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Sample records for adaptive biasing force

  1. Extended Adaptive Biasing Force Algorithm. An On-the-Fly Implementation for Accurate Free-Energy Calculations.

    Science.gov (United States)

    Fu, Haohao; Shao, Xueguang; Chipot, Christophe; Cai, Wensheng

    2016-08-01

    Proper use of the adaptive biasing force (ABF) algorithm in free-energy calculations needs certain prerequisites to be met, namely, that the Jacobian for the metric transformation and its first derivative be available and the coarse variables be independent and fully decoupled from any holonomic constraint or geometric restraint, thereby limiting singularly the field of application of the approach. The extended ABF (eABF) algorithm circumvents these intrinsic limitations by applying the time-dependent bias onto a fictitious particle coupled to the coarse variable of interest by means of a stiff spring. However, with the current implementation of eABF in the popular molecular dynamics engine NAMD, a trajectory-based post-treatment is necessary to derive the underlying free-energy change. Usually, such a posthoc analysis leads to a decrease in the reliability of the free-energy estimates due to the inevitable loss of information, as well as to a drop in efficiency, which stems from substantial read-write accesses to file systems. We have developed a user-friendly, on-the-fly code for performing eABF simulations within NAMD. In the present contribution, this code is probed in eight illustrative examples. The performance of the algorithm is compared with traditional ABF, on the one hand, and the original eABF implementation combined with a posthoc analysis, on the other hand. Our results indicate that the on-the-fly eABF algorithm (i) supplies the correct free-energy landscape in those critical cases where the coarse variables at play are coupled to either each other or to geometric restraints or holonomic constraints, (ii) greatly improves the reliability of the free-energy change, compared to the outcome of a posthoc analysis, and (iii) represents a negligible additional computational effort compared to regular ABF. Moreover, in the proposed implementation, guidelines for choosing two parameters of the eABF algorithm, namely the stiffness of the spring and the mass

  2. Gender bias in the force concept inventory?

    Science.gov (United States)

    Dietz, R. D.; Pearson, R. H.; Semak, M. R.; Willis, C. W.

    2012-02-01

    Could the well-established fact that males tend to score higher than females on the Force Concept Inventory (FCI) be due to gender bias in the questions? The eventual answer to the question hinges on the definition of bias. We assert that a question is biased only if a factor other than ability (in this case gender) affects the likelihood that a student will answer the question correctly. The statistical technique of differential item functioning allows us to control for ability in our analysis of student performance on each of the thirty FCI questions. This method uses the total score on the FCI as the measure of ability. We conclude that the evidence for gender bias in the FCI questions is marginal at best.

  3. Bias Adaptation for Vocal Tract Length Normalization

    OpenAIRE

    Saheer, Lakshmi; Yamagishi, Junichi; Garner, Philip N.; Dines, John

    2013-01-01

    Vocal tract length normalisation (VTLN) is a well known rapid adaptation technique. VTLN as a linear transformation in the cepstral domain results in the scaling and translation factors. The warping factor represents the spectral scaling parameter. While, the translation factor represented by bias term captures more speaker characteristics especially in a rapid adaptation framework without having the risk of over-fitting. This paper presents a complete and comprehensible derivation of the bia...

  4. Biased diffusion in tubes of alternating diameter: Numerical study over a wide range of biasing force

    Energy Technology Data Exchange (ETDEWEB)

    Makhnovskii, Yurii A. [Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Leninsky Prospect 29, Moscow 119991 (Russian Federation); Berezhkovskii, Alexander M. [Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20819 (United States); Antipov, Anatoly E. [Faculty of Fundamental Physics and Chemical Engineering, Moscow State University, GSP-1, 1-51 Leninskie Gory, Moscow 119991 (Russian Federation); Zitserman, Vladimir Yu. [Joint Institute for High Temperatures, Russian Academy of Sciences, Izhorskaya 13, Bldg. 2, Moscow 125412 (Russian Federation)

    2015-11-07

    This paper is devoted to particle transport in a tube formed by alternating wide and narrow sections, in the presence of an external biasing force. The focus is on the effective transport coefficients—mobility and diffusivity, as functions of the biasing force and the geometric parameters of the tube. Dependences of the effective mobility and diffusivity on the tube geometric parameters are known in the limiting cases of no bias and strong bias. The approximations used to obtain these results are inapplicable at intermediate values of the biasing force. To bridge the two limits Brownian dynamics simulations were run to determine the transport coefficients at intermediate values of the force. The simulations were performed for a representative set of tube geometries over a wide range of the biasing force. They revealed that there is a range of the narrow section length, where the force dependence of the mobility has a maximum. In contrast, the diffusivity is a monotonically increasing function of the force. A simple formula is proposed, which reduces to the known dependences of the diffusivity on the tube geometric parameters in both limits of zero and strong bias. At intermediate values of the biasing force, the formula catches the diffusivity dependence on the narrow section length, if the radius of these sections is not too small.

  5. Sex-biased dispersal promotes adaptive parental effects

    OpenAIRE

    Franc Alain; Revardel Emmanuelle; Petit Rémy J

    2010-01-01

    Abstract Background In heterogeneous environments, sex-biased dispersal could lead to environmental adaptive parental effects, with offspring selected to perform in the same way as the parent dispersing least, because this parent is more likely to be locally adapted. We investigate this hypothesis by simulating varying levels of sex-biased dispersal in a patchy environment. The relative advantage of a strategy involving pure maternal (or paternal) inheritance is then compared with a strategy ...

  6. Adaptive beamforming and phase bias compensation for GNSS receiver

    Institute of Scientific and Technical Information of China (English)

    Hongwei Zhao; Baowang Lian; Juan Feng

    2015-01-01

    Adaptive antenna arrays have been used to mitigate the interference on global navigation satel ite system (GNSS) re-ceivers. The performance of interference mitigation depends on the beamforming algorithms adopted by the antenna array. However, the adaptive beamforming wil change the array pattern in real-time, which has the potential to introduce phase center biases into the antenna array. For precise applications, these phase biases must be mitigated or compensated because they wil bring errors in code phase and carrier phase measurements. A novel adaptive beamforming algorithm is proposed firstly, then the phase bias induced by the proposed algorithm is estimated, and final y a com-pensation strategy is addressed. Simulations demonstrate that the proposed beamforming algorithm suppresses effectively the strong interference and improves significantly the capturing performance of GNSS signals. Simultaneously, the bias compensation method avoids the loss of the carrier phase lock and reduces the phase measurement errors for GNSS receivers.

  7. Adaptive Unified Biased Estimators of Parameters in Linear Model

    Institute of Scientific and Technical Information of China (English)

    Hu Yang; Li-xing Zhu

    2004-01-01

    To tackle multi collinearity or ill-conditioned design matrices in linear models,adaptive biased estimators such as the time-honored Stein estimator,the ridge and the principal component estimators have been studied intensively.To study when a biased estimator uniformly outperforms the least squares estimator,some suficient conditions are proposed in the literature.In this paper,we propose a unified framework to formulate a class of adaptive biased estimators.This class includes all existing biased estimators and some new ones.A suficient condition for outperforming the least squares estimator is proposed.In terms of selecting parameters in the condition,we can obtain all double-type conditions in the literature.

  8. The infrastructure bias in Vietnamese climate change adaptation

    OpenAIRE

    Lindegaard, Lily Salloum

    2013-01-01

    This working paper examines the climate change adaptation strategies of meso-level, or mid-level, government institutions in central Vietnam. It reveals a significant bias towards infrastructure over so-called 'soft' solutions. The main drivers behind this bias - a techno - cratic desire for visible solutions, a need to secure socio-economic development and aspects of the state apparatus itself - are explored and explained using data from interviews with government officials. Ultimately, the ...

  9. Digit forces bias sensorimotor transformations underlying control of fingertip position

    Directory of Open Access Journals (Sweden)

    Daisuke eShibata

    2014-08-01

    Full Text Available Humans are able to modulate digit forces as a function of position despite changes in digit placement that might occur from trial to trial or when changing grip type for object manipulation. Although this phenomenon is likely to rely on sensing the position of the digits relative to each other and the object, the underlying mechanisms remain unclear. To address this question, we asked subjects (n = 30 to match perceived vertical distance between the center of pressure (CoP of the thumb and index finger pads (dy of the right hand (reference hand using the same hand (test hand. The digits of reference hand were passively placed collinearly (dy = 0 mm. Subjects were then asked to exert different combinations of normal and tangential digit forces (Fn and Ftan, respectively using the reference hand and then match the memorized dy using the test hand. The reference hand exerted Ftan of thumb and index finger in either same or opposite direction. We hypothesized that, when the tangential forces of the digits are produced in opposite directions, matching error (1 would be biased toward the directions of the tangential forces, and (2 would be greater when the remembered relative contact points are matched with negligible digit force production. For the test hand, digit forces were either negligible (0.5-1 N, 0 ± 0.25 N; Experiment 1 or the same as those exerted by the reference hand (Experiment 2. Matching error was biased towards the direction of digit tangential forces: thumb CoP was placed higher than the index finger CoP when thumb and index finger Ftan were directed upward and downward, respectively, and vice versa (p < 0.001. However, matching error was not dependent on whether the reference and test hand exerted similar or different forces. We propose that the expected sensory consequence of motor commands for tangential forces in opposite directions overrides estimation of fingertip position through haptic sensory feedback.

  10. Using forced choice to test belief bias in syllogistic reasoning.

    Science.gov (United States)

    Trippas, Dries; Verde, Michael F; Handley, Simon J

    2014-12-01

    In deductive reasoning, believable conclusions are more likely to be accepted regardless of their validity. Although many theories argue that this belief bias reflects a change in the quality of reasoning, distinguishing qualitative changes from simple response biases can be difficult (Dube, Rotello, & Heit, 2010). We introduced a novel procedure that controls for response bias. In Experiments 1 and 2, the task required judging which of two simultaneously presented syllogisms was valid. Surprisingly, there was no evidence for belief bias with this forced choice procedure. In Experiment 3, the procedure was modified so that only one set of premises was viewable at a time. An effect of beliefs emerged: unbelievable conclusions were judged more accurately, supporting the claim that beliefs affect the quality of reasoning. Experiments 4 and 5 replicated and extended this finding, showing that the effect was mediated by individual differences in cognitive ability and analytic cognitive style. Although the positive findings of Experiments 3-5 are most relevant to the debate about the mechanisms underlying belief bias, the null findings of Experiments 1 and 2 offer insight into how the presentation of an argument influences the manner in which people reason. PMID:25218460

  11. A Nonlinear Adaptive Filter for Gyro Thermal Bias Error Cancellation

    Science.gov (United States)

    Galante, Joseph M.; Sanner, Robert M.

    2012-01-01

    Deterministic errors in angular rate gyros, such as thermal biases, can have a significant impact on spacecraft attitude knowledge. In particular, thermal biases are often the dominant error source in MEMS gyros after calibration. Filters, such as J\\,fEKFs, are commonly used to mitigate the impact of gyro errors and gyro noise on spacecraft closed loop pointing accuracy, but often have difficulty in rapidly changing thermal environments and can be computationally expensive. In this report an existing nonlinear adaptive filter is used as the basis for a new nonlinear adaptive filter designed to estimate and cancel thermal bias effects. A description of the filter is presented along with an implementation suitable for discrete-time applications. A simulation analysis demonstrates the performance of the filter in the presence of noisy measurements and provides a comparison with existing techniques.

  12. Codon Usage Bias and Determining Forces in Taenia solium Genome.

    Science.gov (United States)

    Yang, Xing; Ma, Xusheng; Luo, Xuenong; Ling, Houjun; Zhang, Xichen; Cai, Xuepeng

    2015-12-01

    The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome. PMID:26797435

  13. Codon Usage Bias and Determining Forces in Taenia solium Genome.

    Science.gov (United States)

    Yang, Xing; Ma, Xusheng; Luo, Xuenong; Ling, Houjun; Zhang, Xichen; Cai, Xuepeng

    2015-12-01

    The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome.

  14. Distributed force probe bending model of critical dimension atomic force microscopy bias

    Science.gov (United States)

    Ukraintsev, Vladimir A.; Orji, Ndubuisi G.; Vorburger, Theodore V.; Dixson, Ronald G.; Fu, Joseph; Silver, Rick M.

    2013-04-01

    Critical dimension atomic force microscopy (CD-AFM) is a widely used reference metrology technique. To characterize modern semiconductor devices, small and flexible probes, often 15 to 20 nm in diameter, are used. Recent studies have reported uncontrolled and significant probe-to-probe bias variation during linewidth and sidewall angle measurements. To understand the source of these variations, tip-sample interactions between high aspect ratio features and small flexible probes, and their influence on measurement bias, should be carefully studied. Using theoretical and experimental procedures, one-dimensional (1-D) and two-dimensional (2-D) models of cylindrical probe bending relevant to carbon nanotube (CNT) AFM probes were developed and tested. An earlier 1-D bending model was refined, and a new 2-D distributed force (DF) model was developed. Contributions from several factors were considered, including: probe misalignment, CNT tip apex diameter variation, probe bending before snapping, and distributed van der Waals-London force. A method for extracting Hamaker probe-surface interaction energy from experimental probe-bending data was developed. Comparison of the new 2-D model with 1-D single point force (SPF) model revealed a difference of about 28% in probe bending. A simple linear relation between biases predicted by the 1-D SPF and 2-D DF models was found. The results suggest that probe bending can be on the order of several nanometers and can partially explain the observed CD-AFM probe-to-probe variation. New 2-D and three-dimensional CD-AFM data analysis software is needed to take full advantage of the new bias correction modeling capabilities.

  15. Catch trials in force field learning influence adaptation and consolidation of human motor memory

    Directory of Open Access Journals (Sweden)

    Christian eStockinger

    2014-04-01

    Full Text Available Force field studies are a common tool to investigate motor adaptation and consolidation. Thereby, subjects usually adapt their reaching movements to force field perturbations induced by a robotic device. In this context, so-called catch trials, in which the disturbing forces are randomly turned off, are commonly used to detect after-effects of motor adaptation. However, catch trials also produce sudden large motor errors that might influence the motor adaptation and the consolidation process. Yet, the detailed influence is far from clear. Thus, the aim of this study was to investigate the influence of catch trials on motor adaptation and consolidation in force field experiments. Therefore, 105 subjects adapted their reaching movements to robot-generated force fields. The test groups adapted their reaching movements to a force field A followed by learning a second interfering force field B before retest of A (ABA. The control groups were not exposed to force field B (AA. To examine the influence of diverse catch trial ratios, subjects received catch trials during force field adaptation with a probability of either 0%, 10%, 20%, 30%, or 40%, depending on the group. First, the results on motor adaptation revealed significant differences between the diverse catch trial ratio groups. With increasing amount of catch trials, the subjects’ motor performance decreased and subjects’ ability to accurately predict the force field – and therefore internal model formation – was impaired. Second, our results revealed that adapting with catch trials can influence the following consolidation process as indicated by a partial reduction to interference. Here, the optimal catch trial ratio was 30%. However, detection of consolidation seems to be biased by the applied measure of performance.

  16. Multiple Adaptive Fading Schmidt-Kalman Filter for Unknown Bias

    OpenAIRE

    Tai-Shan Lou; Zhi-Hua Wang; Meng-Li Xiao; Hui-Min Fu

    2014-01-01

    Unknown biases in dynamic and measurement models of the dynamic systems can bring greatly negative effects to the state estimates when using a conventional Kalman filter algorithm. Schmidt introduces the “consider” analysis to account for errors in both the dynamic and measurement models due to the unknown biases. Although the Schmidt-Kalman filter “considers” the biases, the uncertain initial values and incorrect covariance matrices of the unknown biases still are not considered. To solve th...

  17. An Adaptive Body-Bias Generator for Low Voltage CMOS VLSI Circuits

    OpenAIRE

    Ashok Srivastava; Chuang Zhang

    2008-01-01

    A CMOS body-bias generating circuit has been designed for generating adaptive body-biases for MOSFETs in CMOS circuits for low voltage operation. The circuit compares the frequency of an internal ring oscillator with an external reference clock. When the reference clock is “high,” a forward body-bias is generated. When the reference clock is “low,” a reverse body-bias is generated. The forward body bias is limited to no more than 0.4 V to avoid CMOS latchup. The reverse body bias is limited t...

  18. On the nature of cultural transmission networks: evidence from Fijian villages for adaptive learning biases

    OpenAIRE

    Henrich, Joseph; Broesch, James

    2011-01-01

    Unlike other animals, humans are heavily dependent on cumulative bodies of culturally learned information. Selective processes operating on this socially learned information can produce complex, functionally integrated, behavioural repertoires—cultural adaptations. To understand such non-genetic adaptations, evolutionary theorists propose that (i) natural selection has favoured the emergence of psychological biases for learning from those individuals most likely to possess adaptive informatio...

  19. Current-Induced Forces and Hot Spots in Biased Nanojunctions

    DEFF Research Database (Denmark)

    Lu, Jing Tao; Christensen, Rasmus Bjerregaard; Wang, Jian-Sheng;

    2015-01-01

    We investigate theoretically the interplay of current-induced forces (CIFs), Joule heating, and heat transport inside a current-carrying nanoconductor. We find that the CIFs, due to the electron-phonon coherence, can control the spatial heat dissipation in the conductor. This yields a significant...

  20. The Air Force Officer Qualifying Test: Validity, Fairness, and Bias. Technical Report

    Science.gov (United States)

    Hardison, Chaitra M.; Sims, Carra S.; Wong, Eunice C.

    2010-01-01

    The Air Force has long recognized the importance of selecting the most qualified officers possible. For more than 60 years, it has relied on the Air Force Officer Qualifying Test (AFOQT) as one measure of those qualifications. A variety of concerns have been raised about whether the AFOQT is biased, too expensive, or even valid for predicting…

  1. Self-Biased-SMA Drive PU Microgripper with Force Sensing in Visual Servo

    OpenAIRE

    Ren-Jung Chang; Chih-Cheng Shiu; Chih-Yi Cheng

    2013-01-01

    An innovative design of a polyurethane microgripper system with force sensor is developed for the measurement of gripping force in vision-based control. A microgripper mechanism integrated with a force sensing arm is fabricated by an excimer laser. The microgripper is actuated by a self-biased-SMA (Shape Memory Alloy) actuator. A computer-vision method through the ERES (Extended Regional Edge Statistics) algorithm is employed to track the motion of gripper. The position information of the gri...

  2. Report on Adaptive Force, a specific neuromuscular function

    Directory of Open Access Journals (Sweden)

    Marko Hoff

    2015-08-01

    Full Text Available In real life motions, as well as in sports, the adaptation of the neuromuscular systems to externally applied forces plays an important role. The term Adaptive Force (AF shall characterize the ability of the nerve-muscle-system to adapt to impacting external forces during isometric and eccentric muscle action. The focus in this paper is on the concept of this neuromuscular action, which is not yet described in this way. A measuring system was constructed and evaluated for this specific neuromuscular function, but only the main information of the evaluation of the measuring system and the preliminary reference values are mentioned here, while an article with detailed description will be published separately. This paper concentrates on the three following points: 1 What is the peculiarity of this neuromuscular function, introduced as AF? 2 Is the measuring system able to capture its specific characteristics and which phases of measurement occur? 3 It seems reasonable to discuss if AF can be distinguished and classified among the known force concepts. The article describes the measuring system and how it is able to capture special features of real life motions like submaximal intensities and the subjects’ option to react adequately on external varying forces. Furthermore, within one measurement the system records three different force qualities: the isometric submaximal Adaptive Force (AFiso, the maximal isometric Adaptive Force (AFisomax and the maximal eccentric Adaptive Force (AFeccmax. Each of these phases provide different and unique information on the nerve-muscle-system that are discussed in detail. Important, in terms of the Adaptive Force, seems to be the combination of conditional and coordinative abilities.

  3. Rapid perceptual adaptation to high gravitoinertial force levels Evidence for context-specific adaptation

    Science.gov (United States)

    Lackner, J. R.; Graybiel, A.

    1982-01-01

    Subjects exposed to periodic variations in gravitoinertial force (2-G peak) in parabolic flight maneuvers quickly come to perceive the peak force level as having decreased in intensity. By the end of a 40-parabola flight, the decrease in apparent force is approximately 40%. On successive flight days, the apparent intensity of the force loads seems to decrease as well, indicating a cumulative adaptive effect. None of the subjects reported feeling abnormally 'light' for more than a minute or two after return to 1-G background force levels. The pattern of findings suggests a context-specific adaptation to high-force levels.

  4. Learning to speciate: The biased learning of mate preferences promotes adaptive radiation.

    Science.gov (United States)

    Gilman, R Tucker; Kozak, Genevieve M

    2015-11-01

    Bursts of rapid repeated speciation called adaptive radiations have generated much of Earth's biodiversity and fascinated biologists since Darwin, but we still do not know why some lineages radiate and others do not. Understanding what causes assortative mating to evolve rapidly and repeatedly in the same lineage is key to understanding adaptive radiation. Many species that have undergone adaptive radiations exhibit mate preference learning, where individuals acquire mate preferences by observing the phenotypes of other members of their populations. Mate preference learning can be biased if individuals also learn phenotypes to avoid in mates, and shift their preferences away from these avoided phenotypes. We used individual-based computational simulations to study whether biased and unbiased mate preference learning promotes ecological speciation and adaptive radiation. We found that ecological speciation can be rapid and repeated when mate preferences are biased, but is inhibited when mate preferences are learned without bias. Our results suggest that biased mate preference learning may play an important role in generating animal biodiversity through adaptive radiation.

  5. The Role of Scale and Model Bias in ADAPT's Photospheric Eatimation

    Energy Technology Data Exchange (ETDEWEB)

    Godinez Vazquez, Humberto C. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Hickmann, Kyle Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Arge, Charles Nicholas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Henney, Carl [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-05-20

    The Air Force Assimilative Photospheric flux Transport model (ADAPT), is a magnetic flux propagation based on Worden-Harvey (WH) model. ADAPT would be used to provide a global photospheric map of the Earth. A data assimilation method based on the Ensemble Kalman Filter (EnKF), a method of Monte Carlo approximation tied with Kalman filtering, is used in calculating the ADAPT models.

  6. Constrained adaptive bias correction for satellite radiances assimilation in the ECMWF 4D-Var

    Science.gov (United States)

    Han, Wei; Bormann, Niels

    2016-04-01

    Satellite radiance observations are typically affected by biases that arise from uncertainties in the absolute calibration, the radiative transfer modeling, or other aspects. These biases have to be removed for the successful assimilation of the data in NWP systems. Two key problems have been identified in bias correction: Firstly, bias corrections can drift towards unrealistic values in regions where there is strong model error and relatively few "anchor" observations, ie, observations that have little systematic error and therefore allow the separation between model and observation bias. Examples where this has been particularly problematic are channels sensitive to ozone or stratospheric temperature. Secondly, there is undesired interaction between the quality control and bias correction for observations where bias-corrected observation departures are used for quality control and where these departures show skewed distributions (e.g., in case of cloud detection). In the study, we investigated potential solutions to these problems by providing further constraints using potential available information, such as constraints on the size of the bias correction and innovative bias correction metrics using uncertainty estimation from calibration and radiative transfer. This has been studied in the full ECMWF global 4D-Var system, using data from microwave sounders which are sensitive to stratospheric temperature. The resulting enhanced bias corrections was assessed in the context of other assimilated observations (in particular radiosondes and GPS radio occultation measurements), and through comparisons of MLS temperature retrieval data in stratosphere and mesosphere. The constrained adaptive bias correction of AMSU-A stratospheric sounding channels reduces the biases in stratosphere and improves the medium range forecasts in both stratosphere and troposphere.

  7. The shortwave radiative forcing bias of liquid and ice clouds from MODIS observations

    Directory of Open Access Journals (Sweden)

    L. Oreopoulos

    2009-08-01

    Full Text Available We present an assessment of the plane-parallel bias of the shortwave cloud radiative forcing (SWCRF of liquid and ice clouds at 1 deg scales using global MODIS (Terra and Aqua cloud optical property retrievals for four months of the year 2005 representative of the meteorological seasons. The (negative bias is estimated as the difference of SWCRF calculated using the Plane-Parallel Homogeneous (PPH approximation and the Independent Column Approximation (ICA. PPH calculations use MODIS-derived gridpoint means while ICA calculations use distributions of cloud optical thickness and effective radius. Assisted by a broadband solar radiative transfer algorithm, we find that the absolute value of global SWCRF bias of liquid clouds at the top of the atmosphere is about 6 W m−2 for MODIS overpass times while the SWCRF bias for ice clouds is smaller in absolute terms by about 0.7 W m−2, but with stronger spatial variability. If effective radius variability is neglected and only optical thickness horizontal variations are accounted for, the absolute SWCRF biases increase by about 0.3–0.4 W m−2 on average. Marine clouds of both phases exhibit greater (more negative SWCRF biases than continental clouds. Finally, morning (Terra–afternoon (Aqua differences in SWCRF bias are much more pronounced for ice clouds, up to about 15% (Aqua producing stronger negative bias on global scales, with virtually all contribution to the difference coming from land areas. The substantial magnitude of the global SWCRF bias, which for clouds of both phases is collectively about 4 W m−2 for diurnal averages, should be considered a strong motivation for global climate modelers to accelerate efforts linking cloud schemes capable of subgrid condensate variability with appropriate radiative transfer schemes.

  8. Adapted nested force-gradient integrators for the Schwinger model

    CERN Document Server

    Shcherbakov, Dmitry; Günther, Michael; Finkenrath, Jacob; Knechtli, Francesco; Peardon, Michael

    2016-01-01

    We study a novel class of numerical integrators, the adapted nested force-gradient schemes, used within the molecular dynamics step of the Hybrid Monte Carlo (HMC) algorithm. We test these methods in the Schwinger model on the lattice, a well known benchmark problem. We derive the analytical basis of nested force-gradient type methods and demonstrate the advantage of the proposed approach, namely reduced computational costs compared with other numerical integration schemes in HMC.

  9. Effects of prism adaptation on motor-intentional spatial bias in neglect

    OpenAIRE

    Fortis, Paola; Chen, Peii; Goedert, Kelly M.; Barrett, Anna M.

    2011-01-01

    Prism adaptation may alleviate some symptoms of spatial neglect. However, the mechanism through which this technique works is still unclear. The current study investigated whether prism adaptation differentially affects dysfunction in perceptual-attentional “where” versus motor-intentional “aiming” bias. Five neglect patients performed a line bisection task in which lines were viewed under both normal and right-left reversed viewing conditions, allowing for the fractionation of “where” and “a...

  10. Zero-Variance Zero-Bias Principle for Observables in quantum Monte Carlo: Application to Forces

    CERN Document Server

    Assaraf, R

    2003-01-01

    A simple and stable method for computing accurate expectation values of observable with Variational Monte Carlo (VMC) or Diffusion Monte Carlo (DMC) algorithms is presented. The basic idea consists in replacing the usual ``bare'' estimator associated with the observable by an improved or ``renormalized'' estimator. Using this estimator more accurate averages are obtained: Not only the statistical fluctuations are reduced but also the systematic error (bias) associated with the approximate VMC or (fixed-node) DMC probability densities. It is shown that improved estimators obey a Zero-Variance Zero-Bias (ZVZB) property similar to the usual Zero-Variance Zero-Bias property of the energy with the local energy as improved estimator. Using this property improved estimators can be optimized and the resulting accuracy on expectation values may reach the remarkable accuracy obtained for total energies. As an important example, we present the application of our formalism to the computation of forces in molecular system...

  11. Low-power, enhanced-gain adaptive-biasing-based Operational Transconductance Amplifiers

    DEFF Research Database (Denmark)

    Moradi, Farshad

    A symmetrical PMOS OTA (Operational Transconductance Amplifier) is used to build an advanced rail-to-rail amplifier with improved DC-gain and reduced power consumption. By using the adaptive biasing circuit for two differential inputs, a low stand-by current can be achieved, reducing power consum...

  12. Frequency adaptation for enhanced radiation force amplitude in dynamic elastography.

    Science.gov (United States)

    Ouared, Abderrahmane; Montagnon, Emmanuel; Kazemirad, Siavash; Gaboury, Louis; Robidoux, André; Cloutier, Guy

    2015-08-01

    In remote dynamic elastography, the amplitude of the generated displacement field is directly related to the amplitude of the radiation force. Therefore, displacement improvement for better tissue characterization requires the optimization of the radiation force amplitude by increasing the push duration and/or the excitation amplitude applied on the transducer. The main problem of these approaches is that the Food and Drug Administration (FDA) thresholds for medical applications and transducer limitations may be easily exceeded. In the present study, the effect of the frequency used for the generation of the radiation force on the amplitude of the displacement field was investigated. We found that amplitudes of displacements generated by adapted radiation force sequences were greater than those generated by standard nonadapted ones (i.e., single push acoustic radiation force impulse and supersonic shear imaging). Gains in magnitude were between 20 to 158% for in vitro measurements on agar-gelatin phantoms, and 170 to 336% for ex vivo measurements on a human breast sample, depending on focus depths and attenuations of tested samples. The signal-to-noise ratio was also improved more than 4-fold with adapted sequences. We conclude that frequency adaptation is a complementary technique that is efficient for the optimization of displacement amplitudes. This technique can be used safely to optimize the deposited local acoustic energy without increasing the risk of damaging tissues and transducer elements.

  13. A novel adaptive force control method for IPMC manipulation

    Science.gov (United States)

    Hao, Lina; Sun, Zhiyong; Li, Zhi; Su, Yunquan; Gao, Jianchao

    2012-07-01

    IPMC is a type of electro-active polymer material, also called artificial muscle, which can generate a relatively large deformation under a relatively low input voltage (generally speaking, less than 5 V), and can be implemented in a water environment. Due to these advantages, IPMC can be used in many fields such as biomimetics, service robots, bio-manipulation, etc. Until now, most existing methods for IPMC manipulation are displacement control not directly force control, however, under most conditions, the success rate of manipulations for tiny fragile objects is limited by the contact force, such as using an IPMC gripper to fix cells. Like most EAPs, a creep phenomenon exists in IPMC, of which the generated force will change with time and the creep model will be influenced by the change of the water content or other environmental factors, so a proper force control method is urgently needed. This paper presents a novel adaptive force control method (AIPOF control—adaptive integral periodic output feedback control), based on employing a creep model of which parameters are obtained by using the FRLS on-line identification method. The AIPOF control method can achieve an arbitrary pole configuration as long as the plant is controllable and observable. This paper also designs the POF and IPOF controller to compare their test results. Simulation and experiments of micro-force-tracking tests are carried out, with results confirming that the proposed control method is viable.

  14. Self-Biased-SMA Drive PU Microgripper with Force Sensing in Visual Servo

    Directory of Open Access Journals (Sweden)

    Ren-Jung Chang

    2013-06-01

    Full Text Available An innovative design of a polyurethane microgripper system with force sensor is developed for the measurement of gripping force in vision-based control. A microgripper mechanism integrated with a force sensing arm is fabricated by an excimer laser. The microgripper is actuated by a self-biased-SMA (Shape Memory Alloy actuator. A computer-vision method through the ERES (Extended Regional Edge Statistics algorithm is employed to track the motion of gripper. The position information of the gripping point together with the deflection of the force sensing arm is utilized for sensing force. A fuzzy expert with a PI controller in a visual servo is employed to test the performance of sensing the gripping force in grasping of 38μm diameter metal rod. In the performance test, the microgripper system provides a maximum gripping size of 40μm, a maximum force resolution of 1μN and a maximum gripping force of 58μN.

  15. Nonlinear Adaptive Robust Force Control of Hydraulic Load Simulator

    Institute of Scientific and Technical Information of China (English)

    YAO Jianyong; JIAO Zongxia; YAO Bin; SHANG Yaoxing; DONG Wenbin

    2012-01-01

    This paper deals with the high performance force control of hydraulic load samulator.Many prevtous works for hydraultc force control are based on their linearization equations,but hydraulic inherent nonlinear properties and uncertainties make the conventional feedback proportional-integral-derivative control not yield to high-performance requirements.In this paper,a nonlinear system model is derived and linear parameterization is made for adaptive control.Then a discontinuous projection-based nonlinear adaptive robust force controller is developed for hydraulic load simulator.The proposed controller constructs an asymptotically stable adaptive controller and adaptation laws,which can compensate for the system nonlinearities and uncertain parameters.Meanwhile a well-designed robust controller is also developed to cope with the hydraulic system uncertain nonlinearities.The controller achieves a guaranteed transient performance and final tracking accuracy in the presence of both parametric uncertainties and uncertain nonlinearities; in the absence of uncertain nonlinearities,the scheme also achieves asymptotic tracking performance.Simulation and experiment comparative results are obtained to verify the high-performance nature of the proposed control strategy and the tracking accuracy is greatly improved.

  16. Reduction of systematic biases in regional climate downscaling through ensemble forcing

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Hongwei; Wang, Bin [Chinese Academy of Sciences, LASG, Institute of Atmospheric Physics, Beijing (China); Wang, Bin [University of Hawaii at Manoa, Department of Meteorology, Honolulu, Hawaii (United States); University of Hawaii at Manoa, International Pacific Research Center, Honolulu, Hawaii (United States)

    2012-02-15

    Simulations of the East Asian summer monsoon for the period of 1979-2001 were carried out using the Weather Research and Forecast (WRF) model forced by three reanalysis datasets (NCEP-R2, ERA-40, and JRA-25). The experiments forced by different reanalysis data exhibited remarkable differences, primarily caused by uncertainties in the lateral boundary (LB) moisture fluxes over the Bay of Bengal and the Philippine Sea. The climatological mean water vapor convergence into the model domain computed from ERA-40 was about 24% higher than that from the NCEP-R2 reanalysis. We demonstrate that using the ensemble mean of NCEP-R2, ERA-40, and JRA-25 as LB forcing considerably reduced the biases in the model simulation. The use of ensemble forcing improved the performance in simulated mean circulation and precipitation, inter-annual variation in seasonal precipitation, and daily precipitation. The model simulated precipitation was superior to that in the reanalysis in both climatology and year-to-year variations, indicating the added value of dynamic downscaling. The results suggest that models having better performance under one set of LB forcing might worsen when another set of reanalysis data is used as LB forcing. Use of ensemble mean LB forcing for assessing regional climate model performance is recommended. (orig.)

  17. An adaptive scaling and biasing scheme for OFDM-based visible light communication systems.

    Science.gov (United States)

    Wang, Zhaocheng; Wang, Qi; Chen, Sheng; Hanzo, Lajos

    2014-05-19

    Orthogonal frequency-division multiplexing (OFDM) has been widely used in visible light communication systems to achieve high-rate data transmission. Due to the nonlinear transfer characteristics of light emitting diodes (LEDs) and owing the high peak-to-average-power ratio of OFDM signals, the transmitted signal has to be scaled and biased before modulating the LEDs. In this contribution, an adaptive scaling and biasing scheme is proposed for OFDM-based visible light communication systems, which fully exploits the dynamic range of the LEDs and improves the achievable system performance. Specifically, the proposed scheme calculates near-optimal scaling and biasing factors for each specific OFDM symbol according to the distribution of the signals, which strikes an attractive trade-off between the effective signal power and the clipping-distortion power. Our simulation results demonstrate that the proposed scheme significantly improves the performance without changing the LED's emitted power, while maintaining the same receiver structure. PMID:24921387

  18. Tip-bias-induced domain evolution in PMN-PT transparent ceramics via piezoresponse force microscopy

    Science.gov (United States)

    Zhao, K. Y.; Zhao, W.; Zeng, H. R.; Yu, H. Z.; Ruan, W.; Xu, K. Q.; Li, G. R.

    2015-05-01

    Piezoresponse force microscopy (PFM) was employed to investigate ferroelectric domain structures and their dynamic behavior of lead magnesium niobate-lead titanate [Pb(Mg1/3Nb2/3)O3-xPbTiO3 (PMN-PT)] transparent ceramics under an tip-bias-induced electric field. A remarkable effect of fluctuation of PT content on the domain configurations and domain dynamic response in PMN-PT transparent ferroelectric ceramics were found by PFM. Comparing with PMN-10%PT and PMN-20%PT, the reversed polarization of macrodomain area in PMN-35%PT and PMN-25%PT exhibits a relatively higher response behavior and better polarization retention performance under the PFM tip-bias-induced electric field, which correspond to their unique macroscopic electro-optic properties.

  19. Prism adaptation reverses the local processing bias in patients with right temporo-parietal junction lesions

    OpenAIRE

    Bultitude, Janet H.; Rafal, Robert D.; List, Alexandra

    2009-01-01

    Lesions to the right temporo-parietal cortex commonly result in hemispatial neglect. Lesions to the same area are also associated with hyperattention to local details of a scene and difficulty perceiving the global structure. This local processing bias is an important factor contributing to neglect and may contribute to the higher prevalence of the disorder following right compared with left hemisphere strokes. In recent years, visuomotor adaptation to rightward-shifting prisms has been intro...

  20. Fixation light hue bias revisited: implications for using adaptive optics to study color vision.

    Science.gov (United States)

    Hofer, H J; Blaschke, J; Patolia, J; Koenig, D E

    2012-03-01

    Current vision science adaptive optics systems use near infrared wavefront sensor 'beacons' that appear as red spots in the visual field. Colored fixation targets are known to influence the perceived color of macroscopic visual stimuli (Jameson, D., & Hurvich, L. M. (1967). Fixation-light bias: An unwanted by-product of fixation control. Vision Research, 7, 805-809.), suggesting that the wavefront sensor beacon may also influence perceived color for stimuli displayed with adaptive optics. Despite its importance for proper interpretation of adaptive optics experiments on the fine scale interaction of the retinal mosaic and spatial and color vision, this potential bias has not yet been quantified or addressed. Here we measure the impact of the wavefront sensor beacon on color appearance for dim, monochromatic point sources in five subjects. The presence of the beacon altered color reports both when used as a fixation target as well as when displaced in the visual field with a chromatically neutral fixation target. This influence must be taken into account when interpreting previous experiments and new methods of adaptive correction should be used in future experiments using adaptive optics to study color.

  1. 3D design and electric simulation of a silicon drift detector using a spiral biasing adapter

    Science.gov (United States)

    Li, Yu-yun; Xiong, Bo; Li, Zheng

    2016-09-01

    The detector system of combining a spiral biasing adapter (SBA) with a silicon drift detector (SBA-SDD) is largely different from the traditional silicon drift detector (SDD), including the spiral SDD. It has a spiral biasing adapter of the same design as a traditional spiral SDD and an SDD with concentric rings having the same radius. Compared with the traditional spiral SDD, the SBA-SDD separates the spiral's functions of biasing adapter and the p-n junction definition. In this paper, the SBA-SDD is simulated using a Sentaurus TCAD tool, which is a full 3D device simulation tool. The simulated electric characteristics include electric potential, electric field, electron concentration, and single event effect. Because of the special design of the SBA-SDD, the SBA can generate an optimum drift electric field in the SDD, comparable with the conventional spiral SDD, while the SDD can be designed with concentric rings to reduce surface area. Also the current and heat generated in the SBA are separated from the SDD. To study the single event response, we simulated the induced current caused by incident heavy ions (20 and 50 μm penetration length) with different linear energy transfer (LET). The SBA-SDD can be used just like a conventional SDD, such as X-ray detector for energy spectroscopy and imaging, etc.

  2. Adaptive thinking & leadership simulation game training for special forces officers.

    Energy Technology Data Exchange (ETDEWEB)

    Raybourn, Elaine Marie; Mendini, Kip (USA JFKSWCS DOTD, Ft. Bragg, NC); Heneghan, Jerry; Deagle, Edwin (USA JFKSWCS DOTD, Ft. Bragg, NC)

    2005-07-01

    Complex problem solving approaches and novel strategies employed by the military at the squad, team, and commander level are often best learned experimentally. Since live action exercises can be costly, advances in simulation game training technology offer exciting ways to enhance current training. Computer games provide an environment for active, critical learning. Games open up possibilities for simultaneous learning on multiple levels; players may learn from contextual information embedded in the dynamics of the game, the organic process generated by the game, and through the risks, benefits, costs, outcomes, and rewards of alternative strategies that result from decision making. In the present paper we discuss a multiplayer computer game simulation created for the Adaptive Thinking & Leadership (ATL) Program to train Special Forces Team Leaders. The ATL training simulation consists of a scripted single-player and an immersive multiplayer environment for classroom use which leverages immersive computer game technology. We define adaptive thinking as consisting of competencies such as negotiation and consensus building skills, the ability to communicate effectively, analyze ambiguous situations, be self-aware, think innovatively, and critically use effective problem solving skills. Each of these competencies is an essential element of leader development training for the U.S. Army Special Forces. The ATL simulation is used to augment experiential learning in the curriculum for the U.S. Army JFK Special Warfare Center & School (SWCS) course in Adaptive Thinking & Leadership. The school is incorporating the ATL simulation game into two additional training pipelines (PSYOPS and Civil Affairs Qualification Courses) that are also concerned with developing cultural awareness, interpersonal communication adaptability, and rapport-building skills. In the present paper, we discuss the design, development, and deployment of the training simulation, and emphasize how the

  3. A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4

    CERN Document Server

    Dickson, Bradley M; Ramjan, Zachary H; Xu, H Eric; Rothbart, Scott B

    2016-01-01

    In this communication we introduce an efficient implementation of adaptive biasing that greatly improves the speed of free energy computation in molecular dynamics simulations. We investigated the use of accelerated simulations to inform on compound design using a recently reported and clinically relevant inhibitor of the chromatin regulator BRD4. Benchmarking on our local compute cluster, our implementation achieves up to 2.5 times more force calls per day than plumed2. Results of five 1{\\mu}second-long simulations are presented, which reveal a conformational switch in the BRD4 inhibitor between a binding competent and incompetent state. Stabilization of the switch led to a -3 kcal/mol improvement of absolute binding free energy. These studies suggest an unexplored ligand design principle and offer new actionable hypotheses for medicinal chemistry efforts against this druggable epigenetic target class.

  4. X-ray absorption spectroscopy and atomic force microscopy study of bias-enhanced nucleation of diamond films

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, M.M.; Jimenez, I.; Vazquez, L.; Gomez-Aleixandre, C.; Albella, J.M.; Sanchez, O. [Instituto de Ciencia de Materiales, C.S.I.C., Cantoblanco28049, Madrid (Spain); Terminello, L.J. [Lawrence Livermore National Laboratory, Livermore, California94551 (United States); Himpsel, F.J. [Department of Physics, University of Wisconsin--Madison, Madison, Wisconsin53706 (United States)

    1998-04-01

    The bias-enhanced nucleation of diamond on Si(100) has been studied by x-ray absorption near-edge spectroscopy (XANES) and atomic force microscopy, two techniques well suited to characterize nanometric crystallites. Diamond nuclei of {approximately}15nm are formed after 5 min of bias-enhanced treatment. The number of nuclei and its size increases with the time of application of the bias voltage. A nanocrystalline diamond film is attained after 20 min of bias-enhanced nucleation. At the initial nucleation stages, the Si substrate appears covered with diamond crystallites and graphite, without SiC being detected by XANES. {copyright} {ital 1998 American Institute of Physics.}

  5. Gravitoinertial force background level affects adaptation to coriolis force perturbations of reaching movements

    Science.gov (United States)

    Lackner, J. R.; Dizio, P.

    1998-01-01

    We evaluated the combined effects on reaching movements of the transient, movement-dependent Coriolis forces and the static centrifugal forces generated in a rotating environment. Specifically, we assessed the effects of comparable Coriolis force perturbations in different static force backgrounds. Two groups of subjects made reaching movements toward a just-extinguished visual target before rotation began, during 10 rpm counterclockwise rotation, and after rotation ceased. One group was seated on the axis of rotation, the other 2.23 m away. The resultant of gravity and centrifugal force on the hand was 1.0 g for the on-center group during 10 rpm rotation, and 1.031 g for the off-center group because of the 0.25 g centrifugal force present. For both groups, rightward Coriolis forces, approximately 0.2 g peak, were generated during voluntary arm movements. The endpoints and paths of the initial per-rotation movements were deviated rightward for both groups by comparable amounts. Within 10 subsequent reaches, the on-center group regained baseline accuracy and straight-line paths; however, even after 40 movements the off-center group had not resumed baseline endpoint accuracy. Mirror-image aftereffects occurred when rotation stopped. These findings demonstrate that manual control is disrupted by transient Coriolis force perturbations and that adaptation can occur even in the absence of visual feedback. An increase, even a small one, in background force level above normal gravity does not affect the size of the reaching errors induced by Coriolis forces nor does it affect the rate of reacquiring straight reaching paths; however, it does hinder restoration of reaching accuracy.

  6. When we should worry more: using cognitive bias modification to drive adaptive health behaviour.

    Science.gov (United States)

    Notebaert, Lies; Chrystal, Jessica; Clarke, Patrick J F; Holmes, Emily A; MacLeod, Colin

    2014-01-01

    A lack of behavioural engagement in health promotion or disease prevention is a problem across many health domains. In these cases where people face a genuine danger, a reduced focus on threat and low levels of anxiety or worry are maladaptive in terms of promoting protection or prevention behaviour. Therefore, it is possible that increasing the processing of threat will increase worry and thereby enhance engagement in adaptive behaviour. Laboratory studies have shown that cognitive bias modification (CBM) can increase or decrease anxiety and worry when increased versus decreased processing of threat is encouraged. In the current study, CBM for interpretation (CBM-I) is used to target engagement in sun protection behaviour. The goal was to investigate whether inducing a negative rather than a positive interpretation bias for physical threat information can enhance worry elicited when viewing a health campaign video (warning against melanoma skin cancer), and consequently lead to more adaptive behaviour (sun protection). Participants were successfully trained to either adopt a positive or negative interpretation bias using physical threat scenarios. However, contrary to expectations results showed that participants in the positive training condition reported higher levels of worry elicited by the melanoma video than participants in the negative training condition. Video elicited worry was, however, positively correlated with a measure of engagement in sun protection behaviour, suggesting that higher levels of worry do promote adaptive behaviour. These findings imply that more research is needed to determine under which conditions increased versus decreased processing of threat can drive adaptive worry. Various potential explanations for the current findings and suggestions for future research are discussed.

  7. When we should worry more: using cognitive bias modification to drive adaptive health behaviour.

    Directory of Open Access Journals (Sweden)

    Lies Notebaert

    Full Text Available A lack of behavioural engagement in health promotion or disease prevention is a problem across many health domains. In these cases where people face a genuine danger, a reduced focus on threat and low levels of anxiety or worry are maladaptive in terms of promoting protection or prevention behaviour. Therefore, it is possible that increasing the processing of threat will increase worry and thereby enhance engagement in adaptive behaviour. Laboratory studies have shown that cognitive bias modification (CBM can increase or decrease anxiety and worry when increased versus decreased processing of threat is encouraged. In the current study, CBM for interpretation (CBM-I is used to target engagement in sun protection behaviour. The goal was to investigate whether inducing a negative rather than a positive interpretation bias for physical threat information can enhance worry elicited when viewing a health campaign video (warning against melanoma skin cancer, and consequently lead to more adaptive behaviour (sun protection. Participants were successfully trained to either adopt a positive or negative interpretation bias using physical threat scenarios. However, contrary to expectations results showed that participants in the positive training condition reported higher levels of worry elicited by the melanoma video than participants in the negative training condition. Video elicited worry was, however, positively correlated with a measure of engagement in sun protection behaviour, suggesting that higher levels of worry do promote adaptive behaviour. These findings imply that more research is needed to determine under which conditions increased versus decreased processing of threat can drive adaptive worry. Various potential explanations for the current findings and suggestions for future research are discussed.

  8. Rapid adaptation to Coriolis force perturbations of arm trajectory.

    Science.gov (United States)

    Lackner, J R; Dizio, P

    1994-07-01

    line to the wrong place. Aftereffects of opposite sign were transiently present in the postrotary movements. 5. These observations fail to support current equilibrium point models, both alpha and lambda, of movement control. Such theories would not predict endpoint errors under our experimental conditions, in which the Coriolis force is absent at the beginning and end of a movement. Our results indicate that detailed aspects of movement trajectory are being continuously monitored on the basis of proprioceptive feedback in relation to motor commands. Adaptive compensations can be initiated after one perturbation despite the absence of either visual or tactile feedback about movement trajectory and endpoint error. Moreover, movement trajectory and end-point can be remapped independently.(ABSTRACT TRUNCATED AT 400 WORDS)

  9. Rapid adaptation to Coriolis force perturbations of arm trajectory

    Science.gov (United States)

    Lackner, J. R.; Dizio, P.

    1994-01-01

    line to the wrong place. Aftereffects of opposite sign were transiently present in the postrotary movements. 5. These observations fail to support current equilibrium point models, both alpha and lambda, of movement control. Such theories would not predict endpoint errors under our experimental conditions, in which the Coriolis force is absent at the beginning and end of a movement. Our results indicate that detailed aspects of movement trajectory are being continuously monitored on the basis of proprioceptive feedback in relation to motor commands. Adaptive compensations can be initiated after one perturbation despite the absence of either visual or tactile feedback about movement trajectory and endpoint error. Moreover, movement trajectory and end-point can be remapped independently.(ABSTRACT TRUNCATED AT 400 WORDS).

  10. Rail-to-rail low-power fully differential OTA utilizing adaptive biasing and partial feedback

    DEFF Research Database (Denmark)

    Tuan Vu, Cao; Wisland, Dag T.; Lande, Tor Sverre;

    consumption. The DC-gain of the proposed OTA is improved by adding a partial feedback loop. A Common-Mode Feedback (CMFB) circuit is required for fully differential rail-to-rail operation. Simulations show that the OTA topology has a low stand-by power consumption of 96μW and a high FoM of 3.84 [(V......A fully differential rail-to-rail Operational Transconductance Amplifier (OTA) with improved DC-gain and reduced power consumption is proposed in this paper. By using the adaptive biasing circuit and two differential inputs, a low stand-by current can be obtained together with reduced power...

  11. Adaptive on-line estimation and control of overlay tool bias

    Science.gov (United States)

    Martinez, Victor M.; Finn, Karen; Edgar, Thomas F.

    2003-06-01

    Modern lithographic manufacturing processes rely on various types of exposure tools, used in a mix-and-match fashion. The motivation to use older tools alongside state-of-the-art tools is lower cost and one of the tradeoffs is a degradation in overlay performance. While average prices of semiconductor products continue to fall, the cost of manufacturing equipment rises with every product generation. Lithography processing, including the cost of ownership for tools, accounts for roughly 30% of the wafer processing costs, thus the importance of mix-and-match strategies. Exponentially Weighted Moving Average (EWMA) run-by-run controllers are widely used in the semiconductor manufacturing industry. This type of controller has been implemented successfully in volume manufacturing, improving Cpk values dramatically in processes like photolithography and chemical mechanical planarization. This simple, but powerful control scheme is well suited for adding corrections to compensate for Overlay Tool Bias (OTB). We have developed an adaptive estimation technique to compensate for overlay variability due to differences in the processing tools. The OTB can be dynamically calculated for each tool, based on the most recent measurements available, and used to correct the control variables. One approach to tracking the effect of different tools is adaptive modeling and control. The basic premise of an adaptive system is to change or adapt the controller as the operating conditions of the system change. Using closed-loop data, the adaptive control algorithm estimates the controller parameters using a recursive estimation technique. Once an updated model of the system is available, modelbased control becomes feasible. In the simplest scenario, the control law can be reformulated to include the current state of the tool (or its estimate) to compensate dynamically for OTB. We have performed simulation studies to predict the impact of deploying this strategy in production. The results

  12. Critically examining language bias in the South African adaptation of the WAIS-III

    Directory of Open Access Journals (Sweden)

    Cheryl D Foxcroft

    2006-04-01

    Full Text Available In response to the growing demand for a test of cognitive ability for South African adults, the Human Sciences Research Council (HSRC adapted the Wechsler Adult Intelligence Scales, third edition (WAIS-III for Englishspeaking South Africans. The standardisation sample included both first and second language English speakers who were either educated largely in English or Afrikaans. The purpose of this article is to critically examine the adaptation process undertaken by the HSRC when standardising the WAIS-III for English-speaking South Africans by deliberating whether sufficient attention was paid to establishing if the measure was equivalent for various groups of English first and second language test-takers. In performing this critical examination, international test adaptation guidelines and standards, psychometric conventions, and national and international research findings were contemplated. The general conclusion reached was that the equivalence of the WAIS-III across diverse language groups has not been unequivocally established and there are indications that some bias may exist for English second language test-takers, especially if they are black or Afrikaans-speaking. Based on these conclusions, recommendations are made regarding the way forward.

  13. Enhancement and bias removal of optical coherence tomography images: An iterative approach with adaptive bilateral filtering.

    Science.gov (United States)

    Sudeep, P V; Issac Niwas, S; Palanisamy, P; Rajan, Jeny; Xiaojun, Yu; Wang, Xianghong; Luo, Yuemei; Liu, Linbo

    2016-04-01

    Optical coherence tomography (OCT) has continually evolved and expanded as one of the most valuable routine tests in ophthalmology. However, noise (speckle) in the acquired images causes quality degradation of OCT images and makes it difficult to analyze the acquired images. In this paper, an iterative approach based on bilateral filtering is proposed for speckle reduction in multiframe OCT data. Gamma noise model is assumed for the observed OCT image. First, the adaptive version of the conventional bilateral filter is applied to enhance the multiframe OCT data and then the bias due to noise is reduced from each of the filtered frames. These unbiased filtered frames are then refined using an iterative approach. Finally, these refined frames are averaged to produce the denoised OCT image. Experimental results on phantom images and real OCT retinal images demonstrate the effectiveness of the proposed filter. PMID:26907572

  14. Application of adaptive kinetic modelling for bias propagation reduction in direct 4D image reconstruction

    Science.gov (United States)

    Kotasidis, F. A.; Matthews, J. C.; Reader, A. J.; Angelis, G. I.; Zaidi, H.

    2014-10-01

    Parametric imaging in thoracic and abdominal PET can provide additional parameters more relevant to the pathophysiology of the system under study. However, dynamic data in the body are noisy due to the limiting counting statistics leading to suboptimal kinetic parameter estimates. Direct 4D image reconstruction algorithms can potentially improve kinetic parameter precision and accuracy in dynamic PET body imaging. However, construction of a common kinetic model is not always feasible and in contrast to post-reconstruction kinetic analysis, errors in poorly modelled regions may spatially propagate to regions which are well modelled. To reduce error propagation from erroneous model fits, we implement and evaluate a new approach to direct parameter estimation by incorporating a recently proposed kinetic modelling strategy within a direct 4D image reconstruction framework. The algorithm uses a secondary more general model to allow a less constrained model fit in regions where the kinetic model does not accurately describe the underlying kinetics. A portion of the residuals then is adaptively included back into the image whilst preserving the primary model characteristics in other well modelled regions using a penalty term that trades off the models. Using fully 4D simulations based on dynamic [15O]H2O datasets, we demonstrate reduction in propagation-related bias for all kinetic parameters. Under noisy conditions, reductions in bias due to propagation are obtained at the cost of increased noise, which in turn results in increased bias and variance of the kinetic parameters. This trade-off reflects the challenge of separating the residuals arising from poor kinetic modelling fits from the residuals arising purely from noise. Nonetheless, the overall root mean square error is reduced in most regions and parameters. Using the adaptive 4D image reconstruction improved model fits can be obtained in poorly modelled regions, leading to reduced errors potentially propagating

  15. Transfer of Assembly Operations to New Workpiece Poses by Adaptation to the Desired Force Profile

    DEFF Research Database (Denmark)

    Nemec, Bojan; Abu-Dakka, Fares; Rytz, Jimmy Alison;

    2013-01-01

    In this paper we propose a new algorithm that can be used for adaptation of robot trajectories in automated assembly tasks. Initial trajectories and forces are obtained by demonstration and iteratively adapted to the specific environment configuration. The algorithm adapts Cartesian space trajector...

  16. Shifting Inductive Bias with Success-Story Algorithm, Adaptive Levin Search, and Incremental Self-Improvement

    NARCIS (Netherlands)

    Schmidhuber, J.; Zhao, J.; Wiering, M.A.

    1997-01-01

    We study task sequences that allow for speeding up the learners average reward intake through appropriate shifts of inductive bias changes of the learner's policy. To evaluate long-term effects of bias shifts setting the stage for later bias shifts we use the "success-story algorithm" (SSA).SSA is

  17. Large-scale analysis of high-speed atomic force microscopy data sets using adaptive image processing

    Directory of Open Access Journals (Sweden)

    Blake W. Erickson

    2012-11-01

    Full Text Available Modern high-speed atomic force microscopes generate significant quantities of data in a short amount of time. Each image in the sequence has to be processed quickly and accurately in order to obtain a true representation of the sample and its changes over time. This paper presents an automated, adaptive algorithm for the required processing of AFM images. The algorithm adaptively corrects for both common one-dimensional distortions as well as the most common two-dimensional distortions. This method uses an iterative thresholded processing algorithm for rapid and accurate separation of background and surface topography. This separation prevents artificial bias from topographic features and ensures the best possible coherence between the different images in a sequence. This method is equally applicable to all channels of AFM data, and can process images in seconds.

  18. Zero-bias autoencoders and the benefits of co-adapting features

    OpenAIRE

    Konda, Kishore; Memisevic, Roland; Krueger, David

    2014-01-01

    Regularized training of an autoencoder typically results in hidden unit biases that take on large negative values. We show that negative biases are a natural result of using a hidden layer whose responsibility is to both represent the input data and act as a selection mechanism that ensures sparsity of the representation. We then show that negative biases impede the learning of data distributions whose intrinsic dimensionality is high. We also propose a new activation function that decouples ...

  19. Hereditary cerebellar ataxia progressively impairs force adaptation during goal-directed arm movements.

    Science.gov (United States)

    Maschke, Matthias; Gomez, Christopher M; Ebner, Timothy J; Konczak, Jürgen

    2004-01-01

    We investigated how humans with hereditary cerebellar degeneration [spinocerebellar ataxia (SCA) type 6 and 8, n = 9] and age- and sex-matched healthy controls (n = 9) adapted goal-directed arm movements to an unknown external force field. We tested whether learning could be generalized to untrained regions in the workspace, an aspect central to the idea of an internal model, and if any learning could be retained. After removal of the force field, SCA patients showed little or no learning-related aftereffects indicating that repeated force-field exposure never led to successful force compensation. In contrast, healthy control subjects quickly adapted their movements to the new force field. The difference in force adaptation was significant for movements to targets that required both the shoulder and elbow joint (P < 0.001). Moreover, the generalization of learned movements to targets outside the learned workspace was prevented by the cerebellar degeneration (P < 0.01). Retention of force adaptation was significantly lower in SCA patients (P = 0.003). The severity of ataxia in SCA patients correlated negatively with the extent of learning (r = -0.84, P = 0.004). Our findings imply that progressive loss of cerebellar function gradually impairs force adaptation. The failure to generalize learning suggests that cerebellar degeneration prevents the formation of an internal representation of the limb dynamics. PMID:13679403

  20. Haiti's adaptation practices to natural forces between 1850-2010

    Science.gov (United States)

    Klose, C. D.

    2011-12-01

    The two Caribbean states, Haiti and the Dominic an Republic, have experienced similar natural forces since the 18th century, such as for instance, hurricanes and earthquakes. Despite this fact, Haiti tends to be more vulnerable to natural forces than the Dominic an Republic, while environmental management strategies have been very different in both countries throughout the 19th and 20th century. Research findings show that neither atmospheric nor seismic hazards, which directly hit the territory of Haiti, have significant impacts on long-term population densities and growth rates. Conversely, migration and urbanization in Haiti between 1850 and 2009 have systematically exposed more people to natural forces, such as tropical storms an floods.

  1. Working memory capacity is associated with optimal adaptation of response bias to perceptual sensitivity in emotion perception.

    Science.gov (United States)

    Lynn, Spencer K; Ibagon, Camila; Bui, Eric; Palitz, Sophie A; Simon, Naomi M; Barrett, Lisa Feldman

    2016-03-01

    Emotion perception, inferring the emotional state of another person, is a frequent judgment made under perceptual uncertainty (e.g., a scowling facial expression can indicate anger or concentration) and behavioral risk (e.g., incorrect judgment can be costly to the perceiver). Working memory capacity (WMC), the ability to maintain controlled processing in the face of competing demands, is an important component of many decisions. We investigated the association of WMC and anger perception in a task in which "angry" and "not angry" categories comprised overlapping ranges of scowl intensity, and correct and incorrect responses earned and lost points, respectively. Participants attempted to earn as many points as they could; adopting an optimal response bias would maximize decision utility. Participants with higher WMC more optimally tuned their anger perception response bias to accommodate their perceptual sensitivity (their ability to discriminate the categories) than did participants with lower WMC. Other factors that influence response bias (i.e., the relative base rate of angry vs. not angry faces and the decision costs and benefits) were ruled out as contributors to the WMC-bias relationship. Our results suggest that WMC optimizes emotion perception by contributing to perceivers' ability to adjust their response bias to account for their level of perceptual sensitivity, likely an important component of adapting emotion perception to dynamic social interactions and changing circumstances. (PsycINFO Database Record

  2. Working memory capacity is associated with optimal adaptation of response bias to perceptual sensitivity in emotion perception.

    Science.gov (United States)

    Lynn, Spencer K; Ibagon, Camila; Bui, Eric; Palitz, Sophie A; Simon, Naomi M; Barrett, Lisa Feldman

    2016-03-01

    Emotion perception, inferring the emotional state of another person, is a frequent judgment made under perceptual uncertainty (e.g., a scowling facial expression can indicate anger or concentration) and behavioral risk (e.g., incorrect judgment can be costly to the perceiver). Working memory capacity (WMC), the ability to maintain controlled processing in the face of competing demands, is an important component of many decisions. We investigated the association of WMC and anger perception in a task in which "angry" and "not angry" categories comprised overlapping ranges of scowl intensity, and correct and incorrect responses earned and lost points, respectively. Participants attempted to earn as many points as they could; adopting an optimal response bias would maximize decision utility. Participants with higher WMC more optimally tuned their anger perception response bias to accommodate their perceptual sensitivity (their ability to discriminate the categories) than did participants with lower WMC. Other factors that influence response bias (i.e., the relative base rate of angry vs. not angry faces and the decision costs and benefits) were ruled out as contributors to the WMC-bias relationship. Our results suggest that WMC optimizes emotion perception by contributing to perceivers' ability to adjust their response bias to account for their level of perceptual sensitivity, likely an important component of adapting emotion perception to dynamic social interactions and changing circumstances. (PsycINFO Database Record PMID:26461251

  3. Method and apparatus for adaptive force and position control of manipulators

    Science.gov (United States)

    Seraji, Homayoun (Inventor)

    1995-01-01

    The described and improved multi-arm invention of this application presents three strategies for adaptive control of cooperative multi-arm robots which coordinate control over a common load. In the position-position control strategy, the adaptive controllers ensure that the end-effector positions of both arms track desired trajectories in Cartesian space despite unknown time-varying interaction forces exerted through a load. In the position-hybrid control strategy, the adaptive controller of one arm controls end-effector motions in the free directions and applied forces in the constraint directions; while the adaptive controller of the other arm ensures that the end-effector tracks desired position trajectories. In the hybrid-hybrid control strategy, the adaptive controllers ensure that both end-effectors track reference position trajectories while simultaneously applying desired forces on the load. In all three control strategies, the cross-coupling effects between the arms are treated as disturbances which are compensated for by the adaptive controllers while following desired commands in a common frame of reference. The adaptive controllers do not require the complex mathematical model of the arm dynamics or any knowledge of the arm dynamic parameters or the load parameters such as mass and stiffness. Circuits in the adaptive feedback and feedforward controllers are varied by novel adaptation laws.

  4. Aging, visual information, and adaptation to task asymmetry in bimanual force coordination.

    Science.gov (United States)

    Hu, Xiaogang; Newell, Karl M

    2011-12-01

    This study investigated the coordination and control strategies that the elderly adopt during a redundant finger force coordination task and how the amount of visual information regulates the coordination patterns. Three age groups (20-24, 65-69, and 75-79 yr) performed a bimanual asymmetric force task. Task asymmetry was manipulated via imposing different coefficients on the finger forces such that the weighted sum of the two index finger forces equaled the total force. The amount of visual information was manipulated by changing the visual information gain of the total force output. Two hypotheses were tested: the reduced adaptability hypothesis predicts that the elderly show less degree of force asymmetry between hands compared with young adults in the asymmetric coefficient conditions, whereas the compensatory hypothesis predicts that the elderly exhibit more asymmetric force coordination patterns with asymmetric coefficients. Under the compensatory hypothesis, two contrasting directions of force sharing strategies (i.e., more efficient coordination strategy and minimum variance strategy) are expected. A deteriorated task performance (high performance error and force variability) was found in the two elderly groups, but enhanced visual information improved the task performance in all age groups. With low visual information gain, the elderly showed reduced adaptability (i.e., less asymmetric forces between hands) to the unequal weighting coefficients, which supported the reduced adaptability hypothesis; however, the elderly revealed the same degree of adaptation as the young group under high visual gain. The findings are consistent with the notion that the age-related reorganization of force coordination and control patterns is mediated by visual information and, more generally, the interactive influence of multiple categories of constraints.

  5. Early and late rate of force development: differential adaptive responses to resistance training?

    DEFF Research Database (Denmark)

    Andersen, L L; Andersen, Jesper Løvind; Zebis, M K;

    2010-01-01

    The objective of this study is to investigate the potentially opposing influence of qualitative and quantitative muscular adaptations in response to high-intensity resistance training on contractile rate of force development (RFD) in the early (200 ms) of rising muscle force. Fifteen healthy young......-intensity resistance training due to differential influences of qualitative and quantitative muscular adaptations on early and later phases of rising muscle force....... males participated in a 14-week resistance training intervention for the lower body and 10 matched subjects participated as controls. Maximal muscle strength (MVC) and RFD were measured during maximal voluntary isometric contraction of the quadriceps femoris muscle. Muscle biopsies were obtained from...

  6. Prediction of contact forces of underactuated finger by adaptive neuro fuzzy approach

    Science.gov (United States)

    Petković, Dalibor; Shamshirband, Shahaboddin; Abbasi, Almas; Kiani, Kourosh; Al-Shammari, Eiman Tamah

    2015-12-01

    To obtain adaptive finger passive underactuation can be used. Underactuation principle can be used to adapt shapes of the fingers for grasping objects. The fingers with underactuation do not require control algorithm. In this study a kinetostatic model of the underactuated finger mechanism was analyzed. The underactuation is achieved by adding the compliance in every finger joint. Since the contact forces of the finger depend on contact position of the finger and object, it is suitable to make a prediction model for the contact forces in function of contact positions of the finger and grasping objects. In this study prediction of the contact forces was established by a soft computing approach. Adaptive neuro-fuzzy inference system (ANFIS) was applied as the soft computing method to perform the prediction of the finger contact forces.

  7. Adaptation to climatic variability and change. Report of the task force on climate adaptation

    International Nuclear Information System (INIS)

    A critique and interpretation is presented of what is known and available about adaptation to climate changes, not based on any particular climate scenario. It is assumed that variability is a fact of climate and that changes in climatic conditions are possible and are constantly occurring. Emphasis is on adaptation with regard to economic and social activities in Canada. A series of linked objectives are addressed, relating to demonstration of the significance of adaptation, consideration of case studies of adaptation (past and potential future) in Canada, clarification of the meaning of adaptation and the forms it takes, assessment of policy implications, and identification of research priorities. The basic facts on global climate change are reviewed, including long-term temperature variations, and adaptation is discussed as a public policy response. Examples of adaptation in Canada are given in the areas of Great Lakes property, power generation, and transportation; Atlantic Canada communities and fisheries; forestry; the construction industry; the energy industry; recreation and tourism; agriculture; urban areas; and national defense. Recommendations regarding adapation are made to governments, the private sector, and researchers. An inventory of adaptation strategies for agriculture, the Arctic, coastal areas, ecosystems and land use, energy supply, fisheries, forestry, urban infrastructure, and water resources is appended

  8. Leadership Adaptation and Traits in Nepalese Police Forces

    Directory of Open Access Journals (Sweden)

    Thakur Mohan Shrestha

    2015-07-01

    Full Text Available Recently, the role of leadership has been considered as one of the crucial factors for the success of any organization. However, what constitutes the effective leaders and what is the status of leaderships is still a subject of study. Hence, this research article is carried out with a mixed method. Based on the evaluation of 7 leadership styles, Bass and Avolio (1994's "5Is" behaviors, 49 traits, and 28 affecting elements for the development of police officers in Nepal, this study has used a survey questionnaire from 1111(N and in-depth interview from 21(N respondents from all the districts of Nepal. The findings of the study display that people are expecting a lot from police administration for adaptation of transformational leadership followed by participative/democratic, authentic and strategic models which were rated with highest ratings respectively. The trait status does not seem sound since the negative traits seem dominant with highest rating-' moderately to mostly', whereas the majority of positive traits are rated with 'a little to moderately'. Moreover, the transformational leadership behaviour is dealt with 'a little to moderately', which needs to be improved.Keywords: Leadership Styles, Leadership Traits, Transformational Behavior, Security Concern Functions of the country

  9. Adaptation of manipulation skills in physical contact with the environment to reference force profiles

    DEFF Research Database (Denmark)

    Abu-Dakka, Fares J.; Nemec, Bojan; Jørgensen, Jimmy A.;

    2015-01-01

    We propose a new methodology for learning and adaption of manipulation skills that involve physical contact with the environment. Pure position control is unsuitable for such tasks because even small errors in the desired trajectory can cause significant deviations from the desired forces...... and torques. The proposed algorithm takes a reference Cartesian trajectory and force/torque profile as input and adapts the movement so that the resulting forces and torques match the reference profiles. The learning algorithm is based on dynamic movement primitives and quaternion representation...... of orientation, which provide a mathematical machinery for efficient and stable adaptation. Experimentally we show that the robot’s performance can be significantly improved within a few iteration steps, compensating for vision and other errors that might arise during the execution of the task. We also show...

  10. How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire.

    Science.gov (United States)

    Blevins, Sydney J; Pierce, Brian G; Singh, Nishant K; Riley, Timothy P; Wang, Yuan; Spear, Timothy T; Nishimura, Michael I; Weng, Zhiping; Baker, Brian M

    2016-03-01

    How T-cell receptors (TCRs) can be intrinsically biased toward MHC proteins while simultaneously display the structural adaptability required to engage diverse ligands remains a controversial puzzle. We addressed this by examining αβ TCR sequences and structures for evidence of physicochemical compatibility with MHC proteins. We found that human TCRs are enriched in the capacity to engage a polymorphic, positively charged "hot-spot" region that is almost exclusive to the α1-helix of the common human class I MHC protein, HLA-A*0201 (HLA-A2). TCR binding necessitates hot-spot burial, yielding high energetic penalties that must be offset via complementary electrostatic interactions. Enrichment of negative charges in TCR binding loops, particularly the germ-line loops encoded by the TCR Vα and Vβ genes, provides this capacity and is correlated with restricted positioning of TCRs over HLA-A2. Notably, this enrichment is absent from antibody genes. The data suggest a built-in TCR compatibility with HLA-A2 that biases receptors toward, but does not compel, particular binding modes. Our findings provide an instructional example for how structurally pliant MHC biases can be encoded within TCRs. PMID:26884163

  11. Weak-lensing shear estimates with general adaptive moments, and studies of bias by pixellation, PSF distortions, and noise

    CERN Document Server

    Simon, Patrick

    2016-01-01

    In weak gravitational lensing, weighted quadrupole moments of the brightness profile in galaxy images are a common way to estimate gravitational shear. We employ general adaptive moments (GLAM) to study causes of shear bias on a fundamental level and for a practical definition of an image ellipticity. For GLAM, the ellipticity is identical to that of isophotes of elliptical images, and this ellipticity is always an unbiased estimator of reduced shear. Our theoretical framework reiterates that moment-based techniques are similar to a model-based approach in the sense that they fit an elliptical profile to the image to obtain weighted moments. As a result, moment-based estimates of ellipticities are prone to underfitting bias. The estimation is fundamentally limited mainly by pixellation which destroys information on the original, pre-seeing image. We give an optimized estimator for the pre-seeing GLAM ellipticity and its bias for noise-free images. To deal with images where pixel noise is prominent, we conside...

  12. Power spectrum analysis with least-squares fitting: Amplitude bias and its elimination, with application to optical tweezers and atomic force microscope cantilevers

    DEFF Research Database (Denmark)

    Nørlykke, Simon F.; Flyvbjerg, Henrik

    2010-01-01

    Optical tweezers and atomic force microscope (AFM) cantilevers are often calibrated by fitting their experimental power spectra of Brownian motion. We demonstrate here that if this is done with typical weighted least-squares methods, the result is a bias of relative size between -2/n and + 1/n...... on the value of the fitted diffusion coefficient. Here, n is the number of power spectra averaged over, so typical calibrations contain 10%-20% bias. Both the sign and the size of the bias depend on the weighting scheme applied. Hence, so do length-scale calibrations based on the diffusion coefficient....... The fitted value for the characteristic frequency is not affected by this bias. For the AFM then, force measurements are not affected provided an independent length-scale calibration is available. For optical tweezers there is no such luck, since the spring constant is found as the ratio...

  13. Generalization of force-field adaptation in proprioceptively-deafferented subjects.

    Science.gov (United States)

    Lefumat, Hannah Z; Miall, R Chris; Cole, Jonathan D; Bringoux, Lionel; Bourdin, Christophe; Vercher, Jean-Louis; Sarlegna, Fabrice R

    2016-03-11

    Humans have the remarkable ability to adapt their motor behaviour to changes in body properties and/or environmental conditions, based on sensory feedback such as vision and proprioception. The role of proprioception has been highlighted for the adaptation to new upper-limb dynamics, which is known to generalize to the opposite, non-adapted limb in healthy individuals. Such interlimb transfer seems to depend on sensory feedback, and the present study assessed whether the chronic loss of proprioception precludes interlimb transfer of dynamic adaptation by testing two well-characterized proprioceptively-deafferented subjects. These had to reach toward visual targets with vision of the limb. For both deafferented subjects, we observed adaptation of the dominant arm to Coriolis forces and after-effects on non-dominant arm movements in different movement directions, thus indicating interlimb transfer. Overall, our findings show that motor learning can generalize across limbs and movement directions despite the loss of proprioceptive afferents.

  14. Next-Generation Force Fields from Symmetry-Adapted Perturbation Theory

    Science.gov (United States)

    McDaniel, Jesse G.; Schmidt, J. R.

    2016-05-01

    Symmetry-adapted perturbation theory (SAPT) provides a unique set of advantages for parameterizing next-generation force fields from first principles. SAPT provides a direct, basis-set superposition error free estimate of molecular interaction energies, a physically intuitive energy decomposition, and a seamless transition to an asymptotic picture of intermolecular interactions. These properties have been exploited throughout the literature to develop next-generation force fields for a variety of applications, including classical molecular dynamics simulations, crystal structure prediction, and quantum dynamics/spectroscopy. This review provides a brief overview of the formalism and theory of SAPT, along with a practical discussion of the various methodologies utilized to parameterize force fields from SAPT calculations. It also highlights a number of applications of SAPT-based force fields for chemical systems of particular interest. Finally, the review ends with a brief outlook on the future opportunities and challenges that remain for next-generation force fields based on SAPT.

  15. Active and Adaptive Learning from Biased Data with Applications in Astronomy

    DEFF Research Database (Denmark)

    Kremer, Jan

    with low-dimensional feature spaces: a common setting in astronomical applications such as photometric redshift estimation. Another form of bias stems from label noise. This thesis considers the scenario in which unreliable labels can be replaced by highly accurate labels at a certain cost. This is......, for example, the case in crowd-sourcing, where unreliable labelers can be corrected by experts, or in astronomy, where a labeling based on photometric data can be improved by spectroscopic observations. An algorithm to actively select objects for correction under a limited re-labeling budget is presented...

  16. Motor adaptation to Coriolis force perturbations of reaching movements: endpoint but not trajectory adaptation transfers to the nonexposed arm

    Science.gov (United States)

    Dizio, P.; Lackner, J. R.

    1995-01-01

    1. Reaching movements made in a rotating room generate Coriolis forces that are directly proportional to the cross product of the room's angular velocity and the arm's linear velocity. Such Coriolis forces are inertial forces not involving mechanical contact with the arm. 2. We measured the trajectories of arm movements made in darkness to a visual target that was extinguished at the onset of each reach. Prerotation subjects pointed with both the right and left arms in alternating sets of eight movements. During rotation at 10 rpm, the subjects reached only with the right arm. Postrotation, the subjects pointed with the left and right arms, starting with the left, in alternating sets of eight movements. 3. The initial perrotary reaching movements of the right arm were highly deviated both in movement path and endpoint relative to the prerotation reaches of the right arm. With additional movements, subjects rapidly regained straight movement paths and accurate endpoints despite the absence of visual or tactile feedback about reaching accuracy. The initial postrotation reaches of the left arm followed straight paths to the wrong endpoint. The initial postrotation reaches of the right arm had paths with mirror image curvature to the initial perrotation reaches of the right arm but went to the correct endpoint. 4. These observations are inconsistent with current equilibrium point models of movement control. Such theories predict accurate reaches under our experimental conditions. Our observations further show independent implementation of movement and posture, as evidenced by transfer of endpoint adaptation to the nonexposed arm without transfer of path adaptation. Endpoint control may occur at a relatively central stage that represents general constraints such as gravitoinertial force background or egocentric direction relative to both arms, and control of path may occur at a more peripheral stage that represents moments of inertia and muscle dynamics unique to each

  17. Modeling and adaptive motion/force tracking for ver tical wheel on rotating table

    Institute of Scientific and Technical Information of China (English)

    Zhongcai Zhang; Yuqiang Wu; Wei Sun

    2015-01-01

    This paper is devoted to the problem of modeling and adaptive motion/force tracking for a class of nonholonomic dy-namic systems with affine constraints (NDSAC): a vertical wheel on a rotating table. Prior to the development of tracking control er, the dynamic model of the wheel in question is derived in a meticu-lous manner. A continuously differentiable friction model is also considered in the modeling. By exploiting the inherent cascade interconnected structure of the wheel dynamics, an adaptive mo-tion/force tracking control er is presented guaranteeing that the trajectory tracking errors asymptotical y converge to zero while the contact force tracking errors can be made smal enough by tuning design parameters. Simulation results are provided to validate the effectiveness of the proposed tracking methodology.

  18. The influence of catch trials on the consolidation of motor memory in force field adaptation tasks

    Directory of Open Access Journals (Sweden)

    Anne eFocke

    2013-07-01

    Full Text Available In computational neuroscience it is generally accepted that human motor memory contains neural representations of the physics of the musculoskeletal system and the objects in the environment. These representations are called internal models. Force field studies, in which subjects have to adapt to dynamic perturbations induced by a robotic manipulandum, are an established tool to analyze the characteristics of such internal models. The aim of the current study was to investigate whether catch trials during force field learning could influence the consolidation of motor memory in more complex tasks. Thereby, the force field was more than double the force field of previous studies (35 Ns/m. Moreover, the arm of the subjects was not supported. A total of forty-six subjects participated in this study and performed center-out movements at a robotic manipulandum in two different force fields. Two control groups learned force field A on day 1 and were retested in the same force field on day 3 (AA. Two test groups additionally learned an interfering force field B (=-A on day 2 (ABA. The difference between the two test and control groups, respectively, was the absence (0% or presence (19% of catch trials, in which the force field was turned off suddenly. The results showed consolidation of force field A on day 3 for both control groups. Test groups showed no consolidation of force field A (19% catch trials and even poorer performance on day 3 (0% catch trials. In conclusion, it can be stated that catch trials seem to have a positive effect on the performance on day 3 but do not trigger a consolidation process as shown in previous studies that used a lower force field viscosity with supported arm. These findings indicate that the results of previous studies in which less complex tasks were analyzed, cannot be fully transferred to more complex tasks. Moreover, the effects of catch trials in these situations are insufficiently understood and further research

  19. ADAPTIVE CONTROLLER AND ITS APPLICATION IN FORCE SYSTEM OF ASYMMETRIC CYLINDER CONTROLLED BY SYMMETRIC VALVE

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Partial pressure, system vibration and asymmetric system dynamic performance exit in asymmetric cylinder controller by symmetric valve hydraulic system. To solve this problem in the force control system, model reference adaptive controller is designed using equilibrium point stability theory and output error equation polynomial. The reference model is selected in such a way that it meets the system dynamic performance. Hardware configuration of asymmetric cylinder controlled by asymmetric valve hydraulic system is replaced by intelligent control algorithm, thus the cost is lowered and easy to application. Simulation results demonstrate that the proposed adaptive control sheme has good adaptive ability and well solves asymmetric dynamic performance problem. The designed adaptive controller is fairly robust to load disturbance and system parameter variation.

  20. On the transferability of three water models developed by adaptive force matching

    CERN Document Server

    Hu, Hongyi; Wang, Feng

    2015-01-01

    Water is perhaps the most simulated liquid. Recently three water models have been developed following the adaptive force matching (AFM) method that provides excellent predictions of water properties with only electronic structure information as a reference. Compared to many other electronic structure based force fields that rely on fairly sophisticated energy expressions, the AFM water models use point-charge based energy expressions that are supported by most popular molecular dynamics packages. An outstanding question regarding simple force fields is whether such force fields provide reasonable transferability outside of their conditions of parameterization. A survey of three AFM water models, B3LYPD-4F, BLYPSP-4F, and WAIL are provided for simulations under conditions ranging from the melting point up to the critical point. By including ice-Ih configurations in the training set, the WAIL potential predicts the melting temperate, TM, of ice-Ih correctly. Without training for ice, BLYPSP-4F underestimates TM...

  1. Nano watt power rail-to-rail CMOS amplifier with adaptive biasing circuits for ultralow-power analog LSIs

    Science.gov (United States)

    Ozaki, Toshihiro; Hirose, Tetsuya; Tsubaki, Keishi; Kuroki, Nobutaka; Numa, Masahiro

    2015-04-01

    In this paper, we present a rail-to-rail folded-cascode amplifier (AMP) with adaptive biasing circuits (ABCs). The circuit uses a nano ampere current reference circuit to achieve ultralow-power and ABCs to achieve high-speed operation. The ABCs are based on conventional circuits and modified to be suitable for rail-to-rail operation. The measurement results demonstrated that the AMP with the proposed ABCs can operate with an ultralow-power of 384 nA when the input voltage was 0.9 V and achieve high speeds of 0.162 V/µs at the rise time and 0.233 V/µs at the fall time when the input pulse frequency and the amplitude were 10 kHz and 1.5 Vpp, respectively.

  2. Line-of-Sight Path Following for Dubins Paths with Adaptive Sideslip Compensation of Drift Forces

    DEFF Research Database (Denmark)

    Fossen, Thor Inge; Pettersen, Kristin Ytterstad; Galeazzi, Roberto

    2015-01-01

    guidance law is intended for maneuvering in the horizontal-plane at given speeds and typical applications are marine craft, autonomous underwater vehicles (AUVs), unmanned aerial vehicles (UAVs) as well as other vehicles and craft where the goal is to follow a predefined parametrized curve without time......We present a nonlinear adaptive path-following controller that compensates for drift forces through vehicle sideslip. Vehicle sideslip arises during path following when the vehicle is subject to drift forces caused by ocean currents, wind and waves. The proposed algorithm is motivated by a lineof...... constraints. Two vehicle cases studies are included to verify the theoretical results....

  3. Immobility in the forced swim test is adaptive and does not reflect depression.

    Science.gov (United States)

    Molendijk, Marc L; de Kloet, E Ronald

    2015-12-01

    The forced swim test is based on the progressive immobility a rodent displays when immersed in a beaker filled with water from where no escape is possible. While the test was originally designed to identify the antidepressant potential of drugs, over the past decade a rapidly growing number of publications (more than 2000) portray this immobility response anthropomorphically as a measure for depression and despair. This is incorrect. The response to the forced swim stressor should be considered for what it shows: a switch from active to passive behavior in the face of an acute stressor, aligned to cognitive functions underlying behavioral adaptation and survival.

  4. Trial-by-Trial Adaptation of Movements during Mental Practice under Force Field

    Directory of Open Access Journals (Sweden)

    Muhammad Nabeel Anwar

    2013-01-01

    Full Text Available Human nervous system tries to minimize the effect of any external perturbing force by bringing modifications in the internal model. These modifications affect the subsequent motor commands generated by the nervous system. Adaptive compensation along with the appropriate modifications of internal model helps in reducing human movement errors. In the current study, we studied how motor imagery influences trial-to-trial learning in a robot-based adaptation task. Two groups of subjects performed reaching movements with or without motor imagery in a velocity-dependent force field. The results show that reaching movements performed with motor imagery have relatively a more focused generalization pattern and a higher learning rate in training direction.

  5. Damping Force Tracking Control of MR Damper System Using a New Direct Adaptive Fuzzy Controller

    Directory of Open Access Journals (Sweden)

    Xuan Phu Do

    2015-01-01

    Full Text Available This paper presents a new direct adaptive fuzzy controller and its effectiveness is verified by investigating the damping force tracking control of magnetorheological (MR fluid based damper (MR damper in short system. In the formulation of the proposed controller, a model of interval type 2 fuzzy controller is combined with the direct adaptive control to achieve high performance in vibration control. In addition, H∞ (H infinity tracking technique is used in building a model of the direct adaptive fuzzy controller in which an enhanced iterative algorithm is combined with the fuzzy model. After establishing a closed-loop control structure to achieve high control performance, a cylindrical MR damper is adopted and damping force tracking results are obtained and discussed. In addition, in order to demonstrate the effectiveness of the proposed control strategy, two existing controllers are modified and tested for comparative work. It has been demonstrated from simulation and experiment that the proposed control scheme provides much better control performance in terms of damping force tracking error. This leads to excellent vibration control performance of the semiactive MR damper system associated with the proposed controller.

  6. Adaptive GPU-accelerated force calculation for interactive rigid molecular docking using haptics.

    Science.gov (United States)

    Iakovou, Georgios; Hayward, Steven; Laycock, Stephen D

    2015-09-01

    Molecular docking systems model and simulate in silico the interactions of intermolecular binding. Haptics-assisted docking enables the user to interact with the simulation via their sense of touch but a stringent time constraint on the computation of forces is imposed due to the sensitivity of the human haptic system. To simulate high fidelity smooth and stable feedback the haptic feedback loop should run at rates of 500Hz to 1kHz. We present an adaptive force calculation approach that can be executed in parallel on a wide range of Graphics Processing Units (GPUs) for interactive haptics-assisted docking with wider applicability to molecular simulations. Prior to the interactive session either a regular grid or an octree is selected according to the available GPU memory to determine the set of interatomic interactions within a cutoff distance. The total force is then calculated from this set. The approach can achieve force updates in less than 2ms for molecular structures comprising hundreds of thousands of atoms each, with performance improvements of up to 90 times the speed of current CPU-based force calculation approaches used in interactive docking. Furthermore, it overcomes several computational limitations of previous approaches such as pre-computed force grids, and could potentially be used to model receptor flexibility at haptic refresh rates.

  7. The Truth and Bias Model of Judgment

    Science.gov (United States)

    West, Tessa V.; Kenny, David A.

    2011-01-01

    We present a new model for the general study of how the truth and biases affect human judgment. In the truth and bias model, judgments about the world are pulled by 2 primary forces, the truth force and the bias force, and these 2 forces are interrelated. The truth and bias model differentiates force and value, where the force is the strength of…

  8. Increasing Time-Efficiency and Accuracy of Robotic Machining Processes Using Model-Based Adaptive Force Control

    OpenAIRE

    Sörnmo, Olof; Olofsson, Björn; Robertsson, Anders; Johansson, Rolf

    2012-01-01

    Machining processes in the industry of today are rarely performed using industrial robots. In the cases where robots are used, machining is often performed using position control with a conservative feed-rate, to avoid excessive process forces. There is a great benefit in controlling the process forces instead, so as to improve the time-efficiency by applying the maximum allowed force, and thus removing the maximum amount of material per time unit. This paper presents a novel adaptive force c...

  9. Congenitally blind individuals rapidly adapt to coriolis force perturbations of their reaching movements

    Science.gov (United States)

    DiZio, P.; Lackner, J. R.

    2000-01-01

    Reaching movements made to visual targets in a rotating room are initially deviated in path and endpoint in the direction of transient Coriolis forces generated by the motion of the arm relative to the rotating environment. With additional reaches, movements become progressively straighter and more accurate. Such adaptation can occur even in the absence of visual feedback about movement progression or terminus. Here we examined whether congenitally blind and sighted subjects without visual feedback would demonstrate adaptation to Coriolis forces when they pointed to a haptically specified target location. Subjects were tested pre-, per-, and postrotation at 10 rpm counterclockwise. Reaching to straight ahead targets prerotation, both groups exhibited slightly curved paths. Per-rotation, both groups showed large initial deviations of movement path and curvature but within 12 reaches on average had returned to prerotation curvature levels and endpoints. Postrotation, both groups showed mirror image patterns of curvature and endpoint to the per-rotation pattern. The groups did not differ significantly on any of the performance measures. These results provide compelling evidence that motor adaptation to Coriolis perturbations can be achieved on the basis of proprioceptive, somatosensory, and motor information in the complete absence of visual experience.

  10. Reliability and consistency of plantarflexor stretch-shortening cycle function using an adapted force sledge apparatus

    International Nuclear Information System (INIS)

    There are various limitations to existing methods of studying plantarflexor stretch-shortening cycle (SSC) function and muscle-tendon unit (MTU) mechanics, predominantly related to measurement validity and reliability. This study utilizes an innovative adaptation to a force sledge which isolates the plantarflexors and ankle for analysis. The aim of this study was to determine the sledge loading protocol to be used, most appropriate method of data analysis and measurement reliability in a group of healthy, non-injured subjects. Twenty subjects (11 males, 9 females; age: 23.5 ±2.3 years; height: 1.73 ±0.08 m; mass: 74.2 ±11.3 kg) completed 11 impacts at five different loadings rated on a scale of perceived exertion from 1 to 5, where 5 is a loading that the subject could only complete the 11 impacts using the adapted sledge. Analysis of impacts 4–8 or 5–7 using loading 2 provided consistent results that were highly reliable (single intra-class correlation, ICC > 0.85, average ICC > 0.95) and replicated kinematics found in hopping and running. Results support use of an adapted force sledge apparatus as an ecologically valid, reliable method of investigating plantarflexor SSC function and MTU mechanics in a dynamic controlled environment. (paper)

  11. Visual feedback of the moving arm allows complete adaptation of pointing movements to centrifugal and Coriolis forces in human subjects.

    Science.gov (United States)

    Bourdin, C; Gauthier, G; Blouin, J; Vercher, J L

    2001-03-23

    A classical visuo-manual adaptation protocol carried out on a rotating platform was used to test the ability of subjects to adapt to centrifugal and Coriolis forces when visual feedback of the arm is manipulated. Three main results emerge: (a) an early modification of the initial trajectory of the movements takes place even without visual feedback of the arm; (b) despite the change in the initial trajectory, the new external force decreases the accuracy of the pointing movements when vision is precluded; (c) a visual adaptive phase allows complete adaptation of the pointing movements performed in a modified gravitoinertial field. Therefore vision would be essential for subjects to completely adapt to centrifugal and Coriolis forces. However, other sensory signals (i.e. vestibular and proprioceptive) may constitute the basis for early but partial correction of the pointing movements.

  12. Micro-force compensation in automated micro-object positioning using adaptive neural networks

    Science.gov (United States)

    Shahini, M.; Melek, W. W.; Yeow, J. T. W.

    2009-09-01

    This paper proposes a novel approach for controlled pushing of a micro-sized object along a desired path. Challenges associated with this control task due to the presence of dominating micro-forces are carefully studied and a solution based on the application of artificial neural networks is introduced. A nonlinear controller is proposed for controlled pushing of micro-objects which guarantees the stability of the closed-loop system in the Lyapunov sense. An experimental setup is designed to validate the performance of the proposed controller. Results suggest that artificial neural networks present a promising tool for design of adaptive controllers to accurately manipulate objects in the microscopic scale.

  13. Adaptive method for real-time gait phase detection based on ground contact forces.

    Science.gov (United States)

    Yu, Lie; Zheng, Jianbin; Wang, Yang; Song, Zhengge; Zhan, Enqi

    2015-01-01

    A novel method is presented to detect real-time gait phases based on ground contact forces (GCFs) measured by force sensitive resistors (FSRs). The traditional threshold method (TM) sets a threshold to divide the GCFs into on-ground and off-ground statuses. However, TM is neither an adaptive nor real-time method. The threshold setting is based on body weight or the maximum and minimum GCFs in the gait cycles, resulting in different thresholds needed for different walking conditions. Additionally, the maximum and minimum GCFs are only obtainable after data processing. Therefore, this paper proposes a proportion method (PM) that calculates the sums and proportions of GCFs wherein the GCFs are obtained from FSRs. A gait analysis is then implemented by the proposed gait phase detection algorithm (GPDA). Finally, the PM reliability is determined by comparing the detection results between PM and TM. Experimental results demonstrate that the proposed PM is highly reliable in all walking conditions. In addition, PM could be utilized to analyze gait phases in real time. Finally, PM exhibits strong adaptability to different walking conditions.

  14. Adaptive force produced by stress-induced regulation of random variation intensity.

    Science.gov (United States)

    Shimansky, Yury P

    2010-08-01

    The Darwinian theory of life evolution is capable of explaining the majority of related phenomena. At the same time, the mechanisms of optimizing traits beneficial to a population as a whole but not directly to an individual remain largely unclear. There are also significant problems with explaining the phenomenon of punctuated equilibrium. From another perspective, multiple mechanisms for the regulation of the rate of genetic mutations according to the environmental stress have been discovered, but their precise functional role is not well understood yet. Here a novel mathematical paradigm called a Kinetic-Force Principle (KFP), which can serve as a general basis for biologically plausible optimization methods, is introduced and its rigorous derivation is provided. Based on this principle, it is shown that, if the rate of random changes in a biological system is proportional, even only roughly, to the amount of environmental stress, a virtual force is created, acting in the direction of stress relief. It is demonstrated that KFP can provide important insights into solving the above problems. Evidence is presented in support of a hypothesis that the nature employs KFP for accelerating adaptation in biological systems. A detailed comparison between KFP and the principle of variation and natural selection is presented and their complementarity is revealed. It is concluded that KFP is not a competing alternative, but a powerful addition to the principle of variation and natural selection. It is also shown KFP can be used in multiple ways for adaptation of individual biological organisms. PMID:20361203

  15. Evolutionary force in confamiliar marine vertebrates of different temperature realms: adaptive trends in zoarcid fish transcriptomes

    Directory of Open Access Journals (Sweden)

    Windisch Heidrun Sigrid

    2012-10-01

    Full Text Available Abstract Background Studies of temperature-induced adaptation on the basis of genomic sequence data were mainly done in extremophiles. Although the general hypothesis of an increased molecular flexibility in the cold is widely accepted, the results of thermal adaptation are still difficult to detect at proteomic down to the genomic sequence level. Approaches towards a more detailed picture emerge with the advent of new sequencing technologies. Only small changes in primary protein structure have been shown to modify kinetic and thermal properties of enzymes, but likewise for interspecies comparisons a high genetic identity is still essential to specify common principles. The present study uses comprehensive transcriptomic sequence information to uncover general patterns of thermal adaptation on the RNA as well as protein primary structure. Results By comparing orthologous sequences of two closely related zoarcid fish inhabiting different latitudinal zones (Antarctica: Pachycara brachycephalum, temperate zone: Zoarces viviparus we were able to detect significant differences in the codon usage. In the cold-adapted species a lower GC content in the wobble position prevailed for preserved amino acids. We were able to estimate 40-60% coverage of the functions represented within the two compared zoarcid cDNA-libraries on the basis of a reference genome of the phylogenetically closely related fish Gasterosteus aculeatus. A distinct pattern of amino acid substitutions could be identified for the non-synonymous codon exchanges, with a remarkable surplus of serine and reduction of glutamic acid and asparagine for the Antarctic species. Conclusion Based on the differences between orthologous sequences from confamiliar species, distinguished mainly by the temperature regimes of their habitats, we hypothesize that temperature leaves a signature on the composition of biological macromolecules (RNA, proteins with implications for the transcription and

  16. Influence of certain forces on evolution of synonymous codon usage bias in certain species of three basal orders of aquatic insects.

    Science.gov (United States)

    Selva Kumar, C; Nair, Rahul R; Sivaramakrishnan, K G; Ganesh, D; Janarthanan, S; Arunachalam, M; Sivaruban, T

    2012-12-01

    Forces that influence the evolution of synonymous codon usage bias are analyzed in six species of three basal orders of aquatic insects. The rationale behind choosing six species of aquatic insects (three from Ephemeroptera, one from Plecoptera, and two from Odonata) for the present analysis is based on phylogenetic position at the basal clades of the Order Insecta facilitating the understanding of the evolution of codon bias and of factors shaping codon usage patterns in primitive clades of insect lineages and their subtle differences in some of their ecological and environmental requirements in terms of habitat-microhabitat requirements, altitudinal preferences, temperature tolerance ranges, and consequent responses to climate change impacts. The present analysis focuses on open reading frames of the 13 protein-coding genes in the mitochondrial genome of six carefully chosen insect species to get a comprehensive picture of the evolutionary intricacies of codon bias. In all the six species, A and T contents are observed to be significantly higher than G and C, and are used roughly equally. Since transcription hypothesis on codon usage demands A richness and T poorness, it is quite likely that mutation pressure may be the key factor associated with synonymous codon usage (SCU) variations in these species because the mutation hypothesis predicts AT richness and GC poorness in the mitochondrial DNA. Thus, AT-biased mutation pressure seems to be an important factor in framing the SCU variation in all the selected species of aquatic insects, which in turn explains the predominance of A and T ending codons in these species. This study does not find any association between microhabitats and codon usage variations in the mitochondria of selected aquatic insects. However, this study has identified major forces, such as compositional constraints and mutation pressure, which shape patterns of codon usage in mitochondrial genes in the primitive clades of insect lineages. PMID

  17. Adaptation to Coriolis force perturbation of movement trajectory; role of proprioceptive and cutaneous somatosensory feedback.

    Science.gov (United States)

    Lackner, James R; DiZio, Paul

    2002-01-01

    Subjects exposed to constant velocity rotation in a large fully-enclosed room that rotates initially make large reaching errors in pointing to targets. The paths and endpoints of their reaches are deviated in the direction of the transient lateral Coriolis forces generated by the forward velocity of their reaches. With additional reaches, subjects soon reach in straighter paths and become more accurate at landing on target even in the absence of visual feedback about their movements. Two factors contribute to this adaptation: first, muscle spindle and golgi tendon organ feedback interpreted in relation to efferent commands provide information about movement trajectory, and second, somatosensory stimulation of the fingertip at the completion of a reach provides information about the location of the fingertip relative to the torso.

  18. Adaptation to Coriolis force perturbation of movement trajectory; role of proprioceptive and cutaneous somatosensory feedback

    Science.gov (United States)

    Lackner, James R.; DiZio, Paul

    2002-01-01

    Subjects exposed to constant velocity rotation in a large fully-enclosed room that rotates initially make large reaching errors in pointing to targets. The paths and endpoints of their reaches are deviated in the direction of the transient lateral Coriolis forces generated by the forward velocity of their reaches. With additional reaches, subjects soon reach in straighter paths and become more accurate at landing on target even in the absence of visual feedback about their movements. Two factors contribute to this adaptation: first, muscle spindle and golgi tendon organ feedback interpreted in relation to efferent commands provide information about movement trajectory, and second, somatosensory stimulation of the fingertip at the completion of a reach provides information about the location of the fingertip relative to the torso.

  19. High-end climate change impact on European runoff and low flows - exploring the effects of forcing biases

    Science.gov (United States)

    Papadimitriou, Lamprini V.; Koutroulis, Aristeidis G.; Grillakis, Manolis G.; Tsanis, Ioannis K.

    2016-05-01

    Climate models project a much more substantial warming than the 2 °C target under the more probable emission scenarios, making higher-end scenarios increasingly plausible. Freshwater availability under such conditions is a key issue of concern. In this study, an ensemble of Euro-CORDEX projections under RCP8.5 is used to assess the mean and low hydrological states under +4 °C of global warming for the European region. Five major European catchments were analysed in terms of future drought climatology and the impact of +2 °C versus +4 °C global warming was investigated. The effect of bias correction of the climate model outputs and the observations used for this adjustment was also quantified. Projections indicate an intensification of the water cycle at higher levels of warming. Even for areas where the average state may not considerably be affected, low flows are expected to reduce, leading to changes in the number of dry days and thus drought climatology. The identified increasing or decreasing runoff trends are substantially intensified when moving from the +2 to the +4° of global warming. Bias correction resulted in an improved representation of the historical hydrology. It is also found that the selection of the observational data set for the application of the bias correction has an impact on the projected signal that could be of the same order of magnitude to the selection of the Global Climate Model (GCM).

  20. Adaptive-backstepping force/motion control for mobile-manipulator robot based on fuzzy CMAC neural networks

    Institute of Scientific and Technical Information of China (English)

    Thang-Long MAI; Yaonan WANG

    2014-01-01

    In this paper, an adaptive backstepping fuzzy cerebellar-model-articulation-control neural-networks control (ABFCNC) system for motion/force control of the mobile-manipulator robot (MMR) is proposed. By applying the ABFCNC in the tracking-position controller, the unknown dynamics and parameter variation problems of the MMR control system are relaxed. In addition, an adaptive robust compensator is proposed to eliminate uncertainties that consist of approximation errors, uncertain disturbances. Based on the tracking position-ABFCNC design, an adaptive robust control strategy is also developed for the nonholonomic-constraint force of the MMR. The design of adaptive-online learning algorithms is obtained by using the Lyapunov stability theorem. Therefore, the proposed method proves that it not only can guarantee the stability and robustness but also the tracking performances of the MMR control system. The effectiveness and robustness of the proposed control system are verified by comparative simulation results.

  1. Adaptive locomotor training on an end-effector gait robot: evaluation of the ground reaction forces in different training conditions.

    Science.gov (United States)

    Tomelleri, Christopher; Waldner, Andreas; Werner, Cordula; Hesse, Stefan

    2011-01-01

    The main goal of robotic gait rehabilitation is the restoration of independent gait. To achieve this goal different and specific patterns have to be practiced intensively in order to stimulate the learning process of the central nervous system. The gait robot G-EO Systems was designed to allow the repetitive practice of floor walking, stair climbing and stair descending. A novel control strategy allows training in adaptive mode. The force interactions between the foot and the ground were analyzed on 8 healthy volunteers in three different conditions: real floor walking on a treadmill, floor walking on the gait robot in passive mode, floor walking on the gait robot in adaptive mode. The ground reaction forces were measured by a Computer Dyno Graphy (CDG) analysis system. The results show different intensities of the ground reaction force across all of the three conditions. The intensities of force interactions during the adaptive training mode are comparable to the real walking on the treadmill. Slight deviations still occur in regard to the timing pattern of the forces. The adaptive control strategy comes closer to the physiological swing phase than the passive mode and seems to be a promising option for the treatment of gait disorders. Clinical trials will validate the efficacy of this new option in locomotor therapy on the patients.

  2. Dynamic modeling of slow-light in a semiconductor optical amplifier including the effects of forced coherent population oscillations by bias current modulation

    Science.gov (United States)

    Connelly, M. J.

    2014-05-01

    The slow light effect in SOAs has many applications in microwave photonics such as phase shifting and filtering. Models are needed to predict slow light in SOAs and its dependence on the bias current, optical power and modulation index. In this paper we predict the slow light characteristics of a tensile-strained SOA by using a detailed time-domain model. The model includes full band-structure based calculations of the material gain, bimolecular recombination and spontaneous emission, a carrier density rate equation and travelling wave equations for the input signal and amplified spontaneous emission. The slow light effect is caused by coherent population oscillations, whereby beating between the spectral components of an amplitude modulated lightwave causes carrier density oscillations at the beat frequency, leading to changes in the group velocity. The resulting beat signal at the SOA output after photodetection, is phase shifted relative to the SOA input beat signal. The phase shift can be adjusted by controlling the optical power and bias current. However the beat signal gain is low at low frequencies, leading to a poor beat signal output signal-to-noise ratio. If the optical input and SOA drive current are simultaneously modulated, this leads to forced population oscillations that greatly enhance the low frequency beat signal gain. The model is used to determine the improvement in gain and phase response and its dependency on the optical power, bias current and modulation index. Model predictions show good agreement with experimental trends reported in the literature.

  3. The Adaptive Buffered Force QM/MM method in the CP2K and AMBER software packages

    CERN Document Server

    Mones, Letif; Götz, Andreas W; Laino, Teodoro; Walker, Ross C; Leimkuhler, Ben; Csányi, Gábor; Bernstein, Noam

    2014-01-01

    The implementation and validation of the adaptive buffered force QM/MM method in two popular packages, CP2K and AMBER are presented. The implementations build on the existing QM/MM functionality in each code, extending it to allow for redefinition of the QM and MM regions during the simulation and reducing QM-MM interface errors by discarding forces near the boundary according to the buffered force-mixing approach. New adaptive thermostats, needed by force-mixing methods, are also implemented. Different variants of the method are benchmarked by simulating the structure of bulk water, water autoprotolysis in the presence of zinc and dimethyl-phosphate hydrolysis using various semiempirical Hamiltonians and density functional theory as the QM model. It is shown that with suitable parameters, based on force convergence tests, the adaptive buffered-force QM/MM scheme can provide an accurate approximation of the structure in the dynamical QM region matching the corresponding fully QM simulations, as well as reprod...

  4. Force-Field Induced Bias in the Structure of Aβ21-30: A Comparison of OPLS, AMBER, CHARMM, and GROMOS Force Fields.

    Science.gov (United States)

    Smith, Micholas Dean; Rao, J Srinivasa; Segelken, Elizabeth; Cruz, Luis

    2015-12-28

    In this work we examine the dynamics of an intrinsically disordered protein fragment of the amyloid β, the Aβ21-30, under seven commonly used molecular dynamics force fields (OPLS-AA, CHARMM27-CMAP, AMBER99, AMBER99SB, AMBER99SB-ILDN, AMBER03, and GROMOS53A6), and three water models (TIP3P, TIP4P, and SPC/E). We find that the tested force fields and water models have little effect on the measures of radii of gyration and solvent accessible surface area (SASA); however, secondary structure measures and intrapeptide hydrogen-bonding are significantly modified, with AMBER (99, 99SB, 99SB-ILDN, and 03) and CHARMM22/27 force-fields readily increasing helical content and the variety of intrapeptide hydrogen bonds. On the basis of a comparison between the population of helical and β structures found in experiments, our data suggest that force fields that suppress the formation of helical structure might be a better choice to model the Aβ21-30 peptide. PMID:26629886

  5. Adaptive Nonlinear Tire-Road Friction Force Estimation for Vehicular Systems Based on a Novel Differentiable Friction Model

    Directory of Open Access Journals (Sweden)

    Zhi-Jun Fu

    2015-01-01

    Full Text Available A novel adaptive nonlinear observer-based parameter estimation scheme using a newly continuously differentiable friction model has been developed to estimate the tire-road friction force. The differentiable friction model is more flexible and suitable for online adaptive identification and control with the advantage of more explicit parameterizable form. Different from conventional estimation methods, the filtered regression estimation parameter is introduced in the novel adaptive laws, which can guarantee that both the observer error and parameter error exponentially converge to zero. Lyapunov theory has been used to prove the stability of the proposed methods. The effectiveness of the estimation algorithm is illustrated via a bus simulation model in the Trucksim software and simulation environment. The relatively accurate tire-road friction force was estimated just by the easily existing sensors signals wheel rotational speed and vehicle speed and the proposed method also displays strong robustness against bounded disturbances.

  6. Exchange scattering as the driving force for ultrafast all-optical and bias-controlled reversal in ferrimagnetic metallic structures

    Science.gov (United States)

    Kalashnikova, A. M.; Kozub, V. I.

    2016-02-01

    Experimentally observed ultrafast all-optical magnetization reversal in ferrimagnetic metals and heterostructures based on antiferromagnetically coupled ferromagnetic d - and f -metallic layers relies on intricate energy and angular momentum flow between electrons, phonons, and spins. Here we treat the problem of angular momentum transfer in the course of ultrafast laser-induced dynamics in a ferrimagnetic metallic system using microscopical approach based on the system of rate equations. We show that the magnetization reversal is supported by a coupling of d and f subsystems to delocalized s or p electrons. The latter can transfer spin between the two subsystems in an incoherent way owing to the (s ;p )-(d ;f ) exchange scattering. Since the effect of the external excitation in this process is reduced to the transient heating of the mobile electron subsystem, we also discuss the possibility to trigger the magnetization reversal by applying a voltage bias pulse to antiferromagnetically coupled metallic ferromagnetic layers embedded in point contact or tunneling structures. We argue that such devices allow controlling reversal with high accuracy. We also suggest using the anomalous Hall effect to register the reversal, thus playing a role of reading probes.

  7. Adaptive social learning strategies in temporally and spatially varying environments : how temporal vs. spatial variation, number of cultural traits, and costs of learning influence the evolution of conformist-biased transmission, payoff-biased transmission, and individual learning.

    Science.gov (United States)

    Nakahashi, Wataru; Wakano, Joe Yuichiro; Henrich, Joseph

    2012-12-01

    Long before the origins of agriculture human ancestors had expanded across the globe into an immense variety of environments, from Australian deserts to Siberian tundra. Survival in these environments did not principally depend on genetic adaptations, but instead on evolved learning strategies that permitted the assembly of locally adaptive behavioral repertoires. To develop hypotheses about these learning strategies, we have modeled the evolution of learning strategies to assess what conditions and constraints favor which kinds of strategies. To build on prior work, we focus on clarifying how spatial variability, temporal variability, and the number of cultural traits influence the evolution of four types of strategies: (1) individual learning, (2) unbiased social learning, (3) payoff-biased social learning, and (4) conformist transmission. Using a combination of analytic and simulation methods, we show that spatial-but not temporal-variation strongly favors the emergence of conformist transmission. This effect intensifies when migration rates are relatively high and individual learning is costly. We also show that increasing the number of cultural traits above two favors the evolution of conformist transmission, which suggests that the assumption of only two traits in many models has been conservative. We close by discussing how (1) spatial variability represents only one way of introducing the low-level, nonadaptive phenotypic trait variation that so favors conformist transmission, the other obvious way being learning errors, and (2) our findings apply to the evolution of conformist transmission in social interactions. Throughout we emphasize how our models generate empirical predictions suitable for laboratory testing.

  8. Effects of carpal tunnel syndrome on adaptation of multi-digit forces to object weight for whole-hand manipulation.

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    Full Text Available The delicate tuning of digit forces to object properties can be disrupted by a number of neurological and musculoskeletal diseases. One such condition is Carpal Tunnel Syndrome (CTS, a compression neuropathy of the median nerve that causes sensory and motor deficits in a subset of digits in the hand. Whereas the effects of CTS on median nerve physiology are well understood, the extent to which it affects whole-hand manipulation remains to be addressed. CTS affects only the lateral three and a half digits, which raises the question of how the central nervous system integrates sensory feedback from affected and unaffected digits to plan and execute whole-hand object manipulation. We addressed this question by asking CTS patients and healthy controls to grasp, lift, and hold a grip device (445, 545, or 745 g for several consecutive trials. We found that CTS patients were able to successfully adapt grip force to object weight. However, multi-digit force coordination in patients was characterized by lower discrimination of force modulation to lighter object weights, higher across-trial digit force variability, the consistent use of excessively large digit forces across consecutive trials, and a lower ability to minimize net moments on the object. Importantly, the mechanical requirement of attaining equilibrium of forces and torques caused CTS patients to exert excessive forces at both CTS-affected digits and digits with intact sensorimotor capabilities. These findings suggest that CTS-induced deficits in tactile sensitivity interfere with the formation of accurate sensorimotor memories of previous manipulations. Consequently, CTS patients use compensatory strategies to maximize grasp stability at the expense of exerting consistently larger multi-digit forces than controls. These behavioral deficits might be particularly detrimental for tasks that require fine regulation of fingertip forces for manipulating light or fragile objects.

  9. Adaptation of muscle size and myofascial force transmission: a review and some new experimental results

    NARCIS (Netherlands)

    Huijing, P.A.; Jaspers, R.T.

    2005-01-01

    This paper considers the literature and some new experimental results important for adaptation of muscle fiber cross-sectional area and serial sarcomere number. Two major points emerge: (1) general rules for the regulation of adaptation (for in vivo immobilization, low gravity conditions, synergist

  10. Market Forces and Strategic Adaptation: The Influence of Private Scholarships on Planning in Urban School Systems.

    Science.gov (United States)

    St. John, Edward P.; Ridenour, Carolyn S.

    2001-01-01

    Examined the influence of a privately funded scholarship program on strategic adaptations within urban public and private schools. School administrators rapidly adapted their strategies to contend with the program. Suburban public schools prevented scholarship students from enrolling, urban public schools increased public school students' choices,…

  11. Adaptive local basis set for Kohn-Sham density functional theory in a discontinuous Galerkin framework II: Force, vibration, and molecular dynamics calculations

    CERN Document Server

    Zhang, Gaigong; Hu, Wei; Yang, Chao; Pask, John E

    2015-01-01

    Recently, we have proposed the adaptive local basis set for electronic structure calculations based on Kohn-Sham density functional theory in a pseudopotential framework. The adaptive local basis set is efficient and systematically improvable for total energy calculations. In this paper, we present the calculation of atomic forces, which can be used for a range of applications such as geometry optimization and molecular dynamics simulation. We demonstrate that, under mild assumptions, the computation of atomic forces can scale nearly linearly with the number of atoms in the system using the adaptive local basis set. We quantify the accuracy of the Hellmann-Feynman forces for a range of physical systems, benchmarked against converged planewave calculations, and find that the adaptive local basis set is efficient for both force and energy calculations, requiring at most a few tens of basis functions per atom to attain accuracy required in practice. Since the adaptive local basis set has implicit dependence on a...

  12. Neuronal adaptation effects in decision making

    OpenAIRE

    Theodoni, Panagiota; Kovacs, Gyula; Mark W Greenlee; Deco, Gustavo

    2011-01-01

    Recently, there has been an increased interest on the neural mechanisms underlying perceptual decision making. However, the effect of neuronal adaptation in this context has not yet been studied. We begin our study by investigating how adaptation can bias perceptual decisions. We considered behavioral data from an experiment on high-level adaptation-related aftereffects in a perceptual decision task with ambiguous stimuli on humans. To understand the driving force behind the perceptual decisi...

  13. Rapid changes in corticospinal excitability during force field adaptation of human walking

    DEFF Research Database (Denmark)

    Barthélemy, Dorothy; Alain, S; Grey, Michael James;

    2012-01-01

    be explained by changes in background TA EMG activity. These effects seemed specific to walking, as similar changes in TA MEP were not seen when seated subjects were tested during static dorsiflexion. These observations suggest that the corticospinal tract contributes to the adaptation of walking...

  14. Adaptive Neuro-Fuzzy Inference System Models for Force Prediction of a Mechatronic Flexible Structure

    DEFF Research Database (Denmark)

    Achiche, S.; Shlechtingen, M.; Raison, M.;

    2016-01-01

    of the sampling frequency and sensor location on the model performance is investigated. The results obtained in this paper show that ANFIS models can be used to set up reliable force predictors for dynamical loaded flexible structures, when a certain degree of inaccuracy is accepted. Furthermore, the comparison...... the models using only current values have generally higher prediction errors in trained regions but are less sensitive to changes of the system dynamics history....

  15. Adapting MRI Acoustic Radiation Force Imaging For In Vivo Human Brain Focused Ultrasound Applications

    OpenAIRE

    Kaye, Elena A.; Pauly, Kim Butts

    2012-01-01

    A variety of MRI acoustic radiation force imaging (MR-ARFI) pulse sequences as the means for image guidance of focused ultrasound therapy have been recently developed and tested ex vivo and in animal models. To successfully translate MR-ARFI guidance into human applications, ensuring that MR-ARFI provides satisfactory image quality in the presence of patient motion and deposits safe amount of ultrasound energy during image acquisition is necessary. The first aim of this work was to study the ...

  16. Using an electrohydraulic ankle foot orthosis to study modifications in feedforward control during locomotor adaptation to force fields applied in stance

    Directory of Open Access Journals (Sweden)

    Bouyer Laurent J

    2009-06-01

    Full Text Available Abstract Background Adapting to external forces during walking has been proposed as a tool to improve locomotion after central nervous system injury. However, sensorimotor integration during walking varies according to the timing in the gait cycle, suggesting that adaptation may also depend on gait phases. In this study, an ElectroHydraulic AFO (EHO was used to apply forces specifically during mid-stance and push-off to evaluate if feedforward movement control can be adapted in these 2 gait phases. Methods Eleven healthy subjects walked on a treadmill before (3 min, during (5 min and after (5 min exposure to 2 force fields applied by the EHO (mid-stance/push-off; ~10 Nm, towards dorsiflexion. To evaluate modifications in feedforward control, strides with no force field ('catch strides' were unexpectedly inserted during the force field walking period. Results When initially exposed to a mid-stance force field (FF20%, subjects showed a significant increase in ankle dorsiflexion velocity. Catches applied early into the FF20% were similar to baseline (P > 0.99. Subjects gradually adapted by returning ankle velocity to baseline over ~50 strides. Catches applied thereafter showed decreased ankle velocity where the force field was normally applied, indicating the presence of feedforward adaptation. When initially exposed to a push-off force field (FF50%, plantarflexion velocity was reduced in the zone of force field application. No adaptation occurred over the 5 min exposure. Catch strides kinematics remained similar to control at all times, suggesting no feedforward adaptation. As a control, force fields assisting plantarflexion (-3.5 to -9.5 Nm were applied and increased ankle plantarflexion during push-off, confirming that the lack of kinematic changes during FF50% catch strides were not simply due to a large ankle impedance. Conclusion Together these results show that ankle exoskeletons such as the EHO can be used to study phase-specific adaptive

  17. A New Optimized Data Clustering Technique using Cellular Automata and Adaptive Central Force Optimization (ACFO

    Directory of Open Access Journals (Sweden)

    G. Srinivasa Rao

    2015-06-01

    Full Text Available As clustering techniques are gaining more important today, we propose a new clustering technique by means of ACFO and cellular automata. The cellular automata uniquely characterizes the condition of a cell at a specific moment by employing the data like the conditions of a reference cell together with its adjoining cell, total number of cells, restraint, transition function and neighbourhood calculation. With an eye on explaining the condition of the cell, morphological functions are executed on the image. In accordance with the four stages of the morphological process, the rural and the urban areas are grouped separately. In order to steer clear of the stochastic turbulences, the threshold is optimized by means of the ACFO. The test outcomes obtained vouchsafe superb performance of the innovative technique. The accomplishment of the new-fangled technique is assessed by using additional number of images and is contrasted with the traditional methods like CFO (Central Force Optimization and PSO (Particle Swarm Optimization.

  18. Effect of blocking tactile information from the fingertips on adaptation and execution of grip forces to friction at the grasping surface.

    Science.gov (United States)

    Bilaloglu, Seda; Lu, Ying; Geller, Daniel; Rizzo, John Ross; Aluru, Viswanath; Gardner, Esther P; Raghavan, Preeti

    2016-03-01

    Adaptation of fingertip forces to friction at the grasping surface is necessary to prevent use of inadequate or excessive grip forces. In the current study we investigated the effect of blocking tactile information from the fingertips noninvasively on the adaptation and efficiency of grip forces to surface friction during precision grasp. Ten neurologically intact subjects grasped and lifted an instrumented grip device with 18 different frictional surfaces under three conditions: with bare hands or with a thin layer of plastic (Tegaderm) or an additional layer of foam affixed to the fingertips. The coefficient of friction at the finger-object interface of each surface was obtained for each subject with bare hands and Tegaderm by measuring the slip ratio (grip force/load force) at the moment of slip. We found that the foam layer reduced sensibility for two-point discrimination and pressure sensitivity at the fingertips, but Tegaderm did not. However, Tegaderm reduced static, but not dynamic, tactile discrimination. Adaptation of fingertip grip forces to surface friction measured by the rate of change of peak grip force, and grip force efficiency measured by the grip-load force ratio at lift, showed a proportional relationship with bare hands but were impaired with Tegaderm and foam. Activation of muscles engaged in precision grip also varied with the frictional surface with bare hands but not with Tegaderm and foam. The results suggest that sensitivity for static tactile discrimination is necessary for feedforward and feedback control of grip forces and for adaptive modulation of muscle activity during precision grasp. PMID:26655820

  19. Adapt

    Science.gov (United States)

    Bargatze, L. F.

    2015-12-01

    Active Data Archive Product Tracking (ADAPT) is a collection of software routines that permits one to generate XML metadata files to describe and register data products in support of the NASA Heliophysics Virtual Observatory VxO effort. ADAPT is also a philosophy. The ADAPT concept is to use any and all available metadata associated with scientific data to produce XML metadata descriptions in a consistent, uniform, and organized fashion to provide blanket access to the full complement of data stored on a targeted data server. In this poster, we present an application of ADAPT to describe all of the data products that are stored by using the Common Data File (CDF) format served out by the CDAWEB and SPDF data servers hosted at the NASA Goddard Space Flight Center. These data servers are the primary repositories for NASA Heliophysics data. For this purpose, the ADAPT routines have been used to generate data resource descriptions by using an XML schema named Space Physics Archive, Search, and Extract (SPASE). SPASE is the designated standard for documenting Heliophysics data products, as adopted by the Heliophysics Data and Model Consortium. The set of SPASE XML resource descriptions produced by ADAPT includes high-level descriptions of numerical data products, display data products, or catalogs and also includes low-level "Granule" descriptions. A SPASE Granule is effectively a universal access metadata resource; a Granule associates an individual data file (e.g. a CDF file) with a "parent" high-level data resource description, assigns a resource identifier to the file, and lists the corresponding assess URL(s). The CDAWEB and SPDF file systems were queried to provide the input required by the ADAPT software to create an initial set of SPASE metadata resource descriptions. Then, the CDAWEB and SPDF data repositories were queried subsequently on a nightly basis and the CDF file lists were checked for any changes such as the occurrence of new, modified, or deleted

  20. Using NEON to Measure Adaptation of Vegetation to Changes in Environmental Forcing

    Science.gov (United States)

    Martin, P. H.; Kao, R.; Gibson, C.

    2009-12-01

    The National Ecological Observatory Network (NEON) is a national-scale research platform for documenting and analyzing the impacts of climate change, land-use change, and invasive species on ecology. NEON features sensor networks and experiments linked by cyberinfrastructure to record and archive ecological data for at least 30 years. NEON partitions the United States into 20 ecoclimatic domains. Each domain hosts one fully instrumented core site in a wildland area and two re-locatable sites, which aims to capture ecologically significant gradients (e.g. landuse). Using standardized protocols and an open data policy, NEON data will be gathered from the level of the gene and organism to populations and communities, with extrapolations to the continental scale. In conjunction with environmental data, NEON will conduct field observations and analyses of biological specimens to track biodiversity, population dynamics, productivity, phenology, infectious disease, biogeochemistry and ecohydrology. Here we present a few examples of the type of research NEON will enable using this data. The NEON network will measure and scale many environmental factors that affect vegetation, e.g. temperature, precipitation, and nutrient availability. Direct monitoring of vegetation will enable the study of acclimatory and adaptive changes in vegetation properties over different time scales. Such data will improve the representation of vegetation responses to environmental change in models. The vision behind NEON aims to advance our ability to quantitatively predict ecological change.

  1. Implementation of a Zero-Forcing Precoding Algorithm Combined with Adaptive Beamforming Based on WiMAX System

    Directory of Open Access Journals (Sweden)

    Hyunwook Yang

    2013-01-01

    Full Text Available We propose a novel precoding algorithm that is a zero-forcing (ZF method combined with adaptive beamforming in the Worldwide Interoperability for Microwave Access (WiMAX system. In a Multiuser Multiple-Input Multiple-Output (MU-MIMO system, ZF is used to eliminate the Multiple Access Interference (MAI in order to allow several users to share a common resource. The adaptive beamforming algorithm is used to achieve the desired SNR gain. The experimental system consists of a WiMAX base station that has 2 MIMO elements, each of which is composed of three-array antennas and two mobile terminals, each of which has a single antenna. Through computer simulations, we verified that the proposed method outperforms the conventional ZF method by at least 2.4 dB when the BER is 0.1%, or 1.7 dB when the FER is 1%, in terms of the SNR. Through a hardware implementation of the proposed method, we verified the feasibility of the proposed method for realizing a practical WiMAX base station to utilize the channel resources as efficiently as possible.

  2. WE-G-BRF-09: Force- and Image-Adaptive Strategies for Robotised Placement of 4D Ultrasound Probes

    International Nuclear Information System (INIS)

    Purpose: To allow continuous acquisition of high quality 4D ultrasound images for non-invasive live tracking of tumours for IGRT, image- and force-adaptive strategies for robotised placement of 4D ultrasound probes are developed and evaluated. Methods: The developed robotised ultrasound system is based on a 6-axes industrial robot (adept Viper s850) carrying a 4D ultrasound transducer with a mounted force-torque sensor. The force-adaptive placement strategies include probe position control using artificial potential fields and contact pressure regulation by a PD controller strategy. The basis for live target tracking is a continuous minimum contact pressure to ensure good image quality and high patient comfort. This contact pressure can be significantly disturbed by respiratory movements and has to be compensated. All measurements were performed on human subjects under realistic conditions. When performing cardiac ultrasound, rib- and lung shadows are a common source of interference and can disrupt the tracking. To ensure continuous tracking, these artefacts had to be detected to automatically realign the probe. The detection is realised by multiple algorithms based on entropy calculations as well as a determination of the image quality. Results: Through active contact pressure regulation it was possible to reduce the variance of the contact pressure by 89.79% despite respiratory motion of the chest. The results regarding the image processing clearly demonstrate the feasibility to detect image artefacts like rib shadows in real-time. Conclusion: In all cases, it was possible to stabilise the image quality by active contact pressure control and automatically detected image artefacts. This fact enables the possibility to compensate for such interferences by realigning the probe and thus continuously optimising the ultrasound images. This is a huge step towards fully automated transducer positioning and opens the possibility for stable target tracking in

  3. WE-G-BRF-09: Force- and Image-Adaptive Strategies for Robotised Placement of 4D Ultrasound Probes

    Energy Technology Data Exchange (ETDEWEB)

    Kuhlemann, I [Institute for Robotics and Cognitive Systems, University of Luebeck, Luebeck (Germany); Graduate School for Computing in Life Science, University of Luebeck, Luebeck (Germany); Bruder, R; Ernst, F; Schweikard, A [Institute for Robotics and Cognitive Systems, University of Luebeck, Luebeck (Germany)

    2014-06-15

    Purpose: To allow continuous acquisition of high quality 4D ultrasound images for non-invasive live tracking of tumours for IGRT, image- and force-adaptive strategies for robotised placement of 4D ultrasound probes are developed and evaluated. Methods: The developed robotised ultrasound system is based on a 6-axes industrial robot (adept Viper s850) carrying a 4D ultrasound transducer with a mounted force-torque sensor. The force-adaptive placement strategies include probe position control using artificial potential fields and contact pressure regulation by a PD controller strategy. The basis for live target tracking is a continuous minimum contact pressure to ensure good image quality and high patient comfort. This contact pressure can be significantly disturbed by respiratory movements and has to be compensated. All measurements were performed on human subjects under realistic conditions. When performing cardiac ultrasound, rib- and lung shadows are a common source of interference and can disrupt the tracking. To ensure continuous tracking, these artefacts had to be detected to automatically realign the probe. The detection is realised by multiple algorithms based on entropy calculations as well as a determination of the image quality. Results: Through active contact pressure regulation it was possible to reduce the variance of the contact pressure by 89.79% despite respiratory motion of the chest. The results regarding the image processing clearly demonstrate the feasibility to detect image artefacts like rib shadows in real-time. Conclusion: In all cases, it was possible to stabilise the image quality by active contact pressure control and automatically detected image artefacts. This fact enables the possibility to compensate for such interferences by realigning the probe and thus continuously optimising the ultrasound images. This is a huge step towards fully automated transducer positioning and opens the possibility for stable target tracking in

  4. Adaptive-optic approach to mitigating aero-optic disturbances for a forced shear layer

    Science.gov (United States)

    Nightingale, Alice M.

    Non-uniform, variable-density fields, resulting from compressibility effects in turbulent flows, are the source of aero-optical distortions which cause significant reductions in optical system performance. As a laser beam transverses through an optically active medium, containing index-of-refraction variations, several optical phenomena occur including beam wander, image distortion, and beam defocus. When encountering a variation in the index field, light waves refract causing an otherwise planar wavefront of a laser beam to become aberrated, contributing to the adverse effects mentioned above. Adaptive-Optics (AO) is a technique used to correct for such spatially and temporally varying aberrations on an optical beam by applying a conjugate waveform correction prior to the beams transmission through the flow. Conventional AO systems are bandwidth limited by real-time processing issues and wavefront sensor limitations. Therefore, an alternative to the conventional AO approach has been proposed, developed and evaluated with the goal of overcoming such bandwidth limitations. The alternative AO system, presented throughout this document, consists of two main features; feed-forward flow control and a phase-locked-loop AO control strategy. Initially irregular, unpredictable large-scale structures within a shear layer are regularized using flow control. Subsequently, the resulting optical wavefront, and corresponding optical signal, emerging from the regularized flow becomes more periodic and predictable effectively reducing the bandwidth necessary to make real-time corrections. A phase-lock-loop controller is then used to perform real-time corrections. Wavefront corrections are estimated based upon the regularized flow, while two small aperture laser beams provide a non-intrusive means of acquiring amplitude and phase error measurements. The phase-lock-loop controller uses these signals as feedback to synchronize the deformable mirror's waveform to that of the shear

  5. Automobile or other conveyance and adaptive equipment certificate of eligibility for veterans or members of the armed forces with amyotrophic lateral sclerosis. Interim final rule.

    Science.gov (United States)

    2015-02-25

    The Department of Veterans Affairs (VA) is amending its adjudication regulation regarding certificates of eligibility for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment. The amendment authorizes automatic issuance of a certificate of eligibility for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment to all veterans with service-connected amyotrophic lateral sclerosis (ALS) and members of the Armed Forces serving on active duty with ALS.

  6. An overview of the activities of the OECD/NEA Task Force on adapting computer codes in nuclear applications to parallel architectures

    International Nuclear Information System (INIS)

    Subsequent to the introduction of High Performance Computing in the developed countries, the Organization for Economic Cooperation and Development/Nuclear Energy Agency (OECD/NEA) created the Task Force on Adapting Computer Codes in Nuclear Applications to Parallel Architectures (under the guidance of the Nuclear Science Committee's Working Party on Advanced Computing) to study the growth area in supercomputing and its applicability to the nuclear community's computer codes. The result has been four years of investigation for the Task Force in different subject fields - deterministic and Monte Carlo radiation transport, computational mechanics and fluid dynamics, nuclear safety, atmospheric models and waste management

  7. Adaptation of the pituitary-adrenal axis to daily repeated forced swim exposure in rats is dependent on the temperature of water.

    Science.gov (United States)

    Rabasa, Cristina; Delgado-Morales, Raúl; Gómez-Román, Almudena; Nadal, Roser; Armario, Antonio

    2013-11-01

    Comparison of exposure to certain predominantly emotional stressors reveals a qualitatively similar neuroendocrine response profile as well as a reduction of physiological responses after daily repeated exposure (adaptation). However, particular physical components of the stressor may interfere with adaptation. As defective adaptation to stress can enhance the probability to develop pathologies, we studied in adult male rats (n = 10/group) swimming behavior (struggling, immobility and mild swim) and physiological responses (ACTH, corticosterone and rectal temperature) to daily repeated exposure to forced swim (20 min, 13 d) at 25 or 36 °C (swim25 or swim36). Rats were repeatedly blood-sampled by tail-nick and hormones measured by radioimmunoassay. Some differences were observed between the two swim temperature groups after the first exposure to forced swim: (a) active behaviors were greater in swim25 than swim36 groups; (b) swim25 but not swim36 caused hypothermia; and (c) swim36 elicited the same ACTH response as swim25, but plasma corticosterone concentration was lower for swim36 at 30 min post-swim. After daily repeated exposure, adaptation in ACTH secretion was observed with swim36 already on day 4, whereas with swim25 adaptation was not observed until day 13 and was of lower magnitude. Nevertheless, after repeated exposure to swim25 a partial protection from hypothermia was observed and the two swim conditions resulted in progressive reduction of active behaviors. Thus, daily repeated swim at 25 °C impairs adaptation of the hypothalamic-pituitary-adrenal axis as compared to swim at 36 °C, supporting the hypothesis that certain physical components of predominantly emotional stressors can interfere with the process of adaptation.

  8. Adapted Physical Activity Programme and Self-Perception in Obese Adolescents with Intellectual Disability: Between Morphological Awareness and Positive Illusory Bias

    Science.gov (United States)

    Salaun, Laureline; Reynes, Eric; Berthouze-Aranda, Sophie E.

    2014-01-01

    Background: In adolescents with intellectual disability, the management of obesity is a crucial issue, yet also quite complex because of their particular perception of themselves. This study investigated the relationship between self-perception variables and morphological variables and their changes after a 9-month Adapted Physical Activity (APA)…

  9. Regional vertical total electron content (VTEC) modeling together with satellite and receiver differential code biases (DCBs) using semi-parametric multivariate adaptive regression B-splines (SP-BMARS)

    Science.gov (United States)

    Durmaz, Murat; Karslioglu, Mahmut Onur

    2015-04-01

    There are various global and regional methods that have been proposed for the modeling of ionospheric vertical total electron content (VTEC). Global distribution of VTEC is usually modeled by spherical harmonic expansions, while tensor products of compactly supported univariate B-splines can be used for regional modeling. In these empirical parametric models, the coefficients of the basis functions as well as differential code biases (DCBs) of satellites and receivers can be treated as unknown parameters which can be estimated from geometry-free linear combinations of global positioning system observables. In this work we propose a new semi-parametric multivariate adaptive regression B-splines (SP-BMARS) method for the regional modeling of VTEC together with satellite and receiver DCBs, where the parametric part of the model is related to the DCBs as fixed parameters and the non-parametric part adaptively models the spatio-temporal distribution of VTEC. The latter is based on multivariate adaptive regression B-splines which is a non-parametric modeling technique making use of compactly supported B-spline basis functions that are generated from the observations automatically. This algorithm takes advantage of an adaptive scale-by-scale model building strategy that searches for best-fitting B-splines to the data at each scale. The VTEC maps generated from the proposed method are compared numerically and visually with the global ionosphere maps (GIMs) which are provided by the Center for Orbit Determination in Europe (CODE). The VTEC values from SP-BMARS and CODE GIMs are also compared with VTEC values obtained through calibration using local ionospheric model. The estimated satellite and receiver DCBs from the SP-BMARS model are compared with the CODE distributed DCBs. The results show that the SP-BMARS algorithm can be used to estimate satellite and receiver DCBs while adaptively and flexibly modeling the daily regional VTEC.

  10. Human-machine interaction force control:using a model-referenced adaptive impedance device to control an index finger exoskeleton

    Institute of Scientific and Technical Information of China (English)

    Qian BI; Can-jun YANG

    2014-01-01

    Exoskeleton robots and their control methods have been extensively developed to aid post-stroke rehabilitation. Most of the existing methods using linear controllers are designed for position control and are not suitable for human-machine interaction (HMI) force control, as the interaction system between the human body and exoskeleton is uncertain and nonlinear. We present an approach for HMI force control via model reference adaptive impedance control (MRAIC) to solve this problem in case of index finger exoskeleton control. First, a dynamic HMI model, which is based on a position control inner loop, is for-mulated. Second, the theoretical MRAC framework is implemented in the control system. Then, the adaptive controllers are designed according to the Lyapunov stability theory. To verify the performance of the proposed method, we compare it with a proportional-integral-derivative (PID) method in the time domain with real experiments and in the frequency domain with simu-lations. The results illustrate the effectiveness and robustness of the proposed method in solving the nonlinear HMI force control problem in hand exoskeleton.

  11. Driving-force compensation to improve the bias thermal stability of MEMS gyroscopes%改善MEMS陀螺误差温度稳定性的驱动力补偿方法

    Institute of Scientific and Technical Information of China (English)

    刘宇航; 陈志勇; 张嵘

    2013-01-01

    由于微机电系统(MEMS)陀螺通常采用微加工工艺生产制造,因此总是受微加工过程带来的的各种精度缺陷影响.对于MEMS陀螺,其零位输出误差因受环境因素影响而无法保持稳定,随时间表现出漂移特性,这种特性严重限制了MEMS陀螺在更高精度应用中的可用性.该文研究了一种改善MEMS陀螺零位误差温度稳定性的方法.通过分析陀螺运动特性及主要误差源,阐明陀螺驱动力对检测方向的耦合作用是零偏误差同相分量产生并随温度漂移的主要原因之一.为抑制陀螺驱动力耦合作用,提出对陀螺检测轴施加补偿静电力的方法.温度试验结果表明:施加补偿作用后,陀螺零偏误差同相分量的温度稳定性在12~60℃范围内提高了3倍以上.%Micro electro mechanical system (MEMS) gyroscopes can be manufactured using micro-machining procedures,but they are all subject to unavoidable defects related to the fabrication processes.The zero-rate output (ZRO) of a MEMS gyroscope is known to vary with the environment which severely restricts high-precision applications.This paper presents a method to improve MEMS gyroscope thermal stability during temperature variations.Analysis of the gyro's error sources and fundamental dynamics show that the coupling of driving forces has a crucial effect on the in phase ZRO and also contributes to the instabilities of the gyro's bias.The coupling of the gyro driving forces can be suppressed by electrostatic force compensation applied to the sensing axis with temperature tests showing that the gyro bias is three times more stable after compensation for temperatures of 12 ~ 60℃.

  12. Automobile or Other Conveyance and Adaptive Equipment Certificate of Eligibility for Veterans or Members of the Armed Forces With Amyotrophic Lateral Sclerosis Connected to Military Service. Final rule.

    Science.gov (United States)

    2016-01-13

    The Department of Veterans Affairs (VA) published an Interim Final Rule on February 25, 2015, to amend its adjudication regulations to provide a certificate of eligibility for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment for all veterans with service-connected amyotrophic lateral sclerosis (ALS) and servicemembers serving on active duty with ALS. The amendment authorized automatic issuance of a certificate of eligibility for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment to all veterans with service-connected ALS and members of the Armed Forces serving on active duty with ALS. The intent of this final rule is to confirm the amendment made by the interim final rule without change.

  13. Biased Allostery.

    Science.gov (United States)

    Edelstein, Stuart J; Changeux, Jean-Pierre

    2016-09-01

    G-protein-coupled receptors (GPCRs) constitute a large group of integral membrane proteins that transduce extracellular signals from a wide range of agonists into targeted intracellular responses. Although the responses can vary depending on the category of G-proteins activated by a particular receptor, responses were also found to be triggered by interactions of the receptor with β-arrestins. It was subsequently discovered that for the same receptor molecule (e.g., the β-adrenergic receptor), some agonists have a propensity to specifically favor responses by G-proteins, others by β-arrestins, as has now been extensively studied. This feature of the GPCR system is known as biased agonism and is subject to various interpretations, including agonist-induced conformational change versus selective stabilization of preexisting active conformations. Here, we explore a complete allosteric framework for biased agonism based on alternative preexisting conformations that bind more strongly, but nonexclusively, either G-proteins or β-arrestins. The framework incorporates reciprocal effects among all interacting molecules. As a result, G-proteins and β-arrestins are in steric competition for binding to the cytoplasmic surface of either the G-protein-favoring or β-arrestin-favoring GPCR conformation. Moreover, through linkage relations, the strength of the interactions of G-proteins or β-arrestins with the corresponding active conformation potentiates the apparent affinity for the agonist, effectively equating these two proteins to allosteric modulators. The balance between response alternatives can also be influenced by the physiological concentrations of either G-proteins or β-arrestins, as well as by phosphorylation or interactions with positive or negative allosteric modulators. The nature of the interactions in the simulations presented suggests novel experimental tests to distinguish more fully among alternative mechanisms. PMID:27602718

  14. Cognitive biases and language universals

    CERN Document Server

    Baronchelli, Andrea; Puglisi, Andrea

    2013-01-01

    Language universals have been longly attributed to an innate Universal Grammar. An alternative explanation states that linguistic universals emerged independently in every language in response to shared cognitive, though non language-specific, biases. A computational model has recently shown how this could be the case, focusing on the paradigmatic example of the universal properties of color naming patterns, and producing results in accurate agreement with the experimental data. Here we investigate thoroughly the role of a cognitive bias in the framework of this model. We study how, and to what extent, the structure of the bias can influence the corresponding linguistic universal patterns. We show also that the cultural history of a group of speakers introduces population-specific constraints that act against the uniforming pressure of the cognitive bias, and we clarify the interplay between these two forces. We believe that our simulations can help to shed light on the possible mechanisms at work in the evol...

  15. Effects of Carpal Tunnel Syndrome on adaptation of multi-digit forces to object mass distribution for whole-hand manipulation

    Directory of Open Access Journals (Sweden)

    Zhang Wei

    2012-11-01

    Full Text Available Abstract Background Carpal tunnel syndrome (CTS is a compression neuropathy of the median nerve that results in sensorimotor deficits in the hand. Until recently, the effects of CTS on hand function have been studied using mostly two-digit grip tasks. The purpose of this study was to investigate the coordination of multi-digit forces as a function of object center of mass (CM during whole-hand grasping. Methods Fourteen CTS patients and age- and gender-matched controls were instructed to grasp, lift, hold, and release a grip device with five digits for seven consecutive lifts while maintaining its vertical orientation. The object CM was changed by adding a mass at different locations at the base of the object. We measured forces and torques exerted by each digit and object kinematics and analyzed modulation of these variables to object CM at object lift onset and during object hold. Our task requires a modulation of digit forces at and after object lift onset to generate a compensatory moment to counteract the external moment caused by the added mass and to minimize object tilt. Results We found that CTS patients learned to generate a compensatory moment and minimized object roll to the same extent as controls. However, controls fully exploited the available degrees of freedom (DoF in coordinating their multi-digit forces to generate a compensatory moment, i.e., digit normal forces, tangential forces, and the net center of pressure on the finger side of the device at object lift onset and during object hold. In contrast, patients modulated only one of these DoFs (the net center of pressure to object CM by modulating individual normal forces at object lift onset. During object hold, however, CTS patients were able to modulate digit tangential force distribution to object CM. Conclusions Our findings suggest that, although CTS did not affect patients’ ability to perform our manipulation task, it interfered with the modulation of specific grasp

  16. Adaptive Image-Guided Radiotherapy (IGRT) Eliminates the Risk of Biochemical Failure Caused by the Bias of Rectal Distension in Prostate Cancer Treatment Planning: Clinical Evidence

    International Nuclear Information System (INIS)

    Purpose: Rectal distension has been shown to decrease the probability of biochemical control. Adaptive image-guided radiotherapy (IGRT) corrects for target position and volume variations, reducing the risk of biochemical failure while yielding acceptable rates of gastrointestinal (GI)/genitourinary (GU) toxicities. Methods and Materials: Between 1998 and 2006, 962 patients were treated with computed tomography (CT)-based offline adaptive IGRT. Patients were stratified into low (n = 400) vs. intermediate/high (n = 562) National Comprehensive Cancer Network (NCCN) risk groups. Target motion was assessed with daily CT during the first week. Electronic portal imaging device (EPID) was used to measure daily setup error. Patient-specific confidence-limited planning target volumes (cl-PTV) were then constructed, reducing the standard PTV and compensating for geometric variation of the target and setup errors. Rectal volume (RV), cross-sectional area (CSA), and rectal volume from the seminal vesicles to the inferior prostate (SVP) were assessed on the planning CT. The impact of these volumetric parameters on 5-year biochemical control (BC) and chronic Grades ≥2 and 3 GU and GI toxicity were examined. Results: Median follow-up was 5.5 years. Median minimum dose covering cl-PTV was 75.6 Gy. Median values for RV, CSA, and SVP were 82.8 cm3, 5.6 cm2, and 53.3 cm3, respectively. The 5-year BC was 89% for the entire group: 96% for low risk and 83% for intermediate/high risk (p < 0.001). No statistically significant differences in BC were seen with stratification by RV, CSA, and SVP in quartiles. Maximum chronic Grades ≥2 and 3 GI toxicities were 21.2% and 2.9%, respectively. Respective values for GU toxicities were 15.5% and 4.3%. No differences in GI or GU toxicities were noted when patients were stratified by RV. Conclusions: Incorporation of adaptive IGRT reduces the risk of geometric miss and results in excellent biochemical control that is independent of rectal volume

  17. Adaptive Image-Guided Radiotherapy (IGRT) Eliminates the Risk of Biochemical Failure Caused by the Bias of Rectal Distension in Prostate Cancer Treatment Planning: Clinical Evidence

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sean S.; Yan Di; McGrath, Samuel; Dilworth, Joshua T.; Liang Jian; Ye Hong; Krauss, Daniel J.; Martinez, Alvaro A. [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan (United States); Kestin, Larry L., E-mail: lkestin@comcast.net [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan (United States)

    2012-07-01

    Purpose: Rectal distension has been shown to decrease the probability of biochemical control. Adaptive image-guided radiotherapy (IGRT) corrects for target position and volume variations, reducing the risk of biochemical failure while yielding acceptable rates of gastrointestinal (GI)/genitourinary (GU) toxicities. Methods and Materials: Between 1998 and 2006, 962 patients were treated with computed tomography (CT)-based offline adaptive IGRT. Patients were stratified into low (n = 400) vs. intermediate/high (n = 562) National Comprehensive Cancer Network (NCCN) risk groups. Target motion was assessed with daily CT during the first week. Electronic portal imaging device (EPID) was used to measure daily setup error. Patient-specific confidence-limited planning target volumes (cl-PTV) were then constructed, reducing the standard PTV and compensating for geometric variation of the target and setup errors. Rectal volume (RV), cross-sectional area (CSA), and rectal volume from the seminal vesicles to the inferior prostate (SVP) were assessed on the planning CT. The impact of these volumetric parameters on 5-year biochemical control (BC) and chronic Grades {>=}2 and 3 GU and GI toxicity were examined. Results: Median follow-up was 5.5 years. Median minimum dose covering cl-PTV was 75.6 Gy. Median values for RV, CSA, and SVP were 82.8 cm{sup 3}, 5.6 cm{sup 2}, and 53.3 cm{sup 3}, respectively. The 5-year BC was 89% for the entire group: 96% for low risk and 83% for intermediate/high risk (p < 0.001). No statistically significant differences in BC were seen with stratification by RV, CSA, and SVP in quartiles. Maximum chronic Grades {>=}2 and 3 GI toxicities were 21.2% and 2.9%, respectively. Respective values for GU toxicities were 15.5% and 4.3%. No differences in GI or GU toxicities were noted when patients were stratified by RV. Conclusions: Incorporation of adaptive IGRT reduces the risk of geometric miss and results in excellent biochemical control that is

  18. A Self-Adaptive Steered Molecular Dynamics Method Based on Minimization of Stretching Force Reveals the Binding Affinity of Protein–Ligand Complexes

    Directory of Open Access Journals (Sweden)

    Junfeng Gu

    2015-10-01

    Full Text Available Binding affinity prediction of protein–ligand complexes has attracted widespread interest. In this study, a self-adaptive steered molecular dynamics (SMD method is proposed to reveal the binding affinity of protein–ligand complexes. The SMD method is executed through adjusting pulling direction to find an optimum trajectory of ligand dissociation, which is realized by minimizing the stretching force automatically. The SMD method is then used to simulate the dissociations of 19 common protein–ligand complexes which are derived from two homology families, and the binding free energy values are gained through experimental techniques. Results show that the proposed SMD method follows a different dissociation pathway with lower a rupture force and energy barrier when compared with the conventional SMD method, and further analysis indicates the rupture forces of the complexes in the same protein family correlate well with their binding free energy, which reveals the possibility of using the proposed SMD method to identify the active ligand.

  19. Response and adaptation of grapevine cultivars to hydrological conditions forced by a changing climate in a complex landscape

    Science.gov (United States)

    De Lorenzi, Francesca; Bonfante, Antonello; Alfieri, Silvia Maria; Monaco, Eugenia; De Mascellis, Roberto; Manna, Piero; Menenti, Massimo

    2014-05-01

    requirements were determined. To assess cultivars adaptability, hydrological requirements were evaluated against hydrological indicators. A probabilistic assessment of adaptability was performed, and the inaccuracy of estimated hydrological requirements was accounted for by the error of estimate and its distribution. Maps of cultivars potential distribution, i.e. locations where each cultivar is expected to be compatible with climate, were derived and possible options for adaptation to climate change were defined. The 2021 - 2050 climate scenario was characterized by higher temperatures throughout the year and by a significant decrease in precipitation during spring and autumn. The results have shown the relevant variability of soils water regime and its effects on cultivars adaptability. In the future climate scenario, a hydrological indicator (i.e. relative evapotranspiration deficit - RETD), averaged over the growing season, showed an average increase of 5-8 %, and more pronounced increases occurred in the phenological phases of berry formation and ripening. At the locations where soil hydrological conditions were favourable (like the ancient terraces), hydrological indicators were quite similar in both climate scenarios and the adaptability of the cultivars was high both in the reference and future climate case. The work was carried out within the Italian national project AGROSCENARI funded by the Ministry for Agricultural, Food and Forest Policies (MIPAAF, D.M. 8608/7303/2008) Keywords: climate change, Vitis vinifera L., simulation model, yield response functions, potential cultivation area.

  20. Investigating Endogeneity Bias in Marketing

    OpenAIRE

    Qing Liu; Thomas Otter; Greg M. Allenby

    2007-01-01

    The use of adaptive designs in conjoint analysis has been shown to lead to an endogeneity bias in part-worth estimates using sampling experiments. In this paper, we re-examine the endogeneity issue in light of the likelihood principle. The likelihood principle asserts that all relevant information in the data about model parameters is contained in the likelihood function. We show that, once the data are collected, adhering to the likelihood principle leads to analysis where endogeneity become...

  1. Awareness Reduces Racial Bias

    OpenAIRE

    Pope, Devin G.; Price, Joseph; Wolfers, Justin

    2014-01-01

    Can raising awareness of racial bias subsequently reduce that bias? We address this question by exploiting the widespread media attention highlighting racial bias among professional basketball referees that occurred in May 2007 following the release of an academic study. Using new data, we confirm that racial bias persisted in the years after the study's original sample, but prior to the media coverage. Subsequent to the media coverage though, the bias completely disappeared. We examine poten...

  2. Application and investigation of a bound for outcome reporting bias

    OpenAIRE

    Gamble Carrol; Williamson Paula R

    2007-01-01

    Abstract Background Direct empirical evidence for the existence of outcome reporting bias is accumulating and this source of bias is recognised as a potential threat to the validity of meta-analysis of randomised clinical trials. Methods A method for calculating the maximum bias in a meta-analysis due to publication bias is adapted for the setting where within-study selective non-reporting of outcomes is suspected, and compared to the alternative approach of missing data imputation. The prope...

  3. Hotspots of biased nucleotide substitutions in human genes.

    Directory of Open Access Journals (Sweden)

    Jonas Berglund

    2009-01-01

    Full Text Available Genes that have experienced accelerated evolutionary rates on the human lineage during recent evolution are candidates for involvement in human-specific adaptations. To determine the forces that cause increased evolutionary rates in certain genes, we analyzed alignments of 10,238 human genes to their orthologues in chimpanzee and macaque. Using a likelihood ratio test, we identified protein-coding sequences with an accelerated rate of base substitutions along the human lineage. Exons evolving at a fast rate in humans have a significant tendency to contain clusters of AT-to-GC (weak-to-strong biased substitutions. This pattern is also observed in noncoding sequence flanking rapidly evolving exons. Accelerated exons occur in regions with elevated male recombination rates and exhibit an excess of nonsynonymous substitutions relative to the genomic average. We next analyzed genes with significantly elevated ratios of nonsynonymous to synonymous rates of base substitution (dN/dS along the human lineage, and those with an excess of amino acid replacement substitutions relative to human polymorphism. These genes also show evidence of clusters of weak-to-strong biased substitutions. These findings indicate that a recombination-associated process, such as biased gene conversion (BGC, is driving fixation of GC alleles in the human genome. This process can lead to accelerated evolution in coding sequences and excess amino acid replacement substitutions, thereby generating significant results for tests of positive selection.

  4. Fast Noise Compensation and Adaptive Enhancement for Speech Separation

    Directory of Open Access Journals (Sweden)

    Hu Rong

    2008-01-01

    Full Text Available We propose a novel approach to improve adaptive decorrelation filtering- (ADF- based speech source separation in diffuse noise. The effects of noise on system adaptation and separation outputs are handled separately. First, fast noise compensation (NC is developed for adaptation of separation filters, forcing ADF to focus on source separation; next, output noises are suppressed by speech enhancement. By tracking noise components in output cross-correlation functions, the bias effect of noise on the system adaptation objective function is compensated, and by adaptively estimating output noise autocorrelations, the speech separation output is enhanced. For fast noise compensation, a blockwise fast ADF (FADF is implemented. Experiments were conducted on real and simulated diffuse noises. Speech mixtures were generated by convolving TIMIT speech sources with acoustic path impulse responses measured in a real room with reverberation time  second. The proposed techniques significantly improved separation performance and phone recognition accuracy of ADF outputs.

  5. Probability biases as Bayesian inference

    Directory of Open Access Journals (Sweden)

    Andre; C. R. Martins

    2006-11-01

    Full Text Available In this article, I will show how several observed biases in human probabilistic reasoning can be partially explained as good heuristics for making inferences in an environment where probabilities have uncertainties associated to them. Previous results show that the weight functions and the observed violations of coalescing and stochastic dominance can be understood from a Bayesian point of view. We will review those results and see that Bayesian methods should also be used as part of the explanation behind other known biases. That means that, although the observed errors are still errors under the be understood as adaptations to the solution of real life problems. Heuristics that allow fast evaluations and mimic a Bayesian inference would be an evolutionary advantage, since they would give us an efficient way of making decisions. %XX In that sense, it should be no surprise that humans reason with % probability as it has been observed.

  6. On commercial media bias

    OpenAIRE

    Germano, Fabrizio

    2008-01-01

    Within the spokes model of Chen and Riordan (2007) that allows for non-localized competition among arbitrary numbers of media outlets, we quantify the effect of concentration of ownership on quality and bias of media content. A main result shows that too few commercial outlets, or better, too few separate owners of commercial outlets can lead to substantial bias in equilibrium. Increasing the number of outlets (commercial and non-commercial) tends to bring down this bias; but the strong...

  7. Bias aware Kalman filters

    DEFF Research Database (Denmark)

    Drecourt, J.-P.; Madsen, H.; Rosbjerg, Dan

    2006-01-01

    This paper reviews two different approaches that have been proposed to tackle the problems of model bias with the Kalman filter: the use of a colored noise model and the implementation of a separate bias filter. Both filters are implemented with and without feedback of the bias into the model state...... are illustrated on a simple one-dimensional groundwater problem. The results show that the presented filters outperform the standard Kalman filter and that the implementations with bias feedback work in more general conditions than the implementations without feedback. 2005 Elsevier Ltd. All rights reserved....

  8. Interpretation biases in paranoia.

    Science.gov (United States)

    Savulich, George; Freeman, Daniel; Shergill, Sukhi; Yiend, Jenny

    2015-01-01

    Information in the environment is frequently ambiguous in meaning. Emotional ambiguity, such as the stare of a stranger, or the scream of a child, encompasses possible good or bad emotional consequences. Those with elevated vulnerability to affective disorders tend to interpret such material more negatively than those without, a phenomenon known as "negative interpretation bias." In this study we examined the relationship between vulnerability to psychosis, measured by trait paranoia, and interpretation bias. One set of material permitted broadly positive/negative (valenced) interpretations, while another allowed more or less paranoid interpretations, allowing us to also investigate the content specificity of interpretation biases associated with paranoia. Regression analyses (n=70) revealed that trait paranoia, trait anxiety, and cognitive inflexibility predicted paranoid interpretation bias, whereas trait anxiety and cognitive inflexibility predicted negative interpretation bias. In a group comparison those with high levels of trait paranoia were negatively biased in their interpretations of ambiguous information relative to those with low trait paranoia, and this effect was most pronounced for material directly related to paranoid concerns. Together these data suggest that a negative interpretation bias occurs in those with elevated vulnerability to paranoia, and that this bias may be strongest for material matching paranoid beliefs. We conclude that content-specific biases may be important in the cause and maintenance of paranoid symptoms.

  9. Political bias is tenacious.

    Science.gov (United States)

    Ditto, Peter H; Wojcik, Sean P; Chen, Eric Evan; Grady, Rebecca Hofstein; Ringel, Megan M

    2015-01-01

    Duarte et al. are right to worry about political bias in social psychology but they underestimate the ease of correcting it. Both liberals and conservatives show partisan bias that often worsens with cognitive sophistication. More non-liberals in social psychology is unlikely to speed our convergence upon the truth, although it may broaden the questions we ask and the data we collect.

  10. Phonon excitation and instabilities in biased graphene nanoconstrictions

    DEFF Research Database (Denmark)

    Gunst, Tue; Lu, Jing Tao; Hedegård, Per;

    2013-01-01

    We investigate how a high current density perturbs the phonons in a biased graphene nanoconstriction coupled to semi-infinite electrodes. The coupling to electrode phonons, electrode electrons under bias, Joule heating, and current-induced forces is evaluated using first principles density...

  11. Magnetization reversal in submicron disks: exchange biased vortices

    OpenAIRE

    Sort Viñas, Jordi; Hoffmann, Axel; Chung, S-H.; Buchanan, K. S.; Grimsditch, M.; Baró, M.D.; Dieny, B; Nogués i Sanmiquel, Josep

    2005-01-01

    Submicron, circular, ferromagnetic-antiferromagnetic dots exhibit different magnetization reversal mechanisms depending on the direction of the magnetic applied field. Shifted, constricted hysteresis loops, typical for vortex formation, are observed for fields along the exchange bias direction. However, for fields applied close to perpendicular to the exchange bias direction, magnetization reversal occurs via coherent rotation. Magnetic force microscopy imaging together with micromagnetic sim...

  12. Nanonet Force Microscopy for Measuring Cell Forces.

    Science.gov (United States)

    Sheets, Kevin; Wang, Ji; Zhao, Wei; Kapania, Rakesh; Nain, Amrinder S

    2016-07-12

    The influence of physical forces exerted by or felt by cells on cell shape, migration, and cytoskeleton arrangement is now widely acknowledged and hypothesized to occur due to modulation of cellular inside-out forces in response to changes in the external fibrous environment (outside-in). Our previous work using the non-electrospinning Spinneret-based Tunable Engineered Parameters' suspended fibers has revealed that cells are able to sense and respond to changes in fiber curvature and structural stiffness as evidenced by alterations to focal adhesion cluster lengths. Here, we present the development and application of a suspended nanonet platform for measuring C2C12 mouse myoblast forces attached to fibers of three diameters (250, 400, and 800 nm) representing a wide range of structural stiffness (3-50 nN/μm). The nanonet force microscopy platform measures cell adhesion forces in response to symmetric and asymmetric external perturbation in single and cyclic modes. We find that contractility-based, inside-out forces are evenly distributed at the edges of the cell, and that forces are dependent on fiber structural stiffness. Additionally, external perturbation in symmetric and asymmetric modes biases cell-fiber failure location without affecting the outside-in forces of cell-fiber adhesion. We then extend the platform to measure forces of (1) cell-cell junctions, (2) single cells undergoing cyclic perturbation in the presence of drugs, and (3) cancerous single-cells transitioning from a blebbing to a pseudopodial morphology. PMID:27410747

  13. Expectancy biases in fear and anxiety and their link to biases in attention.

    Science.gov (United States)

    Aue, Tatjana; Okon-Singer, Hadas

    2015-12-01

    Healthy individuals often exhibit prioritized processing of aversive information, as manifested in enhanced orientation of attention to threatening stimuli compared with neutral items. In contrast to this adaptive behavior, anxious, fearful, and phobic individuals show exaggerated attention biases to threat. In addition, they overestimate the likelihood of encountering their feared stimulus and the severity of the consequences; both are examples of expectancy biases. The co-occurrence of attention and expectancy biases in fear and anxiety raises the question about causal influences. Herein, we summarize findings related to expectancy biases in fear and anxiety, and their association with attention biases. We suggest that evidence calls for more comprehensive research strategies in the investigation of mutual influences between expectancy and attention biases, as well as their combined effects on fear and anxiety. Moreover, both types of bias need to be related to other types of distorted information processing commonly observed in fear and anxiety (e.g., memory and interpretation biases). Finally, we propose new research directions that may be worth considering in developing more effective treatments for anxiety disorders.

  14. Detection Biases in Bluffing

    OpenAIRE

    Holm, Håkan J.

    2008-01-01

    Beliefs in signals that reveal lies or truths are widespread. These signals may lead to a truth or lie detection bias if the probability that such a signal is perceived by the receiver is contingent on the truth value of the sender’s message. Such detection biases are analyzed theoretically in a bluffing game. The detection bias shrinks the equilibrium set to a unique non-pooling equilibrium, in which the better a player is at detecting lies the more often the opponent player will lie. With p...

  15. Simulating publication bias

    DEFF Research Database (Denmark)

    Paldam, Martin

    censoring: selection by the size of estimate; SR3 selects the optimal combination of fit and size; and SR4 selects the first satisficing result. The last four SRs are steered by priors and result in bias. The MST and the FAT-PET have been developed for detection and correction of such bias. The simulations...... are made by data variation, while the model is the same. It appears that SR0 generates narrow funnels much at odds with observed funnels, while the other four funnels look more realistic. SR1 to SR4 give the mean a substantial bias that confirms the prior causing the bias. The FAT-PET MRA works well...

  16. Introduction to Unconscious Bias

    Science.gov (United States)

    Schmelz, Joan T.

    2010-05-01

    We all have biases, and we are (for the most part) unaware of them. In general, men and women BOTH unconsciously devalue the contributions of women. This can have a detrimental effect on grant proposals, job applications, and performance reviews. Sociology is way ahead of astronomy in these studies. When evaluating identical application packages, male and female University psychology professors preferred 2:1 to hire "Brian” over "Karen” as an assistant professor. When evaluating a more experienced record (at the point of promotion to tenure), reservations were expressed four times more often when the name was female. This unconscious bias has a repeated negative effect on Karen's career. This talk will introduce the concept of unconscious bias and also give recommendations on how to address it using an example for a faculty search committee. The process of eliminating unconscious bias begins with awareness, then moves to policy and practice, and ends with accountability.

  17. Application and investigation of a bound for outcome reporting bias

    Directory of Open Access Journals (Sweden)

    Gamble Carrol

    2007-03-01

    Full Text Available Abstract Background Direct empirical evidence for the existence of outcome reporting bias is accumulating and this source of bias is recognised as a potential threat to the validity of meta-analysis of randomised clinical trials. Methods A method for calculating the maximum bias in a meta-analysis due to publication bias is adapted for the setting where within-study selective non-reporting of outcomes is suspected, and compared to the alternative approach of missing data imputation. The properties of both methods are investigated in realistic small sample situations. Results The results suggest that the adapted Copas and Jackson approach is the preferred method for reviewers to apply as an initial assessment of robustness to within-study selective non-reporting. Conclusion The Copas and Jackson approach is a useful method for systematic reviewers to apply to assess robustness to outcome reporting bias.

  18. Publication bias in situ

    Directory of Open Access Journals (Sweden)

    Phillips Carl V

    2004-08-01

    Full Text Available Abstract Background Publication bias, as typically defined, refers to the decreased likelihood of studies' results being published when they are near the null, not statistically significant, or otherwise "less interesting." But choices about how to analyze the data and which results to report create a publication bias within the published results, a bias I label "publication bias in situ" (PBIS. Discussion PBIS may create much greater bias in the literature than traditionally defined publication bias (the failure to publish any result from a study. The causes of PBIS are well known, consisting of various decisions about reporting that are influenced by the data. But its impact is not generally appreciated, and very little attention is devoted to it. What attention there is consists largely of rules for statistical analysis that are impractical and do not actually reduce the bias in reported estimates. PBIS cannot be reduced by statistical tools because it is not fundamentally a problem of statistics, but rather of non-statistical choices and plain language interpretations. PBIS should be recognized as a phenomenon worthy of study – it is extremely common and probably has a huge impact on results reported in the literature – and there should be greater systematic efforts to identify and reduce it. The paper presents examples, including results of a recent HIV vaccine trial, that show how easily PBIS can have a large impact on reported results, as well as how there can be no simple answer to it. Summary PBIS is a major problem, worthy of substantially more attention than it receives. There are ways to reduce the bias, but they are very seldom employed because they are largely unrecognized.

  19. Australia's Bond Home Bias

    OpenAIRE

    Mishra, Anil V; Umaru B. Conteh

    2014-01-01

    This paper constructs the float adjusted measure of home bias and explores the determinants of bond home bias by employing the International Monetary Fund's high quality dataset (2001 to 2009) on cross-border bond investment. The paper finds that Australian investors' prefer investing in countries with higher economic development and more developed bond markets. Exchange rate volatility appears to be an impediment for cross-border bond investment. Investors prefer investing in countries with ...

  20. Gender Bias in Tax Systems

    OpenAIRE

    Janet Gale Stotsky

    1996-01-01

    This paper examines the nature of gender bias in tax systems. Gender bias takes both explicit and implicit forms. Explicit gender bias is found in many personal income tax systems. Several countries, especially those in Western Europe, have undertaken to eliminate explicit gender bias in recent years. It is more difficult to identify implicit gender bias, since this depends in large part on value judgments as to desirable social and economic behavior. Implicit gender bias has also been a targ...

  1. Analysis of microstructural evolution driven by production bias

    DEFF Research Database (Denmark)

    Woo, C.H.; Semenov, A.A.; Singh, B.N.

    1993-01-01

    The concept of production bias was first considered in the preceding workshop in this series at Silkeborg in 1989. Since then, much work has been done to investigate the validity of the concept, and its usefulness in complementing the current theory of microstructure evolution based solely...... on the sink bias (e.g., dislocation bias) as a driving force. Comparison of the theory with experimental results clearly supports the concept. The present paper reviews and summarizes these investigations, and arrives at the following conclusions: a) the concept of production bias is consistent...

  2. Force Assignment of Radar Jamming System Based on Adaptive Genetic Algorithm%基于自适应遗传算法的雷达干扰系统兵力分配

    Institute of Scientific and Technical Information of China (English)

    潘伟

    2014-01-01

    The electronic jamming measures are used to decrease the detect ability of airborne ra-dar in air-raid combat. The jamming effectiveness is directly affected by the assignment of jam-ming force. According to the air-raid combat feature, a jamming force optimization apportion model is proposed based on an adaptive genetic algorithm. The adaptive crossover probability and adaptive mutation probability are proposed, which consider the influence of every generation to algorithm and the effect individual fitness in every generation. Finally, an example is given, which shows the feasibility of the proposed algorithm for handling the complicate and difficult problem of optimization apportion for jamming force.%在防空袭作战中,为了有效地降低敌机载雷达的探测能力,必须综合运用电子干扰措施实施电子干扰,干扰兵力分配直接影响干扰效果。结合防空袭作战的特点,提出了基于自适应遗传算法的雷达干扰系统兵力分配模型,并设计了既考虑到进化代数对算法影响,又考虑到每代中不同个体适应度对算法作用的自适应交叉概率和变异概率。仿真实例表明该方法可以有效解决雷达干扰系统兵力分配这一复杂而困难的问题。

  3. From effects-based operations to effects-based force : on causality, complex adaptive system and the the biology of war

    NARCIS (Netherlands)

    Jobbagy, Zoltán

    2009-01-01

    The author addresses a recent force employment concept called effects-based operations, which first appeared during the 1991 war against Iraq. The attributes of effects-based operations can be grouped around three common, but interrelated elements such as effects focus, advanced technology, and syst

  4. Nanoscopic oxidation of p-type and un-doped Si (100) surfaces using un-externally biased atomic force microscope tips (AFM) in the presence of selected organic solvents

    Science.gov (United States)

    McCausland, Jeffrey; Withanage, Sajeevi; Mallik, Robert; Lyuksyutov, Sergei

    A conductive un-biased AFM tip oscillating above p-type or un-doped Si (100) treated with toluene, butan-2-ol, and propan-2-ol creates nanostructures ranging in height from 1-100 nm. The tip was oscillated in ambient conditions (30-70% Rel. Humidity) at frequencies in the 102 kHz range. It was repeatable with various concentrations of solvent in aqueous solution. It is suggested that mechanical oscillations of the AFM tip polarizes the solvent molecules deposited on the surface resulting in electron transfer from the tip to the surface followed by feature formation. This process effectively creates an electrochemical cell at the microscopic level and the miscibility of the solvents is the key to enabling the process. Species which ionize during the process may be consumed in irreversible reactions whereas the alcohols act as catalysts and are not consumed. The influence of boron defects in the Si substrates is also discussed. It appears that the observed oxidation is different from all other similar reported phenomena including local anodic oxidation, and chemo-mechanical lithographic techniques utilizing AFM.

  5. Climate model bias correction and the role of timescales

    Directory of Open Access Journals (Sweden)

    J. O. Haerter

    2010-10-01

    Full Text Available It is well known that output from climate models cannot be used to force hydrological simulations without some form of preprocessing to remove the existing biases. In principle, statistical bias correction methodologies act on model output so the statistical properties of the corrected data match those of the observations. However the improvements to the statistical properties of the data are limited to the specific time scale of the fluctuations that are considered. For example, a statistical bias correction methodology for mean daily values might be detrimental to monthly statistics. Also, in applying bias corrections derived from present day to scenario simulations, an assumption is made of persistence of the bias over the largest timescales. We examine the effects of mixing fluctuations on different time scales and suggest an improved statistical methodology, referred to here as a cascade bias correction method, that eliminates, or greatly reduces, the negative effects.

  6. Measuring Agricultural Bias

    DEFF Research Database (Denmark)

    Jensen, Henning Tarp; Robinson, Sherman; Tarp, Finn

    The measurement issue is the key issue in the literature on trade policy-induced agri-cultural price incentive bias. This paper introduces a general equilibrium effective rate of protection (GE-ERP) measure, which extends and generalizes earlier partial equilibrium nominal protection measures....... For the 15 sample countries, the results indicate that the agricultural price incentive bias, which was generally perceived to exist during the 1980s, was largely eliminated during the 1990s. The results also demonstrate that general equilibrium effects and country-specific characteristics - including trade...... shares and intersectoral linkages - are crucial for determining the sign and magnitude of trade policy bias. The GE-ERP measure is therefore uniquely suited to capture the full impact of trade policies on agricultural price incentives. A Monte Carlo procedure confirms that the results are robust...

  7. Velocity bias in a LCDM model

    CERN Document Server

    Colin, Pierre; Kravtsov, A V; Colin, Pedro; Klypin, Anatoly; Kravtsov, Andrey V.

    2000-01-01

    We use N-body simulations to study the velocity bias of dark matter halos, the difference in the velocity fields of dark matter and halos, in a flat low- density LCDM model. The high force, 2kpc/h, and mass, 10^9Msun/h, resolution allows dark matter halos to survive in very dense environments of groups and clusters making it possible to use halos as galaxy tracers. We find that the velocity bias pvb measured as a ratio of pairwise velocities of the halos to that of the dark matter evolves with time and depends on scale. At high redshifts (z ~5) halos move generally faster than the dark matter almost on all scales: pvb(r)~1.2, r>0.5Mpc/h. At later moments the bias decreases and gets below unity on scales less than r=5Mpc/h: pvb(r)~(0.6-0.8) at z=0. We find that the evolution of the pairwise velocity bias follows and probably is defined by the spatial antibias of the dark matter halos at small scales. One-point velocity bias b_v, defined as the ratio of the rms velocities of halos and dark matter, provides a mo...

  8. Electrostatically biased binding of kinesin to microtubules.

    Directory of Open Access Journals (Sweden)

    Barry J Grant

    2011-11-01

    Full Text Available The minimum motor domain of kinesin-1 is a single head. Recent evidence suggests that such minimal motor domains generate force by a biased binding mechanism, in which they preferentially select binding sites on the microtubule that lie ahead in the progress direction of the motor. A specific molecular mechanism for biased binding has, however, so far been lacking. Here we use atomistic Brownian dynamics simulations combined with experimental mutagenesis to show that incoming kinesin heads undergo electrostatically guided diffusion-to-capture by microtubules, and that this produces directionally biased binding. Kinesin-1 heads are initially rotated by the electrostatic field so that their tubulin-binding sites face inwards, and then steered towards a plus-endwards binding site. In tethered kinesin dimers, this bias is amplified. A 3-residue sequence (RAK in kinesin helix alpha-6 is predicted to be important for electrostatic guidance. Real-world mutagenesis of this sequence powerfully influences kinesin-driven microtubule sliding, with one mutant producing a 5-fold acceleration over wild type. We conclude that electrostatic interactions play an important role in the kinesin stepping mechanism, by biasing the diffusional association of kinesin with microtubules.

  9. Contextual modulation of biases in face recognition.

    Directory of Open Access Journals (Sweden)

    Fatima Maria Felisberti

    Full Text Available BACKGROUND: The ability to recognize the faces of potential cooperators and cheaters is fundamental to social exchanges, given that cooperation for mutual benefit is expected. Studies addressing biases in face recognition have so far proved inconclusive, with reports of biases towards faces of cheaters, biases towards faces of cooperators, or no biases at all. This study attempts to uncover possible causes underlying such discrepancies. METHODOLOGY AND FINDINGS: Four experiments were designed to investigate biases in face recognition during social exchanges when behavioral descriptors (prosocial, antisocial or neutral embedded in different scenarios were tagged to faces during memorization. Face recognition, measured as accuracy and response latency, was tested with modified yes-no, forced-choice and recall tasks (N = 174. An enhanced recognition of faces tagged with prosocial descriptors was observed when the encoding scenario involved financial transactions and the rules of the social contract were not explicit (experiments 1 and 2. Such bias was eliminated or attenuated by making participants explicitly aware of "cooperative", "cheating" and "neutral/indifferent" behaviors via a pre-test questionnaire and then adding such tags to behavioral descriptors (experiment 3. Further, in a social judgment scenario with descriptors of salient moral behaviors, recognition of antisocial and prosocial faces was similar, but significantly better than neutral faces (experiment 4. CONCLUSION: The results highlight the relevance of descriptors and scenarios of social exchange in face recognition, when the frequency of prosocial and antisocial individuals in a group is similar. Recognition biases towards prosocial faces emerged when descriptors did not state the rules of a social contract or the moral status of a behavior, and they point to the existence of broad and flexible cognitive abilities finely tuned to minor changes in social context.

  10. Measuring agricultural policy bias

    DEFF Research Database (Denmark)

    Jensen, Henning Tarp; Robinson, Sherman; Tarp, Finn

    2010-01-01

    Measurement is a key issue in the literature on price incentive bias induced by trade policy. We introduce a general equilibrium measure of the relative effective rate of protection, which generalizes earlier protection measures. For our fifteen sample countries, results indicate...... protection measure is therefore uniquely suited to capture the full impact of trade policies on relative agricultural price incentives....

  11. Prolonged performance of a high repetition low force task induces bone adaptation in young adult rats, but loss in mature rats.

    Science.gov (United States)

    Massicotte, Vicky S; Frara, Nagat; Harris, Michele Y; Amin, Mamta; Wade, Christine K; Popoff, Steven N; Barbe, Mary F

    2015-12-01

    We have shown that prolonged repetitive reaching and grasping tasks lead to exposure-dependent changes in bone microarchitecture and inflammatory cytokines in young adult rats. Since aging mammals show increased tissue inflammatory cytokines, we sought here to determine if aging, combined with prolonged performance of a repetitive upper extremity task, enhances bone loss. We examined the radius, forearm flexor muscles, and serum from 16 mature (14-18 months of age) and 14 young adult (2.5-6.5 months of age) female rats after performance of a high repetition low force (HRLF) reaching and grasping task for 12 weeks. Young adult HRLF rats showed enhanced radial bone growth (e.g., increased trabecular bone volume, osteoblast numbers, bone formation rate, and mid-diaphyseal periosteal perimeter), compared to age-matched controls. Mature HRLF rats showed several indices of radial bone loss (e.g., decreased trabecular bone volume, and increased cortical bone thinning, porosity, resorptive spaces and woven bone formation), increased osteoclast numbers and inflammatory cytokines, compared to age-matched controls and young adult HRLF rats. Mature rats weighed more yet had lower maximum reflexive grip strength, than young adult rats, although each age group was able to pull at the required reach rate (4 reaches/min) and required submaximal pulling force (30 force-grams) for a food reward. Serum estrogen levels and flexor digitorum muscle size were similar in each age group. Thus, mature rats had increased bone degradative changes than in young adult rats performing the same repetitive task for 12 weeks, with increased inflammatory cytokine responses and osteoclast activity as possible causes.

  12. A New Bias Corrected Version of Heteroscedasticity Consistent Covariance Estimator

    Directory of Open Access Journals (Sweden)

    Munir Ahmed

    2016-06-01

    Full Text Available In the presence of heteroscedasticity, different available flavours of the heteroscedasticity consistent covariance estimator (HCCME are used. However, the available literature shows that these estimators can be considerably biased in small samples. Cribari–Neto et al. (2000 introduce a bias adjustment mechanism and give the modified White estimator that becomes almost bias-free even in small samples. Extending these results, Cribari-Neto and Galvão (2003 present a similar bias adjustment mechanism that can be applied to a wide class of HCCMEs’. In the present article, we follow the same mechanism as proposed by Cribari-Neto and Galvão to give bias-correction version of HCCME but we use adaptive HCCME rather than the conventional HCCME. The Monte Carlo study is used to evaluate the performance of our proposed estimators.

  13. Temperature trend biases

    Science.gov (United States)

    Venema, Victor; Lindau, Ralf

    2016-04-01

    In an accompanying talk we show that well-homogenized national dataset warm more than temperatures from global collections averaged over the region of common coverage. In this poster we want to present auxiliary work about possible biases in the raw observations and on how well relative statistical homogenization can remove trend biases. There are several possible causes of cooling biases, which have not been studied much. Siting could be an important factor. Urban stations tend to move away from the centre to better locations. Many stations started inside of urban areas and are nowadays more outside. Even for villages the temperature difference between the centre and edge can be 0.5°C. When a city station moves to an airport, which often happened around WWII, this takes the station (largely) out of the urban heat island. During the 20th century the Stevenson screen was established as the dominant thermometer screen. This screen protected the thermometer much better against radiation than earlier designs. Deficits of earlier measurement methods have artificially warmed the temperatures in the 19th century. Newer studies suggest we may have underestimated the size of this bias. Currently we are in a transition to Automatic Weather Stations. The net global effect of this transition is not clear at this moment. Irrigation on average decreases the 2m-temperature by about 1 degree centigrade. At the same time, irrigation has increased significantly during the last century. People preferentially live in irrigated areas and weather stations serve agriculture. Thus it is possible that there is a higher likelihood that weather stations are erected in irrigated areas than elsewhere. In this case irrigation could lead to a spurious cooling trend. In the Parallel Observations Science Team of the International Surface Temperature Initiative (ISTI-POST) we are studying influence of the introduction of Stevenson screens and Automatic Weather Stations using parallel measurements

  14. Adaptive designs for sequential experiments

    Institute of Scientific and Technical Information of China (English)

    林正炎; 张立新

    2003-01-01

    Various adaptive designs have been proposed and applied to clinical trials, bioassay, psychophysics, etc.Adaptive designs are also useful in high cost engineering trials.More and more people have been paying attention to these design methods. This paper introduces several broad families of designs, such as the play-the-winner rule, randomized play-the-winner rule and its generalization to the multi-arm case, doubly biased coin adaptive design, Markov chain model.

  15. Sensitivity of hydrologic simulations to bias corrected driving parameters

    Science.gov (United States)

    Papadimitriou, Lamprini; Grillakis, Manolis; Koutroulis, Aristeidis; Tsanis, Ioannis

    2016-04-01

    Climate model outputs feature systematic errors and biases that render them unsuitable for direct use by the impact models. To deal with this issue many bias correction techniques have been developed to adjust the modelled variables against observations. For the most common applications adjustment concerns only precipitation and temperature whilst for others all the driving parameters (including radiation, wind speed, humidity, air pressure) are bias adjusted. Bias adjusting only part of the variables required as biophysical model input could affect the physical consistency among input variables and is poorly studied. It is important to determine and quantify the effect that bias adjusting each climate variable has on the impact model's simulation and identify parameters that could be treated as raw outputs for specific model applications. In this work, the sensitivity of climate simulations to bias adjusted driving parameters is tested by conducting a series of model runs, for which the impact model JULES is forced with: i) not bias corrected input variables, ii) all bias corrected input variables, iii-viii) all input variables bias corrected except for: iii) precipitation, iv) temperature, v) radiation, vi) specific humidity, vii) air pressure and viii) wind speed. This set of runs is conducted for three climate models of different equilibrium climate sensitivity: GFDL-ESM2M, MIROC-ESM-CHEM and IPSL-CM5A-LR. The baseline for the comparison of the experimental runs is a JULES run forced with the WFDEI dataset, the dataset that was used as the observational dataset for adjusting biases. The comparative analysis is performed using the time period 1981-2010 and focusing on output variables of the hydrological cycle (runoff, evapotranspiration, soil moisture).

  16. Assessing Bias in Search Engines.

    Science.gov (United States)

    Mowshowitz, Abbe; Kawaguchi, Akira

    2002-01-01

    Addresses the measurement of bias in search engines on the Web, defining bias as the balance and representation of items in a collection retrieved from a database for a set of queries. Assesses bias by measuring the deviation from the ideal of the distribution produced by a particular search engine. (Author/LRW)

  17. Experience of the air medical evacuation team of Serbian armed forces in the united nations mission in the Democratic Republic of Congo - deployment stress and psychological adaptation

    Directory of Open Access Journals (Sweden)

    Joković Danilo B.

    2016-01-01

    Full Text Available Background/Aim. Wars of the nineties in former Yugoslavia, Somalia, Rwanda imposed new tasks to the United Nations (UN forces, such as providing humanitarian aid, protection of civilians, peacekeeping, and in many instances providing armed enforcement of peace. The aim of this study was an observational analysis of Serbian participation in the UNs Mission in the Democratic Republic of Congo with the emphasis on stress and coping techniques. Methods. Serbian contribution in this mission dates back to April 2003 till the present days with a military contingent consisting of six members as a part of Air Medical Evacuation Team. The observed stressogenous factors acted before arrival to the mission area and in the mission area. In this paper we analysed ways to overcome them. Results. The productive ways of overwhelming stress used in this mission were: honesty and openness in interpersonal communications, dedication to work, maintaining discipline and order, strict following of appropriate regime of work, diet, rest and recreation; regular communication with family and organizing and participation in various social, cultural and sports manifestations. Conclusion. This analysis indicates that out of all the observed factors, the most important is appropriate selection of personnel.

  18. Test Bias and the Elimination of Racism

    Science.gov (United States)

    Sedlacek, William E.

    1977-01-01

    Three types of test bias are discussed: content bias, atmosphere bias, and use bias. Use bias is considered the most important. Tests reflect the bias in society, and eliminating test bias means eliminating racism and sexism in society. A six-stage model to eliminate racism and sexism is presented. (Author)

  19. Two success-biased social learning strategies.

    Science.gov (United States)

    Baldini, Ryan

    2013-06-01

    I compare the evolutionary dynamics of two success-biased social learning strategies, which, by definition, use the success of others to inform one's social learning decisions. The first, "Compare Means", causes a learner to adopt cultural variants with highest mean payoff in her sample. The second, "Imitate the Best", causes a learner to imitate the single most successful individual in her sample. I summarize conditions under which each strategy performs well or poorly, and investigate their evolution via a gene-culture coevolutionary model. Despite the adaptive appeal of these strategies, both encounter conditions under which they systematically perform worse than simply imitating at random. Compare Means performs worst when the optimal cultural variant is usually at high frequency, while Imitate the Best performs worst when suboptimal variants sometimes produce high payoffs. The extent to which it is optimal to use success-biased social learning depends strongly on the payoff distributions and environmental conditions that human social learners face.

  20. Visuomotor Adaptation: How Forgetting Keeps Us Conservative

    NARCIS (Netherlands)

    Kooij, K. van der; Brenner, E.M.; Beers, R.J. van; Smeets, J.B.J.

    2015-01-01

    Even when provided with feedback after every movement, adaptation levels off before biases are completely removed. Incomplete adaptation has recently been attributed to forgetting: the adaptation is already partially forgotten by the time the next movement is made. Here we test whether this idea is

  1. Adaptation and perceptual norms

    Science.gov (United States)

    Webster, Michael A.; Yasuda, Maiko; Haber, Sara; Leonard, Deanne; Ballardini, Nicole

    2007-02-01

    We used adaptation to examine the relationship between perceptual norms--the stimuli observers describe as psychologically neutral, and response norms--the stimulus levels that leave visual sensitivity in a neutral or balanced state. Adapting to stimuli on opposite sides of a neutral point (e.g. redder or greener than white) biases appearance in opposite ways. Thus the adapting stimulus can be titrated to find the unique adapting level that does not bias appearance. We compared these response norms to subjectively defined neutral points both within the same observer (at different retinal eccentricities) and between observers. These comparisons were made for visual judgments of color, image focus, and human faces, stimuli that are very different and may depend on very different levels of processing, yet which share the property that for each there is a well defined and perceptually salient norm. In each case the adaptation aftereffects were consistent with an underlying sensitivity basis for the perceptual norm. Specifically, response norms were similar to and thus covaried with the perceptual norm, and under common adaptation differences between subjectively defined norms were reduced. These results are consistent with models of norm-based codes and suggest that these codes underlie an important link between visual coding and visual experience.

  2. Arc force self-adapt control system of invert arc welding machine%逆变弧焊机电弧推力自适应控制系统

    Institute of Scientific and Technical Information of China (English)

    朱志明; 罗小锋; 吴文楷

    2001-01-01

    When welding current is fixed,some important information such as length and section area of welding cable,connection of ground wire can be shown by output voltage of instantaneous arc-striking.The arc force self-adapt control system of invert arc welding machine is based on single-chip micro-processor MC68HC11.First,detecting the output voltage of arc-striking in the real-time,the arc force voltage can be auto-adjusted along with the ch anging of the length and section area of welding cable.Then inspecting welding v oltage in the real-time and controlling welding current by fuzzy process, there fore the arc force control of manual metal arc welding is provided with powe rful self-adaptability.%在焊接电流确定的条件下,引弧瞬间的焊机输出电压反映了焊接电缆长度、截面积以及地线连接情况等重要信息。本研究装置是基于MC68HC11单片机控制的逆变焊机电弧推力自适应控制系统,首先通过对引弧瞬间焊机输出电压的实时检测,实现了电弧推力拐点电压随焊接电流及焊接电缆长度、截面积等改变而自动调节;然后通过对焊接电弧电压的实时检测与模糊处理控制焊机的输出电流,从而使MMA手工电弧焊的电弧推力控制具有很强的自适应能力。

  3. The Dynamic Force Table

    Science.gov (United States)

    Geddes, John B.; Black, Kelly

    2008-01-01

    We examine an experimental apparatus that is used to motivate the connections between the basic properties of vectors, potential functions, systems of nonlinear equations, and Newton's method for nonlinear systems of equations. The apparatus is an adaptation of a force table where we remove the center-pin and allow the center-ring to move freely.…

  4. Abundance of female-biased and paucity of male-biased somatically expressed genes on the mouse X-chromosome

    Directory of Open Access Journals (Sweden)

    Reinius Björn

    2012-11-01

    Full Text Available Abstract Background Empirical evaluations of sexually dimorphic expression of genes on the mammalian X-chromosome are needed to understand the evolutionary forces and the gene-regulatory mechanisms controlling this chromosome. We performed a large-scale sex-bias expression analysis of genes on the X-chromosome in six different somatic tissues from mouse. Results Our results show that the mouse X-chromosome is enriched with female-biased genes and depleted of male-biased genes. This suggests that feminisation as well as de-masculinisation of the X-chromosome has occurred in terms of gene expression in non-reproductive tissues. Several mechanisms may be responsible for the control of female-biased expression on chromosome X, and escape from X-inactivation is a main candidate. We confirmed escape in case of Tmem29 using RNA-FISH analysis. In addition, we identified novel female-biased non-coding transcripts located in the same female-biased cluster as the well-known coding X-inactivation escapee Kdm5c, likely transcribed from the transition-region between active and silenced domains. We also found that previously known escapees only partially explained the overrepresentation of female-biased X-genes, particularly for tissue-specific female-biased genes. Therefore, the gene set we have identified contains tissue-specific escapees and/or genes controlled by other sexually skewed regulatory mechanisms. Analysis of gene age showed that evolutionarily old X-genes (>100 myr, preceding the radiation of placental mammals are more frequently female-biased than younger genes. Conclusion Altogether, our results have implications for understanding both gene regulation and gene evolution of mammalian X-chromosomes, and suggest that the final result in terms of the X-gene composition (masculinisation versus feminisation is a compromise between different evolutionary forces acting on reproductive and somatic tissues.

  5. Measuring nonlocal Lagrangian peak bias

    CERN Document Server

    Biagetti, Matteo; Desjacques, Vincent; Paranjape, Aseem

    2013-01-01

    In the Lagrangian approach to halo clustering, nonlocal bias can be generated either in the initial conditions or by the subsequent gravitational motions. Here, we investigate nonlocal Lagrangian bias contributions involving gradients of the linear density field, for which we have predictions from the excursion set peak formalism. We reformulate this approach in order to explicitly take into account the variable describing the crossing of the collapse barrier. This enables us to write down a bias expansion which includes all the bias terms, including the nonlocal ones. Having checked that the model furnishes a reasonable fit to the halo mass function, we extend the 1-point cross-correlation technique of Musso, Paranjape & Sheth (2012) to bias contributions that are chi-squared distributed. We validate the method with numerical realizations of peaks of Gaussian random fields before applying it to N-body simulations. We focus on the lowest (quadratic) order nonlocal bias factors predicted by the excursion s...

  6. Theoretical investigation of exchange bias

    Institute of Scientific and Technical Information of China (English)

    Xiong Zhi-Jie; Wang Huai-Yu; Ding Ze-Jun

    2007-01-01

    The exchange bias of bilayer magnetic films consisting of ferromagnetic (FM) and antiferromagnetic (AFM) layers in an uncompensated case is studied by use of the many-body Green's function method of quantum statistical theory.The effects of the layer thickness and temperature and the interfacial coupling strength on the exchange bias HE are investigated. The dependence of the exchange bias HE on the FM layer thickness and temperature is qualitatively in agreement with experimental results. When temperature varies, both the coercivity HC and HE decrease with the temperature increasing. For each FM thickness, there exists a least AFM thickness in which the exchange bias occurs,which is called pinning thickness.

  7. Influence of SST biases on future climate change projections

    Energy Technology Data Exchange (ETDEWEB)

    Ashfaq, Moetasim [Stanford University, Department of Environmental Earth System Science, Stanford, CA (United States); Purdue University, Department of Earth and Atmospheric Sciences, West Lafayette, IN (United States); Climate Change Science Institute, Oak Ridge National Laboratory, Oak Ridge, TN (United States); Skinner, Christopher B. [Stanford University, Department of Environmental Earth System Science, Stanford, CA (United States); Purdue University, Department of Earth and Atmospheric Sciences, West Lafayette, IN (United States); Diffenbaugh, Noah S. [Stanford University, Department of Environmental Earth System Science, Stanford, CA (United States); Purdue University, Department of Earth and Atmospheric Sciences, West Lafayette, IN (United States); Stanford University, Woods Institute for the Environment, Stanford, CA (United States)

    2011-04-15

    We use a quantile-based bias correction technique and a multi-member ensemble of the atmospheric component of NCAR CCSM3 (CAM3) simulations to investigate the influence of sea surface temperature (SST) biases on future climate change projections. The simulations, which cover 1977-1999 in the historical period and 2077-2099 in the future (A1B) period, use the CCSM3-generated SSTs as prescribed boundary conditions. Bias correction is applied to the monthly time-series of SSTs so that the simulated changes in SST mean and variability are preserved. Our comparison of CAM3 simulations with and without SST correction shows that the SST biases affect the precipitation distribution in CAM3 over many regions by introducing errors in atmospheric moisture content and upper-level (lower-level) divergence (convergence). Also, bias correction leads to significantly different precipitation and surface temperature changes over many oceanic and terrestrial regions (predominantly in the tropics) in response to the future anthropogenic increases in greenhouse forcing. The differences in the precipitation response from SST bias correction occur both in the mean and the percent change, and are independent of the ocean-atmosphere coupling. Many of these differences are comparable to or larger than the spread of future precipitation changes across the CMIP3 ensemble. Such biases can affect the simulated terrestrial feedbacks and thermohaline circulations in coupled climate model integrations through changes in the hydrological cycle and ocean salinity. Moreover, biases in CCSM3-generated SSTs are generally similar to the biases in CMIP3 ensemble mean SSTs, suggesting that other GCMs may display a similar sensitivity of projected climate change to SST errors. These results help to quantify the influence of climate model biases on the simulated climate change, and therefore should inform the effort to further develop approaches for reliable climate change projection. (orig.)

  8. Fast Noise Compensation and Adaptive Enhancement for Speech Separation

    Directory of Open Access Journals (Sweden)

    Yunxin Zhao

    2008-07-01

    Full Text Available We propose a novel approach to improve adaptive decorrelation filtering- (ADF- based speech source separation in diffuse noise. The effects of noise on system adaptation and separation outputs are handled separately. First, fast noise compensation (NC is developed for adaptation of separation filters, forcing ADF to focus on source separation; next, output noises are suppressed by speech enhancement. By tracking noise components in output cross-correlation functions, the bias effect of noise on the system adaptation objective function is compensated, and by adaptively estimating output noise autocorrelations, the speech separation output is enhanced. For fast noise compensation, a blockwise fast ADF (FADF is implemented. Experiments were conducted on real and simulated diffuse noises. Speech mixtures were generated by convolving TIMIT speech sources with acoustic path impulse responses measured in a real room with reverberation time T60=0.3 second. The proposed techniques significantly improved separation performance and phone recognition accuracy of ADF outputs.

  9. Information environment, behavioral biases, and home bias in analysts’ recommendations

    DEFF Research Database (Denmark)

    Farooq, Omar; Taouss, Mohammed

    2012-01-01

    Can information environment of a firm explain home bias in analysts’ recommendations? Can the extent of agency problems explain optimism difference between foreign and local analysts? This paper answers these questions by documenting the effect of information environment on home bias in analysts’...

  10. First priciples simulations of a bias-dependent electrochemical cell

    CERN Document Server

    Pedroza, Luana S; Rocha, Alexandre Reily; Fernández-Serra, Marivi

    2016-01-01

    Understanding the local structure of liquid water at the interfaces of metallic electrodes is a key problem in aqueous-based electrochemistry. Notably the system is under an external potential bias, which makes the task of simulating this setup difficult. To correctly compute the effect of an external bias potential applied to electrodes, we combine density functional theory and non-equilibrium Green's functions methods. Our method now allows to explicitly consider an external applied bias, in direct correspondence to the experiments. In this work, we apply this methodology to study the electronic properties and atomic forces of one water molecule at the interface of gold electrodes. We find that, as expected, the water molecule is sensitive to the sign and magnitude of the applied bias.

  11. Visuomotor Adaptation: How Forgetting Keeps Us Conservative

    OpenAIRE

    Katinka van der Kooij; Eli Brenner; van Beers, Robert J; Smeets, Jeroen B.J.

    2015-01-01

    Even when provided with feedback after every movement, adaptation levels off before biases are completely removed. Incomplete adaptation has recently been attributed to forgetting: the adaptation is already partially forgotten by the time the next movement is made. Here we test whether this idea is correct. If so, the final level of adaptation is determined by a balance between learning and forgetting. Because we learn from perceived errors, scaling these errors by a magnification factor has ...

  12. Labor Force

    Science.gov (United States)

    Occupational Outlook Quarterly, 2012

    2012-01-01

    The labor force is the number of people ages 16 or older who are either working or looking for work. It does not include active-duty military personnel or the institutionalized population, such as prison inmates. Determining the size of the labor force is a way of determining how big the economy can get. The size of the labor force depends on two…

  13. Facing the partner influences exchanges in force

    Science.gov (United States)

    Takagi, Atsushi; Bagnato, Carlo; Burdet, Etienne

    2016-01-01

    Many studies in psychology have documented how the behaviour of verbally communicating pairs is affected by social factors such as the partner’s gaze. However, few studies have examined whether physically interacting pairs are influenced by social factors. Here, we asked two partners to exchange forces with one another, where the goal was to accurately replicate the force back onto the other. We first measured an individual’s accuracy in reproducing a force from a robot. We then tested pairs who knowingly exchanged forces whilst separated by a curtain. These separated pairs exchanged forces as two independent individuals would, hence the force reproduction accuracy of partners is not affected by knowingly reproducing a force onto a nonvisible partner. On the other hand, pairs who exchanged forces whilst facing one another consistently under-reproduced the partner’s force in comparison to separated partners. Thus, the force reproduction accuracy of subjects is strongly biased by facing a partner. PMID:27739492

  14. Bootstrap Co-integration Rank Testing: The Effect of Bias-Correcting Parameter Estimates

    OpenAIRE

    Cavaliere, Giuseppe; Taylor, A. M. Robert; Trenkler, Carsten

    2013-01-01

    In this paper we investigate bootstrap-based methods for bias-correcting the first-stage parameter estimates used in some recently developed bootstrap implementations of the co-integration rank tests of Johansen (1996). In order to do so we adapt the framework of Kilian (1998) which estimates the bias in the original parameter estimates using the average bias in the corresponding parameter esti- mates taken across a large number of auxiliary bootstrap replications. A number of possible imp...

  15. On ribosome load, codon bias and protein abundance.

    Directory of Open Access Journals (Sweden)

    Stefan Klumpp

    Full Text Available Different codons encoding the same amino acid are not used equally in protein-coding sequences. In bacteria, there is a bias towards codons with high translation rates. This bias is most pronounced in highly expressed proteins, but a recent study of synthetic GFP-coding sequences did not find a correlation between codon usage and GFP expression, suggesting that such correlation in natural sequences is not a simple property of translational mechanisms. Here, we investigate the effect of evolutionary forces on codon usage. The relation between codon bias and protein abundance is quantitatively analyzed based on the hypothesis that codon bias evolved to ensure the efficient usage of ribosomes, a precious commodity for fast growing cells. An explicit fitness landscape is formulated based on bacterial growth laws to relate protein abundance and ribosomal load. The model leads to a quantitative relation between codon bias and protein abundance, which accounts for a substantial part of the observed bias for E. coli. Moreover, by providing an evolutionary link, the ribosome load model resolves the apparent conflict between the observed relation of protein abundance and codon bias in natural sequences and the lack of such dependence in a synthetic gfp library. Finally, we show that the relation between codon usage and protein abundance can be used to predict protein abundance from genomic sequence data alone without adjustable parameters.

  16. Bias in clinical intervention research

    DEFF Research Database (Denmark)

    Gluud, Lise Lotte

    2006-01-01

    Research on bias in clinical trials may help identify some of the reasons why investigators sometimes reach the wrong conclusions about intervention effects. Several quality components for the assessment of bias control have been suggested, but although they seem intrinsically valid, empirical...

  17. Face Adaptation Without a Face

    OpenAIRE

    Ghuman, Avniel Singh; McDaniel, Jonathan R.; Martin, Alex

    2010-01-01

    Prolonged viewing of a stimulus results in a subsequent perceptual bias [1], [2] and [3]. This perceptual adaptation and the resulting aftereffect reveal important characteristics regarding how perceptual systems are tuned [2], [4], [5] and [6]. These aftereffects occur not only for simple stimulus features but also for high-level stimulus properties [7], [8], [9] and [10]. Here we report a novel cross-category adaptation aftereffect demonstrating that prolonged viewing of a human body withou...

  18. Propagation of biases in humidity in the estimation of global irrigation water

    Directory of Open Access Journals (Sweden)

    Y. Masaki

    2015-07-01

    Although different GHMs have different sensitivities to atmospheric humidity because different types of potential evapotranspiration formulae are implemented in them, bias correction of the humidity should be applied to forcing data, particularly for the evaluation of evapotranspiration and irrigation water.

  19. Bias Errors in Measurement of Vibratory Power and Implication for Active Control of Structural Vibration

    DEFF Research Database (Denmark)

    Ohlrich, Mogens; Henriksen, Eigil; Laugesen, Søren

    1997-01-01

    Uncertainties in power measurements performed with piezoelectric accelerometers and force transducers are investigated. It is shown that the inherent structural damping of the transducers is responsible for a bias phase error, which typically is in the order of one degree. Fortunately, such bias......, and the limitations imposed in active control of structural vibration based upon a strategy of power minimisation....

  20. Finding the most biased coin with fewest flips

    CERN Document Server

    Chandrasekaran, Karthekeyan

    2012-01-01

    We study the problem of learning the most biased coin among a set of coins by tossing the coins adaptively. The goal is to minimize the number of tosses to identify a coin i* such that prob{coin i* is most biased} is at least 1-\\delta\\ for any given \\delta>0. Under a particular probabilistic model, we give an optimal algorithm, i.e., an algorithm that minimizes the expected number of tosses, to learn a most biased coin. The problem is equivalent to finding the best arm in the multi-armed bandit problem using adaptive strategies. Dar et al. (2002) and Mannor and Tsitsiklis (2004) show upper and lower bounds matching up to constant factors on the number of coin tosses for several underlying settings of the bias probabilities. For a class of such settings we bridge the constant factor gap by giving an optimal adaptive strategy -- a strategy that performs the best possible action under any given history of outcomes. For any given history, tossing the coin chosen by our strategy minimizes the expected number of to...

  1. The Evolution of Rotation Group Bias: Will the Real Unemployment Rate Please Stand Up?

    OpenAIRE

    Alan B. Krueger; Mas, Alexandre; Niu, Xiaotong

    2014-01-01

    This paper documents that rotation group bias -- the tendency for labor force statistics to vary systematically by month in sample in labor force surveys -- in the Current Population Survey (CPS) has worsened considerably over time. The estimated unemployment rate for earlier rotation groups has grown sharply relative to the unemployment rate for later rotation groups; both should be nationally representative samples. The rise in rotation group bias is driven by a growing tendency for respond...

  2. Force sensing

    OpenAIRE

    Sanders, David

    2007-01-01

    A young child can explore and learn and compensate for unknown dynamics by prodding, pushing, touching, grasping and feeling. Force sensing and software research could soon allow artificial mechanisms to do the same. Force sensing has its roots in strain gauges, piezoelectrics, Wheatstone bridges, automation, robotics, grippers and virtual reality. That force sensing research has now become commonplace and has expanded from those roots to include so much more: video games, athletic equipment,...

  3. Administrative bias in South Africa

    Directory of Open Access Journals (Sweden)

    E S Nwauche

    2005-01-01

    Full Text Available This article reviews the interpretation of section 6(2(aii of the Promotion of Administrative Justice Act which makes an administrator “biased or reasonably suspected of bias” a ground of judicial review. In this regard, the paper reviews the determination of administrative bias in South Africa especially highlighting the concept of institutional bias. The paper notes that inspite of the formulation of the bias ground of review the test for administrative bias is the reasonable apprehension test laid down in the case of President of South Africa v South African Rugby Football Union(2 which on close examination is not the same thing. Accordingly the paper urges an alternative interpretation that is based on the reasonable suspicion test enunciated in BTR Industries South Africa (Pty Ltd v Metal and Allied Workers Union and R v Roberts. Within this context, the paper constructs a model for interpreting the bias ground of review that combines the reasonable suspicion test as interpreted in BTR Industries and R v Roberts, the possibility of the waiver of administrative bias, the curative mechanism of administrative appeal as well as some level of judicial review exemplified by the jurisprudence of article 6(1 of the European Convention of Human Rights, especially in the light of the contemplation of the South African Magistrate Court as a jurisdictional route of judicial review.

  4. Cognitive Bias in Systems Verification

    Science.gov (United States)

    Larson, Steve

    2012-01-01

    Working definition of cognitive bias: Patterns by which information is sought and interpreted that can lead to systematic errors in decisions. Cognitive bias is used in diverse fields: Economics, Politics, Intelligence, Marketing, to name a few. Attempts to ground cognitive science in physical characteristics of the cognitive apparatus exceed our knowledge. Studies based on correlations; strict cause and effect is difficult to pinpoint. Effects cited in the paper and discussed here have been replicated many times over, and appear sound. Many biases have been described, but it is still unclear whether they are all distinct. There may only be a handful of fundamental biases, which manifest in various ways. Bias can effect system verification in many ways . Overconfidence -> Questionable decisions to deploy. Availability -> Inability to conceive critical tests. Representativeness -> Overinterpretation of results. Positive Test Strategies -> Confirmation bias. Debiasing at individual level very difficult. The potential effect of bias on the verification process can be managed, but not eliminated. Worth considering at key points in the process.

  5. Codon Adaptation of Plastid Genes

    Science.gov (United States)

    Suzuki, Haruo; Morton, Brian R.

    2016-01-01

    Codon adaptation is codon usage bias that results from selective pressure to increase the translation efficiency of a gene. Codon adaptation has been studied across a wide range of genomes and some early analyses of plastids have shown evidence for codon adaptation in a limited set of highly expressed plastid genes. Here we study codon usage bias across all fully sequenced plastid genomes which includes representatives of the Rhodophyta, Alveolata, Cryptophyta, Euglenozoa, Glaucocystophyceae, Rhizaria, Stramenopiles and numerous lineages within the Viridiplantae, including Chlorophyta and Embryophyta. We show evidence that codon adaptation occurs in all genomes except for two, Theileria parva and Heicosporidium sp., both of which have highly reduced gene contents and no photosynthesis genes. We also show evidence that selection for codon adaptation increases the representation of the same set of codons, which we refer to as the adaptive codons, across this wide range of taxa, which is probably due to common features descended from the initial endosymbiont. We use various measures to estimate the relative strength of selection in the different lineages and show that it appears to be fairly strong in certain Stramenopiles and Chlorophyta lineages but relatively weak in many members of the Rhodophyta, Euglenozoa and Embryophyta. Given these results we propose that codon adaptation in plastids is widespread and displays the same general features as adaptation in eubacterial genomes. PMID:27196606

  6. Codon Adaptation of Plastid Genes.

    Directory of Open Access Journals (Sweden)

    Haruo Suzuki

    Full Text Available Codon adaptation is codon usage bias that results from selective pressure to increase the translation efficiency of a gene. Codon adaptation has been studied across a wide range of genomes and some early analyses of plastids have shown evidence for codon adaptation in a limited set of highly expressed plastid genes. Here we study codon usage bias across all fully sequenced plastid genomes which includes representatives of the Rhodophyta, Alveolata, Cryptophyta, Euglenozoa, Glaucocystophyceae, Rhizaria, Stramenopiles and numerous lineages within the Viridiplantae, including Chlorophyta and Embryophyta. We show evidence that codon adaptation occurs in all genomes except for two, Theileria parva and Heicosporidium sp., both of which have highly reduced gene contents and no photosynthesis genes. We also show evidence that selection for codon adaptation increases the representation of the same set of codons, which we refer to as the adaptive codons, across this wide range of taxa, which is probably due to common features descended from the initial endosymbiont. We use various measures to estimate the relative strength of selection in the different lineages and show that it appears to be fairly strong in certain Stramenopiles and Chlorophyta lineages but relatively weak in many members of the Rhodophyta, Euglenozoa and Embryophyta. Given these results we propose that codon adaptation in plastids is widespread and displays the same general features as adaptation in eubacterial genomes.

  7. Multi-Directional Motion Adaptation

    Directory of Open Access Journals (Sweden)

    David Patrick McGovern

    2012-05-01

    Full Text Available The direction aftereffect (DAE is a phenomenon whereby prolonged exposure to a moving stimulus biases the perceived direction of subsequent stimuli. It is believed to arise through a selective suppression of directionally tuned neurons in the visual cortex, causing shifts in the population response away from the adapted direction. Whereas most studies consider only unidirectional adaptation, here we examine how concurrent adaptation to multiple directions affects the DAE. Observers were required to judge whether a random dot kinematogram (RDK moved clockwise or counter-clockwise relative to upwards. In different conditions, observers adapted to a stimulus comprised of directions drawn from a distribution or to bidirectional motion. Increasing the variance of normally distributed directions reduced the magnitude of the peak DAE and broadened its tuning profile. Asymmetric sampling of Gaussian and uniform distributions resulted in shifts of DAE tuning profiles consistent with changes in the perceived global direction of the adapting stimulus. Discrimination thresholds were elevated by an amount that related to the magnitude of the bias. For bidirectional adaptors, adding dots in directions away from the adapting motion led to a pronounced reduction in the DAE. This reduction was observed when dots were added in opposite or orthogonal directions to the adaptor suggesting that it may arise via inhibition from a broadly tuned normalisation pool. Preliminary simulations with a population coding model, where the gain of a direction-selective neuron is inversely proportional to its response to the adapting stimulus, suggest that it provides a parsimonious account of these adaptation effects.

  8. Codon Adaptation of Plastid Genes.

    Science.gov (United States)

    Suzuki, Haruo; Morton, Brian R

    2016-01-01

    Codon adaptation is codon usage bias that results from selective pressure to increase the translation efficiency of a gene. Codon adaptation has been studied across a wide range of genomes and some early analyses of plastids have shown evidence for codon adaptation in a limited set of highly expressed plastid genes. Here we study codon usage bias across all fully sequenced plastid genomes which includes representatives of the Rhodophyta, Alveolata, Cryptophyta, Euglenozoa, Glaucocystophyceae, Rhizaria, Stramenopiles and numerous lineages within the Viridiplantae, including Chlorophyta and Embryophyta. We show evidence that codon adaptation occurs in all genomes except for two, Theileria parva and Heicosporidium sp., both of which have highly reduced gene contents and no photosynthesis genes. We also show evidence that selection for codon adaptation increases the representation of the same set of codons, which we refer to as the adaptive codons, across this wide range of taxa, which is probably due to common features descended from the initial endosymbiont. We use various measures to estimate the relative strength of selection in the different lineages and show that it appears to be fairly strong in certain Stramenopiles and Chlorophyta lineages but relatively weak in many members of the Rhodophyta, Euglenozoa and Embryophyta. Given these results we propose that codon adaptation in plastids is widespread and displays the same general features as adaptation in eubacterial genomes. PMID:27196606

  9. Biased Reasoning : Adaptive Responses to Health Risk Feedback

    OpenAIRE

    Renner, Britta

    2004-01-01

    The present study examined reactions toward repeated self relevant feedback. Participants in a community health screening received feedback about their cholesterol level on two separate occasions. Reactions to the first feedback were examined with regard to feedback valence and expectedness. The findings showed that negative feedback was devalued, but only when it was unexpected. Feedback consistency war incorporated into analyses of the second feedback. Again, results showed that negative fe...

  10. Hybrid position/force control of a constrained manipulator using adaptive wavelet sliding mode%受限机械臂的自适应小波滑模位置/力混合控制

    Institute of Scientific and Technical Information of China (English)

    周芳; 朱齐丹; 姜迈; 汪瞳

    2009-01-01

    针对终端运动受约束的机械臂位置/力混合控制问题,提出了一种自适应小波滑模控制算法.该控制方案将滑模控制的鲁棒性及自适应调整能力与小波神经网络相结合,根据坐标变换得到降阶位置/力模型,针对降阶模型采用小波神经网络在线学习系统未知动力学模型中的非线性部分,同时引入滑模控制自动调整小波网络权值参数,从而对神经网络的固有逼近误差进行有效补偿,达到期望的跟踪性能.二自由度机械臂的仿真结果表明该控制器能保证系统快速有效跟踪指定参考信号.%The hybrid position/force control of the robotic manipulator whose motion was constrained in the end was discussed. An adaptive wavelet sling mode control strategy was proposed, in which in-tegrating the robustness and self-adjustment advantages of sliding mode control were integrated into the wavelet network controller. A reduced position/force model was obtained according to the nonlinear translation, a wavelet network was used to learn the unknown nonlinear dynamic of system. Sim-ultaneous, the sliding mode technique was designed such that the wavelet weighted parameters could be automatically tuned thereby compensating the approximate error of the wavelet network in order to obtain the desired tracking performances. Simulation results of two-degree of freedom manipulator show the designed controller ensures the system track the desired reference signals quickly and efficiency.

  11. Gender bias in academic recruitment

    DEFF Research Database (Denmark)

    Abramo, Giovanni; D’Angelo, Ciriaco Andrea; Rosati, Francesco

    2016-01-01

    It is well known that women are underrepresented in the academic systems of many countries. Gender discrimination is one of the factors that could contribute to this phenomenon. This study considers a recent national academic recruitment campaign in Italy, examining whether women are subject...... to more or less bias than men. The findings show that no gender-related differences occur among the candidates who benefit from positive bias, while among those candidates affected by negative bias, the incidence of women is lower than that of men. Among the factors that determine success in a competition...

  12. Strong Force

    CERN Multimedia

    Without the strong force, there could be no life. The carbon in living matter is synthesised in stars via the strong force. Lighter atomic nuclei become bound together in a process called nuclear fusion. A minor change in this interaction would make life impossible. As its name suggests, the strong force is the most powerful of the 4 forces, yet its sphere of influence is limited to within the atomic nucleus. Indeed it is the strong force that holds together the quarks inside the positively charged protons. Without this glue, the quarks would fly apart repulsed by electromagnetism. In fact, it is impossible to separate 2 quarks : so much energy is needed, that a second pair of quarks is produced. Text for the interactive: Can you pull apart the quarks inside a proton?

  13. Preferences, country bias, and international trade

    NARCIS (Netherlands)

    S. Roy (Santanu); J.M.A. Viaene (Jean-Marie)

    1998-01-01

    textabstractAnalyzes international trade where consumer preferences exhibit country bias. Why country biases arise; How trade can occur in the presence of country bias; Implication for the pattern of trade and specialization.

  14. Adaptive designs for sequential experiments

    Institute of Scientific and Technical Information of China (English)

    林正炎; 张立新

    2003-01-01

    Various adaptive designe have been proposed and applied to clinical trials,bioassay,psycho-physics,etc.Adaptive designs are also useful in high cost engineering trials.More and More people have been paying attention to these desing methods.This paper introduces several broad families of designs,such as the play-the-winner rele,randomized play-the-winner rule and its generalization to the multi-arm case,doubly bi-ased coin adaptive design,Markov chain model.

  15. The intentionality bias and schizotypy

    OpenAIRE

    Moore, James W.; Pope, A.

    2014-01-01

    The “intentionality bias” refers to our automatic tendency to judge other people's actions to be intentional. In this experiment we extended research on this effect in two key ways. First, we developed a novel nonlinguistic task for assessing the intentionality bias. This task used video stimuli of ambiguous movements. Second, we investigated the relationship between the strength of this bias and schizotypy (schizophrenia-like symptoms in healthy individuals). Our results showed that the inte...

  16. The estimation method of GPS instrumental biases

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A model of estimating the global positioning system (GPS) instrumental biases and the methods to calculate the relative instrumental biases of satellite and receiver are presented. The calculated results of GPS instrumental biases, the relative instrumental biases of satellite and receiver, and total electron content (TEC) are also shown. Finally, the stability of GPS instrumental biases as well as that of satellite and receiver instrumental biases are evaluated, indicating that they are very stable during a period of two months and a half.

  17. Weak Force

    CERN Multimedia

    Without the weak force, the sun wouldn't shine. The weak force causes beta decay, a form of radioactivity that triggers nuclear fusion in the heart of the sun. The weak force is unlike other forces: it is characterised by disintegration. In beta decay, a down quark transforms into an up quark and an electron is emitted. Some materials are more radioactive than others because the delicate balance between the strong force and the weak force varies depending on the number of particles in the atomic nucleus. We live in the midst of a natural radioactive background that varies from region to region. For example, in Cornwall where there is a lot of granite, levels of background radiation are much higher than in the Geneva region. Text for the interactive: Move the Geiger counter to find out which samples are radioactive - you may be surprised. It is the weak force that is responsible for the Beta radioactivity here. The electrons emitted do not cross the plastic cover. Why do you think there is some detected radioa...

  18. Bias and design in software specifications

    Science.gov (United States)

    Straub, Pablo A.; Zelkowitz, Marvin V.

    1990-01-01

    Implementation bias in a specification is an arbitrary constraint in the solution space. Presented here is a model of bias in software specifications. Bias is defined in terms of the specification process and a classification of the attributes of the software product. Our definition of bias provides insight into both the origin and the consequences of bias. It also shows that bias is relative and essentially unavoidable. Finally, we describe current work on defining a measure of bias, formalizing our model, and relating bias to software defects.

  19. Adaptive Lighting

    OpenAIRE

    Petersen, Kjell Yngve; Søndergaard, Karin; Kongshaug, Jesper

    2015-01-01

    Adaptive LightingAdaptive lighting is based on a partial automation of the possibilities to adjust the colour tone and brightness levels of light in order to adapt to people’s needs and desires. IT support is key to the technical developments that afford adaptive control systems. The possibilities offered by adaptive lighting control are created by the ways that the system components, the network and data flow can be coordinated through software so that the dynamic variations are controlled i...

  20. Biased feedback in brain-computer interfaces

    Directory of Open Access Journals (Sweden)

    Barbero Álvaro

    2010-07-01

    Full Text Available Abstract Even though feedback is considered to play an important role in learning how to operate a brain-computer interface (BCI, to date no significant influence of feedback design on BCI-performance has been reported in literature. In this work, we adapt a standard motor-imagery BCI-paradigm to study how BCI-performance is affected by biasing the belief subjects have on their level of control over the BCI system. Our findings indicate that subjects already capable of operating a BCI are impeded by inaccurate feedback, while subjects normally performing on or close to chance level may actually benefit from an incorrect belief on their performance level. Our results imply that optimal feedback design in BCIs should take into account a subject's current skill level.

  1. SYRCLE's risk of bias tool for animal studies

    OpenAIRE

    C R Hooijmans; Rovers, M M; Vries, R.B.M. de; Leenaars, M.; Ritskes-Hoitinga, M.; Langendam, M.W.

    2014-01-01

    BACKGROUND: Systematic Reviews (SRs) of experimental animal studies are not yet common practice, but awareness of the merits of conducting such SRs is steadily increasing. As animal intervention studies differ from randomized clinical trials (RCT) in many aspects, the methodology for SRs of clinical trials needs to be adapted and optimized for animal intervention studies. The Cochrane Collaboration developed a Risk of Bias (RoB) tool to establish consistency and avoid discrepancies in assessi...

  2. Biases in probabilistic category learning in relation to social anxiety

    OpenAIRE

    Abraham, Anna; Hermann, Christiane

    2015-01-01

    Instrumental learning paradigms are rarely employed to investigate the mechanisms underlying acquired fear responses in social anxiety. Here, we adapted a probabilistic category learning paradigm to assess information processing biases as a function of the degree of social anxiety traits in a sample of healthy individuals without a diagnosis of social phobia. Participants were presented with three pairs of neutral faces with differing probabilistic accuracy contingencies (A/B: 80/20, C/D: 70/...

  3. Error signals driving locomotor adaptation

    DEFF Research Database (Denmark)

    Choi, Julia T; Jensen, Peter; Nielsen, Jens Bo;

    2016-01-01

    perturbations. Forces were applied to the ankle joint during the early swing phase using an electrohydraulic ankle-foot orthosis. Repetitive 80 Hz electrical stimulation was applied to disrupt cutaneous feedback from the superficial peroneal nerve (foot dorsum) and medial plantar nerve (foot sole) during...... walking (Choi et al. 2013). Sensory tests were performed to measure cutaneous touch threshold and perceptual threshold of force perturbations. Ankle movement were measured while subjects walked on the treadmill over three periods: baseline (1 min), adaptation (1 min) and post-adaptation (3 min). Subjects...... (n = 10) showed increased touch thresholds measured with Von Frey monofilaments and increased force perception thresholds with stimulation. Stimulation reduced the magnitude of walking adaptation to force perturbation. In addition, we compared the effects of interrupting cutaneous feedback using...

  4. Measurement Bias Detection through Factor Analysis

    Science.gov (United States)

    Barendse, M. T.; Oort, F. J.; Werner, C. S.; Ligtvoet, R.; Schermelleh-Engel, K.

    2012-01-01

    Measurement bias is defined as a violation of measurement invariance, which can be investigated through multigroup factor analysis (MGFA), by testing across-group differences in intercepts (uniform bias) and factor loadings (nonuniform bias). Restricted factor analysis (RFA) can also be used to detect measurement bias. To also enable nonuniform…

  5. Comparative Analysis of Codon Usage Bias Patterns in Microsporidian Genomes

    OpenAIRE

    Xiang, Heng; Zhang, Ruizhi; Butler, Robert R.; Liu, Tie; Zhang, Li; Pombert, Jean-François; Zhou, Zeyang

    2015-01-01

    The sub-3 Mbp genomes from microsporidian species of the Encephalitozoon genus are the smallest known among eukaryotes and paragons of genomic reduction and compaction in parasites. However, their diminutive stature is not characteristic of all Microsporidia, whose genome sizes vary by an order of magnitude. This large variability suggests that different evolutionary forces are applied on the group as a whole. In this study, we have compared the codon usage bias (CUB) between eight taxonomica...

  6. Bias in Dynamic Monte Carlo Alpha Calculations

    Energy Technology Data Exchange (ETDEWEB)

    Sweezy, Jeremy Ed [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nolen, Steven Douglas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Adams, Terry R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Trahan, Travis John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-02-06

    A 1/N bias in the estimate of the neutron time-constant (commonly denoted as α) has been seen in dynamic neutronic calculations performed with MCATK. In this paper we show that the bias is most likely caused by taking the logarithm of a stochastic quantity. We also investigate the known bias due to the particle population control method used in MCATK. We conclude that this bias due to the particle population control method is negligible compared to other sources of bias.

  7. A review on biological adaptation: with applications in engineering science

    Directory of Open Access Journals (Sweden)

    LiMin Luo

    2014-06-01

    Full Text Available Biological adaptation refers to that organisms change themselves at morphological, physiological, behavioral and molecular level to better survive in a changing environment. It includes phenotype adaptation and molecular adaptation. Biological adaptation is a driving force of evolution. Biological adaptation was described from Darwinian theory of evolution to the theory of molecular evolution in present paper. Adaptive control and adaptive filtering were briefly described also.

  8. Minimum Bias Trigger in ATLAS

    International Nuclear Information System (INIS)

    Since the restart of the LHC in November 2009, ATLAS has collected inelastic pp collisions to perform first measurements on charged particle densities. These measurements will help to constrain various models describing phenomenologically soft parton interactions. Understanding the trigger efficiencies for different event types are therefore crucial to minimize any possible bias in the event selection. ATLAS uses two main minimum bias triggers, featuring complementary detector components and trigger levels. While a hardware based first trigger level situated in the forward regions with 2.2 < |η| < 3.8 has been proven to select pp-collisions very efficiently, the Inner Detector based minimum bias trigger uses a random seed on filled bunches and central tracking detectors for the event selection. Both triggers were essential for the analysis of kinematic spectra of charged particles. Their performance and trigger efficiency measurements as well as studies on possible bias sources will be presented. We also highlight the advantage of these triggers for particle correlation analyses. (author)

  9. Perception bias in route choice

    NARCIS (Netherlands)

    Vreeswijk, J.D.; Thomas, T.; Berkum, van E.C.; Arem, van B.

    2014-01-01

    Travel time is probably one of the most studied attributes in route choice. Recently, perception of travel time received more attention as several studies have shown its importance in explaining route choice behavior. In particular, travel time estimates by travelers appear to be biased against non-

  10. Microturbulence measurements during divertor biasing

    International Nuclear Information System (INIS)

    The application of a bias voltage to a neutralization plate of the upper divertor with respect to the vacuum chamber in the Tokamak de Varennes (TdeV) influences the plasma well inside the separatrix. In particular, the unbiased Ohmic poloidal rotation edge velocity measured by visible spectroscopy is found to be in the electron diamagnetic drift direction (2-3 km/s) and increases by a factor of two for Vbias = 100 V. This coincides with a major reduction of the microturbulence signal at low frequencies (50 kHz -1 -1), as determined from coherent laser scattering measurements. One possible explanation is that the turbulence signal is simply Doppler shifted to frequencies outside the accessible range. This scenario is, however, difficult to reconcile with some observations. Another explanation invokes a reduction of the turbulence level. The variation of the turbulence signal as a function of the applied bias voltage can indeed be reproduced with a theoretical model based on radial and poloidal decorrelation mechanisms, the latter corresponding to poloidal velocity shear stabilization. This model also explains the observed steepening of the k-spectrum decay during biasing. Biasing also modifies the electron density profile inside the separatrix. These changes of nabla ne cannot explain the behaviour of microturbulence behaviour, when explained in terms of stabilization, would agree with the plasma maintaining a steeper electron density gradient. (author). 17 refs, 9 figs

  11. Attentional bias in math anxiety

    Science.gov (United States)

    Rubinsten, Orly; Eidlin, Hili; Wohl, Hadas; Akibli, Orly

    2015-01-01

    Cognitive theory from the field of general anxiety suggests that the tendency to display attentional bias toward negative information results in anxiety. Accordingly, the current study aims to investigate whether attentional bias is involved in math anxiety (MA) as well (i.e., a persistent negative reaction to math). Twenty seven participants (14 with high levels of MA and 13 with low levels of MA) were presented with a novel computerized numerical version of the well established dot probe task. One of six types of prime stimuli, either math related or typically neutral, was presented on one side of a computer screen. The prime was preceded by a probe (either one or two asterisks) that appeared in either the prime or the opposite location. Participants had to discriminate probe identity (one or two asterisks). Math anxious individuals reacted faster when the probe was at the location of the numerical related stimuli. This suggests the existence of attentional bias in MA. That is, for math anxious individuals, the cognitive system selectively favored the processing of emotionally negative information (i.e., math related words). These findings suggest that attentional bias is linked to unduly intense MA symptoms. PMID:26528208

  12. Attentional Bias in Math Anxiety

    Directory of Open Access Journals (Sweden)

    Orly eRubinsten

    2015-10-01

    Full Text Available Cognitive theory from the field of general anxiety suggests that the tendency to display attentional bias toward negative information results in anxiety. Accordingly, the current study aims to investigate whether attentional bias is involved in math anxiety as well (i.e., a persistent negative reaction to math. Twenty seven participants (14 with high levels of math anxiety and 13 with low levels of math anxiety were presented with a novel computerized numerical version of the well established dot probe task. One of 6 types of prime stimuli, either math related or typically neutral, were presented on one side of a computer screen. The prime was preceded by a probe (either one or two asterisks that appeared in either the prime or the opposite location. Participants had to discriminate probe identity (one or two asterisks. Math anxious individuals reacted faster when the probe was at the location of the numerical related stimuli. This suggests the existence of attentional bias in math anxiety. That is, for math anxious individuals, the cognitive system selectively favored the processing of emotionally negative information (i.e., math related words. These findings suggest that attentional bias is linked to unduly intense math anxiety symptoms.

  13. Stereotype Formation : Biased by Association

    NARCIS (Netherlands)

    Le Pelley, Mike E.; Reimers, Stian J.; Calvini, Guglielmo; Spears, Russell; Beesley, Tom; Murphy, Robin A.

    2010-01-01

    We propose that biases in attitude and stereotype formation might arise as a result of learned differences ill the extent its which social groups have previously been predictive elf behavioral or physical properties Experiments 1 and 2 demonstrate that differences in the experienced predictiveness o

  14. Attentional bias in math anxiety.

    Science.gov (United States)

    Rubinsten, Orly; Eidlin, Hili; Wohl, Hadas; Akibli, Orly

    2015-01-01

    Cognitive theory from the field of general anxiety suggests that the tendency to display attentional bias toward negative information results in anxiety. Accordingly, the current study aims to investigate whether attentional bias is involved in math anxiety (MA) as well (i.e., a persistent negative reaction to math). Twenty seven participants (14 with high levels of MA and 13 with low levels of MA) were presented with a novel computerized numerical version of the well established dot probe task. One of six types of prime stimuli, either math related or typically neutral, was presented on one side of a computer screen. The prime was preceded by a probe (either one or two asterisks) that appeared in either the prime or the opposite location. Participants had to discriminate probe identity (one or two asterisks). Math anxious individuals reacted faster when the probe was at the location of the numerical related stimuli. This suggests the existence of attentional bias in MA. That is, for math anxious individuals, the cognitive system selectively favored the processing of emotionally negative information (i.e., math related words). These findings suggest that attentional bias is linked to unduly intense MA symptoms.

  15. Adaptive Lighting

    DEFF Research Database (Denmark)

    Petersen, Kjell Yngve; Søndergaard, Karin; Kongshaug, Jesper

    2015-01-01

    Adaptive Lighting Adaptive lighting is based on a partial automation of the possibilities to adjust the colour tone and brightness levels of light in order to adapt to people’s needs and desires. IT support is key to the technical developments that afford adaptive control systems. The possibilities...... offered by adaptive lighting control are created by the ways that the system components, the network and data flow can be coordinated through software so that the dynamic variations are controlled in ways that meaningfully adapt according to people’s situations and design intentions. This book discusses...... distributed differently into an architectural body. We also examine what might occur when light is dynamic and able to change colour, intensity and direction, and when it is adaptive and can be brought into interaction with its surroundings. In short, what happens to an architectural space when artificial...

  16. Bias Adjusted Precipitation Threat Scores

    Directory of Open Access Journals (Sweden)

    F. Mesinger

    2008-04-01

    Full Text Available Among the wide variety of performance measures available for the assessment of skill of deterministic precipitation forecasts, the equitable threat score (ETS might well be the one used most frequently. It is typically used in conjunction with the bias score. However, apart from its mathematical definition the meaning of the ETS is not clear. It has been pointed out (Mason, 1989; Hamill, 1999 that forecasts with a larger bias tend to have a higher ETS. Even so, the present author has not seen this having been accounted for in any of numerous papers that in recent years have used the ETS along with bias "as a measure of forecast accuracy".

    A method to adjust the threat score (TS or the ETS so as to arrive at their values that correspond to unit bias in order to show the model's or forecaster's accuracy in extit{placing} precipitation has been proposed earlier by the present author (Mesinger and Brill, the so-called dH/dF method. A serious deficiency however has since been noted with the dH/dF method in that the hypothetical function that it arrives at to interpolate or extrapolate the observed value of hits to unit bias can have values of hits greater than forecast when the forecast area tends to zero. Another method is proposed here based on the assumption that the increase in hits per unit increase in false alarms is proportional to the yet unhit area. This new method removes the deficiency of the dH/dF method. Examples of its performance for 12 months of forecasts by three NCEP operational models are given.

  17. Optimal Design of Large Dimensional Adaptive Subspace Detectors

    KAUST Repository

    Ben Atitallah, Ismail

    2016-05-27

    This paper addresses the design of Adaptive Subspace Matched Filter (ASMF) detectors in the presence of a mismatch in the steering vector. These detectors are coined as adaptive in reference to the step of utilizing an estimate of the clutter covariance matrix using training data of signalfree observations. To estimate the clutter covariance matrix, we employ regularized covariance estimators that, by construction, force the eigenvalues of the covariance estimates to be greater than a positive scalar . While this feature is likely to increase the bias of the covariance estimate, it presents the advantage of improving its conditioning, thus making the regularization suitable for handling high dimensional regimes. In this paper, we consider the setting of the regularization parameter and the threshold for ASMF detectors in both Gaussian and Compound Gaussian clutters. In order to allow for a proper selection of these parameters, it is essential to analyze the false alarm and detection probabilities. For tractability, such a task is carried out under the asymptotic regime in which the number of observations and their dimensions grow simultaneously large, thereby allowing us to leverage existing results from random matrix theory. Simulation results are provided in order to illustrate the relevance of the proposed design strategy and to compare the performances of the proposed ASMF detectors versus Adaptive normalized Matched Filter (ANMF) detectors under mismatch scenarios.

  18. Discharge simulations performed with a hydrological model using bias corrected regional climate model input

    Directory of Open Access Journals (Sweden)

    S. C. van Pelt

    2009-12-01

    Full Text Available Studies have demonstrated that precipitation on Northern Hemisphere mid-latitudes has increased in the last decades and that it is likely that this trend will continue. This will have an influence on discharge of the river Meuse. The use of bias correction methods is important when the effect of precipitation change on river discharge is studied. The objective of this paper is to investigate the effect of using two different bias correction methods on output from a Regional Climate Model (RCM simulation. In this study a Regional Atmospheric Climate Model (RACMO2 run is used, forced by ECHAM5/MPIOM under the condition of the SRES-A1B emission scenario, with a 25 km horizontal resolution. The RACMO2 runs contain a systematic precipitation bias on which two bias correction methods are applied. The first method corrects for the wet day fraction and wet day average (WD bias correction and the second method corrects for the mean and coefficient of variance (MV bias correction. The WD bias correction initially corrects well for the average, but it appears that too many successive precipitation days were removed with this correction. The second method performed less well on average bias correction, but the temporal precipitation pattern was better. Subsequently, the discharge was calculated by using RACMO2 output as forcing to the HBV-96 hydrological model. A large difference was found between the simulated discharge of the uncorrected RACMO2 run, the WD bias corrected run and the MV bias corrected run. These results show the importance of an appropriate bias correction.

  19. Discharge simulations performed with a hydrological model using bias corrected regional climate model input

    Directory of Open Access Journals (Sweden)

    S. C. van Pelt

    2009-06-01

    Full Text Available Studies have demonstrated that precipitation on Northern Hemisphere mid-latitudes has increased in the last decades and that it is likely that this trend will continue. This will have an influence on discharge of the river Meuse. The use of bias correction methods is important when the effect of precipitation change on river discharge is studied. The objective of this paper is to investigate the effect of using two different bias correction methods on output from a Regional Climate Model (RCM simulation. In this study a Regional Atmospheric Climate Model (RACMO2 run is used, forced by ECHAM-5 under the condition of the SRES-A1B emission scenario, with a 25 km horizontal resolution. The RACMO2 runs contain a systematic precipitation bias on which two bias correction methods are applied. The first method corrects for the wet day fraction and wet day average (WD bias correction and the second method corrects for the mean and coefficient of variance (MV bias correction. The WD bias correction initially corrects well for the average, but it appears that too many successive precipitation days were removed with this correction. The second method performed less well on average bias correction, but the temporal precipitation pattern was better. Subsequently, the discharge was calculated by using RACMO2 output as forcing to the HBV-96 hydrological model. A large difference was found between the simulated discharge of the uncorrected RACMO2 run, the WD bias corrected run and the MV bias corrected run. These results show the importance of an appropriate bias correction.

  20. Sensorimotor memory biases weight perception during object lifting

    Directory of Open Access Journals (Sweden)

    Vonne evan Polanen

    2015-12-01

    Full Text Available When lifting an object, the brain uses visual cues and an internal object representation to predict its weight and scale fingertip forces accordingly. Once available, tactile information is rapidly integrated to update the weight prediction and refine the internal object representation. If visual cues cannot be used to predict weight, force planning relies on implicit knowledge acquired from recent lifting experience, termed sensorimotor memory. Here, we investigated whether perception of weight is similarly biased according to previous lifting experience and how this is related to force scaling. Participants grasped and lifted series of light or heavy objects in a semi-randomized order and estimated their weights. As expected, we found that forces were scaled based on previous lifts (sensorimotor memory and these effects increased depending on the length of recent lifting experience. Importantly, perceptual weight estimates were also influenced by the preceding lift, resulting in lower estimations after a heavy lift compared to a light one. In addition, the weight estimations were negatively correlated with the magnitude of planned force parameters. This perceptual bias was only found if the current lift was light, but not heavy since the magnitude of sensorimotor memory effects had, according to Weber’s law, relatively less impact on heavy compared to light objects. A control experiment tested the importance of active lifting in mediating these perceptual changes and showed that when weights are passively applied on the hand, no effect of previous sensory experience is found on perception. These results highlight how fast learning of novel object lifting dynamics can shape weight perception and demonstrate a tight link between action planning and perception control. If predictive force scaling and actual object weight do not match, the online motor corrections, rapidly implemented to downscale forces, will also downscale weight estimation in

  1. Automated Monte Carlo biasing for photon-generated electrons near surfaces.

    Energy Technology Data Exchange (ETDEWEB)

    Franke, Brian Claude; Crawford, Martin James; Kensek, Ronald Patrick

    2009-09-01

    This report describes efforts to automate the biasing of coupled electron-photon Monte Carlo particle transport calculations. The approach was based on weight-windows biasing. Weight-window settings were determined using adjoint-flux Monte Carlo calculations. A variety of algorithms were investigated for adaptivity of the Monte Carlo tallies. Tree data structures were used to investigate spatial partitioning. Functional-expansion tallies were used to investigate higher-order spatial representations.

  2. Adaptive Lighting

    DEFF Research Database (Denmark)

    Petersen, Kjell Yngve; Søndergaard, Karin; Kongshaug, Jesper

    2015-01-01

    Adaptive Lighting Adaptive lighting is based on a partial automation of the possibilities to adjust the colour tone and brightness levels of light in order to adapt to people’s needs and desires. IT support is key to the technical developments that afford adaptive control systems. The possibilities...... offered by adaptive lighting control are created by the ways that the system components, the network and data flow can be coordinated through software so that the dynamic variations are controlled in ways that meaningfully adapt according to people’s situations and design intentions. This book discusses...... the investigations of lighting scenarios carried out in two test installations: White Cube and White Box. The test installations are discussed as large-scale experiential instruments. In these test installations we examine what could potentially occur when light using LED technology is integrated and...

  3. Belief bias and relational reasoning.

    Science.gov (United States)

    Roberts, Maxwell J; Sykes, Elizabeth D A

    2003-01-01

    When people evaluate categorical syllogisms, they tend to reject unbelievable conclusions and accept believable ones irrespective of their validity. Typically, this effect is particularly marked for invalid conclusions that are possible, but do not necessarily follow, given the premises. However, smaller believability effects can also be detected for other types of conclusion. Three experiments are reported here, in which an attempt was made to determine whether belief bias effects can manifest themselves on the relational inference task. Subjects evaluated the validity of conclusions such as William the Conqueror was king after the Pyramids were built (temporal task) or Manchester is north of Bournemouth (spatial task) with respect to their premises. All of the major findings for equivalent categorical syllogism tasks were replicated. However, the overall size of the main effect of believability appears to be related to task presentation, a phenomenon not previously identified for categorical syllogisms and which current theories of belief bias have difficulty explaining.

  4. A quantum exchange bias model

    International Nuclear Information System (INIS)

    The origin of the exchange bias phenomenon is investigated on the basis of a quantum mechanical model. In particular, the mechanisms that determine the magnetic structure in the vicinity of an antiferromagnetic-ferromagnetic interface are reexamined. This way we establish how the breaking of translational invariance modifies quantum spin fluctuations. It is found that non-uniform fluctuations induce uncompensated spins in the antiferromagnet, which in turn give rise to a dipole field that couples to the magnetization of the ferromagnet. This coupling yields an exchange bias field that is of the order of magnitude of the one observed experimentally. A net surface magnetization should also be experimentally observable in a clean antiferromagnetic surface

  5. Opinion Dynamics with Confirmation Bias

    CERN Document Server

    Allahverdyan, A E

    2014-01-01

    Background: Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one's preexisting beliefs. It is omnipresent in psychology, economics, and even scientific practices. Prior theoretical research of this phenomenon has mainly focused on its economic implications possibly missing its potential connections with broader notions of cognitive science. Methodology/Principal Findings: We formulate a (non-Bayesian) model for revising subjective probabilistic opinion of a confirmationally-biased agent in the light of a persuasive opinion. The revision rule ensures that the agent does not react to persuasion that is either far from his current opinion or coincides with it. We demonstrate that the model accounts for the basic phenomenology of the social judgment theory, and allows to study various phenomena such as cognitive dissonance and boomerang effect. The model also displays the order of presentation effect|when consecutively exposed to two opinions, the preferenc...

  6. Cosmological Evolution of Linear Bias

    CERN Document Server

    Basilakos, S; Basilakos, Spyros; Plionis, Manolis

    2000-01-01

    Using linear perturbation theory and the Friedmann-Lemaitre solutions of the cosmological field equations, we derive analytically a second-order differential equation for the evolution of the linear bias factor, b(z), between the background matter and a mass-tracer fluctuation field. We find b(z) to be a strongly dependent function of redshift in all cosmological models. Comparing our analytical solution with the semi-analytic model of Mo & White, which utilises the Press-Schechter formalism and the gravitationally induced evolution of clustering, we find an extremely good agreement even at large redshifts, once we normalize to the same bias value at two different epochs, one of which is the present. Furthermore, our analytic b(z) function agrees well with the outcome of N-body simulations even up to large redshifts.

  7. Preliminary Examination of a Cartoon-Based Hostile Attributional Bias Measure for Urban African American Boys

    Science.gov (United States)

    Leff, Stephen S.; Lefler, Elizabeth K.; Khera, Gagan S.; Paskewich, Brooke; Jawad, Abbas F.

    2014-01-01

    The current study illustrates how researchers developed and validated a cartoon-based adaptation of a written hostile attributional bias measure for a sample of urban, low-income, African American boys. A series of studies were conducted to develop cartoon illustrations to accompany a standard written hostile attributional bias vignette measure (Study 1), to determine initial psychometric properties (Study 2) and acceptability (Study 3), and to conduct a test-retest reliability trial of the adapted measure in a separate sample (Study 4). These studies utilize a participatory action research approach to measurement design and adaptation, and suggest that collaborations between researchers and key school stakeholders can lead to measures that are psychometrically strong, developmentally appropriate, and culturally sensitive. In addition, the cartoon-based hostile attributional bias measure appears to have promise as an assessment and/or outcome measure for aggression and bullying prevention programs conducted with urban African American boys. PMID:21800228

  8. Force control for robotic manipulators with structurally flexible links

    Science.gov (United States)

    Latornell, Douglas John

    1992-01-01

    This thesis reports on the development of strategies for the control of contact forces exerted by a structurally flexible robotic manipulator on surfaces in its working environment. The controller is based on a multivariable, explicitly adaptive, long range predictive control algorithm. A static equilibrium bias term which is particularly applicable to the contact force control problem has been incorporated into the control algorithm cost function. A general formulation for the discrete time domain characteristic polynomial of the closed loop system has been derived and shown useful in tuning the controller. Kinematic and dynamic models of a robotic manipulator with structurally flexible links interacting with its working environment are derived. These models include inertia and damping effects in the contact dynamics in addition to the contact stiffness employed in most previous work. Linear analyses of the dynamic models for a variety of manipulator configurations reveal that the controlled variable, the contact force, is dominated by different open loop modes of the system depending on the effective stiffness of the contacting surfaces. This result has important implications for the selection of the controller parameters. The performance of the controller has been evaluated using computer simulation. A special purpose simulation program, TWOFLEX, which includes the dynamics models of the manipulator and the environment as well as the control algorithm was developed during the research. The configurations investigated using the simulation include a single flexible manipulator link, two link manipulators with both rigid and flexible links, and a two link prototype model of the Mobile Servicing System (MSS) manipulator for the proposed Space Station Freedom. The results show that the controller can be tuned to provide fast contact force step responses with minimal overshoot and zero steady-state error. The problem of maintaining control through the discontinuous

  9. Adaptive Computing.

    Science.gov (United States)

    Harrell, William

    1999-01-01

    Provides information on various adaptive technology resources available to people with disabilities. (Contains 19 references, an annotated list of 129 websites, and 12 additional print resources.) (JOW)

  10. ADAPT Dataset

    Data.gov (United States)

    National Aeronautics and Space Administration — Advanced Diagnostics and Prognostics Testbed (ADAPT) Project Lead: Scott Poll Subject Fault diagnosis in electrical power systems Description The Advanced...

  11. BEHAVIORAL BIASES IN TRADING SECURITIES

    Directory of Open Access Journals (Sweden)

    Turcan Ciprian Sebastian

    2010-12-01

    Full Text Available The main thesis of this paper represents the importance and the effects that human behavior has over capital markets. It is important to see the link between the asset valuation and investor sentiment that motivate to pay for an asset a certain prices over/below the intrinsic value. The main behavioral aspects discussed are emotional factors such as: fear of regret, overconfidence, perseverance, loss aversion ,heuristic biases, misinformation and thinking errors, herding and their consequences.

  12. Opinion Dynamics with Confirmation Bias

    OpenAIRE

    Allahverdyan, Armen E.; Aram Galstyan

    2014-01-01

    Background: Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one's preexisting beliefs. It is omnipresent in psychology, economics, and even scientific practices. Prior theoretical research of this phenomenon has mainly focused on its economic implications possibly missing its potential connections with broader notions of cognitive science. Methodology/Principal Findings: We formulate a (non-Bayesian) model for revising subjective proba...

  13. Significant biases affecting abundance determinations

    Science.gov (United States)

    Wesson, Roger

    2015-08-01

    I have developed two highly efficient codes to automate analyses of emission line nebulae. The tools place particular emphasis on the propagation of uncertainties. The first tool, ALFA, uses a genetic algorithm to rapidly optimise the parameters of gaussian fits to line profiles. It can fit emission line spectra of arbitrary resolution, wavelength range and depth, with no user input at all. It is well suited to highly multiplexed spectroscopy such as that now being carried out with instruments such as MUSE at the VLT. The second tool, NEAT, carries out a full analysis of emission line fluxes, robustly propagating uncertainties using a Monte Carlo technique.Using these tools, I have found that considerable biases can be introduced into abundance determinations if the uncertainty distribution of emission lines is not well characterised. For weak lines, normally distributed uncertainties are generally assumed, though it is incorrect to do so, and significant biases can result. I discuss observational evidence of these biases. The two new codes contain routines to correctly characterise the probability distributions, giving more reliable results in analyses of emission line nebulae.

  14. Drag and propulsive forces in electric sails with negative polarity

    Science.gov (United States)

    Sanchez-Torres, Antonio

    2016-02-01

    An electric solar sail (E-sail) is a recent propellantless propulsion concept for a direct exploration of the Solar System. An E-sail consists of a set of bare, conductive tethers at high positive/negative bias, prone to extract solar wind momentum by Coulomb deflection of protons. Additionally, a negatively biased E-sail has been proposed as a concept for de-orbiting space debris with drag forces produced in Low Earth Orbit (LEO). The present work focuses on the negative-bias case with a sheath that must be correctly modeled for a flowing plasma ambient. Ion scattering within the sheath and the resulting force are determined for several plasma conditions. Since the plasma flow does reduce the effective range for the ion scattering within the sheath, the resulting force is then reduced. Tethers at very high negative bias should be required for extremely high plasma flow.

  15. A Spanish continuous voluntary web survey: sample bias, weighting and efficiency

    OpenAIRE

    Pedraza,, I.; Tijdens, K.; Muñoz de Bustillo, R.; Steinmetz, S

    2010-01-01

    Using micro data from a continuous volunteer web survey (CVWS), the WageIndicator (WI), this paper firstly analyses the type of bias that such a survey method produces. Secondly, following a «modelbased » approach, two alternative data weighting methodologies are implemented. Thirdly, in order to test whether weighting corrects the bias, thus making it possible to obtain conclusions applicable to the whole labour force, the efficiency of the weighting methodologies is evaluated. Since the Wag...

  16. Bias-dependent molecular-level structure of electrical double layer in ionic liquid on graphite.

    Science.gov (United States)

    Black, Jennifer M; Walters, Deron; Labuda, Aleksander; Feng, Guang; Hillesheim, Patrick C; Dai, Sheng; Cummings, Peter T; Kalinin, Sergei V; Proksch, Roger; Balke, Nina

    2013-01-01

    Here we report the bias-evolution of the electrical double layer structure of an ionic liquid on highly ordered pyrolytic graphite measured by atomic force microscopy. We observe reconfiguration under applied bias and the orientational transitions in the Stern layer. The synergy between molecular dynamics simulation and experiment provides a comprehensive picture of structural phenomena and long and short-range interactions, which improves our understanding of the mechanism of charge storage on a molecular level.

  17. The Probability Distribution for a Biased Spinner

    Science.gov (United States)

    Foster, Colin

    2012-01-01

    This article advocates biased spinners as an engaging context for statistics students. Calculating the probability of a biased spinner landing on a particular side makes valuable connections between probability and other areas of mathematics. (Contains 2 figures and 1 table.)

  18. A Pharmacological Primer of Biased Agonism

    OpenAIRE

    Andresen1, Bradley T.

    2011-01-01

    Biased agonism is one of the fastest growing topics in G protein-coupled receptor pharmacology; moreover, biased agonists are used in the clinic today: carvedilol (Coreg®) is a biased agonist of beta-adrenergic receptors. However, there is a general lack of understanding of biased agonism when compared to traditional pharmacological terminology. Therefore, this review is designed to provide a basic introduction to classical pharmacology as well as G protein-coupled receptor signal transductio...

  19. Galaxy peculiar velocities and evolution-bias

    OpenAIRE

    Percival, Will; Schafer, B.

    2007-01-01

    Galaxy bias can be split into two components: a formation-bias based on the locations of galaxy creation, and an evolution-bias that details their subsequent evolution. In this letter we consider evolution-bias in the peaks model. In this model, galaxy formation takes place at local maxima in the density field, and we analyse the subsequent peculiar motion of these galaxies in a linear model of structure formation. The peak restriction yields differences in the velocity distribution and corre...

  20. Selection bias in rheumatic disease research

    OpenAIRE

    Choi, Hyon K.; Nguyen, Uyen-Sa; Niu, Jingbo; Danaei, Goodarz; Zhang, Yuqing

    2014-01-01

    The identification of modifiable risk factors for the development of rheumatic conditions and their sequelae is crucial for reducing the substantial worldwide burden of these diseases. However, the validity of such research can be threatened by sources of bias, including confounding, measurement and selection biases. In this Review, we discuss potentially major issues of selection bias—a type of bias frequently overshadowed by other bias and feasibility issues, despite being equally or more p...

  1. Genomics of local adaptation with gene flow.

    Science.gov (United States)

    Tigano, Anna; Friesen, Vicki L

    2016-05-01

    Gene flow is a fundamental evolutionary force in adaptation that is especially important to understand as humans are rapidly changing both the natural environment and natural levels of gene flow. Theory proposes a multifaceted role for gene flow in adaptation, but it focuses mainly on the disruptive effect that gene flow has on adaptation when selection is not strong enough to prevent the loss of locally adapted alleles. The role of gene flow in adaptation is now better understood due to the recent development of both genomic models of adaptive evolution and genomic techniques, which both point to the importance of genetic architecture in the origin and maintenance of adaptation with gene flow. In this review, we discuss three main topics on the genomics of adaptation with gene flow. First, we investigate selection on migration and gene flow. Second, we discuss the three potential sources of adaptive variation in relation to the role of gene flow in the origin of adaptation. Third, we explain how local adaptation is maintained despite gene flow: we provide a synthesis of recent genomic models of adaptation, discuss the genomic mechanisms and review empirical studies on the genomics of adaptation with gene flow. Despite predictions on the disruptive effect of gene flow in adaptation, an increasing number of studies show that gene flow can promote adaptation, that local adaptations can be maintained despite high gene flow, and that genetic architecture plays a fundamental role in the origin and maintenance of local adaptation with gene flow.

  2. Modelling cognitive affective biases in major depressive disorder using rodents.

    Science.gov (United States)

    Hales, Claire A; Stuart, Sarah A; Anderson, Michael H; Robinson, Emma S J

    2014-10-01

    Major depressive disorder (MDD) affects more than 10% of the population, although our understanding of the underlying aetiology of the disease and how antidepressant drugs act to remediate symptoms is limited. Major obstacles include the lack of availability of good animal models that replicate aspects of the phenotype and tests to assay depression-like behaviour in non-human species. To date, research in rodents has been dominated by two types of assays designed to test for depression-like behaviour: behavioural despair tests, such as the forced swim test, and measures of anhedonia, such as the sucrose preference test. These tests have shown relatively good predictive validity in terms of antidepressant efficacy, but have limited translational validity. Recent developments in clinical research have revealed that cognitive affective biases (CABs) are a key feature of MDD. Through the development of neuropsychological tests to provide objective measures of CAB in humans, we have the opportunity to use 'reverse translation' to develop and evaluate whether similar methods are suitable for research into MDD using animals. The first example of this approach was reported in 2004 where rodents in a putative negative affective state were shown to exhibit pessimistic choices in a judgement bias task. Subsequent work in both judgement bias tests and a novel affective bias task suggest that these types of assay may provide translational methods for studying MDD using animals. This review considers recent work in this area and the pharmacological and translational validity of these new animal models of CABs. PMID:24467454

  3. Culturally Biased Assumptions in Counseling Psychology

    Science.gov (United States)

    Pedersen, Paul B.

    2003-01-01

    Eight clusters of culturally biased assumptions are identified for further discussion from Leong and Ponterotto's (2003) article. The presence of cultural bias demonstrates that cultural bias is so robust and pervasive that is permeates the profession of counseling psychology, even including those articles that effectively attack cultural bias…

  4. Biased managers, organizational design, and incentive provision

    OpenAIRE

    Moreira, Humberto Ataíde; Costa, Cristiano Machado; Ferreira, Daniel Bernardo Soares

    2004-01-01

    We model the tradeoff between the balance and the strength of incentives implicit in the choice between hierarchical and matrix organizational structures. We show that managerial biases determine which structure is optimal: hierarchical forms are preferred when biases are low, while matrix structures are preferred when biases are high.

  5. Spallation neutron source RF cavity bias system

    International Nuclear Information System (INIS)

    The Spallation Neutron Source r.f. cavity bias system is described under the topic headings: bias system, r.f. cavity, cables, d.c. bias power supply, transistor regulator and control system. Calculation of 4 core 300 mm solid aluminium cable inductance, coaxial shunt frequency response and transistor regulator computed frequency response, are discussed in appendices 1-3. (U.K.)

  6. Begging the Question: Is Critical Thinking Biased?

    Science.gov (United States)

    Alston, Kal

    1995-01-01

    Discusses whether critical thinking is biased, examining what is meant by critical thinking and bias and what the consequences are for addressing bias in different ways. The paper responds to the three previous papers in the critical thinking symposium in this issue of the journal. (SM)

  7. Attentional bias predicts heroin relapse following treatment

    NARCIS (Netherlands)

    M.A.E. Marissen; I.H.A. Franken; A.J. Waters; P. Blanken; W. van den Brink; V.M. Hendriks

    2006-01-01

    Aims Previous studies have shown that abstinent heroin addicts exhibit an attentional bias to heroin-related stimuli. It has been suggested that attentional bias may represent a vulnerability to relapse into drug use. In the present study, the predictive value of pre-treatment attentional bias on re

  8. Automatización de la elaboración de nutrición parenteral: adecuación a la legislación actual Automation of parenteral nutrition laboration: adaptation to in force legislation

    Directory of Open Access Journals (Sweden)

    J. M. Llop Talaverón

    2006-04-01

    fue de 2,41%, 1,35% y 1,25% respectivamente (tabla I. Esta disminución fue significativa (p=0,014. Al analizar el porcentaje de preparaciones fuera del límite de variación del 3% se observó una reducción significativa (p=0,00001 al comparar los 3 periodos (tabla II. El tiempo medio de elaboración con el SACV aumentó aproximadamente 4 minutos por bolsa (3min58s en el primer periodo estudiado y 3min10s al comparar las NP elaboradas con el SACV durante el segundo periodo de estudio con el SG. Conclusiones: El nuevo sistema de llenado de bolsas mediante control volumétrico supone un aumento en el control de la exactitud y una disminución del riesgo de superar los límites considerados aceptables. La puesta en marcha de un proceso tecnológico es una tarea difícil que implica el cambio en muchos aspectos de la actividad diaria y que hace necesario un cambio "cultural" en la Unidad de NP con el fin de optimizar todo el proceso. Sin embargo, estos aspectos permiten una adecuación a los requisitos legales existentes en cuanto a normas de correcta elaboración y control de calidad de fórmulas magistrales así como una mejora en la calidad asistencial integral.Introduction: Quality and efficiency criteria of allowances associated to technological procedures are developing in a setting that values quality, and from there the Real Decree RD175/2001 has been issued by which the rules of correct elaboration and quality control of formulations and pharmacy preparations. Parenteral nutrition (PN is a formulation and, as such, its elaboration and control have to agree with the in force regulations.With this aim, at the Bellvitge University Hospital we have developed a project for automation of elaboration of PN mixtures with the MicroMacro Pump 23 Baxa Compounder®. Objectives: To assess the impact of implementing an automated system of volumetric control in PN elaboration. Material and methods: The project development may be divided into two differentiated aspects. The

  9. A Review of Studies on Media Bias at Home

    Institute of Scientific and Technical Information of China (English)

    辛一丹

    2015-01-01

    Bias is widely existed nowadays.Domestic scholars have done a lot of research on the bias,especially the media bias.They studied the media bias from different perspectives,such as the bias on China image,the bias of a certain media FOX,the bias on the venerable group,the bias on women and so on.The author plans to give a review of the studies on media bias at home in this paper.

  10. A Review of Studies on Media Bias at Home

    Institute of Scientific and Technical Information of China (English)

    辛一丹

    2015-01-01

    Bias is widely existed nowadays. Domestic scholars have done a lot of research on the bias, especially the media bias. They studied the media bias from different perspectives, such as the bias on China image,the bias of a certain media FOX, the bias on the venerable group, the bias on women and so on. The author plans to give a review of the studies on media bias at home in this paper.

  11. Negatively-biased credulity and the cultural evolution of beliefs.

    Science.gov (United States)

    Fessler, Daniel M T; Pisor, Anne C; Navarrete, Carlos David

    2014-01-01

    The functions of cultural beliefs are often opaque to those who hold them. Accordingly, to benefit from cultural evolution's ability to solve complex adaptive problems, learners must be credulous. However, credulity entails costs, including susceptibility to exploitation, and effort wasted due to false beliefs. One determinant of the optimal level of credulity is the ratio between the costs of two types of errors: erroneous incredulity (failing to believe information that is true) and erroneous credulity (believing information that is false). This ratio can be expected to be asymmetric when information concerns hazards, as the costs of erroneous incredulity will, on average, exceed the costs of erroneous credulity; no equivalent asymmetry characterizes information concerning benefits. Natural selection can therefore be expected to have crafted learners' minds so as to be more credulous toward information concerning hazards. This negatively-biased credulity extends general negativity bias, the adaptive tendency for negative events to be more salient than positive events. Together, these biases constitute attractors that should shape cultural evolution via the aggregated effects of learners' differential retention and transmission of information. In two studies in the U.S., we demonstrate the existence of negatively-biased credulity, and show that it is most pronounced in those who believe the world to be dangerous, individuals who may constitute important nodes in cultural transmission networks. We then document the predicted imbalance in cultural content using a sample of urban legends collected from the Internet and a sample of supernatural beliefs obtained from ethnographies of a representative collection of the world's cultures, showing that beliefs about hazards predominate in both. PMID:24736596

  12. Negatively-biased credulity and the cultural evolution of beliefs.

    Directory of Open Access Journals (Sweden)

    Daniel M T Fessler

    Full Text Available The functions of cultural beliefs are often opaque to those who hold them. Accordingly, to benefit from cultural evolution's ability to solve complex adaptive problems, learners must be credulous. However, credulity entails costs, including susceptibility to exploitation, and effort wasted due to false beliefs. One determinant of the optimal level of credulity is the ratio between the costs of two types of errors: erroneous incredulity (failing to believe information that is true and erroneous credulity (believing information that is false. This ratio can be expected to be asymmetric when information concerns hazards, as the costs of erroneous incredulity will, on average, exceed the costs of erroneous credulity; no equivalent asymmetry characterizes information concerning benefits. Natural selection can therefore be expected to have crafted learners' minds so as to be more credulous toward information concerning hazards. This negatively-biased credulity extends general negativity bias, the adaptive tendency for negative events to be more salient than positive events. Together, these biases constitute attractors that should shape cultural evolution via the aggregated effects of learners' differential retention and transmission of information. In two studies in the U.S., we demonstrate the existence of negatively-biased credulity, and show that it is most pronounced in those who believe the world to be dangerous, individuals who may constitute important nodes in cultural transmission networks. We then document the predicted imbalance in cultural content using a sample of urban legends collected from the Internet and a sample of supernatural beliefs obtained from ethnographies of a representative collection of the world's cultures, showing that beliefs about hazards predominate in both.

  13. Negatively-biased credulity and the cultural evolution of beliefs.

    Science.gov (United States)

    Fessler, Daniel M T; Pisor, Anne C; Navarrete, Carlos David

    2014-01-01

    The functions of cultural beliefs are often opaque to those who hold them. Accordingly, to benefit from cultural evolution's ability to solve complex adaptive problems, learners must be credulous. However, credulity entails costs, including susceptibility to exploitation, and effort wasted due to false beliefs. One determinant of the optimal level of credulity is the ratio between the costs of two types of errors: erroneous incredulity (failing to believe information that is true) and erroneous credulity (believing information that is false). This ratio can be expected to be asymmetric when information concerns hazards, as the costs of erroneous incredulity will, on average, exceed the costs of erroneous credulity; no equivalent asymmetry characterizes information concerning benefits. Natural selection can therefore be expected to have crafted learners' minds so as to be more credulous toward information concerning hazards. This negatively-biased credulity extends general negativity bias, the adaptive tendency for negative events to be more salient than positive events. Together, these biases constitute attractors that should shape cultural evolution via the aggregated effects of learners' differential retention and transmission of information. In two studies in the U.S., we demonstrate the existence of negatively-biased credulity, and show that it is most pronounced in those who believe the world to be dangerous, individuals who may constitute important nodes in cultural transmission networks. We then document the predicted imbalance in cultural content using a sample of urban legends collected from the Internet and a sample of supernatural beliefs obtained from ethnographies of a representative collection of the world's cultures, showing that beliefs about hazards predominate in both.

  14. Oscillatory Adaptive Yaw-Plane Control of Biorobotic Autonomous Underwater Vehicles Using Pectoral-Like Fins

    Directory of Open Access Journals (Sweden)

    Mugdha S. Naik

    2007-01-01

    Full Text Available This article considers the control of a biorobotic autonomous underwater vehicle (BAUV in the yaw plane using biologically inspired oscillatory pectoral-like fins of marine animals. The fins are assumed to be oscillating harmonically with a combined linear (sway and angular (yaw motion producing unsteady forces, which are used for fish-like control of BAUVs. Manoeuvring of the BAUV in the yaw plane is accomplished by altering the bias (mean angle of the angular motion of the fin. For the derivation of the adaptive control system, it is assumed that the physical parameters, the hydrodynamic coefficients, and the fin force and moment are not known. A direct adaptive sampled-data control system for the trajectory control of the yaw-angle using only yaw-angle measurement is derived. The parameter adaptation law is based on the normalised gradient scheme. Simulation results for the set point control, sinusoidal trajectory tracking and turning manoeuvres are presented, which show that the control system accomplishes precise trajectory control in spite of the parameter uncertainties.

  15. Challenges in bias correcting climate change simulations

    Science.gov (United States)

    Maraun, Douglas; Shepherd, Ted; Zappa, Giuseppe; Gutierrez, Jose; Widmann, Martin; Hagemann, Stefan; Richter, Ingo; Soares, Pedro; Mearns, Linda

    2016-04-01

    Biases in climate model simulations - if these are directly used as input for impact models - will introduce further biases in subsequent impact simulations. In response to this issue, so-called bias correction methods have been developed to post-process climate model output. These methods are now widely used and a crucial component in the generation of high resolution climate change projections. Bias correction is conceptually similar to model output statistics, which has been successfully used for several decades in numerical weather prediction. Yet in climate science, some authors outrightly dismiss any form of bias correction. Starting from this seeming contradiction, we highlight differences between the two contexts and infer consequences and limitations for the applicability of bias correction to climate change projections. We first show that cross validation approaches successfully used to evaluate weather forecasts are fundamentally insufficient to evaluate climate change bias correction. We further demonstrate that different types of model mismatches with observations require different solutions, and some may not sensibly be mitigated. In particular we consider the influence of large-scale circulation biases, biases in the persistence of weather regimes, and regional biases caused by an insufficient representation of the flow-topography interaction. We conclude with a list of recommendations and suggestions for future research to reduce, to post-process, and to cope with climate model biases.

  16. Winning the genetic lottery: biasing birth sex ratio results in more grandchildren.

    Directory of Open Access Journals (Sweden)

    Collette M Thogerson

    Full Text Available Population dynamics predicts that on average parents should invest equally in male and female offspring; similarly, the physiology of mammalian sex determination is supposedly stochastic, producing equal numbers of sons and daughters. However, a high quality parent can maximize fitness by biasing their birth sex ratio (SR to the sex with the greatest potential to disproportionately outperform peers. All SR manipulation theories share a fundamental prediction: grandparents who bias birth SR should produce more grandoffspring via the favored sex. The celebrated examples of biased birth SRs in nature consistent with SR manipulation theories provide compelling circumstantial evidence. However, this prediction has never been directly tested in mammals, primarily because the complete three-generation pedigrees needed to test whether individual favored offspring produce more grandoffspring for the biasing grandparent are essentially impossible to obtain in nature. Three-generation pedigrees were constructed using 90 years of captive breeding records from 198 mammalian species. Male and female grandparents consistently biased their birth SR toward the sex that maximized second-generation success. The most strongly male-biased granddams and grandsires produced respectively 29% and 25% more grandoffspring than non-skewing conspecifics. The sons of the most male-biasing granddams were 2.7 times as fecund as those of granddams with a 50∶50 bias (similar results are seen in grandsires. Daughters of the strongest female-biasing granddams were 1.2 times as fecund as those of non-biasing females (this effect is not seen in grandsires. To our knowledge, these results are the first formal test of the hypothesis that birth SR manipulation is adaptive in mammals in terms of grandchildren produced, showing that SR manipulation can explain biased birth SR in general across mammalian species. These findings also have practical implications: parental control of birth

  17. Winning the genetic lottery: biasing birth sex ratio results in more grandchildren.

    Science.gov (United States)

    Thogerson, Collette M; Brady, Colleen M; Howard, Richard D; Mason, Georgia J; Pajor, Edmond A; Vicino, Greg A; Garner, Joseph P

    2013-01-01

    Population dynamics predicts that on average parents should invest equally in male and female offspring; similarly, the physiology of mammalian sex determination is supposedly stochastic, producing equal numbers of sons and daughters. However, a high quality parent can maximize fitness by biasing their birth sex ratio (SR) to the sex with the greatest potential to disproportionately outperform peers. All SR manipulation theories share a fundamental prediction: grandparents who bias birth SR should produce more grandoffspring via the favored sex. The celebrated examples of biased birth SRs in nature consistent with SR manipulation theories provide compelling circumstantial evidence. However, this prediction has never been directly tested in mammals, primarily because the complete three-generation pedigrees needed to test whether individual favored offspring produce more grandoffspring for the biasing grandparent are essentially impossible to obtain in nature. Three-generation pedigrees were constructed using 90 years of captive breeding records from 198 mammalian species. Male and female grandparents consistently biased their birth SR toward the sex that maximized second-generation success. The most strongly male-biased granddams and grandsires produced respectively 29% and 25% more grandoffspring than non-skewing conspecifics. The sons of the most male-biasing granddams were 2.7 times as fecund as those of granddams with a 50∶50 bias (similar results are seen in grandsires). Daughters of the strongest female-biasing granddams were 1.2 times as fecund as those of non-biasing females (this effect is not seen in grandsires). To our knowledge, these results are the first formal test of the hypothesis that birth SR manipulation is adaptive in mammals in terms of grandchildren produced, showing that SR manipulation can explain biased birth SR in general across mammalian species. These findings also have practical implications: parental control of birth SR has the

  18. Neuroanatomy of intergroup bias: A white matter microstructure study of individual differences.

    Science.gov (United States)

    Baumgartner, Thomas; Nash, Kyle; Hill, Christopher; Knoch, Daria

    2015-11-15

    Intergroup bias-the tendency to behave more positively toward an ingroup member than an outgroup member-is a powerful social force, for good and ill. Although it is widely demonstrated, intergroup bias is not universal, as it is characterized by significant individual differences. Recently, attention has begun to turn to whether neuroanatomy might explain these individual differences in intergroup bias. However, no research to date has examined whether white matter microstructure could help determine differences in behavior toward ingroup and outgroup members. In the current research, we examine intergroup bias with the third-party punishment paradigm and white matter integrity and connectivity strength as determined by diffusion tensor imaging (DTI). We found that both increased white matter integrity at the right temporal-parietal junction (TPJ) and connectivity strength between the right TPJ and the dorsomedial prefrontal cortex (DMPFC) were associated with increased impartiality in the third-party punishment paradigm, i.e., reduced intergroup bias. Further, consistent with the role that these brain regions play in the mentalizing network, we found that these effects were mediated by mentalizing processes. Participants with greater white matter integrity at the right TPJ and connectivity strength between the right TPJ and the DMPFC employed mentalizing processes more equally for ingroup and outgroup members, and this non-biased use of mentalizing was associated with increased impartiality. The current results help shed light on the mechanisms of bias and, potentially, on interventions that promote impartiality over intergroup bias. PMID:26275384

  19. The role of experience on techno-entrepreneurs’ decision making biases

    Directory of Open Access Journals (Sweden)

    Pouria Nouri

    2012-10-01

    Full Text Available Entrepreneurs are the driving force behind the prospect and growth of the societies. Sound and wise decisions pave the way for them to carry out these highly important functions. Entrepreneurs are to discover and exploit opportunities. Therefore, they must gather sufficient and pertinent information. Entrepreneurs, like most human beings face complex and ambiguous decision-making situations, not to mention their lack of time and source to gather and process the data. Under these circumstances, entrepreneurs are prone making biases decisions. There are many reasons identified for this entrepreneurial decision making biases, such as the high cost of rational decision making, limitations in information processing, differences in their styles and procedures, or information overload, environmental complexity, environmental uncertainty. These biases are neither totally harmful nor completely useful and have to be seen as natural human characteristics. What makes entrepreneurial decision-making biases important is their effects on the decisions and thus the outcome of the enterprises. Entrepreneurial decision-making biases, deliberate or unintentional can seal the fate of the enterprises, therefore studying them meticulously is crucial. Literature has shown that experience could be an effective factor in decision-making biases. In this paper, we try to find out the impact of experience in Iranian high tech entrepreneurs’ major decision-making biases by a qualitative approach. Finally, it was concluded that experience is influential in shaping overconfidence bias.

  20. Cassini Thruster Calibration Algorithm Using Reaction Wheel Biasing Data

    Science.gov (United States)

    Rizvi, Farheen

    2012-01-01

    Thrust force estimates for the reaction control thrusters on-board Cassini spacecraft are presented in this paper. Cassini consists of two thruster branches (A and B) each with eight thrusters. The four Z-thrusters control the X and Y-axes, while the four Y-thrusters control the Z-axis. It is important to track the thrust force estimates in order to detect any thruster degradation and for supporting various activities in spacecraft operations (Titan flyby, spacecraft maneuvers). The Euler equation, which describes the rotational motion of the spacecraft during a reaction wheel bias event, is used to develop the algorithm. The thrust estimates are obtained from the pseudo inverse solution using flight telemetry during the bias. Results show that the A-branch Z3A and Z4A thrusters exhibited degraded thrust in November 2008. Due to the degraded thrust performance of Z3A and Z4A, A-branch usage was discontinued and prime branch was swapped to B-branch in March 2009. The thrust estimates from the B-branch do not show any degradation to date. The algorithm is used to trend the B-branch thrust force estimates as the mission continues.

  1. Visual adaptation to thin and fat bodies transfers across identity.

    Directory of Open Access Journals (Sweden)

    Dennis Hummel

    Full Text Available Visual perception is highly variable and can be influenced by the surrounding world. Previous research has revealed that body perception can be biased due to adaptation to thin or fat body shapes. The aim of the present study was to show that adaptation to certain body shapes and the resulting perceptual biases transfer across different identities of adaptation and test stimuli. We designed two similar adaptation experiments in which healthy female participants adapted to pictures of either thin or fat bodies and subsequently compared more or less distorted pictures of their own body to their actual body shape. In the first experiment (n = 16 the same identity was used as adaptation and test stimuli (i.e. pictures of the participant's own body while in the second experiment (n = 16 we used pictures of unfamiliar thin or fat bodies as adaptation stimuli. We found comparable adaptation effects in both experiments: After adaptation to a thin body, participants rated a thinner than actual body picture to be the most realistic and vice versa. We therefore assume that adaptation to certain body shapes transfers across different identities. These results raise the questions of whether some type of natural adaptation occurs in everyday life. Natural and predominant exposure to certain bodily features like body shape--especially the thin ideal in Western societies--could bias perception for these features. In this regard, further research might shed light on aspects of body dissatisfaction and the development of body image disturbances in terms of eating disorders.

  2. Eligibility of disabled veterans and members of the armed forces with severe burn injuries for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment. Final rule.

    Science.gov (United States)

    2013-09-19

    The Department of Veterans Affairs (VA) adopts as a final rule its proposal to amend its adjudication regulation concerning a certificate of eligibility for financial assistance in the purchase of an automobile or other conveyance and adaptive equipment, which was published in the Federal Register on November 5, 2012, and republished for minor technical corrections on November 26, 2012. The amendment is necessary to incorporate statutory changes made by the Veterans' Benefits Act of 2010.

  3. Neural adaptations to electrical stimulation strength training

    NARCIS (Netherlands)

    Hortobagyi, Tibor; Maffiuletti, Nicola A.

    2011-01-01

    This review provides evidence for the hypothesis that electrostimulation strength training (EST) increases the force of a maximal voluntary contraction (MVC) through neural adaptations in healthy skeletal muscle. Although electrical stimulation and voluntary effort activate muscle differently, there

  4. Importance biasing scheme implemented in the PRIZMA code

    Energy Technology Data Exchange (ETDEWEB)

    Kandiev, I.Z.; Malyshkin, G.N. [Russian Federal Nuclear Center-All-Russia Scientific-Technical Inst. of Technical Physics, Snezhinsk (Russian Federation)

    1997-12-31

    PRIZMA code is intended for Monte Carlo calculations of linear radiation transport problems. The code has wide capabilities to describe geometry, sources, material composition, and to obtain parameters specified by user. There is a capability to calculate path of particle cascade (including neutrons, photons, electrons, positrons and heavy charged particles) taking into account possible transmutations. Importance biasing scheme was implemented to solve the problems which require calculation of functionals related to small probabilities (for example, problems of protection against radiation, problems of detection, etc.). The scheme enables to adapt trajectory building algorithm to problem peculiarities.

  5. EPA Water Resources Adaptation Program (WRAP) Research and Development Activities Methods and Techniques

    Science.gov (United States)

    Adaptation to environmental change is not a new concept. Humans have shown throughout history a capacity for adapting to different climates and environmental changes. Farmers, foresters, civil engineers, have all been forced to adapt to numerous challenges to overcome adversity...

  6. Emotional perceptions in mice: studies on judgement bias and behavioural habituation

    OpenAIRE

    Boleij, H.

    2013-01-01

    This thesis aimed at developing a better understanding on how mice perceive their own emotional state. Next to extending on previous research on the adaptive capacities laboratory mice, we aimed at approaching the emotional perceptions of mice by establishing a behavioural test for the assessment of judgement bias. Adaptive behaviour translates into the waning of a behavioural response over time (i.e. behavioural habituation). Evaluation of behavioural habituation therefore offers a valuable ...

  7. Is adaptation. Truly an adaptation? Is adaptation. Truly an adaptation?

    Directory of Open Access Journals (Sweden)

    Thais Flores Nogueira Diniz

    2008-04-01

    Full Text Available The article begins by historicizing film adaptation from the arrival of cinema, pointing out the many theoretical approaches under which the process has been seen: from the concept of “the same story told in a different medium” to a comprehensible definition such as “the process through which works can be transformed, forming an intersection of textual surfaces, quotations, conflations and inversions of other texts”. To illustrate this new concept, the article discusses Spike Jonze’s film Adaptation. according to James Naremore’s proposal which considers the study of adaptation as part of a general theory of repetition, joined with the study of recycling, remaking, and every form of retelling. The film deals with the attempt by the scriptwriter Charles Kaufman, cast by Nicholas Cage, to adapt/translate a non-fictional book to the cinema, but ends up with a kind of film which is by no means what it intended to be: a film of action in the model of Hollywood productions. During the process of creation, Charles and his twin brother, Donald, undergo a series of adventures involving some real persons from the world of film, the author and the protagonist of the book, all of them turning into fictional characters in the film. In the film, adaptation then signifies something different from itstraditional meaning. The article begins by historicizing film adaptation from the arrival of cinema, pointing out the many theoretical approaches under which the process has been seen: from the concept of “the same story told in a different medium” to a comprehensible definition such as “the process through which works can be transformed, forming an intersection of textual surfaces, quotations, conflations and inversions of other texts”. To illustrate this new concept, the article discusses Spike Jonze’s film Adaptation. according to James Naremore’s proposal which considers the study of adaptation as part of a general theory of repetition

  8. Selection bias in rheumatic disease research

    Science.gov (United States)

    Choi, Hyon K.; Nguyen, Uyen-Sa; Niu, Jingbo; Danaei, Goodarz; Zhang, Yuqing

    2014-01-01

    The identification of modifiable risk factors for the development of rheumatic conditions and their sequelae is crucial for reducing the substantial worldwide burden of these diseases. However, the validity of such research can be threatened by sources of bias, including confounding, measurement and selection biases. In this Review, we discuss potentially major issues of selection bias—a type of bias frequently overshadowed by other bias and feasibility issues, despite being equally or more problematic—in key areas of rheumatic disease research. We present index event bias (a type of selection bias) as one of the potentially unifying reasons behind some unexpected findings, such as the ‘risk factor paradox’—a phenomenon exemplified by the discrepant effects of certain risk factors on the development versus the progression of osteoarthritis (OA) or rheumatoid arthritis (RA). We also discuss potential selection biases owing to differential loss to follow-up in RA and OA research, as well as those due to the depletion of susceptibles (prevalent user bias) and immortal time bias. The lesson remains that selection bias can be ubiquitous and, therefore, has the potential to lead the field astray. Thus, we conclude with suggestions to help investigators avoid such issues and limit the impact on future rheumatology research. PMID:24686510

  9. Best practice in police social media adaptation

    OpenAIRE

    Denef, Sebastian; Kaptein, Nico; Bayerl, Petra Saskia; Ramirez, Leonardo

    2012-01-01

    textabstractSummary: Best Practice in Police Social Media Adaptation. This document describes best practice of European police forces in adapting social media. The description of these practices stems from a workshop series and other events where police ICT experts met with academics and industry experts; and from a study of the Twitter usage of British police forces during the 2011 riots. Grouped in nine categories, we describe different uses and implementation strategies of social media by ...

  10. Bayesian item selection in constrained adaptive testing using shadow tests

    NARCIS (Netherlands)

    Veldkamp, Bernard P.

    2010-01-01

    Application of Bayesian item selection criteria in computerized adaptive testing might result in improvement of bias and MSE of the ability estimates. The question remains how to apply Bayesian item selection criteria in the context of constrained adaptive testing, where large numbers of specificati

  11. Bayesian Item Selection in Constrained Adaptive Testing Using Shadow Tests

    Science.gov (United States)

    Veldkamp, Bernard P.

    2010-01-01

    Application of Bayesian item selection criteria in computerized adaptive testing might result in improvement of bias and MSE of the ability estimates. The question remains how to apply Bayesian item selection criteria in the context of constrained adaptive testing, where large numbers of specifications have to be taken into account in the item…

  12. Social reward shapes attentional biases.

    Science.gov (United States)

    Anderson, Brian A

    2016-01-01

    Paying attention to stimuli that predict a reward outcome is important for an organism to survive and thrive. When visual stimuli are associated with tangible, extrinsic rewards such as money or food, these stimuli acquire high attentional priority and come to automatically capture attention. In humans and other primates, however, many behaviors are not motivated directly by such extrinsic rewards, but rather by the social feedback that results from performing those behaviors. In the present study, I examine whether positive social feedback can similarly influence attentional bias. The results show that stimuli previously associated with a high probability of positive social feedback elicit value-driven attentional capture, much like stimuli associated with extrinsic rewards. Unlike with extrinsic rewards, however, such stimuli also influence task-specific motivation. My findings offer a potential mechanism by which social reward shapes the information that we prioritize when perceiving the world around us. PMID:25941868

  13. Forecasts: uncertain, inaccurate and biased?

    DEFF Research Database (Denmark)

    Nicolaisen, Morten Skou; Ambrasaite, Inga; Salling, Kim Bang

    2012-01-01

    construction costs, which account for the majority of total project costs. Second are the forecasts of travel time savings, which account for the majority of total project benefits. The latter of these is, inter alia, determined by forecasts of travel demand, which we shall use as a proxy for the forecasting......Cost Benefit Analysis (CBA) is the dominating methodology for appraisal of transport infrastructure projects across the globe. In order to adequately assess the costs and benefits of such projects two types of forecasts are crucial to the validity of the appraisal. First are the forecasts of...... accuracy of project benefits. This paper presents results from an on-going research project on uncertainties in transport project evaluation (UNITE) that find forecasts of demand to be not only uncertain, but at times also highly inaccurate and often displaying a concerning degree of bias. Demand for road...

  14. Bias in Peripheral Depression Biomarkers

    DEFF Research Database (Denmark)

    Carvalho, André F; Köhler, Cristiano A; Brunoni, André R;

    2016-01-01

    BACKGROUND: To aid in the differentiation of individuals with major depressive disorder (MDD) from healthy controls, numerous peripheral biomarkers have been proposed. To date, no comprehensive evaluation of the existence of bias favoring the publication of significant results or inflating effect...... sizes has been conducted. METHODS: Here, we performed a comprehensive review of meta-analyses of peripheral nongenetic biomarkers that could discriminate individuals with MDD from nondepressed controls. PubMed/MEDLINE, EMBASE, and PsycINFO databases were searched through April 10, 2015. RESULTS: From 15......-analyses, while 11 meta-analyses had evidence of small-study effects. CONCLUSIONS: Our findings suggest that there is an excess of studies with statistically significant results in the literature of peripheral biomarkers for MDD. The selective publication of 'positive studies' and the selective reporting...

  15. Modeling confirmation bias and polarization

    CERN Document Server

    Del Vicario, Michela; Caldarelli, Guido; Stanley, H Eugene; Quattrociocchi, Walter

    2016-01-01

    Online users tend to select claims that adhere to their system of beliefs and to ignore dissenting information. Confirmation bias, indeed, plays a pivotal role in viral phenomena. Furthermore, the wide availability of content on the web fosters the aggregation of likeminded people where debates tend to enforce group polarization. Such a configuration might alter the public debate and thus the formation of the public opinion. In this paper we provide a mathematical model to study online social debates and the related polarization dynamics. We assume the basic updating rule of the Bounded Confidence Model (BCM) and we develop two variations a) the Rewire with Bounded Confidence Model (RBCM), in which discordant links are broken until convergence is reached; and b) the Unbounded Confidence Model, under which the interaction among discordant pairs of users is allowed even with a negative feedback, either with the rewiring step (RUCM) or without it (UCM). From numerical simulations we find that the new models (UCM...

  16. The effect of force feedback delay on stiffness perception and grip force modulation during tool-mediated interaction with elastic force fields.

    Science.gov (United States)

    Leib, Raz; Karniel, Amir; Nisky, Ilana

    2015-05-01

    During interaction with objects, we form an internal representation of their mechanical properties. This representation is used for perception and for guiding actions, such as in precision grip, where grip force is modulated with the predicted load forces. In this study, we explored the relationship between grip force adjustment and perception of stiffness during interaction with linear elastic force fields. In a forced-choice paradigm, participants probed pairs of virtual force fields while grasping a force sensor that was attached to a haptic device. For each pair, they were asked which field had higher level of stiffness. In half of the pairs, the force feedback of one of the fields was delayed. Participants underestimated the stiffness of the delayed field relatively to the nondelayed, but their grip force characteristics were similar in both conditions. We analyzed the magnitude of the grip force and the lag between the grip force and the load force in the exploratory probing movements within each trial. Right before answering which force field had higher level of stiffness, both magnitude and lag were similar between delayed and nondelayed force fields. These results suggest that an accurate internal representation of environment stiffness and time delay was used for adjusting the grip force. However, this representation did not help in eliminating the bias in stiffness perception. We argue that during performance of a perceptual task that is based on proprioceptive feedback, separate neural mechanisms are responsible for perception and action-related computations in the brain.

  17. A Simulation Platform for Quantifying Survival Bias

    DEFF Research Database (Denmark)

    Mayeda, Elizabeth Rose; Tchetgen Tchetgen, Eric J; Power, Melinda C;

    2016-01-01

    with the situation with no collider bias, the magnitude of bias was higher when exposure and an unmeasured determinant of cognitive decline interacted on the hazard ratio scale to influence mortality or when both exposure and rate of cognitive decline influenced mortality. Bias was, as expected, larger in high......-mortality situations. This simulation platform provides a flexible tool for evaluating biases in studies with high mortality, as is common in cognitive aging research.......Bias due to selective mortality is a potential concern in many studies and is especially relevant in cognitive aging research because cognitive impairment strongly predicts subsequent mortality. Biased estimation of the effect of an exposure on rate of cognitive decline can occur when mortality...

  18. Professional Culture and Climate: Addressing Unconscious Bias

    Science.gov (United States)

    Knezek, Patricia

    2016-10-01

    Unconscious bias reflects expectations or stereotypes that influence our judgments of others (regardless of our own group). Everyone has unconscious biases. The end result of unconscious bias can be an accumulation of advantage or disadvantage that impacts the long term career success of individuals, depending on which biases they are subject to. In order to foster a professional culture and climate, being aware of these unconscious biases and mitigating against them is a first step. This is particularly important when judgements are needed, such as in cases for recruitment, choice of speakers for conferences, and even reviewing papers submitted for publication. This presentation will cover how unconscious bias manifests itself, what evidence exists to demonstrate it exists, and ways it can be addressed.

  19. Biased random walks on multiplex networks

    CERN Document Server

    Battiston, Federico; Latora, Vito

    2015-01-01

    Biased random walks on complex networks are a particular type of walks whose motion is biased on properties of the destination node, such as its degree. In recent years they have been exploited to design efficient strategies to explore a network, for instance by constructing maximally mixing trajectories or by sampling homogeneously the nodes. In multiplex networks, the nodes are related through different types of links (layers or communication channels), and the presence of connections at different layers multiplies the number of possible paths in the graph. In this work we introduce biased random walks on multiplex networks and provide analytical solutions for their long-term properties such as the stationary distribution and the entropy rate. We focus on degree-biased walks and distinguish between two subclasses of random walks: extensive biased walks consider the properties of each node separately at each layer, intensive biased walks deal instead with intrinsically multiplex variables. We study the effec...

  20. Investigation of the depletion layer by scanning capacitance force microscopy with Kelvin probe force microscopy

    Science.gov (United States)

    Uruma, Takeshi; Satoh, Nobuo; Yamamoto, Hidekazu

    2016-08-01

    We have developed a scanning probe microscope (SPM) that combines atomic force microscopy (AFM) with both Kelvin probe force microscopy (KFM — to measure the surface potential) and scanning capacitance force microscopy (SCFM — to measure the differential capacitance). The surface physical characteristics of a commercial Si Schottky barrier diode (Si-SBD), with and without an applied reverse bias, were measured over the same area by our AFM/KFM/SCFM system. We thus investigated the discrete power device by calculating the depletion-layer width and drawing an energy-band diagram.

  1. Childhood Obesity: Issues of Weight Bias

    OpenAIRE

    Washington, Reginald L.

    2011-01-01

    Although the effects of obesity on children's physical health are well documented, the social consequences of obesity are less well described and may not be addressed in intervention programs. Weight bias may take several forms. It may result in teasing and discrimination and may affect employment and educational opportunities. Health care providers may limit care of overweight or obese children. The media promote weight bias in multiple ways. Some parents are biased against their obese child...

  2. BUSINESS LEADERSHIP BIASES: ANDROCENTRISM, ETHNOCENTRISM AND CHRONOCENTRISM

    OpenAIRE

    SOFICA Aurelian; NEGRUTA Adina

    2012-01-01

    The aim of the paper is to explore the unconscious biases that accompany the business leadership icons. The main objectives of the paper are: to look for evidence of leadership biases on ground of gender (androcentrism), ethnicity (ethnocentrism) and age (cronocentrism); to look for potential reasons behind the biases and for potential effects at the organizational and social level. The article confirms some of the evidence from various international empirical or theoretical studies, and prop...

  3. Exponential Growth Bias and Financial Literacy

    OpenAIRE

    Almenberg, Johan; Gerdes, Christer

    2011-01-01

    The tendency to underestimate the future value of a variable growing at a constant rate, an example of exponential growth bias, has been linked to household financial decision making. We show that exponential growth bias and standard measures of financial literacy are negatively correlated in a representative sample of Swedish adults. Since financial literacy is linked to household decision making, our results indicate that examining the relationship between exponential growth bias and househ...

  4. Voter Confirmation Bias and Electoral Accountability

    OpenAIRE

    Lockwood, Benjamin

    2015-01-01

    This paper considers the implications of an important cognitive bias in information processing, confirmation bias, in a political agency setting. In the baseline two-period case where only the politician’s actions are observable before the election, we show that when voters have this bias, it decreases pandering by the incumbent, and can raise voter welfare as a consequence. This result is robust in several directions, including to the case where the voter can also observe payoffs with some p...

  5. Analysis of burnup credit on spent fuel transport / storage casks - estimation of reactivity bias

    International Nuclear Information System (INIS)

    Chemical analyses of high burnup UO2 (65 GWd/t) and MOX (45 GWd/t) spent fuel pins were carried out. Measured data of nuclides' composition from U234 to P 242 were used for evaluation of ORIGEN-2/82 code and a nuclear fuel design code (NULIF). Critically calculations were executed for transport and storage casks for 52 BWR or 21 PWR spent fuel assemblies. The reactivity biases were evaluated for axial and horizontal profiles of burnup, and historical void fraction (BWR), operational histories such as control rod insertion history, BPR insertion history and others, and calculational accuracy of ORIGEN-2/82 on nuclides' composition. This study shows that introduction of burnup credit has a large merit in criticality safety analysis of casks, even if these reactivity biases are considered. The concept of equivalent uniform burnup was adapted for the present reactivity bias evaluation and showed the possibility of simplifying the reactivity bias evaluation in burnup credit. (authors)

  6. Best practice in police social media adaptation

    NARCIS (Netherlands)

    S. Denef (Sebastian); N. Kaptein (Nico); P.S. Bayerl (Petra Saskia); L. Ramirez (Leonardo)

    2012-01-01

    textabstractSummary: Best Practice in Police Social Media Adaptation. This document describes best practice of European police forces in adapting social media. The description of these practices stems from a workshop series and other events where police ICT experts met with academics and industry ex

  7. Weak coin flipping with small bias

    CERN Document Server

    Kerenidis, I; Kerenidis, Iordanis; Nayak, Ashwin

    2002-01-01

    This note presents a quantum protocol that demonstrates that_weak_ coin flipping with bias approximately 0.239, less than 1/4, is possible. A bias of 1/4 was the smallest known, and followed from the strong coin flipping protocol of [Ambainis 2001]. Protocols with yet smaller bias, approximately 0.207, have independently been discovered [Ambainis 2001, Spekkens and Rudolph 2002]. We also present an alternative strong coin flipping protocol with bias 1/4 with analysis simpler than that of [Ambainis 2001].

  8. Detecting Gender Bias Through Test Item Analysis

    Science.gov (United States)

    González-Espada, Wilson J.

    2009-03-01

    Many physical science and physics instructors might not be trained in pedagogically appropriate test construction methods. This could lead to test items that do not measure what they are intended to measure. A subgroup of these items might show bias against some groups of students. This paper describes how the author became aware of potentially biased items against females in his examinations, which led to the exploration of fundamental issues related to item validity, gender bias, and differential item functioning, or DIF. A brief discussion of DIF in the context of university courses, as well as practical suggestions to detect possible gender-biased items, follows.

  9. Adaptive test

    DEFF Research Database (Denmark)

    Kjeldsen, Lars Peter; Eriksen, Mette Rose

    2010-01-01

    Artikelen er en evaluering af de adaptive tests, som blev indført i folkeskolen. Artiklen sætter særligt fokus på evaluering i folkeskolen, herunder bidrager den med vejledning til evaluering, evalueringsværktøjer og fagspecifkt evalueringsmateriale.......Artikelen er en evaluering af de adaptive tests, som blev indført i folkeskolen. Artiklen sætter særligt fokus på evaluering i folkeskolen, herunder bidrager den med vejledning til evaluering, evalueringsværktøjer og fagspecifkt evalueringsmateriale....

  10. Strategic Adaptation

    DEFF Research Database (Denmark)

    Andersen, Torben Juul

    2015-01-01

    This article provides an overview of theoretical contributions that have influenced the discourse around strategic adaptation including contingency perspectives, strategic fit reasoning, decision structure, information processing, corporate entrepreneurship, and strategy process. The related...... concepts of strategic renewal, dynamic managerial capabilities, dynamic capabilities, and strategic response capabilities are discussed and contextualized against strategic responsiveness. The insights derived from this article are used to outline the contours of a dynamic process of strategic adaptation....... This model incorporates elements of central strategizing, autonomous entrepreneurial behavior, interactive information processing, and open communication systems that enhance the organization's ability to observe exogenous changes and respond effectively to them....

  11. Adaptive management

    Science.gov (United States)

    Allen, Craig R.; Garmestani, Ahjond S.

    2015-01-01

    Adaptive management is an approach to natural resource management that emphasizes learning through management where knowledge is incomplete, and when, despite inherent uncertainty, managers and policymakers must act. Unlike a traditional trial and error approach, adaptive management has explicit structure, including a careful elucidation of goals, identification of alternative management objectives and hypotheses of causation, and procedures for the collection of data followed by evaluation and reiteration. The process is iterative, and serves to reduce uncertainty, build knowledge and improve management over time in a goal-oriented and structured process.

  12. Biasing the random walk of a molecular motor

    Energy Technology Data Exchange (ETDEWEB)

    Astumian, R Dean [Department of Physics, University of Maine, Orono, ME 04469-5709 (United States)

    2005-11-30

    Biomolecular motors are often described in mechanical terms, with analogy to cars, turbines, judo throws, levers, etc. It is important to remember however that because of their small size, and because of the aqueous environment in which molecular motors move, viscous drag and thermal noise dominate the inertial forces that drive macroscopic machines. The sequence of motions-conformational changes-by which a motor protein moves can best be described as a random walk, with transitions from one state to another occurring by thermal activation over energy barriers. In this paper I will address the question of how this random walk is biased by a non-equilibrium chemical reaction (ATP hydrolysis) so that the motor molecule moves preferentially (with almost unit certainty) in one direction, even when an external force is applied to drive it in the opposite direction. I will also discuss how these 'soft matter' motors can achieve thermodynamic efficiencies of nearly 100%.

  13. Applying a Force and Motion Learning Progression over an Extended Time Span Using the Force Concept Inventory

    Science.gov (United States)

    Fulmer, Gavin W.; Liang, Ling L.; Liu, Xiufeng

    2014-01-01

    This exploratory study applied a proposed force and motion learning progression (LP) to high-school and university students and to content involving both one- and two-dimensional force and motion situations. The Force Concept Inventory (FCI) was adapted, based on a previous content analysis and coding of the questions in the FCI in terms of the…

  14. Adaptive Robust Variable Selection

    CERN Document Server

    Fan, Jianqing; Barut, Emre

    2012-01-01

    Heavy-tailed high-dimensional data are commonly encountered in various scientific fields and pose great challenges to modern statistical analysis. A natural procedure to address this problem is to use penalized least absolute deviation (LAD) method with weighted $L_1$-penalty, called weighted robust Lasso (WR-Lasso), in which weights are introduced to ameliorate the bias problem induced by the $L_1$-penalty. In the ultra-high dimensional setting, where the dimensionality can grow exponentially with the sample size, we investigate the model selection oracle property and establish the asymptotic normality of the WR-Lasso. We show that only mild conditions on the model error distribution are needed. Our theoretical results also reveal that adaptive choice of the weight vector is essential for the WR-Lasso to enjoy these nice asymptotic properties. To make the WR-Lasso practically feasible, we propose a two-step procedure, called adaptive robust Lasso (AR-Lasso), in which the weight vector in the second step is c...

  15. Mass modeling of galaxy clusters: quantifying hydrostatic bias and contribution from non-thermal pressure

    CERN Document Server

    Martizzi, Davide

    2016-01-01

    Galaxy cluster mass determinations achieved using X-ray and Sunyaev-Zeldovich data combined with the assumption of hydrostatic equilibrium are generally biased. The bias exists for two main reasons: non-thermal pressure forces are expected to contribute to the overall pressure balance and deviations from spherical symmetry and hydrostatic equilibrium can be present. In this paper, we use a sample of zoom-in hydrodynamical simulations of galaxy clusters to measure the magnitude of hydrostatic bias and the contribution from turbulence to the total pressure. We propose a new empirical model for turbulent pressure based on our simulations that can be applied to observations. We show that our model can be successfully applied to remove most of the bias related to neglection of turbulent pressure, which is usually not included in hydrostatic cluster mass profile reconstructions. The use of this model may significantly improve the calibration of cluster scaling relations that are a key tool for cluster cosmology.

  16. Complex Internal Bias Fields in Ferroelectric Hafnium Oxide.

    Science.gov (United States)

    Schenk, Tony; Hoffmann, Michael; Ocker, Johannes; Pešić, Milan; Mikolajick, Thomas; Schroeder, Uwe

    2015-09-16

    For the rather new hafnia- and zirconia-based ferroelectrics, a lot of questions are still unsettled. Among them is the electric field cycling behavior consisting of (1) wake-up, (2) fatigue, and (3) the recently discovered subcycling-induced split-up/merging effect of transient current peaks in a hysteresis measurement. In the present work, first-order reversal curves (FORCs) are applied to study the evolution of the switching and backswitching field distribution within the frame of the Preisach model for three different phenomena: (1) The pristine film contains two oppositely biased regions. These internal bias fields vanish during the wake-up cycling. (2) Fatigue as a decrease in the number of switchable domains is accompanied by a slight increase in the mean absolute value of the switching field. (3) The split-up effect is shown to also be related to local bias fields in a complex situation resulting from both the field cycling treatment and the measurement procedure. Moreover, the role of the wake-up phenomenon is discussed with respect to optimizing low-voltage operation conditions of ferroelectric memories toward reasonably high and stable remanent polarization and highest possible endurance. PMID:26308500

  17. Going round the bend: Persistent personal biases in walked angles.

    Science.gov (United States)

    Jetzschke, Simon; Ernst, Marc O; Moscatelli, Alessandro; Boeddeker, Norbert

    2016-03-23

    For navigation through our environment, we can rely on information from various modalities, such as vision and audition. This information enables us for example to estimate our position relative to the starting position, or to integrate velocity and acceleration signals from the vestibular organ and proprioception to estimate the displacement due to self-motion. To better understand the mechanisms that underlie human navigation we analysed the performance of participants in an angle-walking task in the absence of visual and auditory signals. To this end, we guided them along paths of different lengths and asked them to turn by an angle of ±90°. We found significant biases in turn angles, i.e. systematic deviations from the correct angle and that these were characteristic for individual participants. Varying path length, however, had little effect on turn accuracy and precision. To check whether this idiosyncrasy was persistent over time and present in another type of walking task, we performed a second experiment several weeks later. Here, the same participants were guided to walk angles with varying amplitude. We then asked them to judge whether they had walked an angle larger or smaller than 90° in a two-alternative forced-choice paradigm. The personal bias was highly correlated between the two experiments even though they were conducted weeks apart. The presence of a persistent bias in walked angles in the absence of external directional cues indicates a possible error component for navigation, which is surprisingly time stable and idiosyncratic. PMID:26854843

  18. A novel high-sensitivity electrostatic biased electric field sensor

    International Nuclear Information System (INIS)

    In this paper, an electric field sensor (EFS) with high sensitivity is proposed for low-frequency weak-strength ac electric field (E-field) measurements. The EFS is based on a piezoelectric cantilever biased by a strong electrostatic field. The electrostatic bias can enhance the electric field force of a weak ac E-field, thus the cantilever can oscillate in a weak ac E-field and the device sensitivity improves. Theoretical analyses have been established and suggest that a stronger strength of electrostatic field bias would produce a higher sensitivity improvement. In the experiment, a demonstrated sensor consisting of a polyvinylidene fluoride (PVDF) piezoelectric cantilever and a polytetrafluoroethylene (PTFE) electret was built and tested. Instead of extra voltage sources, the PTFE electret was charged to provide the electrostatic field, allowing the EFS a low energy consumption and a simple electric circuit design. The experiment results show good agreement with the simulation. The sensitivity of the cantilever E-field sensor reached 0.84 mV (kV/m)−1 when the surface potential of the electret was  −770 V. (paper)

  19. Experimental analysis of biasing elements for dielectric electro-active polymers

    Science.gov (United States)

    Hodgins, Micah; Seelecke, Stefan

    2011-04-01

    This paper presents an experimental investigation of three different, small profile and scalable DEAP actuators. These actuators are designed for use in small scale pumping and valve applications. The actuators used in this paper consist of a biasing element (either a mass, linear spring, or a non-linear spring) coupled with a circular dielectric electro-active polymer (DEAP). These mechanisms bias the DEAP allowing out-of-plane actuation when the voltage is cycled. A constant force input, a linear spring, and a non-linear spring are separately tested as the biasing element of a circular/diaphragm DEAP. Tests are systematically performed at various DEAP pre-deflections, biasing stiffness and electrical loading rates. The displacement stroke performance of each test is examined and analyzed. It was found that the non-linear spring provided the largest displacement stroke over two other biasing elements. It also showed better performance at higher electrical loading rates. Thus, of the three types of biasing tested the non-linear spring shows most promise for use in fluid pump/valve applications. Future work will include optimizing this biasing element for the current DEAP design.

  20. Measurement bias and multidimensionality; an illustration of bias detection in multidimensonal measurement models

    OpenAIRE

    Jak, S.; Oort, F.J.; Dolan, C. V.

    2010-01-01

    Restricted factor analysis can be used to investigate measurement bias. A prerequisite for the detection of measurement bias through factor analysis is the correct specification of the measurement model. We applied restricted factor analysis to two subtests of a Dutch cognitive ability test. These two examples serve to illustrate the relationship between multidimensionality and measurement bias. We conclude that measurement bias implies multidimensionality, whereas multidimensionality shows u...

  1. Zero-bias spin separation

    Science.gov (United States)

    Ganichev, Sergey D.; Bel'Kov, Vasily V.; Tarasenko, Sergey A.; Danilov, Sergey N.; Giglberger, Stephan; Hoffmann, Christoph; Ivchenko, Eougenious L.; Weiss, Dieter; Wegscheider, Werner; Gerl, Christian; Schuh, Dieter; Stahl, Joachim; de Boeck, Jo; Borghs, Gustaaf; Prettl, Wilhelm

    2006-09-01

    The generation, manipulation and detection of spin-polarized electrons in low-dimensional semiconductors are at the heart of spintronics. Pure spin currents, that is, fluxes of magnetization without charge current, are quite attractive in this respect. A paradigmatic example is the spin Hall effect, where an electrical current drives a transverse spin current and causes a non-equilibrium spin accumulation observed near the sample boundary. Here we provide evidence for an another effect causing spin currents which is fundamentally different from the spin Hall effect. In contrast to the spin Hall effect, it does not require an electric current to flow: without bias the spin separation is achieved by spin-dependent scattering of electrons in media with suitable symmetry. We show, by free-carrier absorption of terahertz (THz) radiation, that spin currents flow in a wide range of temperatures. Moreover, the experimental results provide evidence that simple electron gas heating by any means is already sufficient to yield spin separation due to spin-dependent energy-relaxation processes.

  2. A simple model for biased divertors

    Energy Technology Data Exchange (ETDEWEB)

    Lachambre, J.-L.; Quirion, B.; Gunn, J.; Boucher, C.; Stansfield, B.; Gauvreau, J.-L. [Centre canadien de fusion magnetique, 1804, boulevard Lionel-Boulet, Varennes, Quebec, J3X 1S1 (Canada)

    1997-12-01

    Ionization near the target plate is shown to play an important role in biasing experiments. Our previous SOL model, which calculates the induced radial electric field, is found to be inadequate to treat the new divertor geometry of TdeV. When recycling is included via the measured D{sub {alpha}} emission near the plate, the upgraded model correctly reproduces all the observed electric currents and fields during biasing in the new divertor configuration. A simple divertor model using this calculated field has been developed to simulate the evolution of the divertor ion and neutral parameters under the action of neutralization plate biasing. Using a 1D adiabatic fluid model for the divertor ions, a 1D convective representation for the SOL neutrals and a 0D calculation for the plenum pressure, this divertor model satisfactorily simulates most of the TdeV biasing experiments at all biasing voltages and all toroidal field directions at low line-averaged densities. The weaker agreement at high densities is largely a consequence of the crudeness of the general divertor physics rather than of the deficiency of the biasing physics implemented in the model. The model is finally used to explain the polarity asymmetries observed in divertor efficiencies during biasing, and to demonstrate that no mechanism other than plate current saturation is required to interpret the saturation of toroidal rotation observed in the SOL at large biasing voltages of either polarity. (author)

  3. Production bias and cluster annihilation: Why necessary?

    DEFF Research Database (Denmark)

    Singh, B.N.; Trinkaus, H.; Woo, C.H.

    1994-01-01

    the primary cluster density is high. Therefore, a sustained high swelling rate driven by production bias must involve the annihilation of primary clusters at sinks. A number of experimental observations which are unexplainable in terms of the conventional dislocation bias for monointerstitials is...

  4. EVIDENCE OF NATIONALISTIC BIAS IN MUAYTHAI

    Directory of Open Access Journals (Sweden)

    Tony D. Myers

    2006-07-01

    Full Text Available MuayThai is a combat sport with a growing international profile but limited research conducted into judging practices and processes. Problems with judging of other subjectively judged combat sports have caused controversy at major international tournaments that have resulted in changes to scoring methods. Nationalistic bias has been central to these problems and has been identified across a range of sports. The aim of this study was to examine nationalistic bias in MuayThai. Data were collected from the International Federation of MuayThai Amateur (IFMA World Championships held in Almaty, Kazakhstan September 2003 and comprised of tournament results from 70 A-class MuayThai bouts each judged by between five and nine judges. Bouts examined featured 62 competitors from 21 countries and 25 judges from 11 countries. Results suggested that nationalistic bias was evident. The bias observed equated to approximately one round difference between opposing judges over the course of a bout (a mean of 1.09 (SE=0.50 points difference between judges with opposing affilations. The number of neutral judges used meant that this level of bias generally did not influence the outcome of bouts. Future research should explore other ingroup biases, such as nearest neighbour bias and political bias as well as investigating the feasibility adopting an electronic scoring system

  5. Racially Biased Policing: Determinants of Citizen Perceptions

    Science.gov (United States)

    Weitzer, Ronald; Tuch, Steven A.

    2005-01-01

    The current controversy surrounding racial profiling in America has focused renewed attention on the larger issue of racial bias by the police. Yet little is known about the extent of police racial bias and even less about public perceptions of the problem. This article analyzes recent national survey data on citizens' views of and reported…

  6. A specific attentional bias in suicide attempters

    NARCIS (Netherlands)

    Becker, E.S.; Strohbach, D.; Rinck, M.

    1999-01-01

    Selective attention in patients after an attempted suicide was investigated to find out whether a specific attentional bias for suicide-related materials exists and to clarify the possible role of emotions in the bias. Thirty-one patients who had previously attempted to commit suicide and 31 control

  7. delta-biased Josephson tunnel junctions

    DEFF Research Database (Denmark)

    Monaco, R.; Mygind, Jesper; Koshelet, V.;

    2010-01-01

    Abstract: The behavior of a long Josephson tunnel junction drastically depends on the distribution of the dc bias current. We investigate the case in which the bias current is fed in the central point of a one-dimensional junction. Such junction configuration has been recently used to detect...

  8. Bias-correction in vector autoregressive models

    DEFF Research Database (Denmark)

    Engsted, Tom; Pedersen, Thomas Quistgaard

    2014-01-01

    We analyze the properties of various methods for bias-correcting parameter estimates in both stationary and non-stationary vector autoregressive models. First, we show that two analytical bias formulas from the existing literature are in fact identical. Next, based on a detailed simulation study,...

  9. Reducing status quo bias in choice experiments

    DEFF Research Database (Denmark)

    Bonnichsen, Ole; Ladenburg, Jacob

    In stated preference literature, the tendency to choose the alternative representing the status quo situation seems to exceed real life status quo effects. Accordingly, status quo bias can be a problem. In Choice Experiments, status quo bias is found to be strongly correlated with protest attitudes...

  10. Comparative Analysis of Codon Usage Bias Patterns in Microsporidian Genomes.

    Directory of Open Access Journals (Sweden)

    Heng Xiang

    Full Text Available The sub-3 Mbp genomes from microsporidian species of the Encephalitozoon genus are the smallest known among eukaryotes and paragons of genomic reduction and compaction in parasites. However, their diminutive stature is not characteristic of all Microsporidia, whose genome sizes vary by an order of magnitude. This large variability suggests that different evolutionary forces are applied on the group as a whole. In this study, we have compared the codon usage bias (CUB between eight taxonomically distinct microsporidian genomes: Encephalitozoon intestinalis, Encephalitozoon cuniculi, Spraguea lophii, Trachipleistophora hominis, Enterocytozoon bieneusi, Nematocida parisii, Nosema bombycis and Nosema ceranae. While the CUB was found to be weak in all eight Microsporidia, nearly all (98% of the optimal codons in S. lophii, T. hominis, E. bieneusi, N. parisii, N. bombycis and N. ceranae are fond of A/U in third position whereas most (64.6% optimal codons in the Encephalitozoon species E. intestinalis and E. cuniculi are biased towards G/C. Although nucleotide composition biases are likely the main factor driving the CUB in Microsporidia according to correlation analyses, directed mutational pressure also likely affects the CUB as suggested by ENc-plots, correspondence and neutrality analyses. Overall, the Encephalitozoon genomes were found to be markedly different from the other microsporidians and, despite being the first sequenced representatives of this lineage, are uncharacteristic of the group as a whole. The disparities observed cannot be attributed solely to differences in host specificity and we hypothesize that other forces are at play in the lineage leading to Encephalitozoon species.

  11. Parameter estimation with an iterative version of the adaptive Gaussian mixture filter

    Science.gov (United States)

    Stordal, A.; Lorentzen, R.

    2012-04-01

    The adaptive Gaussian mixture filter (AGM) was introduced in Stordal et. al. (ECMOR 2010) as a robust filter technique for large scale applications and an alternative to the well known ensemble Kalman filter (EnKF). It consists of two analysis steps, one linear update and one weighting/resampling step. The bias of AGM is determined by two parameters, one adaptive weight parameter (forcing the weights to be more uniform to avoid filter collapse) and one pre-determined bandwidth parameter which decides the size of the linear update. It has been shown that if the adaptive parameter approaches one and the bandwidth parameter decrease with increasing sample size, the filter can achieve asymptotic optimality. For large scale applications with a limited sample size the filter solution may be far from optimal as the adaptive parameter gets close to zero depending on how well the samples from the prior distribution match the data. The bandwidth parameter must often be selected significantly different from zero in order to make large enough linear updates to match the data, at the expense of bias in the estimates. In the iterative AGM we take advantage of the fact that the history matching problem is usually estimation of parameters and initial conditions. If the prior distribution of initial conditions and parameters is close to the posterior distribution, it is possible to match the historical data with a small bandwidth parameter and an adaptive weight parameter that gets close to one. Hence the bias of the filter solution is small. In order to obtain this scenario we iteratively run the AGM throughout the data history with a very small bandwidth to create a new prior distribution from the updated samples after each iteration. After a few iterations, nearly all samples from the previous iteration match the data and the above scenario is achieved. A simple toy problem shows that it is possible to reconstruct the true posterior distribution using the iterative version of

  12. Composite biasing in Monte Carlo radiative transfer

    CERN Document Server

    Baes, Maarten; Lunttila, Tuomas; Bianchi, Simone; Camps, Peter; Juvela, Mika; Kuiper, Rolf

    2016-01-01

    Biasing or importance sampling is a powerful technique in Monte Carlo radiative transfer, and can be applied in different forms to increase the accuracy and efficiency of simulations. One of the drawbacks of the use of biasing is the potential introduction of large weight factors. We discuss a general strategy, composite biasing, to suppress the appearance of large weight factors. We use this composite biasing approach for two different problems faced by current state-of-the-art Monte Carlo radiative transfer codes: the generation of photon packages from multiple components, and the penetration of radiation through high optical depth barriers. In both cases, the implementation of the relevant algorithms is trivial and does not interfere with any other optimisation techniques. Through simple test models, we demonstrate the general applicability, accuracy and efficiency of the composite biasing approach. In particular, for the penetration of high optical depths, the gain in efficiency is spectacular for the spe...

  13. Galaxy Bias in Quintessence Cosmological Models

    CERN Document Server

    Basilakos, S

    2003-01-01

    We derive the evolution of the linear bias factor, $b(z)$, in cosmological models driven by an exotic fluid with an equation of state: $p_{x}=w\\rho_{x}$, where $-1\\le w<0$ (quintessence). Our aim is to put constrains on different cosmological and biasing models by combining the recent observational clustering results of optical ({\\em 2dF}) galaxies (Hawkings et al.) with those predicted by the models. We find that our bias model when fitted to the {\\em 2dF} clustering results predicts different bias evolution for different values of $w$. The models that provide the weak biasing ($b_{\\circ} \\sim 1.1$) of optical galaxies found in many recent observational studies are flat, $\\Omega_{\\rm m}=0.3$ with $w\\le -0.9$. These models however, predict a weak redshift evolution of $b(z)$, not corroborated by N-body simulations.

  14. Adaptation Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Huq, Saleemul

    2011-11-15

    Efforts to help the world's poor will face crises in coming decades as climate change radically alters conditions. Action Research for Community Adapation in Bangladesh (ARCAB) is an action-research programme on responding to climate change impacts through community-based adaptation. Set in Bangladesh at 20 sites that are vulnerable to floods, droughts, cyclones and sea level rise, ARCAB will follow impacts and adaptation as they evolve over half a century or more. National and international 'research partners', collaborating with ten NGO 'action partners' with global reach, seek knowledge and solutions applicable worldwide. After a year setting up ARCAB, we share lessons on the programme's design and move into our first research cycle.

  15. Adaptive ethnography

    DEFF Research Database (Denmark)

    Berth, Mette

    2005-01-01

    This paper focuses on the use of an adaptive ethnography when studying such phenomena as young people's use of mobile media in a learning perspective. Mobile media such as PDAs and mobile phones have a number of affordances which make them potential tools for learning. However, before we begin...... formal and informal learning contexts. The paper also proposes several adaptive methodological techniques for studying young people's interaction with mobiles....... to design and develop educational materials for mobile media platforms we must first understand everyday use and behaviour with a medium such as a mobile phone. The paper outlines the research design for a PhD project on mobile learning which focuses on mobile phones as a way to bridge the gap between...

  16. Hedonic "adaptation"

    Directory of Open Access Journals (Sweden)

    Paul Rozin

    2008-02-01

    Full Text Available People live in a world in which they are surrounded by potential disgust elicitors such as ``used'' chairs, air, silverware, and money as well as excretory activities. People function in this world by ignoring most of these, by active avoidance, reframing, or adaptation. The issue is particularly striking for professions, such as morticians, surgeons, or sanitation workers, in which there is frequent contact with major disgust elicitors. In this study, we study the ``adaptation'' process to dead bodies as disgust elicitors, by measuring specific types of disgust sensitivity in medical students before and after they have spent a few months dissecting a cadaver. Using the Disgust Scale, we find a significant reduction in disgust responses to death and body envelope violation elicitors, but no significant change in any other specific type of disgust. There is a clear reduction in discomfort at touching a cold dead body, but not in touching a human body which is still warm after death.

  17. Sample preparation method for scanning force microscopy

    CERN Document Server

    Jankov, I R; Szente, R N; Carreno, M N P; Swart, J W; Landers, R

    2001-01-01

    We present a method of sample preparation for studies of ion implantation on metal surfaces. The method, employing a mechanical mask, is specially adapted for samples analysed by Scanning Force Microscopy. It was successfully tested on polycrystalline copper substrates implanted with phosphorus ions at an acceleration voltage of 39 keV. The changes of the electrical properties of the surface were measured by Kelvin Probe Force Microscopy and the surface composition was analysed by Auger Electron Spectroscopy.

  18. Collision Sensing Using Force/Torque Sensor

    OpenAIRE

    Yu-Quan Leng; Zheng-Cang Chen; Xu He; Yang Zhang; Wei Zhang

    2016-01-01

    Collision sensing including collision position, collision direction, and force size could make robots smoothly interact with environment, so that the robots can strongly adapt to the outside world. Skin sensor imitates principles of human skin using special material and physical structure to obtain collision information, but this method has some disadvantages, such as complex design, low sampling rate, and poor generality. In this paper, a new method using force/torque sensor to calculate col...

  19. Adaptive noise

    OpenAIRE

    Viney, Mark; Reece, Sarah E.

    2013-01-01

    In biology, noise implies error and disorder and is therefore something which organisms may seek to minimize and mitigate against. We argue that such noise can be adaptive. Recent studies have shown that gene expression can be noisy, noise can be genetically controlled, genes and gene networks vary in how noisy they are and noise generates phenotypic differences among genetically identical cells. Such phenotypic differences can have fitness benefits, suggesting that evolution can shape noise ...

  20. Adaptable positioner

    International Nuclear Information System (INIS)

    This paper describes the circuits and programs in assembly language, developed to control the two DC motors that give mobility to a mechanical arm with two degrees of freedom. As a whole, the system is based in a adaptable regulator designed around a 8 bit microprocessor that, starting from a mode of regulation based in the successive approximation method, evolve to another mode through which, only one approximation is sufficient to get the right position of each motor. (Author) 22 fig. 6 ref

  1. Anhysteretic and biased first magnetization curves for Finemet-type toroidal samples

    Science.gov (United States)

    Varga, L. K.; Kovács, Gy.; Takács, J.

    The anhysteretic and a set of biased first magnetization (BFMC) curves together with a set of first-order reversal curves (FORC) were measured and modeled by the hyperbolic T( x) model for a Finemet-type nanocrystalline toroidal sample with a round hysteresis loop. Similar to the FORC diagram, a "fingerprint"-like distribution has been obtained from a set of BFMC curves using the mixed second-derivate method of Pike. It is concluded that while the FORC diagram gives the distribution of coercive fields (or Preisach distribution), the BFMC diagram gives the distribution of the critical field where the domain wall magnetization become unstable and split up.

  2. Investigating the mechanisms of seasonal ENSO phase locking bias in the ACCESS coupled model

    Science.gov (United States)

    Rashid, Harun A.; Hirst, Anthony C.

    2016-02-01

    between the thermocline feedbacks simulated by ACCESS1.0 and ACCESS1.3 that appear to reinforce the seasonal ENSO phase locking bias in the latter model. We discuss a mechanism by which the thermocline feedback differences could arise from atmospheric forcing differences in the two models.

  3. Adaptation and creativity in cultural context

    Directory of Open Access Journals (Sweden)

    Leonora M. Cohen

    2012-06-01

    Full Text Available Adaptation is the fit between the individual and the environment. The dynamic interplay between person, culture, and environment is one of the most important issues in analyzing creativity. Adaptation is defined as the fit or adjustment of the individual to external conditions, but adaptation can also mean moving from one environment to another more suitable, or even forcing the environment to adapt in response to creative efforts. Culture impacts creativity in limiting acceptable boundaries, yet providing the artifacts used in creating. Culture is impacted and changed by creative efforts. Tight conformity to confining environments or cultures can stifle. The creator must be aware of cultural values and not overstep these boundaries for work to be accepted. A developmental continuum of adaptive, creative behaviors suggests a shift from individual adaptation to the environment to adaptation by the world to the individual.

  4. Indirect adaptive output feedback control of a biorobotic AUV using pectoral-like mechanical fins

    Energy Technology Data Exchange (ETDEWEB)

    Naik, Mugdha S; Singh, Sahjendra N [Department of Electrical and Computer Engineering, University of Nevada, Las Vegas, NV 89154-4026 (United States); Mittal, Rajat [Department of Mechanical and Aerospace Engineering, George Washington University, Washington University, DC 22052 (United States)], E-mail: sahaj@egr.unlv.edu

    2009-06-01

    This paper treats the question of servoregulation of autonomous underwater vehicles (AUVs) in the yaw plane using pectoral-like mechanical fins. The fins attached to the vehicle have oscillatory swaying and yawing motion. The bias angle of the angular motion of the fin is used for the purpose of control. Of course, the design approach considered here is applicable to AUVs for other choices of oscillation patterns of the fins, which produce periodic forces and moments. It is assumed that the vehicle parameters, hydrodynamic coefficients, as well the fin forces and moments are unknown. For the trajectory control of the yaw angle, a sampled-data indirect adaptive control system using output (yaw angle) feedback is derived. The control system has a modular structure, which includes a parameter identifier and a stabilizer. For the control law derivation, an internal model of the exosignals (reference signal (constant or ramp) and constant disturbance) is included. Unlike the direct adaptive control scheme, the derived control law is applicable to minimum as well as nonminimum phase biorobotic AUVs (BAUVs). This is important, because for most of the fin locations on the vehicle, the model is a nonminimum phase. In the closed-loop system, the yaw angle trajectory tracking error converges to zero and the remaining state variables remain bounded. Simulation results are presented which show that the derived modular control system accomplishes precise set point yaw angle control and turning maneuvers in spite of the uncertainties in the system parameters using only yaw angle feedback.

  5. Indirect adaptive output feedback control of a biorobotic AUV using pectoral-like mechanical fins.

    Science.gov (United States)

    Naik, Mugdha S; Singh, Sahjendra N; Mittal, Rajat

    2009-06-01

    This paper treats the question of servoregulation of autonomous underwater vehicles (AUVs) in the yaw plane using pectoral-like mechanical fins. The fins attached to the vehicle have oscillatory swaying and yawing motion. The bias angle of the angular motion of the fin is used for the purpose of control. Of course, the design approach considered here is applicable to AUVs for other choices of oscillation patterns of the fins, which produce periodic forces and moments. It is assumed that the vehicle parameters, hydrodynamic coefficients, as well the fin forces and moments are unknown. For the trajectory control of the yaw angle, a sampled-data indirect adaptive control system using output (yaw angle) feedback is derived. The control system has a modular structure, which includes a parameter identifier and a stabilizer. For the control law derivation, an internal model of the exosignals (reference signal (constant or ramp) and constant disturbance) is included. Unlike the direct adaptive control scheme, the derived control law is applicable to minimum as well as nonminimum phase biorobotic AUVs (BAUVs). This is important, because for most of the fin locations on the vehicle, the model is a nonminimum phase. In the closed-loop system, the yaw angle trajectory tracking error converges to zero and the remaining state variables remain bounded. Simulation results are presented which show that the derived modular control system accomplishes precise set point yaw angle control and turning maneuvers in spite of the uncertainties in the system parameters using only yaw angle feedback.

  6. Indirect adaptive output feedback control of a biorobotic AUV using pectoral-like mechanical fins

    International Nuclear Information System (INIS)

    This paper treats the question of servoregulation of autonomous underwater vehicles (AUVs) in the yaw plane using pectoral-like mechanical fins. The fins attached to the vehicle have oscillatory swaying and yawing motion. The bias angle of the angular motion of the fin is used for the purpose of control. Of course, the design approach considered here is applicable to AUVs for other choices of oscillation patterns of the fins, which produce periodic forces and moments. It is assumed that the vehicle parameters, hydrodynamic coefficients, as well the fin forces and moments are unknown. For the trajectory control of the yaw angle, a sampled-data indirect adaptive control system using output (yaw angle) feedback is derived. The control system has a modular structure, which includes a parameter identifier and a stabilizer. For the control law derivation, an internal model of the exosignals (reference signal (constant or ramp) and constant disturbance) is included. Unlike the direct adaptive control scheme, the derived control law is applicable to minimum as well as nonminimum phase biorobotic AUVs (BAUVs). This is important, because for most of the fin locations on the vehicle, the model is a nonminimum phase. In the closed-loop system, the yaw angle trajectory tracking error converges to zero and the remaining state variables remain bounded. Simulation results are presented which show that the derived modular control system accomplishes precise set point yaw angle control and turning maneuvers in spite of the uncertainties in the system parameters using only yaw angle feedback

  7. Adaptive Landing Gear: Optimum Control Strategy and Potential for Improvement

    OpenAIRE

    Grzegorz Mikułowski; Łukasz Jankowski

    2009-01-01

    An adaptive landing gear is a landing gear (LG) capable of active adaptation to particular landing conditions by means of controlled hydraulic force. The objective of the adaptive control is to mitigate the peak force transferred to the aircraft structure during touch-down, and thus to limit the structural fatigue factor. This paper investigates the ultimate limits for improvement due to various strategies of active control. Five strategies are proposed and investigated numerically using a~va...

  8. Weight Bias in University Health Professions Students.

    Science.gov (United States)

    Blanton, Cynthia; Brooks, Jennifer K; McKnight, Laura

    2016-01-01

    Negative attitudes toward people with high body weight have been documented in pre-professional health students, prompting concern that such feelings may manifest as poor patient care in professional practice. This study assessed weight bias in university students in the non-physician health professions. A convenience sample of 206 students completed an online survey composed of a validated 14-item scale (1-5 lowest to highest weight bias) and questions regarding personal experiences of weight bias. Respondents were grouped by discipline within graduate and undergraduate levels. Weight bias was present in a majority of respondents. Overall, the percentage of responses indicative of weight bias was 92.7%. The mean total score was 3.65. ± 0.52, and the rating exceeded 3 for all 14 scale descriptors of high-weight people. In graduate students, discipline had a significant main effect on total score (p=0.01), with lower scores in dietetics (3.17 ± 0.46) vs audiology/sign language/speech language pathology (3.84 ± 0.41) and physician assistant students (3.78 ± 0.51; pweight bias is prevalent in health professions students at a mountain west university. Well-controlled studies that track students into professional practice would help determine whether bias-reduction interventions in college improve provider behaviors and clinical outcomes. PMID:27585618

  9. Theoretical analysis and an improvement method of the bias effect on the linearity of RF linear power amplifiers

    Institute of Scientific and Technical Information of China (English)

    Wu Tuo; Chen Hongyi; Qian Dahong

    2009-01-01

    Based on the Gummel-Poon model of BJT, the change of the DC bias as a function of the AC input signal in RF linear power amplifiers is theoretically derived, so that the linearity of different DC bias circuits can be interpreted and compared. According to the analysis results, a quantitative adaptive DC bias circuit is proposed,which can improve the linearity and efficiency. From the simulation and test results, we draw conclusions on how to improve the design of linear power amplifier.

  10. Malaysia and forced migration

    OpenAIRE

    Arzura Idris

    2012-01-01

    This paper analyzes the phenomenon of “forced migration” in Malaysia. It examines the nature of forced migration, the challenges faced by Malaysia, the policy responses and their impact on the country and upon the forced migrants. It considers forced migration as an event hosting multifaceted issues related and relevant to forced migrants and suggests that Malaysia has been preoccupied with the issue of forced migration movements. This is largely seen in various responses invoked from Malaysi...

  11. Handbook of force transducers

    CERN Document Server

    Stefanescu, Dan Mihai

    2011-01-01

    Part I introduces the basic ""Principles and Methods of Force Measurement"" acording to a classification into a dozen of force transducers types: resistive, inductive, capacitive, piezoelectric, electromagnetic, electrodynamic, magnetoelastic, galvanomagnetic (Hall-effect), vibrating wires, (micro)resonators, acoustic and gyroscopic. Two special chapters refer to force balance techniques and to combined methods in force measurement. Part II discusses the ""(Strain Gauge) Force Transducers Components"", evolving from the classical force transducer to the digital / intelligent one, with the inco

  12. Effects of long-term meditation practice on attentional biases towards emotional faces: An eye-tracking study.

    Science.gov (United States)

    Pavlov, S V; Korenyok, V V; Reva, N V; Tumyalis, A V; Loktev, K V; Aftanas, L I

    2015-01-01

    Attentional biases towards affective stimuli reflect an individual balance of appetitive and aversive motivational systems. Vigilance in relation to threatening information reflects emotional imbalance, associated with affective and somatic problems. It is known that meditation practice significantly improves control of attention, which is considered to be a tool for adaptive emotional regulation. In this regard, the main aim of the present study was to evaluate the influence of meditation on attentional bias towards neutral and emotional facial expressions. Eyes were tracked while 21 healthy controls and 23 experienced meditators (all males) viewed displays consisting of four facial expressions (neutral, angry, fearful and happy) for 10 s. Measures of biases in initial orienting and maintenance of attention were assessed. No effects were found for initial orienting biases. Meditators spent significantly less time viewing angry and fearful faces than control subjects. Furthermore, meditators selectively attended to happy faces whereas control subjects showed attentional biases towards both angry and happy faces. In sum we can conclude that long-term meditation practice adaptively affects attentional biases towards motivationally significant stimuli and that these biases reflect positive mood and predominance of appetitive motivation. PMID:25109832

  13. Reference List About Implicit and Unconscious Bias

    DEFF Research Database (Denmark)

    Munar, Ana Maria; Villeseche, Florence; Weidemann, Cecilie Dam

    and knowledge base on diversity- and inclusion-related topics. An implicit and/or unconscious bias is a bias that we are unaware of and is therefore expressed unwillingly and unknowingly. As recent studies on implicit bias indicate “we now know that the operation of prejudice and stereotyping in social judgment...... to publications accessible through the CBS library website and/or specifications of where and how to access each publication. In addition, as part of this effort and in line with the task list of the Council for Diversity and Inclusion, the report “Gender and Leadership Practices at Copenhagen Business School...

  14. Forecast Bias Correction: A Second Order Method

    CERN Document Server

    Crowell, Sean

    2010-01-01

    The difference between a model forecast and actual observations is called forecast bias. This bias is due to either incomplete model assumptions and/or poorly known parameter values and initial/boundary conditions. In this paper we discuss a method for estimating corrections to parameters and initial conditions that would account for the forecast bias. A set of simple experiments with the logistic ordinary differential equation is performed using an iterative version of a first order version of our method to compare with the second order version of the method.

  15. Vision is adapted to the natural level of blur present in the retinal image.

    Directory of Open Access Journals (Sweden)

    Lucie Sawides

    Full Text Available BACKGROUND: The image formed by the eye's optics is inherently blurred by aberrations specific to an individual's eyes. We examined how visual coding is adapted to the optical quality of the eye. METHODS AND FINDINGS: We assessed the relationship between perceived blur and the retinal image blur resulting from high order aberrations in an individual's optics. Observers judged perceptual blur in a psychophysical two-alternative forced choice paradigm, on stimuli viewed through perfectly corrected optics (using a deformable mirror to compensate for the individual's aberrations. Realistic blur of different amounts and forms was computer simulated using real aberrations from a population. The blur levels perceived as best focused were close to the levels predicted by an individual's high order aberrations over a wide range of blur magnitudes, and were systematically biased when observers were instead adapted to the blur reproduced from a different observer's eye. CONCLUSIONS: Our results provide strong evidence that spatial vision is calibrated for the specific blur levels present in each individual's retinal image and that this adaptation at least partly reflects how spatial sensitivity is normalized in the neural coding of blur.

  16. Accounting for Unobservable Exposure Time Bias Wh...

    Data.gov (United States)

    U.S. Department of Health & Human Services — Accounting for Unobservable Exposure Time Bias When Using Medicare Prescription Drug Data Unobservable exposure time is common among Medicare Part D beneficiaries,...

  17. Statistical framework for estimating GNSS bias

    CERN Document Server

    Vierinen, Juha; Rideout, William C; Erickson, Philip J; Norberg, Johannes

    2015-01-01

    We present a statistical framework for estimating global navigation satellite system (GNSS) non-ionospheric differential time delay bias. The biases are estimated by examining differences of measured line integrated electron densities (TEC) that are scaled to equivalent vertical integrated densities. The spatio-temporal variability, instrumentation dependent errors, and errors due to inaccurate ionospheric altitude profile assumptions are modeled as structure functions. These structure functions determine how the TEC differences are weighted in the linear least-squares minimization procedure, which is used to produce the bias estimates. A method for automatic detection and removal of outlier measurements that do not fit into a model of receiver bias is also described. The same statistical framework can be used for a single receiver station, but it also scales to a large global network of receivers. In addition to the Global Positioning System (GPS), the method is also applicable to other dual frequency GNSS s...

  18. Bootstrap bias-adjusted GMM estimators

    OpenAIRE

    Ramalho, Joaquim J.S.

    2005-01-01

    The ability of six alternative bootstrap methods to reduce the bias of GMM parameter estimates is examined in an instrumental variable framework using Monte Carlo analysis. Promising results were found for the two bootstrap estimators suggested in the paper.

  19. Physicists' Forced Migrations under Hitler

    Science.gov (United States)

    Beyerchen, Alan

    2011-03-01

    When the Nazis came to power in early 1933 they initiated formal and informal measures that forced Jews and political opponents from public institutions such as universities. Some physicists retired and others went into industry, but most emigrated. International communication and contact made emigration a viable option despite the desperate economic times in the Great Depression. Another wave of emigrations followed the annexation of Austria in 1938. Individual cases as well as general patterns of migration and adaptation to new environments will be examined in this presentation. One important result of the forced migrations was that many of the physicists expelled under Hitler played important roles in strengthening physics elsewhere, often on the Allied side in World War II.

  20. Time Series Properties of Expectation Biases

    OpenAIRE

    Kinari, Yusuke

    2011-01-01

    This study exammes time senes properties of expectation biases usmg a highfrequency survey on stock price forecasts, which required participants to forecast the Nikkei 225 over three forecasting horizons: one day, one week, and one month ahead. Constructing proxies for overconfidence and optimism as the expectation biases, this study shows that overconfidence is likely to remain stable over time while optimism is not. Moreover, a relationship exists between optimism and stock price movement, ...

  1. Biased liquid crystal photonic bandgap fiber

    DEFF Research Database (Denmark)

    Weirich, Johannes; Lægsgaard, Jesper; Alkeskjold, Thomas Tanggaard;

    2008-01-01

    We simulate the director structure of all capillaries in a biased photonic crystal fiber infiltrated with liquid crystals. Various mode simulations for different capillaries show the necessity to consider the entire structure.......We simulate the director structure of all capillaries in a biased photonic crystal fiber infiltrated with liquid crystals. Various mode simulations for different capillaries show the necessity to consider the entire structure....

  2. Constraints on Assembly Bias from Galaxy Clustering

    OpenAIRE

    Zentner, Andrew R.; Hearin, Andrew; Bosch, Frank C. van den; Lange, Johannes U.; Villarreal, Antonio

    2016-01-01

    We constrain the newly-introduced decorated Halo Occupation Distribution (HOD) model using SDSS DR7 measurements of projected galaxy clustering or r-band luminosity threshold samples. The decorated HOD is a model for the galaxy-halo connection that augments the HOD by allowing for the possibility of galaxy assembly bias: galaxy luminosity may be correlated with dark matter halo properties besides mass, Mvir. We demonstrate that it is not possible to rule out galaxy assembly bias using DR7 mea...

  3. Local Bias and Stock Market Conditions

    OpenAIRE

    Giannetti, Mariassunta; Laeven, Luc

    2012-01-01

    We show that the local bias in U.S. mutual fund portfolios varies significantly over time and is more pronounced at times of heightened market uncertainty, such as during financial crises. Similarly, the local bias is less pronounced in periods when market sentiment is strong. These results do not depend on past fund performance or fund inflows during good times. Additionally, we do not find that fund managers earn superior returns on local stocks during periods of heightened market uncertain...

  4. Spending Biased Legislators - Discipline Through Disagreement

    OpenAIRE

    Facundo Piguillem; Alessandro Riboni

    2013-01-01

    This paper studies politicians who have a present-bias for spending; they want to increase current spending and procrastinate spending cuts. We argue that legislators' bias is more severe in economies with low institutional quality. We show that disagreement in legislatures leads to policy persistence and that this attenuates the temptation to overspend. Depending on the environment, legislators' decisions to be fiscally responsible may either complement or substitute other legislator's decis...

  5. Clustering coefficient without degree correlations biases

    OpenAIRE

    Soffer, Sara Nadiv; Vazquez, Alexei

    2004-01-01

    The clustering coefficient quantifies how well connected are the neighbors of a vertex in a graph. In real networks it decreases with the vertex degree, which has been taken as a signature of the network hierarchical structure. Here we show that this signature of hierarchical structure is a consequence of degree correlation biases in the clustering coefficient definition. We introduce a new definition in which the degree correlation biases are filtered out, and provide evidence that in real n...

  6. The Local Bias of Individual Investors

    OpenAIRE

    Ning Zhu

    2002-01-01

    This study investigates individual investors' bias towards nearby companies. Using data from a large U.S. discount brokerage, we find that individual investors tend to invest in companies closer to them relative to the market portfolio. Unlike Coval and Moskowitz's (1999) findings on institutional investors, however, we find that advantageous information cannot explain individual investors' local bias. Accounting numbers and information asymmetry matter less to individual investors' local bia...

  7. Resolving Bias in Laser Ablation Geochronology

    Science.gov (United States)

    Bowring, James; Horstwood, Matthew; Gehrels, George

    2013-06-01

    Increasingly, scientific investigations requiring geochronology utilize laser ablation (LA)-inductively coupled plasma mass spectrometry (ICPMS), taking advantage of the efficiency and throughput possible for uranium-thorium-lead (U-Th-Pb) dating. A number of biases exist when comparing data among laboratories and an ongoing community-based effort is working to resolve and eliminate these biases to improve the accuracy of scientific interpretation based on these data.

  8. Adaptive compressive sensing camera

    Science.gov (United States)

    Hsu, Charles; Hsu, Ming K.; Cha, Jae; Iwamura, Tomo; Landa, Joseph; Nguyen, Charles; Szu, Harold

    2013-05-01

    We have embedded Adaptive Compressive Sensing (ACS) algorithm on Charge-Coupled-Device (CCD) camera based on the simplest concept that each pixel is a charge bucket, and the charges comes from Einstein photoelectric conversion effect. Applying the manufactory design principle, we only allow altering each working component at a minimum one step. We then simulated what would be such a camera can do for real world persistent surveillance taking into account of diurnal, all weather, and seasonal variations. The data storage has saved immensely, and the order of magnitude of saving is inversely proportional to target angular speed. We did design two new components of CCD camera. Due to the matured CMOS (Complementary metal-oxide-semiconductor) technology, the on-chip Sample and Hold (SAH) circuitry can be designed for a dual Photon Detector (PD) analog circuitry for changedetection that predicts skipping or going forward at a sufficient sampling frame rate. For an admitted frame, there is a purely random sparse matrix [Φ] which is implemented at each bucket pixel level the charge transport bias voltage toward its neighborhood buckets or not, and if not, it goes to the ground drainage. Since the snapshot image is not a video, we could not apply the usual MPEG video compression and Hoffman entropy codec as well as powerful WaveNet Wrapper on sensor level. We shall compare (i) Pre-Processing FFT and a threshold of significant Fourier mode components and inverse FFT to check PSNR; (ii) Post-Processing image recovery will be selectively done by CDT&D adaptive version of linear programming at L1 minimization and L2 similarity. For (ii) we need to determine in new frames selection by SAH circuitry (i) the degree of information (d.o.i) K(t) dictates the purely random linear sparse combination of measurement data a la [Φ]M,N M(t) = K(t) Log N(t).

  9. On Comparison of Adaptive Regularization Methods

    DEFF Research Database (Denmark)

    Sigurdsson, Sigurdur; Larsen, Jan; Hansen, Lars Kai

    2000-01-01

    Modeling with flexible models, such as neural networks, requires careful control of the model complexity and generalization ability of the resulting model which finds expression in the ubiquitous bias-variance dilemma. Regularization is a tool for optimizing the model structure reducing variance...... at the expense of introducing extra bias. The overall objective of adaptive regularization is to tune the amount of regularization ensuring minimal generalization error. Regularization is a supplement to direct model selection techniques like step-wise selection and one would prefer a hybrid scheme; however......, a very flexible regularization may substitute the need for selection procedures. This paper investigates recently suggested adaptive regularization schemes. Some methods focus directly on minimizing an estimate of the generalization error (either algebraic or empirical), whereas others start from...

  10. Constraints on Assembly Bias from Galaxy Clustering

    CERN Document Server

    Zentner, Andrew R; Bosch, Frank C van den; Lange, Johannes U; Villarreal, Antonio

    2016-01-01

    We constrain the newly-introduced decorated Halo Occupation Distribution (HOD) model using SDSS DR7 measurements of projected galaxy clustering or r-band luminosity threshold samples. The decorated HOD is a model for the galaxy-halo connection that augments the HOD by allowing for the possibility of galaxy assembly bias: galaxy luminosity may be correlated with dark matter halo properties besides mass, Mvir. We demonstrate that it is not possible to rule out galaxy assembly bias using DR7 measurements of galaxy clustering alone. Moreover, galaxy samples with Mr < -20 and Mr < -20.5 favor strong central galaxy assembly bias. These samples prefer scenarios in which high-concentration are more likely to host a central galaxy relative to low-concentration halos of the same mass. We exclude zero assembly bias with high significance for these samples. Satellite galaxy assembly bias is significant for the faintest sample, Mr < -19. We find no evidence for assembly bias in the Mr < -21 sample. Assembly bi...

  11. Oceanic Climatology in the Coupled Model FGOALS-g2:Improvements and Biases

    Institute of Scientific and Technical Information of China (English)

    LIN Pengfei; YU Yongqiang; LIU Hailong

    2013-01-01

    The present study examines simulated oceanic climatology in the Flexible Global Ocean-Atmosphere-Land System model,Grid-point Version 2 (FGOALS-g2) forced by historical external forcing data.The oceanic temperatures and circulations in FGOALS-g2 were found to be comparable to those observed,and substantially improved compared to those simulated by the previous version,FGOALS-g1.0.Compared with simulations by FGOALS-g1.0,the shallow mixed layer depths were better captured in the eastern Atlantic and Pacific Ocean in FGOALS-g2.In the high latitudes of the Northern Hemisphere,the cold biases of SST were about 1℃ 5℃ smaller in FGOALS-g2.The associated sea ice distributions and their seasonal cycles were more realistic in FGOALS-g2.The pattern of Atlantic Meridional Overturning Circulation (AMOC) was better simulated in FGOALS-g2,although its magnitude was larger than that found in observed data.The simulated Antarctic Circumpolar Current (ACC) transport was about 140 Sv through the Drake Passage,which is close to that observed.Moreover,Antarctic Intermediate Water (AAIW) was better captured in FGOALS-g2.However,large SST cold biases (>3℃) were still found to exist around major western boundary currents and in the Barents Sea,which can be explained by excessively strong oceanic cold advection and unresolved processes owing to the coarse resolution.In the Indo-Pacific warm pool,the cold biases were partly related to the excessive loss of heat from the ocean.Along the eastern coast in the Atlantic and Pacific Oceans,the warm biases were due to overestimation of shortwave radiation.In the Indian Ocean and Southern Ocean,the surface fresh biases were mainly due to the biases of precipitation.In the tropical Pacific Ocean,the surface fresh biases (>2 psu) were mainly caused by excessive precipitation and oceanic advection.In theIndo-Pacific Ocean,fresh biases were also found to dominate in the upper 1000 m,except in the northeastern Indian Ocean.There were warm and

  12. Bias correction of temperature and precipitation data for regional climate model application to the Rhine basin

    Directory of Open Access Journals (Sweden)

    W. Terink

    2009-08-01

    Full Text Available In many climate impact studies hydrological models are forced with meteorological forcing data without an attempt to assess the quality of these forcing data. The objective of this study is to compare downscaled ERA15 (ECMWF-reanalysis data precipitation and temperature with observed precipitation and temperature and apply a bias correction to these forcing variables. The bias-corrected precipitation and temperature data will be used in another study as input for the Variable Infiltration Capacity (VIC model. Observations were available for 134 sub-basins throughout the Rhine basin at a temporal resolution of one day from the International Commission for the Hydrology of the Rhine basin (CHR. Precipitation is corrected by fitting the mean and coefficient of variation (CV of the observations. Temperature is corrected by fitting the mean and standard deviation of the observations. It seems that the uncorrected ERA15 is too warm and too wet for most of the Rhine basin. The bias correction leads to satisfactory results, precipitation and temperature differences decreased significantly. Corrections were largest during summer for both precipitation and temperature, and for September and October for precipitation only. Besides the statistics the correction method was intended to correct for, it is also found to improve the correlations for the fraction of wet days and lag-1 autocorrelations between ERA15 and the observations.

  13. Adaptive Algorithm for Chirp-Rate Estimation

    Directory of Open Access Journals (Sweden)

    Igor Djurović

    2009-01-01

    Full Text Available Chirp-rate, as a second derivative of signal phase, is an important feature of nonstationary signals in numerous applications such as radar, sonar, and communications. In this paper, an adaptive algorithm for the chirp-rate estimation is proposed. It is based on the confidence intervals rule and the cubic-phase function. The window width is adaptively selected to achieve good tradeoff between bias and variance of the chirp-rate estimate. The proposed algorithm is verified by simulations and the results show that it outperforms the standard algorithm with fixed window width.

  14. Combined atomic force microscopy and voltage pulse technique to accurately measure electrostatic force

    Science.gov (United States)

    Inami, Eiichi; Sugimoto, Yoshiaki

    2016-08-01

    We propose a new method of extracting electrostatic force. The technique is based on frequency modulation atomic force microscopy (FM-AFM) combined with a voltage pulse. In this method, the work that the electrostatic field does on the oscillating tip is measured through the cantilever energy dissipation. This allows us to directly extract capacitive forces including the longer range part, to which the conventional FM-AFM is insensitive. The distance-dependent contact potential difference, which is modulated by local charges distributed on the surfaces of the tip and/or sample, could also be correctly obtained. In the absence of local charges, our method can perfectly reproduce the electrostatic force as a function of the distance and the bias voltage. Furthermore, we demonstrate that the system serves as a sensitive sensor enabling us to check the existence of the local charges such as trapped charges and patch charges.

  15. Adaptive management

    DEFF Research Database (Denmark)

    Rist, Lucy; Campbell, Bruce Morgan; Frost, Peter

    2013-01-01

    in scientific articles, policy documents and management plans, but both understanding and application of the concept is mixed. This paper reviews recent literature from conservation and natural resource management journals to assess diversity in how the term is used, highlight ambiguities and consider how...... a management framework, as well as of identified challenges and pathologies, are needed. Further discussion and systematic assessment of the approach is required, together with greater attention to its definition and description, enabling the assessment of new approaches to managing uncertainty, and AM itself.......Adaptive management (AM) emerged in the literature in the mid-1970s in response both to a realization of the extent of uncertainty involved in management, and a frustration with attempts to use modelling to integrate knowledge and make predictions. The term has since become increasingly widely used...

  16. Language adapts to signal disruption in interaction

    OpenAIRE

    Macuch Silva, V.; Roberts, S

    2016-01-01

    Linguistic traits are often seen as reflecting cognitive biases and constraints (e.g. Christiansen & Chater, 2008). However, language must also adapt to properties of the channel through which communication between individuals occurs. Perhaps the most basic aspect of any communication channel is noise. Communicative signals can be blocked, degraded or distorted by other sources in the environment. This poses a fundamental problem for communication. On average, channel disruption accompanies p...

  17. Adaptive optics without altering visual perception

    OpenAIRE

    Koenig,, I.; NW, Hart; HJ, Hofer

    2014-01-01

    Adaptive optics combined with visual psychophysics creates the potential to study the relationship between visual function and the retina at the cellular scale. This potential is hampered, however, by visual interference from the wavefront-sensing beacon used during correction. For example, we have previously shown that even a dim, visible beacon can alter stimulus perception (Hofer, H. J., Blaschke, J., Patolia, J., & Koenig, D. E. (2012). Fixation light hue bias revisited: Implications for ...

  18. Which forcing data errors matter most when modeling seasonal snowpacks?

    Science.gov (United States)

    Raleigh, M. S.; Lundquist, J. D.; Clark, M. P.

    2014-12-01

    High quality forcing data are critical when modeling seasonal snowpacks and snowmelt, but their quality is often compromised due to measurement errors or deficiencies in gridded data products (e.g., spatio-temporal interpolation, empirical parameterizations, or numerical weather model outputs). To assess the relative impact of errors in different meteorological forcings, many studies have conducted sensitivity analyses where errors (e.g., bias) are imposed on one forcing at a time and changes in model output are compared. Although straightforward, this approach only considers simplistic error structures and cannot quantify interactions in different meteorological forcing errors (i.e., it assumes a linear system). Here we employ the Sobol' method of global sensitivity analysis, which allows us to test how co-existing errors in six meteorological forcings (i.e., air temperature, precipitation, wind speed, humidity, incoming shortwave and longwave radiation) impact specific modeled snow variables (i.e., peak snow water equivalent, snowmelt rates, and snow disappearance timing). Using the Sobol' framework across a large number of realizations (>100000 simulations annually at each site), we test how (1) the type (e.g., bias vs. random errors), (2) distribution (e.g., uniform vs. normal), and (3) magnitude (e.g., instrument uncertainty vs. field uncertainty) of forcing errors impact key outputs from a physically based snow model (the Utah Energy Balance). We also assess the role of climate by conducting the analysis at sites in maritime, intermountain, continental, and tundra snow zones. For all outputs considered, results show that (1) biases in forcing data are more important than random errors, (2) the choice of error distribution can enhance the importance of specific forcings, and (3) the level of uncertainty considered dictates the relative importance of forcings. While the relative importance of forcings varied with snow variable and climate, the results broadly

  19. Social biases determine spatiotemporal sparseness of ciliate mating heuristics.

    Science.gov (United States)

    Clark, Kevin B

    2012-01-01

    Ciliates become highly social, even displaying animal-like qualities, in the joint presence of aroused conspecifics and nonself mating pheromones. Pheromone detection putatively helps trigger instinctual and learned courtship and dominance displays from which social judgments are made about the availability, compatibility, and fitness representativeness or likelihood of prospective mates and rivals. In earlier studies, I demonstrated the heterotrich Spirostomum ambiguum improves mating competence by effecting preconjugal strategies and inferences in mock social trials via behavioral heuristics built from Hebbian-like associative learning. Heuristics embody serial patterns of socially relevant action that evolve into ordered, topologically invariant computational networks supporting intra- and intermate selection. S. ambiguum employs heuristics to acquire, store, plan, compare, modify, select, and execute sets of mating propaganda. One major adaptive constraint over formation and use of heuristics involves a ciliate's initial subjective bias, responsiveness, or preparedness, as defined by Stevens' Law of subjective stimulus intensity, for perceiving the meaningfulness of mechanical pressures accompanying cell-cell contacts and additional perimating events. This bias controls durations and valences of nonassociative learning, search rates for appropriate mating strategies, potential net reproductive payoffs, levels of social honesty and deception, successful error diagnosis and correction of mating signals, use of insight or analysis to solve mating dilemmas, bioenergetics expenditures, and governance of mating decisions by classical or quantum statistical mechanics. I now report this same social bias also differentially affects the spatiotemporal sparseness, as measured with metric entropy, of ciliate heuristics. Sparseness plays an important role in neural systems through optimizing the specificity, efficiency, and capacity of memory representations. The present

  20. Illinois task force on global climate change

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, B.S. [Illinois Dept. of Natural Resources, Springfield, IL (United States)

    1996-12-31

    The purpose of this report is to document progress in the areas of national policy development, emissions reduction, research and education, and adaptation, and to identify specific actions that will be undertaken to implement the Illinois state action plan. The task force has been tracking national and international climate change policy, and helping shape national policy agenda. Identification and implementation of cost-effective mitigation measures has been performed for emissions reduction. In the area of research and education, the task force is developing the capacity to measure climate change indicators, maintaining and enhancing Illinois relevant research, and strengthening climate change education. Activities relevant to adaptation to new policy include strengthening water laws and planning for adaptation. 6 figs., 4 tabs.

  1. Training Adaptive Decision-Making.

    Energy Technology Data Exchange (ETDEWEB)

    Abbott, Robert G.; Forsythe, James C.

    2014-10-01

    Adaptive Thinking has been defined here as the capacity to recognize when a course of action that may have previously been effective is no longer effective and there is need to adjust strategy. Research was undertaken with human test subjects to identify the factors that contribute to adaptive thinking. It was discovered that those most effective in settings that call for adaptive thinking tend to possess a superior capacity to quickly and effectively generate possible courses of action, as measured using the Category Generation test. Software developed for this research has been applied to develop capabilities enabling analysts to identify crucial factors that are predictive of outcomes in fore-on-force simulation exercises.

  2. Temporal variation in sex allocation in the mealybug Planococcus citri : Adaptation, constraint, or both?

    NARCIS (Netherlands)

    Ross, Laura; Langenhof, Minke B. W.; Pen, Ido; Shuker, David M.

    2012-01-01

    Sex ratio theory has been very successful in predicting under which circumstances parents should bias their investment towards a particular offspring sex. However, most examples of adaptive sex ratio bias come from species with well-defined mating systems and sex determining mechanisms, while in man

  3. Imagery versus verbal interpretive cognitive bias modification for compulsive checking.

    Science.gov (United States)

    Black, Melissa J; Grisham, Jessica R

    2016-08-01

    Pathological doubting and checking is a common symptom presentation in obsessive-compulsive disorder (OCD). Previous research has established that compulsive checkers do not display an actual memory deficit, but lack confidence in their memories and experience intolerance of uncertainty regarding the completion of tasks. We investigated whether interpretive cognitive bias modification (CBM-I) reduced memory distrust and intolerance of uncertainty in a nonclinical sample. We also examined the possible enhancement of CBM-I for OCD through imagery training. The results provide evidence that participants who received positive imagery CBM-I training may have interpreted novel ambiguous checking scenarios more adaptively and endorsed negative checking beliefs less relative to participants in the control imagery CBM-I condition. Findings on behavioural checking tasks did not indicate any specific response to CBM-I training. Future research may translate these suggestive findings into a useful adjunct to traditional strategies targeting maladaptive OCD beliefs. PMID:27300752

  4. Serial monogamy and sex ratio bias in Nazca boobies.

    Science.gov (United States)

    Maness, Terri J; Anderson, David J

    2007-08-22

    Biased operational sex ratios (OSRs) can drive sexual selection on members of the over-represented sex via competition for mates, causing higher variance and skew in reproductive success (RS) among them if an individual's quality is a persistent characteristic. Alternatively, costs of reproduction may degrade breeding performance, creating the opportunity for members of the limiting sex to switch mates adaptively, effectively homogenizing variance and skew in RS among the sex in excess. We tested these two contrasting models in a male-biased population of the Nazca booby (Sula granti) with demonstrated costs of reproduction with data on total RS over a 14-year period. Variances and skews in RS were similar, and males changed from breeder to non-breeder more frequently than females. Under the persistent individual quality model, females should mate only with high quality males, and non-breeding males should seldom enter the breeding pool, yet 45% of non-breeding males (re)entered the breeding pool each year on average. Many Nazca booby females apparently exchange a depleted male for a new mate from the pool of current non-breeder males. Our evidence linking serial monogamy to costs of reproduction is novel and suggests selection on female mating preferences based on an interaction between at least two life-history components (OSR and reproductive effort).

  5. An attempt to target anxiety sensitivity via cognitive bias modification.

    Directory of Open Access Journals (Sweden)

    Elise M Clerkin

    Full Text Available Our goals in the present study were to test an adaptation of a Cognitive Bias Modification program to reduce anxiety sensitivity, and to evaluate the causal relationships between interpretation bias of physiological cues, anxiety sensitivity, and anxiety and avoidance associated with interoceptive exposures. Participants with elevated anxiety sensitivity who endorsed having a panic attack or limited symptom attack were randomly assigned to either an Interpretation Modification Program (IMP; n = 33 or a Control (n = 32 condition. During interpretation modification training (via the Word Sentence Association Paradigm, participants read short sentences describing ambiguous panic-relevant physiological and cognitive symptoms and were trained to endorse benign interpretations and reject threatening interpretations associated with these cues. Compared to the Control condition, IMP training successfully increased endorsements of benign interpretations and decreased endorsements of threatening interpretations at visit 2. Although self-reported anxiety sensitivity decreased from pre-selection to visit 1 and from visit 1 to visit 2, the reduction was not larger for the experimental versus control condition. Further, participants in IMP (vs. Control training did not experience less anxiety and avoidance associated with interoceptive exposures. In fact, there was some evidence that those in the Control condition experienced less avoidance following training. Potential explanations for the null findings, including problems with the benign panic-relevant stimuli and limitations with the control condition, are discussed.

  6. Dopaminergic genes predict individual differences in susceptibility to confirmation bias.

    Science.gov (United States)

    Doll, Bradley B; Hutchison, Kent E; Frank, Michael J

    2011-04-20

    The striatum is critical for the incremental learning of values associated with behavioral actions. The prefrontal cortex (PFC) represents abstract rules and explicit contingencies to support rapid behavioral adaptation in the absence of cumulative experience. Here we test two alternative models of the interaction between these systems, and individual differences thereof, when human subjects are instructed with prior information about reward contingencies that may or may not be accurate. Behaviorally, subjects are overly influenced by prior instructions, at the expense of learning true reinforcement statistics. Computational analysis found that this pattern of data is best accounted for by a confirmation bias mechanism in which prior beliefs--putatively represented in PFC--influence the learning that occurs in the striatum such that reinforcement statistics are distorted. We assessed genetic variants affecting prefrontal and striatal dopaminergic neurotransmission. A polymorphism in the COMT gene (rs4680), associated with prefrontal dopaminergic function, was predictive of the degree to which participants persisted in responding in accordance with prior instructions even as evidence against their veracity accumulated. Polymorphisms in genes associated with striatal dopamine function (DARPP-32, rs907094, and DRD2, rs6277) were predictive of learning from positive and negative outcomes. Notably, these same variants were predictive of the degree to which such learning was overly inflated or neglected when outcomes are consistent or inconsistent with prior instructions. These findings indicate dissociable neurocomputational and genetic mechanisms by which initial biases are strengthened by experience. PMID:21508242

  7. Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

    Science.gov (United States)

    Grover, Amit; Sanjuan-Pla, Alejandra; Thongjuea, Supat; Carrelha, Joana; Giustacchini, Alice; Gambardella, Adriana; Macaulay, Iain; Mancini, Elena; Luis, Tiago C; Mead, Adam; Jacobsen, Sten Eirik W; Nerlov, Claus

    2016-01-01

    Aged haematopoietic stem cells (HSCs) generate more myeloid cells and fewer lymphoid cells compared with young HSCs, contributing to decreased adaptive immunity in aged individuals. However, it is not known how intrinsic changes to HSCs and shifts in the balance between biased HSC subsets each contribute to the altered lineage output. Here, by analysing HSC transcriptomes and HSC function at the single-cell level, we identify increased molecular platelet priming and functional platelet bias as the predominant age-dependent change to HSCs, including a significant increase in a previously unrecognized class of HSCs that exclusively produce platelets. Depletion of HSC platelet programming through loss of the FOG-1 transcription factor is accompanied by increased lymphoid output. Therefore, increased platelet bias may contribute to the age-associated decrease in lymphopoiesis. PMID:27009448

  8. Adaptive Feedback Cancellation With Band-Limited LPC Vocoder in Digital Hearing Aids

    OpenAIRE

    Ma, Guilin; Gran, Fredrik; Jacobsen, Finn; Agerkvist, Finn T.

    2011-01-01

    Feedback oscillation is one of the major issues with hearing aids. An effective way of feedback suppression is adaptive feedback cancellation, which uses an adaptive filter to estimate the feedback path. However, when the external input signal is correlated with the receiver input signal, the estimate of the feedback path is biased. This so-called “bias problem” results in a large modeling error and a cancellation of the desired signal. This paper proposes a band-limited linear predictive cod...

  9. Affective Biases in Humans and Animals.

    Science.gov (United States)

    Robinson, E S J; Roiser, J P

    2016-01-01

    Depression is one of the most common but poorly understood psychiatric conditions. Although drug treatments and psychological therapies are effective in some patients, many do not achieve full remission and some patients receive no apparent benefit. Developing new improved treatments requires a better understanding of the aetiology of symptoms and evaluation of novel therapeutic targets in pre-clinical studies. Recent developments in our understanding of the basic cognitive processes that may contribute to the development of depression and its treatment offer new opportunities for both clinical and pre-clinical research. This chapter discusses the clinical evidence supporting a cognitive neuropsychological model of depression and antidepressant efficacy, and how this information may be usefully translated to pre-clinical investigation. Studies using neuropsychological tests in depressed patients and at risk populations have revealed basic negative emotional biases and disrupted reward and punishment processing, which may also impact on non-affective cognition. These affective biases are sensitive to antidepressant treatments with early onset effects observed, suggesting an important role in recovery. This clinical work into affective biases has also facilitated back-translation to animals and the development of assays to study affective biases in rodents. These animal studies suggest that, similar to humans, rodents in putative negative affective states exhibit negative affective biases on decision-making and memory tasks. Antidepressant treatments also induce positive biases in these rodent tasks, supporting the translational validity of this approach. Although still in the early stages of development and validation, affective biases in depression have the potential to offer new insights into the clinical condition, as well as facilitating the development of more translational approaches for pre-clinical studies. PMID:27660073

  10. Origins of Asymmetric Magnetization Reversal in Exchange Biased Multilayers

    Science.gov (United States)

    Liu, Yang; Wang, Shuoguo; Li, Yang; Chen, Ning; Liu, Shuai; Li, Minghua; Yu, Guanghua; Department of Materials Physics; Chemistry, University of Science; Technology Beijing Team; State Key Laboratory Of Magnetism, Beijing National LaboratoryCondensed Matter Physics, Institu Team; University of Puerto Rico At Mayaguez Team

    2011-03-01

    Novel asymmetric magnetization reversal behaviors (ARBs) as well as positive exchange bias (EB) are observed by using the alternating gradient force magnetometer (AGM) in both Co/FeMn bilayer with an oblique out-of-plane exchange anisotropy and the Co/FeMn bilayer in which Co layer has a quite heavy thickness. There are two different ARBs, arised from the ferromagnetic and the antiferromagnetic layer respectively under the perpendicular magnetization. Our results show that two intrinsic origins of the ARBs (i.e. the competing anisotropy and the inhomogeneity of the magnetic structure) coexist. Both of them are indispensable for the development of the ARBs in our Co/FeMn multilayers. This work was supported by the National Science Foundation under Grant no. DMR-0821284, NASA under Grant Nos. NNX10AM80H and NNX07AO30A.

  11. Deaging and Asymmetric Energy Landscapes in Electrically Biased Ferroelectrics

    Energy Technology Data Exchange (ETDEWEB)

    Tutuncu, Goknur; Damjanovic, Dragan; Chen, Jun; Jones, Jacob L. (Ecole); (UST - China); (Florida)

    2015-09-01

    In ferroic materials, the dielectric, piezoelectric, magnetic, and elastic coefficients are significantly affected by the motion of domain walls. This motion can be described as the propagation of a wall across various types and strengths of pinning centers that collectively constitute a force profile or energetic landscape. Biased domain structures and asymmetric energy landscapes can be created through application of high fields (such as during electrical poling), and the material behavior in such states is often highly asymmetric. In some cases, this behavior can be considered as the electric analogue to the Bauschinger effect. The present Letter uses time-resolved, high-energy x-ray Bragg scattering to probe this asymmetry and the associated deaging effect in the ferroelectric morphotropic phase boundary composition 0.36BiScO{sub 3}-0.64PbTiO{sub 3}.

  12. Kelvin probe force microscopy in liquid using electrochemical force microscopy

    Directory of Open Access Journals (Sweden)

    Liam Collins

    2015-01-01

    Full Text Available Conventional closed loop-Kelvin probe force microscopy (KPFM has emerged as a powerful technique for probing electric and transport phenomena at the solid–gas interface. The extension of KPFM capabilities to probe electrostatic and electrochemical phenomena at the solid–liquid interface is of interest for a broad range of applications from energy storage to biological systems. However, the operation of KPFM implicitly relies on the presence of a linear lossless dielectric in the probe–sample gap, a condition which is violated for ionically-active liquids (e.g., when diffuse charge dynamics are present. Here, electrostatic and electrochemical measurements are demonstrated in ionically-active (polar isopropanol, milli-Q water and aqueous NaCl and ionically-inactive (non-polar decane liquids by electrochemical force microscopy (EcFM, a multidimensional (i.e., bias- and time-resolved spectroscopy method. In the absence of mobile charges (ambient and non-polar liquids, KPFM and EcFM are both feasible, yielding comparable contact potential difference (CPD values. In ionically-active liquids, KPFM is not possible and EcFM can be used to measure the dynamic CPD and a rich spectrum of information pertaining to charge screening, ion diffusion, and electrochemical processes (e.g., Faradaic reactions. EcFM measurements conducted in isopropanol and milli-Q water over Au and highly ordered pyrolytic graphite electrodes demonstrate both sample- and solvent-dependent features. Finally, the feasibility of using EcFM as a local force-based mapping technique of material-dependent electrostatic and electrochemical response is investigated. The resultant high dimensional dataset is visualized using a purely statistical approach that does not require a priori physical models, allowing for qualitative mapping of electrostatic and electrochemical material properties at the solid–liquid interface.

  13. W(h)ither the Oracle? Cognitive biases and other human challenges of integrated environmental modeling

    Science.gov (United States)

    Glynn, Pierre D.; Ames, D.P.; Quinn, N. W. T.; Rizzoli, A.E.

    2014-01-01

    Integrated environmental modeling (IEM) can organize and increase our knowledge of the complex, dynamic ecosystems that house our natural resources and control the quality of our environments. Human behavior, however, must be taken into account. Human biases/heuristics reflect adaptation over our evolutionary past to frequently experienced situations that affected our survival and that provided sharply distinguished feedbacks at the level of the individual. Unfortunately, human behavior is not adapted to the more diffusely experienced, less frequently encountered, problems and issues that IEM typically seeks to address in the simulation of natural resources and environments. While seeking inspiration from the prophetic traditions of the Oracle of Delphi, several human biases are identified that may affect how the science base of IEM is assembled, and how IEM results are interpreted and used. These biases are supported by personal observations, and by the findings of behavioral scientists. A process for critical analysis is proposed that solicits explicit accounting and cognizance of potential human biases. A number of suggestions are made to address the human challenges of IEM, in addition to maintaining attitudes of watchful humility, open-mindedness, honesty, and transparent accountability. These include creating a new area of study in the behavioral biogeosciences, using structured processes for engaging the modeling and stakeholder community in IEM, and using “red teams” to increase resilience of IEM constructs and use.

  14. CD bias control on hole pattern

    Science.gov (United States)

    Koike, Kyohei; Hara, Arisa; Natori, Sakurako; Yamauchi, Shohei; Yamato, Masatoshi; Oyama, Kenichi; Yaegashi, Hidetami

    2016-03-01

    Gridded design rules[1] is major process in configuring logic circuit used 193-immersion lithography. In the scaling of grid patterning, we can make 10nm order line and space pattern by using multiple patterning techniques such as self-aligned multiple patterning (SAMP) and litho-etch- litho-etch (LELE)[2][3][5] . On the other hand, Line cut process has some error parameters such as pattern defect, placement error, roughness and X-Y CD bias with the decreasing scale. Especially roughness and X-Y CD bias are paid attention because it cause cut error and pattern defect. In this case, we applied some smoothing process to care hole roughness[4]. Each smoothing process showed different effect on X-Y CD bias. In this paper, we will report the pattern controllability comparison of trench and block + inverse. It include X-Y CD bias, roughness and process usability. Furthermore we will discuss optimum method focused on X-Y CD bias when we use additional process such as smoothing and shrink etching .

  15. Force propagation and force generation in cells.

    Science.gov (United States)

    Jonas, Oliver; Duschl, Claus

    2010-09-01

    Determining how forces are produced by and propagated through the cytoskeleton (CSK) of the cell is of great interest as dynamic processes of the CSK are intimately correlated with many molecular signaling pathways. We are presenting a novel approach for integrating measurements on cell elasticity, transcellular force propagation, and cellular force generation to obtain a comprehensive description of dynamic and mechanical properties of the CSK under force loading. This approach uses a combination of scanning force microscopy (SFM) and Total Internal Reflection Fluorescence (TIRF) microscopy. We apply well-defined loading schemes onto the apical cell membrane of fibroblasts using the SFM and simultaneously use TIRF microscopy to image the topography of the basal cell membrane. The locally distinct changes of shape and depth of the cytoskeletal imprints onto the basal membrane are interpreted as results of force propagation through the cytoplasm. This observation provides evidence for the tensegrity model and demonstrates the usefulness of our approach that does not depend on potentially disturbing marker compounds. We confirm that the actin network greatly determines cell stiffness and represents the substrate that mediates force transduction through the cytoplasm of the cell. The latter is an essential feature of tensegrity. Most importantly, our new finding that, both intact actin and microtubule networks are required for enabling the cell to produce work, can only be understood within the framework of the tensegrity model. We also provide, for the first time, a direct measurement of the cell's mechanical power output under compression at two femtowatts. PMID:20607861

  16. Thinking in Black and White: Conscious thought increases racially biased judgments through biased face memory

    NARCIS (Netherlands)

    Strick, M.A.; Stoeckart, P.F.; Dijksterhuis, A.J.

    2015-01-01

    It is a common research finding that conscious thought helps people to avoid racial discrimination. These three experiments, however, illustrate that conscious thought may increase biased face memory, which leads to increased judgment bias (i.e., preferring White to Black individuals). In Experiment

  17. Placebo effect studies are susceptible to response bias and to other types of biases

    DEFF Research Database (Denmark)

    Hróbjartsson, Asbjørn; Kaptchuk, Ted J; Miller, Franklin G

    2011-01-01

    Investigations of the effect of placebo are often challenging to conduct and interpret. The history of placebo shows that assessment of its clinical significance has a real potential to be biased. We analyze and discuss typical types of bias in studies on placebo....

  18. Linearity Limits of Biased 1337 Trap Detectors

    CERN Document Server

    Balling, Petr

    2015-01-01

    The upper power limit of linear response of light trap detectors was recently measured [2,3]. We have completed this measurement with test of traps with bias voltage at several visible wavelengths using silicon photodiodes Hamamatsu S1337 1010 and made a brief test of S5227 1010. Bias extends the linearity limit by factor of more than 10 for very narrow beams and more than 30 for wide beams [5]. No irreversible changes were detected even for the highest irradiance of 33 W/cm2 at 406nm. Here we present measurement of minimal bias voltage necessary for 99%, 99.8% and 99.95% linearity for several beam sizes.

  19. Reciprocity-induced bias in digital reputation

    CERN Document Server

    Livan, Giacomo; Aste, Tomaso

    2016-01-01

    The peer-to-peer (P2P) economy relies on establishing trust in distributed networked systems, where the reliability of a user is assessed through digital peer-review processes that aggregate ratings into reputation scores. Here we present evidence of a network effect which biases the digital reputations of the users of P2P networks, showing that P2P networks display exceedingly high levels of reciprocity. In fact, these are so large that they are close to the highest levels structurally compatible with the networks' reputation landscape. This shows that the crowdsourcing process underpinning digital reputation is significantly distorted by the attempt of users to mutually boost reputation, or to retaliate, through the exchange of ratings. We show that the least active users are predominantly responsible for such reciprocity-induced bias, and that this fact can be exploited to suppress the bias itself.

  20. Learning biases predict a word order universal.

    Science.gov (United States)

    Culbertson, Jennifer; Smolensky, Paul; Legendre, Géraldine

    2012-03-01

    How recurrent typological patterns, or universals, emerge from the extensive diversity found across the world's languages constitutes a central question for linguistics and cognitive science. Recent challenges to a fundamental assumption of generative linguistics-that universal properties of the human language acquisition faculty constrain the types of grammatical systems which can occur-suggest the need for new types of empirical evidence connecting typology to biases of learners. Using an artificial language learning paradigm in which adult subjects are exposed to a mix of grammatical systems (similar to a period of linguistic change), we show that learners' biases mirror a word-order universal, first proposed by Joseph Greenberg, which constrains typological patterns of adjective, numeral, and noun ordering. We briefly summarize the results of a probabilistic model of the hypothesized biases and their effect on learning, and discuss the broader implications of the results for current theories of the origins of cross-linguistic word-order preferences. PMID:22208785

  1. Recognition bias and the physical attractiveness stereotype.

    Science.gov (United States)

    Rohner, Jean-Christophe; Rasmussen, Anders

    2012-06-01

    Previous studies have found a recognition bias for information consistent with the physical attractiveness stereotype (PAS), in which participants believe that they remember that attractive individuals have positive qualities and that unattractive individuals have negative qualities, regardless of what information actually occurred. The purpose of this research was to examine whether recognition bias for PAS congruent information is replicable and invariant across a variety of conditions (i.e. generalizable). The effects of nine different moderator variables were examined in two experiments. With a few exceptions, the effect of PAS congruence on recognition bias was independent of the moderator variables. The results suggest that the tendency to believe that one remembers information consistent with the physical attractiveness stereotype is a robust phenomenon. PMID:22416805

  2. Recognition bias and the physical attractiveness stereotype.

    Science.gov (United States)

    Rohner, Jean-Christophe; Rasmussen, Anders

    2012-06-01

    Previous studies have found a recognition bias for information consistent with the physical attractiveness stereotype (PAS), in which participants believe that they remember that attractive individuals have positive qualities and that unattractive individuals have negative qualities, regardless of what information actually occurred. The purpose of this research was to examine whether recognition bias for PAS congruent information is replicable and invariant across a variety of conditions (i.e. generalizable). The effects of nine different moderator variables were examined in two experiments. With a few exceptions, the effect of PAS congruence on recognition bias was independent of the moderator variables. The results suggest that the tendency to believe that one remembers information consistent with the physical attractiveness stereotype is a robust phenomenon.

  3. Racial bias in perceptions of others' pain.

    Directory of Open Access Journals (Sweden)

    Sophie Trawalter

    Full Text Available The present work provides evidence that people assume a priori that Blacks feel less pain than do Whites. It also demonstrates that this bias is rooted in perceptions of status and the privilege (or hardship status confers, not race per se. Archival data from the National Football League injury reports reveal that, relative to injured White players, injured Black players are deemed more likely to play in a subsequent game, possibly because people assume they feel less pain. Experiments 1-4 show that White and Black Americans-including registered nurses and nursing students-assume that Black people feel less pain than do White people. Finally, Experiments 5 and 6 provide evidence that this bias is rooted in perceptions of status, not race per se. Taken together, these data have important implications for understanding race-related biases and healthcare disparities.

  4. Skill-Biased Technological Change in Denmark

    DEFF Research Database (Denmark)

    Malchow-Møller, Nikolaj; Rose Skaksen, Jan

    2003-01-01

    Skill-Biased Technological Change in Denmark:A Disaggregate Perspective@*In this paper, we provide an industry-level analysis of skill-biased technological change(SBTC) in Denmark over the last two decades. The analysis shows that SBTC has variedconsiderably across industries, and traditionally...... large Danish industries have experiencedrelatively less SBTC. This may partly explain why wage inequality between skilled and lessskilled has risen less in Denmark than in other countries. We also find that SBTC has beenconcentrated in already skill-intensive industries. This contains important...... information aboutfuture labour requirements, as the relative importance of these industries must be expectedto grow, thereby reinforcing the shift in demand for skilled labour.JEL Classification: J24, J31, L6Keywords: skill-biased technological change, Danish industries...

  5. Cosmology of biased discrete symmetry breaking

    Science.gov (United States)

    Gelmini, Graciela B.; Gleiser, Marcelo; Kolb, Edward W.

    1988-01-01

    The cosmological consequences of spontaneous breaking of an approximate discrete symmetry are studied. The breaking leads to formation of proto-domains of false and true vacuum separated by domain walls of thickness determined by the mass scale of the model. The cosmological evolution of the walls is extremely sensitive to the magnitude of the biasing; several scenarios are possible, depending on the interplay between the surface tension on the walls and the volume pressure from the biasing. Walls may disappear almost immediately after they form, or may live long enough to dominate the energy density of the Universe and cause power-law inflation. Limits are obtained on the biasing that characterizes each possible scenario.

  6. Motion, identity and the bias toward agency

    Directory of Open Access Journals (Sweden)

    Chris eFields

    2014-08-01

    Full Text Available The well-documented human bias toward agency as a cause and therefore an explanation of observed events is typically attributed to evolutionary selection for a social brain. Based on a review of developmental and adult behavioral and neurocognitive data, it is argued that the bias toward agency is a result of the default human solution, developed during infancy, to the computational requirements of object re-identification over gaps in observation of more than a few seconds. If this model is correct, overriding the bias toward agency to construct mechanistic explanations of observed events requires structure-mapping inferences, implemented by the pre-motor action planning system, that replace agents with mechanisms as causes of unobserved changes in contextual or featural properties of objects. Experiments that would test this model are discussed.

  7. Observational biases in flux magnification measurements

    CERN Document Server

    Hildebrandt, Hendrik

    2015-01-01

    Flux magnification is an interesting complement to shear-based lensing measurements, especially at high redshift where sources are harder to resolve. One measures either changes in the source density (magnification bias) or in the shape of the flux distribution (e.g. magnitude-shift). The interpretation of these measurements relies on theoretical estimates of how the observables change under magnification. Here we present simulations to create multi-band photometric mock catalogues of Lyman-break galaxies in a CFHTLenS-like survey that include several observational effects that can change these relations, making simple theoretical estimates unusable. In particular, we show how the magnification bias can be affected by photometric noise, colour selection, and dust extinction. We find that a simple measurement of the slope of the number-counts is not sufficient for the precise interpretation of virtually all observations of magnification bias. We also explore how sensitive the shift in the mean magnitude of a s...

  8. “Rational” or “Intuitive”: Are Behavioral Biases Correlated Across Stock Market Investors?

    Directory of Open Access Journals (Sweden)

    Andrey Kudryavtsev

    2013-06-01

    Full Text Available Human judgments are systematically affected by various biases and distortions. The main goal of our study is to analyze the effects of five well-documented behavioral biases—namely, the disposition effect, herd behavior, availability heuristic, gambler’s fallacy and hot hand fallacy—on the mechanisms of stock market decision making and, in particular, the correlations between the magnitudes of the biases in the cross-section of market investors. Employing an extensive online survey, we demonstrate that, on average, active capital market investors exhibit moderate degrees of behavioral biases. We then calculate the cross-sectional correlation coefficients between the biases and find that all of them are positive and highly significant for both professional and non-professional investors and for all categories of investors, as classified by their experience levels, genders, and ages. This finding suggests that an investor who is more inclined to employ a certain intuitive decision-making technique will most likely accept other techniques as well. Furthermore, we determine that the correlation coefficients between the biases are higher for more experienced investors and male investors, indicating that these categories of investors are likely to behave more consistently, or, in other words, are more likely to decide for themselves whether to rely on simplifying decision-making techniques in general or to reject all of them. Alternatively, this finding may suggest that these investors develop more sophisticated “adaptive toolboxes”, or collections of heuristics, and apply them more systematically.

  9. System Model Bias Processing Approach for Regional Coordinated States Information Involved Filtering

    Directory of Open Access Journals (Sweden)

    Zebo Zhou

    2016-01-01

    Full Text Available In the Kalman filtering applications, the conventional dynamic model which connects the states information of two consecutive epochs by state transition matrix is usually predefined and assumed to be invariant. Aiming to improve the adaptability and accuracy of dynamic model, we propose multiple historical states involved filtering algorithm. An autoregressive model is used as the dynamic model which is subsequently combined with observation model for deriving the optimal window-recursive filter formulae in the sense of minimum mean square error principle. The corresponding test statistics characteristics of system residuals are discussed in details. The test statistics of regional predicted residuals are then constructed in a time-window for model bias testing with two hypotheses, that is, the null and alternative hypotheses. Based on the innovations test statistics, we develop a model bias processing procedure including bias detection, location identification, and state correction. Finally, the minimum detectable bias and bias-to-noise ratio are both computed for evaluating the internal and external reliability of overall system, respectively.

  10. Bias modulated scanning ion conductance microscopy.

    Science.gov (United States)

    McKelvey, Kim; Perry, David; Byers, Joshua C; Colburn, Alex W; Unwin, Patrick R

    2014-04-01

    Nanopipets are versatile tools for nanoscience, particularly when used in scanning ion conductance microscopy (SICM) to determine, in a noncontact manner, the topography of a sample. We present a new method, applying an oscillating bias between a quasi-reference counter electrode (QRCE) in the SICM nanopipet probe and a second QRCE in the bulk solution, to generate a feedback signal to control the distance between the end of a nanopipet and a surface. Both the amplitude and phase of the oscillating ion current, induced by the oscillating bias and extracted using a phase-sensitive detector, are shown to be sensitive to the probe-surface distance and are used to provide stable feedback signals. The phase signal is particularly sensitive at high frequencies of the oscillating bias (up to 30 kHz herein). This development eliminates the need to physically oscillate the probe to generate an oscillating ion current feedback signal, as needed for conventional SICM modes. Moreover, bias modulation allows a feedback signal to be generated without any net ion current flow, ensuring that any polarization of the quasi reference counter electrodes, electro-osmotic effects, and perturbations of the supporting electrolyte composition are minimized. Both feedback signals, magnitude and phase, are analyzed through approach curve measurements to different surfaces at a range of distinct frequencies and via impedance measurements at different distances from a surface. The bias modulated response is readily understood via a simple equivalent circuit model. Bias modulated (BM)-SICM is compared to conventional SICM imaging through measurements of substrates with distinct topographical features and yields equivalent results. Finally, BM-SICM with both amplitude and phase feedback is used for topographical imaging of subtle etch features in a calcite crystal surface. The 2 modes yield similar results, but phase-detection opens up the prospect of faster imaging.

  11. Adaptive evolution in ecological communities.

    Directory of Open Access Journals (Sweden)

    Martin M Turcotte

    Full Text Available Understanding how natural selection drives evolution is a key challenge in evolutionary biology. Most studies of adaptation focus on how a single environmental factor, such as increased temperature, affects evolution within a single species. The biological relevance of these experiments is limited because nature is infinitely more complex. Most species are embedded within communities containing many species that interact with one another and the physical environment. To understand the evolutionary significance of such ecological complexity, experiments must test the evolutionary impact of interactions among multiple species during adaptation. Here we highlight an experiment that manipulates species composition and tracks evolutionary responses within each species, while testing for the mechanisms by which species interact and adapt to their environment. We also discuss limitations of previous studies of adaptive evolution and emphasize how an experimental evolution approach can circumvent such shortcomings. Understanding how community composition acts as a selective force will improve our ability to predict how species adapt to natural and human-induced environmental change.

  12. Detection and Attribution of Simulated Climatic Extreme Events and Impacts: High Sensitivity to Bias Correction

    Science.gov (United States)

    Sippel, S.; Otto, F. E. L.; Forkel, M.; Allen, M. R.; Guillod, B. P.; Heimann, M.; Reichstein, M.; Seneviratne, S. I.; Kirsten, T.; Mahecha, M. D.

    2015-12-01

    Understanding, quantifying and attributing the impacts of climatic extreme events and variability is crucial for societal adaptation in a changing climate. However, climate model simulations generated for this purpose typically exhibit pronounced biases in their output that hinders any straightforward assessment of impacts. To overcome this issue, various bias correction strategies are routinely used to alleviate climate model deficiencies most of which have been criticized for physical inconsistency and the non-preservation of the multivariate correlation structure. We assess how biases and their correction affect the quantification and attribution of simulated extremes and variability in i) climatological variables and ii) impacts on ecosystem functioning as simulated by a terrestrial biosphere model. Our study demonstrates that assessments of simulated climatic extreme events and impacts in the terrestrial biosphere are highly sensitive to bias correction schemes with major implications for the detection and attribution of these events. We introduce a novel ensemble-based resampling scheme based on a large regional climate model ensemble generated by the distributed weather@home setup[1], which fully preserves the physical consistency and multivariate correlation structure of the model output. We use extreme value statistics to show that this procedure considerably improves the representation of climatic extremes and variability. Subsequently, biosphere-atmosphere carbon fluxes are simulated using a terrestrial ecosystem model (LPJ-GSI) to further demonstrate the sensitivity of ecosystem impacts to the methodology of bias correcting climate model output. We find that uncertainties arising from bias correction schemes are comparable in magnitude to model structural and parameter uncertainties. The present study consists of a first attempt to alleviate climate model biases in a physically consistent way and demonstrates that this yields improved simulations of

  13. Systematic review of the empirical evidence of study publication bias and outcome reporting bias.

    Directory of Open Access Journals (Sweden)

    Kerry Dwan

    Full Text Available BACKGROUND: The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study publication bias has been recognised as a potential threat to the validity of meta-analysis and can make the readily available evidence unreliable for decision making. Until recently, outcome reporting bias has received less attention. METHODOLOGY/PRINCIPAL FINDINGS: We review and summarise the evidence from a series of cohort studies that have assessed study publication bias and outcome reporting bias in randomised controlled trials. Sixteen studies were eligible of which only two followed the cohort all the way through from protocol approval to information regarding publication of outcomes. Eleven of the studies investigated study publication bias and five investigated outcome reporting bias. Three studies have found that statistically significant outcomes had a higher odds of being fully reported compared to non-significant outcomes (range of odds ratios: 2.2 to 4.7. In comparing trial publications to protocols, we found that 40-62% of studies had at least one primary outcome that was changed, introduced, or omitted. We decided not to undertake meta-analysis due to the differences between studies. CONCLUSIONS: Recent work provides direct empirical evidence for the existence of study publication bias and outcome reporting bias. There is strong evidence of an association between significant results and publication; studies that report positive or significant results are more likely to be published and outcomes that are statistically significant have higher odds of being fully reported. Publications have been found to be inconsistent with their protocols. Researchers need to be aware of the problems of both types of bias and efforts should be concentrated on improving the reporting of trials.

  14. Ocean-atmosphere processes driving Indian summer monsoon biases in CFSv2 hindcasts

    Science.gov (United States)

    Narapusetty, Balachandrudu; Murtugudde, Raghu; Wang, Hui; Kumar, Arun

    2016-09-01

    with warmer SSTs lead to a weakening of Findlater jet and the other in the east equatorial IO where a remote forcing by the predominantly westerly bias in the western-central equatorial IO in the summer strengthen the seasonal downwelling Kelvin wave that in turn deepens the thermocline in the eastern IO. The equatorial Kelvin wave continues as a coastal Kelvin wave and disperses as Rossby waves off Sumatra and induces positive SST and precipitation biases in the eastern and southern Bay of Bengal. This study shows that the biases that first appear in winds lead to a cascade of coupled processes that exacerbate the subsequent biases by modulating the evolution of seasonal processes such as the annual Kelvin and Rossby waves and the cross-equatorial vertically integrated moisture transport. While this analysis does not offer any particular insights into improving the ISM forecasts, it is a foundational first step towards this goal.

  15. Bayesian item selection in constrained adaptive testing using shadow tests

    OpenAIRE

    Bernard P. Veldkamp

    2010-01-01

    Application of Bayesian item selection criteria in computerized adaptive testing might result in improvement of bias and MSE of the ability estimates. The question remains how to apply Bayesian item selection criteria in the context of constrained adaptive testing, where large numbers of specifications have to be taken into account in the item selection process. The Shadow Test Approach is a general purpose algorithm for administering constrained CAT. In this paper it is shown how the approac...

  16. Structured and Unstructured Cache Models for SMT Domain Adaptation

    OpenAIRE

    Louis, Annie; Webber, Bonnie L.

    2014-01-01

    We present a French to English translation system for Wikipedia biography articles. We use training data from out-of-domain corpora and adapt the system for biographies. We propose two forms of domain adaptation. The first biases the system towards words likely in biographies and encourages repetition of words across the document. Since biographies in Wikipedia follow a regular structure, our second model exploits this structure as a sequence of topic segments, where each segment discusses a ...

  17. Is GC bias in the nuclear genome of the carnivorous plant Utricularia driven by ROS-based mutation and biased gene conversion?

    Science.gov (United States)

    Ibarra-Laclette, Enrique; Albert, Victor A; Herrera-Estrella, Alfredo; Herrera-Estrella, Luis

    2011-11-01

    At less than 90 Mbp, the tiny nuclear genome of the carnivorous bladderwort plant Utricularia is an attractive model system for studying molecular evolutionary processes leading to genome miniaturization. Recently, we reported that expression of genes encoding DNA repair and reactive oxygen species (ROS) detoxification enzymes is highest in Utricularia traps, and we argued that ROS mutagenic action correlates with the high nucleotide substitution rates observed in the Utricularia plastid, mitochondrial, and nuclear genomes. Here, we extend our analysis of 100 nuclear genes from Utricularia and related asterid eudicots to examine nucleotide substitution biases and their potential correlation with ROS-induced DNA lesions. We discovered an unusual bias toward GC nucleotides, most prominently in transition substitutions at the third position of codons, which are presumably silent with respect to adaptation. Given the general tendency of biased gene conversion to drive GC bias, and of ROS to induce double strand breaks requiring recombinational repair, we propose that some of the unusual features of the bladderwort and its genome may be more reflective of these nonadaptive processes than of natural selection. PMID:22057327

  18. Malaysia and forced migration

    Directory of Open Access Journals (Sweden)

    Arzura Idris

    2012-06-01

    Full Text Available This paper analyzes the phenomenon of “forced migration” in Malaysia. It examines the nature of forced migration, the challenges faced by Malaysia, the policy responses and their impact on the country and upon the forced migrants. It considers forced migration as an event hosting multifaceted issues related and relevant to forced migrants and suggests that Malaysia has been preoccupied with the issue of forced migration movements. This is largely seen in various responses invoked from Malaysia due to “south-south forced migration movements.” These responses are, however, inadequate in terms of commitment to the international refugee regime. While Malaysia did respond to economic and migration challenges, the paper asserts that such efforts are futile if she ignores issues critical to forced migrants.

  19. Developing Personalized Sensorimotor Adaptability Countermeasures for Spaceflight

    Science.gov (United States)

    Mulavara, A. P.; Seidler, R. D.; Peters, B.; Cohen, H. S.; Wood, S.; Bloomberg, J. J.

    2016-01-01

    Astronauts experience sensorimotor disturbances during their initial exposure to microgravity and during the re-adaptation phase following a return to an Earth-gravitational environment. Interestingly, astronauts who return from spaceflight show substantial differences in their abilities to readapt to a gravitational environment. The ability to predict the manner and degree to which individual astronauts would be affected would improve the effectiveness of countermeasure training programs designed to enhance sensorimotor adaptability. In this paper we will be presenting results from our ground-based study that show how behavioral, brain imaging and genomic data may be used to predict individual differences in sensorimotor adaptability to novel sensorimotor environments. This approach will allow us to better design and implement sensorimotor adaptability training countermeasures against decrements in post-mission adaptive capability that are customized for each crewmember's sensory biases, adaptive capacity, brain structure, functional capacities, and genetic predispositions. The ability to customize adaptability training will allow more efficient use of crew time during training and will optimize training prescriptions for astronauts to ensure expected outcomes.

  20. Traders, Courts and the Home Bias Puzzle

    OpenAIRE

    Turrini, Alessandro; Van Ypersele, Tanguy

    2001-01-01

    Recent evidence shows that the ‘home bias puzzle’ in international trade may be associated with the mere presence of national borders (McCallum (1995)). In this Paper we provide a theoretical framework to explain why borders may matter so much for trade. Our argument is that even between perfectly integrated and similar countries the legal system differs, so that legal costs are higher when business is done abroad. Using a matching model of trade, we show that the home bias is associated with...

  1. Optimal design of APD biasing circuit

    Institute of Scientific and Technical Information of China (English)

    SUN Chun-sheng; QIN Shi-qiao; WANG Xing-shu; ZHU Dong-hua

    2007-01-01

    This paper proposes a control method for avalanche photodiode (APD) reverse bias with temperature compensation and load resistance compensation. The influence of background light and load resistance on APD detection circuit is analyzed in detail. A theoretical model of temperature compensation and load resistance compensation is established, which is used for APD biasing circuit designing. It is predicted that this control method is especially suitable for LD laser range finder used on vehicles. Experimental results confirm thatthe design proposed in this paper can considerablely improve the performance of range finder.

  2. Terahertz Bloch oscillator with a modulated bias.

    Science.gov (United States)

    Hyart, Timo; Alexeeva, Natalia V; Mattas, Jussi; Alekseev, Kirill N

    2009-04-10

    Electrons performing Bloch oscillations in an energy band of a dc-biased superlattice in the presence of weak dissipation can potentially generate THz fields at room temperature. The realization of such a Bloch oscillator is a long-standing problem due to the instability of a homogeneous electric field in conditions of negative differential conductivity. We establish the theoretical feasibility of stable THz gain in a long superlattice device in which the bias is quasistatically modulated by microwave fields. The modulation waveforms must have at least two harmonics in their spectra.

  3. BIAS GENDER: MASALAH UTAMA DALAM INTERPRETASI ARKEOLOGI

    Directory of Open Access Journals (Sweden)

    Mimi Savitri

    2007-06-01

    Full Text Available Gender bias is an important theme in Gender Archaeology. It is influenced by modern people thinking and it has influenced archaeological interpretation for a long time. As a result, archaeological interpretation of past society is not objective. This problem should be solved to reach an objective interpretation of people’s life in the past. The author argues that gender bias in archaeology can be solved by actively criticizing androcentrism and paying more attention to men and women’s relationship in the past.

  4. Recursive bias estimation and L2 boosting

    Energy Technology Data Exchange (ETDEWEB)

    Hengartner, Nicolas W [Los Alamos National Laboratory; Cornillon, Pierre - Andre [INRA, FRANCE; Matzner - Lober, Eric [RENNE, FRANCE

    2009-01-01

    This paper presents a general iterative bias correction procedure for regression smoothers. This bias reduction schema is shown to correspond operationally to the L{sub 2} Boosting algorithm and provides a new statistical interpretation for L{sub 2} Boosting. We analyze the behavior of the Boosting algorithm applied to common smoothers S which we show depend on the spectrum of I - S. We present examples of common smoother for which Boosting generates a divergent sequence. The statistical interpretation suggest combining algorithm with an appropriate stopping rule for the iterative procedure. Finally we illustrate the practical finite sample performances of the iterative smoother via a simulation study.

  5. Hydrophobic Forces in Flotation

    OpenAIRE

    Pazhianur, Rajesh R

    1999-01-01

    An atomic force microscope (AFM) has been used to conduct force measurements to better understand the role of hydrophobic forces in flotation. The force measurements were conducted between a flat mineral substrate and a hydrophobic glass sphere in aqueous solutions. It is assumed that the hydrophobic glass sphere may simulate the behavior of air bubbles during flotation. The results may provide information relevant to the bubble-particle interactions occurring during flotation. The glass ...

  6. Galaxy Bias and its Effects on the Baryon Acoustic Oscillations Measurements

    CERN Document Server

    Mehta, Kushal T; Eckel, Jonathan; Eisenstein, Daniel J; Metchnik, Marc; Pinto, Philip; Xu, Xiaoying

    2011-01-01

    The baryon acoustic oscillation (BAO) feature in the clustering of matter in the universe serves as a robust standard ruler and hence can be used to map the expansion history of the universe. We use high force resolution simulations to analyze the effects of galaxy bias on the measurements of the BAO signal. We apply a variety of Halo Occupation Distributions (HODs) and produce biased mass tracers to mimic different galaxy populations. We investigate whether galaxy bias changes the non-linear shifts on the acoustic scale relative to the underlying dark matter distribution presented by Seo et al (2009). For the less biased HOD models (b 3) show a shift at moderate significance (0.79% \\pm 0.31% for the most extreme case). We test the one-step reconstruction technique introduced by Eisenstein et al. (2007) in the case of realistic galaxy bias and shot noise. The reconstruction scheme increases the correlation between the initial and final (z = 1) density fields achieving an equivalent level of correlation at ne...

  7. Influence of substrate bias voltage on the microstructure of nc-SiOx:H film

    Institute of Scientific and Technical Information of China (English)

    李慧敏; 于威; 徐艳梅; 季云; 蒋昭毅; 王新占; 李晓苇; 傅广生

    2015-01-01

    Amorphous silicon oxide containing nanocrystalline silicon grain (nc-SiOx:H) films are prepared by plasma-enhanced chemical vapor deposition technique at different negative substrate bias voltages. The influence of bias voltage applied to substrate on the microstructure is investigated. The analysis of x-ray diffraction spectra evidences the in-situ growth of nanocrystalline Si. The grain size can be well controlled by varying the substrate bias voltage, and the largest size is obtained at 60 V. Fourier transform infrared spectra studies on the microstructure evolutions of the nc-SiOx:H films suggest that the absorption peak intensities which are related to the defect densities can be well controlled. It can be attributed to the fact that the negative bias voltage provides a useful way to change the energies of the particles in the deposition process, which can provide sufficient driving force for the diffusion and movement for the species on the growing surface and effectively passivate the dangling bonds. Also the larger grain size and lower band gap which will result in better photosensitivity can also be obtained with a moderate substrate bias voltage of 60 V.

  8. On System-Dependent Sources of Uncertainty and Bias in Ultrasonic Quantitative Shear-Wave Imaging.

    Science.gov (United States)

    Deng, Yufeng; Rouze, Ned C; Palmeri, Mark L; Nightingale, Kathryn R

    2016-03-01

    Ultrasonic quantitative shear-wave imaging methods have been developed over the last decade to estimate tissue elasticity by measuring the speed of propagating shear waves following acoustic radiation force excitation. This work discusses eight sources of uncertainty and bias arising from ultrasound system-dependent parameters in ultrasound shear-wave speed (SWS) measurements. Each of the eight sources of error is discussed in the context of a linear, isotropic, elastic, homogeneous medium, combining previously reported analyses with Field II simulations, full-wave 2-D acoustic propagation simulations, and experimental studies. Errors arising from both spatial and temporal sources lead to errors in SWS measurements. Arrival time estimation noise, speckle bias, hardware fluctuations, and phase aberration cause uncertainties (variance) in SWS measurements, while pulse repetition frequency (PRF) and beamforming errors, as well as coupling medium sound speed mismatch, cause biases in SWS measurements (accuracy errors). Calibration of the sources of bias is an important step in the development of shear-wave imaging systems. In a well-calibrated system, where the sources of bias are minimized, and averaging over a region of interest (ROI) is employed to reduce the sources of uncertainty, an SWS error can be expected. PMID:26886980

  9. Structural tuning of nanogaps using electromigration induced by field emission current with bipolar biasing

    Energy Technology Data Exchange (ETDEWEB)

    Yagi, Mamiko; Ito, Mitsuki; Shirakashi, Jun-ichi, E-mail: shrakash@cc.tuat.ac.jp [Department of Electrical and Electronic Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588 (Japan)

    2015-07-07

    We report a new method for fabrication of Ni nanogaps based on electromigration induced by a field emission current. This method is called “activation” and is demonstrated here using a current source with alternately reversing polarities. The activation procedure with alternating current bias, in which the current source polarity alternates between positive and negative bias conditions, is performed with planar Ni nanogaps defined on SiO{sub 2}/Si substrates at room temperature. During negative biasing, a Fowler-Nordheim field emission current flows from the source (cathode) to the drain (anode) electrode. The Ni atoms at the tip of the drain electrode are thus activated and then migrate across the gap from the drain to the source electrode. In contrast, in the positive bias case, the field emission current moves the activated atoms from the source to the drain electrode. These two procedures are repeated until the tunnel resistance of the nanogaps is successively reduced from 100 TΩ to 48 kΩ. Scanning electron microscopy and atomic force microscopy studies showed that the gap separation narrowed from approximately 95 nm to less than 10 nm because of the Ni atoms that accumulated at the tips of both the source and drain electrodes. These results show that the alternately biased activation process, which is a newly proposed atom transfer technique, can successfully control the tunnel resistance of the Ni nanogaps and is a suitable method for formation of ultrasmall nanogap structures.

  10. Galaxy bias and its effects on the Baryon acoustic oscillations measurements

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, Kushal T. [Univ. of Arizona, Tucson, AZ (United States); Seo, Hee -Jong [Univ. of California, Berkeley, CA (United States); Fermi National Accelerator Lab., Batavia, IL (United States); Eckel, Jonathan [Univ. of Arizona, Tucson, AZ (United States); Eisenstein, Daniel J. [Univ. of Arizona, Tucson, AZ (United States); Harvard Univ., Cambridge, MA (United States); Metchnik, Marc [Univ. of Arizona, Tucson, AZ (United States); Pinto, Philip [Univ. of Arizona, Tucson, AZ (United States); Xu, Xiaoying [Univ. of Arizona, Tucson, AZ (United States)

    2011-05-31

    The baryon acoustic oscillation (BAO) feature in the clustering of matter in the universe serves as a robust standard ruler and hence can be used to map the expansion history of the universe. We use high force resolution simulations to analyze the effects of galaxy bias on the measurements of the BAO signal. We apply a variety of Halo Occupation Distributions (HODs) and produce biased mass tracers to mimic different galaxy populations. We investigate whether galaxy bias changes the non-linear shifts on the acoustic scale relative to the underlying dark matter distribution presented by Seo et al. (2009). For the less biased HOD models (b < 3), we do not detect any shift in the acoustic scale relative to the no-bias case, typically 0.10% ± 0.10%. However, the most biased HOD models (b > 3) show a shift at moderate significance (0.79% ± 0.31% for the most extreme case). We test the one-step reconstruction technique introduced by Eisenstein et al. (2007) in the case of realistic galaxy bias and shot noise. The reconstruction scheme increases the correlation between the initial and final (z = 1) density fields achieving an equivalent level of correlation at nearly twice the wavenumber after reconstruction. Reconstruction reduces the shifts and errors on the shifts. We find that after reconstruction the shifts from the galaxy cases and the dark matter case are consistent with each other and with no shift. The 1σ systematic errors on the distance measurements inferred from our BAO measurements with various HODs after reconstruction are about 0.07%-0.15%.

  11. Another analytic view about quantifying social forces

    CERN Document Server

    Ausloos, Marcel

    2012-01-01

    Montroll had considered a Verhulst evolution approach for introducing a notion he called "social force", to describe a jump in some economic output when a new technology or product outcompetes a previous one. In fact, Montroll's adaptation of Verhulst equation is more like an economic field description than a "social force". The empirical Verhulst logistic function and the Gompertz double exponential law are used here in order to present an alternative view, within a similar mechanistic physics framework. As an example, a "social force" modifying the rate in the number of temples constructed by a religious movement, the Antoinist community, between 1910 and 1940 in Belgium is found and quantified. Practically, two temple inauguration regimes are seen to exist over different time spans, separated by a gap attributed to a specific "constraint", a taxation system, but allowing for a different, smooth, evolution rather than a jump. The impulse force duration is also emphasized as being better taken into account w...

  12. Development of Integrated ASR Model Forcing Data and Their Applications to Improve CAM

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Minghua [Research Foundation of the State University of New York, Albany, NY (United States)

    2016-01-01

    In this project, we have (1) improved the constrained variational analysis algorithm of ARM model forcing data, and (2) used the ARM forcing data to identify systematic biases in clouds and radiation in the CAM5 and design new physical parameterizations to improve it.

  13. Debunking Coriolis Force Myths

    Science.gov (United States)

    Shakur, Asif

    2014-01-01

    Much has been written and debated about the Coriolis force. Unfortunately, this has done little to demystify the paradoxes surrounding this fictitious force invoked by an observer in a rotating frame of reference. It is the purpose of this article to make another valiant attempt to slay the dragon of the Coriolis force! This will be done without…

  14. Crossflow force transducer

    International Nuclear Information System (INIS)

    A force transducer for measuring lift and drag coefficients for a circular cylinder in turbulent water flow is presented. In addition to describing the actual design and construction of the strain-gauged force- ring based transducer, requirements for obtained valid fluid force test data are discussed, and pertinent flow test experience is related

  15. Adaptive Feedback Cancellation With Band-Limited LPC Vocoder in Digital Hearing Aids

    DEFF Research Database (Denmark)

    Ma, Guilin; Gran, Fredrik; Jacobsen, Finn;

    2011-01-01

    Feedback oscillation is one of the major issues with hearing aids. An effective way of feedback suppression is adaptive feedback cancellation, which uses an adaptive filter to estimate the feedback path. However, when the external input signal is correlated with the receiver input signal......, the estimate of the feedback path is biased. This so-called “bias problem” results in a large modeling error and a cancellation of the desired signal. This paper proposes a band-limited linear predictive coding based approach to reduce the bias. The idea is to replace the hearing-aid output with a synthesized...

  16. Attention Bias Variability and Symptoms of Posttraumatic Stress Disorder

    OpenAIRE

    Iacoviello, Brian M.; Wu, Gang; Abend, Rany; Murrough, James W.; Feder, Adriana; Fruchter, Eyal; Levinstein, Yoav; Wald, Ilan; Bailey, Christopher R.; Pine, Daniel S.; Neumeister, Alexander; Bar-Haim, Yair; Charney, Dennis S.

    2014-01-01

    Cognitive theories implicate information-processing biases in the etiology of anxiety disorders. Results of attention-bias studies in posttraumatic stress disorder (PTSD) have been inconsistent, suggesting biases towards and away from threat. Within-subject variability of attention biases in posttraumatic patients may be a useful marker for attentional control impairment and the development of posttrauma symptoms. This study reports 2 experiments investigating threat-related attention biases,...

  17. The influence of cognitive biases on psychophysiological vulnerability to stress

    OpenAIRE

    Randall, Kate

    2012-01-01

    Individuals who disproportionately attend to negative aspects of a situation (attention bias), or who unduly interpret ambiguity in a negative manner (interpretive bias) report more psychological ill-effects of stress than those with balanced or positively-skewed inclinations. Cognitive Bias Modification (CBM) techniques improve maladaptive biases through implicitly-based association learning, with induced positive biases buffering the future perception of stress. Six experimen...

  18. Phase-field modeling of dendritic growth under forced flow based on adaptive finite element method%基于自适应有限元相场模型模拟强制流动条件下的枝晶生长

    Institute of Scientific and Technical Information of China (English)

    朱昶胜; 雷鹏; 肖荣振; 冯力

    2015-01-01

    A mathematical model combined projection algorithm with phase-field method was applied. The adaptive finite element method was adopted to solve the model based on the non-uniform grid, and the behavior of dendritic growth was simulated from undercooled nickel melt under the forced flow. The simulation results show that the asymmetry behavior of the dendritic growth is caused by the forced flow. When the flow velocity is less than the critical value, the asymmetry of dendrite is little influenced by the forced flow. Once the flow velocity reaches or exceeds the critical value, the controlling factor of dendrite growth gradually changes from thermal diffusion to convection. With the increase of the flow velocity, the deflection angle towards upstream direction of the primary dendrite stem becomes larger. The effect of the dendrite growth on the flow field of the melt is apparent. With the increase of the dendrite size, the vortex is present in the downstream regions, and the vortex region is gradually enlarged. Dendrite tips appear to remelt. In addition, the adaptive finite element method can reduce CPU running time by one order of magnitude compared with uniform grid method, and the speed-up ratio is proportional to the size of computational domain.%应用投影算法与相场法相结合的数学模型,采用基于非均匀网格的自适应有限元法求解该模型,并对强制流动作用下镍过冷熔体中枝晶生长行为进行模拟。模拟结果表明,强迫对流的引入导致枝晶生长的不对称性。当流速小于临界值时,流动对枝晶的不对称生长影响较小;当流速达到或超过临界值时,枝晶生长的控制因素逐渐从热扩散过渡到对流。随着流速的增大,流动法向的一次枝晶臂朝逆流方向倾斜角度增大。而枝晶生长对熔体流动具有明显的影响。随着枝晶尺寸的增大,在顺流区域产生涡流效应,涡流区逐渐扩大并在枝晶尖端出现重熔现

  19. Leadership Adaptation and Traits in Nepalese Police Forces

    OpenAIRE

    Thakur Mohan Shrestha

    2015-01-01

    Recently, the role of leadership has been considered as one of the crucial factors for the success of any organization. However, what constitutes the effective leaders and what is the status of leaderships is still a subject of study. Hence, this research article is carried out with a mixed method. Based on the evaluation of 7 leadership styles, Bass and Avolio (1994)'s "5Is" behaviors, 49 traits, and 28 affecting elements for the development of police officers in Nepal, this study has used a...

  20. Biased Brownian motion in narrow channels with asymmetry and anisotropy

    Science.gov (United States)

    Peng, Zheng; To, Kiwing

    2016-08-01

    We study Brownian motion of a single millimeter size bead confined in a quasi-two-dimensional horizontal channel with built-in anisotropy and asymmetry. Channel asymmetry is implemented by ratchet walls while anisotropy is introduced using a channel base that is grooved along the channel axis so that a bead can acquire a horizontal impulse perpendicular to the longitudinal direction when it collides with the base. When energy is injected to the channel by vertical vibration, the combination of asymmetric walls and anisotropic base induces an effective force which drives the bead into biased diffusive motion along the channel axis with diffusivity and drift velocity increase with vibration strength. The magnitude of this driving force, which can be measured in experiments on a tilted channel, is found to be consistent with those obtained from dynamic mobility and position probability distribution measurements. These results are explained by a simple collision model that suggests the random kinetic energy transfer between different translational degrees of freedom may be turned into useful work in the presence of asymmetry and anisotropy.

  1. Cognitive bias measurement and social anxiety disorder: Correlating self-report data and attentional bias

    Directory of Open Access Journals (Sweden)

    Alexander Miloff

    2015-09-01

    Full Text Available Social anxiety disorder (SAD and attentional bias are theoretically connected in cognitive behavioral therapeutic models. In fact, there is an emerging field focusing on modifying attentional bias as a stand-alone treatment. However, it is unclear to what degree these attentional biases are present before commencing treatment. The purpose of this study was to measure pre-treatment attentional bias in 153 participants diagnosed with SAD using a home-based Internet version of the dot-probe paradigm. Results showed no significant correlation for attentional bias (towards or away from negative words or faces and the self-rated version of the Liebowitz Social Anxiety Scale (LSAS-SR. However, two positive correlations were found for the secondary measures Generalized Anxiety Disorder 7 (GAD-7 and Patient Health Questionnaire 9 (PHQ-9. These indicated that those with elevated levels of anxiety and depression had a higher bias towards negative faces in neutral–negative and positive–negative valence combinations, respectively. The unreliability of the dot-probe paradigm and home-based Internet delivery are discussed to explain the lack of correlations between LSAS-SR and attentional bias. Changes to the dot-probe task are suggested that could improve reliability.

  2. Obtaining the correct sea surface temperature: bias correction of regional climate model data for the Mediterranean Sea

    Science.gov (United States)

    Macias, Diego; Garcia-Gorriz, Elisa; Dosio, Alessandro; Stips, Adolf; Keuler, Klaus

    2016-02-01

    Here, the COSMO Climate Limited-area Modelling (CCLM) regional climate model (RCM) is used as external forcing for a Mediterranean basin-scale ocean model based on the general estuarine transport model (GETM). CCLM is forced by different global climate models (GCMs) (MPI and EcEarth) and by the ERA-interim (ERAin) reanalysis. Sea surface temperatures (SST) simulated by the different runs of the ocean model are compared with satellite measurements. As a substantial cold bias in simulated SST is found, a simple bias-correction methodology is applied to the RCM atmospheric variables, namely (1) air temperature (which is usually underestimated for the region by RCMs runs), (2) cloud cover (typically overestimated) and (3) wind intensity (as zonal wind intensity is usually overestimated). The performed analysis identifies wind velocity as the most important variable to correct in order to satisfactorily obtain Mediterranean SST. For many of the RCM realizations significant improvement in the simulated SST are only achieved when wind intensity values were bias-corrected towards observed values. Air temperature and cloud cover had a more marginal importance in reducing the SST bias observed in RCM-forced runs of the ocean model. By comparing the ERAin-driven run and the GCMs driven runs, our analyses suggest that the main source of observed bias is related with the GCMs being used as lateral boundary condition for the RCM realizations. However, a relative simple bias-correction methodology is sufficient to reduce a large part of the induced bias in SST and to improve the vertical water stratification characteristics within the Mediterranean basin that will allow to analyze current and future biogeochemical conditions of the studied basin.

  3. Efficacy of climate forcings

    Science.gov (United States)

    Hansen, J.; Sato, M.; Ruedy, R.; Nazarenko, L.; Lacis, A.; Schmidt, G. A.; Russell, G.; Aleinov, I.; Bauer, M.; Bauer, S.; Bell, N.; Cairns, B.; Canuto, V.; Chandler, M.; Cheng, Y.; Del Genio, A.; Faluvegi, G.; Fleming, E.; Friend, A.; Hall, T.; Jackman, C.; Kelley, M.; Kiang, N.; Koch, D.; Lean, J.; Lerner, J.; Lo, K.; Menon, S.; Miller, R.; Minnis, P.; Novakov, T.; Oinas, V.; Perlwitz, Ja.; Perlwitz, Ju.; Rind, D.; Romanou, A.; Shindell, D.; Stone, P.; Sun, S.; Tausnev, N.; Thresher, D.; Wielicki, B.; Wong, T.; Yao, M.; Zhang, S.

    2005-09-01

    We use a global climate model to compare the effectiveness of many climate forcing agents for producing climate change. We find a substantial range in the "efficacy" of different forcings, where the efficacy is the global temperature response per unit forcing relative to the response to CO2 forcing. Anthropogenic CH4 has efficacy ˜110%, which increases to ˜145% when its indirect effects on stratospheric H2O and tropospheric O3 are included, yielding an effective climate forcing of ˜0.8 W/m2 for the period 1750-2000 and making CH4 the largest anthropogenic climate forcing other than CO2. Black carbon (BC) aerosols from biomass burning have a calculated efficacy ˜58%, while fossil fuel BC has an efficacy ˜78%. Accounting for forcing efficacies and for indirect effects via snow albedo and cloud changes, we find that fossil fuel soot, defined as BC + OC (organic carbon), has a net positive forcing while biomass burning BC + OC has a negative forcing. We show that replacement of the traditional instantaneous and adjusted forcings, Fi and Fa, with an easily computed alternative, Fs, yields a better predictor of climate change, i.e., its efficacies are closer to unity. Fs is inferred from flux and temperature changes in a fixed-ocean model run. There is remarkable congruence in the spatial distribution of climate change, normalized to the same forcing Fs, for most climate forcing agents, suggesting that the global forcing has more relevance to regional climate change than may have been anticipated. Increasing greenhouse gases intensify the Hadley circulation in our model, increasing rainfall in the Intertropical Convergence Zone (ITCZ), Eastern United States, and East Asia, while intensifying dry conditions in the subtropics including the Southwest United States, the Mediterranean region, the Middle East, and an expanding Sahel. These features survive in model simulations that use all estimated forcings for the period 1880-2000. Responses to localized forcings, such

  4. Adaptively robust filtering with classified adaptive factors

    Institute of Scientific and Technical Information of China (English)

    CUI Xianqiang; YANG Yuanxi

    2006-01-01

    The key problems in applying the adaptively robust filtering to navigation are to establish an equivalent weight matrix for the measurements and a suitable adaptive factor for balancing the contributions of the measurements and the predicted state information to the state parameter estimates. In this paper, an adaptively robust filtering with classified adaptive factors was proposed, based on the principles of the adaptively robust filtering and bi-factor robust estimation for correlated observations. According to the constant velocity model of Kalman filtering, the state parameter vector was divided into two groups, namely position and velocity. The estimator of the adaptively robust filtering with classified adaptive factors was derived, and the calculation expressions of the classified adaptive factors were presented. Test results show that the adaptively robust filtering with classified adaptive factors is not only robust in controlling the measurement outliers and the kinematic state disturbing but also reasonable in balancing the contributions of the predicted position and velocity, respectively, and its filtering accuracy is superior to the adaptively robust filter with single adaptive factor based on the discrepancy of the predicted position or the predicted velocity.

  5. Bias in emerging biomarkers for bipolar disorder

    DEFF Research Database (Denmark)

    Carvalho, A F; Köhler, C A; Fernandes, B S;

    2016-01-01

    BACKGROUND: To date no comprehensive evaluation has appraised the likelihood of bias or the strength of the evidence of peripheral biomarkers for bipolar disorder (BD). Here we performed an umbrella review of meta-analyses of peripheral non-genetic biomarkers for BD. METHOD: The Pubmed...

  6. Exchange bias mediated by interfacial nanoparticles (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Berkowitz, A. E., E-mail: aberk@ucsd.edu [Department of Physics, University of California, San Diego, La Jolla, California 92093 (United States); Center for Magnetic Recording Research, University of California, California 92093 (United States); Sinha, S. K. [Department of Physics, University of California, San Diego, La Jolla, California 92093 (United States); Fullerton, E. E. [Center for Magnetic Recording Research, University of California, California 92093 (United States); Smith, D. J. [Department of Physics, Arizona State University, Tempe, Arizona 85287 (United States)

    2015-05-07

    The objective of this study on the iconic exchange-bias bilayer Permalloy/CoO has been to identify those elements of the interfacial microstructure and accompanying magnetic properties that are responsible for the exchange-bias and hysteretic properties of this bilayer. Both epitaxial and polycrystalline samples were examined. X-ray and neutron reflectometry established that there existed an interfacial region, of width ∼1 nm, whose magnetic properties differed from those of Py or CoO. A model was developed for the interfacial microstructure that predicts all the relevant properties of this system; namely; the temperature and Permalloy thickness dependence of the exchange-bias, H{sub EX}, and coercivity, H{sub C}; the much smaller measured values of H{sub EX} from what was nominally expected; the different behavior of H{sub EX} and H{sub C} in epitaxial and polycrystalline bilayers. A surprising result is that the exchange-bias does not involve direct exchange-coupling between Permalloy and CoO, but rather is mediated by CoFe{sub 2}O{sub 4} nanoparticles in the interfacial region.

  7. Jackknife bias reduction for polychotomous logistic regression.

    Science.gov (United States)

    Bull, S B; Greenwood, C M; Hauck, W W

    1997-03-15

    Despite theoretical and empirical evidence that the usual MLEs can be misleading in finite samples and some evidence that bias reduced estimates are less biased and more efficient, they have not seen a wide application in practice. One can obtain bias reduced estimates by jackknife methods, with or without full iteration, or by use of higher order terms in a Taylor series expansion of the log-likelihood to approximate asymptotic bias. We provide details of these methods for polychotomous logistic regression with a nominal categorical response. We conducted a Monte Carlo comparison of the jackknife and Taylor series estimates in moderate sample sizes in a general logistic regression setting, to investigate dichotomous and trichotomous responses and a mixture of correlated and uncorrelated binary and normal covariates. We found an approximate two-step jackknife and the Taylor series methods useful when the ratio of the number of observations to the number of parameters is greater than 15, but we cannot recommend the two-step and the fully iterated jackknife estimates when this ratio is less than 20, especially when there are large effects, binary covariates, or multicollinearity in the covariates.

  8. Knowledge of Social Affiliations Biases Economic Decisions

    Science.gov (United States)

    Martinez, Joel E.; Mack, Michael L.; Gelman, Bernard D.; Preston, Alison R.

    2016-01-01

    An individual’s reputation and group membership can produce automatic judgments and behaviors toward that individual. Whether an individual’s social reputation impacts interactions with affiliates has yet to be demonstrated. We tested the hypothesis that during initial encounters with others, existing knowledge of their social network guides behavior toward them. Participants learned reputations (cooperate, defect, or equal mix) for virtual players through an iterated economic game (EG). Then, participants learned one novel friend for each player. The critical question was how participants treated the friends in a single-shot EG after the friend-learning phase. Participants tended to cooperate with friends of cooperators and defect on friends of defectors, indicative of a decision making bias based on memory for social affiliations. Interestingly, participants’ explicit predictions of the friends’ future behavior showed no such bias. Moreover, the bias to defect on friends of defectors was enhanced when affiliations were learned in a social context; participants who learned to associate novel faces with player faces during reinforcement learning did not show reputation-based bias for associates of defectors during single-shot EG. These data indicate that when faced with risky social decisions, memories of social connections influence behavior implicitly. PMID:27441563

  9. Vowel bias in Danish word-learning

    DEFF Research Database (Denmark)

    Højen, Anders; Nazzi, Thierry

    2016-01-01

    The present study explored whether the phonological bias favoring consonants found in French-learning infants and children when learning new words (Havy & Nazzi, 2009; Nazzi, 2005) is language-general, as proposed by Nespor, Peña and Mehler (2003), or varies across languages, perhaps as a function...

  10. Researching Sex Bias in the Classroom.

    Science.gov (United States)

    Donlan, Dan

    This paper outlines five methods of research on sex bias in the classroom: one-time survey, one class/one treatment, two class/two treatment, one class/random assignment to treatment, and analysis of differentiated effect. It shows how each method could be used in attempting to measure the effect of a unit on Norma Klein's "Mom, the Wolfman and…

  11. Bias sensitive multispectral structures for imaging applications

    International Nuclear Information System (INIS)

    In this paper we present results on the optimization of an pinpii'n' type a-Si:H based three color detector with voltage controlled spectral sensitivity. The sensor element was fabricated on a glass covered with Indium Tin Oxide (ITO) and consists of a p-i-n a-SiC:H multilayer structure which faces the incident illumination, followed by a-SiC:H(-p)/a-SiC:H(-i)/a-Si:H(-i')/a-SiC:H(-n')/ITO heterostructure, that allows the optically addressed readout. Results show that this approach leads to regionally different collection parameters resulting in multispectral photodiodes. In the polychromatic operation mode different sensitivity ranges are programmed by switching between different biases so that the basic colors can be resolved with a single device. Positive bias is needed under blue irradiation and moderated reverse bias under green. The threshold voltage between green and red sensitivity depends on the thickness of the bottom a-SiC:H (-i) layer, and corresponds to the complete confinement of the absorbed green photons across the pinpi sequence. As the thickness of the a-Si:H i'-layer increases, the self-reverse effect due to the front absorption will be balanced by the decrease of the self-forward effect due to the back absorption shifting the threshold voltage to lower reverse bias. The various design parameters are discussed and supported by a 2D numerical simulation

  12. Avoiding bias in safety testing design

    DEFF Research Database (Denmark)

    Calow, Peter

    2011-01-01

    All scientists are biased, no matter what their backgrounds or affiliations, so what is it about the scientific method that overcomes this and which makes science so successful? Key features are transparency and critical peer scrutiny. These general issues will be will be considered in terms...

  13. Very Massive Tracers and Higher Derivative Biases

    CERN Document Server

    Fujita, Tomohiro; Senatore, Leonardo; Vlah, Zvonimir; Angulo, Raul

    2016-01-01

    Most of the upcoming cosmological information will come from analyzing the clustering of the Large Scale Structures (LSS) of the universe through LSS or CMB observations. It is therefore essential to be able to understand their behavior with exquisite precision. The Effective Field Theory of Large Scale Structures (EFTofLSS) provides a consistent framework to make predictions for LSS observables in the mildly non-linear regime. In this paper we focus on biased tracers. We argue that in calculations at a given order in the dark matter perturbations, highly biased tracers will underperform because of their larger higher derivative biases. A natural prediction of the EFTofLSS is therefore that by simply adding higher derivative biases, all tracers should perform comparably well. We implement this prediction for the halo-halo and the halo-matter power spectra at one loop, and the halo-halo-halo, halo-halo-matter, and halo-matter-matter bispectra at tree-level, and compare with simulations. We find good agreement ...

  14. Uncovering Racial Bias in Nursing Fundamentals Textbooks.

    Science.gov (United States)

    Byrne, Michelle M.

    2001-01-01

    The portrayal of African Americans in nursing fundamentals textbooks was analyzed, resulting in 11 themes in the areas of history, culture, and physical assessment. Few African American leaders were included, and racial bias and stereotyping were apparent. Differences were often discussed using Eurocentric norms, and language tended to minimize…

  15. Attentional bias temporal dynamics in remitted depression.

    Science.gov (United States)

    Zvielli, Ariel; Vrijsen, Janna N; Koster, Ernst H W; Bernstein, Amit

    2016-08-01

    Theory implicates attentional bias (AB) or dysregulated attentional processing of emotional information in the recurrence of major depressive episodes. However, empirical study of AB among remitted depressed patients is limited in scope and has yielded mixed findings. Mixed findings may be accounted for by how the field has conceptualized and thereby studied AB. We propose that a novel temporal dynamic process perspective on AB may help disambiguate extant findings and elucidate the nature of AB in remitted depression. Thus, we reexamined Dot Probe data among remitted depressed patients (RMD; n = 328) and nondepressed controls (NDC; n = 82) that previously yielded null effects when AB was quantified by means of the traditional aggregated mean bias score (Vrijsen et al., 2014). We reanalyzed data using a novel computational approach that extracts a series of bias estimations from trial to trial (Zvielli, Bernstein, & Koster, 2015). Key features of these dynamic process signals revealed moderate to excellent reliability relative to the traditional aggregated mean bias scores. These features of AB dynamics-specifically temporal variability in AB including AB toward and away from emotional stimuli-were significantly elevated among RMDs relative to NDCs. Moreover, among RMDs, a greater number of past depressive episodes were associated with elevation in these features of AB dynamics. Effects were not accounted for by residual depressive symptoms or social anxiety symptoms. Findings indicate that dysregulation in attentional processing of emotional information reflected in AB dynamics may be key to depression vulnerability. (PsycINFO Database Record PMID:27505407

  16. Bias and Obfuscation in Kendler's (2005) "Clarification"

    Science.gov (United States)

    Schneider, Kirk J.

    2006-01-01

    This paper comments on the article "Psychology and Phenomenology: A Clarification" by H. H. Kendler. In this article, Kendler misrepresented contemporary existential-humanistic psychology and conventional (or natural) scientific psychology. With regard to the former, he presented a confused, unwittingly biased, and all-too-stereotypic picture.…

  17. Bounding the Bias of Contrastive Divergence Learning

    DEFF Research Database (Denmark)

    Fischer, Anja; Igel, Christian

    2011-01-01

    number of variables in the RBM, and the maximum change in energy that can be produced by changing a single variable. The last reflects the dependence on the absolute values of the RBM parameters. The magnitude of the bias is also affected by the distance in variation between the modeled distribution and...

  18. Examining Gender Bias in Studies of Innovation

    OpenAIRE

    Crowden, N.

    2003-01-01

    This paper examines the presence of a gender bias in studies of innovation. Using the Innovation Systems Research Network (ISRN) and its interview guide as a case study, this research project examines how accurately and completely such innovation studies present gender differences in the innovation process.

  19. A new polarization amplitude bias reduction method

    Science.gov (United States)

    Vidal, Matias; Leahy, J. P.; Dickinson, C.

    2016-09-01

    Polarization amplitude estimation is affected by a positive noise bias, particularly important in regions with low signal-to-noise ratio (SNR). We present a new approach to correct for this bias in the case there is additional information about the polarization angle. We develop the `known-angle estimator' that works in the special case when there is an independent and high SNR (≳ 2σ) measurement of the polarization angle. It is derived for the general case where the uncertainties in the Q, U Stokes parameters are not symmetric. This estimator completely corrects for the polarization bias if the polarization angle is perfectly known. In the realistic case, where the angle template has uncertainties, a small residual bias remains, but that is shown to be much smaller that the one left by other classical estimators. We also test our method with more realistic data, using the noise properties of the three lower frequency maps of Wilkinson Microwave Anisotropy Probe. In this case, the known-angle estimator also produces better results than methods that do not include the angle information. This estimator is therefore useful in the case where the polarization angle is expected to be constant over different data sets with different SNR.

  20. Zero bias transformation and asymptotic expansions

    OpenAIRE

    Jiao, Ying

    2012-01-01

    Let W be a sum of independent random variables. We apply the zero bias transformation to deduce recursive asymptotic expansions for $\\mathbb {E}[h(W)]$ in terms of normal expectations, or of Poisson expectations for integer-valued random variables. We also discuss the estimates of remaining errors.

  1. Accounting for discovery bias in genomic prediction

    Science.gov (United States)

    Our objective was to evaluate an approach to mitigating discovery bias in genomic prediction. Accuracy may be improved by placing greater emphasis on regions of the genome expected to be more influential on a trait. Methods emphasizing regions result in a phenomenon known as “discovery bias” if info...

  2. Sociocognitive Biases in the Evaluation Process.

    Science.gov (United States)

    Perloff, Richard M.; And Others

    1980-01-01

    Causes of evaluator bias are: overemphasizing concrete, salient, and retrievable information; reporting only evidence which confirms hypothesis; focusing on stable personality factors, rather than on situation and environment; developing positive perceptions of a program as both an evaluator and a highly involved participant; statistical naivete;…

  3. Assessing Projection Bias in Consumers' Food Preferences.

    Directory of Open Access Journals (Sweden)

    Tiziana de-Magistris

    Full Text Available The aim of this study is to test whether projection bias exists in consumers' purchasing decisions for food products. To achieve our aim, we used a non-hypothetical experiment (i.e., experimental auction, where hungry and non-hungry participants were incentivized to reveal their willingness to pay (WTP. The results confirm the existence of projection bias when consumers made their decisions on food products. In particular, projection bias existed because currently hungry participants were willing to pay a higher price premium for cheeses than satiated ones, both in hungry and satiated future states. Moreover, participants overvalued the food product more when they were delivered in the future hungry condition than in the satiated one. Our study provides clear, quantitative and meaningful evidence of projection bias because our findings are based on economic valuation of food preferences. Indeed, the strength of this study is that findings are expressed in terms of willingness to pay which is an interpretable amount of money.

  4. Bias and variance in continuous EDA

    OpenAIRE

    Teytaud, Fabien; Teytaud, Olivier

    2009-01-01

    Estimation of Distribution Algorithms are based on statistical estimates. We show that when combining classical tools from statistics, namely bias/variance decomposition, reweighting and quasi-randomization, we can strongly improve the convergence rate. All modifications are easy, compliant with most algorithms, and experimentally very efficient in particular in the parallel case (large offsprings).

  5. Audibility and visual biasing in speech perception

    Science.gov (United States)

    Clement, Bart Richard

    Although speech perception has been considered a predominantly auditory phenomenon, large benefits from vision in degraded acoustic conditions suggest integration of audition and vision. More direct evidence of this comes from studies of audiovisual disparity that demonstrate vision can bias and even dominate perception (McGurk & MacDonald, 1976). It has been observed that hearing-impaired listeners demonstrate more visual biasing than normally hearing listeners (Walden et al., 1990). It is argued here that stimulus audibility must be equated across groups before true differences can be established. In the present investigation, effects of visual biasing on perception were examined as audibility was degraded for 12 young normally hearing listeners. Biasing was determined by quantifying the degree to which listener identification functions for a single synthetic auditory /ba-da-ga/ continuum changed across two conditions: (1)an auditory-only listening condition; and (2)an auditory-visual condition in which every item of the continuum was synchronized with visual articulations of the consonant-vowel (CV) tokens /ba/ and /ga/, as spoken by each of two talkers. Audibility was altered by presenting the conditions in quiet and in noise at each of three signal-to- noise (S/N) ratios. For the visual-/ba/ context, large effects of audibility were found. As audibility decreased, visual biasing increased. A large talker effect also was found, with one talker eliciting more biasing than the other. An independent lipreading measure demonstrated that this talker was more visually intelligible than the other. For the visual-/ga/ context, audibility and talker effects were less robust, possibly obscured by strong listener effects, which were characterized by marked differences in perceptual processing patterns among participants. Some demonstrated substantial biasing whereas others demonstrated little, indicating a strong reliance on audition even in severely degraded acoustic

  6. The Role of Parametric Assumptions in Adaptive Bayesian Estimation

    Science.gov (United States)

    Alcala-Quintana, Rocio; Garcia-Perez, Miguel A.

    2004-01-01

    Variants of adaptive Bayesian procedures for estimating the 5% point on a psychometric function were studied by simulation. Bias and standard error were the criteria to evaluate performance. The results indicated a superiority of (a) uniform priors, (b) model likelihood functions that are odd symmetric about threshold and that have parameter…

  7. Forces in molecules.

    Science.gov (United States)

    Hernández-Trujillo, Jesús; Cortés-Guzmán, Fernando; Fang, De-Chai; Bader, Richard F W

    2007-01-01

    Chemistry is determined by the electrostatic forces acting within a collection of nuclei and electrons. The attraction of the nuclei for the electrons is the only attractive force in a molecule and is the force responsible for the bonding between atoms. This is the attractive force acting on the electrons in the Ehrenfest force and on the nuclei in the Feynman force, one that is countered by the repulsion between the electrons in the former and by the repulsion between the nuclei in the latter. The virial theorem relates these forces to the energy changes resulting from interactions between atoms. All bonding, as signified by the presence of a bond path, has a common origin in terms of the mechanics determined by the Ehrenfest, Feynman and virial theorems. This paper is concerned in particular with the mechanics of interaction encountered in what are classically described as 'nonbonded interactions'--are atoms that 'touch' bonded or repelling one another? PMID:17328425

  8. Forces in molecules.

    Science.gov (United States)

    Hernández-Trujillo, Jesús; Cortés-Guzmán, Fernando; Fang, De-Chai; Bader, Richard F W

    2007-01-01

    Chemistry is determined by the electrostatic forces acting within a collection of nuclei and electrons. The attraction of the nuclei for the electrons is the only attractive force in a molecule and is the force responsible for the bonding between atoms. This is the attractive force acting on the electrons in the Ehrenfest force and on the nuclei in the Feynman force, one that is countered by the repulsion between the electrons in the former and by the repulsion between the nuclei in the latter. The virial theorem relates these forces to the energy changes resulting from interactions between atoms. All bonding, as signified by the presence of a bond path, has a common origin in terms of the mechanics determined by the Ehrenfest, Feynman and virial theorems. This paper is concerned in particular with the mechanics of interaction encountered in what are classically described as 'nonbonded interactions'--are atoms that 'touch' bonded or repelling one another?

  9. Quantum fictitious forces

    Energy Technology Data Exchange (ETDEWEB)

    Bialynicki-Birula, I. [Center for Theoretical Physics, Polish Academy of Sciences, Warsaw (Poland); Abt. fuer Quantenphysik, Univ. Ulm, Ulm (Germany); Cirone, M.A.; Straub, F.; Schleich, W.P. [Abt. fuer Quantenphysik, Univ. Ulm, Ulm (Germany); Dahl, J.P. [Abt. fuer Quantenphysik, Univ. Ulm, Ulm (Germany); Chemical Physics, Dept. of Chemistry, Technical Univ. of Denmark, Lyngby (Denmark); Seligman, T.H. [Centro de Ciencias Fisicas, Univ. of Mexico (UNAM), Cuernavaca (Mexico)

    2002-07-01

    We present Heisenberg's equation of motion for the radial variable of a free non-relativistic particle in D dimensions. The resulting radial force consists of three contributions: (i) the quantum fictitious force which is either attractive or repulsive depending on the number of dimensions, (ii) a singular quantum force located at the origin, and (iii) the centrifugal force associated with non-vanishing angular momentum. Moreover, we use Heisenberg's uncertainty relation to introduce a lower bound for the kinetic energy of an ensemble of neutral particles. This bound is quadratic in the number of atoms and can be traced back to the repulsive quantum fictitious potential. All three forces arise for a free particle: ''Force without force''. (orig.)

  10. Single-Receiver GPS Phase Bias Resolution

    Science.gov (United States)

    Bertiger, William I.; Haines, Bruce J.; Weiss, Jan P.; Harvey, Nathaniel E.

    2010-01-01

    Existing software has been modified to yield the benefits of integer fixed double-differenced GPS-phased ambiguities when processing data from a single GPS receiver with no access to any other GPS receiver data. When the double-differenced combination of phase biases can be fixed reliably, a significant improvement in solution accuracy is obtained. This innovation uses a large global set of GPS receivers (40 to 80 receivers) to solve for the GPS satellite orbits and clocks (along with any other parameters). In this process, integer ambiguities are fixed and information on the ambiguity constraints is saved. For each GPS transmitter/receiver pair, the process saves the arc start and stop times, the wide-lane average value for the arc, the standard deviation of the wide lane, and the dual-frequency phase bias after bias fixing for the arc. The second step of the process uses the orbit and clock information, the bias information from the global solution, and only data from the single receiver to resolve double-differenced phase combinations. It is called "resolved" instead of "fixed" because constraints are introduced into the problem with a finite data weight to better account for possible errors. A receiver in orbit has much shorter continuous passes of data than a receiver fixed to the Earth. The method has parameters to account for this. In particular, differences in drifting wide-lane values must be handled differently. The first step of the process is automated, using two JPL software sets, Longarc and Gipsy-Oasis. The resulting orbit/clock and bias information files are posted on anonymous ftp for use by any licensed Gipsy-Oasis user. The second step is implemented in the Gipsy-Oasis executable, gd2p.pl, which automates the entire process, including fetching the information from anonymous ftp

  11. The Behavioural Biogeosciences: Moving Beyond Evolutionary Adaptation and Innate Reasoning

    Science.gov (United States)

    Glynn, P. D.

    2014-12-01

    Human biases and heuristics reflect adaptation over our evolutionary past to frequently experienced situations that affected our survival and that provided sharp distinguished feedbacks at the level of the individual. Human behavior, however, is not well adapted to the more diffusely experienced (i.e. less immediately/locally acute) problems and issues that scientists and society often seek to address today. Several human biases are identified that affect how science is conducted and used. These biases include an innate discounting of less visible phenomena/systems and of long-term perspectives; as well as a general lack of consideration of the coupling between the resources that we use and the waste that we consequently produce. Other biases include strong beliefs in human exceptionalism and separatedness from "nature". Francis Bacon (The New Organon, 1620) provided a classification of the factors, of the "idols of the mind", that bias pursuit of greater knowledge. How can we address these biases and the factors that affect behaviour and pursuit of knowledge; and ultimately impact the sustainability and resilience of human societies, resources and environments? A process for critical analysis is proposed that solicits explicit accounting and cognizance of these potential human biases and factors. Seeking a greater diversity of independant perspectives is essential: in both the conduct of science and in its application to the management of natural resources and environments. Accountability, traceability and structured processes are critical in this endeavor. The scientific methods designed during the industrial revolution are necessary, but insufficient, in addressing the issues of today. A new area of study in "the behavioral biogeosciences" is suggested that counters, or at least closely re-evaluates, our normal (i.e. adapted) human priorities of observation and study, as well as our judgements and decision-making.

  12. Sparse regularization for force identification using dictionaries

    Science.gov (United States)

    Qiao, Baijie; Zhang, Xingwu; Wang, Chenxi; Zhang, Hang; Chen, Xuefeng

    2016-04-01

    The classical function expansion method based on minimizing l2-norm of the response residual employs various basis functions to represent the unknown force. Its difficulty lies in determining the optimum number of basis functions. Considering the sparsity of force in the time domain or in other basis space, we develop a general sparse regularization method based on minimizing l1-norm of the coefficient vector of basis functions. The number of basis functions is adaptively determined by minimizing the number of nonzero components in the coefficient vector during the sparse regularization process. First, according to the profile of the unknown force, the dictionary composed of basis functions is determined. Second, a sparsity convex optimization model for force identification is constructed. Third, given the transfer function and the operational response, Sparse reconstruction by separable approximation (SpaRSA) is developed to solve the sparse regularization problem of force identification. Finally, experiments including identification of impact and harmonic forces are conducted on a cantilever thin plate structure to illustrate the effectiveness and applicability of SpaRSA. Besides the Dirac dictionary, other three sparse dictionaries including Db6 wavelets, Sym4 wavelets and cubic B-spline functions can also accurately identify both the single and double impact forces from highly noisy responses in a sparse representation frame. The discrete cosine functions can also successfully reconstruct the harmonic forces including the sinusoidal, square and triangular forces. Conversely, the traditional Tikhonov regularization method with the L-curve criterion fails to identify both the impact and harmonic forces in these cases.

  13. Adaptive Image Denoising by Mixture Adaptation.

    Science.gov (United States)

    Luo, Enming; Chan, Stanley H; Nguyen, Truong Q

    2016-10-01

    We propose an adaptive learning procedure to learn patch-based image priors for image denoising. The new algorithm, called the expectation-maximization (EM) adaptation, takes a generic prior learned from a generic external database and adapts it to the noisy image to generate a specific prior. Different from existing methods that combine internal and external statistics in ad hoc ways, the proposed algorithm is rigorously derived from a Bayesian hyper-prior perspective. There are two contributions of this paper. First, we provide full derivation of the EM adaptation algorithm and demonstrate methods to improve the computational complexity. Second, in the absence of the latent clean image, we show how EM adaptation can be modified based on pre-filtering. The experimental results show that the proposed adaptation algorithm yields consistently better denoising results than the one without adaptation and is superior to several state-of-the-art algorithms. PMID:27416593

  14. Ligation bias in illumina next-generation DNA libraries: implications for sequencing ancient genomes.

    Directory of Open Access Journals (Sweden)

    Andaine Seguin-Orlando

    Full Text Available Ancient DNA extracts consist of a mixture of endogenous molecules and contaminant DNA templates, often originating from environmental microbes. These two populations of templates exhibit different chemical characteristics, with the former showing depurination and cytosine deamination by-products, resulting from post-mortem DNA damage. Such chemical modifications can interfere with the molecular tools used for building second-generation DNA libraries, and limit our ability to fully characterize the true complexity of ancient DNA extracts. In this study, we first use fresh DNA extracts to demonstrate that library preparation based on adapter ligation at AT-overhangs are biased against DNA templates starting with thymine residues, contrarily to blunt-end adapter ligation. We observe the same bias on fresh DNA extracts sheared on Bioruptor, Covaris and nebulizers. This contradicts previous reports suggesting that this bias could originate from the methods used for shearing DNA. This also suggests that AT-overhang adapter ligation efficiency is affected in a sequence-dependent manner and results in an uneven representation of different genomic contexts. We then show how this bias could affect the base composition of ancient DNA libraries prepared following AT-overhang ligation, mainly by limiting the ability to ligate DNA templates starting with thymines and therefore deaminated cytosines. This results in particular nucleotide misincorporation damage patterns, deviating from the signature generally expected for authenticating ancient sequence data. Consequently, we show that models adequate for estimating post-mortem DNA damage levels must be robust to the molecular tools used for building ancient DNA libraries.

  15. Ligation bias in illumina next-generation DNA libraries: implications for sequencing ancient genomes.

    Science.gov (United States)

    Seguin-Orlando, Andaine; Schubert, Mikkel; Clary, Joel; Stagegaard, Julia; Alberdi, Maria T; Prado, José Luis; Prieto, Alfredo; Willerslev, Eske; Orlando, Ludovic

    2013-01-01

    Ancient DNA extracts consist of a mixture of endogenous molecules and contaminant DNA templates, often originating from environmental microbes. These two populations of templates exhibit different chemical characteristics, with the former showing depurination and cytosine deamination by-products, resulting from post-mortem DNA damage. Such chemical modifications can interfere with the molecular tools used for building second-generation DNA libraries, and limit our ability to fully characterize the true complexity of ancient DNA extracts. In this study, we first use fresh DNA extracts to demonstrate that library preparation based on adapter ligation at AT-overhangs are biased against DNA templates starting with thymine residues, contrarily to blunt-end adapter ligation. We observe the same bias on fresh DNA extracts sheared on Bioruptor, Covaris and nebulizers. This contradicts previous reports suggesting that this bias could originate from the methods used for shearing DNA. This also suggests that AT-overhang adapter ligation efficiency is affected in a sequence-dependent manner and results in an uneven representation of different genomic contexts. We then show how this bias could affect the base composition of ancient DNA libraries prepared following AT-overhang ligation, mainly by limiting the ability to ligate DNA templates starting with thymines and therefore deaminated cytosines. This results in particular nucleotide misincorporation damage patterns, deviating from the signature generally expected for authenticating ancient sequence data. Consequently, we show that models adequate for estimating post-mortem DNA damage levels must be robust to the molecular tools used for building ancient DNA libraries.

  16. Thinking in Black and White: Conscious thought increases racially biased judgments through biased face memory.

    Science.gov (United States)

    Strick, Madelijn; Stoeckart, Peter F; Dijksterhuis, Ap

    2015-11-01

    It is a common research finding that conscious thought helps people to avoid racial discrimination. These three experiments, however, illustrate that conscious thought may increase biased face memory, which leads to increased judgment bias (i.e., preferring White to Black individuals). In Experiments 1 and 2, university students formed impressions of Black and White housemate candidates. They judged the candidates either immediately (immediate decision condition), thought about their judgments for a few minutes (conscious thought condition), or performed an unrelated task for a few minutes (unconscious thought condition). Conscious thinkers and immediate decision-makers showed a stronger face memory bias than unconscious thinkers, and this mediated increased judgment bias, although not all results were significant. Experiment 3 used a new, different paradigm and showed that a Black male was remembered as darker after a period of conscious thought than after a period of unconscious thought. Implications for racial prejudice are discussed. PMID:26164254

  17. Design and Analysis of a BLPC Vocoder with Probe Noise for Adaptive Feedback Cancellation

    DEFF Research Database (Denmark)

    Kar, Asutosh; Swamy, M.N.S.; Anand, Ankita

    2017-01-01

    a BLPC vocoderbased adaptive feedback canceller with probe noise with an objective of reducing the low-frequency bias in digital hearing-aids. A step-wise mathematical analysis of the proposed feedback canceller is presented employing the recursive least square and normalized least mean square adaptive...

  18. Co-resident and absent mothers: Motherhood and labour force participation in South Africa

    OpenAIRE

    Dorrit, Posel; Gabrielle, van der Stoep

    2008-01-01

    The effects of motherhood on women's labour force participation are estimated usually for mothers who are co-resident with their children. This paper, however, shows that a co-residency requirement upwardly biases the negative effects of motherhood in a country where labour force participation includes (temporary) migration to places of employment. In contrast to co-resident mothers in South Africa, not co-resident mothers are significantly more likely to be labour force participants. The...

  19. Where Has All the Bias Gone? Detecting Gender Bias in the Intrahousehold Allocation of Educational Expenditure

    OpenAIRE

    Kingdon, Geeta Gandhi

    2005-01-01

    The reliability of the household consumption-based (Engel curve) methodology in detecting gender bias has been called into question because it has generally failed to confirm bias even where it exists. This article seeks to find explanations for this failure by exploiting a data set that has educational expenditure information at the individual level and also, by aggregation, at the household level. I find that, in the basic education age groups, the discriminatory mechanism in education is v...

  20. Selection and Biased Gene Conversion in a Multigene Family: Consequences of Interallelic Bias and Threshold Selection

    OpenAIRE

    Walsh, James Bruce

    1986-01-01

    In a previous paper, I investigated the interactions in a gene family of additive selection and biased gene conversion in a finite population when conversion events are rare. Here I extend my "weak-conversion limit" model by allowing biased interallelic conversion (conversion between alleles at the same locus) of arbitrary frequency and various threshold selection schemes for rare interlocus conversion events. I suggest that it is not unreasonable for gene families to experience threshold fit...

  1. Traditions in spider monkeys are biased towards the social domain.

    Directory of Open Access Journals (Sweden)

    Claire J Santorelli

    Full Text Available Cross-site comparison studies of behavioral variation can provide evidence for traditions in wild species once ecological and genetic factors are excluded as causes for cross-site differences. These studies ensure behavior variants are considered within the context of a species' ecology and evolutionary adaptations. We examined wide-scale geographic variation in the behavior of spider monkeys (Ateles geoffroyi across five long-term field sites in Central America using a well established ethnographic cross-site survey method. Spider monkeys possess a relatively rare social system with a high degree of fission-fusion dynamics, also typical of chimpanzees (Pan troglodytes and humans (Homo sapiens. From the initial 62 behaviors surveyed 65% failed to meet the necessary criteria for traditions. The remaining 22 behaviors showed cross-site variation in occurrence ranging from absent through to customary, representing to our knowledge, the first documented cases of traditions in this taxon and only the second case of multiple traditions in a New World monkey species. Of the 22 behavioral variants recorded across all sites, on average 57% occurred in the social domain, 19% in food-related domains and 24% in other domains. This social bias contrasts with the food-related bias reported in great ape cross-site comparison studies and has implications for the evolution of human culture. No pattern of geographical radiation was found in relation to distance across sites. Our findings promote A. geoffroyi as a model species to investigate traditions with field and captive based experiments and emphasize the importance of the social domain for the study of animal traditions.

  2. Addressing bias in the forensic assessment of sexual harassment claims.

    Science.gov (United States)

    Gold, L H

    1998-01-01

    This article addresses unique biases that arise in the assessment of sexual harassment claims by forensic psychiatrists. These include gender biases, diagnostic biases, sociopolitical biases, and bias that arises from lack of knowledge regarding sexual harassment or lack of formal psychiatric training. Forensic psychiatrists are ethically obligated to strive for objectivity and honesty in their assessments. By becoming aware of these biases and attempting to minimize them, we can meet our ethical obligations as forensic psychiatrists. In addition, we can provide more credible and valuable assessments to the courts in this increasingly litigated and partisan issue. PMID:9894213

  3. Equivalent body-force model for magnetostrictive transduction in EMATs

    Science.gov (United States)

    Nagy, Peter B.; Ribichini, Remo

    2015-03-01

    Electromagnetic Acoustic Transducers (EMATs) are an attractive alternative to standard piezoelectric probes in those applications where couplant fluid cannot be used, i.e. high speed or high temperature testing, or when specific wave-modes have to be excited. When used on ferromagnetic samples, EMATs generate elastic waves through three different transduction mechanisms: the Lorentz force, the magnetization force and magnetostriction. The modeling of such phenomena has drawn the attention of several researchers, leading to different physical formalizations, especially for magnetostriction, being the most complex mechanism. This work presents a physics-based model for tangential bias field magnetostrictive EMATs employing surface tractions equivalent to the inertia body forces caused by magnetostrictive strains. This type of modeling had been previously used to validate a Finite Element model for normal bias field EMATs and here is extended to the tangential bias field configuration. Moreover, it is shown that the proposed model is equivalent to a recently developed method using the spatial convolution integral of body forces with Green's tensor to model elastic wave generation in a solid half-space.

  4. When bias binds: Effect of implicit outgroup bias on ingroup affiliation.

    Science.gov (United States)

    Jacoby-Senghor, Drew S; Sinclair, Stacey; Smith, Colin Tucker

    2015-09-01

    We tested a novel process we term implicit homophily in which perceivers' implicit outgroup bias shapes their affiliative responses toward ingroup targets with outgroup friends as a function of perceived similarity. Across 4 studies, we tested implicit homophily in the context of racial groups. We found that White participants with higher implicit anti-Black bias reported less affiliative responses toward White targets with Black friends compared with White targets with White friends, and this effect persisted above and beyond the effects of implicit pro-White bias and explicit racial bias (Studies 1-3). We further found evidence that this relationship between implicit anti-Black bias and affiliation exists because participants infer how comfortable targets are around outgroup members (Preliminary Study) and use this information to infer similarity on this dimension (Studies 1-3). Our findings also suggested that stigma transference and expectancy violation were not viable alternative mediators (Preliminary Study and Study 1). Finally, women's implicit anti-Black bias predicted their likelihood of having Facebook friends with Black friends, providing ecological and behavioral evidence of implicit homophily (Study 4). Implications for research on stigma by association, extended contact, affiliation, and network formation are discussed. PMID:26280842

  5. Nonlinear Dynamic Force Spectroscopy

    CERN Document Server

    Björnham, Oscar

    2016-01-01

    Dynamic force spectroscopy (DFS) is an experimental technique that is commonly used to assess information of the strength, energy landscape, and lifetime of noncovalent bio-molecular interactions. DFS traditionally requires an applied force that increases linearly with time so that the bio-complex under investigation is exposed to a constant loading rate. However, tethers or polymers can modulate the applied force in a nonlinear regime. For example, bacterial adhesion pili and polymers with worm-like chain properties are examples of structures that show nonlinear force responses. In these situations, the theory for traditional DFS cannot be readily applied. In this work we expand the theory for DFS to also include nonlinear external forces while still maintaining compatibility with the linear DFS theory. To validate the theory we modeled a bio-complex expressed on a stiff, an elastic and a worm-like chain polymer, using Monte Carlo methods, and assessed the corresponding rupture force spectra. It was found th...

  6. Biases in simulation of the rice phenology models when applied in warmer climates

    Science.gov (United States)

    Zhang, T.; Li, T.; Yang, X.; Simelton, E.

    2015-12-01

    The current model inter-comparison studies highlight the difference in projections between crop models when they are applied to warmer climates, but these studies do not provide results on how the accuracy of the models would change in these projections because the adequate observations under largely diverse growing season temperature (GST) are often unavailable. Here, we investigate the potential changes in the accuracy of rice phenology models when these models were applied to a significantly warmer climate. We collected phenology data from 775 trials with 19 cultivars in 5 Asian countries (China, India, Philippines, Bangladesh and Thailand). Each cultivar encompasses the phenology observations under diverse GST regimes. For a given rice cultivar in different trials, the GST difference reaches 2.2 to 8.2°C, which allows us to calibrate the models under lower GST and validate under higher GST (i.e., warmer climates). Four common phenology models representing major algorithms on simulations of rice phenology, and three model calibration experiments were conducted. The results suggest that the bilinear and beta models resulted in gradually increasing phenology bias (Figure) and double yield bias per percent increase in phenology bias, whereas the growing-degree-day (GDD) and exponential models maintained a comparatively constant bias when applied in warmer climates (Figure). Moreover, the bias of phenology estimated by the bilinear and beta models did not reduce with increase in GST when all data were used to calibrate models. These suggest that variations in phenology bias are primarily attributed to intrinsic properties of the respective phenology model rather than on the calibration dataset. Therefore we conclude that using the GDD and exponential models has more chances of predicting rice phenology correctly and thus, production under warmer climates, and result in effective agricultural strategic adaptation to and mitigation of climate change.

  7. RNA preservation agents and nucleic acid extraction method bias perceived bacterial community composition.

    Directory of Open Access Journals (Sweden)

    Ann McCarthy

    Full Text Available Bias is a pervasive problem when characterizing microbial communities. An important source is the difference in lysis efficiencies of different populations, which vary depending on the extraction protocol used. To avoid such biases impacting comparisons between gene and transcript abundances in the environment, the use of one protocol that simultaneously extracts both types of nucleic acids from microbial community samples has gained popularity. However, knowledge regarding tradeoffs to combined nucleic acid extraction protocols is limited, particularly regarding yield and biases in the observed community composition. Here, we evaluated a commercially available protocol for simultaneous extraction of DNA and RNA, which we adapted for freshwater microbial community samples that were collected on filters. DNA and RNA yields were comparable to other commonly used, but independent DNA and RNA extraction protocols. RNA protection agents benefited RNA quality, but decreased DNA yields significantly. Choice of extraction protocol influenced the perceived bacterial community composition, with strong method-dependent biases observed for specific phyla such as the Verrucomicrobia. The combined DNA/RNA extraction protocol detected significantly higher levels of Verrucomicrobia than the other protocols, and those higher numbers were confirmed by microscopic analysis. Use of RNA protection agents as well as independent sequencing runs caused a significant shift in community composition as well, albeit smaller than the shift caused by using different extraction protocols. Despite methodological biases, sample origin was the strongest determinant of community composition. However, when the abundance of specific phylogenetic groups is of interest, researchers need to be aware of the biases their methods introduce. This is particularly relevant if different methods are used for DNA and RNA extraction, in addition to using RNA protection agents only for RNA

  8. Reduction of Pavlovian Bias in Schizophrenia: Enhanced Effects in Clozapine-Administered Patients.

    Directory of Open Access Journals (Sweden)

    Matthew A Albrecht

    Full Text Available The negative symptoms of schizophrenia (SZ are associated with a pattern of reinforcement learning (RL deficits likely related to degraded representations of reward values. However, the RL tasks used to date have required active responses to both reward and punishing stimuli. Pavlovian biases have been shown to affect performance on these tasks through invigoration of action to reward and inhibition of action to punishment, and may be partially responsible for the effects found in patients. Forty-five patients with schizophrenia and 30 demographically-matched controls completed a four-stimulus reinforcement learning task that crossed action ("Go" or "NoGo" and the valence of the optimal outcome (reward or punishment-avoidance, such that all combinations of action and outcome valence were tested. Behaviour was modelled using a six-parameter RL model and EEG was simultaneously recorded. Patients demonstrated a reduction in Pavlovian performance bias that was evident in a reduced Go bias across the full group. In a subset of patients administered clozapine, the reduction in Pavlovian bias was enhanced. The reduction in Pavlovian bias in SZ patients was accompanied by feedback processing differences at the time of the P3a component. The reduced Pavlovian bias in patients is suggested to be due to reduced fidelity in the communication between striatal regions and frontal cortex. It may also partially account for previous findings of poorer "Go-learning" in schizophrenia where "Go" responses or Pavlovian consistent responses are required for optimal performance. An attenuated P3a component dynamic in patients is consistent with a view that deficits in operant learning are due to impairments in adaptively using feedback to update representations of stimulus value.

  9. Reduction of Pavlovian Bias in Schizophrenia: Enhanced Effects in Clozapine-Administered Patients.

    Science.gov (United States)

    Albrecht, Matthew A; Waltz, James A; Cavanagh, James F; Frank, Michael J; Gold, James M

    2016-01-01

    The negative symptoms of schizophrenia (SZ) are associated with a pattern of reinforcement learning (RL) deficits likely related to degraded representations of reward values. However, the RL tasks used to date have required active responses to both reward and punishing stimuli. Pavlovian biases have been shown to affect performance on these tasks through invigoration of action to reward and inhibition of action to punishment, and may be partially responsible for the effects found in patients. Forty-five patients with schizophrenia and 30 demographically-matched controls completed a four-stimulus reinforcement learning task that crossed action ("Go" or "NoGo") and the valence of the optimal outcome (reward or punishment-avoidance), such that all combinations of action and outcome valence were tested. Behaviour was modelled using a six-parameter RL model and EEG was simultaneously recorded. Patients demonstrated a reduction in Pavlovian performance bias that was evident in a reduced Go bias across the full group. In a subset of patients administered clozapine, the reduction in Pavlovian bias was enhanced. The reduction in Pavlovian bias in SZ patients was accompanied by feedback processing differences at the time of the P3a component. The reduced Pavlovian bias in patients is suggested to be due to reduced fidelity in the communication between striatal regions and frontal cortex. It may also partially account for previous findings of poorer "Go-learning" in schizophrenia where "Go" responses or Pavlovian consistent responses are required for optimal performance. An attenuated P3a component dynamic in patients is consistent with a view that deficits in operant learning are due to impairments in adaptively using feedback to update representations of stimulus value. PMID:27044008

  10. Relativistic Linear Restoring Force

    Science.gov (United States)

    Clark, D.; Franklin, J.; Mann, N.

    2012-01-01

    We consider two different forms for a relativistic version of a linear restoring force. The pair comes from taking Hooke's law to be the force appearing on the right-hand side of the relativistic expressions: d"p"/d"t" or d"p"/d["tau"]. Either formulation recovers Hooke's law in the non-relativistic limit. In addition to these two forces, we…

  11. Theory of intermolecular forces

    CERN Document Server

    Margenau, H; Ter Haar, D

    1971-01-01

    Theory of Intermolecular Forces deals with the exposition of the principles and techniques of the theory of intermolecular forces. The text focuses on the basic theory and surveys other aspects, with particular attention to relevant experiments. The initial chapters introduce the reader to the history of intermolecular forces. Succeeding chapters present topics on short, intermediate, and long range atomic interactions; properties of Coulomb interactions; shape-dependent forces between molecules; and physical adsorption. The book will be of good use to experts and students of quantum mechanics

  12. Intermolecular and surface forces

    CERN Document Server

    Israelachvili, Jacob N

    2011-01-01

    This reference describes the role of various intermolecular and interparticle forces in determining the properties of simple systems such as gases, liquids and solids, with a special focus on more complex colloidal, polymeric and biological systems. The book provides a thorough foundation in theories and concepts of intermolecular forces, allowing researchers and students to recognize which forces are important in any particular system, as well as how to control these forces. This third edition is expanded into three sections and contains five new chapters over the previous edition.· starts fr

  13. No fifth force?

    Science.gov (United States)

    Maggs, William Ward

    Hopes that geophysicists might be able to document a fifth force of nature have diminished, as new measurements and analyses of earlier geodetic experiments have yielded no solid evidence of a non-Newtonian component of gravity.Modern physics recognizes four fundamental forces with distinct spheres of influence: The strong and weak nuclear forces operate over the range of one atom, while gravity and electromagnetism have an infinite range. Gravity measurements over a few centimeters in laboratories and over millions of kilometers in space continue to buttress Issac Newton's conclusion that the gravitational force between two objects decreases as the square of the distance between them.

  14. Is there gender bias in nursing research?

    Science.gov (United States)

    Polit, Denise F; Beck, Cheryl Tatano

    2008-10-01

    Using data from a consecutive sample of 259 studies published in four leading nursing research journals in 2005-2006, we examined whether nurse researchers favor females as study participants. On average, 75.3% of study participants were female, and 38% of studies had all-female samples. The bias favoring female participants was statistically significant and persistent. The bias was observed regardless of funding source, methodological features, and other participant and researcher characteristics, with one exception: studies that had male investigators had more sex-balanced samples. When designing studies, nurse researchers need to pay close attention to who will benefit from their research and to whether they are leaving out a specific group about which there is a gap in knowledge. PMID:18324681

  15. Biased liquid crystal infiltrated photonic bandgap fiber

    DEFF Research Database (Denmark)

    Weirich, Johannes; Lægsgaard, Jesper; Scolari, Lara;

    2009-01-01

    A simulation scheme for the transmission spectrum of a photonic crystal fiber infiltrated with a nematic liquid crystal and subject to an external bias is presented. The alignment of the biased liquid crystal is simulated using the finite element method to solve the relevant system of coupled...... partial differential equations. From the liquid crystal alignment the full tensorial dielectric permittivity in the capillaries is derived. The transmission spectrum for the photonic crystal fiber is obtained by solving the generalized eigenvalue problem deriving from Maxwell’s equations using a vector...... element based finite element method. We demonstrate results for a splay aligned liquid crystal infiltrated into the capillaries of a four-ring photonic crystal fiber and compare them to corresponding experiments....

  16. Model selection bias and Freedman's paradox

    Science.gov (United States)

    Lukacs, P.M.; Burnham, K.P.; Anderson, D.R.

    2010-01-01

    In situations where limited knowledge of a system exists and the ratio of data points to variables is small, variable selection methods can often be misleading. Freedman (Am Stat 37:152-155, 1983) demonstrated how common it is to select completely unrelated variables as highly "significant" when the number of data points is similar in magnitude to the number of variables. A new type of model averaging estimator based on model selection with Akaike's AIC is used with linear regression to investigate the problems of likely inclusion of spurious effects and model selection bias, the bias introduced while using the data to select a single seemingly "best" model from a (often large) set of models employing many predictor variables. The new model averaging estimator helps reduce these problems and provides confidence interval coverage at the nominal level while traditional stepwise selection has poor inferential properties. ?? The Institute of Statistical Mathematics, Tokyo 2009.

  17. Bias and spread in EVT performance tests.

    Science.gov (United States)

    Smith, J. G.

    1971-01-01

    Performance tests (error probability measurements) of communications systems characterized by low bit rates and high reliability requirements frequently utilize classical extreme value theory (EVT) to avoid the excessive test times encountered with bit error rate (BER) tests. If the underlying noise is Gaussian or perturbed Gaussian, the EVT error estimates have either excessive bias or excessive variance if an insufficient number of test samples is used. EVT is examined to explain the cause of this bias and spread. Experimental verification is made by testing a known Gaussian source, and procedures that minimize these effects are described. It seems apparent that even under the best of conditions the EVT test results are not particularly better than those of BER tests.

  18. Biased trapping issue on weighted hierarchical networks

    Indian Academy of Sciences (India)

    Meifeng Dai; Jie Liu; Feng Zhu

    2014-10-01

    In this paper, we present trapping issues of weight-dependent walks on weighted hierarchical networks which are based on the classic scale-free hierarchical networks. Assuming that edge’s weight is used as local information by a random walker, we introduce a biased walk. The biased walk is that a walker, at each step, chooses one of its neighbours with a probability proportional to the weight of the edge. We focus on a particular case with the immobile trap positioned at the hub node which has the largest degree in the weighted hierarchical networks. Using a method based on generating functions, we determine explicitly the mean first-passage time (MFPT) for the trapping issue. Let parameter (0 < < 1) be the weight factor. We show that the efficiency of the trapping process depends on the parameter a; the smaller the value of a, the more efficient is the trapping process.

  19. Calibration biases in logical reasoning tasks

    Directory of Open Access Journals (Sweden)

    Guillermo Macbeth

    2013-08-01

    Full Text Available The aim of this contribution is to present an experimental study about calibration in deductive reasoning tasks. Calibration is defi ned as the empirical convergence or divergence between the objective and the subjective success. The underconfi dence bias is understood as the dominance of the former over the latter. The hypothesis of this study states that the form of the propositions presented in the experiment is critical for calibration phenomena. Affi rmative and negative propositions are distinguished in their cognitive processing. Results suggests that monotonous compound propositions are prone to underconfi dence. An heuristic approach to this phenomenon is proposed. The activation of a monotony heuristic would produce an illusion of simplicity that generates the calibration bias. These evidence is analysed in the context of the metacognitive modeling of calibration phenomena.

  20. Leveraging Pileup as a Zero Bias Trigger

    CERN Document Server

    Nachman, Benjamin

    2016-01-01

    At the Large Hadron Collider, each event recorded by the ATLAS and CMS collaborations contains many nearly simultaneous pp collisions occurring at nearly the same time as the primary interaction of interest. These pileup collisions are usually a nuisance, degrading the energy resolution of jets and the missing transverse momentum, as well as affecting other reconstructed physics objects. However, interesting processes can also occur in the pileup interactions, and by construction they are recorded without selection bias since the triggering signal originates from the primary interaction in the event. These zero bias events have a large effective prescale, but can be useful for searches and measurements of processes that are difficult or not possible to record with an online trigger. As one example, we show a significant improvement in the sensitivity to low mass dijet resonances using pileup interactions.