a grand challenge to the community, and we call upon the international hydrologic community and the hydrological science support infrastructure to endorse the effort.

  13. A framework for addressing implementation gap in global drowning prevention interventions: experiences from Bangladesh.

    Science.gov (United States)

    Hyder, Adnan A; Alonge, Olakunle; He, Siran; Wadhwaniya, Shirin; Rahman, Fazlur; El Arifeen, Shams

    2014-12-01

    Drowning is the commonest cause of injury-related deaths among under-five children worldwide, and 95% of deaths occur in low- and middle-income countries (LMICs) where there are implementation gaps in the drowning prevention interventions. This article reviews common interventions for drowning prevention, introduces a framework for effective implementation of such interventions, and describes the Saving of Lives from Drowning (SoLiD) Project in Bangladesh, which is based on this framework. A review of the systematic reviews on drowning interventions was conducted, and original research articles were pulled and summarized into broad prevention categories. The implementation framework builds upon two existing frameworks and categorizes the implementing process for drowning prevention interventions into four phases: planning, engaging, executing, and evaluating. Eleven key characteristics are mapped in these phases. The framework was applied to drowning prevention projects that have been undertaken in some LMICs to illustrate major challenges to implementation. The implementation process for the SoLiD Project in Bangladesh is used as an example to illustrate the practical utilization of the framework. Drowning interventions, such as pool fencing and covering of water hazards, are effective in high-income countries; however, most of these interventions have not been tested in LMICs. The critical components of the four phases of implementing drowning prevention interventions may include: (i) planning-global funding, political will, scale, sustainability, and capacity building; (ii) engaging-coordination, involvement of appropriate individuals; (iii) executing-focused action, multisectoral actions, quality of execution; and (iv) evaluating-rigorous monitoring and evaluation. Some of the challenges to implementing drowning prevention interventions in LMICs include insufficient funds, lack of technical capacity, and limited coordination among stakeholders and implementers

  14. A Holistic Approach towards Information and Communication Technology (ICT) for Addressing Education Challenges in Asia and the Pacific

    Science.gov (United States)

    Ra, Sungsup; Chin, Brian; Lim, Cher Ping

    2016-01-01

    Information and Communication Technology (ICT) offers opportunities for governments to address key education challenges of quality, equity, and efficiency. While governments and educational institutions in developed countries may have taken up these opportunities, many developing countries in Asia and the Pacific region have often missed them out.…

  15. A Holistic Approach towards Information and Communication Technology (ICT) for Addressing Education Challenges in Asia and the Pacific

    Science.gov (United States)

    Ra, Sungsup; Chin, Brian; Lim, Cher Ping

    2016-01-01

    Information and Communication Technology (ICT) offers opportunities for governments to address key education challenges of quality, equity, and efficiency. While governments and educational institutions in developed countries may have taken up these opportunities, many developing countries in Asia and the Pacific region have often missed them out.…

  16. Exploring a Community of Practice Model for Professional Development to Address Challenges to Classroom Practices in Early Childhood

    Science.gov (United States)

    Christ, Tanya; Wang, X. Christine

    2013-01-01

    This study explored whether or not, and how, an on-site and research-teacher community of practice model for professional development addressed the challenges to classroom practices in a Head Start program. Data sources included interviews with teachers, videos of planning and teaching sessions, and the researchers' fieldwork log and…

  17. Addressing the implementation gap in global road safety: exploring features of an effective response and introducing a 10-country program.

    Science.gov (United States)

    Hyder, Adnan A; Allen, Katharine A; Di Pietro, Gayle; Adriazola, Claudia A; Sobel, Rochelle; Larson, Kelly; Peden, Margie

    2012-06-01

    Yearly, more than 1.2 million people are killed by road traffic injuries (RTIs) around the globe, and another 20 to 50 million are injured. The global burden of RTIs is predicted to rise. We explored the need for concerted action for global road safety and propose characteristics of an effective response to the gap in addressing RTIs. We propose that a successful response includes domains such as strong political will, capacity building, use of evidence-based interventions, rigorous evaluation, increased global funding, multisectoral action, and sustainability. We also present a case study of the global Road Safety in 10 Countries project, which is a new, 5-year, multipartner initiative to address the burden of RTIs in 10 low- and middle-income countries.

  18. F-35 Joint Strike Fighter: Assessment Needed to Address Affordability Challenges

    Science.gov (United States)

    2015-04-01

    Percent of Labor Hours Spent on Scrap, Rework , and Repair for the F-35 Joint Strike Fighter 20 Figure 8: Average Number of F-35 Joint Strike Fighter...engine failure, and a higher than expected amount of test point growth largely to address software rework , over the past year, delayed key test...percent growth in mission system software test points for the year— largely to address software rework that might be needed—officials from the

  19. Can The Implementation Of E-Learning Technologies Help To Address Learning Challenges? Evidence From A Small Island University

    Directory of Open Access Journals (Sweden)

    Harshana Kasseeah

    2012-06-01

    Full Text Available This paper tries to explore the different ways in which online learning platforms can be used to address learning challenges for students at the University of Mauritius. The main challenges identified were in the form of large number of students in class, the lecturer being unable to give individual attention to each student and the inability to cover all material in the given time frame. Themain problems encountered by students were in the form of inability to ask questions due to the large class size, lack of interaction with the lecturer and in some cases the lack of supplementary material. Findings indicate that online learning platforms can indeed be used to address learning challenges so that the online learning platforms supplement and complement traditional face-to-face lectures.

  20. Improvement of GVSRM with Addressing the Interoperability Issues in Global Village

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Mollahoseini Ardakani

    2014-10-01

    Full Text Available In today's globally networked environment, enterprises need collaborating using Information Technology (IT and other tools to succeed in this dynamic and heterogeneous business environment. The Global Village Services Reference Model (GVSRM is a model based on SOSA (Service Oriented Strategies and Architectures ontology for global village services realization. In this model, three architectural abstraction layers have been considered for global village: ‘infrastructure for global village services’, ‘global village services provisioning’, and ‘using global village services’. Despite of relative completeness of this model, one of its obvious shortcomings is lack of attention to the crucial issue of interoperability in the global village. Based on this model, the grid of global village is comprised of VHGs (Virtual Holding Governance. The VHG is a temporary, scalable, dynamic cluster/association comprising of existing or newly service provider organizations which its aim is satisfying the requirements of global village actors through electronic processes. In this paper, we will propose a federated approach for interoperability among the VHGs of the global village and then improve the GVSRM by adding the corresponding interoperability components to it.

  1. Military Cooperation Frameworks: Effective Models to Address Transnational Security Challenges of the Asia-Pacific Region

    Science.gov (United States)

    2011-05-04

    197* (10) Sri Lanka 204* (12) Oceania American Samoa 22* (6) Australia 117* (11) Cook Islands 19* (4) Fiji 72* (8) Guam 24* (8) Kiribati...evolving security challenges. Issues such as terrorism, proliferation of weapons of mass destruction, impacts of climate change , and the ever...impacts of climate change , and the ever-growing competition for valuable natural resources are a few of the these challenges. As an integral part

  2. THE EUROPEAN UNION AS A GLOBAL PLAYER: PROSPECTS AND CHALLENGES

    Directory of Open Access Journals (Sweden)

    Lazar Comanescu

    2002-07-01

    Full Text Available Strengthening the external action of the Union has emerged as a powerful expectation shared both by a large majority of members of the Convention on the future of Europe, and more significantly by public opinion when it has been consulted on this issue. Although there is a consensual desire for Europe to speak with a stronger voice in global affairs, the ways and means to achieve this objective still divide those called to clarify the path to be followed. The European Union is already a significant presence in world politics by its considerable share in the international trade, or its dominant contribution to development aid. Many criticise on the other hand the lack of consistency in the more classical dimensions of foreign policy, or the lack of credibility in the capacity to act attributed to the absence of defence capabilities. Such concerns are currently addressed in the larger debate on the future of Europe, either within the dedicated framework, the European Convention convened to design the future of the EU, or outside the Convention, both among politicians and academics. It is generally considered and accepted that Europe will gain in political influence once the unification of the continent is completed, i.e. the current enlargement objectives are achieved. It goes without saying that devising and making operational appropriate instruments and capacities to act coherently outside its borders are a necessity as well. Institutional guarantees that Europe could in the future continue to influence the course of events in world affairs are becoming imperative. This article will explore some of the proposals in that sense. It will also address the place for Romania as a future EU member state in the new architecture of Europe and its possible contribution to the Common Foreign and Security Policy.

  3. State - Level Regulation's Effectiveness in Addressing Global Climate Change and Promoting Solar Energy Deployment

    Science.gov (United States)

    Peterman, Carla Joy

    Paper 1, Local Solutions to Global Problems: Climate Change Policies and Regulatory Jurisdiction, considers the efficacy of various types of environmental regulations when they are applied locally to pollutants whose damages extend beyond the jurisdiction of the local regulators. Local regulations of a global pollutant may be ineffective if producers and consumers can avoid them by transacting outside the reach of the local regulator. In many cases, this may involve the physical relocation of the economic activity, a problem often referred to as "leakage." This paper highlights another way in which local policies can be circumvented: through the shuffling of who buys from whom. The paper maintains that the problems of reshuffling are exacerbated when the options for compliance with the regulations are more flexible. Numerical analyses is presented demonstrating that several proposed policies to limit greenhouse gas emissions from the California electricity sector may have very little effect on carbon emissions if they are applied only within that state. Paper 1 concludes that although local subsidies for energy efficiency, renewable electricity, and transportation biofuels constitute attempts to pick technology winners, they may be the only mechanisms that local jurisdictions, acting alone, have at their disposal to address climate change. Paper 2, Pass-Through of Solar PV Incentives to Consumers: The Early Years of California's Solar PV Incentives, examines the pass through of incentives to California solar PV system owners. The full post-subsidy price consumers pay for solar power is a key metric of the success of solar PV incentive programs and of overall PV market performance. This study examines the early years of California's most recent wave of distributed solar PV incentives (2000-2008) to determine the pass-through of incentives. Examination of this period is both intellectually and pragmatically important due to the high level of incentives provided and

  4. Big Data Challenges in Global Seismic 'Adjoint Tomography' (Invited)

    Science.gov (United States)

    Tromp, J.; Bozdag, E.; Krischer, L.; Lefebvre, M.; Lei, W.; Smith, J.

    2013-12-01

    The challenge of imaging Earth's interior on a global scale is closely linked to the challenge of handling large data sets. The related iterative workflow involves five distinct phases, namely, 1) data gathering and culling, 2) synthetic seismogram calculations, 3) pre-processing (time-series analysis and time-window selection), 4) data assimilation and adjoint calculations, 5) post-processing (pre-conditioning, regularization, model update). In order to implement this workflow on modern high-performance computing systems, a new seismic data format is being developed. The Adaptable Seismic Data Format (ASDF) is designed to replace currently used data formats with a more flexible format that allows for fast parallel I/O. The metadata is divided into abstract categories, such as "source" and "receiver", along with provenance information for complete reproducibility. The structure of ASDF is designed keeping in mind three distinct applications: earthquake seismology, seismic interferometry, and exploration seismology. Existing time-series analysis tool kits, such as SAC and ObsPy, can be easily interfaced with ASDF so that seismologists can use robust, previously developed software packages. ASDF accommodates an automated, efficient workflow for global adjoint tomography. Manually managing the large number of simulations associated with the workflow can rapidly become a burden, especially with increasing numbers of earthquakes and stations. Therefore, it is of importance to investigate the possibility of automating the entire workflow. Scientific Workflow Management Software (SWfMS) allows users to execute workflows almost routinely. SWfMS provides additional advantages. In particular, it is possible to group independent simulations in a single job to fit the available computational resources. They also give a basic level of fault resilience as the workflow can be resumed at the correct state preceding a failure. Some of the best candidates for our particular workflow

  5. Mixed Methods Research Strategies with Deaf People: Linguistic and Cultural Challenges Addressed

    Science.gov (United States)

    Wilson, Amy T.; Winiarczyk, Rowena E.

    2014-01-01

    Deaf people, members of a complex global language minority, have been excluded from positions of power in the field of humanitarian aid and development assistance, as well as from playing a significant role in the conduct of research that affects their lives. Deaf people rarely lead or participate as researchers in studies about their own…

  6. Mixed Methods Research Strategies with Deaf People: Linguistic and Cultural Challenges Addressed

    Science.gov (United States)

    Wilson, Amy T.; Winiarczyk, Rowena E.

    2014-01-01

    Deaf people, members of a complex global language minority, have been excluded from positions of power in the field of humanitarian aid and development assistance, as well as from playing a significant role in the conduct of research that affects their lives. Deaf people rarely lead or participate as researchers in studies about their own…

  7. A complex system approach to address world challenges in food and agriculture

    NARCIS (Netherlands)

    Mil, van H.G.J.; Foegeding, E.A.; Windhab, E.J.; Perrot, N.; Linden, van der E.

    2014-01-01

    The quality and amount of the world food supply is crucial to the well-being of every human on the planet in the basic sense that we need food to live. It also has a profound impact on world economy, international trade, and global political stability. The choice of land used for agriculture, and th

  8. A multifaceted 'omics' approach for addressing the challenge of antimicrobial resistance

    NARCIS (Netherlands)

    Cohen, Asi; Bont, LJ; Engelhard, Dan; Moore, Edward; Fernandez, David; Kreisberg-Greenblatt, Racheli; Oved, Kfir; Eden, Eran; Hays, John P.

    2015-01-01

    The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagno

  9. EMERGING INFECTIOUS DISEASES. Actions Needed to Address the Challenges of Responding to Zika Virus Disease Outbreaks

    Science.gov (United States)

    2017-05-01

    required urgent and coordinated research.12 The Secretary of Health and Human Services...technical mechanism is required to manage the global response. However, the Zika virus and associated health outcomes remain a significant public health ...associated adverse health outcomes. Most of the 5,197 Zika virus disease cases reported by April 5, 2017 in the United States were associated with

  10. An assessment of open source promotion in addressing ICT acceptance challenges in Tanzania

    CSIR Research Space (South Africa)

    Kinyondo, J

    2012-05-01

    Full Text Available . Worldwide Open Source (OS) is regarded as a technology that could foster and support ICT development, due to various factors such as cost of adoption. Several OS communities have been formed to create awareness of OS and the potential OS has to address ICT...

  11. Addressing Wife Abuse in Mexican Immigrant Couples: Challenges for Family Social Workers

    Science.gov (United States)

    Hancock, Tina

    2006-01-01

    This article addresses wife abuse in undocumented Mexican immigrant couples and suggests an ecosystems treatment approach that takes into consideration the structural forces of oppression and discrimination on abusive behaviors in the home and combines individual, family and community level interventions to help immigrant men stop the abuse.…

  12. Veterans Health Administration: Management Attention Is Needed to Address Systemic, Long standing Human Capital Challenges

    Science.gov (United States)

    2016-12-01

    required by the Choice Act: the Independent Assessment of the Health Care Delivery Systems and Management Processes of the Department of Veterans...VETERANS HEALTH ADMINISTRATION Management Attention Is Needed to Address Systemic, Long-standing Human Capital...Government Accountability Office Highlights of GAO-17-30, a report to congressional requesters December 2016 VETERANS HEALTH ADMINISTRATION

  13. Managing Radioactive Waste. Problems and Challenges in a Globalizing World

    Energy Technology Data Exchange (ETDEWEB)

    2010-09-15

    Many countries are at a crossroads in terms of maintaining their energy supply. The existing resources of fossil fuels are dwindling, and global warming makes their use increasingly problematic. Nuclear power is now often regarded inevitable for future sustainability, energy security, and economic prosperity. There are, however, still unsolved problems regarding nuclear power. The fact that no country has established a final waste repository for spent nuclear fuel throws fundamental doubt on nuclear energy expansion. Also, the processes of globalization have transformed the nuclear industry towards increased privatization, concentration, and internationalization. This leads to uncertainties regarding the responsibility for nuclear waste management. In these circumstances is it of greatest importance that scholars from different disciplines, as well as policy makers and practitioners within the field, meet to share experiences. This conference had the general objective of producing knowledge about the challenges caused by global developmental trends, and what the management of nuclear waste implies for contemporary and future social development. Over 100 persons attended the conferences. Papers available at the conference site have been separately indexed. Several contributions were also made as PP-presentation, which are available at the site, among others the Keynote Speeches: Waiting for the Nuclear Renaissance: Exploring the Nexus of Expansion and Disposal in Europe (Jane Dawson); Applying the Risk Governance Framework: Institutional Requirements for Dealing with Nuclear Waste (Ortwin Renn); Learning to Listen: The Long Road to Legitimating Radioactive Waste Management Policies (Frans Berkhout); The Nuclear Waste Debate is Irrational but We Need Not Panic (Frank von Hippel). The conference was divided into the following sessions: Session A: Political characteristics matters; Session B: Radioactivity, geology, society. On a problem definition of HLW

  14. Accelerating global innovation to address antibacterial resistance: introducing CARB-X.

    Science.gov (United States)

    Outterson, Kevin; Rex, John H; Jinks, Tim; Jackson, Peter; Hallinan, John; Karp, Steve; Hung, Deborah T; Franceschi, Francois; Merkeley, Tyler; Houchens, Christopher; Dixon, Dennis M; Kurilla, Michael G; Aurigemma, Rosemarie; Larsen, Joseph

    2016-09-01

    A global response to the chronic shortfall in antibiotic innovation is urgently needed to combat antimicrobial resistance. Here, we introduce CARB-X, a new global public-private partnership that will invest more than US$350 million in the next 5 years to accelerate the progression of a diverse portfolio of innovative antibacterial products into clinical trials.

  15. Addressing Challenges in Web Accessibility for the Blind and Visually Impaired

    Science.gov (United States)

    Guercio, Angela; Stirbens, Kathleen A.; Williams, Joseph; Haiber, Charles

    2011-01-01

    Searching for relevant information on the web is an important aspect of distance learning. This activity is a challenge for visually impaired distance learners. While sighted people have the ability to filter information in a fast and non sequential way, blind persons rely on tools that process the information in a sequential way. Learning is…

  16. Addressing Army Aviation Collective Training Challenges with Simulators and Simulations Capabilities

    Science.gov (United States)

    2012-08-01

    Aptima, Inc. Technical Review by William Bickley, U.S. Army Research Institute Heather Priest-Walker, U.S. Army Research Institute...training challenges at home station and at Aviation Training Exercises. This report benefitted from the thoughtful comments of Drs. William Bickley and...environment, cockpit instrumentation, communications, weapons systems, gunnery environment, AH64 TADS , NVG (Night Vision Goggles) Simulation, EDMs

  17. A Model Driven Framework to Address Challenges in a Mobile Learning Environment

    Science.gov (United States)

    Khaddage, Ferial; Christensen, Rhonda; Lai, Wing; Knezek, Gerald; Norris, Cathie; Soloway, Elliot

    2015-01-01

    In this paper a review of the pedagogical, technological, policy and research challenges and concepts underlying mobile learning is presented, followed by a brief description of categories of implementations. A model Mobile learning framework and dynamic criteria for mobile learning implementations are proposed, along with a case study of one site…

  18. Narrative Research Addressing the Challenges of a Career in Professional Sports

    Science.gov (United States)

    Frankl, Daniel

    2013-01-01

    The purpose of this article is to highlight the challenges that accomplished young athletes face as they aspire to become professional athletes. The data used in this study was derived from selected lived and told sport experiences of undergraduate and graduate kinesiology majors who were former competitive athletes. Additional data was derived…

  19. The Benefits and Challenges of Becoming Cross-Culturally Competent Counseling Psychologists. Presidential Address

    Science.gov (United States)

    Heppner, P. Paul

    2006-01-01

    The central thesis of this article is that focusing on cross-cultural competence will enhance both the science and the practice of counseling psychology. Developing cross-cultural competence is a lifelong journey, replete with many joys and challenges, that will (a) increase the sophistication of our research, (b) expand the utility and…

  20. The Benefits and Challenges of Becoming Cross-Culturally Competent Counseling Psychologists. Presidential Address

    Science.gov (United States)

    Heppner, P. Paul

    2006-01-01

    The central thesis of this article is that focusing on cross-cultural competence will enhance both the science and the practice of counseling psychology. Developing cross-cultural competence is a lifelong journey, replete with many joys and challenges, that will (a) increase the sophistication of our research, (b) expand the utility and…

  1. A Model Driven Framework to Address Challenges in a Mobile Learning Environment

    Science.gov (United States)

    Khaddage, Ferial; Christensen, Rhonda; Lai, Wing; Knezek, Gerald; Norris, Cathie; Soloway, Elliot

    2015-01-01

    In this paper a review of the pedagogical, technological, policy and research challenges and concepts underlying mobile learning is presented, followed by a brief description of categories of implementations. A model Mobile learning framework and dynamic criteria for mobile learning implementations are proposed, along with a case study of one site…

  2. Global land cover mapping using Earth observation satellite data: Recent progresses and challenges

    Science.gov (United States)

    Ban, Yifang; Gong, Peng; Giri, Chandra

    2015-05-01

    Land cover is an important variable for many studies involving the Earth surface, such as climate, food security, hydrology, soil erosion, atmospheric quality, conservation biology, and plant functioning. Land cover not only changes with human caused land use changes, but also changes with nature. Therefore, the state of land cover is highly dynamic. In winter snow shields underneath various other land cover types in higher latitudes. Floods may persist for a long period in a year over low land areas in the tropical and subtropical regions. Forest maybe burnt or clear cut in a few days and changes to bare land. Within several months, the coverage of crops may vary from bare land to nearly 100% crops and then back to bare land following harvest. The highly dynamic nature of land cover creates a challenge in mapping and monitoring which remains to be adequately addressed. As economic globalization continues to intensify, there is an increasing trend of land cover/land use change, environmental pollution, land degradation, biodiversity loss at the global scale, timely and reliable information on global land cover and its changes is urgently needed to mitigate the negative impact of global environment change.

  3. Review: Automation and meat quality-global challenges.

    Science.gov (United States)

    Barbut, Shai

    2014-01-01

    The global meat industry has seen significant changes in the methods used to harvest and process fresh meat over the past century. Increased use of automation has led to significant increases in line speed for beef, pork, sheep, poultry and fish operations. For example, currently the fastest line observed has been broilers at 13,500/h. Such developments have required in-depth understanding of the pre and post rigor processes to prevent defects. Procedures such as maturation chilling and electrical stimulation are now common in red meat and poultry processing; allowing shorter time to deboning, while harvesting high quality meat. Robots designed to cut meat are also appearing on the market, and replacing traditional manual operations. This is a challenge, because high speed equipment is not necessarily sensitive to variations in size/quality issues, and requires development of unique sensors and control systems. Also, progress in breeding and genetics is contributing to greater product uniformity and quality; helping in operating automated equipment.

  4. City planning and population health: a global challenge.

    Science.gov (United States)

    Giles-Corti, Billie; Vernez-Moudon, Anne; Reis, Rodrigo; Turrell, Gavin; Dannenberg, Andrew L; Badland, Hannah; Foster, Sarah; Lowe, Melanie; Sallis, James F; Stevenson, Mark; Owen, Neville

    2016-12-10

    Significant global health challenges are being confronted in the 21st century, prompting calls to rethink approaches to disease prevention. A key part of the solution is city planning that reduces non-communicable diseases and road trauma while also managing rapid urbanisation. This Series of papers considers the health impacts of city planning through transport mode choices. In this, the first paper, we identify eight integrated regional and local interventions that, when combined, encourage walking, cycling, and public transport use, while reducing private motor vehicle use. These interventions are destination accessibility, equitable distribution of employment across cities, managing demand by reducing the availability and increasing the cost of parking, designing pedestrian-friendly and cycling-friendly movement networks, achieving optimum levels of residential density, reducing distance to public transport, and enhancing the desirability of active travel modes (eg, creating safe attractive neighbourhoods and safe, affordable, and convenient public transport). Together, these interventions will create healthier and more sustainable compact cities that reduce the environmental, social, and behavioural risk factors that affect lifestyle choices, levels of traffic, environmental pollution, noise, and crime. The health sector, including health ministers, must lead in advocating for integrated multisector city planning that prioritises health, sustainability, and liveability outcomes, particularly in rapidly changing low-income and middle-income countries. We recommend establishing a set of indicators to benchmark and monitor progress towards achievement of more compact cities that promote health and reduce health inequities.

  5. Using a complex system approach to address world challenges in Food and Agriculture

    CERN Document Server

    van Mil, H G J; Windhab, E J; Perrot, N; van der Linden, E

    2013-01-01

    World food supply is crucial to the well-being of every human on the planet in the basic sense that we need food to live. It also has a profound impact on the world economy, international trade and global political stability. Furthermore, consumption of certain types and amounts foods can affect health, and the choice of livestock and plants for food production can impact sustainable use of global resources. There are communities where insufficient food causes nutritional deficiencies, and at the same time other communities eating too much food leading to obesity and accompanying diseases. These aspects reflect the utmost importance of agricultural production and conversion of commodities to food products. Moreover, all factors contributing to the food supply are interdependent, and they are an integrative part of the continuously changing, adaptive and interdependent systems in the world around us. The properties of such interdependent systems usually cannot be inferred from the properties of its parts. In a...

  6. Addressing Challenges in the Acquisition of Secure Software Systems With Open Architectures

    Science.gov (United States)

    2012-04-30

    Director, Office of Acquisition Resources and Analysis ( ARA )  Deputy Assistant Secretary of the Navy, Acquisition & Procurement  Director of Open...Asuncion, 2010; Scacchi & Alspaugh, 2008) may therefore be extendable to also address OA systems with heterogeneous software security license rights and... heterogeneously licensed systems. In Proceedings of the 17th IEEE International Requirements Engineering Conference (pp. 24–33). Alspaugh, T. A., Asuncion, H

  7. The adequacy of the current social plan to address retrenchment challenges in South Africa

    Directory of Open Access Journals (Sweden)

    Thulane Ngele

    2008-11-01

    Full Text Available The purpose of the Social Plan Guidelines is to manage large-scale retrenchments and ameliorate their effects on employees. In this study a comprehensive literature review and two case studies were conducted to review the theoretical and practical application of the Social Plan. The research findings identified various challenges that inhibit the effective management of retrenchments. These challenges were analysed and interpreted and a new model to effectively manage retrenchments was developed. The new model is centred on a company’s business plan; the concept is a participative performance-driven governance approach between management and employees focusing on business results. The new model suggests that the employment relations management and corporate social investment of an organisation be utilised as vehicles to manage retrenchments effectively.

  8. Addressing healthcare-associated infections and antimicrobial resistance from an organizational perspective: progress and challenges.

    Science.gov (United States)

    Murray, Eleanor; Holmes, Alison

    2012-07-01

    This paper explores the progress and challenges associated with the application of organizational factors and approaches to infection prevention and control (IPC) and antibiotic stewardship (AS) in England, many of which have been considered and supported by the Advisory Committee on Antimicrobial Resistance and Healthcare-associated Infections (ARHAI). An organizational perspective is described and the wider macro context and socio-political forces that shape an organizational approach are considered. Factors that drive organizational change in IPC and AS are discussed. The tensions, constraints and dilemmas that can occur are identified and outstanding challenges are debated. Some recommendations for the future direction of IPC and AS organizationally focused strategies and research are proposed.

  9. Permitting Precariousness: Addressing Employment Standards Challenges for Temporary Foreign Workers in British Columbia

    OpenAIRE

    Pati, Angela Neelam

    2016-01-01

    Since 2002, there has been an increase in the number of low-skill and low-wage temporary foreign workers in Canada. This study examines the employment standards challenges that these workers may encounter while in the Temporary Foreign Worker Program. Employment standards legislation provides the minimum requirements for workplace procedures, conditions, and transactions, such as overtime pay and hours of work. Given that the regulation of labour and employment fall under provincial jurisdict...

  10. A DHS Skunkworks Project: Defining and Addressing Homeland Security Grand Challenges

    Science.gov (United States)

    2016-12-01

    million and one scotch and wine IOUs to Uncle Jay and Aunt Barb for their warm and endless hospitality . Finally, I would like to express my gratitude to...original inspiration for these challenges. To catalyze a new industry of space tourism , Diamandis launched the $10 million XPRIZE. Following high...that space tourism could be a reality beyond the pages of science fiction. It was through these lenses that Diamandis recognized the market failures of

  11. Elections: DOD Needs More Comprehensive Planning to Address Military and Overseas Absentee Voting Challenges

    Science.gov (United States)

    2016-04-01

    members of military personnel, overseas federal government employees , and overseas civilian voters—as well as challenges faced by FVAP within its own...according to officials. However, overseas citizens use foreign postal systems and DOD reported that civilians who use those systems expressed distrust ...mission, goals, and strategies. 6. Develop and use performance measures: DOD stated that FVAP and each of its employees are evaluated by yearly

  12. Strategies to increase demand for maternal health services in resource-limited settings: challenges to be addressed.

    LENUS (Irish Health Repository)

    Elmusharaf, Khalifa

    2015-09-01

    Universal health access will not be achieved unless women are cared for in their own communities and are empowered to take decisions about their own health in a supportive environment. This will only be achieved by community-based demand side interventions for maternal health access. In this review article, we highlight three common strategies to increase demand-side barriers to maternal healthcare access and identify the main challenges that still need to be addressed for these strategies to be effective.

  13. A historical review on the roles of science and politics in addressing global environmental issues

    Institute of Scientific and Technical Information of China (English)

    Peter USHER; Qian YE

    2009-01-01

    Based on a historical review of the so-called Ozone crisis in the late 1970s and global climate changes since the 1980s, this paper examines the role of sciences and policies in the international community in dealing with the global environmental issues. Lessons show that a multi-discipline, multi-organizational and multi-national UN agency which remains relevant, assisting rather than guiding the process of climate negotiations is important.

  14. The Global Challenge of Human Rights and Solidarity to Nordic Global Companies and Trade Unions

    Directory of Open Access Journals (Sweden)

    Bernt Schiller

    2014-03-01

    Full Text Available The idea that corporations, besides making profit, have a social responsibility to society is not new in history. Nor is it new that unions besides representing material interests stand for a universal ambition as defenders of the oppressed in the world. The article argues that corporations’ social responsibility and trade union solidarity, to the extent both are based on universal principles of human rights, ought to open for cooperation concerning Corporate Social Responsibility (CSR, where trade unions should be recognized as important stakeholders in corporations. This idea is new, even if examples exist, and it challenges traditional concepts of the role of management and unions in the company. However, trade unions have taken a critical attitude to CSR, the implementation of which they have mainly been excluded from. Instead, they have tried to get global agreements, Global Framework Agreements (GFAs, with the MNCs.1 In the article the development of the attitudes of the International Trade Union Confederation (ITUC and of the Nordic national centers is investigated. A long-term historical perspective, in addition to a general theory of collective action will be used to draft the hypothesis that, when unions as interest organizations, through the process of national integration, have achieved a strong position in the domestic labor market, they lack reasons to take transnational action and seek international trade union solidarity. This hypothesis is valid today for the well-established unions in the Nordic countries. But in questions concerning social responsibility and human rights, the article presents the possibility that GFAs might become a platform from which to extend the Nordic model of national partnership to the global level, while at the same time global competition will increasingly make it difficult for the unions to show international solidarity in interest questions of capital investments and outsourcing.

  15. Food security for Africa: an urgent global challenge

    Directory of Open Access Journals (Sweden)

    Sasson Albert

    2012-04-01

    Full Text Available Abstract In 2012, food insecurity is still a major global concern as 1 billion people are suffering from starvation, under-, and malnutrition, and the Food and Agriculture Organization of the United Nations (FAO has concluded that we are still far from reaching millennium development goal (MDG number 1: to halve extreme poverty and hunger by 2015. In sub-Saharan Africa, the number of people suffering from hunger is estimated at 239 million, and this figure could increase in the near future. There are many examples of food insecurity in sub-Saharan Africa, some of them having reached catastrophic dimensions, for example, in the Horn of Africa or southern Madagascar. Food insecurity is not just about insufficient food production, availability, and intake, it is also about the poor quality or nutritional value of the food. The detrimental situation of women and children is particularly serious, as well as the situation among female teenagers, who receive less food than their male counterparts in the same households. Soaring food prices and food riots are among the many symptoms of the prevailing food crisis and insecurity. Climate change and weather vagaries, present and forecast, are generally compounding food insecurity and drastically changing farming activities, as diagnosed by the Consultative Group on International Agricultural Research (CGIAR in June 2011. The key cause of food insecurity is inadequate food production. Since the global food crisis of 2007–2008, there has been an increasing awareness throughout the world that we must produce more and better food; and we should not be derailed from this goal, despite some relief brought by the good cereal harvests in 2011–2012. This is particularly true in sub-Saharan Africa, which needs and wants to make its own green revolution. The African challenge indeed is key to mitigating food insecurity in the world. Commitments were made by the heads of states and governments of the African Union

  16. A medical school's approach to meeting the challenges of interdisciplinary global health education for resident physicians.

    Science.gov (United States)

    Martha, Carlough; Sylvia, Becker-Dreps; Samuel, Hawes; Bethany, Hodge; Ian, Martin; Denniston, Clark

    2016-01-01

    Following a similar trend among United States (US) medical students, US resident physicians are increasingly interested in pursuing global health education. Largely, residency education has lagged behind in addressing this demand. Time and curriculum requirements make meeting this need challenging. The Office of International Activities (OIA) at University of North Carolina-Chapel Hill (UNC-CH) was founded to provide support to students and residents in the area global health. In order to more fully understand resident physicians' attitudes and educational needs, a survey of incoming residents was undertaken. The OIA administered a survey for incoming first-year residents of all specialties in July 2012. The survey was administered over one month using Qualtrics® and the response rate was 60%. Although 42% of residents had had an international experience during medical school, only 36% reported they felt prepared to address issues of international public health, including travel medicine and immigrant health. Significant barriers to involvement in global health opportunities in residency education were identified, including lack of time, finances and mentorship. As has been previously documented for global health education for medical students, this study's residents saw significant barriers to international electives during residency, including lack of elective time, finances and family responsibilities. In response to the survey results, an interdisciplinary educational initiative was developed at our school. This included obtaining buy-in from core residency leadership, establishing a pathway to arrange experiences, competitive scholarships for travel, and initiation of interdisciplinary educational opportunities. Results may serve as a useful model for other academic centers in developed countries.

  17. Synthesis and review: Tackling the nitrogen management challenge: from global to local scales

    Science.gov (United States)

    Reis, Stefan; Bekunda, Mateete; Howard, Clare M.; Karanja, Nancy; Winiwarter, Wilfried; Yan, Xiaoyuan; Bleeker, Albert; Sutton, Mark A.

    2016-12-01

    One of the ‘grand challenges’ of this age is the anthropogenic impact exerted on the nitrogen cycle. Issues of concern range from an excess of fixed nitrogen resulting in environmental pressures for some regions, while for other regions insufficient fixed nitrogen affects food security and may lead to health risks. To address these issues, nitrogen needs to be managed in an integrated fashion, at a variety of scales (from global to local). Such management has to be based on a thorough understanding of the sources of reactive nitrogen released into the environment, its deposition and effects. This requires a comprehensive assessment of the key drivers of changes in the nitrogen cycle both spatially, at the field, regional and global scale and over time. In this focus issue, we address the challenges of managing reactive nitrogen in the context of food production and its impacts on human and ecosystem health. In addition, we discuss the scope for and design of management approaches in regions with too much and too little nitrogen. This focus issue includes several contributions from authors who participated at the N2013 conference in Kampala in November 2013, where delegates compiled and agreed upon the ‘Kampala Statement-for-Action on Reactive Nitrogen in Africa and Globally’. These contributions further underline scientifically the claims of the ‘Kampala Statement’, that simultaneously reducing pollution and increasing nitrogen available in the food system, by improved nitrogen management offers win-wins for environment, health and food security in both developing and developed economies. The specific messages conveyed in the Kampala Statement focus on improving nitrogen management (I), including the reduction of nitrogen losses from agriculture, industry, transport and energy sectors, as well as improving waste treatment and informing individuals and institutions (II). Highlighting the need for innovation and increased awareness among stakeholders (III

  18. Benefits and Risks of Financial Globalization : Challenges for Developing Countries

    OpenAIRE

    Schmukler, Sergio L.

    2004-01-01

    This paper discusses the benefits and risks that financial globalization entails for developing countries. Financial globalization can lead to large benefits, particularly to the development of the financial system. But financial globalization can also come with crises and contagion. The net effect of financial globalization is likely positive in the long run, with risks being more prevalent right after countries liberalize. So far, only some countries, sectors, and firms have ...

  19. THE CHALLENGES OF GLOBAL COMPETITIVENESS: THE INSTITUTIONS AND INNOVATION DEVELOPMENT

    OpenAIRE

    Iryna TARANENKO

    2010-01-01

    The paper is devoted to the analysis of the causes of decreasing Ukraine’s global competitiveness position, and the influence of the factors: “Higher education and training”, “Innovation”, “Institutions” on the global competitiveness of Ukrainian economy. The possibilities of increasing the global competitive position of Ukraine by intensification of innovative activity, development of the set of measures on strengthening the innovative components of global competitiveness have been examined....

  20. An Overview of Interdisciplinary Research at Notre Dame Addressing "Grand Challenges" in the Midwest and Great Lakes Region

    Science.gov (United States)

    Hamlet, A. F.; Bolster, D.; Tank, J. L.; Hellmann, J.; Christopher, S. F.; Sharma, A.; Chiu, C. M.

    2014-12-01

    The Midwest and Great Lakes region face a number of "Grand Challenges" associated with climate, land use, agriculture, and water resources infrastructure. These include sustainability of agricultural systems and related impacts to food security and the regional economy; sustainability of Great Lakes water levels; changing storm statistics and impacts to stormwater management and flooding; water quality in rivers and downstream receiving water bodies related to non-point source pollution on agricultural lands and combined sewer overflows in urban areas; urban impacts related to aging infrastructure and climate change, and ecosystem management and restoration. In the context of water management, groundwater resources are poorly understood in comparison with surface water resources, and regional-scale simulation models are needed to address questions of sustainability both in terms of supply and water quality. Interdisciplinary research at the University of Notre Dame is attempting to address these research challenges via 1) integrated macro-scale groundwater and surface water modeling to address issues related to sustainable water supply, ecosystem restoration, and agricultural impacts; 2) development of high-resolution regional climate models dynamically coupled to the Great Lakes to address urban impacts, changing storm statistics and to quantify precipitation and evaporation over the Great Lakes; 3) and integrated macro-scale hydrology and water quality modeling to assess the large-scale performance of innovative land management BMPs on agricultural land (such as the two-stage ditch, cover crops, and dynamic drainage control) intended to improve water quality.

  1. Children and Young People in Russia: Global Challenges of Modernity

    Directory of Open Access Journals (Sweden)

    Aleksandra Anatol’evna Shabunova

    2015-12-01

    Full Text Available The present-day world’s development is becoming more and more uneven and new global challenges are emerging. Russia should respond to them by enhancing its economic competitiveness, preserving and increasing its population and human potential, first of all, that of children and young people. The paper points out that for the Russian Federation with its vast territory and substantial reserves of natural resources the most important geopolitical challenges consist in the preservation and increase of population and human potential. The authors prove that the formation of the population of Russia is under double “pressure” of high mortality and low fertility; therefore, natural movement (decline is not completed by mechanical movement. In addition, the article determines that the share of young people in the total population is decreasing. For the first time in the history of Russia the share of children has become lower than the proportion of the elderly. In 2013 in 56 Russian regions, the proportion of children and adolescents accounted for less than 20% of the population (in the early 2000s, there were 41 such regions, and in 1990 – three. In addition to the reduction in the number of the population, child health potential is also deteriorating: about 35% of children in Russia are born ill or become ill in the near future (the figure is 30% in the Vologda Oblast. The number of adolescents aged 15–17 who are accounted for severe mental disorders is continuously increasing. The greatest socio-economic damage to the society comes from suicides that are widely spread among young people (the younger generation (persons up to 24 years old accounts for one third of all the potential years of life lost from suicides. At the same time, young people consider health more valuable than does the population as a whole (4.5 points vs 4.4 points on a five-point scale. But young people underestimate the importance of self-preservation behavior. World

  2. Defense Infrastructure: DOD Needs to Take Actions to Address Challenges in Meeting Federal Renewable Energy Goals

    Science.gov (United States)

    2009-12-01

    renewable energy be generated by sources placed into service in 1999 or later; and (3) the 2007 Defense Authorization Act directed that at least 25 percent of electricity consumed by DoD come from renewable sources in fiscal year 2025. GAO was asked to examine the following: (1) DoD’s progress toward these three key goals for consuming renewable energy in fiscal years 2007 and 2008, (2) challenges to DoD meeting those goals, and (3) DoD’s plans to meet the goals. GAO reviewed relevant laws and DoD and Department of Energy (DOE) policy,

  3. Addressing the Challenges of Multi-touchpoint Experience Design for Mobile Services

    DEFF Research Database (Denmark)

    Qin, Xiangang; Law, Effie Lai-Chong; Clemmensen, Torkil

    The quality of user experience relies heavily on the consistence and integration of multiple touch points along the journey of purchasing and using mobile services. The challenges caused by fragmented and distributed touch points might be well tackled by providing context-awareness design (CAD......). By analyzing the context of using mobile music services we come up with a framework of CAD. CAD can sense the differences of contexts behind multiple touch points, understand the meaning underneath, predict upcoming possible actions, give advice to users and offer customized and adaptive services....

  4. Global Education Reform Movement: Challenge to Nordic Childhood

    Directory of Open Access Journals (Sweden)

    Charlotte Ringsmose

    2017-09-01

    Full Text Available The international comparison and competitive focus on (academic performance, together with the growing awareness that early years impact children’s learning and development in education as well as over a lifetime, has resulted in heightened political interest in the learning of the youngest children. Politicians take action to achieve what they assume to be most effective approach, resulting in more centralized control, and more structured learning approaches introduced to children at still younger ages (Brogaard-Clausen, 2015: Brehony, 2000: Moss, 2013. In the Nordic countries1 there is a general concern for early years and the challenges facing early childhood education and care in an era of increasing globalization, with focus on accountability and academic competition (Ringsmose, Kragh-Müller, 2017. In Denmark, the social pedagogical tradition has been part of the culture of early childhood education for decades. In the social pedagogical tradition, relationships, play, and children’s influence are considered of key importance, and as the child’s natural way to learn about, and make sense of the world. It is considered that children learn and explore through play and participation embedded in the culture. Recently, the ministry of education has discussed more focused learning plans, and has tried out a program with more structured learning approaches. The gradual changes, together with the possible political action, are changes seriously threatening the social pedagogical tradition with more school-like, and more structured ways for children to interact. The purpose of this article is to present the Danish example as an alternative to the schoolification of early years that we see in many countries.

  5. Eschatology of Modern Totalitarianism and the Challenges of Globalization

    Directory of Open Access Journals (Sweden)

    Antoniu Alexandru FLANDORFER

    2014-08-01

    Full Text Available Along his history, Man has always been mesmerized by the ideal of creating an earthly paradise out of his habitat, so he implemented the vector of progress by means of the particular Myth that was inherent to each epoch. Man’s fascination with his exponential evolution in the world appeared with the industrial revolution that was gradually enhanced by the intrusion of politics. A mixture of political and socio-economic aspects was created with the sole purpose of consolidating such historical tendencies that led to the birth of the totalitarian regimes of the 20th c., taking the shapes of secular religions, (R. Aron, political / intra-mundane religions (E. Voegelin, religions of earthly redemption (E. Morin, ideologies of redemption (J. Freund. Nowadays, after the failure of politics, the semantic “pool” of collective imagination has received the addition of a new spasm of humankind that was generated by the following issues: the evolution of science up to a teleological praxis, the maximal efficiency of production leading to an inherent over-consumption, and, finally, the replacement of Christian morals by the ethical commandments of the society. Our research constitutes a phenomenological analysis of totalitarianism and the dystopian challenges of Globalization. We notice that both the Nazi or communist counter-utopias, and the present-day dystopia are the result of the secularization of religion; while the human being, stuck in a secular millenarianism, has sketched new coordinates in a godless environment. The solution to avoid humankind’s own moral suicide is to be found not in the social hypostases of individual, but in the return to mysticism. It is therefore necessary to return to the archetype rather than to a prototype that is permanently cloned in the process of uniformization of the society as a result of standardization and in the atomization of the individual through digital socialization.

  6. On the road to a stronger public health workforce: visual tools to address complex challenges.

    Science.gov (United States)

    Drehobl, Patricia; Stover, Beth H; Koo, Denise

    2014-11-01

    The public health workforce is vital to protecting the health and safety of the public, yet for years, state and local governmental public health agencies have reported substantial workforce losses and other challenges to the workforce that threaten the public's health. These challenges are complex, often involve multiple influencing or related causal factors, and demand comprehensive solutions. However, proposed solutions often focus on selected factors and might be fragmented rather than comprehensive. This paper describes approaches to characterizing the situation more comprehensively and includes two visual tools: (1) a fishbone, or Ishikawa, diagram that depicts multiple factors affecting the public health workforce; and (2) a roadmap that displays key elements-goals and strategies-to strengthen the public health workforce, thus moving from the problems depicted in the fishbone toward solutions. The visual tools aid thinking about ways to strengthen the public health workforce through collective solutions and to help leverage resources and build on each other's work. The strategic roadmap is intended to serve as a dynamic tool for partnership, prioritization, and gap assessment. These tools reflect and support CDC's commitment to working with partners on the highest priorities for strengthening the workforce to improve the public's health. Published by Elsevier Inc.

  7. Relative and absolute addressability of global disease burden in maternal and perinatal health by investment in R&D.

    Science.gov (United States)

    Fisk, Nicholas M; McKee, Martin; Atun, Rifat

    2011-06-01

    Maternal and perinatal disease accounts for nearly 10% of the global burden of disease, with only modest progress towards achievement of the Millennium Development Goals. Despite a favourable new global health landscape in research and development (R&D) to produce new drugs for neglected diseases, R&D investment in maternal/perinatal health remains small and non-strategic. Investment in obstetric R&D by industry or the not-for-profit sector has lagged behind other specialties, with the number of registered pipeline drugs only 1-5% that for other major disease areas. Using a Delphi exercise with maternal/perinatal experts in global and translational research, we estimate that equitable pharmaceutical R&D and public sector research funding over the next 10-20 years could avert 1.1% and 1.9% of the global disease burden, respectively. In contrast, optimal uptake of existing research would prevent 3.0%, justifying the current focus on health service provision. Although R&D predominantly occurs in high-income countries, more than 98% of the estimated reduction in disease burden in this field would be in developing countries. We conclude that better pharmaceutical and public sector R&D would prevent around 1/3 and 2/3, respectively, of the disease burden addressable by optimal uptake of existing research. Strengthening R&D may be an important complementary strategy to health service provision to address global maternal and perinatal disease burden. © 2011 Blackwell Publishing Ltd.

  8. Building a Global Earth Observation System of Systems (GEOSS) and Its Interoperability Challenges

    Science.gov (United States)

    Ryan, B. J.

    2015-12-01

    Launched in 2005 by industrialized nations, the Group on Earth Observations (GEO) began building the Global Earth Observation System of Systems (GEOSS). Consisting of both a policy framework, and an information infrastructure, GEOSS, was intended to link and/or integrate the multitude of Earth observation systems, primarily operated by its Member Countries and Participating Organizations, so that users could more readily benefit from global information assets for a number of society's key environmental issues. It was recognized that having ready access to observations from multiple systems was a prerequisite for both environmental decision-making, as well as economic development. From the very start, it was also recognized that the shear complexity of the Earth's system cannot be captured by any single observation system, and that a federated, interoperable approach was necessary. While this international effort has met with much success, primarily in advancing broad, open data policies and practices, challenges remain. In 2014 (Geneva, Switzerland) and 2015 (Mexico City, Mexico), Ministers from GEO's Member Countries, including the European Commission, came together to assess progress made during the first decade (2005 to 2015), and approve implementation strategies and mechanisms for the second decade (2016 to 2025), respectively. The approved implementation strategies and mechanisms are intended to advance GEOSS development thereby facilitating the increased uptake of Earth observations for informed decision-making. Clearly there are interoperability challenges that are technological in nature, and several will be discussed in this presentation. There are, however, interoperability challenges that can be better characterized as economic, governmental and/or political in nature, and these will be discussed as well. With the emergence of the Sustainable Development Goals (SDGs), the World Conference on Disaster Risk Reduction (WCDRR), and the United Nations

  9. GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma 'epidemic'

    DEFF Research Database (Denmark)

    Bousquet, J; Burney, P G; Zuberbier, T;

    2009-01-01

    Allergic diseases represent a major health problem in Europe. They are increasing in prevalence, severity and costs. The Global Allergy and Asthma European Network (GA(2)LEN), a Sixth EU Framework Program for Research and Technological Development (FP6) Network of Excellence, was created in 2005...... as a vehicle to ensure excellence in research bringing together research and clinical institutions to combat fragmentation in the European research area and to tackle allergy in its globality. The Global Allergy and Asthma European Network has benefited greatly from the voluntary efforts of researchers who...... are strongly committed to this model of pan-European collaboration. The network was organized in order to increase networking for scientific projects in allergy and asthma around Europe and to make GA(2)LEN the world leader in the field. Besides these activities, research has also been carried out...

  10. Strategies for Integrated Analysis of Genetic, Epigenetic, and Gene Expression Variation in Cancer: Addressing the Challenges

    DEFF Research Database (Denmark)

    Thingholm, Louise Bruun; Andersen, Lars; Makalic, Enes

    2016-01-01

    The development and progression of cancer, a collection of diseases with complex genetic architectures, is facilitated by the interplay of multiple etiological factors. This complexity challenges the traditional single-platform study design and calls for an integrated approach to data analysis....... However, integration of heterogeneous measurements of biological variation is a non-trivial exercise due to the diversity of the human genome and the variety of output data formats and genome coverage obtained from the commonly used molecular platforms. This review article will provide an introduction...... to integration strategies used for analyzing genetic risk factors for cancer. We critically examine the ability of these strategies to handle the complexity of the human genome and also accommodate information about the biological and functional interactions between the elements that have been measured...

  11. Addressing challenges in single species assessments via a simple state-space assessment model

    DEFF Research Database (Denmark)

    Nielsen, Anders

    Single-species and age-structured fish stock assessments still remains the main tool for managing fish stocks. A simple state-space assessment model is presented as an alternative to (semi) deterministic procedures and the full parametric statistical catch at age models. It offers a solution...... of state-space assessment models is that they tend to be more conservative (react slower to changes) than the alternatives. A solution to this criticism is offered by introducing a mixture distribution for the transitions steps. The model presented is used for several commercially important stocks...... to some of the key challenges of these models. Compared to the deterministic procedures it solves a list of problems originating from falsely assuming that age classified catches are known without errors and allows quantification of uncertainties of estimated quantities of interest. Compared to full...

  12. Polar Engineering and Research to Address Operational Challenges in Austere Environments

    Science.gov (United States)

    Mercer, J. L.; Richter-Menge, J.; Weale, J. C.; Lever, J. H.; Knuth, M. A.; Shoop, S. A.; Haehnel, R.; Arcone, S. A.; Bjella, K.; Finnegan, D. C.; Courville, Z.; Tracy, B. T.

    2009-12-01

    Logistics constraints and operational challenges in the austere environs of the polar regions present unique technological and engineering problems. Working closely with universities, government agencies and industry, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Lab (CRREL) routinely conducts scientific research and engineering in the Arctic, sub-Arctic and Antarctic covering a wide range of topics and applications. Current areas of focus include: improved mobility techniques for overland traverses; robotic vehicles for traversing, sampling and data collection; snow road and transportation characterization; integrated operational systems including airfield consolidation proof-of-concept studies; infrastructure technology such as firn air cooling, building design, snow foundations and sewage handling; remote/renewable autonomous power solutions for data collection; subsurface radar for crevasse detection and cryosphere characterization; ground-based lidar topographic scanning and near-real-time climate/environmental monitoring linked to AIS infrastructure. While these research and engineering efforts provide solutions and improved technology for specific problems, the impacts are many and wide-reaching and the results are often applicable to other challenging environments. Here, an overview of current research foci and projects is presented along with in-the-field applications, effects and future implications. The results and solutions of these efforts typically lead to technological improvements in operations and logistics which are cost-beneficial, thus freeing up funding dollars for fundamental scientific research. The links between basic research and applied solutions delivering far-reaching impacts (both large- and small-scale) on society, the environment, industry and scientific research are also demonstrated.

  13. Are we ready to accept the challenge? Addressing the shortcomings of contemporary qualitative health research.

    Science.gov (United States)

    Lau, Sofie Rosenlund; Traulsen, Janine M

    Qualitative approaches represent an important contributor to health care research. However, several researchers argue that contemporary qualitative research does not live up to its full potential. By presenting a snapshot of contemporary qualitative research in the field of social and administrative pharmacy, this study challenges contributors to the field by asking: Are we ready to accept the challenge and take qualitative research one step further? The purpose of this study was to initiate a constructive dialogue on the need for increased transparency in qualitative data analysis, including explicitly reflecting upon theoretical perspectives affecting the research process. Content analysis was used to evaluate levels of theoretical visibility and analysis transparency in selected qualitative research articles published in Research in Social and Administrative Pharmacy between January 2014 and January 2015. In 14 out of 21 assessed papers, the use of theory was found to be Seemingly Absent (lowest level of theory use), and the data analyses did not include any interpretive endeavors. Only two papers consistently applied theory throughout the entire study and clearly took the data analyses from a descriptive to an interpretive level. It was found that the aim of the majority of assessed papers was to change or modify a given practice, which however, resulted in a lack of both theoretical underpinnings and analysis transparency. This study takes the standpoint that theory and high-quality analysis go hand-in-hand. Based on the content analysis, articles that were deemed to be high in quality were explicit about the theoretical framework of their study and transparent in how they analyzed their data. It was found that theory contributed to the transparency of how the data were analyzed and interpreted. Two ways of improving contemporary qualitative research in the field of social and administrative pharmacy are discussed: engaging with social theory and establishing

  14. Implementing Peer Learning in Clinical Education: A Framework to Address Challenges In the "Real World".

    Science.gov (United States)

    Tai, Joanna Hong Meng; Canny, Benedict J; Haines, Terry P; Molloy, Elizabeth K

    2017-01-01

    Phenomenon: Peer learning has many benefits and can assist students in gaining the educational skills required in future years when they become teachers themselves. Peer learning may be particularly useful in clinical learning environments, where students report feeling marginalized, overwhelmed, and unsupported. Educational interventions often fail in the workplace environment, as they are often conceived in the "ideal" rather than the complex, messy real world. This work sought to explore barriers and facilitators to implementing peer learning activities in a clinical curriculum. Previous peer learning research results and a matrix of empirically derived peer learning activities were presented to local clinical education experts to generate discussion around the realities of implementing such activities. Potential barriers and limitations of and strategies for implementing peer learning in clinical education were the focus of the individual interviews. Thematic analysis of the data identified three key considerations for real-world implementation of peer learning: culture, epistemic authority, and the primacy of patient-centered care. Strategies for peer learning implementation were also developed from themes within the data, focusing on developing a culture of safety in which peer learning could be undertaken, engaging both educators and students, and establishing expectations for the use of peer learning. Insights: This study identified considerations and strategies for the implementation of peer learning activities, which took into account both educator and student roles. Reported challenges were reflective of those identified within the literature. The resultant framework may aid others in anticipating implementation challenges. Further work is required to test the framework's application in other contexts and its effect on learner outcomes.

  15. Addressing global challenges side by side-Interview with MPS President Prof. Peter Gruss

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ Prof. Peter Gruss, president of the Max Planck Society (MPS) and a winner of China's National Award for International S&T Cooperation in 2007, has long been committed to promoting the scientific cooperation between China and Germany. As early as in the 1980s, he went to Shanghai to teach advanced experimental techniques at the Guest Laboratory cosponsored by CAS and MPS. Since 2002 when he assumed the office of MPS president,

  16. Addressing AACSB Global and Technology Requirements: Exploratory Assessment of a Marketing Management Assignment

    Science.gov (United States)

    Greene, Scott; Bao, Yongchuan

    2009-01-01

    The Association to Advance Collegiate Schools of Business (AACSB) standards mandate knowledge of global and technology issues. Businesses desire employees with ability to analyze international markets and to be adept with technology. Taxpayers supporting public universities and organizations hiring business school graduates expect accountability…

  17. Partnerships as panacea for addressing global problems? On rationale, context, actors, impact and limitations

    NARCIS (Netherlands)

    Kolk, A.; Seitanidi, M.M; Crane, A.

    2014-01-01

    This chapter examines partnerships and their peculiarities, based on recent research from various disciplines, in the context of the large problems faced by (global) society. These problems are very complex, often cross national boundaries, and cannot easily be 'solved' by one single actor. Previous

  18. Addressing AACSB Global and Technology Requirements: Exploratory Assessment of a Marketing Management Assignment

    Science.gov (United States)

    Greene, Scott; Bao, Yongchuan

    2009-01-01

    The Association to Advance Collegiate Schools of Business (AACSB) standards mandate knowledge of global and technology issues. Businesses desire employees with ability to analyze international markets and to be adept with technology. Taxpayers supporting public universities and organizations hiring business school graduates expect accountability…

  19. EFA and the global agenda for education and development: Addressing critical questions and omissions

    NARCIS (Netherlands)

    Verger, A.; Novelli, M.

    2008-01-01

    This article raises some critical questions regarding the current global compact on education for development, represented by Education for All (EFA), and analyzes how its form and content are embedded in a neoliberal model of economic development. It also argues that this neoliberal embedding repre

  20. “Culture Education” and the Challenge of Globalization in Modern Nigeria

    Directory of Open Access Journals (Sweden)

    Ademola Omobewaji Dasylva

    2006-10-01

    Full Text Available This paper has to do with the challenges of globalization in modern Nigeria and the process of “culture education,” a terminology used to emphasize the peculiar means and methods of instruction by which a society imparts its body of values and mores in the pursuance and attainment of the society’s collective vision, aspirations, and goals. Within this framework, this paper examines the legacies of imperialism and colonization within the Nigerian educational system––particularly in reference to the teaching of folklore and oral tradition––including the destruction of indigenous knowledge systems and the continuing lack of adequate resources in African universities. The paper concludes by offering suggestions for a more fully synthesized indigenous and formal Nigerian educational system as a method of addressing postcolonial rupture.

  1. Addressing the ethical, policy, and social challenges of preclinical Alzheimer disease.

    Science.gov (United States)

    Karlawish, Jason

    2011-10-11

    Research suggests that Alzheimer disease (AD) pathophysiology begins prior to the clinical expression of the disease and that biomarker measures may provide direct evidence of this process. As a result, it may be possible to uncouple the diagnosis of AD from the clinical expression of the disease. The shifting boundaries between normal brain aging and disease present 3 challenges: 1) establishing guidelines for researchers and clinicians to safely and effectively communicate the diagnosis of preclinical AD, 2) setting up a process that effectively translates this diagnosis into practice and policy, and 3) adapting laws, regulations, and professional practices to the diagnosis of preclinical AD. The field of genetic testing for AD suggests how to balance a patient's desire to know his or her risk of developing dementia with a clinician's desire to mitigate the potential harms of that information. The development of diagnostic and treatment guidelines for other diseases of aging, such as cardiovascular disease, suggests the need for a National Alzheimer's Education Program to develop policies and procedures to translate preclinical AD into both clinical practice and policy. Revisions are needed to laws, regulations, and professional practices governing driving, financial management and planning, and privacy and confidentiality.

  2. Addressing fundamental architectural challenges of an activity-based intelligence and advanced analytics (ABIAA) system

    Science.gov (United States)

    Yager, Kevin; Albert, Thomas; Brower, Bernard V.; Pellechia, Matthew F.

    2015-06-01

    The domain of Geospatial Intelligence Analysis is rapidly shifting toward a new paradigm of Activity Based Intelligence (ABI) and information-based Tipping and Cueing. General requirements for an advanced ABIAA system present significant challenges in architectural design, computing resources, data volumes, workflow efficiency, data mining and analysis algorithms, and database structures. These sophisticated ABI software systems must include advanced algorithms that automatically flag activities of interest in less time and within larger data volumes than can be processed by human analysts. In doing this, they must also maintain the geospatial accuracy necessary for cross-correlation of multi-intelligence data sources. Historically, serial architectural workflows have been employed in ABIAA system design for tasking, collection, processing, exploitation, and dissemination. These simpler architectures may produce implementations that solve short term requirements; however, they have serious limitations that preclude them from being used effectively in an automated ABIAA system with multiple data sources. This paper discusses modern ABIAA architectural considerations providing an overview of an advanced ABIAA system and comparisons to legacy systems. It concludes with a recommended strategy and incremental approach to the research, development, and construction of a fully automated ABIAA system.

  3. Strategies for integrated analysis of genetic, epigenetic and gene expression variation in cancer: addressing the challenges

    Directory of Open Access Journals (Sweden)

    Louise Bruun Thingholm

    2016-02-01

    Full Text Available The development and progression of cancer, a collection of diseases with complex genetic architectures, is facilitated by the interplay of multiple etiological factors. This complexity challenges the traditional single-platform study design and calls for an integrated approach to data analysis. However, integration of heterogeneous measurements of biological variation is a non-trivial exercise due to the diversity of the human genome and the variety of output data formats and genome coverage obtained from the commonly used molecular platforms. This review article will provide an introduction to integration strategies used for analyzing genetic risk factors for cancer. We critically examine the ability of these strategies to handle the complexity of the human genome and also accommodate information about the biological and functional interactions between the elements that have been measured – making the assessment of disease risk against a composite genomic factor possible. The focus of this review is to provide an overview and introduction to the main strategies and to discuss where there is a need for further development.

  4. Vision for cross-layer optimization to address the dual challenges of energy and reliability

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Heather M [Los Alamos National Laboratory; Dehon, Andre [U. PENN; Carter, Nicholas P [INTEL

    2009-01-01

    We are rapidly approaching an inflection point where the conventional target of producing perfect, identical transistors that operate without upset can no longer be maintained while continuing to reduce the energy per operation. With power requirements already limiting chip performance, continuing to demand perfect, upset-free transistors would mean the end of scaling benefits. The big challenges in device variability and reliability are driven by uncommon tails in distributions, infrequent upsets, one-size-fits-all technology requirements, and a lack of information about the context of each operation. Solutions co-designed across traditional layer boundaries in our system stack can change the game, allowing architecture and software (a) to compensate for uncommon variation, environments, and events, (b) to pass down invariants and requirements for the computation, and (c) to monitor the health of collections of deVices. Cross-layer codesign provides a path to continue extracting benefits from further scaled technologies despite the fact that they may be less predictable and more variable. While some limited multi-layer mitigation strategies do exist, to move forward redefining traditional layer abstractions and developing a framework that facilitates cross-layer collaboration is necessary.

  5. 2010 Presidential Address: Learning Religion and Religiously Learning amid Global Cultural Flows

    Science.gov (United States)

    Hess, Mary E.

    2011-01-01

    Emerging social media that build on digital technologies are reshaping how we interact with each other. Religious education and identity formation within these new cultural flows demands recognition of the shifts in authority, authenticity, and agency that are taking place, as well as the challenges posed by "context collapse." Digital…

  6. Addressing the challenges of cleft lip and palate research in India

    Directory of Open Access Journals (Sweden)

    Mossey Peter

    2009-10-01

    Full Text Available The Indian sub-continent remains one of the most populous areas of the world with an estimated population of 1.1 billion in India alone. This yields an estimated 24.5 million births per year and the birth prevalence of clefts is somewhere between 27,000 and 33,000 clefts per year. Inequalities exist, both in access to and quality of cleft care with distinct differences in urban versus rural access and over the years the accumulation of unrepaired clefts of the lip and palate make this a significant health care problem in India. In recent years the situation has been significantly improved through the intervention of Non Governmental Organisations such as SmileTrain and Transforming Faces Worldwide participating in primary surgical repair programmes. The cause of clefts is multi factorial with both genetic and environmental input and intensive research efforts have yielded significant advances in recent years facilitated by molecular technologies in the genetic field. India has tremendous potential to contribute by virtue of improving research expertise and a population that has genetic, cultural and socio-economic diversity. In 2008, the World Health Organisation (WHO has recognised that non-communicable diseases, including birth defects cause significant infant mortality and childhood morbidity and have included cleft lip and palate in their Global Burden of Disease (GBD initiative. This will fuel the interest of India in birth defects registration and international efforts aimed at improving quality of care and ultimately prevention of non-syndromic clefts of the lip and palate.

  7. Technical Reference Suite Addressing Challenges of Providing Assurance for Fault Management Architectural Design

    Science.gov (United States)

    Fitz, Rhonda; Whitman, Gerek

    2016-01-01

    Research into complexities of software systems Fault Management (FM) and how architectural design decisions affect safety, preservation of assets, and maintenance of desired system functionality has coalesced into a technical reference (TR) suite that advances the provision of safety and mission assurance. The NASA Independent Verification and Validation (IV&V) Program, with Software Assurance Research Program support, extracted FM architectures across the IV&V portfolio to evaluate robustness, assess visibility for validation and test, and define software assurance methods applied to the architectures and designs. This investigation spanned IV&V projects with seven different primary developers, a wide range of sizes and complexities, and encompassed Deep Space Robotic, Human Spaceflight, and Earth Orbiter mission FM architectures. The initiative continues with an expansion of the TR suite to include Launch Vehicles, adding the benefit of investigating differences intrinsic to model-based FM architectures and insight into complexities of FM within an Agile software development environment, in order to improve awareness of how nontraditional processes affect FM architectural design and system health management. The identification of particular FM architectures, visibility, and associated IV&V techniques provides a TR suite that enables greater assurance that critical software systems will adequately protect against faults and respond to adverse conditions. Additionally, the role FM has with regard to strengthened security requirements, with potential to advance overall asset protection of flight software systems, is being addressed with the development of an adverse conditions database encompassing flight software vulnerabilities. Capitalizing on the established framework, this TR suite provides assurance capability for a variety of FM architectures and varied development approaches. Research results are being disseminated across NASA, other agencies, and the

  8. New Challenges for Urban History: Culture, Networks, Globalization

    Directory of Open Access Journals (Sweden)

    Hietala, Marjatta

    2012-12-01

    Full Text Available Urban history is a very lively and dynamic research field, showing strict parallelism with the fast increasing of the urban population. Today, competitiveness is one of the key aims for cities in the globalized world. Factors such as accessibility and infrastructure, industry, human capital, innovation, and investment, green spaces, affordable housing, business support and quality of education are necessaries. However, the OECD recognizes three dilemmas in this strategic vision, concerning the spill over of metro-regions, the public strategic vision, and the relationship between economic dynamism and the liveable city. Today urban historians are facing some general challenges: comparative aspects are needed; also interdisciplinarity to develop cooperation between disciplines; and for maintaining the professional status of academic urban history. The expanding networks between towns and cities, and the meeting places as conferences and exhibitions are considered, as they are the multitudinous challenges and threats, especially for those cities suffering continuously of major natural and man-made disasters. Moreover, new amalgams of hazard are being created in metropolitan areas with overlapping natural, technological, biological and social risks, exposing more people and places, needing safety and security.

    La historia urbana es un campo de investigación muy vivo y dinámico, mostrando un paralelismo estricto con el rápido incremento de la población urbana. La competencia es hoy uno de los objetivos claves para las ciudades en el mundo globalizado. Factores tales como la accesibilidad y las infraestructuras, la industria, el capital humano, la innovación y la inversión, los espacios verdes, la vivienda accesible, el apoyo a los negocios y la calidad de la educación son necesarios. Sin embargo, la OCDE reconoce tres dilemas en esa visión estratégica, el desarrollo de las metrópolis, la visión estratégica pública y la relaci

  9. Malaria: Global progress 2000 - 2015 and future challenges.

    Science.gov (United States)

    Cibulskis, Richard E; Alonso, Pedro; Aponte, John; Aregawi, Maru; Barrette, Amy; Bergeron, Laurent; Fergus, Cristin A; Knox, Tessa; Lynch, Michael; Patouillard, Edith; Schwarte, Silvia; Stewart, Saira; Williams, Ryan

    2016-06-09

    2015 was the target year for malaria goals set by the World Health Assembly and other international institutions to reduce malaria incidence and mortality. A review of progress indicates that malaria programme financing and coverage have been transformed since the beginning of the millennium, and have contributed to substantial reductions in the burden of disease. Investments in malaria programmes increased by more than 2.5 times between 2005 and 2014 from US$ 960 million to US$ 2.5 billion, allowing an expansion in malaria prevention, diagnostic testing and treatment programmes. In 2015 more than half of the population of sub-Saharan Africa slept under insecticide-treated mosquito nets, compared to just 2 % in 2000. Increased availability of rapid diagnostic tests and antimalarial medicines has allowed many more people to access timely and appropriate treatment. Malaria incidence rates have decreased by 37 % globally and mortality rates by 60 % since 2000. It is estimated that 70 % of the reductions in numbers of cases in sub-Saharan Africa can be attributed to malaria interventions. Reductions in malaria incidence and mortality rates have been made in every WHO region and almost every country. However, decreases in malaria case incidence and mortality rates were slowest in countries that had the largest numbers of malaria cases and deaths in 2000; reductions in incidence need to be greatly accelerated in these countries to achieve future malaria targets. Progress is made challenging because malaria is concentrated in countries and areas with the least resourced health systems and the least ability to pay for system improvements. Malaria interventions are nevertheless highly cost-effective and have not only led to significant reductions in the incidence of the disease but are estimated to have saved about US$ 900 million in malaria case management costs to public providers in sub-Saharan Africa between 2000 and 2014. Investments in malaria programmes can not

  10. Antimicrobial resistance: addressing the global threat through greater awareness and transformative action.

    Science.gov (United States)

    Keown, Oliver P; Warburton, Will; Davies, Sally C; Darzi, Ara

    2014-09-01

    Antimicrobial therapies have played an unquestionably important role in advancing modern medical and surgical care, treating animals, reducing the global burden of communicable disease, and prolonging human life expectancy. These transformational benefits are threatened because of the rapidly advancing phenomenon of antimicrobial resistance. As a result of complex factors across many sectors and international actors, the global impact of antimicrobial resistance is an escalating economic and health crisis. This article draws on the collective expertise and summit report of the Antimicrobial Resistance Working Group from the 2013 World Innovation Summit for Health, in Doha, Qatar. It defines a framework of principles and tasks for key policy makers to raise international awareness of antimicrobial resistance and lead transformative action through policy-driven improvements in sanitation, antimicrobial conservation, agricultural practices, and research and development.

  11. The ebola crisis : challenges for global health law

    NARCIS (Netherlands)

    Toebes, Brigit

    2015-01-01

    he recent Ebola crisis has caused approximately 20.000 deaths so far. Compared to other global health crises, including the deaths caused by armed conflicts and chronic diseases, this is still a small amount. Yet, from a global and domestic health law and governance perspective, this crisis raises a

  12. [The modern international public health and globalization challenges].

    Science.gov (United States)

    2012-01-01

    The article deals with the issues of impact of globalization on population health and public health. The positive and negative aspects of this process are analyzed. The role of international organizations (UN, WHO, UNESCO, ILO, UNISEF) is demonstrated in the area of management of globalization impact on public health of different countries, Russia included.

  13. Faith & Globalization:the Challenge for Higher Education

    Science.gov (United States)

    Blair, Tony; Bardsley, Craig

    2013-01-01

    Globalization continues to transform how universities work: the students and subjects they teach, and the way they conduct and disseminate research. With tight budgets everywhere in the wake of the global economic downturn, universities are under increasing pressure to demonstrate value for money to the wider public from their research and…

  14. Faith & Globalization:the Challenge for Higher Education

    Science.gov (United States)

    Blair, Tony; Bardsley, Craig

    2013-01-01

    Globalization continues to transform how universities work: the students and subjects they teach, and the way they conduct and disseminate research. With tight budgets everywhere in the wake of the global economic downturn, universities are under increasing pressure to demonstrate value for money to the wider public from their research and…

  15. The ebola crisis : challenges for global health law

    NARCIS (Netherlands)

    Toebes, Brigit

    2015-01-01

    he recent Ebola crisis has caused approximately 20.000 deaths so far. Compared to other global health crises, including the deaths caused by armed conflicts and chronic diseases, this is still a small amount. Yet, from a global and domestic health law and governance perspective, this crisis raises a

  16. Road traffic injuries and data systems in Egypt: addressing the challenges.

    Science.gov (United States)

    Puvanachandra, P; Hoe, C; El-Sayed, H F; Saad, R; Al-Gasseer, N; Bakr, M; Hyder, A A

    2012-01-01

    Road traffic injuries (RTIs) are a major cause of global mortality and morbidity, killing approximately 1.3 million people and injuring 20 to 50 million each year. The significance of this public health threat is most pronounced in low- and middle-income countries where 90 percent of the world's road traffic-related fatalities take place. Current estimates for Egypt show a road traffic fatality rate of 42 deaths per 100,000 population-one of the highest in the Eastern Mediterranean Region. RTIs are also responsible for 1.8 percent of all deaths and 2.4 percent of all disability-adjusted life years (DALYs) lost in the country. Despite this, studies surrounding this topic are scarce, and reliable data are limited. The overall goal of this article is to define the health impact of RTIs in Egypt and to identify the strengths and weaknesses of each data source for the purpose of improving the current RTI data systems. A 2-pronged approach was undertaken to assess the burden of RTIs in Egypt. First, a thorough literature review was performed using PubMed, Embase, ISIS Web of Knowledge, and Scopus databases. Articles pertaining to Egypt and road traffic injuries were selected for screening. With assistance from Egyptian colleagues, a comprehensive exploration of data sources pertaining to RTIs in Egypt was undertaken and secondary data from these sources were procured for analysis. The literature review yielded a total of 20 studies, of which 6 were multi-country and 5 were hospital-based studies. None examined risk factors such as speeding, alcohol, or seat belt use. Secondary data sources were acquired from national hospital-based injury surveillance; a community-based health survey; pre-hospital injury surveillance; the Ministry of Transport; the General Authority for Roads, Bridges and Land Transport; death certificates; and the central agency for public motorization and statistics. Risk factor data are also limited from these sources. The results of this article

  17. Constructing pragmatic socioeconomic status assessment tools to address health equality challenges

    Directory of Open Access Journals (Sweden)

    Parvin Tajik

    2014-01-01

    Full Text Available Background: A key challenge for equality evaluation and monitoring, mainly in developing countries, is assessing socioeconomic status (SES of individuals. This difficulty along with low technical competency, have resulted in many health information collected in these countries which are devoid of suitable SES indices. However, simplifying data collection requirements for estimating economic parameters seems to guarantee their wide adoption by survey and health information system (HIS designers, resulting in immediate production of equity-oriented policy-relevant information. The goal of this study is obtaining adequate number of variables, which their combination can provide a valid assessment of SES in Iranian population. Methods: The data source was Living Standards Measurement Study of Iran (2006. Data of 27,000 households on the ownership of 33 household assets was used for this analysis. Households of this study were divided into 5 groups in terms of SES status using principle component analysis. Then selection was made among the 33 variables so that a combination with minimum necessary number for obtaining SES status is reached. Agreement of the new combination (including minimum number of variables with full variable combination (including all 33 variables was assessed using weighted kappa. Results: A minimum set of six variables including having kitchen, bathroom, vacuum cleaner, washing machine, freezer and personal computer could successfully discriminate SES of the population. Comparing this 6 item-index with the whole 33 item-index revealed that 65% of households were in the same quintiles, with a weighted kappa statistics of 0.76. For households in different quintiles, movement was generally limited to one quintile, with just 2% of households moving two or more quintiles. Conclusions: The proposed simple index is completely applicable in current Iran′s society. It can be used in different survey and studies. The development is

  18. Ecological Momentary Assessment in Behavioral Research: Addressing Technological and Human Participant Challenges

    Science.gov (United States)

    Shiffman, Saul; Music, Edvin; Styn, Mindi A; Kriska, Andrea; Smailagic, Asim; Siewiorek, Daniel; Ewing, Linda J; Chasens, Eileen; French, Brian; Mancino, Juliet; Mendez, Dara; Strollo, Patrick; Rathbun, Stephen L

    2017-01-01

    the 12-month study interval, adherence to completing EMA surveys was high, with 88.3% (66,978/75,888) completion of random assessments and around 90% (23,411/25,929 and 23,343/26,010) completion of time-contingent assessments, despite the duration of EMA data collection and challenges with implementation. Conclusions This work informed us of the necessary preliminary steps to plan and prepare a longitudinal study using smartphone technology and the critical elements to ensure participant engagement in the potentially burdensome protocol, which spanned 12 months. While this was a technology-supported and -programmed study, it required close oversight to ensure all elements were functioning correctly, particularly once human participants became involved. PMID:28298264

  19. Addressing the challenges of standalone multi-core simulations in molecular dynamics

    Science.gov (United States)

    Ocaya, R. O.; Terblans, J. J.

    2017-07-01

    Computational modelling in material science involves mathematical abstractions of force fields between particles with the aim to postulate, develop and understand materials by simulation. The aggregated pairwise interactions of the material's particles lead to a deduction of its macroscopic behaviours. For practically meaningful macroscopic scales, a large amount of data are generated, leading to vast execution times. Simulation times of hours, days or weeks for moderately sized problems are not uncommon. The reduction of simulation times, improved result accuracy and the associated software and hardware engineering challenges are the main motivations for many of the ongoing researches in the computational sciences. This contribution is concerned mainly with simulations that can be done on a "standalone" computer based on Message Passing Interfaces (MPI), parallel code running on hardware platforms with wide specifications, such as single/multi- processor, multi-core machines with minimal reconfiguration for upward scaling of computational power. The widely available, documented and standardized MPI library provides this functionality through the MPI_Comm_size (), MPI_Comm_rank () and MPI_Reduce () functions. A survey of the literature shows that relatively little is written with respect to the efficient extraction of the inherent computational power in a cluster. In this work, we discuss the main avenues available to tap into this extra power without compromising computational accuracy. We also present methods to overcome the high inertia encountered in single-node-based computational molecular dynamics. We begin by surveying the current state of the art and discuss what it takes to achieve parallelism, efficiency and enhanced computational accuracy through program threads and message passing interfaces. Several code illustrations are given. The pros and cons of writing raw code as opposed to using heuristic, third-party code are also discussed. The growing trend

  20. Social Justice and the Global Economy: New Challenges for Social Work in the 21st Century

    Science.gov (United States)

    Polack, Robert J.

    2004-01-01

    The globalization of the economy creates new challenges for social work in the arenas of social and economic justice. This article outlines social justice issues related to the debt crisis of the Global South and sweatshops. A presentation of colonial precursors is followed by a detailed examination of these global institutions with an emphasis on…

  1. Places to Go: Challenges to Multicultural Art Education in a Global Economy

    Science.gov (United States)

    Desai, Dipti

    2005-01-01

    This article examines the relationship between globalization and postmodern multicultural art education. The questions that drive my investigation are: What is the role of postmodern multiculturalism in this current phase of globalization and what challenges does globalization pose for multiculturalism? I explore the shifts in the field of art…

  2. The commercial marketing of healthy lifestyles to address the global child and adolescent obesity pandemic: prospects, pitfalls and priorities.

    Science.gov (United States)

    Kraak, Vivica I; Kumanyika, Shiriki K; Story, Mary

    2009-11-01

    Public- and private-sector initiatives to promote healthy eating and physical activity, called 'healthy lifestyles', are a relatively recent response to the global obesity pandemic. The present paper explores different views about marketing healthy lifestyles with a special emphasis on private-sector initiatives and public-private partnerships designed to reach young people. We discuss aspects of these initiatives and partnerships from three perspectives: (i) the potential for commercial marketing practices to have a favourable influence on reversing global obesity trends (termed prospects); (ii) unresolved dilemmas and challenges that may hinder progress (termed pitfalls); and (iii) the implementation and evaluation of coordinated and systematic actions (termed priorities) that may increase the likelihood that commercially marketed healthy-lifestyle initiatives and public-private partnerships can make a positive contribution to reverse the rise in overweight and obesity among young people globally.

  3. New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.

    Science.gov (United States)

    Hood, Leroy E; Omenn, Gilbert S; Moritz, Robert L; Aebersold, Ruedi; Yamamoto, Keith R; Amos, Michael; Hunter-Cevera, Jennie; Locascio, Laurie

    2012-09-01

    This White Paper sets out a Life Sciences Grand Challenge for Proteomics Technologies to enhance our understanding of complex biological systems, link genomes with phenotypes, and bring broad benefits to the biosciences and the US economy. The paper is based on a workshop hosted by the National Institute of Standards and Technology (NIST) in Gaithersburg, MD, 14-15 February 2011, with participants from many federal R&D agencies and research communities, under the aegis of the US National Science and Technology Council (NSTC). Opportunities are identified for a coordinated R&D effort to achieve major technology-based goals and address societal challenges in health, agriculture, nutrition, energy, environment, national security, and economic development.

  4. The urgent need for universities to comprehensively address global climate change across disciplines and programs.

    Science.gov (United States)

    Lemons, John

    2011-09-01

    I review the status of scientific, political, and moral problems of global climate change (GCC) and, based on lessons from environmental and sustainability programs in universities, demonstrate that universities have had a lethargic response to urgent needs to mitigate the problems. I explore reasons for the response, and conclude that there is an urgent need for comprehensive and wide-ranging change in universities to help mitigate GCC. My discussion is focused on those within universities as well as those in environmental professions regardless of their areas of specialization.

  5. Global Planted Forest Development: Opportunities,Challenges and Policy Choices

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In recent decades, there has seen a dramatic expansion of global planted forest area and their great impact on human life. It is reported in Forest Resource Assessment 2010 that the current area of global planted forests is about 264 million ha, representing only 7% of the total forest area but able to meet the two thirds of the global demand for logs. Planted forests can not only provide timber, fiber, fuel and non-wood forest products, but also contribute to carbon sequestration, restoration of degraded l...

  6. Assembling GHERG: Could "academic crowd-sourcing" address gaps in global health estimates?

    Science.gov (United States)

    Rudan, Igor; Campbell, Harry; Marušić, Ana; Sridhar, Devi; Nair, Harish; Adeloye, Davies; Theodoratou, Evropi; Chan, Kit Yee

    2015-06-01

    In recent months, the World Health Organization (WHO), independent academic researchers, the Lancet and PLoS Medicine journals worked together to improve reporting of population health estimates. The new guidelines for accurate and transparent health estimates reporting (likely to be named GATHER), which are eagerly awaited, represent a helpful move that should benefit the field of global health metrics. Building on this progress and drawing from a tradition of Child Health Epidemiology Reference Group (CHERG)'s successful work model, we would like to propose a new initiative - "Global Health Epidemiology Reference Group" (GHERG). We see GHERG as an informal and entirely voluntary international collaboration of academic groups who are willing to contribute to improving disease burden estimates and respect the principles of the new guidelines - a form of "academic crowd-sourcing". The main focus of GHERG will be to identify the "gap areas" where not much information is available and/or where there is a lot of uncertainty present about the accuracy of the existing estimates. This approach should serve to complement the existing WHO and IHME estimates and to represent added value to both efforts.

  7. Assembling GHERG: Could “academic crowd–sourcing” address gaps in global health estimates?

    Science.gov (United States)

    Rudan, Igor; Campbell, Harry; Marušić, Ana; Sridhar, Devi; Nair, Harish; Adeloye, Davies; Theodoratou, Evropi; Chan, Kit Yee

    2015-01-01

    In recent months, the World Health Organization (WHO), independent academic researchers, the Lancet and PLoS Medicine journals worked together to improve reporting of population health estimates. The new guidelines for accurate and transparent health estimates reporting (likely to be named GATHER), which are eagerly awaited, represent a helpful move that should benefit the field of global health metrics. Building on this progress and drawing from a tradition of Child Health Epidemiology Reference Group (CHERG)’s successful work model, we would like to propose a new initiative – “Global Health Epidemiology Reference Group” (GHERG). We see GHERG as an informal and entirely voluntary international collaboration of academic groups who are willing to contribute to improving disease burden estimates and respect the principles of the new guidelines – a form of “academic crowd–sourcing”. The main focus of GHERG will be to identify the “gap areas” where not much information is available and/or where there is a lot of uncertainty present about the accuracy of the existing estimates. This approach should serve to complement the existing WHO and IHME estimates and to represent added value to both efforts. PMID:26445671

  8. Poverty and Environmental Degradation Challenges within the Global Economy.

    Science.gov (United States)

    Mabogunje, Akin L.

    2002-01-01

    Since the end of the second World War, the link between deepening poverty and environmental degradation has increased in visibility despite the efforts of the United Nations and other international agencies. Focuses on globalization, poverty, and the environment. (DDR)

  9. The Challenges of Realization in a Global Civilization

    Directory of Open Access Journals (Sweden)

    James Winston Morris

    2011-12-01

    Full Text Available The contemporary historical situation suggests fascinating parallels with that period of the 13th/7th century when the massive destruction of the Mongol invasions opened the way for popular new forms of Islamic life and practice that eventually spread Islam throughout Asia. Today, as in earlier periods of dramatic upheaval, we can witness those processes of inspiration and awakening that give rise to the spiritual pathways of future centuries, through each soul’s gradual discovery of its unique challenges and demands of ihsan.One way of describing this transformation, to use the Qur’anic language adapted by Ibn ‘Arabi, is in the terms of the process of spiritual realization (tahqīq by which people discover their guiding inner relationship to those divine qualities or “Names” that eventually come to define the meaning and purpose of their lives. Through our life long movement of service (‘ibda to the “Lord” (rabb constituted by each divine Name, the transformation of the soul follows a familiar, naturally ascending trajectory. It begins with a curiosity drawing us toward some particular dimension of the Real (al-Haqq; then a compelling striving leading to heightened discipline and awareness; and ultimately to the creative manifestation of that devotion through the appropriate means of  teaching, communication, and new communities of fellow- seekers—the Qur’anic “servants of  the All-Merciful”—that slowly emerge from this shared spiritual work of  devotion, discovery and creative response. Here we point to some ways this process of civilizational renewal is unfolding around the world, focusing on three of  the most far-reaching of those divine Names: the “servants of the All-Wise” (al-Hakīm, in their exploring and deciphering the infinite Signs of  God’s Wisdom “on the horizons”, in all of  the sciences of nature and society; to those muhsinūn and “servants of  the Beautiful” (al-Jamīl whose

  10. The Minamata Convention on Mercury: attempting to address the global controversy of dental amalgam use and mercury waste disposal.

    Science.gov (United States)

    Mackey, Tim K; Contreras, John T; Liang, Bryan A

    2014-02-15

    In October 2013, a new international binding treaty instrument called the Minamata Convention on Mercury opened for signature in Minamata City, Japan, the site of arguably the worst public health and environmental disaster involving mercury contamination. The treaty aims to curb the significant health and environmental impacts of mercury pollution and includes provisions addressing the mining, export and import, storage, and waste management of products containing mercury. Importantly, a provision heavily negotiated in the treaty addresses the use of dental fillings using mercury amalgam, an issue that has been subject to decades of global controversy. Though use of dental amalgam is widespread and has benefits, concerns have been raised regarding the potential for human health risk and environmental damage from emissions and improper waste management. While the Minamata Convention attempts to address these issues by calling for a voluntary phase-down of dental amalgam use and commitment to other measures, it falls short by failing to require binding and measurable targets to achieve these goals. In response, the international community should begin exploring ways to strengthen the implementation of the dental amalgam treaty provisions by establishing binding phase-down targets and milestones as well as exploring financing mechanisms to support treaty measures. Through strengthening of the Convention, stakeholders can ensure equitable access to global oral health treatment while also promoting responsible environmental stewardship.

  11. EU Failing FAO Challenge to Improve Global Food Security.

    Science.gov (United States)

    Smyth, Stuart J; Phillips, Peter W B; Kerr, William A

    2016-07-01

    The announcement that the European Union (EU) had reached an agreement allowing Member States (MS) to ban genetically modified (GM) crops confirms that the EU has chosen to ignore the food security challenge issued to the world by the Food and Agriculture Organization of the United Nations (FAO) in 2009. The FAO suggests that agricultural biotechnology has a central role in meeting the food security challenge. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Struggles Against Bilateral FTAs: Challenges for Transnational Global Justice Activism

    Directory of Open Access Journals (Sweden)

    Aziz Choudry

    2012-11-01

    Full Text Available The past decade has seen major movements and mobilizations against the new crop of bilateral free trade and investment agreements being pursued by governments in the wake of the failure of global (World Trade Organization and regional (e.g. Free Trade Area of the Americas negotiations, and the defeat of an attempted Multilateral Agreement on Investment in the 1990s.  However, in spite of much scholarly, non-governmental organization (NGO and activist focus on transnational global justice activism, many of these movements, such as the major multi-sectoral popular struggle over the recently-concluded US-Korea Free Trade Agreement, are hardly acknowledged in North America and Europe.  With a shift in emphasis pushing liberalization and deregulation of trade and investment increasingly favouring lower-profile bilateral agreements, this article maps the resistance movements to these latest shifts in global free market capitalist relations and discusses the disconnect between these (mainly Southern struggles and dominant scholarly and NGO conceptions of global justice and the global justice movement as well as questions of knowledge production arising from these movements.

  13. Free-trade agreements: challenges for global health

    Directory of Open Access Journals (Sweden)

    Helena Ribeiro

    2015-01-01

    Full Text Available In this study new free-trade agreements are discussed, which are based on the breaking down of tariff and technical barriers and normally exclude most of the poorest countries in the world. Considering the current context of economic globalization and its health impacts, seven controversial points of these treaties and their possible implications for global public health are presented, mainly regarding health equity and other health determinants. Finally, this research proposes a greater social and health professionals participation in the formulation and discussion of these treaties, and a deeper insertion of Brazil in this important international agenda.

  14. Free-trade agreements: challenges for global health.

    Science.gov (United States)

    Ribeiro, Helena

    2015-01-01

    In this study new free-trade agreements are discussed, which are based on the breaking down of tariff and technical barriers and normally exclude most of the poorest countries in the world. Considering the current context of economic globalization and its health impacts, seven controversial points of these treaties and their possible implications for global public health are presented, mainly regarding health equity and other health determinants. Finally, this research proposes a greater social and health professionals participation in the formulation and discussion of these treaties, and a deeper insertion of Brazil in this important international agenda.

  15. LCA of emerging technologies: addressing high uncertainty on inputs' variability when performing global sensitivity analysis.

    Science.gov (United States)

    Lacirignola, Martino; Blanc, Philippe; Girard, Robin; Pérez-López, Paula; Blanc, Isabelle

    2017-02-01

    In the life cycle assessment (LCA) context, global sensitivity analysis (GSA) has been identified by several authors as a relevant practice to enhance the understanding of the model's structure and ensure reliability and credibility of the LCA results. GSA allows establishing a ranking among the input parameters, according to their influence on the variability of the output. Such feature is of high interest in particular when aiming at defining parameterized LCA models. When performing a GSA, the description of the variability of each input parameter may affect the results. This aspect is critical when studying new products or emerging technologies, where data regarding the model inputs are very uncertain and may cause misleading GSA outcomes, such as inappropriate input rankings. A systematic assessment of this sensitivity issue is now proposed. We develop a methodology to analyze the sensitivity of the GSA results (i.e. the stability of the ranking of the inputs) with respect to the description of such inputs of the model (i.e. the definition of their inherent variability). With this research, we aim at enriching the debate on the application of GSA to LCAs affected by high uncertainties. We illustrate its application with a case study, aiming at the elaboration of a simple model expressing the life cycle greenhouse gas emissions of enhanced geothermal systems (EGS) as a function of few key parameters. Our methodology allows identifying the key inputs of the LCA model, taking into account the uncertainty related to their description.

  16. Adult Education, Lifelong Learning, Global Knowledge: The Challenge and the Potential.

    Science.gov (United States)

    Ramdas, Lalita

    1997-01-01

    Reflections on the Fifth International Conference on Adult Education address continuing social inequities, negative effects of globalization, adult education's role in empowerment and human rights education, and the importance of emphasizing the fundamental interconnectedness of all people. (SK)

  17. Global surgery for pediatric hydrocephalus in the developing world: a review of the history, challenges, and future directions.

    Science.gov (United States)

    Muir, Ryan T; Wang, Shelly; Warf, Benjamin C

    2016-11-01

    OBJECTIVE Pediatric hydrocephalus is one of the most common neurosurgical conditions and is a major contributor to the global burden of surgically treatable diseases. Significant health disparities exist for the treatment of hydrocephalus in developing nations due to a combination of medical, environmental, and socioeconomic factors. This review aims to provide the international neurosurgery community with an overview of the current challenges and future directions of neurosurgical care for children with hydrocephalus in low-income countries. METHODS The authors conducted a literature review around the topic of pediatric hydrocephalus in the context of global surgery, the unique challenges to creating access to care in low-income countries, and current international efforts to address the problem. RESULTS Developing countries face the greatest burden of pediatric hydrocephalus due to high birth rates and greater risk of neonatal infections. This burden is related to more general global health challenges, including malnutrition, infectious diseases, maternal and perinatal risk factors, and education gaps. Unique challenges pertaining to the treatment of hydrocephalus in the developing world include a preponderance of postinfectious hydrocephalus, limited resources, and restricted access to neurosurgical care. In the 21st century, several organizations have established programs that provide hydrocephalus treatment and neurosurgical training in Africa, Central and South America, Haiti, and Southeast Asia. These international efforts have employed various models to achieve the goals of providing safe, sustainable, and cost-effective treatment. CONCLUSIONS Broader commitment from the pediatric neurosurgery community, increased funding, public education, surgeon training, and ongoing surgical innovation will be needed to meaningfully address the global burden of untreated hydrocephalus.

  18. CHALLENGES OF INTERNATIONAL STANDARDS ON AUDITING IN GLOBAL CRISIS CONTEXT

    Directory of Open Access Journals (Sweden)

    Daniel Botez

    2008-12-01

    Full Text Available The financial crisis that broke out in summer 2007 is striking in its sheer magnitude, the speed of its contagion to the global financial sphere, as well as its persistence. These factors make it on the most impressive and unprecedented events in recent financial history.

  19. The Global Challenge of Antimicrobial Resistance: Insights from Economic Analysis

    Directory of Open Access Journals (Sweden)

    Richard J. Zeckhauser

    2010-08-01

    Full Text Available The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.The prevalence of antimicrobial resistance (AR limits the therapeutic options for treatment of infections, and increases the social benefit from disease prevention. Like an environmental resource, antimicrobials require stewardship. The effectiveness of an antimicrobial agent is a global public good. We argue for greater use of economic analysis as an input to policy discussion about AR, including for understanding the incentives underlying health behaviors that spawn AR, and to supplement other methods of tracing the evolution of AR internationally. We also discuss integrating antimicrobial stewardship into global health governance.

  20. Global Climate Change:A Monumental Mitigation Challenge

    Science.gov (United States)

    A holistic view of long-term sustainability cannot ignore humanity’s ever-growing demands on fossil fuels, water, and other finite geological resources. Figure 1 (Princiotta et. al., 2014) illustrates the key factors that are responsible for potentially unsustainable global impac...

  1. Global Governance of Food Production and Consumption. Issues and Challenges

    NARCIS (Netherlands)

    Oosterveer, P.J.M.

    2007-01-01

    The provision of food is undergoing radical transformations throughout the global community. Peter Oosterveer argues that, as a consequence, conventional national governmental regulations can no longer adequately respond to existing and emerging food risks and to environmental concerns. This book ex

  2. Governing Environmental Flows : Global Challenges to Social Theory

    NARCIS (Netherlands)

    Spaargaren, G.; Mol, A.P.J.; Buttel, F.H.

    2006-01-01

    Globalization and the changing role of the nation-state call for new approaches to environmental governance and new ways to conceptualize it. Recent developments in sociology--seen in the work of John Urry, Manuel Castells, and others--show how social theory can be made less static, more fluid, and

  3. The challenge of the global elimination of iodine deficiency disorders.

    NARCIS (Netherlands)

    Haar, van der F.

    1997-01-01

    Most nations of the world are well positioned for success in their pursuit of the virtual elimination of iodine deficiency disorders (IDD) by the year 2000. In 1990 at the World Summit for Children, Heads of State and Government had agreed on this global goal and in 1992 at the International Confere

  4. [Multidrug-resistant tuberculosis: challenges of a global emergence].

    Science.gov (United States)

    Comolet, T

    2015-10-01

    Drug-resistant tuberculosis, in particular Multi-Drug Resistant (MDR-TB) is an increasing global concern and a major burden for some developing countries, especially the BRICS. It is assumed that every year roughly 350 000 new MDR-TB cases occur in the world, on average in 20.5% of TB patients that have been previously treated but also in 3.5% of persons that have never been on TB treatment before. The global distribution of cases is very heterogeneous and is now better understood thanks to a growing number of specific surveys and routine surveillance systems: incidence is much higher in southern Africa and in all countries formerly part of the USSR. Countries with weak health systems and previously inefficient TB control programs are highly vulnerable to MDR epidemics because program failures do help creating, maintaining and spreading resistances. Global response is slowly rolled out and diagnosis capacities are on the rise (mostly with genotypic methods) but adequate and successful treatment and care is still limited to a minority of global cases. From a public health perspective the MDR-TB growing epidemics will not be controlled merely by the introduction of few new antibiotics because it is also linked to patient's compliance and adequate case management supported by efficient TB program. In depth quality improvement will only be achieved after previous errors are thoroughly analyzed and boldly corrected.

  5. Global Governance of Food Production and Consumption. Issues and Challenges

    NARCIS (Netherlands)

    Oosterveer, P.J.M.

    2007-01-01

    The provision of food is undergoing radical transformations throughout the global community. Peter Oosterveer argues that, as a consequence, conventional national governmental regulations can no longer adequately respond to existing and emerging food risks and to environmental concerns. This book ex

  6. The Global Classroom and the Educational Challenge of Cultural Diversity

    Science.gov (United States)

    Moyer, Sonja S.

    2010-01-01

    Change in education is not going away; instead, it seems to be increasing exponentially. Technology has been the catalyst, and the changes with the greatest impact on education are the location and size of the classroom. The challenges associated with these changes involve working with students from potentially an unlimited number of countries and…

  7. The Global Classroom and the Educational Challenge of Cultural Diversity

    Science.gov (United States)

    Moyer, Sonja S.

    2010-01-01

    Change in education is not going away; instead, it seems to be increasing exponentially. Technology has been the catalyst, and the changes with the greatest impact on education are the location and size of the classroom. The challenges associated with these changes involve working with students from potentially an unlimited number of countries and…

  8. Science Education and Challenges of Globalization in Igbo Nation

    Science.gov (United States)

    Ezeudu, F. O.; Nkokelonye, C. U.; Adigwe, J. C.

    2013-01-01

    This paper reviewed the scientific contents in Igbo culture. Description of the Igbos who constitutes an ethnic group occupying southeastern Nigeria was made. It x-rayed the pre-colonial, colonial, and post-colonial culture of Igbo people and identified the scientific cultural activities, which can be harnessed to meet the challenges of modern day…

  9. LHC Computing Centres Join Forces for Global Grid Challenge

    CERN Multimedia

    2005-01-01

    Today, in a significant milestone for scientific grid computing, eight major computing centres successfully completed a challenge to sustain a continuous data flow of 600 megabytes per second (MB/s) on average for 10 days from CERN in Geneva, Switzerland to seven sites in Europe and the US

  10. Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor Vulnerability Assessments (Final Report)

    Science.gov (United States)

    EPA announced the availability of the final report, Aquatic Ecosystems and Global Change: The Challenges of conducting Multi-Stressor Global Change Vulnerability Assessments. This report investigates the issues and challenges associated with identifying, calculating, and ...

  11. Makerere University College of Health Sciences’ role in addressing challenges in health service provision at Mulago National Referral Hospital

    Directory of Open Access Journals (Sweden)

    Sekandi Juliet

    2011-03-01

    Full Text Available Abstract Background Mulago National Referral Hospital (MNRH, Uganda’s primary tertiary and teaching hospital, and Makerere University College of Health Sciences (MakCHS have a close collaborative relationship. MakCHS students complete clinical rotations at MNRH, and MakCHS faculty partner with Mulago staff in clinical care and research. In 2009, as part of a strategic planning process, MakCHS undertook a qualitative study to examine care and service provision at MNRH, identify challenges, gaps, and solutions, and explore how MakCHS could contribute to improving care and service delivery at MNRH. Methods Key informant interviews (n=23 and focus group discussions (n=7 were conducted with nurses, doctors, administrators, clinical officers and other key stakeholders. Interviews and focus groups were tape recorded and transcribed verbatim, and findings were analyzed through collaborative thematic analysis. Results Challenges to care and service delivery at MNRH included resource constraints (staff, space, equipment, and supplies, staff inadequacies (knowledge, motivation, and professionalism, overcrowding, a poorly functioning referral system, limited quality assurance, and a cumbersome procurement system. There were also insufficiencies in the teaching of professionalism and communication skills to students, and patient care challenges that included lack of access to specialized services, risk of infections, and inappropriate medications. Suggestions for how MakCHS could contribute to addressing these challenges included strengthening referral systems and peripheral health center capacity, and establishing quality assurance mechanisms. The College could also strengthen the teaching of professionalism, communication and leadership skills to students, and monitor student training and develop courses that contribute to continuous professional development. Additionally, the College could provide in-service education for providers on professionalism

  12. USGCRP assessments: Meeting the challenges of climate and global change

    Science.gov (United States)

    Dickinson, T.; Kuperberg, J. M.

    2016-12-01

    The United States Global Change Research Program (USGCRP) is a confederation of the research arms of 13 Federal departments and agencies. Its mission is to build a knowledge base that informs human responses to climate and global change through coordinated and integrated Federal programs of research, education, communication, and decision support. USGCRP has supported several initiatives to promote better understanding of climate change impacts on health, support responses, and build on the progress of the 2014 National Climate Assessment. Most recently, USGCRP released a new report, "The Impacts of Climate Change on Human Health: A Scientific Assessment". This presentation will provide an overview of USGCRP, highlight the importance of assessments, and introduce ways in which assessment findings and underlying data can be translated into critical tools to build resilience.

  13. Global and Domestic Challenges Confronting Buddhist Institutions in Japan

    Directory of Open Access Journals (Sweden)

    John Nelson

    2015-02-01

    Full Text Available With the rise of globalization in the past twenty years, the positioning of religious belief and activity worldwide has become increasingly complicated due to new information technologies, immigration flows, corporate restructuring and transnational finance. This paper identifies five factors that not only characterize late modern societies but also create conditions to which religions must adapt, or ignore at their peril. Using Buddhist temples, priests, and their surrounding communities in Japan as case studies, the paper traces how social forces such as 1 a “crisis of orientation,” 2 corporate and bureaucratic restructuring, 3 consumer culture, 4 individualization within a “risk” society, and 5 experimental approaches to spirituality impact religious practice and institutions. Without a perspective that incorporates the global into the local (but still acknowledges the power of individual agency, our analysis of religious activities remains parochial and sociocentric.

  14. MEDICAL TOURISM INDUSTRY CHALLENGES IN THE CONTEXT OF GLOBALIZATION

    Directory of Open Access Journals (Sweden)

    Carmen, IORDACHE

    2014-07-01

    Full Text Available Medical tourism is not a new concept, even though there is still no international consensus on the name of this phenomenon that is manifesting itself for thousands of years. It is defined by moving patients in various countries to obtain medical care and combined with certain tourist facilities. Increased flow of patients seeking treatment abroad is a global phenomenon linked to economic growth which generates income revenue and a high level of education. Internationally, medical tourism increases by 20% per year, global market for medical tourism at present is estimated to be about 100 billion dollars. This study tries to highlight a conceptual analysis of medical tourism, the targeting of medical tourism flows and major destinations and the proposed tourism development strategies based on the experience of several countries medical.

  15. The Use of Kanban to Alleviate Collaboration and Communication Challenges of Global Software Development

    National Research Council Canada - National Science Library

    Maureen Tanner; Marcelo Edgar Dauane

    2017-01-01

    Aim/Purpose: This paper aims to describe how various Kanban elements can help alleviate two prominent types of challenges, communication and collaboration in Global Software Development (GSD). Background...

  16. Globalization of S&T: Key Challenges Facing DOD

    Science.gov (United States)

    2012-02-01

    breadth and pace of innovation . We are now experiencing a global shift to a more level playing field among nations; demographics, economics, and...The country’s status included predominance in most fields of science and technology (S&T), as well as a phenomenal breadth and pace of innovation . We...capita and using PPP rates over the period 2005–2050. 13 The World in 2050: Beyond the BRICs —A Broader

  17. International expansion of Chinese multinationals: the new challenge of globalization

    OpenAIRE

    2010-01-01

    Over the last few years, a new generation of Chinese multinationals has set out to conquer global markets, featuring major international acquisitions that were unthinkable until very recently. This work seeks to analyze the nature of this emerging phenomenon, illustrating the reasons behind the international expansion of Chinese multinationals, the factors that facilitate and hinder this process, the entry modes that they use and the strategic implications for Western companies of their sudde...

  18. Injuries and violence: a global public health challenge

    OpenAIRE

    2012-01-01

    Injuries and violence are a significant cause of mortality and physical disability. Injuries killed five million people worldwide each year [1]. The level of this dilemma, however, differs significantly by age, sex, region and economic development [2]. Globally, road traffic injury mortalities, self-inflicted injury mortality and interpersonal violence, war, drowning, and exposure to fire are the leading cause of deaths among people aged 15-44 years [3]. This special issue aims to assess the ...

  19. E-waste management as a global challenge (introductory chapter)

    OpenAIRE

    Mihai, Florin-Constatin; Gnoni, Maria-Grazia

    2016-01-01

    International audience; Waste Electrical and Electronic Equipment management (E-waste or WEEE) is a crucial issue in the solid waste management sector with global interconnections between well-developed, transitional and developing countries. Consumption society and addiction to technology dictate the daily life in high and middle-income countries where population consumes large amounts of EEE products (electrical and electronic equipment) which sooner become e-waste. This fraction is a fast-...

  20. Food security for Africa: an urgent global challenge

    OpenAIRE

    Sasson Albert

    2012-01-01

    Abstract In 2012, food insecurity is still a major global concern as 1 billion people are suffering from starvation, under-, and malnutrition, and the Food and Agriculture Organization of the United Nations (FAO) has concluded that we are still far from reaching millennium development goal (MDG) number 1: to halve extreme poverty and hunger by 2015. In sub-Saharan Africa, the number of people suffering from hunger is estimated at 239 million, and this figure could increase in the near future....

  1. Addressing the Photometric Calibration Challenge: Explicit Determination of the Instrumental Response and Atmospheric Response Functions, and Tying it All Together.

    Science.gov (United States)

    Stubbs, C. W.; Tonry, J. L.

    2016-05-01

    Photometric calibration is currently the dominant source of systematic uncertainty in exploiting type Ia supernovae to determine the nature of the dark energy. We review our ongoing program to address this calibration challenge by performing measurements of both the instrumental response function and the optical transmission function of the atmosphere. A key aspect of this approach is to complement standard star observations by using NIST-calibrated photodiodes as a metrology foundation for optical flux measurements. We present our first attempt to assess photometric consistency between synthetic photometry and observations, by comparing predictions based on a NIST-diode-based determination of the PanSTARRS-1 instrumental response and empirical atmospheric transmission measurements, with fluxes we obtained from observing spectrophotometric standards.

  2. Addressing the Photometric Calibration Challenge: Explicit Determination of the Instrumental Response and Atmospheric Response Functions, and Tying it All Together

    CERN Document Server

    Stubbs, Christopher W

    2012-01-01

    Photometric calibration is currently the dominant source of systematic uncertainty in exploiting type Ia supernovae to determine the nature of the dark energy. We review our ongoing program to address this calibration challenge by performing measurements of both the instrumental response function and the optical transmission function of the atmosphere. A key aspect of this approach is to complement standard star observations by using NIST-calibrated photodiodes as a metrology foundation for optical flux measurements. We present our first attempt to assess photometric consistency between synthetic photometry and observations, by comparing predictions based on a NIST-diode-based determination of the PanSTARRS-1 instrumental response and empirical atmospheric transmission measurements, with fluxes we obtained from observing spectrophotometric standards.

  3. Contemporary Business Education: a Solution for Global Leadership Challenges

    Directory of Open Access Journals (Sweden)

    Tudor Cristian Ţiclău

    2014-08-01

    Full Text Available Education and professional development is considered central issues in civil service development and public administration reform. While this may be true, the content of such programs bears equal influence in skill acquirement, which in turn, has an impact on managerial performance (Perry, 1989. The contemporary economic and social environment poses numerous and complex challenges to public leaders, who need to be equipped with the adequate set of skills and competencies in order to have a proper response. The present paper aims to find out the whether the current educational programs from the business field can be a solution for preparing the next generation of public (and private leaders. My argument is that the latest developments in public management reform (New Public Management, Good Governance and Public Entrepreneurship combined with new demands for effectiveness, efficiency and high quality public services could increase the relevance of such programs. In support for this I presented a series of research results that point to a set of common leadership challenges that transcend the public-private divide. Finally I explored the offerings of the top 5 MBA programs in the world to see whether this is reflected in their educational programs. Not surprisingly, three out of the five programs analysed offer dual degree programs that combine business and public management education as a solution for the leadership challenges that lay ahead.

  4. Social justice and the global economy: new challenges for social work in the 21st century.

    Science.gov (United States)

    Polack, Robert J

    2004-04-01

    The globalization of the economy creates new challenges for social work in the arenas of social and economic justice. This article outlines social justice issues related to the debt crisis of the Global South and sweatshops. A presentation of colonial precursors is followed by a detailed examination of these global institutions with an emphasis on the vulnerability, disempowered status, and exploitation of poor people of the Global South. Connections with global inequities in wealth, income, and the distribution of resources are made explicit. The article explores domestic social justice problems as possible points of connection with these issues. Finally, the authors give recommendations for social work education, advocacy, and activism.

  5. One Health: The global challenge of epidemic and endemic leishmaniasis

    Directory of Open Access Journals (Sweden)

    Day Michael J

    2011-10-01

    Full Text Available Abstract 'One Health' proposes the unification of medical and veterinary sciences with the establishment of collaborative ventures in clinical care, surveillance and control of cross-species disease, education, and research into disease pathogenesis, diagnosis, therapy and vaccination. The concept encompasses the human population, domestic animals and wildlife, and the impact that environmental changes ('environmental health' such as global warming will have on these populations. Visceral leishmaniasis is a perfect example of a small companion animal disease for which prevention and control might abolish or decrease the suffering of canine and human patients, and which aligns well with the One Health approach. In this review we discuss how surveillance for leishmaniases is undertaken globally through the control of anthroponootic visceral leishmaniasis (AVL and zoonotic visceral leishmaniasis (ZVL. The ZVL epidemic has been managed to date by the culling of infected dogs, treatment of human cases and control of the sandfly vector by insecticidal treatment of human homes and the canine reservoir. Recently, preventive vaccination of dogs in Brazil has led to reduction in the incidence of the canine and human disease. Vaccination permits greater dog owner compliance with control measures than a culling programme. Another advance in disease control in Africa is provided by a surveillance programme that combines remote satellite sensing, ecological modelling, vector surveillance and geo-spatial mapping of the distribution of vectors and of the animal-to-animal or animal-to-human pathogen transmission. This coordinated programme generates advisory notices and alerts on emerging infectious disease outbreaks that may impede or avoid the spreading of visceral leishmaniasis to new areas of the planet as a consequence of global warming.

  6. Multilingual trends in a globalized world prospects and challenges

    CERN Document Server

    Singh, Navin Kumar

    2013-01-01

    This book presents evolving language education trends by drawing examples and case studies from around the world. Over the past few decades, significant economic and political changes have taken place around the world which have had a significant impact on language teaching and learning practices across the globe. With globalization, the focus of language education has shifted from monolingualism towards bilingualism and multilingualism, in that multilingual practices have become the norm rather than the exception in most parts of the world. This book brings together some of latest controversi

  7. Five challenges for stochastic epidemic models involving global transmission

    Directory of Open Access Journals (Sweden)

    Tom Britton

    2015-03-01

    Full Text Available The most basic stochastic epidemic models are those involving global transmission, meaning that infection rates depend only on the type and state of the individuals involved, and not on their location in the population. Simple as they are, there are still several open problems for such models. For example, when will such an epidemic go extinct and with what probability (questions depending on the population being fixed, changing or growing? How can a model be defined explaining the sometimes observed scenario of frequent mid-sized epidemic outbreaks? How can evolution of the infectious agent transmission rates be modelled and fitted to data in a robust way?

  8. Addressing the next challenges: A summary of the 22nd international symposium on hepatitis C virus and related viruses.

    Science.gov (United States)

    Baumert, Thomas F; Schuster, Catherine; Cosset, François-Loïc; Dubuisson, Jean; Hofmann, Maike; Tautz, Norbert; Zeisel, Mirjam B; Thimme, Robert

    2016-04-01

    Following the discovery of the hepatitis C virus (HCV) more than 25 years ago the field has succeeded to develop methods that have changed the safety of blood products, understand the molecular virology, epidemiology and clinical disease of HCV, and identify specific targets for the development of direct-acting antivirals for HCV cure. Nevertheless, major clinical and scientific challenges remain: therapy is still only available to a fraction of infected patients worldwide and many patients remain undiagnosed and/or live in countries where therapy is unattainable. An urgently needed HCV vaccine to eradicate infection remains still elusive. Scientifically, major questions remain regarding the life cycle, pathogenesis and mechanisms of viral clearance and persistence. Addressing these challenges, this meeting report reviews key findings of the 22nd International Symposium on Hepatitis C Virus and Related Viruses in Strasbourg, France from October 9 to 13, 2015. Copyright © 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

  9. New Methods to Address Old Challenges: The Use of Administrative Data for Longitudinal Replication Studies of Child Maltreatment.

    Science.gov (United States)

    Hurren, Emily; Stewart, Anna; Dennison, Susan

    2017-09-15

    Administrative data are crucial to the "big data" revolution of social science and have played an important role in the development of child maltreatment research. These data are also of value to administrators, policy makers, and clinicians. The focus of this paper is the use of administrative data to produce and replicate longitudinal studies of child maltreatment. Child protection administrative data have several advantages. They are often population-based, and allow longitudinal examination of child maltreatment and complex multi-level analyses. They also allow comparison across subgroups and minority groups, remove burden from individuals to disclose traumatic experiences, and can be less biased than retrospective recall. Finally, they can be linked to data from other agencies to explore comorbidity and outcomes, and are comparatively cost and time effective. The benefits and challenges associated with the use of administrative data for longitudinal child maltreatment research become magnified when these data are used to produce replications. Techniques to address challenges and support future replication efforts include developing a biographical understanding of the systems from which the data are drawn, using multiple data sources to contextualize the data and research results, recognizing and adopting various approaches to replication, and documenting all data coding and manipulation processes. These techniques are illustrated in this paper via a case study of previous replication work.

  10. Global Character of International Labour Migration: Challenges and Objectives for Higher Education in World Context

    Science.gov (United States)

    Zhuravska, Nina

    2016-01-01

    The article deals with analysis of challenges and objectives for higher education in the context of globalization: the forming of international labour market proves the fact that the process of international integration is affecting economy and technology as well as social and labour relations that are becoming more and more global. The…

  11. 76 FR 55060 - Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor...

    Science.gov (United States)

    2011-09-06

    ... AGENCY Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor... of Availability. SUMMARY: EPA is releasing a final report entitled, Aquatic Ecosystems, Water Quality... and aquatic ecosystems across the United States to the potential impacts of global change. Using a...

  12. Conducting Community Research in Rural China -Addressing the Methodological Challenges of Recruiting Participants in Rapidly Changing Social Environments.

    Science.gov (United States)

    Dai, Jing; Chiu, Helen F K; Hou, Zai-Jin; Caine, Eric D

    2012-06-01

    BACKGROUND: The paper addressed a unique challenge for public health and community research in rural China, i.e., the very large percentage of young adults that comprises a highly mobile working population that has been an essential component of the country's economic transformation. Fluid local demographic patterns potentially have a substantial impact on sample representativeness and data validity. METHODS: This report is based upon a cross sectional survey with face-to-face interviews of residents aged 16-34 years in rural communities of Mianyang, Sichuan Province, China. Two waves of fieldwork and other strategies were adopted in response to recruitment challenges. RESULTS: 1654 of 3008 potential participants took part in the study; this constituted 98% of those individuals approached and 55% of the persons enumerated in the local household registration system (hukou). Analyses revealed substantial differences among those who were interviewed during September and October 2005, versus those seen during the Chinese Lunar New Year of 2006 when many migrant workers and students returned to their homes. Both groups together differed from those who were unavailable during either recruiting episode. DISCUSSION AND CONCLUSIONS: We discuss potential responses to associated methodological challenges, including, (1) permanent hukou mismatches; (2) temporary hukou mismatches; (3) difficulties faced by potential participants to fully understand the purpose of research, the informed consent process, and specific research questions; and (4) appreciation of the importance of local social networks, as they pertain in particular to rural China. These findings underscore that there may be a need to make "on-the-ground" adjustments to varying local conditions to maximize sample representativeness and data validity.

  13. Global challenges and perspectives of marketing of healthy food products

    Directory of Open Access Journals (Sweden)

    Mitić Sanja

    2012-01-01

    Full Text Available This paper deals with global trends of healthy food market growth, Serbian export potential as well as with the importance and role of positioning and other marketing strategies in this field. Secondary data will be used for identifying characteristics and range of healthy food market on a global level and key segments. In that context, the economic importance and export potential of this sector in Serbia will be discussed. Food sector accounts for high percentage of total Serbian export. Yet, those products are of low added value, neither branded nor packed. In order to position producers of healthy food on an international market successfully, strength and weaknesses of domestic production and export will be identified as well as measures for its promotion. In this paper, literature review in field of food positioning and marketing will be presented. Various positioning strategies of healthy food will be discussed from the aspect of branding, country of origin image, marketing mix instruments, with special emphasis on promotion and product labelling. Special part of paper will be dedicated to specific aspects of buying and food consumption behaviour. This behaviour is under the influence of numerous factors, both personal and sociodemographic, which will be analyzed in order to identify adequate positioning strategies. At the end, recommendations for successfully healthy food positioning on an international market will be given. We will present ways of improving marketing strategies regarding exploiting identified chances on an international market.

  14. Zika virus: Global health challenge, threat and current situation.

    Science.gov (United States)

    Aziz, Hafsa; Zia, Aadarash; Anwer, Amania; Aziz, Muneeba; Fatima, Shazia; Faheem, Muhammad

    2017-06-01

    ZIKV has emerged as grave global health issue in the past few years. ZIKV was firstly isolated in 1947 from a rhesus sentinel monkey in the Zika forest in Uganda. It is usually transmitted by the bite of infected mosquitoes and infects skin fibroblasts, skin keratinocytes, etc. ZIKV until now was under reported because of its clinical similarity with the dengue and chikungunya. It is usually spread through the course of the sylvatic cycle. In this cycle, the virus or pathogen lifespan is spent between the wild animal and vectors. The intrinsic incubation period is not yet fully known but it is observed that the very first symptoms of ZIKV infection can appear or develop within 3-12 days of time period and usually subside within 7 days of time. There is a strong relationship between prenatal Zika virus infection and microcephaly; other serious brain anomalies to the infant or newborn are Guillain-Barré syndrome. To date no vaccines are available for ZIKV prevention hence only symptomatic treatment is recommended in infected patients. Usually ZIKV is detected by serologic (IgM ELISA), plaque reduction neutralization test (PRNT) along with in-house" molecular techniques (RT-PCR). ZIKV infection being imminent global health issue warrants strong protective measures to prevent it from becoming an epidemic. Early detection and prevention is the key to tackle this grave potential health hazard. J. Med. Virol. 89:943-951, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  15. GEOPOLITICS - A NEW FRAMEWORK OF ANALYSIS: GLOBAL CHALLENGES AND PERSPECTIVES

    Directory of Open Access Journals (Sweden)

    Laura Cătălina PAȘCU

    2015-04-01

    Full Text Available Geopolitics born at the end of the 19th century and reborn at the end of the 20th century, from the need to explain certain issues arising out of the general evolution of human society and the growing influence of permanent politico-economic changes on the human consciousness and the entire system of socio-political life and culture. Also, geopolitics gives us the opportunity to reflect on the manifestation and evolution of power relations within a particular historical period, to assess and track changes and trends in the current system of international relations, giving us indicators and analytical methods about the reality of international relations. The relations of competition versus cooperation between international actors have changed gradually in the 21st century; however, development cooperation can provide solutions or opportunities for defining global problems. Globalization creates a new framework in security and international relations also introduced the geo-economics perspectives to assumed new found geopolitical importance at the outset of the twenty-first century.

  16. The global market for oilseeds: prospects and challenges for Morocco

    Directory of Open Access Journals (Sweden)

    Gosselet Nathalie

    2014-03-01

    Full Text Available The global market for oilseeds, grains, vegetable oil and oilseed meal is a complex market which is growing at a very fast pace, and which is characterized by the large volume of production which is traded between countries. Offer is geographically constrained in this market: there are few exporting countries and these are mainly situated on the American continent. Demand on the other hand is more widespread, although highest in Asiatic countries, China in particular. As a result, small importing countries, like Morocco, are in a vulnerable position, and take the full brunt of price volatility. In the 90s, Moroccan oilseed production was relatively high, unfortunately production dropped over the years, and Morocco must now buy vegetable oil and proteins on the global market. Reviving oilseed production in Morocco would considerably help the country and provide numerous benefits, such as food security, improving the country’s trade balance, and enhancing the agronomic management of land thanks to the introduction of break crops. Finally, it would also boost the entire agricultural sector and help increase the income of farmers.

  17. Knowledge capabilities for sustainable development in global classrooms - local challenges

    Directory of Open Access Journals (Sweden)

    Elise Anderberg

    2011-01-01

    Full Text Available The Young Masters Programme provides young people around the worldwith a net–based global–local learning environment for sustainable development. The present study investigates certain aspects of the implementation of this programme in the secondary schools of a Swedish municipality, in the context of the Lund Calling project. The research focuses on critical abilities to act globally, referred to as “knowledge capabilities”, and how they relate to the implementation process of initiating global learning for sustainabledevelopment (GLSD. A phenomenographic approach and semi–structuredinterviews were used in the investigation of the experiences of secondary school pupils, teachers and headmasters who participated in the project. Participants’ experiences of the changes carried out are described in relation to examples of knowledge capabilities needed for GLSD. Critical knowledge capabilities found to have been developed through the implementation were: to take command, and to collaborate. Critical knowledge capabilities perceived asnecessary, but not developed through the programme were: to be prepared, to act in a transdisciplinary manner, and to lead for a holistic understanding.

  18. Preparing Students for the Ethical Challenges of Global Citizenship

    Directory of Open Access Journals (Sweden)

    Madelyn Flammia

    2012-08-01

    Full Text Available This paper describes an approach to teaching ethical intercultural communication. This approach helps students become aware of their own ethnocentric attitudes and helps them move beyond those perspectives to develop a mindful approach to intercultural communication. The paper begins by introducing the concept of mindful communication and the challenges of developing of a code of ethical behavior for communicating across cultures. Then, strategies for reconciling cultural relativism and universalism are offered. Finally, the paper provides a set of guidelines for ethical behavior in intercultural encounters.

  19. Policy to support marine biotechnology-based solutions to global challenges.

    Science.gov (United States)

    Ritchie, Rachael J; Guy, Ken; Philp, Jim C

    2013-03-01

    Recent advances in science and technology are igniting new interest in marine biotechnology. Governments are recognizing the potential of marine biotechnology to provide solutions to grand global challenges of population health, food, and energy security and sustainable industry. This paper examines some of the challenges to and policy options for the development of marine biotechnology. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. The Challenges of Applying Planetary Boundaries as a Basis for Strategic Decision-Making in Companies with Global Supply Chains

    DEFF Research Database (Denmark)

    Clift, Roland; Sim, Sarah; King, Henry

    2017-01-01

    scales; second, the need to frame approaches to allocate fair shares in the 'safe operating space' bounded by the PBs across the value chain and; third, the need for international bodies to co-ordinate the implementation of the measures needed to respect the Planetary Boundaries. For the first two...... scales; (2) setting 'distance from boundary' measures that can be applied at different scales; (3) development of global, preferably open-source, databases and models; and (4) advancing understanding of the interactions between the different PBs. Addressing the scientific and technical challenges...

  1. Infopreneurs in service of rural enterprise and economic development: Addressing the critical challenges of scalability and sustainability in support of service extension in developing (rural) economies

    CSIR Research Space (South Africa)

    Van Rensburg, JR

    2010-08-31

    Full Text Available years’ work of ongoing research in a Living Lab fashion to understand and address the two critical challenges of scalability and sustainability in the utilisation of technology (primarily Information and Communication Technologies – ICTs) as enablers...

  2. The Century-Long Challenge of Global Carbon Management

    Science.gov (United States)

    Socolow, R.

    2002-05-01

    The time scale of the global carbon management is a century, not a decade and not a millennium. A century is the ratio of 1000 billion metric tons of carbon [Gt(C)] to 10 Gt(C)/yr. 1000 Gt(C) is the future emissions that will lead to approximately a doubling of the pre-industrial atmospheric CO2 concentration, 280 ppm, assuming the total net ocean plus terrestrial sink remains at half the strength of this source - since 2.1 Gt (C) = 1 ppm, and the concentration today is already 370 ppm. Doubling is the most widely used boundary between acceptable and unacceptable Greenhouse-related environmental disruption, or, in the language of the Framework Convention on Climate Change, the onset of "dangerous anthropogenic interference with the climate system." And 10 Gt(C)/yr is a conservative estimate of the average annual fossil-fuel carbon source over the century; it is now between 6 and 7 Gt(C). Conventional oil and gas are not sufficiently abundant to generate a serious Greenhouse problem on their own. Well before their cumulative carbon emissions reach 1000 Gt(C), both are expected to become non-competitive as a result of growing costs of access (costs related to resources being very deep underground, or below very deep water, or very remote, or very small.) But several times 1000 Gt(C) of coal resources will probably be competitive with non-fossil fuel alternatives, as will "unconventional" oil and gas resources, such as tar sands. The world will not be saved from a serious Greenhouse problem by fossil fuel depletion. There are four mitigation strategies for avoiding dangerous interference with the climate system. Fossil fuels can cease to dominate the global energy system well before the end of the century, yielding large market share to some combination of renewable energy and nuclear (fission and fusion) energy sources. Fossil fuels can continue to dominate, but most of the carbon in the century's fossil fuels can be prevented from reaching the atmosphere (fossil

  3. Apollo 2: Solar energy meets the new global challenge

    Energy Technology Data Exchange (ETDEWEB)

    Swenson, R. B [Santa Cruz, CA (United States)

    2000-07-01

    Humanity faces imminent and serious global oil shortages. It is urgent that the solar energy community respond aggressively to fulfill its central role in the transition from a transitory fossil-fuel economy to a sustainable solar future. The intention here is to explain and quantify the oil shortfall, to validate the renewable option, and to calculate the rate at which the capacity of the renewable energy industry must accelerate to counteract the predictable oil deficit. [Spanish] La humanidad se enfrenta a una seria e inminente escasez mundial de petroleo. Es urgente que la comunidad de energia solar responda agresivamente para satisfacer su rol central en la transicion de una economia transitoria de combustibles fosiles a un futuro solar sustentable. La intencion aqui es la de explicar y cuantificar el deficit de petroleo para validar esta opcion renovable y para calcular la velocidad a la que la industria de la energia renovable debe acelerar para contrarrestar el predecible deficit del petroleo.

  4. Globalization and loss of plant knowledge: challenging the paradigm.

    Directory of Open Access Journals (Sweden)

    Ina Vandebroek

    Full Text Available The erosion of cultural knowledge and traditions as a result of globalization and migration is a commonly reported phenomenon. We compared one type of cultural knowledge about medicinal plants (number of plants reported to treat thirty common health conditions among Dominican laypersons who self-medicate with plants and live in rural or urban areas of the Dominican Republic (DR, and those who have moved to New York City (NYC. Many plants used as medicines were popular Dominican food plants. These plants were reported significantly more often by Dominicans living in NYC as compared to the DR, and this knowledge was not age-dependent. These results contradict the popular paradigm about loss of cultural plant knowledge and is the first study to report a statistically measurable increase in this type of knowledge associated with migration.

  5. Media, cultural diversity and globalization: challenges and opportunities.

    Science.gov (United States)

    Zayani, Mohamed

    2011-01-01

    This paper explores the role media play in safeguarding cultural diversity, promoting cultural dialogue, facilitating the exercise of cultural rights,fostering cultural understanding and cultivating intercultural citizenship in the age of globalization. The paper highlights several interconnected leverage points: media content, practices, processes, ownership, education, structures, and policies. It argues that fostering cultural diversity in and through the media can go a long way toward bringing a civic discourse which favors tolerance and facilitates co-existence. It can contribute to the breaking down of cultural barriers, the initiation of cultural dialogues, the empowerment of marginalized groups, and the practice of good governance. At the same time, this paper argues, the celebration of difference does not preclude the valuation of a common cultural core or a common humanity which brings people together in spite of their differences.

  6. Globalization and Loss of Plant Knowledge: Challenging the Paradigm

    Science.gov (United States)

    Vandebroek, Ina; Balick, Michael J.

    2012-01-01

    The erosion of cultural knowledge and traditions as a result of globalization and migration is a commonly reported phenomenon. We compared one type of cultural knowledge about medicinal plants (number of plants reported to treat thirty common health conditions) among Dominican laypersons who self-medicate with plants and live in rural or urban areas of the Dominican Republic (DR), and those who have moved to New York City (NYC). Many plants used as medicines were popular Dominican food plants. These plants were reported significantly more often by Dominicans living in NYC as compared to the DR, and this knowledge was not age-dependent. These results contradict the popular paradigm about loss of cultural plant knowledge and is the first study to report a statistically measurable increase in this type of knowledge associated with migration. PMID:22662184

  7. The CharXive Challenge. Regulation of global carbon cycles by vegetation fires

    CERN Document Server

    Ball, R

    2010-01-01

    It is an open, but not unanswerable, question as to how much atmospheric CO2 is sequestered globally by vegetation fires. In this work I conceptualise the question in terms of the general CharXive Challenge, discuss a mechanism by which thermoconversion of biomass may regulate the global distribution of carbon between reservoirs, show how suppression of vegetation fires by human activities may increase the fraction of carbon in the atmospheric pool, and pose three specific CharXive Challenges of crucial strategic significance to our management of global carbon cycles.

  8. Energy policy: challenges of a global vision; Politique energetique: les enjeux d'une vision globale

    Energy Technology Data Exchange (ETDEWEB)

    Destot, Michel [ed.] [Depute de l' Isere, Assemblee Nationale, Paris (France)

    2000-02-18

    This is the proceedings of the 2. parliamentary gathering on energy held on 14 October 1999. The document presents the talks by Mr Michel Destot (as special rapporteur of the Industry's budget in National Assembly) and Laurent Fabius, President of National Assembly, and Jean-Claude Gayssot, Minister of Equipment, Transport and Dwelling, at the opening session, three round tables, the colloquium synthesis and the closing session. The round tables addressed the following issues: - 1. International and long-term approach guided predominantly by energy demand; - 2. Energy solutions in the struggle against greenhouse effect; - 3. Challenges of opening the European energy market (internationalization and decentralization). At the first round table, Yves Martin, President of the technical section of General Council of Mines, structured his introductory report emphasizing the specific issues of three time horizons: the present, characterized by abundant energy offer; the horizon of 10 to 20 years, that of the energy suppliers which is orienting their investments; the horizon of more than half a century, corresponding to responses of far-reaching actions imposed by energy demand and which must be the object of governments' policies. Jean-Yves Le Deaut, deputy of Meurthe-et-Moselle discussed the risks of climate change, resources' exhaustion, nuclear power and the issue of developing the renewable energies. The problems raised by energy demand by the year 2050 to met the needs of an earth population of 9 billions were mentioned by Philippe Trepant, the president of French Union of oil industries. Energy problems from a globalization standpoint were discussed also by Benjamin Dessus, Director of Ecodev program of CNRS. Policy in the field of mastering greenhouse gas releases was mentioned in the talk by Michel Mousel, president of Inter-ministerial Mission for greenhouse effect. In the frame of 2. round table questions relating to energy management, renewable

  9. Energy policy: challenges of a global vision; Politique energetique: les enjeux d'une vision globale

    Energy Technology Data Exchange (ETDEWEB)

    Destot, Michel [ed.] [Depute de l' Isere, Assemblee Nationale, Paris (France)

    2000-02-18

    This is the proceedings of the 2. parliamentary gathering on energy held on 14 October 1999. The document presents the talks by Mr Michel Destot (as special rapporteur of the Industry's budget in National Assembly) and Laurent Fabius, President of National Assembly, and Jean-Claude Gayssot, Minister of Equipment, Transport and Dwelling, at the opening session, three round tables, the colloquium synthesis and the closing session. The round tables addressed the following issues: - 1. International and long-term approach guided predominantly by energy demand; - 2. Energy solutions in the struggle against greenhouse effect; - 3. Challenges of opening the European energy market (internationalization and decentralization). At the first round table, Yves Martin, President of the technical section of General Council of Mines, structured his introductory report emphasizing the specific issues of three time horizons: the present, characterized by abundant energy offer; the horizon of 10 to 20 years, that of the energy suppliers which is orienting their investments; the horizon of more than half a century, corresponding to responses of far-reaching actions imposed by energy demand and which must be the object of governments' policies. Jean-Yves Le Deaut, deputy of Meurthe-et-Moselle discussed the risks of climate change, resources' exhaustion, nuclear power and the issue of developing the renewable energies. The problems raised by energy demand by the year 2050 to met the needs of an earth population of 9 billions were mentioned by Philippe Trepant, the president of French Union of oil industries. Energy problems from a globalization standpoint were discussed also by Benjamin Dessus, Director of Ecodev program of CNRS. Policy in the field of mastering greenhouse gas releases was mentioned in the talk by Michel Mousel, president of Inter-ministerial Mission for greenhouse effect. In the frame of 2. round table questions relating to energy management, renewable

  10. Challenge and Opportunity: the ALI/III Global Principles Project

    Directory of Open Access Journals (Sweden)

    IF Fletcher

    2008-04-01

    Full Text Available This article deals with an international project to establish the extent to which it is feasible to achieve a worldwide acceptance of the Principles of Cooperation among the NAFTA Countries together with the Guidelines Applicable to Court-to-Court Communications in Cross-Border Cases. This contribution explains the process whereby the American Law Institute and the International Insolvency Institute (1 developed principles of cooperation with regard to cross-border insolvency; (2 established acceptance of these principles in jurisdictions across the world, subject to any necessary local modifications; and (3 obtained the endorsement of leading domestic associations, courts, and other groups in those jurisdictions. This article may contribute to the development the South African cross-border insolvency law. The inclusion of the challenges of harmonisation of private international law is also contributing to current debate.

  11. Diagnosing turnover times of carbon in terrestrial ecosystems to address global climate co-variability and for model evaluation

    Science.gov (United States)

    Carvalhais, Nuno; Thurner, Martin; Forkel, Matthias; Beer, Christian; Reichstein, Markus

    2016-04-01

    The response of the global terrestrial carbon cycle to climate change and the associated climate-carbon feedback has been shown to be highly uncertain. Ultimately this response depends on how carbon assimilation by vegetation changes relatively to the effective mean turnover time of carbon in vegetation and soils. Consequently, these turnover times of carbon are expected to depend on vegetation longevity and relative allocation to woody and non-woody biomass, and to litter and soil organic matter decomposition rates, which depend on climate variables, but also soil properties, biological activity and chemical composition of the litter. Data oriented estimates of whole ecosystem carbon turnover rates (τ) are based on global datasets of carbon stocks and fluxes and used to diagnose the co-variability of τ with climate. The overall mean global carbon turnover time estimated is 23 years (with 95% confidence intervals between 19 and 30 years), showing a strong spatial variability ranging from 15 years in equatorial regions to 255 years at latitudes north of 75°N. This latitudinal pattern reflects the expected dependencies of metabolic activity and ecosystem dynamics to temperature. However, a strong local correlation of τ with mean annual precipitation patterns is at least as prevalent as the expected effect of temperature on the global patterns of τ. The comparing between observation-based estimates of τ with current state-of-the-art Earth system models shows a consistent latitudinal pattern but a significant underestimation bias of ˜36% globally. Models consistently show a stronger association of τ to temperature and do not reproduce the observed association to mean annual precipitation in different latitudinal bands. A further breakdown of τ focusing on forest background mortality also shows contrasting regional patterns to those of global vegetation models, suggesting that the treatment of plant mortality may be overly simplistic in different model

  12. Injuries and violence: a global public health challenge

    Directory of Open Access Journals (Sweden)

    Muazzam Nasrullah

    2010-06-01

    Full Text Available Injuries and violence are a significant cause of mortality and physical disability. Injuries killed five million people worldwide each year [1]. The level of this dilemma, however, differs significantly by age, sex, region and economic development [2]. Globally, road traffic injury mortalities, self-inflicted injury mortality and interpersonal violence, war, drowning, and exposure to fire are the leading cause of deaths among people aged 15-44 years [3]. This special issue aims to assess the magnitude of this problem, identify risk factors and explore prevention strategies to alleviate the burden of injuries and violence. There is a dire need to increase the knowledge of the extent of problem, and associated risk factors that needs to be targeted for prevention. Erosa et al., examined reports of verbal and physical abuse from family caregivers of adults with severe physical, neurological and developmental disabilities, and found that caregivers who reported some form of abuse reported significantly greater distress and burden than caregivers who did not report any abuse. Grice et al., found that reported histories of work-related physical assault and work-related threat were associated with elevated risks of current work-related physical assault. Ahmad, systematically reviewed and summarized current scientific knowledge on the use of interactive computer-assisted screening to detect intimate partner violence (IPV.

  13. University economists training under global educational environment: challenges and prospects

    Directory of Open Access Journals (Sweden)

    Bagautdinova Nailya G.

    2016-01-01

    Full Text Available Kazan Federal University being the leading one in the Volga region has set a strategic goal of academic reputation and University authority growth to achieve a high level of international recognition. The article describes the measures that were implemented by University management to enter the list of world leading universities. Some tools that accompany and foster necessary transformation are described and the way to align strategic priorities and economists training programs development is analyzed. The paper considers Bachelor and Master Degree courses in Economics and Management reshaping and establishes connection between New Third Generation Educational Standard introduction into the system of higher education and the process of University integration into the global educational environment. The new competence-based paradigm and interdisciplinary approach are both considered as important steps to improve academic and research performance. The “road map” developed and implemented by University management team was used as a platform for content analysis of qualitative data via systematic examination and verification of projected indicators open for public consideration on the official University web-page.

  14. Global warming presents new challenges for maize pest management

    Science.gov (United States)

    Diffenbaugh, Noah S.; Krupke, Christian H.; White, Michael A.; Alexander, Corinne E.

    2008-10-01

    It has been conjectured that global warming will increase the prevalence of insect pests in many agro-ecosystems. In this paper, we quantitatively assess four of the key pests of maize, one of the most important systems in North American grain production. Using empirically generated estimates of pest overwintering thresholds and degree-day requirements, along with climate change projections from a high-resolution climate model, we project potential future ranges for each of these pests in the United States. Our analysis suggests the possibility of increased winter survival and greater degree-day accumulations for each of the pests surveyed. We find that relaxed cold limitation could expand the range of all four pest taxa, including a substantial range expansion in the case of corn earworm (H. zea), a migratory, cold-intolerant pest. Because the corn earworm is a cosmopolitan pest that has shown resistance to insecticides, our results suggest that this expansion could also threaten other crops, including those in high-value areas of the western United States. Because managing significant additional pressure from this suite of established pests would require additional pest management inputs, the projected decreases in cold limitation and increases in heat accumulation have the potential to significantly alter the pest management landscape for North American maize production. Further, these range expansions could have substantial economic impacts through increased seed and insecticide costs, decreased yields, and the downstream effects of changes in crop yield variability.

  15. New global top-level domain names: Europe, the challenger

    Directory of Open Access Journals (Sweden)

    Francesca Musiani

    2013-06-01

    Full Text Available New generic top-level domain names (gTLDs are the highest level of domain names in the domain name system (DNS; their number has been restricted to twenty-two for several years, and ICANN has implemented restrictions on the ways in which they are operated. The new gTLD programme, proposed by the Internet Corporation for Assigned Names and Numbers (ICANN in early 2013, enables businesses and organisations to apply for their own customised top-level domain names, thereby greatly expanding their current number. ICANN’s move is the most recent controversial one in a subfield of DNS management and internet governance, already rife with political and economic controversies. What are the implications of this 'turn' to new gTLDs? This article attempts to outline them, and addresses the impact of the new gTLDs programme on Europe’s action-taking in the internet governance realm. The article also considers the likely impact of the new programme on ICANN’s governance and weight vis-à-vis other important internet governance actors.

  16. Implementing ERP Systems Globally: Challenges and Lessons Learned for Asian Countries

    Directory of Open Access Journals (Sweden)

    Paul Hawking

    2014-09-01

    Full Text Available Improved communication technology has seen growth in a convergence of global corporate activities. In an effort to improve their global operations many companies are implementing global information systems in particular Enterprise Resource Planning (ERP systems. Companies are faced with a number of complexities when implementing these systems in a single country and considerable research has been conducted on the critical success factors associated with ERP implementations. However very little research has been conducted on the issues associated with global implementations of ERP systems and in particular implementations within the Asian region. This research utilises industry presentations to identify challenges and best practice for global implementations from the Asian region. The challenges have been classified as either technological or cultural pertaining to particular countries. The identified factors provide a foundation for further investigation.

  17. NKS - The Nordic region's cooperative network for addressing challenges in nuclear safety and emergency preparedness

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, K.G. [NKS/Technical University of Denmark (Denmark); Andgren, K. [NKS/Vattenfall R and D (Sweden); Leino, K. [NKS/Fortum Power and Heat Oy (Finland); Magnusson, S. [NKS/Icelandic Radiation Safety Authority (Iceland); Physant, F. [NKS/FRIT, Roskilde (Denmark)

    2014-07-01

    Based on the foundation of a common cultural and historical heritage and a long tradition of collaboration, NKS aims to facilitate a common Nordic view on nuclear and radiation safety. A common understanding of rules, practice and measures, and national differences in this context, is here an essential requirement. Problems can generally be tackled quicker, more efficiently, more consistently and at a lower cost through collaboration, bearing in mind that key competencies are not equally distributed in the different Nordic countries. For instance common Nordic challenges emerge in relation to nuclear installations, where nuclear power plants are in operation in Finland and Sweden, and research reactors have been operated in Denmark, Finland, Norway and Sweden. There is an obvious benefit in exchanging ideas and technologies in relation to plant operation, and since a number of reactors in different Nordic countries are under decommissioning, a collaborative benefit can also be realised in that context. Sweden also has a nuclear fuel production plant, and its collaboration with other Nordic nuclear installations can also be beneficial. Further, a number of large radiological installations are projected in Nordic areas (e.g., the MAX-LAB/MAX IV synchrotron radiation source and the European spallation source ESS), where Nordic organisations are collaborating in addressing, e.g., potential environmental implications. On the emergency preparedness side, the Fukushima accident in March 2011 was a reminder that large accidents at nuclear installations can lead to widespread radioactive contamination in the environment. In order to respond to nuclear or radiological emergencies, should they affect Nordic populations, it is necessary to maintain an operational emergency preparedness. By continuously improving detection, response and decision aiding tools while maintaining an informal collaborative network between relevant stakeholders in the Nordic countries (including

  18. Localizing the Global and Globalizing the Local: Opportunities and Challenges in Bali Island Tourism Development

    OpenAIRE

    I Nyoman Darma Putra

    2015-01-01

    AbstractIn September and October 2013, only one week apart,Bali hosted two global events in the upper class markettourism resort Nusa Dua. The first event was the MissWorld beauty pageant, and the other one was the APECSummit. Thousands of journalists from all over the worldcovered these events. From a tourism marketing point ofview, these two prestigious events helped Bali boost itspopularity through global mass media. Historically, sincethe early phase of its development, Bali’s tourism ind...

  19. In silico regenerative medicine: how computational tools allow regulatory and financial challenges to be addressed in a volatile market.

    Science.gov (United States)

    Geris, L; Guyot, Y; Schrooten, J; Papantoniou, I

    2016-04-06

    The cell therapy market is a highly volatile one, due to the use of disruptive technologies, the current economic situation and the small size of the market. In such a market, companies as well as academic research institutes are in need of tools to advance their understanding and, at the same time, reduce their R&D costs, increase product quality and productivity, and reduce the time to market. An additional difficulty is the regulatory path that needs to be followed, which is challenging in the case of cell-based therapeutic products and should rely on the implementation of quality by design (QbD) principles. In silico modelling is a tool that allows the above-mentioned challenges to be addressed in the field of regenerative medicine. This review discusses such in silico models and focuses more specifically on the bioprocess. Three (clusters of) examples related to this subject are discussed. The first example comes from the pharmaceutical engineering field where QbD principles and their implementation through the use of in silico models are both a regulatory and economic necessity. The second example is related to the production of red blood cells. The described in silico model is mainly used to investigate the manufacturing process of the cell-therapeutic product, and pays special attention to the economic viability of the process. Finally, we describe the set-up of a model capturing essential events in the development of a tissue-engineered combination product in the context of bone tissue engineering. For each of the examples, a short introduction to some economic aspects is given, followed by a description of the in silico tool or tools that have been developed to allow the implementation of QbD principles and optimal design.

  20. Technical challenges in designing post-marketing eCRFs to address clinical safety and pharmacovigilance needs.

    Science.gov (United States)

    Lu, Zhengwu

    2010-01-01

    To identify key challenges and propose technical considerations in designing electronic case report form (eCRF) for post-marketing studies, the author undertakes a comprehensive literature review of peer reviewed and grey literature to assess the key aspects, processes, standards, recommendations, and best practices in designing eCRFs based on industry experience in designing and supporting electronic data capture (EDC) studies. Literature search using strings on MEDLINE and PUBMED returned few papers directly related to CRF design. Health informatics and general practice journals were searched and results reviewed. Many conference, government commission, health professional and special interests group websites provide relevant information from practical experience - summarization of this information is presented. Further, we presented a list of concrete technical considerations in dealing with EDC technology/system limitations based on literature assessment and industry implementation experience. It is recognized that cross-functional teams be involved in eCRF design process and decision making. To summarize the keys in designing eCRFs to address post-market study safety and pharmacovigilance needs, the first is to identify required data elements from the study protocol supporting data analyses and reporting requirements. Secondly, accepted best practices, CDASH & CDISC guidelines, and company internal or therapeutic unit standard should be considered and applied. Coding (MedDRA & WHODD) mapping should be managed and implemented as well when possible. Finally, we need to be on top of the EDC technologies, challenge the technologies, drive EDC improvement via working with vendors, and utilize the technologies to drive clinical effectiveness. Copyright (c) 2009 Elsevier Inc. All rights reserved.

  1. Big Data challenges and solutions in building the Global Earth Observation System of Systems (GEOSS)

    Science.gov (United States)

    Mazzetti, Paolo; Nativi, Stefano; Santoro, Mattia; Boldrini, Enrico

    2014-05-01

    The Group on Earth Observation (GEO) is a voluntary partnership of governments and international organizations launched in response to calls for action by the 2002 World Summit on Sustainable Development and by the G8 (Group of Eight) leading industrialized countries. These high-level meetings recognized that international collaboration is essential for exploiting the growing potential of Earth observations to support decision making in an increasingly complex and environmentally stressed world. To this aim is constructing the Global Earth Observation System of Systems (GEOSS) on the basis of a 10-Year Implementation Plan for the period 2005 to 2015 when it will become operational. As a large-scale integrated system handling large datasets as those provided by Earth Observation, GEOSS needs to face several challenges related to big data handling and big data infrastructures management. Referring to the traditional multiple Vs characteristics of Big Data (volume, variety, velocity, veracity and visualization) it is evident how most of them can be found in data handled by GEOSS. In particular, concerning Volume, Earth Observation already generates a large amount of data which can be estimated in the range of Petabytes (1015 bytes), with Exabytes (1018) already targeted. Moreover, the challenge is related not only to the data size, but also to the large amount of datasets (not necessarily having a big size) that systems need to manage. Variety is the other main challenge since datasets coming from different sensors, processed for different use-cases are published with highly heterogeneous metadata and data models, through different service interfaces. Innovative multidisciplinary applications need to access and use those datasets in a harmonized way. Moreover Earth Observation data are growing in size and variety at an exceptionally fast rate and new technologies and applications, including crowdsourcing, will even increase data volume and variety in the next future

  2. Tara Oceans' approach and new challenges in studying the ocean microbiome at global scale

    Science.gov (United States)

    Coelho, L. P.; Sunagawa, S.; Chaffron, S.; Bowler, C.; Winker, P.; Karsenti, E.; Raes, J.; Acinas, S. G.; Bork, P.

    2016-02-01

    Drawing an ecosystem-wide picture of community structure, functional diversity and ecological drivers of the ocean microbiome has been a grand challenge. This has been primarily due to the lack of a systematically collected set of samples with associated environmental information at global scale. To address this limitation, Tara Oceans has so far collected more than 35,000 samples for genomic, morphological and environmental analyses from all major oceanic regions. Using an eco-systems biology approach, we analyzed 7.2 terabases of metagenomic data from 243 water samples that were collected at multiple depths to determine the main stratifying factors and environmental drivers of ocean microbial community structure and function. To this end, we constructed and annotated an ocean microbial reference gene catalog with >40 million non-redundant, mostly novel sequences from viruses, prokaryotes and picoeukaryotes. A focus on 139 prokaryote-enriched samples revealed microbiota to be primarily stratified into epipelagic and mesopelagic communities. For epipelagic communities, we disentangled co-correlations of environmental parameters and identified microbial communities composition to be mainly driven by temperature rather than geography. To resolve this overall pattern from community to species-level, we reconstructed clusters of core genes of dominant ocean microbial species and investigate their biogeography based on metagenomic profiling of single nucleotide polymorphisms. The integration of metatranscriptomic data is adding an additional layer of information to study their activity as a function of physicochemical differences of their environment.

  3. Training Solutions to the Global Challenges of a Nuclear Renaissance

    Energy Technology Data Exchange (ETDEWEB)

    Garces, M.; Chan, S.; Leo, C.; Garcia, S.; Vidal, B.

    2010-07-01

    From East Asia to the United States and all over Europe, the nuclear re-birth is generating demands the training simulation vendors had not faced before. Companies involved in the planning, design, construction and operation of new plants increasingly require simulation tools to satisfy very different needs, all of them on a large scale: education and support of inexperienced newcomer staff, human factors analysis and control room design, e-learning, verification and validation of I and C systems or training and licensing of crews before the actual installations are complete. There is a full set of applications already available to the whole industry to satisfy these needs. End-user friendly Thunder Real-Time Executive (T-REX), poised to become the standard simulation platform for U.S. plants, makes it possible to provide full-scope simulator and simulator exercises to students and others on a memory stick or over the internet. AREVA EPR full-scope training simulator, based on the ALICES integrated object-oriented simulation environment, becomes an engineering simulator for the Flamanville 3 plant under construction in Normandy; the same will happen to the Taishan 1 and 2 simulators in Guangdong (China) while UniStar plans to apply this approach to the future EPR's to be built in the United States. SIREP PWR Basic Principle Simulator, with simplified models which can run on an ordinary PC, is used at GDF SUEZ offices in Brussels to implement their Nuclear Trainees Program. EDF Training Department chooses On-line Micro Simulation (MicroSel), which can be managed with Learning Management Systems, for classroom and stand-alone learning of the basic characteristics of French reactors. All these are examples of how extensive R and D and innovation programs implemented by the simulator providers, some of them under way here in Spain, will help to overcome some of the challenges of the current nuclear expansion.

  4. Global challenges for e-waste management: the societal implications.

    Science.gov (United States)

    Magalini, Federico

    2016-03-01

    Over the last decades the electronics industry and ICT Industry in particular has revolutionized the world: electrical and electronic products have become ubiquitous in today's life around the planet. After use, those products are discarded, sometimes after re-use cycles in countries different from those where they were initially sold; becoming what is commonly called e-waste. Compared to other traditional waste streams, e-waste handling poses unique and complex challenges. e-Waste is usually regarded as a waste problem, which can cause environmental damage and severe human health consequences if not safely managed. e-Waste contains significant amounts of toxic and environmentally sensitive materials and is, thus, extremely hazardous to humans and the environment if not properly disposed of or recycled. On the other hand, e-waste is often seen as a potential source of income for individuals and entrepreneurs who aim to recover the valuable materials (metals in particular) contained in discarded equipment. Recently, for a growing number of people, in developing countries in particular, recycling and separation of e-waste has become their main source of income. In most cases, this is done informally, with no or hardly any health and safety standards, exposing workers and the surrounding neighborhoods to extensive health dangers as well as leading to substantial environmental pollution. Treatment processes of e-waste aim to remove the hazardous components and recover as much reusable material (e.g. metals, glass and plastics) as possible; achieving both objectives is most desired. The paper discuss societal implications of proper e-waste management and key elements to be considered in the policy design at country level.

  5. Big Data Science: Opportunities and Challenges to Address Minority Health and Health Disparities in the 21st Century.

    Science.gov (United States)

    Zhang, Xinzhi; Pérez-Stable, Eliseo J; Bourne, Philip E; Peprah, Emmanuel; Duru, O Kenrik; Breen, Nancy; Berrigan, David; Wood, Fred; Jackson, James S; Wong, David W S; Denny, Joshua

    2017-01-01

    Addressing minority health and health disparities has been a missing piece of the puzzle in Big Data science. This article focuses on three priority opportunities that Big Data science may offer to the reduction of health and health care disparities. One opportunity is to incorporate standardized information on demographic and social determinants in electronic health records in order to target ways to improve quality of care for the most disadvantaged populations over time. A second opportunity is to enhance public health surveillance by linking geographical variables and social determinants of health for geographically defined populations to clinical data and health outcomes. Third and most importantly, Big Data science may lead to a better understanding of the etiology of health disparities and understanding of minority health in order to guide intervention development. However, the promise of Big Data needs to be considered in light of significant challenges that threaten to widen health disparities. Care must be taken to incorporate diverse populations to realize the potential benefits. Specific recommendations include investing in data collection on small sample populations, building a diverse workforce pipeline for data science, actively seeking to reduce digital divides, developing novel ways to assure digital data privacy for small populations, and promoting widespread data sharing to benefit under-resourced minority-serving institutions and minority researchers. With deliberate efforts, Big Data presents a dramatic opportunity for reducing health disparities but without active engagement, it risks further widening them.

  6. Addressing Challenges to Enhance the Bioactives of Withania somnifera through Organ, Tissue, and Cell Culture Based Approaches

    Science.gov (United States)

    Singh, Pritika; Guleri, Rupam; Angurala, Amrita; Kaur, Kuldeep; Kaur, Kulwinder; Kaul, Sunil C.; Wadhwa, Renu

    2017-01-01

    Withania somnifera is a highly valued medicinal plant in traditional home medicine and is known for a wide range of bioactivities. Its commercial cultivation is adversely affected by poor seed viability and germination. Infestation by various pests and pathogens, survival under unfavourable environmental conditions, narrow genetic base, and meager information regarding biosynthesis of secondary metabolites are some of the other existing challenges in the crop. Biotechnological interventions through organ, tissue, and cell culture provide promising options for addressing some of these issues. In vitro propagation facilitates conservation and sustainable utilization of the existing germplasms and broadening the genetic base. It would also provide means for efficient and rapid mass propagation of elite chemotypes and generating uniform plant material round the year for experimentation and industrial applications. The potential of in vitro cell/organ cultures for the production of therapeutically valuable compounds and their large-scale production in bioreactors has received significant attention in recent years. In vitro culture system further provides distinct advantage for studying various cellular and molecular processes leading to secondary metabolite accumulation and their regulation. Engineering plants through genetic transformation and development of hairy root culture system are powerful strategies for modulation of secondary metabolites. The present review highlights the developments and sketches current scenario in this field.

  7. Global Social Challenges: insights from the physical sciences and their relevance to the evolution of social science

    CERN Document Server

    CERN. Geneva

    2014-01-01

    The complex challenges confronting humanity today point to the need for new thinking and new theory in the social sciences which overcomes the limitations of compartmentalized, sectoral concepts, strategies and policies and mechanistic approaches to living social systems. The World Academy of Art & Science is convening a consortium of leading institutions and thinkers from different sectors to contribute ideas for formulation of a cohesive framework capable of addressing global social challenges in their totality and complex interrelationships. The objective of my presentation will be to explore the potential for collaboration between the physical and social sciences to arrive at a more cohesive and effective framework by exploring a series of questions, including - - Is an integrated science of society possible that transcends disciplinary boundaries based on common underlying principles as we find in the natural sciences? - To what extent can principles of natural science serve as valid models and a...

  8. The Human Resources Challenge to Community Based Rehabilitation: The Need for a Scientific, Systematic and Coordinated Global Response

    Directory of Open Access Journals (Sweden)

    Eilish McAuliffe

    2013-02-01

    Full Text Available The World Report on Disability highlights some of the major challenges in the path to realisation of the rights of persons with disabilities as per the United Nations Convention. While the recently published guidelines on Community Based Rehabilitation show the way to address these challenges, effective implementation would require not only higher levels of investment in human resources, but also a significantly newer and different skill-set for the additional personnel.  The authors suggest that a scientifically sophisticated, systematic and coordinated research programme, with global reach and participation, is needed for the establishment of a useful and robust evidence-base for Community Based Rehabilitation interventions. It is also suggested that the development of a new cadre of rehabilitation workers could be a key component of the programme, and could help to alleviate the extant crisis in human resources for health in many low-income countries.

  9. Northern Eurasia Future Initiative: Facing the Challenges of Global Change in the 21st century

    Science.gov (United States)

    Groisman, Pavel; Gutman, Garik; Gulev, Sergey; Maksyutov, Shamil; Qi, Jiaguo

    2016-04-01

    During the past 12 years, the Northern Eurasia Earth Science Partnership Initiative (NEESPI) - an interdisciplinary program of internationally-supported Earth systems and science research - has addressed large-scale and long-term manifestations of climate and environmental changes over Northern Eurasia and their impact on the Global Earth system. With more than 1500 peer-reviewed journal publications and 40 books to its credit, NEESPI's activities resulted in significant scientific outreach. This created a new research realm through self-organization of NEESPI scientists in a broad research network, accumulation of knowledge while developing new tools (observations, models, and collaborative networks) and producing new, exciting results that can be applied to directly support decision-making for societal needs. This realm was summed up at the Synthesis NEESPI Workshop in Prague, Czech Republic (April 9-12, 2015) where it was decided to shift gradually the foci of regional studies in Northern Eurasia towards applications with the following major Science Question: " What dynamic and interactive change(s) will affect societal well-being, activities, and health, and what might be the mitigation and adaptation strategies that could support sustainable development and decision-making activities in Northern Eurasia?". To answer this question requires a stronger socio-economic component in the ongoing and future regional studies focused on sustainable societal development under changing climatic and environmental conditions, especially, under conditions when societal decision-making impacts and feeds back on the environment. This made the NEESPI studies closer to the ICSU research initiative "Future Earth". Accordingly, the NEESPI Research Team decided to reorganize in the nearest future NEESPI into "Northern Eurasia Future Initiative" (NEFI) and began development of its Programmatic White Paper (in preparation at the time of this abstract submission). The NEFI research

  10. Performance-based incentives may be appropriate to address challenges to delivery of prevention of vertical transmission of HIV services in rural Mozambique: a qualitative investigation.

    Science.gov (United States)

    Schuster, Roseanne C; de Sousa, Octávio; Rivera, Jacqueline; Olson, Rebecca; Pinault, Delphine; Young, Sera L

    2016-10-07

    Performance-based incentives (PBIs) have garnered global attention as a promising strategy to improve healthcare delivery to vulnerable populations. However, literature gaps in the context in which an intervention is implemented and how the PBIs were developed exist. Therefore, we (1) characterized the barriers and promoters to prevention of vertical transmission of HIV (PVT) service delivery in rural Mozambique, where the vertical transmission rate is 12 %, and (2) assessed the appropriateness for a PBI's intervention and application to PVT. We conducted 24 semi-structured interviews with nurses, volunteers, community health workers, and traditional birth attendants about the barriers and promoters they experienced delivering PVT services. We then explored emergent themes in subsequent focus group discussions (n = 7, total participants N = 92) and elicited participant perspectives on PBIs. The ecological motivation-opportunity-ability framework guided our iterative data collection and thematic analysis processes. The interviews revealed that while all health worker cadres were motivated intrinsically and by social recognition, they were dissatisfied with low and late remuneration. Facility-based staff were challenged by factors across the rest of the ecological levels, primarily in the opportunity domain, including the following: poor referral and record systems (work mandate), high workload, stock-outs, poor infrastructure (facility environment), and delays in obtaining patient results and donor payment discrepancies (administrative). Community-based cadres' opportunity challenges included lack of supplies, distance (work environment), lack of incorporation into the health system (administration), and ability challenges of incorrect knowledge (health worker). PBIs based on social recognition and that enable action on intrinsic motivation through training, supervision, and collaboration were thought to have the most potential for targeting improvements

  11. The impact of climate change on the global wine industry: Challenges & solutions

    Directory of Open Access Journals (Sweden)

    Michelle Renée Mozell

    2014-12-01

    Full Text Available This paper explores the impact of climate change upon the global production of winegrapes and wine. It includes a review of the literature on the cause and effects of climate change, as well as illustrations of the specific challenges global warming may bring to the production of winegrapes and wine. More importantly, this paper provides some practical solutions that industry professionals can take to mitigate and adapt to the coming change in both vineyards and wineries.

  12. Using Technology to Prepare Students for the Challenges of Global Citizenship

    Directory of Open Access Journals (Sweden)

    Houman Sadri

    2009-10-01

    Full Text Available In the modern world, everyone must recognize that it is nearly impossible to separate many domestic and international problems and managing international challenges will take the efforts of all nations. As a result, each and every person must think like a global citizen and practice mindfulness in daily life. Using the complex interdependence model as a basis for examining citizen diplomacy, this paper suggests ways that new media can be used to introduce students to a global perspective on the world. Further, it provides faculty members with a set of guidelines for structuring projects that task students with the challenge of taking positive action to effect political and societal change.

  13. Improving patient safety in transfusion medicine: contemporary challenges and the roles for bedside and laboratory biovigilance in addressing them

    Directory of Open Access Journals (Sweden)

    Andrzejewski Jr C

    2014-07-01

    Full Text Available Chester Andrzejewski Jr,1 Darlene Cloutier,1 David Unold,2 Richard C Friedberg1 1Transfusion Medicine Services, Department of Pathology, Baystate Medical Center, Baystate Health, Springfield, MA, 2Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT, USA Abstract: Throughout the history of hemotherapy (HT, various challenges and concerns have been encountered in its practical application. When viewed using a prismatic lens of history, recurrent themes regarding adverse HT sequelae separate and become apparent. These can be broadly classified into three categories: infectious, noninfectious, and administrative/logistical. Using the HT care map as a frame of reference along with its associated rites, we examine the contemporary spectrum of HT adverse events and concerns, and some approaches as to how these may be addressed from bedside and laboratory medicine biovigilance perspectives enhancing patient care and blood transfusion safety. Although our vantage point is from an academic community hospital venue, the issues and concerns identified are germane to many if not all transfusion-medicine practice environments. Included among the subjects we explore are patient/specimen identification issues, blood-management initiatives, unrecognized and/or unreported suspected transfusion reactions, transfusion-associated adverse pulmonary sequelae (including transfusion-related acute lung injury and transfusion-associated circulatory overload, expanded applications of electronic health records and issues regarding their “meaningful use” and interinstitutional “digital compatibilities”, biovigilance integration of electronic data networks within and between health care entities, and anticipated workforce contractions secondary to projected declines in the availability of qualified laboratory professionals. Cooperative initiatives between accreditation and regulatory entities, blood collectors and suppliers, hospital

  14. Addressing the challenges of using ferromagnetic electrodes in the magnetic tunnel junction-based molecular spintronics devices

    Science.gov (United States)

    Tyagi, Pawan; Friebe, Edward; Baker, Collin

    2015-11-01

    Addressing the challenges of using high-Curie temperature ferromagnetic (FM) electrodes is critical for molecular spintronics devices (MSDs) research. Two FM electrodes simultaneously chemically bonded with a thiol-functionalized molecule can produce novel MSDs to exploring new quantum mechanical phenomenon and computer technologies. For developing a commercially viable MSD, it is crucial to developing a device fabrication scheme that carefully considers FM electrodes' susceptibility to oxidation, chemical etching, and stress-induced deformations during fabrication and usage. This paper studies NiFe, an alloy extensively used in present-day memory devices and high-temperature engineering applications, as a candidate FM electrode for the fabrication of MSDs. Our spectroscopic reflectance studies show that NiFe oxidized aggressively after heating beyond 90 °C. The NiFe surfaces, aged for several months or heated for several minutes below 90 °C, exhibited remarkable electrochemical activity and were found suitable for chemical bonding with the thiol-functionalized molecular device elements. NiFe also demonstrated excellent etching resistance against commonly used solvents and lithography related chemicals. Additionally, NiFe mitigated the adverse effects of mechanical stress by subsiding the stress-induced deformities. A magnetic tunnel junction-based MSD approach was designed by carefully considering the merits and limitations of NiFe. The device fabrication protocol considers the safe temperature limit to avoiding irreversible surface oxidation, the effect of mechanical stresses, surface roughness, and chemical etching. This paper provides foundational experimental insights in realizing a versatile MSD allowing a wide range of transport and magnetic studies.

  15. Addressing the challenges of using ferromagnetic electrodes in the magnetic tunnel junction-based molecular spintronics devices

    Energy Technology Data Exchange (ETDEWEB)

    Tyagi, Pawan, E-mail: ptyagi@udc.edu; Friebe, Edward; Baker, Collin [University of the District of Columbia, Department of Mechanical Engineering (United States)

    2015-11-15

    Addressing the challenges of using high-Curie temperature ferromagnetic (FM) electrodes is critical for molecular spintronics devices (MSDs) research. Two FM electrodes simultaneously chemically bonded with a thiol-functionalized molecule can produce novel MSDs to exploring new quantum mechanical phenomenon and computer technologies. For developing a commercially viable MSD, it is crucial to developing a device fabrication scheme that carefully considers FM electrodes’ susceptibility to oxidation, chemical etching, and stress-induced deformations during fabrication and usage. This paper studies NiFe, an alloy extensively used in present-day memory devices and high-temperature engineering applications, as a candidate FM electrode for the fabrication of MSDs. Our spectroscopic reflectance studies show that NiFe oxidized aggressively after heating beyond ∼90 °C. The NiFe surfaces, aged for several months or heated for several minutes below ∼90 °C, exhibited remarkable electrochemical activity and were found suitable for chemical bonding with the thiol-functionalized molecular device elements. NiFe also demonstrated excellent etching resistance against commonly used solvents and lithography related chemicals. Additionally, NiFe mitigated the adverse effects of mechanical stress by subsiding the stress-induced deformities. A magnetic tunnel junction-based MSD approach was designed by carefully considering the merits and limitations of NiFe. The device fabrication protocol considers the safe temperature limit to avoiding irreversible surface oxidation, the effect of mechanical stresses, surface roughness, and chemical etching. This paper provides foundational experimental insights in realizing a versatile MSD allowing a wide range of transport and magnetic studies.

  16. How the Social-Ecological Systems Concept Can Guide Transdisciplinary Research and Implementation: Addressing Water Challenges in Central Northern Namibia

    Directory of Open Access Journals (Sweden)

    Stefan Liehr

    2017-06-01

    Full Text Available Research aimed at contributing to the further development of integrated water resources management needs to tackle complex challenges at the interface of nature and society. A case study in the Cuvelai-Etosha Basin in Namibia has shown how semi-arid conditions coinciding with high population density and urbanisation present a risk to people’s livelihoods and ecosystem health. In order to increase water security and promote sustainable water management, there is a requirement for problem-oriented research approaches combined with a new way of thinking about water in order to generate evidence-based, adapted solutions. Transdisciplinary research in particular addresses this issue by focusing on the problems that arise when society interacts with nature. This article presents the implementation of a transdisciplinary research approach in the above-mentioned case study. The concept of social-ecological systems (SES plays a key role in operationalising the transdisciplinary research process. Application of the SES concept helps to outline the problem by defining the epistemic object, as well as structure the research process itself in terms of formulating research questions and developing the research design. It is argued here that the SES concept is not merely useful, but also necessary for guiding transdisciplinary sustainability research and implementation. The study from Namibia clearly demonstrates that the introduction of technological innovations such as rainwater and floodwater harvesting plants requires a social-ecological perspective. In particular this means considering questions around knowledge, practices and institutions related to water resources management and includes various societal innovations alongside technologies on the agenda.

  17. Facing the Future: Time for the EU to meet Global Challenges

    OpenAIRE

    BODEN John Mark; CAGNIN CRISTIANO; CARABIAS BARCELO VICENTE; HAEGEMAN Karel; KÖNNÖLÄ Timo-Topias Totti

    2010-01-01

    What will the world look like in 2025? What are the possible future disruptive global challenges? And how can the EU position itself to take an active role in shaping a response to them? This publication offers possible answers to these questions through the identification of three main challenges and potential responses to these, and concludes that the main policy issues to be considered at EU level are: policy alignment towards sustainability; social diversity and the use of ICT for citizen...

  18. Global plagues and the Global Fund: Challenges in the fight against HIV, TB and malaria

    Directory of Open Access Journals (Sweden)

    Tan Darrell HS

    2003-04-01

    Full Text Available Abstract Background Although a grossly disproportionate burden of disease from HIV/AIDS, TB and malaria remains in the Global South, these infectious diseases have finally risen to the top of the international agenda in recent years. Ideal strategies for combating these diseases must balance the advantages and disadvantages of 'vertical' disease control programs and 'horizontal' capacity-building approaches. Discussion The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM represents an important step forward in the struggle against these pathogens. While its goals are laudable, significant barriers persist. Most significant is the pitiful lack of funds committed by world governments, particularly those of the very G8 countries whose discussions gave rise to the Fund. A drastic scaling up of resources is the first clear requirement for the GFATM to live up to the international community's lofty intentions. A directly related issue is that of maintaining a strong commitment to the treatment of the three diseases along with traditional prevention approaches, with the ensuing debates over providing affordable access to medications in the face of the pharmaceutical industry's vigorous protection of patent rights. Summary At this early point in the Fund's history, it remains to be seen how these issues will be resolved at the programming level. Nevertheless, it is clear that significant structural changes are required in such domains as global spending priorities, debt relief, trade policy, and corporate responsibility. HIV/AIDS, tuberculosis and malaria are global problems borne of gross socioeconomic inequality, and their solutions require correspondingly geopolitical solutions.

  19. Readiness in Meeting Globalization Challenges: A Case of Accounting Firms in Malaysia

    Directory of Open Access Journals (Sweden)

    Arfah Salleh

    2007-01-01

    Full Text Available The empirical study explored the relationships between firm’s characteristics and perceived readiness level of Malaysian Institute of Accountants firm members in meeting globalization challenges. In general all respondents indicated low readiness level in penetrating the global market. Seeing that the services sector is growing tremendously during the recent decades, there is a great opportunity for businesses to increase the export services in the foreseeable future to match that of the developed countries. Thus the findings and recommendations of this study provided comprehensive empirical information for entrepreneurs especially those involve in financial sector to actively embark into the global market.

  20. Globalization and Its Challenges for Developing Countries: The Case of Turkish Higher Education

    Science.gov (United States)

    Akar, Hanife

    2010-01-01

    This paper examines the challenges faced by the Turkish higher education system and exposes the inequities and realities educators in a developing nation must struggle with as they try to find a prestigious spot in the knowledge-production industry. After a brief overview of the literature that illustrates how globalization penetrated into each…

  1. Introduction: Building Global Alliances V: The Challenges of Migration For Health Professional Women.

    Science.gov (United States)

    Nichols, Barbara L

    2010-05-01

    The following four articles are based on presentations delivered at Building Global Alliances V: The Challenges of Migration for Health Professional Women, held in Philadelphia on December 7-8, 2008 and hosted by CGFNS International (formerly the Commission on Graduates of Foreign Nursing Schools).

  2. Challenges in Teaching English to Young Learners: Global Perspectives and Local Realities

    Science.gov (United States)

    Copland, Fiona; Garton, Sue; Burns, Anne

    2014-01-01

    Drawing on data from a recent research international research project, this article focuses on the challenges faced by teachers of English to young learners against the backdrop of the global rise of English. A mixed-methods approach was used to obtain the data, including a survey, which was completed by 4,459 teachers worldwide, and case studies,…

  3. Challenges in Teaching English to Young Learners: Global Perspectives and Local Realities

    Science.gov (United States)

    Copland, Fiona; Garton, Sue; Burns, Anne

    2014-01-01

    Drawing on data from a recent research international research project, this article focuses on the challenges faced by teachers of English to young learners against the backdrop of the global rise of English. A mixed-methods approach was used to obtain the data, including a survey, which was completed by 4,459 teachers worldwide, and case studies,…

  4. New Challenges Facing Universities in the Internet-Driven Global Environment

    Science.gov (United States)

    Rajasingham, Lalita

    2011-01-01

    This paper explores some new challenges facing universities in a global multimediated Internet-based environment, as they seek alternative paradigms and options to remain true to their core business. At a time of rapid technological change, and contested, complex concepts associated with globalisation, knowledge is becoming a primary factor of…

  5. 76 FR 10892 - Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor...

    Science.gov (United States)

    2011-02-28

    ... AGENCY Aquatic Ecosystems, Water Quality, and Global Change: Challenges of Conducting Multi-Stressor.... SUMMARY: EPA is announcing the release of the draft report titled, ``Aquatic Ecosystems, Water Quality... relative vulnerability of water quality and aquatic ecosystems, across the United States, to the potential...

  6. Generation of global political priority for early childhood development: the challenges of framing and governance.

    Science.gov (United States)

    Shawar, Yusra Ribhi; Shiffman, Jeremy

    2017-01-07

    Despite progress, early childhood development (ECD) remains a neglected issue, particularly in resource-poor countries. We analyse the challenges and opportunities that ECD proponents face in advancing global priority for the issue. We triangulated among several data sources, including 19 semi-structured interviews with individuals involved in global ECD leadership, practice, and advocacy, as well as peer-reviewed research, organisation reports, and grey literature. We undertook a thematic analysis of the collected data, drawing on social science scholarship on collective action and a policy framework that elucidates why some global initiatives are more successful in generating political priority than others. The analysis indicates that the ECD community faces two primary challenges in advancing global political priority. The first pertains to framing: generation of internal consensus on the definition of the problem and solutions, agreement that could facilitate the discovery of a public positioning of the issue that could generate political support. The second concerns governance: building of effective institutions to achieve collective goals. However, there are multiple opportunities to advance political priority for ECD, including an increasingly favourable political environment, advances in ECD metrics, and the existence of compelling arguments for investment in ECD. To advance global priority for ECD, proponents will need to surmount the framing and governance challenges and leverage these opportunities. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Ethical Challenges Facing Greenland in the Present Era of Globalization: Towards Global Responsibility

    Directory of Open Access Journals (Sweden)

    Jacob Dahl Rendtorff

    2013-06-01

    Full Text Available Recently, the developments of ethics and politics in the Arctic region have again become an issue for international discussion. One main issue is the problem of climate change and sustainability of the Arctic region. This problem is linked to the issue of exploitation of natural resources in the Arctic region, not at least in Greenland. Indeed, the general issue is how we should define ethics of the environment and sustainability as a general principle for the Arctic region. It is important to discuss what is at stake and how we define the problem in relation to the different participating stakeholders. This paper deals with these problems as a case for global ethics and it proposes a vision of ethical and political responsibility for sustainable development in order to deal with such problems.

  8. Challenges for writing Church History in Africa in a global age: A Zambian perspective

    Directory of Open Access Journals (Sweden)

    J. W. Hofmeyr

    1998-08-01

    Full Text Available The purpose of this article is to discuss the six big challenges which should be taken into consideration in addressing the issue of doing and writing church history in Africa. The thesis of the article is that these challenges are not taken into sufficient consideration by the outside world as from a Third World perspective. Experts in the field of writing church history, in general, have stated and clearly articulated that no history is ever easy to write. What makes it particularly difficult to write church history in Africa, are the different perspectives on the establishment of the church on our continent. What we have, are pieces of information that have been distorted by prejudice and bias as each generation came to be. Addressing these challenges will, however, help us to overcome certain barriers in our study of African church history.

  9. The role of ICTs in higher education in South Africa: One strategy for addressing teaching and learning challenges

    National Research Council Canada - National Science Library

    Shaheeda Jaffer; Dick Ng'ambi; Laura Czerniewicz

    2007-01-01

    .... In developing countries where higher education is fraught with serious challenges at multiple levels, there is increasing pressure to ensure that technological possibilities are viewed in the context...

  10. The Challenges of Applying Planetary Boundaries as a Basis for Strategic Decision-Making in Companies with Global Supply Chains

    Directory of Open Access Journals (Sweden)

    Roland Clift

    2017-02-01

    Full Text Available The Planetary Boundaries (PB framework represents a significant advance in specifying the ecological constraints on human development. However, to enable decision-makers in business and public policy to respect these constraints in strategic planning, the PB framework needs to be developed to generate practical tools. With this objective in mind, we analyse the recent literature and highlight three major scientific and technical challenges in operationalizing the PB approach in decision-making: first, identification of thresholds or boundaries with associated metrics for different geographical scales; second, the need to frame approaches to allocate fair shares in the ‘safe operating space’ bounded by the PBs across the value chain and; third, the need for international bodies to co-ordinate the implementation of the measures needed to respect the Planetary Boundaries. For the first two of these challenges, we consider how they might be addressed for four PBs: climate change, freshwater use, biosphere integrity and chemical pollution and other novel entities. Four key opportunities are identified: (1 development of a common system of metrics that can be applied consistently at and across different scales; (2 setting ‘distance from boundary’ measures that can be applied at different scales; (3 development of global, preferably open-source, databases and models; and (4 advancing understanding of the interactions between the different PBs. Addressing the scientific and technical challenges in operationalizing the planetary boundaries needs be complemented with progress in addressing the equity and ethical issues in allocating the safe operating space between companies and sectors.

  11. Current medical research funding and frameworks are insufficient to address the health risks of global environmental change.

    Science.gov (United States)

    Ebi, Kristie L; Semenza, Jan C; Rocklöv, Joacim

    2016-11-11

    Three major international agreements signed in 2015 are key milestones for transitioning to more sustainable and resilient societies: the UN 2030 Agenda for Sustainable Development; the Sendai Framework for Disaster Risk Reduction; and the Paris Agreement under the United Nations Framework Convention on Climate Change. Together, these agreements underscore the critical importance of understanding and managing the health risks of global changes, to ensure continued population health improvements in the face of significant social and environmental change over this century. BODY: Funding priorities of major health institutions and organizations in the U.S. and Europe do not match research investments with needs to inform implementation of these international agreements. In the U.S., the National Institutes of Health commit 0.025 % of their annual research budget to climate change and health. The European Union Seventh Framework Programme committed 0.08 % of the total budget to climate change and health; the amount committed under Horizon 2020 was 0.04 % of the budget. Two issues apparently contributing to this mismatch are viewing climate change primarily as an environmental problem, and therefore the responsibility of other research streams; and narrowly framing research into managing the health risks of climate variability and change from the perspective of medicine and traditional public health. This reductionist, top-down perspective focuses on proximate, individual level risk factors. While highly successful in reducing disease burdens, this framing is insufficient to protect health and well-being over a century that will be characterized by profound social and environmental changes. International commitments in 2015 underscored the significant challenges societies will face this century from climate change and other global changes. However, the low priority placed on understanding and managing the associated health risks by national and international research

  12. Pharmaceutical digital marketing and governance: illicit actors and challenges to global patient safety and public health.

    Science.gov (United States)

    Mackey, Tim K; Liang, Bryan A

    2013-10-16

    Digital forms of direct-to-consumer pharmaceutical marketing (eDTCA) have globalized in an era of free and open information exchange. Yet, the unregulated expansion of eDTCA has resulted in unaddressed global public health threats. Specifically, illicit online pharmacies are engaged in the sale of purportedly safe, legitimate product that may in fact be counterfeit or substandard. These cybercriminal actors exploit available eDTCA mediums over the Internet to market their suspect products globally. Despite these risks, a detailed assessment of the public health, patient safety, and cybersecurity threats and governance mechanisms to address them has not been conducted. Illicit online pharmacies represent a significant global public health and patient safety risk. Existing governance mechanisms are insufficient and include lack of adequate adoption in national regulation, ineffective voluntary governance mechanisms, and uneven global law enforcement efforts that have allowed proliferation of these cybercriminals on the web. In order to effectively address this multistakeholder threat, inclusive global governance strategies that engage the information technology, law enforcement and public health sectors should be established. Effective global "eHealth Governance" focused on cybercrime is needed in order to effectively combat illicit online pharmacies. This includes building upon existing Internet governance structures and coordinating partnership between the UN Office of Drugs and Crime that leads the global fight against transnational organized crime and the Internet Governance Forum that is shaping the future of Internet governance. Through a UNODC-IGF governance mechanism, investigation, detection and coordination of activities against illicit online pharmacies and their misuse of eDTCA can commence.

  13. Pharmaceutical digital marketing and governance: illicit actors and challenges to global patient safety and public health

    Science.gov (United States)

    2013-01-01

    Background Digital forms of direct-to-consumer pharmaceutical marketing (eDTCA) have globalized in an era of free and open information exchange. Yet, the unregulated expansion of eDTCA has resulted in unaddressed global public health threats. Specifically, illicit online pharmacies are engaged in the sale of purportedly safe, legitimate product that may in fact be counterfeit or substandard. These cybercriminal actors exploit available eDTCA mediums over the Internet to market their suspect products globally. Despite these risks, a detailed assessment of the public health, patient safety, and cybersecurity threats and governance mechanisms to address them has not been conducted. Discussion Illicit online pharmacies represent a significant global public health and patient safety risk. Existing governance mechanisms are insufficient and include lack of adequate adoption in national regulation, ineffective voluntary governance mechanisms, and uneven global law enforcement efforts that have allowed proliferation of these cybercriminals on the web. In order to effectively address this multistakeholder threat, inclusive global governance strategies that engage the information technology, law enforcement and public health sectors should be established. Summary Effective global “eHealth Governance” focused on cybercrime is needed in order to effectively combat illicit online pharmacies. This includes building upon existing Internet governance structures and coordinating partnership between the UN Office of Drugs and Crime that leads the global fight against transnational organized crime and the Internet Governance Forum that is shaping the future of Internet governance. Through a UNODC-IGF governance mechanism, investigation, detection and coordination of activities against illicit online pharmacies and their misuse of eDTCA can commence. PMID:24131576

  14. Globalization Education and New Realities (Keynote Address, Midwest History of Education Society Annual Meeting, 2005, Chicago, Illinois)

    Science.gov (United States)

    Watkins, William H.

    2006-01-01

    A central argument of this essay suggests that the truth of globalization is little known to the body politic as it is enmeshed in the dynamics of capitalist accumulation, avarice, and despotism. This project hopes to first locate, and then unmask the realities of globalization, warts and all. Gaining some knowledge of globalization, the…

  15. The Use of Kanban to Alleviate Collaboration and Communication Challenges of Global Software Development

    Directory of Open Access Journals (Sweden)

    Maureen Tanner

    2017-05-01

    Full Text Available Aim/Purpose: This paper aims to describe how various Kanban elements can help alleviate two prominent types of challenges, communication and collaboration in Global Software Development (GSD. Background: Iterative and Lean development methodologies like Kanban have gained significance in the software development industry, both in the co-located and globally distributed contexts. However, little is known on how such methodologies can help mitigate various challenges in that occur in a globally distributed software development context. Methodology: The study was conducted using a single-case study based on a general inductive approach to analysis and theory development. Through the literature review, collaboration and communication challenges that GSD teams face were identified. Data collected through semi-structured interviews was then inductively analyzed to describe how the case-study teams employed various Kanban elements to mitigate communication and collaboration challenges they face during GSD. Findings: The study found that some Kanban elements, when properly employed, can help alleviate collaboration and communication challenges that occur within GSD teams. These relate to Inclusion Criteria, Reverse Items, Kanban Board, Policies, Avatars, and Backlog. Contribution: The paper contributes to knowledge by proposing two simple concept maps that detail the specific types of communication and collaboration challenges which can be alleviated by the aforementioned Kanban elements in GSD. Recommendations for Practitioners: This paper is relevant to GSD teams who are seeking ways to enhance their team collaboration and communication as these are the most important elements that contribute to GSD project success. It is recommended that relevant Kanban elements be used to that effect, depending on the challenges that they aim to alleviate. Future Research: Future research can investigate the same research questions (or similar ones using a

  16. Globalization of labour markets challenges, adjustment and policy response in the EU and LDCS

    CERN Document Server

    Kuyvenhoven, Arie; Molle, Willem

    1997-01-01

    To the classical driving forces of migration such as poverty, oppression and war, yet another is being added: globalization. The trend toward globalization has created new opportunities for trade and investment. These have had positive implications for economic growth and living standards. However, they also confront developed and less developed countries (LCDs) with difficult policy choices. Developed Countries (DCs) have to find a compromise between competitiveness and high labour costs, and between trade liberalization and immigration controls. LCDs have to decide whether to export labour or goods, and to accept foreign resources for development rather than migration. While, in the literature, the impact of globalization has been largely studied from specialist perspectives, this volume offers a comprehensive view of the issue. In Globalization of Labour Markets: Challenges, Adjustment and Policy Response in the European Union and Less Developed Countries international experts: Explain the welfare implicat...

  17. GLOBALIZATION AND INTEGRATION INTO THE ECONOMIC AND MONETARY UNION-CHALLENGES FOR BANKS OPERATING IN ROMANIA

    Directory of Open Access Journals (Sweden)

    CORALIA EMILIA POPA

    2012-01-01

    Full Text Available This paper aims to present recent evolution, but also the consequences of globalization of the banking sector, considering different approaches of this phenomenon. Over time, the banking field has undergone important changes in both the applicable law of this area, and through the technologies used in satisfying the customers’ needs. The development of international markets has led to new opportunities and challenges for banks that transformed the domestic financial market into an arena where only the best survive and grow. On these grounds and in strict relation to positive and negative effects of globalization, we can speak of a constant evolution of its most important subsystems - the financial subsystems of the global economy. In this paper special importance is given to the banking field, the article presenting arguments through which this complex phenomenon called globalization may have important consequences on financial supervision and regulation.

  18. Preparing Early Childhood Educators to Address Young Children's Social-Emotional Development and Challenging Behavior: A Survey of Higher Education Programs in Nine States

    Science.gov (United States)

    Hemmeter, Mary Louise; Santos, Rosa Milagros; Ostrosky, Michaelene M.

    2008-01-01

    This article presents results from a survey of faculty members from 2- and 4-year higher education programs in nine states that prepare teachers to work with preschool children. The purpose of the study was to determine how professors address content related to social-emotional development and challenging behaviors, how well prepared they believe…

  19. Power to the People: Addressing Big Data Challenges in Neuroscience by Creating a New Cadre of Citizen Neuroscientists.

    Science.gov (United States)

    Roskams, Jane; Popović, Zoran

    2016-11-02

    Global neuroscience projects are producing big data at an unprecedented rate that informatic and artificial intelligence (AI) analytics simply cannot handle. Online games, like Foldit, Eterna, and Eyewire-and now a new neuroscience game, Mozak-are fueling a people-powered research science (PPRS) revolution, creating a global community of "new experts" that over time synergize with computational efforts to accelerate scientific progress, empowering us to use our collective cerebral talents to drive our understanding of our brain.

  20. Overcoming Health System Challenges for Women and Children Living With HIV Through the Global Plan.

    Science.gov (United States)

    Modi, Surbhi; Callahan, Tegan; Rodrigues, Jessica; Kajoka, Mwikemo D; Dale, Helen M; Langa, Judite O; Urso, Marilena; Nchephe, Matsepeli I; Bongdene, Helene; Romano, Sostena; Broyles, Laura N

    2017-05-01

    To meet the ambitious targets set by the Global Plan Towards the Elimination of New HIV Infections Among Children by 2015 and Keeping Their Mothers Alive (Global Plan), the initial 22 priority countries quickly developed innovative approaches for overcoming long-standing health systems challenges and providing HIV testing and treatment to pregnant and breastfeeding women and their infants. The Global Plan spurred programs for prevention of mother-to-child HIV transmission to integrate HIV-related care and treatment into broader maternal, newborn, and child health services; expand the effectiveness of the health workforce through task sharing; extend health services into communities; strengthen supply chain and commodity management systems; reduce diagnostic and laboratory hurdles; and strengthen strategic supervision and mentorship. The article reviews the ongoing challenges for prevention of mother-to-child HIV transmission programs as they continue to strive for elimination of vertical transmission of HIV infection in the post-Global Plan era. Although progress has been rapid, health systems still face important challenges, particularly follow-up and diagnosis of HIV-exposed infants, continuity of care, and the promotion of services that are respectful and client centered.

  1. Comparative and International Education Society (CIES) Facing the Twenty-First Century: Challenges and Contributions. Presidential Address.

    Science.gov (United States)

    Arnove, Robert F.

    2001-01-01

    Examines challenges to comparative and international education in the areas of epistemological approaches, research methodology, philosophical considerations, and dissemination of findings; the field's contributions in questioning assumptions about school-society relationships, identifying the benefits and dangers of "borrowing" educational…

  2. Turkey-USA relations in an age of regional and global turmoil: challenges and prospects introduction

    OpenAIRE

    Öniş, Ziya; Yılmaz, Şuhnaz

    2013-01-01

    TURKEY-US RELATIONS IN AN AGE OF REGIONAL AND GLOBAL TURMOIL: CHALLENGES AND PROSPECTS EDITORIAL INTRODUCTION Ziya Öniş and Şuhnaz Yılmaz This special issue on Turkish-American relations with a specific focus on the Middle East aims to analyze a complex web of relations at a critical regional and global juncture, with important implications well beyond bilateral relations. The idea for this special issue emerged during the “Turkish-American Alliance in a Volatile Region: ...

  3. E-LEARNING AND THE GLOBAL DIVIDE: The Challenges Facing Distance Education in Africa

    Directory of Open Access Journals (Sweden)

    Bamidele A. OJO

    2009-07-01

    Full Text Available This paper examines the question of distance education and its pivotal role in promoting social change and development in Africa. It also discussed within the context of the global digital divide and the ongoing need for collaborative effort at global education, the limitation imposed by the socio-economic and political environment on the continent. The paper in its findings conclude that the crisis within African societies constitutes a serious challenge to the implementation of and the effectiveness of distance education in Africa and therefore contributes to the widening of the digital divide rather than reducing it.

  4. How can we exploit above-belowground interactions to assist in addressing the challenges of food security?

    Science.gov (United States)

    Orrell, Peter; Bennett, Alison E

    2013-10-30

    Can above-belowground interactions help address issues of food security? We address this question in this manuscript, and review the intersection of above-belowground interactions and food security. We propose that above-belowground interactions could address two strategies identified by Godfray etal. (2010): reducing the Yield Gap, and Increasing Production Limits. In particular, to minimize the difference between potential and realized production (The Yield Gap) above-belowground interactions could be manipulated to reduce losses to pests and increase crop growth (and therefore yields). To Increase Production Limits we propose two mechanisms: utilizing intercropping (which uses multiple aspects of above-belowground interactions) and breeding for traits that promote beneficial above-belowground interactions, as well as breeding mutualistic organisms to improve their provided benefit. As a result, if they are managed correctly, there is great potential for above-belowground interactions to contribute to food security.

  5. Measuring coverage in MNCH: challenges and opportunities in the selection of coverage indicators for global monitoring.

    Directory of Open Access Journals (Sweden)

    Jennifer Harris Requejo

    Full Text Available Global monitoring of intervention coverage is a cornerstone of international efforts to improve reproductive, maternal, newborn, and child health. In this review, we examine the process and implications of selecting a core set of coverage indicators for global monitoring, using as examples the processes used by the Countdown to 2015 for Maternal, Newborn and Child Survival and the Commission on Accountability for Women's and Children's Health. We describe how the generation of data for global monitoring involves five iterative steps: development of standard indicator definitions and measurement approaches to ensure comparability across countries; collection of high-quality data at the country level; compilation of country data at the global level; organization of global databases; and rounds of data quality checking. Regular and rigorous technical review processes that involve high-level decision makers and experts familiar with indicator measurement are needed to maximize uptake and to ensure that indicators used for global monitoring are selected on the basis of available evidence of intervention effectiveness, feasibility of measurement, and data availability as well as programmatic relevance. Experience from recent initiatives illustrates the challenges of striking this balance as well as strategies for reducing the tensions inherent in the indicator selection process. We conclude that more attention and continued investment need to be directed to global monitoring, to support both the process of global database development and the selection of sets of coverage indicators to promote accountability. The stakes are high, because these indicators can drive policy and program development at the country and global level, and ultimately impact the health of women and children and the communities where they live.

  6. Global Vaccine and Immunization Research Forum: Opportunities and challenges in vaccine discovery, development, and delivery.

    Science.gov (United States)

    Ford, Andrew Q; Touchette, Nancy; Hall, B Fenton; Hwang, Angela; Hombach, Joachim

    2016-03-18

    The World Health Organization, the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, and the Bill & Melinda Gates Foundation convened the first Global Vaccine and Immunization Research Forum (GVIRF) in March 2014. This first GVIRF aimed to track recent progress of the Global Vaccine Action Plan research and development agenda, identify opportunities and challenges, promote partnerships in vaccine research, and facilitate the inclusion of all stakeholders in vaccine research and development. Leading scientists, vaccine developers, and public health officials from around the world discussed scientific and technical challenges in vaccine development, research to improve the impact of immunization, and regulatory issues. This report summarizes the discussions and conclusions from the forum participants.

  7. Policy and Investment Priorities to Reduce Environmental Degradation of the lake Nicaragua Watershed (Cocibolca) : Addressing Key Environmental Challenges - Study 2

    OpenAIRE

    2010-01-01

    Globally, an estimated 24 percent of the disease burden (healthy life years lost) and an estimated 23 percent of all deaths (premature mortality) are attributable to environmental risks (World Health Organization, or WHO 2006). The burden of disease is unequally shared, with the children and the poor being particularly affected. Among children between the ages 0 and 14, the proportion of deaths ...

  8. Research-informed strategies to address educational challenges in a digitally networked world: the EDUsummIT 2013 action agenda

    NARCIS (Netherlands)

    Voogt, J.; Knezek, G.; Searson, M.; Lai, K.W.; Gibson, D.; Khaddage, F.; Mishra, P.; Laferriere, T.; Resta, P.; Fisser, P.; Albion, P.; Searson, M.; Ochoa, M.

    2014-01-01

    EduSummIT is a global community of policy-makers, researchers, and educators working together to move education into the digital age. EDUsummIT 2013 took place in Washington DC and resulted in an action agenda for researchers, policy makers and educators to take concrete steps to move education in

  9. Facing the Challenges of the Future: The 1984 Presidents Academy Award Addresses. AACJC Leadership Bookshelf Series, Number 2.

    Science.gov (United States)

    Tyree, Larry W.; And Others

    These four addresses by community college presidents and chancellors were selected for recognition by the American Association of Community and Junior Colleges' Presidents Academy. After an introduction by Larry W. Tyree, "Interrelationship of Career and Technical Programs with the Humanities," by Rose M. Channing, traces recent trends in…

  10. EPA Grants to Help New York City Communities Address Local Environmental Challenges, Includes Air Sampling Around JFK Airport

    Science.gov (United States)

    (New York, N.Y.) The U.S. Environmental Protection Agency has awarded $84,000 to three New York City organizations working to address environmental contamination in their communities. The grants were awarded under the EPA's Environmental Justice Small Gran

  11. Implementing a Public Health Approach to Addressing Mental Health Needs in a University Setting: Lessons and Challenges

    Science.gov (United States)

    Parcover, Jason; Mays, Sally; McCarthy, Amy

    2015-01-01

    The mental health needs of college students are placing increasing demands on counseling center resources, and traditional outreach efforts may be outdated or incomplete. The public health model provides an approach for reaching more students, decreasing stigma, and addressing mental health concerns before they reach crisis levels. Implementing a…

  12. The Center on the Social and Emotional Foundations for Early Learning: Addressing Challenging Behavior in Infants and Toddlers

    Science.gov (United States)

    Hunter, Amy; Hemmeter, Mary Louise

    2009-01-01

    The Center on the Social and Emotional Foundations for Early Learning (CSEFEL) is a federally funded national resource center designed to support early care and education providers address the social-emotional needs of children birth through age 5 years. Recent research has found that an extraordinarily high number of young children are being…

  13. Implementing a Public Health Approach to Addressing Mental Health Needs in a University Setting: Lessons and Challenges

    Science.gov (United States)

    Parcover, Jason; Mays, Sally; McCarthy, Amy

    2015-01-01

    The mental health needs of college students are placing increasing demands on counseling center resources, and traditional outreach efforts may be outdated or incomplete. The public health model provides an approach for reaching more students, decreasing stigma, and addressing mental health concerns before they reach crisis levels. Implementing a…

  14. Addressing Gender Issues in the Historically Black College and University Community: A Challenge and Call to Action.

    Science.gov (United States)

    Bonner, Florence B.

    2001-01-01

    Black women struggle for parity with men and white women in the U.S. academy. Examines gender issues at historically black colleges and universities (HBCUs), noting patterns of gender inequity and discrimination. These disparities are confounded by and in conflict with issues of race. Addresses the consequence of lack of attention to gender…

  15. GLOBAL CHALLENGES AND TRENDS IN THE TOURISM INDUSTRY; ROMANIA, WHERE TO?

    Directory of Open Access Journals (Sweden)

    FIROIU DANIELA

    2015-06-01

    Full Text Available In the context of an increasingly dynamic global society, adapting to new market conditions becomes a necessity, so that mutations in the tourism industry, as the economic sector to record the fastest ascent, become part of worldwide change. Tourism in the 21st century meets new dimensions as a result of unprecedented economic and technological expansion, the implications of these changes being profound and sometimes even difficult to explain or quantify. Therefore, defining an adequate tourism offer and adapting to market requirements become real challenges for economic agents, challenges that must be managed carefully in order to attain success. Currently, the focus is mainly on the technological factor and the sustainability of tourist activities, which become real progress binders, with strong influence on the entire supply chain. Global outlined trends define new ways to practice tourism, so that the technological evolution marks the transition of the entire travel experience from the offline to the online environment. The mobile segment is the one currently creating the newest opportunities for the development of tourist services, which is based on an increasingly close relationship between operators and tourists. It is to be seen whether Romania, as an emerging tourism market, which owns all necessary assets for a rapid and strong ascent, will be able to turn challenges offered by global dynamics into opportunities or will face the risks induced by it.

  16. Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys.

    Science.gov (United States)

    Barouch, Dan H; Stephenson, Kathryn E; Borducchi, Erica N; Smith, Kaitlin; Stanley, Kelly; McNally, Anna G; Liu, Jinyan; Abbink, Peter; Maxfield, Lori F; Seaman, Michael S; Dugast, Anne-Sophie; Alter, Galit; Ferguson, Melissa; Li, Wenjun; Earl, Patricia L; Moss, Bernard; Giorgi, Elena E; Szinger, James J; Eller, Leigh Anne; Billings, Erik A; Rao, Mangala; Tovanabutra, Sodsai; Sanders-Buell, Eric; Weijtens, Mo; Pau, Maria G; Schuitemaker, Hanneke; Robb, Merlin L; Kim, Jerome H; Korber, Bette T; Michael, Nelson L

    2013-10-24

    The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development. HIV-1 mosaic antigens are bioinformatically optimized immunogens designed for improved coverage of HIV-1 diversity. However, the protective efficacy of such global HIV-1 vaccine antigens has not previously been evaluated. Here, we demonstrate the capacity of bivalent HIV-1 mosaic antigens to protect rhesus monkeys against acquisition of infection following heterologous challenges with the difficult-to-neutralize simian-human immunodeficiency virus SHIV-SF162P3. Adenovirus/poxvirus and adenovirus/adenovirus vector-based vaccines expressing HIV-1 mosaic Env, Gag, and Pol afforded a significant reduction in the per-exposure acquisition risk following repetitive, intrarectal SHIV-SF162P3 challenges. Protection against acquisition of infection correlated with vaccine-elicited binding, neutralizing, and functional nonneutralizing antibodies, suggesting that the coordinated activity of multiple antibody functions may contribute to protection against difficult-to-neutralize viruses. These data demonstrate the protective efficacy of HIV-1 mosaic antigens and suggest a potential strategy for the development of a global HIV-1 vaccine. PAPERCLIP:

  17. Combining Multidisciplinary Science, Quantitative Reasoning and Social Context to Teach Global Sustainability and Prepare Students for 21st Grand Challenges

    Science.gov (United States)

    Myers, J. D.

    2011-12-01

    The Earth's seven billion humans are consuming a growing proportion of the world's ecosystem products and services. Human activity has also wrought changes that rival the scale of many natural geologic processes, e.g. erosion, transport and deposition, leading to recognition of a new geological epoch, the Anthropocene. Because of these impacts, several natural systems have been pushed beyond the planetary boundaries that made the Holocene favorable for the expansion of humanity. Given these human-induced stresses on natural systems, global citizens will face an increasing number of grand challenges. Unfortunately, traditional discipline-based introductory science courses do little to prepare students for these complex, scientifically-based and technologically-centered challenges. With NSF funding, an introductory, integrated science course stressing quantitative reasoning and social context has been created at UW. The course (GEOL1600: Global Sustainability: Managing the Earth's Resources) is a lower division course designed around the energy-water-climate (EWC) nexus and integrating biology, chemistry, Earth science and physics. It melds lectures, lecture activities, reading questionnaires and labs to create a learning environment that examines the EWT nexus from a global through regional context. The focus on the EWC nexus, while important socially and intended to motivate students, also provides a coherent framework for identifying which disciplinary scientific principles and concepts to include in the course: photosynthesis and deep time (fossil fuels), biogeochemical cycles (climate), chemical reactions (combustion), electromagnetic radiation (solar power), nuclear physics (nuclear power), phase changes and diagrams (water and climate), etc. Lecture activities are used to give students the practice they need to make quantitative skills routine and automatic. Laboratory exercises on energy (coal, petroleum, nuclear power), water (in Bangladesh), energy

  18. Challenges, health implications, and advocacy opportunities for lesbian, gay, bisexual, and transgender global health providers.

    Science.gov (United States)

    Nagata, Jason M

    2017-01-01

    In this commentary, I reflect on challenges with conducting global health research internationally as a lesbian, gay, bisexual, and transgender (LGBT) person, grapple with decisions related to coming out in regions with anti-LGBT laws, and outline the risks and benefits of different advocacy options related to the promotion of LGBT health globally. Despite significant advances in LGBT rights in many countries, homosexuality remains illegal in many others. Using a critical medical anthropology framework, I argue that anti-LGBT laws constitute structural violence and have many detrimental consequences including discrimination and violence; poorer mental and physical health outcomes; and risky sexual behaviors. As a global health provider, there are many options for the promotion of LGBT health worldwide.

  19. Remarks on the Future of the European Union: Domestic and Global Challenges Ahead

    Directory of Open Access Journals (Sweden)

    András Inotai

    2011-12-01

    Full Text Available This paper highlights the main consequences that the crisis has put on the European Union, regarding four major areas: financial, macroeconomic, social and mental-ideological. Also, it aims to tackle some key challenges for the European Union: the revival of international trade; the prevention of the rise of protectionism on the global scale; the need to find a solution to the dilemma between continued stimulus and financial consolidation in general, and between the ambitious goals of the Europe 2020 project and the current fiscal restrictions; the growth of public support across Europe for a financial consolidation strategy based on cutting spending; the impact of the financial and macroeconomic crisis on several sectors; and the deficiencies of the „European construction” indicated by the global crisis. Furthermore, it proposes four main questions for which EU has to provide clear answers in order to become a real global player. The questions concern the „European identity”, the „European values”, the EU strategy paper establishing its mission for the next period and the importance of a strong leadership implementing the strategy. In the end, the most important challenge seems to be how the EU can remain a global economic actor and become a more influential political player in the network of rapidly changing international power relations.

  20. ICT security curriculum or how to respond to current global challenges

    Directory of Open Access Journals (Sweden)

    Marian Silviu Poboroniuc

    2017-01-01

    Full Text Available The paper presents some results obtained through the implementation of the Erasmus LLP “SALEIE” (Strategic Alignment of Electrical and Information Engineering in European Higher Education Institutions. The aim of the project was to bring together experts from European universities to enhance the competitiveness of Electrical and Information Engineering (EIE education within Europe, especially in relation to modern global technical challenges and to provide higher education models in a few EIE fields in accordance with these challenges. One of the outcomes of the project was a new ICT (Information and Computer Technology Security curriculum for bachelor and master levels. The research methodology comprised such stages as: identifying the most important current global challenges, conducting a survey related to existing EIE programs in order to establish the top-level criteria for an EIE curriculum, analyzing the results of the survey, obtaining the industry feedback related to technical and non-technical skills required for the specific field, and proposing a new curriculum for ICT Security programmes to respond to the modern technical challenges and to meet the needs of the industry, students, academics and graduates. As future work we will focus on stakeholder assessment in the EIE field and, based on the resulting feedback, on improving the ICT Security curriculum.