WorldWideScience

Sample records for acute dosimetry consensus

  1. BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists and radiation accidents

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, George A. [U.S. Department of Health and Human Services, Office of Preparedness and Emergency Operations, 200 Independence Avenue, SW, Room 403B-1, Washington, DC 20201 (United States); Swartz, Harold M. [Dept. of Radiology and Physiology Dept., Dartmouth Medical School, HB 7785, Vail 702, Rubin 601, Hanover, NH 03755 (United States); Amundson, Sally A. [Center for Radiological Research, Columbia University Medical Center, 630 W. 168th Street, VC11-215, New York, NY 10032 (United States); Blakely, William F. [Armed Forces Radiobiology Research Inst., 8901 Wisconsin Avenue, Bethesda, MD 20889-5603 (United States)], E-mail: blakely@afrri.usuhs.mil; Buddemeier, Brooke [Science and Technology, U.S. Department of Homeland Security, Washington, DC 20528 (United States); Gallez, Bernard [Biomedical Magnetic Resonance Unit and Lab. of Medicinal Chemistry and Radiopharmacy, Univ. Catholique de Louvain, Brussels (Belgium); Dainiak, Nicholas [Dept. of Medicine, Bridgeport Hospital, 267 Grant Street, Bridgeport, CT 06610 (United States); Goans, Ronald E. [MJW Corporation, 1422 Eagle Bend Drive, Clinton, TN 37716-4029 (United States); Hayes, Robert B. [Remote Sensing Lab., MS RSL-47, P.O. Box 98421, Las Vegas, NV 89193 (United States); Lowry, Patrick C. [Radiation Emergency Assistance Center/Training Site (REAC/TS), Oak Ridge Associated Universities, P.O. Box 117, Oak Ridge, TN 37831-0117 (United States); Noska, Michael A. [Food and Drug Administration, FDA/CDRH, 1350 Piccard Drive, HFZ-240, Rockville, MD 20850 (United States); Okunieff, Paul [Dept. of Radiation Oncology (Box 647), Univ. of Rochester, 601 Elmwood Avenue, Rochester, NY 14642 (United States); Salner, Andrew L. [Helen and Harry Gray Cancer Center, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102 (United States); Schauer, David A. [National Council on Radiation Protection and Measurements, 7910 Woodmont Avenue, Suite 400, Bethesda, MD 20814-3095 (United States)] (and others)

    2007-07-15

    , USA; NCRP, 2005. Key elements of preparing emergency responders for nuclear and radiological terrorism. NCRP Commentary No. 19, Bethesda, Maryland, USA] and international [IAEA, 2005. Generic procedures for medical response during a nuclear or radiological emergency. EPR-Medical 2005, IAEA, Vienna, Austria] agencies have reviewed strategies for acute-phase biodosimetry. Consensus biodosimetric guidelines include: (a) clinical signs and symptoms, including peripheral blood counts, time to onset of nausea and vomiting and presence of impaired cognition and neurological deficits, (b) radioactivity assessment, (c) personal and area dosimetry, (d) cytogenetics, (e) in vivo electron paramagnetic resonance (EPR) and (f) other dosimetry approaches (i.e. blood protein assays, etc.). Emerging biodosimetric technologies may further refine triage and dose assessment strategies. However, guidance is needed regarding which biodosimetry techniques are most useful for different radiological scenarios and consensus protocols must be developed. The Local Organizing Committee for the Second International Conference on Biodosimetry and Seventh International Symposium on EPR Dosimetry and Applications (BiodosEPR-2006 Meeting) convened an Acute Dosimetry Consensus Committee composed of national and international experts to: (a) review the current literature for biodosimetry applications for acute-phase applications in radiological emergencies, (b) describe the strengths and weaknesses of each technique, (c) provide recommendations for the use of biodosimetry assays for selected defined radiation scenarios, and (d) develop protocols to apply these recommended biological dosimetry techniques with currently available supplies and equipment for first responders. The Acute Dosimetry Consensus Committee developed recommendations for use of a prioritized multiple-assay biodosimetric-based strategy, concluding that no single assay is sufficiently robust to address all of the potential radiation

  2. BiodosEPR-2006 Meeting: Acute dosimetry consensus committee recommendations on biodosimetry applications in events involving uses of radiation by terrorists and radiation accidents

    International Nuclear Information System (INIS)

    , USA; NCRP, 2005. Key elements of preparing emergency responders for nuclear and radiological terrorism. NCRP Commentary No. 19, Bethesda, Maryland, USA] and international [IAEA, 2005. Generic procedures for medical response during a nuclear or radiological emergency. EPR-Medical 2005, IAEA, Vienna, Austria] agencies have reviewed strategies for acute-phase biodosimetry. Consensus biodosimetric guidelines include: (a) clinical signs and symptoms, including peripheral blood counts, time to onset of nausea and vomiting and presence of impaired cognition and neurological deficits, (b) radioactivity assessment, (c) personal and area dosimetry, (d) cytogenetics, (e) in vivo electron paramagnetic resonance (EPR) and (f) other dosimetry approaches (i.e. blood protein assays, etc.). Emerging biodosimetric technologies may further refine triage and dose assessment strategies. However, guidance is needed regarding which biodosimetry techniques are most useful for different radiological scenarios and consensus protocols must be developed. The Local Organizing Committee for the Second International Conference on Biodosimetry and Seventh International Symposium on EPR Dosimetry and Applications (BiodosEPR-2006 Meeting) convened an Acute Dosimetry Consensus Committee composed of national and international experts to: (a) review the current literature for biodosimetry applications for acute-phase applications in radiological emergencies, (b) describe the strengths and weaknesses of each technique, (c) provide recommendations for the use of biodosimetry assays for selected defined radiation scenarios, and (d) develop protocols to apply these recommended biological dosimetry techniques with currently available supplies and equipment for first responders. The Acute Dosimetry Consensus Committee developed recommendations for use of a prioritized multiple-assay biodosimetric-based strategy, concluding that no single assay is sufficiently robust to address all of the potential radiation

  3. Neuroprotection as initial therapy in acute stroke - Third report of an Ad Hoc Consensus Group Meeting

    NARCIS (Netherlands)

    Bogousslavsky, J; De Keyser, J; Diener, HC; Fieschi, C; Hacke, W; Kaste, M; Orgogozo, JM; Pulsinelli, W; Wahlgren, NG

    1998-01-01

    Although a considerable body of scientific data is now available on neuroprotection in acute ischaemic stroke, this field is not yet established in clinical practice. At its third meeting, the European Ad Hoc Consensus Group considered the potential for neuroprotection in acute stroke and the practi

  4. DOSIMETRY

    CERN Multimedia

    2001-01-01

    From the month of May on, the neutron dosimeter will be worn in an extra package distinct from the usual film-badge. We will give you more ample information in Weekly Bulletin No. 18/2001 of April 30, 2001. In the week following Easter (17 - 20. 4. 2001) the Individual Dosimetry Service will be opened in the mornings from 8:30 to 11:30 h only. The Service will be closed on April 30.

  5. Consensus of primary care in acute pancreatitis in Japan

    Institute of Scientific and Technical Information of China (English)

    Makoto Otsuki; Tetsuhide Ito; Kazuo Inui; Tooru Shimosegawa; Shigeki Tanaka; Keisho Kataoka; Hiromitsu Saisho; Kazuichi Okazaki; Yosikazu Kuroda; Norio Sawabu; Yoshifumi Takeyama; Masahiko Hirota; Shinju Arata; Masaru Koizumi; Shigeyuki Kawa; Terumi Kamisawa; Kazunori Takeda; Toshihiko Mayumi; Motoji Kitagawa

    2006-01-01

    The incidence of acute pancreatitis in Japan is increasing and ranges from 187 to 347 cases per million populations. Case fatality was 0.2% for mild to moderate, and 9.0% for severe acute pancreatitis in Japan in 2003. Experts in pancreatitis in Japan made this document focusing on the practical aspects in the early management of patients with acute pancreatitis.The correct diagnosis of acute pancreatitis and severity stratification should be made in all patients using the criteria for the diagnosis of acute pancreatitis and the multifactor scoring system proposed by the Research Committee of Intractable Diseases of the Pancreas as early as possible. All patients diagnosed with acute pancreatitis should be managed in the hospital.Monitoring of blood pressure, pulse and respiratory rate,body temperature, hourly urinary volume, and blood oxygen saturation level is essential in the management of such patients. Early vigorous intravenous hydration is of foremost importance to stabilize circulatory dynamics. Adequate pain relief with opiates is also important. In severe acute pancreatitis, prophylactic intravenous administration of antibiotics at an early stage is recommended. Administration of protease inhibitors should be initiated as soon as thediagnosis of acute pancreatitis is confirmed. A combination of enteral feeding with parenteral nutrition from early stage is recommended if there are no clear signs and symptoms of ileus and gastrointestinal bleeding. Patients with severe acute pancreatitis should be transferred to ICU as early as possible to perform special measures such as continuous regional arterial infusion of protease inhibitors and antibiotics, and continuous hemodiafiltration. The Japanese Government covers medical care expense for severe acute pancreatitis as one of the projects of Research on Measures for Intractable Diseases.

  6. An evidence and consensus based guideline for acute diarrhoea management

    OpenAIRE

    Armon, K; Stephenson, T; MacFaul, R; Eccleston, P; Werneke, U; Baumer, H

    2001-01-01

    OBJECTIVE—To develop an evidence and consensus based guideline for the management of the child who presents to hospital with diarrhoea (with or without vomiting), a common problem representing 16% of all paediatric medical attenders at an accident and emergency department. Clinical assessment, investigations (biochemistry and stool culture in particular), admission, and treatment are addressed. The guideline aims to aid junior doctors in recognising children who need admi...

  7. Consensus for the manaegment of severe acute respiratory syndrome

    Institute of Scientific and Technical Information of China (English)

    Chinese Medical Association,China Association of C

    2003-01-01

    @@ INTRODUCTION Since recognition of the first case of sever acute respiratory syndrome (SARS) in Guangdong Province in November 2002,health care worker engaged in basic medicine,clinical medicine and preventive progress in the understanding of the etiology,epidemiology,diagnosis,treatment and prevention of SARS.

  8. Cardio-renal syndromes : report from the consensus conference of the Acute Dialysis Quality Initiative

    NARCIS (Netherlands)

    Ronco, Claudio; McCullough, Peter; Anker, Stefan D.; Anand, Inder; Aspromonte, Nadia; Bagshaw, Sean M.; Bellomo, Rinaldo; Berl, Tomas; Bobek, Ilona; Cruz, Dinna N.; Daliento, Luciano; Davenport, Andrew; Haapio, Mikko; Hillege, Hans; House, Andrew A.; Katz, Nevin; Maisel, Alan; Mankad, Sunil; Zanco, Pierluigi; Mebazaa, Alexandre; Palazzuoli, Alberto; Ronco, Federico; Shaw, Andrew; Sheinfeld, Geoff; Soni, Sachin; Vescovo, Giorgio; Zamperetti, Nereo; Ponikowski, Piotr

    2010-01-01

    A consensus conference on cardio-renal syndromes (CRS) was held in Venice Italy, in September 2008 under the auspices of the Acute Dialysis Quality Initiative (ADQI). The following topics were matter of discussion after a systematic literature review and the appraisal of the best available evidence:

  9. Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment

    DEFF Research Database (Denmark)

    Schmiegelow, Kjeld; Attarbaschi, Andishe; Barzilai, Shlomit;

    2016-01-01

    toxic effects, that no two protocols shared identical definitions of all toxic effects, and that no toxic effect definition was shared by all protocols. Using the Delphi method over three face-to-face plenary meetings, consensus definitions were obtained for all 14 toxic effects. In the overall......Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects. This is because reported frequencies vary widely across studies, partly because of diverse definitions of toxic effects. Using the Delphi...... method, 15 international childhood acute lymphoblastic leukaemia study groups assessed acute lymphoblastic leukaemia protocols to address toxic effects that were to be considered by the Ponte di Legno working group. 14 acute toxic effects (hypersensitivity to asparaginase, hyperlipidaemia, osteonecrosis...

  10. UNDERSTANDING THE INTERNATIONAL CONSENSUS FOR ACUTE PANCREATITIS: CLASSIFICATION OF ATLANTA 2012

    Science.gov (United States)

    de SOUZA, Gleim Dias; SOUZA, Luciana Rodrigues Queiroz; CUENCA, Ronaldo Máfia; JERÔNIMO, Bárbara Stephane de Medeiros; de SOUZA, Guilherme Medeiros; VILELA, Vinícius Martins

    2016-01-01

    ABSTRACT Introduction: Contrast computed tomography and magnetic resonance imaging are widely used due to its image quality and ability to study pancreatic and peripancreatic morphology. The understanding of the various subtypes of the disease and identification of possible complications requires a familiarity with the terminology, which allows effective communication between the different members of the multidisciplinary team. Aim: Demonstrate the terminology and parameters to identify the different classifications and findings of the disease based on the international consensus for acute pancreatitis ( Atlanta Classification 2012). Methods: Search and analysis of articles in the "CAPES Portal de Periódicos with headings "acute pancreatitis" and "Atlanta Review". Results: Were selected 23 articles containing radiological descriptions, management or statistical data related to pathology. Additional statistical data were obtained from Datasus and Population Census 2010. The radiological diagnostic criterion adopted was the Radiology American College system. The "acute pancreatitis - 2012 Rating: Review Atlanta classification and definitions for international consensus" tries to eliminate inconsistency and divergence from the determination of uniformity to the radiological findings, especially the terminology related to fluid collections. More broadly as "pancreatic abscess" and "phlegmon" went into disuse and the evolution of the collection of patient fluids can be described as "acute peripancreatic collections", "acute necrotic collections", "pseudocyst" and "necrosis pancreatic walled or isolated". Conclusion: Computed tomography and magnetic resonance represent the best techniques with sequential images available for diagnosis. Standardization of the terminology is critical and should improve the management of patients with multiple professionals care, risk stratification and adequate treatment. PMID:27759788

  11. [SEIP-SERPE-SEOP Consensus document on the treatment of uncomplicated acute osteomyelitis and septic arthritis].

    Science.gov (United States)

    Saavedra-Lozano, J; Calvo, C; Huguet Carol, R; Rodrigo, C; Núñez, E; Obando, I; Rojo, P; Merino, R; Pérez, C; Downey, F J; Colino, E; García, J J; Cilleruelo, M J; Torner, F; García, L

    2015-04-01

    This is a Consensus Document of the Spanish Society of Paediatric Infectious Diseases (Sociedad Española de Infectología Pediatrica), Spanish Society of Paediatric Rheumatology (Sociedad Española de Reumatología Pediátrica) and the Spanish Society of Paediatric Orthopaedics (Sociedad Española de Ortopedia Pediátrica), on the treatment of uncomplicated acute osteomyelitis and septic arthritis. A review is presented on the medical and surgical treatment of acute osteoarticular infection, defined as a process with less than 14 days of symptomatology, uncomplicated and community-acquired. The different possible options are evaluated based on the best available scientific knowledge, and a number of evidence-based recommendations for clinical practice are provided.

  12. A modern Monte Carlo investigation of the TG-43 dosimetry parameters for an {sup 125}I seed already having AAPM consensus data

    Energy Technology Data Exchange (ETDEWEB)

    Aryal, Prakash; Molloy, Janelle A. [Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky 40536 (United States); Rivard, Mark J., E-mail: mark.j.rivard@gmail.com [Department of Radiation Oncology, Tufts University School of Medicine, Boston, Massachusetts 02111 (United States)

    2014-02-15

    Purpose: To investigate potential causes for differences in TG-43 brachytherapy dosimetry parameters in the existent literature for the model IAI-125A{sup 125}I seed and to propose new standard dosimetry parameters. Methods: The MCNP5 code was used for Monte Carlo (MC) simulations. Sensitivity of dose distributions, and subsequently TG-43 dosimetry parameters, was explored to reproduce historical methods upon which American Association of Physicists in Medicine (AAPM) consensus data are based. Twelve simulation conditions varying{sup 125}I coating thickness, coating mass density, photon interaction cross-section library, and photon emission spectrum were examined. Results: Varying{sup 125}I coating thickness, coating mass density, photon cross-section library, and photon emission spectrum for the model IAI-125A seed changed the dose-rate constant by up to 0.9%, about 1%, about 3%, and 3%, respectively, in comparison to the proposed standard value of 0.922 cGy h{sup −1} U{sup −1}. The dose-rate constant values by Solberg et al. [“Dosimetric parameters of three new solid core {sup 125}I brachytherapy sources,” J. Appl. Clin. Med. Phys. 3, 119–134 (2002)], Meigooni et al. [“Experimental and theoretical determination of dosimetric characteristics of IsoAid ADVANTAGE™ {sup 125}I brachytherapy source,” Med. Phys. 29, 2152–2158 (2002)], and Taylor and Rogers [“An EGSnrc Monte Carlo-calculated database of TG-43 parameters,” Med. Phys. 35, 4228–4241 (2008)] for the model IAI-125A seed and Kennedy et al. [“Experimental and Monte Carlo determination of the TG-43 dosimetric parameters for the model 9011 THINSeed™ brachytherapy source,” Med. Phys. 37, 1681–1688 (2010)] for the model 6711 seed were +4.3% (0.962 cGy h{sup −1} U{sup −1}), +6.2% (0.98 cGy h{sup −1} U{sup −1}), +0.3% (0.925 cGy h{sup −1} U{sup −1}), and −0.2% (0.921 cGy h{sup −1} U{sup −1}), respectively, in comparison to the proposed standard

  13. Noninvasive Biomonitoring Approaches to Determine Dosimetry and Risk Following Acute Chemical Exposure: Analysis of Lead or Organophosphate Insecticide in Saliva

    International Nuclear Information System (INIS)

    There is a need to develop approaches for assessing risk associated with acute exposures to a broad-range of chemical agents and to rapidly determine the potential implications to human health. Non-invasive biomonitoring approaches are being developed using reliable portable analytical systems to quantitate dosimetry utilizing readily obtainable body fluids, such as saliva. Saliva has been used to evaluate a broad range of biomarkers, drugs, and environmental contaminants including heavy metals and pesticides. To advance the application of non-invasive biomonitoring a microfluidic/ electrochemical device has also been developed for the analysis of lead (Pb), using square wave anodic stripping voltammetry. The system demonstrates a linear response over a broad concentration range (1 2000 ppb) and is capable of quantitating saliva Pb in rats orally administered acute doses of Pb-acetate. Appropriate pharmacokinetic analyses have been used to quantitate systemic dosimetry based on determination of saliva Pb concentrations. In addition, saliva has recently been used to quantitate dosimetry following exposure to the organophosphate insecticide chlorpyrifos in a rodent model system by measuring the major metabolite, trichloropyridinol, and saliva cholinesterase inhibition following acute exposures. These results suggest that technology developed for non-invasive biomonitoring can provide a sensitive, and portable analytical tool capable of assessing exposure and risk in real-time. By coupling these non-invasive technologies with pharmacokinetic modeling it is feasible to rapidly quantitate acute exposure to a broad range of chemical agents. In summary, it is envisioned that once fully developed, these monitoring and modeling approaches will be useful for accessing acute exposure and health risk

  14. An expert consensus on the evaluation and treatment of acute thoracolumbar spine and spinal cord injury in China

    Institute of Scientific and Technical Information of China (English)

    Zhicheng Zhang; Fang Li; Tiansheng Sun

    2013-01-01

    This is an expert consensus on the evaluation and treatment of thoracolumbar spinal injury, estab-lished from February 2009 to July 2010. The expert consensus consists mainly of six parts with a total of 54 recommendations including the overview (one item);pre-hospital care (one item);evalu-ation and diagnosis (13 items);treatment (23 items); prevention and treatment of major complica-tions (12 items);and rehabilitation (four items). This is the first time that Chinese experts have pub-lished a consensus on spine and spinal cord injury. The expert consensus was established based on Delphi methods, literature analysis, and clinical experiences. Each recommendation is supported by and was interpreted using multi-level evidences. The level of agreement with the recommenda-tion among the panel members was assessed as either low, moderate, or strong. Each panel member was asked to indicate his or her level of agreement on a 5-point scale, with “1” corre-sponding to neutrality and“5”representing maximum agreement. Scores were aggregated across the panel members and an arithmetic mean was calculated. This mean score was then translated into low, moderate, or strong. After al of the votes were col ected and calculated, the results showed no low-level recommendations, 10 moderate-level recommendations, and 44 strong-level recom-mendations. An expert consensus was reached and was recognized by Chinese spine surgeons. Wide-scale adoption of these recommendations is urgent in the management of acute thoracol-umbar spine and spinal cord injury in a broader attempt to create a standard evaluation and treat-ment strategy for acute thoracolumbar spine and spinal cord injury in China.

  15. [SEIP-SERPE-SEOP Consensus Document on aetiopathogenesis and diagnosis of uncomplicated acute osteomyelitis and septic arthritis].

    Science.gov (United States)

    Saavedra-Lozano, J; Calvo, C; Huguet Carol, R; Rodrigo, C; Núñez, E; Pérez, C; Merino, R; Rojo, P; Obando, I; Downey, F J; Colino, E; García, J J; Cilleruelo, M J; Torner, F; García, L

    2015-09-01

    This is a Consensus Document of the Sociedad Española de Infectología Pediátrica, Sociedad Española de Reumatología Pediátrica and Sociedad Española de Ortopedia Pediátrica on the aetiology and diagnosis of uncomplicated acute osteomyelitis and septic arthritis. A review is presented of the aetiopathogenesis and pathophysiology of acute osteoarticular infection defined as a process with less than 14 days of symptomatology, uncomplicated, and community-acquired. The diagnostic approach to these conditions is summarised based on the best available scientific knowledge. Based on this evidence, a number of recommendations for clinical practice are provided.

  16. Dosimetry; La dosimetrie

    Energy Technology Data Exchange (ETDEWEB)

    Le Couteulx, I.; Apretna, D.; Beaugerie, M.F. [Electricite de France (EDF), 75 - Paris (France)] [and others

    2003-07-01

    Eight articles treat the dosimetry. Two articles evaluate the radiation doses in specific cases, dosimetry of patients in radiodiagnosis, three articles are devoted to detectors (neutrons and x and gamma radiations) and a computer code to build up the dosimetry of an accident due to an external exposure. (N.C.)

  17. Cardiorenal Syndromes : An Executive Summary from the Consensus Conference of the Acute Dialysis Quality Initiative (ADQI)

    NARCIS (Netherlands)

    Ronco, Claudio; McCullough, Peter A.; Anker, Stefan D.; Anand, Inder; Aspromonte, Nadia; Bagshaw, Sean M.; Bellomo, Rinaldo; Berl, Tomas; Bobek, Ilona; Cruz, Dinna N.; Daliento, Luciano; Davenport, Andrew; Haapio, Mikko; Hillege, Hans; House, Andrew; Katz, Nevin M.; Maisel, Alan; Mankad, Sunil; Zanco, Pierluigi; Mebazaa, Alexandre; Palazzuoli, Alberto; Ronco, Federico; Shaw, Andrew; Sheinfeld, Geoff; Soni, Sachin; Vescovo, Giorgio; Zamperetti, Nereo; Ponikowski, Piotr; Ronco, C; Bellomo, R; McCullough, PA

    2010-01-01

    The cardiorenal syndrome (CRS) is a disorder of the heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. The general definition has been expanded into five subtypes reflecting the primacy of organ dysfunction and the time-frame of

  18. Pulmonary Specific Ancillary Treatment for Pediatric Acute Respiratory Distress Syndrome : Proceedings From the Pediatric Acute Lung Injury Consensus Conference

    NARCIS (Netherlands)

    Tamburro, Robert F.; Kneyber, Martin C. J.

    2015-01-01

    Objective: To provide an overview of the current literature on pulmonary-specific therapeutic approaches to pediatric acute respiratory distress syndrome to determine recommendations for clinical practice and/or future research. Data Sources: PubMed, EMBASE, CINAHL, SCOPUS, and the Cochrane Library

  19. Acute kidney injury in the era of big data: the 15(th) Consensus Conference of the Acute Dialysis Quality Initiative (ADQI).

    Science.gov (United States)

    Bagshaw, Sean M; Goldstein, Stuart L; Ronco, Claudio; Kellum, John A

    2016-01-01

    The world is immersed in "big data". Big data has brought about radical innovations in the methods used to capture, transfer, store and analyze the vast quantities of data generated every minute of every day. At the same time; however, it has also become far easier and relatively inexpensive to do so. Rapidly transforming, integrating and applying this large volume and variety of data are what underlie the future of big data. The application of big data and predictive analytics in healthcare holds great promise to drive innovation, reduce cost and improve patient outcomes, health services operations and value. Acute kidney injury (AKI) may be an ideal syndrome from which various dimensions and applications built within the context of big data may influence the structure of services delivery, care processes and outcomes for patients. The use of innovative forms of "information technology" was originally identified by the Acute Dialysis Quality Initiative (ADQI) in 2002 as a core concept in need of attention to improve the care and outcomes for patients with AKI. For this 15(th) ADQI consensus meeting held on September 6-8, 2015 in Banff, Canada, five topics focused on AKI and acute renal replacement therapy were developed where extensive applications for use of big data were recognized and/or foreseen. In this series of articles in the Canadian Journal of Kidney Health and Disease, we describe the output from these discussions. PMID:26925244

  20. Acute kidney injury in the era of big data: the 15(th) Consensus Conference of the Acute Dialysis Quality Initiative (ADQI).

    Science.gov (United States)

    Bagshaw, Sean M; Goldstein, Stuart L; Ronco, Claudio; Kellum, John A

    2016-01-01

    The world is immersed in "big data". Big data has brought about radical innovations in the methods used to capture, transfer, store and analyze the vast quantities of data generated every minute of every day. At the same time; however, it has also become far easier and relatively inexpensive to do so. Rapidly transforming, integrating and applying this large volume and variety of data are what underlie the future of big data. The application of big data and predictive analytics in healthcare holds great promise to drive innovation, reduce cost and improve patient outcomes, health services operations and value. Acute kidney injury (AKI) may be an ideal syndrome from which various dimensions and applications built within the context of big data may influence the structure of services delivery, care processes and outcomes for patients. The use of innovative forms of "information technology" was originally identified by the Acute Dialysis Quality Initiative (ADQI) in 2002 as a core concept in need of attention to improve the care and outcomes for patients with AKI. For this 15(th) ADQI consensus meeting held on September 6-8, 2015 in Banff, Canada, five topics focused on AKI and acute renal replacement therapy were developed where extensive applications for use of big data were recognized and/or foreseen. In this series of articles in the Canadian Journal of Kidney Health and Disease, we describe the output from these discussions.

  1. The role of levosimendan in acute heart failure complicating acute coronary syndrome: A review and expert consensus opinion.

    Science.gov (United States)

    Nieminen, Markku S; Buerke, Michael; Cohen-Solál, Alain; Costa, Susana; Édes, István; Erlikh, Alexey; Franco, Fatima; Gibson, Charles; Gorjup, Vojka; Guarracino, Fabio; Gustafsson, Finn; Harjola, Veli-Pekka; Husebye, Trygve; Karason, Kristjan; Katsytadze, Igor; Kaul, Sundeep; Kivikko, Matti; Marenzi, Giancarlo; Masip, Josep; Matskeplishvili, Simon; Mebazaa, Alexandre; Møller, Jacob E; Nessler, Jadwiga; Nessler, Bohdan; Ntalianis, Argyrios; Oliva, Fabrizio; Pichler-Cetin, Emel; Põder, Pentti; Recio-Mayoral, Alejandro; Rex, Steffen; Rokyta, Richard; Strasser, Ruth H; Zima, Endre; Pollesello, Piero

    2016-09-01

    Acute heart failure and/or cardiogenic shock are frequently triggered by ischemic coronary events. Yet, there is a paucity of randomized data on the management of patients with heart failure complicating acute coronary syndrome, as acute coronary syndrome and cardiogenic shock have frequently been defined as exclusion criteria in trials and registries. As a consequence, guideline recommendations are mostly driven by observational studies, even though these patients have a particularly poor prognosis compared to heart failure patients without signs of coronary artery disease. In acute heart failure, and especially in cardiogenic shock related to ischemic conditions, vasopressors and inotropes are used. However, both pathophysiological considerations and available clinical data suggest that these treatments may have disadvantageous effects. The inodilator levosimendan offers potential benefits due to a range of distinct effects including positive inotropy, restoration of ventriculo-arterial coupling, increases in tissue perfusion, and anti-stunning and anti-inflammatory effects. In clinical trials levosimendan improves symptoms, cardiac function, hemodynamics, and end-organ function. Adverse effects are generally less common than with other inotropic and vasoactive therapies, with the notable exception of hypotension. The decision to use levosimendan, in terms of timing and dosing, is influenced by the presence of pulmonary congestion, and blood pressure measurements. Levosimendan should be preferred over adrenergic inotropes as a first line therapy for all ACS-AHF patients who are under beta-blockade and/or when urinary output is insufficient after diuretics. Levosimendan can be used alone or in combination with other inotropic or vasopressor agents, but requires monitoring due to the risk of hypotension. PMID:27232927

  2. Mental and social health during and after acute emergencies: emerging consensus?

    OpenAIRE

    van Ommeren, Mark; Saxena, Shekhar; Saraceno, Benedetto

    2005-01-01

    Mental health care programmes during and after acute emergencies in resource-poor countries have been considered controversial. There is no agreement on the public health value of the post-traumatic stress disorder concept and no agreement on the appropriateness of vertical (separate) trauma-focused services. A range of social and mental health intervention strategies and principles seem, however, to have the broad support of expert opinion. Despite continuing debate, there is emerging agreem...

  3. Applications for detection of acute kidney injury using electronic medical records and clinical information systems: workgroup statements from the 15(th) ADQI Consensus Conference.

    Science.gov (United States)

    James, Matthew T; Hobson, Charles E; Darmon, Michael; Mohan, Sumit; Hudson, Darren; Goldstein, Stuart L; Ronco, Claudio; Kellum, John A; Bagshaw, Sean M

    2016-01-01

    Electronic medical records and clinical information systems are increasingly used in hospitals and can be leveraged to improve recognition and care for acute kidney injury. This Acute Dialysis Quality Initiative (ADQI) workgroup was convened to develop consensus around principles for the design of automated AKI detection systems to produce real-time AKI alerts using electronic systems. AKI alerts were recognized by the workgroup as an opportunity to prompt earlier clinical evaluation, further testing and ultimately intervention, rather than as a diagnostic label. Workgroup members agreed with designing AKI alert systems to align with the existing KDIGO classification system, but recommended future work to further refine the appropriateness of AKI alerts and to link these alerts to actionable recommendations for AKI care. The consensus statements developed in this review can be used as a roadmap for development of future electronic applications for automated detection and reporting of AKI. PMID:26925245

  4. Recommendations on pre-hospital & early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine.

    Science.gov (United States)

    Mebazaa, Alexandre; Yilmaz, M Birhan; Levy, Phillip; Ponikowski, Piotr; Peacock, W Frank; Laribi, Said; Ristic, Arsen D; Lambrinou, Ekaterini; Masip, Josep; Riley, Jillian P; McDonagh, Theresa; Mueller, Christian; deFilippi, Christopher; Harjola, Veli-Pekka; Thiele, Holger; Piepoli, Massimo F; Metra, Marco; Maggioni, Aldo; McMurray, John; Dickstein, Kenneth; Damman, Kevin; Seferovic, Petar M; Ruschitzka, Frank; Leite-Moreira, Adelino F; Bellou, Abdelouahab; Anker, Stefan D; Filippatos, Gerasimos

    2015-06-01

    Acute heart failure is a fatal syndrome. Emergency physicians, cardiologists, intensivists, nurses and other health care providers have to cooperate to provide optimal benefit. However, many treatment decisions are opinion-based and few are evidenced-based. This consensus paper provides guidance to practicing physicians and nurses to manage acute heart failure in the pre-hospital and hospital setting. Criteria of hospitalization and of discharge are described. Gaps in knowledge and perspectives in the management of acute heart failure are also detailed. This consensus paper on acute heart failure might help enable contiguous practice.

  5. Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN.

    Science.gov (United States)

    Wahlgren, Nils; Moreira, Tiago; Michel, Patrik; Steiner, Thorsten; Jansen, Olav; Cognard, Christophe; Mattle, Heinrich P; van Zwam, Wim; Holmin, Staffan; Tatlisumak, Turgut; Petersson, Jesper; Caso, Valeria; Hacke, Werner; Mazighi, Mikael; Arnold, Marcel; Fischer, Urs; Szikora, Istvan; Pierot, Laurent; Fiehler, Jens; Gralla, Jan; Fazekas, Franz; Lees, Kennedy R

    2016-01-01

    The original version of this consensus statement on mechanical thrombectomy was approved at the European Stroke Organisation (ESO)-Karolinska Stroke Update conference in Stockholm, 16-18 November 2014. The statement has later, during 2015, been updated with new clinical trials data in accordance with a decision made at the conference. Revisions have been made at a face-to-face meeting during the ESO Winter School in Berne in February, through email exchanges and the final version has then been approved by each society. The recommendations are identical to the original version with evidence level upgraded by 20 February 2015 and confirmed by 15 May 2015. The purpose of the ESO-Karolinska Stroke Update meetings is to provide updates on recent stroke therapy research and to discuss how the results may be implemented into clinical routine. Selected topics are discussed at consensus sessions, for which a consensus statement is prepared and discussed by the participants at the meeting. The statements are advisory to the ESO guidelines committee. This consensus statement includes recommendations on mechanical thrombectomy after acute stroke. The statement is supported by ESO, European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), and European Academy of Neurology (EAN).

  6. Radiation dosimetry

    CERN Document Server

    Hine, Gerald J; Hine, Gerald J

    1956-01-01

    Radiation Dosimetry focuses on the advancements, processes, technologies, techniques, and principles involved in radiation dosimetry, including counters and calibration and standardization techniques. The selection first offers information on radiation units and the theory of ionization dosimetry and interaction of radiation with matter. Topics include quantities derivable from roentgens, determination of dose in roentgens, ionization dosimetry of high-energy photons and corpuscular radiations, and heavy charged particles. The text then examines the biological and medical effects of radiation,

  7. Dosimetry Service

    CERN Multimedia

    2006-01-01

    Cern Staff and Users can now consult their dose records for an individual or an organizational unit with HRT. Please see more information on our web page: http://cern.ch/rp-dosimetry Dosimetry Service is open every morning from 8.30 - 12.00. Closed in the afternoons. We would like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCT's) must always be returned to the Service after the use and must not be left on the racks in the experimental areas or in the secretariats. Dosimetry Service Tel. 7 2155 Dosimetry.service@cern.ch http://cern.ch/rp-dosimetry

  8. Utilizing electronic health records to predict acute kidney injury risk and outcomes: workgroup statements from the 15(th) ADQI Consensus Conference.

    Science.gov (United States)

    Sutherland, Scott M; Chawla, Lakhmir S; Kane-Gill, Sandra L; Hsu, Raymond K; Kramer, Andrew A; Goldstein, Stuart L; Kellum, John A; Ronco, Claudio; Bagshaw, Sean M

    2016-01-01

    The data contained within the electronic health record (EHR) is "big" from the standpoint of volume, velocity, and variety. These circumstances and the pervasive trend towards EHR adoption have sparked interest in applying big data predictive analytic techniques to EHR data. Acute kidney injury (AKI) is a condition well suited to prediction and risk forecasting; not only does the consensus definition for AKI allow temporal anchoring of events, but no treatments exist once AKI develops, underscoring the importance of early identification and prevention. The Acute Dialysis Quality Initiative (ADQI) convened a group of key opinion leaders and stakeholders to consider how best to approach AKI research and care in the "Big Data" era. This manuscript addresses the core elements of AKI risk prediction and outlines potential pathways and processes. We describe AKI prediction targets, feature selection, model development, and data display. PMID:26925247

  9. ESR Dosimetry

    International Nuclear Information System (INIS)

    ESR dosimetry is widely used for several applications such as dose assessment in accidents, medical applications and sterilization of food and other materials. In this work the dosimetric properties of natural and synthetic Hydroxyapatite, Alanine, and 2-Methylalanine are presented. Recent results on the use of a K-Band (24 GHz) ESR spectrometer in dosimetry are also presented

  10. Dosimetry Service

    CERN Multimedia

    2005-01-01

    Please remember to read your dosimeter at least once a month. Regular read-outs are vital to ensure that your personal dose is periodically monitored. Dosimeters should be read even if you have not visited the controlled areas. Dosimetry Service - Tel. 72155 http://cern.ch/rp-dosimetry

  11. Dosimetry Service

    CERN Multimedia

    2005-01-01

    Please remember to read your dosimeter at least once a month. Regular read-outs are vital to ensure that your personal dose is periodically monitored. Dosimeters should be read even if you have not visited the controlled areas. Dosimetry Service Tel. 7 2155 http://cern.ch/rp-dosimetry

  12. Dosimetry Service

    CERN Multimedia

    2005-01-01

    Please remember to read your dosimeter at least once a month. Regular read-outs are vital to ensure that your personal dose is periodically monitored. Dosimeters should be read even if you have not visited the controlled areas. Dosimetry Service - Tel. 7 2155 http://cern.ch/rp-dosimetry

  13. Computational dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Siebert, B.R.L.; Thomas, R.H.

    1996-01-01

    The paper presents a definition of the term ``Computational Dosimetry`` that is interpreted as the sub-discipline of computational physics which is devoted to radiation metrology. It is shown that computational dosimetry is more than a mere collection of computational methods. Computational simulations directed at basic understanding and modelling are important tools provided by computational dosimetry, while another very important application is the support that it can give to the design, optimization and analysis of experiments. However, the primary task of computational dosimetry is to reduce the variance in the determination of absorbed dose (and its related quantities), for example in the disciplines of radiological protection and radiation therapy. In this paper emphasis is given to the discussion of potential pitfalls in the applications of computational dosimetry and recommendations are given for their avoidance. The need for comparison of calculated and experimental data whenever possible is strongly stressed.

  14. Internal dosimetry, past and future

    International Nuclear Information System (INIS)

    This paper is a review of the progress in the dosimetry of internally deposited radionuclides (internal dosimetry) since World War II. Previous to that, only naturally occurring radionuclides were available and only a limited number of studies of biokinetics and dosimetry were done. The main radionuclides studied were 226Ra, 228Ra, and 224Ra but natural uranium was also studied mainly because of its toxic effect as a heavy metal, and not because it was radioactive. The effects of 226Ra in bone, mainly from the radium dial painters, also formed the only bases for the radiotoxicity of radionuclides in bone for many years, and it is still, along with 224Ra, the main source of information on the effects of alpha emitters in bone. The publications of the International Commission on Radiological Protection that have an impact on internal dosimetry are used as mileposts for this review. These series of publications, more than any other, represent a broad consensus of opinion within the radiation protection community at the time of their publication, and have formed the bases for radiation protection practice throughout the world. This review is not meant to be exhaustive; it is meant to be a personnel view of the evolution of internal dosimetry, and to present the author's opinion of what the future directions in internal dosimetry will be. 39 refs., 2 tabs

  15. Genetic stability of the VHSV consensus sequence of G-gene in diagnostic samples from an acute outbreak

    DEFF Research Database (Denmark)

    Einer-Jensen, Katja; Ahrens, Peter; Lorenzen, Niels

    2006-01-01

    collected tissue material as well as from inoculated cell culture. No nucleotide substitutions where identified when aligning the obtained sequence data for the two sample types. The presented data indicate that the overall consensus sequence of the virus outbreak was stable during the survey......The negative stranded RNA virus viral haemorrhagic septicaemia virus (VHSV) is an important disease-causing agent in aquacultured fish and internationally harmonized diagnostic procedures are continuously under development. The present study concerns the suitability of genotyping by sequencing...... and the initial diagnosis was based on isolation of the virus by cell cultivation and subsequent identification by ELISA. Additional tissue samples were collected 25 days after the initial sampling. RT-PCR amplification and sequencing of the entire glycoprotein-gene (1524 nt) was performed on RNA purified from...

  16. Recommendations on pre-hospital & early hospital management of acute heart failure : a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine

    NARCIS (Netherlands)

    Mebazaa, Alexandre; Yilmaz, M. Birhan; Levy, Phillip; Ponikowski, Piotr; Peacock, W. Frank; Laribi, Said; Ristic, Arsen D.; Lambrinou, Ekaterini; Masip, Josep; Riley, Jillian P.; McDonagh, Theresa; Mueller, Christian; deFilippi, Christopher; Harjola, Veli-Pekka; Thiele, Holger; Piepoli, Massimo F.; Metra, Marco; Maggioni, Aldo; McMurray, John; Dickstein, Kenneth; Damman, Kevin; Seferovic, Petar M.; Ruschitzka, Frank; Leite-Moreira, Adelino F.; Bellou, Abdelouahab; Anker, Stefan D.; Filippatos, Gerasimos

    2015-01-01

    Acute heart failure is a fatal syndrome. Emergency physicians, cardiologists, intensivists, nurses and other health care providers have to cooperate to provide optimal benefit. However, many treatment decisions are opinion-based and few are evidenced-based. This consensus paper provides guidance to

  17. Dosimetry in diagnostic radiology

    International Nuclear Information System (INIS)

    Dosimetry is an area of increasing importance in diagnostic radiology. There is a realisation amongst health professionals that the radiation dose received by patients from modern X-ray examinations and procedures can be at a level of significance for the induction of cancer across a population, and in some unfortunate instances, in the acute damage to particular body organs such as skin and eyes. The formulation and measurement procedures for diagnostic radiology dosimetry have recently been standardised through an international code of practice which describes the methodologies necessary to address the diverging imaging modalities used in diagnostic radiology. Common to all dosimetry methodologies is the measurement of the air kerma from the X-ray device under defined conditions. To ensure the accuracy of the dosimetric determination, such measurements need to be made with appropriate instrumentation that has a calibration that is traceable to a standards laboratory. Dosimetric methods are used in radiology departments for a variety of purposes including the determination of patient dose levels to allow examinations to be optimized and to assist in decisions on the justification of examination choices. Patient dosimetry is important for special cases such as for X-ray examinations of children and pregnant patients. It is also a key component of the quality control of X-ray equipment and procedures.

  18. Dosimetry in diagnostic radiology.

    Science.gov (United States)

    Meghzifene, Ahmed; Dance, David R; McLean, Donald; Kramer, Hans-Michael

    2010-10-01

    Dosimetry is an area of increasing importance in diagnostic radiology. There is a realisation amongst health professionals that the radiation dose received by patients from modern X-ray examinations and procedures can be at a level of significance for the induction of cancer across a population, and in some unfortunate instances, in the acute damage to particular body organs such as skin and eyes. The formulation and measurement procedures for diagnostic radiology dosimetry have recently been standardised through an international code of practice which describes the methodologies necessary to address the diverging imaging modalities used in diagnostic radiology. Common to all dosimetry methodologies is the measurement of the air kerma from the X-ray device under defined conditions. To ensure the accuracy of the dosimetric determination, such measurements need to be made with appropriate instrumentation that has a calibration that is traceable to a standards laboratory. Dosimetric methods are used in radiology departments for a variety of purposes including the determination of patient dose levels to allow examinations to be optimized and to assist in decisions on the justification of examination choices. Patient dosimetry is important for special cases such as for X-ray examinations of children and pregnant patients. It is also a key component of the quality control of X-ray equipment and procedures. PMID:20655679

  19. Dosimetry Service

    CERN Multimedia

    Dosimetry Service

    2005-01-01

    Please remember to read your dosimeter at least once every month. A regular read-out is indispensable to ensure periodic monitoring of your personal dose. You must read your dosimeter even if you have not visited the controlled areas. Film badges are no longer valid at CERN and holders of film badges are no longer allowed to enter the controlled radiation areas or work with a source. Dosimetry Service Tel. 72155 http://cern.ch/rp-dosimetry

  20. Dosimetry methods

    DEFF Research Database (Denmark)

    McLaughlin, W.L.; Miller, A.; Kovacs, A.;

    2003-01-01

    Chemical and physical radiation dosimetry methods, used for the measurement of absorbed dose mainly during the practical use of ionizing radiation, are discussed with respect to their characteristics and fields of application.......Chemical and physical radiation dosimetry methods, used for the measurement of absorbed dose mainly during the practical use of ionizing radiation, are discussed with respect to their characteristics and fields of application....

  1. Current treatment and future prospects for the management of acute coronary syndromes: consensus recommendations of the 1997 ushuaia conference, tierra del fuego, Argentina.

    Science.gov (United States)

    Gurfinkel, E

    1998-01-01

    Management of acute coronary syndromes, particularly unstable angina, acute myocardial infarction and non-Q-wave myocardial infarction, is one of the most common and costly problems facing modern medicine. Furthermore, the increasing availability of new research and clinical information relevant to the treatment of these conditions means that continuing reappraisal of management strategies is necessary. Accordingly, the Ushuaia conference, Tierra Del Fuego, Argentina, was convened to discuss current approaches and future treatment prospects for patients with these conditions. The conference was comprised of leading Argentinian cardiologists whose primary aim was to formulate consensus recommendations regarding the management of patients with acute coronary syndromes. The first of the major recommendations for the pharmacological management of acute coronary syndromes arising from the Ushuaia Consensus Conference was that aspirin (200 to 500mg initially, then 100 to 325 mg/day) should be administered to all patients except those for whom aspirin is absolutely (or relatively, depending on the clinician's discretion) contraindicated. In such cases, ticlopidine is a suitable alternative. Intravenous nitrates are indicated for patients with angina pain (24 to 48 hours' duration), ECG changes, recurrence of angina, or signs of heart failure; in other cases, oral, transdermal or sublingual nitrates may be administered. Use of beta-blockers is recommended except when absolutely contraindicated or when there is a strong suspicion of vasospasm as a dominant mechanism in angina. Intravenous administration of these agents is preferred in patients with tachycardia, arterial hypertension or angina. Calcium antagonists are generally not recommended as first choice therapy, but can be indicated (preferably using agents that decrease heart rate) when beta-blockers are contraindicated or when there is a strong suspicion of vasospasm as a dominant mechanism in angina. Calcium

  2. Dosimetry standards

    International Nuclear Information System (INIS)

    The following leaflets are contained in this folder concerning the National Physical Laboratory's measurement services available in relation to dosimetry standards: Primary standards of X-ray exposure and X-ray irradiation facilities, X-ray dosimetry at therapy levels, Protection-level X-ray calibrations, Therapy-level gamma-ray facility, Fricke dosemeter reference service, Low-dose-rate gamma-ray facility, Penetrameter and kV meter calibration, Measurement services for radiation processing, Dichromate dosemeter reference service, Electron linear accelerator. (U.K.)

  3. Consensus conferences

    DEFF Research Database (Denmark)

    Nielsen, Annika Porsborg; Lassen, Jesper

    Our results point to significant national variation both in terms of the perceived aim of consensus conferences, expectations to conference outcomes, conceptions of the roles of lay people and experts, and in terms of the way in which the role of public deliberation is interpreted. Interestingly......, the differing perceptions are each in their own way rooted in an argument for democratic legitimacy. We therefore argue that national interpretations of consensus conferences, and of their ability to functions as a tool for public participation, depend to a great extent on the dominant ideals of democratic...

  4. (Biological dosimetry)

    Energy Technology Data Exchange (ETDEWEB)

    Preston, R.J.

    1990-12-17

    The traveler attended the 1st International Conference on Biological Dosimetry in Madrid, Spain. This conference was organized to provide information to a general audience of biologists, physicists, radiotherapists, industrial hygiene personnel and individuals from related fields on the current ability of cytogenetic analysis to provide estimates of radiation dose in cases of occupational or environmental exposure. There is a growing interest in Spain in biological dosimetry because of the increased use of radiation sources for medical and occupational uses, and with this the anticipated and actual increase in numbers of overexposure. The traveler delivered the introductory lecture on Biological Dosimetry: Mechanistic Concepts'' that was intended to provide a framework by which the more applied lectures could be interpreted in a mechanistic way. A second component of the trip was to provide advice with regard to several recent cases of overexposure that had been or were being assessed by the Radiopathology and Radiotherapy Department of the Hospital General Gregorio Maranon'' in Madrid. The traveler had provided information on several of these, and had analyzed cells from some exposed or purportedly exposed individuals. The members of the biological dosimetry group were referred to individuals at REACTS at Oak Ridge Associated Universities for advice on follow-up treatment.

  5. Neutron personnel dosimetry

    International Nuclear Information System (INIS)

    The current state-of-the-art in neutron personnel dosimetry is reviewed. Topics covered include dosimetry needs and alternatives, current dosimetry approaches, personnel monitoring devices, calibration strategies, and future developments

  6. Why Consensus?

    Directory of Open Access Journals (Sweden)

    Francesca Polletta

    2016-05-01

    Full Text Available Activists have long justified their egalitarian organizational forms in prefigurative terms. Making decisions by consensus, decentralizing organization, and rotating leadership serves to model the radically democratic society that activists hope to bring into being. Our comparison of consensus-based decision-making in three historical periods, however, shows that activists have understood the purposes of prefiguration in very different ways. Whereas radical pacifists in the 1940s saw their cooperative organizations as sustaining movement stalwarts in a period of political repression, new left activists in the 1960s imagined that their radically democratic practices would be adopted by ever-widening circles. Along with the political conditions in which they have operated, activists’ distinctive understandings of equality have also shaped the way they have made decisions. Our interviews with 30 leftist activists today reveal a view of decision-making as a place to work through inequalities that are informal, unacknowledged, and pervasive.

  7. Dosimetry Service

    CERN Multimedia

    Dosimetry Service

    2005-01-01

    Please remember to read your dosimeter every month at least once and preferably during the first week. A regular read-out is indispensable in order to ensure a periodic monitoring of the personal dose. You should read your dosimeter even if you have not visited the controlled areas. If you still have the old dosimeter (film badge), please send it immediately for evaluation to us (Bdg 24 E-011). After January 2005 there will be no developing process for the old film system. Information for Contractors: Please remember also to bring the form ‘Confirm Reception of a CERN Dosimeter' signed with ‘Feuille d'enregistrement du CERN'. Without these forms the dosimeter cannot be assigned. Thank you for your cooperation. Dosimetry Service Tel 767 2155 http://cern.ch/rp-dosimetry

  8. Phototherapy with low intensity laser in carrageenan-induced acute inflammatory process in mice paw - dosimetry studies

    International Nuclear Information System (INIS)

    The importance of modulation of inflammation on the treatment of inflammatory diseases and the difficulty in determining the laser irradiation parameters has led us to study the effects of different protocols of phototherapy with low intensity laser (power, energy, time and place of irradiation) in the treatment and prevention of edema in acute inflammatory process using the experimental model of paw edema induced by carrageenan (CGN) in three strains of mice (Balb-c, Swiss and C57BL/6). The first stage of the study evaluated different combinations of energy (1J and 3J) with different powers (30, 60 and 100mW) in Balb-C mice paw irradiated 1 and 2h after injection of CGN. The second stage studied different combinations of location (foot, inguinal lymph nodes and both) and exposure time (2 and 1h before, 1h and immediately before the CGN, 1 and 2h and 3.5 and 4.5h after CGN) using fixed irradiation parameters (1J, 100mW, 35J/cm2, spot area of 0.028 cm2). The third stage compared different strains of mice Balb-c and C57BL/6) in the best local and time parameters found in step 2. At all stages, we evaluated the change in paw volume by plethysmography and inflammatory infiltrate by histomorphometry or analysis of myeloperoxidase (MPO). The results showed that laser phototherapy treated and prevented edema and modulated the inflammatory process with paw and inguinal lymph nodes irradiations accordingly with the parameters and mice strain used. (author)

  9. Topics in radiation dosimetry radiation dosimetry

    CERN Document Server

    1972-01-01

    Radiation Dosimetry, Supplement 1: Topics in Radiation Dosimetry covers instruments and techniques in dealing with special dosimetry problems. The book discusses thermoluminescence dosimetry in archeological dating; dosimetric applications of track etching; vacuum chambers of radiation measurement. The text also describes wall-less detectors in microdosimetry; dosimetry of low-energy X-rays; and the theory and general applicability of the gamma-ray theory of track effects to various systems. Dose equivalent determinations in neutron fields by means of moderator techniques; as well as developm

  10. Dosimetry for radiation processing

    DEFF Research Database (Denmark)

    Miller, Arne

    1986-01-01

    During the past few years significant advances have taken place in the different areas of dosimetry for radiation processing, mainly stimulated by the increased interest in radiation for food preservation, plastic processing and sterilization of medical products. Reference services both...... and sterilization dosimetry, optichromic dosimeters in the shape of small tubes for food processing, and ESR spectroscopy of alanine for reference dosimetry. In this paper the special features of radiation processing dosimetry are discussed, several commonly used dosimeters are reviewed, and factors leading...

  11. Neutron dosimetry - A review

    International Nuclear Information System (INIS)

    This review summarizes information on the following subjects: (1) physical processes of importance in neutron dosimetry; (2) biological effects of neutrons; (3) neutron sources; and (4) instruments and methods used in neutron dosimetry. Also, possible improvements in dosimetry instrumentation are outlined and discussed. (author)

  12. Dosimetry in intravascular brachytherapy

    International Nuclear Information System (INIS)

    Among the cardiovascular diseases responsible for deaths in the adult population in almost all countries of the world, the most common is acute myocardial infarction, which generally occurs because of the occlusion of one or more coronary arteries. Several diagnostic techniques and therapies are being tested for the treatment of coronary artery disease. Balloon angioplasty has been a popular treatment which is less invasive than traditional surgeries involving revascularization of the myocardium, thus promising a better quality of life for patients. Unfortunately, the rate of restenosis (re-closing of the vessel) after balloon angioplasty is high (approximately 30-50% within the first year after treatment).Recently, the idea of delivering high radiation doses to coronary arteries to avoid or delay restenosis has been suggested. Known as intravascular brachytherapy, the technique has been used with several radiation sources, and researchers have obtained success in decreasing the rate of restenosis in some patient populations. In order to study the radiation dosimetry in the patient and radiological protection for the attending staff for this therapy, radiation dose distributions for monoenergetic electrons and photons (at nine discrete energies) were calculated for blood vessels of diameter 0.15, o,30 and 0.45 cm with balloon and wire sources using the radiation transport code MCNP4B. Specific calculations were carried out for several candidate radionuclides as well. Two s tent sources (metallic prosthesis that put inside of patient's artery through angioplasty) employing 32 P are also simulated. Advantages and disadvantages of the various radionuclides and source geometries are discussed. The dosimetry developed here will aid in the realization of the benefits obtained in patients for this promising new technology. (author)

  13. The Vinca dosimetry experiment

    International Nuclear Information System (INIS)

    On 15 October 1958 there occurred a very brief uncontrolled run of the zero-power reactor at the Boris Kidric Institute of Nuclear Science, Vinca, near Belgrade, Yugoslavia. During this run six persons received various doses of radiation. They were subsequently given medical treatment of a novel kind at the Curie Hospital, Paris. In atomic energy operations to date, very few accidents involving excessive radiation exposure to human beings have occurred. In fact, the cases of acute radiation injury are limited to about 30 known high exposures, few of which were in the lethal or near-lethal range. Since direct experiment to determine the effects of ionizing radiation on man is unacceptable, information on these effects has to be based on a consideration of data relating to accidental exposures, viewed in the light of the much more extensive data obtained from experiments on animals. Therefore, any direct information on the effects of radiation on humans is very valuable. The international dosimetry project described in this report was carried out at Vinca, Yugoslavia, under the auspices of the International Atomic Energy Agency to determine the precise amount of radiation to which the persons had been exposed during the accident. These dosimetry data, together with the record of the carefully observed clinical effects, are of importance both for the scientific study of radiation effects on man and for the development of methods of therapy. The experiment and measurements were carried out at the end of April 1960. The project formed part of the Agency's research programme in the field of health and safety. The results of the experiment are made available through this report to all Member States

  14. Dosimetry of total body irradiation

    International Nuclear Information System (INIS)

    In the treatment of disseminated malignancies an improvement in the curability and reduction of complication rates require high precision total body irradiation (TBI) and correct reporting of relevant treatment parameters. Optimal TBI dosimetry is the basis. Radiooncological and radiobiological requirements as well as the special physical situation have to be considered. To review the efforts of medical physicists, highlights from TBI workshops and publications are summarized. Additionally, dosimetric data from 34 European radiooncological centres contributing to the recent ESTRO inquiry on TBI are analysed. The topics are: absorbed dose and dose monitor calibration, determination of absolute and relative doses, dose ratios, attenuation data and heterogeneity corrections; TBI dose calculation methods regarding patient position, beam incidence, body shape and thickness, lung size and density; methods of TBI treatment planning including calculated dose modification and of TBI quality assurance. In conclusion, the following recommendations can be given: TBI dosimetry shall be performed under TBI conditions, close to the real treatment situation. The absorbed dose to water must be determined. The dose monitor should be calibrated against dose measurements at the centre of a water equivalent phantom of TBI equivalent size and typical thickness. Photon fluence profiles have to be measured with small phantoms. Influences on the local dose must be investigated systematically. A reproducible AP/PA TBI technique should be used. The TBI dose shall be specified to mid-abdomen and reported in units of gray. The single and total dose and the dose rate to the lungs, the number of fractions and the treatment time schedule must be stated. In vivo dosimetry is required if non-reliable TBI techniques are used. An international TBI dosimetry intercomparison could assist these efforts to improve the treatment of acute leukaemia. (author). 89 refs, 3 figs, 13 tabs

  15. Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric Acute Lymphocytic Leukemia (ALL): Review from an International Consensus Conference

    NARCIS (Netherlands)

    T.M. Horton (Terzah); R. Sposto (Richard); P. Brown (Patrick); C.P. Reynolds (Patrick); S.P. Hunger (Stephen); N.J. Winick (Naomi); E.A. Raetz (Elizabeth); W.L. Carroll (William); R.J. Arceci (Robert); M.J. Borowitz (Michael); P.S. Gaynon (Paul); L. Gore (Lia); S. Jeha (Sima); B.J. Maurer (Barry); S.E. Siegel (Stuart); A. Biondi (Andrea); P. Kearns (Pamela); A. Narendran (Aru); L.B. Silverman (Lewis); M.A. Smith (Malcolm); C.M. Zwaan (Michel); J.A. Whitlock (James)

    2010-01-01

    textabstractOne of the challenges of incorporating molecularly targeted drugs into multi-agent chemotherapy (backbone) regimens is defining dose-limiting toxicities (DLTs) of the targeted agent against the background of toxicities of the backbone regimen. An international panel of 22 pediatric acute

  16. Acute skin toxicity management in head and neck cancer patients treated with radiotherapy and chemotherapy or EGFR inhibitors : Literature review and consensus

    NARCIS (Netherlands)

    Russi, Elvio G.; Moretto, Francesco; Rampino, Monica; Benasso, Marco; Bacigalupo, Almalina; De Sanctis, Vitaliana; Numico, Gianrnauro; Bossi, Paolo; Buglione, Michela; Lombardo, Antonino; Airoldi, Mario; Merlano, Marco C.; Licitra, Lisa; Denaro, Nerina; Pergolizzi, Stefano; Pinto, Carmine; Bensadoun, Rene-Jean; Girolomoni, Giarnpiero; Langendijk, Johannes A.

    2015-01-01

    The adverse effects of radiation therapy, often integrated with chemotherapy and/or targeted therapies, on the skin include severe acute and chronic dermatitis associated with pain, discomfort, itching, and burning, and may heavily affect patients' quality of life. The management of these skin adver

  17. The use of the Berlin definition for acute respiratory distress syndrome during infancy and early childhood : multicenter evaluation and expert consensus

    NARCIS (Netherlands)

    De Luca, Daniele; Piastra, Marco; Chidini, Giovanna; Tissieres, Pierre; Calderini, Edoardo; Essouri, Sandrine; Medina Villanueva, Alberto; Vivanco Allende, Ana; Pons-Odena, Marti; Perez-Baena, Luis; Hermon, Michael; Tridente, Ascanio; Conti, Giorgio; Antonelli, Massimo; Kneyber, Martin

    2013-01-01

    A new acute respiratory distress syndrome (ARDS) definition has been recently issued: the so-called Berlin definition (BD) has some characteristics that could make it suitable for pediatrics. The European Society for Pediatric Neonatal Intensive Care (ESPNIC) Respiratory Section started a project to

  18. Measurement assurance in dosimetry

    International Nuclear Information System (INIS)

    The uses of radiation in medicine and industry are today wide in scope and diversity and there is a need for reliable dosimetry in most applications. In particular, high accuracy in dosimetry is required in the therapeutic use of radiation. Consequently, calibration procedures for radiotherapy generally meet also the accuracy requirements for applications in other fields, such as diagnostic radiology, radiation protection and industrial radiation processing. The emphasis at this symposium was therefore mainly or radiotherapy dosimetry, but the meeting also included one session devoted to dosimetry in diagnostic radiology. Refs, fig and tabs

  19. The role of the ECG in diagnosis, risk estimation, and catheterization laboratory activation in patients with acute coronary syndromes: a consensus document.

    Science.gov (United States)

    Birnbaum, Yochai; Nikus, Kjell; Kligfield, Paul; Fiol, Miguel; Barrabés, Jose Antonio; Sionis, Alessandro; Pahlm, Olle; Niebla, J Garcia; de Luna, Antonio Bayès

    2014-09-01

    The electrocardiogram (ECG) is the most widely used imaging tool helping in diagnosis and initial management of patients presenting with symptoms compatible with acute coronary syndrome. Acute ischemia affects the configuration of the QRS complexes, the ST segments and the T waves. The ECG should be read along with the clinical assessment of the patient. ST segment elevation (and ST depression in leads V1 -V3 ) in patients with active symptoms usually indicates acute occlusion of an epicardial artery with ongoing transmural ischemia. These patients should be triaged for emergent reperfusion therapy per current guidelines. However, many patients have ST segment elevation secondary to nonischemic causes. ST depression in leads other than V1 -V3 usually are indicative of subendocardial ischemia secondary to subocclusion of the epicardial artery, distal embolization to small arteries or spasm supply/demand mismatch. ST depression may also be secondary to nonischemic etiologies, such as left ventricular hypertrophy, cardiomyopathies, etc. Knowing the clinical scenario, comparison to previous ECG and subsequent ECGs (in cases that there are changes in the quality or severity of symptoms) may add in the diagnosis and interpretation in difficult cases. This review addresses the different ECG patterns, typically seen in patients with active symptoms, after resolution of symptoms and the significance of such changes when seen in asymptomatic patients.

  20. Dosimetry service removal

    CERN Multimedia

    Safety Commission

    2010-01-01

    Dear personal dosimeter user, Please note that the Dosimetry service has moved in building 55, the service is now located in the main floor: 55-R-004. Main floor instead of second floor. On your right hand when accessing in the building. Thank you Dosimetry Service

  1. Dosimetry in process control

    International Nuclear Information System (INIS)

    Measurement of absorbed dose and dose distribution in irradiated medical products relies on the use of quality dosimetry systems, trained personnel and a thorough understanding of the energy deposition process. The interrelationship of these factors will be discussed with emphasis on the current and future practices of process control dosimetry. (author)

  2. 2016 updated MASCC/ESMO consensus recommendations

    DEFF Research Database (Denmark)

    Roila, Fausto; Warr, David; Hesketh, Paul J;

    2016-01-01

    PURPOSE: An update of the recommendations for the prophylaxis of acute and delayed emesis induced by moderately emetogenic chemotherapy published after the last MASCC/ESMO antiemetic consensus conference in 2009 has been carried out. METHODS: A systematic literature search using PubMed from Janua...

  3. Consensus Sequence Zen

    OpenAIRE

    Schneider, Thomas D.

    2002-01-01

    Consensus sequences are widely used in molecular biology but they have many flaws. As a result, binding sites of proteins and other molecules are missed during studies of genetic sequences and important biological effects cannot be seen. Information theory provides a mathematically robust way to avoid consensus sequences. Instead of using consensus sequences, sequence conservation can be quantitatively presented in bits of information by using sequence logo graphics to repre...

  4. The Limits of Consensus.

    Science.gov (United States)

    Poster, John B.

    Dynamics in the education policy arena suggest that, despite two generations of researchers extolling democratic leadership styles and consensus building over autocratic techniques, wide participation in policymaking and the broadest possible consensus are not always productive: American society has not yet agreed on what schools should…

  5. Model-based consensus

    NARCIS (Netherlands)

    M. Boumans

    2014-01-01

    The aim of the rational-consensus method is to produce "rational consensus", that is, "mathematical aggregation", by weighing the performance of each expert on the basis of his or her knowledge and ability to judge relevant uncertainties. The measurement of the performance of the experts is based on

  6. Consensus statement from the 2014 International Microdialysis Forum

    DEFF Research Database (Denmark)

    Hutchinson, Peter J; Jalloh, Ibrahim; Helmy, Adel;

    2015-01-01

    Microdialysis enables the chemistry of the extracellular interstitial space to be monitored. Use of this technique in patients with acute brain injury has increased our understanding of the pathophysiology of several acute neurological disorders. In 2004, a consensus document on the clinical appl...

  7. Nuclear medicine radiation dosimetry

    CERN Document Server

    McParland, Brian J

    2010-01-01

    Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and

  8. INDIVIDUAL DOSIMETRY SERVICE

    CERN Multimedia

    2000-01-01

    Personnel in the distribution groups Aleph, Delphi, L3, Opal who also work for other experiments than at LEP, should contact their dispatchers to explain their activities for the future, after LEP dismantling in order to be maintained on the regular distribution list at Individual DosimetryWe inform all staff and users under regular dosimetric control that the dosimeters for the monitoring period MAY/JUNE will be available from their usual dispatchers on Tuesday 2 May.Please have your films changed before the 12 May.The colour of the dosimeter valid in is MAY/JUNE is YELLOW.Individual Dosimetry Service will be closed on Friday 28 April.

  9. Practical Techniques for Achieving Consensus.

    Science.gov (United States)

    Kline, John A.

    Consensus is important in the making of a policy decision. If a decision is reached without consensus, morale and unit satisfaction may both suffer. With genuine consensus, a unit tends to willingly support and implement the new policy. After analyzing how observed small groups had actually reached consensus, the following ten techniques were…

  10. Status of radiation processing dosimetry

    DEFF Research Database (Denmark)

    Miller, A.

    1993-01-01

    Several milestones have marked the field of radiation processing dosimetry since IMRP 7. Among them are the IAEA symposium on High Dose Dosimetry for Radiation Processing and the international Workshops on Dosimetry for Radiation Processing organized by the ASTM. Several standards have been...... or are being published by the ASTM in this field, both on dosimetry procedures and on the proper use of specific dosimeter systems. Several individuals are involved in this international cooperation which contribute significantly to the broader understanding of the role of dosimetry in radiation processing....... The importance of dosimetry is emphasized in the standards on radiation sterilization which are currently drafted by the European standards organization CEN and by the international standards organization ISO. In both standards, dosimetry plays key roles in characterization of the facility, in qualification...

  11. Early management of patients with acute heart failure: state of the art and future directions. A consensus document from the society for academic emergency medicine/heart failure society of America acute heart failure working group.

    Science.gov (United States)

    Collins, Sean; Storrow, Alan B; Albert, Nancy M; Butler, Javed; Ezekowitz, Justin; Felker, G Michael; Fermann, Gregory J; Fonarow, Gregg C; Givertz, Michael M; Hiestand, Brian; Hollander, Judd E; Lanfear, David E; Levy, Phillip D; Pang, Peter S; Peacock, W Frank; Sawyer, Douglas B; Teerlink, John R; Lenihan, Daniel J

    2015-01-01

    Heart failure (HF) afflicts nearly 6 million Americans, resulting in one million emergency department (ED) visits and over one million annual hospital discharges. An aging population and improved survival from cardiovascular diseases is expected to further increase HF prevalence. Emergency providers play a significant role in the management of patients with acute heart failure (AHF). It is crucial that emergency physicians and other providers involved in early management understand the latest developments in diagnostic testing, therapeutics and alternatives to hospitalization. Further, clinical trials must be conducted in the ED in order to improve the evidence base and drive optimal initial therapy for AHF. Should ongoing and future studies suggest early phenotype-driven therapy improves in-hospital and post-discharge outcomes, ED treatment decisions will need to evolve accordingly. The potential impact of future studies which incorporate risk-stratification into ED disposition decisions cannot be underestimated. Predictive instruments that identify a cohort of patients safe for ED discharge, while simultaneously addressing barriers to successful outpatient management, have the potential to significantly impact quality of life and resource expenditures.

  12. Ion storage dosimetry

    Science.gov (United States)

    Mathur, V. K.

    2001-09-01

    The availability of a reliable, accurate and cost-effective real-time personnel dosimetry system is fascinating to radiation workers. Electronic dosimeters are contemplated to meet this demand of active dosimetry. The development of direct ion storage (DIS) dosimeters, a member of the electronic dosimeter family, for personnel dosimetry is also an attempt in this direction. DIS dosimeter is a hybrid of the well-established technology of ion chambers and the latest advances in data storage using metal oxide semiconductor field effect transistor (MOSFET) analog memory device. This dosimeter is capable of monitoring legal occupational radiation doses of gamma, X-rays, beta and neutron radiation. Similar to an ion chamber, the performance of the dosimeter for a particular application can be optimized through the selection of appropriate wall materials. The use of the floating gate of a MOSFET as one of the electrodes of the ion chamber allows the miniaturization of the device to the size of a dosimetry badge and avoids the use of power supplies during dose accumulation. The concept of the device, underlying physics and the design of the DIS dosimeter are discussed. The results of preliminary testing of the device are also provided.

  13. Dosimetry and Calibration Section

    International Nuclear Information System (INIS)

    The two tasks of the Dosimetry and Calibration Section at CERN are the Individual Dosimetry Service which assures the personal monitoring of about 5000 persons potentially exposed to ionizing radiation at CERN, and the Calibration Laboratory which verifies all the instruments and monitors. This equipment is used by the sections of the RP Group for assuring radiation protection around CERN's accelerators, and by the Environmental Section of TISTE. In addition, nearly 250 electronic and 300 quartz fibre dosimeters, employed in operational dosimetry, are calibrated at least once a year. The Individual Dosimetry Service uses an extended database (INDOS) which contains information about all the individual doses ever received at CERN. For most of 1997 it was operated without the support of a database administrator as the technician who had assured this work retired. The Software Support Section of TIS-TE took over the technical responsibility of the database, but in view of the many other tasks of this Section and the lack of personnel, only a few interventions for solving immediate problems were possible

  14. High frequency electromagnetic dosimetry

    CERN Document Server

    Sánchez-Hernández, David A

    2009-01-01

    Along with the growth of RF and microwave technology applications, there is a mounting concern about the possible adverse effects over human health from electromagnetic radiation. Addressing this issue and putting it into perspective, this groundbreaking resource provides critical details on the latest advances in high frequency electromagnetic dosimetry.

  15. Continuity and consensus

    DEFF Research Database (Denmark)

    Abrahamson, Peter

    2010-01-01

    maternal leave. These changes can be explained as adjustments to post-industrial conditions within a political culture relying on class compromises and a broad consensus informed by expert advice coming from civil servants and ad hoc policy commissions. The paper concludes that changes in Danish family...... policy reflect changing conditions for employment and the minding of children and that there has been a high degree of continuity and consensus about the change, as indicated by the strong increase in female labour market involvement....

  16. Model-based consensus

    NARCIS (Netherlands)

    Boumans, Marcel

    2014-01-01

    The aim of the rational-consensus method is to produce “rational consensus”, that is, “mathematical aggregation”, by weighing the performance of each expert on the basis of his or her knowledge and ability to judge relevant uncertainties. The measurement of the performance of the experts is based on

  17. Critique, Contextualism and Consensus

    Science.gov (United States)

    Green, Jane

    2004-01-01

    In an epistemology of contextualism, how robust does consensus need to be for critique to be practically effective? In 'Relativism and the Critical Potential of Philosophy of Education,' Frieda Heyting proposes a form of contextualism, but her argument raises a number of problems. The kinds of criteria that her version of contextualism will…

  18. Making Consensus Tractable

    CERN Document Server

    Mossel, Elchanan

    2010-01-01

    The process of consensus voting has many distinct advantages: it fosters discussion and participation, empowers minorities and independent thinkers, and is more likely, after a decision has been made, to secure the participants' support for the chosen course of action. The disadvantage of consensus decision making is, of course, the difficulty of reaching consensus. While this challenge is largely overcome in many theoretical settings such as Aumann's ``agree to disagree'' result, a hitherto unsolved difficulty is the lack of a framework offering rational (i.e., Bayesian) consensus decision making that can be performed using simple and efficient calculations. We propose a model featuring two possible states of the world and a finite number of individuals. The group has to come to a binary decision, where the merit of each of the two possible courses of action depends on the state of the world. Each member of the group has a private and independent signal at his or her disposal, giving some indication as to wh...

  19. In vivo dosimetry for IMRT

    Science.gov (United States)

    Vial, Philip

    2011-05-01

    In vivo dosimetry has a well established role in the quality assurance of 2D radiotherapy and 3D conformal radiotherapy. The role of in vivo dosimetry for IMRT is not as well established. IMRT introduces a range of technical issues that complicate in vivo dosimetry. The first decade or so of IMRT implementation has largely relied upon pre-treatment phantom based dose verification. During that time, several new devices and techniques for in vivo dosimetry have emerged with the promise of providing the ultimate form of IMRT dose verification. Solid state dosimeters continue to dominate the field of in vivo dosimetry in the IMRT era. In this report we review the literature on in vivo dosimetry for IMRT, with an emphasis on clinical evidence for different detector types. We describe the pros and cons of different detectors and techniques in the IMRT setting and the roles that they are likely to play in the future.

  20. The dosimetry of ionizing radiation

    CERN Document Server

    1990-01-01

    A continuation of the treatise The Dosimetry of Ionizing Radiation, Volume III builds upon the foundations of Volumes I and II and the tradition of the preceeding treatise Radiation Dosimetry. Volume III contains three comprehensive chapters on the applications of radiation dosimetry in particular research and medical settings, a chapter on unique and useful detectors, and two chapters on Monte Carlo techniques and their applications.

  1. Ambiguities in thermoluminescence dosimetry

    International Nuclear Information System (INIS)

    On one hand, thermoluminescence dosimetry is one of most reliable, rugged and economical system of passive dosimetry but on the other hand there are several ambiguities, which need attention. The PTTL is a complex phenomenon and it is difficult to identify the source for the transfer of the charge carrier to repopulate the traps related to the glow peaks. For the photon energy dependence it is difficult to explain the change in the response for 662 keV gamma rays of 137Cs as compared to the response for 1.25 MeV gamma rays of 60Co. The increase in the response of a TLD with increasing heating rate poses another ambiguity and so is the case with the observations of the supra linearity of different glow peaks. To over come the ambiguities, efforts have to continue to enhance the understanding and to harmonize the protocol for reliable experimental data

  2. Neutron beam measurement dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Amaro, C.R. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

    1995-11-01

    This report describes animal dosimetry studies and phantom measurements. During 1994, 12 dogs were irradiated at BMRR as part of a 4 fraction dose tolerance study. The animals were first infused with BSH and irradiated daily for 4 consecutive days. BNL irradiated 2 beagles as part of their dose tolerance study using BPA fructose. In addition, a dog at WSU was irradiated at BMRR after an infusion of BPA fructose. During 1994, the INEL BNCT dosimetry team measured neutron flux and gamma dose profiles in two phantoms exposed to the epithermal neutron beam at the BMRR. These measurements were performed as a preparatory step to the commencement of human clinical trials in progress at the BMRR.

  3. Quantitative imaging for clinical dosimetry

    Science.gov (United States)

    Bardiès, Manuel; Flux, Glenn; Lassmann, Michael; Monsieurs, Myriam; Savolainen, Sauli; Strand, Sven-Erik

    2006-12-01

    Patient-specific dosimetry in nuclear medicine is now a legal requirement in many countries throughout the EU for targeted radionuclide therapy (TRT) applications. In order to achieve that goal, an increased level of accuracy in dosimetry procedures is needed. Current research in nuclear medicine dosimetry should not only aim at developing new methods to assess the delivered radiation absorbed dose at the patient level, but also to ensure that the proposed methods can be put into practice in a sufficient number of institutions. A unified dosimetry methodology is required for making clinical outcome comparisons possible.

  4. Sixth symposium on neutron dosimetry

    International Nuclear Information System (INIS)

    This booklet contains all abstracts of papers presented in 13 sessions. Main topics: Cross sections and Kerma factors; analytical radiobiology; detectors for personnel monitoring; secondary charged particles and microdosimetric basis of q-value for neutrons; personnel dosimetry; concepts for radiation protection; ambient monitoring; TEPC and ion chambers in radiation protection; beam dosimetry; track detectors (CR-39); dosimetry at biomedical irradiation facilities; health physics at therapy facilities; calibration for radiation protection; devices for beam dosimetry (TLD and miscellaneous); therapy and biomedical irradiation facilities; treatment planning. (HP)

  5. Personnel radiation dosimetry

    International Nuclear Information System (INIS)

    The book contains the 21 technical papers presented at the Technical Committee Meeting to Elaborate Procedures and Data for the Intercomparison of Personnel Dosimeters organizaed by the IAEA on 22-26 April 1985. A separate abstract was prepared for each of these papers. A list of areas in which additional research and development work is needed and recommendations for an IAEA-sponsored intercomparison program on personnel dosimetry is also included

  6. INDIVIDUAL DOSIMETRY SERVICE

    CERN Multimedia

    1999-01-01

    Personnel in the distribution groups Aleph, Delphi, L3, Opal who also work for other experiments than at LEP, should contact the Individual Dosimetry ServiceWe inform all staff and users under regular dosimetric control that the dosimeters for the monitoring period JANUARY/FEBRUARY will be available from their usual dispatchers on Monday the third of January 2000.Please have your films changed:before the 12 January.The colour of the dosimeter valid in JANUARY/FEBRUARY is WHITE.

  7. INDIVIDUAL DOSIMETRY SERVICE

    CERN Multimedia

    2000-01-01

    Personnel in the distribution groups Aleph, Delphi, L3, Opal who also work for other experiments than at LEP, should contact the Individual Dosimetry Service.We inform all staff and users under regular dosimetric control that the dosimeters for the monitoring period MARCH/APRIL will be available from their usual dispatchers on the third of March 2000.Please have your films changed before the 13th of March.The colour of the dosimeter valid in MARCH/APRIL is BLUE.

  8. Personal radon daughter dosimetry

    International Nuclear Information System (INIS)

    The conventional means of radon daughter exposure estimatikn for uranium miners in Canada is by grab sampling and time weighting. Personal dosimetry is a possible alternative method with its own advantages and limitations. The author poses basic questions with regard to two methods of radon daughter detection, thermoluminescent chips and track-etch film. An historical review of previous and current research and development programs in Canada and in other countries is presented, as are brief results and conclusions of each dosimeter evaluation

  9. Dosimetry: an ARDENT topic

    CERN Multimedia

    CERN Bulletin

    2012-01-01

    The first annual ARDENT workshop took place in Vienna from 20 to 23 November. The workshop gathered together the Early-Stage Researchers (ESR) and their supervisors, plus other people involved from all the participating institutions.   “The meeting, which was organised with the local support of the Austrian Institute of Technology, was a nice opportunity for the ESRs to get together, meet each other, and present their research plans and some preliminary results of their work,” says Marco Silari, a member of CERN Radiation Protection Group and the scientist in charge of the programme. Two full days were devoted to a training course on radiation dosimetry, delivered by renowned experts. The workshop closed with a half-day visit to the MedAustron facility in Wiener Neustadt. ARDENT (Advanced Radiation Dosimetry European Network Training) is a Marie Curie ITN project funded under EU FP7 with €4 million. The project focuses on radiation dosimetry exploiting se...

  10. Achieving diagnosis by consensus

    LENUS (Irish Health Repository)

    Kane, Bridget

    2009-08-01

    This paper provides an analysis of the collaborative work conducted at a multidisciplinary medical team meeting, where a patient’s definitive diagnosis is agreed, by consensus. The features that distinguish this process of diagnostic work by consensus are examined in depth. The current use of technology to support this collaborative activity is described, and experienced deficiencies are identified. Emphasis is placed on the visual and perceptual difficulty for individual specialities in making interpretations, and on how, through collaboration in discussion, definitive diagnosis is actually achieved. The challenge for providing adequate support for the multidisciplinary team at their meeting is outlined, given the multifaceted nature of the setting, i.e. patient management, educational, organizational and social functions, that need to be satisfied.

  11. Overlapping Consensus in Malaysia

    OpenAIRE

    Monsen, Mats

    2007-01-01

    An empirical study of how Malaysian pluralism is understood through Islam Hadhari, Article 11 and the Inter-faith Commission against the backdrop of current Malaysian political and social history, coupled with a theoretical analysis through John Rawls' Political Liberalism, with particular emphasis on the idea of Overlapping Consensus. The thesis is an attempt at applying Rawls' theory on the practical case of Malaysia, as a plural society, while at the same time using the practical case of M...

  12. Note on level r consensus

    OpenAIRE

    Poliakov, Nikolay L.

    2016-01-01

    We show that the hierarchy of level $r$ consensus partially collapses. In particular, any profile $\\pi\\in \\mathcal{P}$ that exhibits consensus of level $(K-1)!$ around $\\succ_0$ in fact exhibits consensus of level $1$ around $\\succ_0$.

  13. Spanish Consensus Statement

    Science.gov (United States)

    Rey, Guillermo Álvarez; Cuesta, Jordi Ardevol; Loureda, Rafael Arriaza; España, Fernando Ávila; Matas, Ramón Balius; Pazos, Fernando Baró; de Dios Beas Jiménez, Juan; Rosell, Jorge Candel; Fernandez, César Cobián; Ros, Francisco Esparza; Colmenero, Josefina Espejo; de Prado, Jorge Fernández; Cota, Juan José García; González, Jose Ignacio Garrido; Santander, Manuela González; Munilla, Miguel Ángel Herrador; Ruiz, Francisco Ivorra; Díaz, Fernando Jiménez; Marqueta, Pedro Manonelles; Fernandez, Antonio Maestro; Benito, Juan José Muñoz; Vilás, Ramón Olivé; Teres, Xavier Peirau; Amaro, José Peña; Roque, Juan Pérez San; Parenteu, Christophe Ramírez; Serna, Juan Ribas; Álvarez, Mikel Sánchez; Marchori, Carlos Sanchez; Soto, Miguel del Valle; Alonso, José María Villalón; García, Pedro Guillen; de la Iglesia, Nicolas Hugo; Alcorocho, Juan Manuel Lopez

    2016-01-01

    On the 21st of March, 2015, experts met at Clínica CEMTRO in Madrid, Spain, under the patronage of The Spanish Society for Sports Traumatology (SETRADE), The Spanish Federation of Sports Medicine (FEMEDE), The Spanish Association of Medical Services for Football Clubs (AEMEF), and The Spanish Association of Medical Services for Basketball Clubs (AEMB) with the aim of establishing a round table that would allow specialists to consider the most appropriate current general actions to be taken when treating muscle tears in sport, based on proven scientific data described in the medical literature. Each expert received a questionnaire prior to the aforementioned meeting comprising a set of questions concerning therapeutic indications generally applied in the different stages present during muscle repair. The present Consensus Document is the result of the answers to the questionnaire and resulting discussion and consensus over which are the best current indications in the treatment of muscle tears in sport. Avoiding immobilization, not taking nonsteroidal anti-inflammatory drugs (NSAIDs) randomly, fostering early mobilization, increasing vascularization of injured, site and regulating inflammatory mechanisms—without inhibiting these from the early stages of the recovery period—all stood out as main points of the Consensus Document. Additionally, there is controversy concerning cell stimulation techniques and the use of growth factors or cell inhibitors. The decision concerning discharge was unanimous, as was the criteria considered when it came to performing sport techniques without pain. PMID:27213161

  14. Achieving consensus in environmental programs

    International Nuclear Information System (INIS)

    In this paper, the authors describe a research effort on consensus tied to the Environmental Restoration Program (ERP) within the U.S. Department of Energy's Office of Defense Waste and Transportation Management (DWTM). They define consensus and explain why consensus decisions are not merely desirable but necessary in furthering ERP activities. As examples of their planned applied research, the authors first discuss nominal group technique as a representative consensus-generating tool, and conclude by describing the consensus-related mission of the Waste Management Review Group, established to conduct independent, third-party review of DWTM/ERP plans and activities

  15. Achieving consensus in environmental programs

    Energy Technology Data Exchange (ETDEWEB)

    Kurstedt, Jr., H. A.; Jones, R. M.; Walker, J. A.; Middleman, L. I.

    1989-01-01

    In this paper, we describe a new research effort on consensus tied to the Environmental Restoration Program (ERP) within the US Department of Energy's Office of Defense Waste and Transportation Management (DWTM). We define consensus and explain why consensus decisions are not merely desirable but necessary in furthering ERP activities. As examples of our planned applied research, we first discuss Nominal Group Technique as a representative consensus-generating tool, and we conclude by describing the consensus-related mission of the Waste Management Review Group, established at Virginia Tech to conduct independent, third-party review of DWTM/ERP plans and activities. 10 refs.

  16. Microscopic enteritis: Bucharest consensus.

    Science.gov (United States)

    Rostami, Kamran; Aldulaimi, David; Holmes, Geoffrey; Johnson, Matt W; Robert, Marie; Srivastava, Amitabh; Fléjou, Jean-François; Sanders, David S; Volta, Umberto; Derakhshan, Mohammad H; Going, James J; Becheanu, Gabriel; Catassi, Carlo; Danciu, Mihai; Materacki, Luke; Ghafarzadegan, Kamran; Ishaq, Sauid; Rostami-Nejad, Mohammad; Peña, A Salvador; Bassotti, Gabrio; Marsh, Michael N; Villanacci, Vincenzo

    2015-03-01

    Microscopic enteritis (ME) is an inflammatory condition of the small bowel that leads to gastrointestinal symptoms, nutrient and micronutrient deficiency. It is characterised by microscopic or sub-microscopic abnormalities such as microvillus changes and enterocytic alterations in the absence of definite macroscopic changes using standard modern endoscopy. This work recognises a need to characterize disorders with microscopic and submicroscopic features, currently regarded as functional or non-specific entities, to obtain further understanding of their clinical relevance. The consensus working party reviewed statements about the aetiology, diagnosis and symptoms associated with ME and proposes an algorithm for its investigation and treatment. Following the 5(th) International Course in Digestive Pathology in Bucharest in November 2012, an international group of 21 interested pathologists and gastroenterologists formed a working party with a view to formulating a consensus statement on ME. A five-step agreement scale (from strong agreement to strong disagreement) was used to score 21 statements, independently. There was strong agreement on all statements about ME histology (95%-100%). Statements concerning diagnosis achieved 85% to 100% agreement. A statement on the management of ME elicited agreement from the lowest rate (60%) up to 100%. The remaining two categories showed general agreement between experts on clinical presentation (75%-95%) and pathogenesis (80%-90%) of ME. There was strong agreement on the histological definition of ME. Weaker agreement on management indicates a need for further investigations, better definitions and clinical trials to produce quality guidelines for management. This ME consensus is a step toward greater recognition of a significant entity affecting symptomatic patients previously labelled as non-specific or functional enteropathy.

  17. Fast neutron dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    DeLuca, P.M. Jr.; Pearson, D.W.

    1992-01-01

    This progress report concentrates on two major areas of dosimetry research: measurement of fast neutron kerma factors for several elements for monochromatic and white spectrum neutron fields and determination of the response of thermoluminescent phosphors to various ultra-soft X-ray energies and beta-rays. Dr. Zhixin Zhou from the Shanghai Institute of Radiation Medicine, People's Republic of China brought with him special expertise in the fabrication and use of ultra-thin TLD materials. Such materials are not available in the USA. The rather unique properties of these materials were investigated during this grant period.

  18. INDIVIDUAL DOSIMETRY SERVICE

    CERN Multimedia

    2000-01-01

    Personnel in the distribution groups Aleph, Delphi, L3, Opal who also work for other experiments than at LEP, should contact their dispatchers to explain their activities for the future, after LEP dismantling in order to be maintained on the regular distribution list at Individual Dosimetry ServiceWe inform all staffs and users under regular dosimetric control that the dosimeters for the monitoring period JULY/AUGUST are available from their usual dispatchers.Please have your films changed before the 10th of July.The colour of the dosimeter valid in JULY/AUGUST is PINK.

  19. Individual dosimetry and calibration

    International Nuclear Information System (INIS)

    In 1995 both the Individual Dosimetry and Calibration Sections worked under the condition of a status quo and concentrated fully on the routine part of their work. Nevertheless, the machine for printing the bar code which will be glued onto the film holder and hence identify the people when entering into high radiation areas was put into operation and most of the holders were equipped with the new identification. As far as the Calibration Section is concerned the project of the new source control system that is realized by the Technical Support Section was somewhat accelerated

  20. Internal Dosimetry. Chapter 18

    International Nuclear Information System (INIS)

    The Committee on Medical Internal Radiation Dose (MIRD) is a committee within the Society of Nuclear Medicine. The MIRD Committee was formed in 1965 with the mission to standardize internal dosimetry calculations, improve the published emission data for radionuclides and enhance the data on pharmacokinetics for radiopharmaceuticals [18.1]. A unified approach to internal dosimetry was published by the MIRD Committee in 1968, MIRD Pamphlet No. 1 [18.2], which was updated several times thereafter. Currently, the most well known version is the MIRD Primer from 1991 [18.3]. The latest publication on the formalism was published in 2009 in MIRD Pamphlet No. 21 [18.4], which provides a notation meant to bridge the differences in the formalism used by the MIRD Committee and the International Commission on Radiological Protection (ICRP) [18.5]. The formalism presented in MIRD Pamphlet No. 21 [18.4] will be used here, although some references to the quantities and parameters used in the MIRD primer [18.3] will be made. All symbols, quantities and units are presented

  1. BRAINSTORMING: Consensus Learning in Practice

    OpenAIRE

    Plewczynski, Dariusz

    2009-01-01

    We present here an introduction to Brainstorming approach, that was recently proposed as a consensus meta-learning technique, and used in several practical applications in bioinformatics and chemoinformatics. The consensus learning denotes heterogeneous theoretical classification method, where one trains an ensemble of machine learning algorithms using different types of input training data representations. In the second step all solutions are gathered and the consensus is build between them....

  2. Information from the Dosimetry Service

    CERN Multimedia

    2006-01-01

    Please note the following opening hours of the Service: From 31st July onwards: Every morning from 8:30 to 12:00 The Service is closed in the afternoons. We should like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCTs) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats. Dosimetry Service Tel 72155 Bldg. 24 E 011 Dosimetry.service@cern.ch http://cern.ch/rp-dosimetry

  3. Political Consensus and Fiscal Outcomes

    DEFF Research Database (Denmark)

    Houlberg, Kurt; Holm Pedersen, Lene

    2015-01-01

    to analyse the association between political consensus and public expenditure growth. The results show that political consensus is positively associated with both budgeted and actual expenditure growth, but also negatively associated with budget overruns. This indicates that political consensus comes...... at a cost, while at the same time politicians may be better at sticking to budgets if political consensus exists. The analysis is based on a pooled regression analysis of the local governments in Denmark in the years 2008 and 2009 using a data set combining survey data with administrative data on the local...

  4. Surface Hopping by Consensus.

    Science.gov (United States)

    Martens, Craig C

    2016-07-01

    We present a new stochastic surface hopping method for modeling molecular dynamics with electronic transitions. The approach, consensus surface hopping (CSH), is a numerical framework for solving the semiclassical limit Liouville equation describing nuclear dynamics on coupled electronic surfaces using ensembles of trajectories. In contrast to existing techniques based on propagating independent classical trajectories that undergo stochastic hops between the electronic states, the present method determines the probabilities of transition of each trajectory collectively with input from the entire ensemble. The full coherent dynamics of the coupled system arise naturally at the ensemble level and ad hoc corrections, such as momentum rescaling to impose strict trajectory energy conservation and artificial decoherence to avoid the overcoherence of the quantum states associated with independent trajectories, are avoided. PMID:27345103

  5. Dosimetry considerations in patients with renal pathology

    International Nuclear Information System (INIS)

    Adult dosimetry is generally performed for normal individuals and these are the absorbed dose calculations sent to FDA and listed on package inserts. However, in a variety of circumstances pathophysiologic state may significantly alter the biodistribution and kinetics of a radiopharmaceutical, and radiation doses calculated for normal individuals may not be appropriate approximations for these patients. In addition, the presence of certain pathophysiologic states often guarantees that the patient will have multiple studies over a period of days, weeks, months, or years. In order to have a true appreciation for the radiation dose commitment to such patients, it is important to examine dose totals from multiple nuclear medicine studies. Dosimetry calculations will be presented for I-123, I-124, I-125, and I-131 labeled hippuran in moderate and severe ATN, acute and chronic near-total obstruction, and renal transplants. In addition, a nuclear medicine examination profile will be presented for patients receiving renal transplants. This profile was constructed by retrospectively examining the records of 20 randomly-chosen transplant patients and recording all nuclear medicine procedures performed up to July, 1985. A total of 172 studies was performed, of which 69 were Tc-99m-DTPA flows, 62 were hippurans, and 22 were indium-111-oxine-platelets. The dosimetric contribution of all studies was assessed. The importance of the hippuran component will be discussed. 8 references, 8 tables

  6. Internal dosimetry technical basis manual

    International Nuclear Information System (INIS)

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophical discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs

  7. Radioembolization Dosimetry: The Road Ahead

    Energy Technology Data Exchange (ETDEWEB)

    Smits, Maarten L. J., E-mail: m.l.j.smits-3@umcutrecht.nl; Elschot, Mattijs [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine (Netherlands); Sze, Daniel Y. [Stanford University School of Medicine, Division of Interventional Radiology (United States); Kao, Yung H. [Austin Hospital, Department of Nuclear Medicine (Australia); Nijsen, Johannes F. W. [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine (Netherlands); Iagaru, Andre H. [Stanford University School of Medicine, Division of Nuclear Medicine and Molecular Imaging (United States); Jong, Hugo W. A. M. de; Bosch, Maurice A. A. J. van den; Lam, Marnix G. E. H. [University Medical Center Utrecht, Department of Radiology and Nuclear Medicine (Netherlands)

    2015-04-15

    Methods for calculating the activity to be administered during yttrium-90 radioembolization (RE) are largely based on empirical toxicity and efficacy analyses, rather than dosimetry. At the same time, it is recognized that treatment planning based on proper dosimetry is of vital importance for the optimization of the results of RE. The heterogeneous and often clustered intrahepatic biodistribution of millions of point-source radioactive particles poses a challenge for dosimetry. Several studies found a relationship between absorbed doses and treatment outcome, with regard to both toxicity and efficacy. This should ultimately lead to improved patient selection and individualized treatment planning. New calculation methods and imaging techniques and a new generation of microspheres for image-guided RE will all contribute to these improvements. The aim of this review is to give insight into the latest and most important developments in RE dosimetry and to suggest future directions on patient selection, individualized treatment planning, and study designs.

  8. Internal dosimetry technical basis manual

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-20

    The internal dosimetry program at the Savannah River Site (SRS) consists of radiation protection programs and activities used to detect and evaluate intakes of radioactive material by radiation workers. Examples of such programs are: air monitoring; surface contamination monitoring; personal contamination surveys; radiobioassay; and dose assessment. The objectives of the internal dosimetry program are to demonstrate that the workplace is under control and that workers are not being exposed to radioactive material, and to detect and assess inadvertent intakes in the workplace. The Savannah River Site Internal Dosimetry Technical Basis Manual (TBM) is intended to provide a technical and philosophical discussion of the radiobioassay and dose assessment aspects of the internal dosimetry program. Detailed information on air, surface, and personal contamination surveillance programs is not given in this manual except for how these programs interface with routine and special bioassay programs.

  9. Medical dosimetry in Hungary

    Science.gov (United States)

    Turák, O.; Osvay, M.; Ballay, L.

    2012-09-01

    Radiation exposure of medical staff during cardiological and radiological procedures was investigated. The exposure of medical staff is directly connected to patient exposure. The aim of this study was to determine the distribution of doses on uncovered part of body of medical staff using LiF thermoluminescent (TL) dosimeters in seven locations. Individual Kodak film dosimeters (as authorized dosimetry system) were used for the assessment of medical staff's effective dose. Results achieved on dose distribution measurements confirm that wearing only one film badge under the lead apron does not provide enough information on the personal dose. The value of estimated annual doses on eye lens and extremities (fingers) were in good correlation with international publications.

  10. Dosimetry of iodoantipyrine

    International Nuclear Information System (INIS)

    Dosimetry of iodoantipyrine labeled with radioactive iodine was determined by measuring the biodistribution of 131I-iodoantipyrine in 41 female rabbits. Following administration of the radiopharmaceutical, subjects were killed at 0.5, 6, 12, 17, 24, 36, and 48 h. Organs and samples of tissues and body fluids were assayed. Results were corrected for physical decay. Exponential functions were employed to describe the time-concentration curves; representative value would be the biological half life of 9.96±0.55 h for blood. Cumulated activity estimates for 123I, 125I and 131I were then computed. Extrapolation to absorbed dose in humans followed the formulation of the Medical International Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine. The whole body absorbed doses are 0.7 μGray, 0.5 μGray and 2.9 μGray per MBq of 123I, 123I, and 131I administered respectively. (orig.)

  11. Strahlungsmessung und Dosimetrie

    CERN Document Server

    Krieger, Hanno

    2013-01-01

    „Strahlungsquellen und Dosimetrie“ ist Teil einer Lehrbuchreihe zur Strahlungsphysik und zum Strahlenschutz. Der erste Teil befasst sich mit den physikalischen Grundlagen der Strahlungsdetektoren und der Strahlungsmessung. Im zweiten Teil werden die Konzepte und Verfahren der klinischen Dosimetrie dargestellt. Der dritte Abschnitt erläutert ausführlich die Dosisverteilungen der klinisch angewendeten Strahlungsarten. Im vierten Teil werden weitere Messaufgaben der Strahlungsphysik einschließlich der Messsysteme für die Bildgebung mit Röntgenstrahlung dargestellt. Neben den grundlegenden Ausführungen enthält dieser Band im laufenden Text zahlreiche Tabellen und Grafiken zur technischen und medizinischen Radiologie, die bei der praktischen Arbeit sehr hilfreich sein können und 199 Übungsaufgaben mit Lösungen zur Vertiefung der Inhalte. Für die zweite Auflage wurden die Darstellungen der Elektronen- und der Protonendosimetrie sowie der bildgebenden Verfahren mit Computertomografen deutlich erweit...

  12. Hanford internal dosimetry program manual

    International Nuclear Information System (INIS)

    This document describes the Hanford Internal Dosimetry program. Program Services include administrating the bioassay monitoring program, evaluating and documenting assessments of internal exposure and dose, ensuring that analytical laboratories conform to requirements, selecting and applying appropriate models and procedures for evaluating internal radionuclide deposition and the resulting dose, and technically guiding and supporting Hanford contractors in matters regarding internal dosimetry. 13 refs., 16 figs., 42 tabs

  13. Fifth international radiopharmaceutical dosimetry symposium

    International Nuclear Information System (INIS)

    This meeting was held to exchange information on how to get better estimates of the radiation absorbed dose. There seems to be a high interest of late in patient dosimetry; discussions were held in the light of revised risk estimates for radiation. Topics included: Strategies of Dose Assessment; Dose Estimation for Radioimmunotherapy; Dose Calculation Techniques and Models; Dose Estimation for Positron Emission Tomography (PET); Kinetics for Dose Estimation; and Small Scale Dosimetry and Microdosimetry. (VC)

  14. Hanford internal dosimetry program manual

    Energy Technology Data Exchange (ETDEWEB)

    Carbaugh, E.H.; Sula, M.J.; Bihl, D.E.; Aldridge, T.L.

    1989-10-01

    This document describes the Hanford Internal Dosimetry program. Program Services include administrating the bioassay monitoring program, evaluating and documenting assessments of internal exposure and dose, ensuring that analytical laboratories conform to requirements, selecting and applying appropriate models and procedures for evaluating internal radionuclide deposition and the resulting dose, and technically guiding and supporting Hanford contractors in matters regarding internal dosimetry. 13 refs., 16 figs., 42 tabs.

  15. Dosimetry in radionuclide therapy

    International Nuclear Information System (INIS)

    While it is known that therapeutic effects of radionuclides are due to absorbed radiation dose and to radiosensitivity, individual dosimetry in 'Gy' is practiced rarely in clinical Nuclear Medicine but 'doses' are described in 'mCi' or 'MBq', which is only indirectly related to 'Gy' in the target. To estimate 'Gy', the volume of the target, maximum concentration of the radiopharmaceutical in it and residence time should be assessed individually. These parameters can be obtained usually only with difficulty, involving possibly also quantitative SPET or PET, modern imaging techniques (sonography, CT, MRT), substitution of y- or positron emitting radiotracers for β-emitting radiopharmaceuticals as well as whole-body distribution studies. Residence time can be estimated by obtaining data on biological half-life of a comparable tracer and transfer of these data in the physical characteristics of the therapeutic agent. With all these possibilities for gross dosimetry the establishment of a dose-response-relation should be possible. As distribution of the radiopharmaceutical in lesions is frequently inhomogenous and microdosimetric conditions are difficult to assess in vivo as yet, it could be observed since decades that empirically set, sometimes 'fixed' doses (mCi or MBq) can also be successful in many diseases. Detailed dosimetric studies, however, are work- and cost-intensive. Nevertheless, one should be aware at a time when more sophisticated therapeutic possibilities in Nuclear Medicine arise, that we should try to estimate radiation dose (Gy) in our new methods even as differences in individual radiosensitivity cannot be assessed yet and studies to define individual radiosensitivity in lesions should be encouraged. (author)

  16. Main: ANAERO5CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO5CONSENSUS S000481 05-November-2005 (last modified) kehi One of 16 motifs found in silico...ty et al., 2005); Arbitrary named ANAERO5CONSENSUS by the PLACEdb curator; See also S000477, S000478, S00047...); Hordeum vulgare (barley); Oryza sativa (rice); Petunia hybrida (petunia); Lycopersicon esculentum (tomato); TTCCCTGTT ...

  17. Main: ANAERO2CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO2CONSENSUS S000478 05-November-2005 (last modified) kehi One of 16 motifs found in silico...ty et al., 2005); Arbitrary named ANAERO2CONSENSUS by the PLACEdb curator; See also S000477, S000479, S00048...); Hordeum vulgare (barley); Oryza sativa (rice); Petunia hybrida (petunia); Lycopersicon esculentum (tomato); AGCAGC ...

  18. Main: ANAERO1CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO1CONSENSUS S000477 05-November-2005 (last modified) kehi One of 16 motifs found in silico...ty et al., 2005); Arbitrary named ANAERO1CONSENSUS by the PLACEdb curator; See also S000478, S000479, S00048...); Hordeum vulgare (barley); Oryza sativa (rice); Petunia hybrida (petunia); Lycopersicon esculentum (tomato); AAACAAA ...

  19. Main: ANAERO3CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO3CONSENSUS S000479 05-November-2005 (last modified) kehi One of 16 motifs found in silico...ty et al., 2005); Arbitrary named ANAERO3CONSENSUS by the PLACEdb curator; See also S000477, S000478, S00048...); Hordeum vulgare (barley); Oryza sativa (rice); Petunia hybrida (petunia); Lycopersicon esculentum (tomato); TCATCAC ...

  20. GENII (Generation II): The Hanford Environmental Radiation Dosimetry Software System: Volume 3, Code maintenance manual: Hanford Environmental Dosimetry Upgrade Project

    Energy Technology Data Exchange (ETDEWEB)

    Napier, B.A.; Peloquin, R.A.; Strenge, D.L.; Ramsdell, J.V.

    1988-09-01

    The Hanford Environmental Dosimetry Upgrade Project was undertaken to incorporate the internal dosimetry models recommended by the International Commission on Radiological Protection (ICRP) in updated versions of the environmental pathway analysis models used at Hanford. The resulting second generation of Hanford environmental dosimetry computer codes is compiled in the Hanford Environmental Dosimetry System (Generation II, or GENII). This coupled system of computer codes is intended for analysis of environmental contamination resulting from acute or chronic releases to, or initial contamination of, air, water, or soil, on through the calculation of radiation doses to individuals or populations. GENII is described in three volumes of documentation. This volume is a Code Maintenance Manual for the serious user, including code logic diagrams, global dictionary, worksheets to assist with hand calculations, and listings of the code and its associated data libraries. The first volume describes the theoretical considerations of the system. The second volume is a Users' Manual, providing code structure, users' instructions, required system configurations, and QA-related topics. 7 figs., 5 tabs.

  1. GENII [Generation II]: The Hanford Environmental Radiation Dosimetry Software System: Volume 3, Code maintenance manual: Hanford Environmental Dosimetry Upgrade Project

    International Nuclear Information System (INIS)

    The Hanford Environmental Dosimetry Upgrade Project was undertaken to incorporate the internal dosimetry models recommended by the International Commission on Radiological Protection (ICRP) in updated versions of the environmental pathway analysis models used at Hanford. The resulting second generation of Hanford environmental dosimetry computer codes is compiled in the Hanford Environmental Dosimetry System (Generation II, or GENII). This coupled system of computer codes is intended for analysis of environmental contamination resulting from acute or chronic releases to, or initial contamination of, air, water, or soil, on through the calculation of radiation doses to individuals or populations. GENII is described in three volumes of documentation. This volume is a Code Maintenance Manual for the serious user, including code logic diagrams, global dictionary, worksheets to assist with hand calculations, and listings of the code and its associated data libraries. The first volume describes the theoretical considerations of the system. The second volume is a Users' Manual, providing code structure, users' instructions, required system configurations, and QA-related topics. 7 figs., 5 tabs

  2. Between consensus and contestation.

    Science.gov (United States)

    Weale, Albert

    2016-08-15

    Purpose - Noting that discussions of public participation and priority setting typically presuppose certain political theories of democracy, the purpose of this paper is to discuss two theories: the consensual and the agonistic. The distinction is illuminating when considering the difference between institutionalized public participation and contestatory participation. Design/methodology/approach - The approach is a theoretical reconstruction of two ways of thinking about public participation in relation to priority setting in health care, drawing on the work of Habermas, a deliberative theorist, and Mouffe, a theorist of agonism. Findings - The different theoretical approaches can be associated with different ways of understanding priority setting. In particular, agonistic democratic theory would understand priority setting as system of inclusions and exclusions rather than the determination of a consensus of social values, which is the typical deliberative way of thinking about the issues. Originality/value - The paper shows the value of drawing out explicitly the tacit assumptions of practices of political participation in order to reveal their scope and limitations. It suggests that making such theoretical presuppositions explicit has value for health services management in recognizing these implicit choices. PMID:27468774

  3. Consensus on consensus: a synthesis of consensus estimates on human-caused global warming

    Science.gov (United States)

    Cook, John; Oreskes, Naomi; Doran, Peter T.; Anderegg, William R. L.; Verheggen, Bart; Maibach, Ed W.; Carlton, J. Stuart; Lewandowsky, Stephan; Skuce, Andrew G.; Green, Sarah A.; Nuccitelli, Dana; Jacobs, Peter; Richardson, Mark; Winkler, Bärbel; Painting, Rob; Rice, Ken

    2016-04-01

    The consensus that humans are causing recent global warming is shared by 90%-100% of publishing climate scientists according to six independent studies by co-authors of this paper. Those results are consistent with the 97% consensus reported by Cook et al (Environ. Res. Lett. 8 024024) based on 11 944 abstracts of research papers, of which 4014 took a position on the cause of recent global warming. A survey of authors of those papers (N = 2412 papers) also supported a 97% consensus. Tol (2016 Environ. Res. Lett. 11 048001) comes to a different conclusion using results from surveys of non-experts such as economic geologists and a self-selected group of those who reject the consensus. We demonstrate that this outcome is not unexpected because the level of consensus correlates with expertise in climate science. At one point, Tol also reduces the apparent consensus by assuming that abstracts that do not explicitly state the cause of global warming (‘no position’) represent non-endorsement, an approach that if applied elsewhere would reject consensus on well-established theories such as plate tectonics. We examine the available studies and conclude that the finding of 97% consensus in published climate research is robust and consistent with other surveys of climate scientists and peer-reviewed studies.

  4. Dosimetry requirements derived from the sterilization standards

    DEFF Research Database (Denmark)

    Miller, A.

    1998-01-01

    The main standards for radiation sterilization, ISO 11137 and EN 552, rest the documentation for the properly executed sterilization process on dosimetry. Both standards describe general requirements to the dosimetry system: The dose measurements must be traceable to national standards...

  5. Thermoluminescence Dosimetry Applied to Radiation Protection

    DEFF Research Database (Denmark)

    Christensen, Poul; Bøtter-Jensen, Lars; Majborn, Benny

    1982-01-01

    This is a general review of the present state of the development and application of thermoluminescence dosimetry (TLD) for radiation protection purposes. A description is given of commonly used thermoluminescent dosimeters and their main dosimetric properties, e.g. energy response, dose range......, fading, and LET dependence. The applications of thermoluminescence dosimetry in routine personnel monitoring, accident dosimetry, u.v. radiation dosimetry, and environmental monitoring are discussed with particular emphasis on current problems in routine personnel monitoring. Finally, the present state...

  6. Biological dosimetry; Dosimetria biologica

    Energy Technology Data Exchange (ETDEWEB)

    Guerrero C, C.; Arceo M, C., E-mail: citlali.guerrero@inin.gob.m [ININ, Departamento de Biologia, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2010-07-01

    In the Instituto Nacional de Investigaciones Nucleares (ININ) the works to establish a laboratory of biological dosimetry were initiated in 1998, with the purpose that could assist any situation with respect to the exposition to radiation, so much of the occupational exposed personnel as of individuals not related with the handling of radio-active material. The first activity that was realized was to develop the corresponding curves in vitro of dose response for different qualities and radiation types. In the year 2000 the curve corresponding to the gamma radiation of {sup 60}Co was published and up to 2002 the curve corresponding to the X rays of 58 KeV, 120 and 250 kVp. In all the cases, the curves contain the requirements to be used in the determination of the exposition dose. At the present time the curves dose-response are developing for neutrons take place in the reactor Triga Mark III of ININ. Additionally to these activities, cases of suspicion of accidental exposition to radiation have been assisted, using in a beginning the curves published by the IAEA and, from the year 2000, the curves developed in the ININ. (Author)

  7. Fast neutron dosimetry

    International Nuclear Information System (INIS)

    During 1988--1990 the magnetic resonance dosimetry project was completed, as were the 250 MeV proton shielding measurements. The first cellular experiment using human cells in vitro at the 1 GeV electron storage ring was also accomplished. More detail may be found in DOE Report number-sign DOE/EV/60417-002 and the open literature cited in the individual progress subsections. We report Kinetic Energy Released in Matter (KERMA), factor measurements in several elements of critical importance to neutron radiation therapy and radiation protection for space habitation and exploration for neutron energies below 30 MeV. The results of this effort provide the only direct measurements of the oxygen and magnesium kerma factors above 20 MeV neutron energy, and the only measurements of the iron kerma factor above 15 MeV. They provide data of immediate relevance to neutron radiotherapy and impose strict criteria for normalizing and testing nuclear models used to calculate kerma factors at higher neutron energies

  8. Nuclear accident dosimetry intercomparison studies.

    Science.gov (United States)

    Sims, C S

    1989-09-01

    Twenty-two nuclear accident dosimetry intercomparison studies utilizing the fast-pulse Health Physics Research Reactor at the Oak Ridge National Laboratory have been conducted since 1965. These studies have provided a total of 62 different organizations a forum for discussion of criticality accident dosimetry, an opportunity to test their neutron and gamma-ray dosimetry systems under a variety of simulated criticality accident conditions, and the experience of comparing results with reference dose values as well as with the measured results obtained by others making measurements under identical conditions. Sixty-nine nuclear accidents (27 with unmoderated neutron energy spectra and 42 with eight different shielded spectra) have been simulated in the studies. Neutron doses were in the 0.2-8.5 Gy range and gamma doses in the 0.1-2.0 Gy range. A total of 2,289 dose measurements (1,311 neutron, 978 gamma) were made during the intercomparisons. The primary methods of neutron dosimetry were activation foils, thermoluminescent dosimeters, and blood sodium activation. The main methods of gamma dose measurement were thermoluminescent dosimeters, radiophotoluminescent glass, and film. About 68% of the neutron measurements met the accuracy guidelines (+/- 25%) and about 52% of the gamma measurements met the accuracy criterion (+/- 20%) for accident dosimetry. PMID:2777549

  9. Is There a Consensus on Consensus Methodology? Descriptions and Recommendations for Future Consensus Research.

    Science.gov (United States)

    Waggoner, Jane; Carline, Jan D; Durning, Steven J

    2016-05-01

    The authors of this article reviewed the methodology of three common consensus methods: nominal group process, consensus development panels, and the Delphi technique. The authors set out to determine how a majority of researchers are conducting these studies, how they are analyzing results, and subsequently the manner in which they are reporting their findings. The authors conclude with a set of guidelines and suggestions designed to aid researchers who choose to use the consensus methodology in their work.Overall, researchers need to describe their inclusion criteria. In addition to this, on the basis of the current literature the authors found that a panel size of 5 to 11 members was most beneficial across all consensus methods described. Lastly, the authors agreed that the statistical analyses done in consensus method studies should be as rigorous as possible and that the predetermined definition of consensus must be included in the ultimate manuscript. More specific recommendations are given for each of the three consensus methods described in the article.

  10. Initial radiation dosimetry at Hiroshima and Nagasaki

    International Nuclear Information System (INIS)

    The dosimetry of A-bomb survivors at Hiroshima and Nagasaki is discussed in light of the new dosimetry developed in 1980 by the author. The important changes resulting from the new dosimetry are the ratios of neutron to gamma doses, particularly at Hiroshima. The implications of these changes in terms of epidemiology and radiation protection standards are discussed

  11. Information from the Dosimetry Service

    CERN Multimedia

    2006-01-01

    Please note the following opening hours of the Service: In June: Every morning from 8:30 to 12:00 In July: Mondays, Wednesdays and Fridays from 8:30 to 11:30 Closed all day on Tuesdays and Thursdays From 31st July onwards: Every morning from 8:30 to 12:00 The Service is closed in the afternoons. We should like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCTs) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats. Dosimetry Service Tel 72155 Bldg. 24 E 011 Dosimetry.service@cern.ch http://cern.ch/rp-dosimetry

  12. External audit in radiotherapy dosimetry

    International Nuclear Information System (INIS)

    Quality audit forms an essential part of any comprehensive quality assurance programme. This is true in radiotherapy generally and in specific areas such as radiotherapy dosimetry. Quality audit can independently test the effectiveness of the quality system and in so doing can identify problem areas and minimize their possible consequences. Some general points concerning quality audit applied to radiotherapy are followed by specific discussion of its practical role in radiotherapy dosimetry, following its evolution from dosimetric intercomparison exercises to routine measurement-based on-going audit in the various developing audit networks both in the UK and internationally. Specific examples of methods and results are given from some of these, including the Scottish+ audit group. Quality audit in radiotherapy dosimetry is now well proven and participation by individual centres is strongly recommended. Similar audit approaches are to be encouraged in other areas of the radiotherapy process. (author)

  13. For information: Individual dosimetry service

    CERN Document Server

    2004-01-01

    The service has noticed that there are dosimeter holders who have changed their activities and thus have no longer need of dosimeter as a permanent basis in their work (persons who go rarely to the controlled areas). The reduction of persons in the regular distribution list of dosimeters will lighten the work of the service (distribution, evaluation and consolidation of doses) as well as the work of the distributors, needless to say the economical input this would have for CERN. For the persons who only need a dosimeter temporarily we would like to remind that there is a quick and simple procedure to have one immediately from the Individual Dosimetry Service. Please contact the service (dosimetry.service@cern.ch) if you do not need a dosimeter regularly. Thank you for your cooperation. http://cern.ch/rp-dosimetry

  14. Dosimetry standards for radiation processing

    International Nuclear Information System (INIS)

    For irradiation treatments to be reproducible in the laboratory and then in the commercial environment, and for products to have certified absorbed doses, standardized dosimetry techniques are needed. This need is being satisfied by standards being developed by experts from around the world under the auspices of Subcommittee E10.01 of the American Society for Testing and Materials (ASTM). In the time period since it was formed in 1984, the subcommittee has grown to 150 members from 43 countries, representing a broad cross-section of industry, government and university interests. With cooperation from other international organizations, it has taken the combined part-time effort of all these people more than 13 years to complete 24 dosimetry standards. Four are specifically for food irradiation or agricultural applications, but the majority apply to all forms of gamma, x-ray, Bremsstrahlung and electron beam radiation processing, including dosimetry for sterilization of health care products and the radiation processing of fruits, vegetables, meats, spices, processed foods, plastics, inks, medical wastes and paper. An additional 6 standards are under development. Most of the standards provide exact procedures for using individual dosimetry systems or for characterizing various types of irradiation facilities, but one covers the selection and calibration of dosimetry systems, and another covers the treatment of uncertainties. Together, this set of standards covers essentially all aspects of dosimetry for radiation processing. The first 20 of these standards have been adopted in their present form by the International Organization of Standardization (ISO), and will be published by ISO in 1999. (author)

  15. Radiation dosimetry and radiation biophysics

    International Nuclear Information System (INIS)

    Radiation dosimetry and radiation biophysics are two closely integrated programs whose joint purpose is to explore the connections between the primary physical events produced by radiation and their biological consequences in cellular systems. The radiation dosimetry program includes the theoretical description of primary events and their connection with the observable biological effects. This program also is concerned with the design and measurement of physical parameters used in theory or to support biological experiments. The radiation biophysics program tests and uses the theoretical developments for experimental design, and provides information for further theoretical development through experiments on cellular systems

  16. Radiation dosimetry and radiation biophysics

    International Nuclear Information System (INIS)

    Radiation dosimetry and radiation biophysics are two closely integrated programs whose joint purpose is to explore the connections between the primary physical events produced by radiation and their biological consequences in cellular systems. The radiation dosimetry program includes the theoretical description of primary events and their connection with the observable biological effects. This program also is concerned with design and measurement of those physical parameters used in the theory or to support biological experiments. The radiation biophysics program tests and makes use of the theoretical developments for experimental design. Also, this program provides information for further theoretical development through experiments on cellular systems

  17. Information from the Dosimetry Service

    CERN Multimedia

    2006-01-01

    CERN Staff and Users can now consult their dose records for an individual or an organizational unit with HRT. Please see more information on our web page http://cern.ch/rp-dosimetry. The Dosimetry Service is open every morning from 8.30 - 12.00, and closed in the afternoons. We would like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCT's) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats.

  18. Information from the Dosimetry Service

    CERN Multimedia

    2006-01-01

    CERN Staff and Users can now consult their dose records for an individual or an organizational unit with HRT. Please see more information on our web page: http://cern.ch/rp-dosimetry. The Dosimetry Service is open every morning from 8.30 to 12.00 and is closed in the afternoons. We would like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCT's) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats.

  19. Ocular allergy latin american consensus

    Directory of Open Access Journals (Sweden)

    Myrna Serapião dos Santos

    2011-12-01

    Full Text Available PURPOSE: To establish current definition, classification and staging, and to develop diagnosis and treatment recommendations for ocular allergy, by using Delphi approach. METHODS: Ten Latin American experts on ocular allergy participated in a 4-round Delphi panel approach. Four surveys were constructed and answered by panelists. A two-thirds majority was defined as consensus. Definition, classification, staging and diagnosis and treatment recommendations were the main outcomes. RESULTS: "Ocular allergy" was proposed as the general term to describe ocular allergic diseases. Consensus regarding classification was not reached. Signs and symptoms were considered extremely important for the diagnosis. It was consensus that a staging system should be proposed based on the disease severity. Environmental control, avoidance of allergens and the use of artificial tears were recommended as first line treatment. The secondary treatment should include topical anti-histamines, mast cell stabilizers and multi actions drugs. Topical non-steroidal anti-inflammatory and vasoconstrictors were not recommended. Topical corticosteroids were recommended as third line of treatment for the most severe keratoconjunctivitis. Consensus was not reached regarding the use of systemic corticosteroids or immunosuppressant. Surgical approach and unconventional treatments were not recommended as routine. CONCLUSION: The task of creating guidelines for ocular allergies showed to be very complex. Many controversial topics remain unsolved. A larger consensus including experts from different groups around the world may be needed to further improve the current recommendations for several aspects of ocular allergy.

  20. In aqua vivo EPID dosimetry

    NARCIS (Netherlands)

    Wendling, M.; McDermott, L.N.; Mans, A.; Olaciregui-Ruiz, I.; Pecharroman-Gallego, R.; Sonke, J.J.; Stroom, J.; Herk, M. van; Mijnheer, B.J.

    2012-01-01

    PURPOSE: At the Netherlands Cancer Institute--Antoni van Leeuwenhoek Hospital in vivo dosimetry using an electronic portal imaging device (EPID) has been implemented for almost all high-energy photon treatments of cancer with curative intent. Lung cancer treatments were initially excluded, because t

  1. Portal dosimetry in wedged beams

    NARCIS (Netherlands)

    Spreeuw, H.; Rozendaal, R.; Camargo, P.; Mans, A.; Wendling, M.; Olaciregui-Ruiz, I.; Sonke, J.J.; Herk, M. van; Mijnheer, B.

    2015-01-01

    Portal dosimetry using electronic portal imaging devices (EPIDs) is often applied to verify high-energy photon beam treatments. Due to the change in photon energy spectrum, the resulting dose values are, however, not very accurate in the case of wedged beams if the pixel-to-dose conversion for the s

  2. Plutonium worker dosimetry.

    Science.gov (United States)

    Birchall, Alan; Puncher, M; Harrison, J; Riddell, A; Bailey, M R; Khokryakov, V; Romanov, S

    2010-05-01

    Epidemiological studies of the relationship between risk and internal exposure to plutonium are clearly reliant on the dose estimates used. The International Commission on Radiological Protection (ICRP) is currently reviewing the latest scientific information available on biokinetic models and dosimetry, and it is likely that a number of changes to the existing models will be recommended. The effect of certain changes, particularly to the ICRP model of the respiratory tract, has been investigated for inhaled forms of (239)Pu and uncertainties have also been assessed. Notable effects of possible changes to respiratory tract model assumptions are (1) a reduction in the absorbed dose to target cells in the airways, if changes under consideration are made to the slow clearing fraction and (2) a doubling of absorbed dose to the alveolar region for insoluble forms, if evidence of longer retention times is taken into account. An important factor influencing doses for moderately soluble forms of (239)Pu is the extent of binding of dissolved plutonium to lung tissues and assumptions regarding the extent of binding in the airways. Uncertainty analyses have been performed with prior distributions chosen for application in epidemiological studies. The resulting distributions for dose per unit intake were lognormal with geometric standard deviations of 2.3 and 2.6 for nitrates and oxides, respectively. The wide ranges were due largely to consideration of results for a range of experimental data for the solubility of different forms of nitrate and oxides. The medians of these distributions were a factor of three times higher than calculated using current default ICRP parameter values. For nitrates, this was due to the assumption of a bound fraction, and for oxides due mainly to the assumption of slower alveolar clearance. This study highlights areas where more research is needed to reduce biokinetic uncertainties, including more accurate determination of particle transport rates

  3. The personal dosimetry in Mexico

    International Nuclear Information System (INIS)

    The Personal Dosimetry in Mexico, has an approximately 30 year-old history; and it had been and it is at the moment, one of the more important resources with which the personnel that works with ionizing radiation sources counts for its protection. The Personal Dosimetry begins with the film dosimetry, technique that even continues being used at the present time by some users, and the main reason of its use is for economic reasons. At the moment this technique, it has been surpassed, by the Thermoluminescent dosimetry, which has taken a lot of peak, mainly by the technological development with which it is counted at the present time; what has given as a result that this technique becomes tip technology; that supported in the characteristic of the used materials, as the handling and processing of the information associated with the new PC, digitizer cards, software etc, what has allowed increases it potential. In this work the current necessities of the market are presented as well as an analysis of the future real necessities in Mexico, at national level, the companies that provide this service and that they spread to satisfy this necessity of the market, including the different used technologies are also mentioned. The application ranges, at the same time, of the advantages and disadvantages of the different systems of Personal Dosimetry in the market. The companies that at the moment provide the service of Personal Dosimetry, its use materials and equipment in indistinct form, for the monitoring of gamma radiation, beta particles, different qualities of x-ray radiation, and sometimes neutrons. The monitoring of the exposed personnel at the diverse sources of ionizing radiation mentioned is carried out in many occasions without having with the materials (detectors), neither the appropriate infrastructure and therefore without the quality control that guarantees a correct evaluation of the dose equivalent, as a result of the exposure to the ionizing radiations; it

  4. Consensus clustering in complex networks

    CERN Document Server

    Lancichinetti, Andrea; 10.1038/srep00336

    2012-01-01

    The community structure of complex networks reveals both their organization and hidden relationships among their constituents. Most community detection methods currently available are not deterministic, and their results typically depend on the specific random seeds, initial conditions and tie-break rules adopted for their execution. Consensus clustering is used in data analysis to generate stable results out of a set of partitions delivered by stochastic methods. Here we show that consensus clustering can be combined with any existing method in a self-consistent way, enhancing considerably both the stability and the accuracy of the resulting partitions. This framework is also particularly suitable to monitor the evolution of community structure in temporal networks. An application of consensus clustering to a large citation network of physics papers demonstrates its capability to keep track of the birth, death and diversification of topics.

  5. ESR dosimetry: achievements and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Baffa, O., E-mail: baffa@usp.br [Universidade de Sao Paulo, Departamento de Fisica, Av. Bandeirantes 3900, 14040-901 Ribeirao Preto, Sao Paulo (Brazil)

    2015-10-15

    Full text: Electron Spin Resonance (ESR), also known as Electron Paramagnetic Resonance (EPR) and more recently as Electron Magnetic Resonance (Emr), is a spectroscopy technique able to detect unpaired electrons such as those created by the interaction ionizing radiation with matter. When the unpaired electrons created by ionizing radiation are stable over some reasonable time, ESR can be used to measure the radiation dose deposited in the material under study. In principle, any insulating material that satisfies this requisite can be used as a dosimeter. ESR has been used in retrospective dosimetry in case of radiological accidents using natural constituents of human body such as teeth, bones and nails as well as fortuitous materials as sugar, sweeteners and plastics. When using teeth the typical detected dose is 0.5 Gy for, for X-Band spectrometers (9 GHz) and even lower doses if higher frequency spectrometers are used. Clinical dosimetry is another area of potential use of this dosimetric modality. In this application the amino acid alanine has been proposed and being used. Alanine dosimeters are very easy to prepare and require no complicated treatments for use. Alanine/ESR dosimetry satisfies many of the required properties for clinical applications such as water equivalent composition, independence of response for the energy range used in therapy and high precision. Other organic materials such as ammonium tartrate are being investigated to increase the sensitivity of ESR for clinical applications. Finally, industrial applications can also benefit from this dosimetry. The challenges to expand applications, the number of users and research groups of ESR dosimetry will be discussed. (Author)

  6. C3 glomerulopathy: consensus report

    Science.gov (United States)

    Pickering, Matthew C; D'Agati, Vivette D; Nester, Carla M; Smith, Richard J; Haas, Mark; Appel, Gerald B; Alpers, Charles E; Bajema, Ingeborg M; Bedrosian, Camille; Braun, Michael; Doyle, Mittie; Fakhouri, Fadi; Fervenza, Fernando C; Fogo, Agnes B; Frémeaux-Bacchi, Véronique; Gale, Daniel P; Goicoechea de Jorge, Elena; Griffin, Gene; Harris, Claire L; Holers, V Michael; Johnson, Sally; Lavin, Peter J; Medjeral-Thomas, Nicholas; Paul Morgan, B; Nast, Cynthia C; Noel, Laure-Hélène; Peters, D Keith; Rodríguez de Córdoba, Santiago; Servais, Aude; Sethi, Sanjeev; Song, Wen-Chao; Tamburini, Paul; Thurman, Joshua M; Zavros, Michael; Cook, H Terence

    2013-01-01

    C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the definition of C3 glomerulopathy, appropriate complement investigations that should be performed in these patients, and how complement therapeutics should be explored in the condition. This meeting report represents the current consensus view of the group. PMID:24172683

  7. Proceedings of the 5. symposium on neutron dosimetry. Beam dosimetry

    International Nuclear Information System (INIS)

    Proceedings of the fifth symposium on neutron dosimetry, organized at Neuherberg, 17-21 September 1984, by the Commission of the European Communities and the GSF Neuherberg, with the co-sponsorship of the US Department of Energy, Office of Health and Environmental Research. The proceedings deal with research on concepts, instruments and methods in radiological protection for neutrons and mixed neutron-gamma fields, including the generation, collection and evaluation of new dosimetric data, the derivation of relevant radiation protection quantitites, and the harmonization of experimental methods and instrumentation by intercomparison programmes. Besides radiation protection monitoring, the proceedings also report on the improvement of neutron beam dosimetry in the fields of radiobiology and radiation therapy

  8. The Copenhagen Consensus Conference 2016

    DEFF Research Database (Denmark)

    Bangsbo, Jens; Krustrup, Peter; Duda, Joan;

    2016-01-01

    From 4 to 7 April 2016, 24 researchers from 8 countries and from a variety of academic disciplines gathered in Snekkersten, Denmark, to reach evidence-based consensus about physical activity in children and youth, that is, individuals between 6 and 18 years. Physical activity is an overarching term...

  9. Reference: ANAERO2CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO2CONSENSUS Mohanty B, Krishnan SP, Swarup S, Bajic VB. Detection and prelimin...ary analysis of motifs in promoters of anaerobically induced genes of different plant species. Ann Bot (Lond).96: 669-681 (2005) in silico PubMed: 16027132 ...

  10. Reference: ANAERO3CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO3CONSENSUS Mohanty B, Krishnan SP, Swarup S, Bajic VB. Detection and prelimin...ary analysis of motifs in promoters of anaerobically induced genes of different plant species. Ann Bot (Lond).96: 669-681 (2005) in silico PubMed: 16027132 ...

  11. Reference: ANAERO4CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO4CONSENSUS Mohanty B, Krishnan SP, Swarup S, Bajic VB. Detection and prelimin...ary analysis of motifs in promoters of anaerobically induced genes of different plant species. Ann Bot (Lond).96: 669-681 (2005) in silico PubMed: 16027132 ...

  12. Reference: ANAERO5CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO5CONSENSUS Mohanty B, Krishnan SP, Swarup S, Bajic VB. Detection and prelimin...ary analysis of motifs in promoters of anaerobically induced genes of different plant species. Ann Bot (Lond).96: 669-681 (2005) in silico PubMed: 16027132 ...

  13. Reference: ANAERO1CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available ANAERO1CONSENSUS Mohanty B, Krishnan SP, Swarup S, Bajic VB. Detection and prelimin...ary analysis of motifs in promoters of anaerobically induced genes of different plant species. Ann Bot (Lond).96: 669-681 (2005) in silico PubMed: 16027132 ...

  14. Reference: GT1CONSENSUS [PLACE

    Lifescience Database Archive (English)

    Full Text Available GT1CONSENSUS Le Gourrierec J, Li YF, Zhou DX Transcriptional activation by Arabidop...sis GT-1 may be through interaction with TFIIA-TBP-TATA complex Plant J 18:663-668 (1999) PubMed: 10417717 ...

  15. Quantized average consensus with delay

    NARCIS (Netherlands)

    Jafarian, Matin; De Persis, Claudio

    2012-01-01

    Average consensus problem is a special case of cooperative control in which the agents of the network asymptotically converge to the average state (i.e., position) of the network by transferring information via a communication topology. One of the issues of the large scale networks is the cost of co

  16. Dosimetry by ESR spectroscopy of alanine

    International Nuclear Information System (INIS)

    Dosimetry based on electron spin resonance analysis of radiation-induced free radicals in amino acids (e.g. L-alanine) is relevant to biological dosimetry applications. Typical features are a wide dose range covering more than 5 decades (1-105Gy), energy independent response for photons above 100 keV, long-term stability of the ESR signal, and fast straightforward readout technique. Typical dosimeter samples, consisting of small pellets of microcrystalline amino acids in paraffin, are rugged, non-toxic, and insensitive to surface contaminations. Moreover, they are prepared homogeneously and inexpensively in large batches and can be evaluated repeatedly and supply archival dosimetry data. They have proven to be highly useful in various applications of radiation processing and sterilization dosimetry, food irradiation, quality control, radiation dosimetry, radiation therapy measurements, and as a reference system for dosimetry mailing intercomparisons. (author)

  17. NOTE FROM THE DOSIMETRY SERVICE

    CERN Multimedia

    2002-01-01

    During March, the Dosimetry Service will be opened from 8h30 to 12h in the morning and closed every afternoon.   We have established that many people, who are provided regularly with a personal dosimeter (film badge), have changed their activity and do not need it anymore, because they do not, or only exceptionally, enter controlled areas. If you are one of these persons, please contact the Personal Dosimeter Service (tel: 72155). There is a simplified procedure for obtaining a dosimeter if you have an immediate need for short-term visits in controlled areas. A reduction of the number of persons on the regular distribution list of dosimeters would decrease our and the distributors workload. It would also contribute to significant savings in the dosimetry, and thus CERN, budget. We thank you in advance for your understanding and for your collaboration.

  18. Dosimetry in radiotherapy. V.2

    International Nuclear Information System (INIS)

    A series of symposia on dosimetry in medicine and biology have been held by the IAEA in co-operation with WHO. The present symposium was the first one focusing on ''Dosimetry in Radiotherapy''. The papers presented reflected the different steps in the calibration chain such as the calibration standards established by the National Standards Laboratories and the conversion of the reading of calibrated instruments to the desired quantity, i.e. absorbed dose to water at a reference point in the user's beam at the radiotherapy clinic. The programme further examined the procedures necessary for optimization of the treatment of the patient, such as treatment planning methods, dose distribution studies, new techniques of dose measurement, improvements in the physical dose distributions/conformation therapy and special problems involved in total body treatments. Results of quality assurance in radiotherapy were presented from local hospitals as well as from national and international studies. Refs, figs and tabs

  19. Dosimetry in radiotherapy. V.1

    International Nuclear Information System (INIS)

    A series of symposia on dosimetry in medicine and biology have been held by the IAEA in co-operation with WHO. The present symposium was the first one focusing on ''Dosimetry in Radiotherapy''. The papers presented reflected the different steps in the calibration chain such as the calibration standards established by the National Standards Laboratories and the conversion of the reading of calibrated instruments to the desired quantity, i.e. absorbed dose to water at a reference point in the user's beam at the radiotherapy clinic. The programme further examined the procedures necessary for optimization of the treatment of the patient, such as treatment planning methods, dose distribution studies, new techniques of dose measurement, improvements in the physical dose distributions/conformation therapy and special problems involved in total body treatments. Results of quality assurance in radiotherapy were presented from local hospitals as well as from national and international studies. Refs, figs and tabs

  20. MISTI Shielding and Dosimetry Experiment Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Reliable on-orbit dosimetry is necessary for understanding effects of space radiation environments on spacecraft microelectronics performance and comparison of...

  1. Topical Review: Polymer gel dosimetry

    OpenAIRE

    Baldock, C; De Deene, Y; Doran, S.; Ibbott, G; Jirasek, A.; Lepage, M.; McAuley, K B; Oldham, M; Schreiner, L J

    2010-01-01

    Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose ...

  2. Fourth international radiopharmaceutical dosimetry symposium

    International Nuclear Information System (INIS)

    The focus of the Fourth International Radiopharmaceutical Dosimetry Symposium was to explore the impact of current developments in nuclear medicine on absorbed dose calculations. This book contains the proceedings of the meeting including the edited discussion that followed the presentations. Topics that were addressed included the dosimetry associated with radiolabeled monoclonal antibodies and blood elements, ultrashort-lived radionuclides, and positron emitters. Some specific areas of discussion were variations in absorbed dose as a result of alterations in the kinetics, the influence of radioactive contaminants on dose, dose in children and in the fetus, available instrumentation and techniques for collecting the kinetic data needed for dose calculation, dosimetry requirements for the review and approval of new radiopharmaceuticals, and a comparison of the effect on the thyroid of internal versus external irradiation. New models for the urinary blader, skeleton including the active marrow, and the blood were presented. Several papers dealt with the validity of traditional ''average-organ'' dose estimates to express the dose from particulate radiation that has a short range in tissue. These problems are particularly important in the use of monoclonal antibodies and agents used to measure intracellular functions. These proceedings have been published to provide a resource volume for anyone interested in the calculation of absorbed radiation dose

  3. EPR Dosimetry - Present and Future

    Energy Technology Data Exchange (ETDEWEB)

    Regulla, D.F. [GSF - National Research Centre for Environment and Health, Institute of Radiation Protection, 85764 Neuherberg (Germany)

    1999-07-01

    In the past, IAEA has played a central role in stipulating research and development in EPR high-dose standardisation as well as in coordinating and organising international dose intercomparison programs, within the Member States of the United Nations from the mid-seventies till today. The future tasks of EPR dosimetry seem to tend towards different subjects such as bio markers, biological radiation effects, post-accident dose reconstruction in the environment, and retrospective human dosimetry. The latter may be considered a promising tool for epidemiology on the way to re-define radiation risk of man for chronicle radiation exposures, based on e.g. South Ural civil population and radiation workers. There are on-going international activities in the field of standardising high-level dosimetry by the American Standards on Testing and Materials (Astm), and by the International Organisation of Standards (ISO). The International Commission on Radiation Units and Measurements (ICRU) is considering the establishment of relevant recommendations concerning industrial radiation processing, but also human dose reconstruction. (Author)

  4. Energy strategy: Roadmap to consensus

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-01

    The United States lacks a comprehensive approach to policy-making in the energy realm. Today, as in the past, individual constituency groups tend to focus on their particular aspect of the energy challenge. Many employ a decide-announce-defend'' approach to policy-making, setting out to secure a unilateral advantage for themselves. By so doing, they inevitably pit interest against interest. The result is a polarization of constituencies, and shortsighted policies designed to address the issue of the moment. The American Energy Assurance Council (AEAC) is a non-profit organization founded in 1987 for the sole purpose of facilitating progress toward a fair efficient wise, stable, and consensus-based national energy strategy. AEAC does not have a substantive policy agencies. Rather, we are committed to supporting a process whereby the many stakeholders and policy makers concerned with energy-related issues can come together in productive discourse, thereby overcoming ignorance of each other's positions. The Council seeks to act as a facilitative body, providing a safe'' context for inventive and creative thinking. We attempt to build a store of common knowledge, and to build on that store according to mutually agreed-upon groundrules, and employing sophisticated approaches to facilitation and mediation. This report, the National Energy Consensus Experiment (NECE), was an ambitious experiment in consensus-building. We learned a great deal from it, both in terms of substance and process, and we are convinced that it holds important lessons for others who may seek to build consensus in the public policy realm.

  5. Energy strategy: Roadmap to consensus

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-01

    The United States lacks a comprehensive approach to policy-making in the energy realm. Today, as in the past, individual constituency groups tend to focus on their particular aspect of the energy challenge. Many employ a ``decide-announce-defend`` approach to policy-making, setting out to secure a unilateral advantage for themselves. By so doing, they inevitably pit interest against interest. The result is a polarization of constituencies, and shortsighted policies designed to address the issue of the moment. The American Energy Assurance Council (AEAC) is a non-profit organization founded in 1987 for the sole purpose of facilitating progress toward a fair efficient wise, stable, and consensus-based national energy strategy. AEAC does not have a substantive policy agencies. Rather, we are committed to supporting a process whereby the many stakeholders and policy makers concerned with energy-related issues can come together in productive discourse, thereby overcoming ignorance of each other`s positions. The Council seeks to act as a facilitative body, providing a ``safe`` context for inventive and creative thinking. We attempt to build a store of common knowledge, and to build on that store according to mutually agreed-upon groundrules, and employing sophisticated approaches to facilitation and mediation. This report, the National Energy Consensus Experiment (NECE), was an ambitious experiment in consensus-building. We learned a great deal from it, both in terms of substance and process, and we are convinced that it holds important lessons for others who may seek to build consensus in the public policy realm.

  6. Canadian asthma consensus report, 1999

    OpenAIRE

    Boulet, L. P.; A. Becker; Bérubé, D; Beveridge, R.; Ernst, P

    1999-01-01

    OBJECTIVES: To provide physicians with current guidelines for the diagnosis and optimal management of asthma in children and adults, including pregnant women and the elderly, in office, emergency department, hospital and clinic settings. OPTIONS: The consensus group considered the roles of education, avoidance of provocative environmental and other factors, diverse pharmacotherapies, delivery devices and emergency and in-hospital management of asthma. OUTCOMES: Provision of the best control o...

  7. C3 glomerulopathy: consensus report.

    OpenAIRE

    Lavin, Peter

    2013-01-01

    PUBLISHED C3 glomerulopathy is a recently introduced pathological entity whose original definition was glomerular pathology characterized by C3 accumulation with absent or scanty immunoglobulin deposition. In August 2012, an invited group of experts (comprising the authors of this document) in renal pathology, nephrology, complement biology, and complement therapeutics met to discuss C3 glomerulopathy in the first C3 Glomerulopathy Meeting. The objectives were to reach a consensus on: the ...

  8. International consensus on safety principles

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency (IAEA) has been regularly requested by its Member States to provide evidence that radioactive waste can be managed safely and to help demonstrate a harmonization of approach at the international level by providing safety documents. In response, IAEA established a special series of safety documents devoted to radioactive waste management. These documents will be elaborated within the Radioactive Waste Safety Standards (RADWASS) programme [1,2] which covers all aspects of radioactive waste management. The RADWASS programme develops a series of international consensus documents on all parts of the safe management of radioactive waste, including disposal. The purpose of the RADWASS programme is to (i) document existing international consensus in the approaches and methodologies for safe radioactive waste management, (ii) create a mechanism to establish consensus where it does not exist and (iii) provide Member States with a comprehensive series of internationally agreed upon documents to complement national standards and criteria. This paper describes the RADWASS programme, and covers the structure, implementation plans and status of documents under preparation

  9. Patient dosimetry and protection in diagnostic radiology

    International Nuclear Information System (INIS)

    The paper discussed the following subjects: x-ray in medicine as they represent by far the largest man-made sources of population exposure to ionizing radiation, methods of patient dosimetry, entrance surface dose per radiograph, dose-area product per examination, dosimetry for assessing risk, potential of dose reduction

  10. High dose dosimetry for radiation processing

    International Nuclear Information System (INIS)

    Radiation processing today offers various advantages in the field of sterilization of medical and pharmaceutical products, food preservation, treatment of chemical materials and a variety of other products widely used in modern society, all of which are of direct relevance to health and welfare. The safety and economic importance of radiation processing is clearly recognized. It is understood that reliable dosimetry is a key parameter for quality assurance of radiation processing and irradiated products. Furthermore, the standardization of dosimetry can provide a justification for the regulatory approval of irradiated products and form the basis of international clearance for free trade. After the initiation of the Agency's high dose standardization programme (1977), the first IAEA Symposium on High Dose Dosimetry was organized in 1984. As a result, concern as to the necessity of reliable dosimetry has greatly escalated not only in the scientific community but also in the radiation processing industry. The second International Symposium on High Dose Dosimetry for Radiation Processing was held in Vienna from 5 to 9 November, 1990, with a view to providing an international forum for the exchange of technical information on up to date developments in this particular field. The scientific programme held promises for an authoritative account of the status of high dose dosimetry throughout the world in 1990. Forty-one papers presented at the meeting discussed the development of new techniques, the improvement of reference and routine dosimetry systems, and the quality control and assurance of dosimetry. Refs, figs and tabs

  11. Greatly improving consensus performance via predictive mechanism

    CERN Document Server

    Zhang, Hai-Tao; Chen, Michael ZhiQiang; Zhou, Tao

    2007-01-01

    An important natural phenomenon surfaces that ultrafast consensus can be achieved by introducing the predictive mechanism. By predicting the dynamics of the network several steps ahead and using this information in the design of the consensus protocol of each agent, it is shown that drastic improvement can be achieved in terms of the speed of convergence towards consensus without changing the topology of the network. Moreover, with the predictive mechanism, the range of sampling rates leading to consensus convergence is broadly expanded compared to the routine consensus protocol. In natural science, this study provides support for the idea that some predictive mechanisms exist in widely-spread biological swarms, flocks, and schools. From the industrial engineering point of view, inclusion of an efficient predictive mechanism allows for not only a significant increase in the speed of convergence toward consensus but also a reduction of the communication energy required to achieve a predefined consensus perform...

  12. ESR dosimetry using eggshells and tooth enamel for accidental dosimetry

    International Nuclear Information System (INIS)

    The CO2- signal of eggshells showed a good dose linearity and was appropriate in the wide dose range from 1 to 10 kGy, while ESR signal of CO2- in sea and fresh water shells were saturated at a dose od below 10 kGy. The minimum detectable dose and G-value of CO2- in eggshells were estimated 0.3 Gy and 0.28, respectively. The lifetime of CO2- in eggshells could not be determined exactly because of overlapping organic signals, however it is still sufficiently long for practical use as ESR dosimeter materials. Various bird's or reptile's eggshells would be available as natural retrospective ESR dosimeter materials after nuclear accidents. Eggshells will be useful for the food irradiation dosimetry in the dose range of about a few kGy. Tooth enamel is one of the most useful dosimeter materials in public at a accident because of its high sensitivity. ESR dosimetry will replace TLD in near future if the cost of an ESR reader is further reduced . (author)

  13. Radiation dosimetry and standards at the austrian dosimetry laboratory

    International Nuclear Information System (INIS)

    The Austrian Dosimetry Laboratory, established and operated in cooperation between the Austrian Research Center Seibersdorf and the Federal Office of Metrology and Surveying (Bundesamt and Eich- und Vermessungswesen) maintains the national primary standards for radiation dosimetry. Furthermore its tasks include routine calibration of dosemeters and dosimetric research. The irradiation facilities of the laboratory comprise three X-ray machines covering the voltage range from 5 kV to 420 kV constant potential, a 60Co teletherapy unit, a circular exposure system for routine batch calibration of personnel dosemeters with four gamma ray sources (60Co and 137Cs) and a reference source system with six gamma ray sources (60Co and 137Cs). In addition a set of calibrated beta ray sources are provided (147Pm, 204Tl and 90Sr). The dosimetric equipment consists of three free-air parallelplate ionization chambers serving as primary standards of exposure for the X-ray energy region, graphite cavity chambers with measured volume as primary standards for the gamma radiation of 137Cs and 60Co as well as different secondary standard ionization chambers covering the dose rate range from the natural background level up to the level of modern therapy accelerators. In addition for high energy photon and electron radiation a graphite calorimeter is provided as primary standard of absorbed dose. The principle experimental set-ups for the practical use of the standards are presented and the procedures for the calibration of the different types of dosemeters are described. (Author)

  14. Air Force neutron dosimetry program

    International Nuclear Information System (INIS)

    Approximately 1000 Air Force personnel are monitored for neutron radiation resulting from various sources at more than thirty worldwide locations. Neutron radiation spanning several orders of magnitude in energy is encountered. The Air Force currently uses albedo thermoluminescent neutron dosimeters for personnel monitoring. The energy dependence of the albedo neutron dosimeter is a current problem and the development of site specific correction factors is ongoing. A summary of data on the energy dependence is presented as well as efforts to develop algorithms for the dosimeter. An overview of current Air Force neutron dosimetry users and needs is also presented

  15. Radiation dosimetry by potassium feldspar

    Indian Academy of Sciences (India)

    Arun Pandya; S G Vaijapurkar; P K Bhatnagar

    2000-04-01

    The thermoluminescence (TL) properties of raw and annealed feldspar have been studied for their use in gamma dosimetry. The raw gamma exposed feldspar shows glow peaks at 120°C and 319°C. Gamma dose beyond 500 cGy can be measured without any significant fading even after 40 days of termination of exposure. The annealed feldspar shows a glow peak at 120°C after gamma exposure. This peak can be used to measure gamma doses beyond 25 cGy when the TL is measured after 24 h from termination of exposure.

  16. Phototherapy with low intensity laser in carrageenan-induced acute inflammatory process in mice paw - dosimetry studies; Fototerapia com laser em baixa intensidade em processo inflamatorio agudo induzido por carragenina em pata de camundongos - estudos de dosimetria

    Energy Technology Data Exchange (ETDEWEB)

    Meneguzzo, Daiane Thais

    2010-07-01

    The importance of modulation of inflammation on the treatment of inflammatory diseases and the difficulty in determining the laser irradiation parameters has led us to study the effects of different protocols of phototherapy with low intensity laser (power, energy, time and place of irradiation) in the treatment and prevention of edema in acute inflammatory process using the experimental model of paw edema induced by carrageenan (CGN) in three strains of mice (Balb-c, Swiss and C57BL/6). The first stage of the study evaluated different combinations of energy (1J and 3J) with different powers (30, 60 and 100mW) in Balb-C mice paw irradiated 1 and 2h after injection of CGN. The second stage studied different combinations of location (foot, inguinal lymph nodes and both) and exposure time (2 and 1h before, 1h and immediately before the CGN, 1 and 2h and 3.5 and 4.5h after CGN) using fixed irradiation parameters (1J, 100mW, 35J/cm{sup 2}, spot area of 0.028 cm{sup 2}). The third stage compared different strains of mice Balb-c and C57BL/6) in the best local and time parameters found in step 2. At all stages, we evaluated the change in paw volume by plethysmography and inflammatory infiltrate by histomorphometry or analysis of myeloperoxidase (MPO). The results showed that laser phototherapy treated and prevented edema and modulated the inflammatory process with paw and inguinal lymph nodes irradiations accordingly with the parameters and mice strain used. (author)

  17. Internal dosimetry, past and future

    International Nuclear Information System (INIS)

    Progress in the dosimetry of internally deposited radionuclides since World War II is reviewed. The Permissible Doses Conference held at Chalk River in 1949 defined the Standard Man and a biokinetic lung model, setting maximum permissible body burdens (MPBB), maximum permissible concentrations in air (MPCA), and maximum permissible concentrations in water (MPCW) for selected radionuclides. ICRP publications 2, 6 and 9 followed, focusing on setting MPCs. The use of the power function to describe radionuclide retention in the human body was discussed in Publication 2, but not recommended for use until Publication 6. Publication 2 defined the term effective energy. The integration time for internal exposures became 50 years, and the committed dose was defined. ICRP publications 10, 10A and 54 provided guidance for the calculation of doses from measured activity in vivo or in excreta. In 1979 ICRP publication 30 replaced publication 2 as the handbook for internal dosimetry. There will be a major revision of Publication 30 following the release of the new ICRP recommendations. A future publication will give doses to patients who have been administered radiopharmaceuticals. New computer tools will allow the development of more realistic metabolic models, and new dosimetric models that calculate doses to cells will be developed. The availability of high resolution solid state detectors has resulted in improvement in measurements of radionuclides in vivo, and some improvement in radiochemical analyses of excreta. However, poor sensitivity to actinides leaves something to be desired in vitro measurements and air monitoring

  18. Dosimetry effects of film packing

    International Nuclear Information System (INIS)

    Full text: Dosimetric artefacts in film based dosimetry have been addressed by a number of authors. We have investigated the influence on film dose results, of a number of materials that are commonly packed against the film including, solid water, paper, air and plastic. The results indicate that variations in optical density occur due to the character and relative quantity of the packing material as well as the film itself. Kodak X-omat V and GAFChromic film samples were placed in a solid water cassette with packing sheets of various materials placed in contact with the film. Photon and electron exposures were carried out with various film orientation and beam qualities. Results have been obtained for solid water, paper and air. An example of the relative change in film density as a function of depth due to four paper sheets packed adjacent to a film aligned with the central axis of a 6MV photon beam is shown. Other results indicate dose variation can be attributed to Cerenkov radiation. Packing materials in contact or in close proximity with dosimetric film, contribute to optical density variations of the order of several percent. Careful consideration of these effects is necessary when using film in high accuracy dosimetry. Copyright (2001) Australasian College of Physical Scientists and Engineers in Medicine

  19. Fast neutron dosimetry: Progress summary

    International Nuclear Information System (INIS)

    The purpose was to investigate the radiological physics and biology of very low energy photons derived from a 1-GeV electron synchrotron storage ring. An extensive beam line and irradiation apparatus was designed, developed, and constructed. Dosimetry measurements required invention and testing of a miniature absolute calorimeter and a cell irradiation fixture suitable for scanning exposures under computer control. Measurements of the kerma factors of oxygen, aluminum and silicon for 14-20 MeV neutrons. Custom designed miniature proportional counters of cylindrical symmetry were employed in these determinations. The oxygen kerma factor was found significantly lower than values calculated from microscopic cross sections. We also tested Mg and Fe walled conventional spherical counters. The direct neutron-counting gas interaction is significant enough for these counters that a correction is needed. We also investigated the application of Nuclear Magnetic Resonance spectroscopy to radiation dosimetry. Our purpose was to take advantage of recent development of very high-field magnets, complex RF-pulse techniques for solvent suppression, and improved spectral analysis techniques

  20. CT dosimetry and risk estimates

    International Nuclear Information System (INIS)

    Conventional approaches to CT dosimetry are inadequate because they fail to evaluate the risk to the patient. A risk related approach to CT dosimetry is developed which explicitly takes into account the non-uniform dose distribution in the body and the relative sensitivities of different organs and tissues. The principal radiological risks to patients undergoing CT examinations are the stochastic processes of carcinogenesis and genetic effects. Radiation risk estimates have been obtained for an EMI 5005 CT scanner by measuring the mean organ doses in a Rando phantom for CT studies on the head, chest, abdomen and pelvis. The application of these risk estimates to the population served by this CT scanner indicates that during the lifetime of the CT scanner, approximately 50,000 patients will undergo CT scanning and 60% will result in a positive diagnosis. The radiation detriment is estimated to be about 1 induced cancer and a negligible genetic effect. The radiation detriment is considerably smaller than the total detriment associated with contrast material used in 76% of the CT studies. (author)

  1. Health physics research reactor reference dosimetry

    International Nuclear Information System (INIS)

    Reference neutron dosimetry is developed for the Health Physics Research Reactor (HPRR) in the new operational configuration directly above its storage pit. This operational change was physically made early in CY 1985. The new reference dosimetry considered in this document is referred to as the 1986 HPRR reference dosimetry and it replaces any and all HPRR reference documents or papers issued prior to 1986. Reference dosimetry is developed for the unshielded HPRR as well as for the reactor with each of five different shield types and configurations. The reference dosimetry is presented in terms of three different dose and six different dose equivalent reporting conventions. These reporting conventions cover most of those in current use by dosimetrists worldwide. In addition to the reference neutron dosimetry, this document contains other useful dosimetry-related data for the HPRR in its new configuration. These data include dose-distance measurements and calculations, gamma dose measurements, neutron-to-gamma ratios, ''9-to-3 inch'' ratios, threshold detector unit measurements, 56-group neutron energy spectra, sulfur fluence measurements, and details concerning HPRR shields. 26 refs., 11 figs., 31 tabs

  2. Prophylactic cerebral irradiation in children with leukemia: In vivo evaluation of the irradiation dose applied to the thyroid during prophylactic cerebral irradiation delivered within the framework of the children leukemia treatment; Dosimetrie in vivo pour l`evaluation de la dose recue par la thyroide lors de l`irradiation cerebrale prophylactique delivree dans le cadre du traitement des leucemies de l`enfant

    Energy Technology Data Exchange (ETDEWEB)

    Ricardi, U.; Rossi, G.; Tessa, M.; Monetti, U.; Verna, R.; Urgesi, A.; Barisone, E.; Besenzon, L.; Corrias, A. [Turin Univ. (Italy)

    1997-09-01

    The aim of this work is to evaluate by in vivo dosimetry, the dose received by the thyroid parenchyma during an encephalon irradiation for children having acute lymphoid leukemia, then to look for a correlation between the thyroid alterations ( hypothyroidism, second tumors) and the dosimetry data. (N.C.). 5 refs.

  3. Electron paramagnetic resonance technique for radiation dosimetry: emerging trends for laboratory and accidental dosimetry

    International Nuclear Information System (INIS)

    The applications of Electron Paramagnetic Resonance (EPR) for radiation dosimetry are briefly reviewed. In particular, EPR-alanine dosimetry and accidental dosimetry using EPR signals from human tooth enamel have been discussed. The alanine dosimetry was found to be useful from low doses such as 1 Gy to high doses such as 100 kGy. The signals from tooth enamel are found to be invaluable in assessing the absorbed dose of people exposed to radiation accidents and also survivors of atomic bomb explosions. New emerging trends using EPR signals from bones exposed to radiation have also been briefly reviewed. (author)

  4. Theories about consensus-based conservation.

    Science.gov (United States)

    Leach, William D

    2006-04-01

    "Conservation and the Myth of Consensus" (Peterson et al. 2005) levels several serious indictments against consensus-based approaches to environmental decision making. Namely, the authors argue that consensus processes (1) reinforce apathy and ignorance of conservation issues; (2) legitimize damage to the environment; (3) quash public debate about conservation; (4) solidify the existing balance of power in favor of prodevelopment forces; and (5) block progress toward an ecologically sustainable future. Careful scrutiny of consensus-based approaches is important, especially considering their surging use in conservation policy. In the spirit of advancing the debate further, I review some of the limitations of the essay and its modes of inquiry.

  5. Learning consensus in adversarial environments

    Science.gov (United States)

    Vamvoudakis, Kyriakos G.; García Carrillo, Luis R.; Hespanha, João. P.

    2013-05-01

    This work presents a game theory-based consensus problem for leaderless multi-agent systems in the presence of adversarial inputs that are introducing disturbance to the dynamics. Given the presence of enemy components and the possibility of malicious cyber attacks compromising the security of networked teams, a position agreement must be reached by the networked mobile team based on environmental changes. The problem is addressed under a distributed decision making framework that is robust to possible cyber attacks, which has an advantage over centralized decision making in the sense that a decision maker is not required to access information from all the other decision makers. The proposed framework derives three tuning laws for every agent; one associated with the cost, one associated with the controller, and one with the adversarial input.

  6. Biological dosimetry - Dose estimation method using biomakers

    International Nuclear Information System (INIS)

    The individual radiation dose estimation is an important step in the radiation risk assessment. In case of radiation incident or radiation accident, sometime, physical dosimetry method can not be used for calculating the individual radiation dose, the other complement method such as biological dosimetry is very necessary. This method is based on the quantitative specific biomarkers induced by ionizing radiation, such as dicentric chromosomes, translocations, micronuclei... in human peripheral blood lymphocytes. The basis of the biological dosimetry method is the close relationship between the biomarkers and absorbed dose or dose rate; the effects of in vitro and in vivo are similar, so it is able to generate the calibration dose-effect curve in vitro for in vivo assessment. Possibilities and perspectives for performing biological dosimetry method in radiation protection area are presented in this report. (author)

  7. Alanine - ESR dosimetry, feasibility and possible applications

    International Nuclear Information System (INIS)

    Alanine ESR dosimetry presents a great interest for quality controls in radiotherapy. This new developed water equivalent alanine dosimeter allows a reproducible dose measurement, by a non-destructive readout technique in a large dose range. In this paper the stability of the dosimeter response has been shown but also its independence with the energy or the dose rate of the absorbed radiation. Through this different studies, one can broaden the application field of alanine / ESR dosimetry especially for in-vivo dosimetry. The results of the experiments and the intra operative treatment, indicate that this kind of dosimetry seems to be a promising technique for in-vivo quality controls in electron beam, γ ray or X ray radiotherapy. (authors)

  8. Advanced materials in radiation dosimetry

    CERN Document Server

    Bruzzi, M; Nava, F; Pini, S; Russo, S

    2002-01-01

    High band-gap semiconductor materials can represent good alternatives to silicon in relative dosimetry. Schottky diodes made with epitaxial n-type 4 H SiC and Chemical Vapor Deposited diamond films with ohmic contacts have been exposed to a sup 6 sup 0 Co gamma-source, 20 MeV electrons and 6 MV X photons from a linear accelerator to test the current response in on-line configuration in the dose range 0.1-10 Gy. The released charge as a function of the dose and the radiation-induced current as a function of the dose-rate are found to be linear. No priming effects have been observed using epitaxial SiC, due to the low density of lattice defects present in this material.

  9. Development of radiation biological dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Chul Koo; Kim, Tae Hwan; Lee, Yun Sil; Son, Young Sook; Kim, Soo Kwan; Jang, Won Suk; Le, Sun Joo; Jee, Young Heun; Jung, Woo Jung

    1999-04-01

    Up until now, only a few methods have been developed for radiation biological dosimetry such as conventional chromosome aberration and micronucleus in peripheral blood cell. However, because these methods not only can be estimated by the expert, but also have a little limitation due to need high technique and many times in the case of radiation accident, it is very difficult to evaluate the absorbed dose of victims. Therefore, we should develop effective, easy, simple and rapid biodosimetry and its guideline (triage) to be able to be treated the victims as fast as possible. We established the premature chromosome condensation assay and apoptotic fragment assay which was the significant relationship between dose and cell damages to evaluate the irradiation dose as correct and rapid as possible using lymphocytes and crypt cells, and compared with conventional chromosome aberration assay and micronuclei assay.

  10. Development of radiation biological dosimetry

    International Nuclear Information System (INIS)

    Up until now, only a few methods have been developed for radiation biological dosimetry such as conventional chromosome aberration and micronucleus in peripheral blood cell. However, because these methods not only can be estimated by the expert, but also have a little limitation due to need high technique and many times in the case of radiation accident, it is very difficult to evaluate the absorbed dose of victims. Therefore, we should develop effective, easy, simple and rapid biodosimetry and its guideline (triage) to be able to be treated the victims as fast as possible. We established the premature chromosome condensation assay and apoptotic fragment assay which was the significant relationship between dose and cell damages to evaluate the irradiation dose as correct and rapid as possible using lymphocytes and crypt cells, and compared with conventional chromosome aberration assay and micronuclei assay

  11. Audits for advanced treatment dosimetry

    International Nuclear Information System (INIS)

    Radiation therapy has advanced rapidly over the last few decades, progressing from 3D conformal treatment to image-guided intensity modulated therapy of several different flavors, both 3D and 4D and to adaptive radiotherapy. The use of intensity modulation has increased the complexity of quality assurance and essentially eliminated the physicist's ability to judge the validity of a treatment plan, even approximately, on the basis of appearance and experience. Instead, complex QA devices and procedures are required at the institutional level. Similarly, the assessment of treatment quality through remote and on-site audits also requires greater sophistication. The introduction of 3D and 4D dosimetry into external audit systems must follow, to enable quality assurance systems to perform meaningful and thorough audits

  12. Activities developed by the biological dosimetry laboratory of the Autoridad Regulatoria Nuclear - ARN of Argentina

    International Nuclear Information System (INIS)

    Biological dosimetry (DB) allows to estimate doses absorbed in individuals exposed to ionizing radiation through the quantification of stable and unstable chromosome aberrations (SCA and UCA). The frequency of these aberrations is referred to a calibration dose response curve (in vitro) to determine the doses of the individual to the whole body. The DB is a necessary support for programs of national radiation protection and response systems in nuclear or radiological emergencies in the event of accidental or incidental, single overexposure or large scale. In this context the Laboratory of Dosimetry Biological (LDB) of the Authority Regulatory Nuclear (ARN) Argentina develops and applies different dosimeters cytogenetic from four decades ago. These dosimeters provide a fact more within the whole of the information necessary for an accidental, complementing the physical and clinical dosimetry exposure assessment. The most widely used in the DB biodosimetric method is the quantification of SCA (dicentrics and rings Central) from a sample of venous blood. The LDB is accredited for the trial, under rules IRAM 301: 2005 (ISO / IEC 17025: 2005) and ISO 19238:2004. Test applies to the immediate dosimetry evaluation of acute exposures, all or a large part of the body in the range 0,1-5 Gy. In this context the LDB is part of the Latin American network of DB (LBDNet), BioDoseNet-who and response system in radiological emergencies and nuclear IAEA-RANET, being enabled to summon the LBDNet if necessary

  13. Application of radiation damage effects in dosimetry

    International Nuclear Information System (INIS)

    some general aspects of radiation dosimetry are outlined. The techniques of radiophotoluminescence, radiothermoluminescence and exo-electron emission are discussed individually. It is thought that the trend in personnel dosimetry is such that thermoluminescence will steadily replace film and photoluminescence techniques over the next decade, and that more unusual techniques, such as exo-electron emission, will make inroads only for special purposes. (B.R.H.)

  14. Developments in Patient Dosimetry for Unsealed Sources

    International Nuclear Information System (INIS)

    In molecular radiotherapy, treatment planning essentially is the determination of the activity to administer to optimize safety and efficacy of a treatment. Individualization is possible, for example, by using quantitative imaging modalities, external counting and blood sampling for pre-therapeutic biokinetics measurements. Patient specific dosimetry can be performed as in radiation therapy. Over- or under treatment of patients can be avoided. Here, the standard methods and the expected advances in performing individualized dosimetry are discussed. (author)

  15. Delay-Induced Consensus and Quasi-Consensus in Multi-Agent Dynamical Systems

    NARCIS (Netherlands)

    Yu, Wenwu; Chen, Guanrong; Cao, Ming; Ren, Wei

    2013-01-01

    This paper studies consensus and quasi-consensus in multi-agent dynamical systems. A linear consensus protocol in the second-order dynamics is designed where both the current and delayed position information is utilized. Time delay, in a common perspective, can induce periodic oscillations or even c

  16. Strategic consensus mapping : A new method for testing and visualizing strategic consensus within and between teams

    NARCIS (Netherlands)

    Tarakci, M.; Ates, N.Y.; Porck, J.P.; van Knippenberg, D.; Groenen, P.J.F.; de Haas, M.

    2014-01-01

    Research on strategic consensus focuses primarily on the extent of agreement among team members regarding organizational strategy. It does not include elements such as the content of the agreement, between-group consensus, or the significance of differences in consensus (e.g., for evaluating the eff

  17. Carotid endarterectomy: current consensus and controversies.

    Science.gov (United States)

    Meerwaldt, Robbert; Hermus, Linda; Reijnen, Michel M P J; Zeebregts, Clark J

    2010-10-01

    Stroke is the third most common cause of mortality, and carotid artery stenosis causes 8% to 29% of all ischemic strokes. Best medical treatment forms the basis of carotid stenosis treatment, and carotid endarterectomy (CEA) has an additional beneficial effect in high-grade stenosis. Carotid angioplasty and stenting (CAS) has challenged CEA as a primary carotid intervention. At present, CEA remains the gold standard, but in the future, CAS techniques will evolve and might become beneficial for subgroups of patients with carotid stenosis. This chapter briefly describes the history of carotid interventions and current consensus and controversies in CEA. In the last two years, several meta-analyses were published on a variety of aspects of best medical treatment, CEA, and CAS. It is still a matter of debate as to whether asymptomatic patients with carotid stenosis should undergo a carotid intervention. Especially because medical treatment has dramatically evolved since the early carotid trials. On the other hand, it is clear that carotid interventions in symptomatic patients with a high-grade stenosis should be performed as early as possible after the initial neurological event in order to achieve optimal stroke risk reduction. In CEA, the use of patching is advocated above primary closure, while the role of selective patching is still unclear. No differences in stroke and mortality rates are observed for routine versus selective shunting, for conventional versus eversion CEA, or for local versus general anesthesia. It is anticipated that in the future, there will be several interesting developments in carotid interventions such as plaque morphology analysis, acute interventions during stroke in progress, and further evolvement of CAS techniques.

  18. International Veterinary Epilepsy Task Force consensus proposal

    DEFF Research Database (Denmark)

    Bhatti, Sofie F M; De Risio, Luisa; Muñana, Karen;

    2015-01-01

    with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug...

  19. International veterinary epilepsy task force consensus proposal

    DEFF Research Database (Denmark)

    De Risio, Luisa; Bhatti, Sofie; Muñana, Karen;

    2015-01-01

    This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research settings. The diagnostic approach to the patient...

  20. Nordic consensus on treatment of undescended testes

    DEFF Research Database (Denmark)

    Ritzén, E Martin; Bergh, A; Bjerknes, R;

    2007-01-01

    To reach consensus among specialists from the Nordic countries on the present state-of-the-art in treatment of undescended testicles.......To reach consensus among specialists from the Nordic countries on the present state-of-the-art in treatment of undescended testicles....

  1. Bruxism defined and graded: an international consensus

    NARCIS (Netherlands)

    F. Lobbezoo; J. Ahlberg; A.G. Glaros; T. Kato; K. Koyano; G.J. Lavigne; R. de Leeuw; D. Manfredini; P. Svensson; E. Winocur

    2013-01-01

    To date, there is no consensus about the definition and diagnostic grading of bruxism. A written consensus discussion was held among an international group of bruxism experts as to formulate a definition of bruxism and to suggest a grading system for its operationalisation. The expert group defined

  2. Veto-Consensus Multiple Kernel Learning

    NARCIS (Netherlands)

    Y. Zhou; N. Hu; C.J. Spanos

    2016-01-01

    We propose Veto-Consensus Multiple Kernel Learning (VCMKL), a novel way of combining multiple kernels such that one class of samples is described by the logical intersection (consensus) of base kernelized decision rules, whereas the other classes by the union (veto) of their complements. The propose

  3. Consensus statement on genetic research in dementia

    DEFF Research Database (Denmark)

    Rikkert, M.G. Olde; der, V van; Burns, A.;

    2008-01-01

    procedure fuelled the development of the consensus statement, which is presented in this paper. The consensus statement aims to stimulate ethically acceptable research in the field of dementia and the protection of vulnerable elderly patients with dementia from application of inadequate research methods...

  4. Is acute recurrent pancreatitis a chronic disease?

    OpenAIRE

    Mariani, Alberto; Testoni, Pier Alberto

    2008-01-01

    Whether acute recurrent pancreatitis is a chronic disease is still debated and a consensus is not still reached as demonstrated by differences in the classification of acute recurrent pancreatitis. There is major evidence for considering alcoholic pancreatitis as a chronic disease ab initio while chronic pancreatitis lesions detectable in biliary acute recurrent pancreatitis (ARP) seem a casual association. Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation, hereditary a...

  5. Imaging based, patient specific dosimetry

    International Nuclear Information System (INIS)

    Full text: The prognosis of achieving longtime remission for disseminated cancer disease is in many cases poor. A systemic treatment is required and therefore external beam radiation therapy is less suited. Treatment with radiolabeled pharmaceuticals, so called radionuclide therapy is such a systemic treatment. In radionuclide therapy, the absorbed dose is delivered by administration of radionuclides that emit electrons or alpha particles. It is here assumed that the released kinetic energy is transferred by interactions to sensitive parts of the cells activating cell death, and thus an accurate dosimetry is important. However, absorbed dose planning for radionuclide therapy is a real challenge in that the source cannot be turned on or off (as in external beam therapy) but decays exponentially with characteristics depending on the biokinetics and the radionuclide half-life. On a small-scale, the radiopharmaceutical is also heterogeneously distributed which means that the energy deposition is generally nonuniform. The biokinetics may also change over time which means that activity measurements need to be made at several time points to estimate the total amount of released energy in an organ or tumour. Practical issues regarding the number of measurements and patient mobility may therefore limit the accuracy in this calculation. The dose-rate for radionuclide therapy is also much lower than in external beam therapy. Since the treatment is systemic, circulating activity may result in absorbed doses to normal organs and tissues. Often this poses a problem and puts a limit on the amount of activity to can be administered. This is one of the major reasons for the requirement of an accurate patient-specific dosimetry. One of the major problems is that the biokinetics varies between patients and the activity uptake and clearance should therefore be measured for each individual patient in order to estimate the total number of decays in a particular organ/tissue. The way

  6. Dosimetry and operation of irradiation facilities

    International Nuclear Information System (INIS)

    The industrial use of ionizing radiation has required, from the very first, the measurement of delivered and absorbed doses; hence the necessity of providing dosimetric systems. Laboratories, scientists, industries and potential equipment manufacturers have all collaborated in this new field of activity. Dosimetric intercomparisons have been made by each industry at their own facilities and in collaboration with specialists, national organizations and the IAEA. Dosimetry has become a way of ensuring that treatment by irradiation has been carried out in accordance with the rules. It has become in effect assurance of quality. Routine dosimetry should determine a maximum and minimum dose. Numerous factors play a part in dosimetry. Industry is currently in possession of routine dosimetric systems that are sufficiently accurate, fairly easy to handle and reasonable in cost, thereby satisfying all the requirements of industry and the need for control. Dosimetry is important in the process of marketing irradiated products. The operator of an industrial irradiation facility bases his dosimetry on comparison with reference systems. Research aimed at simplifying the practice of routine dosimetry should be continued. New physical and chemical techniques will be incorporated into systems already in use. The introduction of microcomputers into the operation of radiation facilities has increased the value of dosimetry and made the conditions of treatment more widespread. Stress should be placed on research in several areas apart from reference systems, for example: dosimetric systems at temperatures from +8 deg. C to -45 deg. C, over the dose range 100 krad to a little more than 1 Mrad, liquids and fluidized solids carried at high speed through ducts, thin-film liquids circulating at a high flow rate, and various other problems. (author)

  7. Dosimetry intercomparisons in European medical device sterilization plants

    DEFF Research Database (Denmark)

    Miller, A.; Sharpe, P.H.G.

    2000-01-01

    Dosimetry intercomparisons have been carried out involving two-thirds of all European radiation sterilization facilities. Dosimeters for the intercomparisons were supplied by two accredited calibration laboratories. The results show good agreement, and indicate overall dosimetry accuracy of the o...

  8. Sampled-Data Consensus Over Random Networks

    Science.gov (United States)

    Wu, Junfeng; Meng, Ziyang; Yang, Tao; Shi, Guodong; Johansson, Karl Henrik

    2016-09-01

    This paper considers the consensus problem for a network of nodes with random interactions and sampled-data control actions. We first show that consensus in expectation, in mean square, and almost surely are equivalent for a general random network model when the inter-sampling interval and network size satisfy a simple relation. The three types of consensus are shown to be simultaneously achieved over an independent or a Markovian random network defined on an underlying graph with a directed spanning tree. For both independent and Markovian random network models, necessary and sufficient conditions for mean-square consensus are derived in terms of the spectral radius of the corresponding state transition matrix. These conditions are then interpreted as the existence of critical value on the inter-sampling interval, below which global mean-square consensus is achieved and above which the system diverges in mean-square sense for some initial states. Finally, we establish an upper bound on the inter-sampling interval below which almost sure consensus is reached, and a lower bound on the inter-sampling interval above which almost sure divergence is reached. Some numerical simulations are given to validate the theoretical results and some discussions on the critical value of the inter-sampling intervals for the mean-square consensus are provided.

  9. Personnel neutron dosimetry at Department of Energy facilities

    Energy Technology Data Exchange (ETDEWEB)

    Brackenbush, L.W.; Endres, G.W.R.; Selby, J.M.; Vallario, E.J.

    1980-08-01

    This study assesses the state of personnel neutron dosimetry at DOE facilities. A survey of the personnel dosimetry systems in use at major DOE facilities was conducted, a literature search was made to determine recent advances in neutron dosimetry, and several dosimetry experts were interviewed. It was concluded that personnel neutron dosimeters do not meet current needs and that serious problems exist now and will increase in the future if neutron quality factors are increased and/or dose limits are lowered.

  10. Technical Basis Document for PFP Area Monitoring Dosimetry Program

    CERN Document Server

    Cooper, J R

    2000-01-01

    This document describes the phantom dosimetry used for the PFP Area Monitoring program and establishes the basis for the Plutonium Finishing Plant's (PFP) area monitoring dosimetry program in accordance with the following requirements: Title 10, Code of Federal Regulations (CFR), part 835, ''Occupational Radiation Protection'' Part 835.403; Hanford Site Radiological Control Manual (HSRCM-1), Part 514; HNF-PRO-382, Area Dosimetry Program; and PNL-MA-842, Hanford External Dosimetry Technical Basis Manual.

  11. Experimental verification of internal dosimetry calculations. Annual progress report

    International Nuclear Information System (INIS)

    During the past year a dosimetry research program has been established in the School of Nuclear Engineering at the Georgia Institute of Technology. The major objective of this program has been to provide research results upon which a useful internal dosimetry system could be based. The important application of this dosimetry system will be the experimental verification of internal dosimetry calculations such as those published by the MIRD Committee

  12. Personnel neutron dosimetry at Department of Energy facilities

    International Nuclear Information System (INIS)

    This study assesses the state of personnel neutron dosimetry at DOE facilities. A survey of the personnel dosimetry systems in use at major DOE facilities was conducted, a literature search was made to determine recent advances in neutron dosimetry, and several dosimetry experts were interviewed. It was concluded that personnel neutron dosimeters do not meet current needs and that serious problems exist now and will increase in the future if neutron quality factors are increased and/or dose limits are lowered

  13. Sixth personnel dosimetry intercomparison study

    International Nuclear Information System (INIS)

    The Sixth Personnel Dosimetry Intercomparison Study was conducted March 25 to 27, 1980, at the Oak Ridge National Laboratory. Dosimeters from 28 participating agencies were mounted on anthropomorphic phantoms and exposed to a range of low-level dose equivalents (1.8 to 11.5 mSv neutron, 0.1 to 1.1 mSv gamma) which could be encountered during routine personnel monitoring in mixed radiation fields. The Health Physics Research Reactor (HPRR) operated in the steady-state mode served as the source of radiation for six separate exposures. Lucite and concrete shields along with the unshielded reactor were used to provide three different neutron and gamma spectra. Results reported by the participating agencies showed that TLD-albedo and TLD-700 dosimeters generally provided the most accurate measurements of neutron and gamma dose equivalents, respectively. Film was found to be unsatisfactory for measuring neutron doses produced by HPRR spectra in that measured dose equivalents were much lower than reference values. The TLD-100 dosimeters yielded gamma doses which were much too high indicating that this dosimeter type is generally unsuitable for use in mixed radiation fields similar to those encountered in this study without the use of large correction factors. Although the overall reported results exhibited improvement in performance relative to previous intercomparison studies, the composite measured data showed variations of more than a factor of 2 between measurements of the same exposure made by different agencies

  14. Radiosynoviorthesis. Clinical and preclinical dosimetry

    International Nuclear Information System (INIS)

    Accurate calculation of internal dose estimates in the Radiosynoviorthesis treatment requires several steps of analysis. The use of animal models (rabbits) to predict human kinetics and dosimetry is an essential first step in the evaluation of new radiocolloids, but involves many uncertainties. There is no gold standard method for extrapolating animal data to humans. Nonetheless, human dose estimates based on animal data are considered to be reasonable approximations to be used for proceeding with dose estimates based on human data, which are ultimately used to assess the safety and efficacy evaluations of radiopharmaceuticals, and continues to be an important element in the radiopharmaceutical approval process. The obtained absorbed dose profiles versus synovial tissue, bone and articular cartilage depth will permit the specialist to prescribe the adequate dose of radionuclide to treat rheumatoid arthritis in medium and large joints without expose the healthy structures of the synovial joint to an excessive and unnecessary irradiation risk, eliminating the fixed dose and fixed radionuclides for each joints (Author)

  15. Randomized Binary Consensus with Faulty Agents

    Directory of Open Access Journals (Sweden)

    Alexander Gogolev

    2014-05-01

    Full Text Available This paper investigates self-organizing binary majority consensus disturbed by faulty nodes with random and persistent failure. We study consensus in ordered and random networks with noise, message loss and delays. Using computer simulations, we show that: (1 explicit randomization by noise, message loss and topology can increase robustness towards faulty nodes; (2 commonly-used faulty nodes with random failure inhibit consensus less than faulty nodes with persistent failure; and (3 in some cases, such randomly failing faulty nodes can even promote agreement.

  16. Dosimetry in radiation processing- Indian scenario

    International Nuclear Information System (INIS)

    Radiation processing is a method for producing chemical, physical, and microbiological changes in substances by exposing to ionizing radiation. Availability of high intensity cobalt-60 gamma ray sources and high power electron beam accelerators has led to a continuous growth of radiation processing industry in India. Commercial viability and safe operation of these radiation-processing plants depends on accurate dosimetry. Depending on the purpose to be achieved, a widespread dose range, from few grays to few hundred kilo grays, is encountered in radiation processing technology and this necessitates the use of different dosimetry systems. In the present paper, current status of radiation processing facilities in India has been reviewed. Various indigenously developed dosimetry systems such as Alanine/glutamine (Spectrophotometric readout), FBX and ceric-cerous (potentiometry) are being used for quality assurance and routine plant dosimetry. Fricke dosimeter is used as a reference standard for calibrating other dosimetry systems. Glutamine (Spectrophotometric read out) dosimeter, used as transfer standard for Q.A. has traceability to NPL, UK and has shown an agreement within ±2% during dose intercomparisons carried out with various international standards laboratories. Performance of these dosimeters was found to be better than ±10% during dose measurements in radiation sterilization and food irradiation plants. (author)

  17. 10 CFR 835.1304 - Nuclear accident dosimetry.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Nuclear accident dosimetry. 835.1304 Section 835.1304... Nuclear accident dosimetry. (a) Installations possessing sufficient quantities of fissile material to... nuclear accident is possible, shall provide nuclear accident dosimetry for those individuals. (b)...

  18. Dosimetry methods for fuels, cladding and structural materials

    International Nuclear Information System (INIS)

    This volume of the proceedings of the symposium on reactor dosimetry covers the following topics: the metallurgy and dosimetry interface, radiation damage correlations of structural materials and damage analyses techniques, dosimetry for fusion materials, light water reactor pressure vessel surveillance in practice and irradiation experiments, fast reactor and reseach reactor characterization

  19. SEVENTH DOE WORKSHOP ON PERSONNEL NEUTRON DOSIMETRY

    Energy Technology Data Exchange (ETDEWEB)

    Vallario, E J

    1978-10-24

    This workshop was the seventh of a series and was held on October 23-24. 1978, at the Central Electricity Generating Board, HQ, London, England. Typically~ attendees at the Workshop were concerned with one of three activities: studying and refining existing techniques in an attempt to quantify already-known parameters with greater precision, looking for ways to apply existing neutron dosirr:etry techniques to a specific local problem, identifying the needs and weaknesses of existing systems, with the goal of improving and passibly simplifying field measurements. The types of neutron dosimetry techniques discussed by participants included albedo dosimeters, track etch, and TLD. One speaker reported on NTA film, noting that fading could be eliminated by drying the emulsion in dry nitrogen before field use. There were no reports on tissue equivalent proportional counters or activation analysis. One participant discussed a metal oxide silicon dosimeter. The need to develop a consistent standard terminology, as well as calibration sources and techniques, on both the national and international level was evident. The need for standardization is particularly acute in the U.S. Techniques for evaluating dosimeter response in the field should he standardized, since several different instruments with widely different response characteristics are currently being used. The choice of instruments is often parochial. Also. the type and use of phantoms should be standardized. Neutron dose assignment is significantly affected by the position of the dosimeter on the body. for example, a typical albedo dosimeter may give differences of up to 20% depending on whether it is worn on the belt or chest. Larger errors are encountered with front-to-back (angular} orientation. 1n an attempt to minimize such errors~ at least two European facilities are using neutron dosimeter belts, which provide dosimeters both in front and in back of the wearer. The gamma-to-neutron ratio around nuclear power

  20. Bayesian Methods for Radiation Detection and Dosimetry

    CERN Document Server

    Groer, Peter G

    2002-01-01

    We performed work in three areas: radiation detection, external and internal radiation dosimetry. In radiation detection we developed Bayesian techniques to estimate the net activity of high and low activity radioactive samples. These techniques have the advantage that the remaining uncertainty about the net activity is described by probability densities. Graphs of the densities show the uncertainty in pictorial form. Figure 1 below demonstrates this point. We applied stochastic processes for a method to obtain Bayesian estimates of 222Rn-daughter products from observed counting rates. In external radiation dosimetry we studied and developed Bayesian methods to estimate radiation doses to an individual with radiation induced chromosome aberrations. We analyzed chromosome aberrations after exposure to gammas and neutrons and developed a method for dose-estimation after criticality accidents. The research in internal radiation dosimetry focused on parameter estimation for compartmental models from observed comp...

  1. Performance testing of UK personal dosimetry laboratories

    CERN Document Server

    Marshall, T O

    1985-01-01

    The proposed Ionising Radiations Regulations will require all UK personal dosimetry laboratories that monitor classified personnel to be approved for personal dosimetry by the Health and Safety Executive. It is suggested that these approvals should be based on general and supplementary criteria published by the British Calibration Service (BCS) for laboratory approval for the provision of personal dosimetry services. These criteria specify certain qualitative requirements and also indicate the need for regular tests of performance to be carried out to ensure constancy of dosimetric standards. This report concerns the latter. The status of the BCS criteria is discussed and the need for additional documents to cover new techniques and some modifications to existing documents is indicated. A means is described by which the technical performance of laboratories, concerned with personal monitoring for external radiations, can be assessed, both initially and ongoing. The costs to establish the scheme and operate it...

  2. Model selection for radiochromic film dosimetry

    CERN Document Server

    Méndez, Ignasi

    2015-01-01

    The purpose of this study was to find the most accurate model for radiochromic film dosimetry by comparing different channel independent perturbation models. A model selection approach based on (algorithmic) information theory was followed, and the results were validated using gamma-index analysis on a set of benchmark test cases. Several questions were addressed: (a) whether incorporating the information of the non-irradiated film, by scanning prior to irradiation, improves the results; (b) whether lateral corrections are necessary when using multichannel models; (c) whether multichannel dosimetry produces better results than single-channel dosimetry; (d) which multichannel perturbation model provides more accurate film doses. It was found that scanning prior to irradiation and applying lateral corrections improved the accuracy of the results. For some perturbation models, increasing the number of color channels did not result in more accurate film doses. Employing Truncated Normal perturbations was found to...

  3. Reference dosimetry and measurement quality assurance

    International Nuclear Information System (INIS)

    Measurements of absorbed dose made by a reference dosimetry system, such as alanine, have been suggested for achieving quality assurance through traceability to primary standards. Such traceability can assist users of radiation worldwide in enhancing quality control in medicine, agriculture, and industry. International and national standards of absorbed dose are still needed for applications of γ-ray and electron dosimetry at high doses (e.g. radiation therapy, food irradiation and industrial radiation processing). Reference systems, such as ferrous sulfate dosimeters measured by spectrophotometry and alanine measured by electron spin resonance spectrometry are already well established. Another useful reference system for high doses is supplied as dichromate solutions measured by spectrophotometry. Reference dosimetry, particularly for electron beams, can be accomplished with thin alanine or radiochromic dye film dosemeters. (author)

  4. Dosimetry procedures for an industrial irradiation plant

    Science.gov (United States)

    Grahn, Ch.

    Accurate and reliable dosimetry procedures constitute a very important part of process control and quality assurance at a radiation processing plant. γ-Dose measurements were made on the GBS 84 irradiator for food and other products on pallets or in containers. Chemical dosimeters wre exposed in the facility under conditions of the typical plant operation. The choice of the dosimeter systems employed was based on the experience in chemical dosimetry gained over several years. Dose uniformity information was obtained in air, spices, bulbs, feeds, cosmetics, plastics and surgical goods. Most products currently irradiated require dose uniformity which can be efficiently provided by pallet or box irradiators like GBS 84. The radiation performance characteristics and some dosimetry procedures are discussed.

  5. A dynamic dosimetry system for prostate brachytherapy

    Science.gov (United States)

    Kuo, Nathanael; Dehghan, Ehsan; Deguet, Anton; Song, Danny Y.; Prince, Jerry L.; Lee, Junghoon

    2013-03-01

    The lack of dynamic dosimetry tools for permanent prostate brachytherapy causes otherwise avoidable problems in prostate cancer patient care. The goal of this work is to satisfy this need in a readily adoptable manner. Using the ubiquitous ultrasound scanner and mobile non-isocentric C-arm, we show that dynamic dosimetry is now possible with only the addition of an arbitrarily configured marker-based fiducial. Not only is the system easily configured from accessible hardware, but it is also simple and convenient, requiring little training from technicians. Furthermore, the proposed system is built upon robust algorithms of seed segmentation, fiducial detection, seed reconstruction, and image registration. All individual steps of the pipeline have been thoroughly tested, and the system as a whole has been validated on a study of 25 patients. The system has shown excellent results of accurately computing dose, and does so with minimal manual intervention, therefore showing promise for widespread adoption of dynamic dosimetry.

  6. Radiation dosimetry activities in the Netherlands

    International Nuclear Information System (INIS)

    The Netherlands Commission for Radiation Dosimetry (NCS) was officially established on 3 September 1982 with the aim of promoting the appropriate use of dosimetry of ionizing radiation both for scientific research and practical applications. The present report provides a compilation of the dosimetry acitivities and expertise available in the Netherlands, based on the replies to a questionnaire mailed under the auspices of the NCS and might suffer from some incompleteness in specific details. The addresses of the Dutch groups with the names of the scientists are given. Individual scientists, not connected with a scientific group, hospital or organization have not been included in this list. Also the names of commercial firms producing dosimetric systems have been omitted. (Auth.)

  7. Survey of international personnel radiation dosimetry programs

    International Nuclear Information System (INIS)

    In September of 1983, a mail survey was conducted to determine the status of external personnel gamma and neutron radiation dosimetry programs at international agencies. A total of 130 agencies participated in this study including military, regulatory, university, hospital, laboratory, and utility facilities. Information concerning basic dosimeter types, calibration sources, calibration phantoms, corrections to dosimeter responses, evaluating agencies, dose equivalent reporting conventions, ranges of typical or expected dose equivalents, and degree of satisfaction with existing systems was obtained for the gamma and neutron personnel monitoring programs at responding agencies. Results of this survey indicate that to provide the best possible occupational radiation monitoring programs and to improve dosimetry accuracy in performance studies, facility dosimetrists, regulatory and standards agencies, and research laboratories must act within their areas of responsibility to become familiar with their radiation monitoring systems, establish common reporting guidelines and performance standards, and provide opportunities for dosimetry testing and evaluation. 14 references, 10 tables

  8. Instrumentation for the individual dosimetry of workers

    CERN Document Server

    Thévenin, J C

    2003-01-01

    The control of the radiation dose exposure of workers and personnel exposed to ionizing radiations (nuclear industry, nuclear medicine, army, university laboratories etc..) is ensured by individual dosemeters. This dosimetry is mandatory for all workers susceptible to be exposed to more than 30% of the regulatory dose limit. dosemeters are worn on the chest and in some particular cases, on the finger (dosemeter rings) or on the wrist. Passive dosemeters allow to measure the dose a posteriori, while electronic dosemeters allow a direct reading and recording of the dose. This article presents successively: 1 - the general principles of individual dosimetry: situations of exposure, radiation detection, operational data, standardization, calibration and quality assurance, measurement uncertainties; 2 - goals and regulatory framework of individual dosimetry: regulation and recommendations, optimization, respect of dose limits, accidental situations; 3 - passive dosemeters: film, thermoluminescent, radio-photolumin...

  9. OGC Consensus: How Successful Standards Are Made

    Directory of Open Access Journals (Sweden)

    Carl Reed

    2015-09-01

    Full Text Available This paper describes the history, background, and current status of the Open Geospatial Consortium (OGC standards development consensus process. The roots of the formation of the OGC lie in the early 1990s when a very strong market requirement for exchanging GIS data content was clearly stated. At that time, each GIS vendor had their own formats for publishing and/or exchanging their GIS data. There was no mechanism or organization that provided a forum for the GIS vendors and GIS data users to collaborate and agree on how to share GIS data. That requirement, along with the vision of a few individuals, led to the formation of the OGC. This paper describes the early development of the consensus process in the OGC, how this process has evolved over time, why consensus is so important for defining open standards that are implemented in the marketplace, and the future of the OGC consensus process.

  10. Improve consensus via decentralized predictive mechanisms

    Science.gov (United States)

    Zhang, H.-T.; Chen, M. Z. Q.; Zhou, T.

    2009-05-01

    For biogroups and groups of self-driven agents, making decisions often depends on interactions among group members. In this paper, we seek to understand the fundamental predictive mechanisms used by group members in order to perform such coordinated behaviors. In particular, we show that the future dynamics of each node in the network can be predicted solely using local information provided by its neighbors. Using this predicted future dynamics information, we propose a decentralized predictive consensus protocol, which yields drastic improvements in terms of both consensus speed and internal communication cost. In natural science, this study provides an evidence for the idea that some decentralized predictive mechanisms may exist in widely-spread biological swarms/flocks. From the industrial point of view, incorporation of a decentralized predictive mechanism allows for not only a significant increase in the speed of convergence towards consensus but also a reduction in the communication energy required to achieve a predefined consensus performance.

  11. Distributed Detection via Bayesian Updates and Consensus

    CERN Document Server

    Liu, Qipeng; Wang, Xiaofan

    2014-01-01

    In this paper, we discuss a class of distributed detection algorithms which can be viewed as implementations of Bayes' law in distributed settings. Some of the algorithms are proposed in the literature most recently, and others are first developed in this paper. The common feature of these algorithms is that they all combine (i) certain kinds of consensus protocols with (ii) Bayesian updates. They are different mainly in the aspect of the type of consensus protocol and the order of the two operations. After discussing their similarities and differences, we compare these distributed algorithms by numerical examples. We focus on the rate at which these algorithms detect the underlying true state of an object. We find that (a) The algorithms with consensus via geometric average is more efficient than that via arithmetic average; (b) The order of consensus aggregation and Bayesian update does not apparently influence the performance of the algorithms; (c) The existence of communication delay dramatically slows do...

  12. Individual dosimetry of workers and patients: implementation and perspectives

    International Nuclear Information System (INIS)

    These days organised by the section of the technical protection of the S.F.R.P. review the different techniques of dosimetry used in France and Europe, and present the future orientations.The different interventions are as follow: Individual exposures of the workers: historic assessment and perspectives; medical exposure: where are the doses; legal obligations in individual dosimetry: which are the objective and the need on the subject; the dosimetry follow-up of workers by the S.I.S.E.R.I. system: assessment and perspectives; impact of the norm ISO 20553 on the follow-up of internal exposure; the implementation of the patient dose measurement in Belgium; techniques of passive dosimetry used in Europe; Supervision radiation protection at EDF: long term and short term approach; Comparison active and passive dosimetry at Melox; methodology for the choice of new neutron dosemeters; the working group M.E.D.O.R.: guide of internal dosimetry for the use of practitioners; O.E.D.I.P.E.: tool of modeling for the personalized internal dosimetry; the use of the Monte-Carlo method for the planning of the cancer treatment by radiotherapy becomes a reality; the works of the committee 2 of the ICRP; passive dosimetry versus operational dosimetry: situation in Europe; Implementation of the in vivo dosimetry in a radiotherapy department: experience of the Gustave Roussy institute; experience feedback on the in vivo measures in radiotherapy, based on the use of O.S.L. pellets; multi points O.S.L. instrumentation for the radiation dose monitoring in radiotherapy; dosimetry for extremities for medical applications: principle results of the European contract C.O.N.R.A.D.; references and perspectives in dosimetry; what perspectives for numerical dosimetry, an example: Sievert; system of dose management: how to answer to needs; the last technical evolutions in terms of electronic dosimetry in nuclear power plant; the fourth generation type reactors: what dosimetry. (N.C.)

  13. HSE performance tests for dosimetry services

    International Nuclear Information System (INIS)

    In the United Kingdom a dosimetry service that measures and assesses whole-body or part-body doses arising from external radiation must successfully complete a performance test. Results of the performance tests for routine whole-body, routine extremity/skin and special accident dosimetry, carried out over the past six years by the AEA Technology Calibration Service at Winfrith, and DRaStaC, the AWE Calibration Service at Aldermaston, are presented. The test involves irradiating groups of dosemeters to known doses of gamma radiation and determining the bias and relative standard deviations for each dose group. The results are compared with the pass criteria specified by the UK Health and Safety Executive. For routine whole-body dosimetry, both the film badge and thermoluminescent dosemeter (TLD) perform adequately for irradiations between 0.6 and 30 mSv. For higher doses up to 250 mSv, where the slow emulsion of the film is used, the film badge shows poorer performance with a tendency to overestimate the dose. For routine extremity/skin dosimetry there is a wider spread of relative standard deviation results than is seen for routine whole-body dosimetry. This is to be expected since the results will include dosemeters that are based on 'disposable' TLDs and ones based on lithium fluoride powder in sachets. For special accident dosimetry the dosemeters are tested between 0.26 and 6 Gy. For the highest dose group the film badge invariably underestimates the true dose, whereas the TLD has a tendency to overestimate it. (author)

  14. Population conference: consensus and conflict.

    Science.gov (United States)

    Willson, P D

    1984-01-01

    The United Nations-sponsored International Conference on Population held in Mexico City was both a rejection and an affirmation of a new policy of the Reagan administration. The policy denies international family planning funds to nongovernmental organizations that perform or actively promote abortion as a family planning method in other nations. A compromise statement was accepted urging governments to take appropriate measures to discourage abortion as a family planning method and when possible to provide for the humane treatment and counseling of women ho resorted to abortion. The statement on abortion was 1 of 88 reccomendations approved by the conference. The commitment expressed in the 10-year-old World Population Plan of Action to the rights and responsiblity to all people as reaffirmed. The conference also endorsed family life education and sex education as well as suitable family planning, information and services for adolescents, with due consideration given to the role, rights and obligations of parents. Increased support for international population and family planning programs was urged and World Bank President, Clausen, urged a 4-fold increase in international funding by the year 2000. Most of the conference's recommendations re devoted to the broad range of population policy issues, including morbidity and mortality, international and internal migration, the relationship between population and economic development and the status of women. The purpose of the recommendations is to increase the momentum of international support. The Mexico City conference was characterized by a remarkable degree of consensus about population policies with respect to integration with economic development, the need to respect individual rights and the recognition that all nations have sovereign rights to develop and implement their own population policies. Conflict and controversy arose in the areas of the arms race and the Middle East. The US position on abortion funding

  15. Pragmatism and Political Pluralism - Consensus and Pluralism

    Directory of Open Access Journals (Sweden)

    Michele Marsonet

    2015-07-01

    In our day the German philosopher Jürgen Habermas has in a way revived these Peircean insights, putting forward an influential theory to the effect that consensus indeed plays a key role in human praxis, so that the primary task of philosophy is to foster it by eliminating the disagreement which we constantly have to face in the course of our daily life. In his “communicative theory of consensus,” furthermore, he claims that human communication rests on an implicit commitment to a sort of “ideal speech situation” which is the normative foundation of agreement in linguistic matters. Consequently, the quest for consensus is a constitutive feature of our nature of (rational human beings: rationality and consensus are tied together. A very strong consequence derives from Habermas’ premises: were we to abandon the search for consensus we would lose rationality, too, and this makes us understand that he views the pursuit of consensus as a regulative principle (rather than as a merely practical objective. Rescher opposes both Peirce’s eschatological view and Habermas’ regulative and idealized one.

  16. Technical basis for internal dosimetry at Hanford

    Energy Technology Data Exchange (ETDEWEB)

    Sula, M.J.; Carbaugh, E.H.; Bihl, D.E.

    1989-04-01

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products (/sup 58/Co, /sup 60/Co, /sup 54/Mn, and /sup 59/Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation; and bioassay follow-up treatment. 64 refs., 42 figs., 118 tabs.

  17. Dosimetry of Low-Energy Beta Radiation

    DEFF Research Database (Denmark)

    Borg, Jette

    Useful techniques and procedures for derermination of absorbed doses from exposure in a low-energy beta radiation were studied and evaluated. The four techniques included were beta spectrometry, extrapolation chamber dosimetry, Monte Carlo (MC) calculations, and exoelectron dosimetry. As a typical...... low-energy beta radiation field a moderated spectrum from a carbon-14 source was used. The measured responce of a Si(Li) detector to photons (bremsstrahlung) showed fine agreemant with the MC calculated photon response, whereas the difference between measured and MC calculated response to electrons...

  18. Technical basis for internal dosimetry at Hanford

    Energy Technology Data Exchange (ETDEWEB)

    Sula, M.J.; Carbaugh, E.H.; Bihl, D.E.

    1991-07-01

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products ({sup 58}Co, {sup 60}Co, {sup 54}Mn, and {sup 59}Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium,. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation and bioassay follow-up treatment. 78 refs., 35 figs., 115 tabs.

  19. Role of dosimetry in quality control

    International Nuclear Information System (INIS)

    Dosimetry plays an important role in the quality control of radiation processing. Increasingly, quality control systems are based on the standards in the 9000 series from the International Organization for Standardization, ISO. This is true not only in radiation sterilization but also in food treatment, polymer modification and other uses of radiation. It is required that all measurements - including radiation measurements -are traceable to national standards, and the uncertainty of the measurements must be stated with appropriate confidence limits. The paper discusses the significance of dosimetry, the evaluation of uncertainty, and the way in which traceability may be obtained. (author). 11 refs, 2 tabs

  20. Technical basis for internal dosimetry at Hanford

    International Nuclear Information System (INIS)

    The Hanford Internal Dosimetry Program, administered by Pacific Northwest Laboratory for the US Department of Energy, provides routine bioassay monitoring for employees who are potentially exposed to radionuclides in the workplace. This report presents the technical basis for routine bioassay monitoring and the assessment of internal dose at Hanford. The radionuclides of concern include tritium, corrosion products (58Co, 60Co, 54Mn, and 59Fe), strontium, cesium, iodine, europium, uranium, plutonium, and americium. Sections on each of these radionuclides discuss the sources and characteristics; dosimetry; bioassay measurements and monitoring; dose measurement, assessment, and mitigation; and bioassay follow-up treatment. 64 refs., 42 figs., 118 tabs

  1. Third conference on radiation protection and dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This conference has been designed with the objectives of promoting communication among applied, research, regulatory, and standards personnel involved in radiation protection and providing them with sufficient information to evaluate their programs. To partly fulfill these objectives, a technical program consisting of more than 75 invited and contributed oral presentations encompassing all aspects of radiation protection has been prepared. General topics include external dosimetry, internal dosimetry, instruments, regulations and standards, accreditation and test programs, research advances, and applied program experience. This publication provides a summary of the technical program and a collection of abstracts of the oral presentations.

  2. Third conference on radiation protection and dosimetry

    International Nuclear Information System (INIS)

    This conference has been designed with the objectives of promoting communication among applied, research, regulatory, and standards personnel involved in radiation protection and providing them with sufficient information to evaluate their programs. To partly fulfill these objectives, a technical program consisting of more than 75 invited and contributed oral presentations encompassing all aspects of radiation protection has been prepared. General topics include external dosimetry, internal dosimetry, instruments, regulations and standards, accreditation and test programs, research advances, and applied program experience. This publication provides a summary of the technical program and a collection of abstracts of the oral presentations

  3. Automation at NRCN Dosimetry Laboratory

    International Nuclear Information System (INIS)

    Running a dosimetric service based on TLD technology such as at the Nuclear Research Centre Negev (NRCN) requires a large group of workers to carry out simple mechanical actions such as opening and closing TLD badges, placing and removal of TLD cards from the badges and operating the TLD reader. These actions can be automated to free human resources for other assignments and to improve the quality assurance. At NRCN a project was undertaken to design and build a robotic system based on a manipulator arm. The design was based on the experience achieved with an earlier prototype (1,2). The system stores the TLD badges in special designed boxes, which are transported and stored in computer defined bins. The robotic arm loads and unloads TLD cards to the badges, and loads/unloads the cards to a magazine for the TLD reader. At the Nuclear Research Center Negev (NRCN) each badge is assigned to a specific worker and bears a sticker containing the worker's personal details, also in a machine readable form (barcode). In order to establish a proper QA check, a barcode reader records the information on the badge and on the TLD card placed in this badge and checks their compatibility with the information contained in the main database. Besides the TLD cards loading/unloading station, there is a contamination check station, a cards cleaning station and a UV irradiation box used to reduce the history dependent residual dose. The system was installed at the NRCN dosimetry laboratory It was successfully tested for several hundreds of cycles and will become operational in the first quarter of 2014. As far as we know, there is no similar product available for automatic handling in a TLD laboratory

  4. Kinetics model for lutate dosimetry

    International Nuclear Information System (INIS)

    The use of compartmental analysis to predict the behavior of drugs in the organism is considered the better option among numerous methods employed in pharmacodynamics. A six compartments model was developed to determinate the kinetic constants of 177Lu-DOTATATO biodistribution using data from one published study with 67 patients treated by PRRT (Peptide receptor radionuclide therapy) and followed by CT during 68,25 hours. The compartmental analysis was made using the software AnaComp®. The influence of the time pos-injection over the dose assessment was studied taking into account the renal excretion management by aminoacid coinfusion, whose direct effects persist in the first day. The biodistribution curve was split in five sectors: 0-0.25h; 0-3.25h; 3.25-24.25h; 24.25-68.25h and 3.25-68.25h. After the examination of that influence, the study was concentrated in separate the biodistribution curve in two phases. Phase 1: governed by uptake from the blood, considering the time pos-injection until 3.25h and phase 2: governed by renal excretion, considering the time pos-injection from 3.25h to 68.25h. The model considered the organs and tissues superposition in the CT image acquisition by sampling parameters as the contribution of the the activity concentration in blood and relation between the sizes of the whole body and measured organs. The kinetic constants obtained from each phase (1 and 2) were used in dose assessment to patients in 26 organs and tissues described by MIRD. Dosimetry results were in agreement with the available results from literature, restrict to whole body, kidneys, bone marrow, spleen and liver. The advantage of the proposed model is the compartmental method quickness and power to estimate dose in organs and tissues, including tumor that, in the most part, were not discriminate by voxels of phantoms built using CT images. (author)

  5. Dosimetry in intravascular brachytherapy; Calculos dosimetricos em braquiterapia intravascular

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Laelia Pumilla Botelho

    2000-03-01

    Among the cardiovascular diseases responsible for deaths in the adult population in almost all countries of the world, the most common is acute myocardial infarction, which generally occurs because of the occlusion of one or more coronary arteries. Several diagnostic techniques and therapies are being tested for the treatment of coronary artery disease. Balloon angioplasty has been a popular treatment which is less invasive than traditional surgeries involving revascularization of the myocardium, thus promising a better quality of life for patients. Unfortunately, the rate of restenosis (re-closing of the vessel) after balloon angioplasty is high (approximately 30-50% within the first year after treatment).Recently, the idea of delivering high radiation doses to coronary arteries to avoid or delay restenosis has been suggested. Known as intravascular brachytherapy, the technique has been used with several radiation sources, and researchers have obtained success in decreasing the rate of restenosis in some patient populations. In order to study the radiation dosimetry in the patient and radiological protection for the attending staff for this therapy, radiation dose distributions for monoenergetic electrons and photons (at nine discrete energies) were calculated for blood vessels of diameter 0.15, o,30 and 0.45 cm with balloon and wire sources using the radiation transport code MCNP4B. Specific calculations were carried out for several candidate radionuclides as well. Two s tent sources (metallic prosthesis that put inside of patient's artery through angioplasty) employing {sup 32} P are also simulated. Advantages and disadvantages of the various radionuclides and source geometries are discussed. The dosimetry developed here will aid in the realization of the benefits obtained in patients for this promising new technology. (author)

  6. [Kawasaki disease: interdisciplinary and intersocieties consensus (clinical guidelines). Brief version].

    Science.gov (United States)

    2016-08-01

    Kawasaki disease is an acute self-limiting systemic vasculitis. It is the most common cause of acquired heart disease, with the risk of developing coronary artery aneurysms, myocardial infarction and sudden death. Diagnosis is based on the presence of fever in addition to other clinical criteria. The quarter of the Kawasaki disease patients have "incomplete" presentation. Treatment with intravenous immunoglobulin within ten days of fever onset improves clinical outcomes and reduces the incidence of coronary artery dilation to less than 5%. Non-responders to standard therapy have shown a successful response with the use of corticosteroids and/or biological agents. The long-term management must be delineated according to the degree of coronary involvement in a multidisciplinary manner. To facilitate the pediatrician's diagnosis, treatment and monitoring of Kawasaki disease, a group of experts from the Argentine Society of Pediatrics and the Argentine Society of Cardiology carried out a consensus to develop practical clinical guidelines.

  7. [Kawasaki disease: interdisciplinary and intersocieties consensus (clinical guidelines). Brief version].

    Science.gov (United States)

    2016-08-01

    Kawasaki disease is an acute self-limiting systemic vasculitis. It is the most common cause of acquired heart disease, with the risk of developing coronary artery aneurysms, myocardial infarction and sudden death. Diagnosis is based on the presence of fever in addition to other clinical criteria. The quarter of the Kawasaki disease patients have "incomplete" presentation. Treatment with intravenous immunoglobulin within ten days of fever onset improves clinical outcomes and reduces the incidence of coronary artery dilation to less than 5%. Non-responders to standard therapy have shown a successful response with the use of corticosteroids and/or biological agents. The long-term management must be delineated according to the degree of coronary involvement in a multidisciplinary manner. To facilitate the pediatrician's diagnosis, treatment and monitoring of Kawasaki disease, a group of experts from the Argentine Society of Pediatrics and the Argentine Society of Cardiology carried out a consensus to develop practical clinical guidelines. PMID:27399018

  8. IOC consensus paper on the use of platelet-rich plasma in sports medicine

    OpenAIRE

    Engebretsen, Lars; Steffen, Kathrin; Alsousou, Joseph; Anitua, Eduardo; Bachl, Norbert; Everts, Peter; Hamilton, Bruce; Huard, Johnny; Jenoure, Peter; Kelberine, Francois; Kon, Elizaveta; Maffulli, Nicola; Matheson, Gordon; Mei-Dan, Omer; MENETREY, Jacques

    2010-01-01

    Acute and chronic musculoskeletal injuries in sports are common and problematic for both athletes and clinicians. A significant proportion of these injuries remain difficult to treat, and many athletes suffer from decreased performance and longstanding pain and discomfort. In 2008, the International Olympic Committee (IOC) published a consensus document on the importance of molecular mechanisms in connective tissue and skeletal muscle injury and healing. This document predicted an increase in...

  9. Dosimetry implant for treating restenosis and hyperplasia

    Science.gov (United States)

    Srivastava, Suresh; Gonzales, Gilbert R; Howell, Roger W; Bolch, Wesley E; Adzic, Radoslav

    2014-09-16

    The present invention discloses a method of selectively providing radiation dosimetry to a subject in need of such treatment. The radiation is applied by an implant comprising a body member and .sup.117mSn electroplated at selected locations of the body member, emitting conversion electrons absorbed immediately adjacent selected locations while not affecting surrounding tissue outside of the immediately adjacent area.

  10. A history of medical internal dosimetry

    International Nuclear Information System (INIS)

    This paper presents a short history of the development of medical dosimetry. It reviews the evaluation of the equations and discusses the development of various mathematical models used to improve radiation absorbed dose estimates. The contributions of Leonides Marinelli, Edith Qulmby, William Mayneord, Robert Loevinger, Walter Snyder, and others are emphasized. (author), 74 Refs., 7 Figs., 3 Tabs

  11. Dosimetry for the MR-linac

    NARCIS (Netherlands)

    Smit, K.

    2015-01-01

    The purpose of this thesis is to investigate the inuence of the MR scanner on dosimetry for the radiation modality, and to investigate the possible solutions for the dosimetric measurements discussed in section 1.7. Chapter 2 investigates the feasibility to use a standardized national reference dosi

  12. Secondary standard dosimetry laboratories: Development and trends

    International Nuclear Information System (INIS)

    This publication describes the work of the IAEA and the WHO in the establishment of a network of Secondary Standard Dosimetry Laboratories. Membership in the SSDL network has now risen to about 50 laboratories, of which 36 are in developing countries

  13. The United Kingdom's radiotherapy dosimetry audit network

    International Nuclear Information System (INIS)

    The first comprehensive national dosimetry intercomparison in the United Kingdom involving all UK radiotherapy centres was carried out in the late 1980s. Out of this a regular radiotherapy dosimetry audit network evolved in the early 1990s. The network is co-ordinated by the Institute of Physics and Engineering in Medicine and comprises eight co-operative regional groups. Audits are based on site visits using ionization chambers and epoxy resin water substitute phantoms. The basic audit methodology and phantom design follows that of the original national intercomparison exercise. However, most of the groups have evolved more complex methods, to extend the audit scope to include other parameters, other parts of the radiotherapy process and other treatment modalities. A number of the groups have developed phantoms to simulate various clinical treatment situations, enabling the sharing of phantoms and expertise between groups, but retaining a common base. Besides megavoltage external beam photon dosimetry, a number of the groups have also included the audit of kilovoltage X ray beams, electron beams and brachytherapy dosimetry. The National Physical Laboratory is involved in the network and carries out basic beam calibration audits to link the groups. The network is described and the methods and results are illustrated using the Scottish+ group as an example. (author)

  14. Computational Techniques of Electromagnetic Dosimetry for Humans

    Science.gov (United States)

    Hirata, Akimasa; Fujiwara, Osamu

    There has been increasing public concern about the adverse health effects of human exposure to electromagnetic fields. This paper reviews the rationale of international safety guidelines for human protection against electromagnetic fields. Then, this paper also presents computational techniques to conduct dosimetry in anatomically-based human body models. Computational examples and remaining problems are also described briefly.

  15. New dosimetry of atomic bomb radiations.

    Science.gov (United States)

    Fry, R J; Sinclair, W K

    1987-10-10

    The reassessment of the radiation dosimetry from the Hiroshima and Nagasaki atomic bombs is almost complete. Since atomic bomb survivors provide a major source of data for estimates of risk of cancer induction by radiation the impact of the new dosimetry on risk estimates and radiation protection standards is important. The changes include an increase of about 20% in the estimated yield of the Hiroshima bomb and a reduction in the estimated doses from neutrons in both cities. The estimated neutron dose for Hiroshima is about 10% of the previous estimate. The neutron doses are now so small that direct estimates of neutron relative biological effectiveness may be precluded or be much more difficult. There is little change in most of the gamma ray organ doses because various changes in the new estimates tend to cancel each other out. The new estimate of the attenuation of the free-in-air kerma by the walls of the homes is about twice that used in the previous dosimetry. But the transmission of gamma radiation to the deep organs such as bone marrow is significantly greater than earlier estimates. Probably future risk estimates for radiogenic cancer will be somewhat higher because of both the new dosimetry and the new cancer mortality data. New risk estimates should be available in 1988. PMID:2889042

  16. Personnel radiation dosimetry symposium: program and abstracts

    International Nuclear Information System (INIS)

    The purpose was to provide applied and research dosimetrists with sufficient information to evaluate the status and direction of their programs relative to the latest guidelines and techniques. A technical program was presented concerning experience, requirements, and advances in gamma, beta, and neutron personnel dosimetry

  17. Dosimetry and control of radiation processing

    International Nuclear Information System (INIS)

    Eight invited papers on the general theme of 'Dosimetry and Control of Radiation Processing', presented at a one day symposium held at the National Physical Laboratory, are collected together in this document. Seven of the papers are selected and indexed separately. (author)

  18. Optically stimulated luminescence techniques in retrospective dosimetry

    DEFF Research Database (Denmark)

    Bøtter-Jensen, L.; Murray, A.S.

    2001-01-01

    Optically stimulated luminescence signals from natural quartz and feldspar are now used routinely in dating geological and archaeological materials. More recently they have also been employed in accident dosimetry, i.e. the retrospective assessment of doses received as a result of a nuclear...

  19. Neutron dosimetry; Dosimetria de neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Fratin, Luciano

    1993-12-31

    A neutron irradiation facility was designed and built in order to establish a procedure for calibrating neutron monitors and dosemeters. A 185 GBq {sup 241} Am Be source of known is used as a reference source. The irradiation facility using this source in the air provides neutron dose rates between 9 nSv s{sup -1} and 0,5 {sup {mu}}Sv s{sup -1}. A calibrated 50 nSv s{sup -1} thermal neutron field is obtained by using a specially designed paraffin block in conjunction with the {sup 241} Am Be source. A Bonner multisphere spectrometer was calibrated, using a procedure based on three methods proposed by international standards. The unfold {sup 241} Am Be neutron spectrum was determined from the Bonner spheres data and resulted in a good agreement with expected values for fluence rate, dose rate and mean energy. A dosimetric system based on the electrochemical etching of CR-39 was developed for personal dosimetry. The dosemeter badge using a (n,{alpha}) converter, the etching chamber and high frequency power supply were designed and built specially for this project. The electrochemical etching (ECE) parameters used were: a 6N KOH solution, 59 deg C, 20 kV{sub pp} cm{sup -1}, 2,0 kHz, 3 hours of ECE for thermal and intermediate neutrons and 6 hours for fast neutrons. The calibration factors for thermal, intermediate and fast neutrons were determined for this personal dosemeter. The sensitivities determined for the developed dosimetric system were (1,46{+-} 0,09) 10{sup 4} tracks cm{sup -2} mSv{sup -1} for thermal neutrons, (9{+-}3) 10{sup 2} tracks cm{sup -2} mSV{sup -1} for intermediate neutrons and (26{+-}4) tracks cm{sup -2} mSv{sup -1} for fast neutrons. The lower and upper limits of detection were respectively 0,002 mSv and 0,6 mSv for thermal neutrons, 0,04 mSv and 8 mSv for intermediate neutrons and 1 mSv and 12 mSv for fast neutrons. In view of the 1990`s ICRP recommendations, it is possible to conclude that the personal dosemeter described in this work is

  20. Film dosimetry in conformal radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Danciu, C.; Proimos, B.S. [Patras Univ. (Greece). Dept. of Medical Physics

    1995-12-01

    Dosimetry, through a film sandwiched in a transverse cross-section of a solid phantom, is a method of choice in Conformal Radiotherapy because: (a) the blackness (density) of the film at each point offers a measure of the total dose received at that point, and (b) the film is easily calibrated by exposing a film strip in the same cross-section, through a stationary field. The film must therefore have the following properties: (a) it must be slow, in order not to be overexposed, even at a therapeutic dose of 200 cGy, and (b) the response of the film (density versus dose curve) must be independent of the photon energy spectrum. A few slow films were compared. It was found that the Kodak X-Omat V for therapy verification was the best choice. To investigate whether the film response was independent of the photon energy, response curves for six depths, starting from the depth of maximum dose to the depth of 25 cm, in solid phantom were derived. The vertical beam was perpendicular to the anterior surface of the phantom, which was at the distance of 100 cm from the source and the field was 15x15 cm at that distance. This procedure was repeated for photon beams emitted by a Cobalt-60 unit, two 6 MV and 15 MV Linear Accelerators, as well as a 45 MV Betatron. For each of those four different beams the film response was the same for all six depths. The results, as shown in the diagrams, are very satisfactory. The response curve under a geometry similar to that actually applied, when the film is irradiated in a transverse cross-section of the phantom, was derived. The horizontal beam was almost parallel (angle of 85) to the plane of the film. The same was repeated with the central ray parallel to the film (angle 90) and at a distance of 1.5 cm from the horizontal film. The field size was again 15x15 at the lateral entrance surface of the beam. The response curves remained the same, as when the beam was perpendicular to the films.

  1. 3-dimensional polymer gel dosimetry

    International Nuclear Information System (INIS)

    was observed. Polymer gel dosimetry system used in this study proved that it is reliable system for dose distribution measurement with error less than 5 % for doses higher than 3 Gy. (author)

  2. Dose modulated computed tomography automated dosimetry

    International Nuclear Information System (INIS)

    Full text: Computed Tomography (CT) scans contribute a significant portion of the effective radiation dose from medical procedures and generally large effective radiation doses per diagnostic examination. With the advent of Multislice CT, the potential for large radiation exposures increased. This combined with the appeal of the resultant isotropic imaging and the increasing number of applications for which CT could be utilised (including screening procedures) has further increased the need for vigilant monitoring of CT protocols and use with respect to radiation dose. The introduction of dose modulated Computed Tomography has proven an effective method for reducing patient dose and is now widely used by CT manufacturers. This involves lowering the mA when scanning through anatomical regions which do not require a large mA. Many CT investigations now utilise dose modulation. Some of these studies will include over 900 images for which the mA and occasionally other factors could vary. In order to utilise the existing software to perform CT dosimetry a program has been written to automatically extract scan parameters from CT dicom image files and apply the ImPACT CT Patient Dosimetry Calculator, for slices with differing factors. Matlab has been used to write and compile a program which sorts through a folder of dicom images and extracts the appropriate dicom header information. Some manufacturers store different series and reformatted images all within the same folder. The images of the CT study for which the dosimetry is to be performed must be stored within the one folder and must be in a dicom format. The program has been written to accommodate several manufacturers, which all contain different information in their dicom headers. The Matlab program groups the various study/image types, extracting the relevant dicom header information, which is written to an Excel worksheet. An Excel file uses this information to run the ImPACT CT Patient Dosimetry Calculator with

  3. Radiation dosimetry in radiotherapy with internal emitters

    Energy Technology Data Exchange (ETDEWEB)

    Stabin, Michael G. [Oak Ridge Inst. for Science and Education, TN (United States)

    1997-12-31

    Full text. Radiation dosimetry radionuclides are currently being labeled to various biological agents used in internal emitter radiotherapy. This talk will review the various technologies and types of radiolabel in current use, with focus on the characterization of the radiation dose to the various important tissues of the body. Methods for obtaining data, developing kinetic models, and calculating radiation doses will be reviewed. Monoclonal antibodies are currently being labeled with both alpha and beta emitting radionuclides in attempts to find effective agents against cancer. Several radionuclides are also being used as bone pain palliation agents. These agents must be studied in clinical trials to determine the biokinetics and radiation dosimetry prior to approval for general use. In such studies, it is important to ensure the collection of the appropriate kinds of data and to collect the data at appropriate time intervals. The uptake and retention of activity in all significant source organs and in excreta be measured periodically (with at least 2 data points phase of uptake or clearance). Then, correct dosimetry methods must be applied - the best available methods for characterizing the radionuclide kinetic and for estimating the dosimetry in the various organs of the body especially the marrow, should be used. Attempts are also under way to develop methods for estimating true patient-specific dosimetry. Cellular and animal studies are also. Valuable in evaluating the efficacy of the agents in shrinking or eliminating tumors; some results from such studies will also be discussed. The estimation of radiation doses to patients in therapy with internal emitters involves several complex phases of analysis. Careful attention to detail and the use of the best available methods are essential to the protection of the patient and a successful outcome

  4. Radiation processing dosimetry - past, present and future

    International Nuclear Information System (INIS)

    Since the two United Nations Conferences were held in Geneva in 1955 and 1958 on the Peaceful Uses of Atomic Energy and the concurrent foundation of the International Atomic Energy Agency in 1957, the IAEA has fostered high-dose dosimetry and its applications. This field is represented in industrial radiation processing, agricultural programmes, and therapeutic and preventative medicine. Such dosimetry is needed specifically for pest and quarantine control and in the processing of medical products, pharmaceuticals, blood products, foodstuffs, solid, liquid and gaseous wastes, and a variety of useful commodities, e.g. polymers, composites, natural rubber and elastomers, packaging, electronic, and automotive components, as well as in radiotherapy. Improvements and innovations of dosimetry materials and analytical systems and software continue to be important goals for these applications. Some of the recent advances in high-dose dosimetry include tetrazolium salts and substituted polydiacetylene as radiochromic media, on-line real-time as well as integrating semiconductor and diamond-detector monitors, quantitative label dosimeters, photofluorescent sensors for broad dose range applications, and improved and simplified parametric and computational codes for imaging and simulating 3D radiation dose distributions in model products. The use of certain solid-state devices, e.g. optical quality LiF, at low (down to 4K) and high (up to 500 K) temperatures, is of interest for materials testing. There have also been notable developments in experimental dose mapping procedures, e.g. 2D and 3D dose distribution analyses by flat-bed optical scanners and software applied to radiochromic and photofluorescent images. In addition, less expensive EPR spectrometers and new EPR dosimetry materials and high-resolution semiconductor diode arrays, charge injection devices, and photostimulated storage phosphors have been introduced. (author)

  5. Dynamic Average Consensus and Consensusability of General Linear Multiagent Systems with Random Packet Dropout

    Directory of Open Access Journals (Sweden)

    Wen-Min Zhou

    2013-01-01

    Full Text Available This paper is concerned with the consensus problem of general linear discrete-time multiagent systems (MASs with random packet dropout that happens during information exchange between agents. The packet dropout phenomenon is characterized as being a Bernoulli random process. A distributed consensus protocol with weighted graph is proposed to address the packet dropout phenomenon. Through introducing a new disagreement vector, a new framework is established to solve the consensus problem. Based on the control theory, the perturbation argument, and the matrix theory, the necessary and sufficient condition for MASs to reach mean-square consensus is derived in terms of stability of an array of low-dimensional matrices. Moreover, mean-square consensusable conditions with regard to network topology and agent dynamic structure are also provided. Finally, the effectiveness of the theoretical results is demonstrated through an illustrative example.

  6. Personal dosimetry service of VF, a.s. company

    International Nuclear Information System (INIS)

    The VF, a.s. Company will extend its services in the area of personal dosimetry at the end of 2008, which is fully in compliance with the requirements of the Atomic Act, section 9 paragraph (1) letter r) and Decree on Radiation Protection, section 59 paragraph (1) letter a). Optically stimulated luminescence was selected in VF .a.s. as the most advantageous and the most advanced technology for the integral personal dosimetry . Optically stimulated luminescence (OSL) has been using in dosimetry for more than ten years. Although it is relatively new technology , its indisputable advantages predetermine that technology has significantly benefited in personal dosimetry services within a short time all over the advanced world. The VF, a.s. personal dosimetry service is based on the licensed products of LANDAUER, the US company, which is the world leader in OSL dosimetry. Crystalline Al2O3:C was selected as the detection material. All equipment of personal dosimetry service is installed in the VF Centre of Technology in Cerna Hora. The personal dosimetry service is incorporated in the International LANDAUER Dosimetry Service Network, and in the European Union, it is directly linked to the LANDAUER European Headquarters with its office in Paris. As a part of the OSL technology licence, the VF personal dosimetry service was included in the inter-laboratory comparison programme of the LANDAUER syndicate. (author)

  7. An IAEA Survey of Dosimetry Audit Networks for Radiotherapy

    International Nuclear Information System (INIS)

    A Survey: In 2010, the IAEA undertook a task to investigate and review the coverage and operations of national and international dosimetry audit programmes for radiotherapy. The aim was to organize the global database describing the activities of dosimetry audit networks in radiotherapy. A dosimetry audit questionnaire has been designed at an IAEA consultants' meeting held in 2010 for organizations conducting various levels of dosimetry audits for radiotherapy. Using this questionnaire, a survey was conducted for the first time in 2010 and repeated in 2011. Request for information on different aspects of the dosimetry audit was included, such as the audit framework and resources, its coverage and scope, the dosimetry system used and the modes of audit operation, i.e. remotely and through on-site visits. The IAEA questionnaire was sent to over 80 organizations, members of the IAEA/WHO Network of Secondary Standards Dosimetry Laboratories (SSDLs) and other organizations known for having operated dosimetry audits for radiotherapy in their countries or internationally. Survey results and discussion: In response to the IAEA survey, 53 organizations in 45 countries confirmed that they operate dosimetry audit services for radiotherapy. Mostly, audits are conducted nationally, however there are five organizations offering audits abroad, with two of them operating in various parts of the world and three of them at the regional level, auditing radiotherapy centres in neighbouring countries. The distribution of dosimetry audit services in the world is given. (author)

  8. Lack of consensus in social systems

    Science.gov (United States)

    Benczik, I. J.; Benczik, S. Z.; Schmittmann, B.; Zia, R. K. P.

    2008-05-01

    We propose an exactly solvable model for the dynamics of voters in a two-party system. The opinion formation process is modeled on a random network of agents. The dynamical nature of interpersonal relations is also reflected in the model, as the connections in the network evolve with the dynamics of the voters. In the infinite time limit, an exact solution predicts the emergence of consensus, for arbitrary initial conditions. However, before consensus is reached, two different metastable states can persist for exponentially long times. One state reflects a perfect balancing of opinions, the other reflects a completely static situation. An estimate of the associated lifetimes suggests that lack of consensus is typical for large systems.

  9. Consensus in personality judgments at zero acquaintance.

    Science.gov (United States)

    Albright, L; Kenny, D A; Malloy, T E

    1988-09-01

    This research focused on the target effect on a perceiver's judgments of personality when the perceiver and the target are unacquainted. The perceiver was given no opportunity to interact with the target, a condition we refer to as zero acquaintance. We reasoned that in order to make personality judgments, perceivers would use the information available to them (physical appearance). Consensus in personality judgments would result, then, from shared stereotypes about particular physical appearance characteristics. Results from three separate studies with 259 subjects supported this hypothesis. On two of the five dimensions (extraversion and conscientiousness) on which subjects rated each other, a significant proportion of variance was due to the stimulus target. Consensus on judgments of extraversion appears to have been largely mediated by judgments of physical attractiveness. Across the three studies there was also evidence that the consensus in judgments on these two dimensions had some validity, in that they correlated with self-judgments on those two dimensions. PMID:3171912

  10. Fastest Distributed Consensus on Petal Networks

    CERN Document Server

    Jafarizadeh, Saber

    2010-01-01

    Providing an analytical solution for the problem of finding Fastest Distributed Consensus (FDC) is one of the challenging problems in the field of sensor networks. Here in this work we present analytical solution for the problem of fastest distributed consensus averaging algorithm by means of stratification and semi-definite programming, for two particular types of Petal networks, namely symmetric and Complete Cored Symmetric (CCS) Petal networks. Our method in this paper is based on convexity of fastest distributed consensus averaging problem, and inductive comparing of the characteristic polynomials initiated by slackness conditions in order to find the optimal weights. Also certain types of leaves are introduced along with their optimal weights which are not achievable by the method used in this work if these leaves are considered individually.

  11. Review of translocations detected by fish for retrospective biological dosimetry applications

    International Nuclear Information System (INIS)

    Several European laboratories have combined their research efforts to arrive at a consensus view on using fluorescence in situ hybridisation (FISH) for retrospective dosimetry. The aim of this review is to report these views and to highlight some areas where further work is needed. Translocations in the stable cells should be measured only in the cells that contain the full complement of the painted material. Two-way and one-way translocations should be combined with equal weight. The control level of translocations has a strong dependence on age, which has now been measured and the system has been calibrated. In conclusion, the technique works and a lifetime dose to the bone marrow from low-linear energy transfer radiation of 0.5 Gy above normal background levels can be measured for any individual. The main application is considered to provide an independent verification of lifetime doses to individuals who might form a part of an epidemiological study. (authors)

  12. Consensus dynamics on random rectangular graphs

    Science.gov (United States)

    Estrada, Ernesto; Sheerin, Matthew

    2016-06-01

    A random rectangular graph (RRG) is a generalization of the random geometric graph (RGG) in which the nodes are embedded into a rectangle with side lengths a and b = 1 / a, instead of on a unit square [ 0 , 1 ] 2. Two nodes are then connected if and only if they are separated at a Euclidean distance smaller than or equal to a certain threshold radius r. When a = 1 the RRG is identical to the RGG. Here we apply the consensus dynamics model to the RRG. Our main result is a lower bound for the time of consensus, i.e., the time at which the network reaches a global consensus state. To prove this result we need first to find an upper bound for the algebraic connectivity of the RRG, i.e., the second smallest eigenvalue of the combinatorial Laplacian of the graph. This bound is based on a tight lower bound found for the graph diameter. Our results prove that as the rectangle in which the nodes are embedded becomes more elongated, the RRG becomes a 'large-world', i.e., the diameter grows to infinity, and a poorly-connected graph, i.e., the algebraic connectivity decays to zero. The main consequence of these findings is the proof that the time of consensus in RRGs grows to infinity as the rectangle becomes more elongated. In closing, consensus dynamics in RRGs strongly depend on the geometric characteristics of the embedding space, and reaching the consensus state becomes more difficult as the rectangle is more elongated.

  13. 12''th International Conference on Solid State Dosimetry Casa del Cordon. Conference Center (Caja de Burgos), July 5''th-10''th, 1998, Burgos Spain: Programme and Abstracts

    International Nuclear Information System (INIS)

    The 12 International Conference on Solid State Dosimetry celebrate in Burgos (Spain) during July on 1998. 1.- Basic Physical Processes 2.- Materials characteristics 3.- Instrumentation 4.- Personal Dosimetry 5.- Clinical Dosimetry 6.- Environmental Dosimetry 7.- Dating retrospective dosimetry 8.- Miscellaneous

  14. Overlapping community detection using weighted consensus clustering

    Indian Academy of Sciences (India)

    LINTAO YANG; ZETAI YU; JING QIAN; SHOUYIN LIU

    2016-10-01

    Many overlapping community detection algorithms have been proposed. Most of them are unstable and behave non-deterministically. In this paper, we use weighted consensus clustering for combining multiple base covers obtained by classic non-deterministic algorithms to improve the quality of the results. We first evaluate a reliability measure for each community in all base covers and assign a proportional weight to each one. Then we redefine the consensus matrix that takes into account not only the common membership of nodes, but also the reliability of the communities. Experimental results on both artificial and real-world networks show that our algorithm can find overlapping communities accurately.

  15. Dosimetry for members of the extended Techa River cohort

    Energy Technology Data Exchange (ETDEWEB)

    Anspaugh, L R.; Degteva, M. O.; Vorobiova, M I.; Mokrov, Y; Napier, Bruce A.

    2006-10-01

    The undersigned and colleagues are creators and a critic of the Techa River Dosimetry System-2000 (TRDS-2000), which was the subject of a recent article by Balonov et al. This article presented a consensus on a review of the TRDS-2000 achieved following a workshop in December 2003. The TRDS-2000 was used to derive risk coefficients for members of an unselected general population exposed to moderate doses of radiation at low dose rates on the Techa River in the 1950s. Because it is now more than two years since the workshop, a significant number of events have transpired, and the purpose of this letter is to inform readers of current developments. As noted in Balonov et al., much of the concern about the dosimetric and epidemiologic investigation of the Extended Techa River Cohort was heightened by a preliminary derivation of risk estimates that were higher than those derived from study of the survivors of the atomic bombings in Japan, but not significantly different. Similar results showing risks for leukemia and solid cancers about 50% higher than those in the Japanese survivors have now been published. These unexpected results have raised the issue of the validity of the doses being calculated with the TRDS-2000. Much of the honest differences of opinion among the undersigned about the TRDS-2000 is concerned with the accuracy and precision of the releases to the Techa River during the 1949-1951 period. Balonov et al. recommended many steps to investigate further information available on the releases, and to take other steps to resolve differences in opinion. As noted by Balonov et al., one of the more promising was a proposed study (with funding requested from the International Science and Technology Center) for the undersigned to work together on the ?source-term problem? along with additional Russian experts from the Institute of Plant and Animal Ecology, Ekaterinburg, and the Zababakhin Institute of Technical Physics, Snezhinsk. We are pleased that the study

  16. Dosimetry for members of the extended Techa River cohort

    International Nuclear Information System (INIS)

    The undersigned and colleagues are creators and a critic of the Techa River Dosimetry System-2000 (TRDS-2000), which was the subject of a recent article by Balonov et al. This article presented a consensus on a review of the TRDS-2000 achieved following a workshop in December 2003. The TRDS-2000 was used to derive risk coefficients for members of an unselected general population exposed to moderate doses of radiation at low dose rates on the Techa River in the 1950s. Because it is now more than two years since the workshop, a significant number of events have transpired, and the purpose of this letter is to inform readers of current developments. As noted in Balonov et al., much of the concern about the dosimetric and epidemiologic investigation of the Extended Techa River Cohort was heightened by a preliminary derivation of risk estimates that were higher than those derived from study of the survivors of the atomic bombings in Japan, but not significantly different. Similar results showing risks for leukemia and solid cancers about 50% higher than those in the Japanese survivors have now been published. These unexpected results have raised the issue of the validity of the doses being calculated with the TRDS-2000. Much of the honest differences of opinion among the undersigned about the TRDS-2000 is concerned with the accuracy and precision of the releases to the Techa River during the 1949-1951 period. Balonov et al. recommended many steps to investigate further information available on the releases, and to take other steps to resolve differences in opinion. As noted by Balonov et al., one of the more promising was a proposed study (with funding requested from the International Science and Technology Center) for the undersigned to work together on the ?source-term problem? along with additional Russian experts from the Institute of Plant and Animal Ecology, Ekaterinburg, and the Zababakhin Institute of Technical Physics, Snezhinsk. We are pleased that the study

  17. Experiences with alanine dosimetry in afterloading brachytherapy

    International Nuclear Information System (INIS)

    At the present, the most commonly used dosimetry for radiotherapy applications are ionisation chambers and thermoluminescent dosimeters (TLD). However, there are some undesirable characteristics of these dosimetry systems, such as large detection volume (ionisation chamber) as well as fading of the radiation induced signal with time and destructive readout (TLG). The present study is an investigation into the use of the alanine/ESR dosimetry in fractionated afterloading brachytherapy during the whole radiotherapy course. There are some qualities which make alanine dosimetry attractive. These are the linear energy response, low fading under standard conditions, and the nondestructive readout. Thus the alanine dosimetry makes possible cumulative dose measurements during the radiotherapy course and an archival storage. By ionizing radiation (gamma, e, n, p, charged particles) free radicals (unpaired electrons) are produced in the amino acid alanine. The continuous wave electron spin resonance (ESR) spectroscopy is used to determine the number of free radicals, which is proportional to the absorbed dose and the alanine content of the dosimeter. The ESR measurements were made at room temperature using a Bruker EPR analyzer EMS-104. The dosimeters used in the test are alanine pellets (23.72 mg weight, 4.9 mm diameter, 1 mm height) as well as flexible alanine film dosimeters (thickness about 500 μm). The dosimeters consist of a blend of L-alpha-alanine and a binder. The alanine content of the pellets and the film dosimeters is about 88 % and 50 % by weight, respectively. The dosimeters for the calculation of the dose-effect-relationship were irradiated at the Physical-Technical Bundesanstalt in Braunschweig by a standard 60Co source. The maximum deviation from the calculated linear function is about 0.12 Gy in the dose range up to 80 Gy. The goal of medical applications was the superficial dose measurement in afterloading brachytherapy during the radiotherapy course in

  18. Thermoluminescence in medical dosimetry; Termoluminiscencia en dosimetria medica

    Energy Technology Data Exchange (ETDEWEB)

    Rivera, T., E-mail: trivera@ipn.mx [IPN, Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada, Av. Legaria 694, Col. Irrigacion, 11500 Mexico D. F. (Mexico)

    2011-10-15

    The dosimetry by thermoluminescence (Tl) is applied in the entire world for the dosimetry of ionizing radiations specially to personal and medical dosimetry. This dosimetry method has been very interesting for measures in vivo because the Tl dosimeters have the advantage of being very sensitive in a very small volume and they are also equivalent to tissue and they do not need additional accessories (for example, cable, electrometer, etc.) The main characteristics of the diverse Tl materials to be used in the radiation measures and practical applications are: the Tl curve, the share homogeneity, the signal stability after the irradiation, precision and exactitude, the response in function with the dose and the energy influence. In this work a brief summary of the advances of the radiations dosimetry is presented by means of the thermally stimulated luminescence and its application to the dosimetry in radiotherapy. (Author)

  19. Acute Renal Failure and the Critically Ill Surgical Patient

    OpenAIRE

    Sykes, Eliot; Cosgrove, Joseph F

    2007-01-01

    Acute renal failure can occur following major surgery. Predisposing factors include massive haemorrhage, sepsis, diabetes, hypertension, cardiac disease, peripheral vascular disease, chronic renal impairment and age. Understanding epidemiology, aetiology and pathophysiology can aid effective diagnosis and management. A consensus definition for acute renal failure has recently been developed. It relates to deteriorating urine output, serum creatinine and glomerular filtration rate. In the surg...

  20. Small Field Dosimetry Using Optical-Fiber Radioluminescence and Radpos Dosimetry Systems

    DEFF Research Database (Denmark)

    Ploquin, N.; Kertzscher Schwencke, Gustavo Adolfo Vladimir; Vandervoort, E.;

    2012-01-01

    to the small dimensions of the Al2O3 crystal, the system may have applications in small field dosimetry. The second system is the RADPOS system (Med Phys, 36, 167279, 2009), a novel 4D dosimetry system available from BEST Medical Canada. RADPOS probe consists of 2 sensors: a small antenna......Purpose/Objective: We have investigated the use of two new dosimetry systems for small field dosimetry. The first system is based on Al2O3:C radioluminescence (RL) (Radiat Meas, 46 (10), 109098, 2011). The main part of the RL dosimetry system is a small (2x0.5x0.5 mm3) Al2O3:C crystal (Landauer...... as an electromagnetic positioning sensor and a μMOSFET for dose measurement. Materials and Methods: Relative output factors (ROF) for Cyberknife cones ranging from 5 to 60 mm were measured using RL and RADPOS systems. For comparison, measurements were also carried out using a mobileMOSFET system (BEST Medical Canada...

  1. Personal dosimetry for external radiation exposure in Europe

    International Nuclear Information System (INIS)

    This article summarizes a report on harmonisation and dosimetric quality assurance in individual monitoring for external radiation, published by the European Radiation Dosimetry Group (EURADOS). The report comprises three parts: (1) procedures and regulations in countries of the European Union and Switzerland with respect to personal dosimetry; (2) a catalogue with descriptions of dosimetry systems in the fore-mentioned countries; and (3) performance testing of dosimetric services in EU Member States and Switzerland. 17 refs

  2. Teacher Effectiveness in Physical Education--Consensus?

    Science.gov (United States)

    Rink, Judith

    2014-01-01

    This article synthesizes the series of manuscripts on teacher effectiveness in physical education recently published by the "Research Quarterly for Exercise and Sport" and highlights both the consensus and points of disagreement. Although there is much agreement as to the mission to develop a physically active lifestyle, there is a great…

  3. Adaptive bipartite consensus on coopetition networks

    Science.gov (United States)

    Hu, Jiangping; Zhu, Hong

    2015-07-01

    In this paper, a bipartite consensus tracking problem is considered for a group of autonomous agents on a coopetition network, on which the agents interact cooperatively and competitively simultaneously. The coopetition network involves positive and negative edges and is conveniently modeled by a signed graph. Additionally, the dynamics of all the agents are subjected to unknown disturbances, which are represented by linearly parameterized models. An adaptive estimation scheme is designed for each agent by virtue of the relative position measurements and the relative velocity measurements from its neighbors. Then a consensus tracking law is proposed for a new distributed system, which uses the relative measurements as the new state variables. The convergence of the consensus tracking error and the parameter estimation are analyzed even when the coopetition network is time-varying and no more global information about the bounds of the unknown disturbances is available to all the agents. Finally, some simulation results are provided to demonstrate the formation of the bipartite consensus on the coopetition network.

  4. Consumer and professional standards: working towards consensus

    OpenAIRE

    C. Williamson

    2000-01-01

    Standards of treatment and care should be acceptable to healthcare consumers as well as to healthcare professionals. A simple categorisation of standards according to their acceptability to consumers is outlined. Professional/consumer groups which review and set standards are discussed, with emphasis on the principles of partnership. Working together towards consensus can be difficult but is now an important way forward.

  5. Introduction: experts and consensus in social science

    NARCIS (Netherlands)

    M. Boumans; C. Martini

    2014-01-01

    The ideals of science as objectivity and consensus are - unsurprisingly - not so easy to attain in scientific practice. Science is ultimately a product of individual scientists with their own personal backgrounds and experiences, and there is no unique methodology to de-personalize and objectify kno

  6. Consensus among Economics Teachers from Transition Economies

    Science.gov (United States)

    Leet, Don R.; Lang, Nancy A.

    2010-01-01

    The authors analyze the economic opinions of teachers and economists from the former Soviet Union who participated in economic education programs sponsored by the U.S. Department of Education under the auspices of the National Council on Economic Education from 1995-2001. They sought to determine the level of consensus on economic topics among the…

  7. Consensus over peri-implantaire infecties

    NARCIS (Netherlands)

    van Winkelhoff, A J

    2010-01-01

    In 2008, in a workshop of the European Federation on Periodontology, a consensus was reached concerning oral peri-implant infections on the basis of the state of the art in the relevant sciences. Important conclusions were that peri-implant mucositis occurs in 80% of subjects with oral implants, and

  8. Discontinuities and hysteresis in quantized average consensus

    NARCIS (Netherlands)

    Ceragioli, Francesca; Persis, Claudio De; Frasca, Paolo

    2011-01-01

    We consider continuous-time average consensus dynamics in which the agents’ states are communicated through uniform quantizers. Solutions to the resulting system are defined in the Krasowskii sense and are proven to converge to conditions of ‘‘practical consensus’’. To cope with undesired chattering

  9. Health Promoting Schools: Consensus, Strategies, and Potential

    Science.gov (United States)

    Macnab, Andrew J.; Gagnon, Faith A.; Stewart, Donald

    2014-01-01

    Purpose: The purpose of this paper is to summarize a consensus statement generated on the current challenges, strategies, and potential of health promoting schools (HPS) at a 2011 colloquium at the Stellenbosch Institute for Advanced Study where 40 people from five continents came together to share their global and regional experience surrounding…

  10. 3rd BRAZILIAN CONSENSUS ON Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    Luiz Gonzaga Coelho

    2013-04-01

    Full Text Available Significant progress has been obtained since the Second Brazilian Consensus Conference on Helicobacter pylori Infection held in 2004, in São Paulo, SP, Brazil, and justify a third meeting to establish updated guidelines on the current management of H. pylori infection. The Third Brazilian Consensus Conference on H pylori Infection was organized by the Brazilian Nucleus for the Study of Helicobacter, a Department of the Brazilian Federation of Gastroenterology and took place on April 12-15, 2011, in Bento Gonçalves, RS, Brazil. Thirty-one delegates coming from the five Brazilian regions and one international guest, including gastroenterologists, pathologists, epidemiologists, and pediatricians undertook the meeting. The participants were allocated in one of the five main topics of the meeting: H pylori, functional dyspepsia and diagnosis; H pylori and gastric cancer; H pylori and other associated disorders; H pylori treatment and retreatment; and, epidemiology of H pylori infection in Brazil. The results of each subgroup were submitted to a final consensus voting to all participants. Relevant data were presented, and the quality of evidence, strength of recommendation, and level of consensus were graded. Seventy per cent and more votes were considered as acceptance for the final statement. This article presents the main recommendations and conclusions to guide Brazilian doctors involved in the management of H pylori infection.

  11. International Consensus for ultrasound lesions in gout

    DEFF Research Database (Denmark)

    Gutierrez, Marwin; Schmidt, Wolfgang A; Thiele, Ralf G;

    2015-01-01

    OBJECTIVE: To produce consensus-based definitions of the US elementary lesions in gout and to test their reliability in a web-based exercise. METHODS: The process consisted of two steps. In the first step a written Delphi questionnaire was developed from a systematic literature review and expert ...

  12. Technical basis document for internal dosimetry

    CERN Document Server

    Hickman, D P

    1991-01-01

    This document provides the technical basis for the Chem-Nuclear Geotech (Geotech) internal dosimetry program. Geotech policy describes the intentions of the company in complying with radiation protection standards and the as low as reasonably achievable (ALARA) program. It uses this policy and applicable protection standards to derive acceptable methods and levels of bioassay to assure compliance. The models and computational methods used are described in detail within this document. FR-om these models, dose- conversion factors and derived limits are computed. These computations are then verified using existing documentation and verification information or by demonstration of the calculations used to obtain the dose-conversion factors and derived limits. Recommendations for methods of optimizing the internal dosimetry program to provide effective monitoring and dose assessment for workers are provided in the last section of this document. This document is intended to be used in establishing an accredited dosi...

  13. Eleventh DOE workshop on personnel neutron dosimetry

    International Nuclear Information System (INIS)

    Since its formation, the Office of Health (EH-40) has stressed the importance of the exchange of information related to and improvements in neutron dosimetry. This Workshop was the eleventh in the series sponsored by the Department of Energy (DOE). It provided a forum for operational personnel at DOE facilities to discuss current issues related to neutron dosimetry and for leading investigators in the field to discuss promising approaches for future research. A total of 26 papers were presented including the keynote address by Dr. Warren K. Sinclair, who spoke on, ''The 1990 Recommendations of the ICRP and their Biological Background.'' The first several papers discussed difficulties in measuring neutrons of different energies and ways of compensating or deriving correction factors at individual facilities. Presentations were also given by the US Navy and Air Force. Current research in neutron dosimeter development was the subject of the largest number of papers. These included a number on the development of neutron spectrometers

  14. Mathematical operations in cytogenetic dosimetry: Dosgen

    International Nuclear Information System (INIS)

    Handling of formulas and mathematical procedures for fitting and using of dose-response relationships in cytogenetic dosimetry is often difficulted by the absence of collaborators specialized in mathematics and computation. DOSGEN program contains the main mathematical operations which are used in cytogenetic dosimetry. It is able to run in IBM compatible Pc's by non-specialized personnel.The program possibilities are: Poisson distribution fitting test for the number of aberration per cell, dose assessment for whole body irradiation, dose assessment for partial irradiation and determination of irradiated fraction. The program allows on screen visualization and printing of results. DOSGEN has been developed in turbo pascal and is 33Kb of size. (authors). 4 refs

  15. Trigeminal neuralgia treatment dosimetry of the Cyberknife

    International Nuclear Information System (INIS)

    There are 2 Cyberknife units at Stanford University. The robot of 1 Cyberknife is positioned on the patient's right, whereas the second is on the patient's left. The present study examines whether there is any difference in dosimetry when we are treating patients with trigeminal neuralgia when the target is on the right side or the left side of the patient. In addition, we also study whether Monte Carlo dose calculation has any effect on the dosimetry. We concluded that the clinical and dosimetric outcomes of CyberKnife treatment for trigeminal neuralgia are independent of the robot position. Monte Carlo calculation algorithm may be useful in deriving the dose necessary for trigeminal neuralgia treatments.

  16. Trigeminal neuralgia treatment dosimetry of the Cyberknife

    Energy Technology Data Exchange (ETDEWEB)

    Ho, Anthony [Department of Radiation Oncology, Stanford University, Stanford, CA (United States); Lo, Anthony T., E-mail: tonyho22003@yahoo.com [Department of Radiation Oncology, Stanford University, Stanford, CA (United States); Dieterich, Sonja; Soltys, Scott G.; Gibbs, Iris C. [Department of Radiation Oncology, Stanford University, Stanford, CA (United States); Chang, Steve G.; Adler, John R. [Department of Neurosurgery, Stanford University, Stanford, CA (United States)

    2012-04-01

    There are 2 Cyberknife units at Stanford University. The robot of 1 Cyberknife is positioned on the patient's right, whereas the second is on the patient's left. The present study examines whether there is any difference in dosimetry when we are treating patients with trigeminal neuralgia when the target is on the right side or the left side of the patient. In addition, we also study whether Monte Carlo dose calculation has any effect on the dosimetry. We concluded that the clinical and dosimetric outcomes of CyberKnife treatment for trigeminal neuralgia are independent of the robot position. Monte Carlo calculation algorithm may be useful in deriving the dose necessary for trigeminal neuralgia treatments.

  17. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2005-02-25

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database.

  18. Radio-analysis. Applications: biological dosimetry; Radioanalyse. Applications: dosage biologique

    Energy Technology Data Exchange (ETDEWEB)

    Bourrel, F. [CEA Saclay, INSTN, Institut National des Sciences et Techniques Nucleaires, 91 - Gif-sur-Yvette (France); Courriere, Ph. [UFR de Pharmacie, 31 - Toulouse (France)

    2003-06-01

    Radioisotopes have revolutionized the medical biology. Radio-immunology remains the reference measurement of the infinitely small in biology. Constant efforts have been performed to improve the simpleness, detectability and fastness of the method thanks to an increasing automation. This paper presents: 1 - the advantages of compounds labelling and the isotopic dilution; 2 - the antigen-antibody system: properties, determination of the affinity constant using the Scatchard method; 3 - radio-immunologic dosimetry: competitive dosimetry (radioimmunoassay), calibration curve and mathematical data processing, application to the free thyroxine dosimetry, immunoradiometric dosimetry (immunoradiometric assay), evaluation of the analytical efficiency of a radioimmunoassay; 4 - detection of the radioactive signal (solid and liquid scintillation). (J.S.)

  19. Utilization of photodiodes for ionizing radiation dosimetry

    International Nuclear Information System (INIS)

    The behaviour of silicon photodiodes as detector, for gama and x-ray dosimetry is discussed. Measurements were realized with photodiodes operating in the photovoltaic mode, the current produzed was detected in the eletrometer constructed in the DEN/UFPE. The results obtained showed that the photodiode response is linear with the dose and that variation of 40 degrees in the incidence angule of the radiation caused a variation of 5% in the dose determination. (author)

  20. Current status of internal dosimetry in Lithuania

    Energy Technology Data Exchange (ETDEWEB)

    Griciene, B.; Ladygiene, R.; Morkunas, G.; Pilkyte, L

    2003-07-01

    After Lithuania regained independence, the legal basis for existing radiation protection was modified radically according to the IAEA, ICRP recommendations and the requirements of legislation of the European Community. The legal basis for internal dosimetry and a functioning system of assessment of exposure to intake of radionuclides have been created in the Radiation Protection Centre (regulatory authority in radiation protection). Direct and indirect measurements of concentrations of radionuclides are used for the assessment of internal doses of workers and the public. (author)

  1. Current status of internal dosimetry in Lithuania

    International Nuclear Information System (INIS)

    After Lithuania regained independence, the legal basis for existing radiation protection was modified radically according to the IAEA, ICRP recommendations and the requirements of legislation of the European Community. The legal basis for internal dosimetry and a functioning system of assessment of exposure to intake of radionuclides have been created in the Radiation Protection Centre (regulatory authority in radiation protection). Direct and indirect measurements of concentrations of radionuclides are used for the assessment of internal doses of workers and the public. (author)

  2. a Generalized Program for Internal Radionuclide Dosimetry

    Science.gov (United States)

    Johnson, Timothy Karl

    The development of monoclonal antibodies specific for tumor surface antigens promises a highly specific carrier medium for delivering a tumorcidal radiation dose. Dosimetry calculations of monoclonal antibodies are made difficult, however, precisely because the focus of radioactivity is targeted for a nonstandard volume in a nonstandard geometry. This precludes straightforward application of the formalism developed for internal radionuclide dosimetry by the Medical Internal Radiation Dose Committee. A software program was written to account for the perturbations introduced by the inclusion of a tumor mass as an additional source of, and target for, radiation. The program allows the interactive development of a mathematical model to account for observed biodistribution data. The model describes the time dependence of radioactivity in each organ system that retains radiolabeled antibody, including tumor. Integration of these "time-activity" curves yield cumulative activity for each organ system identified as a 'source' of radioactivity. A Monte Carlo simulation of photon transport is then executed for each source organ to obtain the fraction of radiation energy absorbed by various 'target' organs. When combined with the cumulative activity, this absorbed fraction allows an estimate of dose to be made for each target organ. The program has been validated against ten analytic models designed to span a range of common input data types. Additionally, a performance benchmark has been defined to assess the practicality of implementing the program on different computing hardware platforms. Sources of error in the computation are elaborated on, and future directions and improvements discussed. The software presents an integrated modeling/dosimetry environment particularly suited for performing Monoclonal Antibody dosimetry. It offers a viable methodology for performing prospective treatment planning, based on extrapolation of tracer kinetic data to therapeutic levels.

  3. Dosimetry intercomparisons between fast neutron radiotherapy facilities

    International Nuclear Information System (INIS)

    Neutron dosimetry intercomparisons have been made between M.D. Anderson Hospital and Tumor Institute, Naval Research Laboratory, University of Washington Hospital, and Hammersmith Hospital. The parameters that are measured during these visits are: tissue kerma in air, tissue dose at depth of dose maximum, depth dose, beam profiles, neutron/gamma ratios and photon calibrations of ionization chambers. A preliminary report of these intercomparisons will be given including a comparison of the calculation and statement of tumor doses for each institution

  4. Applications of alanine-based dosimetry

    International Nuclear Information System (INIS)

    Alanine-based radiation dosimetry and related dosimeters developed at the Istituto Superiore di Sanita, Rome, Italy, and capable of providing high accuracy absorbed dose determination by ESR are presented. Overall uncertainty is shown to be +-3.9% in the 10 Gy to 3 kGy range. Possible applications to radiotherapy and industry are discussed. Percentage depth dose values and dose profiles measured with alanine dosimeters in phantom are presented. (author)

  5. Calliope. A pedagogic tool for internal dosimetry

    International Nuclear Information System (INIS)

    The Calliope CD-Rom brings together all principal data published in the documents of the international commission of radiation protection (ICRP) since 1990. Calliope is a support devoted to the training of professionals and future actors of radioprotection (doctors, biologists, radiation protection services, teachers etc..). It provides some useful help for the enforcement and the respect of new dosimetry standards as defined in the European directive 96/29. (J.S.)

  6. Thermocurrent dosimetry with high purity aluminum oxide

    Energy Technology Data Exchange (ETDEWEB)

    Fullerton, G.D.; Cameron, J.R.; Moran, P.R.

    1976-01-01

    The application of thermocurrent (TC) to ionizing radiation dosimetry was studied. It was shown that TC in alumina (Al/sub 2/O/sub 3/) has properties that are suited to personnel dosimetry and environmental monitoring. TC dosimeters were made from thin disks of alumina. Aluminum electrodes were evaporated on each side: on one face a high voltage electrode and on the opposite face a measuring electrode encircled by a guard ring. Exposure to ionizing radiation resulted in stored electrons and holes in metastable trapping sites. The signal was read-out by heating the dosimeter with a voltage source and picnometer connected in series between the opposite electrodes. The thermally remobilized charge caused a transient TC. The thermogram, TC versus time or temperature, is similar to a TL glow curve. Either the peak current or the integrated current is a measure of absorbed dose. Six grades of alumina were studied from a total of four commercial suppliers. All six materials displayed radiation induced TC signals. Sapphire of uv-grade quality from the Adolf Meller Co. (AM) had the best dosimetry properties of those investigated. Sources of interference were studied. Thermal fading, residual signal and radiation damage do not limit TC dosimetry. Ultraviolet light can induce a TC response but it is readily excluded with uv-opaque cladding. Improper surface preparation prior to electrode evaporation was shown to cause interference. A spurious TC signal resulted from polarization of surface contaminants. Spurious TC was reduced by improved cleaning prior to electrode application. Polished surfaces resulted in blocking electrodes and caused a sensitivity shift due to radiation induced thermally activated polarization. This was not observed with rough cut surfaces.

  7. Radiotherapy Based On α Emitting Radionuclides: Geant4 For Dosimetry And Micro-/Nano-Dosimetry

    International Nuclear Information System (INIS)

    Possible physics approaches to evaluate the efficacy of TAT are dosimetry, microdosimetry and nanodosimetry. Dosimetry is adequate when mean absorbed dose to a macroscopic target volume is important to understand the biological effect of radiation. General purpose Monte Carlo (MC) codes, based on condensed history approach, are a very useful, cost effective tool to solve dosimetric problems. The condensed history approach is based on the use of multiple scattering theories to calculate the energy losses and angular changes in the direction of the particle. The short α particle range and high LET make the microdosimetric approach more suitable than dosimetry to study TAT from first physics principles, as this approach takes into account the stochastic nature of energy deposition at cellular level

  8. Technical basis document for internal dosimetry

    International Nuclear Information System (INIS)

    This document provides the technical basis for the Chem-Nuclear Geotech (Geotech) internal dosimetry program. Geotech policy describes the intentions of the company in complying with radiation protection standards and the as low as reasonably achievable (ALARA) program. It uses this policy and applicable protection standards to derive acceptable methods and levels of bioassay to assure compliance. The models and computational methods used are described in detail within this document. FR-om these models, dose- conversion factors and derived limits are computed. These computations are then verified using existing documentation and verification information or by demonstration of the calculations used to obtain the dose-conversion factors and derived limits. Recommendations for methods of optimizing the internal dosimetry program to provide effective monitoring and dose assessment for workers are provided in the last section of this document. This document is intended to be used in establishing an accredited dosimetry program in accordance with expected Department of Energy Laboratory Accreditation Program (DOELAP) requirements for the selected radionuclides provided in this document, including uranium mill tailing mixtures. Additions and modifications to this document and procedures derived FR-om this document are expected in the future according to changes in standards and changes in programmatic mission

  9. EPR dosimetry with tooth enamel: A review.

    Science.gov (United States)

    Fattibene, Paola; Callens, Freddy

    2010-11-01

    When tooth enamel is exposed to ionizing radiation, radicals are formed, which can be detected using electron paramagnetic resonance (EPR) techniques. EPR dosimetry using tooth enamel is based on the (presumed) correlation between the intensity or amplitude of some of the radiation-induced signals with the dose absorbed in the enamel. In the present paper a critical review is given of this widely applied dosimetric method. The first part of the paper is fairly fundamental and deals with the main properties of tooth enamel and some of its model systems (e.g., synthetic apatites). Considerable attention is also paid to the numerous radiation-induced and native EPR signals and the radicals responsible for them. The relevant methods for EPR detection, identification and spectrum analyzing are reviewed from a general point of view. Finally, the needs for solid-state modelling and studies of the linearity of the dose response are investigated. The second part is devoted to the practical implementation of EPR dosimetry using enamel. It concerns specific problems of preparation of samples, their irradiation and spectrum acquisition. It also describes how the dosimetric signal intensity and dose can be retrieved from the EPR spectra. Special attention is paid to the energy dependence of the EPR response and to sources of uncertainties. Results of and problems encountered in international intercomparisons and epidemiological studies are also dealt with. In the final section the future of EPR dosimetry with tooth enamel is analyzed.

  10. EPR dosimetry with tooth enamel: A review

    Energy Technology Data Exchange (ETDEWEB)

    Fattibene, Paola, E-mail: paola.fattibene@iss.i [Istituto Superiore di Sanita, Department of Technology and Health, Viale Regina Elena 299, I-00161 Rome (Italy); Callens, Freddy, E-mail: freddy.callens@ugent.b [Ghent University, Department of Solid State Sciences, Krijgslaan 281-S1, B-9000 Gent (Belgium)

    2010-11-15

    When tooth enamel is exposed to ionizing radiation, radicals are formed, which can be detected using electron paramagnetic resonance (EPR) techniques. EPR dosimetry using tooth enamel is based on the (presumed) correlation between the intensity or amplitude of some of the radiation-induced signals with the dose absorbed in the enamel. In the present paper a critical review is given of this widely applied dosimetric method. The first part of the paper is fairly fundamental and deals with the main properties of tooth enamel and some of its model systems (e.g., synthetic apatites). Considerable attention is also paid to the numerous radiation-induced and native EPR signals and the radicals responsible for them. The relevant methods for EPR detection, identification and spectrum analyzing are reviewed from a general point of view. Finally, the needs for solid-state modelling and studies of the linearity of the dose response are investigated. The second part is devoted to the practical implementation of EPR dosimetry using enamel. It concerns specific problems of preparation of samples, their irradiation and spectrum acquisition. It also describes how the dosimetric signal intensity and dose can be retrieved from the EPR spectra. Special attention is paid to the energy dependence of the EPR response and to sources of uncertainties. Results of and problems encountered in international intercomparisons and epidemiological studies are also dealt with. In the final section the future of EPR dosimetry with tooth enamel is analyzed.

  11. Electron paramagnetic resonance dosimetry using synthetic hydroxyapatite

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Kwon; Kim, Hwi Young; Ye, Sung Joon [Seoul National University, Seoul (Korea, Republic of); Hirata, Hiroshi [Hokkaido University, Sapporo (Japan); Park, Jong Min [Seoul National University Hospital, Seoul (Korea, Republic of)

    2014-11-15

    The victims exposed doses under 3.5-4.0 Gy have chance to survive if treated urgently. To determine the priority of treatment among a large number of victims, the triage – distinguishing patients who need an urgent treatment from who may not be urgent – is necessary based on radiation biodosimetry. A current gold standard for radiation biodosimetry is the chromosomal assay using human lymphocytes. But this method requires too much time and skilled labors to cover the mass victims in radiation emergencies. Electron paramagnetic resonance (EPR) has been known for its capability of quantifying radicals in matters. EPR dosimetry is based on the measurement of stable radiation-induced radicals in tooth enamel. Hydroxyapatite (HAP) (Ca10(PO4)6(OH)2) contained in tooth enamel is a major probe for radiation dose reconstruction. This HAP dosimetry study was performed using a novel EPR spectrometer in Hokkaido University, Japan. The EPR dose-response curve was made using HAP samples. The blind test using 250 cGy samples showed the feasibility of EPR dosimetry for the triage purpose.

  12. Diagnostic radiology dosimetry: status and trends

    Energy Technology Data Exchange (ETDEWEB)

    Rivera M, T., E-mail: trivera@ipn.mx [IPN, Centro de Investigacion en Ciencia Aplicada y Tecnologia Avanzada, Av. Legaria 694, 11500 Mexico D. F. (Mexico)

    2015-10-15

    Full text: Medical radiation is by far the largest man-made source of public exposure to ionizing radiation. Since 1970 the expression of protection standards shifted from a dose- to a risk-based approach, with dose limits established to yield risks to radiation workers comparable with those for workers in other safe industries. Another hand, worldwide interest in patient dose measurement was stimulated by the publication of Patient Dose Reduction in Diagnostic Radiology by the UK National Radiological Protection Board (NRPB). In response to heightened awareness of the importance of patient dose contributed by radiology procedures, there has been a general trend to effect control of patient doses by applying the principles of optimization coupled with an increase in regulatory enforcement. In this sense, thermoluminescent dosimetry (TLD) has been actively proposed in the last 3 decades thanks to their successful applications in diagnostic radiology. At the same time, it is emerged as the best radiation dosimetry method. The present work presents advantages of thermoluminescent dosimetry for X-ray beams measurements and its optimization. (Author)

  13. Reconstructive dosimetry for cutaneous radiation syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Lima, C.M.A.; Lima, A.R.; Degenhardt, Ä.L.; Da Silva, F.C.A., E-mail: dasilva@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Valverde, N.J. [Fundacao Eletronuclear de Assistencia Medica, Rio de Janeiro, RJ (Brazil)

    2015-10-15

    According to the International Atomic Energy Agency (IAEA), a relatively significant number of radiological accidents have occurred in recent years mainly because of the practices referred to as potentially high-risk activities, such as radiotherapy, large irradiators and industrial radiography, especially in gammagraphy assays. In some instances, severe injuries have occurred in exposed persons due to high radiation doses. In industrial radiography, 80 cases involving a total of 120 radiation workers, 110 members of the public including 12 deaths have been recorded up to 2014. Radiological accidents in industrial practices in Brazil have mainly resulted in development of cutaneous radiation syndrome (CRS) in hands and fingers. Brazilian data include 5 serious cases related to industrial gammagraphy, affecting 7 radiation workers and 19 members of the public; however, none of them were fatal. Some methods of reconstructive dosimetry have been used to estimate the radiation dose to assist in prescribing medical treatment. The type and development of cutaneous manifestations in the exposed areas of a person is the first achievable gross dose estimation. This review article presents the state-of-the-art reconstructive dosimetry methods enabling estimation of local radiation doses and provides guidelines for medical handling of the exposed individuals. The review also presents the Chilean and Brazilian radiological accident cases to highlight the importance of reconstructive dosimetry. (author)

  14. Hanford Internal Dosimetry Project manual. Revision 1

    International Nuclear Information System (INIS)

    This document describes the Hanford Internal Dosimetry Project, as it is administered by Pacific Northwest Laboratory (PNL) in support of the US Department of Energy and its Hanford contractors. Project services include administrating the bioassay monitoring program, evaluating and documenting assessment of potential intakes and internal dose, ensuring that analytical laboratories conform to requirements, selecting and applying appropriate models and procedures for evaluating radionuclide deposition and the resulting dose, and technically guiding and supporting Hanford contractors in matters regarding internal dosimetry. Specific chapters deal with the following subjects: practices of the project, including interpretation of applicable DOE Orders, regulations, and guidance into criteria for assessment, documentation, and reporting of doses; assessment of internal dose, including summary explanations of when and how assessments are performed; recording and reporting practices for internal dose; selection of workers for bioassay monitoring and establishment of type and frequency of bioassay measurements; capability and scheduling of bioassay monitoring services; recommended dosimetry response to potential internal exposure incidents; quality control and quality assurance provisions of the program

  15. Current work on dosimetry standards in Japan

    International Nuclear Information System (INIS)

    Basic concepts on standardization of radiation dosimetry are reviewed. The present situation regarding primary standards in the Electrotechnical Laboratory, the primary standard dosimetry laboratory in Japan, is presented, considering the following; (i) Established dosimetric standards of exposure for soft and medium-energy X-rays and gamma rays. This section includes methods of their standardization, and discusses accuracies of instruments operating as environmental-level, protection-level, inspection-level, therapy-level, and processing-level measuring systems. The results of international comparisons between ETL and other, foreign primary standard dosimetry laboratories are presented; (ii) Other established radiation standards related to derivation of radiation absorbed dose. These primary standards include those for the neutron emission rates, thermal and fast neutron flux densities, energy fluences for high-energy photons and electrons, and activities of several kinds of radioactive material. The accuracies and results of international comparisons relating to them are also presented; (iii) Research being carried out at ETL. The current status of the dissemination of radiation standards is presented considering in particular: (i) The calibration services available at ETL, the categories of these services, energy and dose rate ranges, methods, accuracies, etc.; (ii) The calibration services available in certain other organizations considered as SSDLs in Japan, the categories of such work, methods, accuracies etc.; (iii) Present endeavours towards establishing a systematic and effective dissemination system (a so-called Traceability System) in Japan

  16. Factors influencing EPR dosimetry in fingernails

    International Nuclear Information System (INIS)

    The technique based on the detection of ionizing radiation induced radicals by EPR in tooth enamel is an established method for the dosimetry of exposed persons in radiological emergencies. Dosimetry based on EPR spectral analysis of fingernail clippings, currently under development, has the practical advantage of the easier sample collection. A limiting factor is that overlapping the radiation induced signal (RIS), fingernails have shown the presence of two mechanically induced signals, called MIS1 and MIS2, due to elastic and plastic deformation respectively, at the time of fingernails cutting. With a water treatment, MIS1 is eliminated while MIS2 is considerably reduced. The calibration curves needed for radiation accident dosimetry should have 'universal' characteristics, ie. Represent the variability that can be found in different individuals. Early studies were directed to the analysis of factors affecting the development of such universal calibration curves. The peak to peak amplitude of the signal before and after the water treatment as well as the effect of size and number of clippings were studied. Furthermore, the interpersonal and intrapersonal variability were analyzed. Taking into account these previous studies, the optimal conditions for measurement were determined and EPR spectra of samples irradiated at different doses were used for the developing of dose-response curves. This paper presents the analysis of the results.(authors)

  17. EPR dosimetry with tooth enamel: A review

    International Nuclear Information System (INIS)

    When tooth enamel is exposed to ionizing radiation, radicals are formed, which can be detected using electron paramagnetic resonance (EPR) techniques. EPR dosimetry using tooth enamel is based on the (presumed) correlation between the intensity or amplitude of some of the radiation-induced signals with the dose absorbed in the enamel. In the present paper a critical review is given of this widely applied dosimetric method. The first part of the paper is fairly fundamental and deals with the main properties of tooth enamel and some of its model systems (e.g., synthetic apatites). Considerable attention is also paid to the numerous radiation-induced and native EPR signals and the radicals responsible for them. The relevant methods for EPR detection, identification and spectrum analyzing are reviewed from a general point of view. Finally, the needs for solid-state modelling and studies of the linearity of the dose response are investigated. The second part is devoted to the practical implementation of EPR dosimetry using enamel. It concerns specific problems of preparation of samples, their irradiation and spectrum acquisition. It also describes how the dosimetric signal intensity and dose can be retrieved from the EPR spectra. Special attention is paid to the energy dependence of the EPR response and to sources of uncertainties. Results of and problems encountered in international intercomparisons and epidemiological studies are also dealt with. In the final section the future of EPR dosimetry with tooth enamel is analyzed.

  18. Bayesian Methods for Radiation Detection and Dosimetry

    International Nuclear Information System (INIS)

    We performed work in three areas: radiation detection, external and internal radiation dosimetry. In radiation detection we developed Bayesian techniques to estimate the net activity of high and low activity radioactive samples. These techniques have the advantage that the remaining uncertainty about the net activity is described by probability densities. Graphs of the densities show the uncertainty in pictorial form. Figure 1 below demonstrates this point. We applied stochastic processes for a method to obtain Bayesian estimates of 222Rn-daughter products from observed counting rates. In external radiation dosimetry we studied and developed Bayesian methods to estimate radiation doses to an individual with radiation induced chromosome aberrations. We analyzed chromosome aberrations after exposure to gammas and neutrons and developed a method for dose-estimation after criticality accidents. The research in internal radiation dosimetry focused on parameter estimation for compartmental models from observed compartmental activities. From the estimated probability densities of the model parameters we were able to derive the densities for compartmental activities for a two compartment catenary model at different times. We also calculated the average activities and their standard deviation for a simple two compartment model

  19. Quality assurance in radiotherapy dosimetry in China

    International Nuclear Information System (INIS)

    In 1995, the SSDL in the Laboratory of Industrial Hygiene cooperated with Beijing Cancer Hospital, Chinese Academy of Medical science joined the IAEA Co-ordinated Research Programme (NO.8769/RO). According to the requirements of the project, an External Audit Group (EAG) in China was established in 1996 with the responsibilities of operating TLD-based quality audit for radiotherapy dosimetry. Since then. The national TLD dose quality audit services have been carried out in 7 provinces in China. Besides this, the national programmes for brachytherapy and stereostatic radiosurgery (SRS) treatment dosimetry were initiated in 2001. The activity measurement intercomparison between the SSDL and some hospitals for Ir-192 HDR brachytherapy sources has been performed using a HDR well-type ionization chamber (Model HDR 1000 plus) and CDX-2000A Charge Digitizer, which were calibrated in Accredited Dosimetry Calibration Laboratory, University of Wisconsin, USA. The preliminary results indicated that the agreement between SSDL measured activity and hospital stated activity was within ±5% for more than 80% of total participants

  20. Dosimetry and biological effects of fast neutrons

    International Nuclear Information System (INIS)

    This thesis contains studies on two types of cellular damage: cell reproductive death and chromosome aberrations induced by irradiation with X rays, gamma rays and fast neutrons of different energies. A prerequisite for the performance of radiobiological experiments is the determination of the absorbed dose with a sufficient degree of accuracy and precision. Basic concepts of energy deposition by ionizing radiation and practical aspects of neutron dosimetry for biomedical purposes are discussed. Information on the relative neutron sensitivity of GM counters and on the effective point of measurement of ionization chambers for dosimetry of neutron and photon beams under free-in-air conditions and inside phantoms which are used to simulate the biological objects is presented. Different methods for neutron dosimetry are compared and the experimental techniques used for the investigations of cell reproductive death and chromosome aberrations induced by ionizing radiation of different qualities are presented. Dose-effect relations for induction cell inactivation and chromsome aberrations in three cultured cell lines for different radiation qualities are presented. (Auth.)

  1. Acute Bronchitis

    Science.gov (United States)

    ... of bronchitis: acute and chronic. Most cases of acute bronchitis get better within several days. But your cough ... that cause colds and the flu often cause acute bronchitis. These viruses spread through the air when people ...

  2. Bio-dosimetry for radiation-exposed individuals

    International Nuclear Information System (INIS)

    Exposure of civil populations to genotoxic chemicals or radioactive hazard is an increased concern. It is not only an industrial risk (chemistry plant accident for example) but also a national security problem due to the threat of radiological and nuclear terrorism. It is important to anticipate the need of a bio-dosimetry tool aimed at identifying exposed population in the absence of acute syndrome, in order to assure the medical care that would prevent carcinogenic consequences. DNA repair is a bio-marker of exposure to geno-toxics in individuals. A DNA repair signature can be assessed from Peripheral Blood Mononuclear Cells (PBMCs) that reflects the exposure history of the individuals, using a functional enzymatic assay on bio-chip. A proof of concept was obtained using PBMCs from patients undergoing radiotherapy regimen. We identified two classes of responses among patients, if we except a very atypical signature in one patient that could reflect defects in DNA repair. Interestingly, repair of the major oxidative lesions increased during the course of the radiotherapy. We propose to implement this fast, quantitative, possibly automatized assay to identify bio-markers of exposure to geno-toxics and to validate the exposure bio-markers through ex vivo exposure of blood from volunteers. (authors)

  3. The IAEA/WHO thermoluminescent dosimetry intercomparison used for the improvement of clinical dosimetry

    International Nuclear Information System (INIS)

    Results of thermoluminescent dosimetry collected over 5 years in the Eastern Mediterranean region of WHO were analyzed in an attempt to improve clinical dosimetry. Data for 16 radiotherapy departments showed considerable inconsistencies. It was found that the clinical dosemeters used by 3 of the departments were not working properly. The remainder of the departments had one or more dosemeters in perfect working order but the procedure for measuring machine output was inadequate or the correction factors (pressure, temperature) were wrongly applied due to lack of reliable instruments for such measurements. Problems encountered in the sending and returning of TLD dosemeters for assessment are discussed

  4. Reactor Dosimetry State of the Art 2008

    Science.gov (United States)

    Voorbraak, Wim; Debarberis, Luigi; D'Hondt, Pierre; Wagemans, Jan

    2009-08-01

    Oral session 1: Retrospective dosimetry. Retrospective dosimetry of VVER 440 reactor pressure vessel at the 3rd unit of Dukovany NPP / M. Marek ... [et al.]. Retrospective dosimetry study at the RPV of NPP Greifswald unit 1 / J. Konheiser ... [et al.]. Test of prototype detector for retrospective neutron dosimetry of reactor internals and vessel / K. Hayashi ... [et al.]. Neutron doses to the concrete vessel and tendons of a magnox reactor using retrospective dosimetry / D. A. Allen ... [et al.]. A retrospective dosimetry feasibility study for Atucha I / J. Wagemans ... [et al.]. Retrospective reactor dosimetry with zirconium alloy samples in a PWR / L. R. Greenwood and J. P. Foster -- Oral session 2: Experimental techniques. Characterizing the Time-dependent components of reactor n/y environments / P. J. Griffin, S. M. Luker and A. J. Suo-Anttila. Measurements of the recoil-ion response of silicon carbide detectors to fast neutrons / F. H. Ruddy, J. G. Seidel and F. Franceschini. Measurement of the neutron spectrum of the HB-4 cold source at the high flux isotope reactor at Oak Ridge National Laboratory / J. L. Robertson and E. B. Iverson. Feasibility of cavity ring-down laser spectroscopy for dose rate monitoring on nuclear reactor / H. Tomita ... [et al.]. Measuring transistor damage factors in a non-stable defect environment / D. B. King ... [et al.]. Neutron-detection based monitoring of void effects in boiling water reactors / J. Loberg ... [et al.] -- Poster session 1: Power reactor surveillance, retrospective dosimetry, benchmarks and inter-comparisons, adjustment methods, experimental techniques, transport calculations. Improved diagnostics for analysis of a reactor pulse radiation environment / S. M. Luker ... [et al.]. Simulation of the response of silicon carbide fast neutron detectors / F. Franceschini, F. H. Ruddy and B. Petrović. NSV A-3: a computer code for least-squares adjustment of neutron spectra and measured dosimeter responses / J. G

  5. Consensus Through Conversation How to Achieve High-Commitment Decisions

    CERN Document Server

    Dressler, Larry

    2006-01-01

    Facilitation expert Larry Dressler's Consensus Through Conversation is a guide for the effective facilitation and practice of one of business's most popular - but most widely misunderstood - decision-making models: consensus.

  6. Performance testing of dosimetry processors, status of NRC rulemaking for improved personnel dosimetry processing, and some beta dosimetry and instrumentation problems observed by NRC regional inspectors

    International Nuclear Information System (INIS)

    Early dosimetry processor performance studies conducted between 1967 and 1979 by several different investigators indicated that a significant percentage of personnel dosimetry processors may not be performing with a reasonable degree of accuracy. Results of voluntary performance testing of US personnel dosimetry processors against the final Health Physics Society Standard, Criteria for Testing Personnel Dosimetry Performance by the University of Michigan for the Nuclear Regulatory Commission (NRC) will be summarized with emphasis on processor performance in radiation categories involving beta particles and beta particles and photon mixtures. The current status of the NRC's regulatory program for improved personnel dosimetry processing will be reviewed. The NRC is proposing amendments to its regulations, 10 CFR Part 20, that would require its licensees to utilize specified personnel dosimetry services from processors accredited by the National Voluntary Laboratory Accreditation Program of the National Bureau of Standards. Details of the development and schedule for implementation of the program will be highlighted. Finally, selected beta dosimetry and beta instrumentation problems observed by NRC Regional Staff during inspections of NRC licensed facilities will be discussed

  7. Using consensus building to improve utility regulation

    International Nuclear Information System (INIS)

    The utility industry and its regulatory environment are at a crossroads. Utilities, intervenors and even public utility commissions are no longer able to initiate and sustain changes unilaterally. Traditional approaches to regulation are often contentious and costly, producing results that are not perceived as legitimate or practical. Consensus building and alternative dispute resolution have the potential to help utilities, intervenors and regulators resolve a host of regulatory issues. This book traces the decline of consensus in utility regulation and delineates current controversies. It presents the theory and practice of alternative dispute resolution in utility regulation and offers a framework for evaluating the successes and failures of attempts to employ these processes. Four regulatory cases are analyzed in detail: the Pilgrim nuclear power plant outage settlement, the use of DSM collaboratives, the New Jersey resource bidding policy and the formation of integrated resource management rules in Massachusetts

  8. Stochastic stability of continuous time consensus protocols

    OpenAIRE

    Medvedev, Georgi S.

    2010-01-01

    A unified approach to studying convergence and stochastic stability of continuous time consensus protocols (CPs) is presented in this work. Our method applies to networks with directed information flow; both cooperative and noncooperative interactions; networks under weak stochastic forcing; and those whose topology and strength of connections may vary in time. The graph theoretic interpretation of the analytical results is emphasized. We show how the spectral properties, such as algebraic co...

  9. Sarcopenia: European consensus on definition and diagnosis

    OpenAIRE

    Cruz-Jentoft, Alfonso J; Baeyens, Jean Pierre; Bauer, Jürgen M.; Boirie, Yves,; Cederholm, Tommy; Landi, Francesco; Martin, Finbarr C.; Michel, Jean-Pierre; Rolland, Yves; Schneider, Stéphane M.; Topinková, Eva; Vandewoude, Maurits; Zamboni, Mauro

    2010-01-01

    The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four participant organisations, i.e. the European Geriatric Medicine Society, the European Society for Clinical Nutrition and Metabolism, the International Association of Gerontology and Geriatrics—European Region and the International Association of Nutrition and Aging. These organisation...

  10. On Conditions for Convergence to Consensus

    OpenAIRE

    Lorenz, Jan; Lorenz, Dirk A.

    2008-01-01

    A new theorem on conditions for convergence to consensus of a multiagent time-dependent time-discrete dynamical system is presented. The theorem is build up on the notion of averaging maps. We compare this theorem to results by Moreau (IEEE Transactions on Automatic Control, vol. 50, no. 2, 2005) about set-valued Lyapunov theory and convergence under switching communication topologies. We give examples that point out differences of approaches including examples where Moreau's theorem is not a...

  11. Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias

    OpenAIRE

    Mitoma, Hiroshi; Adhikari, Keya; Aeschlimann, Daniel; Chattopadhyay, Partha; Hadjivassiliou, Marios; Hampe, Christiane S.; Honnorat, Jérôme; Joubert, Bastien; Kakei, Shinji; Lee, Jongho; Manto, Mario; Matsunaga, Akiko; Mizusawa, Hidehiro; Nanri, Kazunori; Shanmugarajah, Priya

    2015-01-01

    In the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. In this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. Immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-GAD antibodies, the cerebellar type of Hashimoto’s encephalopathy, primary autoimmune cerebellar ataxia, gluten ataxia, Mi...

  12. A Self-Categorization Explanation for Opinion Consensus Perceptions

    Science.gov (United States)

    Zhang, Jinguang; Reid, Scott A.

    2013-01-01

    The public expression of opinions (and related communicative activities) hinges upon the perception of opinion consensus. Current explanations for opinion consensus perceptions typically focus on egocentric and other biases, rather than functional cognitions. Using self-categorization theory we showed that opinion consensus perceptions flow from…

  13. [Instrumental radiofrequency electromagnetic radiation dosimetry: general principals and modern methodology].

    Science.gov (United States)

    Perov, S Iu; Kudriashov, Iu B; Rubtsova, N B

    2012-01-01

    The modern experimental radiofrequency electromagnetic field dosimetry approach has been considered. The main principles of specific absorbed rate measurement are analyzed for electromagnetic field biological effect assessment. The general methodology of specific absorbed rate automated dosimetry system applied to establish the compliance of radiation sources with the safety standard requirements (maximum permissible levels and base restrictions) is described.

  14. Application of numerical analysis methods to thermoluminescence dosimetry

    International Nuclear Information System (INIS)

    This report presents the application of numerical methods to thermoluminescence dosimetry (TLD), showing the advantages obtained over conventional evaluation systems. Different configurations of the analysis method are presented to operate in specific dosimetric applications of TLD, such as environmental monitoring and mailed dosimetry systems for quality assurance in radiotherapy facilities. (Author) 10 refs

  15. Methods and procedures for internal radiation dosimetry at ORNL

    International Nuclear Information System (INIS)

    Procedures, methods, materials, records, and reports used for accomplishing the personnel, internal radiation monitoring program at Oak Ridge National Laboratory are described for the purpose of documenting what is done now for future reference. This document does not include procedures for nuclear accident dosimetry except insofar as routine techniques may apply also to nuclear accident dosimetry capability

  16. Radiation chemical dosimetry by means of nitrate-nitrite

    International Nuclear Information System (INIS)

    The different chemical systems used in dosimetry and the selection criteria for them are described. The general topics in dosimetry with alkali nitrates as well as the phenomena occurring in their radiolysis are also treated. The possibility of application in dosimetric areas useful in radiosterilization and industrial processes is studied too. (Author) 22 refs

  17. Dosimetry computer module of the gamma irradiator of ININ

    International Nuclear Information System (INIS)

    This work present the technical specifications for the upgrade of the dosimetry module of the computer system of the gamma irradiator of the Instituto Nacional de Investigaciones Nucleares (ININ) whose result allows the integration and consultation of information in industrial dosimetry subject under an outline client-server. (Author)

  18. Neutron dosimetry and radiation damage calculations for HFBR

    Energy Technology Data Exchange (ETDEWEB)

    Greenwood, L.R.; Ratner, R.T. [Pacific Northwest National Lab., TN (United States)

    1998-03-01

    Neutron dosimetry measurements have been conducted for various positions of the High Flux Beam Reactor (HFBR) at Brookhaven National Laboratory (BNL) in order to measure the neutron flux and energy spectra. Neutron dosimetry results and radiation damage calculations are presented for positions V10, V14, and V15.

  19. Present status and expected progress in radiation processing dosimetry

    DEFF Research Database (Denmark)

    Kovács, A.; Miller, A.

    2004-01-01

    The paper describes the present status of radiation processing dosimetry including the methods used most widely in gamma- and electron processing as well as the new methods under development or introduction. The recent trends with respect to calibrationof routine dosimetry systems as well as stan...

  20. Modeling Consensus Semantics in Social Tagging Systems

    Institute of Scientific and Technical Information of China (English)

    Bin Zhang; Yin Zhang; Ke-Ning Gao

    2011-01-01

    In social tagging systems,people can annotate arbitrary tags to online data to categorize and index them.However,the lack of the "a priori" set of words makes it difficult for people to reach consensus about the semantics of tags and how to categorize data.Ontologies based approaches can help reaching such consensus,but they are still facing problems such as inability of model ambiguous and new concepts properly.For tags that are used very few times,since they can only be used in very specific contexts,their semantics are very clear and detailed.Although people have no consensus on these tags,it is still possible to leverage these detailed semantics to model the other tags.In this paper we introduce a random walk and spreading activation like model to represent the semantics of tags using semantics of unpopular tags.By comparing the proposed model to the classic Latent Semantic Analysis approach in a concept clustering task,we show that the proposed model can properly capture the semantics of tags.

  1. Convergence Speed of Binary Interval Consensus

    CERN Document Server

    Draief, Moez

    2012-01-01

    We consider the convergence time for solving the binary consensus problem using the interval consensus algorithm proposed by B\\' en\\' ezit, Thiran and Vetterli (2009). In the binary consensus problem, each node initially holds one of two states and the goal for each node is to correctly decide which one of these two states was initially held by a majority of nodes. We derive an upper bound on the expected convergence time that holds for arbitrary connected graphs, which is based on the location of eigenvalues of some contact rate matrices. We instantiate our bound for particular networks of interest, including complete graphs, paths, cycles, star-shaped networks, and Erd\\" os-R\\' enyi random graphs; for these graphs, we compare our bound with alternative computations. We find that for all these examples our bound is tight, yielding the exact order with respect to the number of nodes. We pinpoint the fact that the expected convergence time critically depends on the voting margin defined as the difference betwe...

  2. Dosimetry Methods of Fast Neutron Using the Semiconductor Diodes

    Science.gov (United States)

    H. Zaki, Dizaji; Kakavand, T.; F. Abbasi, Davani

    2014-01-01

    Semiconductor detectors based on a silicon pin diode are frequently used in the detection of different nuclear radiations. For the detection and dosimetry of fast neutrons, these silicon detectors are coupled with a fast neutron converter. Incident neutrons interact with the converter and produce charged particles that can deposit their energy in the detectors and produce a signal. In this study, three methods are introduced for fast neutron dosimetry by using the silicon detectors, which are: recoil proton spectroscopy, similarity of detector response function with conversion function, and a discriminator layer. Monte Carlo simulation is used to calculate the response of dosimetry systems based on these methods. In the different doses of an 241Am-Be neutron source, dosimetry responses are evaluated. The error values of measured data for dosimetry by these methods are in the range of 15-25%. We find fairly good agreement in the 241Am-Be neutron sources.

  3. EURADOS strategic research agenda: vision for dosimetry of ionising radiation

    International Nuclear Information System (INIS)

    Since autumn 2012, the European Radiation Dosimetry Group (EURADOS) has been developing its Strategic Research Agenda (SRA), which is intended to contribute to the identification of future research needs in radiation dosimetry in Europe. The present article summarises-based on input from EURADOS Working Groups (WGs) and Voting Members-five visions in dosimetry and defines key issues in dosimetry research that are considered important for the next decades. The five visions include scientific developments required towards (a) updated fundamental dose concepts and quantities, (b) improved radiation risk estimates deduced from epidemiological cohorts, (c) efficient dose assessment for radiological emergencies, (d) integrated personalised dosimetry in medical applications and (e) improved radiation protection of workers and the public. The SRA of EURADOS will be used as a guideline for future activities of the EURADOS WGs. A detailed version of the SRA can be downloaded as a EURADOS report from the EURADOS web site (www.eurados.org). (authors)

  4. Performing personnel dosimetry investigations and records quality assurance

    International Nuclear Information System (INIS)

    Radiation Safety Officers (RSOs) sometimes face situations in which personnel dosimetry estimates are required after dosimeters issued to radiation workers (film or TLD badges, extremity dosimeters, etc.) are lost or damaged before processing. This article was prepared to help those involved with personnel dosimetry investigations became aquatinted with this process. A factor that contributes to the anxiety of those unfamiliar with dosimetry investigations is the lack of published guidance available in this subject. More printed resources are needed to help radiation safety professionals familiarize themselves and understand personnel dosimetry investigations. Topics discussed in this presentation include the justification of performing dosimetry investigations, recommendations on how to perform them and the advantages of performing such investigations

  5. Dosimetry on the radiological risks prevention in radiotherapy

    International Nuclear Information System (INIS)

    Dosimetry in its various forms plays a determining role on the radiological risks prevention in radiotherapy. To prove this in this paper is shown an analysis based on the risk matrix method, how the dosimetry can influence in each stages of a radiotherapy service; installation and acceptance, operation, maintenance and calibration. For each one of these stages the role that can play is analyzed as either the initiating event of a radiological accident or limiting barrier of these events of the dosimetric processes used for the individual dosimetry, the area monitoring, fixed or portable, for radiation beam dosimetry and of the patients for a radiotherapy service with cobalt-therapy equipment. The result of the study shows that the application of a prospective approach in the role evaluation of dosimetry in the prevention and mitigation of the consequences of a radiological accident in radiotherapy is crucial and should be subject to permanent evaluation at each development stage of these services. (author)

  6. EURADOS strategic research agenda: vision for dosimetry of ionising radiation.

    Science.gov (United States)

    Rühm, W; Fantuzzi, E; Harrison, R; Schuhmacher, H; Vanhavere, F; Alves, J; Bottollier Depois, J F; Fattibene, P; Knežević, Ž; Lopez, M A; Mayer, S; Miljanić, S; Neumaier, S; Olko, P; Stadtmann, H; Tanner, R; Woda, C

    2016-02-01

    Since autumn 2012, the European Radiation Dosimetry Group (EURADOS) has been developing its Strategic Research Agenda (SRA), which is intended to contribute to the identification of future research needs in radiation dosimetry in Europe. The present article summarises-based on input from EURADOS Working Groups (WGs) and Voting Members-five visions in dosimetry and defines key issues in dosimetry research that are considered important for the next decades. The five visions include scientific developments required towards (a) updated fundamental dose concepts and quantities, (b) improved radiation risk estimates deduced from epidemiological cohorts, (c) efficient dose assessment for radiological emergencies, (d) integrated personalised dosimetry in medical applications and (e) improved radiation protection of workers and the public. The SRA of EURADOS will be used as a guideline for future activities of the EURADOS WGs. A detailed version of the SRA can be downloaded as a EURADOS report from the EURADOS website (www.eurados.org). PMID:25752758

  7. Optimisation of an EPR dosimetry system for robust and high precision dosimetry

    International Nuclear Information System (INIS)

    Clinical applications of electron paramagnetic resonance (EPR) dosimetry systems demand high accuracy causing time consuming analysis. The need for high spatial resolution dose measurements in regions with steep dose gradients demands small sized dosimeters. An optimization of the analysis was therefore needed to limit the time consumption. The aim of this work was to introduce a new smaller lithium formate dosimeter model (diameter reduced from standard diameter 4.5 mm to 3 mm and height from 4.8 mm to 3 mm). To compensate for reduced homogeneity in a batch of the smaller dosimeters, a method for individual sensitivity correction suitable for EPR dosimetry was tested. Sensitivity and repeatability was also tested for a standard EPR resonator and a super high Q (SHQE) one. The aim was also to optimize the performance of the dosimetry system for better efficiency regarding measurement time and precision. A systematic investigation of the relationship between measurement uncertainty and number of readouts per dosimeter was performed. The conclusions drawn from this work were that it is possible to decrease the dosimeter size with maintained measurement precision by using the SHQE resonator and introducing individual calibration factors for dosimeter batches. It was also shown that it is possible reduce the number of readouts per dosimeter without significantly decreasing the accuracy in measurements. - Highlights: • A lithium formate dosimetry system was optimized for accurate dose determinations. • Smaller-sized dosimeters for measurements in dose gradient regions was developed. • Individual sensitivity calibration was introduced for EPR dosimetry. • Measurement precision versus measurement time was evaluated

  8. Dosimetry and process control for food irradiation

    International Nuclear Information System (INIS)

    Whatever a radiation process is designed to achieve, dosimetry is fundamental to it, either as a necessary control, or to establish the process, or for research and development studies. Dosimetry provides the quantitative baseline against which the biological or chemical changes induced by radiation can be measured. In the case of irradiation of food, a minimum dose will be required to achieve the technological objective. A maximum dose will be defined by the onset of the loss of acceptable quality of the food, but upper dose limits will usually be prescribed by regulatory bodies. There is no accurate way of assessing the dose once the food has left the irradiation plant. Therefore the dose must be properly applied and verified during processing. The dose is measured using dosimeters. There are many different types of dosimeters for different applications, dose ranges and conditions of use. All dosimeters must be calibrated, with a measurement traceability chain to a national or international primary standard. This paper describes the classification of dosimeters and gives examples and their applications. Calibration and use of a typical dosimetry system used for food irradiation is then discussed, including the effects of environmental influence factors such as dose rate and temperature, and how measurement traceability can be established. Before routine processing of a product can occur, process qualification must be carried out to ensure the irradiation process produces acceptable results. An example of a dose mapping study is given, followed by discussion of some practical considerations of process control, including measurement uncertainty and how this relates to the setting of process limits

  9. Retrospective accident dosimetry using trapped charges

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. I.; Kim, J. L.; Chang, I.; Kim, B. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Dicentric chromosome aberrations technique scoring of aberrations in metaphases prepared from human lymphocytes is most commonly used. This is considered as a reliable technique because the sample is extracted from the individual human body itself. There are other techniques in biological dosimetry such as Fluorescence In Situ Hybridization (FISH) using translocations, premature chromosome condensation (PCC) and micronucleus assay. However the minimum detectable doses (MDD) are relatively high and sample preparation time is also relatively longer. Therefore, there is limitation in use of these techniques for the purpose of triage in a short time in case of emergency situation relating large number of persons. Electronic paramagnetic resonance (EPR) technique is based on the signal from unpaired electrons such as free radicals in irradiated materials especially tooth enamel, however it has also limitation for the purpose of triage because of difficulty of sample taking and its high MDD. Recently as physical methods, thermoluminescence (TL) and optically stimulated luminescence (OSL) technique have been attracted due to its lower MDD and simplicity of sample preparation. Density of the trapped charges is generally proportional to the radiation dose absorbed and the intensity of emitting light is also proportional to the density of trapped charges, thus it can be applied to measure radiation dose retrospectively. In this presentation, TL and OSL techniques are going to introduced and discussed as physical methods for retrospective accident dosimetry using trapped charges especially in electronic component materials. As a tool for dose reconstruction for emergency situation, thermoluminescece and optically stimulated luminescence techniques which are based on trapped charges during exposure of material are introduced. These techniques have several advantages such as high sensitivity, fast evaluation and ease to sample collection over common biological dosimetry and EPR

  10. Verification of IMRT fields by film dosimetry

    International Nuclear Information System (INIS)

    In intensity modulated radiation therapy (IMRT) the aim of an accurate conformal dose distribution is obtained through a complex process. This ranges from the calculation of the optimal distribution of fluence by the treatment planning system (TPS), to the dose delivery through a multilamellar collimator (MLC), with several segments per beam in the step and shoot approach. The above-mentioned consideration makes mandatory an accurate dosimetric verification of the IM beams. A high resolution and integrating dosimeter, like the radiographic film, permits one to simultaneously measure the dose in a matrix of points, providing a good means of obtaining dose distributions. The intrinsic limitation of film dosimetry is the sensitivity dependence on the field size and on the measurement depth. However, the introduction of a scattered radiation filter permits the use of a single calibration curve for all field sizes and measurement depths. In this paper the quality control procedure developed for dosimetric verification of IMRT technique is reported. In particular a system of film dosimetry for the verification of a 6 MV photon beam has been implemented, with the introduction of the scattered radiation filter in the clinical practice that permits one to achieve an absolute dose determination with a global uncertainty within 3.4% (1 s.d.). The film has been calibrated to be used both in perpendicular and parallel configurations. The work also includes the characterization of the Elekta MLC. Ionimetric independent detectors have been used to check single point doses. The film dosimetry procedure has been applied to compare the measured absolute dose distributions with the ones calculated by the TPS, both for test and clinical plans. The agreement, quantified by the gamma index that seldom reaches the 1.5 value, is satisfying considering that the comparison is performed between absolute doses

  11. Recommendations for the management of biofilm: a consensus document.

    Science.gov (United States)

    Bianchi, T; Wolcott, R D; Peghetti, A; Leaper, D; Cutting, K; Polignano, R; Rosa Rita, Z; Moscatelli, A; Greco, A; Romanelli, M; Pancani, S; Bellingeri, A; Ruggeri, V; Postacchini, L; Tedesco, S; Manfredi, L; Camerlingo, Maria; Rowan, S; Gabrielli, A; Pomponio, G

    2016-06-01

    The potential impact of biofilm on healing in acute and chronic wounds is one of the most controversial current issues in wound care. A significant amount of laboratory-based research has been carried out on this topic, however, in 2013 the European Wound Management Association (EWMA) pointed out the lack of guidance for managing biofilms in clinical practice and solicited the need for guidelines and further clinical research. In response to this challenge, the Italian Nursing Wound Healing Society (AISLeC) initiated a project which aimed to achieve consensus among a multidisciplinary and multiprofessional international panel of experts to identify what could be considered part of 'good clinical practice' with respect to the recognition and management of biofilms in acute and chronic wounds. The group followed a systematic approach, developed by the GRADE working group, to define relevant questions and clinical recommendations raised in clinical practice. An independent librarian retrieved and screened approximately 2000 pertinent published papers to produce tables of levels of evidence. After a smaller focus group had a multistep structured discussion, and a formal voting process had been completed, ten therapeutic interventions were identified as being strongly recommendable for clinical practice, while another four recommendations were graded as being 'weak'. The panel subsequently formulated a preliminary statement (although with a weak grade of agreement): 'provided that other causes that prevent optimal wound healing have been ruled out, chronic wounds are chronically infected'. All members of the panel agreed that there is a paucity of reliable, well-conducted clinical trials which have produced clear evidence related to the effects of biofilm presence. In the meantime it was agreed that expert-based guidelines were needed to be developed for the recognition and management of biofilms in wounds and for the best design of future clinical trials. This is a

  12. Recommendations for the management of biofilm: a consensus document.

    Science.gov (United States)

    Bianchi, T; Wolcott, R D; Peghetti, A; Leaper, D; Cutting, K; Polignano, R; Rosa Rita, Z; Moscatelli, A; Greco, A; Romanelli, M; Pancani, S; Bellingeri, A; Ruggeri, V; Postacchini, L; Tedesco, S; Manfredi, L; Camerlingo, Maria; Rowan, S; Gabrielli, A; Pomponio, G

    2016-06-01

    The potential impact of biofilm on healing in acute and chronic wounds is one of the most controversial current issues in wound care. A significant amount of laboratory-based research has been carried out on this topic, however, in 2013 the European Wound Management Association (EWMA) pointed out the lack of guidance for managing biofilms in clinical practice and solicited the need for guidelines and further clinical research. In response to this challenge, the Italian Nursing Wound Healing Society (AISLeC) initiated a project which aimed to achieve consensus among a multidisciplinary and multiprofessional international panel of experts to identify what could be considered part of 'good clinical practice' with respect to the recognition and management of biofilms in acute and chronic wounds. The group followed a systematic approach, developed by the GRADE working group, to define relevant questions and clinical recommendations raised in clinical practice. An independent librarian retrieved and screened approximately 2000 pertinent published papers to produce tables of levels of evidence. After a smaller focus group had a multistep structured discussion, and a formal voting process had been completed, ten therapeutic interventions were identified as being strongly recommendable for clinical practice, while another four recommendations were graded as being 'weak'. The panel subsequently formulated a preliminary statement (although with a weak grade of agreement): 'provided that other causes that prevent optimal wound healing have been ruled out, chronic wounds are chronically infected'. All members of the panel agreed that there is a paucity of reliable, well-conducted clinical trials which have produced clear evidence related to the effects of biofilm presence. In the meantime it was agreed that expert-based guidelines were needed to be developed for the recognition and management of biofilms in wounds and for the best design of future clinical trials. This is a

  13. Secondary standard dosimetry laboratory at INFLPR

    Energy Technology Data Exchange (ETDEWEB)

    Scarlat, F.; Minea, R.; Scarisoreanu, A.; Badita, E.; Sima, E.; Dumitrascu, M.; Stancu, E.; Vancea, C., E-mail: scarlat.f@gmail.com [National Institute for Laser, Plasma and Radiation Physics - INFLPR, Bucharest (Romania)

    2011-07-01

    National Institute for Laser, Plasma and Radiation Physics (INFLPR) has constructed a High Energy Secondary Standard Dosimetry Laboratory SSDL-STARDOOR - for performing dosimetric calibrations according to ISO IEC SR/EN 17025:2005 standards. This is outfitted with UNIDOS Secondary Standard Dosimeter from PTW (Freiburg Physikalisch-Technische Werksttaten) calibrated at the PTB-Braunschweig (German Federal Institute of Physics and Metrology). A radiation beam of the quality of Q used by our laboratory as calibration source are provided by INFLPR 7 MeV electron beam linear accelerator mounted in our facility. (author)

  14. Eurados trial performance test for photon dosimetry

    DEFF Research Database (Denmark)

    Stadtmann, H.; Bordy, J.M.; Ambrosi, P.;

    2001-01-01

    Within the framework of the EURADOS Action entitled Harmonisation and Dosimetric Quality Assurance in Individual Monitoring for External Radiation, trial performance tests for whole-body and extremity personal dosemeters were carried out. Photon, beta and neutron dosemeters were considered. This...... paper summarises the results of the whole-body photon dosemeter test. Twenty-six dosimetry services from all EU Member States and Switzerland participated. Twelve different radiation fields were used to simulate various workplace irradiation fields. Dose values from 0.4 mSv to 80 mSv were chosen. From...

  15. Thermoluminescent dosimetry and assessment of personal dose

    International Nuclear Information System (INIS)

    Thermoluminescence is discussed in terms of the energy band structure of a crystalline solid and the trapping of charge carriers by point defects. Some general properties of thermoluminescent materials used for dosimetry are outlined, with thermoluminescence of CaSO4:Dy being described in detail. The energy response function and the modification of the energy response of a dosimeter by shielding are discussed. The final section covers the connection between exposure, as recorded by a TLD badge, and the absorbed dose to various organs from gamma radiation in a uranium mine; the conversion from absorbed dose to dose equivalent; and uncertainties in assessment of dose equivalent

  16. The next decade in external dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Griffith, R.V.

    1986-10-01

    As the radiation protection community moves through the last half of the '80s and into the next decade, we can expect the requirements for external dosimetry to become increasingly more restrictive and demanding. As in other health protection fields, growing regulatory and legal pressures, together with a natural evolution in philosophy, require the health physicist to display an increasing degree of accountability, rigor, and professionalism. The good news is that, for the most part, the technology necessary to solve many of the problems will be available or not far behind. This paper describes anticipated technology. 66 refs., 10 figs.

  17. Characterization of new materials for fiberoptic dosimetry

    Science.gov (United States)

    Molina, P.; Santiago, M.; Marcassó, J.; Caselli, E.; Prokic, M.; Khaidukov, N.; Furetta, C.

    2011-09-01

    In this work we have investigated the radioluminescence (RL) characteristics of three materials (Mg2SiO4:Tb, CsY2F7:Tb and KMgF3:Sm) in order to determine whether they can be used as real time dosimeters in the the framework the fiberoptic dosimetry (FOD) technique. This technique is based on the use of scintillating materials coupled to the end of an optical fiber, which collects the light emitted by the scintillator during irradiation. Since usually the intensity of the emitted light is proportional to the dose-rate, the technique provides a reliable measuring method, which can be employed in radiotherapy treatments.

  18. The UK radiotherapy dosimetry audit network

    International Nuclear Information System (INIS)

    Full text: Radiotherapy dosimetry intercomparison in the UK has been carried out in limited studies since the 1960s. However the first national dosimetry intercomparison involving all radiotherapy centres was conducted in the late 1980s. This was based on visits to each centre, using ionisation chamber dosimetry. It audited megavoltage photon beam calibration and other single field parameters. It also measured doses in a three-field 'treatment' in a trapezoidal phantom constructed from epoxy-resin water-equivalent material and compared these to locally planned doses. This included off-axis points, oblique incidence, inhomogeneities, etc. The study found mean measured beam calibration doses close to stated values (ratio 1.003), with a standard deviation (sd) of the distribution of 1.5% and 97% of doses within the pro-set 3% tolerance. For the planned multi-field irradiations, mean dose ratios (measured/stated) were 1.01 (sd 3%, 90% of results within 5%). A number of discrepancies were identified, leading to improved practice. A follow up study (mid-1990s) for electron beam audit also repeated the megavoltage photon calibration audit. For photons, an improvement was noted (mean ratio 1.003, sd 1.0%, 100% within 3%), whilst for electron beams, the mean ratio of measured/stated dose was 0.994 (sd 1.8%, 94% within 3%, 99% within 5%). In parallel with - and growing out of - this, a national audit network began to develop in 1991/2. It utilised similar methodology to the intercomparison and a network approach to allow parallel developments of the scope of the system. The network has eight regional groups, each with up to 10 radiotherapy centres, serving average populations of 7-8 million. Each group organises audits of its own centres and has developed at its own pace. Most have piloted methodology, phantoms, etc. for new audits which can then be used by other groups. All 65 UK centres are included. The network is co-ordinated by an IPEM Steering Committee (current chair

  19. Proton minibeam radiation therapy: Experimental dosimetry evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Peucelle, C.; Martínez-Rovira, I.; Prezado, Y., E-mail: prezado@imnc.in2p3.fr [IMNC-UMR 8165, CNRS, Paris 7 and Paris 11 Universities, 15 rue Georges Clemenceau, Orsay Cedex 91406 (France); Nauraye, C.; Patriarca, A.; Hierso, E.; Fournier-Bidoz, N. [Institut Curie - Centre de Protonthérapie d’Orsay, Campus Universitaire, Bât. 101, Orsay 91898 (France)

    2015-12-15

    Purpose: Proton minibeam radiation therapy (pMBRT) is a new radiotherapy (RT) approach that allies the inherent physical advantages of protons with the normal tissue preservation observed when irradiated with submillimetric spatially fractionated beams. This dosimetry work aims at demonstrating the feasibility of the technical implementation of pMBRT. This has been performed at the Institut Curie - Proton Therapy Center in Orsay. Methods: Proton minibeams (400 and 700 μm-width) were generated by means of a brass multislit collimator. Center-to-center distances between consecutive beams of 3200 and 3500 μm, respectively, were employed. The (passive scattered) beam energy was 100 MeV corresponding to a range of 7.7 cm water equivalent. Absolute dosimetry was performed with a thimble ionization chamber (IBA CC13) in a water tank. Relative dosimetry was carried out irradiating radiochromic films interspersed in a IBA RW3 slab phantom. Depth dose curves and lateral profiles at different depths were evaluated. Peak-to-valley dose ratios (PVDR), beam widths, and output factors were also assessed as a function of depth. Results: A pattern of peaks and valleys was maintained in the transverse direction with PVDR values decreasing as a function of depth until 6.7 cm. From that depth, the transverse dose profiles became homogeneous due to multiple Coulomb scattering. Peak-to-valley dose ratio values extended from 8.2 ± 0.5 at the phantom surface to 1.08 ± 0.06 at the Bragg peak. This was the first time that dosimetry in such small proton field sizes was performed. Despite the challenge, a complete set of dosimetric data needed to guide the first biological experiments was achieved. Conclusions: pMBRT is a novel strategy in order to reduce the side effects of RT. This works provides the experimental proof of concept of this new RT method: clinical proton beams might allow depositing a (high) uniform dose in a brain tumor located in the center of the brain (7.5 cm depth

  20. Monte Carlo simulations for heavy ion dosimetry

    OpenAIRE

    Geithner, Oksana

    2006-01-01

    Water-to-air stopping power ratio ( ) calculations for the ionization chamber dosimetry of clinically relevant ion beams with initial energies from 50 to 450 MeV/u have been performed using the Monte Carlo technique. To simulate the transport of a particle in water the computer code SHIELD-HIT v2 was used which is a substantially modified version of its predecessor SHIELD-HIT v1. The code was partially rewritten, replacing formerly used single precision variables with double precision variabl...

  1. High sensitivity MOSFET-based neutron dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Fragopoulou, M.; Konstantakos, V. [Aristotle University of Thessaloniki, Physics Department, 54124 Thessaloniki (Greece); Zamani, M., E-mail: zamani@physics.auth.g [Aristotle University of Thessaloniki, Physics Department, 54124 Thessaloniki (Greece); Siskos, S.; Laopoulos, T. [Aristotle University of Thessaloniki, Physics Department, 54124 Thessaloniki (Greece); Sarrabayrouse, G. [CNRS, LAAS, 7 avenue du colonel Roche, F-31077 Toulouse (France); Universite de Toulouse, UPS, INSA, INP, ISAE, LAAS, F-31077 Toulouse (France)

    2010-09-21

    A new dosemeter based on a metal-oxide-semiconductor field effect transistor sensitive to both neutrons and gamma radiation was manufactured at LAAS-CNRS Laboratory, Toulouse, France. In order to be used for neutron dosimetry, a thin film of lithium fluoride was deposited on the surface of the gate of the device. The characteristics of the dosemeter, such as the dependence of its response to neutron dose and dose rate, were investigated. The studied dosemeter was very sensitive to gamma rays compared to other dosemeters proposed in the literature. Its response in thermal neutrons was found to be much higher than in fast neutrons and gamma rays.

  2. Worsening renal function in heart failure: the need for a consensus definition.

    Science.gov (United States)

    Sheerin, Noella J; Newton, Phillip J; Macdonald, Peter S; Leung, Dominic Y C; Sibbritt, David; Spicer, Stephen Timothy; Johnson, Kay; Krum, Henry; Davidson, Patricia M

    2014-07-01

    Acute decompensated heart failure is a common cause of hospitalisation. This is a period of vulnerability both in altered pathophysiology and also the potential for iatrogenesis due to therapeutic interventions. Renal dysfunction is often associated with heart failure and portends adverse outcomes. Identifying heart failure patients at risk of renal dysfunction is important in preventing progression to chronic kidney disease or worsening renal function, informing adjustment to medication management and potentially preventing adverse events. However, there is no working or consensus definition in international heart failure management guidelines for worsening renal function. In addition, there appears to be no concordance or adaptation of chronic kidney disease guidelines by heart failure guideline development groups for the monitoring of chronic kidney disease in heart failure. Our aim is to encourage the debate for an agreed definition given the prognostic impact of worsening renal function in heart failure. We present the case for the uptake of the Acute Kidney Injury Network criteria for acute kidney injury with some minor alterations. This has the potential to inform study design and meta-analysis thereby building the knowledgebase for guideline development. Definition consensus supports data element, clinical registry and electronic algorithm innovation as instruments for quality improvement and clinical research for better patient outcomes. In addition, we recommend all community managed heart failure patients have their baseline renal function classified and routinely monitored in accordance with established renal guidelines to help identify those at increased risk for worsening renal function or progression to chronic kidney disease.

  3. Neutron dosimetry for low dose rate Cf-252 AT sources and adherence to recent clinical dosimetry protocol for brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Rivard, M.J.; Wierzbicki, J.G.; Van den Heuvel, F. [Wayne State Univ., Detroit, MI (United States). Dept. of Radiation Oncology; Martin, R.C. [Oak Ridge National Lab., TN (United States). Chemical Technology Div.

    1997-12-01

    In 1995, the American Association of Physicists in Medicine Task Group 43 (AAPM TG-43) published a protocol obsoleting all mixed-field radiation dosimetry for Cf-252. Recommendations for a new brachytherapy dosimetry formalism made by this Task Group favor quantification of source strength in terms of air kerma rather than apparent Curies or other radiation units. Additionally, representation of this dosimetry data in terms of radial dose functions, anisotropy functions, geometric factors, and dose rate constants are in an angular and radial (spherical) coordinate system as recommended, rather than the along-away dosimetry data (Cartesian coordinate system) currently available. This paper presents the initial results of calculated neutron dosimetry in a water phantom for a Cf-252 applicator tube (AT) type medical source soon available from Oak Ridge National Laboratory (ORNL).

  4. International consensus on ANA patterns (ICAP): the bumpy road towards a consensus on reporting ANA results.

    Science.gov (United States)

    Damoiseaux, Jan; von Mühlen, Carlos A; Garcia-De La Torre, Ignacio; Carballo, Orlando Gabriel; de Melo Cruvinel, Wilson; Francescantonio, Paulo Luiz Carvalho; Fritzler, Marvin J; Herold, Manfred; Mimori, Tsuneyo; Satoh, Minoru; Andrade, Luis E C; Chan, Edward K L; Conrad, Karsten

    2016-12-01

    The International Consensus on ANA Patterns (ICAP) was initiated as a workshop aiming to thoroughly discuss and achieve consensus regarding the morphological patterns observed in the indirect immunofluorescence assay on HEp-2 cells. One of the topics discussed at the second ICAP workshop, and addressed in this paper, was the harmonization of reporting ANA test results. This discussion centered on the issue if cytoplasmic and mitotic patterns should be reported as positive or negative. This report outlines the issues that impact on two major different reporting methods. Although it was appreciated by all participants that cytoplasmic and mitotic patterns are clinically relevant, implications for existing diagnostic/classification criteria for ANA-associated diseases in particular hampered a final consensus on this topic. Evidently, a more concerted action of all relevant stakeholders is required. Future ICAP workshops may help to facilitate this action. PMID:26831867

  5. Treatment of Seborrhoeic Dermatitis in Asia: A Consensus Guide.

    Science.gov (United States)

    Cheong, Wai Kwong; Yeung, Chi Keung; Torsekar, Raghunandan Govind; Suh, Dae Hun; Ungpakorn, Rataporn; Widaty, Sandra; Azizan, Noor Zalmy; Gabriel, Maria Teresita; Tran, Hau Khang; Chong, Wei Sheng; Shih, I-Hsin; Dall'Oglio, Federica; Micali, Giuseppe

    2016-05-01

    Seborrhoeic dermatitis (SD) is common in Asia. Its prevalence is estimated to be 1-5% in adults. However, larger population-based studies into the epidemiology of SD in Asia are lacking, and the aetiology of SD may differ widely from Western countries and in different parts of Asia. In addition, clinically significant differences between Asian and Caucasian skin have been reported. There is a need to define standardized clinical diagnostic criteria and/or a grading system to help determine appropriate treatments for SD within Asia. With this in mind, experts from India, South Korea, Taiwan, Malaysia, Vietnam, Singapore, Thailand, the Philippines, Indonesia, and Italy convened to define the landscape of SD in Asia at a meeting held in Singapore. The consensus group developed a comprehensive algorithm to aid clinicians to recommend appropriate treatment of SD in both adults and children. In most cases, satisfactory therapeutic results can be accomplished with topical antifungal agents or topical corticosteroids. Non-steroidal anti-inflammatory agents with antifungal properties have been shown to be a viable option for both acute and maintenance therapy. PMID:27386464

  6. Developing consensus criteria for sarcopenia: an update.

    Science.gov (United States)

    McLean, Robert R; Kiel, Douglas P

    2015-04-01

    Sarcopenia, the age-related loss of muscle mass and strength, is a major cause of impaired physical function, which contributes to mobility disability, falls and hospitalizations in older adults. Lower muscle mass and strength are also associated with lower bone mineral density and greater risk for osteoporotic fractures. Thus, identification of sarcopenia could be important for fracture prevention as it may help improve fracture risk assessment, and muscle mass and strength can be improved with exercise, even among the frailest older adults. Unfortunately, there are no consensus diagnostic criteria for sarcopenia. Consequently there is no guidance to help clinicians identify older adults with clinically meaningful low muscle mass or weakness. Further, development of novel sarcopenia therapies is hindered not only due to the difficulty in identifying participants for clinical trials, and but also because there are no validated, clinically appropriate endpoints for assessment of treatment efficacy. There is currently a major push to establish a consensus definition of sarcopenia, and recent work holds promise that this goal may be within reach. This article discusses the evolution of the definition of sarcopenia, and focuses on the latest recommended diagnostic criteria proposed by the Foundation for the National Institutes of Health (FNIH) Sarcopenia Project. While these empirically-based cut-points for clinically important low muscle mass and weakness are a significant step forward for the sarcopenia field, important questions remain to be answered before consensus diagnostic criteria can be definitively established. Ongoing work to refine sarcopenia criteria will further advance the field and bring this important contributor to falls, fractures and disability into the mainstream of clinical care and ultimately lead to better quality of life with aging.

  7. Eleventh DOE workshop on personnel neutron dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    Since its formation, the Office of Health (EH-40) has stressed the importance of the exchange of information related to and improvements in neutron dosimetry. This Workshop was the eleventh in the series sponsored by the Department of Energy (DOE). It provided a forum for operational personnel at DOE facilities to discuss current issues related to neutron dosimetry and for leading investigators in the field to discuss promising approaches for future research. A total of 26 papers were presented including the keynote address by Dr. Warren K. Sinclair, who spoke on, ``The 1990 Recommendations of the ICRP and their Biological Background.`` The first several papers discussed difficulties in measuring neutrons of different energies and ways of compensating or deriving correction factors at individual facilities. Presentations were also given by the US Navy and Air Force. Current research in neutron dosimeter development was the subject of the largest number of papers. These included a number on the development of neutron spectrometers. Selected papers were processed separately for inclusion in the Energy Science and Technology Database.

  8. DRDC Ottawa working standard for biological dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Segura, T.M.; Prud' homme-Lalonde, L. [Defence Research and Development Canada, Ottawa, Ontario (Canada); Thorleifson, E. [Health Canada, Gatineau, Quebec (Canada); Lachapelle, S.; Mullins, D. [JERA Consulting (Canada); Qutob, S. [Health Canada, Gatineau, Quebec (Canada); Wilkinson, D.

    2005-07-15

    This Standard provides quality assurance, quality control, and evaluation of the performance criteria for the purpose of accreditation of the Radiation Biology laboratory at Defence Research and Development Canada - Ottawa (DRDC Ottawa) using biological dosimetry to predict radiation exposure doses. The International Standard (ISO 19238) and the International Atomic Energy Association (IAEA) Technical Report Series No. 405 are used as guiding documents in preparation of this working document specific to the DRDC Ottawa Radiation Biology Laboratory. This Standard addresses: 1. The confidentiality of personal information, for the customer and the service laboratory; 2. The laboratory safety requirements; 3. The calibration sources and calibration dose ranges useful for establishing the reference dose-effect curves allowing the dose estimation from chromosome aberration frequency, and the minimum detection levels; 4. Transportation criteria for shipping of test samples to the laboratory; 5. Preparation of samples for analysis; 6. The scoring procedure for unstable chromosome aberrations used for biological dosimetry; 7. The criteria for converting a measured aberration frequency into an estimate of absorbed dose; 8. The reporting of results; 9. The quality assurance and quality control plan for the laboratory; and 10. Informative annexes containing examples of a questionnaire, instructions for customers, a data sheet for recording aberrations, a sample report and other supportive documents. (author)

  9. Monte Carlo simulations for heavy ion dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Geithner, O.

    2006-07-26

    Water-to-air stopping power ratio (s{sub w,air}) calculations for the ionization chamber dosimetry of clinically relevant ion beams with initial energies from 50 to 450 MeV/u have been performed using the Monte Carlo technique. To simulate the transport of a particle in water the computer code SHIELD-HIT v2 was used which is a substantially modified version of its predecessor SHIELD-HIT v1. The code was partially rewritten, replacing formerly used single precision variables with double precision variables. The lowest particle transport specific energy was decreased from 1 MeV/u down to 10 keV/u by modifying the Bethe- Bloch formula, thus widening its range for medical dosimetry applications. Optional MSTAR and ICRU-73 stopping power data were included. The fragmentation model was verified using all available experimental data and some parameters were adjusted. The present code version shows excellent agreement with experimental data. Additional to the calculations of stopping power ratios, s{sub w,air}, the influence of fragments and I-values on s{sub w,air} for carbon ion beams was investigated. The value of s{sub w,air} deviates as much as 2.3% at the Bragg peak from the recommended by TRS-398 constant value of 1.130 for an energy of 50 MeV/u. (orig.)

  10. The importance of 3D dosimetry

    International Nuclear Information System (INIS)

    Radiation therapy has been getting progressively more complex for the past 20 years. Early radiation therapy techniques needed only basic dosimetry equipment; motorized water phantoms, ionization chambers, and basic radiographic film techniques. As intensity modulated radiation therapy and image guided therapy came into widespread practice, medical physicists were challenged with developing effective and efficient dose measurement techniques. The complex 3-dimensional (3D) nature of the dose distributions that were being delivered demanded the development of more quantitative and more thorough methods for dose measurement. The quality assurance vendors developed a wide array of multidetector arrays that have been enormously useful for measuring and characterizing dose distributions, and these have been made especially useful with the advent of 3D dose calculation systems based on the array measurements, as well as measurements made using film and portal imagers. Other vendors have been providing 3D calculations based on data from the linear accelerator or the record and verify system, providing thorough evaluation of the dose but lacking quality assurance (QA) of the dose delivery process, including machine calibration. The current state of 3D dosimetry is one of a state of flux. The vendors and professional associations are trying to determine the optimal balance between thorough QA, labor efficiency, and quantitation. This balance will take some time to reach, but a necessary component will be the 3D measurement and independent calculation of delivered radiation therapy dose distributions

  11. Air density correction in ionization dosimetry

    International Nuclear Information System (INIS)

    Air density must be taken into account when ionization dosimetry is performed with unsealed ionization chambers. The German dosimetry protocol DIN 6800-2 states an air density correction factor for which current barometric pressure and temperature and their reference values must be known. It also states that differences between air density and the attendant reference value, as well as changes in ionization chamber sensitivity, can be determined using a radioactive check source. Both methods have advantages and drawbacks which the paper discusses in detail. Barometric pressure at a given height above sea level can be determined by using a suitable barometer, or data downloaded from airport or weather service internet sites. The main focus of the paper is to show how barometric data from measurement or from the internet are correctly processed. Therefore the paper also provides all the requisite equations and terminological explanations. Computed and measured barometric pressure readings are compared, and long-term experience with air density correction factors obtained using both methods is described

  12. DRDC Ottawa working standard for biological dosimetry

    International Nuclear Information System (INIS)

    This Standard provides quality assurance, quality control, and evaluation of the performance criteria for the purpose of accreditation of the Radiation Biology laboratory at Defence Research and Development Canada - Ottawa (DRDC Ottawa) using biological dosimetry to predict radiation exposure doses. The International Standard (ISO 19238) and the International Atomic Energy Association (IAEA) Technical Report Series No. 405 are used as guiding documents in preparation of this working document specific to the DRDC Ottawa Radiation Biology Laboratory. This Standard addresses: 1. The confidentiality of personal information, for the customer and the service laboratory; 2. The laboratory safety requirements; 3. The calibration sources and calibration dose ranges useful for establishing the reference dose-effect curves allowing the dose estimation from chromosome aberration frequency, and the minimum detection levels; 4. Transportation criteria for shipping of test samples to the laboratory; 5. Preparation of samples for analysis; 6. The scoring procedure for unstable chromosome aberrations used for biological dosimetry; 7. The criteria for converting a measured aberration frequency into an estimate of absorbed dose; 8. The reporting of results; 9. The quality assurance and quality control plan for the laboratory; and 10. Informative annexes containing examples of a questionnaire, instructions for customers, a data sheet for recording aberrations, a sample report and other supportive documents. (author)

  13. Radiation Dosimetry Management: Quality Assurance and Investigations

    International Nuclear Information System (INIS)

    Full text: In a litigation-prone society, it is prudent for any business to evaluate its potential exposure to legal action, initiated by either an employee or a member of the general public. This potential is exacerbated when the phobia of radiation exposure and radioactive materials is interjected into the equation. This phobia is fuelled by the perceived risks of radiation exposure, be they fact or fantasy. With the current cancer incidence rate being approximately 1 in every 2.5 individuals (for all types of cancer), it is imperative that all facilities take a proactive look at their business vulnerability. When radiation exposure is the issue, records documentation is a critical factor, and a significant amount of effort should be expended to implement a comprehensive records management system. A comprehensive Radiation Dosimetry Management Program is essential if a business is going to mitigate any regulatory or legal intervention. This lecture will address appropriate Records Quality Assurance, and, the appropriate requirements for investigations of dosimetry results. (author)

  14. Dosimetry methods in boron neutron capture therapy

    Energy Technology Data Exchange (ETDEWEB)

    Gambarini, G.; Artuso, E.; Felisi, M.; Regazzoni, V.; Giove, D. [Universita degli Studi di Milano, Department of Physics, Via Festa del Patrono 7, 20122 Milano (Italy); Agosteo, S.; Barcaglioni, L. [Istituto Nazionale di Fisica Nucleare, Milano (Italy); Campi, F.; Garlati, L. [Politecnico di Milano, Energy Department, Piazza Leonardo Da Vinci 32, 20133 Milano (Italy); De Errico, F. [Universita degli Studi di Pisa, Department of Civil and Industrial Engineering, Lungamo Pacinotti 43, 56126 Pisa (Italy); Borroni, M.; Carrara, M. [Fondazione IRCCS Istituto Nazionale Tumori, Medical Physics Unit, Via Venezian 1, 20133 Milano (Italy); Burian, J.; Klupak, V.; Viererbl, L.; Marek, M. [Research Centre Rez, Department of Neutron Physics, 250-68 Husinec-Rez (Czech Republic)

    2014-08-15

    Dosimetry studies have been carried out at thermal and epithermal columns of Lvr-15 research reactor for investigating the spatial distribution of gamma dose, fast neutron dose and thermal neutron fluence. Two different dosimetry methods, both based on solid state detectors, have been studied and applied and the accuracy and consistency of the results have been inspected. One method is based on Fricke gel dosimeters that are dilute water solutions and have good tissue equivalence for neutrons and also for all the secondary radiations produced by neutron interactions in tissue or water phantoms. Fricke gel dosimeters give the possibility of separating the various dose contributions, i.e. the gamma dose, the fast neutron dose and the dose due to charged particles generated during thermal neutron reactions by isotopes having high cross section, like 10-B. From this last dose, thermal neutron fluence can be obtained by means of the kerma factor. The second method is based on thermoluminescence dosimeters. In particular, the developed method draw advantage from the different heights of the peaks of the glow curve of such phosphors when irradiated with photons or with thermal neutrons. The results show that satisfactory results can be obtained with simple methods, in spite of the complexity of the subject. However, the more suitable dosimeters and principally their utilization and analysis modalities are different for the various neutron beams, mainly depending on the relative intensities of the three components of the neutron field, in particular are different for thermal and epithermal columns. (Author)

  15. Dosimetry of radium-223 and progeny

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R. [Pacific Northwest National Lab., Richland, WA (United States); Sgouros, G. [Memorial Sloan-Kettering Cancer Center, New York, NY (United States)

    1999-01-01

    Radium-223 is a short-lived (11.4 d) alpha emitter with potential applications in radioimmunotherapy of cancer. Radium-223 can be complexed and linked to protein delivery molecules for specific tumor-cell targeting. It decays through a cascade of short-lived alpha- and beta-emitting daughters with emission of about 28 MeV of energy through complete decay. The first three alpha particles are essentially instantaneous. Photons associated with Ra-223 and progeny provide the means for tumor and normal-organ imaging and dosimetry. Two beta particles provide additional therapeutic value. Radium-223 may be produced economically and in sufficient amounts for widescale application. Many aspects of the chemistry of carrier-free isotope preparation, complexation, and linkage to the antibody have been developed and are being tested. The radiation dosimetry of a Ra-223-labeled antibody shows favorable tumor to normal tissue dose ratios for therapy. The 11.4-d half-life of Ra-223 allows sufficient time for immunoconjugate preparation, administration, and tumor localization by carrier antibodies before significant radiological decay takes place. If 0.01 percent of a 37 MBq (1 mCi) injection deposits in a one gram tumor mass, and if the activity is retained with a typical effective half-time (75 h), the absorbed dose will be 163 mGy MBq{sup {minus}1} (600 rad mCi{sup {minus}1}) administered. 49 refs., 5 figs., 2 tabs.

  16. Dosimetry methods in boron neutron capture therapy

    International Nuclear Information System (INIS)

    Dosimetry studies have been carried out at thermal and epithermal columns of Lvr-15 research reactor for investigating the spatial distribution of gamma dose, fast neutron dose and thermal neutron fluence. Two different dosimetry methods, both based on solid state detectors, have been studied and applied and the accuracy and consistency of the results have been inspected. One method is based on Fricke gel dosimeters that are dilute water solutions and have good tissue equivalence for neutrons and also for all the secondary radiations produced by neutron interactions in tissue or water phantoms. Fricke gel dosimeters give the possibility of separating the various dose contributions, i.e. the gamma dose, the fast neutron dose and the dose due to charged particles generated during thermal neutron reactions by isotopes having high cross section, like 10-B. From this last dose, thermal neutron fluence can be obtained by means of the kerma factor. The second method is based on thermoluminescence dosimeters. In particular, the developed method draw advantage from the different heights of the peaks of the glow curve of such phosphors when irradiated with photons or with thermal neutrons. The results show that satisfactory results can be obtained with simple methods, in spite of the complexity of the subject. However, the more suitable dosimeters and principally their utilization and analysis modalities are different for the various neutron beams, mainly depending on the relative intensities of the three components of the neutron field, in particular are different for thermal and epithermal columns. (Author)

  17. Wireless sensor networks distributed consensus estimation

    CERN Document Server

    Chen, Cailian; Guan, Xinping

    2014-01-01

    This SpringerBrief evaluates the cooperative effort of sensor nodes to accomplish high-level tasks with sensing, data processing and communication. The metrics of network-wide convergence, unbiasedness, consistency and optimality are discussed through network topology, distributed estimation algorithms and consensus strategy. Systematic analysis reveals that proper deployment of sensor nodes and a small number of low-cost relays (without sensing function) can speed up the information fusion and thus improve the estimation capability of wireless sensor networks (WSNs). This brief also investiga

  18. Consensus Formation on Simplicial Complex of Opinions

    CERN Document Server

    Maletic, Slobodan

    2012-01-01

    Geometric realization of opinion is considered as a simplex and the opinion space of a group of individuals is a simplicial complex whose topological features are monitored in the process of opinion formation. The agents are physically located on the nodes of the scale-free network. Social interactions include all concepts of social dynamics present in the mainstream models augmented by four additional interaction mechanisms which depend on the local properties of opinions and their overlapping properties. The results pertaining to the formation of consensus are of particular interest. An analogy with quantum mechanical pure states is established through the application of the high dimensional combinatorial Laplacian.

  19. Consensus document on European brain research

    DEFF Research Database (Denmark)

    Di Luca, Monica; Baker, Mary; Corradetti, Renato;

    2011-01-01

    the economic and social challenge posed by management of brain diseases in European countries. To setup a platform for discussion, EBC published in 2006 a Consensus Document on European Brain Research, describing needs and achievements of research in Europe and presenting proposals for future research...... programs. Since 2006, European research in neuroscience has advanced tremendously. The present document represents an update elaborated to reflect changes in research priorities and advances in brain research that have taken place since 2006. The same approach and format have been used here as in the...

  20. Energy consensus talks collapse over nuclear issues

    International Nuclear Information System (INIS)

    Germany's energy consensus talks, ongoing since March 1993, were brought to unsuccessful end on October 26. Representatives from the Social Democratic Party (SDP), led by Lower Saxony's prime minister, Gerhard Schroeder, failed to get approval from party leaders on continued development of advanced reactors with enhanced safety - notably the Siemens/Framatome-designed 1500-MWe European pressurized water reactor (EPR) plan, for which the prospective schedule envisages a construction start in 1998. Nor would the SDP leadership accept the continued operation of existing nuclear plans to the end of their design life (some 20 to 25 years)

  1. Multiple chemical sensitivity: a 1999 consensus.

    Science.gov (United States)

    1999-01-01

    Consensus criteria for the definition of multiple chemical sensitivity (MCS) were first identified in a 1989 multidisciplinary survey of 89 clinicians and researchers with extensive experience in, but widely differing views of, MCS. A decade later, their top 5 consensus criteria (i.e., defining MCS as [1] a chronic condition [2] with symptoms that recur reproducibly [3] in response to low levels of exposure [4] to multiple unrelated chemicals and [5] improve or resolve when incitants are removed) are still unrefuted in published literature. Along with a 6th criterion that we now propose adding (i.e., requiring that symptoms occur in multiple organ systems), these criteria are all commonly encompassed by research definitions of MCS. Nonetheless, their standardized use in clinical settings is still lacking, long overdue, and greatly needed--especially in light of government studies in the United States, United Kingdom, and Canada that revealed 2-4 times as many cases of chemical sensitivity among Gulf War veterans than undeployed controls. In addition, state health department surveys of civilians in New Mexico and California showed that 2-6%, respectively, already had been diagnosed with MCS and that 16% of the civilians reported an "unusual sensitivity" to common everyday chemicals. Given this high prevalence, as well as the 1994 consensus of the American Lung Association, American Medical Association, U.S. Environmental Protection Agency, and the U.S. Consumer Product Safety Commission that "complaints [of MCS] should not be dismissed as psychogenic, and a thorough workup is essential," we recommend that MCS be formally diagnosed--in addition to any other disorders that may be present--in all cases in which the 6 aforementioned consensus criteria are met and no single other organic disorder (e.g., mastocytosis) can account for all the signs and symptoms associated with chemical exposure. The millions of civilians and tens of thousands of Gulf War veterans who

  2. Dosimetry of ionising radiation in modern radiation oncology.

    Science.gov (United States)

    Kron, Tomas; Lehmann, Joerg; Greer, Peter B

    2016-07-21

    Dosimetry of ionising radiation is a well-established and mature branch of physical sciences with many applications in medicine and biology. In particular radiotherapy relies on dosimetry for optimisation of cancer treatment and avoidance of severe toxicity for patients. Several novel developments in radiotherapy have introduced new challenges for dosimetry with small and dynamically changing radiation fields being central to many of these applications such as stereotactic ablative body radiotherapy and intensity modulated radiation therapy. There is also an increasing awareness of low doses given to structures not in the target region and the associated risk of secondary cancer induction. Here accurate dosimetry is important not only for treatment optimisation but also for the generation of data that can inform radiation protection approaches in the future. The article introduces some of the challenges and highlights the interdependence of dosimetric calculations and measurements. Dosimetric concepts are explored in the context of six application fields: reference dosimetry, small fields, low dose out of field, in vivo dosimetry, brachytherapy and auditing of radiotherapy practice. Recent developments of dosimeters that can be used for these purposes are discussed using spatial resolution and number of dimensions for measurement as sorting criteria. While dosimetry is ever evolving to address the needs of advancing applications of radiation in medicine two fundamental issues remain: the accuracy of the measurement from a scientific perspective and the importance to link the measurement to a clinically relevant question. This review aims to provide an update on both of these. PMID:27351409

  3. Dosimetry of ionising radiation in modern radiation oncology

    Science.gov (United States)

    Kron, Tomas; Lehmann, Joerg; Greer, Peter B.

    2016-07-01

    Dosimetry of ionising radiation is a well-established and mature branch of physical sciences with many applications in medicine and biology. In particular radiotherapy relies on dosimetry for optimisation of cancer treatment and avoidance of severe toxicity for patients. Several novel developments in radiotherapy have introduced new challenges for dosimetry with small and dynamically changing radiation fields being central to many of these applications such as stereotactic ablative body radiotherapy and intensity modulated radiation therapy. There is also an increasing awareness of low doses given to structures not in the target region and the associated risk of secondary cancer induction. Here accurate dosimetry is important not only for treatment optimisation but also for the generation of data that can inform radiation protection approaches in the future. The article introduces some of the challenges and highlights the interdependence of dosimetric calculations and measurements. Dosimetric concepts are explored in the context of six application fields: reference dosimetry, small fields, low dose out of field, in vivo dosimetry, brachytherapy and auditing of radiotherapy practice. Recent developments of dosimeters that can be used for these purposes are discussed using spatial resolution and number of dimensions for measurement as sorting criteria. While dosimetry is ever evolving to address the needs of advancing applications of radiation in medicine two fundamental issues remain: the accuracy of the measurement from a scientific perspective and the importance to link the measurement to a clinically relevant question. This review aims to provide an update on both of these.

  4. Acute Pancreatitis and Pregnancy

    Science.gov (United States)

    ... Acute Pancreatitis > Acute Pancreatitis and Pregnancy test Acute Pancreatitis and Pregnancy Timothy Gardner, MD Acute pancreatitis is ... of acute pancreatitis in pregnancy. Reasons for Acute Pancreatitis and Pregnancy While acute pancreatitis is responsible for ...

  5. EPR Dosimetry: an update and prospective studies

    International Nuclear Information System (INIS)

    Electron Paramagnetic Resonance (EPR) technique is useful to quantify the paramagnetic species in any matrix. The unpaired electrons present in paramagnetic materials have non - zero spin value, have an associated spin magnetic moment. When such a system is subjected to an external magnetic field, electronic Zeeman splitting of ground level state occurs. On application of suitable stimulant microwave energy, the electrons flip between the Zeeman levels of ground state, result in resonant absorption of the microwave energy. The intensity of resonant absorption signal is proportional to the concentration of the unpaired electrons in the irradiated material, could lead to possible use of such materials in EPR dosimetric applications. New materials were investigated for EPR dosimetry, wherein the radiation induced paramagnetic species retains the radiation signatures, lead to idea on radiation dose. Few of the materials have been identified as prospective EPR dosimeters. The radiation induced radical in Li2CO3 powder material being paramagnetic in nature (signals at g = 2.0036 and at g 2.0006) and radical concentration varying as a function of irradiation dose, led to its identification for possible use in EPR dosimetric applications. Besides, during the neutron irradiations, the reaction 6Li (n,α) 3H, led to the yield of radicals many folds higher compared to that of gamma irradiation. Thus, the commonly available Li2CO3 material has been assessed for the EPR dosimetric response in gamma and neutron environments. EPR investigation of Li2C2O4, Na2C2O4 mixtures was carried out to measure the radiation dose from γ photons and thermal neutrons in a mixed radiation field. A single line spectrum of CO2- radical at g = 2.0045 ± 0.0005 was found on gamma and neutron irradiations. Of all the mixture combinations, the 2:1 mixture was found more sensitive for gamma / thermal neutrons. Intensity of CO2- radical signal was found linear from 6 Gy - 11 kGy for gamma and 40 - 1500

  6. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2009-08-28

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document.

  7. Dosimetry Modeling for Focal Low-Dose-Rate Prostate Brachytherapy

    International Nuclear Information System (INIS)

    Purpose: Focal brachytherapy targeted to an individual lesion(s) within the prostate may reduce side effects experienced with whole-gland brachytherapy. The outcomes of a consensus meeting on focal prostate brachytherapy were used to investigate optimal dosimetry of focal low-dose-rate (LDR) prostate brachytherapy targeted using multiparametric magnetic resonance imaging (mp-MRI) and transperineal template prostate mapping (TPM) biopsy, including the effects of random and systematic seed displacements and interseed attenuation (ISA). Methods and Materials: Nine patients were selected according to clinical characteristics and concordance of TPM and mp-MRI. Retrospectively, 3 treatment plans were analyzed for each case: whole-gland (WG), hemi-gland (hemi), and ultra-focal (UF) plans, with 145-Gy prescription dose and identical dose constraints for each plan. Plan robustness to seed displacement and ISA were assessed using Monte Carlo simulations. Results: WG plans used a mean 28 needles and 81 seeds, hemi plans used 17 needles and 56 seeds, and UF plans used 12 needles and 25 seeds. Mean D90 (minimum dose received by 90% of the target) and V100 (percentage of the target that receives 100% dose) values were 181.3 Gy and 99.8% for the prostate in WG plans, 195.7 Gy and 97.8% for the hemi-prostate in hemi plans, and 218.3 Gy and 99.8% for the focal target in UF plans. Mean urethra D10 was 205.9 Gy, 191.4 Gy, and 92.4 Gy in WG, hemi, and UF plans, respectively. Mean rectum D2 cm3 was 107.5 Gy, 77.0 Gy, and 42.7 Gy in WG, hemi, and UF plans, respectively. Focal plans were more sensitive to seed displacement errors: random shifts with a standard deviation of 4 mm reduced mean target D90 by 14.0%, 20.5%, and 32.0% for WG, hemi, and UF plans, respectively. ISA has a similar impact on dose-volume histogram parameters for all plan types. Conclusions: Treatment planning for focal LDR brachytherapy is feasible. Dose constraints are easily met with a notable reduction

  8. Dosimetry Modeling for Focal Low-Dose-Rate Prostate Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Al-Qaisieh, Bashar [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Mason, Josh, E-mail: joshua.mason@nhs.net [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Bownes, Peter; Henry, Ann [Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, Leeds (United Kingdom); Dickinson, Louise [Division of Surgery and Interventional Science, University College London, London (United Kingdom); Department of Radiology, Northwick Park Hospital, London North West NHS Trust, London (United Kingdom); Ahmed, Hashim U. [Division of Surgery and Interventional Science, University College London, London (United Kingdom); University College London Hospital, London (United Kingdom); Emberton, Mark [University College London Hospital, London (United Kingdom); Langley, Stephen [St Luke' s Cancer Centre, Guildford (United Kingdom)

    2015-07-15

    Purpose: Focal brachytherapy targeted to an individual lesion(s) within the prostate may reduce side effects experienced with whole-gland brachytherapy. The outcomes of a consensus meeting on focal prostate brachytherapy were used to investigate optimal dosimetry of focal low-dose-rate (LDR) prostate brachytherapy targeted using multiparametric magnetic resonance imaging (mp-MRI) and transperineal template prostate mapping (TPM) biopsy, including the effects of random and systematic seed displacements and interseed attenuation (ISA). Methods and Materials: Nine patients were selected according to clinical characteristics and concordance of TPM and mp-MRI. Retrospectively, 3 treatment plans were analyzed for each case: whole-gland (WG), hemi-gland (hemi), and ultra-focal (UF) plans, with 145-Gy prescription dose and identical dose constraints for each plan. Plan robustness to seed displacement and ISA were assessed using Monte Carlo simulations. Results: WG plans used a mean 28 needles and 81 seeds, hemi plans used 17 needles and 56 seeds, and UF plans used 12 needles and 25 seeds. Mean D90 (minimum dose received by 90% of the target) and V100 (percentage of the target that receives 100% dose) values were 181.3 Gy and 99.8% for the prostate in WG plans, 195.7 Gy and 97.8% for the hemi-prostate in hemi plans, and 218.3 Gy and 99.8% for the focal target in UF plans. Mean urethra D10 was 205.9 Gy, 191.4 Gy, and 92.4 Gy in WG, hemi, and UF plans, respectively. Mean rectum D2 cm{sup 3} was 107.5 Gy, 77.0 Gy, and 42.7 Gy in WG, hemi, and UF plans, respectively. Focal plans were more sensitive to seed displacement errors: random shifts with a standard deviation of 4 mm reduced mean target D90 by 14.0%, 20.5%, and 32.0% for WG, hemi, and UF plans, respectively. ISA has a similar impact on dose-volume histogram parameters for all plan types. Conclusions: Treatment planning for focal LDR brachytherapy is feasible. Dose constraints are easily met with a notable

  9. Meeting Proceedings: Recommendations for Improved Acute Pain Services: Canadian Collaborative Acute Pain Initiative

    Directory of Open Access Journals (Sweden)

    David H Goldstein

    2004-01-01

    Full Text Available The Canadian Collaborative Acute Pain Initiative, established in 2002, is a voluntary, multidisciplinary consortium of acute pain health professionals from across Canada whose goal is to improve acute pain management through discussion and consensus. The group met in January 2002 to define strategic areas related to the treatment of acute pain. The areas identified were: the definition of pain; the epidemiology of pain; the concept of an 'ideal' acute pain management service; education; therapeutic options; symptom management; and research and safety. In November 2002, a second meeting was held to develop objectives and recommendations for the management of acute pain based on the defined areas. The outcome of these discussions is summarized in this paper.

  10. Acute emesis: moderately emetogenic chemotherapy

    DEFF Research Database (Denmark)

    Herrstedt, Jørn; Rapoport, Bernardo; Warr, David;

    2011-01-01

    This paper is a review of the recommendations for the prophylaxis of acute emesis induced by moderately emetogenic chemotherapy as concluded at the third Perugia Consensus Conference, which took place in June 2009. The review will focus on new studies appearing since the Second consensus conference...... version of the guidelines) are as follows: the best prophylaxis in patients receiving moderately emetogenic chemotherapy (not including a combination of an anthracycline plus cyclophosphamide) is the combination of palonosetron and dexamethasone on the day of chemotherapy, followed by dexamethasone...... on days 2-3. In patients receiving a combination of an anthracycline plus cyclophosphamide, a combination of a serotonin(3) receptor antagonist plus dexamethasone, plus the neurokinin(1) receptor antagonist aprepitant on the day of chemotherapy, followed by aprepitant days 2-3, is recommended....

  11. Is acute recurrent pancreatitis a chronic disease?

    Institute of Scientific and Technical Information of China (English)

    Alberto Mariani; Pier Alberto Testoni

    2008-01-01

    Whether acute recurrent pancreaUtis is a chronic disease is still debated and a consensus is not still reached as demonstrated by differences in the classification of acute recurrent pancreatitis.There is major evidence for considering alcoholic pancreatitis as a chronic disease ab initio while chronic pancreatitis lesions detectable in biliary acute recurrent pancreatitis (ARP) seem a casual association.Cystic fibrosis transmembrane con ductance regulator (CFTR) gene mutation,hereditary and obstructive pancreatitis seem an acute disease that progress to chronic pancreatitis,likely as a consequence of the activation and proliferation of pancreatic stellate cells that produce and activate collagen and therefore fibrosis.From the diagnostic point of view,in patients with acute recurrent pancreatitis Endoscopic ultrasound (EUS) seems the more reliable technique for an accurate evaluation and follow-up of some ductal and parenchymal abnormalities suspected for early chronic pancreatitis.

  12. On-Board TL Dosimetry: Possibilities and Limitations

    International Nuclear Information System (INIS)

    Full text: The paper shortly deals with application of TLDs for dosimetry of ISS, e.g. personal dosimetry, phantom measurements, mapping, monitoring and neutron dosimetry. The main characteristics of the on-board and ground evaluation are compared. The main advantages and disadvantages of the on-board evaluation are summarised. Finally the planned future improvements of the Pille system are discussed like development of an RS485 interface for alternative data transfer, introduction of smaller dosimeters (capsules), use of a more use-friendly display (80 characters), application of internal memory instead of memory card and improvement of the dosimeter evaluation (glow curve fit, background subtraction). (author)

  13. Radiation Dosimetry for Quality Control of Food Preservation and Disinfestation

    DEFF Research Database (Denmark)

    McLaughlin, W.L.; Miller, Arne; Uribe, R.M.

    1983-01-01

    In the use of x and gamma rays and scanned electron beams to extend the shelf life of food by delay of sprouting and ripening, killing of microbes, and control of insect population, quality assurance is provided by standardized radiation dosimetry. By strategic placement of calibrated dosimeters...... speed) to meet changes that occur in product and source parameters (e.g. bulk density and radiation spectrum). Routine dosimetry methods and certain corrections of dosimetry data may be selected for the radiations used in typical food processes....

  14. Methods and procedures for external radiation dosimetry at ORNL

    International Nuclear Information System (INIS)

    Procedures, methods, materials, records, and reports used for accomplishing the personnel, external radiation monitoring program at Oak Ridge National Laboratory are described for the purpose of documenting what is done now for future reference. This document provides a description of the methods and procedures for external radiation metering, monitoring, dosimetry, and records which are in effect at ORNL July 1, 1981. This document does not include procedures for nuclear accident dosimetry except insofar as routine techniques may apply also to nuclear accident dosimetry capability

  15. a Decade of Dosimetry for Magnox Reactor Plants

    Science.gov (United States)

    Lewis, T. A.; Thornton, D. A.

    2003-06-01

    This paper reviews the reactor dosimetry program that has supported steel pressure vessel integrity assessments for magnox power plants over the last ten years. The dosimetry program has aimed to achieve consistent:. • calculated and measured fast and thermal neutron doses. • data for surveillance specimens and reactor pressure vessels. Throughout the program, the flux measurements on the plants have been judged essential for any doses where a high degree of confidence is required. The work to support operation is now largely complete and the dosimetry is being extended to assess radioactive inventories as part of the decommissioning process.

  16. The significance and impact of dosimetry audits in radiotherapy

    International Nuclear Information System (INIS)

    Overall, dosimetry audit has improved consistency in radiotherapy results and outcomes for patients and provided confidence to clinicians in the dosimetry supporting their practice. Its importance and impact is clearly recognised and its encouragement of and links to other wider radiotherapy audit has been significant. As it is estimated that a large number of the existing radiotherapy facilities world-wide have not yet participated in some level of independent external dose quality audit, the breadth of uptake of audit is to be encouraged. As the complexity of radiotherapy develops, the scope of what can be included in dosimetry and wider radiotherapy quality audits also needs to continue to increase

  17. The Significance and Impact of Dosimetry Audits in Radiotherapy

    International Nuclear Information System (INIS)

    Overall, dosimetry audit has improved consistency in radiotherapy results and outcomes for patients and provided confidence to clinicians in the dosimetry supporting their practice. Its importance and impact is clearly recognised and its encouragement of and links to other wider radiotherapy audit has been significant. As it is estimated that a large number of the existing radiotherapy facilities world-wide have not yet participated in some level of independent external dose quality audit, the breadth of uptake of audit is to be encouraged. As the complexity of radiotherapy develops, the scope of what can be included in dosimetry and wider radiotherapy quality audits also needs to continue to increase

  18. Radiation Dosimetry for Quality Control of Food Preservation and Disinfestation

    DEFF Research Database (Denmark)

    McLaughlin, W.L.; Miller, Arne; Uribe, R.M.

    1983-01-01

    In the use of x and gamma rays and scanned electron beams to extend the shelf life of food by delay of sprouting and ripening, killing of microbes, and control of insect population, quality assurance is provided by standardized radiation dosimetry. By strategic placement of calibrated dosimeters...... parameters (e.g. conveyor speed) to meet changes that occur in product and source parameters (e.g. bulk density and radiation spectrum). Routine dosimetry methods and certain corrections of dosimetry data may be selected for the radiations used in typical food processes....

  19. Spectrometry and in core dosimetry of neutron radiation. Part I

    International Nuclear Information System (INIS)

    The proceedings contain 8 invited papers discussing current problems of spectrometry and in core neutron dosimetry with regard to applications in nuclear power engineering. The papers deal with the following areas: reactor physics and in core dosimetry; calculations of the spatial and energy distribution of neutrons in the reactor core and shielding; proton-recoil neutron spectrometry; determining neutron spectra with activation detectors; assessment of measurement system used in core dosimetry; in core measurement and monitoring of the reactor radiation field; monitoring the radiation damage to reactor structural materials. (J.P.)

  20. Medical reference dosimetry using EPR measurements of alanine

    DEFF Research Database (Denmark)

    Helt-Hansen, Jakob; Rosendal, F.; Kofoed, I.M.;

    2009-01-01

    Background. Electron spin resonance (EPR) is used to determine the absorbed dose of alanine dosimeters exposed to clinical photon beams in a solid-water phantom. Alanine is potentially suitable for medical reference dosimetry, because of its near water equivalence over a wide energy spectrum, low...... methods the proposed algorithm can be applied without normalisation of phase shifts caused by changes in the g-value of the cavity. The study shows that alanine dosimetry is a suitable candidate for medical reference dosimetry especially for quality control applications....

  1. Implementation of high-dose chemical dosimetry for industrial facilities

    International Nuclear Information System (INIS)

    The purpose of this work is the implementation of methodology for high dose measurements using chemical dosimeters in liquid phase, traceable to the international metrology system, and make available in the country, the standard of high-dose to industrial irradiation facilities and research irradiators, trough the quality program with comparative measurements and direct use of the standard dosimeters in routine. The use of these low cost dosimetry systems in industrial irradiation facilities, assists to the certification requirements and it can reduce the costs with dosimetry for approximately 20% of the total dosimetry costs, using these systems in routine measurements and validation process, largely substituting the imported PMMA dosimeters, among others. (author)

  2. International Consensus On (ICON) Pediatric Asthma

    Science.gov (United States)

    Papadopoulos, N. G.; Arakawa, H.; Carlsen, K.-H.; Custovic, A.; Gern, J.; Lemanske, R.; Le Souef, P.; Makela, M.; Roberts, G.; Wong, G.; Zar, H.; Akdis, C. A.; Bacharier, L. B.; Baraldi, E.; van Bever, H. P.; de Blic, J.; Boner, A.; Burks, W.; Casale, T. B.; Castro-Rodriguez, J. A.; Chen, Y. Z.; El-Gamal, Y. M.; Everard, M. L.; Frischer, T.; Geller, M.; Gereda, J.; Goh, D. Y.; Guilbert, T. W.; Hedlin, G.; Heymann, P. W.; Hong, S. J.; Hossny, E. M.; Huang, J. L.; Jackson, D. J.; de Jongste, J. C.; Kalayci, O.; Khaled, N.; Kling, S.; Kuna, P.; Lau, S.; Ledford, D. K.; Lee, S. I.; Liu, A. H.; Lockey, R. F.; Lodrup-Carlsen, K.; Lotvall, J.; Morikawa, A.; Nieto, A.; Paramesh, H.; Pawankar, R.; Pohunek, P.; Pongracic, J.; Price, D.; Robertson, C.; Rosario, N.; Rossenwasser, L. J.; Sly, P. D.; Stein, R.; Stick, S.; Szefler, S.; Taussig, L. M.; Valovirta, E.; Vichyanond, P.; Wallace, D.; Weinberg, E.; Wennergren, G.; Wildhaber, J.; Zeiger, R. S.

    2015-01-01

    Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Several guidelines and/or consensus documents are available to support medical decisions on pediatric asthma. Although there is no doubt that the use of common systematic approaches for management can considerably improve outcomes, dissemination and implementation of these are still major challenges. Consequently, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), recently formed by the EAACI, AAAAI, ACAAI and WAO, has decided to propose an International Consensus on (ICON) Pediatric Asthma. The purpose of this document is to highlight the key messages that are common to many of the existing guidelines, while critically reviewing and commenting on any differences, thus providing a concise reference. The principles of pediatric asthma management are generally accepted. Overall, the treatment goal is disease control. In order to achieve this, patients and their parents should be educated to optimally manage the disease, in collaboration with health care professionals. Identification and avoidance of triggers is also of significant importance. Assessment and monitoring should be performed regularly to re-evaluate and fine-tune treatment. Pharmacotherapy is the cornerstone of treatment. The optimal use of medication can, in most cases, help patients control symptoms and reduce the risk for future morbidity. The management of exacerbations is a major consideration, independent from chronic treatment. There is a trend towards considering phenotype specific treatment choices; however this goal has not yet been achieved. PMID:22702533

  3. Dosimetry for computed tomography using Fricke gel dosimetry and magnetic resonance imaging

    International Nuclear Information System (INIS)

    In this work it was determined a new method for the determination of absorbed doses in Computed Tomography (CT) examinations using Fricke gel dosimetry developed at IPEN. Absorbed doses were determined by different methods of analysis, such as optical absorption spectrometry, ionization chambers and magnetic resonance imaging. Lower limit of sensitivity of the Fricke gel solution, the solution repeatability signal Fricke gel and CT equipment, detection sensitivity, among other tests were performed. Different equipment of computed tomography with multiple detectors were used. The Fricke gel solution showed better repeatability than ±5.5% using the technique of optical absorption spectrophotometry and computed tomography equipment showed repeatability better than ±0.2%. The Fricke gel solution features an easy and relatively quick preparation, but it is necessary to be careful not to contaminate and lose the solution. With the results, it was confirmed the application of this type of dosimetry for computed tomography equipment. (author)

  4. Bronchitis - acute

    Science.gov (United States)

    ... sharing features on this page, please enable JavaScript. Acute bronchitis is swelling and inflammation in the main passages ... present only for a short time. Causes When acute bronchitis occurs, it almost always comes after having a ...

  5. Acute pancreatitis

    OpenAIRE

    Bo-Guang Fan; Åke Andrén-Sandberg

    2010-01-01

    Background : Acute pancreatitis continues to be a serious illness, and the patients with acute pancreatitis are at risk to develop different complications from ongoing pancreatic inflammation. Aims : The present review is to highlight the classification, treatment and prognosis of acute pancreatitis. Material & Methods : We reviewed the English-language literature (Medline) addressing pancreatitis. Results : Acute pancreatitis is frequently caused by gallstone disease or excess alcohol ingest...

  6. Acute pancreatitis

    OpenAIRE

    Bo-Guang Fan; Åke Andrén-Sandberg

    2010-01-01

    Background: Acute pancreatitis continues to be a serious illness, and the patients with acute pancreatitis are at risk to develop different complications from ongoing pancreatic inflammation. Aims: The present review is to highlight the classification, treatment and prognosis of acute pancreatitis. Material & Methods: We reviewed the English-language literature (Medline) addressing pancreatitis. Results: Acute pancreatitis is frequently caused by gallstone disease or excess alcohol ingestion....

  7. Perioperative acute kidney injury

    Directory of Open Access Journals (Sweden)

    Calvert Stacey

    2012-07-01

    Full Text Available Abstract Acute kidney injury (AKI is a serious complication in the perioperative period, and is consistently associated with increased rates of mortality and morbidity. Two major consensus definitions have been developed in the last decade that allow for easier comparison of trial evidence. Risk factors have been identified in both cardiac and general surgery and there is an evolving role for novel biomarkers. Despite this, there has been no real change in outcomes and the mainstay of treatment remains preventive with no clear evidence supporting any therapeutic intervention as yet. This review focuses on definition, risk factors, the emerging role of biomarkers and subsequent management of AKI in the perioperative period, taking into account new and emerging strategies.

  8. Comparison of Real-Time Intraoperative Ultrasound-Based Dosimetry With Postoperative Computed Tomography-Based Dosimetry for Prostate Brachytherapy

    International Nuclear Information System (INIS)

    Purpose: To evaluate whether real-time intraoperative ultrasound (US)-based dosimetry can replace conventional postoperative computed tomography (CT)-based dosimetry in prostate brachytherapy. Methods and Materials: Between December 2001 and November 2002, 82 patients underwent 103Pd prostate brachytherapy. An interplant treatment planning system was used for real-time intraoperative transrectal US-guided treatment planning. The dose distribution was updated according to the estimated seed position to obtain the dose-volume histograms. Postoperative CT-based dosimetry was performed a few hours later using the Theraplan-Plus treatment planning system. The dosimetric parameters obtained from the two imaging modalities were compared. Results: The results of this study revealed correlations between the US- and CT-based dosimetry. However, large variations were found in the implant-quality parameters of the two modalities, including the doses covering 100%, 90%, and 80% of the prostate volume and prostate volumes covered by 100%, 150%, and 200% of the prescription dose. The mean relative difference was 38% and 16% for doses covering 100% and 90% of the prostate volume and 10% and 21% for prostate volumes covered by 100% and 150% of the prescription dose, respectively. The CT-based volume covered by 200% of the prescription dose was about 30% greater than the US-based one. Compared with CT-based dosimetry, US-based dosimetry significantly underestimated the dose to normal organs, especially for the rectum. The average US-based maximal dose and volume covered by 100% of the prescription dose for the rectum was 72 Gy and 0.01 cm3, respectively, much lower than the 159 Gy and 0.65 cm3 obtained using CT-based dosimetry. Conclusion: Although dosimetry using intraoperative US-based planning provides preliminary real-time information, it does not accurately reflect the postoperative CT-based dosimetry. Until studies have determined whether US-based dosimetry or postoperative CT

  9. Permanent Breast Seed Implant Dosimetry Quality Assurance

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Brian M., E-mail: Brian.Keller@sunnybrook.ca [Department of Medical Physics, Sunnybrook Health Sciences Center, Toronto, ON (Canada); Department of Radiation Oncology, University of Toronto, Sunnybrook Health Sciences Center, Toronto, ON (Canada); Ravi, Ananth [Department of Medical Physics, Sunnybrook Health Sciences Center, Toronto, ON (Canada); Sankreacha, Raxa [Carlo Fidani Regional Cancer Center, Mississauga, ON (Canada); Pignol, Jean-Philippe [Department of Radiation Oncology, University of Toronto, Sunnybrook Health Sciences Center, Toronto, ON (Canada)

    2012-05-01

    Purpose: A permanent breast seed implant is a novel method of accelerated partial breast irradiation for women with early-stage breast cancer. This article presents pre- and post-implant dosimetric data, relates these data to clinical outcomes, and makes recommendations for those interested in starting a program. Methods and Materials: A total of 95 consecutive patients were accrued into one of three clinical trials after breast-conserving surgery: a Phase I/II trial (67 patients with infiltrating ductal carcinoma); a Phase II registry trial (25 patients with infiltrating ductal carcinoma); or a multi-center Phase II trial for patients with ductal carcinoma in situ (3 patients). Contouring of the planning target volume (PTV) was done on a Pinnacle workstation and dosimetry calculations, including dose-volume histograms, were done using a Variseed planning computer. Results: The mean pre-implant PTV coverage for the V{sub 90}, V{sub 100}, V{sub 150}, and V{sub 200} were as follows: 98.8% {+-} 1.2% (range, 94.5-100%); 97.3% {+-} 2.1% (range, 90.3-99.9%), 68.8% {+-} 14.3% (range, 32.7-91.5%); and 27.8% {+-} 8.6% (range, 15.1-62.3%). The effect of seed motion was characterized by post-implant dosimetry performed immediately after the implantation (same day) and at 2 months after the implantation. The mean V{sub 100} changed from 85.6% to 88.4% (p = 0.004) and the mean V{sub 200} changed from 36.2% to 48.3% (p < 0.001). Skin toxicity was associated with maximum skin dose (p = 0.014). Conclusions: Preplanning dosimetry should aim for a V{sub 90} of approximately 100%, a V{sub 100} between 95% and 100%, and a V{sub 200} between 20% and 30%, as these numbers are associated with no local recurrences to date and good patient tolerance. In general, the target volume coverage improved over the duration of the seed therapy. The maximum skin dose, defined as the average dose over the hottest 1 Multiplication-Sign 1-cm{sup 2} surface area, should be limited to 90% of the

  10. A consensus on criteria for cure of acromegaly

    OpenAIRE

    Giustina, Andrea; Chanson, Philippe; Bronstein, M D; Klibanski, A.; Lamberts, Steven; Casanueva, F.F. (Felipe F.); TRAINER, P; Ghigo, Ezio; Ho, K. K. Y.; Melmed, Shlomo

    2010-01-01

    textabstractObjective: The Acromegaly Consensus Group met in April 2009 to revisit the guidelines on criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons and endocrinologists with extensive experience of treating acromegaly. Evidence/Consensus Process: Relevant assays, biochemical measures, clinical outcomes, and definition of disease control were discussed, based on the available published evidence, and the strength of consensus statements was rated. Con...

  11. Average-Consensus Algorithms in a Deterministic Framework

    OpenAIRE

    Topley, Kevin; Krishnamurthy, Vikram

    2011-01-01

    We consider the average-consensus problem in a multi-node network of finite size. Communication between nodes is modeled by a sequence of directed signals with arbitrary communication delays. Four distributed algorithms that achieve average-consensus are proposed. Necessary and sufficient communication conditions are given for each algorithm to achieve average-consensus. Resource costs for each algorithm are derived based on the number of scalar values that are required for communication and ...

  12. Public health crises: the development of a consensus document on their management in Spain.

    Science.gov (United States)

    Rodrigo, T; Caylà, Ja

    2011-01-01

    Several public health crises in Europe have led to sustained outbreaks, political problems, or have generated social alarm. For this reason, a nationwide study was conducted in Spain with the objective to determine which public health events provoke the most frequent crises, to reach a consensus regarding the appropriate actions to be taken when responding to public health crises, and to provide recommendations for their management. The events which had most frequently provoked crises between 1999 and 2004 were identified. A consensus was obtained by public health experts from the 17 Autonomous Regions of Spain and the National Epidemiological Centre using the RAND/UCLA method which combines the Nominal Groups and Delphi techniques. Legionellosis, foodborne diseases, severe acute respiratory syndrome (SARS), bovine spongiform encephalopathy (BSE), bioterrorism, meningococcal meningitis, tuberculosis, heat waves, and influenza epidemics were found to be cause for most public health crises. In Spain, 75% of the crises identified by senior public health experts from the Autonomous Regions involved infectious diseases. Factors triggering a crisis included the type of disease, social alarm, population affected, and the course of action taken by public institutions and reporting in the media. There was consensus that correct information, qualified personnel, availability of standardised protocols for investigation and control, information distribution, and setting up of ‘crisis offices’ were actions with a positive effect regarding crisis resolution. Appropriate management of outbreaks or other situations being perceived as a risk to health can mitigate or even contain the generation of public health crises. PMID:21507319

  13. First aid guidelines for psychosis in Asian countries: A Delphi consensus study

    Directory of Open Access Journals (Sweden)

    Langlands Robyn L

    2008-02-01

    Full Text Available Abstract Background Guidelines for how a member of the public should give first aid to a person who is becoming psychotic have been developed for English-speaking countries. However, these guidelines may not be appropriate for use in other cultures. A study was therefore carried out to examine whether it was possible to achieve consensus on guidelines that could apply in a range of Asian countries. Methods A Delphi consensus study was carried out with a panel of 28 Asian mental health clinicians drawn from Cambodia, China, Hong Kong, Indonesia, Japan, Malaysia, Mongolia, South Korea, Sri Lanka, Taiwan, Thailand and Vietnam. The panel was given a 211 item questionnaire about possible first aid actions and asked to rate whether they thought these should be included in guidelines. Panel members were invited to propose additional items. Results After three Delphi rounds, there were 128 items that were rated as "essential" or "important" by 80% or more of the panel members. These items covered: recognition of psychosis, encouraging and assisting the person to seek help, how to interact with the person, responding to acute psychosis, responding to aggression, and what to do if the person refuses to get professional help. Conclusion Despite the diversity of the countries involved, there was consensus on a core set of first aid items that were considered as suitable for assisting a psychotic person. Future work is needed to develop guidelines for specific countries.

  14. First aid guidelines for psychosis in Asian countries: A Delphi consensus study

    Science.gov (United States)

    Jorm, Anthony F; Minas, Harry; Langlands, Robyn L; Kelly, Claire M

    2008-01-01

    Background Guidelines for how a member of the public should give first aid to a person who is becoming psychotic have been developed for English-speaking countries. However, these guidelines may not be appropriate for use in other cultures. A study was therefore carried out to examine whether it was possible to achieve consensus on guidelines that could apply in a range of Asian countries. Methods A Delphi consensus study was carried out with a panel of 28 Asian mental health clinicians drawn from Cambodia, China, Hong Kong, Indonesia, Japan, Malaysia, Mongolia, South Korea, Sri Lanka, Taiwan, Thailand and Vietnam. The panel was given a 211 item questionnaire about possible first aid actions and asked to rate whether they thought these should be included in guidelines. Panel members were invited to propose additional items. Results After three Delphi rounds, there were 128 items that were rated as "essential" or "important" by 80% or more of the panel members. These items covered: recognition of psychosis, encouraging and assisting the person to seek help, how to interact with the person, responding to acute psychosis, responding to aggression, and what to do if the person refuses to get professional help. Conclusion Despite the diversity of the countries involved, there was consensus on a core set of first aid items that were considered as suitable for assisting a psychotic person. Future work is needed to develop guidelines for specific countries. PMID:18291042

  15. Public health crises: the development of a consensus document on their management in Spain.

    Science.gov (United States)

    Rodrigo, T; Caylà, Ja

    2011-01-01

    Several public health crises in Europe have led to sustained outbreaks, political problems, or have generated social alarm. For this reason, a nationwide study was conducted in Spain with the objective to determine which public health events provoke the most frequent crises, to reach a consensus regarding the appropriate actions to be taken when responding to public health crises, and to provide recommendations for their management. The events which had most frequently provoked crises between 1999 and 2004 were identified. A consensus was obtained by public health experts from the 17 Autonomous Regions of Spain and the National Epidemiological Centre using the RAND/UCLA method which combines the Nominal Groups and Delphi techniques. Legionellosis, foodborne diseases, severe acute respiratory syndrome (SARS), bovine spongiform encephalopathy (BSE), bioterrorism, meningococcal meningitis, tuberculosis, heat waves, and influenza epidemics were found to be cause for most public health crises. In Spain, 75% of the crises identified by senior public health experts from the Autonomous Regions involved infectious diseases. Factors triggering a crisis included the type of disease, social alarm, population affected, and the course of action taken by public institutions and reporting in the media. There was consensus that correct information, qualified personnel, availability of standardised protocols for investigation and control, information distribution, and setting up of ‘crisis offices’ were actions with a positive effect regarding crisis resolution. Appropriate management of outbreaks or other situations being perceived as a risk to health can mitigate or even contain the generation of public health crises.

  16. Operationalising emergency care delivery in sub-Saharan Africa: consensus-based recommendations for healthcare facilities.

    Science.gov (United States)

    Calvello, Emilie J B; Tenner, Andrea G; Broccoli, Morgan C; Skog, Alexander P; Muck, Andrew E; Tupesis, Janis P; Brysiewicz, Petra; Teklu, Sisay; Wallis, Lee; Reynolds, Teri

    2016-08-01

    A major barrier to successful integration of acute care into health systems is the lack of consensus on the essential components of emergency care within resource-limited environments. The 2013 African Federation of Emergency Medicine Consensus Conference was convened to address the growing need for practical solutions to further implementation of emergency care in sub-Saharan Africa. Over 40 participants from 15 countries participated in the working group that focused on emergency care delivery at health facilities. Using the well-established approach developed in the WHO's Monitoring Emergency Obstetric Care, the workgroup identified the essential services delivered-signal functions-associated with each emergency care sentinel condition. Levels of emergency care were assigned based on the expected capacity of the facility to perform signal functions, and the necessary human, equipment and infrastructure resources identified. These consensus-based recommendations provide the foundation for objective facility capacity assessment in developing emergency health systems that can bolster strategic planning as well as facilitate monitoring and evaluation of service delivery. PMID:26202673

  17. [Management strategies and choice of antithrombotic treatment in patients admitted with acute coronary syndrome--executive summary for clinical practice. Consensus Document of the Regional Chapters of the Italian National Association of Hospital Cardiologists (ANMCO) and of the Italian Society of Emergency Medicine (SIMEU)].

    Science.gov (United States)

    Uguccioni, Massimo; Pugliese, Francesco; De Luca, Leonardo; Tubaro, Marco; Ruggieri, Maria Pia; Colivicchi, Furio; Ammirati, Fabrizio; Ansalone, Gerardo; Avella, Andrea; Azzolini, Paolo; Bertazzoni, Giuliano; Brama, Paolo; Cacciatore, Giuseppe; De Luca, Massimo; De Simone, Massimo; Di Fusco, Stefania Angela; Ferraiuolo, Giuseppe; Ferranti, Fabio; Granatelli, Antonino; Loschiavo, Paolo; Mezzanotte, Roberto; Mirante, Enrico; Monti, Francesco; Pajes, Giuseppe; Pandolfo, Luciano; Proiettil, Fabrizio; Revello, Alessandra; Rigattieri, Stefano; Sabetta, Francesco; Sciahbasi, Alessandro; Scioli, Roberto; Serdoz, Roberto; Susi, Beniamino; Vincentelli, Giovanni Maria; Zuccalà, Giuseppe; Zulli, Luigi

    2013-03-01

    This document has been developed by the Lazio regional chapters of two scientific associations, the Italian National Association of Hospital Cardiologists (ANMCO) and the Italian Society of Emergency Medicine (SIMEU), whose members are actively involved in the everyday management of Acute Coronary Syndromes (ACS). The document is aimed at providing a specific, practical, evidence-based guideline for the effective management of antithrombotic treatment (antiplatelet and anticoagulant) in the complex and ever changing scenario of ACS. The document employs a synthetic approach which considers two main issues: the actual operative context of treatment delivery and the general management strategy.

  18. A digital approach to neutron dosimetry and microdosimetry

    International Nuclear Information System (INIS)

    Work has begun in an effort to develop a new, digital approach to neutron dosimetry. In contrast to analogue methods in current use, digital information describes the track of a recoil charged particle produced by a neutron in a gas in terms of the numbers of ions that occur in given volume elements of a detector. It appears that a device based on the time-projection chamber used in particle physics would enable one to measure relevant data for neutron dosimetry. Such an instrument would also furnish data sought in microdosimetry. In this paper we will describe the digital approach to dosimetry and will report on the initial Monte Carlo calculations of the detailed transport of protons and electrons in Ar, CH4, and P-10 gases. These calculations are being used to assess the feasibility of constructing a practical chamber for use in neutron dosimetry and in microdosimetry

  19. External dosimetry in the aftermath of a radiological terrorist event

    International Nuclear Information System (INIS)

    This paper reviews external dosimetry in emergency preparedness planning for a potential terrorist release of radioactive material in a densely populated area. The radiation dose received by response workers and members of the public is needed to understand health risks. The existing framework for dosimetry of routinely occupationally exposed workers is not directly applicable to all emergency workers who would respond to a radiological terrorist event. Emergency preparedness plans incorporate various old and new dosimetry technologies, including quartz fibre electrets, electronic dosemeters, personnel badges and wallet cards. Environmental monitoring and dose calculations are the usual methods for determining public dose. However, during the late-phase response, after removable contamination has been eliminated, it may be easier and more straightforward to provide individual dosimetry for members of the public who may be moving through a city with varying contamination areas. Doing so could allow resumption of normal activities earlier and promote confidence in reusing the site. (authors)

  20. Research on the experimental verification of dosimetry calculations. Progress report

    International Nuclear Information System (INIS)

    This research has been directed toward the development of experimental techniques for the evaluation of internal-dosimetry calculations. There have been three major objectives. The first was the development and refinement of dosimetric techniques necessary to obtain absorbed doses averaged over the entire volume of particular organs. Other major objectives have included the utilization of these dosimetry systems to measure absorbed doses in anthropomorphic phantoms, and the comparison of these experimental results to absorbed dose estimates obtained from Monte Carlo computer calculations. At the present time, only limited data are available for direct comparison. However, more data should be available soon and comparisons will be made before the end of the present contract period. This proposal outlines the current status of our research toward that end. In addition, it is proposed that this contract be renewed to continue investigations into other aspects of dosimetry, for example, dosimetry for the survivors of the bombings of Hiroshima and Nagasaki

  1. Natural dose level determination at Johor State with thermoluminescence dosimetry

    International Nuclear Information System (INIS)

    This paperwork presented the results of using thermoluminescence dosimetry (TLD) method in measuring background dose level, which is done at State of Johor, South Malaysia. The problems faced also discussed

  2. Gamma-ray dosimetry measurements of the Little Boy replica

    Energy Technology Data Exchange (ETDEWEB)

    Plassmann, E.A.; Pederson, R.A.

    1984-01-01

    We present the current status of our gamma-ray dosimetry results for the Little Boy replica. Both Geiger-Mueller and thermoluminescent detectors were used in the measurements. Future work is needed to test assumptions made in data analysis.

  3. Proceedings of the third conference on radiation protection and dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Swaja, R.E.; Sims, C.S.; Casson, W.H. [eds.

    1991-10-01

    The Third Conference on Radiation Protection and Dosimetry was held during October 21--24, 1991, at the Sheraton Plaza Hotel in Orlando, Florida. This meeting was designed with the objectives of promoting communication among applied, research, regulatory, and standards personnel involved in radiation protection, and providing them with sufficient information to evaluate their programs. To meet these objectives, a technical program consisting of more than 75 invited and contributed oral presentations encompassing all aspects of radiation protection was prepared. General topics considered in the technical session included external dosimetry, internal dosimetry, instruments, accident dosimetry, regulations and standards, research advances, and applied program experience. In addition, special sessions were held to afford attendees the opportunity to make short presentations of recent work or to discuss topics of general interest. Individual reports are processed separately on the database.

  4. IAEA Support to National TLD Audit Networks for Radiotherapy Dosimetry

    International Nuclear Information System (INIS)

    For several years, the IAEA has supported the development of methodology and establishment of national quality audit networks for radiotherapy dosimetry. The main objective was to extend the availability of radiotherapy dosimetry audits to as many radiotherapy centres as possible throughout the world. Since 1995, a series of three coordinated research projects (CRPs) has been conducted by the IAEA to assist its Member States to develop such national audit programmes. The first CRP focused on the basic beam calibration audits. The basic programme was extended to audits in non-reference conditions through a second CRP. The third CRP initiated in 2009 is expanding the dosimetry audit tools for more complex techniques used for treatment of cancer patients. The national audit networks participating in these CRPs have incorporated in their programmes procedures for auditing hospital dosimetry for these techniques. (author)

  5. Proceedings of the third conference on radiation protection and dosimetry

    International Nuclear Information System (INIS)

    The Third Conference on Radiation Protection and Dosimetry was held during October 21--24, 1991, at the Sheraton Plaza Hotel in Orlando, Florida. This meeting was designed with the objectives of promoting communication among applied, research, regulatory, and standards personnel involved in radiation protection, and providing them with sufficient information to evaluate their programs. To meet these objectives, a technical program consisting of more than 75 invited and contributed oral presentations encompassing all aspects of radiation protection was prepared. General topics considered in the technical session included external dosimetry, internal dosimetry, instruments, accident dosimetry, regulations and standards, research advances, and applied program experience. In addition, special sessions were held to afford attendees the opportunity to make short presentations of recent work or to discuss topics of general interest. Individual reports are processed separately on the database

  6. Albedo neutron dosimetry in Germany: regulations and performance.

    Science.gov (United States)

    Luszik-Bhadra, M; Zimbal, A; Busch, F; Eichelberger, A; Engelhardt, J; Figel, M; Frasch, G; Günther, K; Jordan, M; Martini, E; Haninger, T; Rimpler, A; Seifert, R

    2014-12-01

    Personal neutron dosimetry has been performed in Germany using albedo dosemeters for >20 y. This paper describes the main principles, the national standards, regulations and recommendations, the quality management and the overall performance, giving some examples. PMID:24639589

  7. Finite-time consensus of heterogeneous multi-agent systems

    Institute of Scientific and Technical Information of China (English)

    Zhu Ya-Kun; Guan Xin-Ping; Luo Xiao-Yuan

    2013-01-01

    We investigate the finite-time consensus problem for heterogeneous multi-agent systems composed of first-order and second-order agents.A novel continuous nonlinear distributed consensus protocol is constructed,and finite-time consensus criteria are obtained for the heterogeneous multi-agent systems.Compared with the existing results,the stationary and kinetic consensuses of the heterogeneous multi-agent systems can be achieved in a finite time respectively.Moreover,the leader can be a first-order or a second-order integrator agent.Finally,some simulation examples are employed to verify the efficiency of the theoretical results.

  8. Imaging of acute pancreatitis and its complications. Part 1: acute pancreatitis.

    Science.gov (United States)

    Türkvatan, A; Erden, A; Türkoğlu, M A; Seçil, M; Yener, Ö

    2015-02-01

    Acute pancreatitis is an acute inflammatory disease of the pancreas that may also involve surrounding tissues or remote organs. The Atlanta classification of acute pancreatitis was introduced in 1992 and divides patients into mild and severe groups based on clinical and biochemical criteria. Recently, the terminology and classification scheme proposed at the initial Atlanta Symposium have been reviewed and a new consensus statement has been proposed by the Acute Pancreatitis Classification Working Group. Generally, imaging is recommended to confirm the clinical diagnosis, investigate the etiology, and grade the extend and severity of the acute pancreatitis. Ultrasound is the first-line imaging modality in most centers for the confirmation of the diagnosis of acute pancreatitis and the ruling out of other causes of acute abdomen, but it has limitations in the acute clinical setting. Computed tomography not only establishes the diagnosis of acute pancreatitis, but also enables to stage severity of the disease. Magnetic resonance imaging has earned an ever more important role in the diagnosis of acute pancreatitis. It is especially useful for imaging of patients with iodine allergies, characterizing collections and assessment of an abnormal or disconnected pancreatic duct. The purpose of this review article is to present an overview of the acute pancreatitis, clarify confusing terminology, underline the role of ultrasound, computed tomography and magnetic resonance imaging according to the proper clinical context and compare the advantages and limitations of each modality.

  9. Surveillance dosimetry of operating power plants

    International Nuclear Information System (INIS)

    The main focus of the research efforts presently underway is the LWR power reactor surveillance program in which metallurgical test specimens of the reactor PV and dosimetry sensors are placed in three or more surveillance capsules at or near the reactor PV inner wall. They are then irradiated in a temperature and neutron flux-spectrum environment as similar as possible to the PV itself for periods of about 1.5 to 15 effective full-power years (EFPY), with removal of the last capsule at a fluence corresponding to the 30- to 40-year plant end-of-life (EOL) fluence. Because the neutron flux level at the surveillance position is greater than at the vessel, the test is accelerated wit respect to the vessel exposure, allowing early assessment of EOL conditions

  10. Course on internal dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    This documentation was distributed to the participants in the Course of Internal Dosimetry in Nuclear Medicine organised by the Nuclear Regulatory Authority (ARN) of Argentina and held in Buenos Aires, Argentina, August 9-13, 2004. The course was intended for people from IAEA Member States in the Latin American and Caribbean region, and for professionals and workers in medicine, related with the radiation protection. Spanish and English were the languages of the course. The following subjects were covered: radioprotection of the patient in nuclear medicine; injuries by ionizing radiations; MIRD methodology; radiation dose assessment in nuclear medicine; small scale and microdosimetry; bone and marrow dose modelling; medical internal dose calculations; SPECT and image reconstruction; principles of the gamma camera; scattering and attenuation correction in SPECT; tomography in nuclear medicine

  11. Internal Dosimetry for Nuclear Power Program

    International Nuclear Information System (INIS)

    Internal dosimetry which refers to dosage estimation from internal part of an individual body is an important and compulsory component in order to ensure the safety of the personnel involved in operational of a Nuclear Power Program. Radionuclides particle may deposit in the human being through several pathways and release wave and/or particle radiation to irradiate that person and give dose to body until it been excreted or completely decayed from the body. Type of radionuclides of concerning, monitoring program, equipment's and technique used to measure the concentration level of such radionuclides and dose calculation will be discussed in this article along with the role and capability of Malaysian Nuclear Agency. (author)

  12. The micronucleus test in biological dosimetry

    International Nuclear Information System (INIS)

    The determination of micronuclei in lymphocytes on the basis of the Cytochalasine B method may already be regarded as a most useful tool following short-term wholebody exposure to doses in the range between approx. 0.3 and 7 Gy and thus offers a genuine alternative to the conventional analysis of chromosomes. Further efforts in the research on micronuclei as a biological system of dosimetry should primarily be made in the field of radiosensitive subpopulations and, additionally, the field of automated evaluation procedures. It is to be expected that this will permit the limit of detection to be lowered to doses of even less than approx. 0.2 - 0.3 Gy. (orig.)

  13. Polymer gel dosimetry system for radiation therapy

    International Nuclear Information System (INIS)

    Purpose/Objective: Recently developed treatment modalities such as stereotactic and conformal radiation therapy produce complex dose distributions which are difficult or impractical to measure with conventional dosimetry instrumentation. Three-dimensional treatment planning systems which purport to calculate these complex dose distributions should be compared to experimental results before being routinely applied to clinical problems. There is a need for a new class of tissue-equivalent dosimeters capable of providing accurate, high resolution, time-integrated and three dimensional dose distributions. The recently developed BANG polymer gel dosimetry system (MGS Research, Inc., Guilford, CT) is ideally suited for the task described above. Physico-chemical principles of the polymer gel dosimetry are presented, together with examples of its application to radiation therapy. Data analysis and display program, written for Macintosh computer, is demonstrated. Materials and Methods: Radiation-induced polymerization of acrylic monomers, which are dispersed in tissue-equivalent gelatin, has been shown to be dependent on the dose, but independent of the dose rate or photon energy. Therefore, the spatial distribution of polymer in the gel is precisely representative of the dose distribution. As the polymeric microparticles reduce the water proton NMR relaxation times in the gel, the dose distribution can be measured with high resolution and accuracy using magnetic resonance imaging. Also, as these microparticles cannot diffuse through the gelatin matrix, their distribution is permanent. An improved formulation of the BANG dosimeter consists of 3% w/v acrylic acid, 3% N,N'-methylene-bis-acrylamide, 1% sodium hydroxide, 5% gelatin, and 88% water. MR images are transferred via a local network to a Macintosh computer, and R2 maps constructed on the basis of multiple TE images, using a non-linear least squares fit based on the Levenberg-Marquardt algorithm. A dose-to-R2

  14. Applied internal dosimetry staff exposed to Uranium

    International Nuclear Information System (INIS)

    Dosimetric calculations are performed in order to estimate the quantity of a radionuclide that is incorporated by a worker. Urine determinations of activity and mass of uranium are made in the laboratory of Personal and Area Dosimetry. The paper presents reference values concerning the activity excreted in urine due to the incorporation of uranium compounds. The compounds analyzed are natural uranium and uranium enriched to 20 %, both soluble and insoluble. According to the limits allowed for the incorporation of uranium compounds of Type F and M, we verify that the times of monitoring and the detection limits of the equipment used to determine the activity are appropriate. On the other hand, the S-type compounds determination in urine is useful in cases of accidental incorporations (above the ALI) as a first and quick estimate; MDA (0.017 Bq / L) does not allow detection in routine monitoring; measurement in lungs, and faeces should be included. (author)

  15. A human head phantom for experimental dosimetry

    International Nuclear Information System (INIS)

    In order to achieve a better understanding of the behavior of nuclear particles in a human head experiment a phantom preserving similar tissues as well as similar anthropomorphic characteristics was used. In this work a biologic equivalent tissue material was developed, maintaining the chemical composition and tissue density, based on enriched PMMA. A humanoid head phantom was built using a human skull as a base, donated by the Morphology Department of the Institute for Biologic Sciences-ICB/UFMG. Muscles were replaced with biologic equivalent tissue material following anatomic precepts. The phantom presents: formalized animal salivary glands, brain and submandibular lymph nodes; human teeth; hair; prosthetic eyes and nose as well as human equivalent skin containing silicone and animal collagen. This phantom present several important conditions as human morphological characteristics, equivalent biological tissue and the head bone structure. It will be used in radiotherapy and brachytherapy studies, dosimetry and quality control of medical diagnostic image. (author)

  16. Radiation protection and dosimetry: basis. 9. ed.

    International Nuclear Information System (INIS)

    A revised book 'Radiation Protection and Dosimetry: Fundamentals, prepared to meet the training courses offered by the Instituto de Radioprotecao e Dosimetria - IRD, Rio de Janeiro, RJ, Brazil and people interested in the subject, is presented. Concepts have been updated, especially the chapter on Radiological Magnitudes, due to upgrade of Standard CNEN-NN-3.01-Basic Guidelines on Radiological Protection, published in the Diario Oficial da Uniao on September 1, 2011. A chapter related to Waste Management, another on the Transport of Radioactive Materials and three annexes on: Standards of CNEN, Ionizing Radiation and Personnel Legislation and Determination of shields in Radiotherapy were included. Were also added several tables for use in radiological protection, to facilitate consultation

  17. The radiation dosimetry of intrathecally administered radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Stabin, M.G. [Oak Ridge Inst. for Science and Education, TN (United States); Evans, J.F. [Ohio State Univ., Columbus, OH (United States)

    1999-01-01

    The radiation dose to the spine, spinal cord, marrow, and other organs of the body from intrathecal administration of several radiopharmaceuticals was studied. Anatomic models were developed for the spine, spinal cerebrospinal fluid (CSF), spinal cord, spinal skeleton, cranial skeleton, and cranial CSF. A kinetic model for the transport of CSF was used to determine residence times in the CSF; material leaving the CSF was thereafter assumed to enter the bloodstream and follow the kinetics of the radiopharmaceutical as if intravenously administered. The radiation transport codes MCNP and ALGAMP were used to model the electron and photon transport and energy deposition. The dosimetry of Tc-99m DTPA and HSA, In-111 DTPA, I-131 HSA, and Yb-169 DTPA was studied. Radiation dose profiles for the spinal cord and marrow in the spine were developed and average doses to all other organs were estimated, including dose distributions within the bone and marrow.

  18. Skin dosimetry with new MOSFET detectors

    Energy Technology Data Exchange (ETDEWEB)

    Kwan, I.S.; Rosenfeld, A.B. [Centre for Medical Radiation Physics, University of Wollongong, Northfields Ave., Wollongong (Australia); Qi, Z.Y. [Centre for Medical Radiation Physics, University of Wollongong, Northfields Ave., Wollongong (Australia); Radiation Oncology Department, Cancer Center, Sun Yat-Sen University, Guangzhou (China); Wilkinson, D.; Lerch, M.L.F. [Centre for Medical Radiation Physics, University of Wollongong, Northfields Ave., Wollongong (Australia); Cutajar, D.L. [Centre for Medical Radiation Physics, University of Wollongong, Northfields Ave., Wollongong (Australia)], E-mail: deanc@uow.edu.au; Safavi-Naeni, M. [Centre for Medical Radiation Physics, University of Wollongong, Northfields Ave., Wollongong (Australia); Butson, M. [Illawarra Cancer Care Centre, Wollongong Hospital, Crown Street, Wollongong (Australia); Bucci, J.A.; Chin, Y. [St. George Cancer Care Centre, St. George Hospital, Kogarah (Australia); Perevertaylo, V.L. [SPA BIT (Ukraine)

    2008-02-15

    The MOSkin, a new MOSFET-based detector designed by the Centre for Radiation Physics, was engineered to provide accurate measurements of skin doses in radiotherapy and personal monitoring. The International Commission on Radiological Protection (ICRP) estimates the radiosensitive basal layer to be at an average depth of 0.070 mm. Current commercially available MOSFETs utilize an epoxy bubble encapsulation, making measurements at equivalent depths of 0.070 mm difficult. The MOSkin utilizes a novel packaging design that allows the measurement of doses at this equivalent depth. The MOSkin has shown excellent agreement with the Attix chamber for surface measurements in a 6 MV photon beam of various field sizes and has minimal angular dependence due to the encapsulation. The new design will diversify the use of MOSFETs for dosimetry in radiotherapy and radiation protection.

  19. Dosimetry for radiocolloid therapy of cystic craniopharyngiomas

    CERN Document Server

    Rojas, E L; Lallena, A M; Bodineau, C; Galan, P; Al-Dweri, Feras M.O.; Lallena, Antonio M.; Bodineau, Coral; Galan, Pedro

    2003-01-01

    The dosimetry for radiocolloid therapy of cystic craniopharyngiomas is investigated. Analytical calculations based on the Loevinger and the Berger formulae for electrons and photons, respectively, are compared with Monte Carlo simulations. The role of the material of which the colloid introduced inside the craniopharyngioma is made of as well as that forming the cyst wall is analyzed. It is found that the analytical approaches provide a very good description of the simulated data in the conditions where they can be applied (i.e., in the case of a uniform and infinite homogeneous medium). However, the consideration of the different materials and interfaces produces a strong reduction of the dose delivered to the cyst wall in relation to that predicted by the Loevinger and the Berger formulae.

  20. Bone marrow dosimetry via microCT imaging and stem cell spatial mapping

    Science.gov (United States)

    Kielar, Kayla N.

    In order to make predictions of radiation dose in patients undergoing targeted radionuclide therapy of cancer, an accurate model of skeletal tissues is necessary. Concerning these tissues, the dose-limiting factor in these therapies is the toxicity of the hematopoietically active bone marrow. In addition to acute effects, one must be concerned as well with long-term stochastic effects such as radiation-induced leukemia. Particular cells of interest for both toxicity and cancer risk are the hematopoietic stem cells (HSC), found within the active marrow regions of the skeleton. At present, cellular-level dosimetry models are complex, and thus we cannot model individual stem cells in an anatomic model of the patient. As a result, one reverts to looking at larger tissue regions where these cell populations may reside. To provide a more accurate marrow dose assessment, the skeletal dosimetry model must also be patient-specific. That is, it should be designed to match as closely as possible to the patient undergoing treatment. Absorbed dose estimates then can be tailored based on the skeletal size and trabecular microstructure of an individual for an accurate prediction of marrow toxicity. Thus, not only is it important to accurately model the target tissues of interest in a normal patient, it is important to do so for differing levels of marrow health. A skeletal dosimetry model for the adult female was provided for better predictions of marrow toxicity in patients undergoing radionuclide therapy. This work is the first fully established gender specific model for these applications, and supersedes previous models in scalability of the skeleton and radiation transport methods. Furthermore, the applicability of using bone marrow biopsies was deemed sufficient in prediction of bone marrow health, specifically for the hematopoietic stem cell population. The location and concentration of the HSC in bone marrow was found to follow a spatial gradient from the bone trabeculae

  1. Extremity dosimetry at US Department of Energy facilities

    International Nuclear Information System (INIS)

    A questionnaire on extremity dosimetry was distributed to DOE facilities along with a questionnaire on beta dosimetry. An informal telephone survey was conducted as a follow-up survey to answer a few additional questions concerning extremity monitoring practices. The responses to the questionnaire and the telephone survey are summarized in this report. Background information, developed from operational experience and a review of the current literature, is presented as a basis for understanding the information obtained by the survey and questionnaire

  2. General guidance for laboratories providing personal dosimetry services

    International Nuclear Information System (INIS)

    This guidance is recommended to all dosimetry services in the interests of good radiation protection practice. For dosimetry services who seek approval under the Ionising Radiation Regulations 1985, the Health and Safety Executive (HSE) would invoke compliance with this guidance, in broad terms, as well as other published guidance. The recommendations include sections concerning laboratory organizations and staff, documentation of procedures, laboratory accommodation and services, equipment, calibration and traceability, housekeeping, dosimetric capability, laboratory records. (Author)

  3. Free form source representation for a VR dosimetry training application

    OpenAIRE

    MOLTO CARACENA Teofilo; Goncalves, Joao; Peerani, Paolo; Vendrell Vidal, Eduardo

    2013-01-01

    A method to model free form nuclear sources in Virtual Reality (VR) based dosimetry applications for training purposes is presented in this paper. A VR based dosimetry application can provide advantages in terms of time, cost and logistics with respect to traditional on-site training courses, representing a valid complement to the traditional ones. In order to benefit from these advantages, methods need to be developed to overcome the requirements such a VR application requires, such as real...

  4. The personnel dosimetry record keeping system at AEE Winfrith

    International Nuclear Information System (INIS)

    Since May 1978 the exposure of personnel to external radiation has been assessed by Thermoluminescent Dosimetry, (TLD). The dosemeter consists of a TLD card similar to that used by the National Radiological Protection Board, held in a plastic badge designed at AEE Winfrith, and used in conjunction with a D A Pitman Ltd Type 605 Automatic Reader. The report describes the dosemeter, the operation of the dosimetry service and the system for maintaining a computerised record keeping system. (author)

  5. Development of TLD audits for radiotherapy dosimetry in Argentina

    International Nuclear Information System (INIS)

    Since 1978 the Regional Reference Center for Dosimetry in Argentina (Secondary Standard Dosimetry Laboratory belonging to the IAEA-WHO SSDLs Network) has been performing a dose intercomparison programme for cobalt 60 therapy units operating in the country. Applied methodology was similar to that of the IAEA TLD audit service and the dose at a reference point on the radiation beam axis was checked by this programme. The results of this audits showed that dose deviations obtained were within the acceptance limits

  6. Why is a high accuracy needed in dosimetry. [Radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Lanzl, L.H.

    1976-01-01

    Dose and exposure intercomparisons on a national or international basis have become an important component of quality assurance in the practice of good radiotherapy. A high degree of accuracy of ..gamma.. and x radiation dosimetry is essential in our international society, where medical information is so readily exchanged and used. The value of accurate dosimetry lies mainly in the avoidance of complications in normal tissue and an optimal degree of tumor control.

  7. Dosimetry needs for the Magnetic Fusion Materials Program

    International Nuclear Information System (INIS)

    The significance of neutron dosimetry within the MFE materials program is discussed. Experimental results demonstrating the current MFE dosimetry methodology is presented for facilities such as RTNS-I and Be(d,n) facilities. Brief descriptions of planned facilities for high intensity neutron sources are given and experimental data needs are stressed. The potential use of nuclear emulsion techniques for these facilities is discussed

  8. In vivo dosimetry during tangential breast treatment

    Energy Technology Data Exchange (ETDEWEB)

    Heukelom, S.; Lanson, J.H.; Tienhoven, G. van; Mijnheer, B.J. (Nederlands Kanker Inst. ' Antoni van Leeuwenhoekhuis' , Amsterdam (Netherlands))

    1991-12-01

    Three-dimensional (3-D) dose distribution as calculated in clinical practice for tangential breast treatment was verified through in vivo dosimetry. Clinical practice at Netherlands Cancer Institute implies use of 8MV X-ray beams, 2-D treatment planning system, collimator rotation and a limited set of patient data for dose calculations. By positioning diodes at the central beam axes as well as in the periphery of the breast the magnitude of dose values at the isocentre and in points situated in high-dose regions behind the lung could be assessed. The position of diodes was verified by means of an on-line portal imaging device. Reproducibility of these in vivo dose measurements was better than 2% (1SD). This study shows that on the average dose delivery at the isocentre is 2% less at the points behind the lung, 5.7% higher with respect to the calculated dose values. Detailed analysis of these in vivo dosimetry results, based on dose measurements performed with a breast shaped phantom, yielded the magnitudes of errors in predicted dose due to several limitations in dose calculation algorithms and dose calculation procedure. These limitations are each introducing an error of several percent but are compensating each other for the dose calculation at the isocentre. It is concluded that dose distribution in patient for this treatment technique and dose calculation procedure can be predicted with a 2-D treatment planning system in an acceptable way. A more accurate prediction of dose distribution can be performed but requires an estimation of the lack of scatter due to missing tissue, the change in the dose distribution due to oblique incident beams and incorporation of the actual output of the treatment machine in the assessment of the number of monitor units. (author). 28 refs.; 3 figs.; 4 tabs.

  9. Neutron spectrometry and dosimetry using NSDAAN

    International Nuclear Information System (INIS)

    The reconstruction of neutron spectra from count rates of a Bonner spheres spectrometric system is performed using various methods such as Monte Carlo methods, the parameterization and iterative methods. The weight of the Bonner spheres spectrometric system, the procedure for the reconstruction of the spectra, the need of an experienced user, the high consumer of time, the need of use a reconstruction code as the BUNKI, SAND, among others, and the resolution of the spectrum are some problems that this system presents. This has motivated the development of complementary procedures such as maximum entropy, genetic algorithms and artificial neural networks. In previous work, has reported a new method called robust design methodology of artificial neural networks, to construct various network topologies capable of solving the problems of neutron spectrometry and dosimetry, however, due to the newness of this technology, be noted that there are not tools to end-user that allow test and validate the designed networks. This paper presents a software for the neutron spectrometry and dosimetry, designed from the information extracted of an artificial neural network designed by robust design methodology of artificial neural networks. This tool has the following characteristics: was designed in a user graphical interface easy to use, requires not knowledge of neural networks or neutron spectrometry by the user; execution speed of the application; unlike the deconvolution codes are not required to select an initial spectrum for the spectrum reconstruction; as an additional element to this tool, besides the spectrum, the calculation is performed simultaneous to H(10), E, Hp,s(10,θ) from just counting rates from a Bonner spheres spectrometric system. (author)

  10. Latest developments in silica fibre luminescence dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D. A.; Abdul S, S. F.; Jafari, S. M.; Alanazi, A. [University of Surrey, Department of Physics, GU2 7XH Guildford, Surrey (United Kingdom); Amouzad M, G. [University of Malaya, Faculty of Engineering, Department of Electrical Engineering, Integrated Lightwave Research Group, 50603 Kuala Lumpur (Malaysia); Addul R, H. A.; Mizanur R, A. K. M.; Zubair, H. T.; Begum, M.; Yusoff, Z.; Omar, N. Y. M. [Multimedia University, Faculty of Engineering, 2010 Cyberjaya, Selangor (Malaysia); Maah, M. J. [University of Malaya, Department of Chemistry, 50603 Kuala Lumpur (Malaysia); Collin, S. [National Physical Laboratory, Hampton Road, Teddington, TW11 OLW Middlesex (United Kingdom); Mat-Sharif, K. A.; Muhd-Yassin, S. Z.; Zulkifli, M. I., E-mail: d.a.bradley@surrey.ac.uk [Telekom Malaysia Research and Development Sdn Bhd., 63000 Cyberjaya, Selangor (Malaysia)

    2015-10-15

    Full text: Using tailor made sub-mm diameter doped-silica fibres, we are carrying out luminescence dosimetry studies for a range of situations, including thermoluminescence (Tl)investigations on a liquid alpha source formed of {sup 223}RaCl (the basis of the Bayer Health care product Xofigo), the Tl response to a 62 MeV proton source and Tl response to irradiation from an {sup 241}Am-Be neutron source. In regard to the former, in accord with the intrinsic high linear energy transfer (Let) and short path length (<100 um) of the α-particles in calcified tissue, the product is in part intended as a bone-seeking radionuclide for treatment of metastatic cancer, offering high specificity and efficacy. The Tl yield of Ge-doped SiO{sub 2} fibres has been investigated including for photonic crystal fibre un collapsed, flat fibres and single mode fibres, these systems offering many advantages over conventional passive dosimetry types. In particular, one can mention comparable and even superior sensitivity, an effective atomic number Z{sub eff} of the silica dosimetric material close to that of bone, and the glassy nature of the fibres offering the additional advantage of being able to place such dosimeters directly into liquid environments. Finally we review the use of our tailor made fibres for on-line radioluminescence measurements of radiotherapy beams. The outcome from these various lines of research is expected to inform development of doped fiber radiation dosimeters of versatile utility, ranging from clinical applications through to industrial studies and environmental evaluations. (Author)

  11. Personal Dosimetry Enhancement for Underground Workplaces

    Directory of Open Access Journals (Sweden)

    L. Thinová

    2005-01-01

    Full Text Available Personal dosimetry for underground workers mainly concerns measurement of the concentration of radon (and its daughters and the correct application of the data in dose calculation, using a biokinetic model for lung dosimetry. A conservative approach for estimating the potential dose in caves (or underground is based on solid state alpha track detector measurements. The obtained dataset is converted into an annual effective dose in agreement with the ICRP recommendations using the “cave factor”, the value of which depends on the spectrum of aerosol particles, or on the proportional representation of the unattached and the attached fraction and on the equilibrium factor. The main difference between apartments and caves is the absence of aerosol sources, high humidity, low ventilation rate and the uneven surface in caves. A more precisely determined dose value would have a significant impact on radon remedies or on restricting the time workers stay underground. In order to determine  how the effective dose is calculated, it is necessary to divide these areas into distinct categories by the following measuring procedures: continual radon measurement (to capture the differences in EERC between working hours and night-time, and also between daily and seasonal radon concentration variations; regular measurements of radon and its daughters to estimate the equilibrium factor and the presence of 218Po; regular indoor air flow measurements to study the location of the radon supply and its transfer among individual areas of the cave; natural radioactive element content evaluation in subsoils and in water inside/outside, a study of the radon sources in the cave; aerosol particle-size spectrum measurements to determine the free fraction; monitoring the behaviour of guides and workers to record the actual time spent in the cave, in relation to the continuously monitored levels of Rn concentration. 

  12. On flattening filter-free portal dosimetry.

    Science.gov (United States)

    Pardo, Eduardo; Castro Novais, Juan; Molina López, María Yolanda; Ruiz Maqueda, Sheila

    2016-01-01

    Varian introduced (in 2010) the option of removing the flattening filter (FF) in their C-Arm linacs for intensity-modulated treatments. This mode, called flattening filter-free (FFF), offers the advantage of a greater dose rate. Varian's "Portal Dosimetry" is an electronic portal imager device (EPID)-based tool for IMRT verification. This tool lacks the capability of verifying flattening filter-free (FFF) modes due to saturation and lack of an image prediction algorithm. (Note: the latest versions of this software and EPID correct these issues.) The objective of the present study is to research the feasibility of said verifications (with the older versions of the software and EPID). By placing the EPID at a greater distance, the images can be acquired without saturation, yielding a linearity similar to the flattened mode. For the image prediction, a method was optimized based on the clinically used algorithm (analytical anisotropic algorithm (AAA)) over a homogeneous phantom. The depth inside the phantom and its electronic density were tailored. An application was developed to allow the conversion of a dose plane (in DICOM format) to Varian's custom format for Portal Dosimetry. The proposed method was used for the verification of test and clinical fields for the three qualities used in our institution for IMRT: 6X, 6FFF and 10FFF. The method developed yielded a positive verification (more than 95% of the points pass a 2%/2 mm gamma) for both the clinical and test fields. This method was also capable of "predicting" static and wedged fields. A workflow for the verification of FFF fields was developed. This method relies on the clinical algorithm used for dose calculation and is able to verify the FFF modes, as well as being useful for machine quality assurance. The procedure described does not require new hardware. This method could be used as a verification of Varian's Portal Dose Image Prediction. PMID:27455487

  13. Dosimetry of low-energy beta radiation

    Energy Technology Data Exchange (ETDEWEB)

    Borg, J.

    1996-08-01

    Useful techniques and procedures for determination of absorbed doses from exposure in a low-energy {beta} radiation field were studied and evaluated in this project. The four different techniques included were {beta} spectrometry, extrapolation chamber dosimetry, Monte Carlo (MC) calculations, and exoelectron dosimetry. As a typical low-energy {beta} radiation field a moderated spectrum from a {sup 14}C source (E{sub {beta}},{sub max} =156 keV) was chosen for the study. The measured response of a Si(Li) detector to photons (bremsstrahlung) showed fine agreement with the MC calculated photon response, whereas the difference between measured and MC calculated responses to electrons indicates an additional dead layer thickness of about 12 {mu}m in the Si(Li) detector. The depth-dose profiles measured with extrapolation chambers at two laboratories agreed very well, and it was confirmed that the fitting procedure previously reported for {sup 147}Pm depth-dose profiles is also suitable for {beta} radiation from {sup 14}C. An increasing difference between measured and MC calculated dose rates for increasing absorber thickness was found, which is explained by limitations of the EGS4 code for transport of very low-energy electrons (below 10-20 keV). Finally a study of the thermally stimulated exoelectron emission (TSEE) response of BeO thin film dosemeters to {beta} radiation for radiation fields with maximum {beta} energies ranging from 67 keV to 2.27 MeV is reported. For maximum {beta} energies below approximately 500 keV, a decrease in the response amounting to about 20% was observed. It is thus concluded that a {beta} dose higher than about 10 {mu}Gy can be measured with these dosemeters to within 0 to -20% independently of the {beta}energy for E{sub {beta}},{sub max} values down to 67 keV. (au) 12 tabs., 38 ills., 71 refs.

  14. Biological dosimetry for astronauts: a real challenge.

    Science.gov (United States)

    Testard, I; Sabatier, L

    1999-12-01

    Manned space missions recently increased in number and duration, thus it became important to estimate the biological risks encountered by astronauts. They are exposed to cosmic and galactic rays, a complex mixture of different radiations. In addition to the measurements realized by physical dosimeters, it becomes essential to estimate real biologically effective doses and compare them to physical doses. Biological dosimetry of radiation exposures has been widely performed using cytogenetic analysis of chromosomes. This approach has been used for many years in order to estimate absorbed doses in accidental or chronic overexposures of humans. In addition to conventional techniques (Giemsa or FPG staining, R- or G-banding), faster and accurate means of analysis have been developed (fluorescence in situ hybridization [FISH] painting). As results accumulate, it appears that strong interindividual variability exists in the basal level of aberrations. Moreover, some aberrations such as translocations exhibit a high background level. Radiation exposures seem to induce variability between individual responses. Its extent strongly differs with the mode of exposure, the doses delivered, the kind of radiation, and the cytogenetic method used. This paper aims to review the factors that may influence the reliability of cytogenetic dosimetry. The emphasis is on the exposure to high linear energy transfer (LET) particles in space as recent studies demonstrated interindividual variations in doses estimated from aberration analysis after long-term space missions. In addition to the problem of dose estimates, the heterogeneity of cosmic radiation raises questions relating to the real numbers of damaged cells in an individual, and potential long-term risks. Actually, densely ionizing particles are extremely potent to induce late chromosomal instability, and again, interindividual variability exists in the expression of damage. PMID:10631347

  15. High sensitive radiation detector for radiology dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Valente, M.; Malano, F. [Instituto de Fisica Enrique Gaviola, Oficina 102 FaMAF - UNC, Av. Luis Medina Allende, Ciudad Universitaria, 5000 Cordoba (Argentina); Molina, W.; Vedelago, J., E-mail: valente@famac.unc.edu.ar [Laboratorio de Investigaciones e Instrumentacion en Fisica Aplicada a la Medicina e Imagenes por Rayos X, Laboratorio 448 FaMAF - UNC, Ciudad Universitaria, 5000 Cordoba (Argentina)

    2014-08-15

    Fricke solution has a wide range of applications as radiation detector and dosimetry. It is particularly appreciated in terms of relevant comparative advantages, like tissue equivalence when prepared in aqueous media like gel matrix, continuous mapping capability, dose rate recorded and incident direction independence as well as linear dose response. This work presents the development and characterization of a novel Fricke gel system, based on modified chemical compositions making possible its application in clinical radiology. Properties of standard Fricke gel dosimeter for high dose levels are used as starting point and suitable chemical modifications are introduced and carefully investigated in order to attain high resolution for low dose ranges, like those corresponding to radiology interventions. The developed Fricke gel radiation dosimeter system achieves the expected typical dose dependency, actually showing linear response in the dose range from 20 up to 4000 mGy. Systematic investigations including several chemical compositions are carried out in order to obtain a good enough dosimeter response for low dose levels. A suitable composition among those studied is selected as a good candidate for low dose level radiation dosimetry consisting on a modified Fricke solution fixed to a gel matrix containing benzoic acid along with sulfuric acid, ferrous sulfate, xylenol orange and ultra-pure reactive grade water. Dosimeter samples are prepared in standard vials for its in phantom irradiation and further characterization by spectrophotometry measuring visible light transmission and absorbance before and after irradiation. Samples are irradiated by typical kV X-ray tubes and calibrated Farmer type ionization chamber is used as reference to measure dose rates inside phantoms in at vials locations. Once sensitive material composition is already optimized, dose-response curves show significant improvement regarding overall sensitivity for low dose levels. According to

  16. Acute pancreatitis

    Directory of Open Access Journals (Sweden)

    Bo-Guang Fan

    2010-01-01

    Full Text Available Background : Acute pancreatitis continues to be a serious illness, and the patients with acute pancreatitis are at risk to develop different complications from ongoing pancreatic inflammation. Aims : The present review is to highlight the classification, treatment and prognosis of acute pancreatitis. Material & Methods : We reviewed the English-language literature (Medline addressing pancreatitis. Results : Acute pancreatitis is frequently caused by gallstone disease or excess alcohol ingestion. There are a number of important issues regarding clinical highlights in the classification, treatment and prognosis of acute pancreatitis, and treatment options for complications of acute pancreatitis including pancreatic pseudocysts. Conclusions : Multidisciplinary approach should be used for the management of the patient with acute pancreatitis.

  17. Acute pancreatitis

    Directory of Open Access Journals (Sweden)

    Bo-Guang Fan

    2010-05-01

    Full Text Available Background: Acute pancreatitis continues to be a serious illness, and the patients with acute pancreatitis are at risk to develop different complications from ongoing pancreatic inflammation. Aims: The present review is to highlight the classification, treatment and prognosis of acute pancreatitis. Material & Methods: We reviewed the English-language literature (Medline addressing pancreatitis. Results: Acute pancreatitis is frequently caused by gallstone disease or excess alcohol ingestion. There are a number of important issues regarding clinical highlights in the classification, treatment and prognosis of acute pancreatitis, and treatment options for complications of acute pancreatitis including pancreatic pseudocysts. Conclusions: Multidisciplinary approach should be used for the management of the patient with acute pancreatitis.

  18. Using Network Dynamical Influence to Drive Consensus

    Science.gov (United States)

    Punzo, Giuliano; Young, George F.; MacDonald, Malcolm; Leonard, Naomi E.

    2016-05-01

    Consensus and decision-making are often analysed in the context of networks, with many studies focusing attention on ranking the nodes of a network depending on their relative importance to information routing. Dynamical influence ranks the nodes with respect to their ability to influence the evolution of the associated network dynamical system. In this study it is shown that dynamical influence not only ranks the nodes, but also provides a naturally optimised distribution of effort to steer a network from one state to another. An example is provided where the “steering” refers to the physical change in velocity of self-propelled agents interacting through a network. Distinct from other works on this subject, this study looks at directed and hence more general graphs. The findings are presented with a theoretical angle, without targeting particular applications or networked systems; however, the framework and results offer parallels with biological flocks and swarms and opportunities for design of technological networks.

  19. Consensus document on European brain research

    DEFF Research Database (Denmark)

    Di Luca, Monica; Baker, Mary; Corradetti, Renato;

    2011-01-01

    the economic and social challenge posed by management of brain diseases in European countries. To setup a platform for discussion, EBC published in 2006 a Consensus Document on European Brain Research, describing needs and achievements of research in Europe and presenting proposals for future research...... programs. Since 2006, European research in neuroscience has advanced tremendously. The present document represents an update elaborated to reflect changes in research priorities and advances in brain research that have taken place since 2006. The same approach and format have been used here as in the......Psychiatric and neurological diseases combined represent a considerable social and economic burden in Europe. A recent study conducted by the European Brain Council (EBC) quantified the 'cost and burden' of major brain diseases in Europe, amounting to €386bn per year. Considering that these costs...

  20. Distributed Consensus with Finite Message Passing

    CERN Document Server

    Dash, Debashis

    2010-01-01

    Inspired by distributed resource allocation problems in dynamic topology networks, we initiate the study of distributed consensus with finite messaging passing. We first find a sufficient condition on the network graph for which no distributed protocol can guarantee a conflict-free allocation after $R$ rounds of message passing. Secondly we fully characterize the conflict minimizing zero-round protocol for path graphs, namely random allocation, which partitions the graph into small conflict groups. Thirdly, we enumerate all one-round protocols for path graphs and show that the best one further partitions each of the smaller groups. Finally, we show that the number of conflicts decrease to zero as the number of available resources increase.

  1. The consensus molecular subtypes of colorectal cancer.

    Science.gov (United States)

    Guinney, Justin; Dienstmann, Rodrigo; Wang, Xin; de Reyniès, Aurélien; Schlicker, Andreas; Soneson, Charlotte; Marisa, Laetitia; Roepman, Paul; Nyamundanda, Gift; Angelino, Paolo; Bot, Brian M; Morris, Jeffrey S; Simon, Iris M; Gerster, Sarah; Fessler, Evelyn; De Sousa E Melo, Felipe; Missiaglia, Edoardo; Ramay, Hena; Barras, David; Homicsko, Krisztian; Maru, Dipen; Manyam, Ganiraju C; Broom, Bradley; Boige, Valerie; Perez-Villamil, Beatriz; Laderas, Ted; Salazar, Ramon; Gray, Joe W; Hanahan, Douglas; Tabernero, Josep; Bernards, Rene; Friend, Stephen H; Laurent-Puig, Pierre; Medema, Jan Paul; Sadanandam, Anguraj; Wessels, Lodewyk; Delorenzi, Mauro; Kopetz, Scott; Vermeulen, Louis; Tejpar, Sabine

    2015-11-01

    Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression-based CRC classifications and facilitate clinical translation, we formed an international consortium dedicated to large-scale data sharing and analytics across expert groups. We show marked interconnectivity between six independent classification systems coalescing into four consensus molecular subtypes (CMSs) with distinguishing features: CMS1 (microsatellite instability immune, 14%), hypermutated, microsatellite unstable and strong immune activation; CMS2 (canonical, 37%), epithelial, marked WNT and MYC signaling activation; CMS3 (metabolic, 13%), epithelial and evident metabolic dysregulation; and CMS4 (mesenchymal, 23%), prominent transforming growth factor-β activation, stromal invasion and angiogenesis. Samples with mixed features (13%) possibly represent a transition phenotype or intratumoral heterogeneity. We consider the CMS groups the most robust classification system currently available for CRC-with clear biological interpretability-and the basis for future clinical stratification and subtype-based targeted interventions.

  2. Child abuser stereotypes: consensus among clinicians.

    Science.gov (United States)

    Krowchuk, H V

    1989-02-01

    This article reports the results of an investigation of nurses' stereotypes of child abusers. Ninety-four registered nurses completed a questionnaire that measured subjects' knowledge of child abuse; professional contact with perpetrators and victims of abuse; knowledge of the causes of child abuse; and child abuser stereotypes. Results reveal a consensus among the subjects as to the stereotypes associated with child abusers. This study supports the notion that nurses stereotype individuals on the basis of demographic characteristics. This study also raises questions regarding the bias that may result from the use of child abuser stereotypes. Clinical decision-making processes could become compromised if biased judgements are used in planning nursing care for clients diagnosed as child abusers. PMID:2930179

  3. Robust point matching via vector field consensus.

    Science.gov (United States)

    Jiayi Ma; Ji Zhao; Jinwen Tian; Yuille, Alan L; Zhuowen Tu

    2014-04-01

    In this paper, we propose an efficient algorithm, called vector field consensus, for establishing robust point correspondences between two sets of points. Our algorithm starts by creating a set of putative correspondences which can contain a very large number of false correspondences, or outliers, in addition to a limited number of true correspondences (inliers). Next, we solve for correspondence by interpolating a vector field between the two point sets, which involves estimating a consensus of inlier points whose matching follows a nonparametric geometrical constraint. We formulate this a maximum a posteriori (MAP) estimation of a Bayesian model with hidden/latent variables indicating whether matches in the putative set are outliers or inliers. We impose nonparametric geometrical constraints on the correspondence, as a prior distribution, using Tikhonov regularizers in a reproducing kernel Hilbert space. MAP estimation is performed by the EM algorithm which by also estimating the variance of the prior model (initialized to a large value) is able to obtain good estimates very quickly (e.g., avoiding many of the local minima inherent in this formulation). We illustrate this method on data sets in 2D and 3D and demonstrate that it is robust to a very large number of outliers (even up to 90%). We also show that in the special case where there is an underlying parametric geometrical model (e.g., the epipolar line constraint) that we obtain better results than standard alternatives like RANSAC if a large number of outliers are present. This suggests a two-stage strategy, where we use our nonparametric model to reduce the size of the putative set and then apply a parametric variant of our approach to estimate the geometric parameters. Our algorithm is computationally efficient and we provide code for others to use it. In addition, our approach is general and can be applied to other problems, such as learning with a badly corrupted training data set. PMID:24808341

  4. Individual dosimetry of workers and patients: implementation and perspectives; La dosimetrie individuelle des travailleurs et de patients: mise en oeuvre et perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Rannou, A.; Aubert, B.; Lahaye, Th.; Scaff, P.; Casanova, Ph.; Van Bladel, L.; Queinnec, F.; Valendru, N.; Jehanno, J.; Grude, E.; Berard, Ph.; Desbree, A.; Kafrouni, H.; Paquet, F.; Vanhavere, F.; Bridier, A.; Ginestet, Ch.; Magne, S.; Donadille, L.; Bordy, J.M.; Bottollier-Depois, J.F.; Barrere, J.L.; Ferragut, A.; Metivier, H.; Gaillard-Lecanu, E

    2008-07-01

    These days organised by the section of the technical protection of the S.F.R.P. review the different techniques of dosimetry used in France and Europe, and present the future orientations.The different interventions are as follow: Individual exposures of the workers: historic assessment and perspectives; medical exposure: where are the doses; legal obligations in individual dosimetry: which are the objective and the need on the subject; the dosimetry follow-up of workers by the S.I.S.E.R.I. system: assessment and perspectives; impact of the norm ISO 20553 on the follow-up of internal exposure; the implementation of the patient dose measurement in Belgium; techniques of passive dosimetry used in Europe; Supervision radiation protection at EDF: long term and short term approach; Comparison active and passive dosimetry at Melox; methodology for the choice of new neutron dosemeters; the working group M.E.D.O.R.: guide of internal dosimetry for the use of practitioners; O.E.D.I.P.E.: tool of modeling for the personalized internal dosimetry; the use of the Monte-Carlo method for the planning of the cancer treatment by radiotherapy becomes a reality; the works of the committee 2 of the ICRP; passive dosimetry versus operational dosimetry: situation in Europe; Implementation of the in vivo dosimetry in a radiotherapy department: experience of the Gustave Roussy institute; experience feedback on the in vivo measures in radiotherapy, based on the use of O.S.L. pellets; multi points O.S.L. instrumentation for the radiation dose monitoring in radiotherapy; dosimetry for extremities for medical applications: principle results of the European contract C.O.N.R.A.D.; references and perspectives in dosimetry; what perspectives for numerical dosimetry, an example: Sievert; system of dose management: how to answer to needs; the last technical evolutions in terms of electronic dosimetry in nuclear power plant; the fourth generation type reactors: what dosimetry. (N.C.)

  5. Review of the near-earth space radiation dosimetry

    Science.gov (United States)

    Guo, Jianming; Chen, Xiaoqian; Li, Shiyou

    2016-07-01

    The near-earth space radiation environment has a great effect to the spacecraft and maybe do harm to the astronaut's health. Thus, how to measure the radiation has become a serious challenge. In order to provide sufficient protection both for astronauts and for instruments on-board, dose equivalent and linear energy transfer should be measured instead of merely measuring total radiation dose. This paper reviews the methods of radiation measurement and presents a brief introduction of dosimetry instruments. The method can be divided into two different kinds, i.e., positive dosimetry and passive dosimetry. The former usually includes electronic devices which can be used for data storage and can offer simultaneous monitoring on space radiation. The passive dosimetry has a much simple structure, and need extra operation after on-orbit missions for measuring. To get more reliable data of radiation dosimetry, various instruments and methods had been applied in the spacecrafts and the manned spacecrafts in particular. The outlook of the development in the space radiation dosimetry measurement is also presented.

  6. Personnel neutron dosimetry using electrochemically etched CR-39 foils

    International Nuclear Information System (INIS)

    A personnel neutron dosimetry system has been developed based on the electrochemical etching of CR-39 plastic at elevated temperatures. The doses obtained using this dosimeter system are more accurate than those obtained using other dosimetry systems, especially when varied neutron spectra are encountered. This Cr-39 dosimetry system does not have the severe energy dependence that exists with albedo neutron dosimeters or the fading and reading problems encountered with NTA film. The dosimetry system employs an electrochemical etch procedure that be used to process large numbers of Cr-39 dosimeters. The etch procedure is suitable for operations where the number of personnel requires that many CR-39 dosimeters be processed. Experience shows that one full-time technician can etch and evaluate 2000 foils per month. The energy response to neutrons is fairly flat from about 80 keV to 3.5 MeV, but drops by about a factor of three in the 13 to 16 MeV range. The sensitivity of the dosimetry system is about 7 tracks/cm2/mrem, with a background equivalent to about 8 mrem for new CR-39 foils. The limit of sensitivity is approximately 10 mrem. The dosimeter has a significant variation in directional dependence, dropping to about 20% at 900. This dosimeter has been used for personnel neutron dosimetry at the Lawrence Livermore National Laboratory for more tha 18 months. 6 refs., 23 figs., 2 tabs

  7. Proceedings of the recent developments in radiation dosimetry

    International Nuclear Information System (INIS)

    Whilst 'Dosimetry' in its original sense deals with methods for a quantitative determination of energy deposited in a given medium by directly or indirectly ionizing radiations, the term is better known as a scientific sub-specialty in the fields of health physics and medical physics, where it is the calculation and assessment of the radiation dose received by the human body. Dosimetry is used extensively for radiation protection and is routinely applied to ensure radiological safety of occupational radiation workers. Internal dosimetry due to the ingestion or inhalation of radioactive materials relies on a variety of physiological or imaging techniques. External dosimetry, due to irradiation from an external source is based on measurements with a dosimeter, or inferred from other radiological protection instruments. Radiation dosimetry is one of the important research areas of Department of Atomic Energy (DAE). This research work is centered on the facilities such as nuclear reactors, reprocessing plants, high energy accelerators (research/industry/medical), radiation standards, food processing, radiation technology development, etc. In each of these facilities, radiation field environment is different and the associated dosimetry concepts are different. Papers relevant to INIS are indexed separately

  8. IAEA supported national thermoluminescence dosimetry audit networks for radiotherapy dosimetry: Summary of the posters presented in session 12b

    International Nuclear Information System (INIS)

    The IAEA has supported its Member States over many years by providing thermoluminescence dosimetry (TLD) based quality assurance audits for radiotherapy dosimetry. Over recent years it has extended this role by encouraging, supporting and assisting the development of national audit programmes, building on the IAEA's experience of operating a TLD system.Whenever possible, the IAEA establishes links between the national programmes and the IAEA Dosimetry Laboratory. The IAEA disseminates its standardized TLD methodology and provides technical backup to national TLD networks, ensuring at the same time traceability to primary dosimetry standards. Several countries have established TLD programmes to audit radiotherapy beams in hospitals with assistance from the IAEA, and the paper presents an overview of the activities in Algeria, Argentina, Australia, Brazil, China, Colombia, Cuba, India, the Republic of Korea, the Philippines and Poland. (author)

  9. [ANMCO/SIMEU Consensus document: In-hospital management of patients presenting with chest pain].

    Science.gov (United States)

    Zuin, Guerrino; Parato, Vito Maurizio; Groff, Paolo; Gulizia, Michele Massimo; Di Lenarda, Andrea; Cassin, Matteo; Cibinel, Gian Alfonso; Del Pinto, Maurizio; Di Tano, Giuseppe; Nardi, Federico; Rossini, Roberta; Ruggieri, Maria Pia; Ruggiero, Enrico; Scotto Di Uccio, Fortunato; Valente, Serafina

    2016-06-01

    Chest pain is a common general practice presentation that requires careful diagnostic assessment because of its diverse and potentially serious causes. However, the evaluation of acute chest pain remains challenging, despite many new insights over the past two decades. The percentage of patients presenting to the emergency departments because of acute chest pain appears to be increasing. Nowadays, there are two essential chest pain-related issues: 1) the missed diagnoses of acute coronary syndromes with a poor short-term prognosis; 2) the increasing percentage of hospitalizations of low-risk cases.It is well known that hospitalization of a low-risk chest pain patient can lead to unnecessary tests and procedures, with an increasing trend of complications and burden of costs. Therefore, the significantly reduced financial resources of healthcare systems induce physicians and administrators to improve the efficiency of care protocols for patients with acute chest pain. Despite the efforts of the Scientific Societies in producing statements on this topic, in Italy there is still a significant difference between emergency physicians and cardiologists in managing patients with chest pain. For this reason, the aim of the present consensus document is double: first, to review the evidence-based efficacy and utility of various diagnostic tools, and, second, to delineate the critical pathways (describing key steps) that need to be implemented in order to standardize the management of chest pain patients, making a correct diagnosis and treatment as uniform as possible across the entire country. PMID:27311086

  10. 77 FR 24251 - Consensus Standards, Light-Sport Aircraft

    Science.gov (United States)

    2012-04-23

    ... Federal Aviation Administration Consensus Standards, Light-Sport Aircraft AGENCY: Federal Aviation... availability of three new and three revised consensus standards relating to the provisions of the Sport Pilot and Light-Sport Aircraft rule issued July 16, 2004, and effective September 1, 2004....

  11. 78 FR 35085 - Consensus Standards, Light-Sport Aircraft

    Science.gov (United States)

    2013-06-11

    ... Federal Aviation Administration Consensus Standards, Light-Sport Aircraft AGENCY: Federal Aviation... availability of one new and seven revised consensus standards relating to the provisions of the Sport Pilot and Light-Sport Aircraft rule issued July 16, 2004, and effective September 1, 2004. ASTM...

  12. A consensus on criteria for cure of acromegaly

    NARCIS (Netherlands)

    A. Giustina (Andrea); P. Chanson (Philippe); M.D. Bronstein; A. Klibanski; S.W.J. Lamberts (Steven); F.F. Casanueva; P. Trainer; E. Ghigo (Ezio); K.K.Y. Ho; S. Melmed (Shlomo)

    2010-01-01

    textabstractObjective: The Acromegaly Consensus Group met in April 2009 to revisit the guidelines on criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons and endocrinologists with extensive experience of treating acromegaly. Evidence/Consensus Process: Relevant

  13. The Decrits Consensus Algorithm: Decentralized Agreement without Proof of Work

    OpenAIRE

    Pfeiffer, Ryan

    2014-01-01

    Decrits is a cryptocurrency in development that makes use of a novel consensus algorithm that does not require proof-of-work. This paper describes how the Decrits Consensus Algorithm (DCA) is as trustless as a proof-of-work algorithm while offering superior transaction security at virtually no cost.

  14. Treatment of adrenocorticotropin-dependent cushing's syndrome: A consensus statement

    NARCIS (Netherlands)

    B.M.K. Biller; A. Grossman (Ashley Barry); P.M. Stewart; S. Melmed (Shlomo); X. Bertagna; J. Bertherat (Jerome); M. Buchfelder; A. Colao (Annamaria); A.R. Hermus (Ad); L.J. Hofland (Leo); A. Klibanski; A. Lacroix; J.R. Lindsay; J. Newell-Price; L.K. Nieman; S. Petersenn; N. Sonino; G.K. Stalla (Günter); B. Swearingen; M.L. Vance; J.A.H. Wass (John); M. Boscaro

    2008-01-01

    textabstractObjective: Our objective was to evaluate the published literature and reach a consensus on the treatment of patients with ACTH-dependent Cushing's syndrome, because there is no recent consensus on the management of this rare disorder. Participants: Thirty-two leading endocrinologists, cl

  15. Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.

    NARCIS (Netherlands)

    Grossman, A.B.; Stewart, P.M.; Melmed, S.; Bertagna, X.; Bertherat, J.; Buchfelder, M.; Colao, A.; Hermus, A.R.M.M.; Hofland, L.J.; Klibanski, A.; Lacroix, A.; Lindsay, J.R.; Newell-Price, J.; Nieman, L.K.; Petersenn, S.; Sonino, N.; Stalla, G.K.; Swearingen, B.; Vance, M.L.; Wass, J.A.; Boscaro, M.

    2008-01-01

    OBJECTIVE: Our objective was to evaluate the published literature and reach a consensus on the treatment of patients with ACTH-dependent Cushing's syndrome, because there is no recent consensus on the management of this rare disorder. PARTICIPANTS: Thirty-two leading endocrinologists, clinicians, an

  16. Consensus in Directed Networks of Agents With Nonlinear Dynamics

    NARCIS (Netherlands)

    Yu, Wenwu; Chen, Guanrong; Cao, Ming; Qu, Z.

    2011-01-01

    This technical note studies the consensus problem for cooperative agents with nonlinear dynamics in a directed network. Both local and global consensus are defined and investigated. Techniques for studying the synchronization in such complex networks are exploited to establish various sufficient con

  17. Consensus Formation in Science Modeled by Aggregated Bibliographic Coupling

    DEFF Research Database (Denmark)

    Nicolaisen, Jeppe; Frandsen, Tove Faber

    2012-01-01

    journal as their unit of analysis. To produce a more fine grained citation analysis one needs to study consensus formation on an even more detailed level – i.e. the scientific document or article. To do so, we have developed a new technique that measures consensus by aggregated bibliographic couplings...

  18. Consensus of Multiagent Systems with Sampled Information and Noisy Measurements

    Directory of Open Access Journals (Sweden)

    Zhao-Jun Tang

    2013-01-01

    Full Text Available We consider consensus problems of first-order multiagent systems with sampled information and noisy measurements. A distributed stochastic approximation type algorithm is employed to attenuate the measurement noises. We provide conditions under which almost sure strong consensus is guaranteed for fixed and switching directed network topologies. Simulation results are provided to illustrate the theoretical results.

  19. The Consensus Definition Redefined from a Representational Perspective

    Science.gov (United States)

    Zand Scholten, Annemarie

    2012-01-01

    This paper presents the author's critique to Paul E. Newton's article titled "Clarifying the consensus definition of validity." In his article, Newton not only clarifies but also redefines the consensus definition of validity. In this redefinition he omits the term "construct" and introduces the term "measurement." Both omission and introduction…

  20. EDITORIAL: Special issue on radiation dosimetry Special issue on radiation dosimetry

    Science.gov (United States)

    Sharpe, Peter

    2009-04-01

    This special issue of Metrologia on radiation dosimetry is the second in a trilogy on the subject of ionizing radiation measurements, a field that is overseen by Sections I, II and III of the CIPM's Consultative Committee for Ionizing Radiation (CCRI). The work of Section II, on radionuclide metrology, was covered in issue 44(4), published in 2007, and that of Section III, on neutron metrology, will be covered in a special issue to be published shortly. This issue covers the work of Section I (x-rays and γ rays, and charged particles). The proposal to publish special issues of Metrologia covering the work of the CCRI Sections was first made in 2003 and refined at the two subsequent meetings of the CCRI in 2005 and 2007. The overall aim is to present the work of the CCRI to a wider metrological audience and to highlight the relevance and importance of the field. The main focus of our special issue on dosimetry metrology is on the 'state of the art' in the various areas covered, with an indication of the current developments taking place and the problems and challenges that remain. Where appropriate, this is set in a brief historical context, although it is not the aim to give a historical review. The need for accurate measurement has been appreciated from the pioneering days of the use of ionizing radiation in the early 20th century, particularly in the fields of diagnostic and therapeutic medicine. Over the years, the range of applications for ionizing radiation has expanded both in scope and in the types and energies of radiation employed. This has led to the need to develop a wide variety of measurement techniques and standards covering fields ranging from the low doses experienced in environmental and protection applications to the extremely high doses used in industrial processing. The different types of radiation employed give rise to the need for dose measurements in radiation beams whose effective penetration through a material such as water ranges from a

  1. Randomized Consensus Processing over Random Graphs: Independence and Convergence

    CERN Document Server

    Shi, Guodong

    2011-01-01

    Various consensus algorithms over random networks have been investigated in the literature. In this paper, we focus on the role that randomized individual decision-making plays to consensus seeking under stochastic communications. At each time step, each node will independently choose to follow the consensus algorithm, or to stick to current state by a simple Bernoulli trial with time-dependent success probabilities. This node decision strategy characterizes the random node-failures on a communication networks, or a biased opinion selection in the belief evolution over social networks. Connectivity-independent and arc-independent graphs are defined, respectively, to capture the fundamental nature of random network processes with regard to the convergence of the consensus algorithms. A series of sufficient and/or necessary conditions are given on the success probability sequence for the network to reach a global consensus with probability one under different stochastic connectivity assumptions, by which a comp...

  2. Joining consensus of networked multi-agent systems with nonlinear couplings and weighting constraints

    Science.gov (United States)

    Wang, Bohui; Wang, Jingcheng; Zhang, Langwen; Ge, Yang

    2016-04-01

    This paper studies the joining consensus of networked multi-agent systems subject to nonlinear couplings and weighted directed graphs via pinning control. A weighted-average consensus protocol is proposed to achieve the collective decision by interacting with the local information of some pinned agents. By proposing a novel joining consensus protocol, average consensus and general consensus strategies are joined to achieve an agreement for the weighting networked system. Furthermore, by calculating a proper consensus gain and using finite control Lyapunov controllers, an efficient joining consensus protocol is presented to improve the consensus speed. Sufficient conditions for achieving the consensuses asymptotically are proved. Finally, theoretical results are validated via simulations.

  3. Radiation protection dosimetry in medicine - Report of the working group n.9 of the European radiation dosimetry group (EURADOS) - coordinated network for radiation dosimetry (CONRAD - contract EC N) fp6-12684; Dosimetrie pour la radioprotection en milieu medical - rapport du groupe de travail n. 9 du European radiation dosimetry group (EURADOS) - coordinated netword for radiation dosimetry (CONRAD - contrat CE fp6-12684)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    This report present the results achieved within the frame of the work the WP 7 (Radiation Protection Dosimetry of Medical Staff) of the coordination action CONRAD (Coordinated Network for Radiation Dosimetry) funded through the 6. EU Framework Program. This action was coordinated by EURADOS (European Radiation Dosimetry Group). EURADOS is an organization founded in 1981 to advance the scientific understanding and the technical development of the dosimetry of ionising radiation in the fields of radiation protection, radiobiology, radiation therapy and medical diagnosis by promoting collaboration between European laboratories. WP7 coordinates and promotes European research for the assessment of occupational exposures to staff in therapeutic and diagnostic radiology workplaces. Research is coordinated through sub-groups covering three specific areas: 1. Extremity dosimetry in nuclear medicine and interventional radiology: this sub-group coordinates investigations in the specific fields of the hospitals and studies of doses to different parts of the hands, arms, legs and feet; 2. Practice of double dosimetry: this sub-group reviews and evaluates the different methods and algorithms for the use of dosemeters placed above and below lead aprons in large exposure during interventional radiology procedures, especially to determine effective doses to cardiologists during cardiac catheterization; and 3. Use of electronic personal dosemeters in interventional radiology: this sub-group coordinates investigations in laboratories and hospitals, and intercomparisons with passive dosemeters with the aim to enable the formulation of standards. (authors)

  4. A probabilistic gastrointestinal tract dosimetry model

    Science.gov (United States)

    Huh, Chulhaeng

    In internal dosimetry, the tissues of the gastrointestinal (GI) tract represent one of the most radiosensitive organs of the body with the hematopoietic bone marrow. Endoscopic ultrasound is a unique tool to acquire in-vivo data on GI tract wall thicknesses of sufficient resolution needed in radiation dosimetry studies. Through their different echo texture and intensity, five layers of differing echo patterns for superficial mucosa, deep mucosa, submucosa, muscularis propria and serosa exist within the walls of organs composing the alimentary tract. Thicknesses for stomach mucosa ranged from 620 +/- 150 mum to 1320 +/- 80 mum (total stomach wall thicknesses from 2.56 +/- 0.12 to 4.12 +/- 0.11 mm). Measurements made for the rectal images revealed rectal mucosal thicknesses from 150 +/- 90 mum to 670 +/- 110 mum (total rectal wall thicknesses from 2.01 +/- 0.06 to 3.35 +/- 0.46 mm). The mucosa thus accounted for 28 +/- 3% and 16 +/- 6% of the total thickness of the stomach and rectal wall, respectively. Radiation transport simulations were then performed using the Monte Carlo N-particle transport code (MCNP) 4C transport code to calculate S values (Gy/Bq-s) for penetrating and nonpenetrating radiations such as photons, beta particles, conversion electrons and auger electrons of selected nuclides, I123, I131, Tc 99m and Y90 under two source conditions: content and mucosa sources, respectively. The results of this study demonstrate generally good agreement with published data for the stomach mucosa wall. The rectal mucosa data are consistently higher than published data compared with the large intestine due to different radiosensitive cell thicknesses (350 mum vs. a range spanning from 149 mum to 729 mum) and different geometry when a rectal content source is considered. Generally, the ICRP models have been designed to predict the amount of radiation dose in the human body from a "typical" or "reference" individual in a given population. The study has been performed to

  5. SIXTH ERDA WORKSHOP ON PERSONNEL NEUTRON DOSIMETRY

    Energy Technology Data Exchange (ETDEWEB)

    Vallario, E. J.; Hankins, D. E.; Bramson, P. E.

    1977-07-11

    This workshop was the sixth of a series and was held on July 11 and 12, 1977, at the Oak Ridge National Laboratory in Oak Ridge, Tennessee. Those presenting papers at the Sixth Workshop prepared summary reports of their recent work for inclusion in this document. The reports are reproduced here as submitted by the participants, with only minor editing. This year's Workshop took a decidedly international flavor, with participants from seven countries in addition to the United States. The significance of this group's contributions has raised the possibility that the next Neutron Dosimetry Workshop may be held in Europe. Of particular interest at the Workshop was the keynote address by Dr. Harald Rossi. He commented that there is evidence that 1) accepted values of RBE for low absorbed doses of neutrons may be low by an order of magnitude or more and 2) the risk of leukemia is significant at 0.5 rad to the bone narrow. A reduction of the limit for permissible neutron exposure, which could result from consideration of this information, would necessitate major improvements in our "middle ages" neutron dosimetry. A number of participants reported conversions to thermoluminescent dosimeter (TLD) systems. This move has not been unanimous, however, as there were several reports of apparently satisfactory fission fragment, activation foil, and NTA film dosimeters. While thementionof NTA film resulted in the usual discussion of energy cut off and humidity effects, it seems the use of NTA in accelerator environments still has some merit. Discussion of fission fragment dosimeters centered around track etching techniques, which have shown some improvement. Of particular interest was Tommasino's report on the use of polycarbonate centrifuge tubes as the sensitive element. Thermally stimulated exoelectron emission (TSEE), never very popular for personnel dosimetry, has lost additional ground with the report that the neutron/gamma response ratio is much less than

  6. In vivo dosimetry with silicon diodes in total body irradiation

    International Nuclear Information System (INIS)

    The aim of this work is the characterization and application of silicon diode detectors for in vivo dosimetry in total body irradiation (TBI) treatments. It was evaluated the diode response with temperature, dose rate, gantry angulations and field size. A maximum response variation of 2.2% was obtained for temperature dependence. The response variation for dose rate and angular was within 1.2%. For field size dependence, the detector response increased with field until reach a saturation region, where no more primary radiation beam contributes for dose. The calibration was performed in a TBI setup. Different lateral thicknesses from one patient were simulated and then the calibration factors were determined by means of maximum depth dose readings. Subsequent to calibration, in vivo dosimetry measurements were performed. The response difference between diode readings and the prescribed dose for all treatments was below 4%. This difference is in agreement as recommended by the International Commission on Radiation Units and Measurements (ICRU), which is ±5%. The present work to test the applicability of a silicon diode dosimetry system for performing in vivo dose measurements in TBI techniques presented good results. These measurements demonstrated the value of diode dosimetry as a treatment verification method and its applicability as a part of a quality assurance program in TBI treatments. - Highlights: ► Characterization of a silicon diode dosimetry system. ► Application of the diodes for in vivo dosimetry in total body irradiation treatments. ► Implementation of in vivo dosimetry as a part of a quality assurance program in radiotherapy

  7. Twenty new ISO standards on dosimetry for radiation processing

    International Nuclear Information System (INIS)

    Twenty standards on essentially all aspects of dosimetry for radiation processing were published as new ISO standards in December 1998. The standards are based on 20 standard practices and guides developed over the past 14 years by Subcommittee E10.01 of the American Society for Testing and Materials (ASTM). The transformation to ISO standards using the 'fast track' process under ISO Technical Committee 85 (ISO/TC85) commenced in 1995 and resulted in some overlap of technical information between three of the new standards and the existing ISO Standard 11137 Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. Although the technical information in these four standards was consistent, compromise wording in the scopes of the three new ISO standards to establish precedence for use were adopted. Two of the new ISO standards are specifically for food irradiation applications, but the majority apply to all forms of gamma, X-ray, and electron beam radiation processing, including dosimetry for sterilization of health care products and the radiation processing of fruit, vegetables, meats, spices, processed foods, plastics, inks, medical wastes, and paper. Most of the standards provide exact procedures for using individual dosimetry systems or for characterizing various types of irradiation facilities, but one covers the selection and calibration of dosimetry systems, and another covers the treatment of uncertainties using the new ISO Type A and Type B evaluations. Unfortunately, nine of the 20 standards just adopted by the ISO are not the most recent versions of these standards and are therefore already out of date. To help solve this problem, efforts are being made to develop procedures to coordinate the ASTM and ISO development and revision processes for these and future ASTM-originating dosimetry standards. In the meantime, an additional four dosimetry standards have recently been published by the ASTM but have

  8. Cooling rate effects in thermoluminescence dosimetry grade lithium flouride. Implications for practical dosimetry.

    Science.gov (United States)

    Mason, E W; McKinlay, A F; Clark, I

    1976-01-01

    A systematic investigation of the effects of cooling rates in the range of 10(-1) to 2 X 10(5) degrees C min-1 applied to TLD-700, LiF thermoluminescence dosemeters has shown that the 'transfer sensitivity' effect observed by Booth, Johnson and Attix (1972) is only of importance for cooling rates greater than 10(3) degrees C min-1. Although it is concluded that for practical dosimetry purposes the effect may be ignored it is not clear why Booth et al. observed such large changes and until this discrepancy is explained it is recommended that a low temperature pre-irradiation anneal should be used.

  9. Review of radiation dosimetry research at the University of Wisconsin during 1961-1982

    International Nuclear Information System (INIS)

    The report provides a comprehensive review of the overall activities in this program since 1961. Research areas have included the development and use of lithium fluoride for thermoluminescent dosimetry, solid state neutron dosimetry, and ionization chamber research

  10. Permanent Breast Seed Implant Dosimetry Quality Assurance

    International Nuclear Information System (INIS)

    Purpose: A permanent breast seed implant is a novel method of accelerated partial breast irradiation for women with early-stage breast cancer. This article presents pre- and post-implant dosimetric data, relates these data to clinical outcomes, and makes recommendations for those interested in starting a program. Methods and Materials: A total of 95 consecutive patients were accrued into one of three clinical trials after breast-conserving surgery: a Phase I/II trial (67 patients with infiltrating ductal carcinoma); a Phase II registry trial (25 patients with infiltrating ductal carcinoma); or a multi-center Phase II trial for patients with ductal carcinoma in situ (3 patients). Contouring of the planning target volume (PTV) was done on a Pinnacle workstation and dosimetry calculations, including dose–volume histograms, were done using a Variseed planning computer. Results: The mean pre-implant PTV coverage for the V90, V100, V150, and V200 were as follows: 98.8% ± 1.2% (range, 94.5–100%); 97.3% ± 2.1% (range, 90.3–99.9%), 68.8% ± 14.3% (range, 32.7–91.5%); and 27.8% ± 8.6% (range, 15.1–62.3%). The effect of seed motion was characterized by post-implant dosimetry performed immediately after the implantation (same day) and at 2 months after the implantation. The mean V100 changed from 85.6% to 88.4% (p = 0.004) and the mean V200 changed from 36.2% to 48.3% (p 90 of approximately 100%, a V100 between 95% and 100%, and a V200 between 20% and 30%, as these numbers are associated with no local recurrences to date and good patient tolerance. In general, the target volume coverage improved over the duration of the seed therapy. The maximum skin dose, defined as the average dose over the hottest 1 × 1-cm2 surface area, should be limited to 90% of the prescription dose to minimize delayed skin toxicity.

  11. Biokinetics and dosimetry of inhaled tritiated aerosols

    Energy Technology Data Exchange (ETDEWEB)

    Trivedi, A. [Radiation Biology and Health Physics Branch, Atomic Energy of Canada Limited, Chalk River, Ontario (Canada); Cheng, Y.S. [Lovelace Respiratory Research Institute, Albuquerque, New Mexico (United States)

    2000-05-01

    Inhalation of tritiated pump oils and metal tritides is a potential radiological protection problem in some situations in tritium facilities. At present, the biokinetic data and validated dose models do not generally exist for chemical forms of tritium other than tritiated water and tritium gas. This situation calls for improving our radiobiological and dosimetric understanding for inhalation of tritiated aerosols. When tritiated pump oils or metal tritides were instilled into the lung, tritium was biotransformed to organically bound tritium (OBT) and tritiated water (HTO) in the body. The biokinetics of tritium-in-urine exhibited a sum of two exponential functions for OBT and HTO: short and long-term clearance components. For tritiated pump oils, 68% of the instilled activity was excreted in feces and less than 10% in urine. More than 90% of the applied activity was retained in the lung up to 5 d post-exposure, this declined to 40% and 5% of the instilled activity 7 d and 28 d post-exposure, respectively. No major long-term storage of OBT was observed in the body. For metal tritides (i.e., titanium tritide), 37% of instilled activity was eliminated via urine, 29% via feces, and 16% through exhaled air. The results on distribution and dynamics of tritium in the body were remarkably similar with our earlier studies on percutaneous absorption of tritiated pump oils or skin-contact exposure to tritium-gas-contaminated metal surfaces. Urinary excretion bioassay data from workers exposed to metal tritides or pump oils were analyzed using the MS-Windows 95 PC version of GENMOD{sup TM} internal dosimetry code. (GENMOD implements the ICRP Publication 66 respiratory tract model and compartment models rather than retention functions of tritium compounds as describes by ICRP Publication 67). The simulated tritium urinary excretion data for exposed workers indicated that Type S solubility classification is more appropriate that Type M default as prescribed ICRP Publication 66

  12. Consensus and Synchronization in Complex Networks

    CERN Document Server

    2013-01-01

    Synchronization in complex networks is one of the most captivating cooperative phenomena in nature and has been shown to be of fundamental importance in such varied circumstances as the continued existence of species, the functioning of heart pacemaker cells, epileptic seizures, neuronal firing in the feline visual cortex and cognitive tasks in humans. E.g. coupled visual and acoustic interactions make fireflies flash, crickets chirp, and an audience clap in unison. On the other hand, in distributed systems and networks, it is often necessary for some or all of the nodes to calculate some function of certain parameters, e.g. sink nodes in sensor networks being tasked with calculating the average measurement value of all the sensors or multi-agent systems in which all agents are required to coordinate their speed and direction. When all nodes calculate the same function of the initial values in the system, they are said to reach consensus. Such concepts - sometimes also called state agreement, rendezvous, and ...

  13. Consensus maps of cloned plant cuticle genes

    Institute of Scientific and Technical Information of China (English)

    Eviatar; Nevo

    2010-01-01

    Plant cuticle,which covers the plant surface,consists of waxes and cutins,and is associated with plant drought,cold,and salt resistance.Hitherto,at least 47 genes participating in the formation of plant cuticle have been cloned from Arabidopsis thaliana,Oryza sativa,Zea mays,Ricinus communis,Brassica napus,and Medicago truncatula;and about 85% of them encode proteins sharing above 50% identities with their rice homologous sequences.These cloned cuticle genes were mapped in silico on different chromosomes of rice and Arabidopsis,respectively.The mapping results revealed that plant cuticle genes were not evenly distributed in both genomes.About 40% of the mapped cuticle genes were located on chromosome 1 in Arabidopsis,while 20% of the mapped cuticle genes were located on chromosome 2 but none on chromosome 12 in rice.Some cloned plant cuticle genes have several rice homologous sequences,which might be produced by chromosomal segment duplication.The consensus map of cloned plant cuticle genes will provide important clues for the selection of candidate genes in a positional cloning of an unknown cuticle gene in plants.

  14. Skin tears: state of the science: consensus statements for the prevention, prediction, assessment, and treatment of skin tears©.

    Science.gov (United States)

    LeBlanc, Kimberly; Baranoski, Sharon

    2011-09-01

    The appropriate management of patients with skin tears is an ongoing challenge for healthcare professionals. Skins tears are often painful, acute wounds resulting from trauma to the skin and are largely preventable. Healthcare professionals must be able to identify individuals at risk for skin tears and aid in the prevention of these wounds and in their treatment when they occur. Despite preliminary studies that suggest skin tears may be more prevalent than pressure ulcers, there remains a paucity of literature to guide prevention, assessment, and treatment of skin tears. As a result, these wounds are often mismanaged and misdiagnosed, leading to complications, including pain, infection, and delayed wound healing. In addition, skin tears increase caregiver time and facility costs, cause anxiety for patients and families, and may reflect poorly on the quality of care delivered in a facility. In an effort to shift awareness toward this largely unheeded healthcare issue, a consensus panel of 13 internationally recognized key opinion leaders convened to establish consensus statements on the prevention, prediction, assessment, and treatment of skin tears. The initial consensus panel meeting was held in January 2011 and was made possible by an unrestricted educational grant from Hollister Wound Care. This document details the consensus definition and statements, as well as recommendations for future research and steps toward establishing a validated, comprehensive program for managing skin tears.

  15. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2007-03-12

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at Hanford. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with 10 CFR 835, DOELAP, DOE-RL, ORP, PNSO, and Hanford contractor requirements. The dosimetry system is operated by PNNL’s Hanford External Dosimetry Program (HEDP) which provides dosimetry services to all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee (HPDAC) which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. Rev. 0 marks the first revision to be released through PNNL’s Electronic Records & Information Capture Architecture (ERICA) database. Revision numbers that are whole numbers reflect major revisions typically involving changes to all chapters in the document. Revision numbers that include a decimal fraction reflect minor revisions, usually restricted to selected chapters or selected pages in the document. Revision Log: Rev. 0 (2/25/2005) Major revision and expansion. Rev. 0.1 (3/12/2007) Minor

  16. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2010-04-01

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  17. Hanford External Dosimetry Technical Basis Manual PNL-MA-842

    Energy Technology Data Exchange (ETDEWEB)

    Rathbone, Bruce A.

    2011-04-04

    The Hanford External Dosimetry Technical Basis Manual PNL-MA-842 documents the design and implementation of the external dosimetry system used at the U.S. Department of Energy (DOE) Hanford site. The manual describes the dosimeter design, processing protocols, dose calculation methodology, radiation fields encountered, dosimeter response characteristics, limitations of dosimeter design under field conditions, and makes recommendations for effective use of the dosimeters in the field. The manual describes the technical basis for the dosimetry system in a manner intended to help ensure defensibility of the dose of record at Hanford and to demonstrate compliance with requirements of 10 CFR 835, the DOE Laboratory Accreditation Program, the DOE Richland Operations Office, DOE Office of River Protection, DOE Pacific Northwest Office of Science, and Hanford’s DOE contractors. The dosimetry system is operated by the Pacific Northwest National Laboratory (PNNL) Hanford External Dosimetry Program which provides dosimetry services to PNNL and all Hanford contractors. The primary users of this manual are DOE and DOE contractors at Hanford using the dosimetry services of PNNL. Development and maintenance of this manual is funded directly by DOE and DOE contractors. Its contents have been reviewed and approved by DOE and DOE contractors at Hanford through the Hanford Personnel Dosimetry Advisory Committee which is chartered and chaired by DOE-RL and serves as means of coordinating dosimetry practices across contractors at Hanford. This manual was established in 1996. Since its inception, it has been revised many times and maintained by PNNL as a controlled document with controlled distribution. The first revision to be released through PNNL’s Electronic Records & Information Capture Architecture database was designated Revision 0. Revision numbers that are whole numbers reflect major revisions typically involving significant changes to all chapters in the document. Revision

  18. Risk factors and outcome of transfusion-related acute lung injury in the critically ill : A nested case-control study

    NARCIS (Netherlands)

    Vlaar, Alexander P. J.; Binnekade, Jan M.; Prins, David; van Stein, Danielle; Hofstra, Jorrit J.; Schultz, Marcus J.; Juffermans, Nicole P.

    2010-01-01

    Objectives: To determine the incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of critically ill patients. Design: In a retrospective cohort study, patients with transfusion-related acute lung injury were identified using the consensus criteria of acute lung i

  19. Optimized MR imaging for polyacrylamide gel dosimetry

    International Nuclear Information System (INIS)

    Polyacrylamide gels are a powerful tool to measure radiation dose by quantifying the NMR T2 relaxation times of the irradiated gel. The exploitation of these radiation sensitive gels in clinical radiotherapy requires accurate mapping of T2 values. This paper describes the optimization strategy used to identify accurate and practical methods of measuring the range of T2 values typical of gel dosimeters (140-700 ms). The MR imaging techniques used to measure T2 values and the choice of image acquisition parameters are described. Four sequences are compared and the results are analysed in terms of accuracy, signal-to-noise ratio and acquisition time. A multiple spin echo sequence was found to yield the most accurate results (98.9%). Single spin echo sequences, such as Hahn spin echo and EPI spin echo, were found to measure gel T2 values with an accuracy of 90.1%. This paper reports the importance of careful selection and optimization of the MR imaging sequences for accurate and reliable polyacrylamide gel dosimetry. (author)

  20. US Navy's personnel neutron dosimetry program

    International Nuclear Information System (INIS)

    Since 1964 the Navy has been monitoring personnel for exposure to neutrons. With nuclear reactors, special nuclear materials, neutron calibration sources, and high energy linear accelerators, the Navy has organize over more neutron sources than any other single organization in the world. Personnel neutron monitoring in the Navy was first accomplished using NTA film from 1964 through 1980. In 1975 the Navy instituted albedo neutron dosimetry, which would completely replace NTA film in 1981. From 1975 through 1982 the Navy directed considerable efforts toward assessing the complexity of its field neutron spectra, evaluating techniques to correct the neutron response of its albedo dosimeter, and developing methods to perform neutron area monitoring. As a result of investigating field neutron spectra, the Navy again modified its calibration procedure in September 1979, by changing its calibration source to Cf-252 moderated with two inches of polyethylene. This source's spectrum more closely represented spectra found aboard ships, and as a result, shipboard personnel neutron doses were reduced by 45%. The Navy's newest albedo dosimeter is calibrated on an ANSI standard PMMA phantom using a D(sub 2)O moderated Cf-252 source at 50 cm