WorldWideScience

Sample records for activity programme kiss

  1. 'Kiss, cuddle, squeeze': the experiences and meaning of touch among parents of children with autism attending a Touch Therapy Programme.

    Science.gov (United States)

    Cullen, Lesley; Barlow, Julie

    2002-09-01

    The aim of this qualitative study was to explore the experiences and meaning of touch between parents and children with autism before and after attending a Touch Therapy Programme. The sample comprised 12 parents (1 father and 11 mothers) of children (1 female and 11 male) with autism. Parents were interviewed before and immediately after the 8-week programme. Pre-programme results suggested that children were controlling the experience of touch. Parents felt 'hurt' in response to the 'aloof nature of autism, and natural parenting instincts (e.g. spontaneous cuddles) were restricted. Post-programme results suggested that children appeared to tolerate touch. Parents reported that routine tasks (e.g. dressing) were accomplished more easily and that children appeared generally more relaxed. Parents reported feeling 'closer' to their children and felt that the touch therapy had opened a communication channel between themselves and their children.

  2. ``Sweetening'' Technical Physics with Hershey's Kisses

    Science.gov (United States)

    Stone, Chuck

    2003-04-01

    This paper describes an activity in which students measure the mass of each candy in one full bag of Hershey's Kisses and then use a simple spreadsheet program to construct a histogram showing the number of candies as a function of mass. Student measurements indicate that one single bag of 80 Kisses yields enough data to produce a noticeable variation in the candy's mass distribution. The bimodal character of this distribution provides a useful discussion topic. This activity can be performed as a classroom project, a laboratory exercise, or an interactive lecture demonstration. In all these formats, students have the opportunity to collect, organize, process, and analyze real data. In addition to strengthening graphical analysis skills, this activity introduces students to fundamentals of statistics, manufacturing processes in the industrial workplace, and process control techniques.

  3. Kissing Nevus of the Penis.

    Science.gov (United States)

    Jiang, Shan; Chen, Yan; Hinchliffe, Taylor E; Wu, Tianfu; Stephen, Tyring

    2018-03-01

    Kissing nevus is a very rare congenital melanocytic nevus. Here, we describe one case of kissing nevus on the penis. A 15-year boy presented with asymptomatic black to dark brown color patches on his penis. Histopathological findings showed that there were nests and cords of nevus cells in upper dermis. No significant cytologic atypia and mitoses were noted. Immunohistochemical stains revealed a partial positive for HMB-45 only in upper dermis and a stronger positivity for S-100 in almost all nevus cells. We diagnosed the lesion as kissing nevus of penis. The patient and his parents refused further treatment, and the patient is being followed in our clinic.

  4. Developmental Profile and Sexually Dimorphic Expression of Kiss1 and Kiss1r in the Fetal Mouse Brain

    Directory of Open Access Journals (Sweden)

    John Gabriel Knoll

    2013-10-01

    Full Text Available The hypothalamic-pituitary-gonadal axis (HPG is a complex neuroendocrine circuit involving multiple levels of regulation. Kisspeptin neurons play essential roles in controlling the HPG axis from the perspectives of puberty onset, oscillations of gonadotropin releasing hormone (GnRH neuron activity and the pre-ovulatory LH surge. The current studies focus on the expression of kisspeptin during murine fetal development using in situ hybridization (ISH, quantitative reverse transcription real-time PCR (QPCR and immunocytochemistry. Expression of mRNA coding for kisspeptin (KISS1 and its receptor KISS1R was observed at embryonic (E day 13 by ISH. At E13 and other later ages examined, Kiss1 signal in individual cells within the arcuate nucleus (ARC appeared stronger in females than males. ISH examination of agonadal steroidogenic factor-1 (Sf1 knockout mice revealed that E17 XY knockouts resembled wild-type XX females. These findings raise the possibility that gonadal hormones modulate the expression of Kiss1 in the ARC prior to birth. The sex and genotype differences were tested quantitatively by QPCR experiments in dissected hypothalami from mice at E17 and adulthood. Females had significantly more Kiss1 than males at both ages, even though the number of cells detected by ISH was similar. In addition, QPCR revealed a significant difference in the amount of Kiss1 mRNA in Sf1 mice with wild-type (WT XY mice expressing less than XY knockouts (KO and XX mice of both genotypes. The detection of immunoreactive KISS1 in perikarya of the ARC at E17 indicates that early mRNA is translated to peptide. The functional significance of this early expression of Kiss1 awaits elucidation.

  5. IAEA activities in support of RERTR programme

    International Nuclear Information System (INIS)

    Akhtar, K.M.

    2004-01-01

    The International Atomic Energy Agency has supported the programme for Reduced Enrichment for Research and Test Reactors from the very initial stage. As part of its research reactor programme, the Agency has convened several technical meetings and seminars, issued many publications on the subject, and provided technical and financial assistance to many reactor operators in the developing countries. The worldwide current status of fuel enrichment for research reactors and a resume of Agency activities are presented in this paper. (author)

  6. Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cells.

    Science.gov (United States)

    Qiu, Xiaoliang; Dowling, Abigail R; Marino, Joseph S; Faulkner, Latrice D; Bryant, Benjamin; Brüning, Jens C; Elias, Carol F; Hill, Jennifer W

    2013-03-01

    Pubertal onset only occurs in a favorable, anabolic hormonal environment. The neuropeptide kisspeptin, encoded by the Kiss1 gene, modifies GnRH neuronal activity to initiate puberty and maintain fertility, but the factors that regulate Kiss1 neurons and permit pubertal maturation remain to be clarified. The anabolic factor insulin may signal nutritional status to these neurons. To determine whether insulin sensing plays an important role in Kiss1 neuron function, we generated mice lacking insulin receptors in Kiss1 neurons (IR(ΔKiss) mice). IR(ΔKiss) females showed a delay in vaginal opening and in first estrus, whereas IR(ΔKiss) males also exhibited late sexual maturation. Correspondingly, LH levels in IR(ΔKiss) mice were reduced in early puberty in both sexes. Adult reproductive capacity, body weight, fat composition, food intake, and glucose regulation were comparable between the 2 groups. These data suggest that impaired insulin sensing by Kiss1 neurons delays the initiation of puberty but does not affect adult fertility. These studies provide insight into the mechanisms regulating pubertal timing in anabolic states.

  7. Inspection of licensee - Maintenance programme and activities

    International Nuclear Information System (INIS)

    2013-01-01

    An effective maintenance programme is critical to sustained safe and reliable operation of nuclear power plants. The Working Group on Inspection Practices (WGIP) concluded that when a licensee has an effective maintenance programme, the overall operating safety of the plant is improved and the protection of public health and safety enhanced. All Regulatory Bodies (RB) consider maintenance to be an important area for oversight. Although a variety of inspection practices are being used; RB are actively monitoring licensee performance. Specifically the following conclusions were reached and commendable practices identified: - Maintenance oversight by regulators appears to be in a stable continuous improvement state. Most regulators are executing inspection oversight based on an existing regulatory framework. - The performance of a licensee's maintenance programme is recognized as important part of maintaining nuclear safety. The result of the maintenance program assessment is included in the overall performance assessment of a license. - Maintenance inspection activities are recognized as an important part of the regulatory oversight process. Inspection activities are based on the safety significance and nature of work being performed by the licensee. - The effectiveness of the maintenance inspection activities is recognized to rely on properly qualified inspectors; who are adequately supported by specialists. Training and qualification of inspectors should be based on how the RB reviews and inspects licensee maintenance programmes. - Reporting requirements are identified to provide information on the licensees maintenance programme, and to help guide inspection activities. - Performance Indicators are recognized as a useful tool for helping focus regulatory activities. Basic PI are identified and tracked by the RB, and use of PI by the licensee is monitored. - Inspections are designed to confirm that the licensee is planning and scheduling maintenance with due

  8. Present activities of the Danube environmental Programme

    International Nuclear Information System (INIS)

    Botterweg, T.; Turcan, J.

    1997-01-01

    The international character of the Danube river basin reflects among other aspects also the importance and the need of international co-operation at various levels. The response of this need has been expressed by the formation of different international commissions and organisations in the basin, covering mainly technical but in the recent time also the environmental interests of the riparian states. The Danube countries, several G-24 governments, as well as international and non governmental organisations decided in the autumn of 1991 to start the Environmental Programme for the Danube River Basin (EPDRB) and form the Danube Task Force. A joint Programme work plan was agreed by the Task Force in February 1992, thereby launching a series of priority projects designed to built environmental co-operation among the Danube countries. The main objective was to establish an operational basis for strategic and integrated management of the Danube river basin environment. The planning and working documents, which were outlining the activities within the EPDRB are the Strategic Action Plan (SAP-1994) and the Strategic Action Plan Implementation Programme (SIP-1996). These documents frame the works of the 13 Tasks of the Applied Research Programme, Sub-Groups of the Accident Emergency Warning System, Monitoring, Laboratories and Information Management and Data Management as well as the major areas of work, divided in Groups and Clusters, each of which will involve projects to be carried out in a number of Danube countries. All activities are oriented to the improvement of the environment, however special attention is paid to task dealing with biodiversity, wetlands restoration, water and soil protection. The main funding, which is secured until the year 2000 comes from the Danube countries, the EU Phare and Tacis programmes, the UN GEF, international banks and foundations. (author)

  9. Programmationactive en OCaml

    OpenAIRE

    Deleuze , Christophe

    2009-01-01

    15 pages; International audience; La programmationactive permet d'écrire des programmes sous forme d'un ensemble de processus qui s'exécutent de manière synchronisée et communiquent par diffusion de signaux. Ce paradigme peut être fourni par des langages spécialisés (parfois basés sur des langages “classiques”) ou par des bibliothèques. Le langage ReactiveML est un tel langage réactif basé sur OCaml. Nous décrivons ici une bibliothèque OCaml fournissant les construc- tions réactives de Rea...

  10. Redundancy in Kiss1 Expression Safeguards Reproduction in the Mouse

    Science.gov (United States)

    Popa, Simina M.; Moriyama, Ryutaro M.; Caligioni, Claudia S.; Yang, Jasmine J.; Cho, Caroline M.; Concepcion, Tessa L.; Oakley, Amy E.; Lee, In Hae; Sanz, Elisenda; Amieux, Paul S.; Caraty, Alain; Palmiter, Richard D.; Navarro, Victor M.; Chan, Yee-Ming; Seminara, Stephanie B.; Clifton, Donald K.

    2013-01-01

    Kisspeptin (Kiss1) signaling to GnRH neurons is widely acknowledged to be a prerequisite for puberty and reproduction. Animals lacking functional genes for either kisspeptin or its receptor exhibit low gonadotropin secretion and infertility. Paradoxically, a recent study reported that genetic ablation of nearly all Kiss1-expressing neurons (Kiss1 neurons) does not impair reproduction, arguing that neither Kiss1 neurons nor their products are essential for sexual maturation. We posited that only minute quantities of kisspeptin are sufficient to support reproduction. If this were the case, animals having dramatically reduced Kiss1 expression might retain fertility, testifying to the redundancy of Kiss1 neurons and their products. To test this hypothesis and to determine whether males and females differ in the required amount of kisspeptin needed for reproduction, we used a mouse (Kiss1-CreGFP) that has a severe reduction in Kiss1 expression. Mice that are heterozygous and homozygous for this allele (Kiss1Cre/+ and Kiss1Cre/Cre) have ∼50% and 95% reductions in Kiss1 transcript, respectively. We found that although male Kiss1Cre/Cre mice sire normal-sized litters, female Kiss1Cre/Cre mice exhibit significantly impaired fertility and ovulation. These observations suggest that males require only 5% of normal Kiss1 expression to be reproductively competent, whereas females require higher levels for reproductive success. PMID:23736293

  11. Never Been Kissed: Correlates of Lifetime Kissing Status in U.S. University Students.

    Science.gov (United States)

    Lefkowitz, Eva S; Wesche, Rose; Leavitt, Chelom E

    2018-05-01

    Kissing a partner occurs relatively early during adolescence. Thus, young adults who have never kissed are off-time from their peers. Substantial exploration in the areas of identity and intimacy occur during this period, and kissing may fulfill both of these functions, addressing autonomy and relatedness motives for sexual behaviors. We examined the prevalence and personal, contextual, and adjustment/health predictors of delayed onset of kissing. An ethnically and racially diverse sample of traditionally aged first year university students (N = 738; 50.7% female) completed online surveys. Only 14.2% of young adults had never kissed a partner on the lips. Compared to their peers who had kissed partners, young adults who had never kissed were more likely to be Asian-American, less likely to be in a romantic relationship, were less extraverted, were more likely to be in the Honors College, and drank alcohol less frequently. In bivariate models but not the multivariate model, young adults who had never kissed were more neurotic, had mothers who were less facilitating of independence, and had lower self-esteem. Findings inform understanding of normative sexuality development, and inform future research on normative and off-time sexual behaviors in young adulthood.

  12. Present status of the KISS project

    Science.gov (United States)

    Miyatake, H.; Wada, M.; Watanabe, X. Y.; Hirayama, Y.; Schury, P.; Ahmed, M.; Ishiyama, H.; Jeong, S. C.; Kakiguchi, Y.; Kimura, S.; Moon, J. Y.; Mukai, M.; Oyaizu, M.; Park, J. H.

    2018-04-01

    KISS project aims at finding an astrophysical condition for synthesizing r-process heavy element isotopes, which are characterized as the third peak in the solar abundance pattern. This is an experimental challenge in nuclear physics to measure ground and isomeric state properties of unknown nuclei around the region of N=126 isotones. So far we have constructed and developed new type of mass separation system, KISS (KEK Isotope Separation System) and performed measurements of lifetimes and hyperfine structures of some platinum and iridium neutron-rich radioactive isotopes by applying multi-nucleon transfer reactions and in-gas laser ionization and spectroscopy (IGLIS) methods. In this report, recent physics results, updated KISS performance, and future's research plan including a challenge of a systematic mass measurement with MRTOF (Multi-Reflection Time-Of-Flight mass spectrograph) are presented.

  13. Stated Uptake of Physical Activity Rewards Programmes Among Active and Insufficiently Active Full-Time Employees.

    Science.gov (United States)

    Ozdemir, Semra; Bilger, Marcel; Finkelstein, Eric A

    2017-10-01

    Employers are increasingly relying on rewards programmes in an effort to promote greater levels of activity among employees; however, if enrolment in these programmes is dominated by active employees, then they are unlikely to be a good use of resources. This study uses a stated-preference survey to better understand who participates in rewards-based physical activity programmes, and to quantify stated uptake by active and insufficiently active employees. The survey was fielded to a national sample of 950 full-time employees in Singapore between 2012 and 2013. Participants were asked to choose between hypothetical rewards programmes that varied along key dimensions and whether or not they would join their preferred programme if given the opportunity. A mixed logit model was used to analyse the data and estimate predicted uptake for specific programmes. We then simulated employer payments based on predictions for the percentage of each type of employee likely to meet the activity goal. Stated uptake ranged from 31 to 67% of employees, depending on programme features. For each programme, approximately two-thirds of those likely to enrol were insufficiently active. Results showed that insufficiently active employees, who represent the majority, are attracted to rewards-based physical activity programmes, and at approximately the same rate as active employees, even when enrolment fees are required. This suggests that a programme with generous rewards and a modest enrolment fee may have strong employee support and be within the range of what employers may be willing to spend.

  14. Examining the possible functions of kissing in romantic relationships.

    Science.gov (United States)

    Wlodarski, Rafael; Dunbar, Robin I M

    2013-11-01

    Recent research suggests that romantic kissing may be utilized in human sexual relationships to evaluate aspects of a potential mate's suitability, to mediate feelings of attachment between pair-bonded individuals, or to facilitate arousal and initiate sexual relations. This study explored these potential functions of romantic kissing by examining attitudes towards the importance of kissing in the context of various human mating situations. The study involved an international online questionnaire, which was completed by 308 male and 594 female participants aged 18-63 years. Support was found for the hypothesis that kissing serves a useful mate-assessment function: women, high mate-value participants, and participants high in sociosexual orientation placed greater importance on kissing in romantic relationships and stated that an initial kiss was more likely to affect their attraction to a potential mate than did men, low-mate value participants or low sociosexual orientation participants. Kissing also seemed to be utilized in the mediation of pair-bond attachments: kissing was seen to be more important at established stages of relationships by low sociosexual participants, kissing was generally seen as more important in long-term relationship contexts (but particularly so by women), and kissing frequency was found to be related to relationship satisfaction. The findings of this research showed very little evidence to support the hypothesis that the primary function of kissing is to elevate levels of arousal.

  15. What's in a Kiss? The Effect of Romantic Kissing on Mate Desirability

    Directory of Open Access Journals (Sweden)

    Rafael Wlodarski

    2014-01-01

    Full Text Available Past research suggests that various courtship rituals, such as romantic kissing, may convey useful mate quality information. Two studies were carried out to examine how purported romantic kissing abilities, as a potential cue to some form of mate information, affect appraisals of potential mating partners. In Experiment 1, 724 participants were presented with vignette descriptions of potential mating partners and were asked to rate partner desirability for various mating-related situations. The primary result of this experiment was that purported kissing ability increased mate desirability in “casual sex” mating situations for women to a greater extent than for men. Experiment 2 repeated the same procedure with another 178 participants, this time including visual information alongside vignette descriptions containing kissing-related information to examine the relative effects of these two modalities. It was found that the presence of a picture alongside a descriptive vignette negated the effect of kissing-related information only when rating potential partners on attractiveness or desirability for further courtship, though not when evaluating partners for casual sex or long-term relationship scenarios. Visual information containing “attractive” photos of potential partners was also found to have a greater effect on men's ratings of partner desirability than on women's ratings of partner desirability. The results are discussed in light of romantic kissing's potential function of conveying important mate quality and desirability information, and its relative role in the presence of additional visual mate cues.

  16. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters

    DEFF Research Database (Denmark)

    Ansel, L; Bolborea, M; Bentsen, A H

    2010-01-01

    In seasonal breeders, reproduction is synchronized to seasons by day length via the pineal hormone melatonin. Recently, we have demonstrated that Kiss1, a key activator of the reproductive function, is down-regulated in sexually inactive hamsters maintained in inhibitory short days (SDs). In rode......In seasonal breeders, reproduction is synchronized to seasons by day length via the pineal hormone melatonin. Recently, we have demonstrated that Kiss1, a key activator of the reproductive function, is down-regulated in sexually inactive hamsters maintained in inhibitory short days (SDs......). In rodents, Kiss1 is expressed in the anteroventral periventricular nucleus (AVPV) and in the arcuate nucleus (ARC). Because both the duration of the nocturnal peak of melatonin and circulating sex steroid levels vary with photoperiod, the aim of this study was to determine whether melatonin and sex steroids...... differentially regulate Kiss1 expression in the ARC and the AVPV. Kiss1 expression was examined by in situ hybridization in both male and female hamsters kept in various experimental conditions, and we observed that 1) SD exposure markedly reduced Kiss1 expression in the ARC and AVPV of male and female hamsters...

  17. Graduate nuclear engineering programmes motivate educational and research activities

    International Nuclear Information System (INIS)

    Mavko, B.

    2000-01-01

    Some fifteen years ago the University of Ljubljana, Faculty for Mathematics and Physics together with the national research organisation the J. Stefan jointly established a Graduate programme of Nuclear Engineering. From the onset, the programme focused on nuclear technology, nuclear safety, and reactor physics and environment protection. Over the years this graduate programme has became the focal point of nuclear related, research and educational activities in Slovenia. It has grown into a meeting ground for recognised national and distinguished foreign educators and experienced professionals from the industry. In conjunction with an important national project, supported by the Slovenian government, entitled 'Jung Researcher' it also enhances the knowledge transfer to the next generation. Since the programme was introduced, the interest for this programme has been steadily growing. Accordingly, a number of PhD and MS degrees in NE have been awarded. The graduates of this programme have encountered very good job opportunities in nuclear as well as in non-nuclear sector. (author)

  18. Diversity Programme Activity Report 2012-2015

    CERN Document Server

    Guinot, Genevieve; CERN. Geneva. HR Department

    2016-01-01

    CERN’s Diversity programme was launched in 2012 and is now firmly established as one of the pillars of the Organization’s Human Resources strategy. This report provides information on the actions undertaken in pursuit of the seven diversity strategic objectives set for the period from 2012 to 2015 in the priority areas identified for actions of recruitment, career development and work environment. The report highlights the progress made in anchoring the diversity principles in policies, procedures and practices within the Organization, as well as the persistent difficulties for the Organization to improve the representation of some nationalities and to attract female applicants in science and engineering. It shows a constant increase of female representation in managerial positions and encouraging results in building a diverse talent pool of scientists and engineers through the various student and graduate programmes. The report also outlines how the Diversity Office contributed through several actions,...

  19. Active Labour Market Programme Participation for Unemployment Insurance Recipients

    DEFF Research Database (Denmark)

    Filges, Trine; Smedslund, Geir; Jørgensen, Anne-Marie Klint

    2016-01-01

    Objective: This review evaluates the effectiveness of Active Labour Market Programme (ALMP) participation on employment status for unemployment insurance recipients. Methods and Analysis: We followed Campbell Collaboration guidelines to conduct a systematic review. Results: A total of 73 studies...

  20. Kiss-1/GPR54 protein expression in breast cancer.

    Science.gov (United States)

    Papaoiconomou, Eleni; Lymperi, Maria; Petraki, Constantina; Philippou, Anastassios; Msaouel, Pavlos; Michalopoulou, Fani; Kafiri, Georgia; Vassilakos, George; Zografos, Georgios; Koutsilieris, Michael

    2014-03-01

    Numerous studies have shown that the Kiss-1 gene countervails the metastatic aptitude of several cancer cell lines and solid-tumor neoplasias. However, there still remains ambiguity regarding its role in breast cancer and literature has arisen asserting that Kiss-1 expression may be linked to an aggressive phenotype and malignant progression. Herein, we investigated the protein expression of Kiss-1 and its receptor GPR54 in breast cancer tissues compared to non-cancerous mammary tissues. Paraffin-fixed cancer tissues from 43 women with resected breast adenocarcinomas and 11 specimens derived from women suffering from fibrocystic disease, serving as controls, were immunostained with Kiss-1 and GPR54 antibodies. Kiss-1 and GPR54 protein expression levels were significantly higher in breast cancer compared to fibrocystic tissues (pbreast cancer and fibrocystic disease specimens. Kiss-1/GPR54 expression was found to be significantly higher in breast cancer compared to non-malignant mammary tissues.

  1. Kiss-induced severe anaphylactic reactions

    Directory of Open Access Journals (Sweden)

    Atanasković-Marković Marina

    2010-01-01

    Full Text Available Introduction. Ingestion is the principal route for food allergens to trigger allergic reaction in atopic persons. However, in some highly sensitive patients severe symptoms may develop upon skin contact and by inhalation. The clinical spectrum ranges from mild facial urticaria and angioedema to life-threatening anaphylactic reactions. Outline of Cases. We describe cases of severe anaphylactic reactions by skin contact, induced by kissing in five children with prior history of severe anaphylaxis caused by food ingestion. These cases were found to have the medical history of IgE mediated food allergy, a very high total and specific serum IgE level and very strong family history of allergy. Conclusion. The presence of tiny particles of food on the kisser's lips was sufficient to trigger an anaphylactic reaction in sensitized children with prior history of severe allergic reaction caused by ingestion of food. Allergic reaction provoked with food allergens by skin contact can be a risk factor for generalized reactions. Therefore, extreme care has to be taken in avoiding kissing allergic children after eating foods to which they are highly allergic. Considering that kissing can be a cause of severe danger for the food allergic patient, such persons should inform their partners about the risk factor for causing their food hypersensitivity.

  2. Programme

    OpenAIRE

    Hobday, E, fl. 1905, artist

    2003-01-01

    A photograph of an illustrated programme listing dances. The illustration shows a snake charmer playing to a snake while another man watches. Buildings and trees can be seen behind a wall in the distance. In the lower right-hand corner of the programme is the signature 'E. Hobday'. The programme is almost certainly related to the Punjab Ball, Lahore. It is placed next to the Punjab Ball Menu in the album and the Menu is also illustrated by 'E. Hobday'.

  3. Metabolic Impact on the Hypothalamic Kisspeptin-Kiss1r Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Fazal Wahab

    2018-03-01

    Full Text Available A large body of data has established the hypothalamic kisspeptin (KP and its receptor, KISS1R, as major players in the activation of the neuroendocrine reproductive axis at the time of puberty and maintenance of reproductive capacity in the adult. Due to its strategic location, this ligand-receptor pair acts as an integrator of cues from gonadal steroids as well as of circadian and seasonal variation-related information on the reproductive axis. Besides these cues, the activity of the hypothalamic KP signaling is very sensitive to the current metabolic status of the body. In conditions of energy imbalance, either positive or negative, a number of alterations in the hypothalamic KP signaling pathway have been documented in different mammalian models including nonhuman primates and human. Deficiency of metabolic fuels during fasting causes a marked reduction of Kiss1 gene transcript levels in the hypothalamus and, hence, decreases the output of KP-containing neurons. Food intake or exogenous supply of metabolic cues, such as leptin, reverses metabolic insufficiency-related changes in the hypothalamic KP signaling. Likewise, alterations in Kiss1 expression have also been reported in other situations of energy imbalance like diabetes and obesity. Information related to the body’s current metabolic status reaches to KP neurons both directly as well as indirectly via a complex network of other neurons. In this review article, we have provided an updated summary of the available literature on the regulation of the hypothalamic KP-Kiss1r signaling by metabolic cues. In particular, the potential mechanisms of metabolic impact on the hypothalamic KP-Kiss1r signaling, in light of available evidence, are discussed.

  4. The international ISOE programme. ISOE IAEA technical centre activities

    International Nuclear Information System (INIS)

    Gustafsson, M.

    1996-01-01

    The objective of the sub-programme on Occupational Radiation Protection in the International Atomic Energy Agency, IAEA, is to promote a harmonized approach to optimizing occupational radiation protection by developing guidelines for controlling radiation doses in the workplace and on current occupational radiation protection techniques. A significant part of this programme is the provision of assistance to developing member states to bring their radiation safety infrastructure to an appropriate level for the usage of radiation in the state. In consistence with these objectives the IAEA has been involved with the ISOE programme from its inception and has contributed actively to its growth. In 1993 an arrangement was agreed between the IAEA and the Nuclear Energy Agency, NEA, by which the IAEA co-sponsors ISOE inviting those IAEA member states which are not members of the NEA to participate cost-free in the programme. (author)

  5. Long term results of kissing stents in the aortic bifurcation

    NARCIS (Netherlands)

    Hinnen, J.W.; Konickx, M.A.; Meerwaldt, Robbert; Kolkert, J.L.P.; van der Palen, Jacobus Adrianus Maria; Huisman, A.B.

    2015-01-01

    BACKGROUND: To evaluate the long-term outcome after aortoiliac kissing stent placement and to analyze variables, which potentially influence the outcome of endovascular reconstruction of the aortic bifurcation. METHODS: All patients treated with aortoiliac kissing stents at our institution between

  6. Kissing Bug ( spp. Intrusion into Homes: Troublesome Bites and Domiciliation

    Directory of Open Access Journals (Sweden)

    Stephen A. Klotz

    2016-01-01

    Full Text Available Kissing bugs ( Triatoma spp. frequently enter homes and bite human and pet occupants. Bites may lead to severe allergic reactions and, in some cases, death. Kissing bugs are also vectors of Trypanosoma cruzi , the cause of Chagas disease. In general, modern houses in the United States are not conducive to domiciliation of kissing bugs (bugs living out their entire life within the home with the presence of eggs, nymphs, adults, and exuviae. Construction features such as concrete foundations, solid walls and ceilings, window screens, tight thresholds for doors and windows, and other measures impede bug entry into homes, and air conditioning reduces the need for open doors and windows. Where Chagas disease is endemic in Mexico and Central and South America, homes often have thatch roofs, adobe walls, and open doors and windows. We investigated numerous instances of kissing bug intrusions into homes in Southern Arizona, California, and Louisiana and documented the reactions to kissing bug bites. Our work confirms the importance of modern home construction in limiting kissing bug intrusions. Older homes, especially those lacking modern screening, caulking, and weather stripping to reduce air leakage, may be subject to kissing bug intrusions and domiciliation. We describe a community in Southern Arizona where domiciliation of homes by Triatoma recurva is common. We also provide recent data regarding kissing bug bites and allergic reactions to the bites.

  7. DNA Characterization and Polymorphism of KISS1 Gene in Egyptian ...

    African Journals Online (AJOL)

    The objective of this study was the detection of the restriction fragment length polymorphism (RFLP) and single nucleotide polymorphisms (SNPs) of KISS1 gene in six major Egyptian small ruminant breeds. The primers used in this study flanked a 377 bp fragment from intron 1 of KISS1 gene in sheep and goat. These PCR ...

  8. Biennial activity report of Metallurgy Programme - 1985 and 1986

    International Nuclear Information System (INIS)

    Mallika, C.; Sreenivasan, P.R.; Muraleedharan, P.; Shyamsunder, M.T.; Kuppuswami, P.; Sampath, N.; Bhaduri, A.K.; Sreedharan, O.M.

    1988-01-01

    The biennial activity report of the Metallurgy Programme of the Indira Gandhi Centre for Atomic Research covers the period of the years 1985 and 1986. Along with NDT, welding metallurgy, low cycle fatigue, creep and creep fatigue interactions, structure-property correlations, thermodynamics and corrosion metallurgy of alloy steels with respect to their compatibility with aqueous and liquid sodium environments continue to be the major thrust areas of the Programme. Some of the basic research contributions of the Programme are: the observation of uniform and homogeneous distribution of voids in cyclically deformed 304 SS, the role of grain boundaries and precipitation in dynamic strain ageing of 316 SS and the determination of the activities of component metals in 316 and 304 SS by metastable EMF method. (author)

  9. Primer on CDM programme of activities

    Energy Technology Data Exchange (ETDEWEB)

    Hinostroza, M. (UNEP Risoe Centre, Roskilde (Denmark)); Lescano, A.D. (A2G Carbon Partners (Peru)); Alvarez, J.M. (Ministerio del Ambiente del Peru (Peru)); Avendano, F.M. (EEA Fund Management Ltd. (United Kingdom)

    2009-07-01

    As an advanced modality introduced in 2005, the Programmatic CDM (POA) is expected to address asymmetries of participation, especially of very small-scale project activities in certain areas, key sectors and many countries with considerable potential for greenhouse gas emission reductions, not reached by the traditional single-project-based CDM. Latest experiences with POAs and the recently finalized official guidance governing the Programmatic CDM are the grassroots of this Primer, which has the purpose of supporting the fully understanding of rules and procedures of POAs by interpreting them and analyzing real POA cases. Professional and experts from the public and private entities have contributed to the development of this Primer, produced by the UNEP Risoe Centre, as part of knowledge support activities for the Capacity Development for the CDM (CD4CDM) project. The overall objective of the CD4CDM is to develop the capacities of host countries to identify, design, approve, finance, implement CDM projects and commercialize CERs in participating countries. The CDM4CDM is funded by the Netherlands Ministry of Foreign Affairs. (author)

  10. The role of active teaching programmes in academic skills ...

    African Journals Online (AJOL)

    The role of active teaching programmes in academic skills enhancement of Grade 12 Learners in the Stellenbosch Region. ... The premise of this study focused on the holistic approach to the human body, mainly the connection between the brain and the body. Learners attend school as holistic beings and both the body ...

  11. Effects of a water activity intervention programme on motor ...

    African Journals Online (AJOL)

    The aim of this study was to investigate the effect of a specially designed water activity programme on the motor competency levels of children with Down's syndrome. Six institutionalised children classified as having Down\\'s syndrome, from a school for the mentally retarded, took part in the study. The children\\'s ...

  12. Assessment of nutrition and physical activity education programmes in children.

    Science.gov (United States)

    Burke, V; Beilin, L J; Milligan, R; Thompson, C

    1995-03-01

    1. Studies in children relating blood lipids to the extent of atherosclerosis at post-mortem suggest a link between risk factors for cardiovascular disease in childhood and adult life. Tracking of blood pressure (BP) and cholesterol from childhood also supports this association. However, prospective studies have not yet established the outcome in children with increased levels of risk factors. 2. In a controlled trial in Perth, Western Australia, involving over 1000 10-12 year old children, fitness was improved by physical activity programmes which were associated with a greater fall in diastolic BP and triceps skinfolds in girls compared with controls. Sugar intake decreased in boys and fat intake fell in girls, mainly affecting participants in home nutrition programmes. 3. In higher risk children, identified by cluster analysis, major benefits were associated with the fitness and home nutrition programmes. Physical activity combined with involvement of the family in nutrition education is likely to be the most successful approach to modifying lifestyle in children, including those with higher levels of risk. 4. Undernutrition by too rigid restriction of fat intake must be avoided in young children who need calorie-dense foods. Undernutrition, in itself, may predispose to cardiovascular disease in later life. Programmes should aim to establish a prudent diet appropriate to the age of the child combined with physical activity. As regular activity and a healthy diet in adult life will reduce risks of cardiovascular disease it is likely that childhood education will establish lifestyle habits of potential long-term benefit.

  13. Costs and benefits of Danish active labour market programmes

    DEFF Research Database (Denmark)

    Jespersen, Svend; Munch, Jakob Roland; Skipper, Lars

    2008-01-01

    Since 1994, unemployed workers in the Danish labour market have participated in active labour market programmes on a large scale. This paper contributes with an assessment of costs and benefits of these programmes. Long-term treatment effects are estimated on a very detailed administrative dataset...... prospects in the long run. When the cost side is taken into account, private and public job training still come out with surplusses, while classroom training leads to a deficit....... by propensity score matching. For the years 1995 - 2005 it is found that private job training programmes have substantial positive employment and earnings effects, but also public job training ends up with positive earnings effects. Classroom training does not significantly improve employment or earnings...

  14. Having Fun with Organized Kissing: A Pedagogical Note

    OpenAIRE

    Jong-Shin Wei

    2008-01-01

    Harbaugh's daughter went to a French school at which every day before class, everyone in the class must kiss each other. It is easy to see that a class of 35 kids must engage in 595 kisses. Organizing the kissing for the purpose of time-saving and predicting how much time it would take are proposed in this pedagogical note inspired by the entertaining puzzle made by Harbaugh. We also illustrate how this problem-solving case study, requiring no mathematics but careful reasoning, might be incor...

  15. Gravity's kiss the detection of gravitational waves

    CERN Document Server

    Collins, Harry

    2017-01-01

    Scientists have been trying to confirm the existence of gravitational waves for fifty years. Then, in September 2015, came a "very interesting event" (as the cautious subject line in a physicist's email read) that proved to be the first detection of gravitational waves. In Gravity's Kiss, Harry Collins -- who has been watching the science of gravitational wave detection for forty-three of those fifty years and has written three previous books about it -- offers a final, fascinating account, written in real time, of the unfolding of one of the most remarkable scientific discoveries ever made. Predicted by Einstein in his theory of general relativity, gravitational waves carry energy from the collision or explosion of stars. Dying binary stars, for example, rotate faster and faster around each other until they merge, emitting a burst of gravitational waves. It is only with the development of extraordinarily sensitive, highly sophisticated detectors that physicists can now confirm Einstein's prediction. This is...

  16. Family matters: Directionality of turning bias while kissing is modulated by context.

    Science.gov (United States)

    Sedgewick, Jennifer R; Elias, Lorin J

    2016-01-28

    When leaning forward to kiss to a romantic partner, individuals tend to direct their kiss to the right more often than the left. Studies have consistently demonstrated this kissing asymmetry, although other factors known to influence lateral biases, such as sex or situational context, had yet to be explored. The primary purpose of our study was to investigate if turning direction was consistent between a romantic (parent-parent) and parental (parent-child) kissing context, and secondly, to examine if sex differences influenced turning bias between parent-child kissing partners. An archival analysis coded the direction of turning bias for 161 images of romantic kissing (mothers kissing fathers) and 529 images of parental kissing (mothers or fathers kissing sons or daughters). The results indicated that the direction of turning bias differed between kissing contexts. As expected, a right-turn bias was observed for romantic kissing; however, a left-turn bias was exhibited for parental kissing. There was no significant difference of turning bias between any parent-child kissing partners. Interpretations for the left-turn bias discuss parental kissing as a learned lateral behaviour.

  17. Recent Activities on the Experimental Research Programme Using Small Tokamaks

    International Nuclear Information System (INIS)

    Gryaznevich, M. P.; Bosco, E. del; Malaquias, A.; Mank, G.; Oost, G. van

    2006-01-01

    A new concept of interactive co-ordinated research using small tokamaks in the mainstream fusion science areas, in testing of new diagnostics, materials and technologies as well as in education, training and broadening of the geography of fusion research in the scope of the IAEA Co-ordinated Research Project (CRP) is discussed in this paper. Besides the presentation of the recent activities on the experimental research programme using small tokamaks and scientific results achieved at the participating laboratories, information is provided about the organisation of the co-ordinated research project. Future plans of the co-ordinated activities within the CRP are discussed

  18. Non-Destructive Evaluation of Kissing Bonds using Local Defect Resonance (LDR) Spectroscopy: A Simulation Study

    Science.gov (United States)

    Delrue, S.; Tabatabaeipour, M.; Hettler, J.; Van Den Abeele, K.

    With the growing demand from industry to optimize and further develop existing Non-Destructive Testing & Evaluation (NDT&E) techniques or new methods to detect and characterize incipient damage with high sensitivity and increased quality, ample efforts have been devoted to better understand the typical behavior of kissing bonds, such as delaminations and cracks. Recently, it has been shown experimentally that the nonlinear ultrasonic response of kissing bonds could be enhanced by using Local Defect Resonance (LDR) spectroscopy. LDR spectroscopy is an efficient NDT technique that takes advantage of the characteristic fre- quencies of the defect (defect resonances) in order to provide maximum acoustic wave-defect interaction. In fact, for nonlinear methodologies, the ultrasonic excitation of the sample should occur at either multiples or integer ratios of the characteristic defect resonance frequencies, in order to obtain the highest signal-to-noise response in the nonlinear LDR spectroscopy. In this paper, the potential of using LDR spectroscopy for the detection, localization and characterization of kissing bonds is illustrated using a 3D simulation code for elastic wave propagation in materials containing closed but dynamically active cracks or delaminations. Using the model, we are able to define an appropriate method, based on the Scaling Subtraction Method (SSM), to determine the local defect resonance frequencies of a delamination in a composite plate and to illustrate an increase in defect nonlinearity due to LDR. The simulation results will help us to obtain a better understanding of the concept of LDR and to assist in the further design and testing of LDR spectroscopy for the detection, localization and characterization of kissing bonds.

  19. Issues related to a programme of activities under the CDM

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, J.

    2006-05-15

    Emissions of CO2 from the energy and land-use change and forestry sectors are responsible for the majority of emissions in non-Annex I Parties to the UNFCCC. Tackling greenhouse gas (GHG) emissions from these sectors is a key to slowing the growth in GHG emissions in non-Annex I countries. Implementing Clean Development Mechanism (CDM) projects can help achieve this aim, while also assisting non-Annex I countries to move towards sustainable development and Annex I countries achieve their emission commitments under the Kyoto Protocol. There has been rapid progress in the CDM over the last year - in terms of the number of projects in the pipeline and registered, and in terms of credits issued. However, some important sectors are notable by their small share in the CDM portfolio. Several countries have also called attention to the need to accelerate the process of approving CDM methodologies and projects. In order to improve the effectiveness of the CDM to achieve its dual objectives, the COP/MOP agreed a decision on 'further guidance relating to the clean development mechanism. This decision lays out guidance on how to improve the operation of the CDM, and includes provisions that allow: (1) Bundling of project activities; and (2) Project activities under a programme of activities, to be registered as a CDM project activity. At present, of the 172 currently registered CDM project activities, 27 involve programmes or bundles. These project activities can include more than one project type, be implemented in several locations, and/or occur in more than one sector. This paper assesses how project activities under a programme of activities under the CDM (referred to here as PCDM) could help to increase the effectiveness of the CDM by encouraging a wide spread of emission mitigation activities. This paper also explores the key issues that may need to be considered for the PCDM concept to be further implemented. The paper concludes that: (1) Key concepts and issues

  20. Sex Differences in Romantic Kissing among College Students: An Evolutionary Perspective

    Directory of Open Access Journals (Sweden)

    Susan M. Hughes

    2007-07-01

    Full Text Available This study provides a descriptive account of kissing behavior in a large sample of undergraduate college students and considers kissing in the context of both short-term and long-term mating relationships. Kissing was examined as a mate assessment device, a means of promoting pair bonds, and a means of inducing sexual arousal and receptivity. A total 1,041 college students completed one of three questionnaires measuring kissing preferences, attitudes, styles, and behaviors. Results showed that females place more importance on kissing as a mate assessment device and as a means of initiating, maintaining, and monitoring the current status of their relationship with a long-term partner. In contrast, males place less importance on kissing, especially with short-term partners, and appear to use kissing to increase the likelihood of having sex. The results suggest that kissing may play an important role as an adaptive courtship/mating ritual.

  1. Active ingredients in anti-stigma programmes in mental health.

    Science.gov (United States)

    Pinfold, Vanessa; Thornicroft, Graham; Huxley, Peter; Farmer, Paul

    2005-04-01

    This paper draws upon a review of the relevant literature and the results of the recent Mental Health Awareness in Action (MHAA) programme in England to discuss the current evidence base on the active ingredients in effective anti-stigma interventions in mental health. The MHAA Programme delivered educational interventions to 109 police officers, 78 adults from different community groups whose working lives involved supporting people with mental health problems but who had received no mental health training and 472 schools students aged 14-15. Each adult target group received two intervention sessions lasting two hours. The two school lessons were 50 minutes each. Knowledge, attitudes and behavioural intent were assessed at baseline and follow-up. In addition focus groups were held with mental health service users to explore the impact of stigma on their lives and facilitators of educational workshops were interviewed to provide expert opinion on 'what works' to reduce psychiatric stigma. Personal contact was predictive of positive changes in knowledge and attitudes for the school students but not the police officers or community adult group. The key active ingredient identified by all intervention groups and workshop facilitators were the testimonies of service users. The statements of service users (consumers) about their experience of mental health problems and of their contact with a range of services had the greatest and most lasting impact on the target audiences in terms of reducing mental health stigma.

  2. Energy policy fundamentals research programme - Activities and projects in 2002

    International Nuclear Information System (INIS)

    Meier, R.; Previdoli, P.

    2003-01-01

    This annual report for the Swiss Federal Office of Energy reviews the activities and projects carried out within the Swiss Confederation's Energy Policy Fundamentals Research programme during 2002. The programme's main centres of activity are described, including projects involving the acquisition of data on indicators of selected cantonal energy saving measures, the possibility of reducing carbon dioxide emissions by influencing fuel prices, new construction instead of refurbishment of buildings, internalisation of risks involved with nuclear power and the marginal costs of intensified energy-efficiency measures. In the technology monitoring area, the results of studies concerning combined heat and power systems, heat pumps and fuel cells are reviewed. Further projects are described in the building and fuel supply areas and the influence of wind power on European peak power requirements is examined. Marketing aspects concerning the thermal use of solar energy and low energy consumption housing are discussed, as is the promotion of energy efficiency in housing and industry. Also local and regional efforts being made in the energy policy area are described. The report is rounded off with a list of the various projects mentioned in the report and appropriate contact information

  3. Applying a nonlinear, pitch-catch, ultrasonic technique for the detection of kissing bonds in friction stir welds.

    Science.gov (United States)

    Delrue, Steven; Tabatabaeipour, Morteza; Hettler, Jan; Van Den Abeele, Koen

    2016-05-01

    Friction stir welding (FSW) is a promising technology for the joining of aluminum alloys and other metallic admixtures that are hard to weld by conventional fusion welding. Although FSW generally provides better fatigue properties than traditional fusion welding methods, fatigue properties are still significantly lower than for the base material. Apart from voids, kissing bonds for instance, in the form of closed cracks propagating along the interface of the stirred and heat affected zone, are inherent features of the weld and can be considered as one of the main causes of a reduced fatigue life of FSW in comparison to the base material. The main problem with kissing bond defects in FSW, is that they currently are very difficult to detect using existing NDT methods. Besides, in most cases, the defects are not directly accessible from the exposed surface. Therefore, new techniques capable of detecting small kissing bond flaws need to be introduced. In the present paper, a novel and practical approach is introduced based on a nonlinear, single-sided, ultrasonic technique. The proposed inspection technique uses two single element transducers, with the first transducer transmitting an ultrasonic signal that focuses the ultrasonic waves at the bottom side of the sample where cracks are most likely to occur. The large amount of energy at the focus activates the kissing bond, resulting in the generation of nonlinear features in the wave propagation. These nonlinear features are then captured by the second transducer operating in pitch-catch mode, and are analyzed, using pulse inversion, to reveal the presence of a defect. The performance of the proposed nonlinear, pitch-catch technique, is first illustrated using a numerical study of an aluminum sample containing simple, vertically oriented, incipient cracks. Later, the proposed technique is also applied experimentally on a real-life friction stir welded butt joint containing a kissing bond flaw. Copyright © 2016

  4. Future strategies on IAEA activities and technical cooperation programmes

    International Nuclear Information System (INIS)

    Kim, Kyoung Pyo; Hong, Young Don

    1998-10-01

    This study provides basic background information about the establishment of the IAEA, its mission, major activities, General Conference , and Board of Governors, structure and functions of the Secretariat. The IAEA Mid-term plan, to be implemented in the years 1998 - 2003, includes the enhancement of its functional effectiveness, analysis of the changing developments, adjustment of its priorities, and evaluation of its programmes, are describes in full detail. This plan is divided into 6 major areas ; nuclear power and the fuel cycle, nuclear applications, nuclear, radiation and radwaste safety, verification and security of nuclear material, management of technical cooperation for development, policy making, coordination and support. It is also expected that the IAEA plan provides an opportunity to understand the future directions of IAEA programmes and its operational philosophy, thus greatly contributing to Koreas establishment of its own future directions for expanded cooperation with the IAEA, and urges to device effective domestic strategies. This plan will also contribute to the evaluation of Koreas responsibility as a member of the Board of Governors as well as enhance Koreas role as an Advisory Group Member. It is expected that this study is useful for nuclear-related organizations wishing to establish basic directions for the efficient implementation of IAEA technical cooperation programs in the future. (author). 16 refs., 6 tabs., 16 figs

  5. The Medical Activation Analysis Research Programme of the IAEA Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Parr, R. M. [Medical Applications Section, International Atomic Energy Agency, Vienna (Austria)

    1970-07-01

    Analyses carried out under the Agency's laboratory programme in medical activation analysis commended in 1967. This paper describes the laboratory facilities and experimental methods now in use, and reports briefly on results obtained to date. The analytical scheme places greatest emphasis on non-destructive methods (i.e. without radiochemistry), and by the use of a Ge(Li) detector and a 2-parameter Nal(Tl) gamma-ray spectrometer, presently allows the determination of up to 12 elements in unprocessed tissue samples. Projects completed or underway include (i) an investigation into the uniformity of distribution of mineral elements in human liver, (ii) studies of tissue concentrations of trace elements in relation to malnutrition and cardiovascular diseases, and (iii) the determination of iodine in food, natural waters and other biological materials in relation to the epidemiology of endemic goitre. (author)

  6. The international ISOE programme. ISOE European technical centre activities

    International Nuclear Information System (INIS)

    Ascenzo, L. d'; Crouail, P.; Levy, F.; Livolsi, P.; Schieber, C.; Lefaure, C.

    1996-01-01

    The CEPN has been involved from the beginning in the NEA Information System on Occupational Exposure (ISOE). As ISOE European Technical Centre, the CEPN is responsible for the collection and distribution of European data to the various ISOE partners, the collection of data from the other regional technical centres, and the custodianship of the full ISOE data base. This full data base is updated annually and distributed to all the European participating utilities and to other Regional Technical Centres. The European data are also sent to the European Commission (EC) as a contribution to their own occupational exposure data base. In addition to these activities, the CEPN has developed two computer programmes under Windows to facilitate the management of ISOE data bases. The first software, called ASPIC, allows participating utilities to electronically complete NEA1 and NEA3 questionnaires, as well as to consult the NEA3 data base using key words search routine. This software is available in six different languages. The second programme is a relational data base for the performance of statistical analyses using data from NEA1. The CEPN also contributes significantly to the efficient flow of information through the ISOE Network. This includes participation in the preparation and distribution of the ISOE Annual Report (which presents and analyses NEAI data), ISOE Information Sheets (providing short synthesis using NEA1 and NEA3 data), and Technical Reports. Participating Authorities and Utilities have each made information requests to the CEPN concerning dosimetric data, radiation protection experiences, policies and practices. Some examples of these requests, and of the types of data provided, will be presented. (author)

  7. "I kiss them because I love them": the emergence of heterosexual men kissing in British institutes of education.

    Science.gov (United States)

    Anderson, Eric; Adams, Adi; Rivers, Ian

    2012-04-01

    In this article, we combined data from 145 interviews and three ethnographic investigations of heterosexual male students in the U.K. from multiple educational settings. Our results indicate that 89% have, at some point, kissed another male on the lips which they reported as being non-sexual: a means of expressing platonic affection among heterosexual friends. Moreover, 37% also reported engaging in sustained same-sex kissing, something they construed as non-sexual and non-homosexual. Although the students in our study understood that this type of kissing remains somewhat culturally symbolized as a taboo sexual behavior, they nonetheless reconstructed it, making it compatible with heteromasculinity by recoding it as homosocial. We hypothesize that both these types of kissing behaviors are increasingly permissible due to rapidly decreasing levels of cultural homophobia. Furthermore, we argue that there has been a loosening of the restricted physical and emotional boundaries of traditional heteromasculinity in these educational settings, something which may also gradually assist in the erosion of prevailing heterosexual hegemony.

  8. Molecular characterization of Kiss2 receptor and in vitro effects of Kiss2 on reproduction-related gene expression in the hypothalamus of half-smooth tongue sole (Cynoglossus semilaevis).

    Science.gov (United States)

    Wang, Bin; Liu, Quan; Liu, Xuezhou; Xu, Yongjiang; Shi, Bao

    2017-08-01

    Kisspeptin (Kiss) and its receptor, KissR (previously known as GPR54), play a critical role in the control of reproduction and puberty onset in mammals. Additionally, a number of studies have provided evidence of the existence of multiple Kiss/KissR systems in teleosts, but the physiological relevance and functions of these kisspeptin forms (Kiss1 and Kiss2) still remain to be investigated. To this end, we examined the direct actions of Kiss2 on hypothalamic functions in the half-smooth tongue sole (Cynoglossus semilaevis), a representative species of the order Pleuronectiformes. As a first step, the full-length cDNA for kiss2r was identified and kiss2r transcripts were shown to be widely expressed in various tissues, notably in the brain of tongue sole. Then, the effects of Kiss2 decapeptide on reproduction-related gene expression were evaluated using a primary hypothalamus culture system. Our results showed that neither gnrh2 nor gnrh3 mRNA levels were altered by Kiss2. However, Kiss2 significantly increased the amounts of gnih and kiss2 mRNAs. In contrast, Kiss2 elicited an evident inhibitory effect on both gnihr and kiss2r mRNA levels. To the best of our knowledge, this is the first description of a direct and differential regulation of reproduction-related gene expression by Kiss2 at the hypothalamus level of a teleost fish. Overall, this study provides novel information on the role of Kiss2/Kiss2R system in the reproductive function of teleosts. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Programme Costing of a Physical Activity Programme in Primary Prevention: Should the Costs of Health Asset Assessment and Participatory Programme Development Count?

    Directory of Open Access Journals (Sweden)

    Silke B. Wolfenstetter

    2012-01-01

    Full Text Available This analysis aims to discuss the implications of the “health asset concept”, introduced by the WHO, and the “investment for health model” requiring a “participatory approach” of cooperative programme development applied on a physical activity programme for socially disadvantaged women and to demonstrate the related costing issues as well as the relevant decision context. The costs of programme implementation amounted to €48,700. Adding the costs for developing the programme design of €48,800 results in total costs of €97,500; adding on top of that the costs of asset assessment running to €35,600 would total €133,100. These four different cost figures match four different types of potentially relevant decisions contexts. Depending on the decision context the total costs, and hence the incremental cost-effectiveness ratio of a health promotion intervention, could differ considerably. Therefore, a detailed cost assessment and the identification of the decision context are of crucial importance.

  10. Electricity research programme - Overview report on activities in 2005; Programm Elektrizitaet. Ueberblicksbericht zum Forschungsprogramm 2005

    Energy Technology Data Exchange (ETDEWEB)

    Brueniger, R.

    2006-07-01

    This overview-report for the Swiss Federal Office of Energy (SFOE) summarises the work done in 2005 in the various research areas covered by the Swiss Electricity Research programme. Work done in the programme's two main areas - technologies and efficient applications - is reviewed. In the technologies area, high-temperature superconductivity - and especially its use in power-generation facilities - is looked at, as are the topics of energy conversion and thermo-electric power generation. Further, energy storage using compressed-air is discussed. Power distribution and the use of controllable storage in the low-voltage mains is briefly commented on, as is distributed power generation. Information and communications technologies are reviewed, as is work done in the electrical drives area. Work in other areas summarised includes lighting and uninterruptible power-supplies. Co-operation with Swiss institutions and international organisations such as the IEA is reviewed. Implementation work in the pilot and demonstration area is commented on. This includes work in various areas ranging from set-top boxes through to the optimisation of compressed-air systems and electrical drives as well as codes of conduct and agreements for water-dispensers and cooling systems in retail applications and the optimisation of wastewater treatment plant. The report is completed with a list of current research and development projects.

  11. 2014 ICSA/KISS Joint Applied Statistics Symposium

    CERN Document Server

    Liu, Mengling; Luo, Xiaolong

    2016-01-01

    The papers in this volume represent the most timely and advanced contributions to the 2014 Joint Applied Statistics Symposium of the International Chinese Statistical Association (ICSA) and the Korean International Statistical Society (KISS), held in Portland, Oregon. The contributions cover new developments in statistical modeling and clinical research: including model development, model checking, and innovative clinical trial design and analysis. Each paper was peer-reviewed by at least two referees and also by an editor. The conference was attended by over 400 participants from academia, industry, and government agencies around the world, including from North America, Asia, and Europe. It offered 3 keynote speeches, 7 short courses, 76 parallel scientific sessions, student paper sessions, and social events. The most timely and advanced contributions from the joint 2014 ICSA/KISS Applied Statistics Symposium All papers feature original, peer-reviewed content Coverage consists of new developments in statisti...

  12. K.I.S.S. Parallel Coding (lecture 2)

    CERN Multimedia

    CERN. Geneva

    2018-01-01

    K.I.S.S.ing parallel computing means, finally, loving it. Parallel computing will be approached in a theoretical and experimental way, using the most advanced and used C API: OpenMP. OpenMP is an open source project constantly developed and updated to hide the awful complexity of parallel coding in an awesome interface. The result is a tool which leaves plenty of space for clever solutions and terrific results in terms of efficiency and performance maximisation.

  13. Earth observation space programmes, SAFISY activities, strategies of international organisations, legal aspects. Volume 3

    International Nuclear Information System (INIS)

    1992-01-01

    This volume is separated in four sessions. First part is on earth observation space programmes (international earth observation projects and international collaboration, the ERS-1, SPOT and PRIRODA programmes, the first ESA earth observation polar platform and its payload, the future earth observation remote sensing techniques and concepts). The second part is on SAFISY activities (ISY programmes, education and applications, demonstrations and outreach projects). The third part is on programme and strategies of international organisations with respect to earth observation from space. The fourth part is on legal aspects of the use of satellite remote sensing data in Europe. (A.B.). refs., figs., tabs

  14. Cash transfer programme, productive activities and labour supply: Evidence from randomized experiment in Kenya

    Science.gov (United States)

    Asfaw, Solomon; Davis, Benjamin; Dewbre, Josh; Handa, Sudhanshu; Winters, Paul

    2015-01-01

    This paper reports analysis of the impact of Kenya’s Cash Transfer for Orphans and Vulnerable Children Programme on the household decisions on productive activities using data from a randomized experimental design. Results show that the programme had a positive and significant impact on food consumption coming from home production, accumulation of productive assets, especially on the ownership of small livestock and on formation of nonfarm enterprise, especially for females. The programme has provided more flexibility to families in terms of labour allocation decisions, particularly for those who are geographically isolated. The programme was also found to have reduced child labour, an important objective of the programme. However we find very little impact of the programme on direct indicators of crop production. PMID:25663712

  15. Gardening with Huntington's disease clients--creating a programme of winter activities.

    Science.gov (United States)

    Spring, Josephine Anne; Baker, Mark; Dauya, Loreane; Ewemade, Ivie; Marsh, Nicola; Patel, Prina; Scott, Adrienne; Stoy, Nicholas; Turner, Hannah; Viera, Marc; Will, Diana

    2011-01-01

    A programme of garden-related indoor activities was developed to sustain a gardening group for people with mid to late stage Huntington's disease during the winter. The activities were devised by the horticulturist, working empirically, involving the services occupational therapist, physiotherapist, occupational therapy art technician, computer room, recreation and leisure staff. The programme was strongly supported by the nursing and care staff. Feedback on the effectiveness of the activities was sought from the clients, team members and unit staff. The clients' interest in gardening was sustained by a multidisciplinary programme of indoor growing and using plant products in creative activities, computing and group projects. The clients enjoyed all activities except one that they said lacked contact with plants. The inexpensive programme of activities enabled creativity and self-expression, stimulated social contact and helped with therapeutic goals of the clients. In addition, it engaged the multi-disciplinary team and the unit staff, was practical and enhanced the environment.

  16. Developing international alumni activities in Mikkeli University of Applied Sciences : Case Business Management degree programme

    OpenAIRE

    Honkaniemi, Meri

    2014-01-01

    My thesis focuses on international alumni activities in Mikkeli University of Applied Sciences. My aim was to find development ideas and recommendations for the international side of the alumni activities. I intended to offer realistic suggestions enough in order to make them work in practice too. I put also my effort on finding recommendations for Business Management programme, because I wanted to make sure that international alumni activities get attention in degree programme level too. ...

  17. Combustion chemistry - activities in the CHEK research programme

    Energy Technology Data Exchange (ETDEWEB)

    Dam-Johansen, K.; Johnsson, J.E.; Glarborg, P.; Frandsen, F.; Jensen, A.; Oestberg, M. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Chemical Engineering

    1997-10-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This presentation describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control) Research Programme. (orig.)

  18. A framework for evaluating community-based physical activity promotion programmes in Latin America.

    Science.gov (United States)

    Schmid, Thomas L; Librett, John; Neiman, Andrea; Pratt, Michael; Salmon, Art

    2006-01-01

    A growing interest in promoting physical activity through multi-sectoral community-based programmes has highlighted the need for effective programme evaluation. Meeting in Rio de Janeiro, an international workgroup of behavioural, medical, public health and other scientists and practitioners endorsed the principle of careful evaluation of all programmes and in a consensus process developed the Rio de Janeiro Recommendations for Evaluation of Physical Activity Interventions". Among these recommendations and principles were that when possible, evaluation should 'built into' the programme from the beginning. The workgroup also called for adequate funding for evaluation, setting a goal of about 10% of programme resources for evaluation. The group also determined that evaluations should be developed in conjunction with and the results shared with all appropriate stakeholders in the programme; evaluations should be guided by ethical standards such as those proposed by the American Evaluation Association and should assess programme processes as well as outcomes; evaluation outcomes should be used to revise and refine ongoing programmes and guide decisions about programme continuation or expansion. It was also recognised that additional training in programme evaluation is needed and the Centers for Disease Control and Prevention's Physical Activity Evaluation Handbook could be easily adapted for use in culturally diverse communities, especially in Latin America. This paper describes a 6-step evaluation process and provides the full set of recommendations from the Rio de Janeiro Workgroup. The handbook has been translated and additional case studies from Colombia and Brazil have been added. Spanish and Portuguese language editions of the Evaluation Handbook are available from the Centers for Disease Control and Prevention, Physical Activity and Health Branch.

  19. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    2009-01-01

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  20. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  1. KISS: strategie tlumočníka při simultánním tlumočení do mateřštiny a do aktivního cizího jazyka : zkoumáno na česko-francouzském materiálu

    OpenAIRE

    Malkovská, Alžběta

    2009-01-01

    This thesis focuses on the topic of the KISS strategy ("Keep it short and simple") as a hypothetical ideal solution for simultaneous interpreting into the active language. The purpose of this theoretical and empirical study is to describe the issue of interpreting into the active language (B language) and the strategies used in simultaneous interpreting, with emphasis on the KISS strategy. The paper is divided into two parts: theoretical part and empirical part. In the theoretical part, we se...

  2. Corporate sponsorship of physical activity promotion programmes: part of the solution or part of the problem?

    OpenAIRE

    Jane, Ben; Gibson, Kass

    2017-01-01

    Background\\ud Parklives is a programme intended to raise levels of physical activity across the UK, funded by Coca-Cola GB and delivered in association with Local Authorities and other organizations. Such public-private partnerships have been advocated by many however critics suggest that the conflict between stakeholder motives is too great.\\ud Methods\\ud This study conducted a content analysis of twitter content related to the ParkLives physical activity programme. Images and text were anal...

  3. Combustion chemistry. Activities in the CHEC research programme

    Energy Technology Data Exchange (ETDEWEB)

    Dam-Johansen, K; Johnsson, J E; Glarborg, P; Frandsen, F; Jensen, A; Oestberg, M [Technical Univ. of Denmark, Dept. of Chemical Engineering, Lyngby (Denmark)

    1996-12-01

    The combustion chemistry in the oxidation of fossil fuels and biofuels determines together with mixing and heat transfer the required size of a furnace, the emission of gaseous pollutants, and the formation of ash and deposits on surfaces. This paper describes technologies for solid fuels combustion and gives a summary of the fuels, the pollutant chemistry and the inorganic chemistry in combustion processes. Emphasis is put on the work carried out in the CHEC (Combustion and Harmful Emission Control Research Programme). (au) 173 refs.

  4. Evidence for a role of KISS-1/GPR54 system in decreased ...

    African Journals Online (AJOL)

    Short fasting has been shown to suppress luteinizing hormone (LH) secretion in ewes, however, the molecular mechanism underlying this phenomenon is not clear. Based on recent discovery of the crucial role of KiSS-1/GPR54 system in the central control of the GnRH axis, we hypothesized that KiSS-1/GPR54 system was ...

  5. Kissing Bug (Triatoma spp.) Intrusion into Homes: Troublesome Bites and Domiciliation.

    Science.gov (United States)

    Klotz, Stephen A; Shirazi, F Mazda; Boesen, Keith; Beatty, Norman L; Dorn, Patricia L; Smith, Shannon; Schmidt, Justin O

    2016-01-01

    Kissing bugs (Triatoma spp.) frequently enter homes and bite human and pet occupants. Bites may lead to severe allergic reactions and, in some cases, death. Kissing bugs are also vectors of Trypanosoma cruzi, the cause of Chagas disease. In general, modern houses in the United States are not conducive to domiciliation of kissing bugs (bugs living out their entire life within the home with the presence of eggs, nymphs, adults, and exuviae). Construction features such as concrete foundations, solid walls and ceilings, window screens, tight thresholds for doors and windows, and other measures impede bug entry into homes, and air conditioning reduces the need for open doors and windows. Where Chagas disease is endemic in Mexico and Central and South America, homes often have thatch roofs, adobe walls, and open doors and windows. We investigated numerous instances of kissing bug intrusions into homes in Southern Arizona, California, and Louisiana and documented the reactions to kissing bug bites. Our work confirms the importance of modern home construction in limiting kissing bug intrusions. Older homes, especially those lacking modern screening, caulking, and weather stripping to reduce air leakage, may be subject to kissing bug intrusions and domiciliation. We describe a community in Southern Arizona where domiciliation of homes by Triatoma recurva is common. We also provide recent data regarding kissing bug bites and allergic reactions to the bites.

  6. Endovascular Treatment of Occlusive Lesions in the Aortic Bifurcation with Kissing Polytetrafluoroethylene-Covered Stents

    NARCIS (Netherlands)

    Grimme, F.A.B.; Spithoven, J.H.; Zeebregts, C.J.A.; Scharn, D.M.; Reijnen, M.M.

    2015-01-01

    PURPOSE: To determine the clinical outcomes of polytetrafluoroethylene covered balloon expandable stents (CBESs) in occlusive lesions of the aortic bifurcation in a kissing stent configuration. MATERIALS AND METHODS: The study included 69 consecutive patients (29 men, 40 women) who underwent kissing

  7. Endovascular Treatment of Occlusive Lesions in the Aortic Bifurcation with Kissing Polytetrafluoroethylene-Covered Stents

    NARCIS (Netherlands)

    Grimme, Frederike A. B.; Spithoven, J. Hans; Zeebregts, Clark J.; Scharn, Dirk M.; Reijnen, Michel M. P. J.

    Purpose: To determine the clinical outcomes of polytetrafluoroethylene covered balloon expandable stents (CBESs) in occlusive lesions of the aortic bifurcation in a kissing stent configuration. Materials and Methods: The study included 69 consecutive patients (29 men, 40 women) who underwent kissing

  8. Adult Workers in Theory or Practice? : Lone Mothers’ Participation in Active Labour Market Programmes in Germany

    Directory of Open Access Journals (Sweden)

    Cordula Zabel

    2015-03-01

    Full Text Available This paper examines lone mothers’ participation in active labour market programmes in Germany. Since the 2005 Hartz IV employment and welfare policy reforms, expectations that non-em- ployed parents receiving means-tested benefits should be ready for employment or labour market programme participation have grown stronger. However, discretion for programme assignments is left to individual caseworkers. As a consequence, it is not clear to what extent the formal policy orientation towards an adult worker model of the family is reflected in practical policy implemen- tations. Thus, lone mothers’ participation in active labour market programmes is studied empiri- cally here on the basis of large-scale administrative data, using event-history analysis. Findings are that lone mothers are treated as adult workers with respect to workfare and training pro- grammes even when their children are still quite young. As soon as their youngest child is 3 - 5 years old, lone mothers’ transition rates into these programmes are as high as for childless single women. In the case of programmes that provide more direct pathways into regular employment, like job subsidies and in-firm training programmes, however, participation rates for lone mothers of young children are substantially lower than for childless single women.

  9. Kiss my asterisk a feisty guide to punctuation and grammar

    CERN Document Server

    Baranick, Jenny

    2014-01-01

    Grammar has finally let its hair down! Unlike uptight grammar books that overwhelm us with every single grammar rule, Kiss My Asterisk is like a bikini: it's fun, flirty, and covers only the most important bits. Its lessons, which are 100 percent free of complicated grammar jargon, have been carefully selected to include today's most common, noticeable errors—the ones that confuse our readers or make them wonder if we are, in fact, smarter than a fifth grader. What is the proper use of an apostrophe? When should an ellipsis be used instead of an em dash? Why do we capitalize President Obama bu

  10. Countercurrent heat exchange and thermoregulation during blood-feeding in kissing bugs.

    Science.gov (United States)

    Lahondère, Chloé; Insausti, Teresita C; Paim, Rafaela Mm; Luan, Xiaojie; Belev, George; Pereira, Marcos H; Ianowski, Juan P; Lazzari, Claudio R

    2017-11-21

    Blood-sucking insects experience thermal stress at each feeding event on endothermic vertebrates. We used thermography to examine how kissing-bugs Rhodnius prolixus actively protect themselves from overheating. During feeding, these bugs sequester and dissipate the excess heat in their heads while maintaining an abdominal temperature close to ambient. We employed a functional-morphological approach, combining histology, µCT and X-ray-synchrotron imaging to shed light on the way these insects manage the flow of heat across their bodies. The close alignment of the circulatory and ingestion systems, as well as other morphological characteristics, support the existence of a countercurrent heat exchanger in the head of R. prolixus , which decreases the temperature of the ingested blood before it reaches the abdomen. This kind of system has never been described before in the head of an insect. For the first time, we show that countercurrent heat exchange is associated to thermoregulation during blood-feeding.

  11. Effect of a physical activity programme in the aquatic environment on haemodynamic constants in pregnant women.

    Science.gov (United States)

    Vázquez-Lara, Juana María; Ruiz-Frutos, Carlos; Rodríguez-Díaz, Luciano; Ramírez-Rodrigo, Jesús; Villaverde-Gutiérrez, Carmen; Torres-Luque, Gema

    2017-09-20

    To evaluate the effect of a physical activity programme in the aquatic environment with immersion up to the neck, of six weeks duration, on haemodynamic constants in pregnant women. A six-week physical activity programme in the aquatic environment was carried out with a total of 46 pregnant women, who were distributed into an experimental group (n = 18), which participated in the programme, and a control group (n = 28), which followed routine care. In both groups different haemodynamic measurements were evaluated before and after the program. At the beginning of the programme the mean systolic blood pressure was similar between groups, but diastolic blood pressure was slightly higher in the experimental group. When the measurements at the last session were compared, arterial pressures (systolic, diastolic and mean) were significantly higher in the control group (p <.050). Similarly, the initial plasma volume values did not differ between groups, but after the intervention, the control group women showed a higher mean (p <.010). The fraction of sodium excretion (FENa) increased significantly in the experimental group, after the programme, with a mean three times higher (p <.050). Aldosterone plasma levels did not show significant differences between the groups in the different measurements. A programme of swimming and immersion exercises in pregnant women contributes to hydrosaline balance, preventing an excessive increase in usual plasma volume during pregnancy and in the activity of the renin-aldosterone axis. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  12. Research programme 'Active Solar Energy Use - Solar Heating and Heat Storage'. Activities and projects 2003

    International Nuclear Information System (INIS)

    Hadorn, J.-C.; Renaud, P.

    2003-01-01

    In this report by the research, development and demonstration (RD+D) programme coordinators the objectives, activities and main results in the area of solar heating and heat storage in Switzerland are presented for 2003. In a stagnating market environment the strategy of the Swiss Federal Office of Energy mainly consists in improving the quality and durability of solar collectors and materials, optimizing combisystems for space heating and domestic hot water preparation, searching for storage systems with a higher energy storage density than in the case of sensible heat storage in water, developing coloured solar collectors for more architectonic freedom, and finalizing a seasonal heat storage project for 100 dwellings to demonstrate the feasibility of solar fractions larger than 50% in apartment houses. Support was granted to the Swiss Testing Facility SPF in Rapperswil as in previous years; SPF was the first European testing institute to perform solar collector labeling according to the new rules of the 'Solar Keymark', introduced in cooperation with the European Committee for Standardization CEN. Several 2003 projects were conducted within the framework of the Solar Heating and Cooling Programme of the International Energy Agency IEA. Computerized simulation tools were improved. With the aim of jointly producing high-temperature heat and electric power a solar installation including a concentrating collector and a thermodynamic machine based on a Rankine cycle is still being developed. Seasonal underground heat storage was studied in detail by means of a validated computer simulation programme. Design guidelines were obtained for such a storage used in the summer time for cooling and in the winter time for space heating via a heat pump: depending on the ratio 'summer cooling / winter heating', cooling requires a cooling machine, or direct cooling without such a machine is possible. The report ends up with the list of all supported RD+D projects

  13. KISS for STRAP: user extensions for a protein alignment editor.

    Science.gov (United States)

    Gille, Christoph; Lorenzen, Stephan; Michalsky, Elke; Frömmel, Cornelius

    2003-12-12

    The Structural Alignment Program STRAP is a comfortable comprehensive editor and analyzing tool for protein alignments. A wide range of functions related to protein sequences and protein structures are accessible with an intuitive graphical interface. Recent features include mapping of mutations and polymorphisms onto structures and production of high quality figures for publication. Here we address the general problem of multi-purpose program packages to keep up with the rapid development of bioinformatical methods and the demand for specific program functions. STRAP was remade implementing a novel design which aims at Keeping Interfaces in STRAP Simple (KISS). KISS renders STRAP extendable to bio-scientists as well as to bio-informaticians. Scientists with basic computer skills are capable of implementing statistical methods or embedding existing bioinformatical tools in STRAP themselves. For bio-informaticians STRAP may serve as an environment for rapid prototyping and testing of complex algorithms such as automatic alignment algorithms or phylogenetic methods. Further, STRAP can be applied as an interactive web applet to present data related to a particular protein family and as a teaching tool. JAVA-1.4 or higher. http://www.charite.de/bioinf/strap/

  14. Commentary: restarting NTD programme activities after the Ebola outbreak in Liberia.

    Science.gov (United States)

    Thomas, Brent C; Kollie, Karsor; Koudou, Benjamin; Mackenzie, Charles

    2017-05-01

    It is widely known that the recent Ebola Virus Disease (EVD) in West Africa caused a serious disruption to the national health system, with many of ongoing disease focused programmes, such as mass drug administration (MDA) for onchocerciasis (ONC), lymphatic filariasis (LF) and schistosomiasis (SCH), being suspended or scaled-down. As these MDA programmes attempt to restart post-EVD it is important to understand the challenges that may be encountered. This commentary addresses the opinions of the major health sectors involved, as well as those of community members, regarding logistic needs and challenges faced as these important public health programmes consider restarting. There appears to be a strong desire by the communities to resume NTD programme activities, although it is clear that some important challenges remain, the most prominent being those resulting from the severe loss of trained staff.

  15. IAEA activities related to research reactor fuel conversion and spent fuel return programmes

    International Nuclear Information System (INIS)

    Ritchie, I.G.; Adelfang, P.; Goldman, I.N.

    2004-01-01

    Full text: The IAEA has been involved for more than twenty years in supporting international nuclear non-proliferation efforts associated with reducing the amount of highly enriched uranium (HEU) in international commerce. IAEA projects and activities have directly supported the Reduced Enrichment for Research and Test Reactors (RERTR) programme, as well as directly associated efforts to return research reactor fuel to the country of origin where it was originally enriched. IAEA efforts have included the development and maintenance of several data bases with information related to research reactors and research reactor spent fuel inventories that have been essential in planning and managing both RERTR and spent fuel return programmes. Other IAEA regular budget programmes have supported research reactor fuel conversion from HEU to low enriched uranium, and in addressing issues common to many member states with spent fuel management problems and concerns. The paper briefly describes IAEA involvement since the early 1980's in these areas, including regular budget and Technical Co-operation programme activities, and focuses on efforts in the past five years to continue to support and accelerate U.S. and Russian research reactor spent fuel return programmes. It is hoped that an announcement of the extension of the U.S. Acceptance Programme, which is expected in the very near future, will facilitate the life extensions of many productive TRIGA reactors around the world. (author)

  16. Student Views on Assessment Activities: Perspectives from Their Experience on an Undergraduate Programme

    Science.gov (United States)

    Healy, Margaret; McCutcheon, Maeve; Doran, John

    2014-01-01

    Research on assessment activities has considered student responses to specific initiatives, but broader concerns underlying these responses have not been fully explored. Using a survey methodology, this paper explores how students view assessment activities, from the perspective of their experience on a four-year undergraduate programme,…

  17. [Physical activity programmes to reduce overweight and obesity in children and adolescents; a systematic review].

    Science.gov (United States)

    Aguilar Cordero, M J; Ortegón Piñero, A; Mur Vilar, N; Sánchez García, J C; García Verazaluce, J J; García García, I; Sánchez López, A M

    2014-10-01

    Obesity treatment has been the subject of much controversy; various authors have recommended the application of a comprehensive treatment programme, and in the light of this previous research, we consider the question of what is the most effective programme of physical activity to reduce overweight and obesity in children and adolescents. To analyse major studies on the effectiveness of physical activity in reducing overweight and obesity in children and adolescents. Systematic review of the results of physical activity programmes, published in scientific articles, to reduce overweight and obesity. Using an automated database search in PubMed and Google Scholar, conducted from October 2013 to March 2014, we identified 85 valid items. In selecting the items, the criteria applied included the usefulness and relevance of the subject matter and the credibility or experience of the research study authors. The internal and external validity of each of the articles reviewed was taken into account. This review confirmed the effectiveness of physical activity in reducing overweight and obesity in children and adolescents. The most effective programmes were those combining aerobic and anaerobic exercises. It is generally accepted that at least 180 minutes per week should be dedicated to exercise, in the form of three 60-minute sessions of moderate intensity. Such programmes could be sufficient for persons with overweight or obesity. Researchers in this field agree that when a diet based on an appropriate distribution of meals is combined with regular physical activity, they reinforce each other, and thus optimum results are obtained. Weight reduction programmes that take account of family involvement are more effective than nutrition education itself or other routine interventions that fail to consider family involvement. The role of pa rents and of the persons around the child or adolescent is essential to reinforce positive behaviour toward lifestyle change. Copyright AULA

  18. The radiation protection programme activities of the World Health Organization

    International Nuclear Information System (INIS)

    Komarov, E.; Suess, M.J.

    1980-01-01

    The radiation protection activities of the World Health Organization are reviewed. They include studies of radiation protection standards and guidelines, and public health aspects of nuclear power. WHO also provides member states with world data on radioactivity in air, water and food, and assessments of population exposure and health effects. (H.K.)

  19. Re-engaging Disaffected Youth through Physical Activity Programmes

    Science.gov (United States)

    Sandford, Rachel A.; Armour, Kathleen M.; Warmington, Paul C.

    2006-01-01

    It is a cherished belief within physical education and sport communities that participation in sport/physical activity has the potential to offer young people a range of physical, psychological and social benefits. More recently in the UK, this belief has become prominent in government policies that, among other things, are seeking to re-engage…

  20. Application of programme system BRAND for analysis of activation experiments

    International Nuclear Information System (INIS)

    Androsenko, A.A.; Androsenko, P.A.; Davletshin, A.N.; Tolstikov, V.A.

    1989-01-01

    Questions related to application of the BRAND program complex, simulating the processes of neutron radiation transfer by Monte Carlo method for analysing the results of measuring the cross sections by activation method, are considered. Results of calculating the corrections to neutron scattering in the air, in the activated sample, which are compared to results by other authors, are presented. The problem of choosing sufficient statistical accuracy of calculation results obtained is considered, choice criterion is proposed and grounded on the base of analysing the calculation results obtained. Questions related to possibilities of applying the complex when planning the forthcoming experiments, analysing experimental results, are discussed and the desired directions in extending the BRAND program complex capabilities are indicated as well. 8 refs.; 4 figs.; 1 tab

  1. An evaluation of Lincolnshire Sports’ ‘Workplace Challenge’ physical activity programme

    OpenAIRE

    Carter, Alice; Bishop, Daniel; Middleton, Geoff; Evans, Adam

    2014-01-01

    This report presents an evaluation of the Workplace Challenge, a County Sport Partnership led physical activity programme which utilises a website designed to engage people from workplaces in physical activity. The Workplace Challenge operated within the geographical boundary of Lincolnshire and thus targeted workplaces within this region. The overarching aim of the Workplace Challenge was to enact culture change within organisations in terms of employees’ physical activity habits. Metho...

  2. Utilisation of Wearable Computing for Space Programmes Test Activities Optimasation

    Science.gov (United States)

    Basso, V.; Lazzari, D.; Alemanni, M.

    2004-08-01

    New technologies are assuming a relevant importance in the Space business domain also in the Assembly Integration and Test (AIT) activities allowing process optimization and capability that were unthinkable only few years ago. This paper has the aim to describe Alenia Spazio (ALS) gained experience on the remote interaction techniques as a results of collaborations established both on European Communities (EC) initiatives, with Alenia Aeronautica (ALA) and Politecnico of Torino (POLITO). The H/W and S/W components performances increase and costs reduction due to the home computing massive utilization (especially demanded by the games business) together with the network technology possibility (offered by the web as well as the hi-speed links and the wireless communications) allow today to re-think the traditional AIT process activities in the light of the multimedia data exchange: graphical, voice video and by sure more in the future. Aerospace business confirm its innovation vocation which in the year '80 represents the cradle of the CAD systems and today is oriented to the 3D data visualization/ interaction technologies and remote visualisation/ interaction in collaborative way on a much more user friendly bases (i.e. not for specialists). Fig. 1 collects AIT extended scenario studied and adopted by ALS in these years. ALS experimented two possibilities of remote visualization/interaction: Portable [e.g. Fig.2 Personal Digital Assistant (PDA), Wearable] and walls (e.g.VR-Lab) screens as both 2D/3D visualisation and interaction devices which could support many types of traditional (mainly based on EGSE and PDM/CAD utilisation/reports) company internal AIT applications: 1. design review support 2. facility management 3. storage management 4. personnel training 5. integration sequences definition 6. assembly and test operations follow up 7. documentation review and external access to AIT activities for remote operations (e.g. tele-testing) EGSE Portable Clean room

  3. Biennial activity report of metallurgy programme for 1987 and 1988

    International Nuclear Information System (INIS)

    Shanmugam, V.; Rao, B.P.C.; Bhanu Sankara Rao, K.; Muralidharan, P.; Bhaduri, A.K.; Kuppusami, P.; Shyamsunder, M.T.; Sampath, N.; Sreedharan, O.M.

    1990-01-01

    The research and development (R and D) activities in the field of metallurgy at Indira Gandhi Centre for Atomic Research, Kalpakkam during 1987-1988 are reported in the form of individual summaries arranged under headings : (1) Mechanical Metallurgy Section, (2) Physical Metallurgy Section, (3) Chemical Metallurgy Section, (4) Materials Technology Section, (5) Division for PIE and NDT Development and (6) Quality Engineering Section. A list of publications by the staff scientists working in the field of metallurgy during report period is given in one of the appendices. (author). figs., tabs

  4. Oncogenic programmes and Notch activity: an 'organized crime'?

    Science.gov (United States)

    Dominguez, Maria

    2014-04-01

    The inappropriate Notch signalling can influence virtually all aspect of cancer, including tumour-cell growth, survival, apoptosis, angiogenesis, invasion and metastasis, although it does not do this alone. Hence, elucidating the partners of Notch that are active in cancer is now the focus of much intense research activity. The genetic toolkits available, coupled to the small size and short life of the fruit fly Drosophila melanogaster, makes this an inexpensive and effective animal model, suited to large-scale cancer gene discovery studies. The fly eye is not only a non-vital organ but its stereotyped size and disposition also means it is easy to screen for mutations that cause tumours and metastases and provides ample opportunities to test cancer theories and to unravel unanticipated nexus between Notch and other cancer genes, or to discover unforeseen Notch's partners in cancer. These studies suggest that Notch's oncogenic capacity is brought about not simply by increasing signal strength but through partnerships, whereby oncogenes gain more by cooperating than acting individually, as in a ring 'organized crime'. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Hydrogen activities in the European Union work-programme. Paper

    Energy Technology Data Exchange (ETDEWEB)

    Bahbout, A.; Tartaglia, G.P.; Buenger, U.

    2000-07-01

    Looking at some of the national and international developments in hydrogen technology it becomes clear which important contributions the hydrogen technology oriented activities of the EU have helped to prepare and trigger: (a) Transport Energy Strategy (TES): This initiative of 7 major German automobile and mineral oilcompanies is aimed at an industrial consensus on one or two gasoline alternative fuels, which are to be presented to the German Ministry of Transport. An intermediate trend is that hydrogen may become the fuel of choice. (b) BMW: The Bayerischen Motorenwerke have already very early exposed themselves to the vehicle and component development of hydrogen as a vehicle fuel, focussing on a strategy from CNG to LNG and LH{sub 2}. (c) Opel and GM: Opel has recently announced they have chosen hydrogen as the primary long term fuel for their fuel cell vehicles to be commercialized starting in 2004. (d) CFCP: The California Fuel Cell Partnership with partners from industry and politics has announced they are preparing the installation of hydrogen fuel stations aas well as 20-25 fuel cell buses and 30 passenger cars, mainly operated with hydrogen. (e) NEDO: The New Energy and Industrial Technology Development Organization (NEDO) of Japan has announced they are going to build hydrogen pilot refueling stations 18 months ahead of the original schedule to reduce the first-to-market-time. (f) Norway: A study group of Norwegian industry and institutes has carried out a comprehensive study for the Research Ministry on further R and D areas which should be intensified in a national strategy to be prepared for an international hydrogen energy system [SINTEF, 00]. (g) German Greens: The German ecologist party ''Greens'' has announced last week a shift from an anti-car lobbying to fostering greener cars, focussing on renewable hydrogen as a clean fuel. (h) Linde: The largest European Technical Gas Company has announced recently they will strategically

  6. ESA remote-sensing programme - Present activities and future plans

    Energy Technology Data Exchange (ETDEWEB)

    Plevin, J [ESA, Directorate of Planning and Future Programmes, Paris, France; Pryke, I [ESA, Directorate of Applications Programmes, Toulouse, France

    1979-02-01

    The present activities and future missions of the ESA program of spaceborne remote sensing of earth resources and environment are discussed. Program objectives have been determined to be the satisfaction of European regional needs by agricultural, land use, water resources, coastal and polar surveys, and meeting the requirements of developing nations in the areas of agricultural production, mineral exploration and disaster warning and assessment. The Earthnet system of data processing centers presently is used for the distribution of remote sensing data acquired by NASA satellites. Remote sensing experiments to be flown aboard Spacelab are the Metric Camera, to test high resolution mapping capabilities of a large format camera, and the Microwave Remote-Sensing Experiment, which operates as a two-frequency scatterometer, a synthetic aperture radar and a passive microwave radiometer. Studies carried out on the definition of future remote sensing satellite systems are described, including studies of system concepts for land applications and coastal monitoring satellites.

  7. Developing L2 Listening Fluency through Extended Listening-Focused Activities in an Extensive Listening Programme

    Science.gov (United States)

    Chang, Anna C-S.; Millett, Sonia

    2016-01-01

    This study investigates the effects on developing L2 listening fluency through doing extended listening-focused activities after reading and listening to audio graded readers. Seventy-six EFL university students read and listened to a total of 15 graded readers in a 15-week extensive listening programme. They were divided into three groups (Group…

  8. Effectiveness of a physical activity programme based on the Pilates method in pregnancy and labour.

    Science.gov (United States)

    Rodríguez-Díaz, Luciano; Ruiz-Frutos, Carlos; Vázquez-Lara, Juana María; Ramírez-Rodrigo, Jesús; Villaverde-Gutiérrez, Carmen; Torres-Luque, Gema

    To assess the effectiveness and safety of a physical activity programme based on use of the Pilates method, over eight weeks in pregnant women, on functional parameters, such as weight, blood pressure, strength, flexibility and spinal curvature, and on labour parameters, such as, type of delivery, episiotomy, analgesia and newborn weight. A randomized clinical trial was carried out on pregnant women, applying a programme of physical activity using the Pilates method, designed specifically for this population. A sample consisting of a total of 105 pregnant women was divided into two groups: intervention group (n=50) (32.87±4.46 years old) and control group (n=55) (31.52±4.95 years old). The intervention group followed a physical activity programme based on the Pilates method, for 2 weekly sessions, whereas the control group did not follow the program. Significant improvements (p<0.05) in blood pressure, hand grip strength, hamstring flexibility and spinal curvature, in addition to improvements during labour, decreasing the number of Caesareans and obstructed labour, episiotomies, analgesia and the weight of the newborns were found at the end of the intervention. A physical activity programme of 8 weeks based on the Pilates method improves functional parameters in pregnant women and benefits delivery. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  9. Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle: associated ligament and meniscal tears

    International Nuclear Information System (INIS)

    Hong, Hyun Pyo; Lee, Jae Gue; Park, Ji Seon; Ryu, Kyung Nam

    2004-01-01

    Kissing contusion between the posterolateral tibial plateau and lateral femoral condyle is frequently found in association with a tear of the anterior cruciate liagment (ACL). The purpose of this study was to determine which ligamentous and meniscal tears are associated with kissing contusion. We retrospectively reviewed the findings depicted by 323 consecutive MR images of the knee and confirmed at arthroscopy. For the diagnosis of disruption, ligaments, medial menisci (MM) and lateral menisci (LM) were evaluated using accepted criteria. We compared the prevalence and location of meniscal and ligamentous tears between group I (44 knees with kissing contusion) and group II (279 knees without kissing contusion). For statistical analysis the chi-square test was used. ACLs were torn in all 44 knees (100%) with kissing contusion, and 78 (28%) of 279 without kissing contusion. There were ten medial collateral ligament (MCL) tears (23%) in group I, and 17 MCL tears (6%), five lateral collateral ligament (LCL) tears (2%) and ten posterior cruciate ligament (PCL) tears (4%) in group II. In group I, meniscal tears were found in 22 MM (50%) and in 19 LM (43%), while in group II, they occurred in 128 MM (46%) and 128 LM (46%), In group I, 17 (77%) of 22 MM tears and 13 (68%) of 19 LM tears were located in the posterior horn, while in group II, the corresponding figures were 97/128 (76%) and 60 of 128 (47%). The differing prevalence of ACL and MCL tears between the groups was statistically significant (p 0.05). Although kissing contusion was a highly specific sign of ACL tears, its presence was also significant among MCL tears. There was no significant difference in meniscal tears with or without kissing contusion

  10. The EU research activities on partitioning and transmutation. From the 4. to the 5. framework programme

    International Nuclear Information System (INIS)

    Hugon, M.

    1999-01-01

    The European Commission is partly supporting research work on partitioning and transmutation of radioactive waste under the Fourth Framework Programme (1994-1998). This work includes nine research projects. Five strategy studies are evaluating the capabilities of various burners and fuel cycles to limit the production and even destroy the stock of actinides (plutonium and minor actinides). Two experimental projects are aiming at developing techniques for the chemical separation of actinides and two others are dealing with the investigation of transmutation of americium and long-lived fission products. The objectives of these studies are described together with the main results already obtained. The European Union should adopt the 5. Framework Programme (1998-2002) at the end of 1998. The broad lines of the research activities foreseen in partitioning and transmutation and future system under the 5. Framework Programme are briefly presented. (author)

  11. Evaluation of physical activity programmes for elderly people - a descriptive study using the EFQM' criteria

    Directory of Open Access Journals (Sweden)

    Santos Rute

    2011-02-01

    Full Text Available Abstract Background In the past years, there has been a growing concern in designing physical activity (PA programmes for elderly people, because evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Quality is an important issue when designing a PA programme for older people. Some studies support the Excellence Model of the European Foundation for Quality Management (EFQM as an operational framework for evaluating the quality of an organization. Within this context, the aim of this study was to characterize the quality management models of the PA programmes developed by Portuguese Local Administration to enhance quality of life for elderly people, according to the criteria of the EFQM Excellence Model. Methods A methodological triangulation was conducted in 26 PA programmes using questionnaire surveys, semi-structured interviews and document analysis. We used standard approaches to the statistical analysis of data including frequencies and percentages for the categorical data. Results Results showed that Processes (65,38%, Leadership (61,03%, Customer results (58,46 and People (51,28% had high percentage occurrences of quality practices. In contrast, Partnerships and resources (45,77%, People results (41,03%, Policy and strategy (37,91%, Key performance results (19,23% and Society results (19,23% had lower percentage occurrences. Conclusions Our findings suggest that although there are some good practices in PA programmes, there are still relevant areas that require improvement.

  12. A school-based physical activity program to improve health and fitness in children aged 6–13 years ("Kinder-Sportstudie KISS": study design of a randomized controlled trial [ISRCTN15360785

    Directory of Open Access Journals (Sweden)

    Knöpfli Martin

    2006-06-01

    Full Text Available Abstract Background Childhood obesity is the result of a long lasting imbalance between energy intake and energy expenditure. A major contributing factor is physical inactivity which is closely linked to bone health, cardiovascular disease risk, fitness and psychological factors. The school seems to provide an excellent setting to enhance levels of physical activity (PA. However, there is insufficient data from previous school-based intervention trials on how to enhance overall PA. It is also unknown whether an intervention aimed at increasing PA is effective in improving the children's health. The purpose of this paper is to outline the design of a school-based randomized, controlled trial (RCT aiming to increase overall PA and to improve fitness and health in 6- to 13-year-old children. Methods/Design 15 schools were randomized to the intervention (n = 9 or the control (n = 6 group, stratified by geographic region (urban vs. rural and by age (1st and 5th grade. Participation was given for all children in the intervention group since in this group the intervention was part of the normal school curriculum. The intervention during one academic year consisted of: 1. two additional physical education classes per week given by trained physical education teachers adding up to a total of five PA classes per week, 2. short PA breaks (2–5 min each during academic lessons, 3. PA home work, and 4. adaptation of recreational areas around the school. All children underwent anthropometric measurements, blood pressure assessment, fitness testing, measurement of PA and they filled out questionnaires. At least 70% of all children agreed to blood sampling and measurements of body composition and bone mineral measurements by dual energy x-ray absorptiometry. The primary endpoints of the study after one year were an increase in total PA by accelerometry, an increase in aerobic fitness measured by the 20 m shuttle run, a decrease in percent body fat derived from

  13. Active labour market programmes for women with a partner: Challenge or replication of traditional gender roles

    OpenAIRE

    Kopf, Eva; Zabel, Cordula

    2014-01-01

    A major unemployment and welfare benefit reform took place in Germany in 2005. One objective of this reform was to more strongly encourage an adult worker model of the family, with an emphasis on activating the formerly inactive. Our hypothesis is, however, that assignments to activation programmes, such as training or workfare, will in practice still tend to replicate patterns for the division of labour in the household that couples have become accustomed to. The views of case workers in emp...

  14. Sport activity and eating habits of people who were attending special obesity treatment programme.

    Science.gov (United States)

    Videmsek, Mateja; Stihec, Joze; Karpljuk, Damir; Starman, Anja

    2008-09-01

    The aims of the study were to analyse the sport activity and eating habits of obese people in their childhood and adulthood. The research was underpinned by a survey questionnaire containing 37 variables which was completed by 71 people attending the obesity programme. The frequencies and contingency tables were calculated, whereas statistical significance was established at a 5% significance level. The analysis of the results showed that more than one-half of the survey respondents joined the obesity programme primarily for reasons of health and well-being. Most obese people did not engage in any organised sport activity in their childhood, nor did most of their parents. The respondents practiced sport in their childhood to a greater extent if their parents were also physically active and if they guided and encouraged their children. No less than one-third of the respondents were overweight in their childhood, of whom two-thirds did not participate in any organised sport activity. The majority of the respondents (85.9%) are currently engaged in an organised sport activity in their adulthood, mainly due to their participation in the weight reduction programme; most of them practice sport twice a week. Their eating habits are encouraging; the share of skipped meals is considerably lower and practically negligible compared to that in childhood. It has to be emphasized that most of them are of opinion that obese people have difficulties finding expert information on obesity, nutrition and sport activities as well as weight management centers and institutions.

  15. Do children's health resources differ according to preschool physical activity programmes and parental behaviour? A mixed methods study.

    Science.gov (United States)

    Sterdt, Elena; Pape, Natalie; Kramer, Silke; Liersch, Sebastian; Urban, Michael; Werning, Rolf; Walter, Ulla

    2014-02-26

    Preschool can have positive effects on the development of a healthy lifestyle. The present study analysed to what extent different conditions, structures and behavioural models in preschool and family-children's central social microsystems-can lead to differences in children's health resources. Using a cross-sectional mixed methods approach, contrast analyses of "preschools with systematic physical activity programmes" versus "preschools without physical activity programmes" were conducted to assess the extent to which children's physical activity, quality of life and social behaviour differ between preschools with systematic and preschools without physical activity programmes. Differences in children's physical activity according to parental behaviour were likewise assessed. Data on child-related outcomes and parent-related factors were collected via parent questionnaires and child interviews. A qualitative focused ethnographic study was performed to obtain deeper insight into the quantitative survey data. Two hundred and twenty seven (227) children were interviewed at 21 preschools with systematic physical activity programmes, and 190 at 25 preschools without physical activity programmes. There was no significant difference in children's physical activity levels between the two preschool types (p = 0.709). However, the qualitative data showed differences in the design and quality of programmes to promote children's physical activity. Data triangulation revealed a strong influence of parental behaviour. The triangulation of methods provided comprehensive insight into the nature and extent of physical activity programmes in preschools and made it possible to capture the associations between systematic physical activity promotion and children's health resources in a differential manner.

  16. Positive messages enhance older adults' motivation and recognition memory for physical activity programmes.

    Science.gov (United States)

    Notthoff, Nanna; Klomp, Peter; Doerwald, Friederike; Scheibe, Susanne

    2016-09-01

    Although physical activity is an effective way to cope with ageing-related impairments, few older people are motivated to turn their sedentary lifestyle into an active one. Recent evidence suggests that walking can be more effectively promoted in older adults with positive messages about the benefits of walking than with negative messages about the risks of inactivity. This study examined motivation and memory as the supposed mechanisms underlying the greater effectiveness of positively framed compared to negatively framed messages for promoting activity. Older adults ( N  = 53, age 60-87 years) were introduced to six physical activity programmes that were randomly paired with either positively framed or negatively framed messages. Participants indicated how motivated they were to participate in each programme by providing ratings on attractiveness, suitability, capability and intention. They also completed surprise free recall and recognition tests. Respondents felt more motivated to participate in physical activity programmes paired with positively framed messages than in those with negatively framed ones. They also had better recognition memory for positively framed than negatively framed messages, and misremembered negatively framed messages to be positively framed. Findings support the notion that socioemotional selectivity theory-a theory of age-related changes in motivation-is a useful basis for health intervention design.

  17. Qualitative evaluation of a physical activity health promotion programme for people with intellectual disabilities in a group home setting.

    Science.gov (United States)

    Dixon-Ibarra, A; Driver, S; Nery-Hurwit, M; VanVolkenburg, H

    2018-01-01

    There is a lack of health promotion programming designed to change the physical activity environment of the group home setting. The Menu-Choice programme assists staff in creating physical activity goals alongside residents with intellectual disabilities and provides strategies to incorporate activity into the group home schedule. The purpose of this study was to complete a process evaluation of Menu-Choice utilizing qualitative methods. Twelve participants, who completed a 10-week pilot intervention (n = 7 staff, mean age 42; n = 5 residents, mean age 52), participated in face-to-face interviews. Participants represented five group home sites involved in the intervention. Meta-themes included: (i) Programme training, (ii) Programme implementation, (iii) Programme physical activity, (iv) Programme barriers, (v) Programme facilitators and (vi) Programme feedback. Changes in programme training and simplified programme materials are needed to accommodate identified barriers for implementation. The importance of obtaining increased agency support and policy change is highlighted. © 2017 John Wiley & Sons Ltd.

  18. Waste management assessment and technical review programme. WATRP. An international peer review service for radioactive waste management activities

    International Nuclear Information System (INIS)

    1994-09-01

    International Atomic Energy Agency provides international peer review services in radioactive waste management to those Member States that have established radioactive waste management programmes. Such services are provided within Waste Management Assessment and Technical Review Programme (WATRP). The main objective of WATRP is to provide international expertise and information on a requested subject in the field of radioactive waste management and to validate that programmes and activities are sound and performing well. Refs, figs and tabs

  19. Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period.

    Directory of Open Access Journals (Sweden)

    Xiaoliang Qiu

    Full Text Available Reproduction requires adequate energy stores for parents and offspring to survive. Kiss1 neurons, which are essential for fertility, have the potential to serve as the central sensors of metabolic factors that signal to the reproductive axis the presence of stored calories. Paradoxically, obesity is often accompanied by infertility. Despite excess circulating levels of insulin and leptin, obese individuals exhibit resistance to both metabolic factors in many neuron types. Thus, resistance to insulin or leptin in Kiss1 neurons could lead to infertility. Single deletion of the receptors for either insulin or the adipokine leptin from Kiss1 neurons does not impair adult reproductive dysfunction. However, insulin and leptin signaling pathways may interact in such a way as to obscure their individual functions. We hypothesized that in the presence of genetic or obesity-induced concurrent insulin and leptin resistance, Kiss1 neurons would be unable to maintain reproductive function. We therefore induced a chronic hyperinsulinemic and hyperleptinemic state in mice lacking insulin receptors in Kiss1 neurons through high fat feeding and examined the impact on fertility. In an additional, genetic model, we ablated both leptin and insulin signaling in Kiss1 neurons (IR/LepRKiss mice. Counter to our hypothesis, we found that the addition of leptin insensitivity did not alter the reproductive phenotype of IRKiss mice. We also found that weight gain, body composition, glucose and insulin tolerance were normal in mice of both genders. Nonetheless, leptin and insulin receptor deletion altered pubertal timing as well as LH and FSH levels in mid-puberty in a reciprocal manner. Our results confirm that Kiss1 neurons do not directly mediate the critical role that insulin and leptin play in reproduction. However, during puberty kisspeptin neurons may experience a critical window of susceptibility to the influence of metabolic factors that can modify the onset of

  20. Peaceful nuclear programme and front end nuclear fuel cycle activities in Pakistan

    International Nuclear Information System (INIS)

    S. Mukhtar Ahmed

    1999-01-01

    Pakistan has a modest but broad based nuclear programme related to peaceful uses of atomic energy in nuclear power, agriculture, medicine and industry. While development projects in these areas form the major segment of Pakistan Atomic Energy Commission's work, complimentary activities in basic research and human resource development are also supported. PAEC through its activities has been moving towards the goal of achieving self-reliance for its existing programme in an international atmosphere of embargoes and restrictions and in pursuit of creating an infrastructure to help sustain an indigenous nuclear power programme. To solve the local needs and requirements, radioisotopes and nuclear techniques have been applied in agriculture, medicine, hydrology and industry. PAEC has one large research and development establishment in physical sciences, three R and D centers in agriculture, one in biotechnology, and ten nuclear medical centers for diagnostics and oncology treatment. Two research reactors form nucleus of research and development activities in nuclear sciences. In the power sector a 137 Mew CANDU power reactor is in operation in Karachi since 1971. Another 300 Mew PWR is under construction and is nearing completion. Front-end fuel cycle and engineering infrastructure facilities have been established to support continued operation of Karachi Nuclear Power Plant (KANUPP). To support the engineering activities it has established facilities for precision workshops, non-destructive testing center and a welding institute. (author)

  1. Corporate sponsorship of physical activity promotion programmes: part of the solution or part of the problem?

    Science.gov (United States)

    Jane, B; Gibson, K

    2017-06-07

    Parklives is a programme intended to raise levels of physical activity across the UK, funded by Coca-Cola GB and delivered in association with Local Authorities and other organizations. Such public-private partnerships have been advocated by many however critics suggest that the conflict between stakeholder motives is too great. This study conducted a content analysis of twitter content related to the ParkLives physical activity programme. Images and text were analysed from two separate weeks, one from the school vacation period and one during school term time. Three hundred and eighteen tweets were analysed. Content analysis revealed 79% of images contained children and 45% of these images contained prominent Coca-Cola branding, a level of exposure that suggests ParkLives simultaneously provides opportunities for children's physical activity and for targeted marketing. Content analysis also demonstrated that the programme allowed increased access to policy-makers. The sponsorship of a physical activity promotion campaign can allow a corporation to target its marketing at children and gain access to health-related policy development networks. This study reinforces the need for independent evaluation of all potential impacts of such a partnership and calls on those responsible for community health to fully consider the ethical implications of such relationships. © The Author 2017. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  2. Clinical outcomes after final kissing balloon inflation compared with no final kissing balloon inflation in bifurcation lesions treated with a dedicated coronary bifurcation stent

    NARCIS (Netherlands)

    Grundeken, Maik J.; Lesiak, Maciej; Asgedom, Solomon; Garcia, Eulogio; Bethencourt, Armando; Norell, Michael S.; Damman, Peter; Woudstra, Pier; Koch, Karel T.; Vis, M. Marije; Henriques, Jose P.; Tijssen, Jan G.; Onuma, Yoshinobu; Foley, David P.; Bartorelli, Antonio L.; Stella, Pieter R.; de Winter, Robbert J.; Wykrzykowska, Joanna J.

    2014-01-01

    We evaluated differences in clinical outcomes between patients who underwent final kissing balloon inflation (FKBI) and patients who did not undergo FKBI in bifurcation treatment using the Tryton Side Branch Stent (Tryton Medical, Durham, North Carolina, USA). Clinical outcomes were defined as

  3. Clinical outcomes after final kissing balloon inflation compared with no final kissing balloon inflation in bifurcation lesions treated with a dedicated coronary bifurcation stent

    NARCIS (Netherlands)

    M.J. Grundeken (Maik); M. Lesiak (MacIej); S. Asgedom (Solomon); E. Garcia (Eulogio); A. Bethencourt (Armando); M.S. Norell (Michael); K. Damman (Kevin); E. Woudstra (Evert); K. Koch (Karel); M.M. Vis (Marije); J.P.S. Henriques (Jose); J.G.P. Tijssen (Jan); Y. Onuma (Yoshinobu); D.P. Foley (David); A. Bartorelli (Antonio); P.R. Stella (Pieter); R.J. de Winter (Robbert); J.J. Wykrzykowska (Joanna)

    2014-01-01

    textabstractObjective We evaluated differences in clinical outcomes between patients who underwent final kissing balloon inflation (FKBI) and patients who did not undergo FKBI in bifurcation treatment using the Tryton Side Branch Stent (Tryton Medical, Durham, North Carolina, USA). Methods Clinical

  4. Programme of Preparatory Activities on Launching First Nuclear Power Plant in Croatia

    International Nuclear Information System (INIS)

    Jakic, I.; Lebegner, J.; Perovic, N.

    2010-01-01

    New Croatian energy policy recognizes nuclear energy as solution for rising needs for energy and, thus, opens the possibility to construct first nuclear power plant in Croatia. Within this frame, the Croatian government is developing an implementation programme according to this policy and preparing basis for making decision about construction of nuclear power plant. Croatian parliament is responsible for this decision which is expected by the end of 2012. During this period, stake holders in this project (government, regulatory body and future operator of the plant) have to complete activities of preparatory phase of Croatian Nuclear Energy Programme (CRONEP) project according to methodology recommended by IAEA (International Atomic Energy Agency). This paper defines these activities and estimate the costs of first, preparatory phase based on previous experience of other countries which finished the phase successfully. Also, it describes the potential role of Croatian utility as stake holder due to its experience as co-owner of Nuclear power plant Krsko.(author).

  5. Two families with normosmic congenital hypogonadotropic hypogonadism and biallelic mutations in KISS1R (KISS1 receptor: clinical evaluation and molecular characterization of a novel mutation.

    Directory of Open Access Journals (Sweden)

    Frédéric Brioude

    Full Text Available CONTEXT: KISS1R mutations have been reported in few patients with normosmic congenital hypogonadotropic hypogonadism (nCHH (OMIM #146110. OBJECTIVE: To describe in detail nCHH patients with biallelic KISS1R mutations belonging to 2 unrelated families, and to functionally characterize a novel KISS1R mutation. RESULTS: An original mutant, p.Tyr313His, was found in the homozygous state in 3 affected kindred (2 females and 1 male from a consanguineous Portuguese family. This mutation, located in the seventh transmembrane domain, affects a highly conserved amino acid, perturbs the conformation of the transmembrane segment, and impairs MAP kinase signaling and intracellular calcium release. In the second family, a French Caucasian male patient with nCHH was found to carry two recurrent mutations in the compound heterozygous state (p.Leu102Pro/Stop399Arg. In this man, pulsatile GnRH (Gonadotropin Releasing Hormone administration restored pulsatile LH (Luteinizing Hormone secretion and testicular hormone secretion. Later, long-term combined gonadotropin therapy induced spermatogenesis, enabling 3 successive pregnancies that resulted in 2 miscarriages and the birth of a healthy boy. CONCLUSION: We show that a novel loss-of-function mutation (p.Tyr313His in the KISS1R gene can cause familial nCHH, revealing the crucial role of this amino acid in KISS1R function. The observed restoration of gonadotropin secretion by exogenous GnRH administration further supports, in humans, the hypothalamic origin of the gonadotropin deficiency in this genetic form of nCHH.

  6. New and recently finalised activities within the NKS Programmes for Nordic cooperation on nuclear reactor safety and emergency preparedness

    DEFF Research Database (Denmark)

    Andgren, Karin; Andersson, Kasper Grann; Magnússon, Sigurður M.

    2015-01-01

    Over the years, NKS has provided funding for hundreds of research activities in fields comprising reactor safety, decommissioning, nuclear and radiological emergency preparedness, and management of radioactive waste. Advanced technologies and methods developed under the NKS framework have been used...... within the Nordic countries as well as internationally. Two programme areas are defined under the NKS platform: The NKS-R programme on nuclear reactor safety and the NKS-B programme on emergency preparedness. Three articles, giving an introduction to NKS and its two programmes, were published...

  7. Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor.

    Science.gov (United States)

    Lievens, Sam; Gerlo, Sarah; Lemmens, Irma; De Clercq, Dries J H; Risseeuw, Martijn D P; Vanderroost, Nele; De Smet, Anne-Sophie; Ruyssinck, Elien; Chevet, Eric; Van Calenbergh, Serge; Tavernier, Jan

    2014-12-01

    Probably every cellular process is governed by protein-protein interaction (PPIs), which are often highly dynamic in nature being modulated by in- or external stimuli. Here we present KISS, for KInase Substrate Sensor, a mammalian two-hybrid approach designed to map intracellular PPIs and some of the dynamic features they exhibit. Benchmarking experiments indicate that in terms of sensitivity and specificity KISS is on par with other binary protein interaction technologies while being complementary with regard to the subset of PPIs it is able to detect. We used KISS to evaluate interactions between different types of proteins, including transmembrane proteins, expressed at their native subcellular location. In situ analysis of endoplasmic reticulum stress-induced clustering of the endoplasmic reticulum stress sensor ERN1 and ligand-dependent β-arrestin recruitment to GPCRs illustrated the method's potential to study functional PPI modulation in complex cellular processes. Exploring its use as a tool for in cell evaluation of pharmacological interference with PPIs, we showed that reported effects of known GPCR antagonists and PPI inhibitors are properly recapitulated. In a three-hybrid setup, KISS was able to map interactions between small molecules and proteins. Taken together, we established KISS as a sensitive approach for in situ analysis of protein interactions and their modulation in a changing cellular context or in response to pharmacological challenges. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  8. Maternal kisses are not effective in alleviating minor childhood injuries (boo-boos): a randomized, controlled and blinded study.

    Science.gov (United States)

    2015-12-01

    The practice of maternal kissing of minor injuries of childhood (boo-boos), though widely endorsed and practised, has never been demonstrated to be of benefit to children. To determine the efficacy, if any, of maternal kissing of boo-boos in toddlers. Randomized, controlled and double-blinded study of children with experimentally induced minor injuries. Control arms included both no intervention group and 'sham' (non-maternal) kissing. Children were blinded to the identity of the kisser in both the maternal and sham control groups. Outpatient research clinics in Ottawa, Canada. 943 maternal-toddler pairs recruited from the community. Toddler Discomfort Index (TDI) pre-injury, 1 and 5 minutes post-injury. One-minute and 5-minute TDI scores did not differ significantly between the maternal and sham kiss groups. Both of these groups had significantly higher TDI scores at 5 minutes compared to the no intervention group. Maternal kissing of boo-boos confers no benefit on children with minor traumatic injuries compared to both no intervention and sham kissing. In fact, children in the maternal kissing group were significantly more distressed at 5 minutes than were children in the no intervention group. The practice of maternal kissing of boo-boos is not supported by the evidence and we recommend a moratorium on the practice. © 2015 John Wiley & Sons, Ltd.

  9. RPII Inspection and Licensing Activities and Annual Inspection Programme for 2013

    International Nuclear Information System (INIS)

    2013-04-01

    The objective of this report is to provide an overview of inspection activities of the Radiological Protection Institute of Ireland RPII, to examine the evolution in licensee numbers and to outline the rationale in developing annual inspection programmes. All inspection activities are now carried out within the framework of a quality management system including inspection planning, the training of inspectors, the conduct of inspections as well as post inspection follow up and review. This report also provides an overview of the main features of the quality system

  10. RPII Inspection and Licensing Activities and Annual Inspection Programme for 2011

    International Nuclear Information System (INIS)

    2010-07-01

    The objective of this report is to provide an overview of inspection activities of the Radiological Protection Institute of Ireland, to examine the evolution in licensee numbers and to outline the rationale in developing annual inspection programmes. All inspection activities are now carried out within the framework of a quality management system including: inspection planning, the training of inspectors, the conduct of inspections as well as inspection follow up and review. The report also provides an overview of the main features of the quality system

  11. Effects of a physical activity programme on body perception and composition in overweight adolescents

    Directory of Open Access Journals (Sweden)

    Onofre Ricardo Contreras-Jordán

    2017-03-01

    Full Text Available Background The purpose of this study was to examine the effectiveness of a six months' physical activity programme for overweight and obese adolescents, in order to improve the perception of their own body image and composition between two groups of adolescents, and to check possible gender differences. Aims The aim is to improve the body perception and composition in overweight adolescents with a physical activity programme. Methods It was a quasi-experimental design, with a control group and intervention group. Measures of pre-test and post-test were taken. A total of 38 adolescents that belong to the first cycle of Compulsory Secondary aged 12–15, with a body mass index (BMI higher than the 85th percentile according to the WHO (World Health Organization, participated in the intervention. The anthropometric variables, height, weight, BMI, body fat percentage, and the circumference of the waist, hip, arm and medial calf, were measured pre- and post-treatment. The body image perception was measured using the Gardner test. The experimental group participated in the physical activity programme for a six months period. The physical activity intervention consisted of three sessions of 90 minutes each week in a sports centre. The structure of the sessions consisted of a warm-up (5–10 minutes, a main activity (60–70 minutes, combineding strength and cardiovascular training and a cool-down (7–10 minutes. Results After physical activity intervention the results showed significant improvements in the experimental group compared to the control group in the circumference of the waist, the hip, the arm, the medial calf (p<0.01 and as well as the fat percentage, the percentage of muscle mass (p<0.05. The results showed how the body image distortion presented a significant and negative correlation with the circumference of the waist (p<0.001, of the hips (p<0.01, and of the arm (p<0.001, differences were observed between gender. Conclusion Our study

  12. [Effect of a physical activity programme in patients with fibromyalgia: a systematic review].

    Science.gov (United States)

    Cadenas-Sánchez, Cristina; Ruiz-Ruiz, Jonatan

    2014-12-23

    The aim of this review was to determine what type of physical activity programmes have been developed in patients with fibromyalgia and what are its effects and benefits on the degree of pain and quality of life. The search was performed in MEDLINE, Web of Science and SPORTDiscus databases. The word "fibromyalgia" was always used as a criterion for combined search (using "AND" connector) with physical activity, exercise, physical therapy and training (MeSH terms). Of the 2,531 initial results, 33 papers were selected for review. The studies reviewed focus primarily on dance activities, water activities, multidisciplinary, mind-body work, fitness and stretching. After applying the intervention program, the pain level was reduced between 10 and 44.2%, and the impact of the disease between 5.3 and 17.9%, improving the symptoms of these patients. In conclusion, a multidisciplinary programme (in which physical activity is included) may have positive effects on the quality of life of people with fibromyalgia. Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  13. Objects prompt authentic scientific activities among learners in a museum programme

    DEFF Research Database (Denmark)

    Achiam, Marianne; Simony, Leonora; Lindow, Bent Erik Kramer

    2016-01-01

    Although the scientific disciplines conduct practical work in different ways, all consider practical work as the essential way of connecting objects and phenomena with ideas and the abstract. Accordingly, practical work is regarded as central to science education as well. We investigate a practical......, object-based palaeontology programme at a natural history museum to identify how palaeontological objects prompt scientific activity among upper secondary school students. We first construct a theoretical framework based on an analysis of the programme’s palaeontological content. From this, we build our...

  14. RPII Inspection and Licensing Activities and Annual Inspection Programme for 2012

    International Nuclear Information System (INIS)

    2012-04-01

    The purpose of this document is to promote transparency in the activities of the RPII. It explains aspects of the internal workings of the Regulation and Information Management Division of the Institute to aid understanding of the processes and decisions of that Division which may impact on licensees and other interested parties. The objective of the report is to provide an overview of inspection activities of the RPII, to examine the evolution in licensee numbers and to outline the rationale in developing annual inspection programmes. All inspection activities are now carried out within the framework of a quality management system including; inspection planning, the training of inspectors, the conduct of inspections, as well as post inspection follow up and review. This report also provides an overview of the main features of the quality system

  15. NDA generic research programme for higher activity waste management issues - 16390

    International Nuclear Information System (INIS)

    McKinney, James; Brownridge, Melanie

    2009-01-01

    NDA has a responsibility to ensure decommissioning activities are sufficiently technically underpinned and appropriate Research and Development (Rand D) is carried out. The NDA funds research and development (R and D) indirectly via the Site Licence Companies (SLCs) or directly. The main component of directly funded R and D is the NDA Direct Research Portfolio (DRP). The DRP is split into four framework areas: - University Interactions; - Waste Processing; - Material Characterisation; - Actinide and Strategic Nuclear Materials. These four framework areas were competed through an Official Journal of European Union (OJEU) process in 2008. Although all four areas involve waste management, Waste Processing and Material Characterisation specifically deal with Higher Activity Waste (HAW) waste management issues. The Waste Processing area was awarded to three groups: (i) National Nuclear Laboratory (NNL), (ii) Consortium led by Hyder Consulting Ltd, and (iii) Consortium led by UKAEA Ltd. The Material Characterisation area was awarded to three groups: (i) NNL, (ii) Serco, and (iii) Consortium led by UKAEA Ltd. The initial work in Waste Processing and Material Characterisation was centered on establishing a forward research programme to address the generic needs of the UK civil nuclear industry and the NDA strategic drivers for waste management and land quality. This has been achieved by the four main framework contractors from the Waste Processing and Materials Characterisation areas working together with the NDA to identify the key research themes and begin the development of the NDA's HAW Management Research Programme. The process also involves active engagement with both industry and regulators via the Nuclear Waste Research Forum (NWRF). The NDA's HAW Management Research Programme includes a number of themes: - Optimisation of Interim Store Operation and Design; - Alternative Waste Encapsulants; - Waste Package Integrity; - Alternative Waste treatment methods

  16. Activities of the Sofia EC Energy Center in the framework of the THERMIE programme

    International Nuclear Information System (INIS)

    Latinski, K.

    1993-01-01

    The European Community Energy Center in Sofia is responsible for the EC implementation of the THERMIE programme. The programme's activities are promotion and dissemination of existing European technologies leading to better energy management and covering the fields of rational use of hydrocarbons, solid fuels and renewable energy sources. Application of these technologies would lead to substantial energy savings resulting in significant financial and environmental benefits. During its one-year operation the EC Energy Centre has organized and performed specific action as energy audits (food and beverage industrial units and buildings), demonstration projects (local heating control in buildings, diesel engine regulation of buses), training courses and seminars (in energy management and in space heating measuring and regulation), workshops (energy conservation in buildings, the bricks and clays sector and the food and beverage sector) and studies (wind energy potential, 'clean' coal technologies potential). Some of these actions have had very encouraging results showing potential energy savings of the order of 10-20% just by application of simple measures and with small additional investment. The activities of the EC Energy Centre in the coming year aimed at electricity savings along the entire line of electricity generation, transmission and consumption are outlined. (author)

  17. Qualitative Evaluation of a Physical Activity Health Promotion Programme for People with Intellectual Disabilities in a Group Home Setting

    Science.gov (United States)

    Dixon-Ibarra, A.; Driver, S.; Nery-Hurwit, M.; VanVolkenburg, H.

    2018-01-01

    Background: There is a lack of health promotion programming designed to change the physical activity environment of the group home setting. The Menu-Choice programme assists staff in creating physical activity goals alongside residents with intellectual disabilities and provides strategies to incorporate activity into the group home schedule. The…

  18. Missed opportunities in the evaluation of public health interventions: a case study of physical activity programmes

    Directory of Open Access Journals (Sweden)

    Sarah Hanson

    2017-08-01

    Full Text Available Abstract Background Evidence-based approaches are requisite in evaluating public health programmes. Nowhere are they more necessary than physical activity interventions where evidence of effectiveness is often poor, especially within hard to reach groups. Our study reports on the quality of the evaluation of a government funded walking programme in five ‘Walking Cities’ in England. Cities were required to undertake a simple but robust evaluation using the Standard Evaluation Framework (SEF for physical activity interventions to enable high quality, consistent evaluation. Our aim was not to evaluate the outcomes of this programme but to evaluate whether the evaluation process had been effective in generating new and reliable evidence on intervention design and what had worked in ‘real world’ circumstances. Methods Funding applications and final reports produced by the funder and the five walking cities were obtained. These totalled 16 documents which were systematically analysed against the 52 criteria in the SEF. Data were cross checked between the documents at the bid and reporting stage with reference to the SEF guidance notes. Results Generally, the SEF reporting requirements were not followed well. The rationale for the interventions was badly described, the target population was not precisely specified, and neither was the method of recruitment. Demographics of individual participants, including socio-economic status were reported poorly, despite being a key criterion for funding. Conclusions Our study of the evaluations demonstrated a missed opportunity to confidently establish what worked and what did not work in walking programmes with particular populations. This limited the potential for evidence synthesis and to highlight innovative practice warranting further investigation. Our findings suggest a mandate for evaluability assessment. Used at the planning stage this may have ensured the development of realistic objectives and

  19. Expression of preoperative KISS1 gene in tumor tissue with epithelial ovarian cancer and its prognostic value.

    Science.gov (United States)

    Cao, Fang; Chen, Liping; Liu, Manhua; Lin, Weiwei; Ji, Jinlong; You, Jun; Qiao, Fenghai; Liu, Hongbin

    2016-11-01

    Our study aimed to elucidate the role of Kisspeptin (KISS1) in tumor tissues of patients with epithelial ovarian cancer (EOC) and investigate the prognostic value of this biomarker.Forty EOC patients and 20 uterine fibroids female patients with healthy ovaries undergoing cytoreductive surgery between January 2010 and January 2014 in our hospital were enrolled in this study. KISS1 expression in tumor and normal tissues was detected. Correlations between clinic-pathologic variables and KISS1 expression in EOC tissues and the prognostic value of KISS1 for overall survival were evaluated.During the follow-up of 11.2 to 62.1 months, the overall survival rate and mean survival time were 28.9% (11/38) and 38.35 ± 2.84 months. Preoperative KISS1 mRNA was higher in tumor tissue than in normal tissue (P <0.001), and it was associated with histologic grade of tumor, surgical FIGO stage, metastasis, and residual tumor size (all P <0.05). Multivariate survival analysis indicated significant influence of residual tumor size (HR = 2.357, P = 0.039) and preoperative KISS1 mRNA (HR = 0.0001, P <0.001) on mean survival time. Patients with low KISS1 mRNA expression had shorter survival time than those with high expression (P = 0.001).Preoperative KISS1 mRNA was a potential prognostic biomarker for EOC, and high preoperative KISS1 expression indicated a favorable prognosis.

  20. Melt With This Kiss: Paralyzing and Liquefying Venom of The Assassin Bug Pristhesancus plagipennis (Hemiptera: Reduviidae).

    Science.gov (United States)

    Walker, Andrew A; Madio, Bruno; Jin, Jiayi; Undheim, Eivind A B; Fry, Bryan G; King, Glenn F

    2017-04-01

    Assassin bugs (Hemiptera: Heteroptera: Reduviidae) are venomous insects, most of which prey on invertebrates. Assassin bug venom has features in common with venoms from other animals, such as paralyzing and lethal activity when injected, and a molecular composition that includes disulfide-rich peptide neurotoxins. Uniquely, this venom also has strong liquefying activity that has been hypothesized to facilitate feeding through the narrow channel of the proboscis-a structure inherited from sap- and phloem-feeding phytophagous hemipterans and adapted during the evolution of Heteroptera into a fang and feeding structure. However, further understanding of the function of assassin bug venom is impeded by the lack of proteomic studies detailing its molecular composition.By using a combined transcriptomic/proteomic approach, we show that the venom proteome of the harpactorine assassin bug Pristhesancus plagipennis includes a complex suite of >100 proteins comprising disulfide-rich peptides, CUB domain proteins, cystatins, putative cytolytic toxins, triabin-like protein, odorant-binding protein, S1 proteases, catabolic enzymes, putative nutrient-binding proteins, plus eight families of proteins without homology to characterized proteins. S1 proteases, CUB domain proteins, putative cytolytic toxins, and other novel proteins in the 10-16-kDa mass range, were the most abundant venom components. Thus, in addition to putative neurotoxins, assassin bug venom includes a high proportion of enzymatic and cytolytic venom components likely to be well suited to tissue liquefaction. Our results also provide insight into the trophic switch to blood-feeding by the kissing bugs (Reduviidae: Triatominae). Although some protein families such as triabins occur in the venoms of both predaceous and blood-feeding reduviids, the composition of venoms produced by these two groups is revealed to differ markedly. These results provide insights into the venom evolution in the insect suborder

  1. Status on the Finnish activities regarding qualification of programmable automation systems

    International Nuclear Information System (INIS)

    Juslin, K.

    1995-01-01

    The research work on qualification of programmable automation system is described which describe the development of methods, tools and practices for the evaluation and licensing of safety critical programmable automation systems. 26 refs

  2. Motor programme activating therapy influences adaptive brain functions in multiple sclerosis: clinical and MRI study.

    Science.gov (United States)

    Rasova, Kamila; Prochazkova, Marie; Tintera, Jaroslav; Ibrahim, Ibrahim; Zimova, Denisa; Stetkarova, Ivana

    2015-03-01

    There is still little scientific evidence for the efficacy of neurofacilitation approaches and their possible influence on brain plasticity and adaptability. In this study, the outcome of a new kind of neurofacilitation approach, motor programme activating therapy (MPAT), was evaluated on the basis of a set of clinical functions and with MRI. Eighteen patients were examined four times with standardized clinical tests and diffusion tensor imaging to monitor changes without therapy, immediately after therapy and 1 month after therapy. Moreover, the strength of effective connectivity was analysed before and after therapy. Patients underwent a 1-h session of MPAT twice a week for 2 months. The data were analysed by nonparametric tests of association and were subsequently statistically evaluated. The therapy led to significant improvement in clinical functions, significant increment of fractional anisotropy and significant decrement of mean diffusivity, and decrement of effective connectivity at supplementary motor areas was observed immediately after the therapy. Changes in clinical functions and diffusion tensor images persisted 1 month after completing the programme. No statistically significant changes in clinical functions and no differences in MRI-diffusion tensor images were observed without physiotherapy. Positive immediate and long-term effects of MPAT on clinical and brain functions, as well as brain microstructure, were confirmed.

  3. Effects of a physical activity programme in the school setting on physical fitness in preschool children.

    Science.gov (United States)

    Latorre-Román, P A; Mora-López, D; García-Pinillos, F

    2018-05-01

    The purpose of this study was to examine the effects of a 10-week aerobic games programme on physical fitness. One hundred eleven children, aged 3 to 6 years, participated in this study; 60 children were male (age: 4.28 ± 0.61 years old), and 51 were female (age 4.59 ± 0.49 years old). Participants were randomly assigned to an experimental group (EG; n = 56) and a control group (CG; n = 55). A fitness test battery previously validated for preschoolers was used. The children in the EG performed 3 weekly training sessions of physical activity in a classroom during a 10-week period. Every EG session lasted about 30 min. There were no significant differences in any variable in the pretest between groups. In the posttest, the EG achieved better results in horizontal jump and sprint. In relation to posttest-pretest differences, the EG showed a greater increase in horizontal jump, sprint, and endurance. An aerobic games programme in the school setting improved physical fitness in preschool children. © 2018 John Wiley & Sons Ltd.

  4. Erythroid cell mitochondria receive endosomal iron by a "kiss-and-run" mechanism.

    Science.gov (United States)

    Hamdi, Amel; Roshan, Tariq M; Kahawita, Tanya M; Mason, Anne B; Sheftel, Alex D; Ponka, Prem

    2016-12-01

    In erythroid cells, more than 90% of transferrin-derived iron enters mitochondria where ferrochelatase inserts Fe 2+ into protoporphyrin IX. However, the path of iron from endosomes to mitochondrial ferrochelatase remains elusive. The prevailing opinion is that, after its export from endosomes, the redox-active metal spreads into the cytosol and mysteriously finds its way into mitochondria through passive diffusion. In contrast, this study supports the hypothesis that the highly efficient transport of iron toward ferrochelatase in erythroid cells requires a direct interaction between transferrin-endosomes and mitochondria (the "kiss-and-run" hypothesis). Using a novel method (flow sub-cytometry), we analyze lysates of reticulocytes after labeling these organelles with different fluorophores. We have identified a double-labeled population definitively representing endosomes interacting with mitochondria, as demonstrated by confocal microscopy. Moreover, we conclude that this endosome-mitochondrion association is reversible, since a "chase" with unlabeled holotransferrin causes a time-dependent decrease in the size of the double-labeled population. Importantly, the dissociation of endosomes from mitochondria does not occur in the absence of holotransferrin. Additionally, mutated recombinant holotransferrin, that cannot release iron, significantly decreases the uptake of 59 Fe by reticulocytes and diminishes 59 Fe incorporation into heme. This suggests that endosomes, which are unable to provide iron to mitochondria, cause a "traffic jam" leading to decreased endocytosis of holotransferrin. Altogether, our results suggest that a molecular mechanism exists to coordinate the iron status of endosomal transferrin with its trafficking. Besides its contribution to the field of iron metabolism, this study provides evidence for a new intracellular trafficking pathway of organelles. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Mass-casualty Response to the Kiss Nightclub in Santa Maria, Brazil.

    Science.gov (United States)

    Dal Ponte, Silvana T; Dornelles, Carlos F D; Arquilla, Bonnie; Bloem, Christina; Roblin, Patricia

    2015-02-01

    On January 27, 2013, a fire at the Kiss Nightclub in Santa Maria, Brazil led to a mass-casualty incident affecting hundreds of college students. A total of 234 people died on scene, 145 were hospitalized, and another 623 people received treatment throughout the first week following the incident.1 Eight of the hospitalized people later died.1 The Military Police were the first on scene, followed by the state fire department, and then the municipal Mobile Prehospital Assistance (SAMU) ambulances. The number of victims was not communicated clearly to the various units arriving on scene, leading to insufficient rescue personnel and equipment. Incident command was established on scene, but the rescuers and police were still unable to control the chaos of multiple bystanders attempting to assist in the rescue efforts. The Municipal Sports Center (CDM) was designated as the location for dead bodies, where victim identification and communication with families occurred, as well as forensic evaluation, which determined the primary cause of death to be asphyxia. A command center was established at the Hospital de Caridade Astrogildo de Azevedo (HCAA) in Santa Maria to direct where patients should be admitted, recruit staff, and procure additional supplies, as needed. The victims suffered primarily from smoke inhalation and many required endotracheal intubation and mechanical ventilation. There was a shortage of ventilators; therefore, some had to be borrowed from local hospitals, neighboring cities, and distant areas in the state. A total of 54 patients1 were transferred to hospitals in the capital city of Porto Alegre (Brazil). The main issues with the response to the fire were scene control and communication. Areas for improvement were identified, namely the establishment of a disaster-response plan, as well as regularly scheduled training in disaster preparedness/response. These activities are the first steps to improving mass-casualty responses.

  6. Overview of EU research activities in transmutation and innovative reactor systems within the Euratom framework programmes

    International Nuclear Information System (INIS)

    Bhatnagar, V.

    2009-01-01

    European Community (EC) (currently 27 Member States) shared-cost research has been organised in Framework Programmes (FP) of durations of 4 - 5 years since 1984. The 6th European Atomic Energy Community (EURATOM) Framework Programme (2002 - 06) and the current 7th FP (2007 - 11) have been allocated a fission research budget respectively of 209 and 287 Million Euro from the EC. There are 10 projects (total budget 70 M Euro, EC contribution 38 M Euro) in all aspects of transmutation ranging from road-mapping exercise to large integrated projects on accelerator driven systems, lead-cooled fast critical systems for waste transmutation, technology, fuel, accelerator facilities for nuclear data etc. In Innovative Reactor concepts, there are about half-a-dozen projects (total budget 30 M Euro, EC contribution 16 M Euro) including High Temperature Reactors, Gas-cooled Fast reactors, road-mapping exercise on sodium fast reactors etc. The main research and training activities in FP7 are: management of radioactive waste, reactor systems, radiation protection, infrastructures, human resources and mobility and training. In the two call for proposals (2007 and 2008) in FP7, 8 projects have been accepted in transmutation and innovative reactor concepts (total budget 53 M Euro, EC contribution 32 M Euro). These research projects cover activities ranging from materials, fuels, treatment of irradiated graphite waste, European sodium fast reactor to the establishment of a Central Design Team of a fast-spectrum transmutation device in Europe. The third call for proposals is underway requesting proposals on nuclear data, thermal hydraulics, gas and lead-cooled fast reactor systems with a total EC budget of 20 M Euro. International collaboration is an important element of the EU research policy. This overview paper will present elements of the strategy of EURATOM research and training in waste management including accelerator driven transmutation systems and Innovative reactor concepts

  7. Do Children’s Health Resources Differ According to Preschool Physical Activity Programmes and Parental Behaviour? A Mixed Methods Study

    Directory of Open Access Journals (Sweden)

    Elena Sterdt

    2014-02-01

    Full Text Available Preschool can have positive effects on the development of a healthy lifestyle. The present study analysed to what extent different conditions, structures and behavioural models in preschool and family—children’s central social microsystems—can lead to differences in children’s health resources. Using a cross-sectional mixed methods approach, contrast analyses of “preschools with systematic physical activity programmes” versus “preschools without physical activity programmes” were conducted to assess the extent to which children’s physical activity, quality of life and social behaviour differ between preschools with systematic and preschools without physical activity programmes. Differences in children’s physical activity according to parental behaviour were likewise assessed. Data on child-related outcomes and parent-related factors were collected via parent questionnaires and child interviews. A qualitative focused ethnographic study was performed to obtain deeper insight into the quantitative survey data. Two hundred and twenty seven (227 children were interviewed at 21 preschools with systematic physical activity programmes, and 190 at 25 preschools without physical activity programmes. There was no significant difference in children’s physical activity levels between the two preschool types (p = 0.709. However, the qualitative data showed differences in the design and quality of programmes to promote children’s physical activity. Data triangulation revealed a strong influence of parental behaviour. The triangulation of methods provided comprehensive insight into the nature and extent of physical activity programmes in preschools and made it possible to capture the associations between systematic physical activity promotion and children’s health resources in a differential manner.

  8. Hypothalamic expression of KiSS-1 system and gonadotropin-releasing effects of kisspeptin in different reproductive states of the female Rat.

    Science.gov (United States)

    Roa, J; Vigo, E; Castellano, J M; Navarro, V M; Fernández-Fernández, R; Casanueva, F F; Dieguez, C; Aguilar, E; Pinilla, L; Tena-Sempere, M

    2006-06-01

    Kisspeptins, products of the KiSS-1 gene with ability to bind G protein-coupled receptor 54 (GPR54), have been recently identified as major gatekeepers of reproductive function with ability to potently activate the GnRH/LH axis. Yet, despite the diversity of functional states of the female gonadotropic axis, pharmacological characterization of this effect has been mostly conducted in pubertal animals or adult male rodents, whereas similar studies have not been thoroughly conducted in the adult female. In this work, we evaluated maximal LH and FSH secretory responses to kisspeptin-10, as well as changes in sensitivity and hypothalamic expression of KiSS-1 and GPR54 genes, in different physiological and experimental models in the adult female rat. Kisspeptin-10 (1 nmol, intracerebroventricular) was able to elicit robust LH bursts at all phases of the estrous cycle, with maximal responses at estrus; yet, in diestrus LH, responses to kisspeptin were detected at doses as low as 0.1 pmol. In contrast, high doses of kisspeptin only stimulated FSH secretion at diestrus. Removal of ovarian sex steroids did not blunt the ability of kisspeptin to further elicit stimulated LH and FSH secretion, but restoration of maximal responses required replacement with estradiol and progesterone. Finally, despite suppressed basal levels, LH and FSH secretory responses to kisspeptin were preserved in pregnant and lactating females, although the magnitude of LH bursts and the sensitivity to kisspeptin were much higher in pregnant dams. Interestingly, hypothalamic KiSS-1 gene expression significantly increased during pregnancy, whereas GPR54 mRNA levels remained unaltered. In summary, our current data document for the first time the changes in hypothalamic expression of KiSS-1 system and the gonadotropic effects (maximal responses and sensitivity) of kisspeptin in different functional states of the female reproductive axis. The present data may pose interesting implications in light of the

  9. The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent

    Directory of Open Access Journals (Sweden)

    Sutcliffe Margaret

    2011-04-01

    Full Text Available Abstract Background Humans and mice with loss of function mutations in GPR54 (KISS1R or kisspeptin do not progress through puberty, caused by a failure to release GnRH. The transcriptional networks regulated by these proteins in the hypothalamus have yet to be explored by genome-wide methods. Results We show here, using 1 million exon mouse arrays (Exon 1.0 Affymetrix and quantitative polymerase chain reaction (QPCR validation to analyse microdissected hypothalamic tissue from Gpr54 and Kiss1 knockout mice, the extent of transcriptional regulation in the hypothalamus. The sensitivity to detect important transcript differences in microdissected RNA was confirmed by the observation of counter-regulation of Kiss1 expression in Gpr54 knockouts and confirmed by immunohistochemistry (IHC. Since Gpr54 and Kiss1 knockout animals are effectively pre-pubertal with low testosterone (T levels, we also determined which of the validated transcripts were T-responsive and which varied according to genotype alone. We observed four types of transcriptional regulation (i genotype only dependent regulation, (ii T only dependent regulation, (iii genotype and T-dependent regulation with interaction between these variables, (iv genotype and T-dependent regulation with no interaction between these variables. The results implicate for the first time several transcription factors (e.g. Npas4, Esr2, proteases (Klk1b22, and the orphan 10-transmembrane transporter TMEM144 in the biology of GPR54/kisspeptin function in the hypothalamus. We show for the neuronal activity regulated transcription factor NPAS4, that distinct protein over-expression is seen in the hypothalamus and hippocampus in Gpr54 knockout mice. This links for the first time the hypothalamic-gonadal axis with this important regulator of inhibitory synapse formation. Similarly we confirm TMEM144 up-regulation in the hypothalamus by RNA in situ hybridization and western blot. Conclusions Taken together, global

  10. The Nuclear Safeguards and Security Activities under Euratom Research and Training Programme

    International Nuclear Information System (INIS)

    Abousahl, S.; Palajova, Z.; Janssens, W.A.M.; Luetzenkirchen, K.; Goncalves, J.G.M.; Aregbe, Y.; )

    2015-01-01

    Nuclear safeguards and security are absolute priorities for the EU. At technical level, the Joint Research Centre (JRC) as the European Commission's in-house science service plays an important role in the field of nuclear research, training and education that include nuclear safety, safeguards and security. The JRC's nuclear research activities are defined in a Council Regulation on the research and training programme of the European Atomic Energy Community. The JRC works closely with EC safeguards authority, whose mission is to ensure that nuclear material within the EU is not diverted from its intended use according to Euratom treaty. Technologies, methodologies and trainings are developed according to the Euratom Safeguards inspectorate's needs. In the area of nuclear security, the JRC contributes to the development of specific expertise in the field of nuclear forensics and border security detection as well as related training efforts for first front-line responders and national experts. The JRC provides its expert support for the implementation of internal EU action plans mainly in the field of radiological and nuclear security. At an international level, the JRC cooperates with the IAEA mainly through the EC support programme on the control of nuclear materials and facilities in order to avoid proliferation or diversion. Close cooperation with IAEA nuclear security is developed through the recent signature of a dedicated practical arrangement. Key partnerships have also been developed in the field of safeguards and security with the US-DoE, Russia, Japan and China. In addition, JRC contributes significantly to the EU nuclear safeguards and security outreach activities implemented under the Instrument for Nuclear Safety Cooperation and Instrument contributing to Stability and Peace. In this paper we will highlight some of the JRC contributions to the enhancement of nuclear safeguards and security at EU and international levels. (author)

  11. Community-based osteoporosis prevention: Physical activity in relation to bone density, fall prevention, and the effect of training programmes : The Vadstena Osteoporosis Prevention Project

    OpenAIRE

    Grahn Kronhed, Ann-Charlotte

    2003-01-01

    This thesis is based on studies of the ten-year community-based intervention programme entitled, the Vadstena Osteoporosis Prevention Project (VOPP). The specific aims of the research were to describe the effects of physical activity and training programmes on bone mass and balance performance in adults, to determine whether a fall risk prevention programme could motivate personal actions among the elderly, to ascertain whether the intervention programme could reduce the incidence of forearm ...

  12. Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo

    DEFF Research Database (Denmark)

    Mikkelsen, J G; Lund, Anders Henrik; Duch, M

    2000-01-01

    synthesis in newly infected cells. We have previously shown that template shifts within the 5' leader of murine leukemia viruses occur preferentially within the kissing stem-loop motif, a cis element crucial for in vitro RNA dimer formation. By use of a forced recombination approach based on single......-cycle transfer of Akv murine leukemia virus-based vectors harboring defective primer binding site sequences, we now report that modifications of the kissing-loop structure, ranging from a deletion of the entire sequence to introduction of a single point mutation in the loop motif, significantly disturb site...... specificity of recombination within the highly structured 5' leader region. In addition, we find that an intact kissing-loop sequence favors optimal RNA encapsidation and vector transduction. Our data are consistent with the kissing-loop dimerization model and suggest that a direct intermolecular RNA...

  13. The SEDIBUD (Sediment Budgets in Cold Environments) Programme: Current activities and future key tasks

    Science.gov (United States)

    Beylich, A. A.; Lamoureux, S. F.; Decaulne, A.

    2012-04-01

    Projected climate change in cold regions is expected to alter melt season duration and intensity, along with the number of extreme rainfall events, total annual precipitation and the balance between snowfall and rainfall. Similarly, changes to the thermal balance are expected to reduce the extent of permafrost and seasonal ground frost and increase active layer depths. These effects will undoubtedly change surface environments in cold regions and alter the fluxes of sediments, nutrients and solutes, but the absence of quantitative data and coordinated process monitoring and analysis to understand the sensitivity of the Earth surface environment is acute in cold climate environments. The International Association of Geomorphologists (I.A.G./A.I.G.)SEDIBUD (Sediment Budgets in Cold Environments) Programme was formed in 2005 to address this existing key knowledge gap. SEDIBUD currently has about 400 members worldwide and the Steering Committee of this international programme is composed of ten scientists from eight different countries: Achim A. Beylich (Chair) (Norway), Armelle Decaulne (Secretary) (France), John C. Dixon (USA), Scott F. Lamoureux (Vice-Chair) (Canada), John F. Orwin (Canada), Jan-Christoph Otto (Austria), Irina Overeem (USA), Thorsteinn Saemundsson (Iceland), Jeff Warburton (UK), Zbigniew Zwolinski (Poland). The central research question of this global group of scientists is to: Assess and model the contemporary sedimentary fluxes in cold climates, with emphasis on both particulate and dissolved components. Initially formed as European Science Foundation (ESF) Network SEDIFLUX (2004-2006), SEDIBUD has further expanded to a global group of researchers with field research sites located in polar and alpine regions in the northern and southern hemisphere. Research carried out at each of the close to 50 defined SEDIBUD key test sites varies by programme, logistics and available resources, but typically represent interdisciplinary collaborations of

  14. On the conformational stability of the smallest RNA kissing complexes maintained through two G·C base pairs

    International Nuclear Information System (INIS)

    Chu, Wally; Weerasekera, Akila; Kim, Chul-Hyun

    2017-01-01

    Two identical 5′GACG3′ tetra-loop motifs with different stem sequences (called H2 and H3) are found in the 5′ end region of Moloney Murine Leukemia Virus (MMLV) genomic RNA. They play important roles in RNA dimerization and encapsidation through two identical tetra-loops (5′GACG3′) forming a loop-to-loop kissing complex, the smallest RNA kissing complex ever found in nature. We examined the effects of a loop-closing base pair as well as a stem sequence on the conformational stability of the kissing complex. UV melting analysis and gel electrophoresis were performed on eight RNA sequences mimicking the H2 and H3 hairpin tetra-loops with variation in loop-closing base pairs. Our results show that changing the loop-closing base pair from the wildtype (5′A·U3′ for H3, 5′U·A3′ for H2) to 5′G·C3’/5′C·G3′ has significant effect on the stability of the kissing complexes: the substitution to 5′C·G3′ significantly decreases both thermal and mechanical stability, while switching to the 5′G·C3′ significantly increases the mechanical stability only. The kissing complexes with the wildtype loop-closing base pairs (5′A·U3′ for H3 and 5′U·A3′ for H2) show different stability when attached to a different stem sequence (H2 stem vs. H3 stem). This suggests that not only the loop-closing base pair itself, but also the stem sequence, affects the conformational stability of the RNA kissing complex. - Highlights: • Thermodynamic parameters of the smallest RNA kissing interactions were measured. • The effects of loop-closing base pairs on the RNA kissing complex was investigated. • Changing the base pair to 5′CG3′ decreases the stability of the kissing complex. • Changing it to 5′GC3′ increases the mechanical resilience of the kissing complex. • Difference in its stem sequence also affects the stability of the kissing complex.

  15. Effectiveness of a Home-Based Active Video Game Programme in Young Cystic Fibrosis Patients.

    Science.gov (United States)

    Del Corral, Tamara; Cebrià I Iranzo, Maria Àngels; López-de-Uralde-Villanueva, Ibai; Martínez-Alejos, Roberto; Blanco, Isabel; Vilaró, Jordi

    2018-01-01

    Exercise-based rehabilitation is already a part of cystic fibrosis (CF) treatment; however, patient adherence is low. To assess the effectiveness of a home exercise programme using active video games (AVGs) as a training modality for children and adolescents with CF. Thirty-nine children with CF were randomised to a control group (CG, n = 20, age 11 ± 6 years; FEV1 86.2 ± 20.5% of predicted) or a training group (AVGG, n = 19, age 13 ± 3 years; FEV1 82.7 ± 21.7% of predicted). The home training protocol consisted of 30- to 60-min sessions, 5 days/week, for 6 weeks using a Nintendo Wii™ platform. Exercise capacity was measured by the 6-min walk test (6MWT) and modified shuttle walk test (MSWT); muscular strength was estimated using the horizontal jump test (HJT), medicine ball throw (MBT), and hand grip strength (right [RHG]; left [LHG]); and quality of life was rated using the Cystic Fibrosis Questionnaire-Revised (CFQ-R). All the children were measured at baseline, after rehabilitation, and at 12 months. For the group × time interaction ANOVAs, the AVGG showed significant between-group differences in exercise capacity: 6MWT farthest walking distance, 38.4 m (p < 0.01); MSWT farthest walking distance, 78.4 m (p < 0.05); and muscular strength: HJT 9.8 cm, MBT 30.8 cm, RHG 7 kg, and LHG 6.5 kg (p < 0.01), before versus after intervention. The CFQ-R reported significantly higher scores on respiratory symptoms after the intervention and favoured the AVGG, and there was an improvement in other domains after 12 months. Adherence to the home exercise programme was 95% during the 6- week intervention period. A home-based programme using AVGs can effectively improve exercise capacity, muscular strength and quality of life in the short-term in children and adolescents with CF. The effects of training on muscle performance and quality of life were sustained over 12 months. © 2017 S. Karger AG, Basel.

  16. The metastasis suppressor KISS1 is an intrinsically disordered protein slightly more extended than a random coil.

    Science.gov (United States)

    Ibáñez de Opakua, Alain; Merino, Nekane; Villate, Maider; Cordeiro, Tiago N; Ormaza, Georgina; Sánchez-Carbayo, Marta; Diercks, Tammo; Bernadó, Pau; Blanco, Francisco J

    2017-01-01

    The metastasis suppressor KISS1 is reported to be involved in the progression of several solid neoplasias, making it a promising molecular target for controlling their metastasis. The KISS1 sequence contains an N-terminal secretion signal and several dibasic sequences that are proposed to be the proteolytic cleavage sites. We present the first structural characterization of KISS1 by circular dichroism, multi-angle light scattering, small angle X-Ray scattering and NMR spectroscopy. An analysis of the KISS1 backbone NMR chemical shifts does not reveal any preferential conformation and deviation from a random coil ensemble. The backbone 15N transverse relaxation times indicate a mildly reduced mobility for two regions that are rich in bulky residues. The small angle X-ray scattering curve of KISS1 is likewise consistent with a predominantly random coil ensemble, although an ensemble optimization analysis indicates some preference for more extended conformations possibly due to positive charge repulsion between the abundant basic residues. Our results support the hypothesis that KISS1 mostly samples a random coil conformational space, which is consistent with its high susceptibility to proteolysis and the generation of Kisspeptin fragments.

  17. KISS1 can be used as a novel target for developing a DNA immunocastration vaccine in ram lambs.

    Science.gov (United States)

    Han, Yanguo; Liu, Guiqiong; Jiang, Xunping; Ijaz, Nabeel; Tesema, Birhanu; Xie, Guangyue

    2015-02-04

    KISS1 gene-encoding kisspeptins are critical for the onset of puberty and control of adult fertility. This study investigated whether KISS1 can be used as a novel target for immunocastration. Human KISS1 was fused with the HBsAg-S gene for constructing an antibiotic-free recombinant plasmid pKS-asd that coded for 31.168 kDa target fusion protein. Six male Hu sheep lambs were divided into two equal groups, treatment and control. The vaccine (1mg/ram lamb) prepared in saline solution was injected into lambs at weeks 0, 3 and 6 of the experiment, respectively. Vaccine efficacy was evaluated in terms of KISS1-specific IgG antibody response, serum testosterone levels, scrotal circumference, testicular weight, length and breadth, extent of testicular tissue damage, and sexual behaviour changes. The specific anti-KISS1 antibody titre in vaccinated animals was significantly higher than that in controls (pvaccinated animals showed lower serum testosterone level, testicular weight and length and smaller scrotal circumference than those in controls (pvaccinated animals was suppressed; sexual behaviours in vaccinated animals were significantly lower (pvaccine induced a strong antibody response and resulted in the suppression of gonadal function and sexual behaviour in animals, demonstrating that KISS1 can be used as a novel target for developing a DNA immunocastration vaccine. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Percutaneous reconstruction of the innominate bifurcation using the retrograde 'kissing stents' technique

    Energy Technology Data Exchange (ETDEWEB)

    Nagata, Shun-ichi; Kazekawa, Kiyoshi; Matsubara, Shuko [Fukuoka University Chikushi Hospital, Department of Neurosurgery, Chikushino, Fukuoka (Japan); Sugata, Sei [Bironoki Neurosurgical Hospital, Shibushi, Kagoshima (Japan)

    2006-08-15

    Obstructions of the supraaortic vessels are an important cause of morbidity associated with a variety of symptoms. Percutaneous transluminal angioplasty has evolved as an effective and safe treatment modality for occlusive lesions of the supraaortic vessels. However, the endovascular management of an innominate bifurcation has not previously been reported. A 53-year-old female with a history of systematic hypertension, diabetes mellitus and hypercholesterolemia presented with left hemiparesis and dysarthria. Angiography of the innominate artery showed a stenosis of the innominate bifurcation. The lesion was successfully treated using the retrograde kissing stent technique via a brachial approach and an exposed direct carotid approach. The retrograde kissing stent technique for the treatment of a stenosis of the innominate bifurcation was found to be a safe and effective alternative to conventional surgery. (orig.)

  19. Percutaneous reconstruction of the innominate bifurcation using the retrograde 'kissing stents' technique

    International Nuclear Information System (INIS)

    Nagata, Shun-ichi; Kazekawa, Kiyoshi; Matsubara, Shuko; Sugata, Sei

    2006-01-01

    Obstructions of the supraaortic vessels are an important cause of morbidity associated with a variety of symptoms. Percutaneous transluminal angioplasty has evolved as an effective and safe treatment modality for occlusive lesions of the supraaortic vessels. However, the endovascular management of an innominate bifurcation has not previously been reported. A 53-year-old female with a history of systematic hypertension, diabetes mellitus and hypercholesterolemia presented with left hemiparesis and dysarthria. Angiography of the innominate artery showed a stenosis of the innominate bifurcation. The lesion was successfully treated using the retrograde kissing stent technique via a brachial approach and an exposed direct carotid approach. The retrograde kissing stent technique for the treatment of a stenosis of the innominate bifurcation was found to be a safe and effective alternative to conventional surgery. (orig.)

  20. Indian Solar Cities Programme: An Overview of Major Activities and Accomplishments; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Kandt, A.

    2012-05-01

    This paper details the Indian Solar City Programme, provides an overview of one city's Master Plan and implementation progress, describes NREL's support of the Indian Solar City Programme, and outlines synergies and differences between the Indian and American programs including unique challenges and opportunities India is facing.

  1. Novel adipokinetic hormones in the kissing bugs Rhodnius prolixus, Triatoma infestans, Dipetalogaster maxima and Panstrongylus megistrus

    Czech Academy of Sciences Publication Activity Database

    Marco, H. G.; Šimek, Petr; Clark, K. D.; Gäde, G.

    2013-01-01

    Roč. 41, MAR 10 (2013), s. 21-30 ISSN 0196-9781 R&D Projects: GA MZd(CZ) NT11513 Grant - others:National Research Foundation(ZA) IFR 2008071500048; National Research Foundation(ZA) FA 2007021300002 Institutional support: RVO:60077344 Keywords : insects * kissing bugs * reduviidae Subject RIV: ED - Physiology Impact factor: 2.614, year: 2013 http://www.sciencedirect.com/science/article/pii/S0196978112004433

  2. Ghana's nuclear programme

    International Nuclear Information System (INIS)

    Ahafia, Albert K.

    1988-01-01

    The Paper gives the purpose of Ghana's Nuclear Programme and describes some specific research activities and peaceful applications of atomic energy in agriculture, medicine and industry. A discussion of some of the problem facing the programme concludes the Paper. (author)

  3. Senior expert group for the review of the Agency`s programme of activities. Opening remarks by the Director General

    Energy Technology Data Exchange (ETDEWEB)

    ElBaradei, M [International Atomic Energy Agency, Vienna (Austria)

    1998-03-23

    The document reproduces the opening remarks made by the Director General of the IAEA on 23 March 1998 at the first meeting of the Senior Expert Group for the review of the Agency`s programme and activities. The Director General explains his considerations in establishing the group, and the major challenges facing the safe use of nuclear energy and technologies

  4. Decrease in heart rate after longitudinal participation in the Groningen Active Living Model (GALM) recreational sports programme

    NARCIS (Netherlands)

    de Jong, Johan; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby; Stevens, Martin

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement

  5. Longitudinal changes in heart rate after participating in the Groningen Active Living Model (GALM) recreational sports programme

    NARCIS (Netherlands)

    de Jong, Johan; Lemmink, Koen; Scherder, Erik; Stewart, Roy; King, Abby C.

    2009-01-01

    The aim of this study was to investigate changes in heart rate during submaximal exercise as an index of cardiovascular function in older adults participating in the Groningen Active Living Model recreational sports programme who were sedentary or underactive at baseline. A repeated measurement

  6. Impact of a Six-Month Empowerment-Based Exercise Intervention Programme in Non-Physically Active Adolescent Swedish Girls

    Science.gov (United States)

    Lindgren, Eva-Carin; Baigi, Amir; Apitzsch, Erwin; Bergh, Hakan

    2011-01-01

    Objective: This study evaluated changes in self-efficacy in non-physically active adolescent girls (13-19 years old) who participated in a six-month, empowerment-based exercise intervention programme (EIP). Design: The study used a pre- and post-test randomized group design and included one pre- and one post-test (at six months) and non-physically…

  7. Effects of Leisure Education Programme Including Sportive Activities on Perceived Freedom in Leisure of Adolescents with Intellectual Disabilities

    Science.gov (United States)

    Ertuzun, Ezgi

    2015-01-01

    The objective of this experimental study is to determine the effect of leisure education programme including sportive activities on the perceived freedom in leisure of adolescents with mild intellectual disabilities. The research was designed with an experimental group (n = 37) and a control group (n = 34), and was conducted among a total of 71…

  8. Senior expert group for the review of the Agency's programme of activities. Opening remarks by the Director General

    International Nuclear Information System (INIS)

    ElBaradei, M.

    1998-01-01

    The document reproduces the opening remarks made by the Director General of the IAEA on 23 March 1998 at the first meeting of the Senior Expert Group for the review of the Agency's programme and activities. The Director General explains his considerations in establishing the group, and the major challenges facing the safe use of nuclear energy and technologies

  9. Study protocol: using the Q-STEPS to assess and improve the quality of physical activity programmes for the elderly.

    Science.gov (United States)

    Marques, Ana I; Rosa, Maria J; Amorim, Marlene; Soares, Pedro; Oliveira-Tavares, António; Santos, Rute; Mota, Jorge; Carvalho, Joana

    2012-07-09

    Aging is one of the most important and obvious phenomenon observed in our society. In the past years, there has been a growing concern in designing physical activity (PA) programmes for elderly people, because evidence suggests that such health promotion interventions may reduce the deleterious effects of the ageing process. Accordingly, a growing body of literature points to the importance of a sound approach to planning and evaluation in order to improve the quality of PA programmes. However, while numerous PA programmes have been designed for the elderly in recent years, their evaluation has been scarce. Quality management processes and tools provide a practical way for organisations to assess, identify and shed light on the areas requiring improvement. The Quality Self-assessment Tool for Exercise Programmes for Seniors (Q-STEPS) seems to provide a framework tailored to evaluate PA programmes for the elderly. The primary purpose of this study is 1) to determine feasibility, acceptability and usability of the Q-STEPS. Secondary purposes of the study are: 2) to examine the quality of the PA programmes for elderly people developed by the Portuguese Local Administration over a three-year period of self-assessments in terms of: a) Enabler domains (Leadership, Policy and Strategy, People, Partnership and Resources, Processes); b) Result domains (Customer Results, People Results, Society Results and Key Performance Results); 3) to estimate the association between the use of Q-STEPS and some indicators relating to the elderly participants, during the three self-assessments, such as: attendance rates, physical fitness, health-related quality of life and the elderly's perceived quality of the programme. The study will be conducted in PA programmes for elderly adults from mainland Portuguese municipalities over a three-year period. The project will adopt a participative quality improvement approach that features annual learning cycles of: 1) self-assessment with the Q

  10. Controlled ecological evaluation of an implemented exercise training programme to prevent lower limb injuries in sport: differences in implementation activity.

    Science.gov (United States)

    Donaldson, Alex; Gabbe, Belinda J; Lloyd, David G; Cook, Jill; Finch, Caroline F

    2018-04-24

    The public health benefits of injury prevention programmes are maximised when programmes are widely adopted and adhered to. Therefore, these programmes require appropriate implementation support. This study evaluated implementation activity outcomes associated with the implementation of FootyFirst, an exercise training injury prevention programme for community Australian football, both with (FootyFirst+S) and without (FootyFirst+NS) implementation support. An evaluation plan based on the Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) Sports Setting Matrix was applied in a controlled ecological evaluation of the implementation of FootyFirst. RE-AIM dimension-specific (range: 0-2) and total RE-AIM scores (range: 0-10) were derived by triangulating data from a number of sources (including surveys, interviews, direct observations and notes) describing FootyFirst implementation activities. The mean dimension-specific and total scores were compared for clubs in regions receiving FootyFirst+S and FootyFirst+NS, through analysis of variance. The mean total RE-AIM score forclubs in the FootyFirst+S regions was 2.4 times higher than for clubs in the FootyFirst+NS region (4.73 vs 1.94; 95% CI for the difference: 1.64 to 3.74). Similarly, all dimension-specific scores were significantly higher for clubs in the FootyFirst+S regions compared with clubs in the FootyFirst+NS region. In all regions, the dimension-specific scores were highest for reach and adoption, and lowest for implementation. Implementing exercise training injury prevention programmes in community sport is challenging. Delivering programme content supported by a context-specific and evidence-informed implementation plan leads to greater implementation activity, which is an important precursor to injury reductions. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise

  11. [Congenital "kissing" lesions: Nevus or "café au lait" spot?

    Science.gov (United States)

    Durazzo, A; Boccara, O; Fraitag, S; Fusade, T; Picard, A; Kadlub, N

    2016-12-01

    "Café au lait" spots (CLS) are pigmented skin lesions principally located at the trunk and the limbs. Histologically, CLSs consist in an excessive pigmentation of the epidermis, with no risk of malignant transformation. The "kissing" nevus is a rare pigmented congenital nevus affecting both lower and upper eyelids in a mirror layout. As other nevi, it presents a theoretical risk of malignant transformation. These two pigmented lesions are responsible for aesthetic discomfort when affecting the face. Three patients presenting with a congenital pigmented lesion affecting the two eyelids in a mirror layout are presented. In two cases, the lesions, initially considered as "kissing" nevi, were classified as CLSs. The diagnosis of CLS was made on a biopsy in one patient and after surgery in the other one. Pigmented mirror layout lesions, called "kissing" lesions, are exclusively described for the nevi. We describe two cases of CLSs affecting the eyelids in a mirror layout. Difficulties in diagnostic are exposed and the possible treatments are discussed. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  12. Prevalence and persistence of male DNA identified in mixed saliva samples after intense kissing.

    Science.gov (United States)

    Kamodyová, Natália; Durdiaková, Jaroslava; Celec, Peter; Sedláčková, Tatiana; Repiská, Gabriela; Sviežená, Barbara; Minárik, Gabriel

    2013-01-01

    Identification of foreign biological material by genetic profiling is widely used in forensic DNA testing in different cases of sexual violence, sexual abuse or sexual harassment. In all these kinds of sexual assaults, the perpetrator could constrain the victim to kissing. The value of the victim's saliva taken after such an assault has not been investigated in the past with currently widely used molecular methods of extremely high sensitivity (e.g. qPCR) and specificity (e.g. multiplex Y-STR PCR). In our study, 12 voluntary pairs were tested at various intervals after intense kissing and saliva samples were taken from the women to assess the presence of male DNA. Sensitivity-focused assays based on the SRY (single-copy gene) and DYS (multi-copy gene) sequence motifs confirmed the presence of male DNA in female saliva after 10 and even 60min after kissing, respectively. For specificity, standard multiplex Y-STR PCR profiling was performed and male DNA was found in female saliva samples, as the entire Y-STR profile, even after 30min in one sample. Our study confirms that foreign DNA tends to persist for a restricted period of time in the victim's mouth, can be isolated from saliva after prompt collection and can be used as a valuable source of evidence. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  13. Hydrogen activities in the European Union work-programme; Activites liees a l'hydrogene dans le programme de travail de l'Union Europeenne

    Energy Technology Data Exchange (ETDEWEB)

    Bahbout, A.; Tartaglia, G.P. [Joint Research Centre, IHCP, Ispra (Italy)

    2000-07-01

    vehicles using hydrogen have joined forces with the aim of improving the coordination of licensing and approval procedures needed for putting hydrogen powered vehicles on the road. The 5. Framework Programme eventually includes hydrogen activities, even if no specific reference is made to hydrogen, following the policy of the Commission to provide directions and fund research according to broad objectives. Hydrogen appears integrated in the wider context of the thematic lines of the work programme. In the programme 'Energy, Environment and Sustainable Development', the activities are concerned with the generation of electricity, and/or heat, with reduced CO{sub 2} emissions from biomass or other fuels. Moreover, development, demonstration, integration of new and renewable energy sources into energy systems is foreseen. Specifically for fuel cells: independent evaluation of their performance against standardised measurement procedures, study of materials involved and possibilities for improvement (abstract only). (authors)

  14. JRC/IE support activities to PHARE nuclear safety programmes. Dissemination of PHARE project results

    International Nuclear Information System (INIS)

    Ranguelova, V.; Pla, P.; Rieg, C.; Bieth, M.

    2005-01-01

    Nuclear safety in Europe is one of European Union's primary concerns, therefore the European Union decided to take a prominent role to help the New Independent States and countries of Central and Eastern Europe to ensure the safety of their nuclear reactors. The European Union TACIS and PHARE programmes in nuclear safety have been undertaken since 1990. The European Commission's Directorate General External Relations (EC DG RELEX) and, Directorate General Europe Aid Co-operation Office (EC DG AIDCO), are responsible for programming and management of implementation of TACIS projects. Directorate General Enlargement (EC DG ELARG) is responsible for programming PHARE programmes, but implementation of most projects has been decentralised since 1999 budget year to the Beneficiary countries. DG ELARG acts as backstopping for the relevant EC Delegations. In these activities, the TSSTP Unit at the JRC/IE in Petten, The Netherlands, is a technical and scientific adviser of DG RELEX and DG AIDCO and provides support to DG ELARG for very specific technical issues. Several PHARE projects aiming at improving nuclear safety have been successfully implemented for a number of plants from Central and Eastern Europe. In some cases major safety issues have been addressed by means of multi-country projects and results have been disseminated to the rest of the nuclear community. Although a lot of information has been exchanged at a bilateral level, further effort is needed to collect the project results in a systematic way and make them available by means of the internet. At present the TSSTP Unit is implementing two projects for dissemination of PHARE project results. This activity will take a better advantage of today's communication technologies and ensure the management of the acquired knowledge through preservation and user-friendly access and retrieval of the project results. The paper provides an outline of the TSSTP Unit relevant knowledge preservation initiative, a description

  15. Programme wood/energy 2000-2006. Activity Report for 2000-2004

    International Nuclear Information System (INIS)

    2006-01-01

    When ADEME launched its Wood fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report makes a status of ADEME's Wood fuel programme for the 2000-2004 era: - Domestic heating: After a drop during the 1990's, figures since 1999 of sales of wood-fuel domestic heating equipment (closed heaters, glass-door fires and stoves) have shown a significant rise. On average over 30 years, wood consumption has risen to 7.2 million TOE (40 million cubic metres) per year; - Industry: It is thought there are 1000 wood-fired heaters (above 1 megawatt) used in French industry. These are found mainly in timber-based industries and in timber crushing plants. This amounts to a total power output of 2.5 gigawatts. In the primary and secondary wood processing industries, the increase in the number of wood-fired boilers and energy produced has reached 5% per year Results of a call for carbon energy projects (APEC) was 61 submitted of which 52 were selected; 9 projects pending (166.5 K of aid from ADEME); and 35 projects begun (1,649 K of aid from ADEME). - Local authority and service sector wood-fired heating systems: At the end of 2004, the number of local authority active boilers was 641, producing 430 megawatts. This is an increase of an average of 13% year on year since 2000. By the end of 2004, the target had already been met for the number of boilers being financed (1,090). By 2006 however we still need to generate a

  16. Conditions for Employee Learning and Innovation--Interweaving Competence Development Activities Provided by a Workplace Development Programme with Everyday Work Activities in SMEs

    Science.gov (United States)

    Halvarsson Lundkvist, Agneta; Gustavsson, Maria

    2018-01-01

    The aim of this article is to investigate how the formal competence development activities provided by the Production Leap, a workplace development programme (WPDP), were interwoven with everyday work activities and to identify the conditions that enabled learning and employee-driven innovation that contributed to production improvement, in small…

  17. Outcomes of the single-stent versus kissing-stents technique in asymmetric complex aortoiliac bifurcation lesions.

    Science.gov (United States)

    Suh, Yongsung; Ko, Young-Guk; Shin, Dong-Ho; Kim, Jung-Sun; Kim, Byeong-Keuk; Choi, Donghoon; Hong, Myeong-Ki; Jang, Yangsoo

    2015-07-01

    This study investigated the outcomes of single-stent vs kissing-stents techniques in asymmetric complex aortoiliac bifurcation (ACAB) lesions. We retrospectively investigated 80 consecutive patients (69 males, 66.6 ± 8.7 years) treated with a single stent and 30 patients (26 males, 67.1 ± 7.7 years) treated with kissing stents for ACAB between January 2005 and December 2012 from a single-center cohort. A ACAB lesion was defined as a symptomatic unilateral common iliac artery stenosis (>50%) combined with intermediate stenosis (30%-50%) in the contralateral common iliac artery ostium. The primary end point was the primary patency of the ACAB. The baseline clinical characteristics did not differ significantly between the single-stent and the kissing-stents group. Technical success was achieved in all patients. The single-stent group required fewer stents (1.3 ± 0.5 vs 2.3 ± 0.8; P stent group (3%) required bailout kissing stents because of plaque shift to the contralateral side. The major complication rates were 8% in single-stent vs 13% in the kissing-stent group, which was similar (P = .399). At 3 years, the single-stent and kissing-stents group had similar rates of primary patency (89% vs 87%; P = .916) and target lesion revascularization-free survival (93% vs 87%; P = .462). The single-stent technique in ACAB was safe and showed midterm outcomes comparable with those of kissing stents. Considering the benefits, such as fewer stents, less bilateral femoral access, and the availability of contralateral access for future intervention, the single-stent technique may be an advantageous treatment option in ACAB. Copyright © 2015 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  18. RPII Inspection and Licensing Activities and Annual Inspection Programme for 2014

    International Nuclear Information System (INIS)

    Fennell, S.

    2014-04-01

    The purpose of this document is to promote transparency in the activities of the Radiological Protection Institute of Ireland discussed herein. It explains aspects of the internal workings of the Regulation and Information Management Division of the RPII to aid understanding of the processes and decisions of that Division which may impact on licensees and other interested parties. Every effort has been made to ensure the accuracy and completeness of information contained herein, but the RPII does not warrant such accuracy or completeness and lists of procedures and criteria may not be exhaustive. The reader should also bear in mind that the actual inspection programme and related procedures or criteria may be altered or revised in the course of the year in response to new developments. This is a guidance and information document and, while the RPII is available to advise and assist generally with regulatory queries, the information so provided or contained in this document is of a general nature and is not intended to address the specific circumstances of any particular party. This document is not intended as a legal interpretation of the legislation that applies to the RPII or of the obligations of parties operating in spheres covered by that legislation. Parties wishing to be advised on such matters should consult their legal advisers

  19. Impact of a personalised active labour market programme for persons with disabilities.

    Science.gov (United States)

    Adamecz-Völgyi, Anna; Lévay, Petra Zsuzsa; Bördős, Katalin; Scharle, Ágota

    2018-02-01

    The paper estimates the impact of a supported employment programme implemented in Hungary. This is a non-experimental evaluation using a matching identification strategy supported by rich data on individual characteristics, personal employment and unemployment history and the local labour market situation. We use a time-window approach to ensure that programme participants and matched controls entered unemployment at the same point in time, and thus faced very similar labour market conditions. We find that the programme had a positive effect of 16 percentage points on the probability of finding a job among men and 25 percentage points among women. The alternative outcome indicator of not re-entering the unemployment registry shows somewhat smaller effects in the case of women. In comparison to similarly costly programmes that do not facilitate employment in the primary labour market, rehabilitation services represent a viable alternative.

  20. Development of an education and training programme for radiation protection officers in facilities and activities

    International Nuclear Information System (INIS)

    Mutwamezi, Tekla

    2015-02-01

    Education and training is a crucial matter in radiation protection and it is considered a regulatory requirement. For this reason, this project work focused on developing an education and training programme for Radiation Protection Officers whose overall function is to oversee radiation protection and safety at the work place. The developed education and training programme has adopted both the class room based and on the job training methods. Additionally, the programme is organized into 6 modules and focuses on fundamentals of radioactivity; biological effects; legislation; principles of radiation protection; assessment and protection against occupational exposure; medical exposure (only applicable to Radiation Protection Officers in the medical sector) and emergency preparedness and response. The purpose of the programme is to provide Radiation Protection Officers with the basic knowledge and skills to function effectively to meet radiation safety and regulatory requirements. (au)

  1. A multidisciplinary TBI inpatient rehabilitation programme for active duty service members as part of a randomized clinical trial.

    Science.gov (United States)

    Braverman, S E; Spector, J; Warden, D L; Wilson, B C; Ellis, T E; Bamdad, M J; Salazar, A M

    1999-06-01

    To design and describe an effective rehabilitation programme for use in an ongoing trial on the efficacy of multidisciplinary brain injury rehabilitation for moderately head injury military service members. Treatment arm of a randomized control trial. US military tertiary care hospital inpatient rehabilitation programme. Sixty seven active duty military with moderate to severe TBI who were randomized to the treatment arm of the protocol. Eight week rehabilitation programme combining group and individual therapies with an inpatient milieu-oriented neuropsychological focus. Group therapies included fitness, planning and organization, cognitive skills, work skills, medication, and milieu groups, and community re-entry outings. Individual therapy included neuropsychology, work therapy, occupational therapy, and speech and language pathology. Successful return to work and return to duty. At 1 year follow-up, 64 patients returned to work (96%) and 66% (44/67) returned to duty. The described rehabilitation programme demonstrates one successful effort to rehabilitate active duty military service members with TBI who have the potential to return to duty.

  2. 'Doing with …' rather than 'doing for …' older adults: rationale and content of the 'Stay Active at Home' programme.

    Science.gov (United States)

    Metzelthin, Silke F; Zijlstra, Gertrud Ar; van Rossum, Erik; de Man-van Ginkel, Janneke M; Resnick, Barbara; Lewin, Gill; Parsons, Matthew; Kempen, Gertrudis Ijm

    2017-11-01

    Owing to increasing age, accidents or periods of illness, home care services are provided to community-dwelling older adults. Traditionally, these services focus on doing things for older adults rather than with them; though from a rehabilitative perspective, it is important to assist older adults to attain and maintain their highest level of functioning. Consequently, a re-orientation of home care services is required away from treating disease and creating dependency towards focusing on capabilities and opportunities and maximising independence. To achieve this behavioural change in home care professionals, the 'Stay Active at Home' programme was developed. The aim of this article is to give a detailed description of the rationale and content of the 'Stay Active at Home' programme by making use of the TIDieR (Template for Intervention Description and Replication) Checklist. 'Stay Active at Home' is a comprehensive training programme that aims to equip home care professionals (i.e. community nurses and domestic support workers) with the necessary knowledge, attitude, skills and social and organisational support to deliver day-to-day services at home from a more rehabilitative perspective. More specifically, home care professionals are expected to deliver goal-oriented, holistic and person-centred services focusing on supporting older adults to maintain, gain or restore their competences to engage in physical and daily activities so that they can manage their everyday life as independently as possible.

  3. The Impact of Adventure Based Activity at Malaysian National Service Training Programme on Team Cohesion: A Demographic Analysis.

    OpenAIRE

    Jaffry Zakaria; Mazuki Mohd Yasim; Md Amin Md Taff

    2012-01-01

    The present study examines the effects of physical module elements (adventure based activity) included in the Malaysian National Service Programme and to investigate the socio-demographic variables impact on team cohesion building among the participants. In this study, the participants were selected from three different camps, namely, Tasoh camp, Guar Chenderai camp and Meranti camp, located in the state of Perlis, Malaysia. The participants were those from the second batch intake in the yea...

  4. Technology Programme

    Energy Technology Data Exchange (ETDEWEB)

    Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo [ed.

    2005-07-01

    The technology activities carried out by the Euratom-ENEA Association in the framework of the European Fusion Development Agreement concern the Next Step (International Thermonuclear Experimental Reactor - ITER), the Long-Term Programme (breeder blanket, materials, International Fusion Materials Irradiation Facility - IFMIF), Power Plant Conceptual Studies and Socio-Economic Studies. The Underlying Technology Programme was set up to complement the fusion activities as well to develop technologies with a wider range of interest. The Technology Programme mainly involves staff from the Frascati laboratories of the Fusion Technical and Scientific Unit and from the Brasimone laboratories of the Advanced Physics Technologies Unit. Other ENEA units also provide valuable contributions to the programme. ENEA is heavily engaged in component development/testing and in design and safety activities for the European Fusion Technology Programme. Although the work documented in the following covers a large range of topics that differ considerably because they concern the development of extremely complex systems, the high level of integration and coordination ensures the capability to cover the fusion system as a whole. In 2004 the most significant testing activities concerned the ITER primary beryllium-coated first wall. In the field of high-heat-flux components, an important achievement was the qualification of the process for depositing a copper liner on carbon fibre composite (CFC) hollow tiles. This new process, pre-brazed casting (PBC), allows the hot radial pressing (HRP) joining procedure to be used also for CFC-based armour monoblock divertor components. The PBC and HRP processes are candidates for the construction of the ITER divertor. In the materials field an important milestone was the commissioning of a new facility for chemical vapour infiltration/deposition, used for optimising silicon carbide composite (SiCf/SiC) components. Eight patents were deposited during 2004

  5. Technology Programme

    International Nuclear Information System (INIS)

    Batistoni, Paola; De Marco, Francesco; Pieroni, Leonardo

    2005-01-01

    The technology activities carried out by the Euratom-ENEA Association in the framework of the European Fusion Development Agreement concern the Next Step (International Thermonuclear Experimental Reactor - ITER), the Long-Term Programme (breeder blanket, materials, International Fusion Materials Irradiation Facility - IFMIF), Power Plant Conceptual Studies and Socio-Economic Studies. The Underlying Technology Programme was set up to complement the fusion activities as well to develop technologies with a wider range of interest. The Technology Programme mainly involves staff from the Frascati laboratories of the Fusion Technical and Scientific Unit and from the Brasimone laboratories of the Advanced Physics Technologies Unit. Other ENEA units also provide valuable contributions to the programme. ENEA is heavily engaged in component development/testing and in design and safety activities for the European Fusion Technology Programme. Although the work documented in the following covers a large range of topics that differ considerably because they concern the development of extremely complex systems, the high level of integration and coordination ensures the capability to cover the fusion system as a whole. In 2004 the most significant testing activities concerned the ITER primary beryllium-coated first wall. In the field of high-heat-flux components, an important achievement was the qualification of the process for depositing a copper liner on carbon fibre composite (CFC) hollow tiles. This new process, pre-brazed casting (PBC), allows the hot radial pressing (HRP) joining procedure to be used also for CFC-based armour monoblock divertor components. The PBC and HRP processes are candidates for the construction of the ITER divertor. In the materials field an important milestone was the commissioning of a new facility for chemical vapour infiltration/deposition, used for optimising silicon carbide composite (SiCf/SiC) components. Eight patents were deposited during 2004

  6. The metastasis suppressor gene KISS-1 regulates osteosarcoma apoptosis and autophagy processes.

    Science.gov (United States)

    Yin, Yiran; Tang, Lian; Shi, Lei

    2017-03-01

    The expression of the metastasis suppressor gene KISS-1 in osteosarcoma cells during apoptosis and autophagy was evaluated. MG-63 osteosarcoma cells were transfected with either KISS-1 overexpression or KISS-1 knockdown expression vector in vitro, and compared with cell lines transfected with empty vector. After 12, 24, 48 and 72 h of cell culture, the cell proliferation was examined. The MTT method was used to detect apoptosis by flow cytometry, and the mRNA levels of apoptosis and autophagy markers caspase-3, Bcl-2, Bax, LC3 and Beclin1 were assessed by RT-PCR. Our results showed that cells in the control and low expression group kept proliferating during the cell culture period of 72 h, while the cells in the overexpression group progressively decreased in number. Also, the proliferation rate of the low expression group was significantly higher than that of the control group. The relative mRNA expression levels of caspase-3 and Bax mRNA in the control and low expression group showed no change (the expression was lowest in the low expression group). Moreover, the mRNA level of Bcl-2 increased in both cell groups. The mRNA expression levels of caspase-3 and Bax in the overexpression group were increased, and the level of Bcl-2 was reduced significantly. At the same time, the relative expression level of LC3 and Beclin1 mRNA in the control and low expression groups remained the same, and that of the overexpression group increased. The mRNA levels of LC3 and Beclin1 in the overexpression group were the highest, and that of the low expression group the lowest. The differences were statistically significant (Posteosarcoma in vitro, probably by accelerating the processes of apoptosis and autophagy in the cells.

  7. Theory Meets Experiment: Metal Ion Effects in HCV Genomic RNA Kissing Complex Formation

    Directory of Open Access Journals (Sweden)

    Li-Zhen Sun

    2017-12-01

    Full Text Available The long-range base pairing between the 5BSL3. 2 and 3′X domains in hepatitis C virus (HCV genomic RNA is essential for viral replication. Experimental evidence points to the critical role of metal ions, especially Mg2+ ions, in the formation of the 5BSL3.2:3′X kissing complex. Furthermore, NMR studies suggested an important ion-dependent conformational switch in the kissing process. However, for a long time, mechanistic understanding of the ion effects for the process has been unclear. Recently, computational modeling based on the Vfold RNA folding model and the partial charge-based tightly bound ion (PCTBI model, in combination with the NMR data, revealed novel physical insights into the role of metal ions in the 5BSL3.2-3′X system. The use of the PCTBI model, which accounts for the ion correlation and fluctuation, gives reliable predictions for the ion-dependent electrostatic free energy landscape and ion-induced population shift of the 5BSL3.2:3′X kissing complex. Furthermore, the predicted ion binding sites offer insights about how ion-RNA interactions shift the conformational equilibrium. The integrated theory-experiment study shows that Mg2+ ions may be essential for HCV viral replication. Moreover, the observed Mg2+-dependent conformational equilibrium may be an adaptive property of the HCV genomic RNA such that the equilibrium is optimized to the intracellular Mg2+ concentration in liver cells for efficient viral replication.

  8. Endovascular Management of Aorta-Iliac Stenosis and Occlusive Disease by Kissing-Stent Technique

    Directory of Open Access Journals (Sweden)

    Meng Liu

    2016-01-01

    Full Text Available Kissing-stenting treatment has been used to treat patients with peripheral artery disease (PAD. However, the long term efficacy of the stenting therapy is not well defined in Chinese PAD patients. To investigate the question, sixty-three PAD patients (37 males and 26 females, aged 66±7.3 years, were analysed in the study. They were featured as claudication (n=45, 71.4%, rest pain (n=18, 28.6%, or gangrene (n=8, 12.7%. In total, 161 stents were applied in aorta-iliac lesions with 2.6 stents for each patient, including 55 self-expanding stents, 98 balloon expandable stents, and 8 covered stents. The success rate of implanting Kissing-stents was 100%. Catheter-directed thrombolysis (CDT with urokinase was performed in 8 cases (12.7%. The severity of peripheral ischemia was significantly improved, as evidenced by 3.3-fold increase of ankle-brachial pressure index (ABI after the surgery (P=0.008. One, three, five, and seven years after surgery, the primary patency rate was 87.3%, 77.4%, 71.1%, and 65.0%, whereas the secondary patency rate was 95.2%, 92.5%, 89.5%, and 85.0%, respectively. No in-hospital mortality was recorded. In conclusion, Kissing-stenting technique for aorta-iliac lesions is safe and effective with lower complications. It is beneficial for aorta-iliac occlusions that are longer than 60 mm.

  9. The mass miniature chest radiography programme in Cape Town, South Africa, 1948-1994: The impact of active tuberculosis case finding

    NARCIS (Netherlands)

    Hermans, S. M.; Andrews, J. R.; Bekker, L.-G.; Wood, R.

    2016-01-01

    Tuberculosis (TB) control programmes rely mainly on passive detection of symptomatic individuals. The resurgence of TB has rekindled interest in active case finding. Cape Town (South Africa) had a mass miniature radiography (MMR) screening programme from 1948 to 1994. To evaluate screening coverage,

  10. Defining the cause of reduced progesterone levels during pregnancy in Kiss1/Gpr54 mutant mice

    OpenAIRE

    MILLÁN ESTEBAN, DAVID

    2015-01-01

    [ES] La kisspeptina, un neuropéptido codificado por el gen Kiss1, es requerida para la activación del eje reproductivo en la pubertad en los mamíferos y para el mantenimiento de la fertilidad en adultos. Los ratones que no tienen kisspeptina o que tienen mutaciones en el correspondiente receptor, GPR54, no entran en la pubertad y son estériles. Tienen gónadas subdesarrolladas (hipogonadismo), bajos niveles de hormona gonadotrópica (hipogonadotropismo), y bajos niveles de esteroides sexuales....

  11. Effect of an aerobic-based physical activity programme on physical ...

    African Journals Online (AJOL)

    The purpose of this study was to determine whether a 10 week aerobic-based exercise programme performed twice a week, with a 30 minutes duration and an intensity level of 55 – 70% heart rate max would improve aerobic endurance, muscular strength, muscular endurance, flexibility and body composition of 10 – 15 ...

  12. Similarities between intra- and intermolecular hydrogen bonds in RNA kissing complexes found by means of cross-correlated relaxation

    International Nuclear Information System (INIS)

    Dittmer, Jens; Kim, Chul-Hyun; Bodenhausen, Geoffrey

    2003-01-01

    The bond lengths and dynamics of intra- and intermolecular hydrogen bonds in an RNA kissing complex have been characterized by determining the NMR relaxation rates of various double- and triple-quantum coherences that involve an imino proton and two neighboring nitrogen-15 nuclei belonging to opposite bases. New experiments allow one to determine the chemical shift anisotropy of the imino protons. The bond lengths derived from dipolar relaxation and the lack of modulations of the nitrogen chemical shifts indicate that the intermolecular hydrogen bonds which hold the kissing complex together are very similar to the intramolecular hydrogen bonds in the double-stranded stem of the RNA

  13. Conditions for Employee Learning and Innovation : Interweaving Competence Development Activities Provided by a Workplace Development Programme with Everyday Work Activities in SMEs

    OpenAIRE

    Halvarsson Lundkvist, Agneta; Maria, Gustavsson

    2018-01-01

    The aim of this article is to investigate how the formal competence development activities provided by the Production Leap, a workplace development programme (WPDP), were interwoven with everyday work activities and to identify the conditions that enabled learning and employee-driven innovation that contributed to production improvement, in small and medium-sized enterprises (SMEs) in Sweden. The study adopts a qualitative case approach and draws on evidence from research conducted in four ma...

  14. A Sweet Vaccination – the Deadly Hershey’s Kiss

    Directory of Open Access Journals (Sweden)

    Ann H. Williams

    2011-03-01

    Full Text Available In Immunology courses, concepts such as primary and secondary immune response and the topic of vaccinations can be difficult to visualize for students. Described here is a short activity where students choose and snack on candy to simulate primary and secondary immune responses in the context of a vaccination. This short interactive activity is performed in the lecture course of Immunology, an upper-division Biology course that contains mostly Biology major juniors or seniors (class of 30–40. It is performed on the first day of class, and is consistently referred to as the semester progresses and more complex and detailed topics are introduced. It is utilized to help students understand and visualize the process of primary immune response, secondary immune response, immunological memory, and vaccinations.

  15. Sexual activity as a trigger of myocardial infarction. A case-crossover analysis in the Stockholm Heart Epidemiology Programme (SHEEP)

    DEFF Research Database (Denmark)

    Möller, J; Ahlbom, A; Hulting, J

    2001-01-01

    .9). CONCLUSIONS: The increased risk of myocardial infarction after sexual activity and the further increase in risk among the less physically fit support the hypothesis of causal triggering by sexual activity. However, the absolute risk per hour is very low, and exposure is relatively infrequent. Thus having sex......OBJECTIVE: To investigate sexual activity as a trigger of myocardial infarction and the potential effect modification of physical fitness. DESIGN: A case-crossover study nested in the Stockholm Heart Epidemiology Programme (SHEEP). SETTING: Stockholm County from April 1993 to December 1994...... once a week only increases the annual risk of myocardial infarction slightly. Counselling should focus on encouraging patients to live a physically active life and not on abstaining from sexual activity....

  16. Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA

    Directory of Open Access Journals (Sweden)

    Eric R. Gamache

    2017-04-01

    Full Text Available The genomic RNA of the retrotransposon Ty1 is packaged as a dimer into virus-like particles. The 5′ terminus of Ty1 RNA harbors cis-acting sequences required for translation initiation, packaging and initiation of reverse transcription (TIPIRT. To identify RNA motifs involved in dimerization and packaging, a structural model of the TIPIRT domain in vitro was developed from single-nucleotide resolution RNA structural data. In general agreement with previous models, the first 326 nucleotides of Ty1 RNA form a pseudoknot with a 7-bp stem (S1, a 1-nucleotide interhelical loop and an 8-bp stem (S2 that delineate two long, structured loops. Nucleotide substitutions that disrupt either pseudoknot stem greatly reduced helper-Ty1-mediated retrotransposition of a mini-Ty1, but only mutations in S2 destabilized mini-Ty1 RNA in cis and helper-Ty1 RNA in trans. Nested in different loops of the pseudoknot are two hairpins with complementary 7-nucleotide motifs at their apices. Nucleotide substitutions in either motif also reduced retrotransposition and destabilized mini- and helper-Ty1 RNA. Compensatory mutations that restore base-pairing in the S2 stem or between the hairpins rescued retrotransposition and RNA stability in cis and trans. These data inform a model whereby a Ty1 RNA kissing complex with two intermolecular kissing-loop interactions initiates dimerization and packaging.

  17. Can Population-Level Laterality Stem from Social Pressures? Evidence from Cheek Kissing in Humans.

    Science.gov (United States)

    Chapelain, Amandine; Pimbert, Pauline; Aube, Lydiane; Perrocheau, Océane; Debunne, Gilles; Bellido, Alain; Blois-Heulin, Catherine

    2015-01-01

    Despite extensive research, the origins and functions of behavioural laterality remain largely unclear. One of the most striking unresolved issues is the fact that laterality generally occurs at the population-level. Why would the majority of the individuals of a population exhibit the same laterality, while individual-level laterality would yet provide the advantages in terms of improving behavioural efficiency? Are social pressures the key factor? Can social pressures induce alignment of laterality between the individuals of a population? Can the effect of social pressures overpass the effect of other possible determining factors (e.g. genes)? We tested this important new hypothesis in humans, for the first time. We asked whether population-level laterality could stem from social pressures. Namely, we assessed social pressures on laterality in an interactive social behaviour: kissing on the cheek as a greeting. We performed observations in 10 cities of France. The observations took place in spots where people of the city meet and greet each other. We showed that: a) there is a population-level laterality for cheek kissing, with the majority of individuals being aligned in each city, and b) there is a variation between populations, with a laterality that depends on the city. These results were confirmed by our complementary data from questionnaires and internet surveys. These findings show that social pressures are involved in determining laterality. They demonstrate that population-level laterality can stem from social pressures.

  18. Can Population-Level Laterality Stem from Social Pressures? Evidence from Cheek Kissing in Humans.

    Directory of Open Access Journals (Sweden)

    Amandine Chapelain

    Full Text Available Despite extensive research, the origins and functions of behavioural laterality remain largely unclear. One of the most striking unresolved issues is the fact that laterality generally occurs at the population-level. Why would the majority of the individuals of a population exhibit the same laterality, while individual-level laterality would yet provide the advantages in terms of improving behavioural efficiency? Are social pressures the key factor? Can social pressures induce alignment of laterality between the individuals of a population? Can the effect of social pressures overpass the effect of other possible determining factors (e.g. genes? We tested this important new hypothesis in humans, for the first time. We asked whether population-level laterality could stem from social pressures. Namely, we assessed social pressures on laterality in an interactive social behaviour: kissing on the cheek as a greeting. We performed observations in 10 cities of France. The observations took place in spots where people of the city meet and greet each other. We showed that: a there is a population-level laterality for cheek kissing, with the majority of individuals being aligned in each city, and b there is a variation between populations, with a laterality that depends on the city. These results were confirmed by our complementary data from questionnaires and internet surveys. These findings show that social pressures are involved in determining laterality. They demonstrate that population-level laterality can stem from social pressures.

  19. Valve-Like and Protruding Calcified Intimal Flap Complicating Common Iliac Arteries Kissing Stenting

    Directory of Open Access Journals (Sweden)

    George S. Georgiadis

    2015-01-01

    Full Text Available Endovascular therapy for iliac artery chronic total occlusions is nowadays associated with low rates of procedure-related complications and improved clinical outcomes, and it is predominantly used as first-line therapy prior to aortobifemoral bypass grafting. Herein, we describe the case of a patient presenting with an ischemic left foot digit ulcer and suffering complex aortoiliac lesions, who received common iliac arteries kissing stents, illustrating at final antegrade and retrograde angiograms the early recognition of a blood flow obstructing valve-like calcified intimal flap protruding through the stent struts, which was obstructing antegrade but not retrograde unilateral iliac arterial axis blood flow. The problem was resolved by reconstructing the aortic bifurcation at a more proximal level. Completion angiogram verified normal patency of aorta and iliac vessels. Additionally, a severe left femoral bifurcation stenosis was also corrected by endarterectomy-arterioplasty with a bovine patch. Postintervention ankle brachial pressure indices were significantly improved. At the 6-month and 2-year follow-up, normal peripheral pulses were still reported without intermittent claudication suggesting the durability of the procedure. Through stent-protruding calcified intimal flap, is a very rare, but existing source of antegrade blood flow obstruction after common iliac arteries kissing stents.

  20. How music alters a kiss: superior temporal gyrus controls fusiform–amygdalar effective connectivity

    Science.gov (United States)

    Deserno, Lorenz; Bakels, Jan-Hendrik; Schlochtermeier, Lorna H.; Kappelhoff, Hermann; Jacobs, Arthur M.; Fritz, Thomas Hans; Koelsch, Stefan; Kuchinke, Lars

    2014-01-01

    While watching movies, the brain integrates the visual information and the musical soundtrack into a coherent percept. Multisensory integration can lead to emotion elicitation on which soundtrack valences may have a modulatory impact. Here, dynamic kissing scenes from romantic comedies were presented to 22 participants (13 females) during functional magnetic resonance imaging scanning. The kissing scenes were either accompanied by happy music, sad music or no music. Evidence from cross-modal studies motivated a predefined three-region network for multisensory integration of emotion, consisting of fusiform gyrus (FG), amygdala (AMY) and anterior superior temporal gyrus (aSTG). The interactions in this network were investigated using dynamic causal models of effective connectivity. This revealed bilinear modulations by happy and sad music with suppression effects on the connectivity from FG and AMY to aSTG. Non-linear dynamic causal modeling showed a suppressive gating effect of aSTG on fusiform–amygdalar connectivity. In conclusion, fusiform to amygdala coupling strength is modulated via feedback through aSTG as region for multisensory integration of emotional material. This mechanism was emotion-specific and more pronounced for sad music. Therefore, soundtrack valences may modulate emotion elicitation in movies by differentially changing preprocessed visual information to the amygdala. PMID:24298171

  1. How music alters a kiss: superior temporal gyrus controls fusiform-amygdalar effective connectivity.

    Science.gov (United States)

    Pehrs, Corinna; Deserno, Lorenz; Bakels, Jan-Hendrik; Schlochtermeier, Lorna H; Kappelhoff, Hermann; Jacobs, Arthur M; Fritz, Thomas Hans; Koelsch, Stefan; Kuchinke, Lars

    2014-11-01

    While watching movies, the brain integrates the visual information and the musical soundtrack into a coherent percept. Multisensory integration can lead to emotion elicitation on which soundtrack valences may have a modulatory impact. Here, dynamic kissing scenes from romantic comedies were presented to 22 participants (13 females) during functional magnetic resonance imaging scanning. The kissing scenes were either accompanied by happy music, sad music or no music. Evidence from cross-modal studies motivated a predefined three-region network for multisensory integration of emotion, consisting of fusiform gyrus (FG), amygdala (AMY) and anterior superior temporal gyrus (aSTG). The interactions in this network were investigated using dynamic causal models of effective connectivity. This revealed bilinear modulations by happy and sad music with suppression effects on the connectivity from FG and AMY to aSTG. Non-linear dynamic causal modeling showed a suppressive gating effect of aSTG on fusiform-amygdalar connectivity. In conclusion, fusiform to amygdala coupling strength is modulated via feedback through aSTG as region for multisensory integration of emotional material. This mechanism was emotion-specific and more pronounced for sad music. Therefore, soundtrack valences may modulate emotion elicitation in movies by differentially changing preprocessed visual information to the amygdala. © The Author (2013). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  2. [Analysis of fourteen French national programmes on physical activity and sports as determinants of health from 2001 to 2006].

    Science.gov (United States)

    Bréchat, Pierre-Henri; Vogel, Thomas; Berthel, Marc; Kaltenbach, Georges; Le Divenah, Aude; Segouin, Christophe; Rymer, Roland; Lonsdorfer, Jean

    2009-01-01

    Physical activity and sports are considered as one of the determinants of health. The aim of this study is to review the rationale for the formulation of this public health issue and its integration in national action plans. The study shows that fourteen national programmes were drafted and implemented between 2001 and 2006 by seven institutions. The research methodology was based on crossing data obtained from semi-directed interviews and documents regarding the design, implementation and follow-up of these programmes. For the conditions of the success, the fourteen actions scored an average of 175.0 +/- 66.9 out of 300%. Public health actors and professionals must be given more opportunities to involve themselves and engage in developing stronger relationships and linkages, in particular with the institutional and community settings. In general, the most invested parts of a programme are the structural and operational aspects of activities. Six significant points surfaced from the study: consideration of drug use as an addictive behaviour; recognition of the psychological stress of professional athletes; acknowledgment of youth as being at high risk for doping behaviour; integration of the concept that physical activity and sports must take the benefit/risk perspective into account; and the necessity to promote health. Through the exchange of numerous local and regional experiences, an optimisation of their synergistic connections was made possible on a continuum extending from "health promotion through physical activity and sports" to "prevention of drug-use and doping behaviours". Professionals have been able to develop actions in the above-mentioned domains across this continuum that have, to date, remained isolated. Proposals are made to strengthen these dynamics. Other health determinants and public health priorities could be investigated with the same methodology.

  3. REVIEW OF THE NATIONAL RESTOCKING PROGRAMMEACTIVE PROTECTION OF NATIVE CRAYFISH IN POLAND” 1999-2001

    Directory of Open Access Journals (Sweden)

    ŠMIETANA P.

    2004-01-01

    Full Text Available After the first spread of crayfish plague (aphanomycosis at the end of the nineteenth century, the formerly abundant populations of native crayfish in Poland declined drastically. Analysis of historical data on the occurrence and distribution of crayfish in Poland led to the conclusion that without human intervention the native crayfish species would be at high risk of being made extinct. The largest programme concerning crayfish monitoring and restocking in Poland was “Active protection of native crayfish in Poland” conducted by the Inland Fisheries Institute, the Department of Ecology, University of Szczecin, the Department of Zoology, Warsaw Agricultural University and the University of Warmia and Mazury that was funded by the EkoFundusz Foundation and Inland Fisheries Institute in 1999-2001. One of the main objectives and results of this programme was the determination of indigenous crayfish distribution in Poland (mainly Astacus astacus and Astacus leptodactylus and the restocking of suitable habitats with indigenous crayfish. The densest populations (> 2 500 adult individuals per hectare were used as a source of restocking material. Restocking was performed in 54 water bodies using a total of 45 200 individuals of A. astacus and 9 800 of A. leptodactylus. Between 2001-2002, the success of the restocking programme was monitored. According to the results obtained so far, the restocking exercise has been successful in at least 60.8% of the cases.

  4. Systematisch literatuuronderzoek naar de effecten van behandeling bij zuigelingen met 'kopgewrichteninvloed bij storingen in de symmetrie' ('KISS-syndroom')

    NARCIS (Netherlands)

    Brand, P. L. P.; Engelbert, R. H. H.; Helders, P. J. M.; Offringa, M.

    2005-01-01

    OBJECTIVE: To establish the effects of manual therapy, chiropractic, or osteopathic treatment of the KISS-syndrome (kinetic imbalance due to suboccipital strain) in infants with positional preference, plagiocephaly, and colic. DESIGN: Systematic review of the literature. METHOD: PubMed, Embase and

  5. Differential regulation of kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters

    DEFF Research Database (Denmark)

    Ansel, L; Bolborea, M; Bentsen, A H

    2010-01-01

    ). In rodents, Kiss1 is expressed in the anteroventral periventricular nucleus (AVPV) and in the arcuate nucleus (ARC). Because both the duration of the nocturnal peak of melatonin and circulating sex steroid levels vary with photoperiod, the aim of this study was to determine whether melatonin and sex steroids...

  6. Polymorphisms rs12998 and rs5780218 in KiSS1 Suppressor Metastasis Gene in Mexican Patients with Breast Cancer

    Directory of Open Access Journals (Sweden)

    Edhit Guadalupe Cruz Quevedo

    2015-01-01

    Full Text Available Aims. KiSS1 is a metastasis suppressor gene associated with inhibition of cellular chemotaxis and invasion attenuating the metastasis in melanoma and breast cancer cell lines. Along the KiSS-1 gene at least 294 SNPs have been described; however the association of these polymorphisms as genetic markers for metastasis in breast cancer studies has not been investigated. Here we describe two simple PCR-RFLPs protocols to identify the rs5780218 (9DelT and the rs12998 (E20K KiSS1 polymorphisms and the allelic, genotypic, and haplotypic frequencies in Mexican general population (GP and patients with benign breast disease (BBD or breast cancer (BC. Results. The rs5780218 polymorphism was individually associated with breast cancer (P=0.0332 and the rs12998 polymorphism shows statistically significant differences when GP versus case (BC and BBD groups were compared (P<0.0001. The H1 Haplotype (G/- occurred more frequently in BC group (0.4256 whereas H2 haplotype (G/T was the most prevalent in BBD group (0.4674. Conclusions. Our data indicated that the rs5780218 polymorphism individually confers susceptibility for development of breast cancer in Mexican population and a possible role as a genetic marker in breast cancer metastasis for H1 haplotype (Wt/variant in KiSS1 gene must be analyzed in other populations.

  7. A structured physical activity and fitness programme for older adults with intellectual disabilities: results of a cluster-randomised clinical trial.

    Science.gov (United States)

    van Schijndel-Speet, M; Evenhuis, H M; van Wijck, R; van Montfort, K C A G M; Echteld, M A

    2017-01-01

    The physical activity level of older adults with intellectual disabilities (ID) is extremely low, and their fitness levels are far beneath accepted norms for older people with normal intelligence and comparable with frail older people. A physical activity programme, including an education programme, was developed for older adults with ID using behaviour change techniques. The programme aimed at improving or maintaining adequate levels of physical activity (primary outcome measure) and motor fitness, cardio respiratory fitness, morphologic and metabolic fitness, activities of daily living, cognitive functioning and depressive symptoms (secondary outcome measures). The programme's efficacy was evaluated in a cluster-randomised clinical trial among people aged 43 years and over with mild-moderate levels of ID. Five day-activity centres were randomised to the participation group. In these centres, 81 older adults participated in groups of 8 to 10 in the programme, three times a week during 8 months. The programme was executed by physical activity instructors and staff of day-activity centres. Five other day-activity centres were randomised to the control group; 70 older adults in these centres received care as usual. The generalised linear model with mixed effects was used to test the programme's effectiveness. Significant effects were found on physical activity, muscle strength, systolic and diastolic blood pressure, serum cholesterol level and cognitive functioning, in favour of the programme's participants. No significant improvements were found on balance, serum glucose, weight, waist circumference, walking speed, mobility, depression or instrumental activities of daily living. The physical activity and fitness programme has established small but significant effects in this sample, but generalising the findings to other settings is difficult due to significant participant dropout. Implementation of evidence-based physical activity programmes among older adults

  8. Playing after work? Opportunities and challenges of a physical activity programme for female cleaners

    DEFF Research Database (Denmark)

    Lenneis, Verena; Pfister, Gertrud Ursula

    2016-01-01

    experience with sport and exercise and struggled with the high demands at work and a “second shift” at home. As a consequence, most participants found the training too time- and energy-consuming. We conclude that exercise programmes should preferably be conducted at the workplace and during working hours....... factors constrained and which supported participation. The interviews revealed a high degree of appreciation for the training but also pointed to a number of constraints which were embedded into the participants’ biographies and everyday lives as migrant cleaners in Denmark. Most women had no previous...

  9. Pendulum : une extension réactive pour la programmation Web en OCaml

    OpenAIRE

    El Sibaïe , Rémy; Chailloux , Emmanuel

    2016-01-01

    International audience; La programmation des interactions des différents composants d'une application Web est devenue particulièrement complexe tant au niveau de la conception que de la mise au point. Peu de garanties peuvent être apportées sur la coordination des interactions internes et les réactions aux événements externes reposant sur le modèle de concurrence de JavaScript. Il devient alors nécessaire de proposer un modèle de concurrence simple améliorant cette situation. Dans ce cadre, c...

  10. A Swedish co-operation programme for radiological emergency planning activities in the Baltic Sea region

    International Nuclear Information System (INIS)

    Petersson, B.

    1998-01-01

    Short overview of the Swedish cooperation projects with Baltic countries in the field of radiological emergency preparedness is presented. Cooperation programme is going since 1993 and is divided into following sections: sub-projects on planning, training and exercises, sub-projects on measurement strategies, including early warning systems, sub-project on information to the public and the media, sub-projects on review of the Ignalina NPP on-site emergency preparedness and planning of on-site rescue operations. Total budget amount allocated for these projects is 9 million Swedish crowns

  11. Active Play in After-school Programmes: development of an intervention and description of a matched-pair cluster-randomised trial assessing physical activity play in after-school programmes.

    Science.gov (United States)

    Riiser, Kirsti; Helseth, Sølvi; Ellingsen, Hanna; Fallang, Bjørg; Løndal, Knut

    2017-08-04

    Interventions delivered in after-school programmes (ASPs) have the potential to become a means of ensuring adequate physical activity among schoolchildren. This requires a motivational climate, allowing for self-determined play. If trained, ASP staff may represent a valuable resource for supporting such play. Increasing knowledge and supportive skills among ASP staff may also potentially increase their motivation for work. The purpose of this article is to describe the development of the 'Active Play in ASP' intervention, which aims to promote physical activity among first graders attending ASP, and to present a protocol for a matched-pair cluster-randomised trial to evaluate the intervention. Informed by experiences from practice, evidence-based knowledge and theory, the intervention was developed in a stepwise process including focus group meetings and a small-scale pilot test. The intervention contains a course programme for ASP staff to increase their skills in how to support physical activity through play. In a cluster randomised controlled trial, the ASPs will be matched and randomly allocated to receive the 7-month intervention or to a control group. Outcomes will be assessed at baseline, after 7 and 19 months. First graders attending the ASPs included are eligible. The primary outcome will be accelerometer-determined minutes in moderate to vigorous physical activity in the ASP. The study uses a mixed methods approach including observations and interviews to provide rich descriptions of the concept of children's physical activity in ASP. Moreover, the trial will assess whether the ASP staff benefits from participation in the intervention in terms of increased work motivation. Lastly, process evaluations of programme fidelity, satisfaction and suggestions on improvement will be performed. The study is approved by the Data Protection Official for Research (reference no 46008). Results will be presented in conferences and peer-reviewed journals. Clinical Trials

  12. The special programme of research in human reproduction: forty years of activities to achieve reproductive health for all.

    Science.gov (United States)

    Benagiano, Giuseppe; d'Arcangues, Catherine; Harris Requejo, Jennifer; Schafer, Alessandra; Say, Lale; Merialdi, Mario

    2012-01-01

    The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of existing fertility-regulating methods, as well as developing new, improved modalities for family planning. In 1994, HRP not only made major contributions to the Plan of Action of the International Conference on Population and Development (ICPD); it also broadened its scope of work to include other aspects of health dealing with sexuality and reproduction, adding a specific perspective on gender issues and human rights. In 2002, HRP's mandate was once again broadened to include sexually transmitted infections and HIV/AIDS and in 2003 it was further expanded to research activities on preventing violence against women and its many dire health consequences. Today, the work of the Programme includes research on: the sexual and reproductive health of adolescents, women, and men; maternal and perinatal health; reproductive tract and sexually transmitted infections (including HIV/AIDS); family planning; infertility; unsafe abortion; sexual health; screening for cancer of the cervix in developing countries, and gender and reproductive rights. Additional activities by the Programme have included: fostering international cooperation in the field of human reproduction; the elaboration of WHO's first Global Reproductive Health Strategy; work leading to the inclusion of ICPD's goal 'reproductive health for all by 2015' into the Millennium Development Goal framework; the promotion of critical interagency statements on the public health, legal, and human rights implications of female genital mutilation and gender-biased sex selection. Finally, HRP has been involved in the creation of guidelines and tools, such as the 'Medical eligibility criteria for contraceptive use

  13. Efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children: the healthy homework pilot study

    Directory of Open Access Journals (Sweden)

    Duncan Scott

    2011-11-01

    Full Text Available Abstract Background Most physical activity and nutrition interventions in children focus on the school setting; however, evidence suggests that children are less active and have greater access to unhealthy food at home. The aim of this pilot study was to examine the efficacy of a compulsory homework programme for increasing physical activity and healthy eating in children. Methods The six-week 'Healthy Homework' programme and complementary teaching resource was developed under the guidance of an intersectoral steering group. Eight senior classes (year levels 5-6 from two diverse Auckland primary schools were randomly assigned into intervention and control groups. A total of 97 children (57 intervention, 40 control aged 9-11 years participated in the evaluation of the intervention. Daily step counts were monitored immediately before and after the intervention using sealed multiday memory pedometers. Screen time, sports participation, active transport to and from school, and the consumption of fruits, vegetables, unhealthy foods and drinks were recorded concurrently in a 4-day food and activity diary. Results Healthy Homework resulted in a significant intervention effect of 2,830 steps.day-1 (95% CI: 560, 5,300, P = 0.013. This effect was consistent between sexes, schools, and day types (weekdays and weekend days. In addition, significant intervention effects were observed for vegetable consumption (0.83 servings.day-1, 95% CI: 0.24, 1.43, P = 0.007 and unhealthy food consumption (-0.56 servings.day-1, 95% CI: -1.05, -0.07, P = 0.027 on weekends but not weekdays, with no interactions with sex or school. Effects for all other variables were not statistically significant regardless of day type. Conclusions Compulsory health-related homework appears to be an effective approach for increasing physical activity and improving vegetable and unhealthy food consumption in children. Further research in a larger study is required to confirm these initial

  14. Research programme 'Active Solar Energy Use - Solar Heating and Heat Storage'. Activities and projects 2003; Programme 'Solaire actif - Chaleur et Stockage de chaleur'. Activites et projets en 2003

    Energy Technology Data Exchange (ETDEWEB)

    Hadorn, J.-C. [Base Consultants, Geneva (Switzerland); Renaud, P. [Planair SA, La Sagne (Switzerland)

    2003-07-01

    In this report by the research, development and demonstration (RD+D) programme coordinators the objectives, activities and main results in the area of solar heating and heat storage in Switzerland are presented for 2003. In a stagnating market environment the strategy of the Swiss Federal Office of Energy mainly consists in improving the quality and durability of solar collectors and materials, optimizing combisystems for space heating and domestic hot water preparation, searching for storage systems with a higher energy storage density than in the case of sensible heat storage in water, developing coloured solar collectors for more architectonic freedom, and finalizing a seasonal heat storage project for 100 dwellings to demonstrate the feasibility of solar fractions larger than 50% in apartment houses. Support was granted to the Swiss Testing Facility SPF in Rapperswil as in previous years; SPF was the first European testing institute to perform solar collector labeling according to the new rules of the 'Solar Keymark', introduced in cooperation with the European Committee for Standardization CEN. Several 2003 projects were conducted within the framework of the Solar Heating and Cooling Programme of the International Energy Agency IEA. Computerized simulation tools were improved. With the aim of jointly producing high-temperature heat and electric power a solar installation including a concentrating collector and a thermodynamic machine based on a Rankine cycle is still being developed. Seasonal underground heat storage was studied in detail by means of a validated computer simulation programme. Design guidelines were obtained for such a storage used in the summer time for cooling and in the winter time for space heating via a heat pump: depending on the ratio 'summer cooling / winter heating', cooling requires a cooling machine, or direct cooling without such a machine is possible. The report ends up with the list of all supported RD

  15. Physical activity and psychological well-being in obese pregnant and postpartum women attending a weight-gain restriction programme.

    Science.gov (United States)

    Claesson, Ing-Marie; Klein, Sofia; Sydsjö, Gunilla; Josefsson, Ann

    2014-01-01

    the objective of the study was to compare the differences in psychological well-being and quality of life during pregnancy and post partum of obese physically active women and obese physically inactive women enroled in a weight gain restriction programme. We also wanted to explore whether physical activity influences weight change or health status during pregnancy. a prospective intervention study. antenatal care clinic. a total of 74 obese pregnant women in a physically active group and 79 obese women in a physically inactive group. the women kept diaries of their physical activity during pregnancy and answered the Beck Anxiety Inventory, the Edinburgh Postnatal Depression Scale and Medical Study Short-Form Health Survey in gestational weeks 15 and 35 and 11 weeks post partum. Physical activity was measured in metabolic equivalents. the physically active women experienced fewer depressive symptoms and estimated an improved quality of life during their pregnancies as measured by physical functioning, bodily pain, social functioning, role limitations due to emotional problems and general mental health as compared with the physically inactive women. There were no differences between the groups in gestational weight gain or weight change from early pregnancy to post partum or in prevalence of complications. physical activity among obese pregnant women provides better psychological well-being and improved quality of life, but does not prevent weight change. staff at Antenatal Care Clinics that face obese pregnant women, should encourage and emphasise the benefits of being physically active throughout pregnancy. Copyright © 2012 Elsevier Ltd. All rights reserved.

  16. Improved cognitive performance in preadolescent Danish children after the school-based physical activity programme "FIFA 11 for Health" for Europe - A cluster-randomised controlled trial

    DEFF Research Database (Denmark)

    Lind, Rune Rasmussen; Geertsen, Svend Sparre; Ørntoft, Christina

    2018-01-01

    programme. The programme combines small-sided football games, drills and health education. Cognitive performance was evaluated at baseline and follow-up. RESULTS: The IG improved their cognitive performance compared to the CG for psychomotor function (56, sx- = 22 ms, p attention (39, sx- = 17 ms......, p = .012) and working memory (79, sx- = 35 ms, p = .020). CONCLUSION: This pilot study provides evidence that the school-based physical activity programme "FIFA 11 for Health" for Europe can improve cognitive performance in preadolescent Danish schoolchildren. Future studies should attempt...

  17. A multi-modal training programme to improve physical activity, physical fitness and perceived physical ability in obese children.

    Science.gov (United States)

    Morano, Milena; Colella, Dario; Rutigliano, Irene; Fiore, Pietro; Pettoello-Mantovani, Massimo; Campanozzi, Angelo

    2014-01-01

    Actual and perceived physical abilities are important correlates of physical activity (PA) and fitness, but little research has explored these relationships over time in obese children. This study was designed: (a) to assess the feasibility of a multi-modal training programme promoting changes in PA, fundamental motor skills and real and perceived physical abilities of obese children; and (b) to explore cross-sectional and longitudinal relationships between real and perceived physical competence in boys and girls. Forty-one participants (9.2 ± 1.2 years) were assessed before and after an 8-month intervention with respect to body composition, physical fitness, self-reported PA and perceived physical ability. After treatment, obese children reported improvements in the body mass index, PA levels, gross motor performance and actual and perceived physical abilities. Real and perceived physical competence was correlated in boys, but not in girls. Results indicate that a multi-modal programme focused on actual and perceived physical competence as associated with the gradual increase in the volume of activity might be an effective strategy to improve adherence of the participants and to increase the lifelong exercise skills of obese children.

  18. Playing after work? Opportunities and challenges of a physical activity programme for female cleaners

    DEFF Research Database (Denmark)

    Lenneis, Verena; Pfister, Gertrud Ursula

    2016-01-01

    The workplace is regarded as an ideal setting for health promotion, not least because large sections of the population, including “high risk groups”, can be reached. One group which is reportedly in great demand of health promotion is that of female (migrant) cleaners – the participants in our...... factors constrained and which supported participation. The interviews revealed a high degree of appreciation for the training but also pointed to a number of constraints which were embedded into the participants’ biographies and everyday lives as migrant cleaners in Denmark. Most women had no previous...... experience with sport and exercise and struggled with the high demands at work and a “second shift” at home. As a consequence, most participants found the training too time- and energy-consuming. We conclude that exercise programmes should preferably be conducted at the workplace and during working hours....

  19. 2000-2006 National Wood Energy Programme. 2000-2005 Activities Report

    International Nuclear Information System (INIS)

    2006-01-01

    2005 was marked by key decisions which were taken with the aim of developing the biomass sector as a substitute for fossil fuels. Indeed, to achieve the ambitious objectives for renewable sources of energy set out by the July 2005 Energy Policy Orientation Programme (POPE), we must make great use of biomass, particularly to increase by 50% the share of renewable thermal energy between now and 2010 and to enable biofuels to represent 7% of all fuels used at the same date. To a lesser extent, and in conjunction with heat production, the share of biomass in renewable electricity production also needs to rise. Both the resource and key supply players are there and are ready to get organised in order to rise to these challenges. There is an abundant supply of agricultural and forest by-products. More than sixty companies organise and deliver heating wood. More than 300 government and professional promotion, regulatory, PR, finance, equipment construction and operation, research and engineering organizations are involved in this market. The strategic and economic context is highly favourable in the light of laws, directives and international agreements aiming to combat greenhouse gas emissions, but also due to the structural pressure on the price of fossil fuels. Wood energy, as a renewable energy source, has an important role to play in this context of growth. Furthermore, the wood energy sector should be developed using an exemplary sustainable development approach, which means that all the economic, social and environmental effects are taken into account. In order to comprehensively assess the sector's environmental impact, a full chapter of this report presents the work and programmes set up by ADEME to reduce pollutant emissions produced by biomass combustion, particularly from private households. Moreover, consultation and dialogue between those involved must be widened in order to enable all wood users to benefit from 'best forest use' which will be a key

  20. National Wood-fuel Programme 2000-2006. Activity Report 2000-2006

    International Nuclear Information System (INIS)

    2008-01-01

    When ADEME launched its Wood-fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood-fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report presents: 1 - the Wood Energy stakes for the environment, for employment, and for the economy, the biomass energy net benefits; 2 - the Wood Energy key figures: Production and consumption, Single-family homes and wood heating, Breakdown of types of devices used, Sales of wood-fired devices, Number of housing/institutional boilers in use, Number of industrial boilers in use; 3 - the Wood Energy objectives: Domestic heating, Industrial boiler plants, District heating for housing/institutional/commercial uses; 4 - the Wood Energy program operation: Program coordination by ADEME, Partnerships and State-Region planning agreements, 2000-2006 funding system (modified in 2004) and Other financial instruments; 5 - the 2000-2006 assessment: Main results, Conclusions and recommendations, Evaluation contributions: five key points, Evaluation of employment in the solid biofuels supply chain, Supply for community, institutional and commercial boilers; 6 - Information and communication: Initiatives supported or accompanied by ADEME between 2000 and 2004, Publications supported by ADEME. In appendix: fuels and energy content, regional assessments, national research program on bio-energies - PNRB 2006 (Review and stakes, PNRB results in 2006), wood heating R and D, studies funded by ADEME, 2006 ADEME's correspondents, glossary

  1. Hierarchy of kissing numbers for exceptional Lie symmetry groups in high energy physics

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2008-01-01

    We are constructing a hierarchy of kissing numbers representing singular contact points of hyper-spheres in exceptional Lie symmetry groups lattice arrangement embedded in the 26 dimensional bosonic strings spacetime. That way we find a total number of points and dimensions equal to 548. This is 52 more than the order of E 8 E 8 of heterotic string theory and leads to the prediction of 69 elementary particles at an energy scale under 1 T. In other words, our mathematical model predicts nine more particles than what is currently experimentally known to exist in the standard model of high energy physics namely only 60. The result is thus in full agreement with all our previous theoretical findings

  2. Influence of Astaxanthin and β-carotene on Kissing Gourami (Helostoma temminckii Colouring

    Directory of Open Access Journals (Sweden)

    Ján Kopecký

    2012-10-01

    Full Text Available This study evaluated the role of carotenoids in regulate the skin color of Kissing Gourami (Helostoma temminckii. 40 fishes were randomly selected into 2 groups (20 each group. Control group was fed with standard flake feed. Astaxanthin (12mg/kg and β-carotene (157 mg/kg were added to the standard diet for experimental group. Fish skin colour was compare with colour scale. Colour change was recorded weekly for the 12 weeks of experiment. First colour change was record in 5 th week in control group. No other change of colour was determinate. In experimental group was first colour change in 3rd week and the maximal influence of carotenoids was recorded in 8th week. No other colour change was record in experimental group to the end of experiment.

  3. Análise do gene KISS1 nos distúrbios puberais humanos

    OpenAIRE

    Letícia Ferreira Gontijo Silveira

    2009-01-01

    A kisspeptina, codificada pelo gene KISS1, é um neuropeptídeo crucial na regulação do início da puberdade. A kisspeptina estimula a secreção hipotalâmica do hormônio liberador de gonadotrofinas (GnRH) após se ligar ao seu receptor GPR54. Mutações inativadoras do GPR54 são atualmente consideradas como uma causa rara de hipogonadismo hipogonadotrófico isolado (HHI) normósmico. Recentemente, uma mutação ativadora no receptor GPR54 foi implicada na patogênese da puberdade precoce dependente de go...

  4. Simultaneous kissing stents for the treatment of left main stenosis in cardiogenic shock

    International Nuclear Information System (INIS)

    Rahman, N.; Dhakam, S.; Nadeem, N.

    2007-01-01

    Significant narrowing of the left main coronary artery puts the patient at high risk, since occlusion of this vessel, if unprotected by collateral flow or a patent bypass graft to either the left anterior descending or circumflex artery, compromises flow to approximately 75% of the left ventricle. Percutaneous coronary intervention of left main coronary artery may be the only life saving procedure. There are limited data on the general use of percutaneous intervention (PCI) in patients with acute myocardial infarction (MI) due to left main disease. Small series have noted in-hospital mortality rates of 30 to 35 percent following PCI with or without stenting. Moreover, cardiogenic shock secondary to acute MI, in patients with left main coronary artery disease, carries a very high mortality. Treatment options are limited especially when emergent coronary artery bypass surgery is not an option. We report a case of emergency angioplasty of left main coronary artery with simultaneous kissing stent technique in cardiogenic shock. (author)

  5. Radiologic findings consistent with kissing spines syndrome in Chilean thoroughbreds horses

    Directory of Open Access Journals (Sweden)

    Dario Infante

    2016-12-01

    Full Text Available Alterations in the thoracolumbar spine of racehorses are frequent and often significantly decrease their athletic performance. The most common thoracolumbar alteration in thoroughbred horses is kissing spines syndrome (KSS. The narrowing of the interespinous space, generally located between T14-T15 and T15-T16, produces this syndrome. A radiographic study was performed to 30 thoroughbred horses on the segment between T12 and T18. Two latero-lateral views from digital equipment were obtained of the T12 to T18 segment of each horse, the images were analyze and the radiographic findings established the KSS according to a grading scale. The study sample was homogeneous and the results were similar to other radiographic findings of KSS occurring in segments T14-T15 and T15-16.

  6. Investigations on tunneling and kissing bond defects in FSW joints for dissimilar aluminum alloys

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Noor Zaman, E-mail: noor_0315@yahoo.com [Department of Mechanical Engineering, Jamia Millia Islamia (A Central University), New Delhi (India); Siddiquee, Arshad Noor; Khan, Zahid A. [Department of Mechanical Engineering, Jamia Millia Islamia (A Central University), New Delhi (India); Shihab, Suha K. [Department of Mechanical Engineering, Engineering College, Diyala University, Diyala (Iraq)

    2015-11-05

    In this paper an attempt has been made to investigate the effect of two Friction Stir Welding (FSW) parameters i.e. tool pin offset and tool plunge depth on the formation of defects such as tunnel (tunneling defect) and kissing bond (KB) during welding of dissimilar aluminum alloys. 4.75 mm thick plates of AA5083-H116 and AA6063-T6 were welded using a novel work-fixture developed in-house which, apart from clamping the plated also imparted continuous variation of offset on both side of the faying line. The tunneling defect was modeled as a function of offset and plunge depth. The welds were characterised using optical microscopy (OM), scanning electron microscopy (SEM) and mechanical testing. The causes of such defects have been analyzed and discussed and recommendations have been made to prevent their occurrence. The findings of the study have revealed that the tunneling defects are formed at all offset (including zero offset) values towards stronger material (advancing side). And the cross-section of the tunnel varied with the amount of offset. Further, KBs are formed at the interface for all pin offset values except 0.5 mm towards weaker material and high plunge depth resulting in the poor mechanical properties. - Highlights: • Two dissimilar aluminum alloys are welded using FSW. • Formation of kissing bond and tunneling defects are investigated. • Defects are formed at pin offsets towards stronger material and also without offset. • The size of tunnel reduces significantly by increasing the plunge depth. • Tool pin offset towards weaker material prevent tunneling defects.

  7. Association analysis of polymorphism in KiSS1 gene with reproductive traits in goats.

    Science.gov (United States)

    El-Tarabany, Mahmoud S; Zaglool, Asmaa W; El-Tarabany, Akram A; Awad, Ashraf

    2017-05-01

    Understanding the genetic information of related genes is helpful for the selection and breeding course through marker assisted selection. The aim of the current study was to detect polymorphisms of the KiSS1 gene in 137 animals, including Baladi, Zaraibi and Damascus goat breeds by PCR-RFLP, and DNA sequencing and to investigate the association between these variants and reproductive traits. Comparison of the nucleotide sequence indicated the substitution of T with A at position 121 (T121A) in the intron 1 of the KiSS1 gene in all goat breeds. This substitution distorts the restriction site of the XmnI restriction enzyme and consequently two genotypes were detected (TA and TT). The T121A SNP is associated significantly with litter size in Damascus and Zaribi breeds (p=0.025 and 0.001, respectively). The animals with the TT genotype in Damascus and Zaribi breeds had a significantly higher estradiol 17β level than that recorded in TA genotype at estrus phase (p=0.013 and 0.028, respectively) and late-luteal phase (p=0.067 and 0.041, respectively) of the estrus cycle. Furthermore, animals with the TT genotype in Damascus and Zaribi breeds had significant higher progesterone level at mid-luteal (p=0.037 and 0.045, respectively) phase. Meanwhile, there were no significant differences in progesterone level in late-luteal phase between both genotypes in Zaribi breed (p=0.267). The current trial indicated that the prolific TT genotype in both Damascus and Zaribi breeds had superior estradiol 17β level at estrus phase and an eminent progesterone level at both early and mid-luteal phases of the estrous cycle. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Which factors play a role in Dutch health promotion professionals' decision to recruit actively primary schools to use a web-based smoking prevention programme?

    Science.gov (United States)

    Cremers, Henricus-Paul; Oenema, Anke; Mercken, Liesbeth; Candel, Math; de Vries, Hein

    2013-12-03

    Municipal Health Promotion Organisations (MHPOs) play an important role in promoting and disseminating prevention programmes, such as smoking prevention programmes, in schools. This study identifies factors that may facilitate or hinder MHPOs' willingness to recruit actively primary schools to use a smoking prevention programme. In 2011, 31 Dutch MHPOs were invited to recruit schools to use a smoking prevention programme. All MHPO employees involved in smoking prevention activities (n = 68) were asked to complete a questionnaire assessing psychological factors and characteristics of their organisation that might affect their decision to be involved in active recruitment of schools. T-tests and multivariate analysis of variance assessed potential differences in psychological and organisational factors between active and non-active recruiters. A total of 45 professionals returned the questionnaire (66.2%). Active recruiters (n = 12) had more positive attitudes (p = 0.02), higher self-efficacy expectations (p primary schools, compared with non-active recruiters. Organisational factors did not discriminate between active and non-active recruiters. Primarily psychological factors seem to be associated with MHPOs' decision to recruit schools actively. This indicates that creating more positive attitude, self-efficacy beliefs and formation of plans may help in getting more MHPOs involved in active recruitment procedures.

  9. Technology programme

    International Nuclear Information System (INIS)

    2007-01-01

    The technology activities carried out by the EURATOM-ENEA Association concern the continuation of the European Fusion Development Agreement (EFDA) as well as the ITER activities coordinated by the ITER International Office and Fusion for Energy. Also included in the activities are design and RD under the Broader Approach Agreement between the EU and Japan. In order to better contribute to the programme a number of consortium agreements among the Associations are being signed. Collaboration with industries in view of their participation in the construction of ITER was further strengthened, mainly in the field of magnet and divertor components. The new European Test Blanket Facility at ENEA Brasimone was completed; the design of the ITER radial neutron camera was optimised and the performance achievable with the in-vessel viewing system was further assessed by experimental trials. Design activities for the JT-60SA magnet and power supply system as well as the design and experimental activities related to the target of the International Fusion Materials Irradiation Facility were continued. Significant work was done to define quality assurance for neutronics analyses. Mockups of the ITER pre-compression ring made in glass fibre epoxy were tested. The activities and results documented in the following illustrate ENEA's efforts to support fusion development

  10. The WEST programme: Minimizing technology and operational risks of a full actively cooled tungsten divertor on ITER

    Energy Technology Data Exchange (ETDEWEB)

    Grosman, André, E-mail: andre.grosman@cea.fr [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Bucalossi, Jérôme; Doceul, Louis [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Escourbiac, Frédéric [ITER Organization, Cadarache, 13115 St. Paul-lez-Durance (France); Lipa, Manfred [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Merola, Mario [ITER Organization, Cadarache, 13115 St. Paul-lez-Durance (France); Missirlian, Marc [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Pitts, Richard A. [ITER Organization, Cadarache, 13115 St. Paul-lez-Durance (France); Samaille, Franck; Tsitrone, Emmanuelle [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France)

    2013-10-15

    Highlights: ► The WEST programme is a unique opportunity to experience the industrial scale manufacture of tungsten plasma-facing components similar to the ITER divertor ones. ► In Tore Supra, it will bring important know how for actively cooled W divertor operation. ► This can be done by a reasonable modification of the Tore Supra tokamak. ► A fast implementation of the project would make this information available in due time. ► This allows a significant contribution to the W ITER divertor risk minimization in its manufacturing and operation phase. -- Abstract: The WEST programme consists in transforming the Tore Supra tokamak into an X point divertor device, while taking advantage of its long discharge capability. This is obtained by inserting in vessel coils to create the X point while adapting the in-vessel elements to this new geometry. This will allow the full tungsten divertor technology to be used on ITER to be tested in anticipation of its use on ITER under relevant heat loading conditions and pulse duration. The early manufacturing of a significant industrial series of ITER-similar W plasma-facing units will contribute to the ITER divertor manufacturing risk mitigation and to that associated with early W divertor plasma operation on ITER.

  11. Effects of active non-smoking programmes on smoking behaviour in oral precancer patients.

    Science.gov (United States)

    Hamadah, O; Hepburn, S; Thomson, P J

    2007-08-01

    Smoking is the commonest risk factor for oral cancer and precancer. The objective of this study was to characterize smoking behaviour and attitude in a cohort of oral precancer patients in Newcastle upon Tyne, UK, and to determine changes in behaviour during diagnosis, treatment and follow-up. Twenty-seven consecutive, smoking patients with dysplastic oral lesions were recruited to the study and a detailed smoking history obtained, quantifying types and numbers of cigarettes smoked, length of smoking history, and changes in smoking behaviour during treatment episodes and long-term follow-up. All patients underwent an interventional management protocol comprising risk-factor education, histopathological diagnosis by incisional biopsy and laser excision of lesions. Patients were followed up for 5 years. Whilst there was a significant decrease in the number of cigarettes smoked at patients' most recent follow-up compared with initial presentation (p<0.001), 74% continued to smoke. Patients received advice from a smoking cessation adviser on support available to them from the local NHS (National Health Service) Stop Smoking services. Six out of 10 patients who set a 'quit date' and attended a programme had quit at the 4-week follow-up but only 5 remained non-smokers. Smoking remains a considerable problem in oral precancer patients even after interventional treatment, with the risk of further precancerous lesions and malignant transformation.

  12. Clinical outcomes after final kissing balloon inflation compared with no final kissing balloon inflation in bifurcation lesions treated with a dedicated coronary bifurcation stent.

    Science.gov (United States)

    Grundeken, Maik J; Lesiak, Maciej; Asgedom, Solomon; Garcia, Eulogio; Bethencourt, Armando; Norell, Michael S; Damman, Peter; Woudstra, Pier; Koch, Karel T; Vis, M Marije; Henriques, Jose P; Tijssen, Jan G; Onuma, Yoshinobu; Foley, David P; Bartorelli, Antonio L; Stella, Pieter R; de Winter, Robbert J; Wykrzykowska, Joanna J

    2014-03-01

    We evaluated differences in clinical outcomes between patients who underwent final kissing balloon inflation (FKBI) and patients who did not undergo FKBI in bifurcation treatment using the Tryton Side Branch Stent (Tryton Medical, Durham, North Carolina, USA). Clinical outcomes were defined as target vessel failure (composite of cardiac death, any myocardial infarction and clinically indicated target vessel revascularisation), cardiac death, myocardial infarction (MI), clinically indicated target vessel revascularisation and stent thrombosis. Cumulative event rates were estimated using the Kaplan-Meier method. A multivariable logistic regression analysis was performed to evaluate which factors were potentially associated with FKBI performance. Follow-up data was available in 717 (96%) patients with a median follow-up of 190 days. Cardiac death at 1 year occurred more often in the no-FKBI group (1.7% vs 4.6%, respectively, p=0.017), although this difference was no longer observed after excluding patients presenting with ST segment elevation MI (1.6% vs 3.3%, p=0.133). No significant differences were observed concerning the other clinical outcomes. One-year target vessel failure rates were 10.1% in the no-FKBI group and 9.2% in the FKBI group (p=0.257). Multivariable logistic regression analysis identified renal dysfunction, ST segment elevation MI as percutaneous coronary intervention indication, narrow (<30°) bifurcation angle and certain stent platforms as being independently associated with unsuccessful FKBI. A lower cardiac death rate was observed in patients in whom FKBI was performed compared with a selection of patients in whom FKBI could not be performed, probably explained by an unbalance in the baseline risk profile of the patients. No differences were observed regarding the other clinical outcomes.

  13. Molecular characterization of kiss2 and differential regulation of reproduction-related genes by sex steroids in the hypothalamus of half-smooth tongue sole (Cynoglossus semilaevis).

    Science.gov (United States)

    Wang, Bin; Liu, Quan; Liu, Xuezhou; Xu, Yongjiang; Song, Xuesong; Shi, Bao

    2017-11-01

    Kisspeptin (Kiss) plays a critical role in mediating gonadal steroid feedback to the gonadotropin-releasing hormone (GnRH) neurons in mammals. However, little information regarding the regulation of kisspeptin gene by sex steroids is available in teleosts. In this study, we examined the direct actions of estradiol (E2) and testosterone (T) on hypothalamic expression of kisspeptin and other key factors involved in reproductive function of half-smooth tongue sole. As a first step, a partial-length cDNA of kiss2 was identified from the brain of tongue sole and kiss2 transcript levels were shown to be widely expressed in various tissues, notably in the ovary. Then, the actions of sex steroids on kiss2 and other reproduction-related genes were evaluated using a primary hypothalamus culture system. Our results showed that neither kiss2 nor its receptor kiss2r mRNA levels were significantly altered by sex steroids. Moreover, sex steroids did not modify hypothalamic expression of gonadotropin-inhibitory hormone (gnih) and its receptor gnihr mRNAs, either. However, E2 markedly stimulated both gnrh2 and gnrh3 mRNAs levels. Overall, this study provides insights into the role of sex steroids in the reproductive function of Pleuronectiform teleosts. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. A Kiss Lajos-díj 2014. évi nyertese: dr. Slíz Mariann [The 2014 winner of Lajos Kiss Prize: Dr Mariann Slíz

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2014-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2014 winner of the prize is Dr Mariann Slíz, senior lecturer at the Department of Hungarian Linguistics and Finno-Ugric Studies of Eötvös Loránd University, Budapest. She earned this award for her contribution to Hungarian Onomastics, especially in research on personal names.

  15. A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2016-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

  16. Finnish bioenergy research programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D. [VTT Energy, Jyvaeskylae (Finland)

    1996-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  17. Finnish bioenergy research programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D [VTT Energy, Jyvaeskylae (Finland)

    1997-12-31

    Finland is a leading country in the use of biofuels and has excellent opportunities to increase the use of biofuels by up to 25-30 %. The Finnish Government has set an objective for the promotion of bioenergy. The aim is to increase the use of bioenergy by about 25 % from the present level by 2005, and the increment corresponds to 1.5 million tonnes of oil equivalent (toe) per year. The R and D work has been considered as an important factor to achieve this ambitious goal. Energy research was organised into a series of research programmes in 1988 in accordance with the proposal of Finnish Energy Research Committee. The object of the research programmes is to enhance research activities and to bundle individual projects together into larger research packages. The common target of the Finnish energy research programmes is to proceed from basic and applied research to product development and pilot operation, and after that to the first commercial applications, e.g. demonstrations. As the organisation of energy research to programmes has led to good results, the Finnish Ministry of Trade and Industry decided to go on with this practice by launching new six-year programmes in 1993-1998. One of these programmes is the Bioenergy Research Programme and the co-ordination of this programme is carried out by VTT Energy. Besides VTT Energy the Finnish Forest Research Institute, Work Efficiency Institute, Metsaeteho and University of Joensuu are participating in the programme 7 refs.

  18. An activity-based cost analysis of the Honduras community-based, integrated child care (AIN-C) programme.

    Science.gov (United States)

    Fiedler, John L; Villalobos, Carlos A; De Mattos, Annette C

    2008-11-01

    The Honduras AIN-C programme is a preventive health and nutrition programme of the Honduras Ministry of Health (MOH) that relies on volunteers to help mothers monitor and maintain the adequate growth of young children. A quasi-experimental, design-based evaluation found that the programme achieved near-universal coverage and was effective in improving mothers' child-rearing knowledge, attitudes and practices, including feeding and appropriate care-giving and care-seeking practices for children with diarrhoea and acute respiratory illness. The programme is widely regarded as a model. This study was undertaken to provide the first comprehensive estimates of the cost of the AIN-C programme, with the goal of providing a programme and financial planning tool for Honduras. An additional comparison of study findings was also undertaken to determine the cost of the AIN-C programme's community-based services relative to a similar facility-based service. Expressed in mid-2005 US dollars, the study found that after the programme is phased-in: (1) the annual, recurrent cost per child under 2 years participating in the programme is $6.43; (2) the annual, incremental budget requirements per child under 2 years participating in the programme are $3.90; (3) the cost of an AIN-C monthly growth monitoring and counselling session per child is 11% of the cost of a traditional MOH, facility-based growth and development consultation per child; and (4) the effect of mothers substituting AIN-C monitor care for MOH facility-based care 'saves' 203 000 outpatient visits a year, with a potential cost saving of $1.66 million, the equivalent of 60% of the recurrent cost of the programme and roughly equal to the annual incremental budget requirements of the programme. Sensitivity analysis of the cost estimates is performed to provide insight, for countries considering introducing a similar programme, into how modifications of key characteristics of the programme affect its costs.

  19. A structured physical activity and fitness programme for older adults with intellectual disabilities : Results of a cluster-randomised clinical trial

    NARCIS (Netherlands)

    van Schijndel-Speet, M.; Evenhuis, Heleen M.; van Wijck, R.; van Montfort, K. C. A. G. M.; Echteld, M. A.

    BackgroundThe physical activity level of older adults with intellectual disabilities (ID) is extremely low, and their fitness levels are far beneath accepted norms for older people with normal intelligence and comparable with frail older people. A physical activity programme, including an education

  20. Research activities on high-temperature gas-cooled reactors (HTRs) in the 5. EURATOM RTD Framework programme

    International Nuclear Information System (INIS)

    Martin-Bermejo, J.; Hugon, M.; Van Goethem, G.

    2002-01-01

    One of the areas of research of the 'nuclear fission' key action of the 5. EURATOM RTD Framework Programme (FP5) is the safety and efficiency of future systems. The main objective of this area is to investigate and evaluate new or revisited concepts (both reactors and alternative fuels) for nuclear energy that offer potential longer term benefits in terms of cost, safety, waste management, use of fissile material, less risk of diversion and sustainability. Several projects related to high-temperature gas-cooled reactors (HTRs) were retained by the European Commission (EC) services. They address important issues such as HTR fuel technology, HTR fuel cycle, HTR materials, power conversion systems and licensing. Most of these projects have already started and are progressing according to the schedule. They are the initial core of activities of a European Network on 'High-temperature Reactor Technology' (HTR-TN) recently set up by 18 EU organisations. (authors)

  1. Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice

    DEFF Research Database (Denmark)

    Overgaard, Agnete; Tena-Sempere, Manuel; Franceschini, Isabelle

    2013-01-01

    cells, only after axonal transport inhibition. Interestingly, the density of kisspeptin innervation in the anterior periventricular area was higher in female compared to male in both species. Species differences in the ARC were evident, with the mouse ARC containing dense fibers, while the rat ARC......-immunoreactivity in the mouse compared to the rat, independently of brain region and gender. In the female mouse AVPV high numbers of kisspeptin-immunoreactive neurons were present, while in the rat, the female AVPV displays a similar number of kisspeptin-immunoreactive neurons compared to the level of Kiss1 mRNA expressing...... contains clearly discernable cells. In addition, we show a marked sex difference in the ARC, with higher kisspeptin levels in females. These findings show that the translation of Kiss1 mRNA and/or the degradation/transportation/release of kisspeptins are different in mice and rats....

  2. "Kissing the crone": on a Slavic and pre-Slavic mythological figure

    Directory of Open Access Journals (Sweden)

    Katja Hrobat Virgolet

    2012-07-01

    Full Text Available The research focuses on the folklore regarding two monolith ‘Babas’ in the Karst region of Slovenia. From the Karst to the Vipava Valley and Croatian Istria, parents used the ‘baba’ to frighten their children, telling them that they would have to kiss or blow up the buttocks of the ugly ‘old baba’ (crone’ or swallow her snivel on their _rst visit to a neighbouring town (for example, Trieste. Throughout the area, stone ‘Babas’ were represented as personifications of a repulsive old woman. At Grobnik in Croatian Istria, a ‘Baba’ with pronounced female attributes is carved in rock at the entrance to the old town. In some parts, the imaginary or stone ‘Babas’ were given offerings of crops. At Golec in Cicarija, a three-day ritual to ‘Baba’ was performed on Midsummer Day, offering her water, soil and ashes (from a bonfire. Immolation and rituals performed in the immediate vicinity of ‘Babas’ are recorded also in Macedonia, as well as in France and Italy. The ‘Baba’ appears to be an omnipresent, yet fragmentarily preserved phenomenon in the traditions of all Slavic peoples. It encompasses different phenomena. On the one hand it represents old age, infertility, and on the other young, fertile things, or a structural support or basis. In Slavic traditions, the ‘baba’ is connected with water or equated with precipitation phenomena (rain, hail, places where storms break, etc.. She is associated with moisture through some adjectives (‘snotty’, ‘muddy’ or through the location of the stone monoliths by the water. According to the Rodik tradition, the ‘baba’s’ urine turns to rain, her fart to wind, and by lifting her skirt she brings clear weather. Slavic and Indo-European folklore material points to a close connection between bodily winds and conception, birth, and new souls. The lifting of the skirt is reminiscent of the obscene gesture by Baubó in Greek mythology. In several rituals of the Balkans

  3. Quantum backaction of optical observations on Bose-Einstein condensates by U. Leonhardt, T. Kiss, and P. Piwnicki

    Science.gov (United States)

    Ketterle, W.

    A recent paper, Quantum backaction of optical observations on Bose-Einstein condensates by U. Leonhardt, T. Kiss, and P. Piwnicki, Eur. Phys. J. D7, 413 (1999), emphasized that the limit of dispersive imaging of Bose-Einstein condensates with off-resonant light is not residual absorption, but a different form of quantum backaction of the probe light. This note points out that these conclusions are incorrect, and that Rayleigh scattering is the dominant quantum backaction of dispersive imaging.

  4. The I.A.G. / A.I.G. SEDIBUD (Sediment Budgets in Cold Environments) Programme: Current and future activities

    Science.gov (United States)

    Beylich, Achim A.; Lamoureux, Scott; Decaulne, Armelle

    2013-04-01

    Projected climate change in cold regions is expected to alter melt season duration and intensity, along with the number of extreme rainfall events, total annual precipitation and the balance between snowfall and rainfall. Similarly, changes to the thermal balance are expected to reduce the extent of permafrost and seasonal ground frost and increase active layer depths. These effects will undoubtedly change surface environments in cold regions and alter the fluxes of sediments, nutrients and solutes, but the absence of quantitative data and coordinated geomorphic process monitoring and analysis to understand the sensitivity of the Earth surface environment is acute in cold climate environments. The International Association of Geomorphologists (I.A.G. / A.I.G. ) SEDIBUD (Sediment Budgets in Cold Environments) Programme was formed in 2005 to address this existing key knowledge gap. SEDIBUD currently has about 400 members worldwide and the Steering Committee of this international programme is composed of ten scientists from eight different countries: Achim A. Beylich (Chair) (Norway), Armelle Decaulne (Secretary) (France), John C. Dixon (USA), Scott F. Lamoureux (Vice-Chair) (Canada), John F. Orwin (Canada), Jan-Christoph Otto (Austria), Irina Overeem (USA), Thorsteinn Sæmundsson (Iceland), Jeff Warburton (UK) and Zbigniew Zwolinski (Poland). The central research question of this global group of scientists is to: Assess and model the contemporary sedimentary fluxes in cold climates, with emphasis on both particulate and dissolved components. Initially formed as European Science Foundation (ESF) Network SEDIFLUX (Sedimentary Source-to-Sink Fluxes in Cold Environments) (2004 - ), SEDIBUD has further expanded to a global group of researchers with field research sites located in polar and alpine regions in the northern and southern hemisphere. Research carried out at each of the close to 50 defined SEDIBUD key test sites varies by programme, logistics and available

  5. Active lifestyle all your life : a multifactorial group-based falls-prevention programme

    OpenAIRE

    Johansson, Erika

    2015-01-01

    Internationally, gerontology focuses on an emerging paradigm of healthy ageing where the goal is to extend the senior years in absence of morbidity by improving human health. A major threat to healthy ageing is accidental falls, as falls are the second-leading cause of unintentional injury or deaths worldwide. For the individual who falls, it is crucial to be able to continue living an active, independent life in one’s senior years. Additionally social engagement, valued activities, as well a...

  6. Novel FGFR1 and KISS1R Mutations in Chinese Kallmann Syndrome Males with Cleft Lip/Palate

    Directory of Open Access Journals (Sweden)

    Hao Xu

    2015-01-01

    Full Text Available Kallmann syndrome (KS is characterized by isolated hypogonadotropic hypogonadism (IHH with anosmia and is sometimes associated with cleft lip/palate (CLP. In order to describe the clinical features, genetic etiology, and treatment outcome of KS males with CLP, we performed genetic screening for 15 known causal IHH genes (KAL1, FGFR1, NELF, FGF8, CHD7, WDR11, SEMA3A, KISS1R, KISS1, PROKR2, PROK2, TAC3, TACR3, GNRH1, and GNRHR in four KS with CLP patients and six IHH patients without CLP. Two novel heterozygous missense mutations in FGFR1, (NM_001174066: c.776G>A (p.G259E and (NM_001174066: c.358C>T (p.R120C, were identified in a 23-year-old KS male with cleft lip and an 18-year-old KS patient with cleft lip and palate, dental agenesis, and high arched palate, respectively. These two mutations were not presented in their healthy parents and 200 normal controls. One novel heterozygous missense mutation in KISS1R, (NM_032551: c.587C>A (p.P196H, was identified in an 18-year-old KS male with cleft lip and dental agenesis who developed sperm after being treated with gonadotropin. This mutation was also presented in his healthy father and grandfather. These results have implications for the diagnosis, genetic counseling, and treatment of KS and CLP males with mutations in FGFR1 gene.

  7. The ACIGA data analysis programme

    International Nuclear Information System (INIS)

    Scott, Susan M; Searle, Antony C; Cusack, Benedict J; McClelland, David E

    2004-01-01

    The data analysis programme of the Australian Consortium for Interferometric Gravitational Astronomy (ACIGA) was set up in 1998 by Scott to complement the then existing ACIGA programmes working on suspension systems, lasers and optics and detector configurations. The ACIGA data analysis programme continues to contribute significantly in the field; we present an overview of our activities

  8. Predictors of long-term change of a physical activity promotion programme in primary care.

    Science.gov (United States)

    Sanchez, Alvaro; Grandes, Gonzalo; Ortega Sánchez-Pinilla, Ricardo; Torcal, Jesus; Montoya, Imanol

    2014-02-04

    Further research is needed to improve the evidence regarding determinants of physical activity (PA) as a crucial step to plan higher effective intervention strategies. The goal of the present study is to identify socio-demographic and clinical characteristics of primary care (PHC) insufficiently active patients that are associated with longitudinal changes in the level of physical activity. Longitudinal analysis of baseline socio-demographic and clinical predictors of physical activity change in insufficiently active PHC patients who participated in a PA-promoting multi-centre randomized clinical trial conducted from October 2003 through March 2006. The primary outcome measure was the self-reported physical activity assessed with the 7-day Physical Activity Recall (PAR), at baseline, 6, 12 and 24 months. Baseline covariates included sex, age, social class, anthropometric measures and other cardiovascular risk factors or associated diseases (Diabetes, HTA, tobacco use, etc.), and stage of readiness to change PA. Generalized linear mixed models were used to estimate longitudinal association of studied variables on PA change over the three follow-up measurements. A total of 3691 patients (85% of the 4317 recruited in the trial) with at least one follow-up measurement were included in the longitudinal analysis. At baseline, analysed patients (mean age: 50.6 years; 64.6% women) devoted 34.7 minutes and 2.36 metabolic equivalent hours per week (MET.h/week) to moderate and vigorous physical activity. Older age, male gender, higher social class, lower BMI, diagnosis of diabetes or hypertension, and measurement season were significant predictors of PA longitudinal change. The effect of baseline readiness to change on PA dose was modified by time, showing a positive gradient in favour of those with more readiness to change that increases significantly at 12 and 24 months (p-value interaction < .0001). Identified baseline characteristics such as readiness to change and

  9. European Identity through Space Space Activities and Programmes as a Tool to Reinvigorate the European Identity

    CERN Document Server

    Baranes, Blandina

    2013-01-01

    Space activities are one particularly visible area, where Europe can shape its identity. This publication investigates the effect space activities have already had on building a European “spirit” (e.g. through European missions or European astronauts). It also looks into the effects that activities labelled “national” have on the emergence of a European identity. Based on this analysis, the book's intention is to identify creative ways and means for how to further use space for shaping the European identity. For this purpose the focus is not only on policy analysis but also on expertise from the fields of cultural science and the arts in order to tap their creative potential and also their theoretical approaches to the topic. Selecting this theme provides ESPI with another opportunity to develop its trans-disciplinary approach.

  10. The impact of a 10-week physical activity intervention programme on ...

    African Journals Online (AJOL)

    The purpose of this study was to determine the effects of a 10-week physical activity (PA) intervention on selective metabolic syndrome markers in black adolescents. All available adolescents (194 subjects), boys and girls, in the grade 9 class (15-19 years) attending a secondary school were recruited for the experimental ...

  11. Positive Youth Development through an Outdoor Physical Activity Programme: Evidence from a Four-Year Evaluation

    Science.gov (United States)

    Armour, Kathleen; Sandford, Rachel

    2013-01-01

    In 2006, Sandford, Armour and Warmington undertook a comprehensive review of the literature on the role of physical activity/sport and physical education in promoting positive development for disaffected youth. This paper revisits the findings of the literature review in light of data from a four-year evaluation of one corporate-sponsored physical…

  12. Delivering Sustainable Practice? A Case Study of the Scottish Active Schools Programme

    Science.gov (United States)

    Reid, Gavin

    2009-01-01

    Since 1999, concerns about Scotland's future health and economic performance have profoundly impacted on the new Scottish Executive. Research highlighting an obesity crisis facing young Scots has, together with the work of Scotland's Physical Activity Task Force and Physical Education Review Group, encouraged the education of all young Scots to be…

  13. Developmental programming of energy balance regulation: is physical activity more 'programmable' than food intake?

    Science.gov (United States)

    Zhu, Shaoyu; Eclarinal, Jesse; Baker, Maria S; Li, Ge; Waterland, Robert A

    2016-02-01

    Extensive human and animal model data show that environmental influences during critical periods of prenatal and early postnatal development can cause persistent alterations in energy balance regulation. Although a potentially important factor in the worldwide obesity epidemic, the fundamental mechanisms underlying such developmental programming of energy balance are poorly understood, limiting our ability to intervene. Most studies of developmental programming of energy balance have focused on persistent alterations in the regulation of energy intake; energy expenditure has been relatively underemphasised. In particular, very few studies have evaluated developmental programming of physical activity. The aim of this review is to summarise recent evidence that early environment may have a profound impact on establishment of individual propensity for physical activity. Recently, we characterised two different mouse models of developmental programming of obesity; one models fetal growth restriction followed by catch-up growth, and the other models early postnatal overnutrition. In both studies, we observed alterations in body-weight regulation that persisted to adulthood, but no group differences in food intake. Rather, in both cases, programming of energy balance appeared to be due to persistent alterations in energy expenditure and spontaneous physical activity (SPA). These effects were stronger in female offspring. We are currently exploring the hypothesis that developmental programming of SPA occurs via induced sex-specific alterations in epigenetic regulation in the hypothalamus and other regions of the central nervous system. We will summarise the current progress towards testing this hypothesis. Early environmental influences on establishment of physical activity are likely an important factor in developmental programming of energy balance. Understanding the fundamental underlying mechanisms in appropriate animal models will help determine whether early life

  14. IAEA activities in support of the international programmes to return fresh and spent research reactor nuclear fuel to the conuntry of origin

    International Nuclear Information System (INIS)

    Adelgang, P.; Tozser, S.; Marshall, F.; Borio di Tigliole, A.

    2017-01-01

    The IAEA has been involved for more than thirty years in supporting international nuclear non-proliferation efforts associated with reducing the amount of Highly Enriched Uranium (HEU), whose enrichment is ≥ 20% in 235U, in international commerce. In particular, IAEA projects and activities have directly supported the two main international efforts to return fresh and spent HEU research reactor fuel to the country where it was originally enriched: the United States Foreign Research Reactor Spent Nuclear Fuel (FRRSNF) Acceptance Programme and the United States-IAEA-Russian Federation tripartite initiative known as the Russian Research Reactor Fuel Return (RRRFR) Programme. This report gives an account of IAEA efforts in support of both programmes including a historical overview of fuel return shipments and a brief description of associated cooperation activities carried out by the IAEA. [es

  15. Piloting a programme tool to evaluate malaria case investigation and reactive case detection activities: results from 3 settings in the Asia Pacific.

    Science.gov (United States)

    Cotter, Chris; Sudathip, Prayuth; Herdiana, Herdiana; Cao, Yuanyuan; Liu, Yaobao; Luo, Alex; Ranasinghe, Neil; Bennett, Adam; Cao, Jun; Gosling, Roly D

    2017-08-22

    Case investigation and reactive case detection (RACD) activities are widely-used in low transmission settings to determine the suspected origin of infection and identify and treat malaria infections nearby to the index patient household. Case investigation and RACD activities are time and resource intensive, include methodologies that vary across eliminating settings, and have no standardized metrics or tools available to monitor and evaluate them. In response to this gap, a simple programme tool was developed for monitoring and evaluating (M&E) RACD activities and piloted by national malaria programmes. During the development phase, four modules of the RACD M&E tool were created to assess and evaluate key case investigation and RACD activities and costs. A pilot phase was then carried out by programme implementers between 2013 and 2015, during which malaria surveillance teams in three different settings (China, Indonesia, Thailand) piloted the tool over a period of 3 months each. This study describes summary results of the pilots and feasibility and impact of the tool on programmes. All three study areas implemented the RACD M&E tool modules, and pilot users reported the tool and evaluation process were helpful to identify gaps in RACD programme activities. In the 45 health facilities evaluated, 71.8% (97/135; min 35.3-max 100.0%) of the proper notification and reporting forms and 20.0% (27/135; min 0.0-max 100.0%) of standard operating procedures (SOPs) were available to support malaria elimination activities. The tool highlighted gaps in reporting key data indicators on the completeness for malaria case reporting (98.8%; min 93.3-max 100.0%), case investigations (65.6%; min 61.8-max 78.4%) and RACD activities (70.0%; min 64.7-max 100.0%). Evaluation of the SOPs showed that knowledge and practices of malaria personnel varied within and between study areas. Average monthly costs for conducting case investigation and RACD activities showed variation between study

  16. Strategies to improve the implementation of healthy eating, physical activity and obesity prevention policies, practices or programmes within childcare services.

    Science.gov (United States)

    Wolfenden, Luke; Jones, Jannah; Williams, Christopher M; Finch, Meghan; Wyse, Rebecca J; Kingsland, Melanie; Tzelepis, Flora; Wiggers, John; Williams, Amanda J; Seward, Kirsty; Small, Tameka; Welch, Vivian; Booth, Debbie; Yoong, Sze Lin

    2016-10-04

    Despite the existence of effective interventions and best-practice guideline recommendations for childcare services to implement policies, practices and programmes to promote child healthy eating, physical activity and prevent unhealthy weight gain, many services fail to do so. The primary aim of the review was to examine the effectiveness of strategies aimed at improving the implementation of policies, practices or programmes by childcare services that promote child healthy eating, physical activity and/or obesity prevention. The secondary aims of the review were to:1. describe the impact of such strategies on childcare service staff knowledge, skills or attitudes;2. describe the cost or cost-effectiveness of such strategies;3. describe any adverse effects of such strategies on childcare services, service staff or children;4. examine the effect of such strategies on child diet, physical activity or weight status. We searched the following electronic databases on 3 August 2015: the Cochrane Central Register of Controlled trials (CENTRAL), MEDLINE, MEDLINE In Process, EMBASE, PsycINFO, ERIC, CINAHL and SCOPUS. We also searched reference lists of included trials, handsearched two international implementation science journals and searched the World Health Organization International Clinical Trials Registry Platform (www.who.int/ictrp/) and ClinicalTrials.gov (www.clinicaltrials.gov). We included any study (randomised or non-randomised) with a parallel control group that compared any strategy to improve the implementation of a healthy eating, physical activity or obesity prevention policy, practice or programme by staff of centre-based childcare services to no intervention, 'usual' practice or an alternative strategy. The review authors independently screened abstracts and titles, extracted trial data and assessed risk of bias in pairs; we resolved discrepancies via consensus. Heterogeneity across studies precluded pooling of data and undertaking quantitative

  17. Development of a training programme for home health care workers to promote preventive activities focused on a healthy lifestyle: an intervention mapping approach.

    Science.gov (United States)

    Walters, Maaike E; Dijkstra, Arie; de Winter, Andrea F; Reijneveld, Sijmen A

    2015-07-09

    Lifestyle is an important aspect in maintaining good health in older adults, and home health care (HHC) workers can play an important role in promoting a healthy lifestyle. However, there is limited evidence in the literature regarding how to develop an effective training programme to improve the physical activity level and fruit and vegetable consumption of older adults within a HHC setting. The aim of this paper is to describe how Intervention Mapping (IM) was used to develop a training programme to promote preventive activities of HHC workers relating to the physical activity and fruit and vegetable intake of older adults living at home. IM, a systematic theory and evidence-based approach was used to develop, implement and evaluate the training programme. This entailed a literature search, a survey, semi-structured interviews and consultation with HHC workers and various field experts, and a pilot training session. The determinants associated with the provision of preventive activities were identified, and an overview was created of those objectives, matching methods and practical applications that could influence these determinants. The performance objectives for the HHC workers were early detection and monitoring, promoting a healthy lifestyle, informing colleagues, continuing allocated preventive activities and referring to other experts and facilities. Findings were translated into a comprehensive training programme for HHC workers focused on motivating older adults to adopt and maintain a healthier lifestyle. IM was a useful tool in the development of a theory-based training programme to promote preventive activities by HHC workers relating to fruit and vegetable intake and physical activity of older adults.

  18. Proposed development programme for a temporary containment system for alpha active decommissioning

    International Nuclear Information System (INIS)

    Pengelly, M.G.A.; Burnett, R.C.

    1983-06-01

    This report makes a proposal to design, develop and test a containment of modular construction under plutonium active conditions. While this proposal contemplates work with plutonium, the system, when fully developed, has obvious applications wherever a temporary containment of radioactive or toxic materials is required. The fundamental feature of the proposal is that strippable coatings are used to prevent the inner surfaces of the working area from becoming contaminated. It is envisaged that this method of protecting the surfaces will enable the modular containment structure to be disassembled and re-used. (author)

  19. Forecasting inclusion of active population in programmes of non/formal education

    Directory of Open Access Journals (Sweden)

    Jasmina Mirčeva

    2015-01-01

    Full Text Available This paper deals with the issue of inclusion of the active population in formal and non-formal education in Slovenia. It also examines factors that influence this participation in either positive or negative way and indicates statistical models of educational inclusion. The approach stems from the current state of development of economy and society in European countries, where the economic crisis and recession has led to a fall in GDP, lower economic growth, increase in unemployment (especially in young population and a decline in the quality of life and labour.

  20. The Effectiveness of a Cricket Programme for Engaging People with a Disability in Physical Activity in Fiji

    Science.gov (United States)

    Beckman, Emma; Rossi, Tony; Hanrahan, Stephanie; Rynne, Steven; Dorovolomo, Jeremy

    2018-01-01

    Sport has been demonstrably linked to health particularly through community-based education and development programmes. However, research continues to identify low participation rates of people with a disability in sport. Programmes to address the participation of people with a disability in sport can be challenging, particularly in locations in…

  1. Neutron activation analysis of pollutants in human hair using research reactors. Part of a coordinated programme

    International Nuclear Information System (INIS)

    Al-Shahristani, H.I.

    1978-02-01

    Hair is a suitable indicator of man's exposure to trace element environmental pollutants. Bearing this in mind, two hundred and fifty human head hair samples were randomly collected from various regions of Iraq representing the general population. These elements were analyzed by thermal neutron activation analysis and the following elements were instrumentally determined: Cr, Fe, Co, Ni, Zn, As, Se, Br, Ag, Cd, Sb, La, Au, Hg, Th and U. The arithmetic mean, geometric mean, standard deviation and range of concentration of these elements and the frequency distributions within the population are given and compared with concentrations from other regions of the world. In general the concentrations determined for this population are similar to those reported for other areas except for Br and Fe. The possible causes of these anomalies are discussed. For certain population sub-groups, high levels of Au, Ag, Cr, Se and Hg have been measured and the reasons for these deviations are discussed

  2. Bio-optofluidics and Bio-photonics: Programmable Phase Optics activities at DTU Fotonik

    DEFF Research Database (Denmark)

    Bañas, Andrew Rafael; Palima, Darwin; Pedersen, Finn

    We present ongoing research and development activities for constructing a compact next generation BioPhotonics Workstation and a Bio-optofluidic Cell Sorter (cell-BOCS) for all-optical micromanipulation platforms utilizing low numerical aperture beam geometries. Unlike conventional high NA optical...... tweezers, the BioPhotonics workstation is e.g. capable of long range 3D manipulation. This enables a variety of biological studies such as manipulation of intricate microfabricated assemblies or for automated and parallel optofluidic cell sorting. To further reduce its overhead, we propose ways of making...... the BioPhotonics Workstation platform more photon efficient by studying the 3D distribution of the counter propagating beams and utilizing the Generalized Phase Contrast (GPC) method for illuminating the applied spatial light modulators....

  3. The role of type of activity in parent–child interactions within a family literacy programme: comparing prompting boards and shared reading

    NARCIS (Netherlands)

    S. de la Rie; Dr. A.J.S. van Gelderen; R.C.M. van Steensel

    2016-01-01

    To examine what kinds of parent–child interactions are elicited by different literacy-related activities, an exploratory study was conducted with 19 mother–child dyads. Although prompting boards are widely incorporated in pre- and primary school curricula, and in various family literacy programmes,

  4. Cost-effectiveness of a long-term Internet-delivered worksite health promotion programme on physical activity and nutrition: A cluster randomized controlled trial

    NARCIS (Netherlands)

    S.J.W. Robroek (Suzan); S. Polinder (Suzanne); F.J. Bredt (Folef); A. Burdorf (Alex)

    2012-01-01

    textabstractThis study aims to evaluate the cost-effectiveness of a long-term workplace health promotion programme on physical activity (PA) and nutrition. In total, 924 participants enrolled in a 2-year cluster randomized controlled trial, with departments (n = 74) within companies (n = 6) as the

  5. Design of a process evaluation of the implementation of a physical activity and sports stimulation programme in Dutch rehabilitation setting : ReSpAct

    NARCIS (Netherlands)

    Hoekstra, Femke; Alingh, Roelina; van der Schans, Cees; Hettinga, Florentina; Duijff, Marjo; Dekker, Rienk; van der Woude, Lucas H.V.

    2014-01-01

    Background There is a growing interest to study the transfer of evidence-based information into daily practice. The evidence-based programme Rehabilitation, Sports and Exercise (RSE) that aims to stimulate an active lifestyle during and after a rehabilitation period in people with a disability

  6. Systematic review on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity

    NARCIS (Netherlands)

    Dongen, J.M. van; Proper, K.I.; Wier, M.F. van; Beek, A.J. van der; Bongers, P.M.; Mechelen, W. van; Tulder, M.W. van

    2011-01-01

    Summary: This systematic review summarizes the current evidence on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity. Data on study characteristics and results were extracted from 18 studies published up to 14 January 2011.

  7. Cost-Effectiveness of a Long-Term Internet-Delivered Worksite Health Promotion Programme on Physical Activity and Nutrition: A Cluster Randomized Controlled Trial

    Science.gov (United States)

    Robroek, Suzan J. W.; Polinder, Suzanne; Bredt, Folef J.; Burdorf, Alex

    2012-01-01

    This study aims to evaluate the cost-effectiveness of a long-term workplace health promotion programme on physical activity (PA) and nutrition. In total, 924 participants enrolled in a 2-year cluster randomized controlled trial, with departments (n = 74) within companies (n = 6) as the unit of randomization. The intervention was compared with a…

  8. Improved cognitive performance in preadolescent Danish children after the school-based physical activity programme "FIFA 11 for Health" for Europe - A cluster-randomised controlled trial.

    Science.gov (United States)

    Lind, Rune Rasmussen; Geertsen, Svend Sparre; Ørntoft, Christina; Madsen, Mads; Larsen, Malte Nejst; Dvorak, Jiri; Ritz, Christian; Krustrup, Peter

    2018-02-01

    Recent studies have shown promising effects of physical activity on cognitive function, but there is a need to investigate this link in real-life settings such as schools. Hence, the objective of the present pilot study was to investigate whether the school-based physical activity programme "FIFA 11 for Health" for Europe could improve cognitive performance in preadolescent Danish children. The pilot study used an 11-week cluster-randomised intervention study design. School classes were randomly assigned to either a control group (CG) (n = 93 children, age = 11.8, s = 0.2 years), which performed the obligatory daily school-based physical activity (5 × 45 minutes per week); or an intervention group (IG) (n = 838 children, age = 11.9, s = 0.4 years), which substituted 2 × 45 minutes per week of the daily school physical activity with the "FIFA 11 for Health" for Europe programme. The programme combines small-sided football games, drills and health education. Cognitive performance was evaluated at baseline and follow-up. The IG improved their cognitive performance compared to the CG for psychomotor function (56, s x -  = 22 ms, p school-based physical activity programme "FIFA 11 for Health" for Europe can improve cognitive performance in preadolescent Danish schoolchildren. Future studies should attempt to disentangle the effects of "FIFA 11 for Health" for Europe on cognitive performance by investigating the characteristics of the programme's physical activity.

  9. International Atomic Energy Agency programme and activity on the utilization of low energy accelerators

    International Nuclear Information System (INIS)

    Shalnov, A.V.; Whetstone, S.L.

    1974-01-01

    One of the chief missions of the Agency is as intermediary between the more highly developed of its member states and the less developed. This involves transmittal of needs of the latter to the former and, where possible, in response to the needs, an appropriate transfer of information and technical assistance. The physics section of the IAEA has recently encouraged and supported requests for technical assistance for programs based on neutron activation studies or pedagogic neutron physics experiments for institutes entering the nuclear field. Neutron generator laboratories have been set up with IAEA-assistance most recently in Burma, Hong Kong, Lebanon. Other recent technical assistance projects involving low-energy accelerators include: (1) consultation on the future program for the accelerator laboratory in Algeria; (2) equipment and experts to assist the nuclear physics program at the Van de Graaff in Bangladesh; (3) expert assistance and equipment in support of the installation of an electron linear accelerator in Egypt; and (4) expert assistance for nuclear physics studies at the cyclotron in Chile. A large number of young scientists, particularly from S.E. Europe, but also from the Middle East and South America, have received training in nuclear physics experimentation by advanced countries at low energy accelerator laboratories under the IAEA fellowship program

  10. The Role of Kiss1 Neurons As Integrators of Endocrine, Metabolic, and Environmental Factors in the Hypothalamic–Pituitary–Gonadal Axis

    Directory of Open Access Journals (Sweden)

    Shel-Hwa Yeo

    2018-04-01

    Full Text Available Kisspeptin–GPR54 signaling in the hypothalamus is required for reproduction and fertility in mammals. Kiss1 neurons are key regulators of gonadotropin-releasing hormone (GnRH release and modulation of the hypothalamic–pituitary–gonadal (HPG axis. Arcuate Kiss1 neurons project to GnRH nerve terminals in the median eminence, orchestrating the pulsatile secretion of luteinizing hormone (LH through the intricate interaction between GnRH pulse frequency and the pituitary gonadotrophs. Arcuate Kiss1 neurons, also known as KNDy neurons in rodents and ruminants because of their co-expression of neurokinin B and dynorphin represent an ideal hub to receive afferent inputs from other brain regions in response to physiological and environmental changes, which can regulate the HPG axis. This review will focus on studies performed primarily in rodent and ruminant species to explore potential afferent inputs to Kiss1 neurons with emphasis on the arcuate region but also considering the rostral periventricular region of the third ventricle (RP3V. Specifically, we will discuss how these inputs can be modulated by hormonal, metabolic, and environmental factors to control gonadotropin secretion and fertility. We also summarize the methods and techniques that can be used to study functional inputs into Kiss1 neurons.

  11. Activating welfare recipients with health complaints: Reasons for failure of a cognitive training programme

    Directory of Open Access Journals (Sweden)

    Inge Bramsen

    2011-03-01

    Een groeiende nadruk op de activering van uitkeringsgerechtigden heeft in veel Westerse verzorgingsstaten geleid tot de ontwikkeling van interventies die gericht zijn op uitkeringsgerechtigden met gezondheidsklachten. Vormen van dwang, zoals verplichte participatie, worden meer en meer toegepast binnen dit activeringsbeleid. Een voorbeeld hiervan is het Nederlandse project “Gezond aan de Slag”, dat een interventie ontwikkelde en evalueerde waarin een fysiek trainingsprogramma gecombineerd wordt met cognitieve training. Hoewel HtW als “best practice” gold, liet een randomized trial geen positieve effecten van de interventie zien. Omdat het cognitieve trainingsprogramma, gebaseerd op rationeel-emotieve therapie, niet eerder afzonderlijk werd bestudeerd, werd een diepgaande kwalitatieve studie uitgevoerd. Getracht werd om de oorzaken van het falen van het programma in kaart te brengen. Zes, gericht geselecteerde, trainers werden geïnterviewd. De resultaten lieten zien dat de trainers problemen hadden met de heterogeniteit van de deelnemersgroep en op andere problemen, verwachtingen en arbeidsmarktobstakels stuitten dan vooraf verwacht. De verplichte aard van HtW had een negatief effect op de motivatie van zowel deelnemers als trainers. In de discussieparagraaf van dit artikel worden vraagtekens geplaatst bij de veronderstelling dat de coping stijl en cognities van uitkeringsgerechtigden met gezondheidsproblemen de belangrijkste hindernissen zijn voor het vinden van werk, en worden vraagtekens geplaatst bij het beleid om fysieke beperkingen van deelnemers te negeren. De auteurs suggereren dat met betrekking tot dit complexe praktijkprobleem, verbetering kan worden bereikt door aanpassen en leren van de interventie gedurende de toepassing daarvan toe te staan, en door expliciet te reflecteren op de normatieve aspecten van de interventie, en de perspectieven van de uitkeringsgerechtigden zelf.

  12. Improved cognitive performance in preadolescent Danish children after the school-based physical activity programme "FIFA 11 for Health" for Europe

    DEFF Research Database (Denmark)

    Lind, Rune Rasmussen; Geertsen, Svend Sparre; Ørntoft, Christina Øyangen

    2018-01-01

    , p = .012) and working memory (79, sx– = 35 ms, p = .020). Conclusion: This pilot study provides evidence that the school-based physical activity programme “FIFA 11 for Health” for Europe can improve cognitive performance in preadolescent Danish schoolchildren. Future studies should attempt...... programme. The programme combines small-sided football games, drills and health education. Cognitive performance was evaluated at baseline and follow-up. Results: The IG improved their cognitive performance compared to the CG for psychomotor function (56, sx– = 22 ms, p attention (39, sx– = 17 ms...

  13. Crispv programme

    International Nuclear Information System (INIS)

    Marinkovicj, N.

    CRISPV (Criticality and Spectrum code) is a multigroup neutron spectrum code for homogeneous reactor cores and is actually a somewhat modified version of the original CRISP programme. It is a combination of DATAPREP-II and BIGG-II programmes. It is assumed that the reactor cell is a cylindrical fuel rod in the light or heavy water moderator. DATEPREP-II CODE forms the multigroup data for homogeneous reactor and prepares the input parameters for the BIGG-II code. It has its own nuclear data library on a separate tape in binary mode. BIGG-II code is a multigroup neutron spectrum and criticality code for a homogenized medium. It has as well its own separate data library. In the CRISPV programme the overlay structure enables automatic handling of data calculated in the DATAPREP-II programme and needed in the BIGG-II core. Both programmes are written in FORTRAN for CDC 3600. Using the programme is very efficient and simple

  14. Intervention dose estimation in health promotion programmes: a framework and a tool. Application to the diet and physical activity promotion PRALIMAP trial

    Directory of Open Access Journals (Sweden)

    Legrand Karine

    2012-09-01

    Full Text Available Abstract Background Although the outcomes of health promotion and prevention programmes may depend on the level of intervention, studies and trials often fail to take it into account. The objective of this work was to develop a framework within which to consider the implementation of interventions, and to propose a tool with which to measure the quantity and the quality of activities, whether planned or not, relevant to the intervention under investigation. The framework and the tool were applied to data from the diet and physical activity promotion PRALIMAP trial. Methods A framework allowing for calculation of an intervention dose in any health promotion programme was developed. A literature reviews revealed several relevant concepts that were considered in greater detail by a multidisciplinary working group. A method was devised with which to calculate the dose of intervention planned and that is actually received (programme-driven activities dose, as well as the amount of non-planned intervention (non-programme-driven activities dose. Results Indicators cover the roles of all those involved (supervisors, anchor personnel as receivers and providers, targets, in each intervention-related groups (IRG: basic setting in which a given intervention is planned by the programme and may differ in implementation level and for every intervention period. All indicators are described according to two domains (delivery, participation in two declensions (quantity and quality. Application to PRALIMAP data revealed important inter- and intra-IRG variability in intervention dose. Conclusions A literature analysis shows that the terminology in this area is not yet consolidated and that research is ongoing. The present work provides a methodological framework by specifying concepts, by defining new constructs and by developing multiple information synthesis methods which must be introduced from the programme's conception. Application to PRALIMAP underlined the

  15. Greek Teachers Programme 2015

    CERN Multimedia

    Hoch, Michael

    2015-01-01

    The 3rd edition of this year's Greek Teachers Programme was co-organized by CERN Education Group and the Hellenic Physical Society and took place from 8 to 12 November 2015. The programme targets physics high-school teachers from all over Greece. It aims to help teachers inspire the next generation of scientists and engineers by motivating their students to understand and appreciate how science works at the world's largest physics laboratory, whereby increasing their interest in pursuing studies in STEM fields in secondary and post-secondary education. 33 teachers took part in this programme which comprised lectures by Greek members of the CERN scientific community, with visits to experimental facilities, hands-on activities and dedicated sessions on effective and creative ways through which participants may bring physics, particle physics and CERN closer to their school classroom. In 2015, more than 100 teachers took part in the three editions of the Greek Teachers Programme.

  16. The French energy programme

    International Nuclear Information System (INIS)

    Bohnen, U.

    1980-01-01

    The challenge of the oil crisis made French energy policy react chiefly by means of a programme for the rapid expansion of nuclear energy which has become unparalleled because of its systematic realization. The following article gives a survey of this programme and its political preconditions. The French energy programme deserves special attention as the utilization of nuclear energy in France including all related activities has reached a more advanced stage than in most other countries. The effects and requirements connected with such an extensive programme which can therefore be investigated with the help of the French example migth be of importance also for other countries in a similar way. (orig./UA) [de

  17. VIP in construction: systematic development and evaluation of a multifaceted health programme aiming to improve physical activity levels and dietary patterns among construction workers

    Directory of Open Access Journals (Sweden)

    Viester Laura

    2012-01-01

    Full Text Available Abstract Background The prevalence of both overweight and musculoskeletal disorders (MSD in the construction industry is high. Many interventions in the occupational setting aim at the prevention and reduction of these health problems, but it is still unclear how these programmes should be designed. To determine the effectiveness of interventions on these health outcomes randomised controlled trials (RCTs are needed. The aim of this study is to systematically develop a tailored intervention for prevention and reduction of overweight and MSD among construction workers and to describe the evaluation study regarding its (cost-effectiveness. Methods/Design The Intervention Mapping (IM protocol was applied to develop and implement a tailored programme aimed at the prevention and reduction of overweight and MSD. The (cost- effectiveness of the intervention programme will be evaluated using an RCT. Furthermore, a process evaluation will be conducted. The research population will consist of blue collar workers of a large construction company in the Netherlands. Intervention The intervention programme will be aimed at improving (vigorous physical activity levels and healthy dietary behaviour and will consist of tailored information, face-to-face and telephone counselling, training instruction (a fitness "card" to be used for exercises, and materials designed for the intervention (overview of the company health promoting facilities, waist circumference measuring tape, pedometer, BMI card, calorie guide, recipes, and knowledge test. Main study parameters/endpoints The intervention effect on body weight and waist circumference (primary outcome measures, as well as on lifestyle behaviour, MSD, fitness, CVD risk indicators, and work-related outcomes (i.e. productivity, sick leave (secondary outcome measures will be assessed. Discussion The development of the VIP in construction intervention led to a health programme tailored to the needs of construction

  18. Development and feasibility testing of an intervention to support active lifestyles in youths with type 1 diabetes-the ActivPals programme: a study protocol.

    Science.gov (United States)

    Mitchell, Fiona; Kirk, Alison; Robertson, Kenneth; Reilly, John J

    2016-01-01

    The global incidence of type 1 diabetes is rising, and youths with type 1 diabetes continue to suffer poorer health than peers without diabetes. Evidence suggests youths with type 1 diabetes have physical activity (PA) levels well below the recommendations for health and have high levels of sedentary behaviour. An active lifestyle is therefore recommended to improve health. There is limited research showing effective lifestyle behaviour change in this population; therefore, an evidence gap exists between the need to promote physical activity in type 1 diabetes care and lack of understanding on how to do this. This protocol paper describes a feasibility and pilot study of the ActivPals programme-an intervention to support active lifestyles in youths with type 1 diabetes. Key intervention components have been identified from preliminary work (individual and family focus, peer mentoring, technology integration and improved communication and understanding) and are being developed into a pragmatic randomised controlled trial (RCT) supported by recruitment pathways. A steering group of health care professionals and managers will refine the intervention to patient needs. A pilot trial is providing data on intervention implementation, acceptability and feasibility. Twenty youths with type 1 diabetes are being recruited and randomised into an intervention or control group. Physical activity is being measured objectively using the Actigraph GT3X+ monitor at baseline and 1-month follow-up. Contextual factors associated with intervention delivery are being explored. This study will contribute to the development of evidence-based, user-informed and pragmatic interventions leading to healthier lifestyles in youths with type 1 diabetes.

  19. Effects of Crocin on The Pituitary-Gonadal Axis and Hypothalamic Kiss-1 Gene Expression in Female Wistar Rats

    Directory of Open Access Journals (Sweden)

    Dina Zohrabi

    2018-01-01

    Full Text Available Background Saffron (Crocus sativus L. has been traditionally used as a spice for coloring and flavoring in some countries cuisine. One of the main components of saffron is Crocin. Recent research have shown that crocin has various pharmacological effects. The aim of this study was to assess the effects of crocin on the Pituitary-Gonadal axis and Kiss-1 gene expression in hypothalamus and ovarian tissue organization in female Wistar rats. Materials and Methods In this experimental study, 18 adult female Wistar rats were randomly divided into three groups. Control group received normal saline and experimental groups received two different doses of crocin (100 and 200 mg/kg every two days for 30 days. After the treatment period, blood samples were obtained from the heart and centrifuged. Next, the serum levels of follicle-stimulating hormone (FSH and luteinizing hormone (LH, estrogen and progesterone hormones were measured by ELISA assay. The ovarian tissues were removed and fixed for histological investigation. The hypothalamic Kiss-1 gene expression was measured using real-time polymerase chain reaction (PCR. All data were analyzed using one-way ANOVA. Results A significant reduction (P=0.038 in the number of atretic graafian follicles (0.5 ± 0.31 was observed in rats treated with 200 mg/kg crocin. In addition, estrogen concentration in experimental groups (35.04 ± 0.85 and 36.18 ± 0.69 in crocin 100 and 200 mg/kg groups, respectively compared to control group (38.35 ± 0.64 and progesterone concentration in rats treated with crocin 200 mg/kg (2.06 ± 0.07 compared to control group (2.16 ± 0.04, significantly decreased. Interestingly, relative expressions of Kiss-1 mRNA significantly decreased in experimental groups (0.00053 ± 0.00051 and 0.0011 ± 0.00066 in crocin 100 and 200 mg/kg groups, respectively (P=0.000 compared to control group (1 ± 0. Conclusion Crocin, at hypothalamic level, reduces Kiss-1 gene expression and it can prevent

  20. An O(n(5)) algorithm for MFE prediction of kissing hairpins and 4-chains in nucleic acids.

    Science.gov (United States)

    Chen, Ho-Lin; Condon, Anne; Jabbari, Hosna

    2009-06-01

    Efficient methods for prediction of minimum free energy (MFE) nucleic secondary structures are widely used, both to better understand structure and function of biological RNAs and to design novel nano-structures. Here, we present a new algorithm for MFE secondary structure prediction, which significantly expands the class of structures that can be handled in O(n(5)) time. Our algorithm can handle H-type pseudoknotted structures, kissing hairpins, and chains of four overlapping stems, as well as nested substructures of these types.

  1. Endovascular treatment for extrahepatic portal vein bifurcation stenosis after a Whipple procedure using the kissing stents technique.

    Science.gov (United States)

    Zhang, Wen-guang; Liu, Dong-mei; Li, Zhen; Wang, Yan-Li; Ding, Peng-xu; Zhou, Peng-li; Wang, Zhong-gao; Han, Xin-wei

    2014-01-01

    A 57-year-old man presented with a rare extrahepatic portal vein bifurcation scar stenosis involving the proximal splenic vein and superior mesenteric vein after a Whipple procedure. He was treated with endovascular coil embolization for the gastroesophageal varices and kissing stents for the portal vein bifurcation stenosis. This case illustrates a rarely seen complication after the Whipple procedure and a novel management strategy that can be considered in the management of this complex disease. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Differences in diagnostic activity in general practice and findings for individuals invited to the danish screening programme for colorectal cancer: a population-based cohort study.

    Science.gov (United States)

    Juul, Jakob Søgaard; Andersen, Berit; Laurberg, Søren; Carlsen, Anders Helles; Olesen, Frede; Vedsted, Peter

    2018-06-22

    To investigate the diagnostic activity in general practice and the cumulative incidence of colorectal cancer (CRC) in individuals invited to the Danish national screening programme for CRC. A historical population-based cohort study. The Danish CRC screening programme and general practice. The 376,198 individuals invited to the Danish CRC screening programme from 1 March to 31 December 2014. The diagnostic activity (consultations and haemoglobin measures) in general practice in the year preceding the screening invitation and the cumulated incidence of CRC in the year following the screening invitation. Screening participants had significantly higher diagnostic activity than non-participants. Individuals with a positive faecal immunochemical test (FIT) had higher diagnostic activity compared to individuals with a negative FIT, and a small increase in the months leading up to the invitation. Individuals with a screen-detected CRC had lower diagnostic activity than individuals with no CRC. In total, 308 (25.3%) of CRCs diagnosed in the invited population were diagnosed outside the screening programme. Non-participants with CRC more often had low socio-economic status, high comorbidity and stage IV CRC than participants with CRC. There was a tendency that participants and those with a positive FIT had a higher diagnostic activity the year before the screening. This was not seen for those with CRC detected through screening. CRC must still be diagnosed in general practice in the invited population and non-participants are of special interest as they have higher risk of late stage CRC. Key Points Current awareness:Individuals with colorectal cancer (CRC) in screening may be symptomatic and CRC may still occur outside screening in the invited population. Most important points:The majority of individuals with CRC in screening cannot be expected to be diagnosed on symptomatic presentation in general practice GPs have to be aware that CRC still occurs outside screening in

  3. The kissing-loop motif is a preferred site of 5' leader recombination during replication of SL3-3 murine leukemia viruses in mice

    DEFF Research Database (Denmark)

    Lund, Anders Henrik; Mikkelsen, J G; Schmidt, J

    1999-01-01

    , and the upstream part of the 5' untranslated region, enabled us to map recombination sites, guided by distinct scattered nucleotide differences. In 30 of 44 analyzed sequences, recombination was mapped to a 33-nucleotide similarity window coinciding with the kissing-loop stem-loop motif implicated in dimerization...... of the diploid genome. Interestingly, the recombination pattern preference found in replication-competent viruses from T-cell tumors is very similar to the pattern previously reported for retroviral vectors in cell culture experiments. The data therefore sustain the hypothesis that the kissing loop, presumably...

  4. Using intervention mapping to develop a culturally appropriate intervention to prevent childhood obesity: the HAPPY (Healthy and Active Parenting Programme for Early Years) study.

    Science.gov (United States)

    Taylor, Natalie J; Sahota, Pinki; Sargent, Judith; Barber, Sally; Loach, Jackie; Louch, Gemma; Wright, John

    2013-12-28

    Interventions that make extensive use of theory tend to have larger effects on behaviour. The Intervention Mapping (IM) framework incorporates theory into intervention design, implementation and evaluation, and was applied to the development of a community-based childhood obesity prevention intervention for a multi-ethnic population. IM was applied as follows: 1) Needs assessment of the community and culture; consideration of evidence-base, policy and practice; 2) Identification of desired outcomes and change objectives following identification of barriers to behaviour change mapped alongside psychological determinants (e.g. knowledge, self-efficacy, intention); 3) Selection of theory-based methods and practical applications to address barriers to behaviour change (e.g., strategies for responsive feeding); 4) Design of the intervention by developing evidence-based interactive activities and resources (e.g., visual aids to show babies stomach size). The activities were integrated into an existing parenting programme; 5) Adoption and implementation: parenting practitioners were trained by healthcare professionals to deliver the programme within Children Centres. HAPPY (Healthy and Active Parenting Programme for Early Years) is aimed at overweight and obese pregnant women (BMI > 25); consists of 12 × 2.5 hr. sessions (6 ante-natal from 24 weeks; 6 postnatal up to 9 months); it addresses mother's diet and physical activity, breast or bottle feeding, infant diet and parental feeding practices, and infant physical activity. We have demonstrated that IM is a feasible and helpful method for providing an evidence based and theoretical structure to a complex health behaviour change intervention. The next stage will be to assess the impact of the intervention on behaviour change and clinical factors associated with childhood obesity. The HAPPY programme is currently being tested as part of a randomised controlled feasibility trial.

  5. Nevo palpebral dividido - "kissing nevus": relato clínico-patológico e tratamento cirúrgico de três casos Divided nevus of the eyelid - kissing nevus: clinicopathological report and surgical treatment of three cases

    Directory of Open Access Journals (Sweden)

    Eduardo Ferrari Marback

    2002-03-01

    Full Text Available Objetivo: Relatar aspectos clínico-patológicos e tratamento cirúrgico em três casos de nevo palpebral dividido -"kissing nevus". Métodos: Revisão dos prontuários de três pacientes portadores de nevo palpebral dividido. Análise dos aspectos clínico-patológicos, das técnicas cirúrgicas e resultados do tratamento. Resultados: A cura das lesões com bom resultado estético e funcional foi conseguida em todos os casos. Conclusões: A exérese do nevo palpebral dividido, em mais de um tempo cirúrgico utilizando deslizamento de retalhos cutâneos palpebrais e, em um caso, transplante de pele da pálpebra superior contralateral foi curativa nos três casos estudados.Purpose: To describe the clinical and pathological aspects, surgical treatment and results of three cases of divided nevus -"kissing nevus"- of the eyelid. Methods: Review of the clinicopathological data and surgical techniques used to treat these patients. Results: Cure of the lesions with good esthetic and functional results were obtained in all cases. Conclusions: Surgical excision of the divided nevus of the eyelid in more than one surgical session using flaps from the adjacent skin, and in one case, a free skin graft from the contralateral superior lid, was curative in the studied three cases.

  6. Co-ordinated research and environmental surveillance programme related to sea disposal of radioactive waste CRESP activity report 1986-1990

    International Nuclear Information System (INIS)

    1990-01-01

    The Co-ordinated Research and Environmental Surveillance Programme relevant to sea disposal of radioactive waste (CRESP) was created in 1981 in the framework of the 1977 Decision of the OECD Council establishing a Multilateral Consultation and Surveillance Mechanism for Sea Dumping of Radioactive Waste. The main task of CRESP was to set up a site-specific scientific research programme to increase current knowledge of the processes controlling the transfer of radionuclides in the marine environment, so that impact of past dumping could be monitored and future assessments could be based on more accurate and comprehensive scientific data. The CRESP mandate was extended in 1987 to respond to a request from the Paris Commission to include consideration of radioactive discharges in the maritime area covered by the Convention on the Prevention of Marine Pollution from Land-Based Sources. This report summarizes the CRESP activities carried out during the 1986-1990 five year phase. Concerning the review of deep sea results, the report relates progress achieved above the level of knowledge which was available when the present phase of the CRESP programme was decided and which has been taken into account in the 1985 Site Suitability Review. With respect to coastal discharges, it presents a summary of R and D work undertaken by member countries, including those carried out in other programmes such as MARINA. Finally, it makes proposals for future work within CRESP

  7. Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.

    Science.gov (United States)

    Seabra, André; Katzmarzyk, Peter; Carvalho, Maria José; Seabra, Ana; Coelho-E-Silva, Manuel; Abreu, Sandra; Vale, Susana; Póvoas, Susana; Nascimento, Henrique; Belo, Luís; Torres, Sandra; Oliveira, José; Mota, Jorge; Santos-Silva, Alice; Rêgo, Carla; Malina, Robert M

    2016-10-01

    Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences.

  8. Policies to Accelerate Fuel, Technology andBehavioural Change in Transport - Results and Success of the Austrian Climate: Active Mobile Programme after the First Seven Years

    International Nuclear Information System (INIS)

    Jelinek, R.

    2012-01-01

    There is plenty of concepts and strategies on almost all administrative levels to reduce carbon emissions and boost energy efficiency in transport. But it usually takes a long time to adapt national and regional legislation to these strategies with considerable loss of valuable time. Furthermore some of the defined measures will never find the necessary ''political will'' for implementation. To bridge this gap Austria's Environmental ministry supported by the Austrian Energy Agency, got into action 2005 and set up an action programme, condensing all so called ''soft'' and ''voluntary'' measures in transport (''mobility management''), that do not necessarily need to wait for legislation or specific administrative framework conditions. In its comprehensive approach - not only transport is targeted, but also buildings, renewables and energy saving - and also in its effects regarding the reduction of GHG emissions, Climate:active and especially climate:active mobile seems to be one-of-a-kind in Europe. Climate-active mobile set-up: free-of-charge consulting programmes addressing specific target groups (companies, cites andmunicipalities, real estate developers, schools andyouth, tourism); a financial support programme with 51 Mio Euro since 2007 for mobility management measures, fleet conversions to low-carbon technologies, work travel plans etc.; an EcoDriving training programme with up to now 20,000 trainees and educating all novice drivers in Austria in a smart driving style; a broad awareness raising campaign; about 2,900 klima:aktiv mobil partners among the target groups implementing sustainable transport measures and therewith reduces more than 530,000 tons of CO 2 emissions every year, created or saved 4300 ''green jobs'' in transport and induced ''green'' investments by companies and administrations 7 to 8 times higher as the funding. Climate-active mobile is one of the main drivers in Austria to accelerate fuel, technology andbehavioural change in transport

  9. Effective promotion of healthy nutrition and physical activity in Europe requires skilled and competent people; European Master's Programme in Public Health Nutrition.

    Science.gov (United States)

    Yngve, A; Sjöström, M; Warm, D; Margetts, B; Rodrigo, C P; Nissinen, A

    1999-09-01

    Scientists in basic research and epidemiology deliver messages to policy makers. Effective population based strategies then require people trained and competent in the discipline of Public Health Nutrition (PHN). Since 1997, a European Master's Programme in PHN has been undergoing planning and implementation with the aid of funding from the European Commission (DGV). PHN is used as a broad term covering Nutrition and Physical Activity as well as Health Promotion and Disease Prevention. The partners in this project are academic departments from 17 countries. The students will undertake core modules and electives for a year and a half, followed by a research project for six months. In order to set up formalised procedures for the evaluation of the quality assurance of individual modules from across Europe, a quality assurance system has been set up. The academic year 1999-2000 will allow an opportunity for Universities and Institutes to start new modules, to develop other modules, assess the movement of students between modules, tackle funding issues and allow further marketing of the programme. Future activities include strengthening of the European Network for Public Health Nutrition (ENPHN), the establishment of a consortium with universities, the co-ordination of programme activities with other European Master's Programmes in Public Health, and the incorporation of new Member States from Eastern Europe. We can look forward to a new brand of professionals, who are truly European in their training, but who also have an integrated view of nutrition and physical activity, health promotion and disease prevention and who are prepared for policy making, action planning, implementation and evaluation.

  10. Feasibility and acceptability of a midwife-led intervention programme called 'Eat Well Keep Active' to encourage a healthy lifestyle in pregnancy

    Directory of Open Access Journals (Sweden)

    Warren Lucie

    2012-04-01

    Full Text Available Abstract Background Eating a diet that is high in fat and sugar and having a sedentary lifestyle during pregnancy is understood to increase the risk of excessive gestational weight gain and obesity following the birth of the baby. However, there are no clinical guidelines in the UK on what is considered to be appropriate gestational weight gain. Indeed, clinical recommendations discourage the routine re-weighing of pregnant women, stating instead that women should be advised regarding their diet and activity levels, in order to prevent excessive weight gain. Pregnancy is seen as a time when many women may have an increased motivation to improve their lifestyle behaviours for the benefit of the fetus. However, it is evident that many women have difficulty in both maintaining a healthy balanced diet and remaining active through pregnancy. It would seem that midwives may be ideally placed to assist women to make and maintain healthier lifestyle choices during pregnancy. Methods/design This study will look at the feasibility and acceptability of a newly devised intervention programme called 'Eat Well Keep Active'. Participants will complete a questionnaire prior to the programme to obtain baseline data on food frequency, physical activity and to gauge their perception of personal ability to improve/maintain healthy lifestyle. The programme comprises client centred techniques; motivational interviewing and goal setting delivered early in pregnancy (12-16 weeks with the aim of supporting a healthy well balanced diet and either continuing or commencing appropriate levels of physical activity. Participants will then be followed up six weeks following the intervention with a one-to-one interview, and a further brief questionnaire. The interview will provide preliminary data regarding perceived effectiveness and acceptability of the 'Eat Well Keep Active' programme whilst the questionnaire will provide data regarding changes in the confidence of

  11. Feasibility and acceptability of a midwife-led intervention programme called 'Eat Well Keep Active' to encourage a healthy lifestyle in pregnancy.

    Science.gov (United States)

    Warren, Lucie; Rance, Jaynie; Hunter, Billie

    2012-04-11

    Eating a diet that is high in fat and sugar and having a sedentary lifestyle during pregnancy is understood to increase the risk of excessive gestational weight gain and obesity following the birth of the baby. However, there are no clinical guidelines in the UK on what is considered to be appropriate gestational weight gain. Indeed, clinical recommendations discourage the routine re-weighing of pregnant women, stating instead that women should be advised regarding their diet and activity levels, in order to prevent excessive weight gain. Pregnancy is seen as a time when many women may have an increased motivation to improve their lifestyle behaviours for the benefit of the fetus. However, it is evident that many women have difficulty in both maintaining a healthy balanced diet and remaining active through pregnancy. It would seem that midwives may be ideally placed to assist women to make and maintain healthier lifestyle choices during pregnancy. This study will look at the feasibility and acceptability of a newly devised intervention programme called 'Eat Well Keep Active'. Participants will complete a questionnaire prior to the programme to obtain baseline data on food frequency, physical activity and to gauge their perception of personal ability to improve/maintain healthy lifestyle. The programme comprises client centred techniques; motivational interviewing and goal setting delivered early in pregnancy (12-16 weeks) with the aim of supporting a healthy well balanced diet and either continuing or commencing appropriate levels of physical activity. Participants will then be followed up six weeks following the intervention with a one-to-one interview, and a further brief questionnaire. The interview will provide preliminary data regarding perceived effectiveness and acceptability of the 'Eat Well Keep Active' programme whilst the questionnaire will provide data regarding changes in the confidence of participants to lead a healthy lifestyle. There is an

  12. Monitoring programme

    International Nuclear Information System (INIS)

    1994-06-01

    Her Majesty's Inspectorate of Pollution's 1992 report on its programme of monitoring radioactive substances is presented. Site operators' returns are verified and the report provides independent data on the environmental impact of authorized disposal of radioactive wastes. Radiation doses which may have been received by members of the public, fall well below the International Commission for Radiological Protection's (ICRP) recommended annual doses. (UK)

  13. Two-reactor solution spells kiss of death for the SGHWR option

    International Nuclear Information System (INIS)

    Butler, P.

    1977-01-01

    The main points from the National Nuclear Corporation's assessment of thermal reactors are summarised. Three systems SGHWR, AGR, and PWR were examined. The NNC suggests extending the AGR programme whilst at the same time developing a PWR. (U.K.)

  14. The ProActive trial protocol – a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766

    Directory of Open Access Journals (Sweden)

    Ekelund Ulf

    2004-10-01

    Full Text Available Abstract Background Increasing prevalence of obesity and disorders associated with sedentary living constitute a major global public health problem. While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease. Methods/design ProActive aims to evaluate the efficacy of a theoretical, evidence- and family-based intervention programme to increase physical activity in a sedentary population, defined as being at-risk through having a parental family history of diabetes. Primary care diabetes or family history registers were used to recruit 365 individuals aged 30–50 years, screened for activity level. Participants were assigned by central randomisation to three intervention programmes: brief written advice (comparison group, or a psychologically based behavioural change programme, delivered either by telephone (distance group or face-to-face in the family home over one year. The protocol-driven intervention programme is delivered by trained facilitators, and aims to support increases in physical activity through the introduction and facilitation of a range of self-regulatory skills (e.g. goal setting. The primary outcome is daytime energy expenditure and its ratio to resting energy expenditure, measured at baseline and one year using individually calibrated heart rate monitoring. Secondary measures include self-report of individual and family activity, psychological mediators of behaviour change, physiological and biochemical correlates, acceptability, and costs, measured at baseline, six months and one year. The primary intention to treat analysis will compare groups at one-year post randomisation. Estimation of the impact on diabetes incidence will be modelled using data from a parallel ten-year cohort study using similar measures. Discussion ProActive is the first efficacy trial of an

  15. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system.

    Science.gov (United States)

    Maher, Dermot

    2010-07-05

    The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens), drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens), research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy development and scaling up interventions, and identify ways

  16. Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system

    Directory of Open Access Journals (Sweden)

    Maher Dermot

    2010-07-01

    Full Text Available Abstract Background The global financial crisis threatens global health, particularly exacerbating diseases of inequality, e.g. HIV/AIDS, and diseases of poverty, e.g. tuberculosis. The aim of this paper is to reconsider established practices and policies for HIV and tuberculosis epidemic control, aiming at delivering better results and value for money. This may be achieved by promoting greater integration of HIV and tuberculosis control programme activities within a strengthened health system. Discussion HIV and tuberculosis share many similarities in terms of their disease burden and the recommended stratagems for their control. HIV and tuberculosis programmes implement similar sorts of control activities, e.g. case finding and treatment, which depend for success on generic health system issues, including vital registration, drug procurement and supply, laboratory network, human resources, and financing. However, the current health system approach to HIV and tuberculosis control often involves separate specialised services. Despite some recent progress, collaboration between the programmes remains inadequate, progress in obtaining synergies has been slow, and results remain far below those needed to achieve universal access to key interventions. A fundamental re-think of the current strategic approach involves promoting integrated delivery of HIV and tuberculosis programme activities as part of strengthened general health services: epidemiological surveillance, programme monitoring and evaluation, community awareness of health-seeking behavior, risk behaviour modification, infection control, treatment scale-up (first-line treatment regimens, drug-resistance surveillance, containing and countering drug-resistance (second-line treatment regimens, research and development, global advocacy and global partnership. Health agencies should review policies and progress in HIV and tuberculosis epidemic control, learn mutual lessons for policy

  17. Development and implementation of a lifestyle intervention to promote physical activity and healthy diet in the Dutch general practice setting: the BeweegKuur programme

    Directory of Open Access Journals (Sweden)

    de Vries Nanne K

    2010-05-01

    Full Text Available Abstract Background The number of patients with diabetes is increasing. BeweegKuur (Dutch for 'Exercise Therapy' is a Dutch lifestyle intervention which aims to effectively and feasibly promote physical activity and better dietary behaviour in primary health care to prevent diabetes. Methods The goal of this paper is to present the development process and the contents of the intervention, using a model of systematic health promotion planning. The intervention consists of a 1-year programme for diabetic and prediabetic patients. Patients are referred by their general practitioner (GP to a lifestyle advisor (LSA, usually the practice nurse or a physiotherapist. Based on specific inclusion criteria and in close collaboration with the patient, an individual exercise programme is designed and supervised by the LSA. This programme can be attended at existing local exercise facilities or (temporarily under the supervision of a specialized exercise coach or physiotherapist. All participants are also referred to a dietician and receive diet-related group education. In the first pilot year (2008, the BeweegKuur programme was implemented in 7 regions in the Netherlands (19 GP practices and health centres, while 14 regions (41 GP practices and health centres participated during the second year. The aim is to implement BeweegKuur in all regions of the Netherlands by 2012. Discussion The BeweegKuur programme was systematically developed in an evidence- and practice-based process. Formative monitoring studies and (controlled effectiveness studies are needed to examine the diffusion process and the effectiveness and cost-effectiveness of the intervention.

  18. The need for theory evaluation in global citizenship programmes: The case of the GCSA programme.

    Science.gov (United States)

    Goodier, Sarah; Field, Carren; Goodman, Suki

    2018-02-01

    Many education programmes lack a documented programme theory. This is a problem for programme planners and evaluators as the ability to measure programme success is grounded in the plausibility of the programme's underlying causal logic. Where the programme theory has not been documented, conducting a theory evaluation offers a foundational evaluation step as it gives an indication of whether the theory behind a programme is sound. This paper presents a case of a theory evaluation of a Global Citizenship programme at a top-ranking university in South Africa, subsequently called the GCSA Programme. This evaluation highlights the need for documented programme theory in global citizenship-type programmes for future programme development. An articulated programme theory produced for the GCSA Programme, analysed against the available social science literature, indicated it is comparable to other such programmes in terms of its overarching framework. What the research found is that most other global citizenship programmes do not have an articulated programme theory. These programmes also do not explicitly link their specific activities to their intended outcomes, making demonstrating impact impossible. In conclusion, we argue that taking a theory-based approach can strengthen and enable outcome evaluations in global citizenship programmes. Copyright © 2017. Published by Elsevier Ltd.

  19. Effects of a multicomponent workplace intervention programme with environmental changes on physical activity among Japanese white collar employees: a protocol for a cluster randomised controlled trial.

    Science.gov (United States)

    Watanabe, Kazuhiro; Kawakami, Norito

    2017-10-24

    Physical activity is one of the most important health behaviours as a determinant of physical and mental health. Although intervention strategies for promoting physical activity among workers are needed, evidence for the effectiveness of multilevel workplace interventions with environmental changes on the promotion of physical activity are still limited due to lack of cluster randomised controlled trials (RCTs). The aim of this study is to investigate effects of a 3-month workplace intervention programme with environmental changes on the improvement in physical activity among Japanese white collar employees. This study will be a two-arm and parallel-group cluster (worksite) RCT. Japanese worksites and employees who are employed by the worksites will be recruited through health insurance associations and chambers of commerce. Worksites that meet the inclusion criteria will be randomly allocated to intervention or control groups. The intervention worksites will be offered the original intervention programme that consists of 13 contents with environmental changes. The control worksites will be able to get three times feedback of the assessment of the amount of physical activity and basic occupational health service in each worksite. The primary outcome will be the total amount of physical activity measured by the Global Physical Activity Questionnaire at baseline, 3 months and 6 months. Multilevel latent growth modelling will be conducted to examine the effectiveness of the intervention programme. This study was ethically approved by the research ethics committee of the Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Japan (No. 11230). Results will be submitted and published in a scientific peer-reviewed journal. UMIN000024069; Pre-results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  20. A social cognitive theory-based programme for eating patterns and sedentary activity among overweight adolescents in Makassar, South Sulawesi : a cluster randomised controlled trial.

    Science.gov (United States)

    Hidayanty, Healthy; Bardosono, Saptawati; Khusun, Helda; Damayanti, Rita; Kolopaking, Risatianti

    2016-12-01

    Social cognitive theory provides the opportunity for program development to enhance healthy personal behvioural characteristics. We devised study to employ social cognitive theory to reduce snacking habits and sedentary activity among overweight adolescents . Eight junior high schools in Makassar city were randomly assigned as intervention and control schools. A total of 238 overweight students aged 11-15 years (BMI z-score >=1 SD, according to a 2007 report from the WHO) were recruited. Adolescents from the intervention schools attended 12 weekly 75-min nutrition education group sessions, which focused on behavioural modification assisted by trained facilitators; furthermore, their parents received weekly nutrition education leaflets. Adolescents from the control schools, but not their parents, received leaflets on evidenced-based nutrition information. The BMI z-scores, waist circumference, snacking habits, sedentary activity, and the adolescents' self-efficacy data were assessed prior to and after 3 months of intervention. The outcomes were analysed on an intent-to-treat basis. Compared with the control group, the intervention group showed a higher reduction in BMI z-scores (-0.08; p<0.05) and waist circumference (-1.5; p<0.05) at 3 months. Significant between-group differences were also observed for decreased snacking habits, but not for sedentary activity. Additionally, the programme improved self-efficacy for reducing these behaviours. Mean compliance and satisfaction with the programme were 95% and 92%, respectively. These high reduction rates suggest that the programme is promising and may address the problem of overweightness in adolescents. Additional studies are required to develop the programme in community settings.

  1. Referral from primary care to a physical activity programme: establishing long-term adherence? A randomized controlled trial. Rationale and study design

    Directory of Open Access Journals (Sweden)

    Puig-Ribera Anna

    2009-01-01

    Full Text Available Abstract Background Declining physical activity is associated with a rising burden of global disease. There is little evidence about effective ways to increase adherence to physical activity. Therefore, interventions are needed that produce sustained increases in adherence to physical activity and are cost-effective. The purpose is to assess the effectiveness of a primary care physical activity intervention in increasing adherence to physical activity in the general population seen in primary care. Method and design Randomized controlled trial with systematic random sampling. A total of 424 subjects of both sexes will participate; all will be over the age of 18 with a low level of physical activity (according to the International Physical Activity Questionnaire, IPAQ, self-employed and from 9 Primary Healthcare Centres (PHC. They will volunteer to participate in a physical activity programme during 3 months (24 sessions; 2 sessions a week, 60 minutes per session. Participants from each PHC will be randomly allocated to an intervention (IG and control group (CG. The following parameters will be assessed pre and post intervention in both groups: (1 health-related quality of life (SF-12, (2 physical activity stage of change (Prochaska's stages of change, (3 level of physical activity (IPAQ-short version, (4 change in perception of health (vignettes from the Cooperative World Organization of National Colleges, Academies, and Academic Associations of Family Physicians, COOP/WONCA, (5 level of social support for the physical activity practice (Social Support for Physical Activity Scale, SSPAS, and (6 control based on analysis (HDL, LDL and glycated haemoglobin. Participants' frequency of visits to the PHC will be registered over the six months before and after the programme. There will be a follow up in a face to face interview three, six and twelve months after the programme, with the reduced version of IPAQ, SF-12, SSPAS, and Prochaska's stages

  2. Systematic review on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity.

    Science.gov (United States)

    van Dongen, J M; Proper, K I; van Wier, M F; van der Beek, A J; Bongers, P M; van Mechelen, W; van Tulder, M W

    2011-12-01

    This systematic review summarizes the current evidence on the financial return of worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity. Data on study characteristics and results were extracted from 18 studies published up to 14 January 2011. Two reviewers independently assessed the risk of bias of included studies. Three metrics were (re-)calculated per study: the net benefits, benefit cost ratio (BCR) and return on investment (ROI). Metrics were averaged, and a post hoc subgroup analysis was performed to compare financial return estimates between study designs. Four randomized controlled trials (RCTs), 13 non-randomized studies (NRSs) and one modelling study were included. Average financial return estimates in terms of absenteeism benefits (NRS: ROI 325%, BCR 4.25; RCT: ROI -49%, BCR 0.51), medical benefits (NRS: ROI 95%, BCR 1.95; RCT: ROI -112%, BCR -0.12) or both (NRS: ROI 387%, BCR 4.87; RCT: ROI -92%, BCR 0.08) were positive in NRSs, but negative in RCTs. Worksite health promotion programmes aimed at improving nutrition and/or increasing physical activity generate financial savings in terms of reduced absenteeism costs, medical costs or both according to NRSs, whereas they do not according to RCTs. Since these programmes are associated with additional types of benefits, conclusions about their overall profitability cannot be made. © 2011 The Authors. obesity reviews © 2011 International Association for the Study of Obesity.

  3. Effects of a self-guided, web-based activity programme for patients with persistent musculoskeletal pain in primary healthcare: A randomized controlled trial.

    Science.gov (United States)

    Calner, T; Nordin, C; Eriksson, M K; Nyberg, L; Gard, G; Michaelson, P

    2017-07-01

    Web-based interventions for pain management are increasingly used with possible benefits, but never used in addition to multimodal rehabilitation (MMR). MMR is recommended treatment for persistent pain in Sweden. The aim was to evaluate the effects of a self-guided, web-based programme added to MMR for work ability, pain, disability and health-related quality of life. We included 99 participants with persistent musculoskeletal pain in a randomized study with two intervention arms: (1) MMR and web-based intervention, and (2) MMR. Data was collected at baseline, 4 and 12 months. Outcome measures were work ability, working percentage, average pain intensity, pain-related disability, and health-related quality of life. There were no significant effects of adding the web-based intervention to MMR regarding any of the outcome variables. This trial provides no support for adding a self-guided, web-based activity programme to MMR for patients with persistent musculoskeletal pain. The comprehensive self-guided, web-based programme for activity, Web-BCPA, added to multimodal treatment in primary health care had no effect on work ability, pain, disability or health-related quality of life. Future web-based interventions should be tailored to patients' individual needs and expectations. © 2017 European Pain Federation - EFIC®.

  4. The correlation between birth weight and insulin-like growth factor-binding protein-1 (IGFBP-1), kisspeptin-1 (KISS-1), and three-dimensional fetal volume.

    Science.gov (United States)

    Kimyon Comert, Gunsu; Esin, Sertac; Caglar, Gamze Sinem; Yirci, Bulent; Ozdemir, Sedat; Demirtas, Selda; Kandemir, Omer

    2018-01-24

    This study aimed to determine the relationship between birth weight, and maternal serum insulin-like growth factor-binding protein-1 (IGFBP-1) and kisspeptin-1 (KISS-1) levels, and first-trimester fetal volume (FV) based on three-dimensional ultrasonography. The study included 142 pregnant women at gestational week 11°-13 6 . All fetuses were imaged ultrasonographically by the same physician. Maternal blood samples were collected at the time of ultrasonographic evaluation and analyzed for IGFBP-1 and KISS-1 levels via enzyme-linked immunosorbent assay (ELISA). Maternal and neonatal weights were recorded at birth. Birth weight ≤10th and the >90th percentiles was defined as small and large for gestational age (SGA and LGA), respectively. Median crown-rump length (CRL), FV, and maternal serum IGFBP-1 and KISS-1 levels were 58.2 mm (35.3-79.2 mm), 16.3 cm 3 (3.8-34.4 cm 3 ), 68.1 ng mL -1 (3.8-377.9 mL -1 ), and 99.7 ng L -1 (42.1-965.3 ng L -1 ), respectively. First-trimester IGFBP-1 levels were significantly lower in the mothers with LGA neonates (p KISS-1 levels. IGFBP-1 levels and maternal weight at delivery were negatively correlated with neonatal birth weight. There was no correlation between CRL or FV and maternal IGFBP-1 or KISS1 levels (p > .05). The maternal IGFBP-1 level during the first trimester was a significant independent factor for SGA and LGA neonates (Odds ratio (OR): 0.011, 95%CI: 1.005-1.018, p KISS-1 level. As compared to the maternal KISS-1 level, the maternal IGFBP-1 level during the first trimester might be a better biomarker of fetal growth. Additional larger scale studies are needed to further delineate the utility of IGFBP-1 as a marker of abnormal birth weight.

  5. SET-Routes programme

    CERN Multimedia

    Marietta Schupp, EMBL Photolab

    2008-01-01

    Dr Sabine Hentze, specialist in human genetics, giving an Insight Lecture entitled "Human Genetics – Diagnostics, Indications and Ethical Issues" on 23 September 2008 at EMBL Heidelberg. Activities in a achool in Budapest during a visit of Angela Bekesi, Ambassadors for the SET-Routes programme.

  6. Conceptualizing Programme Evaluation

    Science.gov (United States)

    Hassan, Salochana

    2013-01-01

    The main thrust of this paper deals with the conceptualization of theory-driven evaluation pertaining to a tutor training programme. Conceptualization of evaluation, in this case, is an integration between a conceptualization model as well as a theoretical framework in the form of activity theory. Existing examples of frameworks of programme…

  7. The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in polio survivors: protocol for a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Murray Deirdre

    2012-12-01

    Full Text Available Abstract Background Many Polio survivors have reduced mobility, pain and fatigue, which make access to conventional forms of aerobic exercise difficult. Inactivity leads to increased risk of health problems, many of which are prevalent among Polio survivors. Aerobic exercise programmes in Polio survivors should utilise stable muscle groups and should be designed to minimise exacerbation of pain and fatigue. A home-based arm ergometry aerobic exercise programme may represent an affordable and accessible exercise modality, incorporating exercise prescription principles in this group. Methods/design This is a prospective, single blinded, randomised controlled trial. There are two arms; exercise intervention using arm ergometers and control. Polio survivors meeting eligibility criteria will be recruited and randomly allocated to intervention or control groups. Participants allocated to the intervention group will receive a small arm ergometer and a polar heart rate monitor. They will carry out a home-based moderate intensity (50-70% HRMax aerobic exercise programme for eight weeks, following instruction by the treating physiotherapist. Assessments will occur at baseline and after eight weeks and will include tests of physical fitness, activity, energy cost of walking, fatigue and quality of life. Clinically feasible assessment tools including the Six Minute Arm Test, the Physical Activity Scale for People with Physical Disabilities questionnaire, the Physiological Cost Index, Fatigue Severity Scale and the SF-36v2 will be utilised. Discussion The efficacy of a home-based arm ergometry programme in Polio survivors will be examined. No previous trial has examined such a programme using a wide range of outcome measures pertinent to Polio survivors. This study will provide new information on the impact of arm ergometry on physical fitness, activity, body composition, fatigue, pain, muscle strength, and health related quality of life. Also, the study

  8. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III

    DEFF Research Database (Denmark)

    Niemelä, Matti; Kervinen, Kari; Erglis, Andrejs

    2011-01-01

    BACKGROUND: It is unknown whether the preferred 1-stent bifurcation stenting approach with stenting of the main vessel (MV) and optional side branch stenting using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies of MV stenting......, or stent thrombosis within 6 months. The 6-month major adverse cardiac event rates were 2.1% and 2.5% (P=1.00) in the FKBD and no-FKBD groups, respectively. Procedure and fluoroscopy times were longer and more contrast media was needed in the FKBD group than in the no-FKBD group. Three hundred twenty...... angiographic side branch (re)stenosis, especially in patients with true bifurcation lesions. The simple no-FKBD procedures resulted in reduced use of contrast media and shorter procedure and fluoroscopy times. Long-term data on stent thrombosis are needed....

  9. Randomized Comparison of Final Kissing Balloon Dilatation Versus No Final Kissing Balloon Dilatation in Patients With Coronary Bifurcation Lesions Treated With Main Vessel Stenting. Five Year Clinical Outcome in The Nordic-Baltic Bifurcation Study III

    DEFF Research Database (Denmark)

    Niemelä, Matti; Holm, Niels R; Kervinen, Kari

    2015-01-01

    Background- It is unknown whether the preferred 1-stent bifurcation stenting approach with stenting of the main vessel (MV) and optional side branch stenting using drug-eluting stents should be finalized by a kissing balloon dilatation (FKBD). Therefore, we compared strategies of MV stenting......, or stent thrombosis within 6 months. The 6-month major adverse cardiac event rates were 2.1% and 2.5% (P=1.00) in the FKBD and no-FKBD groups, respectively. Procedure and fluoroscopy times were longer and more contrast media was needed in the FKBD group than in the no-FKBD group. Three hundred twenty...... angiographic side branch (re)stenosis, especially in patients with true bifurcation lesions. The simple no-FKBD procedures resulted in reduced use of contrast media and shorter procedure and fluoroscopy times. Long-term data on stent thrombosis are needed. Clinical Trial Registration- URL: http...

  10. IAEA co-ordinated research programme on the transport of low specific activity materials and surface contaminated objects

    International Nuclear Information System (INIS)

    Gray, I.L.S.

    2000-01-01

    The International Atomic Energy Agency (IAEA) prepares regulations for the safe transport of radioactive material, and periodically revised editions of these are published. These regulations are adopted by individual countries across the world and by international organisations concerned with transport. Whilst it is desirable to have a stable framework of regulatory requirements, there is also a need to take account of technical advances and operational experience and revise the regulations. From time to time Co-ordinated Research Programmes (CRP) are established to investigate particular areas of the regulations that are giving concern. In 1996 the IAEA Standing Advisory Group on the Transport of Radioactive Material (SAGSTRAM) concluded that the requirements for classification, packaging and transport of low specific activity (LSA) material and surface contaminated objects (SCO) did not always have a strong radiation protection basis. Accordingly SAGSTRAM established a CRP with an overall objective to develop a dose-based approach for establishing LSA/SCO requirements. Six countries are participating in this CRP. Brazil, Canada, France, Germany, United Kingdom and United States. Each country is carrying out work that is outlined in agreements with the IAEA, with the work aimed at meeting the specific objective of the agreement and also contributing to achieving the overall objective of the CRP. Completion of the CRP usually involves the preparation of an IAEA TECDOC by a Consultant Services Meeting (CSM), and this TECDOC will summarise the work performed under the CRP and include any recommendations made by the CRP. Following the establishment of the CRP in 1997, the first Research Co-ordination Meeting (RCM) was held in December 1997. The second RCM was held in March 1999, with the final RCM planned for the end of 2000. The work being carried out by Brazil and Canada is focused upon the transport of uranium and thorium ores, and is a mixture of theoretical and

  11. Physical activity levels in locally advanced rectal cancer patients following neoadjuvant chemoradiotherapy and an exercise training programme before surgery: a pilot study.

    Science.gov (United States)

    Loughney, Lisa; West, Malcolm A; Dimitrov, Borislav D; Kemp, Graham J; Grocott, Michael Pw; Jack, Sandy

    2017-01-01

    The aim of this pilot study was to measure changes in physical activity level (PAL) variables, as well as sleep duration and efficiency in people with locally advanced rectal cancer (1) before and after neoadjuvant chemoradiotherapy (CRT) and (2) after participating in a pre-operative 6-week in-hospital exercise training programme, following neoadjuvant CRT prior to major surgery, compared to a usual care control group. We prospectively studied 39 consecutive participants (27 males). All participants completed standardised neoadjuvant CRT: 23 undertook a 6-week in-hospital exercise training programme following neoadjuvant CRT. These were compared to 16 contemporaneous non-randomised participants (usual care control group). All participants underwent a continuous 72-h period of PA monitoring by SenseWear biaxial accelerometer at baseline, immediately following neoadjuvant CRT (week 0), and at week 6 (following the exercise training programme). Of 39 recruited participants, 23 out of 23 (exercise) and 10 out of 16 (usual care control) completed the study. In all participants ( n  = 33), there was a significant reduction from baseline (pre-CRT) to week 0 (post-CRT) in daily step count: median (IQR) 4966 (4435) vs. 3044 (3265); p  exercise group compared to the usual care control group (80 (13) vs. 78 (15) compared to (69 ((24) vs. 76 (20); p  = 0.022), as well as in sleep duration and lying down time ( p  importance but did not reach statistical significance ( p  > 0.05). An apparent improvement in daily step count and overall PAL in the exercise group was not statistically significant. PAL variables, daily step count, EE and MET significantly reduced following neoadjuvant CRT in all participants. A 6-week pre-operative in-hospital exercise training programme improved sleep efficiency, sleep duration and lying down time when compared to participants receiving usual care. Clinicaltrials.gov NCT01325909.

  12. Assessing participants' perceptions on group-based principles for action in community-based health enhancing physical activity programmes: The APEF tool.

    Science.gov (United States)

    Herens, Marion; Wagemakers, Annemarie

    2017-12-01

    In community-based health enhancing physical activity (CBHEPA) programmes, group-based principles for action such as active participation, enjoyment, and fostering group processes are widely advocated. However, not much is known about participants' perceptions of these principles as there are no assessment tools available. Therefore, this article describes the development of the APEF (Active Participation, Enjoyment, and Fostering group processes) tool and reports on its implementation in a Dutch CBHEPA programme. Indicators for the principles have been identified from literature research, interviews with professionals, and secondary analysis of three group interviews with 11 practitioners. To address the identified indicators, the APEF tool was developed, pretested, and used in 10 focus groups with 76 participants. The APEF tool consists of eight statements about group-based principles for action, on which CBHEPA participants vote, followed by in-depth discussion. The voting procedure engages participants. Spider diagrams visualise participants' perceptions of group-based principles. The APEF tool addresses the challenge of relating group level outcomes to individual outcomes such as physical activity behaviour. The tool facilitates as well as evaluates group-based principles for action, it stimulates dialogue and is culturally sensitive, but it needs strong facilitating skills to manage group dynamics. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. The Possibility of Social Change and Pop Music in Serbia: Šobaja’s Three Kisses – A Case Study

    Directory of Open Access Journals (Sweden)

    Aleksandar Brkić

    2016-02-01

    Full Text Available Can social change be brought about only in a radical manner? Is a radical manner of bringing about change possible at all? When we say social change, do we mean "revolution"? Is there a different way of looking at social change, and what is the role of elite culture and that of popular culture in these processes? Has the temporally and contextually limited effect of change and guerilla subversion through popular culture proved more effective? This small-scale study aims to raise the question of whether pop music can contribute to positive changes in society, and examines the conditions for this possibility through the case study of Nebojša "Šobaja" Anđelković’s song Three Kisses, declared the biggest music hit of 2009 in Serbia.

  14. The rice F-box protein KISS ME DEADLY2 functions as a negative regulator of cytokinin signalling.

    Science.gov (United States)

    Kim, Hyo Jung; Kieber, Joseph J; Schaller, G Eric

    2013-01-01

    Cytokinins are plant hormones that play critical roles in growth and development. We recently determined that the transcriptional response to cytokinin of Arabidopsis is modulated by the KISS ME DEADLY (KMD) family of F-box proteins. Here we demonstrate a conserved function for a member of the rice KMD family. Ectopic overexpression of OsKMD2 in Arabidopsis results in decreased cytokinin sensitivity based on a hypocotyl growth response assay, the decrease in sensitivity correlating with a decrease in the levels of the transcriptional regulator AtARR12. Furthermore, OsKMD2 directly interacts with AtARR12 based on yeast two-hybrid and co-immunoprecipitation assays. These results indicate that both monocots and dicots employ a similar KMD-dependent mechanism to regulate the transcriptional response to cytokinin.

  15. Personal goals, group performance and ‘social’ networks: participants’ negotiation of virtual and embodied relationships in the ‘Workplace Challenge’ physical activity programme

    DEFF Research Database (Denmark)

    Evans, Adam Brian; Carter, Alice; Middleton, Geoff

    2016-01-01

    -structured interviews were conducted with a total of seventeen participants recruited from one public and one private sector workplace and from a sample of participants registered as individuals. Two programme planners employed by the CSP also took part. A figurational framework was utilised to investigate participants...... in professional I–We identities, whereas virtual networks sometimes highlighted participants’ isolation. Moreover, emphasis upon competition within and between teams caused some participants to question their performance. Often, competition motivated engagement. For less active participants, constant comparison...

  16. What is the IAEA? Programmes and activities that maximize the contribution of nuclear technology to society, while verifying its peaceful use

    International Nuclear Information System (INIS)

    2001-01-01

    The International Atomic Energy Agency (IAEA) serves as the world's foremost international governmental forum for scientific and technical co-operation in the peaceful use of nuclear technology. Established as an autonomous organization under the United Nations (UN) in 1957, the IAEA represents the culmination of international efforts to make a reality of US President Eisenhower's proposal in his 'Atoms for Peace' speech to the UN General Assembly in 1953. He envisioned the creation of an international body to control and develop the use of atomic energy. Today, the Agency's broad spectrum of services, programmes, and activities is based on the needs of its 130 Member States

  17. Programme wood/energy 2000-2006. Activity Report for 2000-2004; Programme national Bois-Energie 2000-2006. Rapport d'activites 2000-2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    When ADEME launched its Wood fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report makes a status of ADEME's Wood fuel programme for the 2000-2004 era: - Domestic heating: After a drop during the 1990's, figures since 1999 of sales of wood-fuel domestic heating equipment (closed heaters, glass-door fires and stoves) have shown a significant rise. On average over 30 years, wood consumption has risen to 7.2 million TOE (40 million cubic metres) per year; - Industry: It is thought there are 1000 wood-fired heaters (above 1 megawatt) used in French industry. These are found mainly in timber-based industries and in timber crushing plants. This amounts to a total power output of 2.5 gigawatts. In the primary and secondary wood processing industries, the increase in the number of wood-fired boilers and energy produced has reached 5% per year Results of a call for carbon energy projects (APEC) was 61 submitted of which 52 were selected; 9 projects pending (166.5 K of aid from ADEME); and 35 projects begun (1,649 K of aid from ADEME). - Local authority and service sector wood-fired heating systems: At the end of 2004, the number of local authority active boilers was 641, producing 430 megawatts. This is an increase of an average of 13% year on year since 2000. By the end of 2004, the target had already been met for the number of boilers being financed (1,090). By 2006 however we still need to

  18. The effect of an active implementation of a disease management programme for chronic obstructive pulmonary disease on healthcare utilization--a cluster-randomised controlled trial.

    Science.gov (United States)

    Smidth, Margrethe; Christensen, Morten Bondo; Fenger-Grøn, Morten; Olesen, Frede; Vedsted, Peter

    2013-10-03

    The growing population living with chronic conditions calls for efficient healthcare-planning and effective care. Implementing disease-management-programmes is one option for responding to this demand. Knowledge is scarce about the effect of implementation processes and their effect on patients; only few studies have reported the effectiveness of disease-management-programmes targeting patients with chronic obstructive pulmonary disease (COPD). The objective of this paper was to determine the effect on healthcare-utilization of an active implementation model for a disease-management-programme for patients with one of the major multimorbidity diseases, COPD. The standard implementation of a new disease-management-programme for COPD was ongoing during the study-period from November 2008 to November 2010 in the Central Denmark Region. We wanted to test a strategy using Breakthrough Series, academic detailing and lists of patients with COPD. It targeted GPs and three hospitals serving approx. 60,000 inhabitants aged 35 or older and included interventions directed at professionals, organisations and patients. The study was a non-blinded block- and cluster-randomised controlled trial with GP-practices as the unit of randomisation. In Ringkoebing-Skjern Municipality, Denmark, 16 GP-practices involving 38 GPs were randomised to either the intervention-group or the control-group. A comparable neighbouring municipality acted as an external-control-group which included nine GP-practices with 25 GPs. An algorithm based on health-registry-data on lung-related contacts to the healthcare-system identified 2,736 patients who were alive at the end of the study-period. The population included in this study counted 1,372 (69.2%) patients who responded to the baseline questionnaire and confirmed their COPD diagnosis; 458 (33.4%) patients were from the intervention-group, 376 (27.4%) from the control-group and 538(39.2%) from the external-control-group. The primary outcome was

  19. Short-Term High-Fat Diet Increases Leptin Activation of CART Neurons and Advances Puberty in Female Mice.

    Science.gov (United States)

    Venancio, Jade Cabestre; Margatho, Lisandra Oliveira; Rorato, Rodrigo; Rosales, Roberta Ribeiro Costa; Debarba, Lucas Kniess; Coletti, Ricardo; Antunes-Rodrigues, Jose; Elias, Carol F; Elias, Lucila Leico K

    2017-11-01

    Leptin is a permissive factor for puberty initiation, participating as a metabolic cue in the activation of the kisspeptin (Kiss1)-gonadotropin-releasing hormone neuronal circuitry; however, it has no direct effect on Kiss1 neurons. Leptin acts on hypothalamic cocaine- and amphetamine-regulated transcript (CART) neurons, participating in the regulation of energy homeostasis. We investigated the influence of a short-term high-fat diet (HFD) on the effect of leptin on puberty timing. Kiss1-hrGFP female mice received a HFD or regular diet (RD) after weaning at postnatal day (PN)21 and were studied at PN28 and PN32. The HFD increased body weight and plasma leptin concentrations and decreased the age at vaginal opening (HFD, 32 ± 0.53 days; RD, 38 ± 0.67 days). Similar colocalization of neurokinin B and dynorphin in Kiss1-hrGFP neurons of the arcuate nucleus (ARC) was observed between the HFD and RD groups. The HFD increased CART expression in the ARC and Kiss1 messenger RNA expression in the anteroventral periventricular (AVPV)/anterior periventricular (Pe). The HFD also increased the number of ARC CART neurons expressing leptin-induced phosphorylated STAT3 (signal transducer and activator of transcription 3) at PN32. Close apposition of CART fibers to Kiss1-hrGFP neurons was observed in the ARC of both RD- and HFD-fed mice. In conclusion, these data reinforce the notion that a HFD increases kisspeptin expression in the AVPV/Pe and advances puberty initiation. Furthermore, we have demonstrated that the HFD-induced earlier puberty is associated with an increase in CART expression in the ARC. Therefore, these data indicate that CART neurons in the ARC can mediate the effect of leptin on Kiss1 neurons in early puberty induced by a HFD. Copyright © 2017 Endocrine Society.

  20. The HAT TRICK programme for improving physical activity, healthy eating and connectedness among overweight, inactive men: study protocol of a pragmatic feasibility trial.

    Science.gov (United States)

    Caperchione, Cristina M; Bottorff, Joan L; Oliffe, John L; Johnson, Steven T; Hunt, Kate; Sharp, Paul; Fitzpatrick, Kayla M; Price, Ryley; Goldenberg, S Larry

    2017-09-06

    Physical activity, healthy eating and maintaining a healthy weight are associated with reduced risk of cardiovascular disease, type 2 diabetes and cancer and with improved mental health. Despite these benefits, many men do not meet recommended physical activity guidelines and have poor eating behaviours. Many health promotion programmes hold little appeal to men and consequently fail to influence men's health practices. HAT TRICK was designed as a 12-week face-to-face, gender-sensitised intervention for overweight and inactive men focusing on physical activity, healthy eating and social connectedness and was delivered in collaboration with a major junior Canadian ice hockey team (age range 16-20 years). The programme was implemented and evaluated to assess its feasibility. This article describes the intervention design and study protocol of HAT TRICK. HAT TRICK participants (n=60) were men age 35 years, residing in the Okanagan Region of British Columbia, who accumulate 150 min of moderate to vigorous physical activity a week, with a body mass index of >25 kg/m 2 and a pant waist size of >38'. Each 90 min weekly session included targeted health education and theory-guided behavioural change techniques, as well as a progressive (ie, an increase in duration and intensity) group physical activity component. Outcome measures were collected at baseline, 12 weeks and 9 months and included the following: objectively measured anthropometrics, blood pressure, heart rate, physical activity and sedentary behaviour, as well as self-reported physical activity, sedentary behaviour, diet, smoking, alcohol consumption, sleep habits, risk of depression, health-related quality of life and social connectedness. Programme feasibility data (eg, recruitment, satisfaction, adherence, content delivery) were assessed at 12 weeks via interviews and self-report. Ethical approval was obtained from the University of British Columbia Okanagan Behavioural Research Ethics Board (reference no H

  1. ISOLDE PROGRAMME

    CERN Multimedia

    Fedosseev, V; Herfurth, F; Scheidenberger, C; Geppert, C; Gorges, C; Ratajczyk, T; Wiederhold, J C; Vogel, S; Munch, M K; Nieminen, P; Pakarinen, J J A; Lecesne, N; Bouzomita, H; Grinyer, J; Marques moreno, F M; Parlog, M; Blank, B A; Pedroza, J; Ghetta, V; Lozeva, R; Zacarias, S M; Guillemaud mueller, D S; Cottereau, E; Cheikh mhamed, M; Tusseau nenez, S; Tungate, G; Walker, P M; Smith, A G; Fitzpatrick, C; Dominik, W M; Karny, M; Ciemny, A A; Nyman, G H; Thies, R M A; Lindberg, S K G; Langouche, G F; Velten, P; Araujo escalona, V I; Boudreau, M; Domnanich, K A; Richter, D; Lutter, R J; Javaji, A; Engel, R Y; Wiehr, S; Nacher gonzalez, E; Jungclaus, A; Ribeiro jimenez, G; Marroquin alonso, I; Cal gonzalez, J; Paziy, V; Salsac, M; Murphy, C; Podolyak, Z F; Bajoga, A D; Butler, P; Pritchard, A; Colosimo, S J; Steer, A N; Fox, S P; Wadsworth, B A; Truesdale, V L; Al monthery, M; Bracco, A; Guttormsen, M S; Badea, M N; Calinescu, S; Ujeniuc, S; Cederkall, J A; Zemlyanoy, S; Donets, E D; Golovkov, M; Schweitzer, D K; Vranicar, A; Harrichunder, S; Ncube, M; Nannini, A; Strisovska, J; Wolf, E; Gerten, R F; Lehnert, J; Rainovski, G I; Pospisil, S; Datta pramanik, U; Benzoni, G; Fedorov, D; Maier, F M; Bonanni, A; Pfeiffer, B; Griesel, T; Wehner, L W; Mikkelsen, M; Recchia, F; Lenzi, S M; Smith, J F; Kelly, C M; Acosta sanchez, L A; Chavez lomeli, E R; De melo bandeira tavares, P M; Vieira, J M; Martins da silva, M A; Lima lopes, A M; Lopes leal, T J; Mader, J; Kessler, P; Laurent, B G; Schweikhard, L C; Marx, G H; Kulczycka, E; Komorowska, M; Da silva, M F; Goncalves marques, C P; Baptista peres, M A; Welander, J E; Reiter, P; Miller, C; Martin sanchez-cano, D; Wiens, A; Blazhev, A A; Braun, N; Cappellazzo, M V; Birkenbach, B; Gerst, R; Dannhoff, M F; Sithole, M J; Bilgier, B; Nardelli, S; Araujo mendes, C M; Agramunt ros, J; Valencia marin, E; Pantea, E; Hessberger, F P; Leduc, A J; Mitsuoka, S; Carbonari, A W; Buchegger, F J; Garzon camacho, A; Dapo, H; Papka, P; Stachura, M K; Stora, T; Marsh, B A; Thiboud, J A; Heylen, H; Antalic, S; Stahl, C; Bauer, C; Thurauf, M; Maass, B; Sturm, S; Boehm, C; Wolf, N R; Ways, M; Steinsberger, T P; Riisager, K; Ruotsalainen, P A; Bastin, B; Duval, F T; Penessot, G; Flechard, X D; Desrues, P; Giovinazzo, J; Kurtukian nieto, T; Ascher, P E L; Roccia, S; Matea, I; Croizet, H A G; Bonnin, C M; Morfouace, P; Smith, A J; Guin, R; Banerjee, D; Gunnlaugsson, H P; Ohtsubo, T; Zhukov, M V; Tengborn, E A; Welker, A; Giannopoulos, E; Dessagne, P; Juscamaita vivanco, Y; Da costa pereira, L M; Hustings, J; Yu, H; Kruecken, R; Nowak, A K; Jankowski, M; Cano ott, D; Galve lahoz, P; Murphy, A S J; Shand, C M; Jones, G D; Herzberg, R; Ikin, P; Revill, J P; Everett, C; Napoli, D R; Scarel, G; Larsen, A; Tornyi, T G; Pascu, S G; Stroe, L; Toma, S; Jansson, K; Dronjak fahlander, M; Krupko, S; Hurst, A M; Veskovic, M; Nikolov, J; Masenda, H; Sibanda, W N; Rocchini, M; Klimo, J; Deicher, M; Wichert, T; Kronenberg, J; Helmke, A; Meliani, Z; Ivanov, V S; Green, B L; Keatings, J M; Kuti, I; Halasz, Z; Henry, M O; Bras de sequeira amaral, V; Espirito santo, F; Da silva, D J; Rosendahl, S; Vianden, R J; Speidel, K; Agarwal, I; Faul, T; Kownacki, J M; Martins correia, J G; Lorenz, K; Costa miranda, S M; Granadeiro costa, A R; Zyabkin, D; Kotthaus, T; Pfeiffer, M; Gironi, L; Jensen, A; Romstedt, F; Constantino silva furtado, I; Heredia cardona, J A; Jordan martin, M D; Montaner piza, A; Zacate, M O; Plewinski, F; Mesli, A; Akakpo, E H; Pichard, A; Hergemoller, F; Neu, W; Fallis starhunter, J P; Voulot, D; Mrazek, J; Ugryumov, V; Savreux, R P; Kojouharov, I M; Kern, R O; Papst, O; Fitting, J; Lauer, M; Kirsebom, O S; Jensen, K L; Jokinen, A; Rahkila, P J; Hager, U D K; Konki, J P; Dubois, M; Orr, N A; Fabian, X; Huikari, J E; Goigoux, T; Magron, C; Zakari, A A; Maietta, M; Bachelet, C E M; Roussiere, B; Li, R; Canavan, R L; Lorfing, C; Foster, R M; Gislason, H P; Shayestehaminzadeh, S; Qi, B; Mukai, M; Watanabe, Y; Willmann, L; Kurcewicz, W; Wimmer, K; Meisel, Z P; Dorvaux, O; Nowacki, F; Koudriavtsev, I; Lievens, P; Delaure, B J P; Neyens, G; Ceruti, S; Bunka, M; Vermeulen, C; Umbricht, C A; De boer, J; Podadera aliseda, I; Alcorta moreno, M; Pesudo fortes, V; Zielinska, M; Korten, W; Wang, C H; Lotay, G J; Mason, P; Rice, S J; Regan, P H; Willenegger, L M; Andreev, A; Yavuzkanat, N; Hass, M; Kumar, V; Valiente dobon, J J; Crespo campo, L; Zamfir, N - V; Deleanu, D; Clisu, C; Jeppesen, H B; Wu, C; Pain, S D; Stracener, D W; Wuosmaa, A H; Szilner, S; Colovic, P; Matousek, V; Venhart, M; Birova, M; Li, X; Stuchbery, A E; Lellep, G M; Chakraborty, S; Leoni, S; Chupp, T; Yilmaz, C; Severin, G; Garcia ramos, J E; Newton, M E; Hadinia, B; Mc glynn, E; Monteiro de sena silvares de carvalho, I; Friedag, P; Figuera, P; Koos, V; Meot, V H; Pauwels, D B; Jancso, A; Srebrny, J; Alves, E J; David bosne, E; Bengtsson, L; Kalkuehler, M; Albers, M; Bharuth-ram, K; Akkus, B; Hemmingsen, L B S; Pedersen, J T; Dos santos redondo, L M; Rubio barroso, B; Algora, A; Kozlov, V; Mavela, D L; Mokhles gerami, A; Keeley, N; Bernardo da silva, E; Unzueta solozabal, I; Schell, J; Szybowicz, M; Yang, X; Plavec, J; Lassen, J; Johnston, K; Coquard, L; Bloch, T P; Bonig, E S; Stegmann, R; Ignatov, A; Paschalis, S; Fernandez martinez, G; Schilling, M; Habermann, T; Von hahn, R; Minaya ramirez, E E; Moore, I D; Wang, Y; Saastamoinen, A J; Grahn, T; Herzan, A; Stolze, S M; Clement, E; Dijon, A; Shornikov, A; Lienard, E; Gibelin, J D; Pain, C; Canchel, G; Simpson, G S; Latrasse, L P; Huang, W; Forest, D H; Billowes, J; Flanagan, K; Strashnov, I; Binnersley, C L; Sanchez poncela, M; Simpson, J; Morrall, P S; Grant, A F; Charisopoulos, S; Lagogiannis, A; Bhattacharya, C; Olafsson, S; Stepaniuk, M; Tornqvist, H T; Heinz, A M; White iv, E R; Courtin, S; Marechal, F; Da silva fenta, A E; De lemos lima, T A; Stryjczyk, M; Dockx, K; Haller, S; Rizzi, M; Reichert, S B; Bonn, J; Thirolf, P G; Garcia rios, A R; Gugliermina, V M; Cubero campos, M A; Sanchez tembleque, V; Benito garcia, J; Senoville, M; Mountford, D J; Gelletly, W; Alharbi, T S T; Wilson, E; Rigby, S V; Andreoiu, C; Paul, E S; Harkness, L J; Judson, D S; Wraith, C; Van esbroeck, K; Wadsworth, R; Cubiss, J G; Harding, R D; Vaintraub, S; Mandal, S K; Scarpa, D; Hoff, P; Syed naeemul, H; Borcea, R; Balabanski, D L; Marginean, R; Rotaru, F; Rudolph, D; Fahlander, C H; Chudoba, V; Kay, B P; Soic, N; Naidoo, D; Veselsky, M; Kliman, J; Raisanen, J A; Dietrich, M; Maung maung than, M M T; Reed, M W; Danchev, M T; Ray, J; Roy, M; Hammen, M; Capponi, L; Veghne csatlos, M M; Fryar, J; Mirzadeh vaghefi, S P; Trindade pereira, A M; De pinho oliveira, G N; Bakenecker, A; Tramm, C; Germic, V; Morel, P A; Kowalczyk, M; Matejska-minda, M; Wolinska-cichocka, M; Ringvall moberg, A; Mantovan, R; Fransen, C H; Radeck, F; Schneiders, D W; Steinbach, T; Vibenholt, J E; Magnussen, M J; Stevnhoved, H M; Comas lijachev, V; Dasenbrock-gammon, N M; Perkowski, J; O'neill, G G; Matveev, Y; Wegner, M; Liu, Z; Perez alvarez, T; Cerato, L; Radchenko, V; Molholt, T E; Tabares giraldo, J A; Srnka, D; Dlouhy, Z; Beck, D; Werner, V R; Homm, I; Eliseev, S; Blaum, K; Probst, M B; Kaiser, C J; Martin, J A; Refsgaard, J; Peura, P J; Greenlees, P T; Auranen, K; Delahaye, P; Traykov, E K; Perez loureiro, D; Mery, A A; Couratin, C; Tsekhanovich, I; Lunney, D; Gaulard, C V; Mottram, A D; Cullen, D M; Das, S K; Van de walle, J; Mazzocchi, C; Jonson, B N G; Woehr, A; Lesher, S R; Zuber, K T; Filippin, L; De witte, H J; Van den bergh, P A M; Raabe, R; Dirkx, D; Parnefjord gustafsson, F O A; Dunlop, R A; Tarasava, K; Gernhaeuser, R A; Weinzierl, W; Berger, C; Wendt, K; Achtzehn, T; Gottwald, T; Schug, M; Rossel, R E; Dominguez reyes, R R; Fraile prieto, L M; Briz monago, J A; Koester, U H; Bunce, M R; Bowry, M D; Nakhostin, M; Shearman, R; Cresswell, J R; Joss, D T; Gredley, A; Groombridge, D; Laird, A M; Aslanoglou, X; Siem, S; Weterings, J A; Renstrom, T; Szpak, B T; Luczkowski, M J; Ghita, D; Bezbakh, A; Soltz, R A; Bollmann, J; Bhattacharya, P; Roy, S; Rahaman, M A; Wlodarski, T; Carvalho soares, J; Barzakh, A; Schertz, F; Froemmgen, N E; Liberati, V; Foy, B E; Baptista barbosa, M; Weinheimer, C P; Zboril, M; Simon, R E; Popescu, L A; Czosnyka, T; Miranda jana, P A; Leimbach, D; Naskrecki, R; Plociennik, W A; Ruchowska, E E; Chiara, C J; Walters, W; Eberth, J H; Thomas, T; Thole, P; Queiser, M T; Lo bianco, G; D'amico, F; Muller, S; Sanchez alarcon, R M; Tain enriquez, J L; Orrigo, S E A; Orlandi, R; Masango, S; Plazaola muguruza, F C; Lepareur, N G; Fiebig, J M; Ceylan, N; Wildner, E; Kowalska, M; Malbrunot, S; Garcia ruiz, R F; Pallada, S; Slezak, M; Roeckl, E; Schrieder, G H; Ilieva, S K; Koenig, K L; Amoretti, M A; Lommen, J M; Fynbo, H O U; Weyer, G O P; Koldste, G T; Madsboll, K; Jensen, J H; Nieminen, A M; Reponen, M; Villari, A; Thomas, J; Saint-laurent, M; Sorlin, O H; Carniol, B; Pereira lopez, J; Grevy, S; Plaisir, C; Marie-jeanne, M J; Georgiev, G P; Etile, A M; Le blanc, F M; Verney, D; Stefan, G I; Assie, M; Suzuki, D; Guillot, J; Vazquez rodriguez, L; Campbell, P; Deacon, A N; Ware, T; Flueras, A; Xie, L; Banerjee, K; Piersa, M; Galaviz redondo, D; Johansson, H T; Schwarz, S; Toysa, A S; Aumont, J; Van duppen, P L E; Atanasov, D; Zadvornaya, A; Renaud, M A; Xu, Z; Garrett, P E; Rapisarda, E; Reber, J A; Mattolat, C F; Raeder, S; Habs, D; Vidal, M; Perez liva, M; Calvo portela, P; Ulla pedrera, F J; Wood, R T; Lalkovski, S; Page, R; Petri, M; Barton, C J; Nichols, A J; Vermeulen, M J; Bloor, D M; Henderson, J; Wilson, G L; De angelis, G; Buerger, A; Modamio hoybjor, V; Klintefjord, M L; Ingeberg, V W; Fornal, B A; Marginean, R; Sava, T; Kusoglu, A; Suvaila, R; Lica, R; Costache, C; Mihai, R; Ionescu, A; Baeck, T M; Hoffman, C R; Sedlak, M; Koskelo, O K; Kyaw myat, K M; Gladnishki, K A; Ganguly, B; Goncalves marques, J; Cardoso, S; Seliverstov, M; Niessen, B D; Gutt, L E; Chapman, R; Spagnoletti, P N; Lopes, C; De oliveira amorim, C; Batista lopes, C M; Araujo, J; Schielke, S J; Daugas, J R; Gaudefroy, L; Chevrier, R; Szunyogh, D M; Napiorkowski, P J; Wrzosek-lipska, K; Wahl, U; Catarino, N; Pereira carvalho alves de sequeira, M; Hess, H E; Holler, A; Bettermann, L; Geibel, K; Taprogge, J; Lewandowski, L T N; Manchado de sola, F; Cakirli mutlu, R B; Das gupta, S; Thulstrup, P W; Heinz, U; Nogwanya, T; Neidherr, D M; Morales lopez, A I; Gumenyuk, O; Peaker, A R; Wakabayashi, Y; Abrahams, K J; Martin montes, E J; Mach, H A; Souza ribeiro junior, I; He, J; Chalil, A; Xing, R; Dos santos augusto, R M; Giles, T J; Dorsival, A; Trujillo hernandez, J S; Kalaninova, Z; Andel, B; Venos, D; Kraemer, J; Saha, S; Neugart, R; Eronen, T O; Kreim, K D; Heck, M K; Goncharov, M; Karthein, J; Julin, R J; Eleon, C; Achouri, N L; Grinyer, G F; Fontbonne, C M; Alfaurt, P; Lynch, K M; Wilkins, S G; Brown, A R; Imai, N; Pomorski, M J; Janiak, L; Nilsson, T; Stroke, H H; Stanja, J; Dangelser, E; Heenen, P; Godefroid, M; Mallion, S N; Gins, W A M; Stegemann, S T; Koszorus, A; Mcnulty, J F; Lin, P; Ohlert, C M; Schwerdtfeger, W; Tengblad, O; Becerril reyes, A D; Perea martinez, A; Martinez perez, M C; Margerin, V; Rudigier, M; Alexander, T D; Patel, Z V; Hammond, N; Wearing, F; Patel, A; Jenkins, D G; Corradi, L; Galtarossa, F; Debernardi, A; Giacoppo, F; Tveten, G M; Malatji, K L; Krolas, W A; Stanoiu, M A; Rickert, E U; Ter-akopian, G; Cline, D; Riihimaeki, I A; Simon, K D; Wagner, F E; Turker, M; Neef, M H; Coombes, B J; Jakubek, J; Vagena, E; Bottoni, S; Nishimura, K; Correia, J; Rodrigues valdrez, C J; Molkanov, P; Adhikari, R; Ostrowski, A N; Hallmann, O; Scheck, M; Wady, P T; Lane, J; Krasznahorkay, A J; Kunne sohler, D; Meaney, A J; Hochschulz, F; Roig, O; Behan, C C; Kargoll, S; Kemnitz, S; Carvalho teixeira, R C; Redondo cubero, A; Tallarida, G; Kaczarowski, R; Finke, F; Linnemann, A; Altenkirch, R; Saed-samii, N; Ansari, S H; Dlamini, W B; Adoons, V N; Ronning, C R; Wiedeking, M; Herlert, A J; Mehl, C V; Judge, S M; Gaertner, D; Divinskyi, S; Karabasov, M O; Zagoraios, G; Boztosun, I; Van zyl, J J; Catherall, R; Lettry, J; Wenander, F J C; Zakoucky, D; Catchen, G L; Noertershaeuser, W; Kroell, T; Leske, J; Shubina, D; Murray, I M; Pancin, J; Delaunay, F; Poincheval, J J L; Audirac, L L; Gerbaux, M T; Aouadi, M; Sole, P G P; Fallot, M P; Onillon, A; Duchemin, C; Formento cavaier, R; Audi, G; Boukhari, A; Lau, C; Martin, J A; Barre, N H; Berry, T A; Procter, T J; Bladen, L K; Axiotis, M; Muto, S; Jeong, S C; Hirayama, Y; Korgul, A B; Minamisono, K; Bingham, C R; Aprahamian, A; Bucher, B M; Severijns, N; Huyse, M L; Ferrer garcia, R; Verlinde, M N S; Romano, N; Maugeri, E A; Klupp, S C; Dehn, M H; Heinke, R M; Naubereit, P; Maira vidal, A; Vedia fernandez, M V; Ibanez garcia, P B; Bruyneel, B J E; Materna, T; Hadynska-klek, K; Al-dahan, N; Alazemi, N; Carroll, R J; Babcock, C; Patronis, N; Eleme, Z; Dhal, A; Sahin, E; Goergen, A; Maj, A; Bednarczyk, P A; Borcea, C; Negoita, F; Suliman, G; Marginean, N M; Sotty, C O; Negret, A L; Nae, S A; Nita, C; Golubev, P I; Knyazev, A; Jost, C U; Petrik, K; Vaeyrynen, S A; Dracoulis, G D; Uher, J; Fernandez dominguez, B; Chakraborty, P; Avigo, R; Falahat, S; Lekovic, F; Dorrer, H J; Mengoni, D; Derkx, X; Angus, L J; Sandhu, K S; Gregor, E; Kelly, N A; Byrne, D J; Haas, H; Lourenco, A A; Sousa pereira, S M; Sousa, J B; De melo mendonca, T M; Tavares de sousa, C; Guerreiro dos santos oliveira custodio, L M; Da rocha rodrigues, P M; Yamaguchi, T; Thompson, P C; Rosenbusch, M; Wienholtz, F; Fischer, P; Iwanicki, J S; Rusek, K M; Hanstorp, D; Vetter, U; Wolak, J M; Park, S H; Warr, N V; Doornenbal, P C; Imig, A; Seidlitz, M; Moschner, K; Vogt, A; Kaya, L; Martel bravo, I; Orduz, A K; Serot, O; Majola, S N; Litvinov, Y; Bommert, M; Hensel, S; Markevich, V; Nishio, K; Ota, S; Matos, I; Zenkevich, A; Picado sandi, E; Forstner, O; Hu, B; Ntshangase, S S; Sanchez-segovia, J

    2002-01-01

    The experiments aim at a broad exploration of the properties of atomic nuclei far away from the region of beta stability. Furthermore, the unique radioactive beams of over 60~elements produced at the on-line isotope separators ISOLDE-2 and ISOLDE-3 are used in a wide programme of atomic, solid state and surface physics. Around 300 scientists are involved in the project, coming from about 70 laboratories. \\\\ \\\\ The electromagnetic isotope separators are connected on-line with their production targets in the extracted 600 MeV proton or 910~MeV Helium-3 beam of the Synchro-Cyclotron. Secondary beams of radioactive isotopes are available at the facility in intensities of 10$^1

  2. A theory evaluation of an induction programme

    Directory of Open Access Journals (Sweden)

    Kenrick Hendricks

    2012-07-01

    Full Text Available Orientation: An induction programme is commonly used to help new employees understand their job within the organisation. Research purpose: The main aim of this study was to examine whether or not the programme theory of an induction programme was plausible and would lead to the intended outcomes as described by the programme manager. Motivation for the study: Induction training is one of the most common training programmes in an organisation. However, there is little research to evaluate whether or not the activities of an induction programme will lead to the intended outcomes of such a programme. Research design, approach and method: This theory evaluation used a descriptive design. One hundred and thirteen employees of a media company completed a ten-item, five-point Likert scale which measured their perceptions of the programme’s outcome, identification with the organisation and intentions to stay with the organisation. Main findings: From this theory evaluation it was apparent that an induction programme based on an implausible programme theory could be problematic. An implausible programme theory affects the design of the programme activities and unsuitable activities may not deliver the desired outcomes. Practical/managerial implications: The intention of the evaluation is to guide human resource managers through a process of replacing an implausible programme theory with one that is plausible, and which ensures better alignment of programme activities and outcomes. Contribution/value-add: The evaluators showed how a plausible programme theory could improve programme design. This redesigned induction programme may lead to benefits, such as staff retention and company identification, rather than the vague assumption that it has been conforming to a legal obligation.

  3. Fusion technology programme

    International Nuclear Information System (INIS)

    Finken, D.

    1985-10-01

    KfK is involved in the European Fusion Programme predominantly in the NET and Fusion Technology part. The following fields of activity are covered: Studies for NET, alternative confinement concepts, and needs and issues of integral testing. Research on structural materials. Development of superconducting magnets. Gyrotron development (part of the Physics Programme). Nuclear technology (breeding materials, blanket design, tritium technology, safety and environmental aspects of fusion, remote maintenance). Reported here are status and results of work under contracts with the CEC within the NET and Technology Programme. The aim of the major part of this R and D work is the support of NET, some areas (e.g. materials, safety and environmental impact, blanket design) have a wider scope and address problems of a demonstration reactor. In the current working period, several new proposals have been elaborated to be implemented into the 85/89 Euratom Fusion Programme. New KfK contributions relate to materials research (dual beam and fast reactor irradiations, ferritic steels), to blanket engineering (MHD-effects) and to safety studies (e.g. magnet safety). (orig./GG)

  4. Exchange and fellowship programme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1959-04-15

    By February 1959, the IAEA had received and considered nearly 300 nominations from 31 countries for nuclear science fellowships. More than 200 of the candidates - from 29 countries - had been selected for placement in centres of training in 21 countries. The programme covers three types of training: 1. General techniques training: to develop skills in the use of some fundamental techniques in the field of nuclear energy; 2. Specialist training: to prepare specialists in the theoretical and experimental aspects of the science and technology of nuclear energy; 3. Research training: to provide advanced training, including active participation in research work; this is for persons potentially qualified to develop and carry out research programmes in the basic sciences and engineering. The duration of training varies from some weeks to five or six years. The long-duration training is given at universities or educational establishments of university level, and is of special interest to Member States lacking personnel with the requisite university education. Under its 1959 exchange and fellowship programme, the Agency will be in a position to award over 400 fellowships. Some of these will be paid out of the Agency's operating fund, while 130 fellowships have been offered directly to IAEA by Member States for training at their universities or institutes. There are two new features in the Agency's 1959 programme. One provides for fellowships for scientific research work, the other is the exchange of specialists

  5. Experience from the Inspection of Licensees' Outage Activities, Including Fire Protection Programmes, Event Response Inspections, and the Impact of the Fukushima Daiichi NPP Accident on Inspection Programmes. Workshop Proceedings, Chattanooga, Tennessee, United States, 7-10 April 2014

    International Nuclear Information System (INIS)

    2014-10-01

    The main purpose of the workshop was to provide a forum of exchange of information on the regulatory inspection activities. Participants had the opportunity to meet with their counterparts from other countries and organisations to discuss current and future issues on the selected topics. They developed conclusions regarding these issues and hopefully, identified methods to help improve their own inspection programmes. The NEA Committee on Nuclear Regulatory Activities (CNRA) believes that an essential factor in ensuring the safety of nuclear installations is the continuing exchange and analysis of technical information and data. To facilitate this exchange the Committee has established working groups and groups of experts in specialised topics. The Working Group on Inspection Practices (WGIP) was formed in 1990 with the mandate '..to concentrate on the conduct of inspections and how the effectiveness of inspections could be evaluated..'. The WGIP facilitates the exchange of information and experience related to regulatory safety inspections between CNRA member countries. These proceedings cover the 12. International Workshop held by WGIP on regulatory inspection activities. This workshop, which is the twelfth in a series, along with many other activities performed by the Working Group, is directed towards this goal. The consensus from participants at previous workshops, noted that the value of meeting with people from other inspection organisations was one of the most important achievements. The focus of this workshop was on experience gained from regulatory inspection activities in three areas: - Inspection of Outage Activities Including Fire Protection Programmes. - Event Response Inspections. - The Impact of Inspection Programmes of the Fukushima Daiichi Nuclear Power Plant (NPP) Accident. The main objectives of the WGIP workshops are to enable inspectors to meet with inspectors from other organisations, to exchange information regarding regulatory inspection

  6. A community-based multilevel intervention for smoking, physical activity and diet: short-term findings from the Community Interventions for Health programme in Hangzhou, China.

    Science.gov (United States)

    Lv, Jun; Liu, Qing-Min; Ren, Yan-Jun; He, Ping-Ping; Wang, Sheng-Feng; Gao, Fang; Li, Li-Ming

    2014-04-01

    To assess the short-term impact of a comprehensive, community-based multilevel intervention on knowledge, beliefs and practices with respect to smoking, physical activity and diet in Hangzhou, China. A non-randomised, controlled, before-after quasi-experimental trial was conducted in two intervention areas and one comparison area. The intervention built on a socioecological framework and took place across four settings: neighbourhoods, schools, workplaces and community health centres. Two independent cross-sectional surveys of adults aged 18-64 years at baseline and a subsequent follow-up were conducted in 2008/2009 and 2011 in the intervention and comparison areas. A 2-year intervention programme was begun in mid-2009 and continued until mid-2011. A total of 2016 adults at baseline and 2016 adults at follow-up completed the survey. Over the 2-year intervention period, the intervention areas showed a statistically significant decline (25.2% vs 18.7%, psmoking compared with the comparison area (18.0% vs 16.4%, p=0.343). The proportion of individuals who had noticed anyone smoking in any of nine locations in the previous 30 days demonstrated a statistically significant decline in the intervention (78.9% vs 66.5%, psmoking and physical activity but not diet. A community-based multilevel intervention programme is feasible in urban China.

  7. Activities of the Sofia EC Energy Center in the framework of the THERMIE programme. Dejnost na centyra po energetika na EO v Sofia v ramkite na programata TERMIE

    Energy Technology Data Exchange (ETDEWEB)

    Latinski, K

    1993-01-01

    The European Community Energy Center in Sofia is responsible for the EC implementation of the THERMIE programme. The programme's activities are promotion and dissemination of existing European technologies leading to better energy management and covering the fields of rational use of hydrocarbons, solid fuels and renewable energy sources. Application of these technologies would lead to substantial energy savings resulting in significant financial and environmental benefits. During its one-year operation the EC Energy Centre has organized and performed specific action as energy audits (food and beverage industrial units and buildings), demonstration projects (local heating control in buildings, diesel engine regulation of buses), training courses and seminars (in energy management and in space heating measuring and regulation), workshops (energy conservation in buildings, the bricks and clays sector and the food and beverage sector) and studies (wind energy potential, 'clean' coal technologies potential). Some of these actions have had very encouraging results showing potential energy savings of the order of 10-20% just by application of simple measures and with small additional investment. The activities of the EC Energy Centre in the coming year aimed at electricity savings along the entire line of electricity generation, transmission and consumption are outlined. (author).

  8. Programme budget 1981

    International Nuclear Information System (INIS)

    1980-01-01

    There are 11 main fields of KfK R + D activities which are connected with one or more of the research goals of a) assurance of nuclear fuel supply, b) nuclear waste management, c) safety of nuclear facilities, d) basic research and research on new technologies. The scientific and technical tasks connected with these goals in 1981 and on a medium-term basis as well as the financial requirements are presented in the programme budget. (orig.) [de

  9. Eel Kisspeptins: Identification, Functional Activity, and Inhibition on both Pituitary LH and GnRH Receptor Expression

    Directory of Open Access Journals (Sweden)

    Jérémy Pasquier

    2018-01-01

    Full Text Available The European eel (Anguilla anguilla presents a blockade of sexual maturation at a prepubertal stage due to a deficient production of gonadotropins. We previously initiated, in the eel, the investigation of the kisspeptin system, one of the major gatekeepers of puberty in mammals, and we predicted the sequence of two Kiss genes. In the present study, we cloned and sequenced Kiss1 and Kiss2 cDNAs from the eel brain. The tissue distributions of Kiss1 and Kiss2 transcripts, as investigated by quantitative real-time PCR, showed that both genes are primarily expressed in the eel brain and pituitary. The two 10-residue long sequences characteristic of kisspeptin, eel Kp1(10 and Kp2(10, as well as two longer sequences, predicted as mature peptides, eel Kp1(15 and Kp2(12, were synthesized and functionally analyzed. Using rat Kiss1 receptor-transfected Chinese hamster ovary cells, we found that the four synthesized eel peptides were able to induce [Ca2+]i responses, indicating their ability to bind mammalian KissR-1 and to activate second messenger pathways. In primary culture of eel pituitary cells, all four peptides were able to specifically and dose-dependently inhibit lhβ expression, without any effect on fshβ, confirming our previous data with heterologous kisspeptins. Furthermore, in this eel in vitro system, all four peptides inhibited the expression of the type 2 GnRH receptor (gnrh-r2. Our data revealed a dual inhibitory effect of homologous kisspeptins on both pituitary lhβ and gnrh-r2 expression in the European eel.

  10. The IAEA co-ordinated research programme on activation cross sections for the generation of long-lived radionuclides of importance in fusion reactor technology. Final report

    International Nuclear Information System (INIS)

    Pashchenko, A.B.

    1997-07-01

    The present report summarizes the final results of the IAEA Co-ordinated Research Programme on ''Activation Cross Section for the Generator of Long-lived Radionuclides of Importance in Fusion Reactor Technology''. The goal of the CRP was to obtain reliable information (experimental and evaluated) for 16 long-lived activation reactions of special importance to fusion reactor technology. By limiting the scope of the CRP to just 16 reactions it was possible to establish a very effective focus to the joint effort of many laboratories that has led to the generation of a set of valuable new data which provide satisfactory answers to several questions of technological concern to fusion. (author). 11 refs, 5 tabs

  11. ADS National Programmes: China

    International Nuclear Information System (INIS)

    2015-01-01

    In China the conceptual study of an ADS concept which lasted for about five years ended in 1999. As one project of the National Basic Research Programme of China (973 Programme) in energy domain, which is sponsored by the China Ministry of Science and Technology (MOST), a five year programme of fundamental research of ADS physics and related technology was launched in 2000 and passed national review at the end of 2005. From 2007, another five year 973 Programme Key Technology Research of Accelerator Driven Subcritical System for Nuclear waste Transmutation started. The research activities were focused on HPPA physics and technology, reactor physics of external source driven subcritical assembly, nuclear data base and material study. For HPPA, a high current injector consisting of an ECR ion source, LEBT and an RFQ accelerating structure of 3.5 MeV has been built and were being improved. In reactor physics study, a series of neutron multiplication experimental study has been carrying out. The VENUS I facility has been constructed as the basic experimental platform for neutronics study in ADS blanket. VENUS I a zero power subcritical neutron multiplying assembly driven by external neutron produced by a pulsed neutron generator or 252Cf neutron source. The theoretical, experimental and simulation studies on nuclear data, material properties and nuclear fuel circulation related to ADS are carried out in order to provide the database for ADS system analysis. China Institute of Atomic Energy (CIAE), Institute of High Energy Physics (IHEP) and other Chinese institutes carried out the MOST project together. Besides CIAE, China Academy of Science (CAS) pays more and more attention to Advanced Nuclear Fuel Cycles (ANFC). A large programme of ANFC, including ADS and Th based nuclear fuel cycle, has been launched by CAS

  12. The (cost-effectiveness of an individually tailored long-term worksite health promotion programme on physical activity and nutrition: design of a pragmatic cluster randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Burdorf Alex

    2007-09-01

    Full Text Available Abstract Background Cardiovascular disease is the leading cause of disability and mortality in most Western countries. The prevalence of several risk factors, most notably low physical activity and poor nutrition, is very high. Therefore, lifestyle behaviour changes are of great importance. The worksite offers an efficient structure to reach large groups and to make use of a natural social network. This study investigates a worksite health promotion programme with individually tailored advice in physical activity and nutrition and individual counselling to increase compliance with lifestyle recommendations and sustainability of a healthy lifestyle. Methods/Design The study is a pragmatic cluster randomised controlled trial with the worksite as the unit of randomisation. All workers will receive a standard worksite health promotion program. Additionally, the intervention group will receive access to an individual Health Portal consisting of four critical features: a computer-tailored advice, a monitoring function, a personal coach, and opportunities to contact professionals at request. Participants are employees working for companies in the Netherlands, being literate enough to read and understand simple Internet-based messages in the Dutch language. A questionnaire to assess primary outcomes (compliance with national recommendations on physical activity and on fruit and vegetable intake will take place at baseline and after 12 and 24 months. This questionnaire also assesses secondary outcomes including fat intake, self-efficacy and self-perceived barriers on physical activity and fruit and vegetable intake. Other secondary outcomes, including a cardiovascular risk profile and physical fitness, will be measured at baseline and after 24 months. Apart from the effect evaluation, a process evaluation will be carried out to gain insight into participation and adherence to the worksite health promotion programme. A cost-effectiveness analysis and

  13. Exploring physical activity behaviour - needs for and interest in a technology-delivered, home-based exercise programme among patients with intermittent claudication.

    Science.gov (United States)

    Cornelis, Nils; Buys, Roselien; Fourneau, Inge; Dewit, Tijl; Cornelissen, Véronique

    2018-02-01

    Supervised walking is a first line therapy in peripheral arterial disease (PAD) with complaints of intermittent claudication. However, uptake of supervised programmes is low. Home-based exercise seems an appealing alternative; especially since technological advances, such as tele-coaching and tele-monitoring, may facilitate the process and support patients when adopting a physically active lifestyle. To guide the development of such an intervention, it is important to identify barriers of physical activity and the needs and interests for technology-enabled exercise in this patient group. PAD patients were recruited at the vascular centre of UZ Leuven (Belgium). A questionnaire assessing PA (SF-International Physical Activity Questionnaire), barriers to PA, and interest in technology-supported exercise (Technology Usage Questionnaire) was completed. Descriptive and correlation analyses were performed. Ninety-nine patients (76 men; mean age 69 years) completed the survey. Physical activity levels were low in 48 %, moderate in 29 %, and high in 23 %. Intermittent claudication itself is the most important barrier for enhanced PA, with most patients reporting pain (93 %), need for rest (92 %), and obstacles worsening their pain (74 %) as barriers. A total of 93 % participants owned a mobile phone; 76 % had Internet access. Eighty-seven reported the need for an exercise programme, with 67 % showing interest in tele-coaching to support exercise. If technology was available, three-quarter stated they would be interested in home-based tele-coaching using the Internet (preferably e-mails, 86 %); 50 % via mobile phone, 87 % preferred text messages. Both were inversely related to age (rpb = 0.363 and rpb = 0.255, p < 0.05). Acquaintance with elastic bands or gaming platforms was moderate (55 and 49 %, respectively), but patients were interested in using them as alternatives (84 and 42 %). Interest in platforms was age-dependent (rs = -0.508, p < 0.01). PAD patients show

  14. Radon programme: presence and future

    International Nuclear Information System (INIS)

    Hulka, J.

    2009-01-01

    In this presentation an overview of radon programme experiences is presented. The paper summarises national radon policy, national programmes, legislation, the role of preventive measures and interventions with respect to existing and future exposure and knowledge of radon risk, problems of remediation strategies, practical protection in dwellings, radon measurements strategies, progress in radon measurement of an individual house (radon diagnosis), radon mapping process and sense of delineation of radon prone areas, natural radioactivity of building materials and radioactivity in public water and their role in the radon programme, public awareness on radon issue and publicity campaign. Some research activities are proposed aiming at effective solutions of radon issues in future

  15. A Statistical Programme Assignment Model

    DEFF Research Database (Denmark)

    Rosholm, Michael; Staghøj, Jonas; Svarer, Michael

    When treatment effects of active labour market programmes are heterogeneous in an observable way  across the population, the allocation of the unemployed into different programmes becomes a particularly  important issue. In this paper, we present a statistical model designed to improve the present...... duration of unemployment spells may result if a statistical programme assignment model is introduced. We discuss several issues regarding the  plementation of such a system, especially the interplay between the statistical model and  case workers....

  16. Electrostatics Explains the Position-Dependent Effect of G⋅U Wobble Base Pairs on the Affinity of RNA Kissing Complexes.

    Science.gov (United States)

    Abi-Ghanem, Josephine; Rabin, Clémence; Porrini, Massimiliano; Dausse, Eric; Toulmé, Jean-Jacques; Gabelica, Valérie

    2017-10-06

    In the RNA realm, non-Watson-Crick base pairs are abundant and can affect both the RNA 3D structure and its function. Here, we investigated the formation of RNA kissing complexes in which the loop-loop interaction is modulated by non-Watson-Crick pairs. Mass spectrometry, surface plasmon resonance, and UV-melting experiments show that the G⋅U wobble base pair favors kissing complex formation only when placed at specific positions. We tried to rationalize this effect by molecular modeling, including molecular mechanics Poisson-Boltzmann surface area (MMPBSA) thermodynamics calculations and PBSA calculations of the electrostatic potential surfaces. Modeling reveals that the G⋅U stabilization is due to a specific electrostatic environment defined by the base pairs of the entire loop-loop region. The loop is not symmetric, and therefore the identity and position of each base pair matters. Predicting and visualizing the electrostatic environment created by a given sequence can help to design specific kissing complexes with high affinity, for potential therapeutic, nanotechnology or analytical applications. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. A Self-Management Programme of Activity Coping and Education - SPACE for COPD(C) - in primary care: The protocol for a pragmatic trial.

    Science.gov (United States)

    Bourne, Claire LA; Kanabar, Pratiksha; Mitchell, Katy; Schreder, Sally; Houchen-Wolloff, Linzy; Bankart, M John G; Apps, Lindsay; Hewitt, Stacey; Harvey-Dunstan, Theresa; Singh, Sally J

    2017-07-10

    National guidance for chronic obstructive pulmonary disease (COPD) suggests that self-management support be provided for patients. Our institution has developed a standardised, manual-based, supported self-management programme: Self-Management Programme of Activity Coping and Education (SPACE for COPD(C)). SPACE was previously piloted on a 1-2-1 basis, delivered by researchers, to individuals with COPD. Discussions with stakeholders highlighted considerable interest in delivering the SPACE for COPD(C) intervention as a group-based self-management programme facilitated by healthcare professionals (HCPs) in primary care settings. The study aims are to explore the feasibility, acceptability and efficacy for the intervention to be delivered and supported by HCPs and to examine whether group-based delivery of SPACE for COPD(C), with sustained support, improves patient outcomes following the SPACE for COPD(C) intervention. A prospective, multi-site, single-blinded randomised controlled trial (RCT) will be conducted, with follow-up at 6 and 9 months. Participants will be randomly assigned to either the control group (usual care) or intervention group (a six-session, group-based SPACE for COPD(C)self-management programme delivered over 5 months). The primary outcome is change in COPD assessment test at 6 months.A discussion session will be conducted with HCPs who deliver the intervention to discuss and gain insight into any potential facilitators/barriers to implementing the intervention in practice. Furthermore, we will conduct semi-structured focus groups with intervention participants to understand feasibility and acceptability. All qualitative data will be analysed thematically. The project has received a favourable opinion from South Hampshire B Research Ethics Committee, REC reference: 14/SC/1169 and full R&D approval from the University Hospitals of Leicester NHS Trust: 152408.Study results will be disseminated through appropriate peer-reviewed journals, national

  18. Research activities on high temperature gas-cooled rectors (HTRs) in the fifth EURATOM RTD framework programme

    International Nuclear Information System (INIS)

    Martin-Bermejo, J.; Hugon, M.

    2001-01-01

    One of the areas of research of the nuclear fission key action of the Fifth EURATOM RTD Framework Programme (FP5) is safety and efficiency of future systems, which has as an objective to investigate and evaluate new or revisited concepts for nuclear energy that offer potential longer-term benefits in terms of cost, safety, waste management, use of fissile material, less risk of diversion and sustainability. After the first call for proposals of FP5, several projects related to high temperature gas-cooled reactors (HTRs) were retained by the European Commission (EC) services. They address important issues such as HTR fuel technology, HTR fuel cycle and HTR materials. In the next call for proposals (deadline January 2001) the EC expects other important HTR-related items not covered by the first call (e.g. power conversion systems and system analysis) to be addressed. The EC also expects proposals for strategy studies and/or thematic networks on the assessment of applications of nuclear energy other than generation of electricity via hydrogen production. (authors)

  19. Developing the necessary infrastructure. Chapter 1; IAEA activities in support of countries considering embarking on Nuclear Power Programme

    International Nuclear Information System (INIS)

    Akira, O.

    2010-01-01

    The IAEA supports in a variety of ways in establishing an appropriate infra-structure necessary to secure safe and reliable operation and still maintaining the international safeguards regime, especially in developing countries which are considering introduction of nuclear power programme. The TC projects to support introduction of nuclear power has been formulated and its number increased significantly recently. Various guidance documents have been published by the IAEA recently to enable progressive development of national infrastructure. The IAEA guidance documents constitute a basis of advises to newcomer countries. The recently formulated important mission is INIR mission to review the status of national infrastructure in the context of measuring the distance to the expected milestone. Finally, it is expected that the newcomers would make informed decision-making on going to nuclear power by fully understanding the necessary obligations and national long-term commitment, by confirming viability of nuclear power options in the country's energy plan through Energy Planning and long-term strategic assessment using IAEA guidance and tools

  20. Bioergia Research Programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D.

    1997-12-31

    The main objectives of Finland`s Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs.

  1. Bioergia Research Programme

    Energy Technology Data Exchange (ETDEWEB)

    Asplund, D

    1998-12-31

    The main objectives of Finland`s Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs.

  2. Bioergia Research Programme

    International Nuclear Information System (INIS)

    Asplund, D.

    1997-01-01

    The main objectives of Finland's Bioenergia Research Programme are (1) To develop new methods of producing biofuels which can compete with imported fuels, demonstrating the most promising production methods through pilot schemes, (2) To develop and demonstrate 3 - 4 new pieces of equipment or methods connected with handling and using bioenergy, (3) To produce basic information on conversion techniques and evaluate the quality, usability and environmental impacts of the products as well as the overall economy of the entire production chain and to create 2-3 conversion methods for follow-up development by industry. The principle research areas are (1) Development of production technology for wood-derived fuels, (2) Peat production, (3) The use of bioenergy and (4) Biomass conversion. This conference paper discusses the results obtained so far and reviews in some detail the activities of the programme. 3 figs., 3 tabs

  3. Effects of a predefined mini-trampoline training programme on balance, mobility and activities of daily living after stroke: a randomized controlled pilot study.

    Science.gov (United States)

    Miklitsch, Claudia; Krewer, Carmen; Freivogel, Susanna; Steube, Diethard

    2013-10-01

    To investigate the effects of a predefined mini-trampoline therapy programme for increasing postural control, mobility and the ability to perform activities of daily living after stroke. Randomized non-blinded controlled pilot study. Neurological rehabilitation hospital. First-time stroke; age 18-80 years; independent standing ability for a minimum of 2 minutes. Patients were randomized into two groups: the mini-trampoline group (n = 20) received 10 sessions of balance training using the mini-trampoline over three weeks. The patients of the control group (n =20) participated 10 times in a group balance training also over three weeks. Postural control (Berg Balance Scale, BBS), mobility and gait endurance (timed 'up and go' test, TUG; 6-minute walk test, 6MWT) and the ability to perform activities of daily living (Barthel Index, BI). Measurements were undertaken prior to and after the intervention period. Both groups were comparable before the study. The mini-trampoline group improved significantly more in the BBS (P = 0.003) compared to the control group. Mean or median differences of both groups showed improvements in the TUG 10.12 seconds/7.23 seconds, the 6MWT 135 m/75 m and the BI 20 points/13 points for the mini-trampoline and control group, respectively. These outcome measurements did not differ significantly between the two groups. A predefined mini-trampoline training programme resulted in significantly increased postural control in stroke patients compared to balance training in a group. Although not statistically significant, the mini-trampoline training group showed increased improvement in mobility and activities of daily living. These differences could have been statistically significant if we had investigated more patients (i.e. a total sample of 84 patients for the TUG, 98 patients for the 6MWT, and 186 patients for the BI).

  4. Role Models of Australian Female Adolescents: A Longitudinal Study to Inform Programmes Designed to Increase Physical Activity and Sport Participation

    Science.gov (United States)

    Young, Janet A.; Symons, Caroline M.; Pain, Michelle D.; Harvey, Jack T.; Eime, Rochelle M.; Craike, Melinda J.; Payne, Warren R.

    2015-01-01

    In light of the importance attributed to the presence of positive role models in promoting physical activity during adolescence, this study examined role models of adolescent girls and their influence on physical activity. Seven hundred and thirty two girls in Years 7 and 11 from metropolitan and non-metropolitan regions of Victoria, Australia,…

  5. An evidence-based Physical Activity and Fitness Programme for Ageing Adults with Intellectual Disabilities : Development, implementation and health effects

    NARCIS (Netherlands)

    M. van Schijndel-Speet (Marieke)

    2015-01-01

    markdownabstractIn this study, extremely low physical activity and fitness levels among older adults with intellectual disabilities were demonstrated. Although the importance of physical activity for health has been recognised in the field of people with ID, only few welldesigned studies with a

  6. The effectiveness of a physical activity stimulation programme for children with cerebral palsy on social participation, self-perception and quality of life: a randomized controlled trial.

    Science.gov (United States)

    Van Wely, Leontien; Balemans, Astrid Cj; Becher, Jules G; Dallmeijer, Annet J

    2014-10-01

    To determine the effects of a six-month physical activity stimulation programme on social participation, self-perception and quality of life in children with cerebral palsy. Multicentre randomized controlled trial with concealed allocation, blinded assessments and intention-to-treat analysis. Paediatric physiotherapy practices, special schools for children with a disability, and the child's own home. Forty-nine children with spastic cerebral palsy (28 male), aged 7-13 years, able to walk with and without walking aids. The intervention group followed a six-month physical activity stimulation programme involving counselling through motivational interviewing, home-based physiotherapy and four months of fitness training. The control group continued regular paediatric physiotherapy. Outcomes included social participation in domestic life, social participation in recreation and leisure (Life-Habits for Children questionnaire and Children's Assessment of Participation and Enjoyment questionnaire), self-perception (Harter's Self-Perception Profile for Children) and parent-reported quality of life (Cerebral Palsy Quality of Life Questionnaire). Assessments were performed at baseline, at six months (except quality of life) and at twelve months. Intervention resulted in a positive effect on social participation in domestic life at twelve months (mean between-group difference = 0.9, 95% confidence interval (CI) = 0.1 to 1.7 [1-10 scale], P = 0.03), but not at six months. No significant effects were found for social participation in recreation and leisure, self-perception at six months and twelve months or for quality of life at twelve months. The combination of counselling, home-based physiotherapy and fitness training was not effective in improving social participation in recreation and leisure, self-perception or quality of life, but did show a potential for improving social participation in domestic life over the longer term. © The Author(s) 2013.

  7. Family leisure-time physical activities – results of the “Juniors for Seniors” 15-week intervention programme

    Directory of Open Access Journals (Sweden)

    Pluta Beata

    2017-12-01

    Full Text Available Study aim: Both adequate time and quality time are important for the wellbeing of a family. The study evaluated the effective­ness of a 15-week family-based physical activity (PA intervention entitled “Junior for Seniors”. It included both children and parents. The paper focuses on an important topic - family-based leisure-time physical activity (LTPA. It is set in Polish primary schools, which is a novel approach. Regular physical activity for young people and their parents improves health and fitness including strength and endurance, promotes development of healthy bones and muscles, helps control weight and in­creases self-esteem.

  8. Why some do but most don't. Barriers and enablers to engaging low-income groups in physical activity programmes: a mixed methods study

    Directory of Open Access Journals (Sweden)

    Fox Kenneth R

    2011-06-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These chronic conditions are most pronounced in economically disadvantaged groups where physical activity levels are consistently lower, yet this group is particularly difficult to recruit and retain in physical activity programmes. This study examined the perceptions of participants, non-participants, and exercise leaders in a low-income area regarding barriers, motives, and enabling factors for organised physical activity with a view to improving recruitment and retention. Methods A mixed methods research approach was adopted to guide data collection and analysis. A survey, incorporating the Motivation for Physical Activity Measure - Revised (MPAM-R, was used to assess the motivations of 152 physical activity session participants in a highly deprived suburban neighbourhood. The MPAM-R data were analysed using t tests, analyses of variance to estimate age, body mass index, and activity mode differences and Pearson's correlation coefficient to address associations. Semi-structured interviews were also conducted with 33 local residents who did not participate in activity sessions and with 14 activity session leaders. All interviews were audio-taped, transcribed verbatim and analyzed using an inductive thematic approach. Results Participants reported cost, childcare, lack of time and low awareness as barriers to joining activity classes. The need for support, confidence and competence in order to take up activity was widely expressed, particularly among women. Once people are active, high levels of social interaction, interest and enjoyment are associated with improved levels of retention, with different types of physical activity scoring differently on these factors. Conclusions This study suggests that some factors such as cost, the fear of 'walking in alone', accessibility of facilities, and appropriate

  9. A programme for Euratom safeguards inspectors, used in the assay of high enriched (H.E.U.) and low enriched (L.E.U.) uranium fuel materials by active neutron interrogation

    International Nuclear Information System (INIS)

    Vocino, V.; Farese, N.; Maucq, T.; Nebuloni, M.

    1991-01-01

    The programme AECC (Active Euratom Coincidence Counters) has been developed at the Joint Research Center, Ispra by the Euratom Safeguards Directorate, Luxembourg and the Safety Technology Institute, Ispra for the acquisition, evaluation, management and storage of measurement data originating from active neutron interrogation of HEU and LEU fuel materials. The software accommodates the implementation of the NDA (Non Destructive Assay) procedures for the Active Well Coincidence Counters and Active Neutron Coincidence Counters deployed by the Euratom Safeguards Directorate, Luxembourg

  10. National energy efficiency programme

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper focusses on energy conservation and specifically on energy efficiency which includes efficiency in the production, delivery and utilisation of energy as part of the total energy system of the economy. A National Energy Efficiency Programme is being launched in the Eighth Plan that will take into account both macro level and policy and planning considerations as well as micro level responses for different category of users in the industry, agriculture, transport and domestic sectors. The need for such a National Energy Efficiency Programme after making an assessment of existing energy conservation activities in the country is discussed. The broad framework and contents of the National Energy Efficiency Programme have been outlined and the Eighth Plan targets for energy conservation and their break-up have been given. These targets, as per the Eighth Plan document are 5000 MW in electricity installed capacity and 6 million tonnes of petroleum products by the terminal year of the Eighth Plan. The issues that need to be examined for each sector for achieving the above targets for energy conservation in the Eighth Plan are discussed briefly. They are: (a) policy and planning, (b) implementation arrangements which include the institutional setup and selective legislation, (c) technological requirements, and (d) resource requirements which include human resources and financial resources. (author)

  11. The transport safety programme

    International Nuclear Information System (INIS)

    Selling, H.A.

    1994-01-01

    The transport safety programme is one of the smaller technical sub-programmes in the Radiation Safety Section of the Division of Nuclear Safety, in terms of both regular budget and professional staff allocations. The overall aim of the programme is to promote the safe movement of radioactive material worldwide. The specific objectives are the development, review and maintenance of the Regulations for the Safe Transport of Radioactive Material, Safety Series No 6, and its supporting documents Safety Series Nos 7, 37 and 80 and the assistance to Member States and International Organizations in the proper implementation of the Regulations. One of the important issues that emerged during an ongoing Review/Revision process is the transport of Low-Specific Activity (LSA) material and Surface Contaminated Objects (SCO). Many of the radioactive waste materials fall in one of these categories. The subject has gained substance because it is expected that in the next decade radioactive waste could become available in so far unprecedented quantities and volumes due to decontamination and decommissioning of nuclear facilities. (author)

  12. The programme of quality assurance relative to management and characterization of low activity wastes of Saclay nuclear study center

    International Nuclear Information System (INIS)

    Cordero, G.; Perotin, J.P.

    1988-05-01

    The technique for inspection and characterization of solid wastes with a low or very low α activity and medium β or γ activity allows to guarantee ANDRA, the collecting authority, an accurate, but not perfect, knowledge of the wastes and to limit the risk of non-compliance to technical prescription to an acceptable value. Choice of sampling technique limits the number of analysis and automation limits cost and personnal risks [fr

  13. National programme: Finland

    International Nuclear Information System (INIS)

    Forsten, J.

    1986-01-01

    Finland's programmes in the field of reactor pressure components are presented in this paper. The following information on each of these programmes is given: the brief description of the programme; the programme's schedule and duration; the name of the project manager

  14. Customers' perspectives on the impact of the Pathways to Work condition management programme on their health, well-being and vocational activity.

    Science.gov (United States)

    Secker, Jenny; Pittam, Gail; Ford, Fiona

    2012-11-01

    Pathways to Work is a UK initiative aimed at supporting customers on incapacity benefits to return to work. This qualitative study complements previous evaluations of Pathways to Work by exploring customers' perceptions of the impact of the Condition Management Programme (CMP) offered to claimants with long-term health conditions. 39 customers took part in focus groups held at the seven sites where Pathways was originally piloted. The main focus of the discussions was on perceptions of the ways in which participation had impacted on health, well-being and return to work. The discussions were audio-recorded and fully transcribed for analysis using a text analysis framework to enable the development and refinement of categories and overarching patterns in the data. Perceived impacts on health and well-being included a more positive outlook, social contact, changed perceptions of conditions and improvements in health. Some customers also reported an increase in their vocational activity and others felt ready to embark on new activities. Factors associated with positive outcomes included the extent and quality of contact with CMP staff and practical advice about condition management. Factors impeding positive employment outcomes related mainly to obstacles to returning to work. The results indicated that CMP can assist customers to learn about and manage their health conditions and increase their vocational activity, and that CMP therefore provides a promising means of enabling people with long-term health conditions to regain a fulfilling, productive life.

  15. MDEP Conference on New Reactor Design Activities - Multinational Design Evaluation Programme (MDEP) Conference Proceedings, Paris, France, 10-11 September 2009

    International Nuclear Information System (INIS)

    2010-01-01

    The MDEP is a unique ten-nation initiative being undertaken by national regulatory authorities from Canada, China, Finland, France, Japan, Republic of Korea, the Russian Federation, South Africa, the United Kingdom, and the United States with the purposes of co-operating on safety design reviews of new reactors and identifying opportunities to harmonise and converge on safety licensing review practices and requirements. The OECD Nuclear Energy Agency has been chosen to provide the technical secretariat support. The International Atomic Energy Agency participates in many of the MDEP activities. Started in 2007 with co-operation on various pilot project issues, the MDEP's expected outcomes are: (1) improved effectiveness and efficiency of regulatory safety design reviews, (2) increased quality of safety assessments, and (3) and identified areas for the convergence of regulatory requirements and practices. Making each regulator stronger in its ability to make sovereign safety decisions is a key objective that cuts across all MDEP activities. In 2008, the top regulators from each national authority met as the MDEP Policy Group and adopted the present structure and programme of work for the MDEP, including the pursuit of co-operation on specific safety design reviews and pursuing closer co-ordination on harmonisation and convergence issues such as digital instrumentation and control, mechanical codes and standards, and vendor inspections. The MDEP is currently a long-term programme that focuses in near term and interim results to share within MDEP and with other stakeholders. With effective communications in mind, the MDEP Policy Group directed the NEA to co-ordinate the Conference on New Reactor Design Activities with the purpose of communicating to a wide spectrum of stakeholders worldwide as to the program of work and accomplishments of the MDEP, and soliciting feedback and input from these stakeholders regarding recommendations on how to co-operate more efficiently

  16. Activity determination for neutron dosimetry in the vigilance programme for the pressure vessel in Atucha I nuclear power plant

    International Nuclear Information System (INIS)

    Furnari, J.C.; Cohen, I.M.; Ciriani, D.F.; Helzel Garcia, J.

    1993-01-01

    The methodologies for the activity determination of Co-60, Nb-93m and Nb-94 in flux monitors are presented. This was done in order to evaluate dose and damage caused by radiation received by pressure vessel materials of the Atucha I nuclear power plant for its surveillance program. (author)

  17. Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing

    DEFF Research Database (Denmark)

    Bousquet, J; Farrell, J; Crooks, G

    2016-01-01

    Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS ...

  18. Implementation of a metrology programme to provide traceability for radionuclides activity measurements in the CNEN Radiopharmaceuticals Producers Centers

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Erica A.L. de; Braghirolli, Ana M.S.; Tauhata, Luiz; Gomes, Regio S.; Silva, Carlos J., E-mail: erica@ien.gov.br [Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Delgado, Jose U.; Oliveira, Antonio E.; Iwahara, Akira, E-mail: ealima@ird.gov.br [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2013-07-01

    The commercialization and use of radiopharmaceuticals in Brazil are regulated by Agencia Nacional de Vigilancia Sanitaria (ANVISA) which require Good Manufacturing Practices (GMP) certification for Radiopharmaceuticals Producer Centers. Quality Assurance Program should implement the GMP standards to ensure radiopharmaceuticals have requirements quality to proving its efficiency. Several aspects should be controlled within the Quality Assurance Programs, and one of them is the traceability of the Radionuclides Activity Measurement in radiopharmaceuticals doses. The quality assurance of activity measurements is fundamental to maintain both the efficiency of the nuclear medicine procedures and patient and exposed occupationally individuals safety. The radiation doses received by patients, during the nuclear medicine procedures, is estimated according to administered radiopharmaceuticals quantity. Therefore it is very important either the activity measurements performed in radiopharmaceuticals producer centers (RPC) as the measurements performed in nuclear medicine services are traceable to national standards. This paper aims to present an implementation program to provide traceability to radionuclides activity measurements performed in the dose calibrators(well type ionization chambers) used in Radiopharmaceuticals Producer Center placed in different states in Brazil. The proposed program is based on the principles of GM Pand ISO 17025 standards. According to dose calibrator performance, the RPC will be able to provide consistent, safe and effective radioactivity measurement to the nuclear medicine services. (author)

  19. Co-ordination and methodological guidance of information activities in the Czechoslovak nuclear programme in building the branch information system

    International Nuclear Information System (INIS)

    Nejezchleb, V.

    1982-01-01

    The work of the control unit is described which secures the optimal operation of the system, its internal functions and its linkage with other systems. The aim of coordination and methodological activity is to strengthen working and organizational links within the framework of the construction and operation of sector information systems, the establishment of cooperation relations and the elimination of duplicity. (M.D.)

  20. The youth camp programmes which are carried out by Ministry of Youth and Sports as a leisure time activity

    Directory of Open Access Journals (Sweden)

    Melike ESENTAS

    2016-06-01

    Full Text Available Aim: In this survey it is aimed to analyse, interpret and to give proposals when necessary to the ideas of women and men participants of youth camps organised as spare time activity aged 13-15 and 16-17 about sea camp program and leader behaviours. Material and Methods: The participants that are in this research are 205 women and 347 men and totally 552 students who are in Çeşme Paşalimanı sea camp in three different terms. A personal data form and a questionairre form is prepared in order to establish the demographic features and profiles of participants of Free of Charge Sea Camp. The questionnairre involves yes-no questions, multiple choice and open-ended questions about the camp program and the camp leader. Once the survey was completed, all the personal data forms and questionairres has been checked to gain information, data has been coded to be comforable to code instruction. The obtained data using descriptive statistics methods, tables have been created, it is interpreted by looking at the percentage and frequency distribution. Results: The youth camps ,which are spare time activities, effects the participants in a positive way. The participants emphasized that when the camp finished they had good friendships, they gained self-confidence and they determined that they had positive transfers about team working and used these workings in their lifesytles. İn accordance age groups the cleaning problem is determined in high rate that is very interesting findings. Thus, the negative features of camp programs need to be healed. Conclusion: At the end of the survey It is concluded that while planning the activities women and men participation should be done equally and considering the age factor the activities which will meet the needs of all age groups should be involved in the program, and moreover increasing the number of the sea activities are advised.

  1. Factors affecting 210Po and 210Pb activity concentrations in mussels and implications for environmental bio-monitoring programmes

    International Nuclear Information System (INIS)

    Carvalho, Fernando P.; Oliveira, Joao M.; Alberto, G.

    2011-01-01

    The activity of 210 Po and 210 Pb was determined in mussels of the same size (3.5-4.0 cm shell length) sampled monthly over a 17-month period at the Atlantic coast of Portugal. Average radionuclide concentration values in mussels were 759 ± 277 Bq kg -1 for 210 Po (range 460-1470 Bq kg -1 dry weight), and 45 ± 19 Bq kg -1 for 210 Pb (range 23-96 Bq kg -1 dry weight). Environmental parameters and mussel biometric parameters were monitored during the same period. Although there was no seasonal variation of radionuclide concentrations in sea water during the study period, the concentration of radionuclide activity in mussels varied seasonally displaying peaks of high concentrations in winter and low concentrations in summer. Analysis of radionuclide data in relation to the physiological Condition Index of mussels revealed that 210 Po and 210 Pb activities in the mussel (average activity per individual) remained nearly constant during the investigation period, while mussel body weight fluctuated due to fat storage/expenditure in the soft tissues. Similar variation of radionuclide concentrations was observed in mussels transplanted from the sea coast into the Tejo Estuary. However, under estuarine environmental conditions and with higher food availability throughout the year, transplanted mussel Condition Index was higher than in coastal mussels and average radionuclide concentrations were 210 ± 75 Bq kg -1 (dry weight) for 210 Po and 10 ± 4 Bq kg -1 (dry weight) for 210 Pb, therefore lower than in coastal mussels with similar shell length. It is concluded that the apparent seasonal fluctuation and inter-site difference of radionuclide concentrations were mostly caused by mussel body weight fluctuation and not by radionuclide body burden fluctuation. This interpretation can be extended to the apparent seasonal fluctuation in concentrations of lipophilic and lipophobic contaminants in mussels, and provides an explanation for occasional high concentrations of 210 Po

  2. Effect on motivation, perceived competence, and activation after participation in the ''Ready to Act'' programme for people with screen-detected dysglycaemia: a 1-year randomised controlled trial, Addition-DK.

    Science.gov (United States)

    Maindal, Helle Terkildsen; Sandbæk, Annelli; Kirkevold, Marit; Lauritzen, Torsten

    2011-05-01

    To investigate the reach of the ''Ready to Act'' programme and the 1-year effects on psychological determinants of healthy behaviour: motivation, perceived competence, and activation level. A total of 509 adults with dysglycaemia were recruited from general practioners (GPs) in the intensive arm of the Danish Anglo-Danish-Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION) study, a type 2 diabetes screening programme. The participants were randomised to the ''Ready to Act'' programme added on top of GP care (n = 322) or to GP care (n = 187). The core components of the programme were motivation, action experience, informed decision-making, and social involvement conducted in two one-to-one sessions and eight group-meetings (18 hours). The reach of the programme was measured by the proportion of people who signed up. Outcomes were changes in treatment motivation (Treatment Self-Regulation Questionnaire, TSRQ), perceived competence (Perceived Competence Scale, PCS), and activation in chronic care (Patient Activation Measure, PAM). Effect size was the difference between 1-year changes in the randomisation groups analysed by intention-to-treat. A total of 142 (44%) of 322 signed up and 123 (87%) of these completed. At 1 year, the difference in autonomous motivation for behavioural treatment (TSRQ) between the randomisation groups was 1.0 (95% CI 0.1 to 2.0), and the difference in perceived competence changes in healthy diet (PCS-d) was 1.5 (95% CI 0.2 to 2.7). No differences were observed for activation (PAM) between the groups. Subgroup analysis revealed men to benefit more from the intervention than women. The programme is a promising health-promoting component in prevention and care for people with screen-detected dysglycaemia, as it attracted four of 10 people and had effects on motivation and perceived competence.

  3. Impact of a school-based intervention on nutritional education and physical activity in primary public schools in Chile (KIND programme study protocol: cluster randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Nelly Bustos

    2016-12-01

    Full Text Available Abstract Background Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes have been implemented, however the effectiveness of these needs to be evaluated to identify and prioritize strategies to curve this trend. Methods Cluster randomized controlled trial. Twelve primary public schools chosen at random over three regions of the country will take part in this study. The sample size consisted of a total of 1,655 children. For each region one school will be selected for each of the three nutritional intervention modes and one school will be selected as the control group. The intervention modes consist of the following: Healthy Kiosk and nutritional education (KSEAN; Optimized physical activity (AFSO; Healthy Kiosk and nutritional education (KSEAN + optimized physical activity (AFSO; Control group. The effectiveness of each intervention will be evaluated by determining the nutritional condition of each child by measuring percentage of body fat, BMI and the z-score of the BMI. This study will also identify the eating behaviours, nutritional knowledge and fitness of each child, along with the effective time of moderate activity during physical education classes. Discussion A protocol to evaluate the effectiveness of a school based intervention to control and/or reduce the rates of childhood obesity for children between 6 and 10 years of age was developed. The protocol was developed in line with the Declaration of Helsinski, the Nüremberg Code and the University of Chile Guidelines for ethical committees, and was approved by the INTA, Universidad de Chile ethical committee on Wednesday 12 March 2014. There is consensus among researchers and health and education personnel that schools are a favourable environment for actions to prevent and/or control childhood obesity. However a lack of evidence on the effectiveness of interventions to date has led some to question the wisdom of

  4. Impact of a school-based intervention on nutritional education and physical activity in primary public schools in Chile (KIND) programme study protocol: cluster randomised controlled trial.

    Science.gov (United States)

    Bustos, Nelly; Olivares, Sonia; Leyton, Bárbara; Cano, Marcelo; Albala, Cecilia

    2016-12-03

    Chile has suffered a fast increase in childhood obesity in the last 10 years. As a result, several school programmes have been implemented, however the effectiveness of these needs to be evaluated to identify and prioritize strategies to curve this trend. Cluster randomized controlled trial. Twelve primary public schools chosen at random over three regions of the country will take part in this study. The sample size consisted of a total of 1,655 children. For each region one school will be selected for each of the three nutritional intervention modes and one school will be selected as the control group. The intervention modes consist of the following: Healthy Kiosk and nutritional education (KSEAN); Optimized physical activity (AFSO); Healthy Kiosk and nutritional education (KSEAN) + optimized physical activity (AFSO); Control group. The effectiveness of each intervention will be evaluated by determining the nutritional condition of each child by measuring percentage of body fat, BMI and the z-score of the BMI. This study will also identify the eating behaviours, nutritional knowledge and fitness of each child, along with the effective time of moderate activity during physical education classes. A protocol to evaluate the effectiveness of a school based intervention to control and/or reduce the rates of childhood obesity for children between 6 and 10 years of age was developed. The protocol was developed in line with the Declaration of Helsinski, the Nüremberg Code and the University of Chile Guidelines for ethical committees, and was approved by the INTA, Universidad de Chile ethical committee on Wednesday 12 March 2014. There is consensus among researchers and health and education personnel that schools are a favourable environment for actions to prevent and/or control childhood obesity. However a lack of evidence on the effectiveness of interventions to date has led some to question the wisdom of allocating resources to programmes. This is the first study

  5. Study design and protocol for a mixed methods evaluation of an intervention to reduce and break up sitting time in primary school classrooms in the UK: The CLASS PAL (Physically Active Learning) Programme

    OpenAIRE

    Routen, Ash C; Biddle, Stuart J H; Bodicoat, Danielle H; Cale, Lorraine; Clemes, Stacy; Edwardson, Charlotte L; Glazebrook, Cris; Harrington, Deirdre M; Khunti, Kamlesh; Pearson, Natalie; Salmon, Jo; Sherar, Lauren B

    2017-01-01

    Introduction Children engage in a high volume of sitting in school, particularly in the classroom. A number of strategies, such as physically active lessons (termed movement integration (MI)), have been developed to integrate physical activity into this learning environment; however, no single approach is likely to meet the needs of all pupils and teachers. This protocol outlines an implementation study of a primary school-based MI intervention: CLASS PAL (Physically Active Learning) programm...

  6. The influence of a tilt training programme on the renin-angiotensin-aldosterone system activity in patients with vasovagal syncope.

    Science.gov (United States)

    Gajek, Jacek; Zyśko, Dorota; Krzemińska, Sylwia; Mazurek, Walentyna

    2009-08-01

    We assessed the influence of short-term and long-term tilt training on the activity of the renin-angiotensin-aldosterone system (RAAS) in vasovagal patients. Thirty-nine patients (28 F, 11 M) aged 39.7 +/- 11.2 years with a history of vasovagal syncope and a positive head-up tilt test (HUT) were studied. Blood samples for plasma renin activity (PRA) and aldosterone (ALDO) concentration were drawn at the baseline, immediately after HUT and 10 min after HUT, during the diagnostic, the negative short-term (2-5 days) follow-up HUT and long-term (1-3 months) follow-up HUT. Tilt training was started after diagnostic HUT. In diagnostic HUT, PRA increased significantly immediately after HUT comparing to the baseline, during recovery the values did not change. ALDO concentration increased after HUT comparing to baseline and further increased during recovery. After short-term tilt training, PRA and ALDO concentrations did not significantly change compared to their corresponding values in diagnostic HUT. After long-term tilt training, PRA did not significantly change compared to the values in the diagnostic and short-term follow-up HUT. ALDO concentration also did not change significantly at the baseline and immediately after HUT, and 10 min after HUT ALDO concentration was significantly lower than after diagnostic HUT. Tilt training changes the response of RAAS to the prolonged orthostasis in vasovagal patients. The coupling between PRA and ALDO after diagnostic HUT has been found to be altered and the physiological relationship was restored after long-term tilt training. The beneficial effect of tilt training depends partially on changed RAAS activation.

  7. Seismic safety programme at NPP Paks. Propositions for coordinated international activity in seismic safety of the WWER-440 V-213

    International Nuclear Information System (INIS)

    Katona, T.

    1995-01-01

    This paper presents the Paks NPP seismic safety program, highlighting the specifics of the WWER-440/213 type in operation, and the results of work obtained so far. It covers the following scope: establishment of the seismic safety program (original seismic design, current requirements, principles and structure of the seismic safety program); implementation of the seismic safety program (assessing the seismic hazard of the site, development of the new concept of seismic safety for the NPP, assessing the seismic resistance of the building and the technology); realization of the seismic safety of higher level (technical solutions, drawings, realization); ideas and propositions for coordinated international activity

  8. The challenge and impact of engaging hard-to-reach populations in regular physical activity and health behaviours: an examination of an English Premier League 'Football in the Community' men's health programme.

    Science.gov (United States)

    Curran, K; Drust, B; Murphy, R; Pringle, A; Richardson, D

    2016-06-01

    To investigate the challenges that men from hard-to-reach (HTR) populations encounter when attempting to commit to regular participation in physical activity and health behaviours, and to explore the psychological and social effects of participation in a twelve week football-led health improvement intervention. A twelve week football specific physical activity intervention targeting men from HTR populations was delivered by Everton Football Clubs' Football in the Community (FitC) scheme as part of a national programme of men's health delivered in/by English Premier League (EPL) football clubs. Men living in homeless shelters and/or recovering from substance misuse were recruited over a period of three months. The programme consisted of a two hour football session, twice weekly, alongside the dissemination of healthy living messages. Football sessions were conducted by a qualified FitC coach. This research was conducted during a twelve week period of immersed practitioner-research. Ethnographic and observational methodologies were adopted. Psychosocial issues were discussed with participants through informal client-researcher interactions and data were logged via field notes. Records of attendance were logged. Participants who failed to attend a session were contacted and their reason(s) for non-attendance were recorded. Data were analysed using deductive and inductive reasoning. Despite the apparent ambition of the participants to regularly participate in the FitC programme, adherence to the programme was poor. Economic, environmental and social barriers to engagement in the programme were apparent. Engagement in the programme resulted in positive psychosocial developments; the development of structure, social interaction and social capital. Community based football-led health improvement programmes endorsed by professional football clubs appear well positioned to connect with, and attract, men from HTR populations. The evidence suggests that such programmes can

  9. Evaluation of an intervention programme addressing ability to perform activities of daily living among persons with chronic conditions: study protocol for a feasibility trial (ABLE)

    DEFF Research Database (Denmark)

    Guidetti, Susanne; Nielsen, Kristina Tomra; von Bülow, Cecilie

    2018-01-01

    version of the ABLE intervention programme was developed. Methods and analysis This feasibility study examine the perceived value and acceptability of the ABLE programme by evaluating the fidelity, reach, dose and potential outcomes using a pretest and post-test design involving 30 persons living...

  10. DK crush (double-kissing and double-crush) technique for treatment of true coronary bifurcation lesions: illustration and comparison with classic crush.

    Science.gov (United States)

    Chen, Shaoliang; Zhang, Junjie; Ye, Fei; Zhu, Zhongsheng; Lin, Song; Shan, Shoujie; Kwan, Tak W

    2007-04-01

    Classic crush has a lower success rate compared to final kissing balloon inflation (FKBI). We previously reported the double-kissing (DK) crush technique that involves double-kissing along with double-crushing for the treatment of true bifurcation coronary lesions in 2005. This is a consecutive, nonrandomized, open-label study. Eighty-eight consecutive patients with single, true coronary bifurcation lesions according to Lefevre Classification2 and side branch diameter >2.0 mm were enrolled. The first 44 patients (from October 2004 to January 2005) were assigned to the classic crush treatment arm and the next 44 patients (from February 2005 to June 2005) were assigned to the DK crush technique arm, respectively. Data within 30 days were analyzed. Patients in the DK crush group, compared to those in classic crush group, were characterized by longer lesion length in the side branch (13.5 +/- 3.4 mm vs 7.8 +/- 3.1 mm; p DK crush group, as well as longer lesion length in the main vessel (24.3 +/- 8.6 mm vs 21.1 +/- 7.3 mm), though without significant differences (p >0.05). Subacute stent thrombosis was detected in 2 patients with failure of FKBI in the classic crush group (4.3%). In addition, patients in the classic crush group were characterized by a smaller minimum lumen diameter (MLD) at the side branch ostium (2.74 +/- 0.12 mm vs 3.01 +/- 0.13 mm; p DK crush has the potential to improve the clinical outcome in patients with coronary bifurcation lesions. Further randomized, prospective, multicenter studies are required to confirm these differences between the classic crush and DK crush techniques.

  11. Normosmic idiopathic hypogonadotropic hypogonadism due to a novel homozygous nonsense c.C969A (p.Y323X) mutation in the KISS1R gene in three unrelated families.

    Science.gov (United States)

    Demirbilek, Huseyin; Ozbek, M Nuri; Demir, Korcan; Kotan, L Damla; Cesur, Yasar; Dogan, Murat; Temiz, Fatih; Mengen, Eda; Gurbuz, Fatih; Yuksel, Bilgin; Topaloglu, A Kemal

    2015-03-01

    The spectrum of genetic alterations in cases of hypogonadotropic hypogonadism continue to expand. However, KISS1R mutations remain rare. The aim of this study was to understand the molecular basis of normosmic idiopathic hypogonadotropic hypogonadism. Clinical characteristics, hormonal studies and genetic analyses of seven cases with idiopathic normosmic hypogonadotropic hypogonadism (nIHH) from three unrelated consanguineous families are presented. One male presented with absence of pubertal onset and required surgery for severe penoscrotal hypospadias and cryptorchidism, while other two males had absence of pubertal onset. Two of four female cases required replacement therapy for pubertal onset and maintenance, whereas the other two had spontaneous pubertal onset but incomplete maturation. In sequence analysis, we identified a novel homozygous nonsense (p.Y323X) mutation (c.C969A) in the last exon of the KISS1R gene in all clinically affected cases. We identified a homozygous nonsense mutation in the KISS1R gene in three unrelated families with nIHH, which enabled us to observe the phenotypic consequences of this rare condition. Escape from nonsense-mediated decay, and thus production of abnormal proteins, may account for the variable severity of the phenotype. Although KISS1R mutations are extremely rare and can cause a heterogeneous phenotype, analysis of the KISS1R gene should be a part of genetic analysis of patients with nIHH, to allow better understanding of phenotype-genotype relationship of KISS1R mutations and the underlying genetic basis of patients with nIHH. © 2014 John Wiley & Sons Ltd.

  12. Geological Changes of the Americas and their Influence on the Diversification of the Neotropical Kissing Bugs (Hemiptera: Reduviidae: Triatominae).

    Science.gov (United States)

    Justi, Silvia A; Galvão, Cleber; Schrago, Carlos G

    2016-04-01

    The family Reduviidae (Hemiptera: Heteroptera), or assassin bugs, is among the most diverse families of the true bugs, with more than 6,000 species. The subfamily Triatominae (kissing bugs) is noteworthy not simply because it is the only subfamily of the Reduviidae whose members feed on vertebrate blood but particularly because all 147 known members of the subfamily are potential Chagas disease vectors. Due to the epidemiological relevance of these species and the lack of an efficient treatment and vaccine for Chagas disease, it is more common to find evolutionary studies focusing on the most relevant vectors than it is to find studies aiming to understand the evolution of the group as a whole. We present the first comprehensive phylogenetic study aiming to understand the events that led to the diversification of the Triatominae. We gathered the most diverse samples of Reduviidae and Triatominae (a total of 229 Reduviidae samples, including 70 Triatominae species) and reconstructed a robust dated phylogeny with several fossil (Reduviidae and Triatominae) calibrations. Based on this information, the possible role of geological events in several of the major cladogenetic events within Triatominae was tested for the first time. We were able to not only correlate the geological changes in the Neotropics with Triatominae evolution but also add to an old discussion: Triatominae monophyly vs. paraphyly. We found that most of the diversification events observed within the Rhodniini and Triatomini tribes are closely linked to the climatic and geological changes caused by the Andean uplift in South America and that variations in sea levels in North America also played a role in the diversification of the species of Triatoma in that region.

  13. The acute changes of fractional flow reserve in DK (double kissing), crush, and 1-stent technique for true bifurcation lesions.

    Science.gov (United States)

    Ye, Fei; Zhang, Jun-Jie; Tian, Nai-Liang; Lin, Song; Liu, Zhi-Zhong; Kan, Jing; Xu, Hai-Mei; Zhu, Zhongsheng; Chen, Shao-Liang

    2010-08-01

    While many studies confirmed the importance of fractional flow reserve (FFR) in guiding complex percutaneous coronary interventions (PCI), data regarding the significance of FFR for bifurcation lesions are still lacking. Between October 2008 and October 2009, 51 patients with true bifurcation lesions were consecutively enrolled and randomized into double kissing (DK) crush (n = 25), and provisional 1-stent (n = 26) groups. FFR measurements at baseline and hyperemia were measured at pre-PCI, post-PCI, and at 8-month follow-up. Clinical follow-ups were available in 100% of patients while only 33% of patients underwent angiographic follow-up. Baseline clinical and angiographic characteristics were matched between the 2 groups. Pre-PCI FFR of the main branch (MB) in the DK group was 0.76 +/- 0.15, which was significantly lower than in the provisional 1-stent group (0.83 +/- 0.10, P = 0.029). This difference disappeared after the PCI procedure (0.92 +/- 0.04 vs. 0.92 +/- 0.05, P = 0.58). There were no significant differences in terms of baseline, angiographic, procedural indexes, and FFR of side branch (SB) between the 2 treatment arms. However, immediately after PCI, the patient with DK crush had higher FFR in the SB as compared to the provisional 1-stent group (0.94 +/- 0.03 vs. 0.90 +/- 0.08, P = 0.028, respectively) and also they had lower diameter stenosis (8.59 +/- 6.41% vs. 15.62 +/- 11.69%, P = 0.015, respectively). In the acute phase, immediately after PCI for bifurcation lesion, DK crush stenting was associated with higher FFR and lower residual diameter stenosis in the SB, as compared with the provisional 1-stent group.

  14. Effects of a partially supervised conditioning programme in cystic fibrosis: an international multi-centre randomised controlled trial (ACTIVATE-CF): study protocol.

    Science.gov (United States)

    Hebestreit, Helge; Lands, Larry C; Alarie, Nancy; Schaeff, Jonathan; Karila, Chantal; Orenstein, David M; Urquhart, Don S; Hulzebos, Erik H J; Stein, Lothar; Schindler, Christian; Kriemler, Susi; Radtke, Thomas

    2018-02-08

    Physical activity (PA) and exercise have become an accepted and valued component of cystic fibrosis (CF) care. Regular PA and exercise can positively impact pulmonary function, improve physical fitness, and enhance health-related quality of life (HRQoL). However, motivating people to be more active is challenging. Supervised exercise programs are expensive and labour intensive, and adherence falls off significantly once supervision ends. Unsupervised or partially supervised programs are less costly and more flexible, but compliance can be more problematic. The primary objective of this study is to evaluate the effects of a partially supervised exercise intervention along with regular motivation on forced expiratory volume in 1 s (FEV 1 ) at 6 months in a large international group of CF patients. Secondary endpoints include patient reported HRQoL, as well as levels of anxiety and depression, and control of blood sugar. It is planned that a total of 292 patients with CF 12 years and older with a FEV 1  ≥ 35% predicted shall be randomised. Following baseline assessments (2 visits) patients are randomised into an intervention and a control group. Thereafter, they will be seen every 3 months for assessments in their centre for one year (4 follow-up visits). Along with individual counselling to increase vigorous PA by at least 3 h per week on each clinic visit, the intervention group documents daily PA and inactivity time and receives a step counter to record their progress within a web-based diary. They also receive monthly phone calls from the study staff during the first 6 months of the study. After 6 months, they continue with the step counter and web-based programme for a further 6 months. The control group receives standard care and keeps their PA level constant during the study period. Thereafter, they receive the intervention as well. This is the first large, international multi-centre study to investigate the effects of a PA intervention in CF with

  15. Recombination in the 5' leader of murine leukemia virus is accurate and influenced by sequence identity with a strong bias toward the kissing-loop dimerization region

    DEFF Research Database (Denmark)

    Mikkelsen, J G; Lund, Anders Henrik; Duch, M

    1998-01-01

    during minus-strand DNA synthesis occurred within defined areas of the genome and did not lead to misincorporations at the crossover site. The nonrandom distribution of recombination sites did not reflect a bias for specific sites due to selection at the level of marker gene expression. We address...... whether template switching is affected by the length of sequence identity, by palindromic sequences, and/or by putative stem-loop structures. Sixteen of 24 sites of recombination colocalized with the kissing-loop dimerization region, and we propose that RNA-RNA interactions between palindromic sequences...

  16. Work in the coordinated programme on neutron activation analysis of pollutants in human hair, using research reactors

    International Nuclear Information System (INIS)

    Lanzel, E.

    1978-11-01

    Scalp hair samples from the population of four different regions in Austria (Vienna, Burgenland, East Tyrol and Vorarlberg) were analyzed by instrumental neutron activation analysis for As, Sb, Cd, Hg, Br and Zn. For each representative group, the range of concentrations, the geometric mean with the antilog of the logarithmic standard deviation and the median were determined. The distribution histogrammes were also given for the frequency as a function of the concentration. The means of concentrations were in the normal range. Thus, no contamination for the population in total could be suspected. A different picture was observed for the Burgenland group. There was a tail of high concentrations of As and Sb superposed upon the usual log-normal distribution. This tail was due to contamination from mines for a part of the Burgenland group. Increased levels of Cd and Zn were also found for this subgroup. This study demonstrated the validity of analysis of scalp hair for the primary monitoring of trace element contamination of man. For this purpose hair has definite advantages over other human specimen available in vivo such as blood or urine

  17. An After-School, high-intensity, interval physical activity programme improves health-related fitness in children

    Directory of Open Access Journals (Sweden)

    Sergio Reloba Martínez

    Full Text Available Abstract Health problems related to a low level of physical activity (PA in children and adolescents have prompted research into extracurricular PA programs. This study was designed to determine the effects of two different levels of PA on the health-related fitness of school children. Ninety-four girls and boys (7-9 years were randomly assigned to a control group (CG or intervention group (IG. Over a 12 week study period, children in the CG participated in a similar PA program to that of a standard school physical education program while those in the IG completed a high intensity interval training (HIIT program. Both programs involved two 40 minute extracurricular sessions per week. Our findings indicate that the HIIT intervention improved motor capacity (speed/agility, Vpeak, VO2 max and excess post-exercise oxygen consumption (EPOC (p < 0.05 along with the musculoskeletal capacity of the lower trunk (mean propulsive velocity and standing long jump, p < 0.05. The PA program had no effect on anthropometric variables or hand-grip strength. The data indicate that a 12 week strength training program using workloads adapted to children may significantly improve several markers of health and physical fitness compared to a standard school PA program.

  18. Smart teens don't have sex (or kiss much either).

    Science.gov (United States)

    Halpern, C T; Joyner, K; Udry, J R; Suchindran, C

    2000-03-01

    To examine the relationship between an intelligence measure and a wide spectrum of partnered sexual activity ranging from holding hands to sexual intercourse among adolescents. Analyses are based on two separate samples of adolescents. The core sample of the National Longitudinal Study of Adolescent Health (Add Health) includes approximately 12,000 adolescents enrolled in the 7th to 12th grades. The Biosocial Factors in Adolescent Development projects followed approximately 100 white males and 200 black and white females over 3- and 2-year periods, respectively. Both studies used the Peabody Picture Vocabulary Test (PPVT) as an intelligence measure, and confidential self-reports of sexual activity. Logistic regression models were used to examine the relationship between PPVT scores and coital status in Add Health data; proportional hazard models were used to examine the timing of initiation of noncoital and coital activities as a function of PPVT scores in the Biosocial Factors sample. Controlling for age, physical maturity, and mother's education, a significant curvilinear relationship between intelligence and coital status was demonstrated; adolescents at the upper and lower ends of the intelligence distribution were less likely to have sex. Higher intelligence was also associated with postponement of the initiation of the full range of partnered sexual activities. An expanded model incorporating a variety of control and mediator variables was tested to identify mechanisms by which the relationship operates. Higher intelligence operates as a protective factor against early sexual activity during adolescence, and lower intelligence, to a point, is a risk factor. More systematic investigation of the implications of individual differences in cognitive abilities for sexual activities and of the processes that underlie those activities is warranted.

  19. Californium loan programme

    International Nuclear Information System (INIS)

    1974-01-01

    The offer of the United States to loan Californium-252 sources to the IAEA was made by Dr. Glenn T. Seaborg, then chairman of the USAEC, in his opening statement at the 15th. General Conference of the IAEA held in Vienna in 1971. The purpose of this loan was to make neutron emitting sources available to universities in the Member States for use in educational programmes. The sources, in the form of small needles designed for medical use in radiation therapy, were judged highly suitable for didactic applications due to their small size, limited activity and well documented radiological parameters. Subsequently, in May 1973, the Director General announced the availability of the Californium sources to the Member States. To date, numerous sources have been loaned to universities in Czechoslovakia, Costa Rica, the Federal Republic of Germany, Ghana, India, Iran, Israel, Japan, South Africa, Switzerland, the United Kingdom and Uruguay; additional applications for loans are being processed. It is anticipated that the loan programme will be terminated in 1975 once all the available sources have been distributed. n order to provide guidance for the Member States on the safe exploitation of these sources, a prototype use and storage facility was designed by IAEA staff of the Dosimetry Section of the Division of Life Sciences, and constructed at the IAEA laboratory in Seibersdorf, Austria. Figures 2-5 illustrate some of the details of this container, which is being given to the Ghana Nuclear Centre in support of a training programme for students at the university in Accra. Further advice to users of these sources will be provided by the publication of an instructional syllabus, a laboratory manual for experiments and the safety precautions inherent in the proper handling of neutron emitting radionuclides, authored by Professors Erich J. Hall and Harald H. Rossi of Columbia University. The syllabus and manual will be published as part of the IAEA Technical Series in September

  20. HADES RV Programme with HARPS-N at TNG. VI. GJ 3942 b behind dominant activity signals

    Science.gov (United States)

    Perger, M.; Ribas, I.; Damasso, M.; Morales, J. C.; Affer, L.; Suárez Mascareño, A.; Micela, G.; Maldonado, J.; González Hernández, J. I.; Rebolo, R.; Scandariato, G.; Leto, G.; Zanmar Sanchez, R.; Benatti, S.; Bignamini, A.; Borsa, F.; Carbognani, A.; Claudi, R.; Desidera, S.; Esposito, M.; Lafarga, M.; Martinez Fiorenzano, A. F.; Herrero, E.; Molinari, E.; Nascimbeni, V.; Pagano, I.; Pedani, M.; Poretti, E.; Rainer, M.; Rosich, A.; Sozzetti, A.; Toledo-Padrón, B.

    2017-12-01

    Context. Short- to mid-term magnetic phenomena on the stellar surface of M-type stars can resemble the effects of planets in radial velocity data, and may also hide them. Aims: We analyze 145 spectroscopic HARPS-N observations of GJ 3942 taken over the past five years and additional photometry in order to disentangle stellar activity effects from genuine Doppler signals as a result of the orbital motion of the star around the common barycenter with its planet. Methods: To achieve this, we use the common methods of pre-whitening, and treat the correlated red noise by a first-order moving average term and by Gaussian-process regression following an MCMC analysis. Results: We identify the rotational period of the star at 16.3 days and discover a new super-Earth, GJ 3942 b, with an orbital period of 6.9 days and a minimum mass of 7.1 M⊕. An additional signal in the periodogram of the residuals is present, but at this point we cannot claim with sufficient significance that it is related to a second planet. If confirmed, this planet candidate would have a minimum mass of 6.3 M⊕ and a period of 10.4 days, which might indicate a 3:2 mean-motion resonance with the inner planet. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roque de los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); photometric observations from the APACHE array located at the Astronomical Observatory of the Aosta Valley; photometric observations made with the robotic APT2 (within the EXORAP program) located at Serra La Nave on Mt. Etna.Table 9 is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/608/A63

  1. The new active driving safety system ESP (Electronic Stability Program) developed by Mercedes Benz; Das neue aktive Fahrsicherheitssystem ESP (Elektronisches-Stabilitaets-Programm) von Mercedes-Benz

    Energy Technology Data Exchange (ETDEWEB)

    Paul, J. [Mercedes-Benz AG, Stuttgart (Germany); Klinkner, W. [Mercedes-Benz AG, Stuttgart (Germany); Mueller, A. [Mercedes-Benz AG, Stuttgart (Germany)

    1995-12-31

    The new electronic stability program (ESP) offered by Mercedes-Benz as a world novelty in March 1995 is the consequent further development of the anti-lock braking system and the anti-slip control. An improved assessment of the handling properties by a steering wheel sensor, a yaw velocity sensor, a brake pressure sensor and a hydraulic system that brakes each wheel individually and is controlled by a complex logic allow the supervision and the active control of the cross-dynamic handling properties up to limiting ranges. The handling of the vehicle in critical situations (e.g. strong oversteering or understeering) has been considerably improved. (orig.) [Deutsch] Das neue elektronische-Stabilitaets-Programm (ESP), von Mercedes-Benz ab Maerz 1995 als Weltneuheit angeboten, stellt eine konsequente Weiterentwicklung des Antiblockier-Bremssystems (ABS) und der Antriebsschlupfregelung (ASR) dar. Eine erweiterte Fahrzustandserfassung durch Lenkradwinkel-, Giergeschwindigkeit- und Bremsdrucksensor, eine Hydraulik, die jedes Rad individuell abbremsen kann, angesteuert durch eine komplexe Regelungslogik, erlauben erstmals eine Ueberwachung und aktive Regelung des querdynamischen Fahrzustands bis in den Grenzbereich. Die Beherrschbarkeit des Fahrzeugs wird in kritischen Situationen (z.B. starkes Ueber- oder Untersteuern) entscheidend verbessert. (orig.)

  2. A Randomised Control Trial of the Impact of a Computer-Based Activity Programme upon the Fitness of Children with Autism

    Directory of Open Access Journals (Sweden)

    Kathleen Dickinson

    2014-01-01

    Full Text Available The poor levels of fitness in children with autism are prompting concern for the children’s future health. This study looked to assess if a computer-based activity programme could improve fitness levels (as reflected in cardiopulmonary function of these children, and achieve a reduction in their body mass index. In a randomised controlled trial, 50 children with autism (of which 33 were under the age of 11 years and 39 were boys were allocated to an intervention group which encouraged them to use the Nintendo Wii and the software package “Mario and Sonics at the Olympics” in addition to their routine physical education classes. 50 children with autism (34 under the age of 11 years and 40 being boys acted as controls. At the end of one year, analysis of the changes in scores using analysis of covariance (ANCOVA on the Eurofit fitness tests showed that the intervention group had made statistically significant improvement on all tests other than flexibility. These improvements were also significantly better than controls. This type of intervention appears to be an effective addition to standard fitness training in order to help children with autism improve their fitness levels.

  3. Teaching in English-medium programmes

    DEFF Research Database (Denmark)

    Lauridsen, Karen M.; Cozart, Stacey Marie

    in such a way that they take into account their students’ diverse cultural and linguistic backgrounds and use them as a strength in the classroom; and they should be able to engage all students in joint learning activities so that both the Danish and the international students benefit from the programme......This contribution describes and discusses the module Teaching in English-medium programmes, an elective module offered as part of the teacher training programme for assistant professors (“adjunktpædagogikum”) at Aarhus University. In order to complete the whole programme, assistant professors must...... have at least one such elective module (http://upnet.au.dk/adjunktkursus/). Aarhus University offers the teacher training programme in Danish and in English for international faculty. Teaching in English-medium programmes is part of the Danish track, but taught through English. Building...

  4. The Winfrith DSN programme

    International Nuclear Information System (INIS)

    Francescon, S.

    1963-05-01

    The programme, which is written in the Fortran language, solves the Carlson discrete S n approximation to the Boltzmann transport equation in cylindrical geometry. This report describes the input and output facilities of the WINFRITH DSN programme and the associated editing programme WED. (author)

  5. The Winfrith DSN programme

    Energy Technology Data Exchange (ETDEWEB)

    Francescon, S [General Reactor Physics Division, Atomic Energy Establishment, Winfrith, Dorchester, Dorset (United Kingdom)

    1963-05-15

    The programme, which is written in the Fortran language, solves the Carlson discrete S{sub n} approximation to the Boltzmann transport equation in cylindrical geometry. This report describes the input and output facilities of the WINFRITH DSN programme and the associated editing programme WED. (author)

  6. UNESCO's Ethics Education Programme.

    NARCIS (Netherlands)

    Have, H.A.M.J. ten

    2008-01-01

    Unesco initiated the Ethics Education Programme in 2004 at the request of member states to reinforce and increase the capacities in the area of ethics teaching. The programme is focused on providing detailed information about existing teaching programmes. It also develops and promotes teaching

  7. A reappraisal of the virtues of private sector employment programmes

    DEFF Research Database (Denmark)

    Graversen, Brian Krogh; Jensen, Peter

    2010-01-01

    This paper evaluates the employment effects of active labour market programmes for Danish welfare benefit recipients, focusing on private sector employment (PSE) programmes. Using a latent variable model that allows for heterogeneous treatment effects among observationally identical persons, we...

  8. National Leprosy Eradication Programme (NLEP

    Directory of Open Access Journals (Sweden)

    Shetty Sushant

    1997-01-01

    Full Text Available This article traces the history of the growth and development of our National Leprosy Eradication Programme (NLEP. The aims, strategy, means of eradication, the organizational structure have been discussed. Since the beginning of this programme, the prevalence rate and disability rate have shown a sharp decline. The number of cases detected and under treatment have also increased. The achievement made has been possible due to an excellent organization of leprosy relief work under NLEP with the active cooperation of the non- governmental organizations. Now that leprosy is on the decline, the need of education and rehabilitation of patients assumes a greater importance.

  9. Effects of a standard provision versus an autonomy supportive exercise referral programme on physical activity, quality of life and well-being indicators: a cluster randomised controlled trial.

    Science.gov (United States)

    Duda, Joan L; Williams, Geoffrey C; Ntoumanis, Nikos; Daley, Amanda; Eves, Frank F; Mutrie, Nanette; Rouse, Peter C; Lodhia, Rekha; Blamey, Ruth V; Jolly, Kate

    2014-01-29

    The National Institute for Health and Clinical Excellence in the UK has recommended that the effectiveness of ongoing exercise referral schemes to promote physical activity should be examined in research trials. Recent empirical evidence in health care and physical activity promotion contexts provides a foundation for testing the feasibility and impact of a Self Determination Theory-based (SDT) exercise referral consultation. An exploratory cluster randomised controlled trial comparing standard provision exercise referral with an exercise referral intervention grounded in Self Determination Theory. Individuals (N = 347) referred to an exercise referral scheme were recruited into the trial from 13 centres.Outcomes and processes of change measured at baseline, 3 and 6-months: Minutes of self-reported moderate or vigorous physical activity (PA) per week (primary outcome), health status, positive and negative indicators of emotional well-being, anxiety, depression, quality of life (QOL), vitality, and perceptions of autonomy support from the advisor, need satisfaction (3 and 6 months only), intentions to be active, and motivational regulations for exercise.Blood pressure and weight were assessed at baseline and 6 months. Perceptions of the autonomy support provided by the health and fitness advisor (HFA) did not differ by arm. Between group changes over the 6-months revealed significant differences for reported anxiety only. Within arm contrasts revealed significant improvements in anxiety and most of the Dartmouth CO-OP domains in the SDT arm at 6 months, which were not seen in the standard exercise referral group. A process model depicting hypothesized relationships between advisor autonomy support, need satisfaction and more autonomous motivation, enhanced well being and PA engagement at follow up was supported. Significant gains in physical activity and improvements in quality of life and well-being outcomes emerged in both the standard provision exercise

  10. Effects of a standard provision versus an autonomy supportive exercise referral programme on physical activity, quality of life and well-being indicators: a cluster randomised controlled trial

    Science.gov (United States)

    2014-01-01

    Background The National Institute for Health and Clinical Excellence in the UK has recommended that the effectiveness of ongoing exercise referral schemes to promote physical activity should be examined in research trials. Recent empirical evidence in health care and physical activity promotion contexts provides a foundation for testing the feasibility and impact of a Self Determination Theory-based (SDT) exercise referral consultation. Methods An exploratory cluster randomised controlled trial comparing standard provision exercise referral with an exercise referral intervention grounded in Self Determination Theory. Individuals (N = 347) referred to an exercise referral scheme were recruited into the trial from 13 centres. Outcomes and processes of change measured at baseline, 3 and 6-months: Minutes of self-reported moderate or vigorous physical activity (PA) per week (primary outcome), health status, positive and negative indicators of emotional well-being, anxiety, depression, quality of life (QOL), vitality, and perceptions of autonomy support from the advisor, need satisfaction (3 and 6 months only), intentions to be active, and motivational regulations for exercise. Blood pressure and weight were assessed at baseline and 6 months. Results Perceptions of the autonomy support provided by the health and fitness advisor (HFA) did not differ by arm. Between group changes over the 6-months revealed significant differences for reported anxiety only. Within arm contrasts revealed significant improvements in anxiety and most of the Dartmouth CO-OP domains in the SDT arm at 6 months, which were not seen in the standard exercise referral group. A process model depicting hypothesized relationships between advisor autonomy support, need satisfaction and more autonomous motivation, enhanced well being and PA engagement at follow up was supported. Conclusions Significant gains in physical activity and improvements in quality of life and well-being outcomes emerged

  11. Modernization programme at Dukovany NPP

    International Nuclear Information System (INIS)

    Trnka, M.

    2000-01-01

    The main goal of each NPP is to produce electricity safely, economically and without influence to environment. For Dukovany NPP it means to upgrade all documentation and perform the Equipment Upgrading Programme. All these activities are time and money consuming and therefore the determination of priority of all items was necessary. In the presentation there are mentioned some important changes in documentation, results of PSA studies and reason for Equipment Upgrading Programme performance. It was selected the most important item from the list of Equipment Upgrading Programme the I and C upgrading. Management has decided that Dukovany NPP will become among the best NPPs with WWER type of reactor. It seems this decision is the best way how to extend lifetime of the NPP. (author)

  12. Intracranial intrasellar kissing carotid arteries: case report Artérias carótidas intracranianas intra-selares "que se beijam": relato de caso

    Directory of Open Access Journals (Sweden)

    Arthur de Azambuja Pereira Filho

    2007-06-01

    Full Text Available Intracranial "kissing" carotid arteries are a rare variant of the carotid arteries, where both internal carotid arteries deviate medially and touch each other near the midline within the sphenoid sinus or the sphenoid bone, including the sella. This anomaly is particularly important since it may cause or mimic pituitary disease and also may complicate transsphenoidal surgery. We report a rare case of intracranial intrasellar kissing carotid arteries in a 57-years-old woman that was submitted to a computed tomography angiography during investigation of a sudden headache, and to discuss the clinical relevance of this radiological finding.Artérias carótidas intracranianas "que se beijam" representam rara variação da anatomia arterial, onde ambas as artérias carótidas internas desviam-se medialmente e tocam-se próximo à linha media dentro do seio esfenoidal ou do osso esfenóide, incluindo a sela túrcica. Essa anomalia é particularmente importante, pois pode causar ou simular doença pituitária e ainda pode complicar uma cirurgia transesfenoidal. Relatamos um raro caso de artérias carótidas intracranianas "que se beijam" em mulher de 57 anos, a qual foi investigada por angiotomografia por quadro de cefaléia súbita. Discutimos a relevância clínica desse achado radiológico.

  13. Natural variation in rosette size under salt stress conditions corresponds to developmental differences between Arabidopsis accessions and allelic variation in the LRR-KISS gene

    KAUST Repository

    Julkowska, Magdalena

    2016-02-11

    Natural variation among Arabidopsis accessions is an important genetic resource to identify mechanisms underlying plant development and stress tolerance. To evaluate the natural variation in salinity stress tolerance, two large-scale experiments were performed on two populations consisting of 160 Arabidopsis accessions each. Multiple traits, including projected rosette area, and fresh and dry weight were collected as an estimate for salinity tolerance. Our results reveal a correlation between rosette size under salt stress conditions and developmental differences between the accessions grown in control conditions, suggesting that in general larger plants were more salt tolerant. This correlation was less pronounced when plants were grown under severe salt stress conditions. Subsequent genome wide association study (GWAS) revealed associations with novel candidate genes for salinity tolerance such as LRR-KISS (At4g08850), flowering locus KH-domain containing protein and a DUF1639-containing protein. Accessions with high LRR-KISS expression developed larger rosettes under salt stress conditions. Further characterization of allelic variation in candidate genes identified in this study will provide more insight into mechanisms of salt stress tolerance due to enhanced shoot growth.

  14. Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stents.

    Science.gov (United States)

    Chen, S L; Zhang, J J; Ye, F; Chen, Y D; Patel, T; Kawajiri, K; Lee, M; Kwan, T W; Mintz, G; Tan, H C

    2008-06-01

    Classical crush has a lower rate of final kissing balloon inflation (FKBI) immediately after percutaneous coronary intervention (PCI). The double kissing (DK) crush technique has the potential to increase the FKBI rate, and no prospective studies on the comparison of classical with DK crush techniques have been reported. Three hundred and eleven patients with true bifurcation lesions were randomly divided into classical (n = 156) and DK crush (n = 155) groups. Clinical and angiographic details at follow-up at 8 months were indexed. The primary end point was major adverse cardiac events (MACE) including myocardial infarction, cardiac death and target lesion revascularization (TLR) at 8 months. FKBI was 76% in the classical crush group and 100% in the DK group (P DK crush group. Cumulative 8 month MACE was 24.4% in the classical crush group and 11.4% in the DK crush group (P = 0.02). The TLR-free survival rate was 75.4% in the classical crush group and 89.5% in the DK crush group (P = 0.002). DK crush technique has the potential of increasing FKBI rate and reducing stent thrombosis, with a further reduction of TLR and cumulative MACE rate at 8 months.

  15. Love is more than just a kiss: a neurobiological perspective on love and affection.

    Science.gov (United States)

    de Boer, A; van Buel, E M; Ter Horst, G J

    2012-01-10

    Love, attachment, and truth of human monogamy have become important research themes in neuroscience. After the introduction of functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET), neuroscientists have demonstrated increased interest in the neurobiology and neurochemistry of emotions, including love and affection. Neurobiologists have studied pair-bonding mechanisms in animal models of mate choice to elucidate neurochemical mechanisms underlying attachment and showed possible roles for oxytocin, vasopressin, and dopamine and their receptors in pair-bonding and monogamy. Unresolved is whether these substances are also critically involved in human attachment. The limited number of available imaging studies on love and affection is hampered by selection bias on gender, duration of a love affair, and cultural differences. Brain activity patterns associated with romantic love, shown with fMRI, overlapped with regions expressing oxytocin receptors in the animal models, but definite proof for a role of oxytocin in human attachment is still lacking. There is also evidence for a role of serotonin, cortisol, nerve growth factor, and testosterone in love and attachment. Changes in brain activity related to the various stages of a love affair, gender, and cultural differences are unresolved and will probably become important research themes in this field in the near future. In this review we give a resume of the current knowledge of the neurobiology of love and attachment and we discuss in brief the truth of human monogamy. Copyright © 2011 IBRO. Published by Elsevier Ltd. All rights reserved.

  16. Photovoltaic programme - edition 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration area in Switzerland. Progress in the area of future solar cell technologies, modules and building integration, system technologies, planning and operating aids is summarised. Also, PV for applications in developing countries, thermo-photovoltaics and international co-operation are commented on. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and noise barriers as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and further PV-related topics are summarised. This volume also presents the abstracts of reports made by the project managers of 73 research and pilot and demonstration projects in these areas for 2002.

  17. Photovoltaic programme - edition 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration area in Switzerland. Progress in the area of future solar cell technologies, modules and building integration, system technologies, planning and operating aids is summarised. Also, PV for applications in developing countries, thermo-photovoltaics and international co-operation are commented on. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and noise barriers as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and further PV-related topics are summarised. This volume also presents the abstracts of reports made by the project managers of 73 research and pilot and demonstration projects in these areas for 2002.

  18. Education, Training and the Euratom Framework Programme

    International Nuclear Information System (INIS)

    Jouve, A.; Van Goethem, G.; )

    2009-01-01

    The maintaining of knowledge implies education and training programmes that ensure not only the instruction of students and trainees but also the transfer of knowledge across generations. This is especially important for research in the Euratom field in the present context of nuclear renaissance. DG-Research is responsible for the implementation of the Euratom Framework Programme on nuclear research and training. Through these activities, it is striving to promote the integration of national radiation protection research programmes in Europe, including education and training in radiation protection. These education and training activities supported in the Euratom Programme are helping to establish top-quality teaching modules assembled into masters programmes or higher-level training packages jointly qualified and mutually recognised across the EU. This Euratom approach is entirely in line with the Bologna process. This paper presents and discusses the various actions in education and training in radiation protection supported by DG- Research. (authors)

  19. Perbandingan Gratification Sought Dan Gratification Obtained Pendengar Terhadap Program Stasiun Radio (Studi Komparatif tentang Motif dan Kepuasan Pendengar terhadap Program Stasiun Radio Kiss FM dan Prambors Medan di Kalangan Mahasiswa FISIP USU

    OpenAIRE

    Hutapea, Darma Lestari

    2011-01-01

    Penelitian ini bertujuan untuk membandingkan kepuasan ynag dicari (gratification sought) dan kepuasan yang diperoleh (gratification obtained) pendengar radio Kiss FM dan Prambors FM Medan dengan menggunakan perspektif Uses and Gratification. Model ini menekankan bahwa khalayak adalah pihak yang aktif terhadap penggunaan media. Khalayak bebas mengkonsumsi media yang disukainya. Sampel dalam penelitian ini adalah mahasiswa Fakultas Ilmu Sosial dan Ilmu Politik. Jumlah sampel y...

  20. The development and pilot testing of the self-management programme of activity, coping and education for chronic obstructive pulmonary disease (SPACE for COPD).

    Science.gov (United States)

    Apps, Lindsay D; Mitchell, Katy E; Harrison, Samantha L; Sewell, Louise; Williams, Johanna E; Young, Hannah Ml; Steiner, Michael; Morgan, Mike; Singh, Sally J

    2013-01-01

    There is no independent standardized self-management approach available for chronic obstructive pulmonary disease (COPD). The aim of this project was to develop and test a novel self-management manual for individuals with COPD. Participants with a confirmed diagnosis of COPD were recruited from primary care. A novel self-management manual was developed with health care professionals and patients. Five focus groups were conducted with individuals with COPD (N = 24) during development to confirm and enhance the content of the prototype manual. The Self-management Programme of Activity, Coping and Education for Chronic Obstructive Pulmonary Disease (SPACE for COPD) manual was developed as the focus of a comprehensive self-management approach facilitated by health care professionals. Preference for delivery was initial face-to-face consultation with telephone follow-up. The SPACE for COPD manual was piloted with 37 participants in primary care. Outcome measures included the Self-Report Chronic Respiratory Questionnaire, Incremental Shuttle Walk Test, and Endurance Shuttle Walking Test (ESWT); measurements were taken at baseline and 6 weeks. The pilot study observed statistically significant improvements for the dyspnea domain of the Self-Report Chronic Respiratory Questionnaire and ESWT. Dyspnea showed a mean change of 0.67 (95% confidence interval 0.23-1.11, P = 0.005). ESWT score increased by 302.25 seconds (95% confidence interval 161.47-443.03, P COPD. The program, incorporating the SPACE for COPD manual, appears to provoke important changes in exercise capacity and breathlessness for individuals with COPD managed in primary care.

  1. "Not easy at all but I am trying": barriers and facilitators to physical activity in a South African cohort of people living with HIV participating in a home-based pedometer walking programme.

    Science.gov (United States)

    Roos, Ronel; Myezwa, Hellen; van Aswegen, Helena

    2015-01-01

    The promotion of physical activity is encouraged in people living with HIV and AIDS (PLWHA) as a means of promoting wellness and health. Adherence to programmes that promote exercise is often reduced, and home-based programmes are suggested to improve adherence. This study investigated the personal and environmental factors that cause barriers and facilitators of physical activity in a home-based pedometer walking programme as a means of highlighting adherence challenges. An observational study nested in a randomised controlled trial was conducted in a cohort of South African PLWHA on antiretroviral therapy over a six-month period. Descriptive analysis and qualitative content analysis of 42 participants who underwent physical activity modification assisted with data review. The mean age of the sample was 38.7 (±8.9) years, consisted mostly of women (n = 35; 83.3%) who were employed (n = 19; 45.2%) but earning very little (less than R500 per month) and often single or widowed (n = 23; 54.8%). Barriers to physical activity identified included physical complaints, e.g., low-energy levels; psychological complaints, e.g., stress levels; family responsibility, e.g., being primary caregivers; the physical environment, e.g., adverse weather conditions; social environment, e.g., domestic abuse and crime; and workplace, e.g., being in a sedentary job. Facilitators of physical activity included support and encouragement from friends and family, religious practices during worship and community environment, e.g., having access to parks and sport fields. The study is of benefit as it highlights personal and environmental factors that need to be considered when developing or implementing a home-based walking programme in PLWHA.

  2. A qualitative study of patients' experiences of participating in SPACE for COPD: a Self-management Programme of Activity, Coping and Education.

    Science.gov (United States)

    Apps, Lindsay D; Harrison, Samantha L; Mitchell, Katy E; Williams, Johanna E A; Hudson, Nicky; Singh, Sally J

    2017-10-01

    The aim of this study was to understand experiences of participation in a supported self-management programme for chronic obstructive pulmonary disease (COPD). There is a wealth of clinical trials examining the outcomes of self-management interventions for individuals with COPD, but current understanding regarding patients' perspectives of such complex interventions is limited. Further insight may help to tailor self-management interventions and maximise patient engagement. Semi-structured interviews were conducted with individuals participating in a self-management programme, SPACE for COPD. Interviews took place at 6 weeks and 6 months following the programme. Data were analysed at each time point using inductive thematic analysis, and subsequently re-examined together. 40 interviews were undertaken and four themes emerged from the analysis: perceptions of the programme; lifestyle changes; social support; and disrupting factors and barriers to maintaining routines. SPACE for COPD was acceptable to participants in this study. The importance of education and social support was emphasised at both time points studied, but there were challenges such as comorbidities, ill health of family members and limited maintenance of exercise behaviours over the longer term. Further consideration of the role of carers and partners may help to improve adherence to self-management programmes once healthcare professional support has stopped.

  3. Cigotica programme: pediatric experiences

    Directory of Open Access Journals (Sweden)

    Lešović Snežana

    2011-01-01

    Full Text Available Introduction The alarming spread of obesity epidemic in children and adolsecents, as well as the absence of tested and efficient measures and programmes on obesity preven­tion indicate the necessity for the establishment of the Centre for the prevention, treatment and rehabilitation of obesity in children and adolescents and the 'Cigotica Programme' at the Special Hospital 'Zlatibor'. The advantage of the 'Cigotica' Programme is the multidisciplinary approach to treating obese children, which implies specific education, dietetic interventions with the reduction in the total daily calorie intake, physical activity, medical, educational and psychological support, change of behavior and lifestyle. Objective To define obesity complications, metabolic risk factors and treatment effects on body composition and metabolic parameters in adolescents participating in the 'Cigotica' Programme. Method 1,030 adolescents were examined (498 girls and 532 boys, aged 12 to 18, average age 15.45, diagnosed with primary obesity, hospitalized at the Centre for the prevention, treatment and rehabilitation of obesity in children and adolescents at the Special Hospital 'Zlatibor', in the period from 27/07/2008 to 03/10/2010. Hospitalization lasted 21 days. Obesity criterion was body mass index (BMI > +2 SD . Body The Special Hospital for the Thyroid Gland and Metabolism Zlatibor mass, BMI, % of fat were obtained by means of Tanita scales for determining body composition using the impendence method. Apart from medical examination, blood pressure was also taken. The levels of triglycerides, total HDL and LDL cholesterols, uric acids and glycemia were determined on the second and twenty-first day of hospitalization after a 12-day fasting period. Results After the multidisciplinary treatment, the average reduction in body mass (p< 0.05 in all adolescents was 5.92 ± 2.71 kg, in boys - 6.24 ±3.24 kg, and in girls -5.86±2.4. During the 21-day hospitalization, the average

  4. Methadone maintenance treatment programme reduces criminal activity and improves social well-being of drug users in China: a systematic review and meta-analysis.

    Science.gov (United States)

    Sun, Hua-Min; Li, Xiao-Yan; Chow, Eric P F; Li, Tong; Xian, Yun; Lu, Yi-Hua; Tian, Tian; Zhuang, Xun; Zhang, Lei

    2015-01-08

    % CI 52.4% to 66.8%) and 75.0% (95% CI 69.0% to 80.2%) at 12 months after treatment initiation, respectively. MMT has significantly reduced criminal activity, and improved employment rate and social well-being, of clients of the MMT programme. MMT is an effective measure to help drug users to resume societal and familial functions in China. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. HADES RV programme with HARPS-N at TNG. VII. Rotation and activity of M-dwarfs from time-series high-resolution spectroscopy of chromospheric indicators

    Science.gov (United States)

    Mascareño, A. Suárez; Rebolo, R.; González Hernández, J. I.; Toledo-Padrón, B.; Perger, M.; Ribas, I.; Affer, L.; Micela, G.; Damasso, M.; Maldonado, J.; González-Alvarez, E.; Leto, G.; Pagano, I.; Scandariato, G.; Sozzetti, A.; Lanza, A. F.; Malavolta, L.; Claudi, R.; Cosentino, R.; Desidera, S.; Giacobbe, P.; Maggio, A.; Rainer, M.; Esposito, M.; Benatti, S.; Pedani, M.; Morales, J. C.; Herrero, E.; Lafarga, M.; Rosich, A.; Pinamonti, M.

    2018-05-01

    We aim to investigate the presence of signatures of magnetic cycles and rotation on a sample of 71 early M-dwarfs from the HADES RV programme using high-resolution time-series spectroscopy of the Ca II H&K and Hα chromospheric activity indicators, the radial velocity series, the parameters of the cross correlation function and the V -band photometry. We used mainly HARPS-N spectra, acquired over 4 yr, and add HARPS spectra from the public ESO database and ASAS photometry light-curves as support data, extending the baseline of the observations of some stars up to 12 yr. We provide log10(R'HK) measurements for all the stars in the sample, cycle length measurements for 13 stars, rotation periods for 33 stars and we are able to measure the semi-amplitude of the radial velocity signal induced by rotation in 16 stars. We complement our work with previous results and confirm and refine the previously reported relationships between the mean level of chromospheric emission, measured by the log10(R'HK), with the rotation period, and with the measured semi-amplitude of the activity induced radial velocity signal for early M-dwarfs. We searched for a possible relation between the measured rotation periods and the lengths of the magnetic cycle, finding a weak correlation between both quantities. Using previous v sin i measurements we estimated the inclinations of the star's poles to the line of sight for all the stars in the sample, and estimate the range of masses of the planets GJ 3998 b and c (2.5-4.9 and 6.3-12.5 M⊕), GJ 625 b (2.82 M⊕), GJ 3942 b (7.1-10.0 M⊕) and GJ 15A b (3.1-3.3 M⊕), assuming their orbits are coplanar with the stellar rotation. Based on: observations made with the Italian Telescopio Nazionale Galileo (TNG), operated on the island of La Palma by the INAF - Fundación Galileo Galilei at the Roche de Los Muchachos Observatory of the Instituto de Astrofísica de Canarias (IAC); observations made with the HARPS instrument on the ESO 3.6-m telescope

  6. The research group, the conference programme and academic training in safety promotion - a report of the activities at Karolinska Institutet, Sweden.

    Science.gov (United States)

    Hörte, Lars-Gunnar; Jansson, Bjarne; Svanström, Leif

    2012-01-01

    The research group was established in 1967 at Lund University and moved to Karolinska Institutet in 1980. Work began with epidemiological studies of all injuries in the local community in support of various experimental local interventions. An important element was the creation of 'surveillance systems' in healthcare. The work resulted in the establishment of a WHO Collaborating Centre and an international safety-building programme called 'Safe Communities'. In parallel, training at both master's and doctoral level and the building of a conference programme were embarked upon. The research group consists of three sections. Specific efforts are being made by some countries to address their own injury problems.

  7. Quality assurance programme for the LVR-15 nuclear research reactor

    International Nuclear Information System (INIS)

    1995-03-01

    The document specifies all aspects of the quality assurance programme for the LVR-15 nuclear research reactor. The programme addresses the organization and responsibilities, basic quality assurance activities, and identification of management, planning, and working documents necessary to implement the programme. (P.A.)

  8. Students' Assessment Of Farm Practical Programme In Selected ...

    African Journals Online (AJOL)

    Students' Assessment Of Farm Practical Programme In Selected Universities Of Southwestern, Nigeria. ... Journal of Agriculture, Forestry and the Social Sciences ... Students reported that lack of planning, improper implementation of activities lined up for the programme, lack of fund to properly finance the programme and ...

  9. Screening of preschool and school children for cystic fibrosis with the chloride electrode and neutron activation analysis. Part of a coordinated programme on medical applications of activation analysis

    International Nuclear Information System (INIS)

    Gurson, C.T.

    1975-10-01

    A screening study was performed on 9,685 infants and children between 0 and 7 years of age living in the city of Istanbul. 2,511 of the subjects (''normals'') were kindergarten and school children and the remainder were children who had been brought to the casualty outpatient departments of two large hospitals. The purposes of the investigation were twofold, first to determine the prevalence of cystic fibrosis in a normal versus a sick population of children, and second to compare sweat-chloride vis-a-vis nail-sodium as indicators of the disease. Sweat-chloride was determined in all subjects by the use of a chloride specific electrode; nail sodium was determined in 1122 subjects by neutron activation analysis. These measurements led to the identification of seven cystic fibrosis cases in the outpatient group (frequency = 0.1%) and none in the kindergarten/school group. Sweat-chloride gave 0.7% false positives and no false negatives; nailsodium gave 14.7% false positives and 0.1% false negatives. It is concluded that nail-sodium is a much less effective indicator of cystic fibrosis than sweat-chloride and its use can probably not be justified except in certain special circumstances. Furthermore it would appear that the screening of outpatient cases rather than the whole population of children is a more cost-effective method for the detection of cystic fibrosis

  10. Norwegian High-School Students Internship Programme

    CERN Multimedia

    2017-01-01

    The High-School Students Internship Programme (HSSIP is a programme developed by the ECO group’s Teacher and Student Programmes section to engage students from a young age with scientific research and innovation. Norway was selected as one out of five countries for the pilot programmes run in 2017. Out of some 150 applications, 10 boys and 14 girls, from Longyearbyen (Svalbard) in the North to Flekkefjord in the South, were invited to participate in the Norwegian programme that took place from 15 October - 28 October. The youngsters were offered an intense two-week internship at CERN, during which they took part in many diverse activities. Accompanied by mentors, the students got a deeper insight into how CERN supports particle physics by working on their own projects and through a variety of visits.

  11. Development of a training programme for home health care workers to promote preventive activities focused on a healthy lifestyle : an intervention mapping approach

    NARCIS (Netherlands)

    Walters, Maaike E.; Dijkstra, Arie; de Winter, Andrea F.; Reijneveld, Sijmen A.

    2015-01-01

    Background: Lifestyle is an important aspect in maintaining good health in older adults, and home health care (HHC) workers can play an important role in promoting a healthy lifestyle. However, there is limited evidence in the literature regarding how to develop an effective training programme to

  12. The IAEA Accident Management Programme

    International Nuclear Information System (INIS)

    Kabanov, L.; Jankowski, M.; Mauersberger, H.

    1993-01-01

    Accident prevention and mitigation programmes and the Emergency Response System (ERS) are important elements of the Agency's activities in the area of nuclear power plant (NPP) safety. Safety Codes and Guides on siting, design, quality assurance and the operation of NPPs have been produced and are used by NPP operating organizations. Nuclear safety evaluation services are provided by the IAEA. The Emergency Response System and the International Nuclear Event Scale (INES) have been developed. The framework for the development of an accident management programme has been set up. The main goal is to develop an Accident Management Manual to provide a systematic, structured approach to the development and implementation of an accident management programme at NPPs. An outline of the Manual has been distributed and the first draft is available. The component parts are: Co-ordinated research programmes (CRPs) on severe accident management and containment behaviour; the use of vulnerability analysis; mitigation of the effects of hydrogen, and generic symptom oriented emergency operating procedures. The IAEA provides guidance by the dissemination of information on methods for accident management; collates information on approaches in this field in different organizations and countries; and arranges exchange of experience and the promulgation of knowledge through the training of NPP managers and senior technical staff. (orig.)

  13. The IAEA Accident Management Programme

    Energy Technology Data Exchange (ETDEWEB)

    Kabanov, L.; Jankowski, M.; Mauersberger, H. (International Atomic Energy Agency, Vienna (Austria))

    1993-02-01

    Accident prevention and mitigation programmes and the Emergency Response System (ERS) are important elements of the Agency's activities in the area of nuclear power plant (NPP) safety. Safety Codes and Guides on siting, design, quality assurance and the operation of NPPs have been produced and are used by NPP operating organizations. Nuclear safety evaluation services are provided by the IAEA. The Emergency Response System and the International Nuclear Event Scale (INES) have been developed. The framework for the development of an accident management programme has been set up. The main goal is to develop an Accident Management Manual to provide a systematic, structured approach to the development and implementation of an accident management programme at NPPs. An outline of the Manual has been distributed and the first draft is available. The component parts are: Co-ordinated research programmes (CRPs) on severe accident management and containment behaviour; the use of vulnerability analysis; mitigation of the effects of hydrogen, and generic symptom oriented emergency operating procedures. The IAEA provides guidance by the dissemination of information on methods for accident management; collates information on approaches in this field in different organizations and countries; and arranges exchange of experience and the promulgation of knowledge through the training of NPP managers and senior technical staff. (orig.).

  14. Radiological impact of the Argentine Nuclear Programme

    International Nuclear Information System (INIS)

    Gonzalez, A.J.

    1983-01-01

    An assessment is made of the radiological impact resulting from the activities carried out so far under the Argentine Nuclear Programme, together with a prediction of the impact which could result from the future activities planned under that Programme. The average individual risks and the radiological detriment due to the various activities are determined in terms of the average individual effective dose equivalents and the collective effective dose equivalent commitments. The assessments cover exposures of occupationally exposed workers and the public. The data obtained indicate that both the risks and the resultant detriment are reasonably comparable with those derived from other similar programmes. Moreover, they clearly indicate that the radiological impact of the Programme is tending to decrease with time so that it can be assumed that the radiological impact per unit of practice will be even lower in future. (author)

  15. Reducing musculoskeletal injury and concussion risk in schoolboy rugby players with a pre-activity movement control exercise programme: a cluster randomised controlled trial.

    Science.gov (United States)

    Hislop, Michael D; Stokes, Keith A; Williams, Sean; McKay, Carly D; England, Mike E; Kemp, Simon P T; Trewartha, Grant

    2017-08-01

    Injury risk in youth rugby has received much attention, highlighting the importance of establishing evidence-based injury reduction strategies. To determine the efficacy of a movement control exercise programme in reducing injuries in youth rugby players and to investigate the effect of programme dose on injury measures. In a cluster-randomised controlled trial, 40 independent schools (118 teams, 3188 players aged 14-18 years) were allocated to receive either the intervention or a reference programme, both of which were to be delivered by school coaches. The intervention comprised balance training, whole-body resistance training, plyometric training, and controlled rehearsal of landing and cutting manoeuvres. Time-loss (>24 hours) injuries arising from school rugby matches were recorded by coaches and medical staff. 441 time-loss match injuries (intervention, 233; control, 208) were reported across 15 938 match exposure-hours (intervention, 9083; control, 6855). Intention-to-treat results indicated unclear effects of trial arm on overall match injury incidence (rate ratio (RR)=0.85, 90% confidence limits 0.61 to 1.17), although clear reductions were evident in the intervention arm for concussion incidence (RR=0.71, 0.48 to 1.05). When trial arm comparisons were limited to teams who had completed three or more weekly programme sessions on average, clear reductions in overall match injury incidence (RR=0.28, 0.14 to 0.51) and concussion incidence (RR=0.41, 0.17 to 0.99) were noted in the intervention group. A preventive movement control exercise programme can reduce match injury outcomes, including concussion, in schoolboy rugby players when compared with a standardised control exercise programme, although to realise the greatest effects players should complete the programme at least three times per week. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted

  16. Kiss the Embargo Goodbye

    National Research Council Canada - National Science Library

    Crowther, Glenn A

    2009-01-01

    The embargo on Cuba has been in place for almost 50 years. Although it may have been an appropriate policy response to the Cuban Revolution in the milieu of the Cold War, the reality of the 21st century calls for its abolishment...

  17. The Kiss of Grace

    DEFF Research Database (Denmark)

    Tillisch, Rose Marie

    2004-01-01

    Bernhard af Clairvaux (1090-1153) og Martin Luther (1483-1546) læste begge Gammel Testamente som én lang længsel efter Kristus. De havde dog hver deres favoritter indenfor det gammeltestamentlige korpus. For Bernhard var Højsangen en stadig inspirationskilde, mens Salmernes Bog var grundlag for L...

  18. Swiss breeder research programme

    International Nuclear Information System (INIS)

    1992-01-01

    A new initiative for a Swiss Fast Breeder Research Program has been started during 1991. This was partly the consequence of a vote in Fall 1990, when the Swiss public voted for maintaining nuclear reactors in operation, but also for a moratorium of 10 years, within which period no new reactor project should be proposed. On the other hand the Swiss government decided to keep the option 'atomic reactors' open and therefore it was essential to have programmes which guaranteed that the knowledge of reactor technology could be maintained in the industry and the relevant research organisations. There is also motivation to support a Swiss Breeder Research Program on the part of the utilities, the licensing authorities and the Paul Scherrer Institute (PSI). The utilities recognise the breeder reactor as an advanced reactor system which has to be developed further and might be a candidate, somewhere in the future, for electricity production. In so far they have great interest that a know-how base is maintained in our country, with easy access for technical questions and close attention to the development of this reactor type. The licensing authorities have a legitimate interest that an adequate knowledge of the breeder reactor type and its functions is kept at their disposal. PSI and the former EIR have had for many years a very successful basic research programme concerning breeder reactors, and were in close cooperation with EFR. The activities within this programme had to be terminated owing to limitations in personnel and financial resources. The new PSI research programme is based upon two main areas, reactor physics and reactor thermal hydraulics. In both areas relatively small but valuable basic research tasks, the results of which are of interest to the breeder community, will be carried out. The lack of support of the former Breeder Programme led to capacity problems and finally to a total termination. Therefore one of the problems which had to be solved first was

  19. [Coronary angioplasty simultaneous with the "kissing" technique in a bifurcation lesion: use of a guidewire, and 2 monorail systems of rapid interchange].

    Science.gov (United States)

    Escudero, X

    1996-01-01

    Coronary branch occlusion complicating percutaneous coronary angioplasty has been recognized in certain bifurcation lesions. The utilization of double angioplasty systems simultaneously has been called "kissing" because the image of contact between balloons, and has been utilized as an alternative to protect the jeopardized branch or prevent snowplow lesion of the principal artery. The technological advance with the use of wide lumen catheters and low profile dilation balloons make the application of this technique possible in those type of lesions using a single guiding catheter. The present paper describes one case treated with this technique using conventional angioplasty systems in a complex bifurcating lesion of the circumflex artery. Some technical considerations about the procedure are made.

  20. Fusion technology programme

    International Nuclear Information System (INIS)

    Finken, D.

    1984-04-01

    KfK participates to the Fusion Technology Programme of the European Community. Most of the work in progress addresses the Next European Torus (NET) and the long term technology aspects as defined in the 82/86 programme. A minor part serves to preparation of future contributions and to design studies on fusion concepts in a wider perspective. The Fusion Technology Programme of Euratom covers mainly aspects of nuclear engineering. Plasma engineering, heating, refueling and vacuum technology are at present part of the Physics Programme. In view of NET, integration of the different areas of work will be mandatory. KfK is therefore prepared to address technical aspects beyond the actual scope of the physics experiments. The technology tasks are reported project wise under title and code of the Euratom programme. Most of the projects described here are shared with other European fusion laboratories as indicated in the table annexed to this report. (orig./GG)

  1. Experience from the Inspection of Licensees' Outage Activities, Including Fire Protection Programmes, Event Response Inspections, and the Impact of the Fukushima Daiichi NPP Accident on Inspection Programmes. Workshop Proceedings, Chattanooga, Tennessee, United States, 7-10 April 2014 - Appendix: Compilation of Survey Responses

    International Nuclear Information System (INIS)

    2014-10-01

    This appendix provides the complete compilation of responses received to the questionnaire issued in conjunction with the workshop announcements. The responses are provided as received, with changes made only to the formatting. The OECD Nuclear Energy Agency (NEA) Committee on Nuclear Regulatory Activities (CNRA) Working Group on Inspection Practices (WGIP) sponsored the 12. International Workshop on Nuclear Regulatory Inspection Activities. The workshop was hosted by the U.S. NRC, in Chattanooga, Tennessee, United States of America on 7 -10 April 2014. The three workshop topics that were addressed were as follows: - Inspection of Outage Activities Including Fire Protection Programmes. - Event Response Inspections. - The Impact of Inspection Programmes of the Fukushima Daiichi NPP Accident. Each of the respondents was given the following instructions in relation to their response: - Only one response per country is required. If more than one person from your country is participating, please co-ordinate the responses accordingly. - Please provide responses on separate sheet and clearly identify the questionnaire part and topic. For preparation of the workshop, participants are invited to supply their national inspection approaches used in inspection of events and incidents according to the surveys. Actual issues that were discussed during the workshop were generated by the topic leaders based on the responses submitted by participants with their registration forms. This formats helps to ensure that issues considered most important by the workshop participants are covered during the group discussions. (authors)

  2. Country programme review Republic of Cameroon

    International Nuclear Information System (INIS)

    Cherif, H.C.; Hasling, W.; Hera, C.H.; Maudarbocus, A.Y.; Mtimet, S.

    1993-10-01

    A multi-disciplinary country programme review and programming mission was undertaken to the Republic of Cameroon, from 21 to 25 June 1993. This report reflects the findings and recommendations of the mission and falls into four sections. The first section describes the country profile and includes information about its economy and its development plans and policies. The second reviews the Agency's past and present technical co-operation programmes in Cameroon. The third section deals with a sectoral programme and institutional review, and the fourth section presents possible future technical co-operation activities

  3. Auditing as method of QA programme evaluation

    International Nuclear Information System (INIS)

    Wilhelm, H.

    1980-01-01

    The status and adequacy of a quality assurance programme should be regularly reviewed by the cognizant management. The programme audit is an independent review to determine the compliance with respective quality assurance requirements and to determine the effectiveness of that programme. This lecture gives an introduction of the method to perform audits under the following topics: 1. Definition and purpose of quality audits. 2. Organization of the quality audit function. 3. Unique requirements for auditors. 4. Audit preparation and planning. 5. Conduct of the audit. 6. Reporting the audit results. 7. Follow-up activities. (RW)

  4. Effectiveness of a universal parental support programme to promote healthy dietary habits and physical activity and to prevent overweight and obesity in 6-year-old children: the Healthy School Start Study, a cluster-randomised controlled trial.

    Science.gov (United States)

    Nyberg, Gisela; Sundblom, Elinor; Norman, Åsa; Bohman, Benjamin; Hagberg, Jan; Elinder, Liselotte Schäfer

    2015-01-01

    To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children. A cluster-randomised controlled trial was carried out in areas with low to medium socio-economic status. Participants were six-year-old children (n = 243) and their parents. Fourteen pre-school classes were randomly assigned to intervention (n = 7) and control groups (n = 7). The intervention lasted for 6 months and included: 1) Health information for parents, 2) Motivational Interviewing with parents and 3) Teacher-led classroom activities with children. Physical activity was measured by accelerometry, dietary and physical activity habits and parental self-efficacy through a questionnaire. Body weight and height were measured and BMI standard deviation score was calculated. Measurements were conducted at baseline, post-intervention and at 6-months follow-up. Group differences were examined using analysis of covariance and Poisson regression, adjusted for gender and baseline values. There was no significant intervention effect in the primary outcome physical activity. Sub-group analyses showed a significant gender-group interaction in total physical activity (TPA), with girls in the intervention group demonstrating higher TPA during weekends (p = 0.04), as well as in sedentary time, with boys showing more sedentary time in the intervention group (p = 0.03). There was a significantly higher vegetable intake (0.26 servings) in the intervention group compared to the control group (p = 0.003). At follow-up, sub-group analyses showed a sustained effect for boys. The intervention did not affect the prevalence of overweight or obesity. It is possible to influence vegetable intake in children and girls' physical activity through a parental support programme. The programme needs to be intensified in order to increase effectiveness and sustain the effects long-term. These findings are an

  5. Effectiveness of a universal parental support programme to promote healthy dietary habits and physical activity and to prevent overweight and obesity in 6-year-old children: the Healthy School Start Study, a cluster-randomised controlled trial.

    Directory of Open Access Journals (Sweden)

    Gisela Nyberg

    Full Text Available To develop and evaluate the effectiveness of a parental support programme to promote healthy dietary and physical activity habits and to prevent overweight and obesity in Swedish children.A cluster-randomised controlled trial was carried out in areas with low to medium socio-economic status. Participants were six-year-old children (n = 243 and their parents. Fourteen pre-school classes were randomly assigned to intervention (n = 7 and control groups (n = 7. The intervention lasted for 6 months and included: 1 Health information for parents, 2 Motivational Interviewing with parents and 3 Teacher-led classroom activities with children. Physical activity was measured by accelerometry, dietary and physical activity habits and parental self-efficacy through a questionnaire. Body weight and height were measured and BMI standard deviation score was calculated. Measurements were conducted at baseline, post-intervention and at 6-months follow-up. Group differences were examined using analysis of covariance and Poisson regression, adjusted for gender and baseline values.There was no significant intervention effect in the primary outcome physical activity. Sub-group analyses showed a significant gender-group interaction in total physical activity (TPA, with girls in the intervention group demonstrating higher TPA during weekends (p = 0.04, as well as in sedentary time, with boys showing more sedentary time in the intervention group (p = 0.03. There was a significantly higher vegetable intake (0.26 servings in the intervention group compared to the control group (p = 0.003. At follow-up, sub-group analyses showed a sustained effect for boys. The intervention did not affect the prevalence of overweight or obesity.It is possible to influence vegetable intake in children and girls' physical activity through a parental support programme. The programme needs to be intensified in order to increase effectiveness and sustain the effects long-term. These findings

  6. 'It's like a personal motivator that you carried around wi' you': utilising self-determination theory to understand men's experiences of using pedometers to increase physical activity in a weight management programme.

    Science.gov (United States)

    Donnachie, Craig; Wyke, Sally; Mutrie, Nanette; Hunt, Kate

    2017-05-05

    Self-monitoring using pedometers is an effective behaviour change technique to support increased physical activity (PA). However, the ways in which pedometers operate as motivational tools in adoption and maintenance of PA is not well understood. This paper investigates men's experiences of pedometers as motivational tools both during and after their participation in a 12-week group-based, weight management programme for overweight/obese men, Football Fans in Training (FFIT). Semi-structured telephone interviews were conducted with 28 men, purposively sampled to include men who did and did not achieve 5% weight loss during the programme. Data were analysed thematically utilising the framework approach, using Self-Determination Theory (SDT) - namely concepts of behavioural regulation and the basic needs of relatedness, competence and autonomy - as an analytical lens. During the programme, FFIT's context and fellow participants supported relatedness and encouraged use of the pedometer. The pedometer was seen to provide tangible proof of progress, thus increasing competence for change, whilst the ability to monitor one's own progress and take remedial action supported autonomy; these men portrayed the pedometer as an 'ally'. However, a minority found the pedometer 'dispiriting' or controlling when it evidenced their inability to meet their PA targets. After the programme, some men no longer used the device as they had fully internalised their motivations for increased PA. In contrast, others continued to use pedometers or progressed to other self-monitoring technologies because it was enjoyable and facilitated maintenance of their increased PA. However, the minority of men who experienced the pedometer as controlling no longer used it. They were less successful in achieving 5% weight loss and appeared reliant on external factors, including support from coach and group members, to maintain motivation. These findings show how self-monitoring using pedometers and

  7. Optical programmable metamaterials

    Science.gov (United States)

    Gong, Cheng; Zhang, Nan; Dai, Zijie; Liu, Weiwei

    2018-02-01

    We suggest and demonstrate the concept of optical programmable metamaterials which can configure the device's electromagnetic parameters by the programmable optical stimuli. In such metamaterials, the optical stimuli produced by a FPGA controlled light emitting diode array can switch or combine the resonance modes which are coupled in. As an example, an optical programmable metamaterial terahertz absorber is proposed. Each cell of the absorber integrates four meta-rings (asymmetric 1/4 rings) with photo-resistors connecting the critical gaps. The principle and design of the metamaterials are illustrated and the simulation results demonstrate the functionalities for programming the metamaterial absorber to change its bandwidth and resonance frequency.

  8. NNP Life Management Programmes

    International Nuclear Information System (INIS)

    Hervia Ruperez, F.

    1996-01-01

    Around the world, power station owners are increasingly concerned to optimise Plant Life Management. In response, they are setting up Life Management programmes, of more or less ambitious scope and depth. Strategic, economic and security concerns and the close link between life extension work and the improved maintenance practices that are so important today, will increase and global these programmes for monitoring and conservation or mitigation of ageing. These programmes are all based on knowledge of the precise condition of all components and population with the greatest effect on the economics and safety of the plant, and trends in changes in their condition. (Author)

  9. The European Fusion Programme

    International Nuclear Information System (INIS)

    Palumbo, D.

    1983-01-01

    The European Fusion Programme is coordinated by Euratom and represents a long term cooperative project of Member States of the European Communities in the field of fusion, designed to lead to the joint construction of prototypes. The main lines of the programme proposed for 1982 to 1986 are: (1) the continuation of a strong effort on tokamaks with emphasis on JET construction, operation and upgrading, (2) conceptual design of NET and development of the related technology, and (3) further work on two alternative magnetic confinement systems. The current status and future plans for this programme are discussed in the paper. (author)

  10. Photovoltaic programme, edition 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This comprehensive publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration areas in Switzerland for the year 2003. Progress in future solar cell technologies as well as in the area of modules, building integration and system technologies is summarised. Also, national and international co-operation and multi-national pilot and demonstration projects are commented on. Associated projects such as eco-balances for PV systems, forecasting and modelling tools as well as system monitoring tools are discussed. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and on facades as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and other PV-related topics are summarised. This volume presents a list of 92 projects in the PV area including the appropriate Internet links and is completed with a collection of project abstracts.

  11. Photovoltaic programme, edition 2004

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This comprehensive publication issued by the Swiss Federal Office of Energy's Photovoltaics (PV) Programme presents an overview (in English) of activities and projects in the photovoltaics research and pilot and demonstration areas in Switzerland for the year 2003. Progress in future solar cell technologies as well as in the area of modules, building integration and system technologies is summarised. Also, national and international co-operation and multi-national pilot and demonstration projects are commented on. Associated projects such as eco-balances for PV systems, forecasting and modelling tools as well as system monitoring tools are discussed. In the area of pilot and demonstration projects, component development, PV integration in sloping roofs, on flat roofs and on facades as well as further PV plant are looked at. Also, measurement campaigns, studies, statistics and other PV-related topics are summarised. This volume presents a list of 92 projects in the PV area including the appropriate Internet links and is completed with a collection of project abstracts.

  12. PROPOSAL OF VOIVODESHIP ROAD SAFETY IMPROVEMENT PROGRAMME

    OpenAIRE

    Tomasz SZCZURASZEK; Jan KEMPA

    2016-01-01

    The article presents a proposal of the ‘GAMBIT KUJAWSKO-POMORSKI’ Road Safety Improvement Programme. The main idea of the Programme is to establish and initiate systems that will be responsible for the most important areas of activity within road safety, including road safety control, supervision, and management systems in the whole Voivodeship. In total, the creation and start of nine such systems has been proposed, namely: the Road Safety Management, the Integrated Road Rescue Service, the ...

  13. The QUENCH programme at Forschungszentrum Karlsruhe (FZK)

    International Nuclear Information System (INIS)

    Steinbrueck, M.; Schanz, G.; Sepold, L.; Stuckert, J.; Hering, W.; Homann, C.; Miassoedov, A.

    2004-01-01

    The QUENCH programme at FZK was launched to investigate the hydrogen source term during reflood of an overheated reactor core. It consists of large scale bundle experiments, separate-effects tests, modelling activities and application and validation of severe fuel damage (SFD) code systems. The paper describes the experimental part of the programme, namely the experimental facilities and test rigs as well as selected results obtained during the recent years. (author)

  14. Fellows, Associates & Students Programmes

    CERN Document Server

    2005-01-01

    The present document reviews the CERN Fellows, Associates and Students Programmes emphasizing the developments since 2000, when the previous review was presented to the Scientific Policy Committee, Finance Committee and Council (CERN/2325), and makes proposals for the coming five years. In summary, it is proposed to â?¢ Simplify the payment scheme for the Paid Scientific Associates Programme, which will no longer depend on candidateâ??s home support and age; â?¢ Broaden the scope of the Fellowship Programme, in order to facilitate the recruitment of young graduates in computing and engineering. Age-related eligibility conditions and payment levels will be replaced with experience-based criteria; â?¢ Modify subsistence rates for the Doctoral and Technical Student Programme in order to harmonize CERNâ??s payment levels with those offered by other research establishments. This document is presented for discussion and recommendation by the Scientific Policy Committee and approval by the Council. Additiona...

  15. (ARV) treatment training programme

    African Journals Online (AJOL)

    Winnie

    Keywords:ARV, training, evaluation, HIV, health care provider. RÉSUMÉ .... workers, adequate laboratory facilities for measuring viral load and .... questionnaire guide, the head of unit of the ART ...... begins its scale-up programme. Some of ...

  16. The French nuclear programme

    International Nuclear Information System (INIS)

    Bacher, Pierre

    1987-01-01

    France has a civil nuclear power generation programme second only to the USA with 49 nuclear units in operation and 13 under construction. The units in service are described. These include 33 PWR 900 MW and 9 PWR 1300 MW units. The electricity consumption and generation in France is illustrated. The absence of a powerful anti-nuclear lobby and two main technical options have contributed to the success of the French nuclear programme. These are the PWR design and the plant standardization policy which allows the setting up of an effective industrial complex (eg for analysis of operating conditions and of safety and reliability information). The programme and the reasons for its success are reviewed. Research programmes and future plans are also discussed. (UK)

  17. Elukestva õppe programm : Erasmus+

    Index Scriptorium Estoniae

    2014-01-01

    Erasmus+ programm liidab senised koostööprogrammid „Euroopa elukestva õppe programm“, „Euroopa Noored“ ning Euroopa komisjoni rahvusvahelised kõrgharidusprogrammid. Elukestva õppe programmi 2013 kokkuvõte

  18. The European Framework Programme under way

    CERN Multimedia

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1 January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 B-Euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding of frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 December...

  19. The European Framework Programme under way

    CERN Multimedia

    2007-01-01

    The new European Framework Programme - FP7 - has recently started and will offer various possibilities for CERN to participate in EU co-funded projects for research and technological development. In December 2006, the Council of the European Union (EU) formally adopted the 7th European Framework Programme for research, technological development and demonstration activities (FP7). FP7 started on 1st January 2007 and will cover the period 2007 to 2013. With a total budget of 50.5 billion euros, FP7 is the largest Framework Programme in the history of the EU. FP7 consists of four major sub-programmes, referred to as 'Specific Programmes'. 'Cooperation' is focused on collaborative research and is divided into 10 research themes. 'Ideas' is a new EU programme for funding frontier research in all fields of science. 'Capacities' aims at strengthening the research capacities in Europe. Finally, 'People' succeeds the previous Marie Curie Programmes and targets the development of Europe's human potential. On 22 Decem...

  20. National and regional asthma programmes in Europe.

    Science.gov (United States)

    Selroos, Olof; Kupczyk, Maciej; Kuna, Piotr; Łacwik, Piotr; Bousquet, Jean; Brennan, David; Palkonen, Susanna; Contreras, Javier; FitzGerald, Mark; Hedlin, Gunilla; Johnston, Sebastian L; Louis, Renaud; Metcalf, Leanne; Walker, Samantha; Moreno-Galdó, Antonio; Papadopoulos, Nikolaos G; Rosado-Pinto, José; Powell, Pippa; Haahtela, Tari

    2015-09-01

    This review presents seven national asthma programmes to support the European Asthma Research and Innovation Partnership in developing strategies to reduce asthma mortality and morbidity across Europe. From published data it appears that in order to influence asthma care, national/regional asthma programmes are more effective than conventional treatment guidelines. An asthma programme should start with the universal commitments of stakeholders at all levels and the programme has to be endorsed by political and governmental bodies. When the national problems have been identified, the goals of the programme have to be clearly defined with measures to evaluate progress. An action plan has to be developed, including defined re-allocation of patients and existing resources, if necessary, between primary care and specialised healthcare units or hospital centres. Patients should be involved in guided self-management education and structured follow-up in relation to disease severity. The three evaluated programmes show that, thanks to rigorous efforts, it is possible to improve patients' quality of life and reduce hospitalisation, asthma mortality, sick leave and disability pensions. The direct and indirect costs, both for the individual patient and for society, can be significantly reduced. The results can form the basis for development of further programme activities in Europe. Copyright ©ERS 2015.

  1. National and regional asthma programmes in Europe

    Directory of Open Access Journals (Sweden)

    Olof Selroos

    2015-09-01

    Full Text Available This review presents seven national asthma programmes to support the European Asthma Research and Innovation Partnership in developing strategies to reduce asthma mortality and morbidity across Europe. From published data it appears that in order to influence asthma care, national/regional asthma programmes are more effective than conventional treatment guidelines. An asthma programme should start with the universal commitments of stakeholders at all levels and the programme has to be endorsed by political and governmental bodies. When the national problems have been identified, the goals of the programme have to be clearly defined with measures to evaluate progress. An action plan has to be developed, including defined re-allocation of patients and existing resources, if necessary, between primary care and specialised healthcare units or hospital centres. Patients should be involved in guided self-management education and structured follow-up in relation to disease severity. The three evaluated programmes show that, thanks to rigorous efforts, it is possible to improve patients' quality of life and reduce hospitalisation, asthma mortality, sick leave and disability pensions. The direct and indirect costs, both for the individual patient and for society, can be significantly reduced. The results can form the basis for development of further programme activities in Europe.

  2. The Gold Standard Programme

    DEFF Research Database (Denmark)

    Neumann, Tim; Rasmussen, Mette; Ghith, Nermin

    2013-01-01

    To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates.......To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates....

  3. Motivation programmes of organizations

    OpenAIRE

    Pízová, Tereza

    2008-01-01

    The Bachelor Thesis "'Motivation Programmes of Organizations" focuses on an extremely important area within personnel management. Employee motivation is crucial to the effective operation of businesses. Motivation programmes assist in increasing and maintaining employee motivation and demonstrate an organization's interest in its employees. This piece is on one hand concerned with theoretical foundations of motivation, describing theories and concepts important to the area of human behaviour ...

  4. Evaluating the effectiveness of a schools-based programme to promote exercise self-efficacy in children and young people with risk factors for obesity: Steps to active kids (STAK

    Directory of Open Access Journals (Sweden)

    Yang Min

    2011-10-01

    Full Text Available Abstract Background Low levels of physical activity in children have been linked to an increased risk of obesity, but many children lack confidence in relation to exercise (exercise self-efficacy. Factors which can impact on confidence include a chronic health condition such as asthma, poor motor skills and being overweight. Increasing levels of physical activity have obvious benefits for children with asthma and children who are overweight, but few activity interventions with children specifically target children with low exercise self-efficacy (ESE. This study aims to evaluate the efficacy and feasibility of a schools-based activity programme suitable for children with risk factors for adult obesity, including asthma, overweight and low exercise self-efficacy. Methods/Design A clustered (at the level of school RCT will be used to compare a targeted, 10 week, stepped activity programme (activity diary, dance DVD, circuit-training and motivational interviewing designed to promote ESE. We will recruit 20 primary schools to participate in the intervention and 9-11 year old children will be screened for low levels of ESE, asthma and overweight. In order to provide sufficient power to detect a difference in primary outcomes (Body Mass Index-BMI & ESE at 12 month follow-up between children in the intervention schools and control schools, the target sample size is 396. Assessments of BMI, ESE, waist circumference, peak flow, activity levels and emotional and behavioural difficulties will be made at baseline, 4 months and 12 month follow-up. Discussion We aim to increase ESE and levels of physical activity in children with risk factors for adult obesity. The outcomes of this study will inform policy makers about the feasibility, acceptability and effectiveness of delivering targeted health interventions within a school setting. Trial Registration ISRCTN Register no. ISRCTN12650001

  5. FUSION technology programme 2003-2006

    International Nuclear Information System (INIS)

    Karttunen, S.; Rantamaeki, K.

    2007-01-01

    This report summarises the results of the FUSION technology programme during the period between 2003-2006. FUSION is a continuation of the previous FFusion and FFusion2 technology programmes that took place from 1993 to 2002. The FUSION technology programme was fully integrated into the European Fusion Programme in the sixth Framework Programme (Euratom), through the bilateral Contract of Association between Euratom and Tekes and the multilateral European Fusion Development Agreement (EFDA). The Association Euratom-Tekes was established in 1995. At the moment, there are 26 Euratom Fusion associations working together as an European Research Area. There are four research areas in the FUSION technology programme: (1) fusion physics and plasma engineering, (2) vessel/in-vessel materials, joints and components, (3) in-vessel remote handling systems, and (4) system studies. The FUSION team consists of research groups from the Technical Research Centre of Finland (VTT), the Helsinki, Tampere and Lappeenranta Universities of Technology and the University of Helsinki. The co-ordinating unit is VTT. A key element of the FUSION programme is the close collaboration between VTT, the universities and the industry, which has resulted in dynamic and sufficiently large research teams to tackle challenging research and development projects. The distribution of work between research institutes and industry has also been clear. Industrial activities related to the FUSION programme are co-ordinated through the 'Big Science' Project by Finpro and Prizztech. The total expenditure of the FUSION technology programme for 2003-2006 amounted to euro 14,9 million in research work at VTT and the universities with an additional euro 3,5 million for projects by the Finnish companies including the industry co-ordination. The funding of the FUSION programme and related industrial projects was mainly provided by Tekes (37%), Euratom (38%) and the participating institutes and industry (24%). The

  6. Framework Programmable Platform for the Advanced Software Development Workstation (FPP/ASDW). Demonstration framework document. Volume 1: Concepts and activity descriptions

    Science.gov (United States)

    Mayer, Richard J.; Blinn, Thomas M.; Dewitte, Paul S.; Crump, John W.; Ackley, Keith A.

    1992-01-01

    The Framework Programmable Software Development Platform (FPP) is a project aimed at effectively combining tool and data integration mechanisms with a model of the software development process to provide an intelligent integrated software development environment. Guided by the model, this system development framework will take advantage of an integrated operating environment to automate effectively the management of the software development process so that costly mistakes during the development phase can be eliminated. The Advanced Software Development Workstation (ASDW) program is conducting research into development of advanced technologies for Computer Aided Software Engineering (CASE).

  7. An outline of IAEA programme for 1963

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1962-10-15

    Some of the important details of the programme are given. From the financial point of view the Agency's work is divided into two categories. The first comprises activities which fall under the Regular Budget and are financed out of assessed contributions by Member States, while the second consists of activities under the Operational Budget, financed out of voluntary contributions by Member States to the Agency's General Fund and other resources, such as funds made available under the United Nations Expanded Programme of Technical Assistance (EPTA) and gifts of equipment, free services of experts and free training facilities. Chief among the latter activities are technical assistance and training

  8. An outline of IAEA programme for 1963

    International Nuclear Information System (INIS)

    1962-01-01

    Some of the important details of the programme are given. From the financial point of view the Agency's work is divided into two categories. The first comprises activities which fall under the Regular Budget and are financed out of assessed contributions by Member States, while the second consists of activities under the Operational Budget, financed out of voluntary contributions by Member States to the Agency's General Fund and other resources, such as funds made available under the United Nations Expanded Programme of Technical Assistance (EPTA) and gifts of equipment, free services of experts and free training facilities. Chief among the latter activities are technical assistance and training

  9. Effects of pinealectomy on the neuroendocrine reproductive system and locomotor activity in male European sea bass, Dicentrarchus labrax.

    Science.gov (United States)

    Cowan, Mairi; Paullada-Salmerón, José A; López-Olmeda, José Fernando; Sánchez-Vázquez, Francisco Javier; Muñoz-Cueto, José A

    2017-05-01

    The seasonally changing photoperiod controls the timing of reproduction in most fish species, however, the transduction of this photoperiodic information to the reproductive axis is still unclear. This study explored the potential role of two candidate neuropeptide systems, gonadotropin-inhibitory hormone (Gnih) and kisspeptin, as mediators between the pineal organ (a principle transducer of photoperiodic information) and reproductive axis in male European sea bass, Dicentrarchus labrax. Two seven-day experiments of pinealectomy (Px) were performed, in March (end of reproductive season) and August (resting season). Effects of Px and season on the brain expression of gnih (sbgnih) and its receptor (sbgnihr), kisspeptins (kiss1, kiss2) and their receptors (kissr2, kissr3) and gonadotropin-releasing hormone (gnrh1, gnrh2, gnrh3) and the main brain receptor (gnrhr-II-2b) genes, plasma melatonin levels and locomotor activity rhythms were examined. Results showed that Px reduced night-time plasma melatonin levels. Gene expression analyses demonstrated a sensitivity of the Gnih system to Px in March, with a reduction in sbgnih in the mid-hindbrain, a region with bilateral connections to the pineal organ. In August, kiss2 levels increased in Px animals but not in controls. Significant differences in expression were observed for diencephalic sbgnih, sbgnihr, kissr3 and tegmental gnrh2 between seasons. Recordings of locomotor activity following surgery revealed a change from light-synchronised to free-running rhythmic behavior. Altogether, the Gnih and Kiss2 sensitivity to Px and seasonal differences observed for Gnih and its receptor, Gnrh2, and the receptor for Kiss2 (Kissr3), suggested they could be mediators involved in the relay between environment and seasonal reproduction. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. The 'Walking for Wellbeing in the West' randomised controlled trial of a pedometer-based walking programme in combination with physical activity consultation with 12 month follow-up: rationale and study design

    Directory of Open Access Journals (Sweden)

    Ogilvie David

    2008-07-01

    Full Text Available Abstract Background Scotland has a policy aimed at increasing physical activity levels in the population, but evidence on how to achieve this is still developing. Studies that focus on encouraging real world participants to start physical activity in their settings are needed. The Walking for Well-being in the West study was designed to assess the effectiveness of a pedometer-based walking programme in combination with physical activity consultation. The study was multi-disciplinary and based in the community. Walking for Well-being in the West investigated whether Scottish men and women, who were not achieving the current physical activity recommendation, increased and maintained walking behaviour over a 12 month period. This paper outlines the rationale and design of this innovative and pragmatic study. Methods Participants were randomised into two groups: Group 1: Intervention (pedometer-based walking programme combined with a series of physical activity consultations; Group 2: Waiting list control for 12 weeks (followed by minimal pedometer-based intervention. Physical activity (primary outcome was measured using pedometer step counts (7 day and the International Physical Activity Questionnaire (long version. Psychological processes were measured using questionnaires relating to the Transtheoretical Model of Behaviour Change, mood (Positive and Negative Affect Schedule and quality of life (Euroqol EQ-5D instrument. Physiological measures included anthropometric and metabolic outcomes. Environmental influences were assessed subjectively (Neighbourhood Quality of Life Survey and objectively (neighbourhood audit tool and GIS mapping. The qualitative evaluation employed observation, semi-structured interviews and focus groups. A supplementary study undertook an economic evaluation. Discussion Data analysis is on-going. Walking for Well-being in the West will demonstrate if a pedometer based walking programme, in combination with physical

  11. Status of national programmes on fast reactors

    International Nuclear Information System (INIS)

    1994-04-01

    Based on the International Working Group on Fast reactors (IWGFR) members' request, the IAEA organized a special meeting on Fast Reactor Development and the Role of the IAEA in May 1993. The purpose of the meeting was to review and discuss the status and recent development, to present major changes in fast reactor programmes and to recommend future activities on fast reactors. The IWGFR took note that in some Member States large prototypes have been built or are under construction. However, some countries, due to their current budget constraints, have reduced the level of funding for research and development programmes on fast reactors. The IWGFR noted that in this situation the international exchange of information and cooperation on the development of fast reactors is highly desirable and stressed the importance of the IAEA's programme on fast reactors. These proceedings contain important and useful information on national programmes and new developments in sodium cooled fast reactors in Member States. Refs, figs and tabs

  12. The UNESCO Bioethics Programme: a review.

    Science.gov (United States)

    Langlois, Adéle

    2014-01-01

    UNESCO's Bioethics Programme was established in 1993. In twenty years it has adopted three international declarations, on the human genome (1997), human genetic data (2003) and bioethics (2005); produced reports on a wide range of bioethics issues; and developed capacity building and public education programmes in bioethics. Yet UNESCO has sometimes struggled to assert its authority in the wider bioethics world. Some bioethicists have criticized the 2005 declaration and suggested that the World Health Organization might be better placed to advance bioethics. In 2011, after four years of debate, UNESCO decided not to draft a convention on human reproductive cloning, because consensus on the issue proved impossible. This article reviews the standard setting and capacity building activities of the UNESCO Bioethics Programme. While the Programme faces challenges common to most intergovernmental organizations, its achievements in expanding international law and building bioethics capacity should not be underestimated.

  13. IAEA programme on research reactor safety

    International Nuclear Information System (INIS)

    Alcala, F.; Di Meglio, A.F.

    1995-01-01

    This paper describes the IAEA programme on research reactor safety and includes the safety related areas of conversions to the use of low enriched uranium (LEU) fuel. The program is based on the IAEA statutory responsibilities as they apply to the requirements of over 320 research reactors operating around the world. The programme covers four major areas: (a) the development of safety documents; (b) safety missions to research reactor facilities; (c) support of research programmes on research reactor safety; (d) support of Technical Cooperation projects on research reactor safety issues. The demand for these activities by the IAEA member states has increased substantially in recent years especially in developing countries with increasing emphasis being placed on LEU conversion matters. In response to this demand, the IAEA has undertaken an extensive programme for each of the four areas above. (author)

  14. The CERN & Society programme launches its newsletter

    CERN Multimedia

    Matteo Castoldi

    2016-01-01

    The newsletter will be issued quarterly. Sign up to remain informed about the latest initiatives of the CERN & Society programme!    The CERN & Society programme encompasses projects in the areas of education and outreach, innovation and knowledge exchange, and culture and creativity that spread the CERN spirit of scientific curiosity for the inspiration and benefit of society. The programme is funded primarily by the CERN & Society Foundation, a charitable foundation established by CERN and supported by individuals, trusts, organisations and commercial companies. The projects are inspired or enabled by CERN but lie outside of the Laboratory’s specific research mandate. We especially want to help young talent from around the world to flourish in the future. The programme is now launching its newsletter, which will be issued quarterly. Everybody who wants to be informed about CERN & Society’s activities, stay up-to-date with its latest in...

  15. Status of national gas cooled reactor programmes

    International Nuclear Information System (INIS)

    1991-08-01

    This report has been compiled as a central source of summary-level information on the present status of High Temperature Gas-Cooled Reactor (HTGR) programmes in the world and on future plans for the continued development and deployment of HTGRs. Most of the information concerns the programmes in the United States, Germany, Japan and the Soviet Union, countries that have had large programmes related to HTGR technology for several years. Summary-level information is also provided in the report on HTGR-related activities in several other countries who either have an increasing interest in the technology and/or who are performing some development efforts related to HTGR technology. The report contains a summary-level update on the MAGNOX and AGR programmes. This is the twelfth issue of the document, the first of which was issued in March, 1979. The report has been prepared in the IAEA Nuclear Power Technology Development Section. Figs and tabs

  16. The INTEGRAL Core Observing Programme

    DEFF Research Database (Denmark)

    Winkler, C.; Gehrels, N.; Lund, Niels

    1999-01-01

    The Core Programme of the INTEGRAL mission is defined as the portion of the scientific programme covering the guaranteed time observations for the INTEGRAL Science Working Team. This paper describes the current status of the Core Programme preparations and summarizes the key elements...... of the observing programme....

  17. South African antarctic biological research programme

    CSIR Research Space (South Africa)

    SASCAR

    1981-07-01

    Full Text Available This document provides a description of the past, current and planned South African biological research activities in the sub-Antarctic and Antarctic regions. Future activities will fall under one of the five components of the research programme...

  18. The impact of active stakeholder involvement on recruitment, retention and engagement of schools, children and their families in the cluster randomised controlled trial of the Healthy Lifestyles Programme (HeLP): a school-based intervention to prevent obesity.

    Science.gov (United States)

    Lloyd, J; McHugh, C; Minton, J; Eke, H; Wyatt, K

    2017-08-14

    Recruitment and retention of participants is crucial for statistical power and internal and external validity and participant engagement is essential for behaviour change. However, many school-based interventions focus on programme content rather than the building of supportive relationships with all participants and tend to employ specific standalone strategies, such as incentives, to improve retention. We believe that actively involving stakeholders in both intervention and trial design improves recruitment and retention and increases the chances of creating an effective intervention. The Healthy Lifestyles Programme, HeLP (an obesity prevention programme for children 9-10 years old) was developed using intervention mapping and involved extensive stakeholder involvement in both the design of the trial and the intervention to ensure that: (i) delivery methods were suitably engaging, (ii) deliverers had the necessary skills and qualities to build relationships and (iii) the intervention dovetailed with the National Curriculum. HeLP was a year-long intervention consisting of 4 multi-component phases using a range of delivery methods. We recruited 1324 children from 32 schools from the South West of England to a cluster-randomised controlled trial to determine the effectiveness of HeLP in preventing obesity. The primary outcome was change in body mass index standard deviation score (BMI SDS) at 24 months post randomisation. Secondary outcomes included additional anthropometric and behavioural (physical activity and diet) measures at 18 and 24 months. Anthropometric and behavioural measures were taken in 99%, 96% and 94% of children at baseline, 18 and 24 months, respectively, with no differential follow up between the control and intervention groups at each time point. All children participated in the programme and 92% of children and 77% of parents across the socio-economic spectrum were considered to have actively engaged with HeLP. We attribute our excellent

  19. Double Kissing Crush Versus Provisional Stenting for Left Main Distal Bifurcation Lesions: DKCRUSH-V Randomized Trial.

    Science.gov (United States)

    Chen, Shao-Liang; Zhang, Jue-Jie; Han, Yaling; Kan, Jing; Chen, Lianglong; Qiu, Chunguang; Jiang, Tiemin; Tao, Ling; Zeng, Hesong; Li, Li; Xia, Yong; Gao, Chuanyu; Santoso, Teguh; Paiboon, Chootopol; Wang, Yan; Kwan, Tak W; Ye, Fei; Tian, Nailiang; Liu, Zhizhong; Lin, Song; Lu, Chengzhi; Wen, Shangyu; Hong, Lang; Zhang, Qi; Sheiban, Imad; Xu, Yawei; Wang, Lefeng; Rab, Tanveer S; Li, Zhanquan; Cheng, Guanchang; Cui, Lianqun; Leon, Martin B; Stone, Gregg W

    2017-11-28

    Provisional stenting (PS) is the most common technique used to treat distal left main (LM) bifurcation lesions in patients with unprotected LM coronary artery disease undergoing percutaneous coronary intervention. The double kissing (DK) crush planned 2-stent technique has been shown to improve clinical outcomes in non-LM bifurcations compared with PS, and in LM bifurcations compared with culotte stenting, but has never been compared with PS in LM bifurcation lesions. The authors sought to determine whether a planned DK crush 2-stent technique is superior to PS for patients with true distal LM bifurcation lesions. The authors randomized 482 patients from 26 centers in 5 countries with true distal LM bifurcation lesions (Medina 1,1,1 or 0,1,1) to PS (n = 242) or DK crush stenting (n = 240). The primary endpoint was the 1-year composite rate of target lesion failure (TLF): cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization. Routine 13-month angiographic follow-up was scheduled after ascertainment of the primary endpoint. TLF within 1 year occurred in 26 patients (10.7%) assigned to PS, and in 12 patients (5.0%) assigned to DK crush (hazard ratio: 0.42; 95% confidence interval: 0.21 to 0.85; p = 0.02). Compared with PS, DK crush also resulted in lower rates of target vessel myocardial infarction I (2.9% vs. 0.4%; p = 0.03) and definite or probable stent thrombosis (3.3% vs. 0.4%; p = 0.02). Clinically driven target lesion revascularization (7.9% vs. 3.8%; p = 0.06) and angiographic restenosis within the LM complex (14.6% vs. 7.1%; p = 0.10) also tended to be less frequent with DK crush compared with PS. There was no significant difference in cardiac death between the groups. In the present multicenter randomized trial, percutaneous coronary intervention of true distal LM bifurcation lesions using a planned DK crush 2-stent strategy resulted in a lower rate of TLF at 1 year than a PS

  20. A process evaluation of a supervisory development programme

    Directory of Open Access Journals (Sweden)

    Jasper Buys

    2012-07-01

    Research purpose: The study aimed to provide information about coverage, service delivery, organisational resources, and medium-term outcomes for a supervisory development programme (SDP in the hospitality industry. Motivation for the study: The primary motivation was to assist programme staff to understand their programme and also to generate information that the programme staff could use to reflect on the programme’s performance and future direction. Research design, approach and method: A mixture of quantitative and qualitative methods was employed, namely: a literature review; personal interviews; and internal programme documentation, such as e-mail correspondence, financial statements, attendance registers, and personnel records. Personal interviews were conducted with two stakeholders, namely the programme manager and programme administrator. The programme data of 69 participants in the SDP were utilised for the evaluation. Main findings: The evaluation’s main finding concluded that the ‘implemented programme’ was not congruent with the ‘planned programme’. Practical/managerial implications: It is recommended that programme activities and theory should be re-evaluated, as the programme is used mainly as a training programme for new appointees, rather than a management development programme to create a pool of potential supervisors. Programme uptake and output should also be closely aligned. The length of time that people in the pool of potential supervisors had to wait before they were appointed should also be reduced. Contribution/value-add: By explicating the basic programme theory and studying programme implementation, this evaluation serves as a starting point for future evaluations of the SDP.

  1. Programmable Automated Welding System (PAWS)

    Science.gov (United States)

    Kline, Martin D.

    1994-01-01

    An ambitious project to develop an advanced, automated welding system is being funded as part of the Navy Joining Center with Babcock & Wilcox as the prime integrator. This program, the Programmable Automated Welding System (PAWS), involves the integration of both planning and real-time control activities. Planning functions include the development of a graphical decision support system within a standard, portable environment. Real-time control functions include the development of a modular, intelligent, real-time control system and the integration of a number of welding process sensors. This paper presents each of these components of the PAWS and discusses how they can be utilized to automate the welding operation.

  2. The French nuclear programme

    International Nuclear Information System (INIS)

    Feger, M.

    1990-01-01

    EDF has long been interested in the use of nuclear energy for thermal power generation. After a period of apprenticeship and experiments, EDF launched a major PWR plant programme so as to reduce France's energy dependence and master generation costs. This programme, based on standardization, has achieved the desired results. It must now be adapted to suit the needs of the 21st century. For this programme, all those involved (Governmental authorities, EDF, manufacturers) were mobilized to an unprecedented extent and rigorous working methods were imposed. Experience feedback has been used to make improvements both to the installations themselves and to procedures. Results have proved satisfactory as regards nuclear safety but vigilance must be maintained. Public opinion on nuclear power is reserved we are sentenced to achieving a 'fault-free' track record, all the while mastering costs, so as to ensure the continuing use of nuclear energy. (author)

  3. The French nuclear programme

    Energy Technology Data Exchange (ETDEWEB)

    Feger, M [Ecole Nationale Superieure d' Electrotechnique de Grenoble, Institute National des Sciences et Techniques Nucleaires (Saclay), Gif-sur-Yvette, Electricite de France (France)

    1990-06-01

    EDF has long been interested in the use of nuclear energy for thermal power generation. After a period of apprenticeship and experiments, EDF launched a major PWR plant programme so as to reduce France's energy dependence and master generation costs. This programme, based on standardization, has achieved the desired results. It must now be adapted to suit the needs of the 21st century. For this programme, all those involved (Governmental authorities, EDF, manufacturers) were mobilized to an unprecedented extent and rigorous working methods were imposed. Experience feedback has been used to make improvements both to the installations themselves and to procedures. Results have proved satisfactory as regards nuclear safety but vigilance must be maintained. Public opinion on nuclear power is reserved we are sentenced to achieving a 'fault-free' track record, all the while mastering costs, so as to ensure the continuing use of nuclear energy. (author)

  4. External Mobility Programme

    CERN Multimedia

    HR Department

    2007-01-01

    Every year, a significant number of highly-skilled staff members leave the Organization and offer their talents on the European job market. CERN is launching a programme aiming to help staff members to whom the Organization cannot offer an indefinite contract in the transition towards their next employment. The programme, which is based on the establishment of a number of partnerships with potential employers in the private sector, will run on a voluntary basis. Staff members who have received confirmation that they will not be offered an indefinite contract and who are interested in availing themselves of the opportunities offered by the programme, are invited to enrol by following the procedure described at: https://ert.cern.ch/browse_intranet/wd_pds?p_web_page_id=5841 Applications will be processed in the strictest confidence by the Human Resources Department and eligible profiles will then be made available to partner companies for recruitment purposes. Any subsequent ...

  5. [Programmes against depression].

    Science.gov (United States)

    Taleb, M; Rouillon, F; Hegerl, U; Hamdani, N; Gorwood, Ph

    2006-01-01

    frequently criticized, as this may reduce efficacy. A multilevel approach is crucial for the success of action programmes against depression, because synergistic effects can be expected. In Germany, the "Nürnberger Bündnis gegen Depression" project was based on four levels, and effectively reduced the suicide rate. These levels of action included "cooperation with GPs", such as training sessions based on video, and presence of a phone hotline, "public relations activities", "training sessions for multipliers", such as priests, social workers and media, and "special offers for high risk groups and self-help activities". In France, such a program is clearly required.

  6. Finnish Fusion Research Programme Yearbook 1993-1994

    International Nuclear Information System (INIS)

    Karttunen, S.; Paettikangas, T.

    1995-05-01

    Finnish Fusion Research Programme (FFUSION) is one of the national energy research programmes funded by the Ministry of Trade and Industry and from 1995 by TEKES. National organization for fusion research is necessary for efficient and successful participation in international fusion programmes. FFUSION programme serves well for this purpose and it made possible to establish relations and the dialogue with the European Fusion Programme. The process led to the Finnish Association Euratom-TEKES in early 1995. The first period of the FFUSION programme (1993-1994) was preparation for the association to the Community Programme. The strategy was to emphasize fusion technology parallel with the basic fusion and plasma physics and to activate the related Finnish industry to collaborate and participate in the FFUSION programme and later in the European Fusion Programme. The key element in the strategy is the focusing our fairly small R and D effort to a few topics, which increases possibilities to be competitive in Europe. The physics programme in FFUSION deals mainly with theoretical and computational studies of radio-frequency heating in tokamak plasmas. Technology programme started with prestudies in 1993 and it concentrates into two areas: fusion reactor materials and remote handling systems. (8 figs., 3 tabs.)

  7. Probabilistic programmable quantum processors

    International Nuclear Information System (INIS)

    Buzek, V.; Ziman, M.; Hillery, M.

    2004-01-01

    We analyze how to improve performance of probabilistic programmable quantum processors. We show how the probability of success of the probabilistic processor can be enhanced by using the processor in loops. In addition, we show that an arbitrary SU(2) transformations of qubits can be encoded in program state of a universal programmable probabilistic quantum processor. The probability of success of this processor can be enhanced by a systematic correction of errors via conditional loops. Finally, we show that all our results can be generalized also for qudits. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  8. A programme in transition

    International Nuclear Information System (INIS)

    Dean, S.O.

    1992-01-01

    Fusion is beginning its transition from a scientific research programme to that of an engineering development programme aimed at practical applications. This transition is likely to last a decade or more because many scientific questions remain and because of the magnitude and cost of the engineering issues. This article reviews briefly the encouraging results produced at the Joint European Torus (JET) where 1.7 MW of fusion power was generated for 2 seconds in experiments in November 1991, the remaining scientific issues, the role of near-term experimental reactors like the International Thermonuclear Experimental reactor (ITER) and other approaches to a demonstration power plant. (author)

  9. Computer mathematics for programmers

    CERN Document Server

    Abney, Darrell H; Sibrel, Donald W

    1985-01-01

    Computer Mathematics for Programmers presents the Mathematics that is essential to the computer programmer.The book is comprised of 10 chapters. The first chapter introduces several computer number systems. Chapter 2 shows how to perform arithmetic operations using the number systems introduced in Chapter 1. The third chapter covers the way numbers are stored in computers, how the computer performs arithmetic on real numbers and integers, and how round-off errors are generated in computer programs. Chapter 4 details the use of algorithms and flowcharting as problem-solving tools for computer p

  10. Determination of 13C CSA Tensors: Extension of the Model-independent Approach to an RNA Kissing Complex Undergoing Anisotropic Rotational Diffusion in Solution

    International Nuclear Information System (INIS)

    Ravindranathan, Sapna; Kim, Chul-Hyun; Bodenhausen, Geoffrey

    2005-01-01

    Chemical shift anisotropy (CSA) tensor parameters have been determined for the protonated carbons of the purine bases in an RNA kissing complex in solution by extending the model-independent approach [Fushman, D., Cowburn, D. (1998) J. Am. Chem. Soc. 120, 7109-7110]. A strategy for determining CSA tensor parameters of heteronuclei in isolated X-H two-spin systems (X = 13 C or 15 N) in molecules undergoing anisotropic rotational diffusion is presented. The original method relies on the fact that the ratio κ 2 =R 2 auto /R 2 cross of the transverse auto- and cross-correlated relaxation rates involving the X CSA and the X-H dipolar interaction is independent of parameters related to molecular motion, provided rotational diffusion is isotropic. However, if the overall motion is anisotropic κ 2 depends on the anisotropy D parallel /D -perpendicular of rotational diffusion. In this paper, the field dependence of both κ 2 and its longitudinal counterpart κ 1 =R 1 auto /R 1 cross are determined. For anisotropic rotational diffusion, our calculations show that the average κ av = 1/2 (κ 1 +κ 2 ), of the ratios is largely independent of the anisotropy parameter D parallel /D -perpendicular . The field dependence of the average ratio κ av may thus be utilized to determine CSA tensor parameters by a generalized model-independent approach in the case of molecules with an overall motion described by an axially symmetric rotational diffusion tensor

  11. Mechanisms of Disease: the first kiss-a crucial role for kisspeptin-1 and its receptor, G-protein-coupled receptor 54, in puberty and reproduction.

    Science.gov (United States)

    Seminara, Stephanie B

    2006-06-01

    Although the hypothalamic secretion of gonadotropin-releasing hormone (GnRH) is the defining hormonal event of puberty, the physiologic mechanisms that drive secretion of GnRH at the time of sexual maturation have been difficult to identify. After puberty is initiated, the factors that modulate the frequency and amplitude of GnRH secretion in rapidly changing sex-steroid environments (i.e. the female menstrual cycle) also remain unknown. The discovery that, in both humans and mouse models, loss-of-function mutations in the gene that encodes G-protein-coupled receptor 54 result in phenotypes of hypogonadotropic hypogonadism with an absence of pubertal development has unearthed a novel pathway regulating GnRH secretion. Ligands for G-protein-coupled receptor 54 (KiSS-1R), including metastin (derived from the parent compound, kisspeptin-1) and metastin's C-terminal peptide fragments, have been shown to be powerful stimulants for GnRH release in vivo via their stimulation of G-protein-coupled receptor 54. This article reviews the discovery of the GPR54 gene, places it into the appropriate biological context, and explores the data from in vitro and in vivo studies that point to this ligand-receptor system as a major driver of GnRH secretion.

  12. A reappraisal of the virtues of private sector employment programmes

    DEFF Research Database (Denmark)

    Jensen, Peter; Graversen, Brian Krogh

    In this paper, we evaluate the employment effects of Danish active labour market programmes aimed at welfare benefit recipients. We estimate an econometric model with treatment effects and discrete outcomes and we allow the responses to treatment to vary among observationally identical persons. T...... significant mean effects of participation in private sector employment programmes compared to participation in other programmes, but we find evidence of heterogeneity in the treatment effects....

  13. Mexican medfly programme

    International Nuclear Information System (INIS)

    1980-01-01

    This film tells the story of the fight against and final extinction of the Mediterranean fruit-fly (Ceratitis capitata) in Mexico. By producing billions of high quality sterile flies in the Medfly reproduction and sterilization laboratory in the province of Chiapas and releasing them over infested areas, the Moscamed Programme succeeded in eradicating this pest from Mexico in 1982

  14. Nuclear safety. Improvement programme

    International Nuclear Information System (INIS)

    2000-01-01

    In this brochure the improvement programme of nuclear safety of the Mochovce NPP is presented in detail. In 1996, a 'Mochovce NPP Nuclear Safety Improvement Programme' was developed in the frame of unit 1 and 2 completion project. The programme has been compiled as a continuous one, with the aim to reach the highest possible safety level at the time of commissioning and to establish good preconditions for permanent safety improvement in future. Such an approach is in compliance with the world's trends of safety improvement, life-time extension, modernisation and nuclear station power increase. The basic document for development of the 'Programme' is the one titled 'Safety Issues and their Ranking for WWER 440/213 NPP' developed by a group of IAEA experts. The following organisations were selected for solution of the safety measures: EUCOM (Consortium of FRAMATOME, France, and SIEMENS, Germany); SKODA Prague, a.s.; ENERGOPROJEKT Prague, a.s. (EGP); Russian organisations associated in ATOMENERGOEXPORT; VUJE Trnava, a.s

  15. Progressive Retirement Programme

    CERN Document Server

    HR Department

    2009-01-01

    Following the Standing Concertation Committee meeting of 2 December 2008, please note that the Progressive Retirement Programme has been extended by one year, i.e. until 31 March 2010. Further information is available on : https://hr-services.web.cern.ch/hr-services/services-Ben/prp/prp.asp HR Department, tel. 73903

  16. Programmable dc motor controller

    Science.gov (United States)

    Hopwood, J. E.

    1982-11-01

    A portable programmable dc motor controller, with features not available on commercial instruments was developed for controlling fixtures during welding processes. The controller can be used to drive any dc motor having tachometer feedback and motor requirements not exceeding 30 volts, 3 amperes. Among the controller's features are delayed start time, upslope time, speed, and downslope time.

  17. Air Quality Monitoring Programme

    DEFF Research Database (Denmark)

    Kemp, K.; Palmgren, F.

    The Danish Air Quality Monitoring Programme (LMP IV) has been revised in accordance with the Framework Directive and the first three daughter directives of SO2, NOx/NO2, PM10, lead, benzene, CO and ozone. PM10 samplers are under installation and the installation will be completed during 2002...

  18. The European Programme Manager

    DEFF Research Database (Denmark)

    Larson, Anne; Bergman, E.; Ehlers, S.

    The publication is a result of a cooperation between organisations in six European countries with the aim to develop a common European education for programme managers. It contains of a description of the different elements of the education together with a number of case-studies from the counties...

  19. The Productive Programmer

    CERN Document Server

    Ford, Neal

    2009-01-01

    Anyone who develops software for a living needs a proven way to produce it better, faster, and cheaper. The Productive Programmer offers critical timesaving and productivity tools that you can adopt right away, no matter what platform you use. Master developer Neal Ford details ten valuable practices that will help you elude common traps, improve your code, and become more valuable to your team.

  20. A special evaluation: The ARCAL programme

    International Nuclear Information System (INIS)

    1992-01-01

    The Regional Co-operative Arrangements for the Promotion of Nuclear Science and Technology in Latin America, ARCAL, came into being in 1983. At a meeting held in Vienna in September 1984, ten Latin American countries agreed to participate in the programme, the Guidelines setting up the structure of the programme were approved and nine areas of development were identified to initiate project activities. The programme, which is now in its second phase and in its ninth year of implementation, has 17 Member States and includes fifteen projects. Total disbursements under the ARCAL programme during the period 1983 - 1991 amounted to $8.5 million, including $5.4 million from the Technical Assistance and Co-operation Fund (TACF), $2.2 million from extrabudgetary sources, and some $0.9 million in the form of in-kind contributions. As of September 1992, equipment totaling $3.5 million, 385 man-months of expert services, and 108 fellowships for approximately 150 man-months of training had been provided to ARCAL Member States within the context of fifteen ARCAL projects. In addition, 1844 Latin Americans were trained in 194 ARCAL training courses. The evaluation concluded that, as a result of the ARCAL programme, there is now better knowledge in participating countries about nuclear techniques and technology, as well as greater awareness at most levels of the importance of radiological safety and of the need to implement radiation protection measures, both a the national and at the regional level. The programme has contributed to developing and/or improving capabilities in the region in various applications of nuclear techniques through training activities. The programme has further allowed the establishment of regional collaborative links, particularly between countries with similar interests, in important fields of application, such as agriculture and nuclear medicine. Figs and tabs

  1. Activities of the Bloomberg Philanthropies Global Road Safety Programme (formerly RS10) in Russia: promising results from a sub-national project.

    Science.gov (United States)

    Slyunkina, Ekaterina S; Kliavin, Vladimir E; Gritsenko, Elena A; Petruhin, Alexandr B; Zambon, Francesco; He, Huan; Hyder, Adnan A

    2013-12-01

    In Russia, the high Road Traffic Injuries (RTIs) rate has been attributed to two well-known risk factors - the low rates of seatbelt and child restraints use and speeding. Despite the importance of understanding both speeding and seatbelt use patterns for the purpose of direct interventions or monitoring road safety situation, no study has assessed the current status of speeding among all vehicles and seatbelt wearing rates among all vehicle occupants in Russia. We are aware that alcohol is a known risk factor for RTI in the country however the work focused on seat belts and speed. This research was conducted as part of the Bloomberg Philanthropies Global Road Safety Programme and focuses on observed speeding and seatbelt use in two Russian regions: Lipetskaya and Ivanovskaya Oblast. Data was collected through observational surveys on selected roads in the two interventions sites (Lipetskaya and Ivanovskaya Oblast) between October 2010 and March 2013. The percentage of seatbelt use by drivers and passengers and the percentage of speeding vehicles by speed limit and road types were calculated. Observational studies on speeding show signs that drivers are speeding less from the first survey held in July 2011 in Lipetskaya Oblast and March 2012 in Ivanovksya Oblast. Overall the observational studies showed a consistent reduction in the proportion of vehicles exceeding the speed limit: from 54.7% (2012) to 40.1% (2013) in Ivanovskaya Oblast and from 47.0% (2011) to 26.1% (2013) in Lipetskaya Oblast. Observational studies on seatbelt use demonstrate an increase in seatbelt wearing rates from the first survey held in October 2010 in Lipetskaya Oblast and April 2011 in Ivanovskaya Oblast. The overall prevalence of seatbelt use increased from 52.4% (2010) to 73.5% (2013) amongst all occupants in Lipetskaya Oblast and from 47.5% (2011) to 88.8% (2013) in Ivanovskaya Oblast. Preliminary results show some promising signs that speeding and seatbelt use are moving in the right

  2. Donor transplant programme

    International Nuclear Information System (INIS)

    Abu Bakar Sulaiman

    1999-01-01

    The transplantation of organs and tissues from one human to another human has become an essential and well established form of therapy for many types of organ and tissue failure. In Malaysia, kidney, cornea and bone marrow transplantation are well established. Recently, liver, bone and heart transplanation have been performed. Unfortunately, because of the lack of cadaveric organ donation, only a limited number of solid organ transplantation have been performed. The cadaveric organ donor rate in Malaysia is low at less than one per million population. The first tissue transplanted in Malaysia was the cornea which was performed in the early 1970s. At that time and even now the majority of corneas came from Sri Lanka. The first kidney transplant was performed in 1975 from a live related donor. The majority of the 629 kidney transplants done at Hospital Kuala Lumpur to date have been from live related donors. Only 35 were from cadaver donors. Similarly, the liver transplantation programme which started in 1995 are from live related donors. A more concerted effort has been made recently to increase the awareness of the public and the health professionals on organ and tissue donation. This national effort to promote organ and tissue donation seems to have gathered momentum in 1997 with the first heart transplant successfully performed at the National Heart Institute. The rate of cadaveric donors has also increased from a previous average of I to 2 per year to 6 per year in the last one year. These developments are most encouraging and may signal the coming of age of our transplantati on programme. The Ministry of Health in conjunction with various institutions, organizations and professional groups, have taken a number of proactive measures to facilitate the development of the cadaveric organ donation programme. Efforts to increase public awareness and to overcome the negative cultural attitude towards organ donation have been intensified. Equally important are efforts

  3. Climate Ambassador Programmes in Municipalities

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Pedersen, Stine Rahbek

    2016-01-01

    Some Danish municipalities have developed ambassador programmes which generate environmental and climate change mitigation efforts in local public administrations and institutions. This chapter analyses the characteristics and experiences of four ambassador programmes now operating...

  4. Mammographic screening programmes in Europe

    DEFF Research Database (Denmark)

    Giordano, Livia; von Karsa, Lawrence; Tomatis, Mariano

    2012-01-01

    To summarize participation and coverage rates in population mammographic screening programmes for breast cancer in Europe.......To summarize participation and coverage rates in population mammographic screening programmes for breast cancer in Europe....

  5. Italian programme to optimise X-ray diagnostic exposure

    International Nuclear Information System (INIS)

    Susanna, A.; Fioratti, M.P.

    1985-01-01

    Scientific associations in Italy such as the Assoziazione Italiana di Radioprotezione (AIRP), the Societa Italiana di Biologia e Medicina Nucleare (SIBMN) and the Assoziazione Italiana di Radiologia Medica e Medicina Nucleare (SIRMN) have been working on the problem of patient radiation protection for many years; their latest activities are described. Principal features and aims of the NEXT programme and the programme ''Dose and quality image in mammography'' will follow. Local administrations and Health Physics Services are involved in programmes on Genetically Significant Dose (GSD) evaluation or quality assurance: examples of these programmes are shown. Lastly, problems related to the education of radiological operators and radiologists are dealt with. (author)

  6. The TELEMAN programme

    International Nuclear Information System (INIS)

    Nordwall, H.J. de

    1990-01-01

    The TELEMAN programme is a five year cost-shared research programme covering remote handling in hazardous and disordered nuclear environments. TELEMAN's objective is to strengthen the scientific and engineering bases upon which the design of teleoperators for use throughout the nuclear industry rests. This will be done by providing new solutions to problems of manipulation, material transport and mobile surveillance in nuclear environments and by demonstrating their feasibility. The Commission's motivations lie in the potential teleoperators have to improve the separation of workers from radioactive equipment. The same technology will also enable plant operators and public authorities to deal more effectively with nuclear accidents. Finally, gains in productivity, particularly in the repair and maintenance area can be expected. Community support is justified by the cost of the reliability and autonomy required for the nuclear teleoperator, the need to rationalise R and D investment in an area of increasing industrial potential and a common interest in coherent responses to emergencies. (author)

  7. Fusion technology programme

    International Nuclear Information System (INIS)

    Finken, D.

    1984-10-01

    The KfK-Association has continued work on 17 R and D contracts of the Fusion Technology Programme. An effort of 94 manyears per year is at present contributed by 10 KfK departments, covering all aereas defined in the Fusion Technology Programme. The dominant part of the work is directed towards the need of the NET design or supporting experiments. Some additional effort addresses long term technological issues and system studies relevant to DEMO or confinement schemes alternative to tokamaks. Direct contribution to the NET team has increased by augmentation of NET study contracts and delegation of personnel, three KfK delegates being at present members of the NET team. In reverse, specifications and design guidelines worked out by NET have started to have an impact on the current R and D-work in the laboratory. (orig./GG)

  8. A programmable artificial retina

    International Nuclear Information System (INIS)

    Bernard, T.M.; Zavidovique, B.Y.; Devos, F.J.

    1993-01-01

    An artificial retina is a device that intimately associates an imager with processing facilities on a monolithic circuit. Yet, except for simple environments and applications, analog hardware will not suffice to process and compact the raw image flow from the photosensitive array. To solve this output problem, an on-chip array of bare Boolean processors with halftoning facilities might be used, providing versatility from programmability. By setting the pixel memory size to 3 b, the authors have demonstrated both the technological practicality and the computational efficiency of this programmable Boolean retina concept. Using semi-static shifting structures together with some interaction circuitry, a minimal retina Boolean processor can be built with less than 30 transistors and controlled by as few as 6 global clock signals. The successful design, integration, and test of such a 65x76 Boolean retina on a 50-mm 2 CMOS 2-μm circuit are presented

  9. The Brazilian nuclear programme

    International Nuclear Information System (INIS)

    Forman, J.M.A.

    1990-01-01

    Developing an energy policy for a country the size of Brazil is a formidable task. Large differences between the regions in geography and economic development do not allow for a uniform plan. In the mid 1970s, Brazil started a nuclear energy programme to provide it with another option in its energy planning. The objective of the programme was gradually to build a technical and industrial base for nuclear power in the country, so that it would be available when it was needed. It was recognized that it would not be easy for a developing country to acquire the necessary high technology. The organization of the industry is outlined, demand projections are presented and domestic supplies of uranium assessed. (author)

  10. The VIDA programme

    DEFF Research Database (Denmark)

    Jensen, Bente; Iannone, Rosa Lisa

    and Innovation’ within the project ‘Curriculum Quality Analysis and Impact Review of European Education and Care’ (CARE). The programme at the centre of this case builds on theory drawn from research on child development, social disadvantage related to issues of social inequality, and research on organisational...... of innovation as “the development of new concepts, strategies and tools that support groups in achieving the objective of improved well-being”. Three research questions are explored: 1) How is the innovative approach to ECEC professional development conceptualised and translated into practice in the VIDA...... (mechanisms/aspects) affect the implementation of the innovative programme for practice change within ECEC? Methods used include a combination of qualitative data collected through interviews with ECEC educators, managers, consultants, a university college teachers, municipal directors and existing...

  11. Pre- and post-intervention assessment of a PMTCT-programme ...

    African Journals Online (AJOL)

    PMTCT) services following implementation of programme-strengthening activities in a ... Keywords: antenatal care, health service delivery, HIV/AIDS, maternal health services, postnatal care, programme evaluation, quantitative research, women

  12. Programmable synchronous communications module

    International Nuclear Information System (INIS)

    Horelick, D.

    1979-10-01

    The functional characteristics of a programmable, synchronous serial communications CAMAC module with buffering in block format are described. Both bit and byte oriented protocols can be handled in full duplex depending on the program implemented. The main elements of the module are a Signetics 2652 Multi-Protocol Communications Controller, a Zilog Z-808 8 bit microprocessor with PROM and RAM, and FIFOs for buffering

  13. Programmable waveform controller

    International Nuclear Information System (INIS)

    Yeh, H.T.

    1979-01-01

    A programmable waveform controller (PWC) was developed for voltage waveform generation in the laboratory. It is based on the Intel 8080 family of chips. The hardware uses the modular board approach, sharing a common 44-pin bus. The software contains two separate programs: the first generates a single connected linear ramp waveform and is capable of bipolar operation, linear interpolation between input data points, extended time range, and cycling; the second generates four independent square waveforms with variable duration and amplitude

  14. The Mathematica programmer

    CERN Document Server

    Maeder, Roman E

    1994-01-01

    The Mathematica Programmer covers the fundamental programming paradigms and applications of programming languages. This book is organized into two parts encompassing 10 chapters. Part 1 begins with an overview of the programming paradigms. This part also treats abstract data types, polymorphism and message passing, object-oriented programming, and relational databases. Part 2 looks into the practical aspects of programming languages, including in lists and power series, fractal curves, and minimal surfaces.This book will prove useful to mathematicians and computer scientists.

  15. The Italian hydrogen programme

    International Nuclear Information System (INIS)

    Raffaele Vellone

    2001-01-01

    Hydrogen could become an important option in the new millennium. It provides the potential for a sustainable energy system as it can be used to meet most energy needs without harming the environment. In fact, hydrogen has the potential for contributing to the reduction of climate-changing emissions and other air pollutants as it exhibits clean combustion with no carbon or sulphur oxide emissions and very low nitrogen oxide emissions. Furthermore, it is capable of direct conversion to electricity in systems such as fuel cells without generating pollution. However, widespread use of hydrogen is not feasible today because of economic and technological barriers. In Italy, there is an ongoing national programme to facilitate the introduction of hydrogen as an energy carrier. This programme aims to promote, in an organic frame, a series of actions regarding the whole hydrogen cycle. It foresees the development of technologies in the areas of production, storage, transport and utilisation. Research addresses the development of technologies for separation and sequestration of CO 2 , The programme is shared by public organisations (research institutions and universities) and national industry (oil companies, electric and gas utilities and research institutions). Hydrogen can be used as a fuel, with significant advantages, both for electric energy generation/ co-generation (thermo-dynamic cycles and fuel cells) and transportation (internal combustion engine and fuel cells). One focus of research will be the development of fuel cell technologies. Fuel cells possess all necessary characteristics to be a key technology in a future economy based on hydrogen. During the initial phase of the project, hydrogen will be derived from fossil sources (natural gas), and in the second phase it will be generated from renewable electricity or nuclear energy. The presentation will provide a review of the hydrogen programme and highlight future goals. (author)

  16. Economic viability of new launched school lunch programmes

    DEFF Research Database (Denmark)

    Jensen, Jørgen Dejgård; Smed, Sinne; Mørkbak, Morten Raun

    2013-01-01

    activities related to the schools’ support and the users’ feeling of ownership, as well as internal professionalism and leadership in the implementation of the school lunch programme are important for the viability of the programme. Strong performance on the latter factors might to some extent compensate...

  17. All-Girls Adventure Programmes: What Are the Benefits?

    Science.gov (United States)

    Whittington, Anja; Mack, Erica Nixon; Budbill, Nadine W.; McKenney, Priscilla

    2011-01-01

    This study examined the benefits of all-girls adventure programmes from the perspective of adolescent girls. Participants included 361 girls aged 10-17 years from diverse ethnic and socio-economic backgrounds who completed a variety of adventure programmes. Adventure activities included rock climbing, sea kayaking, mountaineering, backpacking,…

  18. IAEA education and training programme in nuclear safety

    International Nuclear Information System (INIS)

    Bastos, J.L.F.; Lederman, L.

    2003-01-01

    This paper presents the IAEA education and training (E and T) programme in nuclear safety. A strategic planning for the programme implementation is described in terms of objectives, outputs and activities. A framework based on areas of competency and the level of depth of the training is presented as well as the main achievements to date. (author)

  19. The mass miniature chest radiography programme in Cape Town ...

    African Journals Online (AJOL)

    Background. Tuberculosis (TB) control programmes rely mainly on passive detection of symptomatic individuals. The resurgence of TB has rekindled interest in active case finding. Cape Town (South Africa) had a mass miniature radiography (MMR) screening programme from 1948 to 1994. Objective. To evaluate screening ...

  20. Effects of an exercise programme with people living with HIV ...

    African Journals Online (AJOL)

    Effects of an exercise programme with people living with HIV: research in a disadvantaged setting. Clemens Ley, Lloyd Leach, María Rato Barrio, Susan Bassett. Abstract. This study aimed to analyse the physical health effects of a community based 10-week physical activity programme with people living with HIV.

  1. Applying Student Team Achievement Divisions (STAD) Model on Material of Basic Programme Branch Control Structure to Increase Activity and Student Result

    Science.gov (United States)

    Akhrian Syahidi, Aulia; Asyikin, Arifin Noor; Asy’ari

    2018-04-01

    Based on my experience of teaching the material of branch control structure, it is found that the condition of the students is less active causing the low activity of the students on the attitude assessment during the learning process on the material of the branch control structure i.e. 2 students 6.45% percentage of good activity and 29 students percentage 93.55% enough and less activity. Then from the low activity resulted in low student learning outcomes based on a daily re-examination of branch control material, only 8 students 26% percentage reached KKM and 23 students 74% percent did not reach KKM. The purpose of this research is to increase the activity and learning outcomes of students of class X TKJ B SMK Muhammadiyah 1 Banjarmasin after applying STAD type cooperative learning model on the material of branch control structure. The research method used is Classroom Action Research. The study was conducted two cycles with six meetings. The subjects of this study were students of class X TKJ B with a total of 31 students consisting of 23 men and 8 women. The object of this study is the activity and student learning outcomes. Data collection techniques used are test and observation techniques. Data analysis technique used is a percentage and mean. The results of this study indicate that: an increase in activity and learning outcomes of students on the basic programming learning material branch control structure after applying STAD type cooperative learning model.

  2. An activity stimulation programme during a child's first year reduces some indicators of adiposity at the age of two-and-a-half

    NARCIS (Netherlands)

    de Vries, Agm; Huiting, H. G.; van den Heuvel, Er; L'Abée, C; Corpeleijn, E; Stolk, Rp

    AIM: Obesity tracks from childhood into adulthood. We evaluated the effect of early stimulation of physical activity on growth, body composition, motor activity and motor development in toddlers. METHODS: We performed a cluster randomised controlled single-blinded trial in Dutch Well Baby Clinics,

  3. An activity stimulation programme during a child's first year reduces some indicators of adiposity at the age of two-and-a-half

    NARCIS (Netherlands)

    Vries, de A.G.M.; Huiting, H.G.; Heuvel, van den E.R.; L'Abee, C.; Corpeleijn, E.; Stolk, R.P.

    2015-01-01

    Aim. Obesity tracks from childhood into adulthood. We evaluated the effect of early stimulation of physical activity on growth, body composition, motor activity and motor development in toddlers. Methods. We performed a cluster randomised controlled single-blinded trial in Dutch Well Baby Clinics,

  4. The Spanish radioactive waste management programme

    International Nuclear Information System (INIS)

    Beceiro, A.R.

    1994-01-01

    All radioactive waste management activities in Spain are controlled by the Empresa Nacional de Residuos Radiactivos, installed by royal decree in 1984. The programme for low- and intermediate-level wastes is well advanced. A near-surface repository for these type of wastes has been in operation since October 1992. The programme for high-level wastes including spent fuel from the operating nuclear power plants is progressing stepwise. As the first step, effforts are made to secure the temporary storage of spent fuel. Final disposal is envisaged in an deep repository in one of the main geological media available in Spain, namely, granite, salt and clay. (orig.) [de

  5. Costs of Loyalty Programmes Implementation in Pharmacies

    Directory of Open Access Journals (Sweden)

    Maria Sierpińska

    2010-10-01

    Full Text Available Receiving the customer is in todays market realities top marketing companies. The build a sustainable partnership relation between the seller and the buyer is decide on businesses, takings and profit potential. Increasingly, therefore, perpetuates the view that create lasting relationships is an essential factor in improving the effectiveness of marketing activities conducted by modern businesses. The paper presents the implementation costs of loyalty programmes in pharmacies. These costs are presented based on a study of one of the largest pharmacy loyalty programmes in Poland: I care for health.

  6. A new video programme

    CERN Multimedia

    CERN video productions

    2011-01-01

    "What's new @ CERN?", a new monthly video programme, will be broadcast on the Monday of every month on webcast.cern.ch. Aimed at the general public, the programme will cover the latest CERN news, with guests and explanatory features. Tune in on Monday 3 October at 4 pm (CET) to see the programme in English, and then at 4:20 pm (CET) for the French version.   var flash_video_player=get_video_player_path(); insert_player_for_external('Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0753-kbps-640x360-25-fps-audio-64-kbps-44-kHz-stereo', 'mms://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-Multirate-200-to-753-kbps-640x360-25-fps.wmv', 'false', 480, 360, 'https://mediastream.cern.ch/MediaArchive/Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-posterframe-640x360-at-10-percent.jpg', '1383406', true, 'Video/Public/Movies/2011/CERN-MOVIE-2011-129/CERN-MOVIE-2011-129-0600-kbps-maxH-360-25-fps-...

  7. Environmental monitoring programme

    International Nuclear Information System (INIS)

    1991-08-01

    During 1989 there were about 1000 premises in England and Wales authorised to discharge radioactive wastes. The majority of these premises consisted of hospitals, universities and industrial, research or manufacturing centres. Discharges from these premises when made in accordance with the strict conditions specified in their authorisations will have been of little radiological significance. In the case of nuclear sites authorisations or approvals are issued jointly by the DoE and the Ministry of Agriculture, Fisheries and Food (MAFF) known collectively as the Authorising Departments. In Wales these functions are undertaken by the Welsh Office with the support of HMIP and MAFF. The Authorising Departments specify numerical limits on the amounts of radioactivity which operators may discharge to the environment. In addition operators are required to demonstrate that the best practicable means (BPM) to minimise discharges is undertaken. Operators are also required to carry out appropriate environmental monitoring to demonstrate the effectiveness of BPM. As part of their regulatory functions the Authorising Departments undertake their own environmental monitoring programmes to act as both a check on site operator's returns and to provide independent data on the exposure of the public. HM Inspectorate of Pollution has monitored levels of radioactivity in drinking water sources for many years and published results annually. MAFF undertakes two programmes to monitor radioactivity in the aquatic environment and in terrestrial foodstuffs and publishes annual reports. Environmental monitoring programmes undertaken by both nuclear site operators and government departments are summarised. (author)

  8. 2001 - 2002 ACADEMIC TRAINING PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    1ST TERM 1ST OCTOBER - 23 NOVEMBER 2001 LECTURE SERIES FOR POSTGRADUATE STUDENTS The Autumn term of the Academic Training Programme is about to start. As usual, the first term includes lectures primarily dedicated to Post-graduate students. These are meant to help students complement the courses available from their home Universities with lectures on topics close to CERN activities. The lectures are nevertheless open to all CERN staff, and in particular to young Fellows. This year's series include courses on Accelerator Physics, on Field Theory, and on Symmetry Breaking Phenomena in Physics. The course on Accelerators by Dr. Wilson has been a regular feature on the Academic Training programme for many previous editions. This year, the course will be updated to include new sections on Colliders and on future facilities such as the Neutrino Factory. A good introduction to this very successful course can be found in the previous version of these lectures, available from the Web Lecture Archive Project: http://w...

  9. Quality control programme for radiotherapy

    International Nuclear Information System (INIS)

    Campos de Araujo, A.M.; Viegas, C.C.B.; Viamonte, A.M.

    2002-01-01

    A 3 years pilot programme started in January 2000 with 33 philanthropic cancer institutions that provides medical services to 60% of the patients from the national social security system. Brazil has today 161 radiotherapy services (144 operating with megavoltage equipment). These 33 institutions are distributed over 19 Brazilian states. The aim of this programme is: To create conditions to allow the participants to apply the radiotherapy with quality and efficacy; To promote up dating courses for the physicians, physicists and technicians of these 33 Institutions. With the following objectives: To recommend dosimetric and radiological protection procedures in order to guarantee the tumor prescribed dose and safe working conditions; To help in establishing and implementing these procedures. The main activities are: local quality control evaluations, postal TLD audits in reference conditions, postal TLD audits in off axis conditions and training. The local quality control program has already evaluated 22 institutions with 43 machines (25 Co-60 and 18 linear accelerators). In these visits we perform dosimetric, electrical, mechanical and safety tests. As foreseen, we found more problems among the old Co-60 machines i.e., field flatness, size, symmetry and relative output factors; lasers positioning system alignment; optical distance indicator; radiation and light field coincidence; optical and mechanical distance indicators agreement, than among the linear accelerators i.e., field flatness and size; lasers positioning system alignment; tray interlocking and wedge filter factors

  10. Sellafield Decommissioning Programme - Update and Lessons Learned

    International Nuclear Information System (INIS)

    Lutwyche, P. R.; Challinor, S. F.

    2003-01-01

    The Sellafield site in North West England has over 240 active facilities covering the full nuclear cycle from fuel manufacture through generation, reprocessing and waste treatment. The Sellafield decommissioning programme was formally initiated in the mid 1980s though several plants had been decommissioned prior to this primarily to create space for other plants. Since the initiation of the programme 7 plants have been completely decommissioned, significant progress has been made in a further 16 and a total of 56 major project phases have been completed. This programme update will explain the decommissioning arrangements and strategies and illustrate the progress made on a number of the plants including the Windscale Pile Chimneys, the first reprocessing plan and plutonium plants. These present a range of different challenges and requiring approaches from fully hands on to fully remote. Some of the key lessons learned will be highlighted

  11. The volunteer programme ‘Night Ravens’:

    DEFF Research Database (Denmark)

    Larsen, Britt Østergaard; Kleif, Helle Bendix; Kolodziejczyk, Christophe

    2015-01-01

    The volunteer programme ‘Night Ravens’ (NR) was founded in Sweden in 1987 and has, over the years, developed into a Scandinavian concept covering large areas of Sweden, Denmark, Norway, Greenland and the Faroe Islands. The NR programme is a crime prevention initiative with adults walking...... the streets at night in identifiable ‘uniforms’ in areas with high activity. The purpose of this study is to evaluate the effects of the NR programme in Denmark based on a volunteer set-up with a less intrusive approach to situational crime prevention than, for instance, hot spot policing. The analyses...... are based on a longitudinal data set containing socio-demographic information on all 585 postcode districts in Denmark and quarterly records of six different categories of reported crimes in the years 2001–2010.We apply a difference-in-difference design and compare development in crime rates in districts...

  12. PROPOSAL OF VOIVODESHIP ROAD SAFETY IMPROVEMENT PROGRAMME

    Directory of Open Access Journals (Sweden)

    Tomasz SZCZURASZEK

    2016-07-01

    Full Text Available The article presents a proposal of the ‘GAMBIT KUJAWSKO-POMORSKI’ Road Safety Improvement Programme. The main idea of the Programme is to establish and initiate systems that will be responsible for the most important areas of activity within road safety, including road safety control, supervision, and management systems in the whole Voivodeship. In total, the creation and start of nine such systems has been proposed, namely: the Road Safety Management, the Integrated Road Rescue Service, the Personnel Continuing Education, the Hazardous Road Behaviour Monitoring, the Social Education for Safe Behaviour on Road, the Teaching Personnel Improvement, the Area Development and Planning Process Improvement, the Road Infrastructure Design Quality Improvement, and the Road and Traffic Management Process Efficiency Improvement. The basic aim of each system has been discussed as well as the most important tasks implemented as its part. The Road Safety Improvement Programme for the Kujawsko-Pomorskie Voivodeship presented in this article is a part of the National Road Safety Programme 2013-2020. Moreover, it is not only an original programme in Poland, but also a universal project that may be adapted for other voivodeships as well.

  13. The IAEA's high level radioactive waste management programme

    International Nuclear Information System (INIS)

    Saire, D.E.

    1994-01-01

    This paper presents the different activities that are performed under the International Atomic Energy Agency's (IAEA) high level radioactive waste management programme. The Agency's programme is composed of five main activities (information exchange, international safety standards, R ampersand D activities, advisory services and special projects) which are described in the paper. Special emphasis is placed on the RADioactive WAste Safety Standards (RADWASS) programme which was implemented in 1991 to document international consensus that exists on the safe management of radioactive waste. The paper also raises the question about the need for regional repositories to serve certain countries that do not have the resources or infrastructure to construct a national repository

  14. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study

    Directory of Open Access Journals (Sweden)

    Withall Janet

    2012-10-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government’s recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. Methods A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Results Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005, Month 5 (3.45v.84 p=.007, 3.45v.30 p Conclusions Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area, monthly attendance patterns indicated that a reasonably well funded social marketing campaign increased recruitment into exercise sessions, maintained good levels of attendance and reasonable levels

  15. The effect a of community-based social marketing campaign on recruitment and retention of low-income groups into physical activity programmes - a controlled before-and-after study.

    Science.gov (United States)

    Withall, Janet; Jago, Russell; Fox, Kenneth R

    2012-10-02

    The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These conditions are most prevalent in low-income groups where physical activity levels are consistently lower. Social marketing is the government's recommended approach to promoting physical activity but evidence of its effectiveness is limited. The purpose of this study was to examine the effect of a social marketing campaign on the monthly recruitment, attendance and retention levels at a community-based physical activity programme in a low income area. A six-month social marketing campaign was designed and delivered in a highly-deprived suburban neighbourhood. Analysis of variance was used to assess effects on recruitment and attendance. χ2 tests of independence were used to compare dropouts and adherers and effectiveness of recruitment mechanisms. Percentages were used to compare adherence rates at intervention, pre-existing sessions in the intervention area and control area sessions. Attendance data were collected weekly and presented and analysed monthly to provide a view of changing participation over the six month intervention period, as compared to attendance at pre-existing sessions in the intervention area and in a control area. Recruitment into intervention sessions was significantly greater than into pre-existing and control area sessions in Month 1 (18.13v1.04 p = .007, 18.13v.30 p=.005), Month 5 (3.45v.84 p=.007, 3.45v.30 pmarketing techniques (posters/outdoor banners/flyers) had the greatest influence on recruitment compared to word of mouth communication (84.5%v15.5%). In months five and six word of mouth influenced 57.5% of new recruits. Direct comparisons with other programmes were difficult due to a lack of standard definitions of recruitment and adherence and limited reporting of findings. However when compared to pre-existing sessions and sessions delivered in a control area, monthly attendance patterns indicated that a

  16. Intergenerational Influence of Paternal Obesity on Metabolic and Reproductive Health Parameters of the Offspring: Male-Preferential Impact and Involvement of Kiss1-Mediated Pathways.

    Science.gov (United States)

    Sanchez-Garrido, Miguel Angel; Ruiz-Pino, Francisco; Velasco, Inmaculada; Barroso, Alexia; Fernandois, Daniela; Heras, Violeta; Manfredi-Lozano, Maria; Vazquez, Maria Jesus; Castellano, Juan Manuel; Roa, Juan; Pinilla, Leonor; Tena-Sempere, Manuel

    2018-02-01

    Obesity and its comorbidities are reaching epidemic proportions worldwide. Maternal obesity is known to predispose the offspring to metabolic disorders, independently of genetic inheritance. This intergenerational transmission has also been suggested for paternal obesity, with a potential negative impact on the metabolic and, eventually, reproductive health of the offspring, likely via epigenetic changes in spermatozoa. However, the neuroendocrine component of such phenomenon and whether paternal obesity sensitizes the offspring to the disturbances induced by high-fat diet (HFD) remain poorly defined. We report in this work the metabolic and reproductive impact of HFD in the offspring from obese fathers, with attention to potential sex differences and alterations of hypothalamic Kiss1 system. Lean and obese male rats were mated with lean virgin female rats; male and female offspring were fed HFD from weaning onward and analyzed at adulthood. The increases in body weight and leptin levels, but not glucose intolerance, induced by HFD were significantly augmented in the male, but not female, offspring from obese fathers. Paternal obesity caused a decrease in luteinizing hormone (LH) levels and exacerbated the drop in circulating testosterone and gene expression of its key biosynthetic enzymes caused by HFD in the male offspring. LH responses to central kisspeptin-10 administration were also suppressed in HFD males from obese fathers. In contrast, paternal obesity did not significantly alter gonadotropin levels in the female offspring fed HFD, although these females displayed reduced LH responses to kisspeptin-10. Our findings suggest that HFD-induced metabolic and reproductive disturbances are exacerbated by paternal obesity preferentially in males, whereas kisspeptin effects are affected in both sexes. Copyright © 2018 Endocrine Society.

  17. Contribution of the Member State Support Programmes to IAEA safeguards

    International Nuclear Information System (INIS)

    Fortakov, V.; Gardiner, D.; Rautjaervi, J.

    1999-01-01

    Over the last twenty years, Member States of the International Atomic Energy Agency (IAEA) have provided invaluable technical support to IAEA Safeguards. This support has covered practically all aspects of traditional safeguards activities and also those activities recently proposed and introduced for strengthening the safeguards system. As of August 1997, there were fourteen Member States, plus EURATOM, with active programmes in support of IAEA safeguards and the activities conducted under these Member State Support Programmes (MSSPs) are currently valued at an annual twenty million dollars of extra-budgetary contribution to the IAEA. The overall administration in the IAEA of the support programmes is the responsibility of Support Programmes Administration (SPA) in the Safeguards Division of Technical Services. This paper describes the roles and the contributions of the MSSPs, the functions of the MSSP administration activities, and the vital importance the IAEA attaches to the MSSPs. (author)

  18. Changes in activity of industrial enzyme preparations irradiated with sterilizing doses. Part of a coordinated programme on factors influencing the utilization of food irradiation process

    International Nuclear Information System (INIS)

    Bachman, S.

    1984-03-01

    Experiments were carried out to investigate the efficacy of irradiation to sterilize enzyme preparations. Irradiation doses up to 25 kGy caused no changes in basic organoleptic properties of commercial rennin preparations. Dose rate (from 0.5 to 13.5 kGy/hr) has no influence on the changes in enzyme activity during the storage period of 3 months. Doses ranging from 8 to 12 kGy are sufficient to sterilize commercial enzyme preparations. Non-purified, crude rennin preparations appear to be more resistant to radiation than purified samples. Rennin preparations purified by dialysis and treated with 25 kGy resulted in a reduction of activity of 20%. The activity of preparations purified by gel filtration was reduced to 50% when treated with the same dose

  19. FFUSION research programme 1993-1998. Final report of the Finnish fusion research programme

    Energy Technology Data Exchange (ETDEWEB)

    Karttunen, S.; Heikkinen, J.; Korhonen, R. [VTT Energy, Espoo (Finland)] [and others

    1998-12-31

    This report summarizes the results of the Fusion Energy Research Programme, FFUSION, during the period 1993-1998. After the planning phase the programme started in 1994, and later in March 1995 the FFUSION Programme was integrated into the EU Fusion Programme and the Association Euratom-Tekes was established. Research areas in the FFUSION Programme are (1) fusion physics and plasma engineering, (2) fusion reactor materials and (3) remote handling systems. In all research areas industry is involved. Recently, a project on environmental aspects of fusion and other future energy systems started as a part of the socio-economic research (SERF) in the Euratom Fusion Programme. A crucial component of the FFUSION programme is the close collaboration between VTT Research Institutes, universities and Finnish industry. This collaboration has guaranteed dynamic and versatile research teams, which are large enough to tackle challenging research and development projects. Regarding industrial fusion R and D activities, the major step was the membership of Imatran Voima Oy in the EFET Consortium (European Fusion Engineering and Technology), which further strengthened the position of industry in the engineering design activities of ITER. The number of FFUSION research projects was 66. In addition, there were 32 industrial R and D projects. The total cost of the FFUSION Programme in 1993-1998 amounted to FIM 54 million in research at VTT and universities and an additional FIM 21 million for R and D in Finnish industry. The main part of the funding was provided by Tekes, 36%. Since 1995, yearly Euratom funding has exceeded 25%. The FFUSION research teams have played an active role in the European Programme, receiving excellent recognition from the European partners. Theoretical and computational fusion physics has been at a high scientific level and the group collaborates with the leading experimental laboratories in Europe. Fusion technology is focused on reactor materials, joining

  20. FFUSION research programme 1993-1998. Final report of the Finnish fusion research programme

    International Nuclear Information System (INIS)

    Karttunen, S.; Heikkinen, J.; Korhonen, R.