The Development of Environmental Guide Training Activities For Conservation Tourism in Ubonrat District, Khonkean

Directory of Open Access Journals (Sweden)

Kosin Sata

2016-10-01

Full Text Available The purposes of this research on the development of training activities environmental guide to environmental conservation tourism Ubonrat district, Khonkean province were to 1 To study the problem of tourist place in ubonrat district Khonkean province, 2 to develop training activities environmental guide to environmental conservation tourism Ubonrat district, Khonkean province 3 to study and compare the knowledge, attitude and skills as a guide about ecotourism in Ubonrat district before and after the training. The sample were of 50 youth in Ubonrat district, who voluntarily participated in training. The research tools were the manual training activities environmental guide to environmental conservation tourism Ubonrat district, Khonkaen province, knowledge test, attitude test and skills test as a environmental guide. The statistical analysis of data were percentage, mean, standard deviation, and Paired t-test. results showed that the tourist attraction in Ubonrat district, Khonkean province had importance 3 source ; Nam Phong national park, Ubolrat Dam, Phu koa–Phu Phan kham national park. The findings revealed that environmental guide training activities development for ecotourism had approviatences. Comparing the score of knowledge, attitude and skill as a environmental guide of youths after the training higher than those before the training at .05 level of significance.

Activity-guided identification of acetogenins as novel lipophilic antioxidants present in avocado pulp (Persea americana).

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Rodríguez-Sánchez, Dariana; Silva-Platas, Christian; Rojo, Rocío P; García, Noemí; Cisneros-Zevallos, Luis; García-Rivas, Gerardo; Hernández-Brenes, Carmen

2013-12-30

Avocado fruit is a rich source of health-related lipophilic phytochemicals such as monounsaturated fatty acids, tocopherols, carotenes, acetogenins and sterols. However, limited information is available on the contribution of specific phytochemicals to the overall antioxidant capacity (AOC) of the fruit. Centrifugal partition chromatography was used as fractionation tool, guided by an in vitro chemical assay of oxygen radical absorbance capacity (ORAC). Subsequent experiments focused on isolation and characterization of the chemical nature of the main contributors to lipophilic AOC of avocado pulp. ORAC values obtained for acetogenins were contrasted with results from an isolated kidney mitochondria membrane lipid peroxidation bioassay. The present study established that lipophilic AOC of the pulp was significantly higher than its hydrophilic AOC. Our results confirmed the presence of acetogenins in the fractions with highest lipophilic AOC, and for the first time linked them as contributors to lipophilic-ORAC values. Further HPLC-PDA/MS-TOF analysis led to structural elucidation of two novel acetogenins, not previously reported as present in avocado pulp, along with five already known related-compounds. Antioxidant properties observed for avocado pulp acetogenins by the ORAC assay suggested that, in the presence of an emulsifying agent, acetogenins could serve as novel lipophilic antioxidants in a food matrix. Results from isolated mitochondria lipid peroxidation bioassay, indicated that L-ORAC values which may have relevance for food matrix applications, should not be interpreted to have a direct relevance in health-related claims, compounds need to be evaluated considering the complexity of biological systems. Copyright © 2013 Elsevier B.V. All rights reserved.

Do You Read Me? Service Supplement: Reading Development Activities Guide.

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Kendall, Elizabeth L.; Chenoweth, Roberta

This activity guide is one of four supplements to be used with "Do You Read Me? Prevocational-Vocational Reading Development Activities" (ED 210 454). Each supplement deals with a different occupational category. Games, puzzles, and other activities are offered to aid in developing the word recognition, vocabulary, and comprehension…

Modulation of Neural Activity during Guided Viewing of Visual Art.

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Herrera-Arcos, Guillermo; Tamez-Duque, Jesús; Acosta-De-Anda, Elsa Y; Kwan-Loo, Kevin; de-Alba, Mayra; Tamez-Duque, Ulises; Contreras-Vidal, Jose L; Soto, Rogelio

2017-01-01

Mobile Brain-Body Imaging (MoBI) technology was deployed to record multi-modal data from 209 participants to examine the brain's response to artistic stimuli at the Museo de Arte Contemporáneo (MARCO) in Monterrey, México. EEG signals were recorded as the subjects walked through the exhibit in guided groups of 6-8 people. Moreover, guided groups were either provided with an explanation of each art piece (Guided-E), or given no explanation (Guided-NE). The study was performed using portable Muse (InteraXon, Inc, Toronto, ON, Canada) headbands with four dry electrodes located at AF7, AF8, TP9, and TP10. Each participant performed a baseline (BL) control condition devoid of artistic stimuli and selected his/her favorite piece of art (FP) during the guided tour. In this study, we report data related to participants' demographic information and aesthetic preference as well as effects of art viewing on neural activity (EEG) in a select subgroup of 18-30 year-old subjects (Nc = 25) that generated high-quality EEG signals, on both BL and FP conditions. Dependencies on gender, sensor placement, and presence or absence of art explanation were also analyzed. After denoising, clustering of spectral EEG models was used to identify neural patterns associated with BL and FP conditions. Results indicate statistically significant suppression of beta band frequencies (15-25 Hz) in the prefrontal electrodes (AF7 and AF8) during appreciation of subjects' favorite painting, compared to the BL condition, which was significantly different from EEG responses to non-favorite paintings (NFP). No significant differences in brain activity in relation to the presence or absence of explanation during exhibit tours were found. Moreover, a frontal to posterior asymmetry in neural activity was observed, for both BL and FP conditions. These findings provide new information about frequency-related effects of preferred art viewing in brain activity, and support the view that art appreciation is

MiDAS: the field guide to the microbes of activated sludge.

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McIlroy, Simon Jon; Saunders, Aaron Marc; Albertsen, Mads; Nierychlo, Marta; McIlroy, Bianca; Hansen, Aviaja Anna; Karst, Søren Michael; Nielsen, Jeppe Lund; Nielsen, Per Halkjær

2015-01-01

The Microbial Database for Activated Sludge (MiDAS) field guide is a freely available online resource linking the identity of abundant and process critical microorganisms in activated sludge wastewater treatment systems to available data related to their functional importance. Phenotypic properties of some of these genera are described, but most are known only from sequence data. The MiDAS taxonomy is a manual curation of the SILVA taxonomy that proposes a name for all genus-level taxa observed to be abundant by large-scale 16 S rRNA gene amplicon sequencing of full-scale activated sludge communities. The taxonomy can be used to classify unknown sequences, and the online MiDAS field guide links the identity to the available information about their morphology, diversity, physiology and distribution. The use of a common taxonomy across the field will provide a solid foundation for the study of microbial ecology of the activated sludge process and related treatment processes. The online MiDAS field guide is a collaborative workspace intended to facilitate a better understanding of the ecology of activated sludge and related treatment processes--knowledge that will be an invaluable resource for the optimal design and operation of these systems. © The Author(s) 2015. Published by Oxford University Press.

California Women: Activities Guide, Kindergarten through Grade Twelve.

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McLean, Marie

Women have always been an integral part of California's history as shamans, settlers, wives, mothers, workers, inventors, and reformers. Yet the names of California women may not be familiar to many students. This activities guide, which was designed to accompany the poster, "California Women: Courage, Compassion, Conviction," provides…

MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

DEFF Research Database (Denmark)

Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

activated sludge wastewater treatment systems, linking their identity with available information on their function and distribution. The guide includes the approx. 100 abundant genera that are present in most treatment plants (based on a survey of 25 full-scale Danish wastewater treatment plants...... are provided. The MiDAS Field Guide is a continuously developing resource where all working in the field are invited to contribute....... that would be otherwise excluded from analyses. The MiDAS database importantly provides a common taxonomy for the field that gives a solid foundation for the study of microbial ecology of the activated sludge process and related wastewater treatment processes, such as biofilms and granular sludge. Each genus...

Space-Based Astronomy: An Educator Guide with Activities for Science, Mathematics, and Technology Education

Science.gov (United States)

Vogt, Gregory L.

2001-01-01

If you go to the country, far from city lights, you can see about 3,000 stars on a clear night. If your eyes were bigger, you could see many more stars. With a pair of binoculars, an optical device that effectively enlarges the pupil of your eye by about 30 times, the number of stars you can see increases to the tens of thousands. With a medium-sized telescope with a light-collecting mirror 30 centimeters in diameter, you can see hundreds of thousands of stars. With a large observatory telescope, millions of stars become visible. This curriculum guide uses hands-on activities to help students and teachers understand the significance of space-based astronomy--astronomical observations made from outer space. It is not intended to serve as a curriculum. Instead, teachers should select activities from this guide that support and extend existing study. The guide contains few of the traditional activities found in many astronomy guides such as constellation studies, lunar phases, and planetary orbits. It tells, rather, the story of why it is important to observe celestial objects from outer space and how to study the entire electromagnetic spectrum. Teachers are encouraged to adapt these activities for the particular needs of their students. When selected activities from this guide are used in conjunction with traditional astronomy curricula, students benefit from a more complete experience.

Active Metamaterial Based Ultrasonic Guided Wave Transducer System, Phase I

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National Aeronautics and Space Administration — An active and tunable metamaterial phased array transducer for guided wave mode selection with high intensity per driving channel and with dramatically lower modal...

Disparity in Physical Activity among Urban Youth: An Ecologically Guided Assessment

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Lenhart, Clare M.; Patterson, Freda; Brown, Michael D.; O'Brien, Matthew J.; Nelson, Deborah B.

2014-01-01

Background: Insufficient physical activity among urban youth increases risk of chronic disease.Purpose:This study assessed reported physical activity to determine when disparities in participation emerge and what ecologically guided factors are linked with high activity. Methods:We administered a cross-sectional survey to a diverse sample of 321…

Strychnos pseudoquina and Its Purified Compounds Present an Effective In Vitro Antileishmanial Activity

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Paula Sousa Lage

2013-01-01

Full Text Available The development of new and cost-effective alternative therapeutic strategies to treat leishmaniasis has become a high priority. In the present study, the antileishmanial activity of Strychnos pseudoquina St. Hil. was investigated and pure compounds that presented this biological effect were isolated. An ethyl acetate extract was prepared, and it proved to be effective against Leishmania amazonensis. A bioactivity-guided fractionation was performed, and two flavonoids were identified, quercetin 3-O-methyl ether and strychnobiflavone, which presented an effective antileishmanial activity against L. amazonensis, and studies were extended to establish their minimum inhibitory concentrations (IC50, their leishmanicidal effects on the intra-macrophage Leishmania stage, as well as their cytotoxic effects on murine macrophages (CC50, and in O+ human red blood cells. The data presented in this study showed the potential of an ethyl acetate extract of S. pseudoquina, as well as two flavonoids purified from it, which can be used as a therapeutic alternative on its own, or in association with other drugs, to treat disease evoked by L. amazonensis.

Rockets: Educator's Guide with Activities in Science, Technology, Engineering and Mathematics

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Shearer, Deborah A.; Vogt, Gregory L.

2008-01-01

This guide provides teachers and students many opportunities. Chapters within the guide present the history of rocketry, National Aeronautics and Space Administration's (NASA's) 21st Century Space Exploration Policy, rocketry principles, and practical rocketry. These topics lay the foundation for what follows--a wealth of dynamic rocket science…

International nuclear energy guide

International Nuclear Information System (INIS)

Anon.

1983-01-01

Separate abstracts are included for each of the papers presented concerning current technical and economical events in the nuclear field. Twelve papers have been abstracted and input to the data base. The ''international nuclear energy guide'' gives a general directory of the name, the address and the telephone number of the companies and bodies quoted in this guide; a chronology of the main events 1982. The administrative and professional organization, the nuclear courses and research centers in France are presented, as also the organization of protection and safety, and of nuclear fuel cycle. The firms concerned by the design and the construction of NSSS and the allied nuclear firms are also presented. The last part of this guide deals with the nuclear energy in the world: descriptive list of international organizations, and, the nuclear activities throughout the world (alphabetical order by countries) [fr

Multiple Active Contours Guided by Differential Evolution for Medical Image Segmentation

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Cruz-Aceves, I.; Avina-Cervantes, J. G.; Lopez-Hernandez, J. M.; Rostro-Gonzalez, H.; Garcia-Capulin, C. H.; Torres-Cisneros, M.; Guzman-Cabrera, R.

2013-01-01

This paper presents a new image segmentation method based on multiple active contours guided by differential evolution, called MACDE. The segmentation method uses differential evolution over a polar coordinate system to increase the exploration and exploitation capabilities regarding the classical active contour model. To evaluate the performance of the proposed method, a set of synthetic images with complex objects, Gaussian noise, and deep concavities is introduced. Subsequently, MACDE is applied on datasets of sequential computed tomography and magnetic resonance images which contain the human heart and the human left ventricle, respectively. Finally, to obtain a quantitative and qualitative evaluation of the medical image segmentations compared to regions outlined by experts, a set of distance and similarity metrics has been adopted. According to the experimental results, MACDE outperforms the classical active contour model and the interactive Tseng method in terms of efficiency and robustness for obtaining the optimal control points and attains a high accuracy segmentation. PMID:23983809

Multiple Active Contours Guided by Differential Evolution for Medical Image Segmentation

Directory of Open Access Journals (Sweden)

I. Cruz-Aceves

2013-01-01

Full Text Available This paper presents a new image segmentation method based on multiple active contours guided by differential evolution, called MACDE. The segmentation method uses differential evolution over a polar coordinate system to increase the exploration and exploitation capabilities regarding the classical active contour model. To evaluate the performance of the proposed method, a set of synthetic images with complex objects, Gaussian noise, and deep concavities is introduced. Subsequently, MACDE is applied on datasets of sequential computed tomography and magnetic resonance images which contain the human heart and the human left ventricle, respectively. Finally, to obtain a quantitative and qualitative evaluation of the medical image segmentations compared to regions outlined by experts, a set of distance and similarity metrics has been adopted. According to the experimental results, MACDE outperforms the classical active contour model and the interactive Tseng method in terms of efficiency and robustness for obtaining the optimal control points and attains a high accuracy segmentation.

The CAREM project: Present status and development activities

International Nuclear Information System (INIS)

Boado Magan, H.J.; Ordonez, J.P.; Hey, A.

1997-01-01

The CAREM Project is a low power NPP of 25 Mwe, with an integrated self pressurized primary system. The cooling of the primary system is of the natural circulation type and several passive safety systems are included. The owner of the Project is Argentina's CNEA (Comision Nacional de Energia Atomica) and its associated company, INVAP, is the main contractor. The present status of the CAREM Project is presented. The possible evolution of the CAREM project is mentioned in relation with a new containment design. A short description of the Experimental Facilities, listed below, already in operation and under construction are also included: CAPCN High Pressure Loop. Natural convection loop to verify dynamic response and critical heat flux; RA-8. Critical Facility, designed and constructed for the CAREM Project (that may be used as a general uses facility); RPV lnternals. The whole assembly of absorbent rods, connecting rods and the rode guides are being constructed in a 1:1 scale. The aims of this experimental facility are vibration analysis and manufacturing parameters definitions. Control Drive Mechanisms. A series of verification and tests are being carried out on these within RPV Hydraulically driven mechanisms. Other development activities are mentioned in relation with the thermalhydraulics, Steam Generators and Control. (author)

Ute Unit: Study Guide and Follow Up Activities.

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North Conejos School District, Capulin, CO.

The study guide and follow-up activities were designed primarily to give students a feeling of Ute life in the San Luis Valley in Colorado. The unit begins with six Southern Ute stories about the wolf and coyote, the race between the skunk and the coyote, the frog and the eagle, why the frog croaks, the bear (Que Ye Qat), and the two Indian…

The Effectiveness of WhatsApp Mobile Learning Activities Guided by Activity Theory on Students' Knowledge Management

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Barhoumi, Chokri

2015-01-01

This research paper explores the effectiveness of using mobile technologies to support a blended learning course titled Scientific Research Methods in Information Science. Specifically, it discusses the effects of WhatsApp mobile learning activities guided by activity theory on students' knowledge Management (KM). During the 2014 academic year,…

South Carolina Guide for Sales Promotion. Marketing Education.

Science.gov (United States)

Elliott, Ronald T.

This guide presents a competency-based curriculum for a high school course in sales promotion. It addresses all three domains of learning: psychomotor, cognitive, and affective. Activities suggested in the guide deal with getting along with others, with supervisors or staff members, and with small or large groups. The guide, which can be used with…

WE-EF-BRD-01: Past, Present and Future: MRI-Guided Radiotherapy From 2005 to 2025

Energy Technology Data Exchange (ETDEWEB)

Lagendijk, J. [University Medical Center Utrecht (Netherlands)

2015-06-15

MRI-guided treatment is a growing area of medicine, particularly in radiotherapy and surgery. The exquisite soft tissue anatomic contrast offered by MRI, along with functional imaging, makes the use of MRI during therapeutic procedures very attractive. Challenging the utility of MRI in the therapy room are many issues including the physics of MRI and the impact on the environment and therapeutic instruments, the impact of the room and instruments on the MRI; safety, space, design and cost. In this session, the applications and challenges of MRI-guided treatment will be described. The session format is: Past, present and future: MRI-guided radiotherapy from 2005 to 2025: Jan Lagendijk Battling Maxwell’s equations: Physics challenges and solutions for hybrid MRI systems: Paul Keall I want it now!: Advances in MRI acquisition, reconstruction and the use of priors to enable fast anatomic and physiologic imaging to inform guidance and adaptation decisions: Yanle Hu MR in the OR: The growth and applications of MRI for interventional radiology and surgery: Rebecca Fahrig Learning Objectives: To understand the history and trajectory of MRI-guided radiotherapy To understand the challenges of integrating MR imaging systems with linear accelerators To understand the latest in fast MRI methods to enable the visualisation of anatomy and physiology on radiotherapy treatment timescales To understand the growing role and challenges of MRI for image-guided surgical procedures My disclosures are publicly available and updated at: http://sydney.edu.au/medicine/radiation-physics/about-us/disclosures.php.

DOING OTHER PEOPLE’S TRAINING PRESENTATIONS - a guide for teachers in implementing a scheme

OpenAIRE

Neal, Ian

2008-01-01

Often, experienced teachers in schools and colleges are asked to present training packs written by others. The assumption is that since they are experienced teachers, making training presentations to their colleagues will be easy. They often find that it is not. Usually, the material has been designed to be delivered using a model where one person within a school or college will make themselves responsible for familiarising themselves with Trainer's Notes, the Teachers' Guide and the rest of ...

Predicting activities of daily living for cancer patients using an ontology-guided machine learning methodology.

Science.gov (United States)

Min, Hua; Mobahi, Hedyeh; Irvin, Katherine; Avramovic, Sanja; Wojtusiak, Janusz

2017-09-16

Bio-ontologies are becoming increasingly important in knowledge representation and in the machine learning (ML) fields. This paper presents a ML approach that incorporates bio-ontologies and its application to the SEER-MHOS dataset to discover patterns of patient characteristics that impact the ability to perform activities of daily living (ADLs). Bio-ontologies are used to provide computable knowledge for ML methods to "understand" biomedical data. This retrospective study included 723 cancer patients from the SEER-MHOS dataset. Two ML methods were applied to create predictive models for ADL disabilities for the first year after a patient's cancer diagnosis. The first method is a standard rule learning algorithm; the second is that same algorithm additionally equipped with methods for reasoning with ontologies. The models showed that a patient's race, ethnicity, smoking preference, treatment plan and tumor characteristics including histology, staging, cancer site, and morphology were predictors for ADL performance levels one year after cancer diagnosis. The ontology-guided ML method was more accurate at predicting ADL performance levels (P ontologies. This study demonstrated that bio-ontologies can be harnessed to provide medical knowledge for ML algorithms. The presented method demonstrates that encoding specific types of hierarchical relationships to guide rule learning is possible, and can be extended to other types of semantic relationships present in biomedical ontologies. The ontology-guided ML method achieved better performance than the method without ontologies. The presented method can also be used to promote the effectiveness and efficiency of ML in healthcare, in which use of background knowledge and consistency with existing clinical expertise is critical.

Suited for spacewalking: Teacher's guide with activities for physical and life science

Science.gov (United States)

Vogt, Gregory L.; Manning, Cheryl A.; Rosenberg, Carla B.

1994-01-01

Space walking has captured the imagination of generations of children and adults since science-fiction authors first placed their characters on the Moon. This publication is an activity guide for teachers interested in using the intense interest many children have in space exploration as a launching point for exciting hands-on learning opportunities. The guide begins with brief discussions of the space environment, the history of space walking, the Space Shuttle spacesuit, and working in space. These are followed by a series of activities that enable children to explore the space environment as well as the science and technology behind the functions of spacesuits. The activities are not rated for specific grade levels because they can be adapted for students of many ages. The chart on curriculum application at the back of the book is designed to help teachers incorporate activities into various subject areas.

Business and Office Education: Accounting, Clerk. Instructor's Manual [and] Student Learning Activity Guide. Kit No. 204.

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Cliatt, Katherine H.

This learning activity guide and instructor's manual provide information and exercises for an exploratory activity in accounting. Instructional objectives covered in the guide are for the students to learn (1) reasons for studying accounting and related job descriptions, (2) definitions for accounting terms, (3) the accounting equation, (4) how to…

Guided goal setting: effectiveness in a dietary and physical activity intervention with low-income adolescents.

Science.gov (United States)

Shilts, Mical Kay; Horowitz, Marcel; Townsend, Marilyn S

2009-01-01

Determining the effectiveness of the guided goal setting strategy on changing adolescents' dietary and physical activity self-efficacy and behaviors. Adolescents were individually assigned to treatment (intervention with guided goal setting) or control conditions (intervention without guided goal setting) with data collected before and after the education intervention. Urban middle school in a low-income community in Central California. Ethnically diverse middle school students (n = 94, 55% male) who were participants of a USDA nutrition education program. Driven by the Social Cognitive Theory, the intervention targeted dietary and physical activity behaviors of adolescents. Dietary self-efficacy and behavior; physical activity self-efficacy and behavior; goal effort and spontaneous goal setting. ANCOVA and path analysis were performed using the full sample and a sub-sample informed by Locke's recommendations (accounting for goal effort and spontaneous goal setting). No significant differences were found between groups using the full sample. Using the sub-sample, greater gains in dietary behavior (p goal effort and spontaneous goal setting, this study provides some evidence that the use of guided goal setting with adolescents may be a viable strategy to promote dietary and physical activity behavior change.

Guided participation in cultural activity by toddlers and caregivers.

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Rogoff, B; Mistry, J; Göncü, A; Mosier, C

1993-01-01

In this Monograph, we examine how toddlers and their caregivers from four cultural communities collaborate in shared activities. We focus both on similarities across communities in processes of guided participation--structuring children's participation and bridging between their understanding and that of their caregivers--and on differences in how guided participation occurs. We examine the idea that a key cultural difference entails who is responsible for learning--whether adults take this responsibility by structuring teaching situations or whether children take responsibility for learning through observation and through participating in adult activities with caregivers' support. We speculate that these two patterns relate to cultural variation in the segregation of children from adult activities of their community and in emphasis on formal schooling. The four communities of our study vary along these lines as well as in other ways: a Mayan Indian town in Guatemala, a middle-class urban group in the United States, a tribal village in India, and a middle-class urban neighborhood in Turkey. In each community, we visited the families of 14 toddlers (aged 12-24 months) for an interview that was focused on child-rearing practices, which included observations of caregivers helping the toddlers operate novel objects spontaneously during adult activities. Results are based on systematic analysis of patterns of communication and attention in each family in each community, combining the tools of ethnographic description, graphic analysis, and statistics.(ABSTRACT TRUNCATED AT 250 WORDS)

MiDAS Field Guide – a Comprehensive Online Source of Information About the Microbes of Activated Sludge

DEFF Research Database (Denmark)

Nierychlo, Marta; McIlroy, Simon Jon; Saunders, Aaron Marc

this information in MiDAS field guide (www.midasfieldguide.org). MiDAS taxonomy gives a solid foundation for the study of microbial ecology of the wastewater treatment processes. The online MiDAS field guide links the identity of genera that are important for the wastewater treatment process to details about...... guide to the microbes of activated sludge by comparing microbial community composition in 32 WWTPs located worldwide. This will facilitate a better understanding of the ecology of the ecosystem of activated sludge. Reference: McIlroy et al. MiDAS: the field guide to the microbes of activated sludge...... on a survey of 25 full-scale Danish wastewater treatment plants over 6 years and using MiDAS taxonomy, we have collected more than 150 key organisms in activated sludge wastewater treatment systems, linked their identity with available information on their function and distribution and included...

Recycle Alaska: Reduce, Reuse, Recycle. Activities Handbook, Teacher's Guide, and Student Worksheets.

Science.gov (United States)

Alaska State Dept. of Education, Juneau.

Recycling is a very important aspect of conserving the environment for future generations. This guide addresses the topic of litter prevention for the Alaskan environment and contains 42 activities. Activity topics covered include Natural Cycles, Human Interruption of Natural Cycles, Reduce, Reuse, Recycle and Recycled Classroom. Grade level,…

PET/CT-guided biopsies of metabolically active bone lesions: applications and clinical impact

Energy Technology Data Exchange (ETDEWEB)

Klaeser, Bernd; Wartenberg, Jan; Weitzel, Thilo; Krause, Thomas [Bern University Hospital and University of Bern, Department of Nuclear Medicine, Inselspital, Bern (Switzerland); Wiskirchen, Jakub [Bern University Hospital and University of Bern, Department of Nuclear Medicine, Inselspital, Bern (Switzerland); University Hospital Tuebingen, Department of Radiology, Neuroradiology, and Nuclear Medicine, Tuebingen (Germany); Schmid, Ralph A. [Bern University Hospital and University of Bern, Department of Thoracic Surgery, Inselspital, Bern (Switzerland); Mueller, Michel D. [Bern University Hospital and University of Bern, Department of Obstetrics and Gynaecology, Inselspital, Bern (Switzerland)

2010-11-15

In a minority of cases a definite diagnosis and stage grouping in cancer patients is not possible based on the imaging information of PET/CT. We report our experience with percutaneous PET/CT-guided bone biopsies to histologically verify the aetiology of hypermetabolic bone lesions. We retrospectively reviewed the data of 20 consecutive patients who underwent multimodal image-guided bone biopsies using a dedicated PET/CT system in a step-by-step technique. Technical and clinical success rates of PET/CT-guided biopsies were evaluated. Questionnaires were sent to the referring physicians to assess the impact of biopsies on patient management and to check the clinical need for PET/CT-guided biopsies. Clinical indications for biopsy were to histologically verify the aetiology of metabolically active bone lesions without a morphological correlate confirming the suspicion of metastases in 15 patients, to determine the origin of suspected metastases in 3 patients and to evaluate the appropriateness of targeted therapy options in 2 patients. Biopsies were technically successful in all patients. In 19 of 20 patients a definite histological diagnosis was possible. No complications or adverse effects occurred. The result of PET/CT-guided bone biopsies determined a change of the planned treatment in overall 56% of patients, with intramodality changes, e.g. chemotherapy with palliative instead of curative intent, and intermodality changes, e.g. systemic therapy instead of surgery, in 22 and 50%, respectively. PET/CT-guided bone biopsies are a promising alternative to conventional techniques to make metabolically active bone lesions - especially without a distinctive morphological correlate - accessible for histological verification. PET/CT-guided biopsies had a major clinical impact in patients who otherwise cannot be reliably stage grouped at the time of treatment decisions. (orig.)

Choosing the Future You Prefer. A Goal Setting Guide.

Science.gov (United States)

Lindaman, Edward B.; Lippitt, Ronald O.

The guide, intended for group and organization leaders, presents activities and exercises to aid in personal and group goal-setting and planning for the future. The objective is to help groups choose goals which are sensitive to and oriented toward the evolving future with its rapid rate of change. The guide is presented in eight chapters.…

Task Rotation: Strategies for Differentiating Activities and Assessments by Learning Style. A Strategic Teacher PLC Guide

Science.gov (United States)

Silver, Harvey; Moirao, Daniel; Jackson, Joyce

2011-01-01

One of the hardest jobs in teaching is to differentiate learning activities and assessments to your students' learning styles. But you and your colleagues can learn how to do this together when each of you has this guide to the Task Rotation strategy from our ultimate guide to teaching strategies, "The Strategic Teacher". Use the guide in your…

Guiding transcranial brain stimulation by EEG/MEG to interact with ongoing brain activity and associated functions

DEFF Research Database (Denmark)

Thut, Gregor; Bergmann, Til Ole; Fröhlich, Flavio

2017-01-01

of NTBS with respect to the ongoing brain activity. Temporal patterns of ongoing neuronal activity, in particular brain oscillations and their fluctuations, can be traced with electro- or magnetoencephalography (EEG/MEG), to guide the timing as well as the stimulation settings of NTBS. These novel, online...... and offline EEG/MEG-guided NTBS-approaches are tailored to specifically interact with the underlying brain activity. Online EEG/MEG has been used to guide the timing of NTBS (i.e., when to stimulate): by taking into account instantaneous phase or power of oscillatory brain activity, NTBS can be aligned......Non-invasive transcranial brain stimulation (NTBS) techniques have a wide range of applications but also suffer from a number of limitations mainly related to poor specificity of intervention and variable effect size. These limitations motivated recent efforts to focus on the temporal dimension...

Guide to the assessment of physical activity: Clinical and research applications: a scientific statement from the American Heart Association.

Science.gov (United States)

Strath, Scott J; Kaminsky, Leonard A; Ainsworth, Barbara E; Ekelund, Ulf; Freedson, Patty S; Gary, Rebecca A; Richardson, Caroline R; Smith, Derek T; Swartz, Ann M

2013-11-12

The deleterious health consequences of physical inactivity are vast, and they are of paramount clinical and research importance. Risk identification, benchmarks, efficacy, and evaluation of physical activity behavior change initiatives for clinicians and researchers all require a clear understanding of how to assess physical activity. In the present report, we have provided a clear rationale for the importance of assessing physical activity levels, and we have documented key concepts in understanding the different dimensions, domains, and terminology associated with physical activity measurement. The assessment methods presented allow for a greater understanding of the vast number of options available to clinicians and researchers when trying to assess physical activity levels in their patients or participants. The primary outcome desired is the main determining factor in the choice of physical activity assessment method. In combination with issues of feasibility/practicality, the availability of resources, and administration considerations, the desired outcome guides the choice of an appropriate assessment tool. The decision matrix, along with the accompanying tables, provides a mechanism for this selection that takes all of these factors into account. Clearly, the assessment method adopted and implemented will vary depending on circumstances, because there is no single best instrument appropriate for every situation. In summary, physical activity assessment should be considered a vital health measure that is tracked regularly over time. All other major modifiable cardiovascular risk factors (diabetes mellitus, hypertension, hypercholesterolemia, obesity, and smoking) are assessed routinely. Physical activity status should also be assessed regularly. Multiple physical activity assessment methods provide reasonably accurate outcome measures, with choices dependent on setting-specific resources and constraints. The present scientific statement provides a guide to

Move faster, think later: Women who play action video games have quicker visually-guided responses with later onset visuomotor-related brain activity.

Science.gov (United States)

Gorbet, Diana J; Sergio, Lauren E

2018-01-01

A history of action video game (AVG) playing is associated with improvements in several visuospatial and attention-related skills and these improvements may be transferable to unrelated tasks. These facts make video games a potential medium for skill-training and rehabilitation. However, examinations of the neural correlates underlying these observations are almost non-existent in the visuomotor system. Further, the vast majority of studies on the effects of a history of AVG play have been done using almost exclusively male participants. Therefore, to begin to fill these gaps in the literature, we present findings from two experiments. In the first, we use functional MRI to examine brain activity in experienced, female AVG players during visually-guided reaching. In the second, we examine the kinematics of visually-guided reaching in this population. Imaging data demonstrate that relative to women who do not play, AVG players have less motor-related preparatory activity in the cuneus, middle occipital gyrus, and cerebellum. This decrease is correlated with estimates of time spent playing. Further, these correlations are strongest during the performance of a visuomotor mapping that spatially dissociates eye and arm movements. However, further examinations of the full time-course of visuomotor-related activity in the AVG players revealed that the decreased activity during motor preparation likely results from a later onset of activity in AVG players, which occurs closer to beginning motor execution relative to the non-playing group. Further, the data presented here suggest that this later onset of preparatory activity represents greater neural efficiency that is associated with faster visually-guided responses.

Move faster, think later: Women who play action video games have quicker visually-guided responses with later onset visuomotor-related brain activity

Science.gov (United States)

Gorbet, Diana J.; Sergio, Lauren E.

2018-01-01

A history of action video game (AVG) playing is associated with improvements in several visuospatial and attention-related skills and these improvements may be transferable to unrelated tasks. These facts make video games a potential medium for skill-training and rehabilitation. However, examinations of the neural correlates underlying these observations are almost non-existent in the visuomotor system. Further, the vast majority of studies on the effects of a history of AVG play have been done using almost exclusively male participants. Therefore, to begin to fill these gaps in the literature, we present findings from two experiments. In the first, we use functional MRI to examine brain activity in experienced, female AVG players during visually-guided reaching. In the second, we examine the kinematics of visually-guided reaching in this population. Imaging data demonstrate that relative to women who do not play, AVG players have less motor-related preparatory activity in the cuneus, middle occipital gyrus, and cerebellum. This decrease is correlated with estimates of time spent playing. Further, these correlations are strongest during the performance of a visuomotor mapping that spatially dissociates eye and arm movements. However, further examinations of the full time-course of visuomotor-related activity in the AVG players revealed that the decreased activity during motor preparation likely results from a later onset of activity in AVG players, which occurs closer to beginning motor execution relative to the non-playing group. Further, the data presented here suggest that this later onset of preparatory activity represents greater neural efficiency that is associated with faster visually-guided responses. PMID:29364891

Activation of Visuomotor Systems during Visually Guided Movements: A Functional MRI Study

Science.gov (United States)

Ellermann, Jutta M.; Siegal, Joel D.; Strupp, John P.; Ebner, Timothy J.; Ugurbil, Kâmil

1998-04-01

The dorsal stream is a dominant visuomotor pathway that connects the striate and extrastriate cortices to posterior parietal areas. In turn, the posterior parietal areas send projections to the frontal primary motor and premotor areas. This cortical pathway is hypothesized to be involved in the transformation of a visual input into the appropriate motor output. In this study we used functional magnetic resonance imaging (fMRI) of the entire brain to determine the patterns of activation that occurred while subjects performed a visually guided motor task. In nine human subjects, fMRI data were acquired on a 4-T whole-body MR system equipped with a head gradient coil and a birdcage RF coil using aT*2-weighted EPI sequence. Functional activation was determined for three different tasks: (1) a visuomotor task consisting of moving a cursor on a screen with a joystick in relation to various targets, (2) a hand movement task consisting of moving the joystick without visual input, and (3) a eye movement task consisting of moving the eyes alone without visual input. Blood oxygenation level-dependent (BOLD) contrast-based activation maps of each subject were generated using period cross-correlation statistics. Subsequently, each subject's brain was normalized to Talairach coordinates, and the individual maps were compared on a pixel by pixel basis. Significantly activated pixels common to at least four out of six subjects were retained to construct the final functional image. The pattern of activation during visually guided movements was consistent with the flow of information from striate and extrastriate visual areas, to the posterior parietal complex, and then to frontal motor areas. The extensive activation of this network and the reproducibility among subjects is consistent with a role for the dorsal stream in transforming visual information into motor behavior. Also extensively activated were the medial and lateral cerebellar structures, implicating the cortico

Stepwise-activable multifunctional peptide-guided prodrug micelles for cancerous cells intracellular drug release

Energy Technology Data Exchange (ETDEWEB)

Zhang, Jing, E-mail: zhangjing@zjut.edu.cn; Li, Mengfei [Zhejiang University of Technology, College of Materials Science and Engineering (China); Yuan, Zhefan [Zhejiang University, Key Laboratory of Biomass Chemical Engineering of Ministry of Education, Department of Chemical and Biological Engineering (China); Wu, Dan; Chen, Jia-da; Feng, Jie, E-mail: fengjie@zjut.edu.cn [Zhejiang University of Technology, College of Materials Science and Engineering (China)

2016-10-15

A novel type of stepwise-activable multifunctional peptide-guided prodrug micelles (MPPM) was fabricated for cancerous cells intracellular drug release. Deca-lysine sequence (K{sub 10}), a type of cell-penetrating peptide, was synthesized and terminated with azido-glycine. Then a new kind of molecule, alkyne modified doxorubicin (DOX) connecting through disulfide bond (DOX-SS-alkyne), was synthesized. After coupling via Cu-catalyzed azide–alkyne cycloaddition (CuAAC) click chemistry reaction, reduction-sensitive peptide-guided prodrug was obtained. Due to the amphiphilic property of the prodrug, it can assemble to form micelles. To prevent the nanocarriers from unspecific cellular uptake, the prodrug micelles were subsequently modified with 2,3-dimethyl maleic anhydride to obtain MPPM with a negatively charged outer shell. In vitro studies showed that MPPM could be shielded from cells under psychological environment. However, when arriving at mild acidic tumor site, the cell-penetrating capacity of MPPM would be activated by charge reversal of the micelles via hydrolysis of acid-labile β-carboxylic amides and regeneration of K{sub 10}, which enabled efficient internalization of MPPM by tumor cells as well as following glutathione- and protease-induced drug release inside the cancerous cells. Furthermore, since the guide peptide sequences can be accurately designed and synthesized, it can be easily changed for various functions, such as targeting peptide, apoptotic peptide, even aptamers, only need to be terminated with azido-glycine. This method can be used as a template for reduction-sensitive peptide-guided prodrug for cancer therapy.Graphical abstractA novel type of stepwise-activable multifunctional peptide-guided prodrug micelles (MPPM) was fabricated for selective drug delivery in cancerous cells. MPPM could be shielded from cells under psychological environment. However, when arriving at mild acidic tumor site, the cell-penetrating capacity of MPPM would

Rockets: An Educator's Guide with Activities in Science, Mathematics, and Technology.

Science.gov (United States)

National Aeronautics and Space Administration, Washington, DC.

This educational guide discusses rockets and includes activities in science, mathematics, and technology. It begins with background information on the history of rocketry, scientific principles, and practical rocketry. The sections on scientific principles and practical rocketry focus on Sir Isaac Newton's Three Laws of Motion. These laws explain…

A Marketing and Distribution Curriculum Guide.

Science.gov (United States)

Freedman, Carol

This curriculum guide in marketing and distribution has been designed for children in grades K-6. It is presented much like a cookbook from which recipes (activities) may be extracted and experimented with depending on the tastes (needs) of the children. It is suggested that objectives be reinforced through teacher-developed activities or through…

Criticality safety basics, a study guide

Energy Technology Data Exchange (ETDEWEB)

V. L. Putman

1999-09-01

This document is a self-study and classroom guide, for criticality safety of activities with fissile materials outside nuclear reactors. This guide provides a basic overview of criticality safety and criticality accident prevention methods divided into three parts: theory, application, and history. Except for topic emphasis, theory and history information is general, while application information is specific to the Idaho National Engineering and Environmental Laboratory (INEEL). Information presented here should be useful to personnel who must know criticality safety basics to perform their assignments safely or to design critically safe equipment or operations. However, the guide's primary target audience is fissile material handler candidates.

Criticality safety basics, a study guide

International Nuclear Information System (INIS)

Putman, V.L.

1999-01-01

This document is a self-study and classroom guide, for criticality safety of activities with fissile materials outside nuclear reactors. This guide provides a basic overview of criticality safety and criticality accident prevention methods divided into three parts: theory, application, and history. Except for topic emphasis, theory and history information is general, while application information is specific to the Idaho National Engineering and Environmental Laboratory (INEEL). Information presented here should be useful to personnel who must know criticality safety basics to perform their assignments safely or to design critically safe equipment or operations. However, the guide's primary target audience is fissile material handler candidates

Antibacterial assay-guided isolation of active compounds from Artocarpus heterophyllus heartwoods.

Science.gov (United States)

Septama, Abdi Wira; Panichayupakaranant, Pharkphoom

2015-01-01

Preparations from Artocarpus heterophyllus Lam. (Moraceae) heartwoods are used in the traditional folk medicine for the treatment of inflammation, malarial fever, and to prevent bacterial and fungal infections. The objective of this study was to isolate pure antibacterial compounds from A. heterophyllus heartwoods. The dried and powdered A. heterophyllus heartwoods were successively extracted with the following solvents: hexane, ethyl acetate, and methanol. Each of the extracts was screened for their antibacterial activities using a disc diffusion method (10 mg/disc). Their minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were determined using a broth microdilution method. The extract that showed the strongest antibacterial activities was fractionated to isolate the active compounds by an antibacterial assay-guided isolation process. The ethyl acetate extract exhibited the strongest antibacterial activities against Streptococcus mutans, S. pyogenes, and Bacillus subtilis with MIC values of 78, 39, and 9.8 µg/mL, respectively. Based on an antibacterial assay-guided isolation, four antibacterial compounds: cycloartocarpin (1), artocarpin (2), artocarpanone (3), and cyanomaclurin (4) were purified. Among these isolated compounds, artocarpin exhibited the strongest antibacterial activity against Gram-positive bacteria, including S. mutans, S. pyogenes, B. subtilis, Staphylococcus aureus, and S. epidermidis with MICs of 4.4, 4.4, 17.8, 8.9, and 8.9 µM, respectively, and MBCs of 8.9, 8.9, 17.8, 8.9, and 8.9 µM, respectively, while artocarpanone showed the strongest activity against Escherichia coli, a Gram-negative bacteria with MIC and MBC values of 12.9 and 25.8 µM, respectively. Only artocarpin showed inhibitory activity against Pseudomonas aeruginosa with an MIC of 286.4 µM.

T & I--Electric Motors. Kit No. 621. Instructor's Manual and Student Learning Activity Guide.

Science.gov (United States)

Bomar, William

This instructor's manual and student learning activity guide comprise a kit for trade and industrial education (T & I) activities on electric motors. Purpose stated for the activities is to teach the student the four basic types of electric motors, the advantages and disadvantages of each, the types of jobs each can perform, and how to disassemble…

77 FR 70846 - Regulatory Guide 1.182, “Assessing and Managing Risk Before Maintenance Activities at Nuclear...

Science.gov (United States)

2012-11-27

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0285] Regulatory Guide 1.182, ``Assessing and Managing Risk Before Maintenance Activities at Nuclear Power Plants'' AGENCY: Nuclear Regulatory Commission... withdrawing Regulatory Guide (RG)1.182, Revision (Rev.) 0, ``Assessing and Managing Risk Before Maintenance...

All "Trashed" Out: An Activity Guide to Solid Waste Management for Grades K-6.

Science.gov (United States)

Illinois Univ., Springfield. Center for Solid Waste Management and Research, Springfield.

This activity guide, specifically designed for Illinois classrooms but adaptable for other states, seeks to encourage primary students to make their own personal statement and responses to the environment through increased awareness of reducing, reusing, recycling, and composting of solid waste materials. The activities incorporate environmental…

Rare & Endangered Species: Understanding Our Disappearing Plants and Animals. Activities Guide.

Science.gov (United States)

American Gas Association, Arlington, VA. Educational Services.

About 464 plants and animals found in the United States and its territories are listed by the U.S. Fish and Wildlife Service as threatened or endangered. Another 3900 are candidates for protection. The activities in this guide are designed to help teachers and students understand the issue of endangered species. It includes ideas for several…

Social Participation, a guide for counsellors in social activation, reintegration in the labour market and active assistance

NARCIS (Netherlands)

Henk Spies; drs. Johny Vanschoren

2005-01-01

This book contains a practical description of a successful method to guide people that have been standing in the sideline for long periods of time, to them a fitting form of social participation. This can be done through paid or voluntary work, activities aimed at physical or psychological and

CERN honours its guides

CERN Multimedia

2004-01-01

At the end of January, CERN's guides were rewarded for their devotion to the Laboratory. They have a passion for their work, know CERN inside-out and for 40 years have shown people of all ages and nationalities, from all walks of life, around the Laboratory. Who are they? Why, the CERN guides, of course. On 27 January, ten of CERN's 180 guides received special honours for their impressive number of guided tours in 2003. Presenting the awards in the Microcosm hall, CERN's Director-General Robert Aymar congratulated the winners on the key role they play with respect to the general public. "CERN would be nothing without you who show them its activities," he stressed. CERN's Director-General Robert Aymar congratulates Alberto Ribon for his tally of over 40 visits in the course of 2003.One of the prizes was the book «The Particle Odyssey». Here the book's co-author Christine Sutton dedicates it for Sijin Qian. Tzanko Spassoff (PH) and retired staff members Klaus Batzner and Antonio Francano wo...

Improving Physical Activity Resource Guides to Bridge the Divide Between the Clinic and the Community

OpenAIRE

Seligman, Hilary K.; Grossman, Melanie D.; Bera, Nathalie; Stewart, Anita L.

2008-01-01

Introduction Primary care providers have limited time for physical activity counseling. They can optimize counseling time by referring patients to community resources for more comprehensive support. To facilitate referrals, resource guides (lists of community opportunities with descriptive information) are often created but seldom used. We elicited the detailed opinions of providers about how to make resource guides more useful for them. Methods We asked a convenience sample of health care pr...

PFP functional development planning guide

International Nuclear Information System (INIS)

SINCLAIR, J.C.

1999-01-01

The PFP Functional Development Planning Guide presents the strategy and process used for the identification, development, and analysis of functions (activities) necessary to satisfy the requirements within the Plutonium Finishing Plant (PFP) integrated project baseline. The functional analysis will provide the basis for the development of a function driven work breakdown structure. Future revisions to this document will include as attachments the results of the PFP Functional Analysis resulting from this approach. This document is intended be a Project-owned management tool. As such, the guide will periodically require revisions resulting from improvements of the information, processes, and techniques as now described

Physical activity guides for Canadians: messaging strategies, realistic expectations for change, and evaluation.

Science.gov (United States)

Brawley, Lawrence R; Latimer, Amy E

2007-01-01

Physical activity guidelines offer evidence-based behavioural benchmarks that relate to reduced risk of morbidity and mortality if people adhere to them. Essentially, the guidelines tell people what to do, but not why and how they should do it. Thus, to motivate adherence, messages that translate guidelines should convey not only how much physical activity one should attempt and why it is recommended, but also how to achieve such a recommendation. Canada's physical activity guides exemplify how guidelines can be translated. This paper (i) provides a brief overview of the challenges encountered in creating the existing guides and (ii) highlights important practical issues and empirical evidence that should be considered in the future when translating guidelines into messages and disseminating these messages. We draw on the successes of past efforts to translate the goals of physical activity guidelines and on recent literature on messages and media campaigns to make recommendations. Information to motivate people to move toward the goals in physical activity guidelines should be translated into a set of messages that are informative, thought provoking, and persuasive. These messages should be disseminated to the public via a multi-phase social-marketing campaign that is carefully planned and thoroughly evaluated.

Open-ended versus guided laboratory activities:Impact on students' beliefs about experimental physics

Science.gov (United States)

Wilcox, Bethany R.; Lewandowski, H. J.

2016-12-01

Improving students' understanding of the nature of experimental physics is often an explicit or implicit goal of undergraduate laboratory physics courses. However, lab activities in traditional lab courses are typically characterized by highly structured, guided labs that often do not require or encourage students to engage authentically in the process of experimental physics. Alternatively, open-ended laboratory activities can provide a more authentic learning environment by, for example, allowing students to exercise greater autonomy in what and how physical phenomena are investigated. Engaging in authentic practices may be a critical part of improving students' beliefs around the nature of experimental physics. Here, we investigate the impact of open-ended activities in undergraduate lab courses on students' epistemologies and expectations about the nature of experimental physics, as well as their confidence and affect, as measured by the Colorado Learning Attitudes about Science Survey for Experimental Physics (E-CLASS). Using a national data set of student responses to the E-CLASS, we find that the inclusion of some open-ended lab activities in a lab course correlates with more expertlike postinstruction responses relative to courses that include only traditional guided lab activities. This finding holds when examining postinstruction E-CLASS scores while controlling for the variance associated with preinstruction scores, course level, student major, and student gender.

Actively Teaching Research Methods with a Process Oriented Guided Inquiry Learning Approach

Science.gov (United States)

Mullins, Mary H.

2017-01-01

Active learning approaches have shown to improve student learning outcomes and improve the experience of students in the classroom. This article compares a Process Oriented Guided Inquiry Learning style approach to a more traditional teaching method in an undergraduate research methods course. Moving from a more traditional learning environment to…

Elementary Environmental Activities.

Science.gov (United States)

Larson, Robert J.

This guide presents suggestions for field trips, out-of-doors activities, material for centers, and individualized activities in the teaching of elementary school science and particularly environmental education at the elementary level. The guide includes a section on preparation and procedures for conducting field trips, including sample…

Evaluation of the in vitro Anti-inflammatory Activity of Nerium oleander L. Flower Extracts and Activity-Guided Isolation of the Active Constituents

Directory of Open Access Journals (Sweden)

İrem Atay Balkan

2018-03-01

Full Text Available The in vitro anti-inflammatory activity profile of the Nerium oleander flower EtOH extract/its subextracts (n-hexane, CH 2Cl 2, EtOAc, remaining H 2O were evaluated on LPS induced Raw 264.7 macrophages. The effects of the crude EtOH extract and its subextracts on nitric oxide (NO production and cell viability were determined. The most active subextract was determined to be the EtOAc subextract without exerting any toxicity towards Raw 264.7 macrophages. This subextract significantly inhibited NO production of Raw 264.7 macrophages after LPS induction (62.56±1.91% at 200 µg/mL concentration. The levels of iNOS were reduced up to 67.50%. Moreover, this subextract slightly reduced the phosphorylation levels of MAP kinases (p-ERK, p-JNK, p-38. The highest inhibition was observed for ERK phosphorylation, which was inhibited by 20.53% at 200 µg/mL concentration. Through activity-guided fractionation procedures, kaempferol, kaempferol 3-O-β-glucopyranoside and chlorogenic acid were isolated as the main active components. The structures of the active compounds were determined by 2D-NMR techniques and HRMS analysis. All compounds significantly inhibited NO productions. Results of the present study supported the traditional use of N. oleander flowers to treat inflammatory complaints.

Phytochemical Study of Tapirira guianensis Leaves Guided by Vasodilatory and Antioxidant Activities

Directory of Open Access Journals (Sweden)

Amélia M. G. Rodrigues

2017-02-01

Full Text Available The aim of this research was to perform a phytochemical study of the methanol leaves extract of T. guianensis (MET guided by vasodilatory and antioxidant activities. The chemical profile of MET and the ethyl acetate fraction (EA fraction was determined by HPLC-UV-MS and EA fraction guided fractionation by reverse-phase chromatography. The vasorelaxant effects of MET, fractions, sub-fractions and constituents were assessed on rat aorta pre-contracted with phenylephrine. Antioxidant activity was evaluated by using a DPPH assay. The results show that MET-induced vasodilation was dependent on NO/cGMP; and that the PI3K/Akt pathway seems to be the main route involved in eNOS activation. The EA fraction showed greater vasodilatory and antioxidant potency and was submitted to further fractionation. This allowed the isolation and characterization of quercetin, quercetin 3-O-(6″-O-galloyl-β-d-galactopyranoside and 1,4,6-tri-O-galloyl-β-d-glucose. Also, galloyl-HHDP-hexoside and myricetin deoxyhexoside were identified by HPLC-UV-MS. These compounds are being described for the first time for T. guianensis. 1,4,6-tri-O-galloyl-β-d-glucose and quercetin 3-O-(6″-O-galloyl-β-d-galactopyranoside showed no vasodilatory activity. Quercetin and myricetin glycoside seems to contribute to the MET activity, since they have been reported as vasodilatory flavonoids. MET-induced vasodilation could contribute to the hypotensive effect of T. guianensis previously reported.

Field dose radiation determination by active learning with Gaussian Process for autonomous robot guiding

International Nuclear Information System (INIS)

Freitas Naiff, Danilo de; Silveira, Paulo R.; Pereira, Claudio M.N.A.

2017-01-01

This article proposes an approach for determination of radiation dose pro le in a radiation-susceptible environment, aiming to guide an autonomous robot in acting on those environments, reducing the human exposure to dangerous amount of dose. The approach consists of an active learning method based on information entropy reduction, using log-normally warped Gaussian Process (GP) as surrogate model, resulting in non-linear online regression with sequential measurements. Experiments with simulated radiation dose fields of varying complexity were made, and results showed that the approach was effective in reconstruct the eld with high accuracy, through relatively few measurements. The technique was also shown some robustness in presence measurement noise, present in real measurements, by assuming Gaussian noise. (author)

Field dose radiation determination by active learning with Gaussian Process for autonomous robot guiding

Energy Technology Data Exchange (ETDEWEB)

Freitas Naiff, Danilo de; Silveira, Paulo R.; Pereira, Claudio M.N.A., E-mail: danilonai1992@poli.ufrj.br, E-mail: paulo@lmp.ufrj.br, E-mail: cmnap@ien.gov.br [Coordenacao de Pos-Graduacao e Pesquisa de Engenharia (PEN/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil); Instituto de Engenharia Nuclear (IEN/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

2017-11-01

This article proposes an approach for determination of radiation dose pro le in a radiation-susceptible environment, aiming to guide an autonomous robot in acting on those environments, reducing the human exposure to dangerous amount of dose. The approach consists of an active learning method based on information entropy reduction, using log-normally warped Gaussian Process (GP) as surrogate model, resulting in non-linear online regression with sequential measurements. Experiments with simulated radiation dose fields of varying complexity were made, and results showed that the approach was effective in reconstruct the eld with high accuracy, through relatively few measurements. The technique was also shown some robustness in presence measurement noise, present in real measurements, by assuming Gaussian noise. (author)

IEA Implementing Agreements and Annexes: A Guide for Building Technologies Program Managers

Energy Technology Data Exchange (ETDEWEB)

Evans, Meredydd; Meier, Alan; Runci, Paul J.

2008-08-05

This guide presents insights and guidance from DOE’s gathered through longstanding and extensive participation in IEA implementing agreements (IAs) and annexes. Even though DOE has been a key participant in international research activities through the IEA since the 1970s, the experience, knowledge, and institutional memory associated with these activities can be lost or forgotten easily as key DOE managers retire or leave the department. The guide seeks to assemble in a single reference some of the learning that has occurred through participation in IEA IAs as a guide for BTP managers currently responsible for IAs and for those who might consider entering into new IEA activities in the future.

Assisting in Radiology/Imaging. Instructor's Guide, Student's Manual, and Student Learning Activities.

Science.gov (United States)

Fair, Helena J.

The instructor's guide, the first of three documents in this package, is designed for a course to help students who are investigating the activities within a radiology department or considering any of the imaging technologies as a career. The material is designed to relate training experience to information studied in the classroom. This…

Field Guides Made Easy. 4-H Leader's Guide L-5-21.

Science.gov (United States)

Phillips, Diane Held; Krasny, Marianne E.

This illustrated leader's guide describes activities for teaching children to use field guides to identify trees and birds. Background information for leaders explains the two types of field guides, those that use a series of steps in what is called a key to identify things in nature, such as trees, and those that use groupings based on…

Teens Working: Turning Earning into Learning. Facilitator Guide [and] Critical Workplace Issues [and] Student Guide.

Science.gov (United States)

Northwest Regional Educational Lab., Portland, OR. Education, Career, and Community Program.

These guides are part of a toolkit designed to help young people make connections between the jobs they now hold, the classes they are taking, and the goals they may have for the near and distant future. The guides contain a variety of materials and activities appropriate for all skill levels. The activities in the student guide are grounded in…

An Active System for Visually-Guided Reaching in 3D across Binocular Fixations

Directory of Open Access Journals (Sweden)

Ester Martinez-Martin

2014-01-01

Full Text Available Based on the importance of relative disparity between objects for accurate hand-eye coordination, this paper presents a biological approach inspired by the cortical neural architecture. So, the motor information is coded in egocentric coordinates obtained from the allocentric representation of the space (in terms of disparity generated from the egocentric representation of the visual information (image coordinates. In that way, the different aspects of the visuomotor coordination are integrated: an active vision system, composed of two vergent cameras; a module for the 2D binocular disparity estimation based on a local estimation of phase differences performed through a bank of Gabor filters; and a robotic actuator to perform the corresponding tasks (visually-guided reaching. The approach’s performance is evaluated through experiments on both simulated and real data.

Human factors guides

International Nuclear Information System (INIS)

Penington, J.

1995-10-01

This document presents human factors guides, which have been developed in order to provide licensees of the AECB with advice as to how to address human factors issues within the design and assessment process. This documents presents the results of a three part study undertaken to develop three guides which are enclosed in this document as Parts B, C and D. As part of the study human factors standards, guidelines, handbooks and other texts were researched, to define those which would be most useful to the users of the guides and for the production of the guides themselves. Detailed specifications were then produced to outline the proposed contents and format of the three guides. (author). 100 refs., 3 tabs., 11 figs

Human factors guides

Energy Technology Data Exchange (ETDEWEB)

Penington, J [PHF Services Inc., (Canada)

1995-10-01

This document presents human factors guides, which have been developed in order to provide licensees of the AECB with advice as to how to address human factors issues within the design and assessment process. This documents presents the results of a three part study undertaken to develop three guides which are enclosed in this document as Parts B, C and D. As part of the study human factors standards, guidelines, handbooks and other texts were researched, to define those which would be most useful to the users of the guides and for the production of the guides themselves. Detailed specifications were then produced to outline the proposed contents and format of the three guides. (author). 100 refs., 3 tabs., 11 figs.

Make your own video with ActivePresenter

CERN Document Server

CERN. Geneva

2016-01-01

A step-by-step video tutorial on how to use ActivePresenter, a screen recording tool for Windows and Mac. The installation step is not needed for CERN users, as the product is already made available. This tutorial explains how to install ActivePresenter, how to do a screen recording and edit a video using ActivePresenter and finally how to exports the end product. Tell us what you think about this or any other video in this category via e-learning.support at cern.ch All info about the CERN rapid e-learning project is linked from http://twiki.cern.ch/ELearning  

Nuclear safety guide TID-7016 Revision 2

International Nuclear Information System (INIS)

Thomas, J.T.

1980-01-01

The present revision of TID-7016 Nuclear Safety Guide is discussed. This Guide differs significantly from its predecessor in that the latter was intentionally conservative in its recommendations. Firmly based on experimental evidence of criticality, the original Guide and the first revision were considered to be of most value to organizations whose activities with fissionable materials were not extensive and, secondarily, that it would serve as a point of departure for members of established nuclear safety teams, experienced in the field. The reader will find a significant change in the character of information presented in this version. Nuclear Criticality Safety has matured in the past twelve years. The advance of calculational capability has permitted validated calculations to extend and substitute for experimental data. The broadened data base has enabled better interpolation, extension, and understanding of available, information, especially in areas previously addressed by undefined but adequate factors of safety. The content has been thereby enriched in qualitative guidance. The information inherently contains, and the user can recapture, the quantitative guidance characteristic of the former Guides by employing appropriate safety factors. In fact, it becomes incumbent on the Criticality Safety Specialist to necessarily impose safety factors consistent with the possible normal and abnormal credible contingencies of an operation as revealed by his evaluation. In its present form the Guide easily becomes a suitable module in any compendium or handbook tailored for internal use by organizations. It is hoped the Guide will continue to serve immediate needs and will encourage continuing and more comprehensive efforts toward organizing nuclear criticality safety information

Graphic Arts--Offset Press Operator/Duplicating Machine. TI-622. Instructor's Manual and Student Learning Activity Guide.

Science.gov (United States)

Michelsen, Robert F.

This instructor's manual and student learning activity guide comprise a kit for a graphic arts activity on offset press operator/duplicating machine. Purpose stated for the activity is to provide the student with an understanding of the basic operation involved in the production of printed matter in the graphic communications industry through the…

Open-Ended versus Guided Laboratory Activities: Impact on Students' Beliefs about Experimental Physics

Science.gov (United States)

Wilcox, Bethany R.; Lewandowski, H. J.

2016-01-01

Improving students' understanding of the nature of experimental physics is often an explicit or implicit goal of undergraduate laboratory physics courses. However, lab activities in traditional lab courses are typically characterized by highly structured, guided labs that often do not require or encourage students to engage authentically in the…

Supporting Adaptive and Adaptable Hypermedia Presentation Semantics

NARCIS (Netherlands)

D.C.A. Bulterman (Dick); L. Rutledge (Lloyd); L. Hardman (Lynda); J.R. van Ossenbruggen (Jacco)

1999-01-01

textabstractHaving the content of a presentation adapt to the needs, resources and prior activities of a user can be an important benefit of electronic documents. While part of this adaptation is related to the encodings of individual data streams, much of the adaptation can/should be guided by the

Curriculum development for the workplace using Entrustable Professional Activities (EPAs): AMEE Guide No. 99.

NARCIS (Netherlands)

ten Cate, TJ; Chen, H.C.; Hoff, RG; Peters, H.; Bok, H.; van der Schaaf, M.F.

2015-01-01

This Guide was written to support educators interested in building a competency-based workplace curriculum. It aims to provide an up-to-date overview of the literature on Entrustable Professional Activities (EPAs), supplemented with suggestions for practical application to curriculum construction,

Curriculum development for the workplace using Entrustable Professional Activities (EPAs) : AMEE Guide No. 99

NARCIS (Netherlands)

ten Cate, Th.J.; Chen, Huiju Carrie; Hoff, Reinier; Bok, Harold|info:eu-repo/dai/nl/323072356; Peters, Harm; van der Schaaf, Marieke|info:eu-repo/dai/nl/073361917

2015-01-01

This Guide was written to support educators interested in building a competency-based workplace curriculum. It aims to provide an up-to-date overview of the literature on Entrustable Professional Activities (EPAs), supplemented with suggestions for practical application to curriculum construction,

Microgravity: Teacher's guide with activities for physical science

Science.gov (United States)

Vogt, Gregory L.; Wargo, Michael J.; Rosenberg, Carla B. (Editor)

1995-01-01

This guide is an educational tool for teachers of grades 5 through 12. It is an introduction to microgravity and its application to spaceborne laboratory experiments. Specific payloads and missions are mentioned with limited detail, including Spacelab, the International Microgravity Laboratory, and the United States Microgravity Laboratory. Activities for students demonstrate chemistry, mathematics, and physics applications of microgravity. Activity objectives include: modeling how satellites orbit Earth; demonstrating that free fall eliminates the local effects of gravity; measuring the acceleration environments created by different motions; using a plasma sheet to observe acceleration forces that are experienced on board a space vehicle; demonstrating how mass can be measured in microgravity; feeling how inertia affects acceleration; observing the gravity-driven fluid flow that is caused by differences in solution density; studying surface tension and the fluid flows caused by differences in surface tension; illustrating the effects of gravity on the burning rate of candles; observing candle flame properties in free fall; measuring the contact angle of a fluid; illustrating the effects of gravity and surface tension on fiber pulling; observing crystal growth phenomena in a 1-g environment; investigating temperature effects on crystal growth; and observing crystal nucleation and growth rate during directional solidification. Each activity includes a background section, procedure, and follow-up questions.

Community Living Skills Guide: Additional Activities for Nutrition, Cooking, Homemaking, and Family Living.

Science.gov (United States)

Nickovich, Marti; Kreps, Alice Roelofs

These activities are intended to supplement materials for three courses available in the Community Living Skills Guide for the College for Living series: Cooking/Food Preparation (CE 024 475), Homemaking and Family Living (CE 024 477), and Nutrition (CE 024 484). These courses for developmentally disabled adults are intended to supplement…

The Dynamic Density Bottle: A Make-and-Take, Guided Inquiry Activity on Density

Science.gov (United States)

Kuntzleman, Thomas S.

2015-01-01

An activity is described wherein students observe dynamic floating and sinking behavior of plastic pieces in various liquids. The liquids and solids are all contained within a plastic bottle; the entire assembly is called a "density bottle". After completing a series of experiments that guides students to think about the relative…

Neural Activations of Guided Imagery and Music in Negative Emotional Processing: A Functional MRI Study.

Science.gov (United States)

Lee, Sang Eun; Han, Yeji; Park, HyunWook

2016-01-01

The Bonny Method of Guided Imagery and Music uses music and imagery to access and explore personal emotions associated with episodic memories. Understanding the neural mechanism of guided imagery and music (GIM) as combined stimuli for emotional processing informs clinical application. We performed functional magnetic resonance imaging (fMRI) to demonstrate neural mechanisms of GIM for negative emotional processing when personal episodic memory is recalled and re-experienced through GIM processes. Twenty-four healthy volunteers participated in the study, which used classical music and verbal instruction stimuli to evoke negative emotions. To analyze the neural mechanism, activated regions associated with negative emotional and episodic memory processing were extracted by conducting volume analyses for the contrast between GIM and guided imagery (GI) or music (M). The GIM stimuli showed increased activation over the M-only stimuli in five neural regions associated with negative emotional and episodic memory processing, including the left amygdala, left anterior cingulate gyrus, left insula, bilateral culmen, and left angular gyrus (AG). Compared with GI alone, GIM showed increased activation in three regions associated with episodic memory processing in the emotional context, including the right posterior cingulate gyrus, bilateral parahippocampal gyrus, and AG. No neural regions related to negative emotional and episodic memory processing showed more activation for M and GI than for GIM. As a combined multimodal stimulus, GIM may increase neural activations related to negative emotions and episodic memory processing. Findings suggest a neural basis for GIM with personal episodic memories affecting cortical and subcortical structures and functions. © the American Music Therapy Association 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Nuclear safety guide. TID-7016, Revision 2

International Nuclear Information System (INIS)

Thomas, J.T.

1978-01-01

The Nuclear Safety Guide was first issued in 1956 as classified AEC report LA-2063 and was reprinted the next year, unclassified, as TID-7016. Revision 1, published in 1961, extended the scope and refined the guiding information. The present revision of the Guide differs significantly from its predecessor in that the latter was intentionally conservative in its recommendations. Firmly based on experimental evidence of criticality, the original Guide and the first revision were considered to be of most value to organizations whose activities with fissionable materials were not extensive and, secondarily, that it would serve as a point of departure for members of established nuclear safety teams, experienced in the field. The reader will find a significant change in the character of information presented in this version. Nuclear Criticality Safety has matured in the past twelve years. The advance of calculational capability has permitted validated calculations to extend and substitute for experimental data. The broadened data base has enabled better interpolation, extension, and understanding of available information, especially in areas previously addressed by undefined but adequate factors of safety. The content has been thereby enriched in qualitative guidance. The information inherently contains, and the user can recapture, the quantitative guidance characteristic of the formerGuides by employing appropriate safety factors. In fact, it becomes incumbent on the Criticality Safety Specialist to necessarily impose safety factors consistent with the possible normal and abnormal credible contingencies of an operation as revealed by his evaluation. In its present form the Guide easily becomes a suitable module in any compendium or handbook tailored for internal use by organizations. It is hoped the Guide will continue to serve immediate needs and will encourage continuing and more comprehensive efforts toward organizing nuclear criticality safety information

Nuclear safety guide. TID-7016, Revision 2

Energy Technology Data Exchange (ETDEWEB)

Thomas, J T [ed.

1978-05-01

The Nuclear Safety Guide was first issued in 1956 as classified AEC report LA-2063 and was reprinted the next year, unclassified, as TID-7016. Revision 1, published in 1961, extended the scope and refined the guiding information. The present revision of the Guide differs significantly from its predecessor in that the latter was intentionally conservative in its recommendations. Firmly based on experimental evidence of criticality, the original Guide and the first revision were considered to be of most value to organizations whose activities with fissionable materials were not extensive and, secondarily, that it would serve as a point of departure for members of established nuclear safety teams, experienced in the field. The reader will find a significant change in the character of information presented in this version. Nuclear Criticality Safety has matured in the past twelve years. The advance of calculational capability has permitted validated calculations to extend and substitute for experimental data. The broadened data base has enabled better interpolation, extension, and understanding of available information, especially in areas previously addressed by undefined but adequate factors of safety. The content has been thereby enriched in qualitative guidance. The information inherently contains, and the user can recapture, the quantitative guidance characteristic of the formerGuides by employing appropriate safety factors. In fact, it becomes incumbent on the Criticality Safety Specialist to necessarily impose safety factors consistent with the possible normal and abnormal credible contingencies of an operation as revealed by his evaluation. In its present form the Guide easily becomes a suitable module in any compendium or handbook tailored for internal use by organizations. It is hoped the Guide will continue to serve immediate needs and will encourage continuing and more comprehensive efforts toward organizing nuclear criticality safety information.

Lathe Operator. Coordinator's Guide. Individualized Study Guide. General Metal Trades.

Science.gov (United States)

East Texas State Univ., Commerce. Occupational Curriculum Lab.

This guide provides information to enable coordinators to direct learning activities for students using an individualized study guide on operating a lathe. The study material is designed for students enrolled in cooperative part-time training and employed, or desiring to be employed, as lathe operators. Contents include a sample progress chart,…

3...2...1...Liftoff!: An Educator's Guide with Activities in Science, Mathematics, Technology, and Language Arts.

Science.gov (United States)

National Aeronautics and Space Administration, Washington, DC.

This curriculum supplement introduces students in the early childhood classroom to the International Space Station and the role rockets play in its construction. The guide uses these topics as the basis for interdisciplinary activities for the early learner. Each activity features objectives, a material list, educator information, procedures, and…

Guided-wave acousto-optics interactions, devices, and applications

CERN Document Server

1990-01-01

The field of integrated- or guided-wave optics has experienced significant and continuous growth since its inception in the late 1960s. There has been a considerable increase in research and development activity in this field worldwide and some significant advances in the realization of working in­ tegrated optic devices and modules have been made in recent years. In fact, there have already been some commercial manufacturing and technical ap­ plications of such devices and modules. The guided-wave-acoustooptics involving Bragg interactions between guided optical waves and surface acoustic waves is one of the areas of in­ tegrated-optics that has reached some degree of scientific and technological maturity. This topical volume is devoted to an in-depth treatment of this emerging branch of science and technology. Presented in this volume are concise treatments on bulk-wave acoustooptics, guided-wave optics, and surface acoustic waves, and detailed studies of guided-wave acoustooptic Bragg diffraction in thr...

Guide to the collection and presentation of electrical, electronic, and sensing component reliability data for nuclear-power generating stations

International Nuclear Information System (INIS)

Anon.

1979-01-01

This Guide is intended to establish a method of collecting and presenting reliability data for quantitative systematic reliability analysis in nuclear power generating stations, as outlined in IEEE Std 351-1975. Appendix D, which is not a part of IEEE Std 500-1977 but which comprises the bulk of this publication, presents tables of reliability data for nuclear power generating stations, intended for use of nuclear systems reliability analysts or design engineers

The Explicit Instruction of Reading Strategies: Directed Reading Thinking Activity vs. Guided Reading Strategies

Directory of Open Access Journals (Sweden)

Mohammad Mehdi Yazdani

2015-05-01

Full Text Available Investigating the efficiencies and deficiencies of reading strategies is one of the noticeable issues in the related theory and research in reading comprehension instruction. This study was to examine the impact of Directed Reading Thinking Activity (DRTA and Guided Reading (GR on reading comprehension. Sixty three Iranian students of grade one in Shahed high school in the city of Bojnourd took part in the study. They were assigned in three groups, one control and two experimental groups. The instruction lasted for ten weeks. This study utilized a pretest posttest control group in quantitative quasi- experimental design. The same reading comprehension test was administered as pre-test and post-test. The results were twofold: First, the instruction of learning strategies could foster reading comprehension skill. Second, while the explicit instruction of both strategies could improve the students' reading comprehension skill, Directed Reading Thinking Activity had a more significant positive effect than Guided Reading.

GuideLiner™ as guide catheter extension for the unreachable mammary bypass graft.

Science.gov (United States)

Vishnevsky, Alec; Savage, Michael P; Fischman, David L

2018-03-09

Percutaneous coronary intervention (PCI) of mammary artery bypass grafts through a trans-radial (TR) approach can present unique challenges, including coaxial vessel engagement of the guiding catheter, adequate visualization of the target lesion, sufficient backup support for equipment delivery, and the ability to reach very distal lesions. The GuideLiner catheter, a rapid exchange monorail mother-in-daughter system, facilitates successful interventions in such challenging anatomy. We present a case of a patient undergoing PCI of a right internal mammary artery (RIMA) graft via TR access in whom the graft could not be engaged with any guiding catheter. Using a balloon tracking technique over a guidewire, a GuideLiner was placed as an extension of the guiding catheter and facilitated TR-PCI by overcoming technical challenges associated with difficult anatomy. © 2018 Wiley Periodicals, Inc.

Guide to hazardous industrial activities: handbook for the cataloguing and selection of industrial activities for which an Emergency Management Plan ought to be drafted

NARCIS (Netherlands)

Ham, J.M.; Blom-Bruggeman, J.M.

1989-01-01

A methodology has been developed for the cataloguing of hazardous (industrial) activities and the evaluation of these activities as part of the process of formulating an emergency management plan. This guide will enable priorities to be set at local level (district, region) for the drafting of

HBR guides

CERN Document Server

Duarte, Nancy; Dillon, Karen

2015-01-01

Master your most pressing professional challenges with this seven-volume set that collects the smartest best practices from leading experts all in one place. "HBR Guide to Better Business Writing" and "HBR Guide to Persuasive Presentations" help you perfect your communication skills; "HBR Guide to Managing Up and Across" and "HBR Guide to Office Politics" show you how to build the best professional relationships; "HBR Guide to Finance Basics for Managers" is the one book you'll ever need to teach you about the numbers; "HBR Guide to Project Management" addresses tough questions such as how to manage stakeholder expectations and how to manage uncertainty in a complex project; and "HBR Guide to Getting the Right Work Done" goes beyond basic productivity tips to teach you how to prioritize and focus on your work. This specially priced set of the most popular books in the series makes a perfect gift for aspiring leaders looking for trusted advice. Arm yourself with the advice you need to succeed on the job, from ...

Assisting Handlers Following Attacks on Dog Guides: Implications for Dog Guide Teams

Science.gov (United States)

Godley, Cheryl A.; Gillard, Marc A.

2011-01-01

Attacks by dogs on dog guides are traumatic for dog guide teams. One variable that affects a team's recovery is how handlers cope with emotional responses to the attack. This article presents a three-stage model for assisting handlers that is useful for handlers and dog guide instructors.

Office Occupations--Accounting, Payroll. Kit No. 64. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

Conner, Connie

An instructor's manual and student activity guide on payroll management are provided in this set of prevocational education materials which focuses on the vocational area of office occupations (accounting). (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings: agriculture,…

Exploring the Extreme: High Performance Learning Activities in Mathematics, Science and Technology. An Educator's Guide. EG-2002-10-001-DFRC

Science.gov (United States)

Dana, Judi; Kock, Meri; Lewis, Mike; Peterson, Bruce; Stowe, Steve

2010-01-01

The many activities contained in this teaching guide emphasize hands-on involvement, prediction, data collection and interpretation, teamwork, and problem solving. The guide also contains background information about aeronautical research that can help students learn how airplanes fly. Following the background sections are a series of activities…

T & I--Machine Shop. Kit No. 83. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

White, Jim

An instructor's manual and student activity guide on the machine shop are provided in this set of prevocational education materials which focuses on the vocational area of trade and industry. (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings: agriculture, home…

Guided Learning at Work.

Science.gov (United States)

Billett, Stephen

2000-01-01

Guided learning (questioning, diagrams/analogies, modeling, coaching) was studied through critical incident interviews in five workplaces. Participation in everyday work activities was the most effective contributor to workplace learning. Organizational readiness and the efficacy of guided learning in resolving novel tasks were also important. (SK)

Activity-Guided Identification of in Vitro Antioxidants in Beer.

Science.gov (United States)

Spreng, Stefan; Hofmann, Thomas

2018-01-24

In order to locate the key antioxidants contributing to oxidative stability of beer, activity-guided fractionation in combination with the oxygen radical absorbance capacity (ORAC) assay, hydrogen peroxide scavenging (HPS) assay, and linoleic acid (LA) assay was applied to a pilsner-type beer. LC-MS and 1D/2D NMR experiments led to the identification of a total of 31 antioxidants, among which 3-methoxy-4-hydroxyphenyl-β-d-glucopyranoside (tachioside), 4-(2-formylpyrrol-1-yl)butyric acid, 4-[2-formyl-5-(hydroxymethyl)pyrrol-1-yl]butyric acid, n-multifidol-3-O-β-d-glucoside, quercetin-3-O-(6″-malonyl)-glucoside, 4-feruloylquinic acid, syringaresinol, saponarin, and hordatines A-C have been isolated from beer for the first time. On a molar comparison, the hordatines A-C, saponarin, and quercetin-3-O-β-d-(6″-malonyl)glucoside were evaluated with the highest antioxidant activities of all identified beer constituents, reaching values of 10-17.5 (ORAC), 2.0-4.1 (HPS), and 1.1-6.1 μmol TE/μmol (LA) for hordatines A-C.

Bioassay-guided fractionation of Melastoma malabathricum Linn. leaf solid phase extraction fraction and its anticoagulant activity.

Science.gov (United States)

Khoo, Li Teng; Abdullah, Janna Ong; Abas, Faridah; Tohit, Eusni Rahayu Mohd; Hamid, Muhajir

2015-02-24

The aims of this study were to examine the bioactive component(s) responsible for the anticoagulant activity of M. malabathricum Linn. leaf hot water crude extract via bioassay-guided fractionation and to evaluate the effect of bioactive component(s) on the intrinsic blood coagulation pathway. The active anticoagulant fraction of F3 was subjected to a series of chromatographic separation and spectroscopic analyses. Furthermore, the effect of the bioactive component(s) on the intrinsic blood coagulation pathway was studied through immediate and time incubation mixing studies. Through Activated Partial Thromboplastin Time (APTT) assay-guided fractionation, Subfraction B was considered the most potent anticoagulant fraction. Characterisation of Subfraction B indicated that anticoagulant activity could partly be due to the presence of cinnamic acid and a cinnamic acid derivative. APTT assays for both the immediate and time incubation mixing were corrected back into normal clotting time range (35.4-56.3 s). In conclusion, cinnamic acid and cinnamic acid derivative from Subfraction B were the first such compounds to be discovered from M. malabathricum Linn. leaf hot water crude extract that possess anticoagulant activity. This active anticoagulant Subfraction B prolonged blood clotting time by causing factor(s) deficiency in the intrinsic blood coagulation pathway.

Mechanism-Guided Discovery of an Esterase Scaffold with Promiscuous Amidase Activity

Directory of Open Access Journals (Sweden)

Charlotte Kürten

2016-06-01

Full Text Available The discovery and generation of biocatalysts with extended catalytic versatilities are of immense relevance in both chemistry and biotechnology. An enhanced atomistic understanding of enzyme promiscuity, a mechanism through which living systems acquire novel catalytic functions and specificities by evolution, would thus be of central interest. Using esterase-catalyzed amide bond hydrolysis as a model system, we pursued a simplistic in silico discovery program aiming for the identification of enzymes with an internal backbone hydrogen bond acceptor that could act as a reaction specificity shifter in hydrolytic enzymes. Focusing on stabilization of the rate limiting transition state of nitrogen inversion, our mechanism-guided approach predicted that the acyl hydrolase patatin of the α/β phospholipase fold would display reaction promiscuity. Experimental analysis confirmed previously unknown high amidase over esterase activity displayed by the first described esterase machinery with a protein backbone hydrogen bond acceptor to the reacting NH-group of amides. The present work highlights the importance of a fundamental understanding of enzymatic reactions and its potential for predicting enzyme scaffolds displaying alternative chemistries amenable to further evolution by enzyme engineering.

Destination: Marshall Islands. Video Guide.

Science.gov (United States)

Legowski, Margaret

This video guide was developed by the Peace Corps' Office of World Wise Schools. Activities that the guide describes are for use in a 3- to 5-day unit on one of the nations of Oceania, the Republic of the Marshall Islands. The activities are designed to provide students with opportunities to: (1) compare and contrast Marshallese and U.S. culture;…

Dynamic Mode Tuning of Ultrasonic Guided Wave Using an Array Transducer

International Nuclear Information System (INIS)

Kim, Young H.; Song, Sung J.; Park, Joon S.; Kim, Jae H.; Eom, Heung S.

2005-01-01

Ultrasonic guided waves have been widely employed for long range inspection of structures such as plates, rods and pipes. There are numerous modes with different wave velocities, and the appropriate mode selection is one of key techniques in the application of guided waves. In the present work, phase tuning by an array transducer was applied to generate ultrasonic guided waves. For this purpose, 8-channel ultrasonic pulser/receiver and their controller which enables sequential activation of each channels with given time delay were developed. Eight transducers were fabricated in order to generate guided waves by using an array transducer. The selective tuning of wave mode can be achieved by changing the interval between elements of an array transducer

A User's Guide to the Federal Theater Project.

Science.gov (United States)

Sheridan, Frank; Leslie, Linda

1997-01-01

Presents a lesson plan constructed around materials found in the User's Guide to the Federal Project. The Federal Theater Project produced radical and populist plays during the Great Depression before being de-funded by a conservative Congress. The lessons include activities and discussion built around the original plays. (MJP)

Suited for Spacewalking: A Teacher's Guide with Activities for Technology Education, Mathematics, and Science

Science.gov (United States)

Vogt, Gregory L.; George, Jane A. (Editor)

1998-01-01

A Teacher's Guide with Activities for Technology Education, Mathematics, and Science National Aeronautics and Space Administration Office of Human Resources and Education Education Division Washington, DC Education Working Group NASA Johnson Space Center Houston, Texas This publication is in the Public Domain and is not protected by copyright. Permission is not required for duplication.

Identification of Lilial as a fragrance sensitizer in a perfume by bioassay-guided chemical fractionation and structure-activity relationships.

Science.gov (United States)

Arnau, E G; Andersen, K E; Bruze, M; Frosch, P J; Johansen, J D; Menné, T; Rastogi, S C; White, I R; Lepoittevin, J P

2000-12-01

Fragrance materials are among the most common causes of allergic contact dermatitis. The aim of this study was to identify in a perfume fragrance allergens not included in the fragrance mix, by use of bioassay-guided chemical fractionation and chemical analysis/structure-activity relationships (SARs). The basis for the investigation was a 45-year-old woman allergic to her own perfume. She had a negative patch test to the fragrance mix and agreed to participate in the study. Chemical fractionation of the perfume concentrate was used for repeated patch testing and/or repeated open application test on the pre-sensitized patient. The chemical composition of the fractions giving a positive patch-test response and repeated open application test reactions was obtained by gas chromatography-mass spectrometry. From the compounds identified, those that contained a "structural alert" in their chemical structure, indicating an ability to modify skin proteins and thus behave as a skin sensitizer, were tested on the patient. The patient reacted positively to the synthetic fragrance p-t-butyl-alpha-methylhydrocinnamic aldehyde (Lilial), a widely used fragrance compound not present in the fragrance mix. The combination of bioassay-guided chemical fractionation and chemical analysis/structure-activity relationships seems to be a valuable tool for the investigation of contact allergy to fragrance materials.

Computer-guided laser for neurosurgery.

Science.gov (United States)

Koivukangas, J; Louhisalmi, Y

1990-01-01

On the basis of over 40 neurosurgical laser operations, including CO2, Nd-YAG and simultaneous CO2/Nd-YAG laser procedures, a computer-guided system for spatial control of the laser beam has been developed. The pilot laser has several modes: it can direct the neurosurgeon along the central axis of the surgical microscope to stereotactically determined point-like targets or outline selected layers of underlying volume targets onto superficial surfaces such as scalp and cortex and onto the tissue at the appropriate depth. The active treatment laser can be guided by preoperative CT/MRI or intraoperative ultrasound image data for layer-by-layer resection of tumor. The laser system can be connected to the surgical field by rigid stereotactic means or by neuronavigator. In the present system, a special brain surgery adapter coordinates the imaging system and laser to the surgical field. Thus, the laser system can be used for image-guided surgical orientation, for demarcation of lesions and for actual layer-by-layer removal of tumor.

Packaging supplier inspection guide

International Nuclear Information System (INIS)

Stromberg, H.M.; Gregg, R.E.; Kido, C.; Boyle, C.D.

1991-05-01

This is document is a guide for conducting quality assurance inspections of transportations packaging suppliers, where suppliers are defined as designers, fabricators, distributors, users, or owners of transportation packaging. This document can be used during an inspection to determine regulatory compliance within the requirements of 10 Code of Federal Regulations, Part 71, Subpart H (10 CFR 71.101--71.135). The guidance described in this document provides a framework for an inspection. It provides the inspector with the flexibility to adapt the methods and concepts presented here to meet the needs of the particular facility being inspected. The guide was developed to ensure a structured and consistent approach for inspections. The method treats each activity at a supplier facility as a separate entity (or functional element), and combines the activities within the framework of an ''inspection tree.'' The method separates each functional element into several areas of performance and then identifies guidelines, based on regulatory requirements, to be used to qualitatively rate each area. This document was developed to serve as a field manual to facilitate the work of inspectors. 1 ref., 1 fig., 5 tabs

Coastal Processes and Erosion, Student Guide and Teacher Guide. OEAGLS Investigation 7.

Science.gov (United States)

Kennedy, Beth A.; Fortner, Rosanne W.

This investigation focuses on the major erosional forces affecting the shoreline which cause it to wear away and build up. The types of devices that protect the shoreline are also discussed. The investigation is presented in the form of a teachers' guide and a students' guide, both of which are included. In the teachers' guide, an overview of the…

Electromagnetic ultrasonic guided waves

CERN Document Server

Huang, Songling; Li, Weibin; Wang, Qing

2016-01-01

This book introduces the fundamental theory of electromagnetic ultrasonic guided waves, together with its applications. It includes the dispersion characteristics and matching theory of guided waves; the mechanism of production and theoretical model of electromagnetic ultrasonic guided waves; the effect mechanism between guided waves and defects; the simulation method for the entire process of electromagnetic ultrasonic guided wave propagation; electromagnetic ultrasonic thickness measurement; pipeline axial guided wave defect detection; and electromagnetic ultrasonic guided wave detection of gas pipeline cracks. This theory and findings on applications draw on the author’s intensive research over the past eight years. The book can be used for nondestructive testing technology and as an engineering reference work. The specific implementation of the electromagnetic ultrasonic guided wave system presented here will also be of value for other nondestructive test developers.

IEEE guide to the collection and presentation of electrical, electronic, and sensing component reliability data for nuclear-power generating stations

International Nuclear Information System (INIS)

Anon.

1977-01-01

Guidelines are given for the purpose of establishing standardization methods for collecting and presenting reliability data for quantitative systematic analysis in nuclear power plants. This guide may be also used for reliability analysis in other segments of power industry. The data considered include failure rates, failure modes and environmental impact on component behavior

Coherent versus incoherent dynamics in InAs quantum-dot active wave guides

DEFF Research Database (Denmark)

Borri, Paola; Langbein, W.; Hvam, Jørn Märcher

2001-01-01

Coherent dynamics measured by time-resolved four-wave mixing is compared to incoherent population dynamics measured by differential transmission spectroscopy on the ground-state transition at room temperature of two types of InAs-based quantum dots with different confinement energies. The measure....... The measurements are performed with heterodyne detection on quantum-dot active wave guides to enhance the light-matter interaction length. An elastic nature of the measured dephasing is revealed which is independent of the dot energy level scheme....

Present and future of the Image Guided Radiotherapy (I.G.R.T.) and its applications in lung cancer treatment

International Nuclear Information System (INIS)

Lefkopoulos, D.; Ferreira, I.; Isambert, A.; Le Pechoux, C.; Mornex, F.

2007-01-01

These last years, the new irradiation techniques as the conformal 3D radiotherapy and the IMRT are strongly correlated with the technological developments in radiotherapy. The rigorous definition of the target volume and the organs at risk required by these irradiation techniques, imposed the development of various image guided patient positioning and target tracking techniques. The availability of these imaging systems inside the treatment room has lead to the exploration of performing real-time adaptive radiation therapy. In this paper we present the different image guided radiotherapy (IGRT) techniques and the adaptive radiotherapy (ART) approaches. IGRT developments are focused in the following areas: 1) biological imaging for better definition of tumor volume; 2) 4D imaging for modeling the intra-fraction organ motion; 3) on-board imaging system or imaging devices registered to the treatment machines for inter-fraction patient localization; and 4) treatment planning and delivery schemes incorporating the information derived from the new imaging techniques. As this paper is included in the 'Cancer Radiotherapie' special volume dedicated to the lung cancers, in the description of the different IGRT techniques we try to present the lung tumors applications when this is possible. (author)

MR-guided focused ultrasound surgery, present and future

International Nuclear Information System (INIS)

Schlesinger, David; Benedict, Stanley; Diederich, Chris; Gedroyc, Wladyslaw; Klibanov, Alexander; Larner, James

2013-01-01

MR-guided focused ultrasound surgery (MRgFUS) is a quickly developing technology with potential applications across a spectrum of indications traditionally within the domain of radiation oncology. Especially for applications where focal treatment is the preferred technique (for example, radiosurgery), MRgFUS has the potential to be a disruptive technology that could shift traditional patterns of care. While currently cleared in the United States for the noninvasive treatment of uterine fibroids and bone metastases, a wide range of clinical trials are currently underway, and the number of publications describing advances in MRgFUS is increasing. However, for MRgFUS to make the transition from a research curiosity to a clinical standard of care, a variety of challenges, technical, financial, clinical, and practical, must be overcome. This installment of the Vision 20/20 series examines the current status of MRgFUS, focusing on the hurdles the technology faces before it can cross over from a research technique to a standard fixture in the clinic. It then reviews current and near-term technical developments which may overcome these hurdles and allow MRgFUS to break through into clinical practice

MR-guided focused ultrasound surgery, present and future

Energy Technology Data Exchange (ETDEWEB)

Schlesinger, David, E-mail: djs9c@virginia.edu [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22908 and Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908 (United States); Benedict, Stanley [Department of Radiation Oncology, University of California Davis, Davis, California 95817 (United States); Diederich, Chris [Department of Radiation Oncology, University of California San Francisco, San Francisco, California 94115 (United States); Gedroyc, Wladyslaw [Department of Medicine, Imperial College, London SW7 2AZ (United Kingdom); Klibanov, Alexander [Departments of Medicine, Cardiovascular Medicine, and Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22908 (United States); Larner, James [Department of Radiation Oncology, University of Virginia, Charlottesville, Virginia 22908 (United States)

2013-08-01

MR-guided focused ultrasound surgery (MRgFUS) is a quickly developing technology with potential applications across a spectrum of indications traditionally within the domain of radiation oncology. Especially for applications where focal treatment is the preferred technique (for example, radiosurgery), MRgFUS has the potential to be a disruptive technology that could shift traditional patterns of care. While currently cleared in the United States for the noninvasive treatment of uterine fibroids and bone metastases, a wide range of clinical trials are currently underway, and the number of publications describing advances in MRgFUS is increasing. However, for MRgFUS to make the transition from a research curiosity to a clinical standard of care, a variety of challenges, technical, financial, clinical, and practical, must be overcome. This installment of the Vision 20/20 series examines the current status of MRgFUS, focusing on the hurdles the technology faces before it can cross over from a research technique to a standard fixture in the clinic. It then reviews current and near-term technical developments which may overcome these hurdles and allow MRgFUS to break through into clinical practice.

Activity-guided isolation of cytotoxic bis-bibenzyl constituents from Dumortiera hirsuta.

Science.gov (United States)

Toyota, Masao; Ikeda, Risa; Kenmoku, Hiromichi; Asakawa, Yoshinori

2013-01-01

Activity-guided fractionation of the ether extract of Dumortiera hirsute (Japanese liverwort), using cytotoxicity testing with cultured HL 60 and KB cells, resulted in the isolation of a new cytotoxic bis-bibenzyl compound, along with the two known bis-bibenzyls: isomarchantin C and isoriccardin C. The structural determination of the new bis-bibenzyl through extensive NMR spectral data indicated a derivative of marchantin A, which has been isolated from the liverwort Marchantia polymorpha. The cytotoxicity of the bis-bibenzyls was evaluated by the MTT (3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay using cultured HL 60 and KB cells.

Sex Roles, Past, Present and Future; A Guide to Simulations, Games and Activities. 2nd Edition.

Science.gov (United States)

Population Inst., Washington, DC.

This brief listing describes games, activities, awareness exercises and projects which explore the realities and myths about the nature, history and potential of men and women. Among the activities are projects designed for children and adults, for individuals, groups, clubs, couples and classes. They can be used in self-education efforts, in…

Magnetic resonance imaging guided transatrial electrophysiological studies in swine using active catheter tracking - experience with 14 cases

Energy Technology Data Exchange (ETDEWEB)

Grothoff, Matthias; Gutberlet, Matthias [University of Leipzig - Heart Center, Department of Radiology, Leipzig (Germany); Hindricks, Gerhard; Sommer, Philipp; Hilbert, Sebastian [University of Leipzig - Heart Center, Department of Electrophysiology, Leipzig (Germany); Fleiter, Christian [Helios Klinikum Berlin-Buch, Department of Orthopaedic Surgery, Berlin (Germany); Schnackenburg, Bernhard [Philips Healthcare, Hamburg (Germany); Weiss, Steffen; Krueger, Sascha [Philips Innovative Technologies, Hamburg (Germany); Piorkowski, Christopher; Gaspar, Thomas [University of Dresden - Heart Center, Department of Electrophysiology, Dresden (Germany); Wedan, Steve; Lloyd, Thomas [Imricor Medical Systems, Burnsville, MN (United States)

2017-05-15

To evaluate the feasibility of performing comprehensive Cardiac Magnetic resonance (CMR) guided electrophysiological (EP) interventions in a porcine model encompassing left atrial access. After introduction of two femoral sheaths 14 swine (41 ± 3.6 kg) were transferred to a 1.5 T MR scanner. A three-dimensional whole-heart sequence was acquired followed by segmentation and the visualization of all heart chambers using an image-guidance platform. Two MR conditional catheters were inserted. The interventional protocol consisted of intubation of the coronary sinus, activation mapping, transseptal left atrial access (n = 4), generation of ablation lesions and eventually ablation of the atrioventricular (AV) node. For visualization of the catheter tip active tracking was used. Catheter positions were confirmed by passive real-time imaging. Total procedure time was 169 ± 51 minutes. The protocol could be completed in 12 swine. Two swine died from AV-ablation induced ventricular fibrillation. Catheters could be visualized and navigated under active tracking almost exclusively. The position of the catheter tips as visualized by active tracking could reliably be confirmed with passive catheter imaging. Comprehensive CMR-guided EP interventions including left atrial access are feasible in swine using active catheter tracking. (orig.)

Career Education Instructional Guide.

Science.gov (United States)

State Univ. of New York, Oswego. Coll. at Oswego. Dept. of Industrial Arts and Technology.

The guide is designed primarily for industrial arts teachers at the middle school level who wish to integrate career education into their curricula. The lessons and activities attempt to establish a balance among career information, technical information, and hands-on experience. The guide contains six lesson plans which cover the topics: the…

Home Economics--Food Service Catering. Kit No. 54. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

Lowery, Ann

An instructor's manual and student activity guide on food service, catering are provided in this set of prevocational education materials which focuses on the vocational area of home economics. (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings: agriculture, home…

Agriculture--Agriculture Science--Seed Germination. Kit No. 51. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

Cooper, Samuel

An instructor's manual and student activity guide on seed germination are provided in this set of prevocational education materials which focuses on the vocational area of agriculture. (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings: agriculture, home economics,…

Agriculture--Agricultural Mechanics, Electric Motors. Kit No. 56. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

Bomar, William

An instructor's manual and student activity guide on agricultural mechanics (electric motors) are provided in this set of prevocational education materials which focuses on the vocational area of agriculture. (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings:…

Pocket companion to PMI's PMBOK guide

CERN Document Server

Snijders, Paul; Zandhuis, Anton

2010-01-01

This pocket guide is based on the PMBOK Guide® Fourth Edition.This pocket guide supplies a summary of the PMBOK Guide® , to provide a quick introduction as well as a structured overview of this method for project management.This pocket guide deals with the key issues and themes within project management and PMBOK:A short overview of the activities of PMI Inc., The organization and its standards: PMBOK Guide®, Standard for Project Portfolio Management, Standard for Program Management, OPM3.The essentials of the Project Lifecycle and Organization.What are the key project management knowledge ar

From an Ancient Tradition to the Present. Chinese Cultural Heritage Resource Guide.

Science.gov (United States)

Chen, Ching Fang; Lee, Amy

This cultural heritage resource guide has been prepared as a tool for teachers to help promote better understanding of Chinese students in the New York City public schools. China has an ancient history and a rich cultural tradition, and people all over the world have recognized China as one of the world's greatest civilizations. The earliest…

T & I--Cosmetology, Skin Care. Kit No. 77. Instructor's Manual [and] Student Learning Activity Guide.

Science.gov (United States)

Terry, Carolyn

An instructor's manual and student activity guide on skin care are provided in this set of prevocational education materials which focuses on the vocational area of trade and industry (cosmetology). (This set of materials is one of ninety-two prevocational education sets arranged around a cluster of seven vocational offerings: agriculture, home…

Young Children's Development of Scientific Knowledge Through the Combination of Teacher-Guided Play and Child-Guided Play

Science.gov (United States)

Sliogeris, Marija; Almeida, Sylvia Christine

2017-09-01

Play-based approaches to science learning allow children to meaningfully draw on their everyday experiences and activities as they explore science concepts in context. Acknowledging the crucial role of the teacher in facilitating science learning through play, the purpose of this qualitative study was to examine how teacher-guided play, in conjunction with child-guided play, supports children's development of science concepts. While previous research on play-based science learning has mainly focused on preschool settings, this study explores the possibilities of play-based approaches to science in primary school contexts. Using a qualitative methodology grounded in the cultural-historical theoretical perspective, children's learning was examined during a science learning sequence that combined teacher-guided and child-guided play. This study revealed that the teacher-guided play explicitly introduced science concepts which children then used and explored in subsequent child-guided play. However, intentional teaching during the child-guided play continued to be important. Play-based approaches to science allowed children to make sense of the science concepts using familiar, everyday knowledge and activities. It became evident that the expectations and values communicated through classroom practices influenced children's learning through play.

Nuclear computerized library for assessing reactor reliability (NUCLARR): Part 2, Guide to operations: User's guide

International Nuclear Information System (INIS)

Gilmore, W.E.; Gentillon, C.D.; Gertman, D.I.; Beers, G.H.; Galyean, W.J.; Gilbert, B.G.

1988-06-01

The Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR) is an automated data base management system for processing and storing human error probability and hardware component failure data. The NUCLARR system software resides on an IBM (or compatible) personal micro-computer. NUCLARR can be used by the end user to furnish data inputs for both human and hardware reliability analysis in support of a variety of risk assessment activities. The NUCLARR system is documented in a five-volume series of reports. Volume IV of this series is the User's Guide for operating the NUCLARR software and is presented in three parts. This volume, Part 2: Guide to Operations, contains the instructions and basic procedures for using the NUCLARR software. Part 2 provides guidance and information for getting started, performing the desired functions, and making the most efficient use of the system's features

Sonography-guided hydrostatic reduction of ileocolic intussusception in children: analysis of failure and success in consecutive patients presenting timely to the hospital.

Science.gov (United States)

Menke, Jan; Kahl, Fritz

2015-03-01

In children with ileocolic intussusception sonography is increasingly being used for diagnosis, whereas fluoroscopy is frequently used for guiding non-invasive reduction. This study assessed the success rate of radiation-free sonography-guided hydrostatic reduction in children with ileocolic intussusception, using novel well-defined success rate indices. All children were evaluated who presented from 2005 to 2013 to the local university hospital with ileocolic intussusception. The patients were treated with sonography-guided hydrostatic reduction unless primary surgery was clinically indicated. The according success rate was determined by indices of Bekdash et al. They represent the ratio of persistently successful non-surgical reductions versus four different denominators, depending on including/excluding cases with primary surgery and including/excluding cases requiring bowel resection/intervention. Fifty-six consecutive patients were included (age, 3 months to 7.8 years). About 80% of the patients presented until 24 h and 20% until 48 h after the onset of symptoms. Seven patients underwent primary surgery, with bowel resection required in three cases. Hydrostatic reduction was attempted in 49 patients, being permanently successful in 41 cases (selective reduction rate 41/49 = 83.7%; crude reduction rate 41/56 = 73.2%). The remaining eight patients underwent secondary surgery, with just two patients not requiring surgical bowel resection/intervention (corrected selective reduction rate 41/43 = 95.3%). The composite reduction rate was 87.2% (successful/feasible reductions, 41/47). Radiation-free sonography-guided hydrostatic reduction has a good success rate in children with ileocolic intussusception. It may be particularly valuable in centers that are already experienced with using sonography for the diagnosis.

Principles Guiding Vocabulary Learning through Extensive Reading

Science.gov (United States)

Nation, Paul

2015-01-01

Extensive reading is one of a range of activities that can be used in a language learning course. Ideally, the choice of activities to go into a course should be guided by principles which are well supported by research. Similarly, the way each of those activities is used should be guided by well-justified principles. In this article, we look at…

Gaze strategies during visually-guided versus memory-guided grasping.

Science.gov (United States)

Prime, Steven L; Marotta, Jonathan J

2013-03-01

Vision plays a crucial role in guiding motor actions. But sometimes we cannot use vision and must rely on our memory to guide action-e.g. remembering where we placed our eyeglasses on the bedside table when reaching for them with the lights off. Recent studies show subjects look towards the index finger grasp position during visually-guided precision grasping. But, where do people look during memory-guided grasping? Here, we explored the gaze behaviour of subjects as they grasped a centrally placed symmetrical block under open- and closed-loop conditions. In Experiment 1, subjects performed grasps in either a visually-guided task or memory-guided task. The results show that during visually-guided grasping, gaze was first directed towards the index finger's grasp point on the block, suggesting gaze targets future grasp points during the planning of the grasp. Gaze during memory-guided grasping was aimed closer to the blocks' centre of mass from block presentation to the completion of the grasp. In Experiment 2, subjects performed an 'immediate grasping' task in which vision of the block was removed immediately at the onset of the reach. Similar to the visually-guided results from Experiment 1, gaze was primarily directed towards the index finger location. These results support the 2-stream theory of vision in that motor planning with visual feedback at the onset of the movement is driven primarily by real-time visuomotor computations of the dorsal stream, whereas grasping remembered objects without visual feedback is driven primarily by the perceptual memory representations mediated by the ventral stream.

FAA Offers Free Guide on Elementary Aviation Education.

Science.gov (United States)

Journal of Aerospace Education, 1978

1978-01-01

Describes a teaching guide in aviation education for grades 2 through 6. The guide contains activities designed to enrich an existing science curriculum. An address for ordering the guide is included. (MA)

Body-mounted robotic instrument guide for image-guided cryotherapy of renal cancer

Science.gov (United States)

Hata, Nobuhiko; Song, Sang-Eun; Olubiyi, Olutayo; Arimitsu, Yasumichi; Fujimoto, Kosuke; Kato, Takahisa; Tuncali, Kemal; Tani, Soichiro; Tokuda, Junichi

2016-01-01

of 80 mm. The phantom test indicated that the accuracy of probe placement was significantly better with the robotic instrument guide (4.1 mm) than without the guide (6.3 mm, pcryotherapy of renal cancer and was done in fewer attempts and in less time than the free-hand approach. The accuracy of the placement of the cryotherapy probe was better using the robotic instrument guide than without the guide when no organ motion was present. The accuracy between the robotic and free-hand approach becomes comparable when organ motion was present. PMID:26843245

Stephen Hawking's Universe. Teacher's Guide.

Science.gov (United States)

Thompson, Malcolm H.; Rameau, Jonathan D.

This program guide is meant to help teachers assist their students in viewing the six-part public television series, "Stephen Hawking's Universe." The guide features program summaries that give background information and brief synopses of the programs; previewing activities that familiarize students with the subject; vocabulary that…

Retrieval activates related words more than presentation.

Science.gov (United States)

Hausman, Hannah; Rhodes, Matthew G

2018-03-23

Retrieving information enhances learning more than restudying. One explanation of this effect is based on the role of mediators (e.g., sand-castle can be mediated by beach). Retrieval is hypothesised to activate mediators more than restudying, but existing tests of this hypothesis have had mixed results [Carpenter, S. K. (2011). Semantic information activated during retrieval contributes to later retention: Support for the mediator effectiveness hypothesis of the testing effect. Journal of Experimental Psychology: Learning, Memory, and Cognition, 37(6), 1547-1552. doi: 10.1037/a0024140 ; Lehman, M., & Karpicke, J. D. (2016). Elaborative retrieval: Do semantic mediators improve memory? Journal of Experimental Psychology: Learning, Memory, and Cognition, 42(10), 1573-1591. doi: 10.1037/xlm0000267 ]. The present experiments explored an explanation of the conflicting results, testing whether mediator activation during a retrieval attempt depends on the accessibility of the target information. A target was considered less versus more accessible when fewer versus more cues were given during retrieval practice (Experiments 1 and 2), when the target had been studied once versus three times initially (Experiment 3), or when the target could not be recalled versus could be recalled during retrieval practice (Experiments 1-3). A mini meta-analysis of all three experiments revealed a small effect such that retrieval activated mediators more than presentation, but mediator activation was not reliably related to target accessibility. Thus, retrieval may enhance learning by activating mediators, in part, but these results suggest the role of other processes, too.

Global change and Canadians: A teacher's guide

International Nuclear Information System (INIS)

1993-01-01

A report called Global Change and Canadians has been produced by the Royal Society of Canada to answer basic questions being asked about global change issues. A teacher's guide is presented to help teachers make effective use of the report in developing programs with students concerning global change. A basic set of teaching and learning activities related to the major topics in the report is provided, curricular connections between global change topics and school programs are suggested, and some additional resources on global change are listed. The guide is divided into six chapters, each corresponding to the chapters of the global change report. Each chapter contains a summary of the major concepts from the report, some of the learning outcomes that occur when those concepts are addressed, a series of suggested activities or ideas, and a guide for assessing students' abilities relative to the concepts of the chapter. The topics of the chapters cover the nature of global change, the importance of global change to Canada, the causes of global change, the consequences of global change (including climate change and the greenhouse effect), the effects of global change on society, and Canadian responses to global change. 64 refs., 3 figs

Using a Combined Approach of Guided Inquiry & Direct Instruction to Explore How Physiology Affects Behavior

Science.gov (United States)

Machtinger, Erika T.

2014-01-01

Hands-on activities with live organisms allow students to actively explore scientific investigation. Here, I present activities that combine guided inquiry with direct instruction and relate how nutrition affects the physiology and behavior of the common housefly. These experiments encourage student involvement in the formulation of experimental…

Rationale and development of image-guided intensity-modulated radiotherapy post-prostatectomy: the present standard of care?

Directory of Open Access Journals (Sweden)

Murray JR

2015-11-01

Full Text Available Julia R Murray,1,2 Helen A McNair,2 David P Dearnaley1,2 1Academic Urology Unit, Institute of Cancer Research, London, 2Department of Radiotherapy, The Royal Marsden NHS Foundation Trust, Sutton, UK Abstract: The indications for post-prostatectomy radiotherapy have evolved over the last decade, although the optimal timing, dose, and target volume remain to be well defined. The target volume is susceptible to anatomical variations with its borders interfacing with the rectum and bladder. Image-guided intensity-modulated radiotherapy has become the gold standard for radical prostate radiotherapy. Here we review the current evidence for image-guided techniques with intensity-modulated radiotherapy to the prostate bed and describe current strategies to reduce or account for interfraction and intrafraction motion. Keywords: radiotherapy, prostate cancer, post-prostatectomy, image-guided radiation therapy

Anesthetic activity and bio-guided fractionation of the essential oil of Aloysia gratissima (Gillies & Hook.) Tronc. in silver catfish Rhamdia quelen.

Science.gov (United States)

Benovit, Simone C; Silva, Lenise L; Salbego, Joseânia; Loro, Vania L; Mallmann, Carlos A; Baldisserotto, Bernardo; Flores, Erico M M; Heinzmann, Berta M

2015-09-01

This work aimed to determine the efficacy of the essential oil of A. gratissima as anesthetic for silver catfish, and to perform the bio-guided fractionation of essential oil aiming to isolate compounds responsible for the noted effects. Fish were submitted to anesthesia bath with essential oil, its fractions and isolated compounds to determine time of anesthetic induction and recovery. Eugenol (50 mg L(-1)) was used as positive control. Essential oil of A. gratissima was effective as an anesthetic at concentrations of 300 to 900 mg L(-1). Fish presented involuntary muscle contractions during induction and recovery. The bio-guided fractionation of essential oil furnished E-(-)-pinocamphone, (-)-caryophyllene oxide, (-)-guaiol and (+)-spathulenol. E-(-)-pinocamphone caused the same side effects observed for essential oil. (-)-Caryophyllene oxide, (-)-guaiol and (+)-spathulenol showed only sedative effects at proportional concentrations to those of the constituents in essential oil. (+)-Spathulenol (51.2 mg L(-1)) promoted deep anesthesia without side effects. A higher concentration of (+)-spathulenol, and lower or absent amounts ofE-(-)-pinocamphone could contribute to increase the activity and safety of the essential oil of A. gratissima. (+)-Spathulenol showed potent sedative and anesthetic activities in silver catfish, and could be considered as a viable compound for the development of a new anesthetic.

SNAC: San Mateo Nutrition Activity Curriculum. "Swing Into Nutrition" (Staff In-Service Guide and Staff Workbook).

Science.gov (United States)

San Mateo City Elementary School District, CA.

This inservice training guide on nutrition activities for preschool and elementary school teachers consists of 14 lesson plans for two workshops and more than 20 related instructional handouts that can be copied for teachers. The first workshop for teachers provides a rationale for nutrition education ine elementary curriculum as well as…

Evaluation of cholinesterase inhibitory and antioxidant activities of wild and cultivated samples of sage (Salvia fruticosa) by activity-guided fractionation.

Science.gov (United States)

Senol, Fatma Sezer; Orhan, Ilkay Erdogan; Erdem, Sinem Aslan; Kartal, Murat; Sener, Bilge; Kan, Yüksel; Celep, Ferhat; Kahraman, Ahmet; Dogan, Musa

2011-11-01

In European folk medicine, Salvia species have traditionally been used to enhance memory. In our previous study of 55 Salvia taxa, we explored significant anticholinesterase activity of cultivated S. fruticosa. In this study, we compared the inhibitory activity of dichloromethane, ethyl acetate, and ethanol extracts of 3 wild-grown samples and 1 cultivated sample of S. fruticosa against acetylcholinesterase and butyrylcholinesterase enzymes (which are associated with pathogenesis of Alzheimer's disease) by using the spectrophotometric Ellman method. Antioxidant activities were assessed by determining 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity, iron-chelating capacity, and ferric-reducing antioxidant power. The dichloromethane extract of the cultivated sample was then subjected to fractionation by using open column chromatography and medium-pressure liquid chromatography to obtain the most active fraction by activity-guided fractionation. All fractions and subfractions were tested in the same manner, and inactive subfractions were discarded. The essential oil of the cultivated sample was analyzed by gas chromatography-mass spectrometry.

E3 Financing How-to Guide

Science.gov (United States)

The Financing How-to-Guide is intended to help manufacturers and their communities navigate financing and investment opportunities. While this guide provides an overview, there is no one-way to pay for E3 activities or attract investment.

South Carolina Guide for Small Business Management.

Science.gov (United States)

Vaughan, Ellen C.; Elliott, Ronald T.

This guide for small business management in South Carolina addresses the three domains of learning: psychomotor, cognitive, and affective. The guide contains suggestions for specific classroom activities for each domain. Each of the 11 units or tasks in the guide contains a competency statement followed by performance objectives, job-relevant…

Curriculum Guide for Fashion Merchandising (Fashion Salesperson).

Science.gov (United States)

Gregory, Margaret R.

This curriculum guide is designed to help teachers teach a course in fashion merchandising to high school students. The guide contains eight performance-based learning modules, each consisting of one to seven units. Each unit teaches a job-relevant task, and includes performance objectives, performance guides, resources, learning activities,…

Community Living Skills Guide: Art.

Science.gov (United States)

Sobol, Sheila; Kreps, Alice Roelofs

One of twenty course guides in the Community Living Skills Guide for the College for Living series, this document provides guidelines and workbook activities for the course, Art. The series of courses for developmentally disabled adults is intended to supplement residential programs and to aid in orienting institutionalized persons to eventual…

Activity-Guided Isolation of Antioxidant Compounds from Rhizophora apiculata

Directory of Open Access Journals (Sweden)

Hongbin Xiao

2012-09-01

Full Text Available Rhizophora apiculata (R. apiculata contains an abundance of biologically active compounds due its special salt-tolerant living surroundings. In this study, the total phenolic content and antioxidant activities of various extract and fractions of stem of R. apiculata were investigated. Results indicated that butanol fraction possesses the highest total phenolic content (181.84 mg/g GAE/g dry extract with strongest antioxidant abilities. Following in vitro antioxidant activity-guided phytochemical separation procedures, lyoniresinol-3α-O-β-arabinopyranoside (1, lyoniresinol-3α-O-β-rhamnoside (2, and afzelechin-3-O-L-rhamno-pyranoside (3 were separated from the butanol fraction. These compounds showed more noticeable antioxidant activity than a BHT standard in the DPPH, ABTS and hydroxyl radical scavenging assays. HPLC analysis results showed that among different plant parts, the highest content of 1–3 was located in the bark (0.068%, 0.066% and 0.011%, respectively. The results imply that the R. apiculata might be a potential source of natural antioxidants and 1–3 are antioxidant ingredients in R. apiculata.

Upstream petroleum industry flaring guide : review draft

International Nuclear Information System (INIS)

1999-03-01

The Alberta requirements and expectations for upstream petroleum flaring are presented. Flaring is associated with a wide range of energy activities including oil and gas well drilling and well completion operations. The guide incorporates the recommendations made to the Alberta Energy and Utilities Board (EUB) in June 1998 by the multi-stakeholder Clean Air Strategic Alliance (CASA) on associated or solution gas flaring. Additional requirements which address flaring issues not covered in the CASA report are also included in this guide. The Guide requires a 15 per cent reduction in solution gas flare volume by the end of year 2000 from the 1996 baseline, and a 25 per cent reduction by the end of 2001. The Guide prescribes new flare performance requirements for all flares, within three years for existing solution gas flares, five years for flares at other existing permanent facilities. It sets personal consultation and public notification requirements for new and existing solution gas batteries, and new sulphur recovery requirements for facilities not covered by existing EUB regulations. The Guide also addresses the question of conflict resolution to deal with flaring concerns, the release of flaring and venting data, the proposed reduction of flare limits, progress towards minimizing requirements for electricity generators using otherwise flared gas, annual reporting to the EUB, and management framework review in 2001

What's in Your Water? An Educator's Guide to Water Quality.

Science.gov (United States)

Constabile, Kerry, Comp.; Craig, Heidi, Comp.; O'Laughlin, Laura, Comp.; Reiss, Anne Bei, Comp.; Spencer, Liz, Comp.

This guide provides basic information on the Clean Water Act, watersheds, and testing for water quality, and presents four science lesson plans on water quality. Activities include: (1) "Introduction to Water Quality"; (2) "Chemical Water Quality Testing"; (3) "Biological Water Quality Testing"; and (4) "What Can We Do?" (YDS)

Safeguards Implementation Practices Guide on Facilitating IAEA Verification Activities

Energy Technology Data Exchange (ETDEWEB)

NONE

2014-12-15

The IAEA implements safeguards pursuant to agreements concluded with States. It is in the interests of both States and the IAEA to cooperate to facilitate the practical implementation of safeguards. Such cooperation is explicitly required under all types of safeguards agreement. Effective cooperation depends upon States and the IAEA sharing a common understanding of their respective rights and obligations. To address this, in 2012 the IAEA published Services Series 21, Guidance for States Implementing Comprehensive Safeguards Agreements and Additional Protocols, which aimed at enhancing understanding of the safeguards obligations of both States and the IAEA and at improving their cooperation in safeguards implementation. States may establish different processes and procedures at the national level, and set up different systems as required to meet their safeguards obligations. Indeed, a variety of approaches are to be expected, owing to such differences as the size and complexity of States’ nuclear programmes and their regulatory framework. The purpose of this Safeguards Implementation Practices (SIP) Guide is to share the experiences and good practices as well as the lessons learned by both States and the IAEA, acquired over the many decades of safeguards implementation. The information contained in the SIP Guides is provided for explanatory purposes and use of the Guides is not mandatory. The descriptions in the SIP Guides have no legal status and are not intended to add to, subtract from, amend or derogate from, in any way, the rights and obligations of the IAEA and the States set forth in The Structure and Content of Agreements between the Agency and States Required in Connection with the Treaty on the Non-Proliferation of Nuclear Weapons (issued as INFCIRC/153 (Corrected)) and Model Protocol Additional to the Agreement(s) between State(s) and the International Atomic Energy Agency for the Application of Safeguards (issued as INFCIRC/540 (Corrected)). This SIP

Safeguards Implementation Practices Guide on Facilitating IAEA Verification Activities

International Nuclear Information System (INIS)

2014-01-01

The IAEA implements safeguards pursuant to agreements concluded with States. It is in the interests of both States and the IAEA to cooperate to facilitate the practical implementation of safeguards. Such cooperation is explicitly required under all types of safeguards agreement. Effective cooperation depends upon States and the IAEA sharing a common understanding of their respective rights and obligations. To address this, in 2012 the IAEA published Services Series 21, Guidance for States Implementing Comprehensive Safeguards Agreements and Additional Protocols, which aimed at enhancing understanding of the safeguards obligations of both States and the IAEA and at improving their cooperation in safeguards implementation. States may establish different processes and procedures at the national level, and set up different systems as required to meet their safeguards obligations. Indeed, a variety of approaches are to be expected, owing to such differences as the size and complexity of States’ nuclear programmes and their regulatory framework. The purpose of this Safeguards Implementation Practices (SIP) Guide is to share the experiences and good practices as well as the lessons learned by both States and the IAEA, acquired over the many decades of safeguards implementation. The information contained in the SIP Guides is provided for explanatory purposes and use of the Guides is not mandatory. The descriptions in the SIP Guides have no legal status and are not intended to add to, subtract from, amend or derogate from, in any way, the rights and obligations of the IAEA and the States set forth in The Structure and Content of Agreements between the Agency and States Required in Connection with the Treaty on the Non-Proliferation of Nuclear Weapons (issued as INFCIRC/153 (Corrected)) and Model Protocol Additional to the Agreement(s) between State(s) and the International Atomic Energy Agency for the Application of Safeguards (issued as INFCIRC/540 (Corrected)). This SIP

MainXchange in the Classroom: The New Internet Stock Market Game. Teacher's Guide and Student Activities.

Science.gov (United States)

1998

This teaching guide/student activities booklet, for grades 6-9 and 7-11, outlines an Internet-based stock exchange simulation that allows students to learn about the stock market in a fun format. The simulation (the "MainXchange") described in the booklet offers students the opportunity to engage in "real-life" investing, while…

The Clubbers' Guide: A Treasure Trove of Science Activities/A Treasure Hunt through Time and Space

Science.gov (United States)

Howarth, Sue; Scott, Linda; Carter, Liz

2013-01-01

This issue of Clubbers' Guide contains an article written by Liz Carter, Senior Science Technician at the Warwick School, Redhill, Surrey (UK), describing some of the wide variety of science, technology, engineering and mathematics (STEM) based activities that her school puts on during an eight-day summer school in the holidays for prospective…

Antiprotozoal Activity of Buxus sempervirens and Activity-Guided Isolation of O-tigloylcyclovirobuxeine-B as the Main Constituent Active against Plasmodium falciparum

Directory of Open Access Journals (Sweden)

Julia B. Althaus

2014-05-01

Full Text Available Buxus sempervirens L. (European Box, Buxaceae has been used in ethnomedicine to treat malaria. In the course of our screening of plant extracts for antiprotozoal activity, a CH2Cl2 extract from leaves of B. sempervirens showed selective in vitro activity against Plasmodium falciparum (IC50 = 2.79 vs. 20.2 µg/mL for cytotoxicity against L6 rat cells. Separation of the extract by acid/base extraction into a basic and a neutral non-polar fraction led to a much more active and even more selective fraction with alkaloids while the fraction of non-polar neutral constituents was markedly less active than the crude extract. Thus, the activity of the crude extract could clearly be attributed to alkaloid constituents. Identification of the main triterpene-alkaloids and characterization of the complex pattern of this alkaloid fraction was performed by UHPLC/+ESI-QTOF-MS analyses. ESI-MS/MS target-guided larger scale preparative separation of the alkaloid fraction was performed by ‘spiral coil-countercurrent chromatography’. From the most active subfraction, the cycloartane alkaloid O-tigloylcyclovirobuxeine-B was isolated and evaluated for antiplasmodial activity which yielded an IC50 of 0.455 µg/mL (cytotoxicity against L6 rat cells: IC50 = 9.38 µg/mL. O-tigloylcyclovirobuxeine-B is thus most significantly responsible for the high potency of the crude extract.

Machine Accounting. An Instructor's Guide.

Science.gov (United States)

Gould, E. Noah, Ed.

Designed to prepare students to operate the types of accounting machines used in many medium-sized businesses, this instructor's guide presents a full-year high school course in machine accounting covering 120 hours of instruction. An introduction for the instructor suggests how to adapt the guide to present a 60-hour module which would be…

Specifications for human factors guiding documents

Energy Technology Data Exchange (ETDEWEB)

Rhodes, W; Szlapetis, I; MacGregor, C [Rhodes and Associates Inc., Toronto, ON (Canada)

1995-04-01

This report specifies the content, function and appearance of three proposed human factors guiding documents to be used by the Atomic Energy Control board and its licensees. These three guiding documents, to be developed at a later date, are: (a) Human Factors Process Guide; (b) Human Factors Activities Guide; and (c) Human Factors Design Integration Guide. The specifications were developed by examining the best documents as identified in a previous contract with the AECB (Review of Human Factors Guidelines and Methods by W. Rhodes, I. Szlapetis et al. 1992), and a brief literature review. The best features and content were selected from existing documents and used to develop specifications for the guiding documents. The developer of the actual guides would use these specifications to produce comprehensive and consolidated documents at a later date. (author). 128 ref., 7 figs.

Specifications for human factors guiding documents

International Nuclear Information System (INIS)

Rhodes, W.; Szlapetis, I.; MacGregor, C.

1995-04-01

This report specifies the content, function and appearance of three proposed human factors guiding documents to be used by the Atomic Energy Control board and its licensees. These three guiding documents, to be developed at a later date, are: (a) Human Factors Process Guide; (b) Human Factors Activities Guide; and (c) Human Factors Design Integration Guide. The specifications were developed by examining the best documents as identified in a previous contract with the AECB (Review of Human Factors Guidelines and Methods by W. Rhodes, I. Szlapetis et al. 1992), and a brief literature review. The best features and content were selected from existing documents and used to develop specifications for the guiding documents. The developer of the actual guides would use these specifications to produce comprehensive and consolidated documents at a later date. (author). 128 ref., 7 figs

Activation analysis in Europe: present and future perspectives

International Nuclear Information System (INIS)

De Corte, F.; Hoste, J.

1984-01-01

A survey is given of the present-day European contribution to activation analysis, covering neutron activation analysis (NAA), charged particle activation analysis (CPAA) and photon activation analysis (PAA). Attention is paid to the available irradiation facilities, in particular nuclear reactors, cyclotrons and Van de Graaff accelerators, and linear electron accelerators. Mention is made of progress in fundamental fields, but the attention is especially focussed on practical applications: environmental, geochemical/cosmochemical, biological/medical, and high-purity materials. Eventually, the role of activation analysis in research projects of the Commission of the European Communities (CEC) and in the Reference Materials program of the Community Bureau of Reference (BCR) is emphasized

Trypanocidal Activity of Smallanthus sonchifolius: Identification of Active Sesquiterpene Lactones by Bioassay-Guided Fractionation

Directory of Open Access Journals (Sweden)

F. M. Frank

2013-01-01

Full Text Available In order to find novel plant-derived biologically active compounds against Trypanosoma cruzi, we isolated, from the organic extract of Smallanthus sonchifolius, the sesquiterpene lactones enhydrin (1, uvedalin (2, and polymatin B (3 by bioassay-guided fractionation technique. These compounds showed a significant trypanocidal activity against the epimastigote forms of the parasite with IC50 values of 0.84 μM (1, 1.09 μM (2, and 4.90 μM (3. After a 24 h treatment with 10 μg/mL of enhydrin or uvedalin, parasites were not able to recover their replication rate. Compounds 1 and 2 showed IC50 values of 33.4 μM and 25.0 μM against T. cruzi trypomastigotes, while polymatin B was not active. When the three compounds were tested against the intracellular forms of T. cruzi, they were able to inhibit the amastigote replication with IC50 of 5.17 μM, 3.34 μM, and 9.02 μM for 1, 2, and 3, respectively. The cytotoxicity of the compounds was evaluated in Vero cells obtaining CC50 values of 46.5 μM (1, 46.8 μM (2, and 147.3 μM (3 and the selectivity index calculated. According to these results, enhydrin and uvedalin might have potentials as agents against Chagas disease and could serve as lead molecules to develop new drugs.

Learning to Fly: The Wright Brothers' Adventure. A Guide for Educators and Students with Activities in Aeronautics

Science.gov (United States)

Storm, R.; Benson, T.; Galica, C.; McCredie, P.

2003-01-01

This guide was produced by the NASA Glenn Research Center Office of Educational Programs in Cleveland, OH, and the NASA Aerospace Educational Coordinating Committee. It includes activity modules for students, including the history of the Wright Brothers and their family in Dayton, Ohio and flight experimentation in Kitty Hawk, North Carolina. Student activities such as building models of the Wright Brothers glider and writing press releases of the initial flight are included.

Percutaneous tracheostomy with the guide wire dilating forceps technique : presentation of 171 consecutive patients

NARCIS (Netherlands)

Fikkers, Bernard G; van Heerbeek, Niels; Krabbe, Paul F M; Marres, Henri A M; van den Hoogen, Frank J A

BACKGROUND: Evaluation of percutaneous tracheostomy (PT) with the guide wire dilating forceps (GWDF) technique. METHODS: Prospective study of perioperative complications, retrospective analysis of early and late complications in an ICU in a teaching university hospital. RESULTS: The success rate of

Percutaneous tracheostomy with the guide wire dilating forceps technique: presentation of 171 consecutive patients.

NARCIS (Netherlands)

Fikkers, B.G.; Heerbeek, N. van; Krabbe, P.F.M.; Marres, H.A.M.; Hoogen, F.J.A. van den

2002-01-01

BACKGROUND: Evaluation of percutaneous tracheostomy (PT) with the guide wire dilating forceps (GWDF) technique. METHODS: Prospective study of perioperative complications, retrospective analysis of early and late complications in an ICU in a teaching university hospital. RESULTS: The success rate of

PARK-IT! Elementary School Land Laboratories in Toledo City Parks. Curriculum Activity Guide, Grades K-1.

Science.gov (United States)

DuFour, Marilyn Berry; Courter, Linda Kothera; Garvin, Dennis M.

The project PARK-IT! represents a unique partnership between a public elementary school and a city park in which students and teachers utilize a small naturalized area of the park as a Land Laboratory, and in return become its stewards. The project also includes this curriculum activity guide which can assist teachers in using the Land Lab with…

PARK-IT! Elementary School Land Laboratories in Toledo City Parks. Curriculum Activity Guide, Grades 2-3.

Science.gov (United States)

DuFour, Marilyn Berry; Courter, Linda Kothera; Garvin, Dennis M.

The project PARK-IT! represents a unique partnership between a public elementary school and a city park in which students and teachers utilize a small naturalized area of the park as a Land Laboratory, and in return become its stewards. The project also includes this curriculum activity guide which can assist teachers in using the Land Lab with…

PARK-IT! Elementary School Land Laboratories in Toledo City Parks. Curriculum Activity Guide, Grades 4-6.

Science.gov (United States)

DuFour, Marilyn Berry; Courter, Linda Kothera; Garvin, Dennis M.

The project PARK-IT! represents a unique partnership between a public elementary school and a city park in which students and teachers utilize a small naturalized area of the park as a Land Laboratory, and in return become its stewards. The project also includes this curriculum activity guide which can assist teachers in using the Land Lab with…

Radon adsorption on present activated charcoals

International Nuclear Information System (INIS)

Kazankin, Yu.N.; Trofimov, A.M.; Mikhajlova, L.K.

1978-01-01

Radon adsorption from helium and air has been studied on modern activated carbons of SKT-1, SKT-2a, SKT-3, SKT-2b, SKT-6, PAU-1 within the temperature range from 100 to 80 deg. It has been shown that PAU-1 carbon has the highest activity with respect to radon in the temperature range studied. With decreasing temperature the adsorption coefficients increase sharply. It has been found that for the case of radon adsorption from helium the logarythm of the Henry coefficient linearly depends on the inverse value of absolute temperature. Adsorption of radon from air is inhibited and the above-cited relationship is deviated from linear. The results of calculating differential heats of radon and air adsorption as well as coefficients of radon and air separation on carbons are presented

Cognitive Control Network Contributions to Memory-Guided Visual Attention.

Science.gov (United States)

Rosen, Maya L; Stern, Chantal E; Michalka, Samantha W; Devaney, Kathryn J; Somers, David C

2016-05-01

Visual attentional capacity is severely limited, but humans excel in familiar visual contexts, in part because long-term memories guide efficient deployment of attention. To investigate the neural substrates that support memory-guided visual attention, we performed a set of functional MRI experiments that contrast long-term, memory-guided visuospatial attention with stimulus-guided visuospatial attention in a change detection task. Whereas the dorsal attention network was activated for both forms of attention, the cognitive control network(CCN) was preferentially activated during memory-guided attention. Three posterior nodes in the CCN, posterior precuneus, posterior callosal sulcus/mid-cingulate, and lateral intraparietal sulcus exhibited the greatest specificity for memory-guided attention. These 3 regions exhibit functional connectivity at rest, and we propose that they form a subnetwork within the broader CCN. Based on the task activation patterns, we conclude that the nodes of this subnetwork are preferentially recruited for long-term memory guidance of visuospatial attention. Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

Madison Public Schools. La Follette Careers Program. Tenth Grade Social Studies Guide.

Science.gov (United States)

Morrissey, Jim; Waity, Charles

A social studies course for a tenth grade career program is outlined in this curriculum and teaching guide. A calendar plots the time sequence for the nine units which cover prehistory to the present. The format of each unit is in three sections. The interrelated concepts, behavior goals, and teaching methods and learning activities are presented,…

Regulatory and law framework of agricultural methanization and composting activities. User's guide

International Nuclear Information System (INIS)

2008-08-01

After a presentation of the general context of organic waste management (its techniques, materials, legal and regulatory sources, i.e. European and French laws), this guide indicates the main regulatory and law aspects to those wishing to implement a project of methanization or composting of organic by-products in the agricultural sector. Several aspects are therefore discussed and presented in practical sheets. They concern the health and environment regulation, but not the professional risk prevention (explosion, fire, and so on). These aspects are the project setting up, input materials (animal by-products, organic materials coming from agricultural production or from out of it), waste collection and transport, process steps, organic product valorization, biogas valorization, solid and liquid release management

Cardiorespiratory fitness moderates the effect of an affect-guided physical activity prescription: a pilot randomized controlled trial.

Science.gov (United States)

Baldwin, Austin S; Kangas, Julie L; Denman, Deanna C; Smits, Jasper A J; Yamada, Tetsuhiro; Otto, Michael W

2016-11-01

Physical activity (PA) interventions have a clear role in promoting mental health. Current PA guidelines directed toward specific PA intensities may have negative effects on affective response to exercise, and affective response is an important determinant of PA adherence. In this randomized trial of 67 previously inactive adults, we compared the effects of a PA prescription emphasizing the maintenance of positive affect to one emphasizing a target heart rate, and tested the extent to which the effect of the affect-guided prescription on PA is moderated by cardiorespiratory fitness (CRF). We found the effect of an affect-guided prescription was significantly moderated by CRF. At one week, for participants with lower CRF (i.e. poor conditioning), the affect-guided prescription resulted in significantly greater change in PA minutes (M = 240.8) than the heart rate-guided prescription (M = 165.7), reflecting a moderate-sized effect (d = .55). For those with higher CRF (i.e. good conditioning), the means were in the opposite direction but not significantly different. At one month, the same pattern emerged but the interaction was not significant. We discuss the implications of these findings for the type of PA prescriptions offered to individuals in need.

Evaluating the Acceptability and Usability of EASEL: A Mobile Application that Supports Guided Reflection for Experiential Learning Activities

Directory of Open Access Journals (Sweden)

Jerry C Schnepp

2017-07-01

Full Text Available Aim/Purpose: To examine the early perceptions (acceptability and usability of EASEL (Education through Application-Supported Experiential Learning, a mobile platform that delivers reflection prompts and content before, during, and after an experiential learning activity. Background: Experiential learning is an active learning approach in which students learn by doing and by reflecting on the experience. This approach to teaching is often used in disciplines such as humanities, business, and medicine. Reflection before, during, and after an experience allows the student to analyze what they learn and why it is important, which is vital in helping them to understand the relevance of the experience. A just-in-time tool (EASEL was needed to facilitate this. Methodology: To inform the development of a mobile application that facilitates real-time guided reflection and to determine the relevant feature set, we conducted a needs analysis with both students and faculty members. Data collected during this stage of the evaluation helped guide the creation of a prototype. The user experience of the prototype and interface interactions were evaluated during the usability phase of the evaluation study. Contribution: Both the needs analysis and usability assessment provided justification for continued development of EASEL as well as insight that guides current development. Findings: The interaction design of EASEL is understandable and usable. Both students and teachers value an application that facilitates real-time guided reflection. Recommendations for Practitioners: The use of a system such as EASEL can leverage time and location-based services to support students in field experiences. This technology aligns with evidence that guided reflection provides opportunities for metacognition. Recommendation for Researchers: Iterative prototyping, testing, and refinement can lead to a deliberate and effective app development process. Impact on Society: The EASEL

Management of soils polluted by activities of a basic nuclear installations. Guide Nr 24, Release of the 2016/08/30

International Nuclear Information System (INIS)

2016-01-01

After having indicated the relevant regulatory texts and guides related to sanitation and dismantling, and having stated definitions of some important terms, this guide addresses the sanitation or soil management approach to be adopted as soon as a soil pollution requires it. This pollution can be radioactive or chemical, and the case of a pollution going out of the installation is also included. Legal responsibility is outlined. The guide aims then at detailing the articulation between the various concerned and relevant documents for the management of a radioactive or chemical pollution related to the activities of a basic nuclear installation (BNI), and at detailing ASN expectations in this respect. Thus, it recalls the adopted management approach and methodological tools: diagnosis, interpretation of environment condition, management plan. It describes the approach related to soil sanitation: diagnosis, document to be produced, field and additional investigations, implementation of the reference approach for a complete removal of pollution, actions to be undertaken when the application of the reference approach is impossible, end of sanitation works. The third part discusses the methodology of soil sanitation by excavation by distinguishing three defence lines, by discussing the management of excavated soils (management modalities, warehousing within the installation). Administrative procedures to be applied before, during and after sanitation works are then presented. Specific management approaches are indicated for a BNI being operated or being dismantled. Actions of information are also indicated. Finally, requirements in terms of quality assurance are evoked

Presentations for librarians a complete guide to creating effective, learner-centred presentations

CERN Document Server

Hilyer, Lee Andrew

2008-01-01

Recent research on learning from multimedia presentations has indicated that the current way many people prepare their slide presentations may actually hinder learning. Considering the ubiquity of the PowerPoint presentation in business and in education, presenters should be concerned whether or not their audience members are effectively receiving the information they wish to impart. This issue is of special import for librarians who teach, as they often must convey complex information in a very limited amount of time. Combining the best evidence on multimedia learning with real-world practica

Introductory Guide to European Corporate Law

DEFF Research Database (Denmark)

Fomcenco, Alex

Introductory Guide to European Corporate Law presents in an easily comprehensible and accessible way the main features and principles that govern European corporate law.......Introductory Guide to European Corporate Law presents in an easily comprehensible and accessible way the main features and principles that govern European corporate law....

Follow the guide!

CERN Multimedia

2003-01-01

For once it was the turn of the CERN guides to be shown around. A special tour had been organised for their annual outing on 24 June 2003, the aim of which was to go behind the scenes at research centres similar to CERN and discover the secrets of their public communications activities. The first stop was the European Synchrotron Radiation Facility (ESRF) in Grenoble, where the twenty or so CERN guides were welcomed by Dominique Cornujeols, head of communication at ESRF, who explained the Facility's history and purpose and how it operates before they were taken on a tour of the actual installations. CERN guides are welcomed to the ESRF (European Synchrotron Radiation Facility).The second visit of this trip to the Grenoble region was to the centre for science, technology and industry (CCSTI). "The people in charge at CCSTI showed us their day-to-day work in science and technology workshops", explains Stephan Petit, one of the guides. These workshops allow the public to discuss fundamental issues relating to a ...

Planetarium Educator's Workshop Guide. International Planetarium Society Special Report No. 10.

Science.gov (United States)

Friedman, Alan; And Others

Presented is a workshop guide for planetarium educators. Seven modules and four appendices focus on organizational patterns, learning theories, questioning strategies, activities for the planetarium, and incorporating all of the above into teaching. The four appendices include a list of the 1978 workshop participants, an annotated bibliography for…

Transportation and packaging resource guide

Energy Technology Data Exchange (ETDEWEB)

Arendt, J.W.; Gove, R.M.; Welch, M.J.

1994-12-01

The purpose of this resource guide is to provide a convenient reference document of information that may be useful to the U.S. Department of Energy (DOE) and DOE contractor personnel involved in packaging and transportation activities. An attempt has been made to present the terminology of DOE community usage as it currently exists. DOE`s mission is changing with emphasis on environmental cleanup. The terminology or nomenclature that has resulted from this expanded mission is included for the packaging and transportation user for reference purposes. Older terms still in use during the transition have been maintained. The Packaging and Transportation Resource Guide consists of four sections: Sect. 1, Introduction; Sect. 2, Abbreviations and Acronyms; Sect. 3, Definitions; and Sect. 4, References for packaging and transportation of hazardous materials and related activities, and Appendices A and B. Information has been collected from DOE Orders and DOE documents; U.S Department of Transportation (DOT), U.S. Environmental Protection Agency (EPA), and U.S. Nuclear Regulatory Commission (NRC) regulations; and International Atomic Energy Agency (IAEA) standards and other international documents. The definitions included in this guide may not always be a regulatory definition but are the more common DOE usage. In addition, the definitions vary among regulatory agencies. It is, therefore, suggested that if a definition is to be used in a regulatory or a legal compliance issue, the definition should be verified with the appropriate regulation. To assist in locating definitions in the regulations, a listing of all definition sections in the regulations are included in Appendix B. In many instances, the appropriate regulatory reference is indicated in the right-hand margin.

Transportation and packaging resource guide

International Nuclear Information System (INIS)

Arendt, J.W.; Gove, R.M.; Welch, M.J.

1994-12-01

The purpose of this resource guide is to provide a convenient reference document of information that may be useful to the U.S. Department of Energy (DOE) and DOE contractor personnel involved in packaging and transportation activities. An attempt has been made to present the terminology of DOE community usage as it currently exists. DOE's mission is changing with emphasis on environmental cleanup. The terminology or nomenclature that has resulted from this expanded mission is included for the packaging and transportation user for reference purposes. Older terms still in use during the transition have been maintained. The Packaging and Transportation Resource Guide consists of four sections: Sect. 1, Introduction; Sect. 2, Abbreviations and Acronyms; Sect. 3, Definitions; and Sect. 4, References for packaging and transportation of hazardous materials and related activities, and Appendices A and B. Information has been collected from DOE Orders and DOE documents; U.S Department of Transportation (DOT), U.S. Environmental Protection Agency (EPA), and U.S. Nuclear Regulatory Commission (NRC) regulations; and International Atomic Energy Agency (IAEA) standards and other international documents. The definitions included in this guide may not always be a regulatory definition but are the more common DOE usage. In addition, the definitions vary among regulatory agencies. It is, therefore, suggested that if a definition is to be used in a regulatory or a legal compliance issue, the definition should be verified with the appropriate regulation. To assist in locating definitions in the regulations, a listing of all definition sections in the regulations are included in Appendix B. In many instances, the appropriate regulatory reference is indicated in the right-hand margin

Parents and Schools: Success through Partnership. A Presentation Guide for School Administration & Teachers = Arriba los padres y las escuelas: una asociacion critica. Guia para padres hispanos.

Science.gov (United States)

Baron, Augustine, Jr.; Vasquez, Melba J. T.

These two documents pertain to the "Parents and Schools: Success through Partnership" program. The presentation guide for school administrators and Teachers" is intended to help school personnel present the program and its associated video, which addresses common culturally-based causes of misunderstandings between Hispanic American parents and…

RADTRAN 4: User guide

International Nuclear Information System (INIS)

Neuhauser, K.S.; Kanipe, F.L.

1992-01-01

RADTRAN 4 is used to evaluate radiological consequences of incident-free transportation, as well as the radiological risks from vehicular accidents occurring during transportation. This User Guide is Volume 3 in a series of four volume of the documentation of the RADTRAN 4 computer code for transportation risk analysis. The other three volumes are Volume 1, the Executive Summary; Volume 2, the Technical Manual; and Volume 4, the Programmer's Manual. The theoretical and calculational basis for the operations performed by RADTRAN 4 are discussed in Volume 2. Throughout this User Guide the reader will be referred to Volume 2 for detailed discussions of certain RADTRAN features. This User Guide supersedes the document ''RADTRAN III'' by Madsen et al. (1983). This RADTRAN 4 User Guide specifies and describes the required data, control inputs, input sequences, user options, program limitations, and other activities necessary for execution of the RADTRAN 4 computer code

Collegiate Drug Management Guide.

Science.gov (United States)

Janosik, Steven M.; Anderson, David S.

A checklist to help colleges and universities reevaluate their policies and procedures regarding drug use among college students is presented. It is designed to supplement the "Collegiate Alcohol Risk Assessment Guide." In this guide drugs other than alcohol are of concern, although alcohol is viewed by many as the "drug of choice" among college…

Therapeutic outcome of CT-guided radiofrequency ablation in patients with osteoid osteoma

Energy Technology Data Exchange (ETDEWEB)

Lassalle, Louis; Campagna, R.; Corcos, G.; Feydy, A. [Hopital Cochin-APHP Paris Universite Paris Descartes, Service de Radiologie Osteo-Articulaire, Paris (France); Babinet, A. [Hopital Cochin-APHP Paris Universite Paris Descartes, Service de Chirurgie Orthopedique, Paris (France); Larousserie, F. [Hopital Cochin-APHP Paris Universite Paris Descartes, Service d' Anatomo-Pathologie, Paris (France); Stephanazzi, J. [Hopital Cochin-APHP Paris Universite Paris Descartes, Service d' Anesthesie, Paris (France)

2017-07-15

To assess the long-term outcome of computed tomography-guided radiofrequency ablation (CT-guided RFA) in patients with suspected osteoid osteoma (OO). Single-center retrospective study. Patients with clinical suspicion and imaging diagnosis of osteoid osteoma were treated by CT-guided RFA using the same device with either a 7- or 10-mm active tip electrode. Specific precautions were applied in case of articular or spinal OO. Patients were contacted by phone to evaluate the long-term outcome in terms of pain, ability to perform daily activities (including sports), and long-term complications. Success was defined as the absence of residual pain and ability to perform daily activities normally. From 2008 to 2015, 126 patients were treated by CT-guided RFA for OO in our institution. Mean patient age was 26.1 years (SD = 11, range 1-53); mean delay to diagnosis was 16.9 months (SD = 15.2, range 1-120). Among patients who answered the follow-up call (n = 88), the overall success rate was 94.3%: 79/88 (89.8%) had primary success of the procedure, and 4/88 (4.5%) had a secondary success (repeat-RFA after pain recurrence). Mean follow-up time was 34.6 months (SD = 24.7, range 3-90). Few complications occurred: two mild reversible peripheral nerve injuries, one brachial plexus neuropathy, one broken electrode tip fragment, and one muscular hematoma. Osteoid osteoma can be effectively and safely treated by CT-guided RFA using the presented ablation protocol. Beneficial effects of the treatment persist at long-term follow-up. (orig.)

Therapeutic outcome of CT-guided radiofrequency ablation in patients with osteoid osteoma

International Nuclear Information System (INIS)

Lassalle, Louis; Campagna, R.; Corcos, G.; Feydy, A.; Babinet, A.; Larousserie, F.; Stephanazzi, J.

2017-01-01

To assess the long-term outcome of computed tomography-guided radiofrequency ablation (CT-guided RFA) in patients with suspected osteoid osteoma (OO). Single-center retrospective study. Patients with clinical suspicion and imaging diagnosis of osteoid osteoma were treated by CT-guided RFA using the same device with either a 7- or 10-mm active tip electrode. Specific precautions were applied in case of articular or spinal OO. Patients were contacted by phone to evaluate the long-term outcome in terms of pain, ability to perform daily activities (including sports), and long-term complications. Success was defined as the absence of residual pain and ability to perform daily activities normally. From 2008 to 2015, 126 patients were treated by CT-guided RFA for OO in our institution. Mean patient age was 26.1 years (SD = 11, range 1-53); mean delay to diagnosis was 16.9 months (SD = 15.2, range 1-120). Among patients who answered the follow-up call (n = 88), the overall success rate was 94.3%: 79/88 (89.8%) had primary success of the procedure, and 4/88 (4.5%) had a secondary success (repeat-RFA after pain recurrence). Mean follow-up time was 34.6 months (SD = 24.7, range 3-90). Few complications occurred: two mild reversible peripheral nerve injuries, one brachial plexus neuropathy, one broken electrode tip fragment, and one muscular hematoma. Osteoid osteoma can be effectively and safely treated by CT-guided RFA using the presented ablation protocol. Beneficial effects of the treatment persist at long-term follow-up. (orig.)

Control of activities at the neighbourhood of basic nuclear installations. Guide Nr 15, Release of the 2016/03/24

International Nuclear Information System (INIS)

2016-01-01

After having indicated the relevant regulatory texts, and described the context (the taking of nuclear activities into account in various town and land planning documents), this guide defines the ASN national doctrine for the control of activities about basic nuclear installations (BNI) and at presenting tools aiming at limiting the presence and growth of populations exposed to nuclear risks. It recalls and discusses the four main pillars of the management of risks posed by BNIs: risk reduction at the origin (on charge of the operator), implementation of emergency and rescue plans, preventive information of population and local communities, and control of activities in areas exposed to the risks. It states the principles adopted by the ASN regarding the control of activities about BNIs. This doctrine is based on three principles: to preserve the rescue plan operability, to favour a local development beyond an area of risk with fast kinetics, and to enable a controlled development which responds to the needs of the resident population. Then, the issue of land use conditions is addressed and discussed: objectives to be reached, discussion of vulnerability levels depending on activities, management of new projects by using various tools (servitude of public interest, town planning documents and code)

A linear maglev guide for machine tools

Energy Technology Data Exchange (ETDEWEB)

Tieste, K D [Inst. of Mechanics, Univ. of Hannover (Germany); Popp, K [Inst. of Mechanics, Univ. of Hannover (Germany)

1996-12-31

Machine tools require linear guides with high slide velocity and very high position accuracy. The three tasks of a linear guide - supporting, guiding and driving - shall be realised by means of active magnetic bearings (AMB). The resulting linear magnetically levitated (maglev) guide has to accomplish the following characteristics: High stiffness, good damping and low noise as well as low heat production. First research on a one degree-of-freedom (DOF) support magnet unit aimed at the development of components and efficient control strategies for the linear maglev guide. The actual research is directed to realise a five DOF linear maglev guide for machine tools without drive to answer the question whether the maglev principle can be used for a linear axis in a machine tool. (orig.)

TRAC User's Guide

International Nuclear Information System (INIS)

Boyack, B.E.; Stumpf, H.; Lime, J.F.

1985-11-01

This guide has been prepared to assist users in applying the Transient Reactor Analysis Code (TRAC). TRAC is an advanced best-estimate systems code for analyzing transients in thermal-hydraulic systems. The code is very general. Because it is general, efforts to model specific nuclear power plants or experimental facilities often present a challenge to the TRAC user. This guide has been written to assist first-time or intermediate users. It is specifically written for the TRAC version designated TRAC-PF1/MOD1. The TRAC User's Guide should be considered a companion document to the TRAC Code Manual; the user will need both documents to use TRAC effectively. 18 refs., 45 figs., 19 tabs

Teacher's Guide for Balloons and Gases.

Science.gov (United States)

Griffith, Joe H.; And Others

This guide was developed to provide children with an opportunity to prepare and collect several common gases and to discover and work with some of their properties. The guide is divided into five major sections: (1) introduction, (2) materials, (3) activities, (4) balloons aloft, and (5) an appendix. The introduction provides information…

Teaching Guide for Building Maintenance Occupations.

Science.gov (United States)

Kempton, Robert F.

This teaching guide for building maintenance is one of a series of five performance- and employer-based secondary level vocational education guides. Part 1 provides tools, resources, and a process to be used at the local level to develop a training curriculum and supporting instructional activities. It includes a comprehensive overview of the…

MRI-guided vacuum-assisted breast biopsy: comparison with stereotactically guided and ultrasound-guided techniques

Energy Technology Data Exchange (ETDEWEB)

Imschweiler, Thomas; Freiwald, Bianka; Kubik-Huch, Rahel A. [Kantonspital Baden AG, Institute for Radiology, Baden (Switzerland); Haueisen, Harald [Kantonspital Aarau AG, Institute for Radiology, Aarau (Switzerland); Kampmann, Gert [Clinica Sant' Anna, Lugano, Sorengo (Switzerland); Rageth, Luzi [Adjumed Services AG, Zurich (Switzerland); Seifert, Burkhardt [Institute for Social and Preventive Medicine, University of Zurich, Division of Biostatistics, Zuerich (Switzerland); Rageth, Christoph [Breast Centre, Zurich (Switzerland)

2014-01-15

To analyse the development of MRI-guided vacuum-assisted biopsy (VAB) in Switzerland and to compare the procedure with stereotactically guided and ultrasound-guided VAB. We performed a retrospective analysis of VABs between 2009 and 2011. A total of 9,113 VABs were performed. Of these, 557 were MRI guided. MRI-guided VAB showed the highest growth rate (97 %) of all three procedures. The technical success rates for MRI-guided, stereotactically guided and ultrasound-guided VAB were 98.4 % (548/557), 99.1 % (5,904/5,960) and 99.6 % (2,585/2,596), respectively. There were no significant differences (P = 0.12) between the MRI-guided and the stereotactically guided procedures. The technical success rate for ultrasound-guided VAB was significantly higher than that for MRI-guided VAB (P < 0.001). There were no complications using MRI-guided VAB requiring open surgery. The malignancy diagnosis rate for MRI-guided VAB was similar to that for stereotactically guided VAB (P = 0.35). MRI-guided VAB is a safe and accurate procedure that provides insight into clinical breast findings. (orig.)

Control system design guide

Energy Technology Data Exchange (ETDEWEB)

Sellers, David; Friedman, Hannah; Haasl, Tudi; Bourassa, Norman; Piette, Mary Ann

2003-05-01

The ''Control System Design Guide'' (Design Guide) provides methods and recommendations for the control system design process and control point selection and installation. Control systems are often the most problematic system in a building. A good design process that takes into account maintenance, operation, and commissioning can lead to a smoothly operating and efficient building. To this end, the Design Guide provides a toolbox of templates for improving control system design and specification. HVAC designers are the primary audience for the Design Guide. The control design process it presents will help produce well-designed control systems that achieve efficient and robust operation. The spreadsheet examples for control valve schedules, damper schedules, and points lists can streamline the use of the control system design concepts set forth in the Design Guide by providing convenient starting points from which designers can build. Although each reader brings their own unique questions to the text, the Design Guide contains information that designers, commissioning providers, operators, and owners will find useful.

Determinants of Dutch general practitioners’ nutrition and physical activity guidance practices

NARCIS (Netherlands)

Hiddink, G.J.; Woerkum, van C.M.J.; Dillen, van S.M.E.

2013-01-01

Objective General practitioners (GP) are uniquely placed to guide their patients on nutrition and physical activity. The aims of the present study were to assess: (i) the extent to which GP guide on nutrition and physical activity; (ii) the determinants that cause GP to give guidance on nutrition

Optical Design of COATLI: A Diffraction-Limited Visible Imager with Fast Guiding and Active Optics Correction

Science.gov (United States)

Fuentes-Fernández, J.; Cuevas, S.; Watson, A. M.

2018-04-01

We present the optical design of COATLI, a two channel visible imager for a comercial 50 cm robotic telescope. COATLI will deliver diffraction-limited images (approximately 0.3 arcsec FWHM) in the riz bands, inside a 4.2 arcmin field, and seeing limited images (approximately 0.6 arcsec FWHM) in the B and g bands, inside a 5 arcmin field, by means of a tip-tilt mirror for fast guiding, and a deformable mirror for active optics, both located on two optically transferred pupil planes. The optical design is based on two collimator-camera systems plus a pupil transfer relay, using achromatic doublets of CaF2 and S-FTM16 and one triplet of N-BK7 and CaF2. We discuss the effciency, tolerancing, thermal behavior and ghosts. COATLI will be installed at the Observatorio Astronómico Nacional in Sierra San Pedro Mártir, Baja California, Mexico, in 2018.

Power point 2002 for successful presentation

International Nuclear Information System (INIS)

Moon, Insoo

2002-01-01

This book mentions power point 2002 for successful presentation, which deals with power point and presentation, all guide, the latest gear, for presentation, basic of power point 2002 such as slide, text compile, insertion of picture, figure and application of office guide, setting up new year plan using text like insertion text with various methods, compile effective text, and 200% application of tab, and addiction of pretty shape of characters, finishing of conversion of chinese character, and elimination of typographical error with spell checker.

Pond and Stream Safari: A Guide to the Ecology of Aquatic Invertebrates.

Science.gov (United States)

Edelstein, Karen

This packet includes a leader's guide, a quick reference guide to aquatic invertebrates, a checklist of common aquatic invertebrates, and activity sheets. The leader's guide includes four sections on background information and seven activities. Background sections include: Understanding Aquatic Insects; Growing Up: Aquatic Insect Forms; Adapting…

Using human brain activity to guide machine learning.

Science.gov (United States)

Fong, Ruth C; Scheirer, Walter J; Cox, David D

2018-03-29

Machine learning is a field of computer science that builds algorithms that learn. In many cases, machine learning algorithms are used to recreate a human ability like adding a caption to a photo, driving a car, or playing a game. While the human brain has long served as a source of inspiration for machine learning, little effort has been made to directly use data collected from working brains as a guide for machine learning algorithms. Here we demonstrate a new paradigm of "neurally-weighted" machine learning, which takes fMRI measurements of human brain activity from subjects viewing images, and infuses these data into the training process of an object recognition learning algorithm to make it more consistent with the human brain. After training, these neurally-weighted classifiers are able to classify images without requiring any additional neural data. We show that our neural-weighting approach can lead to large performance gains when used with traditional machine vision features, as well as to significant improvements with already high-performing convolutional neural network features. The effectiveness of this approach points to a path forward for a new class of hybrid machine learning algorithms which take both inspiration and direct constraints from neuronal data.

3D Guided Wave Motion Analysis on Laminated Composites

Science.gov (United States)

Tian, Zhenhua; Leckey, Cara; Yu, Lingyu

2013-01-01

Ultrasonic guided waves have proved useful for structural health monitoring (SHM) and nondestructive evaluation (NDE) due to their ability to propagate long distances with less energy loss compared to bulk waves and due to their sensitivity to small defects in the structure. Analysis of actively transmitted ultrasonic signals has long been used to detect and assess damage. However, there remain many challenging tasks for guided wave based SHM due to the complexity involved with propagating guided waves, especially in the case of composite materials. The multimodal nature of the ultrasonic guided waves complicates the related damage analysis. This paper presents results from parallel 3D elastodynamic finite integration technique (EFIT) simulations used to acquire 3D wave motion in the subject laminated carbon fiber reinforced polymer composites. The acquired 3D wave motion is then analyzed by frequency-wavenumber analysis to study the wave propagation and interaction in the composite laminate. The frequency-wavenumber analysis enables the study of individual modes and visualization of mode conversion. Delamination damage has been incorporated into the EFIT model to generate "damaged" data. The potential for damage detection in laminated composites is discussed in the end.

Presentation and exhibition activities for promoting theexportof transport services

Directory of Open Access Journals (Sweden)

Darya Vladimirovna Nesterova

2012-03-01

Full Text Available Development of presentation and exhibition activities is considered as an important factor in providing new competitive advantages at the strategic markets for exporting of transportation services. A specific role for exhibition activities as a factor to overcome market failures arose from imperfect information and incomplete markets is displayed. Exhibitions are considered as a true reflection of most market parameters, as a means to get correct information concerning market capacity and its borders, as an instrument to access to new markets. At the firm level presentation and branding activities should be considered as a modern technology (especially it concerns Russian companies which provide to hold up already existed markets and to conquer new ones. Presentation and branding activities are an effective technology to promote company trade-mark, competitive advantages for market demand increasing. Comparative analysis of the main exhibitions on transport and logistics issues is fulfilled on the data basecollected by authors. Data observes geographical distribution of transport exhibition and exhibition facilities development at several regions for the last years. The analyses allow to revealing a geographical structure of the exhibitions and its distribution by type of transport. The most promising and economically favorable exhibition areas for the promotion of Russian transport services are shown.

School Chemistry Laboratory Safety Guide

Science.gov (United States)

Brundage, Patricia; Palassis, John

2006-01-01

The guide presents information about ordering, using, storing, and maintaining chemicals in the high school laboratory. The guide also provides information about chemical waste, safety and emergency equipment, assessing chemical hazards, common safety symbols and signs, and fundamental resources relating to chemical safety, such as Material…

In Vivo Tooth-Supported Implant Surgical Guides Fabricated With Desktop Stereolithographic Printers: Fully Guided Surgery Is More Accurate Than Partially Guided Surgery.

Science.gov (United States)

Bencharit, Sompop; Staffen, Adam; Yeung, Matthew; Whitley, Daniel; Laskin, Daniel M; Deeb, George R

2018-02-21

Desktop stereolithographic printers combined with intraoral scanning and implant planning software promise precise and cost-effective guided implant surgery. The purpose of the present study was to determine the overall range of accuracy of tooth-supported guided implant surgery using desktop printed stereolithographic guides. A cross-sectional study comparing fully and partially guided implant surgery was conducted. Preoperative cone beam computed tomography (CBCT) and intraoral scans were used to plan the implant sites. Surgical guides were then fabricated using a desktop stereolithographic 3-dimensional printer. Postoperative CBCT was used to evaluate the accuracy of placement. Deviations from the planned positions were used as the primary outcome variables. The planning software used, implant systems, and anterior/posterior positions were the secondary outcome variables. The differences between the planned and actual implant positions in the mesial, distal, buccal, and lingual dimensions and buccolingual angulations were determined, and the accuracy was compared statistically using the 1-tail F-test (P = .01), box plots, and 95% confidence intervals for the mean. Sixteen partially edentulous patients requiring placement of 31 implants were included in the present study. The implant deviations from the planned positions for mesial, distal, buccal, and lingual dimensions and buccolingual angulations with the fully guided protocol (n = 20) were 0.17 ± 0.78 mm, 0.44 ± 0.78 mm, 0.23 ± 1.08 mm, -0.22 ± 1.44 mm, and -0.32° ± 2.36°, respectively. The corresponding implant deviations for the partially guided protocol (n = 11) were 0.33 ± 1.38 mm, -0.03 ± 1.59 mm, 0.62 ± 1.15 mm, -0.27 ± 1.61 mm, and 0.59° ± 6.83°. The difference between the variances for fully and partially guided surgery for the distal and angulation dimensions was statistically significant (P = .006 and P guided implant surgery is more accurate than

The influence of guides on alcohol consumption among young tourists at a nightlife resort

DEFF Research Database (Denmark)

Tutenges, Sébastien; Jæger, Mads Meier; Hesse, Morten

2012-01-01

Objective: The aim of this study was to assess how participation in party activities with guides affects alcohol consumption among young tourists at an international nightlife resort. Methods: Prospective survey of 112 Danish tourists in Sunny Beach, Bulgaria, who were asked about their drinking...... and activities with guides on three separate nights out. Results: Participation in party activities with guides such as drinking games and Pub Crawls, were associated with heavily increased drinking compared with nights out without guides, but not in a dose-response type relationship. Conclusion: Participating...... in party activities with guides increases drinking among young tourists who are already drinking large amounts of alcohol during their vacation. Further studies are needed to measure, describe and change the role played by guides at nightlife resorts....

SYMPAL: utilities guide

International Nuclear Information System (INIS)

Simpson, J.A.; Sublet, J.-Ch.

1997-02-01

The processing code SYMPAL is used to perform the data treatment for creating a new version of the European Activation File (EAF). The entire process is handled by different modules of the code in a sequential and orderly manner. The modular code system accesses, translates and processes cross section data from a wide variety of libraries and calculations with nuclear model codes. Two major data bases are accessed and merged so as to create a new library version. The Master Data File (MDF) contains the original cross section data extracted, unmodified but reformatted, from numerous sources. The Master Parameter File (MPF) contains a compilation of all physical information necessary to renormalise, split and internally validate any particular type of cross section. The combination of these two files generates a new activation library in pointwise and various groupwise formats. The SYMPAL utilities guide describes a set of programs developed to handle certain aspects of the procedure done outside of the main processing tasks. These include counting, translating, selecting and plotting data streams. Special printing and plotting procedures have been written to handle the large amounts of information present in activation libraries. (author)

The Guided Autobiography Method: A Learning Experience

Science.gov (United States)

Thornton, James E.

2008-01-01

This article discusses the proposition that learning is an unexplored feature of the guided autobiography method and its developmental exchange. Learning, conceptualized and explored as the embedded and embodied processes, is essential in narrative activities of the guided autobiography method leading to psychosocial development and growth in…

Bio-guided fractionation of methanol extract of Ziziphus mauritiana Lam. (bark and effect of the most active fraction on cancer cell lines

Directory of Open Access Journals (Sweden)

Richard Simo Tagne

2015-04-01

Full Text Available Objective: To investigate the anticancer and antioxidant potential of methanol bark extract of Ziziphus mauritiana (Z. mauritiana, which is used by traditional healers to cure some cases of cancer in Cameroon. Methods: The methanol crude extract of Z. mauritiana has the antiproliferative activity on four cancer cell lines and its antioxidant activity. The extract was partitioned in five different solvents, and each fraction was tested. The effect of the most antiproliferative fraction on cell cycle was determined. Bio-guided fractionation was performed on the fraction with the highest antiproliferative and the highest antioxidant activities. Results: Z. mauritiana methanol extract was active on all tested cells, and showed promising antioxidant activity. All fractions except hexane fraction were active with the dichloromethane fraction being the most active and showed S and G2-M phase arrest (P<0.01 on cell cycle progression of NCI-H460 and MCF-7, respectively. Bio-guided fractionation of the dichloromethane fraction led to lupeol and betulinic acid. The greatest antioxidant activity was recorded with ethyl acetate fraction and its fractionation led to catechin and epigallocatechin. Conclusions: Overall, this study showed that Z. mauritiana barks has benefits as a chemoprevention agent cancer.

Safety guides development process in Spain

International Nuclear Information System (INIS)

Butragueno, J.L.; Perello, M.

1979-01-01

Safety guides have become a major factor in the licensing process of nuclear power plants and related nuclear facilities of the fuel cycle. As far as the experience corroborates better and better engineering methodologies and procedures, the results of these are settled down in form of standards, guides, and similar issues. This paper presents the actual Spanish experience in nuclear standards and safety guides development. The process to develop a standard or safety guide is shown. Up to date list of issued and on development nuclear safety guides is included and comments on the future role of nuclear standards in the licensing process are made. (author)

Guide-Plane Retention in Designing Removable Partial Dentures.

Science.gov (United States)

Mothopi-Peri, Matshediso; Owen, C Peter

To compare the influence of abutment teeth guide planes and guiding surfaces on retention of a removable partial denture (RPD). Extracted teeth embedded into a maxillary cast in the first premolar and second molar positions simulated two bounded saddles. Acrylic resin RPDs were made with no guide planes, then with guide planes, then with guiding surfaces added to directly contact the guide planes. The maximum loads on removal from the cast were recorded. There was a significant increase in retention force of 1.6 times when only guide planes were present and of 10.2 times when guiding surfaces intimately contacted the guide planes. The retention of acrylic resin RPDs can be substantially increased by making their guiding surfaces intimately contact the guide planes of the teeth.

Therapeutic outcome of CT-guided radiofrequency ablation in patients with osteoid osteoma.

Science.gov (United States)

Lassalle, Louis; Campagna, R; Corcos, G; Babinet, A; Larousserie, F; Stephanazzi, J; Feydy, A

2017-07-01

To assess the long-term outcome of computed tomography-guided radiofrequency ablation (CT-guided RFA) in patients with suspected osteoid osteoma (OO). Single-center retrospective study. Patients with clinical suspicion and imaging diagnosis of osteoid osteoma were treated by CT-guided RFA using the same device with either a 7- or 10-mm active tip electrode. Specific precautions were applied in case of articular or spinal OO. Patients were contacted by phone to evaluate the long-term outcome in terms of pain, ability to perform daily activities (including sports), and long-term complications. Success was defined as the absence of residual pain and ability to perform daily activities normally. From 2008 to 2015, 126 patients were treated by CT-guided RFA for OO in our institution. Mean patient age was 26.1 years (SD = 11, range 1-53); mean delay to diagnosis was 16.9 months (SD = 15.2, range 1-120). Among patients who answered the follow-up call (n = 88), the overall success rate was 94.3%: 79/88 (89.8%) had primary success of the procedure, and 4/88 (4.5%) had a secondary success (repeat-RFA after pain recurrence). Mean follow-up time was 34.6 months (SD = 24.7, range 3-90). Few complications occurred: two mild reversible peripheral nerve injuries, one brachial plexus neuropathy, one broken electrode tip fragment, and one muscular hematoma. Osteoid osteoma can be effectively and safely treated by CT-guided RFA using the presented ablation protocol. Beneficial effects of the treatment persist at long-term follow-up.

GreyGuide Forum and Repository

OpenAIRE

Biagioni, Stefania; Farace, Dominic

2014-01-01

We present the GreyGuide: an online forum and repository of good practice in the field of grey literature. The launch of the GreyGuide Repository took place in December 2013 at the Fifteenth International Conference on Grey Literature. Since then, the acquisition of both proposed and published good practices are underway. The GreyGuide as an online forum is currently in a developmental stage and is influenced by the changes that have taken place in GreyNet's new infrastructure commencing in J...

Recent Ultrasonic Guided Wave Inspection Development Efforts

International Nuclear Information System (INIS)

Rose, Joseph L.; Tittmann, Bernhard R.

2001-01-01

The recognition of such natural wave guides as plates, rods, hollow cylinders, multi-layer structures or simply an interface between two materials combined with an increased understanding of the physics and wave mechanics of guided wave propagation has led to a significant increase in the number of guided wave inspection applications being developed each year. Of primary attention Is the ability to inspect partially hidden structures, hard to access areas, and treated or insulated structures. An introduction to some physical consideration of guided waves followed by some sample problem descriptions in pipe, ice detection, fouling detection in the foods industry, aircraft, tar coated structures and acoustic microscopy is presented in this paper. A sample problem in Boundary Element Modeling is also presented to illustrate the move in guided wave analysis beyond detection and location analysis to quantification

Water Pollution, Environmental Science Curriculum Guide Supplement.

Science.gov (United States)

McKenna, Harold J.

This curriculum guide is a 40-day unit plan on water pollution developed, in part, from the National Science Foundation Environmental Science Institutes' Ninth Grade Environmental Science Curriculum Guide. This unit contains teacher lesson plans, suggested teacher and student modules, case studies, and activities to be developed by teachers…

Advanced Energy Retrofit Guide Office Buildings

Energy Technology Data Exchange (ETDEWEB)

Liu, Guopeng; Liu, Bing; Wang, Weimin; Zhang, Jian; Athalye, Rahul A.; Moser, Dave; Crowe, Eliot; Bengtson, Nick; Effinger, Mark; Webster, Lia; Hatten, Mike

2011-09-27

The Advanced Energy Retrofit Guide for Office Buildings is a component of the Department of Energy’s Advanced Energy Retrofit Guides for Existing Buildings series. The aim of the guides is to facilitate a rapid escalation in the number of energy efficiency projects in existing buildings and to enhance the quality and depth of those projects. By presenting general project planning guidance as well as financial payback metrics for the most common energy efficiency measures, these guides provide a practical roadmap to effectively planning and implementing performance improvements for existing buildings.

Advanced Energy Retrofit Guide Retail Buildings

Energy Technology Data Exchange (ETDEWEB)

Liu, Guopeng; Liu, Bing; Zhang, Jian; Wang, Weimin; Athalye, Rahul A.; Moser, Dave; Crowe, Eliot; Bengtson, Nick; Effinger, Mark; Webster, Lia; Hatten, Mike

2011-09-19

The Advanced Energy Retrofit Guide for Retail Buildings is a component of the Department of Energy’s Advanced Energy Retrofit Guides for Existing Buildings series. The aim of the guides is to facilitate a rapid escalation in the number of energy efficiency projects in existing buildings and to enhance the quality and depth of those projects. By presenting general project planning guidance as well as financial payback metrics for the most common energy efficiency measures, these guides provide a practical roadmap to effectively planning and implementing performance improvements for existing buildings.

A United States marine presenting with hemoptysis after push-ups.

Science.gov (United States)

Thurber, John S; Unger, Jason A; DeVries, William C

2014-04-01

We present an unusual case of right lower lobe intralobar pulmonary sequestration in a previously healthy and physical active 27-year-old U.S. Marine, who presented with new onset hemoptysis after doing push-ups. Diagnosis was obtained by chest X-ray and contrast computed tomography scan. Preoperatively the patient underwent fluoroscopy-guided embolization of the aberrant systemic artery supplying the sequestration. The segmental resection of the sequestration was then successfully performed through a muscle-sparing thoracotomy. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.

Activity-guided separation of Chromolaena odorata leaf extract reveals fractions with rice disease-reducing properties

DEFF Research Database (Denmark)

Rodriguez Algaba, Julian; Sørensen, Jens Christian; Sørensen, Hilmer

2015-01-01

with water and methanol and the extracts separated using a group separation system followed by analysis using capillary electrophoresis. The fractions from the extracts were tested in vitro and in planta using Bipolaris oryzae (cause of brown spot of rice) to test for their potential to reduce disease...... severity. Activity-guided separation of the C. odorata extracts indicated that compounds with activity could, at least partly, be isolated on a weakly acidic cation exchange column. Further purification yielded fractions with disease reducing effects of up to 72 % at 15 days after inoculation. Activity...... was found both in methanol and water extracts, indicating that the bioactive compound(s) are hydrophilic, low molecular weight compounds. The disease-reducing fractions did not display any direct antimicrobial effects, but data indicate that they protect the plants by induced resistance as evidenced from...

Light Guide Collector Prototype: Laboratory Testing

OpenAIRE

Jitka - Mohelnikova; Stanislav Darula; Ayodeji Omishore; Petr Mohelnik; Denis Micek

2017-01-01

The article reviews the potential of light guide system equipped by a concentrator device capturing daylight applicable for illumination of building interiors and presents results of experiments on performance of its prototype. The main goal is focused on the comparison of traditional solutions and newly developed prototype of the light guide system and presents examination of its light transmission efficiency based on the laboratory experiments.

Consistent guiding center drift theories

International Nuclear Information System (INIS)

Wimmel, H.K.

1982-04-01

Various guiding-center drift theories are presented that are optimized in respect of consistency. They satisfy exact energy conservation theorems (in time-independent fields), Liouville's theorems, and appropriate power balance equations. A theoretical framework is given that allows direct and exact derivation of associated drift-kinetic equations from the respective guiding-center drift-orbit theories. These drift-kinetic equations are listed. Northrop's non-optimized theory is discussed for reference, and internal consistency relations of G.C. drift theories are presented. (orig.)

Living in Space. Book II. Levels D, E, F for Grades 4, 5, 6. Operation Liftoff: Elementary School Space Program. A Resource Guide with Activities for Elementary School Teachers.

Science.gov (United States)

Andrews, Sheila Briskin; Kirschenbaum, Audrey

This guide contains teacher background information and activities for students which deal with space travel and is designed to encourage elementary school students to take a greater interest in mathematics and science. The activities in this guide are to be used with grades 4 to 6 and cover the topics of food, clothing, health, housing,…

Living in Space. Book 1. Levels A, B, C for Grades 1, 2, 3. Operation Liftoff: Elementary School Space Program. A Resource Guide with Activities for Elementary School Teachers.

Science.gov (United States)

Andrews, Sheila Briskin; Kirschenbaum, Audrey

This guide contains teacher background information and activities for students that relate to space travel and is designed to encourage elementary school students to take a greater interest in mathematics and science. The activities in this guide are to be used with grades 1 to 3 and cover the topics of food, clothing, health, housing,…

Memory-guided attention during active viewing of edited dynamic scenes.

Science.gov (United States)

Valuch, Christian; König, Peter; Ansorge, Ulrich

2017-01-01

Films, TV shows, and other edited dynamic scenes contain many cuts, which are abrupt transitions from one video shot to the next. Cuts occur within or between scenes, and often join together visually and semantically related shots. Here, we tested to which degree memory for the visual features of the precut shot facilitates shifting attention to the postcut shot. We manipulated visual similarity across cuts, and measured how this affected covert attention (Experiment 1) and overt attention (Experiments 2 and 3). In Experiments 1 and 2, participants actively viewed a target movie that randomly switched locations with a second, distractor movie at the time of the cuts. In Experiments 1 and 2, participants were able to deploy attention more rapidly and accurately to the target movie's continuation when visual similarity was high than when it was low. Experiment 3 tested whether this could be explained by stimulus-driven (bottom-up) priming by feature similarity, using one clip at screen center that was followed by two alternative continuations to the left and right. Here, even the highest similarity across cuts did not capture attention. We conclude that following cuts of high visual similarity, memory-guided attention facilitates the deployment of attention, but this effect is (top-down) dependent on the viewer's active matching of scene content across cuts.

Community Living Skills Guide: Cooking/Food Preparation.

Science.gov (United States)

Nickovich, Marti; Kreps, Alice Roelofs

One of twenty course guides in the Community Living Skills Guide for the College for Living series, this document provides guidelines and workbook activities for the course, Cooking/Food Preparation. The series of courses for developmentally disabled adults is intended to supplement residential programs and to aid in orienting institutionalized…

Sport and active recreation injuries in Australia: evidence from emergency department presentations.

Science.gov (United States)

Finch, C; Valuri, G; Ozanne-Smith, J

1998-09-01

Despite the rise in specialist clinical services for the management of sports and active recreation injury, many patients attend hospital emergency departments for treatment. The purpose of this study was to describe sports injury cases presented to selected hospital emergency departments around Australia for the period 1989-1993. Routinely collected emergency department injury presentation data from the Australian National Injury Surveillance Unit were examined. Data on 98,040 sports and active recreation emergency department presentations were analysed. Sports and active recreation activities were ranked according to frequency of presentation. Relative proportions of injury type and body region injured were determined. Data are presented separately for children (15 years of age). Among the 10 activities that most commonly led to a sports or active recreation injury presentation for all ages were cycling, Australian football, basketball, soccer, cricket, netball, and rugby. For children, injuries were also commonly associated with roller skating/blading, skateboarding, and trampolining. Hockey, martial arts, and dancing injuries were frequent in adults. Most sporting injuries occurred during organised competition or practice whereas the active recreation injuries occurred in a variety of settings. Fractures, strains, and sprains, particularly to the lower and upper extremities, were common types of injury. The rich, but nevertheless limited, information available about sports and active recreation injuries from data collected in emergency departments indicates that these activities are a common context for injury at the community level in Australia.

Sport and active recreation injuries in Australia: evidence from emergency department presentations

Science.gov (United States)

Finch, C.; Valuri, G.; Ozanne-Smith, J.

1998-01-01

OBJECTIVE: Despite the rise in specialist clinical services for the management of sports and active recreation injury, many patients attend hospital emergency departments for treatment. The purpose of this study was to describe sports injury cases presented to selected hospital emergency departments around Australia for the period 1989-1993. METHODS: Routinely collected emergency department injury presentation data from the Australian National Injury Surveillance Unit were examined. Data on 98,040 sports and active recreation emergency department presentations were analysed. Sports and active recreation activities were ranked according to frequency of presentation. Relative proportions of injury type and body region injured were determined. Data are presented separately for children (15 years of age). RESULTS: Among the 10 activities that most commonly led to a sports or active recreation injury presentation for all ages were cycling, Australian football, basketball, soccer, cricket, netball, and rugby. For children, injuries were also commonly associated with roller skating/blading, skateboarding, and trampolining. Hockey, martial arts, and dancing injuries were frequent in adults. Most sporting injuries occurred during organised competition or practice whereas the active recreation injuries occurred in a variety of settings. Fractures, strains, and sprains, particularly to the lower and upper extremities, were common types of injury. CONCLUSION: The rich, but nevertheless limited, information available about sports and active recreation injuries from data collected in emergency departments indicates that these activities are a common context for injury at the community level in Australia. 


 PMID:9773170

Treatment of osteoid osteoma using CT-guided radiofrequency ablation versus MR-guided laser ablation: A cost comparison

International Nuclear Information System (INIS)

Maurer, M.H.; Gebauer, B.; Wieners, G.; De Bucourt, M.; Renz, D.M.; Hamm, B.; Streitparth, F.

2012-01-01

Objective: To compare the costs of CT-guided radiofrequency ablation (RFA) and MR-guided laser ablation (LA) for minimally invasive percutaneous treatment of osteoid osteoma. Materials and methods: Between November 2005 and October 2011, 20 patients (14 males, 6 females, mean age 20.3 ± 9.1 years) underwent CT-guided RFA and 24 patients (18 males, 6 females; mean age, 23.8 ± 13.8 years) MR-guided LA (open 1.0 Tesla, Panorama HFO, Philips, Best, Netherlands) for osteoid osteoma diagnosed on the basis of clinical presentation and imaging findings. Prorated costs of equipment use (purchase, depreciation, and maintenance), staff costs, and expenditure for disposables were identified for CT-guided RFA and MR-guided LA procedures. Results: The average total costs per patient were EUR 1762 for CT-guided RFA and EUR 1417 for MR-guided LA. These were (RFA/LA) EUR 92/260 for equipment use, EUR 149/208 for staff, and EUR 870/300 for disposables. Conclusion: MR-guided LA is less expensive than CT-guided RFA for minimally invasive percutaneous ablation of osteoid osteoma. The higher costs of RFA are primarily due to the higher price of the disposable RFA probes.

Guided self-organization inception

CERN Document Server

2014-01-01

Is it possible to guide the process of self-organisation towards specific patterns and outcomes?  Wouldn’t this be self-contradictory?   After all, a self-organising process assumes a transition into a more organised form, or towards a more structured functionality, in the absence of centralised control.  Then how can we place the guiding elements so that they do not override rich choices potentially discoverable by an uncontrolled process?  This book presents different approaches to resolving this paradox.  In doing so, the presented studies address a broad range of phenomena, ranging from autopoietic systems to morphological computation, and from small-world networks to information cascades in swarms.  A large variety of methods is employed, from spontaneous symmetry breaking to information dynamics to evolutionary algorithms, creating a rich spectrum reflecting this emerging field. Demonstrating several foundational theories and frameworks, as well as innovative practical implementations, Guided S...

Automotive Mechanics. Student Learning Guides.

Science.gov (United States)

Ridge Vocational-Technical Center, Winter Haven, FL.

These 33 learning guides are self-instructional packets for 33 tasks identified as essential for performance on an entry-level job in automotive mechanics. Each guide is based on a terminal performance objective (task) and 1-9 enabling objectives. For each enabliing objective, some or all of these materials may be presented: learning steps…

Core management and fuel handling for nuclear power plants. Safety guide

International Nuclear Information System (INIS)

2004-01-01

This Safety Guide supplements and elaborates upon the safety requirements for core management and fuel handling that are presented in Section 5 of the Safety Requirements publication on the operation of nuclear power plants. The present publication supersedes the IAEA Safety Guide on Safety Aspects of Core Management and Fuel Handling, issued in 1985 as Safety Series No. 50-SG-010. It is also related to the Safety Guide on the Operating Organization for Nuclear Power Plants, which identifies fuel management as one of the various functions to be performed by the operating organization. The purpose of this Safety Guide is to provide recommendations for core management and fuel handling at nuclear power plants on the basis of current international good practice. The present Safety Guide addresses those aspects of fuel management activities that are necessary in order to allow optimum reactor core operation without compromising the limits imposed by the design safety considerations relating to the nuclear fuel and the plant as a whole. In this publication, 'core management' refers to those activities that are associated with fuel management in the core and reactivity control, and 'fuel handling' refers to the movement, storage and control of fresh and irradiated fuel. Fuel management comprises both core management and fuel handling. This Safety Guide deals with fuel management for all types of land based stationary thermal neutron power plants. It describes the safety objectives of core management, the tasks that have to be accomplished to meet these objectives and the activities undertaken to perform those tasks. It also deals with the receipt of fresh fuel, storage and handling of fuel and other core components, the loading and unloading of fuel and core components, and the insertion and removal of other reactor materials. In addition, it deals with loading a transport container with irradiated fuel and its preparation for transport off the site. Transport

Core management and fuel handling for nuclear power plants. Safety guide

International Nuclear Information System (INIS)

2002-01-01

This Safety Guide supplements and elaborates upon the safety requirements for core management and fuel handling that are presented in Section 5 of the Safety Requirements publication on the operation of nuclear power plants. The present publication supersedes the IAEA Safety Guide on Safety Aspects of Core Management and Fuel Handling, issued in 1985 as Safety Series No. 50-SG-010. It is also related to the Safety Guide on the Operating Organization for Nuclear Power Plants, which identifies fuel management as one of the various functions to be performed by the operating organization. The purpose of this Safety Guide is to provide recommendations for core management and fuel handling at nuclear power plants on the basis of current international good practice. The present Safety Guide addresses those aspects of fuel management activities that are necessary in order to allow optimum reactor core operation without compromising the limits imposed by the design safety considerations relating to the nuclear fuel and the plant as a whole. In this publication, 'core management' refers to those activities that are associated with fuel management in the core and reactivity control, and 'fuel handling' refers to the movement, storage and control of fresh and irradiated fuel. Fuel management comprises both core management and fuel handling. This Safety Guide deals with fuel management for all types of land based stationary thermal neutron power plants. It describes the safety objectives of core management, the tasks that have to be accomplished to meet these objectives and the activities undertaken to perform those tasks. It also deals with the receipt of fresh fuel, storage and handling of fuel and other core components, the loading and unloading of fuel and core components, and the insertion and removal of other reactor materials. In addition, it deals with loading a transport container with irradiated fuel and its preparation for transport off the site. Transport

[Participatory design guide for mental health promotion in prisons].

Science.gov (United States)

Bustamante Navarro, R; Paredes-Carbonell, J J; Aviñó Juan-Ulpiano, D; González Rubio, J; Pitarch Monzó, C; Martínez Martínez, L; Arroyo-Cobo, J M

2013-01-01

[corrected] The main aim was to describe the issues and the participatory process required to design a Guide to promotemental health in prison through group activities. We reviewed the bibliography, the mental health policies, the workshops about healthy mental habits, and a video about protection and risk factors. We identified the stakeholders and sought their points of view about the topics included in the Guide. We decided on the contents of the Guide and the incorporation of the health assets model and the perspectives provided by gender and cultural diversity. After the initial design of the modules and sessions, we started a pilot in the Prison of Valencia and the Prison of Zaragoza with women and men from different cultures, incorporating the suggested improvements, unifying contents and the discursive style. The guide is formed by: a preface, introduction, description, modules, sessions and evaluation. It has 6 modules and 19 sessions on: health and motivation; self-esteem; health and emotions; more assets to improve health: relax, positive thinking, keeping calm, communication and problem resolution; progress is possible: resiliency and starring in my own change. Each session consists of: activities (objectives, material, allocated time and development), theoretical material and tabbed sheets for activities. The guide is available in print and online versions. A guide has been elaborated with involved stakeholders and the opinion of the prison population.

The Art of Buddhism. A Teacher's Guide.

Science.gov (United States)

Forsgren, Krista; Benskin, Elizabeth

While the art of Buddhism has an enduring tradition throughout Asia, this teaching guide focuses on the cultures of three countries in which the Smithsonian's Freer and Sackler Galleries' collections are particularly strong: India, China, and Japan. The guide identifies grade level appropriateness for some lessons and activities. It contains 15…

NORM - practical guide; NORM - guia pratico

Energy Technology Data Exchange (ETDEWEB)

Reis, Rocio dos (ed.)

2016-07-01

The experience of the authors and a literature review on the evaluation of national and international regulatory guides are presented. The objective is to help understand the need to implement the best practices for NORM management in the industries that produce the NORM wastes. The book should act as a reference point, basic, friendly and useful to assist the reader in NORM management activities. The reader should be warned that management requires consultation and involvement of a significant number of stakeholders, in addition to the approval of competent authorities. A list and the technical biography of the authors are also described.

Auditor's Guide to IT Auditing

CERN Document Server

Cascarino, Richard E

2012-01-01

Step-by-step guide to successful implementation and control of IT systems—including the Cloud Many auditors are unfamiliar with the techniques they need to know to efficiently and effectively determine whether information systems are adequately protected. Now in a Second Edition, Auditor's Guide to IT Auditing presents an easy, practical guide for auditors that can be applied to all computing environments.Follows the approach used by the Information System Audit and Control Association's model curriculum, making this book a practical approach to IS auditingServes as an excellent study gu

Light Guide Collector Prototype: Laboratory Testing

Directory of Open Access Journals (Sweden)

Jitka - Mohelnikova

2017-12-01

Full Text Available The article reviews the potential of light guide system equipped by a concentrator device capturing daylight applicable for illumination of building interiors and presents results of experiments on performance of its prototype. The main goal is focused on the comparison of traditional solutions and newly developed prototype of the light guide system and presents examination of its light transmission efficiency based on the laboratory experiments.

International Buyers' guide 1978

International Nuclear Information System (INIS)

Anon.

1978-01-01

A guide is presented of manufactures, consultants, architect engineers and specialist service companies in the nuclear industry. The guide which is in three sections, supplies the following information: addresses of principal national and international agencies and nuclear organisations; addresses etc of companies in all major countries serving the nuclear industry; a list classified in terms of products and services and grouped according to country showing in which fields the companies operate. (author)

Preparation of guides, on mechanics of fluids, for the physics teaching based on the investigatory methodology

Energy Technology Data Exchange (ETDEWEB)

Munoz, Loreto Mora; Buzzo, Ricardo; Martinez-Mardones, Javier; Romero, Angel [Instituto de Fisica, Pontificia Universidad Catolica de Valparaiso Av. Brasil 2950, Valparaiso (Chile)], E-mail: jmartine@ucv.cl

2008-11-01

The challenges in the present educational reform emphasize the professional character of the teacher in the planning of classes, execution of activities and evaluation of learning. A set of planned activities is not to a class of science as a pile of thrown bricks is to a house; this is, that if it is not counted on the knowledge of the preconceptions of the students, the daily realities that they face and of the expectations that these have at the time of participating in the science classes, cannot be obtained the proposed objectives. The well-known investigatory method applied to the education of sciences approaches the conceptual contents from practical activities of easy reproduction that are guided in effective form towards the topics to teach. Guides OPPS (Operation Primary Physics Science), of Louisiana University, are excellent examples of the application of this methodology, as much in the material that corresponds to the students as in the material for the guide of the learning activities (call Leader of the class). This international experience, within the framework used of the Plans and Programs of the Ministry of Education of Chile (MINEDUC), is the main axis of this work in which the accomplishment of guides with this methodology considers, approaching contained of a unit of the common plan of physics for third grade of high school.

Preparation of guides, on mechanics of fluids, for the physics teaching based on the investigatory methodology

International Nuclear Information System (INIS)

Munoz, Loreto Mora; Buzzo, Ricardo; Martinez-Mardones, Javier; Romero, Angel

2008-01-01

The challenges in the present educational reform emphasize the professional character of the teacher in the planning of classes, execution of activities and evaluation of learning. A set of planned activities is not to a class of science as a pile of thrown bricks is to a house; this is, that if it is not counted on the knowledge of the preconceptions of the students, the daily realities that they face and of the expectations that these have at the time of participating in the science classes, cannot be obtained the proposed objectives. The well-known investigatory method applied to the education of sciences approaches the conceptual contents from practical activities of easy reproduction that are guided in effective form towards the topics to teach. Guides OPPS (Operation Primary Physics Science), of Louisiana University, are excellent examples of the application of this methodology, as much in the material that corresponds to the students as in the material for the guide of the learning activities (call Leader of the class). This international experience, within the framework used of the Plans and Programs of the Ministry of Education of Chile (MINEDUC), is the main axis of this work in which the accomplishment of guides with this methodology considers, approaching contained of a unit of the common plan of physics for third grade of high school.

Stimulating Creative Writing Through Literature: A Guide for Teachers of the Intermediate Grades.

Science.gov (United States)

Pilon, Alice Barbara Cummings

A structured writing program for the intermediate grades was designed, utilizing such children's literature as poems, legends, fairy tales, tall tales, and books to stimulate elementary school children to write creatively. Chapters in the teacher's guide for the program present many specific suggestions and activities to help children (1) use…

Electric motor predictive and preventive maintenance guide

International Nuclear Information System (INIS)

Oliver, J.A.

1992-07-01

Electric motor performance is vital to the reliable and efficient operation of power plants. The failure of one or more critical motors could cause lost capacity and excessive repair and maintenance cost. However, existing maintenance recommendations proposed by vendors for electric motors have sometimes encouraged many overly conservative maintenance practices. These practices have lead to excessive maintenance activities and costs which have provided no extra margin of operability. EPRI has sponsored RP2814-35 to develop a guide which provides power plants with information and guidance for establishing an effective maintenance program which will aid in preventing unexpected motor failures and assist in planning motor maintenance efforts. The guide includes a technical description which summarizes technical data relative to the four basic types of motors and their components in general use in power plants. The significant causes of motor failures are investigated and described in detail and methods to optimize service life and minimize maintenance cost through appropriate preventive maintenance and conditioning program are presented. This guide provides a foundation for an effective electric motor maintenance program and simplifies the selection of predictive and preventive maintenance tasks. Its use will enable maintenance personnel in nuclear and fossil plants to plan motor repairs during scheduled outages and avoid costly unexpected failures

A Revised Guide for Improving Teacher Education in Human Rights.

Science.gov (United States)

Phi Delta Kappa, Bloomington, IN. Commission of Education, Human Rights, and Responsibilities.

This document serves as a guide for teacher education institutions and programs designed to prepare educators for meeting their responsibilities in the area of human rights and human relations. This second edition of the guide represents a substantial modification of the original guide, and includes many activities, experiences, and suggestions…

Standard Guide for Environmental Monitoring Plans for Decommissioning of Nuclear Facilities

CERN Document Server

American Society for Testing and Materials. Philadelphia

2010-01-01

1.1 This guide covers the development or assessment of environmental monitoring plans for decommissioning nuclear facilities. This guide addresses: (1) development of an environmental baseline prior to commencement of decommissioning activities; (2) determination of release paths from site activities and their associated exposure pathways in the environment; and (3) selection of appropriate sampling locations and media to ensure that all exposure pathways in the environment are monitored appropriately. This guide also addresses the interfaces between the environmental monitoring plan and other planning documents for site decommissioning, such as radiation protection, site characterization, and waste management plans, and federal, state, and local environmental protection laws and guidance. This guide is applicable up to the point of completing D&D activities and the reuse of the facility or area for other purposes.

Identification of Lilial as a fragrance sensitizer in a perfume by bioassay-guided chemical fractionation and structure-activity relationships

DEFF Research Database (Denmark)

Arnau, E G; Andersen, Klaus Ejner; Bruze, M

2000-01-01

Fragrance materials are among the most common causes of allergic contact dermatitis. The aim of this study was to identify in a perfume fragrance allergens not included in the fragrance mix, by use of bioassay-guided chemical fractionation and chemical analysis/structure-activity relationships...... (SARs). The basis for the investigation was a 45-year-old woman allergic to her own perfume. She had a negative patch test to the fragrance mix and agreed to participate in the study. Chemical fractionation of the perfume concentrate was used for repeated patch testing and/or repeated open application......" in their chemical structure, indicating an ability to modify skin proteins and thus behave as a skin sensitizer, were tested on the patient. The patient reacted positively to the synthetic fragrance p-t-butyl-alpha-methylhydrocinnamic aldehyde (Lilial), a widely used fragrance compound not present in the fragrance...

Living in Style: A Guide to American Architecture.

Science.gov (United States)

Instructor, 1990

1990-01-01

Studying architectural styles is an exciting way to make history come alive and to help students feel a part of their community. This teacher's guide includes several classroom activities, a historical guide to American architectural styles, a list of resources, and a reproducible student worksheet. (IAH)

Conduct of Operations at Nuclear Power Plants. Safety Guide (Spanish Edition)

International Nuclear Information System (INIS)

2012-01-01

This Safety Guide identifies the main responsibilities and practices of nuclear power plant (NPP) operations departments in relation to their responsibility for the safe functioning of the plant. The guide presents the factors to be considered in structuring the operations department of an NPP; setting high standards of performance; making safety related decisions in an effective manner; conducting control room and field activities in a thorough and professional manner; and maintaining an NPP within established operational limits and conditions. Contents: 1. Introduction; 2. Management and organization of plant operations; 3. Shift complement and functions; 4. Shift routines and operating practices; 5. Control of equipment and plant status; 6. Operations equipment and operator aids; 7. Work control and authorization.

Technical innovation: Wire guided ductography

International Nuclear Information System (INIS)

Aslam, Muhammad Ovais; Ramadan, Salwa; Al-Adwani, Muneera

2012-01-01

To introduce an easy and improved technique for performing ductography using inexpensive easily available intravenous cannula. Guide wire: Prolene/Surgipro 3-0 (Polypropylene mono filament non-absorbable surgical suture). A plastic 26 G intravenous cannula. Disposable syringe 2 ml. Non-ionic contrast (low density like Omnipaque 240 mg I/I). The guide wire (Prolene 3-0) is introduced into the orifice of the duct heaving discharge and 26 G intravenous plastic cannula is then passed over the guide wire. The cannula is advanced in the duct over guide wire by spinning around it. When the cannula is in place the guide wire is removed. Any air bubbles present in the hub of the cannula can be displaced by filling the hub from bottom upwards with needle attached to contrast filled syringe. 0.2–0.4 ml non-ionic contrast is gently injected. Injection is stopped if the patient has pain or burning. Magnified cranio-caudal view is obtained with cannula tapped in place and gentle compression is applied with the patient sitting. If duct filling is satisfactory a 90* lateral view is obtained. A successful adaptation of the technique for performing ductography is presented. The materials required for the technique are easily available in most radiology departments and are inexpensive, thus making the procedure comfortable for the patient and radiologist with considerable cost effectiveness.

COATING ALTERNATIVES GUIDE (CAGE) USER'S GUIDE

Science.gov (United States)

The guide provides instructions for using the Coating Alternatives GuidE (CAGE) software program, version 1.0. It assumes that the user is familiar with the fundamentals of operating an IBM-compatible personal computer (PC) under the Microsoft disk operating system (MS-DOS). CAGE...

RNA-guided transcriptional activation via CRISPR/dCas9 mimics overexpression phenotypes in Arabidopsis.

Directory of Open Access Journals (Sweden)

Jong-Jin Park

Full Text Available Clustered regularly interspaced short palindromic repeats (CRISPR and the CRISPR associated protein 9 (Cas9 system allows effective gene modification through RNA-guided DNA targeting. The Cas9 has undergone a series of functional alterations from the original active endonuclease to partially or completely deactivated Cas9. The catalytically deactivated Cas9 (dCas9 offers a platform to regulate transcriptional expression with the addition of activator or repressor domains. We redesigned a CRISPR/Cas9 activation system by adding the p65 transactivating subunit of NF-kappa B and a heat-shock factor 1 (HSF activation domain to dCas9 bound with the VP64 (tetramer of VP16 activation domain for application in plants. The redesigned CRISPR/Cas9 activation system was tested in Arabidopsis to increase endogenous transcriptional levels of production of anthocyanin pigment 1 (PAP1 and Arabidopsis thaliana vacuolar H+-pyrophosphatase (AVP1. The expression of PAP1 was increased two- to three-fold and the activated plants exhibited purple leaves similar to that of PAP1 overexpressors. The AVP1 gene expression was increased two- to five-fold in transgenic plants. In comparison to the wild type, AVP1 activated plants had increased leaf numbers, larger single-leaf areas and improved tolerance to drought stress. The AVP1 activated plants showed similar phenotypes to AVP1 overexpressors. Therefore, the redesigned CRISPR/Cas9 activation system containing modified p65-HSF provides a simple approach for producing activated plants by upregulating endogenous transcriptional levels.

THE EFFECTIVENESS OF CTL MODEL GUIDED INQUIRI-BASED IN THE TOPIC OF CHEMICALS IN DAILY LIFE TO IMPROVE STUDENTS’ LEARNING OUTCOMES AND ACTIVENESS

OpenAIRE

N. R. Fitriani; A. Widiyatmoko; M. Khusniati

2016-01-01

Science learning in school can be applied by connecting the material in the learning with real life. However in fact science learning process in SMP Negeri 10 Magelang has not emphasized students’ activity to relate science to real life. Learning science using CTL guided inquiry-based model implement the learning in where teacher provides initial questions related issues or events in everyday life, then students do experiments to prove concepts of science guided by teacher.The purpose of this...

Treatment of child anxiety disorders via guided parent-delivered cognitive-behavioural therapy: randomised controlled trial.

Science.gov (United States)

Thirlwall, Kerstin; Cooper, Peter J; Karalus, Jessica; Voysey, Merryn; Willetts, Lucy; Creswell, Cathy

2013-12-01

Promising evidence has emerged of clinical gains using guided self-help cognitive-behavioural therapy (CBT) for child anxiety and by involving parents in treatment; however, the efficacy of guided parent-delivered CBT has not been systematically evaluated in UK primary and secondary settings. To evaluate the efficacy of low-intensity guided parent-delivered CBT treatments for children with anxiety disorders. A total of 194 children presenting with a current anxiety disorder, whose primary carer did not meet criteria for a current anxiety disorder, were randomly allocated to full guided parent-delivered CBT (four face-to-face and four telephone sessions) or brief guided parent-delivered CBT (two face-to-face and two telephone sessions), or a wait-list control group (trial registration: ISRCTN92977593). Presence and severity of child primary anxiety disorder (Anxiety Disorders Interview Schedule for DSM-IV, child/parent versions), improvement in child presentation of anxiety (Clinical Global Impression - Improvement scale), and change in child anxiety symptoms (Spence Children's Anxiety Scale, child/parent version and Child Anxiety Impact scale, parent version) were assessed at post-treatment and for those in the two active treatment groups, 6 months post-treatment. Full guided parent-delivered CBT produced superior diagnostic outcomes compared with wait-list at post-treatment, whereas brief guided parent-delivered CBT did not: at post-treatment, 25 (50%) of those in the full guided CBT group had recovered from their primary diagnosis, compared with 16 (25%) of those on the wait-list (relative risk (RR) 1.85, 95% CI 1.14-2.99); and in the brief guided CBT group, 18 participants (39%) had recovered from their primary diagnosis post-treatment (RR = 1.56, 95% CI 0.89-2.74). Level of therapist training and experience was unrelated to child outcome. Full guided parent-delivered CBT is an effective and inexpensive first-line treatment for child anxiety.

Three-dimensional plotting and printing of an implant drilling guide: simplifying guided implant surgery.

Science.gov (United States)

Flügge, Tabea Viktoria; Nelson, Katja; Schmelzeisen, Rainer; Metzger, Marc Christian

2013-08-01

To present an efficient workflow for the production of implant drilling guides using virtual planning tools. For this purpose, laser surface scanning, cone beam computed tomography, computer-aided design and manufacturing, and 3-dimensional (3D) printing were combined. Intraoral optical impressions (iTero, Align Technologies, Santa Clara, CA) and digital 3D radiographs (cone beam computed tomography) were performed at the first consultation of 1 exemplary patient. With image processing techniques, the intraoral surface data, acquired using an intraoral scanner, and radiologic 3D data were fused. The virtual implant planning process (using virtual library teeth) and the in-office production of the implant drilling guide was performed after only 1 clinical consultation of the patient. Implant surgery with a computer-aided design and manufacturing produced implant drilling guide was performed during the second consultation. The production of a scan prosthesis and multiple preoperative consultations of the patient were unnecessary. The presented procedure offers another step in facilitating the production of drilling guides in dental implantology. Four main advantages are realized with this procedure. First, no additional scan prosthesis is needed. Second, data acquisition can be performed during the first consultation. Third, the virtual planning is directly transferred to the drilling guide without a loss of accuracy. Finally, the treatment cost and time required are reduced with this facilitated production process. Copyright © 2013 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Promotion Guide – A guide for career reviews

CERN Multimedia

Staff Association

2017-01-01

On 8 February, the Standing Concertation Committee (SCC) approved the Promotion Guide, subtitled “A guide for career reviews”. The English version is already published on the HR website. This Promotion Guide is not very different from the Career Path Guide which it replaces following the implementation of the new career structure with benchmark jobs and grades. Structure The guide is composed of three parts: Section I – Introduction revisits the reference documents: the Staff Rules and Regulations (S&R) and the Administrative Circular No. 26 (AC 26). In the Staff Rules and Regulations, the term promotion is defined as a change of grade1 and in Administrative Circular No. 26, the Promotion Guide is referenced under paragraph 452. The objective of the Promotion Guide is laid out in Section I: “The Promotion Guide defines the criteria to be used as a reference for career reviews with a view to a potential promotion”. However, this guide do...

Writer`s guide for technical procedures

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-01

A primary objective of operations conducted in the US Department of Energy (DOE) complex is safety. Procedures are a critical element of maintaining a safety envelope to ensure safe facility operation. This DOE Writer`s Guide for Technical Procedures addresses the content, format, and style of technical procedures that prescribe production, operation of equipment and facilities, and maintenance activities. The DOE Writer`s Guide for Management Control Procedures and DOE Writer`s Guide for Emergency and Alarm Response Procedures are being developed to assist writers in developing nontechnical procedures. DOE is providing this guide to assist writers across the DOE complex in producing accurate, complete, and usable procedures that promote safe and efficient operations that comply with DOE orders, including DOE Order 5480.19, Conduct of Operations for DOE Facilities, and 5480.6, Safety of Department of Energy-Owned Nuclear Reactors.

The IAEA's activities in safeguarding nuclear materials and in developing internationally acceptable safety codes and guides for nuclear power plants

International Nuclear Information System (INIS)

Rometsch, Rudolf; Specter, Herschel

1977-01-01

Promoting the peaceful use of nuclear energy and aiming at the international sharing of its benefits are objectives that guide the activities of the Agency. But this promotional work is carried out on condition that security and safety are provided for. All Agency assistance involving nuclear facilities will be subjected to standards of safety or other standards, which are proposed by a State the Agency finds essentially equivalent. Safeguards are always applied on the basis of agreement. States party to NPT are obligated to negotiate and conclude with the Agency agreements which cover all their peaceful nuclear activities. Safeguards agreements concluded outside NPT are applied to specific supplies of facilities, equipment and material. To assist countries in laying down their nuclear safety regulations the Agency's program for the developing of codesof practice and safety guides for nuclear power plants draws up guidelines for governmental organizations, siting, design, operation and quality assurance. Codes are the fundamental documents laying down the objectives of each field of nuclear safety

The Economist guide to management ideas and gurus

CERN Document Server

Hindle, Tom

2008-01-01

This insightful guide, which has proven hugely popular around the world in hardback, not only includes the most significant ideas that have influenced the management of business over the past century, but it also includes entries on the most influential business thinkers of the past and present. Entries on ideas include: Active Inertia; Disruptive Technology; Genchi Genbutsu (Japanese for "Go and See for Yourself"); The Halo Effect; The Long Tail; Pareto Principle; Six Sigma;, Skunkworks; SWOT analysis; Thin Slicing; Tipping Point; Triple Bottom Line.

EDF guide book for decontamination at power plant

International Nuclear Information System (INIS)

Glorennec, C.; Bemer, J.P.

1988-01-01

Nuclear Power Plant components or equipment often need to be more or less decontaminated before undergoing maintenance. In order to coordinate the activities of the different maintenance specialists belonging to the corporate or site organizations, the management of EDF/Nuclear and Fossil Division has created a decontamination task force. One of the objectives of this task force was to elaborate the present Guide Book for Decontamination at Power Plants. This paper provides assistance to nuclear plants operators in the very specific field of decontamination

Regulations and guides for nuclear power plants

International Nuclear Information System (INIS)

1984-01-01

The purpose of the present Guide is to provide information, guidance and recommendations to assist the regulatory body of a Member State in establishing its own regulations and guides. It discusses the purpose, the method and procedure of establishment, and the content and legal status of these documents, and it explains how to use the Codes of Practice and Safety Guides issued by the IAEA under the Nuclear Safety Standards (NUSS) programme. Certain aspects of how to use other international standards and appropriate regulations and guides from other countries are discussed

EPRI's pumped storage planning and evaluation guide

International Nuclear Information System (INIS)

Chen, H.H.

1991-01-01

EPRI's Hydropower Pumped Storage Planning and Evaluation Guide was published in 1990. The Guide provides step-by-step procedures to: evaluate pumped-storage operation in a utility system, establish site development concept, estimate capital cost, and conduct economic analysis. The Guide provides a floppy diskette containing a production costing model simulating the chronologic operation of pumped storage in a generating system. It provides a series of estimating curves for the preparation of capital cost estimates. The paper presents how the Guide was organized and prepared, and highlights its contents

The effectiveness of module based on guided inquiry method to improve students’ logical thinking ability

Science.gov (United States)

Ash-Shiddieqy, M. H.; Suparmi, A.; Sunarno, W.

2018-04-01

The purpose of this research is to understand the effectiveness of module based on guided inquiry method to improve students’ logical thinking ability. This research only evaluate the students’ logical ability after follows the learning activities that used developed physics module based on guided inquiry method. After the learning activities, students This research method uses a test instrument that adapts TOLT instrument. There are samples of 68 students of grade XI taken from SMA Negeri 4 Surakarta.Based on the results of the research can be seen that in the experimental class and control class, the posttest value aspect of probabilistic reasoning has the highest value than other aspects, whereas the posttest value of the proportional reasoning aspect has the lowest value. The average value of N-gain in the experimental class is 0.39, while in the control class is 0.30. Nevertheless, the N-gain values obtained in the experimental class are larger than the control class, so the guided inquiry-based module is considered more effective for improving students’ logical thinking. Based on the data obtained from the research shows the modules available to help teachers and students in learning activities. The developed Physics module is integrated with every syntax present in guided inquiry method, so it can be used to improve students’ logical thinking ability.

FFTF operations procedures preparation guide. Revision 2

International Nuclear Information System (INIS)

1976-12-01

The Guide is intended to provide guidelines for the initial preparation of FFTF Operating Procedures. The Procedures Preparation Guide was developed from the plan presented and approved in the FFTF Reactor Plant Procedures Plan, PC-1, Revision 3

Users guide for the ANL IBM SPx

Energy Technology Data Exchange (ETDEWEB)

Gropp, W.; Lusk, E.

1994-12-01

This guide presents the features of the IBM SPx installed in the Mathematics and Computer Science Division at Argonne National Laboratory. The guide describes the available hardware and software, access policies, and hints for using the system productively.

Mathematics: Foundations for Business. Instructor's Guide.

Science.gov (United States)

Hopfe, Manfred W.; Bianci-Rossi, Larry

This is the instructor's guide to a text designed for the contemporary business student who frequently questions the need for studying mathematics. The text material is presented in a "building-block" fashion, with skills learned in earlier chapters organized to provide a smooth transition into more difficult topics. This guide consists…

Preliminary standard review guide for Environmental Restoration/Decontamination and Decommissioning safety analyses

International Nuclear Information System (INIS)

Ellingson, D.R.

1993-06-01

The review guide is based on the shared experiences, approaches, and philosophies of the Environmental Restoration/Decontamination and Decommissioning (ER/D ampersand D) subgroup members. It is presented in the form of a review guide to maximize the benefit to both the safety analyses practitioner and reviewer. The guide focuses on those challenges that tend to be unique to ER/D ampersand D cleanup activities. Some of these experiences, approaches, and philosophies may find application or be beneficial to a broader spectrum of activities such as terminal cleanout or even new operations. Challenges unique to ER/D ampersand D activities include (1) consent agreements requiring activity startup on designated dates; (2) the increased uncertainty of specific hazards; and (3) the highly variable activities covered under the broad category of ER/D ampersand D. These unique challenges are in addition to the challenges encountered in all activities; e.g., new and changing requirements and multiple interpretations. The experiences in approaches, methods, and solutions to the challenges are documented from the practitioner and reviewer's perspective, thereby providing the viewpoints on why a direction was taken and the concerns expressed. Site cleanup consent agreements with predetermined dates for restoration activity startup add the dimension of imposed punitive actions for failure to meet the date. Approval of the safety analysis is a prerequisite to startup. Actions that increase expediency are (1) assuring activity safety; (2) documenting that assurance; and (3) acquiring the necessary approvals. These actions increase the timeliness of startup and decrease the potential for punitive action. Improvement in expediency has been achieved by using safety analysis techniques to provide input to the line management decision process rather than as a review of line management decisions. Expediency is also improved by sharing the safety input and resultant decisions with

Visitor Learning on Guided Tours: An Activity Theory Approach

Science.gov (United States)

Robinson, Lily Beatrice

2016-01-01

Guided tours, field trips, and other non-formal learning experiences occur in a variety of settings such as museums, parks, civic buildings, and architectural landmarks for the purpose of educating the public. This study yielded four main findings. (1) Program educational goals were visitor awareness, positive affective experience, and advocacy.…

CNN Newsroom Classroom Guides. September 1-30, 1994.

Science.gov (United States)

Cable News Network, Atlanta, GA.

These classroom guides for the daily CNN (Cable News Network) Newsroom broadcasts for the month of August provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guides include: (1) truce in Northern Ireland, school censorship, scientific method, burial…

Intermittency in Hall-magnetohydrodynamics with a strong guide field

OpenAIRE

Imazio, P. Rodriguez; Martin, L. N.; Dmitruk, P.; Mininni, P. D.

2013-01-01

We present a detailed study of intermittency in the velocity and magnetic field fluctuations of compressible Hall-magnetohydrodynamic turbulence with an external guide field. To solve the equations numerically, a reduced model valid when a strong guide field is present is used. Different values for the ion skin depth are considered in the simulations. The resulting data are analyzed computing field increments in several directions perpendicular to the guide field, and building structure funct...

Tank characterization reference guide

International Nuclear Information System (INIS)

De Lorenzo, D.S.; DiCenso, A.T.; Hiller, D.B.; Johnson, K.W.; Rutherford, J.H.; Smith, D.J.; Simpson, B.C.

1994-09-01

Characterization of the Hanford Site high-level waste storage tanks supports safety issue resolution; operations and maintenance requirements; and retrieval, pretreatment, vitrification, and disposal technology development. Technical, historical, and programmatic information about the waste tanks is often scattered among many sources, if it is documented at all. This Tank Characterization Reference Guide, therefore, serves as a common location for much of the generic tank information that is otherwise contained in many documents. The report is intended to be an introduction to the issues and history surrounding the generation, storage, and management of the liquid process wastes, and a presentation of the sampling, analysis, and modeling activities that support the current waste characterization. This report should provide a basis upon which those unfamiliar with the Hanford Site tank farms can start their research

Solitonic guide and multiphoton absorption processes in photopolymerizable materials for optical integrated circuits

Science.gov (United States)

Klein, Stephane; Barsella, Alberto; Acker, D.; Sutter, C.; Beyer, N.; Andraud, Chantal; Fort, Alain F.; Dorkenoo, Kokou D.

2004-09-01

Up to now, most of the optical integrated devices are realized on glass or III-V substrates and the waveguides are usually obtained by photolithography techniques. We present here a new approach based on the use of photopolymerizable compounds. The conditions of self-written channel creation by solitonic propagation inside the bulk of these photopolymerizable formulations are analyzed. Both experimental and theoretical results of the various stages of self-written guide propagation are presented. A further step has been achieved by using a two-photon absorption process for the polymerization via a confocal microscopy technique. Combined with the solitonic guide creation, this technique allows to draw 3D optical circuits. Finally, by doping the photopolymerizable mixtures with push-pull chromophores having a controlled orientation, it will be possible to create active optical integrated devices.

Image-Guided Cancer Nanomedicine

Directory of Open Access Journals (Sweden)

Dong-Hyun Kim

2018-01-01

Full Text Available Multifunctional nanoparticles with superior imaging properties and therapeutic effects have been extensively developed for the nanomedicine. However, tumor-intrinsic barriers and tumor heterogeneity have resulted in low in vivo therapeutic efficacy. The poor in vivo targeting efficiency in passive and active targeting of nano-therapeutics along with the toxicity of nanoparticles has been a major problem in nanomedicine. Recently, image-guided nanomedicine, which can deliver nanoparticles locally using non-invasive imaging and interventional oncology techniques, has been paid attention as a new opportunity of nanomedicine. This short review will discuss the existing challenges in nanomedicine and describe the prospects for future image-guided nanomedicine.

Guided wave based structural health monitoring: A review

International Nuclear Information System (INIS)

Mitra, Mira; Gopalakrishnan, S

2016-01-01

The paper provides a state of the art review of guided wave based structural health monitoring (SHM). First, the fundamental concepts of guided wave propagation and its implementation for SHM is explained. Following sections present the different modeling schemes adopted, developments in the area of transducers for generation, and sensing of wave, signal processing and imaging technique, statistical and machine learning schemes for feature extraction. Next, a section is presented on the recent advancements in nonlinear guided wave for SHM. This is followed by section on Rayleigh and SH waves. Next is a section on real-life implementation of guided wave for industrial problems. The paper, though briefly talks about the early development for completeness, is primarily focussed on the recent progress made in the last decade. The paper ends by discussing and highlighting the future directions and open areas of research in guided wave based SHM. (topical review)

Standard guide for determining corrosivity of crude oils

CERN Document Server

American Society for Testing and Materials. Philadelphia

2010-01-01

1.1 This guide presents some generally accepted laboratory methodologies that are used for determining the corrosivity of crude oil. 1.2 This guide does not cover detailed calculations and methods, but rather a range of approaches that have found application in evaluating the corrosivity of crude oil. 1.3 Only those methodologies that have found wide acceptance in crude oil corrosivity evaluation are considered in this guide. 1.4 This guide does not address the change in oil/water ratio caused by accumulation of water at low points in a pipeline system. 1.5 This guide is intended to assist in the selection of methodologies that can be used for determining the corrosivity of crude oil under conditions in which water is present in the liquid state (typically up to 100°C). These conditions normally occur during oil and gas production, storage, and transportation in the pipelines. 1.6 This guide does not cover the evaluation of corrosivity of crude oil at higher temperatures (typically above 300°C) that oc...

First Responders Guide to Computer Forensics: Advanced Topics

National Research Council Canada - National Science Library

Nolan, Richard; Baker, Marie; Branson, Jake; Hammerstein, Josh; Rush, Kris; Waits, Cal; Schweinsberg, Elizabeth

2005-01-01

First Responders Guide to Computer Forensics: Advanced Topics expands on the technical material presented in SEI handbook CMU/SEI-2005-HB-001, First Responders Guide to Computer Forensics [Nolan 05...

Hispanic Folk Arts and the Environment: An Interdisciplinary Curriculum Guide. A New Mexican Perspective.

Science.gov (United States)

Lopez, Alejandro

This interdisciplinary, bilingual curriculum resource, contains a 29-minute videotape program, 20 colorplate posters, and a curriculum guide. The resource presents an examination of the folklife and folklore expressions of the Hispanic people of New Mexico. The focus of the curriculum is the relationship of survival-based folk activities to the…

Teacher's Guide for Earthworms.

Science.gov (United States)

Bruno, Merle S.; And Others

This teacher's guide on earthworms includes four major sections: (1) introduction, (2) caring for earthworms in the classroom, (3) classroom activities, and (4) the appendix. The introduction includes information concerning grade level, scheduling, materials, obtaining earthworms, field study, classroom clean-up, and records. Caring for earthworms…

CNN Newsroom Classroom Guides. June 1-30, 1994.

Science.gov (United States)

Cable News Network, Atlanta, GA.

These classroom guides for the daily CNN (Cable News Network) Newsroom broadcasts for the month of June provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Topics covered by the guides include: (1) Congressman Dan Rostenkowski, D-Day, cars and Singapore, Rodney King civil…

[Guided maxillofacial surgery: Simulation and surgery aided by stereolithographic guides and custom-made miniplates.

Science.gov (United States)

Philippe, B

2013-08-05

We present a new model of guided surgery, exclusively using computer assistance, from the preoperative planning of osteotomies to the actual surgery with the aid of stereolithographic cutting guides and osteosynthetic miniplates designed and made preoperatively, using custom-made titanium miniplates thanks to direct metal laser sintering. We describe the principles that guide the designing and industrial manufacturing of this new type of osteosynthesis miniplates. The surgical procedure is described step-by-step using several representative cases of dento-maxillofacial dysmorphosis. The encouraging short-term results demonstrate the wide range of application of this new technology for cranio-maxillofacial surgery, whatever the type of osteotomy performed, and for plastic reconstructive surgery. Copyright © 2013. Published by Elsevier Masson SAS.

Multiple time-reversed guide-sources in shallow water

Science.gov (United States)

Gaumond, Charles F.; Fromm, David M.; Lingevitch, Joseph F.; Gauss, Roger C.; Menis, Richard

2003-10-01

Detection in a monostatic, broadband, active sonar system in shallow water is degraded by propagation-induced spreading. The detection improvement from multiple spatially separated guide sources (GSs) is presented as a method to mitigate this degradation. The improvement of detection by using information in a set of one-way transmissions from a variety of positions is shown using sea data. The experimental area is south of the Hudson Canyon off the coast of New Jersey. The data were taken using five elements of a time-reversing VLA. The five elements were contiguous and at midwater depth. The target and guide source was an echo repeater positioned at various ranges and at middepth. The transmitted signals were 3.0- to 3.5-kHz LFMs. The data are analyzed to show the amount of information present in the collection, a baseline probability of detection (PD) not using the collection of GS signals, the improvement in PD from the use of various sets of GS signals. The dependence of the improvement as a function of range is also shown. [The authors acknowledge support from Dr. Jeffrey Simmen, ONR321OS, and the chief scientist Dr. Charles Holland. Work supported by ONR.

Physical Activity and Pregnancy: Past and Present Evidence and Future Recommendations

Science.gov (United States)

Symons Downs, Danielle; Chasan-Taber, Lisa; Evenson, Kelly R.; Leiferman, Jenn; Yeo, SeonAe

2012-01-01

Purpose: In this review, we provide researchers and practitioners with an overview of the physical activity and pregnancy literature to promote prenatal physical activity, improve measurement, further elucidate the role of activity in reducing maternal health complications, and inform future research. Method: We examined past and present physical…

Review of Pocket Guide Megaliths [app

Directory of Open Access Journals (Sweden)

Barney Harris

2017-09-01

Full Text Available The Pocket Guide Megaliths app was developed by Senet Mobile UK in collaboration with The Megalithic Portal website. The app was released in 2016 and is currently available for iOS devices, such as iPhone and iPads. Pocket Guide Megaliths presents the Megalithic Portal's burgeoning worldwide database of ancient and prehistoric sites in a variety of innovative and engaging ways. It aims to act primarily as a guide to enjoying and exploring the rich prehistoric heritage of the world, though offers additional functionality for would-be monument explorers too.

Radiation protection and safety guide no. GRPB-G-4: inspection

International Nuclear Information System (INIS)

Schandorf, C.; Darko, O.; Yeboah, J.; Osei, E.K.; Asiamah, S.D.

1995-01-01

The use of ionizing radiation and radiation sources in Ghana is on the increase due to national developmental efforts in Health Care, Food and Agriculture, Industry, Science and Technology. This regulatory Guide has been developed to assist both the Regulatory Body (Radiation Protection Board) and operating organizations to perform systematic inspections commensurate with the level of hazard associated with the application of radiation sources and radioactive materials. The present Guide applies to the Radiation Protection and Safety inspection and/or audit conducted by the Radiation Protection Board or Radiation Safety Officer. The present Guide is applicable in Ghana and to foreign suppliers of radiation sources. The present Guide applies to notifying person, licensee, or registrant and unauthorized practice

Elementary Science Resource Guide.

Science.gov (United States)

Texas Education Agency, Austin. Div. of Curriculum Development.

This guide for elementary teachers provides information on getting ideas into action, designing and implementing the right situation, ways in which to evaluate science process activities with students, and seven sample units. The units cover using the senses, magnets, forces, weather forecasting, classification of living things, and the physical…

Incorporation of Socio-scientific Content into Active Learning Activities

Science.gov (United States)

King, D. B.; Lewis, J. E.; Anderson, K.; Latch, D.; Sutheimer, S.; Webster, G.; Moog, R.

2014-12-01

Active learning has gained increasing support as an effective pedagogical technique to improve student learning. One way to promote active learning in the classroom is the use of in-class activities in place of lecturing. As part of an NSF-funded project, a set of in-class activities have been created that use climate change topics to teach chemistry content. These activities use the Process Oriented Guided Inquiry Learning (POGIL) methodology. In this pedagogical approach a set of models and a series of critical thinking questions are used to guide students through the introduction to or application of course content. Students complete the activities in their groups, with the faculty member as a facilitator of learning. Through assigned group roles and intentionally designed activity structure, process skills, such as teamwork, communication, and information processing, are developed during completion of the activity. Each of these climate change activities contains a socio-scientific component, e.g., social, ethical and economic data. In one activity, greenhouse gases are used to explain the concept of dipole moment. Data about natural and anthropogenic production rates, global warming potential and atmospheric lifetimes for a list of greenhouse gases are presented. The students are asked to identify which greenhouse gas they would regulate, with a corresponding explanation for their choice. They are also asked to identify the disadvantages of regulating the gas they chose in the previous question. In another activity, where carbon sequestration is used to demonstrate the utility of a phase diagram, students use economic and environmental data to choose the best location for sequestration. Too often discussions about climate change (both in and outside the classroom) consist of purely emotional responses. These activities force students to use data to support their arguments and hypothesize about what other data could be used in the corresponding discussion to

Guide to ship sanitation

National Research Council Canada - National Science Library

2011-01-01

"The third edition of the Guide to Ship Sanitation presents the public health significance of ships in terms of disease and highlights the importance of applying appropriate control measures"--Back cover...

Inspection and enforcement by the regulatory body for nuclear power plants. A safety guide. A publication within the NUSS programme

International Nuclear Information System (INIS)

1996-01-01

The purpose of this Safety Guide is to provide guidance on fulfilling the requirements for inspection and enforcement by the regulatory body, as set out in the Code on the Safety of Nuclear Power Plants; Governmental Organization. This Safety Guide deals with the responsibilities of the regulatory body, the organization of inspection programmes, the inspection resources of the regulatory body, methods of inspection, requirements on the applicant/licensee in regard to regulatory inspection, inspection reports, and regulatory action and enforcement. It is recognized that many of the provisions of this Safety Guide may be applicable to the regulations of other nuclear facilities and related activities including research reactors, fuel processing and manufacturing plants, irradiated fuel processing plants and radioactive waste management facilities. This Safety Guide does not deal specifically with the functions of a regulatory body responsible for such matters; however, the guidance presented here may be applied as appropriate to these activities. 11 refs, 1 fig

Emotional exhaustion and job satisfaction of tour guides in rural areas

Directory of Open Access Journals (Sweden)

Anđelković Željko

2017-01-01

Full Text Available The purpose of this study was to determinate the job satisfaction and emotional exhaustion of tour guides in rural areas and to show how these two concepts are related to each other. A total of 102 tour guides, who lead tours or have experience in leading tours in rural areas took part in the questionnaire and the results were given and processed in SPSS version 17. Tour guides have a great importance in interpretation of rural areas as well as a significant role in presenting local customs and products in rural tourism. Exploring their satisfaction but also emotional exhaustion is of paramount importance for maintaining their excellence in interpretation of these areas. The results indicate that job satisfaction is still not on satisfying level, while emotional exhaustion is under acceptable limits. The results also showed that there is a negative connection between these two concepts. The obtained data should be beneficial not only to tour-operators but also to other tourism-related companies dealing with FDA (Front Desk Activities and employees in rural tourism: the data about job satisfaction and emotional exhaustion of tour guides can be used in developing management and work motivation strategies. The profound insight in job satisfaction and emotional exhaustion is important in order to achieve business excellence of tour guides in rural areas.

Cycling Injuries Presenting to an Irish Emergency Department

LENUS (Irish Health Repository)

J Foley, J

2016-06-01

There is little published data on cycling injuries in Ireland and the present study aims to describe the cycling related injuries presenting to the emergency department (ED), of a tertiary urban university hospital. This is a retrospective review of cycling-related injuries presenting to the ED of St. Vincent’s University Hospital (SVUH) from 1st of January to 31st of December 2014. There were 534 cycling related injuries presenting to the ED during the study period. Just over 71% of the patients were male, and 14.8% of patients presented following a collision with a motor vehicle. Forty patients required admission to hospital following their injury with 6 of these patients spending time in the intensive care unit. Cycling is now a very popular means of transport and exercise activity in Ireland and using hospital based data, it is possible that EDs may provide a vector for guiding injury prevention strategies in the future

Oh, What a Pane! An Inquiry Based on Activity with a Mathematical Approach to Investigation Windows on Earth...and in Space. Teacher Guide

Science.gov (United States)

Baker, Marshalyn; Mailhot, Michele; Graff, Paige Valderrama

2010-01-01

This is a teacher's guide to assist teachers in developing modules on windows for use in both earth and space and astronaut photographs. Activities incorporating mathematical exercises are suggested for grades five through ten.

Reviewing a Reading Program: Professional Development Module. Facilitator's Guide

Science.gov (United States)

Kosanovich, Marcia; Jordan, Georgia; Arndt, Elissa; VanSciver, Mary; Wahl, Michelle; Rissman, Lila

2008-01-01

This "Facilitator's Guide" has been prepared for presenters of the Reviewing a Reading Program professional development training. It is one of three pieces comprising a suite of materials on reviewing reading programs: this "Guide", the "Reviewing a Reading Program Participant's Guide" and the "Reviewing a Reading Program" Professional Development…

Guide d'exploitation des filières de traitement par boues activées

OpenAIRE

Boutin, C.; Caquel, O.; Dimastromatteo, N.,; Dumaine, J.,; Fernandes. G.,; Gervasi, C.; Parotin, S.; Prost Boucle, S.; Tscherter, C.

2015-01-01

/ Ce guide, à destination des maîtres d'ouvrage et des exploitants, a pour objet de présenter de façon synthétique, les modalités d'exploitation courante d'une station d'épuration par boues activées de capacité < 600 kg DBO5/jour (soit 10 000 équivalents habitants (EH)), et dimensionnée dans le domaine de charge de l'aération prolongée (Cm < 0,1 kg DBO5 /kg MVS/jour). Conçu au fil de l'eau, il recense, tant pour la file eau que pour la file boues, l'ensemble des tâches d'exploitation courante...

Effects of a self-guided, web-based activity programme for patients with persistent musculoskeletal pain in primary healthcare: A randomized controlled trial.

Science.gov (United States)

Calner, T; Nordin, C; Eriksson, M K; Nyberg, L; Gard, G; Michaelson, P

2017-07-01

Web-based interventions for pain management are increasingly used with possible benefits, but never used in addition to multimodal rehabilitation (MMR). MMR is recommended treatment for persistent pain in Sweden. The aim was to evaluate the effects of a self-guided, web-based programme added to MMR for work ability, pain, disability and health-related quality of life. We included 99 participants with persistent musculoskeletal pain in a randomized study with two intervention arms: (1) MMR and web-based intervention, and (2) MMR. Data was collected at baseline, 4 and 12 months. Outcome measures were work ability, working percentage, average pain intensity, pain-related disability, and health-related quality of life. There were no significant effects of adding the web-based intervention to MMR regarding any of the outcome variables. This trial provides no support for adding a self-guided, web-based activity programme to MMR for patients with persistent musculoskeletal pain. The comprehensive self-guided, web-based programme for activity, Web-BCPA, added to multimodal treatment in primary health care had no effect on work ability, pain, disability or health-related quality of life. Future web-based interventions should be tailored to patients' individual needs and expectations. © 2017 European Pain Federation - EFIC®.

Destructive investigations of decommissioned guide tubes: characterization of wear

International Nuclear Information System (INIS)

Ambard, A.; Lina, A.; Bosselut, D.; Deforge, D.; Robinot, P.; Thebault, Y.; Paulhies, M.; Maingot, S.

2011-01-01

The wear of control rods has been a major maintenance concern for EDF since the nineties. Surface treatment of the rods (nitriding, chrome plating) were developed to deal with this issue. However, the question came to know whether the guiding tube in which those new control rods are inserted are also worn. EDF interest into guide tube wear has been renewed by the slow increase of the drop time in B06 position. EDF performed field examinations and some laboratory experiments to answer to this question. Two guide tubes were extracted from various cores. They were chosen due to their different positions within the core and the different nature of their counter bodies (different control rods surface treatment). Their continuous part were sliced to reduce their activity. Their dimensions were measured and compared to the nominal dimensions. Wear was evidenced with a low level. It is mainly concentrated around the notch. Some distinctions could be made depending on the guiding tube examined. Metallographic examinations were performed using SEM. The wear patterns of the guiding tubes appear similar from those of the control rods, which means that similar wear mechanisms must be involved. A tentative explanation of the increase of the rod drop time in position B06 is proposed. A tentative explanation of the low increase of rod drop time is presented. It could result from the conjunction of a larger pressing force in B06 position than in other position of the core as well as the conformal contact observed. The conformal contact in itself could results from the larger pressing force and the use of hardened rods. The findings of these field examinations have comforted EDF strategy concerning B06 guide tubes: they are changed before their drop time reaches a critical value. (authors)

Guided-Wave Optical Biosensors

Science.gov (United States)

Passaro, Vittorio M. N.; Dell'Olio, Francesco; Casamassima, Biagio; De Leonardis, Francesco

2007-01-01

Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.

IAEA activities to prepare safety codes and guides for thermal neutron nuclear power plants

International Nuclear Information System (INIS)

Iansiti, E.

1977-01-01

In accordance with the programme presented to, and endorsed by, the eighteenth General Conference in September 1974, the IAEA is now developing a complete set of safety codes and guides that will represent recommendations for the safety of thermal neutron power plants. The safety codes outline the minimum requirements for achieving this safety, and the safety guides set forth the criteria, procedures and methods to implement the safety codes. The whole programme is directed towards the five areas of Governmental Organization, Siting, Design, Operation, and Quality Assurance. One Scientific Secretary from the Agency Secretariat is responsible for each of these areas and a Co-ordinator takes care of common problems. For the development of each of these documents a working group of a few world experts is first convened which prepare a preliminary draft. This draft is then reviewed by a larger, international Technical Review Committee (one for each of the five areas) and a subsequent review by the Senior Advisory Group - with representatives from 20 states - ensures that the document is well coordinated within the programme. At this stage, it is sent to Member States for comments. The Technical Review Committee concerned is reconvened to integrate these comments into the document, and, after a final review by the Senior Advisory Group, the document is ready for transmission to the Director General of the Agency for endorsement and publication. A preliminary to this procedure is the collation by the Secretariat of large amounts of information submitted by Member States so that the first draft is really based on a very complete knowledge of what is done in each area all over the world. This collation frequently reveals differences in approach which are not random but due, rather, to the local conditions and the types of reactors. These differences must be harmonized in the documents produced without detracting from the effectiveness of the code or guide. The whole

Welding. Student Learning Guide.

Science.gov (United States)

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains 30 modules for completing a course in welding. It is designed especially for use in secondary schools in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities keyed to resources, information sheets, student self-check…

Electromobility guide; Wegweiser Elektromobilitaet

Energy Technology Data Exchange (ETDEWEB)

Becks, Thomas; De Doncker, Rik; Karg, Ludwig; Rehtanz, Christian; Reinhardt, Andreas-Michael; Willums, Jan-Olaf [eds.

2010-07-01

Knowing about funded projects and their results helps to safeguard own innovation activities, promotes precompetition know-how transfer and makes it easier to use synergetic effects. This is where the new ''Electromobility Guide'' has a contribution to make. It gives the reader basic information on more than 150 national and international projects about electromobility. It names contact partners and gives corresponding details to make it easier to collect additional information. Our intention is for the Electromobility Guide to act as an incentive for sharing current, authentic, correct and reliable information about all electromobility projects in order to expand the joint data basis. Please help us in this respect and support electromobility in Germany with your knowledge. (orig.)

DOE assessment guide for safeguards and security

International Nuclear Information System (INIS)

Bennett, C.A.; Christorpherson, W.E.; Clark, R.J.; Martin, F.; Hodges, Jr.

1978-04-01

DOE operations are periodically assessed to assure that special nuclear material, restricted data, and other classified information and DOE facilities are executed toward continuing the effectiveness of the International Atomic Energy Agency safeguards. A guide to describe the philosophy and mechanisms through which these assessments are conducted is presented. The assessment program is concerned with all contractor, field office, and Headquarters activities which are designed to assure that safeguards and security objectives are reached by contractors at DOE facilities and operations. The guide takes into account the interlocking relationship between many of the elements of an effective safeguards and security program. Personnel clearance programs are a part of protecting classified information as well as nuclear materials. Barriers that prevent or limit access may contribute to preventing theft of government property as well as protecting against sabotage. Procedures for control and surveillance need to be integrated with both information systems and procedures for mass balance accounting. Wherever possible, assessment procedures have been designed to perform integrated inspection, evaluation, and follow-up for the safeguards and security program

Innovative presentations for dummies

CERN Document Server

Anthony, Ray

2014-01-01

Be the speaker they follow with breakthrough innovative presentations Innovative Presentations For Dummies is a practical guide to engaging your audience with superior, creative, and ultra-compelling presentations. Using clear language and a concise style, this book goes way beyond PowerPoint to enable you to reimagine, reinvent, and remake your presentations. Learn how to stimulate, capture, and hold your audience in the palm of your hand with sound, sight, and touch, and get up to speed on the latest presentation design methods that make you a speaker who gets audiences committed and acting

Wetlands Are Wonderlands. Leader/Teacher Guide and Member/Youth Guide. 4-H Marine Education Series-1.

Science.gov (United States)

Meenen, Kimberly, Ed.; Goettel, Robin G., Ed.

This guide, for a 4-H wetlands project, is designed for sixth to eighth grade youth and their leaders interested in learning and doing aquatic science activities that can help the environment. The project provides basic wetland information with one or more activities for each of six sections: (1) What is a wetland?; (2) value of wetlands; (3)…

Measuring Physical Activity Intensity

Medline Plus

Full Text Available ... Needs for Pregnant or Postpartum Women Physical Activity & Health Adding Physical Activity to Your Life Activities for ... Guide Visual Guide Worksite Physical Activity Steps to Wellness Walkability Audit Tool Sample Audit Glossary Selected References ...

Measuring Physical Activity Intensity

Medline Plus

Full Text Available ... Physical Activity Data, Trends and Maps Surveillance Systems Resources & Publications Reports Adults Need More Physical Activity MMWR ... Active: Connecting Routes + Destinations Real-World Examples Implementation Resource Guide Visual Guide Worksite Physical Activity Steps to ...

Past, present and future of the nuclear activities in Argentina

International Nuclear Information System (INIS)

Cirimelo, Roberto O.

2001-01-01

A short history is given of the activities of the National Atomic Energy Commission. The present program in the field of the fuel cycle, material sciences, waste management, nuclear reactors, radioisotope production, radiation and radioisotope applications, research and development and education and training is described. The objectives and activities of the companies related to the National Atomic Energy Commission are also outlined

Developing a CANDU industry maintenance guide. A 'community of practice' compendium

International Nuclear Information System (INIS)

Von Hatten, P.; Hoye, D.S.

2011-01-01

The CANDU Owners Group (COG) has initiated a joint utility project to create an Industry Maintenance Guide. The primary goal of the guide is to provide a structured template of activities to implement the maintenance program, based on industry best practices, and with consideration for new regulatory requirements identified in the Canadian Nuclear Safety Commission document S210. The guide will be prepared with a macro view of the maintenance program, which includes core maintenance activities as well as supporting activities and programs in Engineering, Supply Chain and Work Management. Currently there is no such document that solidly links all the requirements to develop, support and execute a maintenance program. Some elements are captured in various industry documents such as INPO documents AP928, Work Management, AP913, Equipment Reliability and AP908, Materials and Services. The guide will not replicate these good practices, but will focus on how they are linked and interrelate to create an optimum program. It is expected that utilities will be able to utilize the guide to take the next incremental step in performance based on cross functional alignment and efficiency.

Electron wind in strong wave guide fields

Science.gov (United States)

Krienen, F.

1985-03-01

The X-ray activity observed near highly powered waveguide structures is usually caused by local electric discharges originating from discontinuities such as couplers, tuners or bends. In traveling waves electrons move in the direction of the power flow. Seed electrons can multipactor in a traveling wave, the moving charge pattern is different from the multipactor in a resonant structure and is self-extinguishing. The charge density in the wave guide will modify impedance and propagation constant of the wave guide. The radiation level inside the output wave guide of the SLAC, 50 MW, S-band, klystron is estimated. Possible contributions of radiation to window failure are discussed.

Evaluation of guided imagery as treatment for recurrent abdominal pain in children: a randomized controlled trial

Directory of Open Access Journals (Sweden)

Shapiro Daniel E

2006-11-01

Full Text Available Abstract Background Because of the paucity of effective evidence-based therapies for children with recurrent abdominal pain, we evaluated the therapeutic effect of guided imagery, a well-studied self-regulation technique. Methods 22 children, aged 5 – 18 years, were randomized to learn either breathing exercises alone or guided imagery with progressive muscle relaxation. Both groups had 4-weekly sessions with a therapist. Children reported the numbers of days with pain, the pain intensity, and missed activities due to abdominal pain using a daily pain diary collected at baseline and during the intervention. Monthly phone calls to the children reported the number of days with pain and the number of days of missed activities experienced during the month of and month following the intervention. Children with ≤ 4 days of pain/month and no missed activities due to pain were defined as being healed. Depression, anxiety, and somatization were measured in both children and parents at baseline. Results At baseline the children who received guided imagery had more days of pain during the preceding month (23 vs. 14 days, P = 0.04. There were no differences in the intensity of painful episodes or any baseline psychological factors between the two groups. Children who learned guided imagery with progressive muscle relaxation had significantly greater decrease in the number of days with pain than those learning breathing exercises alone after one (67% vs. 21%, P = 0.05, and two (82% vs. 45%, P Conclusion The therapeutic efficacy of guided imagery with progressive muscle relaxation found in this study is consistent with our present understanding of the pathophysiology of recurrent abdominal pain in children. Although unfamiliar to many pediatricians, guided imagery is a simple, noninvasive therapy with potential benefit for treating children with RAP.

Executive skills and reading comprehension a guide for educators

CERN Document Server

Cartwright, Kelly B

2015-01-01

How do K-12 students become self-regulated learners who actively deploy comprehension strategies to make meaning from texts? This cutting-edge guide is the first book to highlight the importance of executive skills for improving reading comprehension. Chapters review the research base for particular executive functions--such as planning, organization, cognitive flexibility, and impulse control--and present practical skills-building strategies for the classroom. Detailed examples show what each skill looks like in real readers, and sidebars draw explicit connections to the Common Core State Sta

Preparing Soups. Learning Activity Pack and Instructor's Guide 5.10b. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with preparing and serving soups. Illustrated information sheets and learning activities are provided in these areas: thin soups, thick soups, convenience soups,…

Yeast Breads. Learning Activity Pack and Instructor's Guide 5.15a. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with yeast breads and their ingredients. Illustrated information sheets and learning activities are provided in these areas: yeast breads and their ingredients,…

MR image reconstruction via guided filter.

Science.gov (United States)

Huang, Heyan; Yang, Hang; Wang, Kang

2018-04-01

Magnetic resonance imaging (MRI) reconstruction from the smallest possible set of Fourier samples has been a difficult problem in medical imaging field. In our paper, we present a new approach based on a guided filter for efficient MRI recovery algorithm. The guided filter is an edge-preserving smoothing operator and has better behaviors near edges than the bilateral filter. Our reconstruction method is consist of two steps. First, we propose two cost functions which could be computed efficiently and thus obtain two different images. Second, the guided filter is used with these two obtained images for efficient edge-preserving filtering, and one image is used as the guidance image, the other one is used as a filtered image in the guided filter. In our reconstruction algorithm, we can obtain more details by introducing guided filter. We compare our reconstruction algorithm with some competitive MRI reconstruction techniques in terms of PSNR and visual quality. Simulation results are given to show the performance of our new method.

The Inclusive Classroom. Professional's Guide.

Science.gov (United States)

Grenot-Scheyer, Marquita; And Others

Inclusive education reflects the changing culture of contemporary schools with emphasis on active learning, authentic assessment practices, applied curriculum, multi-level instructional approaches, and increased attention to diverse student needs and individualization. This guide is intended to help teachers implement inclusive educational…

Isolation of active constituents from cherry laurel (Laurocerasus officinalis Roem.) leaves through bioassay-guided procedures.

Science.gov (United States)

Akkol, Esra Küpeli; Kırmızıbekmez, Hasan; Küçükboyacı, Nurgün; Gören, Ahmet C; Yesilada, Erdem

2012-01-31

The fresh leaves of Laurocerasus officinalis Roem. (Rosaceae) are externally used against pain and feverish symptoms in Turkish folk medicine. Effects of the extracts, fractions and isolated compounds from the leaves of L. officinalis were investigated using in vivo models of inflammation and pain in mice. The crude ethanolic extract from the leaves of plant was sequentially fractionated into five subextracts; explicitly, n-hexane, chloroform, ethyl acetate (EtOAc), n-butanol, and remaining water extracts. Further studies were carried out on the most active EtOAc subextract was further subjected to fractionation through column chromatography. For the anti-inflammatory activity, carrageenan-induced hind paw edema and acetic acid-induced increase in capillary permeability models, and for the antinociceptive activity p-benzoquinone-induced writhing test in mice were employed. Ethanolic extract of the leaves was shown to possess significant inhibitory activity in the assay methods without inducing any gastric damage. Through bioassay-guided fractionation and isolation procedures three phenolic compounds, 2-O-β-D-glucopyranosyl-2-hydroxyphenyl-acetic acid (1), kaempferol-3-O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranoside (2) and (+)-catechin (3) were isolated from the active fraction and their structures were elucidated by spectral techniques (1D and 2D NMR, ESIMS). The experimental data verified that Laurocerasus officinalis leaves displayed remarkable anti-inflammatory and antinociceptive activity. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Short RNA guides cleavage by eukaryotic RNase III.

Directory of Open Access Journals (Sweden)

Bruno Lamontagne

Full Text Available In eukaryotes, short RNAs guide a variety of enzymatic activities that range from RNA editing to translation repression. It is hypothesized that pre-existing proteins evolved to bind and use guide RNA during evolution. However, the capacity of modern proteins to adopt new RNA guides has never been demonstrated. Here we show that Rnt1p, the yeast orthologue of the bacterial dsRNA-specific RNase III, can bind short RNA transcripts and use them as guides for sequence-specific cleavage. Target cleavage occurred at a constant distance from the Rnt1p binding site, leaving the guide RNA intact for subsequent cleavage. Our results indicate that RNase III may trigger sequence-specific RNA degradation independent of the RNAi machinery, and they open the road for a new generation of precise RNA silencing tools that do not trigger a dsRNA-mediated immune response.

A legislator`s guide to municipal solid waste management

Energy Technology Data Exchange (ETDEWEB)

Starkey, D; Hill, K

1996-08-01

The purpose of this guide is to allow individual state legislators to gain a better understanding of municipal solid waste (MSW) management issues in general, and examine the applicability of these concerns to their state. This guide incorporates a discussion of MSW management issues and a comprehensive overview of the components of an integrated solid waste management system. Major MSW topics discussed include current management issues affecting states, federal activities, and state laws and local activities. Solid waste characteristics and management approaches are also detailed.

Asymmetric Aldol Additions: A Guided-Inquiry Laboratory Activity on Catalysis

Science.gov (United States)

King, Jorge H. Torres; Wang, Hong; Yezierski, Ellen J.

2018-01-01

Despite the importance of asymmetric catalysis in both the pharmaceutical and commodity chemicals industries, asymmetric catalysis is under-represented in undergraduate chemistry laboratory curricula. A novel guided-inquiry experiment based on the asymmetric aldol addition was developed. Students conduct lab work to compare the effectiveness of…

Predisposal management of low and intermediate level radioactive waste. Safety guide

International Nuclear Information System (INIS)

2003-01-01

Radioactive waste is generated in the generation of electricity in nuclear power reactors and in the use of radioactive material in industry, research and medicine. The importance of the safe management of radioactive waste for the protection of human health and the environment has long been recognized. The principles and requirements that govern the safety of the management of radioactive waste are presented in 'The Principles of Radioactive Waste Management', 'Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety' and 'Predisposal Management of Radioactive Waste, Including Decommissioning'. The objective of this Safety Guide is to provide regulatory bodies and the operators that generate and manage radioactive waste with recommendations on how to meet the principles and requirements established in Refs for the predisposal management of LLW. This Safety Guide deals with the safety issues associated with the predisposal management of LLW from nuclear fuel cycle facilities, large research and development installations and radioisotope production facilities. This includes all steps and activities in the management of waste, from its initial generation to its final acceptance at a waste disposal facility or the removal of regulatory control. The predisposal management of radioactive waste includes decommissioning. The term 'decommissioning' encompasses both the process of decommissioning a facility and the management of the waste that results (prior to its disposal). Recommendations on the process of decommissioning are provided in Refs. Recommendations on the management of the waste resulting from decommissioning are included in this Safety Guide. Although the mining and milling of uranium and thorium ores is part of the nuclear fuel cycle, the management of the operational waste (e.g. waste rock, tailings and effluent treatment waste) from these activities is not within the scope of this Safety Guide. The LLW that is

Eliminating line of sight in elliptic guides using gravitational curving

International Nuclear Information System (INIS)

Kleno, Kaspar H.; Willendrup, Peter K.; Knudsen, Erik; Lefmann, Kim

2011-01-01

Eliminating fast neutrons (λ<0.5A) by removing direct line of sight between the source and the target sample is a well established technique. This can be done with little loss of transmission for a straight neutron guide by horizontal curving. With an elliptic guide shape, however, curving the guide would result in a breakdown of the geometrical focusing mechanism inherent to the elliptical shape, resulting in unwanted reflections and loss of transmission. We present a new and yet untried idea by curving a guide in such a way as to follow the ballistic curve of a neutron in the gravitational field, while still retaining the elliptic shape seen from the accelerated reference frame of the neutron. Analytical calculations and ray-tracing simulations show that this method is useful for cold neutrons at guide lengths in excess of 100 m. We will present some of the latest results for guide optimization relevant for instrument design at the ESS, in particular an off-backscattering spectrometer which utilizes the gravitational curving, for 6.66 A neutrons over a guide length of 300 m.

Predisposal management of high level radioactive waste. Safety guide

International Nuclear Information System (INIS)

2005-01-01

Radioactive waste is generated in the generation of electricity in nuclear power plants and in the use of radioactive material in industry, research and medicine. The importance of the safe management of radioactive waste for the protection of human health and the environment has long been recognized. The principles and requirements that govern the safety of the management of radioactive waste are presented in 'The Principles of Radioactive Waste Management', 'Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety' and 'Predisposal Management of Radioactive Waste, Including Decommissioning'. The objective of this Safety Guide is to provide regulatory bodies and the operators that generate and manage radioactive waste with recommendations on how to meet the principles and requirements established in Refs for the predisposal management of HLW. This Safety Guide applies to the predisposal management of HLW. For liquid HLW arising from the reprocessing of spent fuel the recommendations of this Safety Guide apply from when liquid waste from the first extraction process is collected for storage and subsequent processing. Recommendations and guidance on the storage of spent fuel, whether or not declared as waste, subsequent to its removal from the storage facility of a reactor are provided in Refs. For spent fuel declared as waste this Safety Guide applies to all activities subsequent to its removal from the storage facility of a reactor and prior to its disposal. Requirements pertaining to the transport of spent fuel, whether or not declared as waste, and of all forms of HLW are established. This Safety Guide provides recommendations on the safety aspects of managing HLW, including the planning, design, construction, commissioning, operation and decommissioning of equipment or facilities for the predisposal management of HLW. It addresses the following elements: (a) The characterization and processing (i.e. pretreatment

Guiding Warfare to Reach Sustainable Peace

DEFF Research Database (Denmark)

Vestenskov, David; Drewes, Line

The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition of develo......The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition...... of developing best practices in the education and implementation of IHL in capacity building of security forces....

A Variation of the Present Star Formation Activity of Spiral Galaxies

OpenAIRE

Tomita, Akihiko; Tomita, Yoshio; Saito, Mamoru

1996-01-01

The star formation rate in spiral galaxies is considered to be decreasing continuously with time in a time scale of $10^{9}$ yr. The present star formation activity, on the other hand, shows various degrees among galaxies. We make a new data set of 1681 nearby spiral galaxies from available databases and study the statistics of the present star formation activity. We analyze far-infrared and optical B-band surface brightnesses of the H II regions and the non-H II regions in M~31 and show that...

Influenza pandemic planning guide

Energy Technology Data Exchange (ETDEWEB)

NONE

2006-11-15

An influenza pandemic will have serious economic impacts on the natural gas industry due to absenteeism as well as downstream effects due to supply disruption.This guide was prepared to assist gas distribution companies in planning for an influenza epidemic. The guide aimed to minimize the risks that an influenza pandemic might pose to the health and safety of employees and the continuity of business operations. The guide discussed 5 critical aspects of emergency planning: (1) prevention and threat mitigation; (2) preparedness; (3) response; (4) business continuity; and (5) communication. The legal context of the emergency plans were discussed. The plans were also discussed to other essential infrastructure emergency response plans. Recommendations were presented for infection control, decentralization and access restriction. Outlines for pandemic response planning teams and training and exercise programs were provided. Issues related to alert, mobilization, and response procedures were also discussed. 10 refs., 3 tabs., 1 fig.

SAGE 2.1: SOLVENT ALTERNATIVES GUIDE: USER'S GUIDE

Science.gov (United States)

The guide provides instruction for using the SAGE (Solvent Alternatives GuidE) software system, version 2.1. SAGE recommends solvent replacements in cleaning and degreasing operations. It leads the user through a question-and-answer session. The user's responses allow the system ...

Castleman's disease, an unusual presentation

Directory of Open Access Journals (Sweden)

Shital Munde

2015-01-01

The present report describes a 30-year-old serving male who presented with pain abdomen and on and off episodes ofmelena, found to have peripancreatic lymphadenopathy on CECT abdomen. Ultrasound guided FN AC was done in private hospital revealed reactive lymphadenopathy. Excision biopsy was done in our institute and a diagnosis of Castleman's disease was made.

New polarizing guide for neutron wavelengths above 2.5 A

Energy Technology Data Exchange (ETDEWEB)

Krist, Th; Pappas, C; Teichert, A; Fehr, C; Clemens, D; Steichele, E; Mezei, F, E-mail: krist@helmholtz-berlin.de

2010-11-01

We present a new polarizing system built for the relocated wide angle Neutron Spin Echo instrument SPAN. The new instruments at the second Guide Hall of BENSC and the relocation of SPAN to this hall of BENSC required a new beam extraction system and a new polarizer for SPAN, which replaced the old beam splitter produced in 1994 with FeCo-Si supermirrors with m=2. The new polarizer uses Fe-Si supermirrors, which do not run the risk to become activated as the old FeCo-Si supermirrors and was designed to deliver a polarized beam for wavelengths above 2.5 A. The final polarizing cavity has a length of 9 m with a cross section of 60 mm x 100 mm. Si wafers coated on both sides with m=2.5 Fe-Si polarizing supermirrors are glued into the guide at an angle of 0.38{sup 0} to the walls. The guide was installed during the second half year of 2006 and the first tests in early 2007 revealed excellent polarization efficiency over the whole wavelength range of the spectrometer of 2.5 A to 9 A, amounting to above 95% at 4.5 A.

Mobile technologies in medical education: AMEE Guide No. 105.

Science.gov (United States)

Masters, Ken; Ellaway, Rachel H; Topps, David; Archibald, Douglas; Hogue, Rebecca J

2016-06-01

Mobile technologies (including handheld and wearable devices) have the potential to enhance learning activities from basic medical undergraduate education through residency and beyond. In order to use these technologies successfully, medical educators need to be aware of the underpinning socio-theoretical concepts that influence their usage, the pre-clinical and clinical educational environment in which the educational activities occur, and the practical possibilities and limitations of their usage. This Guide builds upon the previous AMEE Guide to e-Learning in medical education by providing medical teachers with conceptual frameworks and practical examples of using mobile technologies in medical education. The goal is to help medical teachers to use these concepts and technologies at all levels of medical education to improve the education of medical and healthcare personnel, and ultimately contribute to improved patient healthcare. This Guide begins by reviewing some of the technological changes that have occurred in recent years, and then examines the theoretical basis (both social and educational) for understanding mobile technology usage. From there, the Guide progresses through a hierarchy of institutional, teacher and learner needs, identifying issues, problems and solutions for the effective use of mobile technology in medical education. This Guide ends with a brief look to the future.

Present and future activities of TRIGA RC-1 Reactor

International Nuclear Information System (INIS)

Festinesi, A.

1986-01-01

A summary of reactor activities is presented and discussed. The RC-1 reactor is used by ENEA's laboratories, research institutes and national industries for different aims: research, analysis materials behaviour under neutron flux, etc. To satisfy the requests increase it is important to signalize: - the realization of a new radiochemical laboratory for radioisotopes production, to be used in a medical and/or diagnostic field in general; - the realization of a tritium handling laboratory, to study tritium solubility, release and diffusion in different material (particularly in ceramic breeder as lithium aluminate) to support Italian programs on fusion technology; - a research activity on the reactors computerized control by a console of advanced conception. The aim of this activity is the development of an ergonomic control room that could be a reference point for the planning of the power reactor control rooms

North Dakota Wetlands Discovery Guide. Photocopy Booklet.

Science.gov (United States)

Dietz, Nancy J., Ed.; And Others

This booklet contains games and activities that can be photocopied for classroom use. Activities include Wetland Terminology, Putting on the Map, Erosional Forces, Water in...Water out, Who Lives Here?, Wetlands in Disguise, Dichotomous Plant Game, Algae Survey, Conducting an Algal Survey, Water Quality Indicators Guide, Farming Wetlands, Wetlands…

Charged particle activation analysis at RIKEN. Past, present and future

International Nuclear Information System (INIS)

Nozaki, T.

2008-01-01

From 1960s to 1980s many groups in the world actively studied and utilized charged particle activation analysis (CPAA) mainly for absolute determination of B, C, N, and O in high-purity substances, particularly semiconductor materials. Here, after a short historical note on CPAA, works of the author's group mainly at RIKEN are outlined and then his opinion is shown about how to anticipate on the present shrinking of CPAA. (author)

Computerized Italian criticality guide, description and validation

International Nuclear Information System (INIS)

Carotenuto, M.; Landeyro, P.A.

1988-10-01

Our group is developing an 'expert system' for collecting engineering know-how on back-end nuclear plant design. An expert system is the most suitable software tool for our problem. During the analysis, the design process was divided into different branches. At each branch of the design process the Expert System relates a computerized design procedure. Any design procedure is composed of a set of design methods, together with their condition of application and reliability limits. In the framework of this expert system, the nuclear criticality safety analysis procedure was developed, in the form of a computerized criticality guide, attempting to reproduce the designer's normal 'reasoning' process. The criticality guide is composed of two parts: A computerized text, including theory, a description of the accidents occurred in the past and a description of the italian design experience; An interactive computer aided calculation module, containing a graphical facility for critical parameter curves. In the present report are presented the criticality guide (computerized Italian Criticality Guide) and its validation test. (author)

Computerized Italian criticality guide, description and validation

Energy Technology Data Exchange (ETDEWEB)

Carotenuto, M; Landeyro, P A [ENEA - Dipartimento Ciclo del Combustibile, Centro Ricerche Energia, Casaccia (Italy)

1988-10-15

Our group is developing an 'expert system' for collecting engineering know-how on back-end nuclear plant design. An expert system is the most suitable software tool for our problem. During the analysis, the design process was divided into different branches. At each branch of the design process the Expert System relates a computerized design procedure. Any design procedure is composed of a set of design methods, together with their condition of application and reliability limits. In the framework of this expert system, the nuclear criticality safety analysis procedure was developed, in the form of a computerized criticality guide, attempting to reproduce the designer's normal 'reasoning' process. The criticality guide is composed of two parts: A computerized text, including theory, a description of the accidents occurred in the past and a description of the italian design experience; An interactive computer aided calculation module, containing a graphical facility for critical parameter curves. In the present report are presented the criticality guide (computerized Italian Criticality Guide) and its validation test. (author)

Newly-formed emotional memories guide selective attention processes: Evidence from event-related potentials

OpenAIRE

Harald T. Schupp; Ursula Kirmse; Ralf Schmälzle; Tobias Flaisch; Britta Renner

2016-01-01

Emotional cues can guide selective attention processes. However, emotional stimuli can both activate long-term memory representations reflecting general world knowledge and engage newly formed memory representations representing specific knowledge from the immediate past. Here, the self-completion feature of associative memory was utilized to assess the regulation of attention processes by newly-formed emotional memory. First, new memory representations were formed by presenting pictures depi...

DOE interpretations Guide to OSH standards. Update to the Guide

Energy Technology Data Exchange (ETDEWEB)

1994-03-31

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued it`s support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal in letter written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

DOE interpretations Guide to OSH standards. Update to the Guide

Energy Technology Data Exchange (ETDEWEB)

1994-03-31

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

DOE interpretations Guide to OSH standards. Update to the Guide

Energy Technology Data Exchange (ETDEWEB)

1994-03-31

Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

Safety design guides for fire protection for CANDU 9

International Nuclear Information System (INIS)

Lee, Duk Su; Chang, Woo Hyun; Lee, Nam Young; A. C. D. Wright

1996-03-01

This safety design guide establishes design requirements to ensure the radiological risk to the public due to fire is acceptable and operating personnel are adequately protected from the hazards of fires. This safety design guide also specifies the safety criteria for fire protection to be applied to mitigate fires and recommends the fire protection program to be established to initiate, coordinate and document the design activities associated with fire protection. The requirements for fire protection outlined in this safety design guide shall be satisfied in the design stage and the change status of the regulatory requirements, code and standards should be traced and incorporated into this safety design guide accordingly. 1 fig., (Author) .new

Forsmark site investigation. Bedrock geology - overview and excursion guide

Energy Technology Data Exchange (ETDEWEB)

Stephens, Michael B. (Geological Survey of Sweden, Uppsala (Sweden))

2010-09-15

Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

Oskarshamn site investigation. Bedrock geology - overview and excursion guide

Energy Technology Data Exchange (ETDEWEB)

Wahlgren, Carl-Henric (Geological Survey of Sweden, Uppsala (Sweden))

2010-09-15

Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

Oskarshamn site investigation. Bedrock geology - overview and excursion guide

International Nuclear Information System (INIS)

Wahlgren, Carl-Henric

2010-09-01

Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark and Laxemar-Simpevarp (this guide) areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at eight representative outcrops or outcrop areas at the ground surface in the site investigation area at Laxemar-Simpevarp and at one locality north of this area, i.e. at a total of nine localities

Forsmark site investigation. Bedrock geology - overview and excursion guide

International Nuclear Information System (INIS)

Stephens, Michael B.

2010-09-01

Bearing in mind the significance of the bedrock data from the ground surface for the geological 3D modelling work, SKB decided to present excursion guides that serve in the demonstration of the bedrock geology at the ground surface in both the Forsmark (this guide) and Laxemar-Simpevarp areas. An excursion guide is also available for the Olkiluoto area in south-western Finland, which has been selected for the construction of a repository for the disposal of highly radioactive, spent nuclear fuel in Finland. The current excursion guide presents the bedrock geology and describes in detail the character of the bedrock at ten representative outcrops or outcrop areas at the ground surface in the site investigation area at Forsmark. All localities are located within or immediately adjacent to the proposed repository volume selected by SKB

Bioactivity-guided fractionation identifies amygdalin as a potent neurotrophic agent from herbal medicine Semen Persicae extract.

Science.gov (United States)

Yang, Chuanbin; Zhao, Jia; Cheng, Yuanyuan; Li, Xuechen; Rong, Jianhui

2014-01-01

Herbal medicine Semen Persicae is widely used to treat blood stasis in Chinese medicine and other oriental folk medicines. Although little is known about the effects of Semen Persicae and its active compounds on neuron differentiation, our pilot study showed that Semen Persicae extract promoted neurite outgrowth in rat dopaminergic PC12 cells. In the present study, we developed a bioactivity-guided fractionation procedure for the characterization of the neurotrophic activity of Semen Persicae extract. The resultant fractions were assayed for neurite outgrowth in PC12 cells based on microscopic assessment. Through liquid-liquid extraction and reverse phase HPLC separation, a botanical glycoside amygdalin was isolated as the active compound responsible for the neurotrophic activity of Semen Persicae extract. Moreover, we found that amygdalin rapidly induced the activation of extracellular-signal-regulated kinase 1/2 (ERK1/2). A specific ERK1/2 inhibitor PD98059 attenuated the stimulatory effect of amygdalin on neurite outgrowth. Taken together, amygdalin was identified as a potent neurotrophic agent from Semen Persicae extract through a bioactivity-guided fractional procedure. The neurotrophic activity of amygdalin may be mediated by the activation of ERK1/2 pathway.

Bioactivity-Guided Fractionation Identifies Amygdalin as a Potent Neurotrophic Agent from Herbal Medicine Semen Persicae Extract

Directory of Open Access Journals (Sweden)

Chuanbin Yang

2014-01-01

Full Text Available Herbal medicine Semen Persicae is widely used to treat blood stasis in Chinese medicine and other oriental folk medicines. Although little is known about the effects of Semen Persicae and its active compounds on neuron differentiation, our pilot study showed that Semen Persicae extract promoted neurite outgrowth in rat dopaminergic PC12 cells. In the present study, we developed a bioactivity-guided fractionation procedure for the characterization of the neurotrophic activity of Semen Persicae extract. The resultant fractions were assayed for neurite outgrowth in PC12 cells based on microscopic assessment. Through liquid-liquid extraction and reverse phase HPLC separation, a botanical glycoside amygdalin was isolated as the active compound responsible for the neurotrophic activity of Semen Persicae extract. Moreover, we found that amygdalin rapidly induced the activation of extracellular-signal-regulated kinase 1/2 (ERK1/2. A specific ERK1/2 inhibitor PD98059 attenuated the stimulatory effect of amygdalin on neurite outgrowth. Taken together, amygdalin was identified as a potent neurotrophic agent from Semen Persicae extract through a bioactivity-guided fractional procedure. The neurotrophic activity of amygdalin may be mediated by the activation of ERK1/2 pathway.

A Rare Presentation of a Morel-Lavallee Lesion of the Lower Leg Successfully Treated With Ultrasound-Guided Aspiration.

Science.gov (United States)

Falconi, Audrey; Crellin, Holly; Tagawa, Chelsea

2017-07-21

A Morel-Lavallee lesion (MLL) is a relatively rare condition that is caused by a traumatic shearing force. This force leads to a closed degloving injury of the subcutaneous tissue and fascia that creates a potential space that can fill with lymph, blood, and necrotic fat. The MLLs are traditionally seen after high impact trauma and typically located at the greater trochanter and pelvis, although recent reports have found them to be located at the knee, thigh, and lower leg. The MLLs typically present as swelling at the site of injury, which can be difficult to differentiate from several other diagnoses. This case report discusses an MLL in the lower extremity that occurred during a rugby game. A lack of familiarity with MLLs often leads to delayed diagnosis and treatment. The diagnosis was eventually made with an magnetic resonance imaging, and the lesion was successfully treated with ultrasound-guided aspiration and compression. The athlete was able to return to play without recurrence of the lesion.

COLLABORATIVE GUIDE: A REEF MANAGER'S GUIDE TO ...

Science.gov (United States)

Innovative strategies to conserve the world's coral reefs are included in a new guide released today by NOAA, and the Australian Great Barrier Reef Marine Park Authority, with author contributions from a variety of international partners from government agencies, non-governmental organizations, and academic institutions. Referred to as A Reef Manager's Guide to Coral Bleaching, the guide will provide coral reef managers with the latest scientific information on the causes of coral bleaching and new management strategies for responding to this significant threat to coral reef ecosystems. Innovative strategies to conserve the world's coral reefs are included in a new guide released today by NOAA, and the Australian Great Barrier Reef Marine Park Authority, with author contributions from a variety of international partners from government agencies, non-governmental organizations, and academic institutions. Dr. Jordan West, of the National Center for Environmental Assessment, was a major contributor to the guide. Referred to as

Measuring Physical Activity Intensity

Medline Plus

Full Text Available ... Guidelines Fact Sheets & Infographics Social Media Tools Community Strategies BE Active: Connecting Routes + Destinations Real-World Examples Implementation Resource Guide Visual Guide Worksite Physical Activity Steps ...

Production and guide tube transmission of very cold neutrons from pulsed cold source

International Nuclear Information System (INIS)

Utsuro, Masahiko; Okumura, Kiyoshi

1982-01-01

The intensity and the energy spectra of Very Cold Neutrons (VCN) transmitted through a curved guide tube were measured by using the time-of-flight method of VCN. In the measurements, the curved guide tube having a characteristic neutron velocity of about 70 m/s is combined to a pulsed cold source of an electron linac in an internal target geometry. A space dependence of the VCN spectra was observed on the radial positions of a detector at the guide tube exit. A simple theoretical analysis on the transmission of VCN in the curved guide tube is also presented with taking into consideration about the effects of a finite size and a finite distance of the VCN-emitting source, and simple analytical formulas for the exit spectra of the guide tube are given. Comparisons between the experimental results and the theoretical calculations show good agreements, and the satisfactory performance of the present VCN guide tube assembly was ascertained. These results present also instructive features for understanding the structures and the space dependence of the exit spectra of a neutron guide tube. The VCN spectra at the guide tube exit can be divided into a few energy regions according to the transmission processes of VCN. Thus, the present study provides useful informations for the preparations of a VCN source with a curved guide tube. (author)

Animals Alive! An Ecological Guide to Animal Activities. Revised Edition.

Science.gov (United States)

Holley, Dennis

This guide is designed to help teachers develop an inquiry-oriented program for studying the animal kingdom in which live animals are collected locally, studied, observed, and then released completely unharmed back into their natural habitats. This book addresses such concerns of life science teachers as the environmental soundness of methods and…

Views of Ancient Egypt. Teacher's Guide. School Arts: Looking/Learning.

Science.gov (United States)

Downs, Linda; Brenner, Carla

This teaching guide discusses ancient Egyptian culture, the lithographs made by Napoleon's scientists in 1798-99 to study and record every aspect of Egypt, the world's subsequent fascination with Egypt, ancient Egyptian architecture, Egyptian writing, and archeologists' illustrations of Egypt. The guide suggests activities for elementary school,…

Charged particle activation analysis: present status and future perspectives

International Nuclear Information System (INIS)

Chowdhury, D.P.

2006-01-01

Charged particle activation analysis is a highly sensitive nuclear analytical technique for the determination of elements at trace and ultra trace levels. CPAA involves the irradiation of samples with high energy charged particles, both light ions and heavy ions, from an accelerator in the energy range of 10 to 100 MeV. CPAA has been developed and standardized for the determination of several elements at trace levels in various types of materials using high energy ion beams from VEC machine at Kolkata. A brief review on CPAA is presented here based on our present works and its applications in future. (author)

Stimulation of the substantia nigra influences the specification of memory-guided saccades

Science.gov (United States)

Mahamed, Safraaz; Garrison, Tiffany J.; Shires, Joel

2013-01-01

In the absence of sensory information, we rely on past experience or memories to guide our actions. Because previous experimental and clinical reports implicate basal ganglia nuclei in the generation of movement in the absence of sensory stimuli, we ask here whether one output nucleus of the basal ganglia, the substantia nigra pars reticulata (nigra), influences the specification of an eye movement in the absence of sensory information to guide the movement. We manipulated the level of activity of neurons in the nigra by introducing electrical stimulation to the nigra at different time intervals while monkeys made saccades to different locations in two conditions: one in which the target location remained visible and a second in which the target location appeared only briefly, requiring information stored in memory to specify the movement. Electrical manipulation of the nigra occurring during the delay period of the task, when information about the target was maintained in memory, altered the direction and the occurrence of subsequent saccades. Stimulation during other intervals of the memory task or during the delay period of the visually guided saccade task had less effect on eye movements. On stimulated trials, and only when the visual stimulus was absent, monkeys occasionally (∼20% of the time) failed to make saccades. When monkeys made saccades in the absence of a visual stimulus, stimulation of the nigra resulted in a rotation of the endpoints ipsilaterally (∼2°) and increased the reaction time of contralaterally directed saccades. When the visual stimulus was present, stimulation of the nigra resulted in no significant rotation and decreased the reaction time of contralaterally directed saccades slightly. Based on these measurements, stimulation during the delay period of the memory-guided saccade task influenced the metrics of saccades much more than did stimulation during the same period of the visually guided saccade task. Because these effects

Autologous US-guided PRP injection versus US-guided focal extracorporeal shock wave therapy for chronic lateral epicondylitis: A minimum of 2-year follow-up retrospective comparative study.

Science.gov (United States)

Alessio-Mazzola, Mattia; Repetto, Ilaria; Biti, Besmir; Trentini, Roberto; Formica, Matteo; Felli, Lamberto

2018-01-01

To compare the efficacy of two independent groups of patients treated with ultrasound (US)-guided extracorporeal shock wave (ESW) therapy and with US-guided injection of platelet-rich plasma (PRP) for chronic lateral epicondylitis (LE) with a minimum of 2-year follow-up. We retrospectively evaluated 63 patients treated for chronic LE (31 patients with autologous US-guided PRP injection and 32 patients with US-guided focal ESW therapy) from 2009 to 2014. All the patients were evaluated by means of Roles-Maudsley (RM) score, quick Disabilities of Arm, Shoulder, and Hand (QuickDASH) score, visual analogic scale (VAS) and patient-rated tennis elbow evaluation (PRTEE) to retrospectively assess the pain relief, level of activity, the self-reported function and subjective satisfaction at minimum of 2-year follow-up. Both US-guided autologous PRP injection and US-guided focal ESW administration proved effective in chronic LE with significant improvement in the QuickDASH, VAS, RM and PRTEE scores ( p 0.05). The mean time between treatment and symptom resolution was significantly shorter for the PRP treatment ( p = 0.0212); furthermore, the mean time to return to the normal activities was quicker for PRP group ( p = 0.0119). Both PRP injection and ESW therapy are feasible and safe options for the treatment of chronic LE with low risk of complications and with good long-term follow-up results. US-guided PRP injection has quick efficacy when compared with US-guided focal ESW therapy.

TNF-Induced Target Cell Killing by CTL Activated through Cross-Presentation

Directory of Open Access Journals (Sweden)

Dirk Wohlleber

2012-09-01

Full Text Available Viruses can escape cytotoxic T cell (CTL immunity by avoiding presentation of viral components via endogenous MHC class I antigen presentation in infected cells. Cross-priming of viral antigens circumvents such immune escape by allowing noninfected dendritic cells to activate virus-specific CTLs, but they remain ineffective against infected cells in which immune escape is functional. Here, we show that cross-presentation of antigen released from adenovirus-infected hepatocytes by liver sinusoidal endothelial cells stimulated cross-primed effector CTLs to release tumor necrosis factor (TNF, which killed virus-infected hepatocytes through caspase activation. TNF receptor signaling specifically eliminated infected hepatocytes that showed impaired anti-apoptotic defense. Thus, CTL immune surveillance against infection relies on two similarly important but distinct effector functions that are both MHC restricted, requiring either direct antigen recognition on target cells and canonical CTL effector function or cross-presentation and a noncanonical effector function mediated by TNF.

TNF-induced target cell killing by CTL activated through cross-presentation.

Science.gov (United States)

Wohlleber, Dirk; Kashkar, Hamid; Gärtner, Katja; Frings, Marianne K; Odenthal, Margarete; Hegenbarth, Silke; Börner, Carolin; Arnold, Bernd; Hämmerling, Günter; Nieswandt, Bernd; van Rooijen, Nico; Limmer, Andreas; Cederbrant, Karin; Heikenwalder, Mathias; Pasparakis, Manolis; Protzer, Ulrike; Dienes, Hans-Peter; Kurts, Christian; Krönke, Martin; Knolle, Percy A

2012-09-27

Viruses can escape cytotoxic T cell (CTL) immunity by avoiding presentation of viral components via endogenous MHC class I antigen presentation in infected cells. Cross-priming of viral antigens circumvents such immune escape by allowing noninfected dendritic cells to activate virus-specific CTLs, but they remain ineffective against infected cells in which immune escape is functional. Here, we show that cross-presentation of antigen released from adenovirus-infected hepatocytes by liver sinusoidal endothelial cells stimulated cross-primed effector CTLs to release tumor necrosis factor (TNF), which killed virus-infected hepatocytes through caspase activation. TNF receptor signaling specifically eliminated infected hepatocytes that showed impaired anti-apoptotic defense. Thus, CTL immune surveillance against infection relies on two similarly important but distinct effector functions that are both MHC restricted, requiring either direct antigen recognition on target cells and canonical CTL effector function or cross-presentation and a noncanonical effector function mediated by TNF. Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved.

Evaluation of the antiproliferative activity of the leaves from Arctium lappa by a bioassay-guided fractionation.

Science.gov (United States)

Machado, Fabio Bahls; Yamamoto, Rafael Eidi; Zanoli, Karine; Nocchi, Samara Requena; Novello, Cláudio Roberto; Schuquel, Ivânia Teresinha Albrecht; Sakuragui, Cássia Mônica; Luftmann, Heinrich; Ueda-Nakamura, Tânia; Nakamura, Celso Vataru; de Mello, João Carlos Palazzo

2012-02-14

Arctium lappa L. (Asteraceae) is used in folk medicine around the World, and shows several kinds of biological activity, particularly in vitro antitumor activity in different cell lines. This study evaluated the antiproliferative activity of the crude extract, semipurified fractions, and isolated compounds from the leaves of A. lappa, through bioassay-guided testing in Caco-2 cells. The crude extract was obtained with a 50% hydroethanolic extract and then partitioned with hexane, ethyl acetate, and n-butanol. The ethyl-acetate fraction (EAF) showed antiproliferative activity. This fraction was subjected to sequential column chromatography over silica gel to afford onopordopicrin (1), mixtures of 1 with dehydromelitensin-8-(4'-hydroxymethacrylate) (2), a mixture of 2 with dehydromelitensin (3), mixture of 1 with melitensin (4), dehydrovomifoliol (5), and loliolide (6). The compounds were identified by spectroscopic methods (NMR, MS) and comparison with literature data. This is the first description of compounds 2-5 from this species. The compounds tested in Caco-2 cells showed the following CC(50) (µg/mL) values: 1: 19.7 ± 3.4, 1 with 2: 24.6 ± 1.5, 2 with 3: 27 ± 11.7, 1 with 4: 42 ± 13.1, 6 30 ± 6.2; compound 5 showed no activity.

Evaluation of the Antiproliferative Activity of the Leaves from Arctium lappa by a Bioassay-Guided Fractionation

Directory of Open Access Journals (Sweden)

Celso Vataru Nakamura

2012-02-01

Full Text Available Arctium lappa L. (Asteraceae is used in folk medicine around the World, and shows several kinds of biological activity, particularly in vitro antitumor activity in different cell lines. This study evaluated the antiproliferative activity of the crude extract, semipurified fractions, and isolated compounds from the leaves of A. lappa, through bioassay-guided testing in Caco-2 cells. The crude extract was obtained with a 50% hydroethanolic extract and then partitioned with hexane, ethyl acetate, and n-butanol. The ethyl-acetate fraction (EAF showed antiproliferative activity. This fraction was subjected to sequential column chromatography over silica gel to afford onopordopicrin (1, mixtures of 1 with dehydromelitensin-8-(4'-hydroxymethacrylate (2, a mixture of 2 with dehydromelitensin (3, mixture of 1 with melitensin (4, dehydrovomifoliol (5, and loliolide (6. The compounds were identified by spectroscopic methods (NMR, MS and comparison with literature data. This is the first description of compounds 2–5 from this species. The compounds tested in Caco-2 cells showed the following CC50 (µg/mL values: 1: 19.7 ± 3.4, 1 with 2: 24.6 ± 1.5, 2 with 3: 27 ± 11.7, 1 with 4: 42 ± 13.1, 6 30 ± 6.2; compound 5 showed no activity.

Identification of antihyperuricemic peptides in the proteolytic digest of shark cartilage water extract using in vivo activity-guided fractionation.

Science.gov (United States)

Murota, Itsuki; Taguchi, Satoko; Sato, Nobuyuki; Park, Eun Young; Nakamura, Yasushi; Sato, Kenji

2014-03-19

A peptide that exerts antihyperuricemic activity after oral administration was identified from a microbial protease (alcalase) digest of the water extract of shark cartilage by in vivo activity-guided fractionation, using oxonate-induced hyperuricemic rats. Water extract of shark cartilage was first fractionated by preparative ampholine-free isoelectric focusing, followed by preparative reversed-phase liquid chromatography. The antihyperuricemic activity of the alcalse digests of the obtained fractions was evaluated using an animal model. Alcalase digests of the basic and hydrophobic fractions exerted antihyperuricemic activity. A total of 18 peptides were identified in the alcalase digest of the final active fraction. These peptides were chemically synthesized and evaluated for antihyperuricemic activity. Tyr-Leu-Asp-Asn-Tyr and Ser-Pro-Pro-Tyr-Trp-Pro-Tyr lowered the serum uric acid level via intravenous injection at 5 mg/kg of body weight. Furthermore, orally administered Tyr-Leu-Asp-Asn-Tyr showed antihyperuricemic activity. Therefore, these peptides are at least partially responsible for the antihyperuricemic activity of the alcalase digest of shark cartilage.

Records Management Handbook; Source Data Automation Equipment Guide.

Science.gov (United States)

National Archives and Records Service (GSA), Washington, DC. Office of Records Management.

A detailed guide to selecting appropriate source data automation equipment is presented. Source data automation equipment is used to prepare data for electronic data processing or computerized recordkeeping. The guide contains specifications, performance data cost, and pictures of the major types of machines used in source data automation.…

Active Learning Environment with Lenses in Geometric Optics

Science.gov (United States)

Tural, Güner

2015-01-01

Geometric optics is one of the difficult topics for students within physics discipline. Students learn better via student-centered active learning environments than the teacher-centered learning environments. So this study aimed to present a guide for middle school teachers to teach lenses in geometric optics via active learning environment…

Standard Guide for Preparing Waste Management Plans for Decommissioning Nuclear Facilities

CERN Document Server

American Society for Testing and Materials. Philadelphia

2010-01-01

1.1 This guide addresses the development of waste management plans for potential waste streams resulting from decommissioning activities at nuclear facilities, including identifying, categorizing, and handling the waste from generation to final disposal. 1.2 This guide is applicable to potential waste streams anticipated from decommissioning activities of nuclear facilities whose operations were governed by the Nuclear Regulatory Commission (NRC) or Agreement State license, under Department of Energy (DOE) Orders, or Department of Defense (DoD) regulations. 1.3 This guide provides a description of the key elements of waste management plans that if followed will successfully allow for the characterization, packaging, transportation, and off-site treatment or disposal, or both, of conventional, hazardous, and radioactive waste streams. 1.4 This guide does not address the on-site treatment, long term storage, or on-site disposal of these potential waste streams. 1.5 This standard does not purport to address ...

Nuclear safety guide: TID--7016, Revision 2

International Nuclear Information System (INIS)

Thomas, J.T.

1978-01-01

The Nuclear Safety Guide was first issued in 1956 as classified AEC report LA-2063 and was reprinted the next year, unclassified, as TID-7016. Revision 1, published in 1961, extended the scope and refined the guiding information. Revision 2 of the Guide differs significantly from its predecessor in that the latter was intentionally conservative in its recommendations. Firmly based on experimental evidence of criticality, the original Guide and the first revision were considered to be of most value to organizations whose activities with fissionable materials were not extensive and, secondarily, that it would serve as a point of departure for members of established nuclear safety teams experienced in the field. The advance of calculational capability has permitted validated calculations to extend and substitute for experimental data. The broadened data base has enabled better interpolation, extension, and understanding of available information, especially in areas previously addressed by undefined but adequate factors of safety. The content has been thereby enriched in qualitative guidance. The information inherently contains, and the user can recapture, the quantitative guidance characteristic of the former Guides by employing appropriate safety factors

Safe and successful endoscopic initial treatment and long-term eradication of gastric varices by endoscopic ultrasound-guided Histoacryl (N-butyl-2-cyanoacrylate) injection

OpenAIRE

Gubler, Christoph; Bauerfeind, Peter

2014-01-01

OBJECTIVE: Optimal endoscopic treatment of gastric varices is still not standardized nowadays. Actively bleeding varices may prohibit a successful endoscopic injection therapy of Histoacryl® (N-butyl-2-cyanoacrylate). Since 2006, we have treated gastric varices by standardized endoscopic ultrasound (EUS) guided Histoacryl injection therapy without severe adverse events. MATERIAL AND METHODS: We present a large single-center cohort over 7 years with a standardized EUS-guided sclerotherapy o...

Agriculture & the Environment. Teacher's Guide.

Science.gov (United States)

McMurry, Linda Maston

This teacher's guide offers background information that teachers can use to incorporate topics related to agriculture and the environment into the curriculum. Classroom activities to bring these topics alive for students in grades 6-9 are suggested. Chapters include: (1) Pesticides and Integrated Pest Management; (2) Food Safety; (3) Water…

Building Maintenance. Student Learning Guide.

Science.gov (United States)

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains one module for completing a course in building maintenance. It is designed especially for use in secondary schools in Palm Beach County, Florida. The module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities keyed to resources, information sheets, student…

DOE Collegiate Wind Competition (Presentation)

Energy Technology Data Exchange (ETDEWEB)

Jones, J.

2014-02-01

This presentation for the January Stakeholder Engagement and Outreach webinar outlines the expanded need for workers in the wind industry and provides an overview of the DOE Wind Competition (to be held in May 2014) and the guiding principles of the competition.

SALOME. User's guide

International Nuclear Information System (INIS)

Zastrow, K.D.

1994-01-01

A user's guide for a least squares fit analysis program is presented, which has been developed for VUV and visible plasma spectroscopy on the Extrap-T1 experiment. The program can be used for line and multiplet identification, multiplet intensity and line width measurements. Atomic data are used extensively to aid the interpretation of the spectra. 7 figs

Regulatory Control of Radiation Sources. Safety Guide

International Nuclear Information System (INIS)

2009-01-01

This Safety Guide is intended to assist States in implementing the requirements established in Safety Standards Series No. GS-R-1, Legal and Governmental Infrastructure for Nuclear, Radiation, Radioactive Waste and Transport Safety, for a national regulatory infrastructure to regulate any practice involving radiation sources in medicine, industry, research, agriculture and education. The Safety Guide provides advice on the legislative basis for establishing regulatory bodies, including the effective independence of the regulatory body. It also provides guidance on implementing the functions and activities of regulatory bodies: the development of regulations and guides on radiation safety; implementation of a system for notification and authorization; carrying out regulatory inspections; taking necessary enforcement actions; and investigating accidents and circumstances potentially giving rise to accidents. The various aspects relating to the regulatory control of consumer products are explained, including justification, optimization of exposure, safety assessment and authorization. Guidance is also provided on the organization and staffing of regulatory bodies. Contents: 1. Introduction; 2. Legal framework for a regulatory infrastructure; 3. Principal functions and activities of the regulatory body; 4. Regulatory control of the supply of consumer products; 5. Functions of the regulatory body shared with other governmental agencies; 6. Organization and staffing of the regulatory body; 7. Documentation of the functions and activities of the regulatory body; 8. Support services; 9. Quality management for the regulatory system.

Curriculum Guide in Sex Education for the TMR.

Science.gov (United States)

Steward, Kathy L.

Presented is a sex education curriculum guide for teachers of trainable retarded students ages 12 to 21 years. The guide is divided into six units: body parts, gender identification, and restroom signs; living things; reproduction; growth; adolescence, menstruation, and street language; and maturity (including sexual feelings and birth control).…

Vegetables. Learning Activity Pack and Instructor's Guide 5.14. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with the major types of vegetables, with the procedures for storing vegetables, and with the general rules and methods of vegetable cookery. Illustrated…

Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

NARCIS (Netherlands)

Swarts, Daan C.; Oost, van der John; Jinek, Martin

2017-01-01

The CRISPR-associated protein Cas12a (Cpf1), which has been repurposed for genome editing, possesses two distinct nuclease activities: endoribonuclease activity for processing its own guide RNAs and RNA-guided DNase activity for target DNA cleavage. To elucidate the molecular basis of both

Workflow patterns the definitive guide

CERN Document Server

Russell, Nick; ter Hofstede, Arthur H M

2016-01-01

The study of business processes has emerged as a highly effective approach to coordinating an organization's complex service- and knowledge-based activities. The growing field of business process management (BPM) focuses on methods and tools for designing, enacting, and analyzing business processes. This volume offers a definitive guide to the use of patterns, which synthesize the wide range of approaches to modeling business processes. It provides a unique and comprehensive introduction to the well-known workflow patterns collection -- recurrent, generic constructs describing common business process modeling and execution scenarios, presented in the form of problem-solution dialectics. The underlying principles of the patterns approach ensure that they are independent of any specific enabling technology, representational formalism, or modeling approach, and thus broadly applicable across the business process modeling and business process technology domains. The authors, drawing on extensive research done by...

The Potato People in "School Daze": Presented by Theatre Beyond Words. Cue Sheet for Students.

Science.gov (United States)

Briley, Rachel

This performance guide is designed for teachers to use with students before and after a performance of the Potato People in "School Daze." The guide, called a "Cuesheet," contains seven pages of reproducible activity sheets for use in class with activities and discussion questions on the following topics: (1) Meet the…

Active illumination based 3D surface reconstruction and registration for image guided medialization laryngoplasty

Science.gov (United States)

Jin, Ge; Lee, Sang-Joon; Hahn, James K.; Bielamowicz, Steven; Mittal, Rajat; Walsh, Raymond

2007-03-01

The medialization laryngoplasty is a surgical procedure to improve the voice function of the patient with vocal fold paresis and paralysis. An image guided system for the medialization laryngoplasty will help the surgeons to accurately place the implant and thus reduce the failure rates of the surgery. One of the fundamental challenges in image guided system is to accurately register the preoperative radiological data to the intraoperative anatomical structure of the patient. In this paper, we present a combined surface and fiducial based registration method to register the preoperative 3D CT data to the intraoperative surface of larynx. To accurately model the exposed surface area, a structured light based stereo vision technique is used for the surface reconstruction. We combined the gray code pattern and multi-line shifting to generate the intraoperative surface of the larynx. To register the point clouds from the intraoperative stage to the preoperative 3D CT data, a shape priori based ICP method is proposed to quickly register the two surfaces. The proposed approach is capable of tracking the fiducial markers and reconstructing the surface of larynx with no damage to the anatomical structure. We used off-the-shelf digital cameras, LCD projector and rapid 3D prototyper to develop our experimental system. The final RMS error in the registration is less than 1mm.

Regulatory compliance guide for DOT-7A type A packaging design

International Nuclear Information System (INIS)

Kelly, D.L.

1996-01-01

The purpose of this guide is to provide instruction for assuring that the regulatory design requirements for a DOT-7A Type A packaging are met. This guide also supports the testing and evaluation activities that are performed on new packaging designs by a DOE-approved test facility through the DOE's DOT-7A Test Program. This Guide was updated to incorporate regulatory changes implemented by HM-169A (49 CFR, 'Transportation')

Family-Directed Transition Planning Guide.

Science.gov (United States)

Colorado State Dept. of Education, Denver. Div. of Special Education Services.

This guide to family-directed transition planning is intended to help parents and students with disabilities take leading roles in the process of transition from school to post-school activities. First, a letter to families examines the challenge of change and the transition process. Section 2 examines regulations that affect transition planning,…

A practical guide to designing a poster for presentation.

Science.gov (United States)

Briggs, D J

Poster presentations are frequently used to disseminate research findings and clinical initiatives at conferences, and present module material for educational courses. However, many nurses lack confidence when it comes to designing posters. This article considers the skills required to design a poster. Aspects of good poster design are also discussed.

Standard guide for qualification of measurement methods by a laboratory within the nuclear industry

CERN Document Server

American Society for Testing and Materials. Philadelphia

2003-01-01

1.1 This guide provides guidance for selecting, validating, and qualifying measurement methods when qualification is required for a specific program. The recommended practices presented in this guide provide a major part of a quality assurance program for the laboratory data (see Fig. 1). Qualification helps to assure that the data produced will meet established requirements. 1.2 The activities intended to assure the quality of analytical laboratory measurement data are diagrammed in Fig. 1. Discussion and guidance related to some of these activities appear in the following sections: Section Selection of Measurement Methods 5 Validation of Measurement Methods 6 Qualification of Measurement Methods 7 Control 8 Personnel Qualification 9 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitati...

A surface-electrode quadrupole guide for electrons

Energy Technology Data Exchange (ETDEWEB)

Hoffrogge, Johannes Philipp

2012-12-19

This thesis reports on the design and first experimental realization of a surface-electrode quadrupole guide for free electrons. The guide is based on a miniaturized, planar electrode layout and is driven at microwave frequencies. It confines electrons in the near-field of the microwave excitation, where strong electric field gradients can be generated without resorting to resonating structures or exceptionally high drive powers. The use of chip-based electrode geometries allows the realization of versatile, microstructured potentials with the perspective of novel quantum experiments with guided electrons. I present the design, construction and operation of an experiment that demonstrates electron confinement in a planar quadrupole guide for the first time. To this end, electrons with kinetic energies from one to ten electron-volts are guided along a curved electrode geometry. The stability of electron guiding as a function of drive parameters and electron energy has been studied. A comparison with numerical particle tracking simulations yields good qualitative agreement and provides a deeper understanding of the electron dynamics in the guiding potential. Furthermore, this thesis gives a detailed description of the design of the surface-electrode layout. This includes the development of an optimized coupling structure to inject electrons into the guide with minimum transverse excitation. I also discuss the extension of the current setup to longitudinal guide dimensions that are comparable to or larger than the wavelength of the drive signal. This is possible with a modified electrode layout featuring elevated signal conductors. Electron guiding in the field of a planar, microfabricated electrode layout allows the generation of versatile and finely structured guiding potentials. One example would be the realization of junctions that split and recombine a guided electron beam. Furthermore, it should be possible to prepare electrons in low-lying quantum mechanical

A surface-electrode quadrupole guide for electrons

International Nuclear Information System (INIS)

Hoffrogge, Johannes Philipp

2012-01-01

This thesis reports on the design and first experimental realization of a surface-electrode quadrupole guide for free electrons. The guide is based on a miniaturized, planar electrode layout and is driven at microwave frequencies. It confines electrons in the near-field of the microwave excitation, where strong electric field gradients can be generated without resorting to resonating structures or exceptionally high drive powers. The use of chip-based electrode geometries allows the realization of versatile, microstructured potentials with the perspective of novel quantum experiments with guided electrons. I present the design, construction and operation of an experiment that demonstrates electron confinement in a planar quadrupole guide for the first time. To this end, electrons with kinetic energies from one to ten electron-volts are guided along a curved electrode geometry. The stability of electron guiding as a function of drive parameters and electron energy has been studied. A comparison with numerical particle tracking simulations yields good qualitative agreement and provides a deeper understanding of the electron dynamics in the guiding potential. Furthermore, this thesis gives a detailed description of the design of the surface-electrode layout. This includes the development of an optimized coupling structure to inject electrons into the guide with minimum transverse excitation. I also discuss the extension of the current setup to longitudinal guide dimensions that are comparable to or larger than the wavelength of the drive signal. This is possible with a modified electrode layout featuring elevated signal conductors. Electron guiding in the field of a planar, microfabricated electrode layout allows the generation of versatile and finely structured guiding potentials. One example would be the realization of junctions that split and recombine a guided electron beam. Furthermore, it should be possible to prepare electrons in low-lying quantum mechanical

Guide to treatment technology for contaminated soils

International Nuclear Information System (INIS)

Tran, H.; Aylward, R.

1992-01-01

This document is a guide for the screening of alternative treatment technologies for contaminated soils. The contents of this guide are organized into: 1. Introduction, II. Utilizing the table, III. Tables: Contamination Versus Technology, TV. Contaminant Waste Groups, and V. References. The four Contaminations Versus Technology tables are designed to identify the effectiveness and/or potential applicability of technologies to some or all compounds within specific waste groups. The tables also present limitations and special use considerations for the particular treatment technology. The phase of development of the technology is also included in the table. The phases are: Available, Innovative, and Emerging technologies. The technologies presented in this guide are organized according to the method of treatment. The four (4) treatment methods are Biological, Solidification/Stabilization, Thermal, and Chemical/Physical Treatment. There are several processing methods; some are well developed and proven, and others are in the development stage

How To Select an Event Management System: A Guide to Selecting the Most Effective Resource Management System for College Union and Student Activities Professionals.

Science.gov (United States)

Anderson, Scott; Raasch, Kevin

2002-01-01

Provides an evaluation template for student activities professionals charged with evaluating competitive event scheduling software. Guides staff in making an informed decision on whether to retain event management technology provided through an existing vendor or choose "best-of-breed" scheduling software. (EV)

Guided imagery targeting exercise, food cravings, and stress: a multi-modal randomized feasibility trial.

Science.gov (United States)

Giacobbi, Peter; Long, Dustin; Nolan, Richard; Shawley, Samantha; Johnson, Kelsey; Misra, Ranjita

2018-02-01

The purpose of this randomized wait-list controlled trial was to test the feasibility and preliminary efficacy of a guided imagery based multi-behavior intervention intended to address psychological stress, food cravings, and physical activity. Personalized guided imagery scripts were created and participants were instructed to practice guided imagery every day for 35 consecutive days. Of 48 women who enrolled, we report comparisons between 16 randomized to treatment with 19 who were wait-listed (overall M age  = 45.50; M bodymassindex  = 31.43). Study completers reported 89% compliance with practicing guided imagery during the intervention. A significant time-by-group interaction was observed with reductions in food cravings and increases in physical activity compared with wait-list controls. Telephone-based multi-behavior interventions that utilize guided imagery to address food cravings and exercise behavior appear to be acceptable for overweight and obese women. Future phone-based guided imagery research testing this skill to address multiple health behaviors is justified.

Guide for understanding and evaluation of safety culture

International Nuclear Information System (INIS)

2008-01-01

This report was the guide of understanding and evaluation of safety culture. Operator's activities for enhancement of safety culture in nuclear installations became an object of safety regulation in the management system. Evaluation of operator's activities (including top management's involvement) to prevent degradation of safety culture and organization climate in daily works needed understanding of safety culture and diversity of operator's activities. This guide was prepared to check indications of degradation of safety culture and organization climate in operator's activities in daily works and encourage operator's activities to enhance safety culture improvement and good practice. Comprehensive evaluation of operator's activities to prevent degradation of safety culture and organization climate would be performed from the standpoints of 14 safety culture elements such as top management commitment, clear plan and implementation of upper manager, measures to avoid wrong decision making, questioning attitude, reporting culture, good communications, accountability and openness, compliance, learning system, activities to prevent accidents or incidents beforehand, self-assessment or third party evaluation, work management, change management and attitudes/motivation. Element-wise examples and targets for evaluation were attached with evaluation check tables. (T. Tanaka)

Ultrasound-controlled neuronavigator-guided brain surgery.

Science.gov (United States)

Koivukangas, J; Louhisalmi, Y; Alakuijala, J; Oikarinen, J

1993-07-01

The development of a unique neurosurgical navigator is described and a preliminary series of seven cases of intracerebral lesions approached with the assistance of this neuronavigation system under ultrasound control is presented. The clinical series included five low-grade astrocytomas, one chronic intracerebral hematoma, and one porencephalic cyst. Management procedures included biopsy in all cases, drainage of the hematoma, and endoscopy and fenestration for the cyst. The features of the neuronavigation system are interactive reconstructions of preoperative computerized tomography and magnetic resonance imaging data, corresponding intraoperative ultrasound images, versatility of the interchangeable end-effector instruments, graphic presentation of instruments on the reconstructed images, and voice control of the system. The principle of a common axis in the reconstructed images served to align the navigational pointer, biopsy guide, endoscope guide, ultrasound transducer, and surgical microscope to the brain anatomy. Intraoperative ultrasound imaging helped to verify the accuracy of the neuronavigator and check the results of the procedures. The arm of the neuronavigation system served as a holder for instruments, such as the biopsy guide, endoscope guide, and ultrasound transducer, in addition to functioning as a navigational pointer. Also, the surgical microscope was aligned with the neuronavigator for inspection and biopsy of the hematoma capsule to rule out tumor etiology. Voice control freed the neurosurgeon from manual exercises during start-up and calibration of the system.

Measuring Physical Activity Intensity

Medline Plus

Full Text Available ... Strategies BE Active: Connecting Routes + Destinations Real-World Examples Implementation Resource Guide Visual Guide Worksite Physical Activity ... Implementation Maintaining Interest Needs Assessment Evaluating Success CDC’s Example ... Stairwell Appearance Motivational Signs Installing Music Other ...

Ornamental Horticulture Production Occupations. Curriculum Guide.

Science.gov (United States)

Reneau, Fred; And Others

This curriculum guide contains guidesheets for the ornamental horticulture production occupations. Each guidesheet provides a job-relevant task; performance objective, with task, performance standard, source of standard, and conditions for performance of task; enabling objectives; a list of resources; teaching activities; a criterion-referenced…

Implementation Guide: Leading School Change

Science.gov (United States)

Whitaker, Todd

2010-01-01

This two-part "Implementation Guide" will help to deepen your understanding and sharpen your ability to implement each of the strategies discussed in "Leading School Change: Nine Strategies to Bring Everybody on Board" (ED509821). Part One offers discussion questions and activities which focus on each of the nine strategies. They can be completed…

Nanoparticle-guided radiotherapy

DEFF Research Database (Denmark)

2012-01-01

The present invention relates to a method and nano-sized particles for image guided radiotherapy (IGRT) of a target tissue. More specifically, the invention relates to nano-sized particles comprising X-ray-imaging contrast agents in solid form with the ability to block x-rays, allowing for simult...... for simultaneous or integrated external beam radiotherapy and imaging, e.g., using computed tomography (CT)....

A Tourism e-Guide System Using Mobile Integration

Directory of Open Access Journals (Sweden)

Emad M. Abuelrub

2010-04-01

Full Text Available This paper presents a tourism e-guide system via mobile integration using offloading while enjoying mobility. A user can search for new mobile services available on the website to use either remotely on the server where the services resides, or locally after downloading them to his/her mobile device and work offline without a mobile connection. Jordan Tourism e-Guide System (JTeGS aims to help the user/tourist accessing the tourism information directly from his/her smart device, anytime and anywhere using offloading. JTeGS is a web-based electronic guide that provides the user with appropriate tourism information about Jordan and guides him/her to find the best places to party, eat out, and enjoy culture events. The system architecture and the main components of the proposed services were presented and discussed. The system has been prototyped and validated in a real-time mobile internet application scenario. The system also has been evaluated through simulations in mobile network environment. Both experimental and simulation results demonstrated the effectiveness and efficiency of the proposed system.

A field guide to digital color

CERN Document Server

Stone, Maureen

2013-01-01

Maureen Stone's field guide to digital color presents a survey of digital color with special emphasis on those fields important for computer graphics. The book provides the foundation for understanding color and its applications, discusses color media and color management and the use of color in computer graphics, including color design and selection. The book provides a guide for anyone who wants to understand and apply digital color. An annotated bibliography provides in-depth references for further study on each topic.

Image-guided recording system for spatial and temporal mapping of neuronal activities in brain slice.

Science.gov (United States)

Choi, Geonho; Lee, Jeonghyeon; Kim, Hyeongeun; Jang, Jaemyung; Im, Changkyun; Jeon, Nooli; Jung, Woonggyu

2018-03-01

In this study, we introduce the novel image-guided recording system (IGRS) for efficient interpretation of neuronal activities in the brain slice. IGRS is designed to combine microelectrode array (MEA) and optical coherence tomography at the customized upright microscope. It allows to record multi-site neuronal signals and image of the volumetric brain anatomy in a single body configuration. For convenient interconnection between a brain image and neuronal signals, we developed the automatic mapping protocol that enables us to project acquired neuronal signals on a brain image. To evaluate the performance of IGRS, hippocampal signals of the brain slice were monitored, and corresponding with two-dimensional neuronal maps were successfully reconstructed. Our results indicated that IGRS and mapping protocol can provide the intuitive information regarding long-term and multi-sites neuronal signals. In particular, the temporal and spatial mapping capability of neuronal signals would be a very promising tool to observe and analyze the massive neuronal activity and connectivity in MEA-based electrophysiological studies. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Networked innovations in guided tours

DEFF Research Database (Denmark)

Meged, Jane Widtfeldt; Zillinger, Malin

This presentation is about a case study being done on networked innovation that is taking place within the scene of free guided tours in Copenhagen. Data has been collected on interactions between actors within the network of peers. In this way, both the own organisation and the actual market...... is being continually developed. ICT plays a key role, just as well as the relationships between the individual actors. It has been shown that close relationships building on friendship and trust are beneficial for the process of innovation. The fast growth of the sector of free guided tours however poses...

Safety Information System Guide

International Nuclear Information System (INIS)

Bullock, M.G.

1977-03-01

This Guide provides guidelines for the design and evaluation of a working safety information system. For the relatively few safety professionals who have already adopted computer-based programs, this Guide may aid them in the evaluation of their present system. To those who intend to develop an information system, it will, hopefully, inspire new thinking and encourage steps towards systems safety management. For the line manager who is working where the action is, this Guide may provide insight on the importance of accident facts as a tool for moving ideas up the communication ladder where they will be heard and acted upon; where what he has to say will influence beneficial changes among those who plan and control his operations. In the design of a safety information system, it is suggested that the safety manager make friends with a computer expert or someone on the management team who has some feeling for, and understanding of, the art of information storage and retrieval as a new and better means for communication

Macrophage Activation Syndrome as Initial Presentation of Systemic Lupus Erythematosus

Directory of Open Access Journals (Sweden)

Say-Tin Yeap

2008-04-01

Full Text Available Macrophage activation syndrome (MAS is known to be a severe and potentially life-threatening complication of rheumatic disorder, especially systemic juvenile rheumatoid arthritis. It is very rare for MAS to be an initial presentation of systemic lupus erythematosus (SLE. Here, we report a 14-year-old girl in whom MAS developed as an initial presentation of SLE. With early diagnosis and administration of cyclosporine A, she had a fair outcome. Further testing showed positive anti-dsDNA about 8 months later.

Field Trip Guide to Serpentinite, Silica-Carbonate Alteration, and Related Hydrothermal Activity in the Clear Lake Region, California

Energy Technology Data Exchange (ETDEWEB)

Fraser Goff; George Guthrie

1999-06-01

This guide is designed to familiarize scientists with the geology, structure, alteration, and fluids typical of California serpentinites for purposes of carbon dioxide sequestration (Lackner et al., 1995). Goff et al. (1997) and Goff and Lackner (1998) describe the geology and geochemistry of some of the serpentinites from this area. Mechanisms of silica-carbonate alteration were outlined by Barnes et al. (1973). Donnelly-Nolan et al. (1993) most recently reviewed relations between regional hydrothermal alteration and Quarternary volcanic activity. Stanley et al. (1998) summarized geophysical characteristics of the region.

Bioassay-Guided Isolation of Cytotoxic Isocryptoporic Acids from Cryptoporus volvatus

Directory of Open Access Journals (Sweden)

Ling-Yun Zhou

2016-12-01

Full Text Available The present work constitutes a contribution to the phytochemical investigation of Cryptoporus volvatus aiming to search for effective cytotoxic constituents against tumor cell lines in vivo. Bioassay-guided separation of the ethylacetate extract of C. volvatus afforded four new isocryptoporic acid (ICA derivatives, ICA-B trimethyl ester (1, ICA-E (2, ICA-E pentamethyl ester (3, and ICA-G (4, together with nine known cryptoporic acids. These isocryptoporic acids are isomers of the cryptoporic acids with drimenol instead of albicanol as the terpenoid fragment; their structures were elucidated on the basis of spectroscopic evidences (UV, IR, HRMS, and NMR and comparison with literature values. All isolates show certain cytotoxic activities against five tumor cell lines. Among them, compound 4 showed an comparable activity to that of the positive control cis-platin, while other compounds exhibited weak cytotoxic activities.

Improving the Impact of Extension through the Use of Anticipation Guides

Science.gov (United States)

Smith, Rebecca C.; Lemley, Stephanie M.

2017-01-01

In this article, we present the anticipation guide as a tool for preparing Extension audiences to learn the main points of Extension materials. Anticipation guides improve learner comprehension by appealing to an individual's natural curiosity and helping the individual focus on key ideas. Anticipation guides can be used with all types of…

Aeronautics. An Educator's Guide with Activities in Science, Mathematics, and Technology Education: What Pilot, Astronaut, or Aeronautical Engineer didn't Start out with a Toy Glider?

Science.gov (United States)

Biggs, Pat (Editor); Huetter, Ted (Editor)

1998-01-01

Welcome to the exciting world of aeronautics. The term aeronautics originated in France, and was derived from the Greek words for "air" and "to sail." It is the study of flight and the operation of aircraft. This educator guide explains basic aeronautical concepts, provides a background in the history of aviation, and sets them within the context of the flight environment (atmosphere, airports, and navigation). The activities in this guide are designed to be uncomplicated and fun. They have been developed by NASA Aerospace Education Services Program specialists, who have successfully used them in countless workshops and student programs around the United States. The activities encourage students to explore the nature of flight, and experience some real-life applications of mathematics, science, and technology. The subject of flight has a wonderful power to inspire learning.

Commercial Foods and Culinary Arts. Student Learning Guides.

Science.gov (United States)

Ridge Vocational-Technical Center, Winter Haven, FL.

These 13 learning guides are self-instructional packets for 13 tasks identified as essential for performance on an entry-level job in commercial foods and culinary arts. Each guide is based on a terminal performance objective (task) and 1-4 enabling objectives. For each enabling objective, some or all of these materials may be presented: learning…

Tourists in space a practical guide

CERN Document Server

Seedhouse, Erik

2014-01-01

Forget Hawaii or the Mediterranean. Soon – very soon – you’ll be able to add a much more exotic stamp to your passport: space. How will you get there, what will the trip be like, and how much training will you need? All you need to know is right here in this guide. Tourists in Space: A Practical Guide supplies all the advice and information you need to make your spaceflight the most rewarding experience of your life. This definitive, real-world guide is packed with helpful facts and suggestions on everything from training, equipment, safety, and in-flight procedures to techniques for avoiding space motion sickness and bone demineralization. You’ll also find: • Advice on choosing your training agency • Techniques for minimizing the risk of space motion sickness • Information you need to prepare for your medical examination, training, and flight • Tips on activities near your training location And much more.

Nonreactor nuclear facilities: standards and criteria guide

International Nuclear Information System (INIS)

Brynda, W.J.; Junker, L.; Karol, R.C.; Lobner, P.R.; Goldman, L.A.

1981-09-01

This guide is a source document that identifies standards, codes, and guides that address the nuclear safety considerations pertinent to nuclear facilities as defined in DOE Order 5480.1, Chapter V, Safety of Nuclear Facilities. The guidance and criteria provided are directed toward areas of safety usually addressed in a Safety Analysis Report. The areas of safety include, but are not limited to, siting, principal design criteria and safety system design guidelines, radiation protection, accident analysis, and quality assurance. The guide is divided into two sections: general guidelines and appendices. Those guidelines that are broadly applicable to most nuclear facilities are presented in the general guidelines. These general guidelines may have limited applicability to subsurface facilities such as waste repositories. Guidelines specific to the various types or categories of nuclear facilities are presented in the appendices. These facility-specific appendices provide guidelines and identify standards and criteria that should be considered in addition to, or in lieu of, the general guidelines

Nonreactor nuclear facilities: Standards and criteria guide

International Nuclear Information System (INIS)

Brynda, W.J.; Scarlett, C.H.; Tanguay, G.E.; Lobner, P.R.

1986-09-01

This guide is a source document that identifies standards, codes, and guides that address the nuclear safety considerations pertinent to nuclear facilities as defined in DOE 5480.1A, Chapter V, ''Safety of Nuclear Facilities.'' The guidance and criteria provided is directed toward areas of safety usually addressed in a Safety Analysis Report. The areas of safety include, but are not limited to, siting, principal design criteria and safety system design guidelines, radiation protection, accident analysis, conduct of operations, and quality assurance. The guide is divided into two sections: general guidelines and appendices. Those guidelines that are broadly applicable to most nuclear facilities are presented in the general guidelines. Guidelines specific to the various types or categories of nuclear facilities are presented in the appendices. These facility-specific appendices provide guidelines and identify standards and criteria that should be considered in addition to, or in lieu of, the general guidelines. 25 figs., 62 tabs

Risk management guide

International Nuclear Information System (INIS)

Briscoe, G.J.

1977-06-01

Risk management requires an assessment or a knowledge of risk. This, in turn, requires identification of hazards (sources of risk) and a determination of risk (evaluation of the hazard degree). The hazard identification and risk analysis techniques presented in this Guide are, in general, based on the MORT concept that accidents result from unwanted energy flow in the absence of adequate controls and/or barriers. This Guide presents an analytical tree designed to prevent oversight of specific energy sources in risk identification. Hazard identification by field personnel is also discussed. Quantitative risk analysis is discussed in the following section. A method for summary of the risks for each energy classification is given. This method uses a graphical log-normal projection so that low probability events, which are not adequately represented in the experience data, are included in the risk assessment. This permits a more acceptable risk assessment since catastrophes are not ignored, even though the actual risk is only approximated. In addition, a few examples of risk analysis of specific hazards are given. Rudimentary probability and fault tree theory are used in these examples. Total risk assessment and resource allocation and safety performance trend analysis are discussed

Learner's Guide: Water Quality Monitoring. An Instructional Guide for the Two-Year Water Quality Monitoring Curriculum.

Science.gov (United States)

Glazer, Richard B.; And Others

This learner's guide is designed to meet the training needs for technicians involved in monitoring activities related to the Federal Water Pollution Act and the Safe Drinking Water Act. In addition it will assist technicians in learning how to perform process control laboratory procedures for drinking water and wastewater treatment plant…

Hospitality Services. Curriculum Guide [and] Student Activity Book [and] Reference Book.

Science.gov (United States)

Texas Tech Univ., Lubbock. Curriculum Center for Family and Consumer Sciences.

These three publications comprise a course that provides occupationally specific training designed to develop knowledge and skills for employment in the multifaceted hospitality services industry. The curriculum guide is the teacher component of the series. Contents include the Texas Essential Knowledge and Skills (TEKS); sample course outlines;…

Hospitality Occupations. Curriculum Guide.

Science.gov (United States)

California State Dept. of Education, Sacramento. Bureau of Homemaking Education.

This curriculum guide on the hospitality occupations was developed to help secondary and postsecondary home economics teachers prepare individuals for entry-level jobs in the hospitality industry. The content is in seven sections. The first section presents organizational charts of a medium-size hotel, food and beverage division, housekeeping and…

Guided Modern Endodontic Surgery: A Novel Approach for Guided Osteotomy and Root Resection.

Science.gov (United States)

Strbac, Georg D; Schnappauf, Albrecht; Giannis, Katharina; Moritz, Andreas; Ulm, Christian

2017-03-01

Continuous improvements in techniques, instruments, and materials have established modern endodontic microsurgery as a state-of-the-art treatment method. The purpose of this approach was to introduce a new surgical endodontic technique by using a three-dimensional printed template for guided osteotomy and root resection. A 38-year-old patient was diagnosed with periapical lesions of teeth #3 and #4 and extruded gutta-percha material. Three-dimensional radiographic and optical scan files were imported into surgical planning software designed for guided implant surgery. Within the adapted software program the periapical lesions and the extruded gutta-percha were visualized and marked. With the aid of virtually positioned surgical pins and piezoelectric instruments, the osteotomy size, the apical resection level, and the bevel angle were defined before treatment. Three-dimensional surgical templates for each tooth were designed within the software program for a guided treatment approach. This approach comprised the treatment of periapical lesions of teeth #3 and #4 with root-end fillings and the detection and complete removal of the extruded gutta-percha material without perforation of sinus membrane. There were no postoperative complications, and clinical and radiologic assessments verified complete healing of the teeth. The guided microsurgical endodontic treatment presented appears to be a viable technique that allows for predefined osteotomies and root resections. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

Introduction to Fish and Shellfish. Learning Activity Pack and Instructor's Guide 5.13a. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with fish and shellfish for restaurant use. Illustrated information sheets and learning activities are provided in these areas: buying and storing fish and…

Bioactivity-guided fractionation and analysis of compounds with anti-influenza virus activity from Gardenia jasminoides Ellis.

Science.gov (United States)

Yang, Quanjun; Wu, Bin; Shi, Yujing; Du, Xiaowei; Fan, Mingsong; Sun, Zhaolin; Cui, Xiaolan; Huang, Chenggang

2012-01-01

Bioassay-guided fractionation of extracts from Fructus Gardeniae led to analysis of its bioactive natural products. After infection by influenza virus strain A/FM/1/47-MA in vivo, antiviral activity of the extracts were investigated. The target fraction was orally administered to rats and blood was collected. High-performance liquid chromatography coupled with photo diode array detector and electrospray ion trap multiple-stage tandem mass spectrometry was applied to screen the compounds absorbed into the blood. A structural characterization based on the retention time, ultraviolet spectra, parent ions and fragmentation ions was performed. Thirteen compounds were confirmed or tentatively identified. This provides an accurate profile of the composition of bioactive compounds responsible for the anti-influenza properties.

Using PyMOL to Explore the Effects of ph on Noncovalent Interactions between Immunoglobulin G and Protein A: A Guided-Inquiry Biochemistry Activity

Science.gov (United States)

Roche Allred, Zahilyn D.; Tai, Heeyoung; Bretz, Stacey Lowery; Page, Richard C.

2017-01-01

Students' understandings of foundational concepts such as noncovalent interactions, pH and pK[subscript a] are crucial for success in undergraduate biochemistry courses. We developed a guided-inquiry activity to aid students in making connections between noncovalent interactions and pH/pK[subscript a]. Students explore these concepts by examining…

Agile practice guide

CERN Document Server

2017-01-01

Agile Practice Guide – First Edition has been developed as a resource to understand, evaluate, and use agile and hybrid agile approaches. This practice guide provides guidance on when, where, and how to apply agile approaches and provides practical tools for practitioners and organizations wanting to increase agility. This practice guide is aligned with other PMI standards, including A Guide to the Project Management Body of Knowledge (PMBOK® Guide) – Sixth Edition, and was developed as the result of collaboration between the Project Management Institute and the Agile Alliance.

Lasers. Technology Learning Activity. Teacher Edition. Technology Education Series.

Science.gov (United States)

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document contains the materials required for presenting an 8-day competency-based technology learning activity (TLA) designed to introduce students in grades 6-10 to advances and career opportunities in the field of laser technology. The guide uses a series of hands-on exploratory experiences into which activities to help students develop…

Educational activities of remote sensing archaeology (Conference Presentation)

Science.gov (United States)

Hadjimitsis, Diofantos G.; Agapiou, Athos; Lysandrou, Vasilki; Themistocleous, Kyriacos; Cuca, Branka; Nisantzi, Argyro; Lasaponara, Rosa; Masini, Nicola; Krauss, Thomas; Cerra, Daniele; Gessner, Ursula; Schreier, Gunter

2016-10-01

Remote sensing science is increasingly being used to support archaeological and cultural heritage research in various ways. Satellite sensors either passive or active are currently used in a systematic basis to detect buried archaeological remains and to systematic monitor tangible heritage. In addition, airborne and low altitude systems are being used for documentation purposes. Ground surveys using remote sensing tools such as spectroradiometers and ground penetrating radars can detect variations of vegetation and soil respectively, which are linked to the presence of underground archaeological features. Education activities and training of remote sensing archaeology to young people is characterized of highly importance. Specific remote sensing tools relevant for archaeological research can be developed including web tools, small libraries, interactive learning games etc. These tools can be then combined and aligned with archaeology and cultural heritage. This can be achieved by presenting historical and pre-historical records, excavated sites or even artifacts under a "remote sensing" approach. Using such non-form educational approach, the students can be involved, ask, read, and seek to learn more about remote sensing and of course to learn about history. The paper aims to present a modern didactical concept and some examples of practical implementation of remote sensing archaeology in secondary schools in Cyprus. The idea was built upon an ongoing project (ATHENA) focused on the sue of remote sensing for archaeological research in Cyprus. Through H2020 ATHENA project, the Remote Sensing Science and Geo-Environment Research Laboratory at the Cyprus University of Technology (CUT), with the support of the National Research Council of Italy (CNR) and the German Aerospace Centre (DLR) aims to enhance its performance in all these new technologies.

Downstream fish passage guide walls: A hydraulic scale model analysis

Science.gov (United States)

Mulligan, Kevin; Towler, Brett; Haro, Alexander J.; Ahlfeld, David P.

2018-01-01

Partial-depth guide walls are used to improve passage efficiency and reduce the delay of out-migrating anadromous fish species by guiding fish to a bypass route (i.e. weir, pipe, sluice gate) that circumvents the turbine intakes, where survival is usually lower. Evaluation and monitoring studies, however, indicate a high propensity for some fish to pass underneath, rather than along, the guide walls, compromising their effectiveness. In the present study we evaluated a range of guide wall structures to identify where/if the flow field shifts from sweeping (i.e. flow direction primarily along the wall and towards the bypass) to downward-dominant. Many migratory fish species, particularly juveniles, are known to drift with the flow and/or exhibit rheotactic behaviour during their migration. When these behaviours are present, fish follow the path of the flow field. Hence, maintaining a strong sweeping velocity in relation to the downward velocity along a guide wall is essential to successful fish guidance. Nine experiments were conducted to measure the three-dimensional velocity components upstream of a scale model guide wall set at a wide range of depths and angles to flow. Results demonstrated how each guide wall configuration affected the three-dimensional velocity components, and hence the downward and sweeping velocity, along the full length of the guide wall. In general, the velocities produced in the scale model were sweeping dominant near the water surface and either downward dominant or close to the transitional depth near the bottom of the guide wall. The primary exception to this shift from sweeping do downward flow was for the minimum guide wall angle tested in this study (15°). At 15° the flow pattern was fully sweeping dominant for every cross-section, indicating that a guide wall with a relatively small angle may be more likely to produce conditions favorable to efficient guidance. A critical next step is to evaluate the behaviour of migratory fish as

The Effectiveness of Guided Inquiry Learning for Comparison Topics

Science.gov (United States)

Asnidar; Khabibah, S.; Sulaiman, R.

2018-01-01

This research aims at producing a good quality learning device using guided inquiry for comparison topics and describing the effectiveness of guided inquiry learning for comparison topics. This research is a developmental research using 4-D model. The result is learning device consisting of lesson plan, student’s worksheet, and achievement test. The subjects of the study were class VII students, each of which has 46 students. Based on the result in the experimental class, the learning device using guided inquiry for comparison topics has good quality. The learning device has met the valid, practical, and effective aspects. The result, especially in the implementation class, showed that the learning process with guided inquiry has fulfilled the effectiveness indicators. The ability of the teacher to manage the learning process has fulfilled the criteria good. In addition, the students’ activity has fulfilled the criteria of, at least, good. Moreover, the students’ responses to the learning device and the learning activities were positive, and the students were able to complete the classical learning. Based on the result of this research, it is expected that the learning device resulted can be used as an alternative learning device for teachers in implementing mathematic learning for comparison topics.

Assessment of occupational exposure due to intakes of radionuclides. Safety guide

International Nuclear Information System (INIS)

2004-01-01

Occupational exposure due to radioactive materials can occur as a result of various human activities. These include work associated with the different stages of the nuclear fuel cycle, the use of radioactive sources in medicine, scientific research, agriculture and industry, and occupations which involve the handling of materials containing enhanced concentrations of naturally occurring radionuclides. In order to control this exposure, it is necessary to be able to assess the magnitude of the doses involved. Three interrelated Safety Guides, prepared jointly by the IAEA and the International Labour Office (ILO), provide guidance on the application of the requirements of the Basic Safety Standards with respect to occupational exposure. Reference [3] gives general advice on the exposure conditions for which monitoring programmes should be set up to assess radiation doses arising from external radiation and from intakes of radionuclides by workers. More specific guidance on the assessment of doses from external sources of radiation can be found in Ref. [4] and the present Safety Guide deals with intakes of radioactive materials. Recommendations related to occupational radiation protection have also been developed by the International Commission on Radiological Protection (ICRP) [5]. These and other current recommendations of the ICRP [6] have been taken into account in preparing this Safety Guide. The purpose of this Safety Guide is to provide guidance for regulatory authorities on conducting assessments of intakes of radioactive material arising from occupational exposure. This Guide will also be useful to those concerned with the planning, management and operation of occupational monitoring programmes, and to those involved in the design of equipment for use in internal dosimetry and workplace monitoring

Assessment of occupational exposure due to intakes of radionuclides. Safety guide

International Nuclear Information System (INIS)

2000-01-01

Occupational exposure due to radioactive materials can occur as a result of various human activities. These include work associated with the different stages of the nuclear fuel cycle, the use of radioactive sources in medicine, scientific research, agriculture and industry, and occupations which involve the handling of materials containing enhanced concentrations of naturally occurring radionuclides. In order to control this exposure, it is necessary to be able to assess the magnitude of the doses involved. Three interrelated Safety Guides, prepared jointly by the IAEA and the International Labour Office (ILO), provide guidance on the application of the requirements of the Basic Safety Standards with respect to occupational exposure. Reference [3] gives general advice on the exposure conditions for which monitoring programmes should be set up to assess radiation doses arising from external radiation and from intakes of radionuclides by workers. More specific guidance on the assessment of doses from external sources of radiation can be found in Ref. [4] and the present Safety Guide deals with intakes of radioactive materials. Recommendations related to occupational radiation protection have also been developed by the International Commission on Radiological Protection (ICRP) [5]. These and other current recommendations of the ICRP [6] have been taken into account in preparing this Safety Guide. The purpose of this Safety Guide is to provide guidance for regulatory authorities on conducting assessments of intakes of radioactive material arising from occupational exposure. This Guide will also be useful to those concerned with the planning, management and operation of occupational monitoring programmes, and to those involved in the design of equipment for use in internal dosimetry and workplace monitoring

Assessment of occupational exposure due to intakes of radionuclides. Safety guide

International Nuclear Information System (INIS)

2001-01-01

Occupational exposure due to radioactive materials can occur as a result of various human activities. These include work associated with the different stages of the nuclear fuel cycle, the use of radioactive sources in medicine, scientific research, agriculture and industry, and occupations which involve the handling of materials containing enhanced concentrations of naturally occurring radionuclides. In order to control this exposure, it is necessary to be able to assess the magnitude of the doses involved. Three interrelated Safety Guides, prepared jointly by the IAEA and the International Labour Office (ILO), provide guidance on the application of the requirements of the Basic Safety Standards with respect to occupational exposure. Reference [3] gives general advice on the exposure conditions for which monitoring programmes should be set up to assess radiation doses arising from external radiation and from intakes of radionuclides by workers. More specific guidance on the assessment of doses from external sources of radiation can be found in Ref. [4] and the present Safety Guide deals with intakes of radioactive materials. Recommendations related to occupational radiation protection have also been developed by the International Commission on Radiological Protection (ICRP) [5]. These and other current recommendations of the ICRP [6] have been taken into account in preparing this Safety Guide. The purpose of this Safety Guide is to provide guidance for regulatory authorities on conducting assessments of intakes of radioactive material arising from occupational exposure. This Guide will also be useful to those concerned with the planning, management and operation of occupational monitoring programmes, and to those involved in the design of equipment for use in internal dosimetry and workplace monitoring

Assessment of occupational exposure due to intakes of radionuclides. Safety guide

International Nuclear Information System (INIS)

2002-01-01

Occupational exposure due to radioactive materials can occur as a result of various human activities. These include work associated with the different stages of the nuclear fuel cycle, the use of radioactive sources in medicine, scientific research, agriculture and industry, and occupations which involve the handling of materials containing enhanced concentrations of naturally occurring radionuclides. In order to control this exposure, it is necessary to be able to assess the magnitude of the doses involved. Three interrelated Safety Guides, prepared jointly by the IAEA and the International Labour Office (ILO), provide guidance on the application of the requirements of the Basic Safety Standards with respect to occupational exposure. Reference [3] gives general advice on the exposure conditions for which monitoring programmes should be set up to assess radiation doses arising from external radiation and from intakes of radionuclides by workers. More specific guidance on the assessment of doses from external sources of radiation can be found in Ref. [4] and the present Safety Guide deals with intakes of radioactive materials. Recommendations related to occupational radiation protection have also been developed by the International Commission on Radiological Protection (ICRP) [5]. These and other current recommendations of the ICRP [6] have been taken into account in preparing this Safety Guide. The purpose of this Safety Guide is to provide guidance for regulatory authorities on conducting assessments of intakes of radioactive material arising from occupational exposure. This Guide will also be useful to those concerned with the planning, management and operation of occupational monitoring programmes, and to those involved in the design of equipment for use in internal dosimetry and workplace monitoring

Assessment of occupational exposure due to intakes of radionuclides. Safety guide

International Nuclear Information System (INIS)

1999-01-01

Occupational exposure due to radioactive materials can occur as a result of various human activities. These include work associated with the different stages of the nuclear fuel cycle, the use of radioactive sources in medicine, scientific research, agriculture and industry, and occupations which involve the handling of materials containing enhanced concentrations of naturally occurring radionuclides. In order to control this exposure, it is necessary to be able to assess the magnitude of the doses involved. Three interrelated Safety Guides, prepared jointly by the IAEA and the International Labour Office (ILO), provide guidance on the application of the requirements of the Basic Safety Standards with respect to occupational exposure. Reference [3] gives general advice on the exposure conditions for which monitoring programmes should be set up to assess radiation doses arising from external radiation and from intakes of radionuclides by workers. More specific guidance on the assessment of doses from external sources of radiation can be found in Ref. [4] and the present Safety Guide deals with intakes of radioactive materials. Recommendations related to occupational radiation protection have also been developed by the International Commission on Radiological Protection (ICRP) [5]. These and other current recommendations of the ICRP [6] have been taken into account in preparing this Safety Guide. The purpose of this Safety Guide is to provide guidance for regulatory authorities on conducting assessments of intakes of radioactive material arising from occupational exposure. This Guide will also be useful to those concerned with the planning, management and operation of occupational monitoring programmes, and to those involved in the design of equipment for use in internal dosimetry and workplace monitoring

Density gradient instabilities in a neutron inhomogeneous guiding-centre plasma

International Nuclear Information System (INIS)

Shoucri, M.M.; Gagne, R.R.J.

1977-01-01

The guiding-centre equations for a plasma of cold ions and thermal electrons admit neutral and non-neutral inhomogeneous equilibrium solutions, and the linear stability of these solutions has been recently investigated numerically by Shoucri and Knorr (1975). With arbitrary density profiles, numerical techniques appear to be the only practical way to study the linear stability of the inhomogeneous equilibrium solutions for the guiding centre plasma. However, analytical methods can be applied to some simple types of density profiles. The purpose of the present note is to present some analytical results on the linear instabilities of an inhomogeneous neutral guiding centre plasma. (U.K.)

Introduction to Artificial Vision through Laboratory Guides Using Matlab

OpenAIRE

Verónica Londoño-Osorio; Jhovana Marín-Pineda; Eliana I. Arango-Zuluaga

2013-01-01

This paper presents the design of two laboratory guides in artificial vision for a course which aims to introduce students to the different areas of specialization of his career. Therefore, the designed practices motivate and provide relevant content to the student, and to encourage research in the area of image processing. The first guide presents an introductory practice that explores the basic commands for image processing by programming a GUI in Matlab, and a second practice in which you ...

Thermal CFD Analysis of Tubular Light Guides

Directory of Open Access Journals (Sweden)

Ondřej Šikula

2013-12-01

Full Text Available Tubular light guides are applicable for daylighting of windowless areas in buildings. Despite their many positive indoor climate aspects they can also present some problems with heat losses and condensation. A computer CFD model focused on the evaluation of temperature distribution and air flow inside tubular light guides of different dimensions was studied. The physical model of the tested light guides of lengths more than 0.60 m proves shows that Rayleigh numbers are adequate for a turbulent air flow. The turbulent model was applied despite the small heat flux differences between the turbulent and laminar model. The CFD simulations resulted into conclusions that the growing ratio of length/diameter increases the heat transmission loss/linear transmittance as much as by 50 percent. Tubular light guides of smaller diameters have lower heat transmission losses compared to the wider ones of the same lengths with the same outdoor temperature being taken into account. The simulation results confirmed the thermal bridge effect of the tubular light guide tube inside the insulated flat roof details. The thermal transmittance of the studied light guides in the whole roof area was substituted with the point thermal bridges. This substitution gives possibility for simple thermal evaluation of the tubular light pipes in roof constructions.

Comprehensive Evaluation and Classification of Interchange Diagrammatic Guide Signs’ Complexity

OpenAIRE

Li, Yang; Zhao, Xiaohua; He, Qing; Huang, Lihua; Rong, Jian

2018-01-01

The effectiveness of interchange diagrammatic guide signs has significant meaning in traffic safety and driver’s understanding. This paper presented a comprehensive evaluation and classification of interchange diagrammatic guide signs’ complexity. The effectiveness of interchange diagrammatic guide signs relies on how well road users can understand those diagrams. This study tested 37 types of diagrams on the visual recognition complexity degree in three levels, general level, partial level, ...

Buying, Preparing, and Cooking Shellfish. Learning Activity Pack and Instructor's Guide 5.13c. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with the various market forms of shellfish and how to clean, prepare, and cook them. Illustrated information sheets and learning activities are provided in these…

L-024: EPR-First Responders: First Responders Monitor Action Guides

International Nuclear Information System (INIS)

2011-01-01

A proceeding guide has been given in this presentation, overall in radiation detection monitoring areas in emergency situations specially personnel involved . The action guide determine when and how it has to monitor an area or people in a emergency situation.

Operational limits and conditions and operating procedures for nuclear power plants. Safety guide

International Nuclear Information System (INIS)

2005-01-01

This Safety Guide was prepared as part of the Agency's programme for establishing safety standards relating to nuclear power plants. The present Safety Guide supersedes the IAEA Safety Guide on Operational Limits and Conditions for Nuclear Power Plants which was issued in 1979 as Safety Series No. 50-SG-O3. For a nuclear power plant to be operated in a safe manner, the provisions made in the final design and subsequent modifications shall be reflected in limitations on plant operating parameters and in the requirements on plant equipment and personnel. Under the responsibility of the operating organization, these shall be developed during the design safety evaluation as a set of operational limits and conditions (OLCs). A major contribution to compliance with the OLCs is made by the development and utilization of operating procedures (OPs) that are consistent with and fully implement the OLCs. The requirements for the OLCs and OPs are established in Section 5 of the IAEA Safety Requirements publication Safety of Nuclear Power Plants: Operation, which this Safety Guide supplements. The purpose of this Safety Guide is to provide guidance on the development, content and implementation of OLCs and OPs. The Safety Guide is directed at both regulators and owners/operators. This Safety Guide covers the concept of OLCs, their content as applicable to land based stationary power plants with thermal neutron reactors, and the responsibilities of the operating organization regarding their establishment, modification, compliance and documentation. The OPs to support the implementation of the OLCs and to ensure their observance are also within the scope of this Safety Guide. The particular aspects of the procedures for maintenance, surveillance, in-service inspection and other safety related activities in connection with the safe operation of nuclear power plants are outside the scope of this Safety Guide but can be found in other IAEA Safety Guides. Section 2 indicates the

Operational limits and conditions and operating procedures for nuclear power plants. Safety guide

International Nuclear Information System (INIS)

2000-01-01

This Safety Guide was prepared as part of the Agency's programme for establishing safety standards relating to nuclear power plants. The present Safety Guide supersedes the IAEA Safety Guide on Operational Limits and Conditions for Nuclear Power Plants which was issued in 1979 as Safety Series No. 50-SG-O3. For a nuclear power plant to be operated in a safe manner, the provisions made in the final design and subsequent modifications shall be reflected in limitations on plant operating parameters and in the requirements on plant equipment and personnel. Under the responsibility of the operating organization, these shall be developed during the design safety evaluation as a set of operational limits and conditions (OLCs). A major contribution to compliance with the OLCs is made by the development and utilization of operating procedures (OPs) that are consistent with and fully implement the OLCs. The requirements for the OLCs and OPs are established in Section 5 of the IAEA Safety Requirements publication Safety of Nuclear Power Plants: Operation, which this Safety Guide supplements. The purpose of this Safety Guide is to provide guidance on the development, content and implementation of OLCs and OPs. The Safety Guide is directed at both regulators and owners/operators. This Safety Guide covers the concept of OLCs, their content as applicable to land based stationary power plants with thermal neutron reactors, and the responsibilities of the operating organization regarding their establishment, modification, compliance and documentation. The OPs to support the implementation of the OLCs and to ensure their observance are also within the scope of this Safety Guide. The particular aspects of the procedures for maintenance, surveillance, in-service inspection and other safety related activities in connection with the safe operation of nuclear power plants are outside the scope of this Safety Guide but can be found in other IAEA Safety Guides. Section 2 indicates the

Guide documentaire pour en savoir plus sur l'informatique (A Documentary Guide to Further Knowledge of Computer Science).

Science.gov (United States)

Achard-Bayle, Guy

1985-01-01

Presents a listing of textbooks, computer program guides, articles, opinion papers, histories, reference works, databases, reviews, bibliographies, organizations, and other information sources concerning computer applications. (MSE)

Standard guide for computed radiography

CERN Document Server

American Society for Testing and Materials. Philadelphia

2010-01-01

1.1 This guide provides general tutorial information regarding the fundamental and physical principles of computed radiography (CR), definitions and terminology required to understand the basic CR process. An introduction to some of the limitations that are typically encountered during the establishment of techniques and basic image processing methods are also provided. This guide does not provide specific techniques or acceptance criteria for specific end-user inspection applications. Information presented within this guide may be useful in conjunction with those standards of 1.2. 1.2 CR techniques for general inspection applications may be found in Practice E2033. Technical qualification attributes for CR systems may be found in Practice E2445. Criteria for classification of CR system technical performance levels may be found in Practice E2446. Reference Images Standards E2422, E2660, and E2669 contain digital reference acceptance illustrations. 1.3 The values stated in SI units are to be regarded as the st...

An Instructor's Guide for a Program in Brake Services.

Science.gov (United States)

New York State Education Dept., Albany. Bureau of Secondary Curriculum Development.

The instructor's guide is designed to present an understanding of the automotive hydraulic brake system and to help individuals develop new skills for employment in this specialized field of automotive service. Applicable for secondary or adult education, this guide describes: the brake system, types of brakes, diagnosis and correction of brake…

Colorado Fathers' Resource Guide = Guia de Recursos para los Padres en Colorado.

Science.gov (United States)

Colorado Foundation for Families and Children, Denver.

Developed through the Colorado Fatherhood Connection, this guide, in English- and Spanish-language versions, provides suggestions and resources for fathers as well as tips on discipline, communication, and activities fathers can do with their children. Topics addressed in the guide include characteristics of responsible fatherhood, characteristics…

KidsWalk-to-School: A Guide To Promote Walking to School.

Science.gov (United States)

Center for Chronic Disease Prevention and Health Promotion (DHHS/CDC), Atlanta, GA.

This guide encourages people to create safe walking and biking routes to school, promoting four issues: physically active travel, safe and walkable routes to school, crime prevention, and health environments. The chapters include: "KidsWalk-to-School: A Guide to Promote Walking to School" (Is there a solution? Why is walking to school important?…

Activity-based cost analysis of hepatic tumor ablation using CT-guided high-dose rate brachytherapy or CT-guided radiofrequency ablation in hepatocellular carcinoma.

Science.gov (United States)

Schnapauff, D; Collettini, F; Steffen, I; Wieners, G; Hamm, B; Gebauer, B; Maurer, M H

2016-02-25

To analyse and compare the costs of hepatic tumor ablation with computed tomography (CT)-guided high-dose rate brachytherapy (CT-HDRBT) and CT-guided radiofrequency ablation (CT-RFA) as two alternative minimally invasive treatment options of hepatocellular carcinoma (HCC). An activity based process model was created determining working steps and required staff of CT-RFA and CT-HDRBT. Prorated costs of equipment use (purchase, depreciation, and maintenance), costs of staff, and expenditure for disposables were identified in a sample of 20 patients (10 treated by CT-RFA and 10 by CT-HDRBT) and compared. A sensitivity and break even analysis was performed to analyse the dependence of costs on the number of patients treated annually with both methods. Costs of CT-RFA were nearly stable with mean overall costs of approximately 1909 €, 1847 €, 1816 € and 1801 € per patient when treating 25, 50, 100 or 200 patients annually, as the main factor influencing the costs of this procedure was the single-use RFA probe. Mean costs of CT-HDRBT decreased significantly per patient ablation with a rising number of patients treated annually, with prorated costs of 3442 €, 1962 €, 1222 € and 852 € when treating 25, 50, 100 or 200 patients, due to low costs of single-use disposables compared to high annual fix-costs which proportionally decreased per patient with a higher number of patients treated annually. A break-even between both methods was reached when treating at least 55 patients annually. Although CT-HDRBT is a more complex procedure with more staff involved, it can be performed at lower costs per patient from the perspective of the medical provider when treating more than 55 patients compared to CT-RFA, mainly due to lower costs for disposables and a decreasing percentage of fixed costs with an increasing number of treatments.

Civil Engineering Technology Program Guide.

Science.gov (United States)

Georgia Univ., Athens. Dept. of Vocational Education.

This program guide presents civil engineering technology curriculum for technical institutes in Georgia. The general information section contains the following: purpose and objectives; program description, including admissions, typical job titles, and accreditation and certification; and curriculum model, including standard curriculum sequence and…

Standard guide for high-resolution gamma-ray spectrometry of soil samples

CERN Document Server

American Society for Testing and Materials. Philadelphia

2004-01-01

1.1 This guide covers the identification and quantitative determination of gamma-ray emitting radionuclides in soil samples by means of gamma-ray spectrometry. It is applicable to nuclides emitting gamma rays with an approximate energy range of 20 to 2000 keV. For typical gamma-ray spectrometry systems and sample types, activity levels of about 5 Bq (135 pCi) are measured easily for most nuclides, and activity levels as low as 0.1 Bq (2.7 pCi) can be measured for many nuclides. It is not applicable to radionuclides that emit no gamma rays such as the pure beta-emitting radionuclides hydrogen-3, carbon-14, strontium-90, and becquerel quantities of most transuranics. This guide does not address the in situ measurement techniques, where soil is analyzed in place without sampling. Guidance for in situ techniques can be found in Ref (1) and (2). This guide also does not discuss methods for determining lower limits of detection. Such discussions can be found in Refs (3), (4), (5), and (6). 1.2 This guide can be us...

Pathways to a Sustainable Future: A Curriculum Guide for Maine Schools Exploring Waste Management Issues.

Science.gov (United States)

Chewonki Foundation, Wiscasset, ME.

This action guide is designed to help students and teachers become aware of the concepts and issues of waste management, and to motivate them to action in the classroom, school, home, and community. The guide emphasizes interdisciplinary activities that concentrate on the process of problem solving. Activities are identified by appropriate grade…

Dining Room Service/Clearing and Cleaning Tables. Learning Activity Pack and Instructor's Guide 8.1c. Commercial Foods and Culinary Arts Competency-Based Series. Section 8: Related Services.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with efficient table clearing and cleaning duties. Illustrated information sheets and learning activities are provided in these areas: table clearing and cleaning…

Reassessing Occupational Licensing Of Tour Guides (Opinion Piece

Directory of Open Access Journals (Sweden)

Amir SHANI

2017-06-01

Full Text Available It is conventionally held that to protect tourists from incompetent and/or unscrupulous tour guides, governments should require guides to be licensed in order to legally practice their profession. Despite the implementation of such regulatory statutes in many countries, it is argued in this opinion paper that the severe drawbacks of licensing demands should be re-evaluated by both policy-makers and tourism scholars. The licensing of guides is not only an ineffective means of quality assurance, with negative consequences for many of those involved, but it also undermines the ethical foundations of a free society. Furthermore, licensing is an archaic practice for ensuring standardization among the members of a profession in a way that is no longer suitable for addressing the challenges of the tourism industry in the 21st century, in which a wide variety of specialized and innovative guided tours are offered to tourists. Although this commentary presents a firm stand against the compulsory licensing of tour guides, it should be seen as an invitation for open discussion among tourism researchers regarding the necessity of licensing tour guides in particular, and of government tourism regulation in general. Moreover, further research is needed to clarify key points on the issue of the professional licensing of tour guides.

CNN Newsroom Classroom Guides, October 2000.

Science.gov (United States)

Turner Educational Services, Inc., Newtown, PA.

These classroom guides, designed to accompany the daily CNN (Cable News Network) Newsroom broadcasts for the month of October 2000, provide program rundowns, suggestions for class activities and discussion, student handouts, and a list of related news terms. Top stories include: Chinese authorities detain Falun Gong protesters on Tiananmen Square…

The Universe Discovery Guides: A Collaborative Approach to Educating with NASA Science

Science.gov (United States)

Manning, James G.; Lawton, Brandon L.; Gurton, Suzanne; Smith, Denise Anne; Schultz, Gregory; Astrophysics Community, NASA

2015-08-01

For the 2009 International Year of Astronomy, the then-existing NASA Origins Forum collaborated with the Astronomical Society of the Pacific (ASP) to create a series of monthly “Discovery Guides” for informal educator and amateur astronomer use in educating the public about featured sky objects and associated NASA science themes. Today’s NASA Astrophysics Science Education and Public Outreach Forum (SEPOF), one of the current generation of forums coordinating the work of NASA Science Mission Directorate (SMD) EPO efforts—in collaboration with the ASP and NASA SMD missions and programs--has adapted the Discovery Guides into “evergreen” educational resources suitable for a variety of audiences. The Guides focus on “deep sky” objects and astrophysics themes (stars and stellar evolution, galaxies and the universe, and exoplanets), showcasing EPO resources from more than 30 NASA astrophysics missions and programs in a coordinated and cohesive “big picture” approach across the electromagnetic spectrum, grounded in best practices to best serve the needs of the target audiences.Each monthly guide features a theme and a representative object well-placed for viewing, with an accompanying interpretive story, finding charts, strategies for conveying the topics, and complementary supporting NASA-approved education activities and background information from a spectrum of NASA missions and programs. The Universe Discovery Guides are downloadable from the NASA Night Sky Network web site at nightsky.jpl.nasa.gov and specifically from http://nightsky.jpl.nasa.gov/news-display.cfm?News_ID=611.The presentation will describe the collaborative’s experience in developing the guides, how they place individual science discoveries and learning resources into context for audiences, and how the Guides can be readily used in scientist public outreach efforts, in college and university introductory astronomy classes, and in other engagements between scientists, instructors

Buying, Preparing, and Cooking Fish. Learning Activity Pack and Instructor's Guide 5.13b. Commercial Foods and Culinary Arts Competency-Based Series. Section 5: Basic Food Preparation.

Science.gov (United States)

Florida State Univ., Tallahassee. Center for Studies in Vocational Education.

This document consists of a learning activity packet (LAP) for the student and an instructor's guide for the teacher. The LAP is intended to acquaint occupational home economics students with the market forms of fish, how to clean and portion them, and how to cook them. Illustrated information sheets and learning activities are provided in these…

A guide to experimental particle physics literature, 1991-1996

International Nuclear Information System (INIS)

Ezhela, V.V.; Filimonov, B.B.; Lugovsky, S.B.

1996-10-01

We present an indexed guide to experimental particle physics literature for the years 1991 - 1996. Approximately 4200 papers are indexed by (1) Beam/Target/Momentum (2) Reaction/Momentum/Data-Descriptor (including the final state) (3) Particle/Decay (4) Accelerator/Experiment/Detector. All indices are cross-referenced to the paper''s title and references in the ID/Reference/Title index. The information presented in this guide is also publicly available on a regularly-updated DATAGUIDE database from the World Wide Web

A guide to experimental particle physics literature, 1991-1996

Energy Technology Data Exchange (ETDEWEB)

Ezhela, V.V.; Filimonov, B.B.; Lugovsky, S.B. [Inst. for High Energy Physics, Moscow (Russian Federation)] [and others

1996-10-01

We present an indexed guide to experimental particle physics literature for the years 1991 - 1996. Approximately 4200 papers are indexed by (1) Beam/Target/Momentum (2) Reaction/Momentum/Data-Descriptor (including the final state) (3) Particle/Decay (4) Accelerator/Experiment/Detector. All indices are cross-referenced to the paper`s title and references in the ID/Reference/Title index. The information presented in this guide is also publicly available on a regularly-updated DATAGUIDE database from the World Wide Web.

Design of the Mechanical Parts for the Neutron Guide System at HANARO

International Nuclear Information System (INIS)

Shin, J. W.; Cho, Y. G.; Cho, S. J.; Ryu, J. S.

2008-01-01

The research reactor HANARO (High-flux Advanced Neutron Application ReactOr) in Korea will be equipped with a neutron guide system, in order to transport cold neutrons from the neutron source to the neutron scattering instruments in the neutron guide hall near the reactor building. The neutron guide system of HANARO consists of the in-pile plug assembly with in-pile guides, the primary shutter with in-shutter guides, the neutron guides in the guide shielding room with dedicated secondary shutters, and the neutron guides connected to the instruments in the neutron guide hall. Functions of the in-pile plug assembly are to shield the reactor environment from nuclear radiation and to support the neutron guides and maintain them precisely oriented. The primary shutter is a mechanical structure to be installed just after the in-pile plug assembly, which stops neutron flux on demand. This paper describes the design of the in-pile assembly and the primary shutter for the neutron guide system at HANARO. The design of the guide shielding assembly for the primary shutter and the neutron guides is also presented

Distinct Hippocampal versus Frontoparietal Network Contributions to Retrieval and Memory-guided Exploration.

Science.gov (United States)

Bridge, Donna J; Cohen, Neal J; Voss, Joel L

2017-08-01

Memory can profoundly influence new learning, presumably because memory optimizes exploration of to-be-learned material. Although hippocampus and frontoparietal networks have been implicated in memory-guided exploration, their specific and interactive roles have not been identified. We examined eye movements during fMRI scanning to identify neural correlates of the influences of memory retrieval on exploration and learning. After retrieval of one object in a multiobject array, viewing was strategically directed away from the retrieved object toward nonretrieved objects, such that exploration was directed toward to-be-learned content. Retrieved objects later served as optimal reminder cues, indicating that exploration caused memory to become structured around the retrieved content. Hippocampal activity was associated with memory retrieval, whereas frontoparietal activity varied with strategic viewing patterns deployed after retrieval, thus providing spatiotemporal dissociation of memory retrieval from memory-guided learning strategies. Time-lagged fMRI connectivity analyses indicated that hippocampal activity predicted frontoparietal activity to a greater extent for a condition in which retrieval guided exploration occurred than for a passive control condition in which exploration was not influenced by retrieval. This demonstrates network-level interaction effects specific to influences of memory on strategic exploration. These findings show how memory guides behavior during learning and demonstrate distinct yet interactive hippocampal-frontoparietal roles in implementing strategic exploration behaviors that determine the fate of evolving memory representations.

Distinct hippocampal versus frontoparietal-network contributions to retrieval and memory-guided exploration

Science.gov (United States)

Bridge, Donna J.; Cohen, Neal J.; Voss, Joel L.

2017-01-01

Memory can profoundly influence new learning, presumably because memory optimizes exploration of to-be-learned material. Although hippocampus and frontoparietal networks have been implicated in memory-guided exploration, their specific and interactive roles have not been identified. We examined eye movements during fMRI scanning to identify neural correlates of the influences of memory retrieval on exploration and learning. Following retrieval of one object in a multi-object array, viewing was strategically directed away from the retrieved object toward non-retrieved objects, such that exploration was directed towards to-be-learned content. Retrieved objects later served as optimal reminder cues, indicating that exploration caused memory to become structured around the retrieved content. Hippocampal activity was associated with memory retrieval whereas frontoparietal activity varied with strategic viewing patterns deployed following retrieval, thus providing spatiotemporal dissociation of memory retrieval from memory-guided learning strategies. Time-lagged fMRI connectivity analyses indicated that hippocampal activity predicted frontoparietal activity to a greater extent for a condition in which retrieval guided exploration than for a passive control condition in which exploration was not influenced by retrieval. This demonstrates network-level interaction effects specific to influences of memory on strategic exploration. These findings show how memory guides behavior during learning and demonstrate distinct yet interactive hippocampal-frontoparietal roles in implementing strategic exploration behaviors that determine the fate of evolving memory representations. PMID:28471729

Ariadne: a Java-based guided tour system for the World Wide Web

DEFF Research Database (Denmark)

Jühne, Jesper; Jensen, Anders T.; Grønbæk, Kaj

1998-01-01

This paper presents a Guided tour system for the WWW, called Ariadne, which implements the ideas of trails and guided tours, originating from the hypertext field. Ariadne appears as a Java applet to the user and it stores guided tours in a database format separated from the WWW documents included...

Regulatory and law framework of agricultural methanization and composting activities. User's guide; Le cadre reglementaire et juridique des activites agricoles de methanisation et de compostage. Guide Pratique

Energy Technology Data Exchange (ETDEWEB)

NONE

2008-08-15

After a presentation of the general context of organic waste management (its techniques, materials, legal and regulatory sources, i.e. European and French laws), this guide indicates the main regulatory and law aspects to those wishing to implement a project of methanization or composting of organic by-products in the agricultural sector. Several aspects are therefore discussed and presented in practical sheets. They concern the health and environment regulation, but not the professional risk prevention (explosion, fire, and so on). These aspects are the project setting up, input materials (animal by-products, organic materials coming from agricultural production or from out of it), waste collection and transport, process steps, organic product valorization, biogas valorization, solid and liquid release management

Ontario hydro radioactive material transportation field guide

International Nuclear Information System (INIS)

Howe, W.

1987-01-01

The recent introduction of both the AECB Transport Packaging of Radioactive Material Regulations and Transport Canada's Transportation of Dangerous Goods Regulations have significantly altered the requirements for transporting radioactive material in Canada. Extensive additional training as well as certification of several hundred Ontario Hydro employees has been necessary to ensure compliance with the additional and revised regulatory requirements. To assist in the training of personnel, an 'active' corporate Ontario Hydro Field Guide for Radioactive Material Transport document has been developed and published. The contents of this Field Guide identify current Ontario Hydro equipment and procedures as well as the updated relevant regulatory requirements within Canada. In addition, to satisfying Ontario Hydro requirements for this type of information over two thousand of these Field Guides have been provided to key emergency response personnel throughout the province of Ontario to assist in their transportation accident response training

[Neuronal activity of monkey dorso-lateral premotor cortex during tasks of figure recognition guided motor sequence vs memorized spatial motor sequence].

Science.gov (United States)

Chen, Y C; Huang, F D; Chen, N H; Shou, J Y; Wu, L

1998-04-01

In the last 2-3 decades the role of the premotor cortex (PM) of monkey in memorized spatial sequential (MSS) movements has been amply investigated. However, it is as yet not known whether PM participates in the movement sequence behaviour guided by recognition of visual figures (i.e. the figure-recognition sequence, FRS). In the present work three monkeys were trained to perform both FRS and MSS tasks. Postmortem examination showed that 202 cells were in the dorso-lateral premotor cortex. Among 111 cells recorded during the two tasks, more than 50% changed their activity during the cue periods in either task. During the response period, the ratios of cells with changes of firing rate in both FRS and MSS were high and roughly equal to each other, while during the image period, the proportion in the FRS (83.7%) was significantly higher than that in the MSS (66.7%). Comparison of neuronal activities during same motor sequence of two different tasks showed that during the image periods PM neuronal activities were more closely related to the FRS task, while during the cue periods no difference could be found. Analysis of cell responses showed that the neurons with longer latency were much more in MSS than in FRS in either cue or image period. The present results indicate that the premotor cortex participates in FRS motor sequence as well as in MSS and suggest that the dorso-lateral PM represents another subarea in function shared by both FRS and MSS tasks. However, in view of the differences of PM neuronal responses in cue or image periods of FRS and MSS tasks, it seems likely that neural networks involved in FRS and MSS tasks are different.

Healthy Water, Healthy Habits, Healthy People Educators Guide

Science.gov (United States)

Project WET Foundation, 2008

2008-01-01

Clean water, proper sanitation and good hygiene form a solid foundation for a student's health education. This activities guide is designed to enable teachers to take an active role in making a real difference in the lives of children and their families. Its 40 pages are filled with engaging ways to impart an understanding about how common…

Geometry of surfaces a practical guide for mechanical engineers

CERN Document Server

Radzevich, Stephen P

2012-01-01

Presents an in-depth analysis of geometry of part surfaces and provides the tools for solving complex engineering problems Geometry of Surfaces: A Practical Guide for Mechanical Engineers is a comprehensive guide to applied geometry of surfaces with focus on practical applications in various areas of mechanical engineering. The book is divided into three parts on Part Surfaces, Geometry of Contact of Part Surfaces and Mapping of the Contacting Part Surfaces. Geometry of Surfaces: A Practical Guide for Mechanical Engineers combines differential geometry and gearing theory and presents new developments in the elementary theory of enveloping surfaces. Written by a leading expert of the field, this book also provides the reader with the tools for solving complex engineering problems in the field of mechanical engineering. Presents an in-depth analysis of geometry of part surfaces Provides tools for solving complex engineering problems in the field of mechanical engineering Combines differential geometry an...

An Integrated User Interface Style Guide for the ESF-CCS, RPS and CPCS display design

International Nuclear Information System (INIS)

Park, Jae Kyu; Lee, Hyun Chul; Hwang, Seong Hwan; Jang, Tong Il; Kang, Suk Ho; Lee, Jung Woon; Lee, Yong Hee

2009-01-01

The human machine interface (HMI) design process is important to enhance the safety and reliability of a Nuclear Power Plant (NPP) operation. Various MMI activities are achieved with progress of MMI and environment of NPP. These activities are impossible to utilize when upgrade of environment because most of these activities emphasize hardware aspect. Also, the human factors guidelines mostly describe the human factors principles so the designer has to adapt them to apply them to his design. The design-specific guideline that is specially dedicated to a unique system and derived from the general guidelines is called style guide. The style guide provides easy to use templates to help the user interface design, and these templates help ensure a consistent look and behavior throughout the design products. However, it could be difficult for a designer to select the human factors guideline items related to a target system and to derive a style guide from the items. This paper describes human factors activities carried out to develop a style guide for the ESF-CCS, RPS and CPCS system

Intro to Valve Guide Reconditioning. Automotive Mechanics. Valves. Instructor's Guide [and] Student Guide.