WorldWideScience

Sample records for active region generate

  1. Genome-Based Identification of Active Prophage Regions by Next Generation Sequencing in Bacillus licheniformis DSM13

    Science.gov (United States)

    Hertel, Robert; Rodríguez, David Pintor; Hollensteiner, Jacqueline; Dietrich, Sascha; Leimbach, Andreas; Hoppert, Michael; Liesegang, Heiko; Volland, Sonja

    2015-01-01

    Prophages are viruses, which have integrated their genomes into the genome of a bacterial host. The status of the prophage genome can vary from fully intact with the potential to form infective particles to a remnant state where only a few phage genes persist. Prophages have impact on the properties of their host and are therefore of great interest for genomic research and strain design. Here we present a genome- and next generation sequencing (NGS)-based approach for identification and activity evaluation of prophage regions. Seven prophage or prophage-like regions were identified in the genome of Bacillus licheniformis DSM13. Six of these regions show similarity to members of the Siphoviridae phage family. The remaining region encodes the B. licheniformis orthologue of the PBSX prophage from Bacillus subtilis. Analysis of isolated phage particles (induced by mitomycin C) from the wild-type strain and prophage deletion mutant strains revealed activity of the prophage regions BLi_Pp2 (PBSX-like), BLi_Pp3 and BLi_Pp6. In contrast to BLi_Pp2 and BLi_Pp3, neither phage DNA nor phage particles of BLi_Pp6 could be visualized. However, the ability of prophage BLi_Pp6 to generate particles could be confirmed by sequencing of particle-protected DNA mapping to prophage locus BLi_Pp6. The introduced NGS-based approach allows the investigation of prophage regions and their ability to form particles. Our results show that this approach increases the sensitivity of prophage activity analysis and can complement more conventional approaches such as transmission electron microscopy (TEM). PMID:25811873

  2. Optimization based on benefit of regional energy suppliers of distributed generation in active distribution network

    Science.gov (United States)

    Huo, Xianxu; Li, Guodong; Jiang, Ling; Wang, Xudong

    2017-08-01

    With the development of electricity market, distributed generation (DG) technology and related policies, regional energy suppliers are encouraged to build DG. Under this background, the concept of active distribution network (ADN) is put forward. In this paper, a bi-level model of intermittent DG considering benefit of regional energy suppliers is proposed. The objective of the upper level is the maximization of benefit of regional energy suppliers. On this basis, the lower level is optimized for each scene. The uncertainties of DG output and load of users, as well as four active management measures, which include demand-side management, curtailing the output power of DG, regulating reactive power compensation capacity and regulating the on-load tap changer, are considered. Harmony search algorithm and particle swarm optimization are combined as a hybrid strategy to solve the model. This model and strategy are tested with IEEE-33 node system, and results of case study indicate that the model and strategy successfully increase the capacity of DG and benefit of regional energy suppliers.

  3. VOLCANIC TSUNAMI GENERATING SOURCE MECHANISMS IN THE EASTERN CARIBBEAN REGION

    Directory of Open Access Journals (Sweden)

    George Pararas-Carayannis

    2004-01-01

    Full Text Available Earthquakes, volcanic eruptions, volcanic island flank failures and underwater slides have generated numerous destructive tsunamis in the Caribbean region. Convergent, compressional and collisional tectonic activity caused primarily from the eastward movement of the Caribbean Plate in relation to the North American, Atlantic and South American Plates, is responsible for zones of subduction in the region, the formation of island arcs and the evolution of particular volcanic centers on the overlying plate. The inter-plate tectonic interaction and deformation along these marginal boundaries result in moderate seismic and volcanic events that can generate tsunamis by a number of different mechanisms. The active geo-dynamic processes have created the Lesser Antilles, an arc of small islands with volcanoes characterized by both effusive and explosive activity. Eruption mechanisms of these Caribbean volcanoes are complex and often anomalous. Collapses of lava domes often precede major eruptions, which may vary in intensity from Strombolian to Plinian. Locally catastrophic, short-period tsunami-like waves can be generated directly by lateral, direct or channelized volcanic blast episodes, or in combination with collateral air pressure perturbations, nuéss ardentes, pyroclastic flows, lahars, or cascading debris avalanches. Submarine volcanic caldera collapses can also generate locally destructive tsunami waves. Volcanoes in the Eastern Caribbean Region have unstable flanks. Destructive local tsunamis may be generated from aerial and submarine volcanic edifice mass edifice flank failures, which may be triggered by volcanic episodes, lava dome collapses, or simply by gravitational instabilities. The present report evaluates volcanic mechanisms, resulting flank failure processes and their potential for tsunami generation. More specifically, the report evaluates recent volcanic eruption mechanisms of the Soufriere Hills volcano on Montserrat, of Mt. Pel

  4. The 17 GHz active region number

    Energy Technology Data Exchange (ETDEWEB)

    Selhorst, C. L.; Pacini, A. A. [IP and D-Universidade do Vale do Paraíba-UNIVAP, São José dos Campos (Brazil); Costa, J. E. R. [CEA, Instituto Nacional de Pesquisas Espaciais, São José dos Campos (Brazil); Giménez de Castro, C. G.; Valio, A. [CRAAM, Universidade Presbiteriana Mackenzie, São Paulo (Brazil); Shibasaki, K., E-mail: caius@univap.br [Nobeyama Solar Radio Observatory/NAOJ, Minamisaku, Nagano 384-1305 (Japan)

    2014-08-01

    We report the statistics of the number of active regions (NAR) observed at 17 GHz with the Nobeyama Radioheliograph between 1992, near the maximum of cycle 22, and 2013, which also includes the maximum of cycle 24, and we compare with other activity indexes. We find that NAR minima are shorter than those of the sunspot number (SSN) and radio flux at 10.7 cm (F10.7). This shorter NAR minima could reflect the presence of active regions generated by faint magnetic fields or spotless regions, which were a considerable fraction of the counted active regions. The ratio between the solar radio indexes F10.7/NAR shows a similar reduction during the two minima analyzed, which contrasts with the increase of the ratio of both radio indexes in relation to the SSN during the minimum of cycle 23-24. These results indicate that the radio indexes are more sensitive to weaker magnetic fields than those necessary to form sunspots, of the order of 1500 G. The analysis of the monthly averages of the active region brightness temperatures shows that its long-term variation mimics the solar cycle; however, due to the gyro-resonance emission, a great number of intense spikes are observed in the maximum temperature study. The decrease in the number of these spikes is also evident during the current cycle 24, a consequence of the sunspot magnetic field weakening in the last few years.

  5. Estimation of regional building-related C&D debris generation and composition: case study for Florida, US.

    Science.gov (United States)

    Cochran, Kimberly; Townsend, Timothy; Reinhart, Debra; Heck, Howell

    2007-01-01

    Methodology for the accounting, generation, and composition of building-related construction and demolition (C&D) at a regional level was explored. Six specific categories of debris were examined: residential construction, nonresidential construction, residential demolition, nonresidential demolition, residential renovation, and nonresidential renovation. Debris produced from each activity was calculated as the product of the total area of activity and waste generated per unit area of activity. Similarly, composition was estimated as the product of the total area of activity and the amount of each waste component generated per unit area. The area of activity was calculated using statistical data, and individual site studies were used to assess the average amount of waste generated per unit area. The application of the methodology was illustrated using Florida, US approximately 3,750,000 metric tons of building-related C&D debris were estimated as generated in Florida in 2000. Of that amount, concrete represented 56%, wood 13%, drywall 11%, miscellaneous debris 8%, asphalt roofing materials 7%, metal 3%, cardboard 1%, and plastic 1%. This model differs from others because it accommodates regional construction styles and available data. The resulting generation amount per capita is less than the US estimate - attributable to the high construction, low demolition activity seen in Florida.

  6. Model-based automatic generation of grasping regions

    Science.gov (United States)

    Bloss, David A.

    1993-01-01

    The problem of automatically generating stable regions for a robotic end effector on a target object, given a model of the end effector and the object is discussed. In order to generate grasping regions, an initial valid grasp transformation from the end effector to the object is obtained based on form closure requirements, and appropriate rotational and translational symmetries are associated with that transformation in order to construct a valid, continuous grasping region. The main result of this algorithm is a list of specific, valid grasp transformations of the end effector to the target object, and the appropriate combinations of translational and rotational symmetries associated with each specific transformation in order to produce a continuous grasp region.

  7. Experimental investigation of auroral generator regions with conjugate Cluster and FAST data

    Directory of Open Access Journals (Sweden)

    O. Marghitu

    2006-03-01

    Full Text Available Here and in the companion paper, Hamrin et al. (2006, we present experimental evidence for the crossing of auroral generator regions, based on conjugate Cluster and FAST data. To our knowledge, this is the first investigation that concentrates on the evaluation of the power density, E·J, in auroral generator regions, by using in-situ measurements. The Cluster data we discuss were collected within the Plasma Sheet Boundary Layer (PSBL, during a quiet magnetospheric interval, as judged from the geophysical indices, and several minutes before the onset of a small substorm, as indicated by the FAST data. Even at quiet times, the PSBL is an active location: electric fields are associated with plasma motion, caused by the dynamics of the plasma-sheet/lobe interface, while electrical currents are induced by pressure gradients. In the example we show, these ingredients do indeed sustain the conversion of mechanical energy into electromagnetic energy, as proved by the negative power density, E·J<0. The plasma characteristics in the vicinity of the generator regions indicate a complicated 3-D wavy structure of the plasma sheet boundary. Consistent with this structure, we suggest that at least part of the generated electromagnetic energy is carried away by Alfvén waves, to be dissipated in the ionosphere, near the polar cap boundary. Such a scenario is supported by the FAST data, which show energetic electron precipitation conjugated with the generator regions crossed by Cluster. A careful examination of the conjunction timing contributes to the validation of the generator signatures.

  8. Spatio-temporal analysis of regional PV generation

    DEFF Research Database (Denmark)

    Nuño Martinez, Edgar; Cutululis, Nicolaos Antonio

    2016-01-01

    Photovoltaic (PV) power is growing in importance worldwide and hence needs to be represented in operation and planning of power system. As opposed to traditional generation technologies, it is characterized by exhibiting both a high variability and a significant spatial dependence. This paper...... presents a fundamental analysis of regional solar generation time series, aiming to potentially facilitate large-scale solar integration. It will focus on characterizing the underlying dependence structure at the system level as well as describing both statistical and temporal properties of regional PV...

  9. Experimental investigation of auroral generator regions with conjugate Cluster and FAST data

    Directory of Open Access Journals (Sweden)

    O. Marghitu

    2006-03-01

    Full Text Available Here and in the companion paper, Hamrin et al. (2006, we present experimental evidence for the crossing of auroral generator regions, based on conjugate Cluster and FAST data. To our knowledge, this is the first investigation that concentrates on the evaluation of the power density, E·J, in auroral generator regions, by using in-situ measurements. The Cluster data we discuss were collected within the Plasma Sheet Boundary Layer (PSBL, during a quiet magnetospheric interval, as judged from the geophysical indices, and several minutes before the onset of a small substorm, as indicated by the FAST data. Even at quiet times, the PSBL is an active location: electric fields are associated with plasma motion, caused by the dynamics of the plasma-sheet/lobe interface, while electrical currents are induced by pressure gradients. In the example we show, these ingredients do indeed sustain the conversion of mechanical energy into electromagnetic energy, as proved by the negative power density, E·J<0. The plasma characteristics in the vicinity of the generator regions indicate a complicated 3-D wavy structure of the plasma sheet boundary. Consistent with this structure, we suggest that at least part of the generated electromagnetic energy is carried away by Alfvén waves, to be dissipated in the ionosphere, near the polar cap boundary. Such a scenario is supported by the FAST data, which show energetic electron precipitation conjugated with the generator regions crossed by Cluster. A careful examination of the conjunction timing contributes to the validation of the generator signatures.

  10. Active region structures in the transition region and corona

    International Nuclear Information System (INIS)

    Webb, D.F.

    1981-01-01

    Observational aspects of the transition region and coronal structures of the solar active region are reviewed with an emphasis on imaging of the plasma loops which act as tracers of the magnetic flux loops. The study of the basic structure of an active region is discussed in terms of the morphological and thermal classifications of active region loops, including umbral structures, and observational knowledge of the thermal structure of loops is considered in relation to scaling laws, emission measures and the structures of individual loops. The temporal evolution of active region loop structures is reviewed with emphasis on ephemeral regions and the emergence of active regions. Planned future spaceborne observations of active region loop structures in the EUV and soft X-ray regions are also indicated

  11. Recurrent activity in higher order, modality non-specific brain regions

    DEFF Research Database (Denmark)

    Lou, Hans Olav Christensen; Joensson, Morten; Biermann-Ruben, Katja

    2011-01-01

    It has been proposed that the workings of the brain are mainly intrinsically generated recurrent neuronal activity, with sensory inputs as modifiers of such activity in both sensory and higher order modality non-specific regions. This is supported by the demonstration of recurrent neuronal activity...... in the visual system as a response to visual stimulation. In contrast recurrent activity has never been demonstrated before in higher order modality non-specific regions. Using magneto-encephalography and Granger causality analysis, we tested in a paralimbic network the hypothesis that stimulation may enhance...... causal recurrent interaction between higher-order, modality non-specific regions. The network includes anterior cingulate/medial prefrontal and posterior cingulate/medial parietal cortices together with pulvinar thalami, a network known to be effective in autobiographic memory retrieval and self...

  12. Generating region proposals for histopathological whole slide image retrieval.

    Science.gov (United States)

    Ma, Yibing; Jiang, Zhiguo; Zhang, Haopeng; Xie, Fengying; Zheng, Yushan; Shi, Huaqiang; Zhao, Yu; Shi, Jun

    2018-06-01

    Content-based image retrieval is an effective method for histopathological image analysis. However, given a database of huge whole slide images (WSIs), acquiring appropriate region-of-interests (ROIs) for training is significant and difficult. Moreover, histopathological images can only be annotated by pathologists, resulting in the lack of labeling information. Therefore, it is an important and challenging task to generate ROIs from WSI and retrieve image with few labels. This paper presents a novel unsupervised region proposing method for histopathological WSI based on Selective Search. Specifically, the WSI is over-segmented into regions which are hierarchically merged until the WSI becomes a single region. Nucleus-oriented similarity measures for region mergence and Nucleus-Cytoplasm color space for histopathological image are specially defined to generate accurate region proposals. Additionally, we propose a new semi-supervised hashing method for image retrieval. The semantic features of images are extracted with Latent Dirichlet Allocation and transformed into binary hashing codes with Supervised Hashing. The methods are tested on a large-scale multi-class database of breast histopathological WSIs. The results demonstrate that for one WSI, our region proposing method can generate 7.3 thousand contoured regions which fit well with 95.8% of the ROIs annotated by pathologists. The proposed hashing method can retrieve a query image among 136 thousand images in 0.29 s and reach precision of 91% with only 10% of images labeled. The unsupervised region proposing method can generate regions as predictions of lesions in histopathological WSI. The region proposals can also serve as the training samples to train machine-learning models for image retrieval. The proposed hashing method can achieve fast and precise image retrieval with small amount of labels. Furthermore, the proposed methods can be potentially applied in online computer-aided-diagnosis systems. Copyright

  13. Thoughts on the development of active regional public health systems.

    Science.gov (United States)

    Reis, Ademar Arthur Chioro Dos; Sóter, Ana Paula Menezes; Furtado, Lumena Almeida Castro; Pereira, Silvana Souza da Silva

    2017-04-01

    Decentralization and regionalization are strategic themes for reforms in the health system. This paper analyzes the complex process of health regionalization being developed in Brazil. This paper identifies that the normative framework from the Brazilian National Health System, SUS has made advances with respect to its institutionalization and overcoming the initial centrality involved in municipalization. This has strengthened the development of regionalization and the intergovernmental agreement on health but the evidence points to the need to promote a revision. Based on document analysis, literature review and the views given by the authors involved in management in SUS as well as generating radically different views, the challenges for the construction of a regionalization that is active, is debated. We also discuss: its relations with planning and the dimensioning of service networks, the production of active care networks and shared management spaces, the inter-federative agreements and regional regulations, the capacity to coordinate regional systems and financing and the impact of the political dimension and electoral cycles. Regionalization (and SUS itself) is an open book, therefore ways and possibilities on how to maintain an active form of regionalization can be recommended.

  14. Proposal of electric power generation from generators to water edge in the region of Sarapiqui

    International Nuclear Information System (INIS)

    Rodriguez Fallas, Cindy Veronica

    2013-01-01

    A proposed electric power generation is developed from generators to water edge in the region of Sarapiqui. The environmental characteristics, such as the hydrological network, hydrogeology, soil type, life zones, climatology, precipitation, temperature, evapotranspiration and water supply and demand, of rivers crossed by basin in the region of Sarapiqui, are determined by bibliographic consultations to implement the proposal. The most recent production statistics of the electric subsector of Costa Rica are described to reveal the growing annual demand and need for satisfaction. The zone of Sarapiqui is diagnosed as the right place to allow the generation of electric power from generators to water edge [es

  15. Solar power generation in a rural region

    International Nuclear Information System (INIS)

    1991-01-01

    The book contains the papers discussions and results of a German/Senegalese seminar on photovoltaic power generation in rural regions of Senegal which was held in Dakar on 19-23 November 1990. (HP) [de

  16. Active regions, ch. 7

    International Nuclear Information System (INIS)

    Martres, M.J.; Bruzek, A.

    1977-01-01

    The solar Active Region is an extremely complex phenomenon comprising a large variety of features (active,region phenomena) in the photosphere, chromosphere and corona. The occurrence of the various active phenomena depends on the phase and state of evolution of the AR; their appearance depends on the radiation used for the observation. The various phenomena are described and illustrated with photographs. Several paragraphs are dedicated to magnetic classification of AR, Mt. Wilson Spot Classification, solar activity indices, and solar activity data publications

  17. Regional projections of nuclear and fossil electric power generation costs

    International Nuclear Information System (INIS)

    Smolen, G.R.; Delene, J.G.; Fuller, L.C.; Bowers, H.I.

    1983-12-01

    The total busbar electric generating costs were estimated for locations in ten regions of the United States for base load nuclear and coal-fired power plants with a startup date of January 1995. A complete data set is supplied which specifies each parameter used to obtain the comparative results. When the comparison is based on reference cost parameters, nuclear- and coal-fired generation costs are found to be very close in most regions of the country. Nuclear power is favored in the South Atlantic region where coal must be transported over long distances, while coal-fired generation is favored in the Central and North Central regions where large reserves of cheaply mineable coal exist. The reference data set reflects recent electric utility construction experience. Significantly lower nuclear capital investment costs would result if regulatory reform and improved construction practices were instituted. The electric power generation costs for base load oil- and natural gas-fired plants were also estimated. These plants were found to be noncompetitive in all regions for those scenarios most likely to develop. Generation cost sensitivity to changes in various parameters was examined at a reference location. The sensitivity parameters included capital investment costs, lead times, capacity factors, costs of money, and coal and uranium prices. In addition to the levelized lifetime costs, year-by-year cash flows and revenue requirements are presented. The report concludes with an analysis of the economic merits of recycling spent fuel in light-water reactors

  18. Institutional Analysis of Knowledge Generation Resource Potential at the Enterprises of Regional Military-Industrial Complex

    Directory of Open Access Journals (Sweden)

    Evgeny Vasilyevich Popov

    2016-09-01

    Full Text Available The article is devoted to the processes of knowledge generation at the enterprises of military-industrial complex, which are the leaders of the regional innovative activity. The target of the research is to develop the methodology based on the use of resource application potential for increasing the efficiency of knowledge generation at the instrument-making enterprises of military-industrial complex. The system analysis of the knowledge generation processes is conducted at one of them. It allows to draw a conclusion that such enterprises have a lack of the institutes of knowledge generation processes. The authors are offered a technique of the development of the knowledge generation system at the military-industrial enterprises based on the accounting of assets and opportunities of the enterprise in the realization of intellectual activity. The developed technique is based on the determination of the horizontal resource potential of knowledge generation and allows to determine the potential of resource application at each stage of product life cycle. The comparison of the actual and theoretical values of horizontal resource potential allows to correct the distribution of a share of each of resources within a stage, and therefore, to optimize the realization of tasks at a specific stage. The offered tools were implemented in 2015 at one of the regional military-Industrial enterprises. The methodological tools of the research include the methods of expert assessment, mathematical statistics and the institutional analysis. On the basis of the offered technique and received empirical results, the institutional spiral of knowledge generation during the filling of state order at the military-industrial enterprise is developed. Its implementation will promote the decrease in the level of uncertainty during the whole life cycle of innovative activity product. The developed institutional spiral of knowledge generation at instrument-making military

  19. Birth and development of active region and chromospheric network

    Energy Technology Data Exchange (ETDEWEB)

    Kartashova, L G

    1975-01-01

    Formation and development of 15 active regions of a simple bipolar configuration with small-sized spots and without noticeable penumbras have been studied by the data of observations with a coronograph CA n the centre and wings of the Hsub(a) line. Resolution on the photographs is 2''. The following conclusions have been drawn: first bright details of the active region formed are generated through brightening of bright points of the chromosphere grid; intensification and stretching of dark points of the chromosphere grid results in the formation of fibrous structure in the vicinity of active region; spots appear either between the flocculi points, or near them closer to the centre of the corresponding cell of the chromosphere grid, among dark points of the chromosphere grid no spots are usually formed; in the process of growing of a simple bipolar group the leader and tail spots draw apart together with the chromosphere grid cells, in which they are formed; at the stage of fast growth in the neighbourhood of most large of the groups under studies a formation of arcs or of almost closed contours of the chromosphere grid is observed in the wings of the line. This rearrangement of the chromosphere grid is apparently closely connected with the formation of a fibrous structure around the active region.

  20. Neural substrates of semantic relationships: common and distinct left-frontal activities for generation of synonyms vs. antonyms.

    Science.gov (United States)

    Jeon, Hyeon-Ae; Lee, Kyoung-Min; Kim, Young-Bo; Cho, Zang-Hee

    2009-11-01

    Synonymous and antonymous relationships among words may reflect the organization and/or processing in the mental lexicon and its implementation in the brain. In this study, functional magnetic resonance imaging (fMRI) is employed to compare brain activities during generation of synonyms (SYN) and antonyms (ANT) prompted by the same words. Both SYN and ANT, when compared with reading nonwords (NW), activated a region in the left middle frontal gyrus (BA 46). Neighboring this region, there was a dissociation observed in that the ANT activation extended more anteriorly and laterally to the SYN activation. The activations in the left middle frontal gyrus may be related to mental processes that are shared in the SYN and ANT generations, such as engaging semantically related parts of mental lexicon for the word search, whereas the distinct activations unique for either SYN or ANT generation may reflect the additional component of antonym retrieval, namely, reversing the polarity of semantic relationship in one crucial dimension. These findings suggest that specific components in the semantic processing, such as the polarity reversal for antonym generation and the similarity assessment for synonyms, are separately and systematically laid out in the left-frontal cortex.

  1. Open magnetic fields in active regions

    Science.gov (United States)

    Svestka, Z.; Solodyna, C. V.; Howard, R.; Levine, R. H.

    1977-01-01

    Soft X-ray images and magnetograms of several active regions and coronal holes are examined which support the interpretation that some of the dark X-ray gaps seen between interconnecting loops and inner cores of active regions are foot points of open field lines inside the active regions. Characteristics of the investigated dark gaps are summarized. All the active regions with dark X-ray gaps at the proper place and with the correct polarity predicted by global potential extrapolation of photospheric magnetic fields are shown to be old active regions, indicating that field opening is accomplished only in a late phase of active-region development. It is noted that some of the observed dark gaps probably have nothing in common with open fields, but are either due to the decreased temperature in low-lying portions of interconnecting loops or are the roots of higher and less dense or cooler loops.

  2. Regional impacts of expanding gas-fired electric generation in the Northeast U.S. and Eastern Canada

    International Nuclear Information System (INIS)

    Mitchell, G.K.

    2001-01-01

    For the purpose of this presentation, the author placed emphasis on the northeast United States, including New York, New England, plus Ontario, Quebec and the Maritime provinces in Canada. The entire region comes under the Northeast Power Coordinating Committee (NPCC) of the North American Electric Reliability Council (NERC). The objective of this Council is to assist with the coordination of electric supply as well as transmission planning and reliability of the utilities. The annual ten year forecast of electric supply, demand and fuel sources produced by the NERC formed the basis for the data presented. The deregulation of the electricity market in a few jurisdictions in the region resulted in the break-up of several electric utilities into their core components: generation, distribution and transmission. The generation sector is where the fastest break-up activity is taking place and merchant energy companies are emerging. Each of these merchant energy companies is competing against the other to effect sales into the wholesale power market through the building of at risk generation plants. The deregulation process is subjected to different processes and time tables depending on each state or provincial regulations. The construction of new power plants in the region is being driven by the merchant energy companies. They are building low capital cost and highly efficient natural gas combined-cycle base load plants as well as lower cost and moderately efficient natural gas/oil-fired simple-cycle peaking plants. This activity is mainly restricted to the United States, since hydroelectric power, coal and nuclear power are the main presence in Canada. New England experiences summer peaks while Canada has winter peak electric demand. To optimize intra-regional peak generation capacity sharing, there is an opportunity for the electric industry to move gas by wire, and a number of projects are being developed. It is expected that pipeline expansion will be lower in

  3. Regional impacts of expanding gas-fired electric generation in the northeast US and eastern Canada

    International Nuclear Information System (INIS)

    Mitchell, G.

    2002-01-01

    New York, New England, Ontario, Quebec and Canada's Maritime provinces come under the jurisdiction of the Northeast Power Coordinating Committee (NPCC) of the North American Electric Reliability Council (NERC). The objective of this Council is to assist with the coordination of electric supply, as well as transmission planning and reliability for the utilities. The annual ten year forecast of electric supply, demand and fuel sources produced by the NERC formed the basis for the data presented. The deregulation of the electricity market in a few jurisdictions in the region resulted in the break-up of several electric utilities into their core components, namely, generation, distribution and transmission. The generation sector is where the fastest break-up activity is taking place, and merchant energy companies are emerging. Each of these merchant energy companies is competing against the other to effect sales into the wholesale power market through the building of at risk generation plants. The deregulation process is subjected to different processes and time tables depending on each state or province regulations. The construction of new power plants in the region is being driven by the merchant energy companies. They are building low capital cost and highly efficient natural gas combined-cycle base load plants as well as lower cost and moderately efficient natural gas/oil-fired simple-cycle peaking plants. This activity is mainly restricted to the United States, since hydroelectric power, coal and nuclear power are the main presence in Canada. New England experiences summer peaks while Canada has winter peak electric demand. To optimize intra-regional peak generation capacity sharing, there is an opportunity for the electric industry to move gas by wire, and a number of projects are being developed. It is expected that pipeline expansion will be lower in Quebec and Ontario and result in more capacity expansions from the Maritimes combined with intra-regional

  4. Spanish Young Generation (JJNN) Activities

    International Nuclear Information System (INIS)

    Millan, Miguel

    2008-01-01

    Spanish Young Generation has been very active during 2006-2008. JJNN have mainly focused on communication activities, as conferences at universities, schools and nuclear companies. Lately, becoming in referent of the young politics, journalist and the young people in Nuclear Subjects is the new and most challenging target of the Spanish Young Generation. In order to accomplish with their objects and commitments with their members, JJNN are developing all kinds of activities focused in the young people and the JJNN members. (authors)

  5. Spanish Young Generation (JJNN) Activities

    Energy Technology Data Exchange (ETDEWEB)

    Millan, Miguel [INITEC Nuclear- Westinghouse, Padilla 17, 28006 Madrid (Spain)

    2008-07-01

    Spanish Young Generation has been very active during 2006-2008. JJNN have mainly focused on communication activities, as conferences at universities, schools and nuclear companies. Lately, becoming in referent of the young politics, journalist and the young people in Nuclear Subjects is the new and most challenging target of the Spanish Young Generation. In order to accomplish with their objects and commitments with their members, JJNN are developing all kinds of activities focused in the young people and the JJNN members. (authors)

  6. The air quality and regional climate effects of widespread solar power generation under a changing regulatory environment

    Science.gov (United States)

    Millstein, D.; Zhai, P.; Menon, S.

    2011-12-01

    Over the past decade significant reductions of NOx and SOx emissions from coal burning power plants in the U.S. have been achieved due to regulatory action and substitution of new generation towards natural gas and wind power. Low natural gas prices, ever decreasing solar generation costs, and proposed regulatory changes, such as to the Cross State Air Pollution Rule, promise further long-run coal power plant emission reductions. Reduced power plant emissions have the potential to affect ozone and particulate air quality and influence regional climate through aerosol cloud interactions and visibility effects. Here we investigate, on a national scale, the effects on future (~2030) air quality and regional climate of power plant emission regulations in contrast to and combination with policies designed to aggressively promote solar electricity generation. A sophisticated, economic and engineering based, hourly power generation dispatch model is developed to explore the integration of significant solar generation resources (>10% on an energy basis) at various regions across the county, providing detailed estimates of substitution of solar generation for fossil fuel generation resources. Future air pollutant emissions from all sectors of the economy are scaled based on the U.S. Environmental Protection Agency's National Emission Inventory to account for activity changes based on population and economic projections derived from county level U.S. Census data and the Energy Information Administration's Annual Energy Outlook. Further adjustments are made for technological and regulatory changes applicable within various sectors, for example, emission intensity adjustments to on-road diesel trucking due to exhaust treatment and improved engine design. The future year 2030 is selected for the emissions scenarios to allow for the development of significant solar generation resources. A regional climate and air quality model (Weather Research and Forecasting, WRF model) is

  7. Generation of auroral kilometric radiation and the structure of auroral acceleration region

    International Nuclear Information System (INIS)

    Lee, L.C.; Kan, J.R.; Wu, C.S.

    1980-01-01

    Generation of auroral kilometric radiation (AKR) in the auroral acceleration region is studied. It is shown that auroral kilometric radiation can be generated by the backscattered electrons trapped in the acceleration region via a cyclotron maser process. The parallel electric field in the acceleration region is required to be distributed over 1-2 Rsub(E). The observed AKR frequency spectrum can be used to estimate the altitude range of the auroral acceleration region. The altitudes of the lower and upper boundaries of the acceleration region determined from the AKR data are respectively approximately 2000 and approximately 9000 km. (author)

  8. Recurrent Forbush decreases and relationship between active regions and M-regions

    International Nuclear Information System (INIS)

    Shah, G.N.; Kaul, C.L.; Razdan, H.; Bemalkhedkar, M.M.

    1977-01-01

    Recurrent Forbush decreases and recurrent geomagnetic disturbances have been attributed to the solar M-regions, which are sources of high velocity solar plasma streams. A study of recurrent Forbush decreases for the period 1966-75 has been made to examine any possible relationship of M-regions with solar active regions. It is shown that at the onset of the recurrent Forbush decrease at earth, there is a high probability of encountering a class of active regions at central meridian of the sun which give rise to flares of importance >= 28/3N. These active regions are found to be long-lasting and to have large areas as well as high Hsub(α)-intensities. Other active regions, producing flares of only lower importance, are distributed randomly on the sun with respect to the onset of a recurrent Forbush decrease. Using the quasiradial hypervelocity approximation, the base of the leading edge of the high velocity stream, at the onset of a recurrent Forbush decrease at earth, is traced to the solar longitude about 40 deg West of the central meridian. From these results, it is deduced that M-regions are located preferentially to the West of long-lasting, magnetically complex active regions. Earlier studies of the identification of the M-regions on the sun have been re-examined and shown to conform to this positional relationship. A possible mechanism of the development of an M-region to the West of the long-lasting magnetically complex active region is also discussed. (author)

  9. Brain regional networks active during the mismatch negativity vary with paradigm.

    Science.gov (United States)

    MacLean, Shannon E; Blundon, Elizabeth G; Ward, Lawrence M

    2015-08-01

    We used independent component analysis (ICA) of high-density EEG recordings coupled with single dipole fitting to identify the dominant brain regions active during the MMN in two different versions of a passive oddball paradigm: a simple, monotic, frequency-deviant paradigm and a more complex, dichotic, frequency-deviant paradigm with deviants occurring in either ear alone or in both ears at the same time. In both paradigms we found brain regional sources in the temporal and frontal cortices active during the MMN period, consistent with some previous studies. In the simpler paradigm, the scalp-potential variance during the earlier (70-120 ms) MMN was mostly accounted for by a wide array of temporal, frontal, and parietal sources. In the more complex paradigm, however, a generator in the prefrontal cortex accounted for a substantial amount of the variance of the scalp potential during the somewhat later MMN period (120-200 ms). These findings are consistent with a more nuanced view of the MMN and its generators than has been held in the past. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs).

    Science.gov (United States)

    Cutts, Josh; Brookhouser, Nicholas; Brafman, David A

    2016-01-01

    Neural progenitor cells (NPCs) derived from human pluripotent stem cells (hPSCs) are a multipotent cell population capable of long-term expansion and differentiation into a variety of neuronal subtypes. As such, NPCs have tremendous potential for disease modeling, drug screening, and regenerative medicine. Current methods for the generation of NPCs results in cell populations homogenous for pan-neural markers such as SOX1 and SOX2 but heterogeneous with respect to regional identity. In order to use NPCs and their neuronal derivatives to investigate mechanisms of neurological disorders and develop more physiologically relevant disease models, methods for generation of regionally specific NPCs and neurons are needed. Here, we describe a protocol in which exogenous manipulation of WNT signaling, through either activation or inhibition, during neural differentiation of hPSCs, promotes the formation of regionally homogenous NPCs and neuronal cultures. In addition, we provide methods to monitor and characterize the efficiency of hPSC differentiation to these regionally specific cell identities.

  11. Cortical regions involved in the generation of musical structures during improvisation in pianists.

    Science.gov (United States)

    Bengtsson, Sara L; Csíkszentmihályi, Mihály; Ullén, Fredrik

    2007-05-01

    Studies on simple pseudorandom motor and cognitive tasks have shown that the dorsolateral prefrontal cortex and rostral premotor areas are involved in free response selection. We used functional magnetic resonance imaging to investigate whether these brain regions are also involved in free generation of responses in a more complex creative behavior: musical improvisation. Eleven professional pianists participated in the study. In one condition, Improvise, the pianist improvised on the basis of a visually displayed melody. In the control condition, Reproduce, the participant reproduced his previous improvisation from memory. Participants were able to reproduce their improvisations with a high level of accuracy, and the contrast Improvise versus Reproduce was thus essentially matched in terms of motor output and sensory feedback. However, the Improvise condition required storage in memory of the improvisation. We therefore also included a condition FreeImp, where the pianist improvised but was instructed not to memorize his performance. To locate brain regions involved in musical creation, we investigated the activations in the Improvise-Reproduce contrast that were also present in FreeImp contrasted with a baseline rest condition. Activated brain regions included the right dorsolateral prefrontal cortex, the presupplementary motor area, the rostral portion of the dorsal premotor cortex, and the left posterior part of the superior temporal gyrus. We suggest that these regions are part of a network involved in musical creation, and discuss their possible functional roles.

  12. Numerical Analysis of Flow Field in Generator End-Winding Region

    Directory of Open Access Journals (Sweden)

    Wei Tong

    2008-01-01

    Full Text Available Cooling in an end-winding region of a high-powered, large-sized generator still remains a challenge today because of a number of factors: a larger number of parts/components with irregular geometries, complexity in cooling flow paths, flow splitting and mixing, and interactions between rotor-induced rotating flows and nonrotating flows from stationary sections. One of the key challenges is to model cooling flows passing through armature bars, which are made up of bundles of strands of insulated copper wires and are bent oppositely to cross each other. This work succeeded in modeling a complex generator end-winding region with great efforts to simplify the model by treating the armature bar region as a porous medium. The flow and pressure fields at the end-winding region were investigated numerically using an axial symmetric computational fluid dynamics (CFD model. Based on the analysis, the cooling flow rate at each flow branch (rotor-stator gap, rotor subslot, outside space block, and small ventilation holes to the heat exchanger was determined, and the high-pressure gradient zones were identified. The CFD results have been successfully used to optimize the flow path configuration for improving the generator operation performance, and the control of the cooling flow, as well as minimizing windage losses and flow-introduced noises.

  13. Nuclear power generation development and the people of the regional community concerned

    International Nuclear Information System (INIS)

    Anzai, Ikuro

    1978-01-01

    Though the nuclear power generation in Japan is planned to be developed with light water reactor power plants as its main stations, regional campaigns against their locations are nowadays evolved in various ways around the sites. In some regions, the problem has been carried into the court in the form of administrative litigation in which the revocation of permission for sites is demanded. Regional campaigns, though different depending upon the regional communities in the people taking leading parts in their activities, have been developed respectively, primarily beginning at simple questions and experiencing the meetings with the authorities concerned and related persons in electric power companies, and the occurrence of abnormalities and failures and the attitudes of persons concerned. It was in 1972 that the Japan Scientist Association proposed six criteria to check up the conditions of nuclear power development in Japan. It further has emphasized that security is to be watched from three points of view. At present, the problems are apt to be grasped as the public nuisance to the people of regional communities. However, in the author's opinion, it is important to recognize the problems essentially as political and economic ones in the global concern or the world history. In the latter half of the article, regional campaigns in various places in Japan are reported in detail. (Wakatsuki, Y.)

  14. Recurrent forbush decreases and the relationship between active regions and M regions

    International Nuclear Information System (INIS)

    Shah, G.N.; Kaul, C.L.; Razdan, H.; Bemalkhedkar, M.M.

    1978-01-01

    Recurrent Forbush decreases and recurrent geomagnetic disturbances have been attributed to the solar M regions, which are sources of high-velocity solar plasma streams. A study of recurrent Forbush decreases for the period 1966--1975 has been made to examine any possible relationship of M regions with solar active regions. It is shown that at the onset of the recurrent Forbush decrease at the earth there is a high probability of encountering a class of active regions at the central meridian of the sun which give rise to flares of importance > or =2B/3N. These active regions are found to be long lasting and to have large areas as well as high Hα intensities. Other active regions, producing flares of lower importance, are distributed randomly on the sun with respect to the onset of a recurrent Forbush decrease. By using the quasi-radial hypervelocity approximation the base of the leading edge of the high-velocity stream at the onset of a recurrent Forbush decrease at the earth is traced to the solar longitude about 40 0 west of the central meridan. From these results it is deduced that M regions are located preferentially to the west of long-lasting magnetically complex active regions. Earlier studies of the identification of the M regions on the sun have been reexamined and shown to conform to this positional relationship. A possible mechanism of the development of an M region to the west of the long-lasting magnetically complex active region is also discussed

  15. Image patch analysis of sunspots and active regions

    Directory of Open Access Journals (Sweden)

    Moon Kevin R.

    2016-01-01

    Full Text Available Context. Separating active regions that are quiet from potentially eruptive ones is a key issue in Space Weather applications. Traditional classification schemes such as Mount Wilson and McIntosh have been effective in relating an active region large scale magnetic configuration to its ability to produce eruptive events. However, their qualitative nature prevents systematic studies of an active region’s evolution for example. Aims. We introduce a new clustering of active regions that is based on the local geometry observed in Line of Sight magnetogram and continuum images. Methods. We use a reduced-dimension representation of an active region that is obtained by factoring the corresponding data matrix comprised of local image patches. Two factorizations can be compared via the definition of appropriate metrics on the resulting factors. The distances obtained from these metrics are then used to cluster the active regions. Results. We find that these metrics result in natural clusterings of active regions. The clusterings are related to large scale descriptors of an active region such as its size, its local magnetic field distribution, and its complexity as measured by the Mount Wilson classification scheme. We also find that including data focused on the neutral line of an active region can result in an increased correspondence between our clustering results and other active region descriptors such as the Mount Wilson classifications and the R-value. Conclusions. Matrix factorization of image patches is a promising new way of characterizing active regions. We provide some recommendations for which metrics, matrix factorization techniques, and regions of interest to use to study active regions.

  16. Dynamic cluster generation for a fuzzy classifier with ellipsoidal regions.

    Science.gov (United States)

    Abe, S

    1998-01-01

    In this paper, we discuss a fuzzy classifier with ellipsoidal regions that dynamically generates clusters. First, for the data belonging to a class we define a fuzzy rule with an ellipsoidal region. Namely, using the training data for each class, we calculate the center and the covariance matrix of the ellipsoidal region for the class. Then we tune the fuzzy rules, i.e., the slopes of the membership functions, successively until there is no improvement in the recognition rate of the training data. Then if the number of the data belonging to a class that are misclassified into another class exceeds a prescribed number, we define a new cluster to which those data belong and the associated fuzzy rule. Then we tune the newly defined fuzzy rules in the similar way as stated above, fixing the already obtained fuzzy rules. We iterate generation of clusters and tuning of the newly generated fuzzy rules until the number of the data belonging to a class that are misclassified into another class does not exceed the prescribed number. We evaluate our method using thyroid data, Japanese Hiragana data of vehicle license plates, and blood cell data. By dynamic cluster generation, the generalization ability of the classifier is improved and the recognition rate of the fuzzy classifier for the test data is the best among the neural network classifiers and other fuzzy classifiers if there are no discrete input variables.

  17. NON-NEUTRALIZED ELECTRIC CURRENT PATTERNS IN SOLAR ACTIVE REGIONS: ORIGIN OF THE SHEAR-GENERATING LORENTZ FORCE

    International Nuclear Information System (INIS)

    Georgoulis, Manolis K.; Titov, Viacheslav S.; Mikić, Zoran

    2012-01-01

    Using solar vector magnetograms of the highest available spatial resolution and signal-to-noise ratio, we perform a detailed study of electric current patterns in two solar active regions (ARs): a flaring/eruptive and a flare-quiet one. We aim to determine whether ARs inject non-neutralized (net) electric currents in the solar atmosphere, responding to a debate initiated nearly two decades ago that remains inconclusive. We find that well-formed, intense magnetic polarity inversion lines (PILs) within ARs are the only photospheric magnetic structures that support significant net current. More intense PILs seem to imply stronger non-neutralized current patterns per polarity. This finding revises previous works that claim frequent injections of intense non-neutralized currents by most ARs appearing in the solar disk but also works that altogether rule out injection of non-neutralized currents. In agreement with previous studies, we also find that magnetically isolated ARs remain globally current-balanced. In addition, we confirm and quantify the preference of a given magnetic polarity to follow a given sense of electric currents, indicating a dominant sense of twist in ARs. This coherence effect is more pronounced in more compact ARs with stronger PILs and must be of sub-photospheric origin. Our results yield a natural explanation of the Lorentz force, invariably generating velocity and magnetic shear along strong PILs, thus setting a physical context for the observed pre-eruption evolution in solar ARs.

  18. The era of the wandering mind? Twenty-first century research on self-generated mental activity

    Directory of Open Access Journals (Sweden)

    Felicity eCallard

    2013-12-01

    Full Text Available The first decade of the twenty-first century was characterized by renewed scientific interest in self-generated mental activity (activity largely generated by the individual, rather than in response to experimenters’ instructions or specific external sensory inputs. To understand this renewal of interest, we interrogated the peer-reviewed literature from 2003–2012 (i to explore recent changes in use of terms for self-generated mental activity; (ii to investigate changes in the topics on which mind wandering research, specifically, focuses; and (iii to visualize co-citation communities amongst researchers working on self-generated mental activity. Our analyses demonstrated that there has been a dramatic increase in the term mind wandering, and a significant crossing-over of psychological investigations of mind wandering, specifically, into cognitive neuroscience. If this is, indeed, the ‘era of the wandering mind’, our paper calls for more explicit reflection to be given by mind wandering researchers to the terms they use, the topics and brain regions they focused on, and the research literatures that they implicitly foreground or ignore as not relevant.

  19. Prediction of household and commercial BMW generation according to socio-economic and other factors for the Dublin region.

    Science.gov (United States)

    Purcell, M; Magette, W L

    2009-04-01

    Both planning and design of integrated municipal solid waste management systems require accurate prediction of waste generation. This research predicted the quantity and distribution of biodegradable municipal waste (BMW) generation within a diverse 'landscape' of residential areas, as well as from a variety of commercial establishments (restaurants, hotels, hospitals, etc.) in the Dublin (Ireland) region. Socio-economic variables, housing types, and the sizes and main activities of commercial establishments were hypothesized as the key determinants contributing to the spatial variability of BMW generation. A geographical information system (GIS) 'model' of BMW generation was created using ArcMap, a component of ArcGIS 9. Statistical data including socio-economic status and household size were mapped on an electoral district basis. Historical research and data from scientific literature were used to assign BMW generation rates to residential and commercial establishments. These predictions were combined to give overall BMW estimates for the region, which can aid waste planning and policy decisions. This technique will also aid the design of future waste management strategies, leading to policy and practice alterations as a function of demographic changes and development. The household prediction technique gave a more accurate overall estimate of household waste generation than did the social class technique. Both techniques produced estimates that differed from the reported local authority data; however, given that local authority reported figures for the region are below the national average, with some of the waste generated from apartment complexes being reported as commercial waste, predictions arising from this research are believed to be closer to actual waste generation than a comparison to reported data would suggest. By changing the input data, this estimation tool can be adapted for use in other locations. Although focusing on waste in the Dublin region

  20. Decentralized electricity generation from renewable sources as a chance for local economic development. A qualitative study of two pioneer regions in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Klagge, Britta; Brocke, Tobias [Osnabrueck Univ. (Germany). Inst. of Geography

    2012-12-15

    Empirical research on the local economic effects associated with decentralized electricity generation from renewable sources has only just started. So far, most studies focus on quantifying economic effects and neglect the conditions and constellations which support and enable local economic development based on decentralized electricity generation. This, however, is the focus of this paper which looks at these issues, employing the value chain concept in combination with a governance perspective. Empirically, we take a qualitative approach and analyze two case studies of pioneer regions, in which decentralized electricity generation from renewable sources has developed very dynamically. The case study regions are Soltau, with a special focus on biogas production, and Emden, where wind energy plays a special role. Based on the early activities of some pioneers, these regions have developed specific actor constellations and organizational structures and have entered development paths in which renewable energies became an important economic factor. The analysis highlights the importance of institutional context and supportive governance structures for an early advancement of decentralized electricity generation from renewable sources, with a key role of local actors and governance constellations. It also points to the importance of cooperative relationships among local business actors for creating a competitive advantage for (some) regional firms. Our analysis shows that with the geographical proliferation of electricity generation from renewable sources, specialized firms tend to reach beyond their regions, thus offering first-mover advantages for firms in pioneer regions in comparison with latecomers.

  1. Open magnetic fields in active regions

    International Nuclear Information System (INIS)

    Svestka, Z.; Solodyna, C.V.; Levine, R.H.

    1977-01-01

    Soft X-ray observations confirm that some of the dark gaps seen between interconnecting loops and inner cores of active regions may be loci of open fields, as it has been predicted by global potential extrapolation of photospheric magnetic fields. It seems that the field lines may open only in a later state of the active region development. (Auth.)

  2. The Limit of Free Magnetic Energy in Active Regions

    Science.gov (United States)

    Moore, Ron; Falconer, David; Sterling, Alphonse

    2012-01-01

    By measuring from active-region magnetograms a proxy of the free energy in the active region fs magnetic field, it has been found previously that (1) there is an abrupt upper limit to the free energy the field can hold that increases with the amount of magnetic field in the active region, the active region fs magnetic flux content, and (2) the free energy is usually near its limit when the field explodes in a CME/flare eruption. That is, explosive active regions are concentrated in a main-sequence path bordering the free-energy ]limit line in (flux content, free-energy proxy) phase space. Here, from measurement of Marshall Space Flight Center vector magnetograms, we find the magnetic condition that underlies the free ]energy limit and the accompanying main sequence of explosive active regions. Using a suitable free ]energy proxy measured from vector magnetograms of 44 active regions, we find that (1) in active regions at and near their free ]energy limit, the ratio of magnetic-shear free energy to the non ]free magnetic energy the potential field would have is approximately 1 in the core field, the field rooted along the neutral line, and (2) this ratio is progressively less in active regions progressively farther below their free ]energy limit. This shows that most active regions in which this core-field energy ratio is much less than 1 cannot be triggered to explode; as this ratio approaches 1, most active regions become capable of exploding; and when this ratio is 1 or greater, most active regions are compelled to explode. From these results we surmise the magnetic condition that determines the free ]energy limit is the ratio of the free magnetic energy to the non-free energy the active region fs field would have were it completely relaxed to its potential ]field configuration, and that this ratio is approximately 1 at the free-energy limit and in the main sequence of explosive active regions.

  3. Phosalone-Induced Changes in Regional Cholinesterase Activities ...

    African Journals Online (AJOL)

    ... in Regional Cholinesterase Activities in Rat Brain during Behavioral Tolerance. ... lead to the gradual disappearance of the initial signs of toxicity over time, termed ... regions, striatum recorded a greater decrease in cholinesterase activity.

  4. Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study

    DEFF Research Database (Denmark)

    Kjaerulff, O; Kiehn, O

    1996-01-01

    The isolated spinal cord of the newborn rat contains networks that are able to create a patterned motor output resembling normal locomotor movements. In this study, we sought to localize the regions of primary importance for rhythm and pattern generation using specific mechanical lesions. We used...... ventral root recordings to monitor neuronal activity and tested the ability of various isolated parts of the caudal thoraciclumbar cord to generate rhythmic bursting in a combination of 5-HT and NMDA. In addition, pathways mediating left/right and rostrocaudal burst alternation were localized. We found......, these pathways were distributed along the lumbar enlargement. Both lateral and ventral funiculi were sufficient to coordinate activity in the rostral and caudal regions. We conclude that the networks organizing locomotor-related activity in the spinal cord of the newborn rat are distributed....

  5. A Survey of Municipal Solid Waste Generation in 22 Regions of Tehran With Solid Waste Reduction Approach

    Directory of Open Access Journals (Sweden)

    MA Abduli

    2015-07-01

    Methods: The study was a descriptive cross-sectional one conducted from 2010 to 2014. Relevant officials of the waste recovery in 22 regions of Tehran were approached in order to collect data about municipal solid waste generation through interviewing, filling out questionnaires, conducting field visits from Aradkooh Disposal and Processing Complex and collecting information on disposal and destiny of wastes. Then the data were compiled and analyzed. Results: Total solid waste generation in Tehran from 2010 to 2014 amounted to respectively 3389662, 3399344, 3449338 and 3245157 Metric Tons, categorized into three groups of municipal, companies and townships and hospital wastes. Most of the generated waste produced in Tehran was that of households and commercial (known as municipal waste from 22 Regions of Tehran. Based on the surveys conducted, per capita solid waste generation of 11 regions of Tehran ranged from 550 to 1000 grams and in other 11 ones from 1000 to 1521 grams per capita per day. The lowest and highest waste generation rate belonged respectively to region 13 with 556 grams and region 12 with 1521 grams per capita per day in 2011. Conclusion: Comparing per capita generation of municipal solid waste in different municipal regions in Tehran with maximum acceptable capacity of waste generation indicates the deviation of waste generation of all Tehran regions from the standard acceptable amount. Therefore, not only is it necessary to plan and take strategic measures to reduce Tehran waste generation but also these programs and measures should be specific to each region considering its specifications and solid waste quality and quantity.

  6. Macroeconomic dataset for generating macroeconomic volatility among selected countries in the Asia Pacific region

    OpenAIRE

    Chow, Yee Peng; Muhammad, Junaina; Amin Noordin, Bany Ariffin; Cheng, Fan Fah

    2017-01-01

    This data article provides macroeconomic data that can be used to generate macroeconomic volatility. The data cover a sample of seven selected countries in the Asia Pacific region for the period 2004–2014, including both developing and developed countries. This dataset was generated to enhance our understanding of the sources of macroeconomic volatility affecting the countries in this region. Although the Asia Pacific region continues to remain as the most dynamic part of the world's economy,...

  7. [Do regional and generational differences in attitudes toward "Luck Resource Belief" exist?].

    Science.gov (United States)

    Murakami, Koshi

    2016-04-01

    This article examines whether belief in superstitions and folklore differs by age and degree of modernization specifically. This study investigated regional and generational differences in attitudes toward "Luck Resource Belief," a notion regarding luck. The 500 Japanese participants in our sample were stratified by place of residence, age, and income. The results reflected gender differences, but not regional or generational differences with regard to the "Luck Resource Belief" scale scores. Based on these results, the hypothesis that the mass media plays a major role in the dissemination of information about superstitions and folklore is discussed in this context.

  8. Regional Brain Activation during Meditation Shows Time and Practice Effects: An Exploratory FMRI Study

    Directory of Open Access Journals (Sweden)

    E. Baron Short

    2010-01-01

    Full Text Available Meditation involves attentional regulation and may lead to increased activity in brain regions associated with attention such as dorsal lateral prefrontal cortex (DLPFC and anterior cingulate cortex (ACC. Using functional magnetic resonance imaging, we examined whether DLPFC and ACC were activated during meditation. Subjects who meditate were recruited and scanned on a 3.0 Tesla scanner. Subjects meditated for four sessions of 12 min and performed four sessions of a 6 min control task. Individual and group t-maps were generated of overall meditation response versus control response and late meditation response versus early meditation response for each subject and time courses were plotted. For the overall group (n = 13, and using an overall brain analysis, there were no statistically significant regional activations of interest using conservative thresholds. A region of interest analysis of the entire group time courses of DLPFC and ACC were statistically more active throughout meditation in comparison to the control task. Moreover, dividing the cohort into short (n = 8 and long-term (n = 5 practitioners (>10 years revealed that the time courses of long-term practitioners had significantly more consistent and sustained activation in the DLPFC and the ACC during meditation versus control in comparison to short-term practitioners. The regional brain activations in the more practised subjects may correlate with better sustained attention and attentional error monitoring. In summary, brain regions associated with attention vary over the time of a meditation session and may differ between long- and short-term meditation practitioners.

  9. Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions

    Directory of Open Access Journals (Sweden)

    Agnete Kirkeby

    2012-06-01

    Full Text Available To model human neural-cell-fate specification and to provide cells for regenerative therapies, we have developed a method to generate human neural progenitors and neurons from human embryonic stem cells, which recapitulates human fetal brain development. Through the addition of a small molecule that activates canonical WNT signaling, we induced rapid and efficient dose-dependent specification of regionally defined neural progenitors ranging from telencephalic forebrain to posterior hindbrain fates. Ten days after initiation of differentiation, the progenitors could be transplanted to the adult rat striatum, where they formed neuron-rich and tumor-free grafts with maintained regional specification. Cells patterned toward a ventral midbrain (VM identity generated a high proportion of authentic dopaminergic neurons after transplantation. The dopamine neurons showed morphology, projection pattern, and protein expression identical to that of human fetal VM cells grafted in parallel. VM-patterned but not forebrain-patterned neurons released dopamine and reversed motor deficits in an animal model of Parkinson's disease.

  10. Representing and estimating interactions between activities in a need-based model of activity generation

    NARCIS (Netherlands)

    Nijland, L.; Arentze, T.; Timmermans, H.

    2013-01-01

    Although several activity-based models made the transition to practice in recent years, modeling dynamic activity generation and especially, the mechanisms underlying activity generation are not well incorporated in the current activity-based models. For instance, current models assume that

  11. Representing and estimating interactions between activities in a need-based model of activity generation

    NARCIS (Netherlands)

    Nijland, E.W.L.; Arentze, T.A.; Timmermans, H.J.P.

    2011-01-01

    Although several activity-based models made the transition to practice in recent years, modelling dynamic activity generation and especially, the mechanisms underlying activity generation are not well incorporated in the current activity-based models. For example, current models assume that

  12. Observations of concentrated generator regions in the nightside magnetosphere by Cluster/FAST conjunctions

    Directory of Open Access Journals (Sweden)

    M. Hamrin

    2006-03-01

    Full Text Available Here and in the companion paper, Marghitu et al. (2006, we investigate plausible auroral generator regions in the nightside auroral magnetosphere. In this article we use magnetically conjugate data from the Cluster and the FAST satellites during a 3.5-h long event from 19-20 September 2001. Cluster is in the Southern Hemisphere close to apogee, where it probes the plasma sheet and lobe at an altitude of about 18 RE. FAST is below the acceleration region at approximately 0.6 RE. Searching for clear signatures of negative power densities, E·J<0, in the Cluster data we can identify three concentrated generator regions (CGRs during our event. From the magnetically conjugate FAST data we see that the observed generator regions in the Cluster data correlate with auroral precipitation. The downward Poynting flux observed by Cluster, as well as the scale size of the CGRs, are consistent with the electron energy flux and the size of the inverted-V regions observed by FAST. To our knowledge, these are the first in-situ observations of the crossing of an auroral generator region. The main contribution to E·J<0 comes from the GSE EyJy. The electric field Ey is weakly negative during most of our entire event and we conclude that the CGRs occur when the duskward current Jy grows large and positive. We find that our observations are consistent with a local southward expansion of the plasma sheet and/or rather complicated, 3-D wavy structures propagating over the Cluster satellites. We find that the plasma is working against the magnetic field, and that kinetic energy is being converted into electromagnetic energy. Some of the energy is transported away as Poynting flux.

  13. Parameters of oscillation generation regions in open star cluster models

    Science.gov (United States)

    Danilov, V. M.; Putkov, S. I.

    2017-07-01

    We determine the masses and radii of central regions of open star cluster (OCL) models with small or zero entropy production and estimate the masses of oscillation generation regions in clustermodels based on the data of the phase-space coordinates of stars. The radii of such regions are close to the core radii of the OCL models. We develop a new method for estimating the total OCL masses based on the cluster core mass, the cluster and cluster core radii, and radial distribution of stars. This method yields estimates of dynamical masses of Pleiades, Praesepe, and M67, which agree well with the estimates of the total masses of the corresponding clusters based on proper motions and spectroscopic data for cluster stars.We construct the spectra and dispersion curves of the oscillations of the field of azimuthal velocities v φ in OCL models. Weak, low-amplitude unstable oscillations of v φ develop in cluster models near the cluster core boundary, and weak damped oscillations of v φ often develop at frequencies close to the frequencies of more powerful oscillations, which may reduce the non-stationarity degree in OCL models. We determine the number and parameters of such oscillations near the cores boundaries of cluster models. Such oscillations points to the possible role that gradient instability near the core of cluster models plays in the decrease of the mass of the oscillation generation regions and production of entropy in the cores of OCL models with massive extended cores.

  14. Regional hospital improves efficiency with co-generation retrofit.

    Science.gov (United States)

    Knutson, D; Anderson, L

    1999-11-01

    Feasibility analysis of the co-generation retrofit of the Red Deer Regional Hospital pointed to a reasonable payback of capital cost and increased efficiency in operation of the facility. Budget restrictions nearly stopped the project from proceeding. Innovative construction procedures proposed by the Facility Management Group, in particular, Mr Keith Metcalfe, Director of Maintenance, allowed a worthwhile project to reach successful completion. We feel that this model can perhaps be used by similar facilities in the future to achieve their energy efficiency goals.

  15. STATISTICAL ANALYSIS OF ACOUSTIC WAVE PARAMETERS NEAR SOLAR ACTIVE REGIONS

    International Nuclear Information System (INIS)

    Rabello-Soares, M. Cristina; Bogart, Richard S.; Scherrer, Philip H.

    2016-01-01

    In order to quantify the influence of magnetic fields on acoustic mode parameters and flows in and around active regions, we analyze the differences in the parameters in magnetically quiet regions nearby an active region (which we call “nearby regions”), compared with those of quiet regions at the same disk locations for which there are no neighboring active regions. We also compare the mode parameters in active regions with those in comparably located quiet regions. Our analysis is based on ring-diagram analysis of all active regions observed by the Helioseismic and Magnetic Imager (HMI) during almost five years. We find that the frequency at which the mode amplitude changes from attenuation to amplification in the quiet nearby regions is around 4.2 mHz, in contrast to the active regions, for which it is about 5.1 mHz. This amplitude enhacement (the “acoustic halo effect”) is as large as that observed in the active regions, and has a very weak dependence on the wave propagation direction. The mode energy difference in nearby regions also changes from a deficit to an excess at around 4.2 mHz, but averages to zero over all modes. The frequency difference in nearby regions increases with increasing frequency until a point at which the frequency shifts turn over sharply, as in active regions. However, this turnover occurs around 4.9 mHz, which is significantly below the acoustic cutoff frequency. Inverting the horizontal flow parameters in the direction of the neigboring active regions, we find flows that are consistent with a model of the thermal energy flow being blocked directly below the active region.

  16. Discharges in the inlet region of a noble gas MHD generator

    International Nuclear Information System (INIS)

    Borghi, C.A.

    1982-01-01

    In this work the onset of the development of the non-equilibrium conductivity in the entrance region of a noble gas MHD generator is investigated both theoretically and experimentally. At low electron densities the discharge seems to be affected by a non-Maxwellian electron distribution. In Chapter II a self-consistent model of a stationary discharge in an Ar-Cs mixture at atmospheric pressure, is set up. It includes the possibility of deviations from a Maxwellian electron energy distribution. The model allows to calculate at what discharge parameters deviations from the Maxwellian electron distribution will become important. In Chapter III the relaxation of the plasma to a new equilibrium situation following a sudden change in the electron thermal energy is calculated by a model which can take radiation and a non-Maxwellian distribution into account. In Chapter IV an Ar-Cs discharge experiment is described with plasma parameters similar to those present in the entrance region of the generator. The ionization relaxation process in a noble gas MHD generator is experimentally studied and described in Chapter V. In this chapter the relaxation ionization region with and without pre-ionization is investigated. Current voltage characteristics are obtained by varying the applied voltage or the external load. The results are confronted with the theoretical results of the non-Maxwellian model developed in Chapter II. Conclusions of this work are drawn in Chapter VI. (Auth.)

  17. Neutronics activities for next generation devices

    International Nuclear Information System (INIS)

    Gohar, Y.

    1985-01-01

    Neutronic activities for the next generation devices are the subject of this paper. The main activities include TFCX and FPD blanket/shield studies, neutronic aspects of ETR/INTOR critical issues, and neutronics computational modules for the tokamak system code and tandem mirror reactor system code. Trade-off analyses, optimization studies, design problem investigations and computational models development for reactor parametric studies carried out for these activities are summarized

  18. Unleashing creativity: The role of left temporoparietal regions in evaluating and inhibiting the generation of creative ideas.

    Science.gov (United States)

    Mayseless, Naama; Aharon-Peretz, Judith; Shamay-Tsoory, Simone

    2014-11-01

    Human creativity is thought to entail two processes. One is idea generation, whereby ideas emerge in an associative manner, and the other is idea evaluation, whereby generated ideas are evaluated and screened. Thus far, neuroimaging studies have identified several brain regions as being involved in creativity, yet only a handful of studies have examined the neural basis underlying these two processes. We found that an individual with left temporoparietal hemorrhage who had no previous experience as an artist developed remarkable artistic creativity, which diminished as the hemorrhage receded. We thus hypothesized that damage to the evaluation network of creativity during the initial hematoma had a releasing effect on creativity by "freeing" the idea generation system. In line with this hypothesis, we conducted a subsequent fMRI study showing that decreased left temporal and parietal activations among healthy individuals as they evaluated creative ideas selectively predicted higher creativity. The current studies provide converging multi-method evidence suggesting that the left temporoparietal area is part of a neural network involved in evaluating creativity, and that as such may act as inhibitors of creativity. We propose an explanatory model of creativity centered upon the key role of the left temporoparietal regions in evaluating and inhibiting creativity. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Short-term forecasting model for aggregated regional hydropower generation

    International Nuclear Information System (INIS)

    Monteiro, Claudio; Ramirez-Rosado, Ignacio J.; Fernandez-Jimenez, L. Alfredo

    2014-01-01

    Highlights: • Original short-term forecasting model for the hourly hydropower generation. • The use of NWP forecasts allows horizons of several days. • New variable to represent the capacity level for generating hydroelectric energy. • The proposed model significantly outperforms the persistence model. - Abstract: This paper presents an original short-term forecasting model of the hourly electric power production for aggregated regional hydropower generation. The inputs of the model are previously recorded values of the aggregated hourly production of hydropower plants and hourly water precipitation forecasts using Numerical Weather Prediction tools, as well as other hourly data (load demand and wind generation). This model is composed of three modules: the first one gives the prediction of the “monthly” hourly power production of the hydropower plants; the second module gives the prediction of hourly power deviation values, which are added to that obtained by the first module to achieve the final forecast of the hourly hydropower generation; the third module allows a periodic adjustment of the prediction of the first module to improve its BIAS error. The model has been applied successfully to the real-life case study of the short-term forecasting of the aggregated hydropower generation in Spain and Portugal (Iberian Peninsula Power System), achieving satisfactory results for the next-day forecasts. The model can be valuable for agents involved in electricity markets and useful for power system operations

  20. Rapid eye movement sleep deprivation induces an increase in acetylcholinesterase activity in discrete rat brain regions

    Directory of Open Access Journals (Sweden)

    Benedito M.A.C.

    2001-01-01

    Full Text Available Some upper brainstem cholinergic neurons (pedunculopontine and laterodorsal tegmental nuclei are involved in the generation of rapid eye movement (REM sleep and project rostrally to the thalamus and caudally to the medulla oblongata. A previous report showed that 96 h of REM sleep deprivation in rats induced an increase in the activity of brainstem acetylcholinesterase (Achase, the enzyme which inactivates acetylcholine (Ach in the synaptic cleft. There was no change in the enzyme's activity in the whole brain and cerebrum. The components of the cholinergic synaptic endings (for example, Achase are not uniformly distributed throughout the discrete regions of the brain. In order to detect possible regional changes we measured Achase activity in several discrete rat brain regions (medulla oblongata, pons, thalamus, striatum, hippocampus and cerebral cortex after 96 h of REM sleep deprivation. Naive adult male Wistar rats were deprived of REM sleep using the flower-pot technique, while control rats were left in their home cages. Total, membrane-bound and soluble Achase activities (nmol of thiocholine formed min-1 mg protein-1 were assayed photometrically. The results (mean ± SD obtained showed a statistically significant (Student t-test increase in total Achase activity in the pons (control: 147.8 ± 12.8, REM sleep-deprived: 169.3 ± 17.4, N = 6 for both groups, P<0.025 and thalamus (control: 167.4 ± 29.0, REM sleep-deprived: 191.9 ± 15.4, N = 6 for both groups, P<0.05. Increases in membrane-bound Achase activity in the pons (control: 171.0 ± 14.7, REM sleep-deprived: 189.5 ± 19.5, N = 6 for both groups, P<0.05 and soluble enzyme activity in the medulla oblongata (control: 147.6 ± 16.3, REM sleep-deprived: 163.8 ± 8.3, N = 6 for both groups, P<0.05 were also observed. There were no statistically significant differences in the enzyme's activity in the other brain regions assayed. The present findings show that the increase in Achase activity

  1. Generating new telehealth services using a whole of community approach: experience in regional Queensland.

    Science.gov (United States)

    Smith, Anthony C; Caffery, Liam J; Saunders, Ruth; Bradford, Natalie K; Gray, Leonard C

    2014-10-01

    We implemented a community telehealth project in the three towns in the Darling Downs area of Queensland over a 2-year period starting in July 2012. The purpose of the project was to generate telehealth activity in hospitals, general practice and selected residential aged care facilities. Telehealth education and training was provided to clinicians in the three towns and a community awareness campaign was delivered using advertisements in newspapers, messages in social media and presentations at community events. A total of 55 stakeholders were engaged with during 61 site visits to health care facilities during the first two years of the project. During the study period, telehealth activity in Queensland increased in the hospital sector by 39% and in the non-hospital sector by 99%. In the Darling Downs region, telehealth activity in the hospital sector increased by 104%, compared to 28% in the rest of Queensland. However, in the non-hospital sector, the increase in telehealth activity in the Darling Downs region was similar to the rest of Queensland. Telehealth services established and/or facilitated by the project included specialist geriatric ward rounds in Dalby, Chinchilla and Miles for patients in the local hospitals and nursing homes; and ad-hoc teleconsultations for children and adults living in these communities, with specialists at Toowoomba and hospitals in Brisbane. An increase in telehealth implies better access to a range of clinical services, which may result in improved clinical outcomes for patients. © The Author(s) 2014 Reprints and permissions:]br]sagepub.co.uk/journalsPermissions.nav.

  2. Emergence of Magnetic Flux Generated in a Solar Convective Dynamo. I. The Formation of Sunspots and Active Regions, and The Origin of Their Asymmetries

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Feng; Rempel, Matthias; Fan, Yuhong, E-mail: chenfeng@ucar.edu [High Altitude Observatory, NCAR, P.O. Box 3000, Boulder, CO, 80307 (United States)

    2017-09-10

    We present a realistic numerical model of sunspot and active region formation based on the emergence of flux bundles generated in a solar convective dynamo. To this end, we use the magnetic and velocity fields in a horizontal layer near the top boundary of the solar convective dynamo simulation to drive realistic radiative-magnetohydrodynamic simulations of the uppermost layers of the convection zone. The main results are as follows. (1) The emerging flux bundles rise with the mean speed of convective upflows and fragment into small-scale magnetic elements that further rise to the photosphere, where bipolar sunspot pairs are formed through the coalescence of the small-scale magnetic elements. (2) Filamentary penumbral structures form when the sunspot is still growing through ongoing flux emergence. In contrast to the classical Evershed effect, the inflow seems to prevail over the outflow in a large part of the penumbra. (3) A well-formed sunspot is a mostly monolithic magnetic structure that is anchored in a persistent deep-seated downdraft lane. The flow field outside the spot shows a giant vortex ring that comprises an inflow below 15 Mm depth and an outflow above 15 Mm depth. (4) The sunspots successfully reproduce the fundamental properties of the observed solar active regions, including the more coherent leading spots with a stronger field strength, and the correct tilts of bipolar sunspot pairs. These asymmetries can be linked to the intrinsic asymmetries in the magnetic and flow fields adapted from the convective dynamo simulation.

  3. Observations of concentrated generator regions in the nightside magnetosphere by Cluster/FAST conjunctions

    Directory of Open Access Journals (Sweden)

    M. Hamrin

    2006-03-01

    Full Text Available Here and in the companion paper, Marghitu et al. (2006, we investigate plausible auroral generator regions in the nightside auroral magnetosphere. In this article we use magnetically conjugate data from the Cluster and the FAST satellites during a 3.5-h long event from 19-20 September 2001. Cluster is in the Southern Hemisphere close to apogee, where it probes the plasma sheet and lobe at an altitude of about 18 RE. FAST is below the acceleration region at approximately 0.6 RE. Searching for clear signatures of negative power densities, E·J<0, in the Cluster data we can identify three concentrated generator regions (CGRs during our event. From the magnetically conjugate FAST data we see that the observed generator regions in the Cluster data correlate with auroral precipitation. The downward Poynting flux observed by Cluster, as well as the scale size of the CGRs, are consistent with the electron energy flux and the size of the inverted-V regions observed by FAST. To our knowledge, these are the first in-situ observations of the crossing of an auroral generator region. The main contribution to E·J<0 comes from the GSE EyJy. The electric field Ey is weakly negative during most of our entire event and we conclude that the CGRs occur when the duskward current Jy grows large and positive. We find that our observations are consistent with a local southward expansion of the plasma sheet and/or rather complicated, 3-D wavy structures propagating over the Cluster satellites. We find that the plasma is working against the magnetic field, and that kinetic energy is being converted into electromagnetic energy. Some of the energy is transported away as Poynting flux.

  4. Spot markets vs. long-term contracts - modelling tools for regional electricity generating utilities

    International Nuclear Information System (INIS)

    Grohnheit, P.E.

    1999-01-01

    A properly organised market for electricity requires that some information will be available for all market participants. Also a range of generally available modelling tools are necessary. This paper describes a set of simple models based on published data for analyses of the long-term revenues of regional utilities with combined heat and power generation (CHP), who will operate a competitive international electricity market and a local heat market. The future revenues from trade on the spot market is analysed using a load curve model, in which marginal costs are calculated on the basis of short-term costs of the available units and chronological hourly variations in the demands for electricity and heat. Assumptions on prices, marginal costs and electricity generation by the different types of generating units are studied for selected types of local electricity generators. The long-term revenue requirements to be met by long-term contracts are analysed using a traditional techno-economic optimisation model focusing on technology choice and competition among technologies over 20.30 years. A possible conclusion from this discussion is that it is important for the economic and environmental efficiency of the electricity market that local or regional generators of CHP, who are able to react on price signals, do not conclude long-term contracts that include fixed time-of-day tariff for sale of electricity. Optimisation results for a CHP region (represented by the structure of the Danish electricity and CHP market in 1995) also indicates that a market for CO 2 tradable permits is unlikely to attract major non-fossil fuel technologies for electricity generation, e.g. wind power. (au)

  5. Regional comparison of nuclear and fossil electric power generation costs

    International Nuclear Information System (INIS)

    Bowers, H.I.

    1984-01-01

    Nuclear's main disadvantages are its high capital investment cost and uncertainty in schedule compared with alternatives. Nuclear plant costs continue to rise whereas coal plant investment costs are staying relative steady. Based on average experience, nuclear capital investment costs are nearly double those of coal-fired generation plants. The capital investment cost disadvantage of nuclear is balanced by its fuel cost advantages. New base load nuclear power plants were projected to be competitive with coal-fired plants in most regions of the country. Nuclear power costs wre projected to be significantly less (10% or more) than coal-fired power costs in the South Atlantic region. Coal-fired plants were projected to have a significant economic advantage over nuclear plants in the Central and North Central regions. In the remaining seven regions, the levelized cost of power from either option was projected to be within 10%. Uncertainties in future costs of materials, services, and financing affect the relative economics of the nuclear and coal options significantly. 10 figures

  6. Parkinson-related changes of activation in visuomotor brain regions during perceived forward self-motion.

    Directory of Open Access Journals (Sweden)

    Anouk van der Hoorn

    Full Text Available Radial expanding optic flow is a visual consequence of forward locomotion. Presented on screen, it generates illusionary forward self-motion, pointing at a close vision-gait interrelation. As particularly parkinsonian gait is vulnerable to external stimuli, effects of optic flow on motor-related cerebral circuitry were explored with functional magnetic resonance imaging in healthy controls (HC and patients with Parkinson's disease (PD. Fifteen HC and 22 PD patients, of which 7 experienced freezing of gait (FOG, watched wide-field flow, interruptions by narrowing or deceleration and equivalent control conditions with static dots. Statistical parametric mapping revealed that wide-field flow interruption evoked activation of the (pre-supplementary motor area (SMA in HC, which was decreased in PD. During wide-field flow, dorsal occipito-parietal activations were reduced in PD relative to HC, with stronger functional connectivity between right visual motion area V5, pre-SMA and cerebellum (in PD without FOG. Non-specific 'changes' in stimulus patterns activated dorsolateral fronto-parietal regions and the fusiform gyrus. This attention-associated network was stronger activated in HC than in PD. PD patients thus appeared compromised in recruiting medial frontal regions facilitating internally generated virtual locomotion when visual motion support falls away. Reduced dorsal visual and parietal activations during wide-field optic flow in PD were explained by impaired feedforward visual and visuomotor processing within a magnocellular (visual motion functional chain. Compensation of impaired feedforward processing by distant fronto-cerebellar circuitry in PD is consistent with motor responses to visual motion stimuli being either too strong or too weak. The 'change'-related activations pointed at covert (stimulus-driven attention.

  7. Nonlinear radiation generation processes in the auroral acceleration region

    Directory of Open Access Journals (Sweden)

    R. Pottelette

    2017-11-01

    Full Text Available It is known from laboratory plasma experiments that double layers (DLs radiate in the electromagnetic spectrum; but this is only known qualitatively. In these experiments, it was shown that the electron beam created on the high-potential side of a DL generates nonlinear structures which couple to electromagnetic waves and act as a sender antenna. In the Earth auroral region, observations performed by auroral spacecraft have shown that DLs occur naturally in the source region of intense radio emissions called auroral kilometric radiation (AKR. Very high time-, spatial-, and temporal-resolution measurements are needed in order to characterize waves and particle distributions in the vicinity of DLs, which are moving transient structures. We report observations from the FAST satellite of a localized large-amplitude parallel electric field (∼ 300 mV m−1 recorded at the edges of the auroral density cavity. In agreement with laboratory experiments, on the high-potential side of the DL, elementary radiation events are detected. They occur substantially above the local electron gyrofrequency and are associated with the presence of electron holes. The velocity of these nonlinear structures can be derived from the measurement of the Doppler-shifted AKR frequency spectrum above the electron gyrofrequency. The generated electron holes appear as the nonlinear evolution of electrostatic waves generated by the electron–electron two-stream instability because they propagate at about half the beam velocity. It is pointed out that, in the vicinity of a DL, the shape of the electron distribution gives rise to a significant power recorded in the left-hand polarized ordinary (LO mode.

  8. ActivitySim: large-scale agent based activity generation for infrastructure simulation

    Energy Technology Data Exchange (ETDEWEB)

    Gali, Emmanuel [Los Alamos National Laboratory; Eidenbenz, Stephan [Los Alamos National Laboratory; Mniszewski, Sue [Los Alamos National Laboratory; Cuellar, Leticia [Los Alamos National Laboratory; Teuscher, Christof [PORTLAND STATE UNIV

    2008-01-01

    The United States' Department of Homeland Security aims to model, simulate, and analyze critical infrastructure and their interdependencies across multiple sectors such as electric power, telecommunications, water distribution, transportation, etc. We introduce ActivitySim, an activity simulator for a population of millions of individual agents each characterized by a set of demographic attributes that is based on US census data. ActivitySim generates daily schedules for each agent that consists of a sequence of activities, such as sleeping, shopping, working etc., each being scheduled at a geographic location, such as businesses or private residences that is appropriate for the activity type and for the personal situation of the agent. ActivitySim has been developed as part of a larger effort to understand the interdependencies among national infrastructure networks and their demand profiles that emerge from the different activities of individuals in baseline scenarios as well as emergency scenarios, such as hurricane evacuations. We present the scalable software engineering principles underlying ActivitySim, the socia-technical modeling paradigms that drive the activity generation, and proof-of-principle results for a scenario in the Twin Cities, MN area of 2.6 M agents.

  9. Understanding Flash Flood Generation in the Arid Region of the Dead Sea

    Science.gov (United States)

    Merz, R.; Hennig, H.; Rödiger, T.; Laronne, J. B.

    2017-12-01

    The arid region of the Dead Sea is prone by flash floods. Such flash floods in (semi-) arid regions are impressive. Generated within minutes, the peak unit discharge can be as high as 25 m³/s km². Floods are the main mechanism supplying water to alluvial aquifers, forming fluvial landscapes including canyons and often causing damage to humans, infrastructure, industry and tourism. Existing hydrological models in this region focus on peak discharges. However, these models are often based on simplified concepts and/or on concepts which were developed for humid regions. To more closely relate such models to local conditions, processes within catchments where floods occur require consideration. Therefore, a measurement network of rain gauges and level loggers to monitor runoff was installed in the beginning of the 2015/16 hydrological season in the tributaries of Wadi Arugot. The Arugot catchment is one of the largest ephemeral Wadis draining to the western shoreline of the Dead Sea at 450 m bsl. Due to the high gradient in elevation, the climate within the basin ranges from semiarid in the Judean Mountains, to hyper-arid near the Dead Sea with respective mean annual rainfall of 650 and 50 mm. The installed rain gauge network in the mountains is more dense compared to the Dead Sea area. Arid to semiarid catchments have different runoff generation processes compared to humid regions due local storm rainfall, low density of vegetation cover as well as patchy and shallow soil. These characteristics limit the contribution of groundwater flow, saturated overland flow and shallow subsurface flow, and therefore Hortonian overland flow is the most important contributor to overland flow. First analyses of the runoff data have shown that the storage capacity in the mountain area is lower compared to the more arid region. This is an evidence of high transmission losses in the coarse gravel wadi bed, therefore having a high permeability. The rain event duration and the amount of

  10. Exome sequencing generates high quality data in non-target regions

    Directory of Open Access Journals (Sweden)

    Guo Yan

    2012-05-01

    Full Text Available Abstract Background Exome sequencing using next-generation sequencing technologies is a cost efficient approach to selectively sequencing coding regions of human genome for detection of disease variants. A significant amount of DNA fragments from the capture process fall outside target regions, and sequence data for positions outside target regions have been mostly ignored after alignment. Result We performed whole exome sequencing on 22 subjects using Agilent SureSelect capture reagent and 6 subjects using Illumina TrueSeq capture reagent. We also downloaded sequencing data for 6 subjects from the 1000 Genomes Project Pilot 3 study. Using these data, we examined the quality of SNPs detected outside target regions by computing consistency rate with genotypes obtained from SNP chips or the Hapmap database, transition-transversion (Ti/Tv ratio, and percentage of SNPs inside dbSNP. For all three platforms, we obtained high-quality SNPs outside target regions, and some far from target regions. In our Agilent SureSelect data, we obtained 84,049 high-quality SNPs outside target regions compared to 65,231 SNPs inside target regions (a 129% increase. For our Illumina TrueSeq data, we obtained 222,171 high-quality SNPs outside target regions compared to 95,818 SNPs inside target regions (a 232% increase. For the data from the 1000 Genomes Project, we obtained 7,139 high-quality SNPs outside target regions compared to 1,548 SNPs inside target regions (a 461% increase. Conclusions These results demonstrate that a significant amount of high quality genotypes outside target regions can be obtained from exome sequencing data. These data should not be ignored in genetic epidemiology studies.

  11. The Magnetic Free Energy in Active Regions

    Science.gov (United States)

    Metcalf, Thomas R.; Mickey, Donald L.; LaBonte, Barry J.

    2001-01-01

    The magnetic field permeating the solar atmosphere governs much of the structure, morphology, brightness, and dynamics observed on the Sun. The magnetic field, especially in active regions, is thought to provide the power for energetic events in the solar corona, such as solar flares and Coronal Mass Ejections (CME) and is believed to energize the hot coronal plasma seen in extreme ultraviolet or X-rays. The question remains what specific aspect of the magnetic flux governs the observed variability. To directly understand the role of the magnetic field in energizing the solar corona, it is necessary to measure the free magnetic energy available in active regions. The grant now expiring has demonstrated a new and valuable technique for observing the magnetic free energy in active regions as a function of time.

  12. On the evaluation of lifetime of evaporative tubes of once-through steam generators at steam-generating surface temperature oscillations in the burnout region

    International Nuclear Information System (INIS)

    Vorob'ev, V.A.; Loshchinin, V.M.; Remizov, O.V.

    1978-01-01

    Suggested is a method for evaluation of a stressed state of evaporation tubes of once-through steam generators at temperature oscillations in the burnout region. Calculated is the amplitude of steam-generating surface temperature oscillations in the burnout region depending on the frequency of a liquid-steam boundary transfer and on this basis determined are thermal stresses in a tube wall. Knowing a fatigue curve gives the possibility to evaluate a heat transfer tube lifetime

  13. IAEA activities on steam generator life management

    International Nuclear Information System (INIS)

    Gueorguiev, B.; Lyssakov, V.; Trampus, P.

    2002-01-01

    The International Atomic Energy Agency (IAEA) carries out a set of activities in the field of Nuclear Power Plant (NPP) life management. Main activities within this area are implemented through the Technical Working Group on Life Management of NPPs, and mostly concentrated on studies of understanding mechanisms of degradation and their monitoring, optimisation of maintenance management, economic aspects, proven practices of and approaches to plant life management including decommissioning. The paper covers two ongoing activities related to steam generator life management: the International Database on NPP Steam Generators and the Co-ordinated Research Project on Verification of WWER Steam Generator Tube Integrity (WWER is the Russian designed PWR). The lifetime assessment of main components relies on an ability to assess their condition and predict future degradation trends, which to a large extent is dependent on the availability of relevant data. Effective management of ageing and degradation processes requires a large amount of data. Several years ago the IAEA started to work on the International Database on NPP Life Management. This is a multi-module database consisting of modules such as reactor pressure vessels materials, piping, steam generators, and concrete structures. At present the work on pressure vessel materials, on piping as well as on steam generator is completed. The paper will present the concept and structure of the steam generator module of the database. In countries operating WWER NPPs, there are big differences in the eddy current inspection strategy and practice as well as in the approach to steam generator heat exchanger tube structural integrity assessment. Responding to the need for a co-ordinated research to compare eddy current testing results with destructive testing using pulled out tubes from WWER steam generators, the IAEA launched this project. The main objectives of the project are to summarise the operating experiences of WWER

  14. A Study on Grid-Square Statistics Based Estimation of Regional Electricity Demand and Regional Potential Capacity of Distributed Generators

    Science.gov (United States)

    Kato, Takeyoshi; Sugimoto, Hiroyuki; Suzuoki, Yasuo

    We established a procedure for estimating regional electricity demand and regional potential capacity of distributed generators (DGs) by using a grid square statistics data set. A photovoltaic power system (PV system) for residential use and a co-generation system (CGS) for both residential and commercial use were taken into account. As an example, the result regarding Aichi prefecture was presented in this paper. The statistical data of the number of households by family-type and the number of employees by business category for about 4000 grid-square with 1km × 1km area was used to estimate the floor space or the electricity demand distribution. The rooftop area available for installing PV systems was also estimated with the grid-square statistics data set. Considering the relation between a capacity of existing CGS and a scale-index of building where CGS is installed, the potential capacity of CGS was estimated for three business categories, i.e. hotel, hospital, store. In some regions, the potential capacity of PV systems was estimated to be about 10,000kW/km2, which corresponds to the density of the existing area with intensive installation of PV systems. Finally, we discussed the ratio of regional potential capacity of DGs to regional maximum electricity demand for deducing the appropriate capacity of DGs in the model of future electricity distribution system.

  15. Local Helioseismology of Emerging Active Regions: A Case Study

    Science.gov (United States)

    Kosovichev, Alexander G.; Zhao, Junwei; Ilonidis, Stathis

    2018-04-01

    Local helioseismology provides a unique opportunity to investigate the subsurface structure and dynamics of active regions and their effect on the large-scale flows and global circulation of the Sun. We use measurements of plasma flows in the upper convection zone, provided by the Time-Distance Helioseismology Pipeline developed for analysis of solar oscillation data obtained by Helioseismic and Magnetic Imager (HMI) on Solar Dynamics Observatory (SDO), to investigate the subsurface dynamics of emerging active region NOAA 11726. The active region emergence was detected in deep layers of the convection zone about 12 hours before the first bipolar magnetic structure appeared on the surface, and 2 days before the emergence of most of the magnetic flux. The speed of emergence determined by tracking the flow divergence with depth is about 1.4 km/s, very close to the emergence speed in the deep layers. As the emerging magnetic flux becomes concentrated in sunspots local converging flows are observed beneath the forming sunspots. These flows are most prominent in the depth range 1-3 Mm, and remain converging after the formation process is completed. On the larger scale converging flows around active region appear as a diversion of the zonal shearing flows towards the active region, accompanied by formation of a large-scale vortex structure. This process occurs when a substantial amount of the magnetic flux emerged on the surface, and the converging flow pattern remains stable during the following evolution of the active region. The Carrington synoptic flow maps show that the large-scale subsurface inflows are typical for active regions. In the deeper layers (10-13 Mm) the flows become diverging, and surprisingly strong beneath some active regions. In addition, the synoptic maps reveal a complex evolving pattern of large-scale flows on the scale much larger than supergranulation

  16. Evaluation of computer-based NDE techniques and regional support of inspection activities

    International Nuclear Information System (INIS)

    Taylor, T.T.; Kurtz, R.J.; Heasler, P.G.; Doctor, S.R.

    1991-01-01

    This paper describes the technical progress during fiscal year 1990 for the program entitled 'Evaluation of Computer-Based nondestructive evaluation (NDE) Techniques and Regional Support of Inspection Activities.' Highlights of the technical progress include: development of a seminar to provide basic knowledge required to review and evaluate computer-based systems; review of a typical computer-based field procedure to determine compliance with applicable codes, ambiguities in procedure guidance, and overall effectiveness and utility; design and fabrication of a series of three test blocks for NRC staff use for training or audit of UT systems; technical assistance in reviewing (1) San Onofre ten year reactor pressure vessel inservice inspection activities and (2) the capability of a proposed phased array inspection of the feedwater nozzle at Oyster Creek; completion of design calculations to determine the feasibility and significance of various sizes of mockup assemblies that could be used to evaluate the effectiveness of eddy current examinations performed on steam generators; and discussion of initial mockup design features and methods for fabricating flaws in steam generator tubes

  17. The Maximum Free Magnetic Energy Allowed in a Solar Active Region

    Science.gov (United States)

    Moore, Ronald L.; Falconer, David A.

    2009-01-01

    Two whole-active-region magnetic quantities that can be measured from a line-of-sight magnetogram are (sup L) WL(sub SG), a gauge of the total free energy in an active region's magnetic field, and sup L(sub theta), a measure of the active region's total magnetic flux. From these two quantities measured from 1865 SOHO/MDI magnetograms that tracked 44 sunspot active regions across the 0.5 R(sub Sun) central disk, together with each active region's observed production of CMEs, X flares, and M flares, Falconer et al (2009, ApJ, submitted) found that (1) active regions have a maximum attainable free magnetic energy that increases with the magnetic size (sup L) (sub theta) of the active region, (2) in (Log (sup L)WL(sub SG), Log(sup L) theta) space, CME/flare-productive active regions are concentrated in a straight-line main sequence along which the free magnetic energy is near its upper limit, and (3) X and M flares are restricted to large active regions. Here, from (a) these results, (b) the observation that even the greatest X flares produce at most only subtle changes in active region magnetograms, and (c) measurements from MSFC vector magnetograms and from MDI line-of-sight magnetograms showing that practically all sunspot active regions have nearly the same area-averaged magnetic field strength: =- theta/A approximately equal to 300 G, where theta is the active region's total photospheric flux of field stronger than 100 G and A is the area of that flux, we infer that (1) the maximum allowed ratio of an active region's free magnetic energy to its potential-field energy is 1, and (2) any one CME/flare eruption releases no more than a small fraction (less than 10%) of the active region's free magnetic energy. This work was funded by NASA's Heliophysics Division and NSF's Division of Atmospheric Sciences.

  18. ASSESSMENT OF HUMAN RESOURCES FOR REGIONAL INNOVATION ACTIVITY

    Directory of Open Access Journals (Sweden)

    R. R. Lukyanova

    2010-03-01

    Full Text Available The paper deals with the issues of human resource development regarding an innovation activity. Concepts of labor and human resources have been surveyed. An integral index for assessment of human resources for regional innovation activity has been developed and assessment of the Russian regions has been made on the basis of it. Development tendencies of modern human resources for innovation activity in Russia have been revealed.

  19. Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

    Science.gov (United States)

    1998-05-29

    AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

  20. Solar active region display system

    Science.gov (United States)

    Golightly, M.; Raben, V.; Weyland, M.

    2003-04-01

    The Solar Active Region Display System (SARDS) is a client-server application that automatically collects a wide range of solar data and displays it in a format easy for users to assimilate and interpret. Users can rapidly identify active regions of interest or concern from color-coded indicators that visually summarize each region's size, magnetic configuration, recent growth history, and recent flare and CME production. The active region information can be overlaid onto solar maps, multiple solar images, and solar difference images in orthographic, Mercator or cylindrical equidistant projections. Near real-time graphs display the GOES soft and hard x-ray flux, flare events, and daily F10.7 value as a function of time; color-coded indicators show current trends in soft x-ray flux, flare temperature, daily F10.7 flux, and x-ray flare occurrence. Through a separate window up to 4 real-time or static graphs can simultaneously display values of KP, AP, daily F10.7 flux, GOES soft and hard x-ray flux, GOES >10 and >100 MeV proton flux, and Thule neutron monitor count rate. Climatologic displays use color-valued cells to show F10.7 and AP values as a function of Carrington/Bartel's rotation sequences - this format allows users to detect recurrent patterns in solar and geomagnetic activity as well as variations in activity levels over multiple solar cycles. Users can customize many of the display and graph features; all displays can be printed or copied to the system's clipboard for "pasting" into other applications. The system obtains and stores space weather data and images from sources such as the NOAA Space Environment Center, NOAA National Geophysical Data Center, the joint ESA/NASA SOHO spacecraft, and the Kitt Peak National Solar Observatory, and can be extended to include other data series and image sources. Data and images retrieved from the system's database are converted to XML and transported from a central server using HTTP and SOAP protocols, allowing

  1. Estimating evaporative vapor generation from automobiles based on parking activities

    International Nuclear Information System (INIS)

    Dong, Xinyi; Tschantz, Michael; Fu, Joshua S.

    2015-01-01

    A new approach is proposed to quantify the evaporative vapor generation based on real parking activity data. As compared to the existing methods, two improvements are applied in this new approach to reduce the uncertainties: First, evaporative vapor generation from diurnal parking events is usually calculated based on estimated average parking duration for the whole fleet, while in this study, vapor generation rate is calculated based on parking activities distribution. Second, rather than using the daily temperature gradient, this study uses hourly temperature observations to derive the hourly incremental vapor generation rates. The parking distribution and hourly incremental vapor generation rates are then adopted with Wade–Reddy's equation to estimate the weighted average evaporative generation. We find that hourly incremental rates can better describe the temporal variations of vapor generation, and the weighted vapor generation rate is 5–8% less than calculation without considering parking activity. - Highlights: • We applied real parking distribution data to estimate evaporative vapor generation. • We applied real hourly temperature data to estimate hourly incremental vapor generation rate. • Evaporative emission for Florence is estimated based on parking distribution and hourly rate. - A new approach is proposed to quantify the weighted evaporative vapor generation based on parking distribution with an hourly incremental vapor generation rate

  2. NMDA receptor antagonist-enhanced high frequency oscillations: are they generated broadly or regionally specific?

    Science.gov (United States)

    Olszewski, Maciej; Dolowa, Wioleta; Matulewicz, Pawel; Kasicki, Stefan; Hunt, Mark J

    2013-12-01

    Systemic administration of NMDA receptor antagonists, used to model schizophrenia, increase the power of high-frequency oscillations (130-180Hz, HFO) in a variety of neuroanatomical and functionally distinct brain regions. However, it is unclear whether HFO are independently and locally generated or instead spread from a distant source. To address this issue, we used local infusion of tetrodotoxin (TTX) to distinct brain areas to determine how accurately HFO recorded after injection of NMDAR antagonists reflect the activity actually generated at the electrode tip. Changes in power were evaluated in local field potentials (LFPs) recorded from the nucleus accumbens (NAc), prefrontal cortex and caudate and in electrocorticograms (ECoGs) from visual and frontal areas. HFO recorded in frontal and visual cortices (ECoGs) or in the prefrontal cortex, caudate (LFPs) co-varied in power and frequency with observed changes in the NAc. TTX infusion to the NAc immediately and profoundly reduced the power of accumbal HFO which correlated with changes in HFO recorded in distant cortical sites. In contrast, TTX infusion to the prefrontal cortex did not change HFO power recorded locally, although gamma power was reduced. A very similar result was found after TTX infusion to the caudate. These findings raise the possibility that the NAc is an important neural generator. Our data also support existing studies challenging the idea that high frequencies recorded in LFPs are necessarily generated at the recording site. Copyright © 2013 Elsevier B.V. and ECNP. All rights reserved.

  3. Twist of Magnetic Fields in Solar Active Regions Hongqi Zhang ...

    Indian Academy of Sciences (India)

    tribpo

    in active regions also shows the butterfly pattern through the solar cycle. And, less than 30% of the active regions do not follow the general trend (Zhang & Bao 1998). The longitudinal distribution of current helicity parameter h|| of active regions in both the hemispheres in the last decade was presented by Zhang & Bao ...

  4. REGIONALIZATION OF MANAGEMENT PROCESS BY INNOVATIVE ACTIVITY

    Directory of Open Access Journals (Sweden)

    E. V. Sibirskaia

    2014-01-01

    Full Text Available Summary. In current market conditions, the economy and Russia's accession to international trade scholars and experts from various fields of knowledge paying special attention to a huge set of regional problems. The growing role of regional research determines the level of establishing effective mechanisms for the implementation of the economic interests of actors as well as economic development and improving the quality of human life is the priority objectives of federal, regional and local authorities. Today, the Russian economic science faces a global goal - to develop ways and means of transformation of the Russian economy and bring it to a path of sustainable, innovative development, providing new quality of life. Achieving this goal must surely be a central task of the Russian economics and politics, as in the near future and the long term In article authors opened the maintenance of determinants of innovative development of the territory, mediated by strengthening of regionalization of management by innovative activity: condition of resource and innovative potential; the developed forms and nature of interaction between public authorities of regional level, local community and business; applied forms of integration of subjects of managing for realization of their innovative potential due to expansion of opportunities of participation in the perspective directions of scientific and technical, economic and social development; system of the incentives developing favorable conditions for introduction and development of innovative technologies, and also increases in the enterprise activity, formed by the external institutional environment; regional economic policy as instrument of increase of efficiency of innovative activity.

  5. On the Reconstruction of the Convection Pattern Below an Active Region of Solar Corona

    International Nuclear Information System (INIS)

    Pirot, Dorian; Gaudet, Jonathan; Vincent, Alain

    2012-01-01

    In order to better understand magneto-convective patterns and flux emergence, we use the Nudging Back and Forth, a data assimilation method with an anelastic convection model to reconstruct the convection zone below a solar active region from observed solar surface magnetograms. To mimic photosphere, vector magnetograms are computed using force free hypothesis. We find that the observed arcade system of AR9077-20000714 ( t he slinky ) of magnetic lines is actually formed by Ω and U loops generated in the convection zone. We generate temperature maps at top of the convective zone and find that high magnetic fields on either sides of the neutral line produce a local cooling by impeding the overturning motions.

  6. Stochastic modeling of the hypothalamic pulse generator activity.

    Science.gov (United States)

    Camproux, A C; Thalabard, J C; Thomas, G

    1994-11-01

    Luteinizing hormone (LH) is released by the pituitary in discrete pulses. In the monkey, the appearance of LH pulses in the plasma is invariably associated with sharp increases (i.e, volleys) in the frequency of the hypothalamic pulse generator electrical activity, so that continuous monitoring of this activity by telemetry provides a unique means to study the temporal structure of the mechanism generating the pulses. To assess whether the times of occurrence and durations of previous volleys exert significant influence on the timing of the next volley, we used a class of periodic counting process models that specify the stochastic intensity of the process as the product of two factors: 1) a periodic baseline intensity and 2) a stochastic regression function with covariates representing the influence of the past. This approach allows the characterization of circadian modulation and memory range of the process underlying hypothalamic pulse generator activity, as illustrated by fitting the model to experimental data from two ovariectomized rhesus monkeys.

  7. THE 'MAIN SEQUENCE' OF EXPLOSIVE SOLAR ACTIVE REGIONS: DISCOVERY AND INTERPRETATION

    Energy Technology Data Exchange (ETDEWEB)

    Falconer, David A; Moore, Ronald L; Adams, Mitzi [Space Science Office, VP62, Marshall Space Flight Center, Huntsville, AL 35812 (United States); Gary, G. Allen [Center for Space Plasma and Aeronomic Research, University of Alabama in Huntsville, Huntsville, AL 35899 (United States)], E-mail: David.falconer@msfc.nasa.gov

    2009-08-01

    We examine the location and distribution of the production of coronal mass ejections (CMEs) and major flares by sunspot active regions in the phase space of two whole-active-region magnetic quantities measured from 1897 SOHO/MDI magnetograms. These magnetograms track the evolution of 44 active regions across the central disk of radius 0.5 R {sub Sun}. The two quantities are {sup L}WL{sub SG}, a gauge of the total free energy in an active region's magnetic field, and {sup L}{phi}, a measure of the active region's total magnetic flux. From these data and each active region's history of production of CMEs, X flares, and M flares, we find (1) that CME/flare-productive active regions are concentrated in a straight-line 'main sequence' in (log {sup L}WL{sub SG}, log {sup L}{phi}) space, (2) that main-sequence active regions have nearly their maximum attainable free magnetic energy, and (3) evidence that this arrangement plausibly results from equilibrium between input of free energy to an explosive active region's magnetic field in the chromosphere and corona by contortion of the field via convection in and below the photosphere and loss of free energy via CMEs, flares, and coronal heating, an equilibrium between energy gain and loss that is analogous to that of the main sequence of hydrogen-burning stars in (mass, luminosity) space.

  8. THE 'MAIN SEQUENCE' OF EXPLOSIVE SOLAR ACTIVE REGIONS: DISCOVERY AND INTERPRETATION

    International Nuclear Information System (INIS)

    Falconer, David A.; Moore, Ronald L.; Adams, Mitzi; Gary, G. Allen

    2009-01-01

    We examine the location and distribution of the production of coronal mass ejections (CMEs) and major flares by sunspot active regions in the phase space of two whole-active-region magnetic quantities measured from 1897 SOHO/MDI magnetograms. These magnetograms track the evolution of 44 active regions across the central disk of radius 0.5 R Sun . The two quantities are L WL SG , a gauge of the total free energy in an active region's magnetic field, and L Φ, a measure of the active region's total magnetic flux. From these data and each active region's history of production of CMEs, X flares, and M flares, we find (1) that CME/flare-productive active regions are concentrated in a straight-line 'main sequence' in (log L WL SG , log L Φ) space, (2) that main-sequence active regions have nearly their maximum attainable free magnetic energy, and (3) evidence that this arrangement plausibly results from equilibrium between input of free energy to an explosive active region's magnetic field in the chromosphere and corona by contortion of the field via convection in and below the photosphere and loss of free energy via CMEs, flares, and coronal heating, an equilibrium between energy gain and loss that is analogous to that of the main sequence of hydrogen-burning stars in (mass, luminosity) space.

  9. Generation adequacy and transmission interconnection in regional electricity markets

    International Nuclear Information System (INIS)

    Cepeda, Mauricio; Saguan, Marcelo; Finon, Dominique; Pignon, Virginie

    2009-01-01

    The power system capacity adequacy has public good features that cannot be entirely solved by electricity markets. Regulatory intervention is then necessary and established methods have been used to assess adequacy and help regulators to fix this market failure. In regional electricity markets, transmission interconnections play an important role in contributing to adequacy. However, the adequacy problem and related policy are typically considered at a national level. This paper presents a simple model to study how the interconnection capacity interacts with generation adequacy. First results indicate that increasing interconnection capacity between systems improves adequacy up to a certain level; further increases do not procure additional adequacy improvements. Furthermore, besides adequacy improvement, increasing transmission capacity under asymmetric adequacy criteria or national system characteristics could create several concerns about externalities. These results imply that regional coordination of national adequacy policies is essential to internalise adequacy of cross-border effects.

  10. CALCULATING ENERGY STORAGE DUE TO TOPOLOGICAL CHANGES IN EMERGING ACTIVE REGION NOAA AR 11112

    International Nuclear Information System (INIS)

    Tarr, Lucas; Longcope, Dana

    2012-01-01

    The minimum current corona model provides a way to estimate stored coronal energy using the number of field lines connecting regions of positive and negative photospheric flux. This information is quantified by the net flux connecting pairs of opposing regions in a connectivity matrix. Changes in the coronal magnetic field, due to processes such as magnetic reconnection, manifest themselves as changes in the connectivity matrix. However, the connectivity matrix will also change when flux sources emerge or submerge through the photosphere, as often happens in active regions. We have developed an algorithm to estimate the changes in flux due to emergence and submergence of magnetic flux sources. These estimated changes must be accounted for in order to quantify storage and release of magnetic energy in the corona. To perform this calculation over extended periods of time, we must additionally have a consistently labeled connectivity matrix over the entire observational time span. We have therefore developed an automated tracking algorithm to generate a consistent connectivity matrix as the photospheric source regions evolve over time. We have applied this method to NOAA Active Region 11112, which underwent a GOES M2.9 class flare around 19:00 on 2010 October 16th, and calculated a lower bound on the free magnetic energy buildup of ∼8.25 × 10 30 erg over 3 days.

  11. Autonomous Voltage Security Regions to Prevent Cascading Trip Faults in Wind Turbine Generators

    DEFF Research Database (Denmark)

    Niu, Tao; Guo, Qinglai; Sun, Hongbin

    2016-01-01

    Cascading trip faults in large-scale wind power centralized integration areas bring new challenges to the secure operation of power systems. In order to deal with the complexity of voltage security regions and the computation difficulty, this paper proposes an autonomous voltage security region...... wind farm, an AVSR is determined to guarantee the normal operation of each wind turbine generator (WTG), while in the control center, each region is designed in order to guarantee secure operation both under normal conditions and after an N-1 contingency. A real system in Northern China was used...

  12. ON THE NON-KOLMOGOROV NATURE OF FLARE-PRODUCTIVE SOLAR ACTIVE REGIONS

    Energy Technology Data Exchange (ETDEWEB)

    Mandage, Revati S. [Physics and Astronomy Department, Rice University, 6100 Main MS-61, Houston, TX 77005-1827 (United States); McAteer, R. T. James, E-mail: mcateer@nmsu.edu [Department of Astronomy, New Mexico State University, MSC 4500, Las Cruces, NM 88001 (United States)

    2016-12-20

    A magnetic power spectral analysis is performed on 53 solar active regions, observed from 2011 August to 2012 July. Magnetic field data obtained from the Helioseismic and Magnetic Imager, inverted as Active Region Patches, are used to study the evolution of the magnetic power index as each region rotates across the solar disk. Active regions are classified based on the numbers and sizes of solar flares they produce in order to study the relationship between flare productivity and the magnetic power index. The choice of window size and inertial range plays a key role in determining the correct magnetic power index. The overall distribution of magnetic power indices has a range of 1.0–2.5. Flare-quiet regions peak at a value of 1.6. However, flare-productive regions peak at a value of 2.2. Overall, the histogram of the distribution of power indices of flare-productive active regions is well separated from flare-quiet active regions. Only 12% of flare-quiet regions exhibit an index greater than 2, whereas 90% of flare-productive regions exhibit an index greater than 2. Flare-quiet regions exhibit a high temporal variance (i.e., the index fluctuates between high and low values), whereas flare-productive regions maintain an index greater than 2 for several days. This shows the importance of including the temporal evolution of active regions in flare prediction studies, and highlights the potential of a 2–3 day prediction window for space weather applications.

  13. Active Pesticide Production Points, Region 9, 2013, US EPA Region 9

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer represents Active Pesticide Producing Establishments in USEPA Region 9 (AZ, CA, HI and NV) that reported production for the year 2013. Pesticide...

  14. Energy Harvesting Cycles of Dielectric ElectroActive Polymer Generators

    DEFF Research Database (Denmark)

    Dimopoulos, Emmanouil; Trintis, Ionut; Munk-Nielsen, Stig

    2012-01-01

    Energy harvesting via Dielectric ElectroActive Polymer (DEAP) generators has attracted much of the scientific interest over the past few years, mainly due to the advantages that these smart materials offer against competing technologies, as electromagnetic generators and piezoelectrics. Their hig......Energy harvesting via Dielectric ElectroActive Polymer (DEAP) generators has attracted much of the scientific interest over the past few years, mainly due to the advantages that these smart materials offer against competing technologies, as electromagnetic generators and piezoelectrics....... Their higher energy density, superior low-speed performance, light-weighted nature as well as their shapely structure have rendered DEAPs candidate solutions for various actuation and energy harvesting applications. In this paper, a thoroughly analysis of all energy harvesting operational cycles of a DEAP...

  15. RCA activities in the Asian and Pacific Region

    International Nuclear Information System (INIS)

    Kobayashi, M.

    1984-01-01

    So-called ''RCA'' activities - practical work undertaken within the framework of a Regional Co-operative Agreement for Research, Development and Training related to Nuclear Science and Technology for the Asian and Pacific region - are widely regarded as an example of successful co-operative effort in the application of nuclear techniques at a regional level. Activities undertaken to promote the transfer of nuclear technology within the framework of the RCA cover a large spectrum of nuclear applications in agriculture and food production, medicine, study of the environment, industry, and physics. Fourteen projects are operational this year (1984)

  16. Generating regionalized neuronal cells from pluripotency, a step-by-step protocol

    Directory of Open Access Journals (Sweden)

    Agnete eKirkeby

    2013-01-01

    Full Text Available Human pluripotent stem cells possess the potential to generate cells for regenerative therapies in patients with neurodegenerative diseases, and constitute an excellent cell source for studying human neural development and disease modeling. Protocols for neural differentiation of human pluripotent stem cells have undergone significant progress during recent years, allowing for rapid and synchronized neural conversion. Differentiation procedures can further be combined with accurate and efficient positional patterning to yield regionalized neural progenitors and subtype-specific neurons corresponding to different parts of the developing human brain. Here, we present a step-by-step protocol for neuralization and regionalization of human pluripotent cells for transplantation studies or in vitro analysis.

  17. GaN-based vertical-cavity laser performance improvements using tunnel-junction-cascaded active regions

    International Nuclear Information System (INIS)

    Piprek, Joachim

    2014-01-01

    This Letter investigates the output power enhancement achieved by tunnel junction insertion into the InGaN multi-quantum well (MQW) active region of a 410 nm vertical-cavity surface-emitting laser which enables the repeated use of carriers for light generation (carrier recycling). While the number of quantum wells remains unchanged, the tunnel junction eliminates absorption caused by the non-uniform MQW carrier distribution. The thermal resistance drops and the excess bias lead to a surprisingly small rise in self-heating.

  18. Activation of different cerebral functional regions following ...

    African Journals Online (AJOL)

    Background: To explore the brain function regions characteristics of the acupoint combination, this study observed activity changes in the brain regions of healthy volunteers after acupuncture at both Taixi (KI3) and Taichong (LR3) (KI3 + LR3) and KI3 alone using resting-state functional magnetic resonance imaging(fMRI).

  19. Active Ageing Level of Older Persons: Regional Comparison in Thailand

    Directory of Open Access Journals (Sweden)

    Md. Nuruzzaman Haque

    2016-01-01

    Full Text Available Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1 has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p<0.001. Mean AAI in Central region is lower than North, Northeast, and South regions but there is no significant difference in the latter three regions of Thailand. Special emphasis should be given to Central region and policy should be undertaken for increasing active ageing level. Implementation of an Integrated Active Ageing Package (IAAP, containing policies for older persons to improve their health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons’ active ageing level in Thailand.

  20. Emergent Public Spaces: Generative Activities on Function Interpolation

    Science.gov (United States)

    Carmona, Guadalupe; Dominguez, Angeles; Krause, Gladys; Duran, Pablo

    2011-01-01

    This study highlights ways in which generative activities may be coupled with network-based technologies in the context of teacher preparation to enhance preservice teachers' cognizance of how their own experience as students provides a blueprint for the learning environments they may need to generate in their future classrooms. In this study, the…

  1. The Photospheric Flow near the Flare Locations of Active Regions

    Indian Academy of Sciences (India)

    tribpo

    in the active regions along with few locations of upflows. The localised upflows are observed in the light bridges and emerging flux regions with different speeds (Beckers & Schroter 1969). The flow patterns of flare locations in the active regions are observed by using the tower vector magnetograph (TVM) of Marshall.

  2. Region-selective electroless gold plating on polycarbonate sheets by UV-patterning in combination with silver activating

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Qinghua [Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University, Zijin' gang Campus, Hangzhou 310058 (China); Chen Hengwu, E-mail: hwchen@zju.edu.c [Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University, Zijin' gang Campus, Hangzhou 310058 (China); Wang Yi [Institute of Microanalytical Systems, Department of Chemistry, Zhejiang University, Zijin' gang Campus, Hangzhou 310058 (China)

    2010-02-28

    A simple, time- and cost-effective approach for region-selective metalization of polycarbonate (PC) surface has been established by combining photoresist-free UV-patterning with tin- and amine-free silver activating and electroless gold plating. The surface of PC sheets was exposed to the UV lights emitted from a low-pressure mercury lamp through a photomask, the micro pattern on the mask being transferred to the PC surface due to the photochemical generation of carboxyl groups on the UV-exposed region. The UV-exposed PC sheets were then treated with an ammoniacal AgNO{sub 3} solution, so that the silver ions were chemisorbed by the photochemically generated carboxyl groups. When the Ag{sup +}-adsorbed PC sheet was immersed into an electroless gold plating bath, shiny gold film quickly deposited on the UV-exposed region, resulting in the formation of a micro gold devices on the PC surface. The whole plating process including UV-exposure, surface activating and gold plating can be completed in about 3-4 h. Attenuated total reflection Fourier transformation infrared spectrometer (ATR-FT-IR), X-ray photoelectron spectroscopy (XPS), atomic force microscope (AFM) and scanning electron microscope (SEM) were employed to trace the surface change during the plating process. Cyclic voltammetry (CV) and Scotch-tape test were employed to characterize the electrochemical properties and adhesion strength of the prepared micro gold devices, respectively. The prepared micro gold electrodes were demonstrated for amperometric detection of hydrogen peroxide.

  3. MAG4 versus alternative techniques for forecasting active region flare productivity

    Science.gov (United States)

    Falconer, David A; Moore, Ronald L; Barghouty, Abdulnasser F; Khazanov, Igor

    2014-01-01

    MAG4 is a technique of forecasting an active region's rate of production of major flares in the coming few days from a free magnetic energy proxy. We present a statistical method of measuring the difference in performance between MAG4 and comparable alternative techniques that forecast an active region's major-flare productivity from alternative observed aspects of the active region. We demonstrate the method by measuring the difference in performance between the “Present MAG4” technique and each of three alternative techniques, called “McIntosh Active-Region Class,” “Total Magnetic Flux,” and “Next MAG4.” We do this by using (1) the MAG4 database of magnetograms and major flare histories of sunspot active regions, (2) the NOAA table of the major-flare productivity of each of 60 McIntosh active-region classes of sunspot active regions, and (3) five technique performance metrics (Heidke Skill Score, True Skill Score, Percent Correct, Probability of Detection, and False Alarm Rate) evaluated from 2000 random two-by-two contingency tables obtained from the databases. We find that (1) Present MAG4 far outperforms both McIntosh Active-Region Class and Total Magnetic Flux, (2) Next MAG4 significantly outperforms Present MAG4, (3) the performance of Next MAG4 is insensitive to the forward and backward temporal windows used, in the range of one to a few days, and (4) forecasting from the free-energy proxy in combination with either any broad category of McIntosh active-region classes or any Mount Wilson active-region class gives no significant performance improvement over forecasting from the free-energy proxy alone (Present MAG4). Key Points Quantitative comparison of performance of pairs of forecasting techniques Next MAG4 forecasts major flares more accurately than Present MAG4 Present MAG4 forecast outperforms McIntosh AR Class and total magnetic flux PMID:26213517

  4. Diagnostics of Coronal Heating in Solar Active Regions

    Science.gov (United States)

    Fludra, Andrzej; Hornsey, Christopher; Nakariakov, Valery

    2015-04-01

    We aim to develop a diagnostic method for the coronal heating mechanism in active region loops. Observational constraints on coronal heating models have been sought using measurements in the X-ray and EUV wavelengths. Statistical analysis, using EUV emission from many active regions, was done by Fludra and Ireland (2008) who studied power-law relationships between active region integrated magnetic flux and emission line intensities. A subsequent study by Fludra and Warren (2010) for the first time compared fully resolved images in an EUV spectral line of OV 63.0 nm with the photospheric magnetic field, leading to the identification of a dominant, ubiquitous variable component of the transition region EUV emission and a discovery of a steady basal heating, and deriving the dependence of the basal heating rate on the photospheric magnetic flux density. In this study, we compare models of single coronal loops with EUV observations. We assess to what degree observations of individual coronal loops made in the EUV range are capable of providing constraints on the heating mechanism. We model the coronal magnetic field in an active region using an NLFF extrapolation code applied to a photospheric vector magnetogram from SDO/HMI and select several loops that match an SDO/AIA 171 image of the same active region. We then model the plasma in these loops using a 1D hydrostatic code capable of applying an arbitrary heating rate as a function of magnetic field strength along the loop. From the plasma parameters derived from this model, we calculate the EUV emission along the loop in AIA 171 and 335 bands, and in pure spectral lines of Fe IX 17.1 nm and Fe XVI 33.5 nm. We use different spatial distributions of the heating function: concentrated near the loop top, uniform and concentrated near the footpoints, and investigate their effect on the modelled EUV intensities. We find a diagnostics based on the dependence of the total loop intensity on the shape of the heating function

  5. Sports participation, physical activity, and health in the European regions.

    Science.gov (United States)

    Lera-López, Fernando; Marco, Rocio

    2018-08-01

    In a context of stagnation of the level of health-enhancing physical activity in Europe, this study examines the geographical stratification of sports participation and physical activity (PA) at the regional level in 28 European countries. While previous research has focused on the national approach, this study considers the regional level across 208 European regions. Individual survey data from the Eurobarometer 80.2 is combined with a regional-level approach to the 208 regions to quantify sports participation and PA at the regional level. The results show important differences and a geographical stratification of sports participation and PA among the European regions, albeit following different patterns. In particular, a north-south gap is identified in terms of PA rates and an east-west gap is detected in terms of sports participation levels. Applying the cluster technique, a taxonomy of four different European regions is developed considering both types of indicators. Finally, the existence of sports spatial spillovers among regions is verified, obtaining a positive autocorrelation among neighbouring regions for being involved in PA and sporting activities. The results may have significant implications in terms of policy measures to improve health through PA and sports participation at the regional level in Europe.

  6. N-terminal region of gelsolin induces apoptosis of activated hepatic stellate cells by a caspase-dependent mechanism.

    Directory of Open Access Journals (Sweden)

    Budhaditya Mazumdar

    Full Text Available Activated hepatic stellate cells (HSCs are the major source for alteration of extracellular matrix in fibrosis and cirrhosis. Conditioned medium (CM collected from immortalized human hepatocytes (IHH have earlier been shown to be responsible for apoptosis of HSCs. In this study, we have shown that antibodies raised against a peptide derived from a linear B-cell epitope in the N-terminal region of gelsolin identified a gelsolin fragment in IHH CM. Analysis of activated stellate cell death by CM collected from Huh7 cells transfected with plasmids encoding gelsolin deletion mutants suggested that the N-terminal half of gelsolin contained sequences which were responsible for stellate cell death. Further analysis determined that this activity was restricted to a region encompassing amino acids 1-70 in the gelsolin sequence; antibody directed to an epitope within this region was able to neutralize stellate cell death. Gelsolin modulation of cell death using this fragment involved upregulation of TRAIL-R1 and TRAIL-R2, and involved caspase 3 activation by extrinsic pathway. The apoptotic activity of N-terminal gelsolin fragments was restricted to activated but not quiescent stellate cells indicating its potential application in therapeutic use as an anti-fibrotic agent. Gelsolin fragments encompassing N-terminal regions in polypeptides of different molecular sizes were detected by N-terminal peptide specific antiserum in IHH CM immunoprecipitated with chronically HCV infected patient sera, suggesting the presence of autoantibodies generated against N-terminal gelsolin fragments in patients with chronic liver disease.

  7. Statistical downscaling and future scenario generation of temperatures for Pakistan Region

    Science.gov (United States)

    Kazmi, Dildar Hussain; Li, Jianping; Rasul, Ghulam; Tong, Jiang; Ali, Gohar; Cheema, Sohail Babar; Liu, Luliu; Gemmer, Marco; Fischer, Thomas

    2015-04-01

    Finer climate change information on spatial scale is required for impact studies than that presently provided by global or regional climate models. It is especially true for regions like South Asia with complex topography, coastal or island locations, and the areas of highly heterogeneous land-cover. To deal with the situation, an inexpensive method (statistical downscaling) has been adopted. Statistical DownScaling Model (SDSM) employed for downscaling of daily minimum and maximum temperature data of 44 national stations for base time (1961-1990) and then the future scenarios generated up to 2099. Observed as well as Predictors (product of National Oceanic and Atmospheric Administration) data were calibrated and tested on individual/multiple basis through linear regression. Future scenario was generated based on HadCM3 daily data for A2 and B2 story lines. The downscaled data has been tested, and it has shown a relatively strong relationship with the observed in comparison to ECHAM5 data. Generally, the southern half of the country is considered vulnerable in terms of increasing temperatures, but the results of this study projects that in future, the northern belt in particular would have a possible threat of increasing tendency in air temperature. Especially, the northern areas (hosting the third largest ice reserves after the Polar Regions), an important feeding source for Indus River, are projected to be vulnerable in terms of increasing temperatures. Consequently, not only the hydro-agricultural sector but also the environmental conditions in the area may be at risk, in future.

  8. Multi-wavelength Observations of Solar Acoustic Waves Near Active Regions

    Science.gov (United States)

    Monsue, Teresa; Pesnell, Dean; Hill, Frank

    2018-01-01

    Active region areas on the Sun are abundant with a variety of waves that are both acoustically helioseismic and magnetohydrodynamic in nature. The occurrence of a solar flare can disrupt these waves, through MHD mode-mixing or scattering by the excitation of these waves. We take a multi-wavelength observational approach to understand the source of theses waves by studying active regions where flaring activity occurs. Our approach is to search for signals within a time series of images using a Fast Fourier Transform (FFT) algorithm, by producing multi-frequency power map movies. We study active regions both spatially and temporally and correlate this method over multiple wavelengths using data from NASA’s Solar Dynamics Observatory. By surveying the active regions on multiple wavelengths we are able to observe the behavior of these waves within the Solar atmosphere, from the photosphere up through the corona. We are able to detect enhancements of power around active regions, which could be acoustic power halos and of an MHD-wave propagating outward by the flaring event. We are in the initial stages of this study understanding the behaviors of these waves and could one day contribute to understanding the mechanism responsible for their formation; that has not yet been explained.

  9. Generation, language, body mass index, and activity patterns in Hispanic children.

    Science.gov (United States)

    Taverno, Sharon E; Rollins, Brandi Y; Francis, Lori A

    2010-02-01

    The acculturation hypothesis proposes an overall disadvantage in health outcomes for Hispanic immigrants with more time spent living in the U.S., but little is known about how generational status and language may influence Hispanic children's relative weight and activity patterns. To investigate associations among generation and language with relative weight (BMI z-scores), physical activity, screen time, and participation in extracurricular activities (i.e., sports, clubs) in a U.S.-based, nationally representative sample of Hispanic children. Participants included 2012 Hispanic children aged 6-11 years from the cross-sectional 2003 National Survey of Children's Health. Children were grouped according to generational status (first, second, or third), and the primary language spoken in the home (English versus non-English). Primary analyses included adjusted logistic and multinomial logistic regression to examine the relationships among variables; all analyses were conducted between 2008 and 2009. Compared to third-generation, English speakers, first- and second-generation, non-English speakers were more than two times more likely to be obese. Moreover, first-generation, non-English speakers were half as likely to engage in regular physical activity and sports. Both first- and second-generation, non-English speakers were less likely to participate in clubs compared to second- and third-generation, English speakers. Overall, non-English-speaking groups reported less screen time compared to third-generation, English speakers. The hypothesis that Hispanics lose their health protection with more time spent in the U.S. was not supported in this sample of Hispanic children. Copyright 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases

    International Nuclear Information System (INIS)

    Heljasvaara, Ritva; Nyberg, Pia; Luostarinen, Jani; Parikka, Mataleena; Heikkilae, Pia; Rehn, Marko; Sorsa, Timo; Salo, Tuula; Pihlajaniemi, Taina

    2005-01-01

    Endostatin, a potent inhibitor of endothelial cell proliferation, migration, angiogenesis and tumor growth, is proteolytically cleaved from the C-terminal noncollagenous NC1 domain of type XVIII collagen. We investigated the endostatin formation from human collagen XVIII by several MMPs in vitro. The generation of endostatin fragments differing in molecular size (24-30 kDa) and in N-terminal sequences was identified in the cases of MMP-3, -7, -9, -13 and -20. The cleavage sites were located in the protease-sensitive hinge region between the trimerization and endostatin domains of NC1. MMP-1, -2, -8 and -12 did not show any significant activity against the C-terminus of collagen XVIII. The anti-proliferative effect of the 20-kDa endostatin, three longer endostatin-containing fragments generated in vitro by distinct MMPs and the entire NC1 domain, on bFGF-stimulated human umbilical vein endothelial cells was established. The anti-migratory potential of some of these fragments was also studied. In addition, production of endostatin fragments between 24-30 kDa by human hepatoblastoma cells was shown to be due to MMP action on type XVIII collagen. Our results indicate that certain, especially cancer-related, MMP family members can generate biologically active endostatin-containing polypeptides from collagen XVIII and thus, by releasing endostatin fragments, may participate in the inhibition of endothelial cell proliferation, migration and angiogenesis

  11. The THMIS-MTR observation of a active region filament

    Science.gov (United States)

    Zong, W. G.; Tang, Y. H.; Fang, C.

    We present some THMIS-MTR observations of a active region filament on September 4, 2002. The full stokes parameters of the filament were obtained in Hα, CaII 8542 and FeI 6302. By use of the data with high spatial resolution(0.44" per pixel), we probed the fine structure of the filament and gave out the parameters at the barbs' endpoints, including intensity, velocity and longitudinal magnetic field. Comparing the quiescent filament which we have discussed before, we find that: 1)The velocities of the barbs' endpoints are much bigger in the active region filament, the values are more than one thousand meters per second. 2)The barbs' endpoints terminate at the low logitudinal magnetic field in the active region filament, too.

  12. Simultaneous generation of tunable giant dispersive waves in the visible and mid-infrared regions based on photonic crystal fibers

    International Nuclear Information System (INIS)

    Zhang, Lei; Yang, Si-Gang; Chen, Hong-Wei; Chen, Ming-Hua; Xie, Shi-Zhong; Han, Ying

    2013-01-01

    Cherenkov radiation (CR) in both the visible and mid-infrared regions is simultaneously generated experimentally based on a photonic crystal fiber with two zero-dispersion wavelengths. The generation of CR in the visible region originates from solitons located in the anomalous group velocity dispersion (GVD) regime which are perturbed by positive third order dispersion. Conversely, the generation of CR in the mid-infrared region requires that the solitons in the anomalous GVD regime are perturbed by negative third order dispersion. The peak wavelength of the CR in the visible region can be tuned from 498 to 425 nm by increasing the average input pump power from 70 to 400 mW, while the peak wavelength of the CR in the mid-infrared region can be tuned from 1986 to 2279 nm by increasing the average input pump power from 70 to 320 mW. (paper)

  13. Multi-region fuzzy logic controller with local PID controllers for U-tube steam generator in nuclear power plant

    Directory of Open Access Journals (Sweden)

    Puchalski Bartosz

    2015-12-01

    Full Text Available In the paper, analysis of multi-region fuzzy logic controller with local PID controllers for steam generator of pressurized water reactor (PWR working in wide range of thermal power changes is presented. The U-tube steam generator has a nonlinear dynamics depending on thermal power transferred from coolant of the primary loop of the PWR plant. Control of water level in the steam generator conducted by a traditional PID controller which is designed for nominal power level of the nuclear reactor operates insufficiently well in wide range of operational conditions, especially at the low thermal power level. Thus the steam generator is often controlled manually by operators. Incorrect water level in the steam generator may lead to accidental shutdown of the nuclear reactor and consequently financial losses. In the paper a comparison of proposed multi region fuzzy logic controller and traditional PID controllers designed only for nominal condition is presented. The gains of the local PID controllers have been derived by solving appropriate optimization tasks with the cost function in a form of integrated squared error (ISE criterion. In both cases, a model of steam generator which is readily available in literature was used for control algorithms synthesis purposes. The proposed multi-region fuzzy logic controller and traditional PID controller were subjected to broad-based simulation tests in rapid prototyping software - Matlab/Simulink. These tests proved the advantage of multi-region fuzzy logic controller with local PID controllers over its traditional counterpart.

  14. Stability Analysis for Isolated AC Microgrids Based on PV-Active Generators

    DEFF Research Database (Denmark)

    Aldana, Nelson Leonardo Diaz; Coelho, Ernane A. A.; Quintero, Juan Carlos Vasquez

    2015-01-01

    The current trend in isolated microgrids is oriented to distributed renewable energy generators, such as photovoltaic (PV) generators and their corresponding distributed energy storage systems (ESS) as an unit denoted as active generator (PV+ESS). In an isolated microgrid, every distributed...... for all the distributed generators. In particular, ESS’s based on batteries require at least two different mode of charge. As consequence, the topological operation mode of the microgrid is affected by the changes of the operation mode of each distributed generator. Typically, droop control loops are used...... for interconnecting several different distributed generators in parallel to a common bus, whose parameters determine the stability and damping of the microgrid operation. In this paper, a small-signal stability analysis is applied to an isolated AC microgrid composed of (PV+ESS) active generators, regarding three...

  15. Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation.

    LENUS (Irish Health Repository)

    Ni Ainle, Fionnuala

    2009-08-20

    Protamine sulfate is a positively charged polypeptide widely used to reverse heparin-induced anticoagulation. Paradoxically, prospective randomized trials have shown that protamine administration for heparin neutralization is associated with increased bleeding, particularly after cardiothoracic surgery with cardiopulmonary bypass. The molecular mechanism(s) through which protamine mediates this anticoagulant effect has not been defined. In vivo administration of pharmacologic doses of protamine to BALB\\/c mice significantly reduced plasma thrombin generation and prolonged tail-bleeding time (from 120 to 199 seconds). Similarly, in pooled normal human plasma, protamine caused significant dose-dependent prolongations of both prothrombin time and activated partial thromboplastin time. Protamine also markedly attenuated tissue factor-initiated thrombin generation in human plasma, causing a significant decrease in endogenous thrombin potential (41% +\\/- 7%). As expected, low-dose protamine effectively reversed the anticoagulant activity of unfractionated heparin in plasma. However, elevated protamine concentrations were associated with progressive dose-dependent reduction in thrombin generation. To assess the mechanism by which protamine mediates down-regulation of thrombin generation, the effect of protamine on factor V activation was assessed. Protamine was found to significantly reduce the rate of factor V activation by both thrombin and factor Xa. Protamine mediates its anticoagulant activity in plasma by down-regulation of thrombin generation via a novel mechanism, specifically inhibition of factor V activation.

  16. Institutional factor in international economic activity of region and its socio-economic development

    Directory of Open Access Journals (Sweden)

    Elena Leonidovna Andreeva

    2016-12-01

    Full Text Available The article substantiates the impact of the institutional factor on the development of regional international economic relations. The scope of the study is regional international economic activity (IEA, the subject-matter is the role of the institutional factor in its development. The study purpose is to develop a scientific approach for the assessment of the institutional factor impact on the development of region’s international economic relations. The hypothesis is that the targeted efforts of all participants of IEA of the region (business, authorities, local community to strengthen of theese components of the institutional factor, which have a strong influence on the regional socio-economic development. A methodological approach for the assessment of this influenceis developed. It includes determining three elements of IEA institutionalization—agreements, organizations, events. A three-dimensional model is proposed for the coordination of these elements with 3 groups of countries—developed, developing and CIS, including the Eurasian Economic Union, and also with basic indexes characterizing the qualitative and quantitative contribution of region’s IEA into its socio-economic development. This model is tested on the example of the Sverdlovsk region of Russia for 2003–2015. That has allowed to define various kinds of the effects from strenthening the IEA institutional component, which are expressed in the increase of the export of the region, improvement of its investment attractiveness, the diversification of regional economy as well as the the generation of additional jobs and tax flows increase.

  17. Do rural regions benefit from entrepreneurship?

    DEFF Research Database (Denmark)

    Müller, Sabine

    2012-01-01

    This article is about the interplay between rural context and entrepreneurial activity, and its effects on regional development. It focuses on some of the long-term socio-economic benefits entrepreneurship generates in rural regions that go beyond economic growth and job creation....

  18. Emotion at Work: A Contribution to Third-Generation Cultural-Historical Activity Theory

    Science.gov (United States)

    Roth, Wolff-Michael

    2007-01-01

    Second-generation cultural-historical activity theory, which drew its inspiration from Leont'ev's work, constituted an advance over Vygotsky's first-generation theory by explicitly articulating the dialectical relation between individual and collective. As part of an effort to develop third-generation-historical activity theory, I propose in this…

  19. Unwinding motion of a twisted active region filament

    Energy Technology Data Exchange (ETDEWEB)

    Yan, X. L.; Xue, Z. K.; Kong, D. F. [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650011 (China); Liu, J. H. [Department of Physics, Shijiazhuang University, Shijiazhuang 050035 (China); Xu, C. L. [Yunnan Normal University, Kunming 650092 (China)

    2014-12-10

    To better understand the structures of active region filaments and the eruption process, we study an active region filament eruption in active region NOAA 11082 in detail on 2010 June 22. Before the filament eruption, the opposite unidirectional material flows appeared in succession along the spine of the filament. The rising of the filament triggered two B-class flares at the upper part of the filament. As the bright material was injected into the filament from the sites of the flares, the filament exhibited a rapid uplift accompanying the counterclockwise rotation of the filament body. From the expansion of the filament, we can see that the filament consisted of twisted magnetic field lines. The total twist of the filament is at least 5π obtained by using a time slice method. According to the morphology change during the filament eruption, it is found that the active region filament was a twisted flux rope and its unwinding motion was like a solar tornado. We also find that there was a continuous magnetic helicity injection before and during the filament eruption. It is confirmed that magnetic helicity can be transferred from the photosphere to the filament. Using the extrapolated potential fields, the average decay index of the background magnetic fields over the filament is 0.91. Consequently, these findings imply that the mechanism of solar filament eruption could be due to the kink instability and magnetic helicity accumulation.

  20. 20 CFR 627.225 - Employment generating activities.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Employment generating activities. 627.225 Section 627.225 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR GENERAL... chambers of commerce); JTPA staff participation on economic development boards and commissions, and work...

  1. Regional waste treatment facilities with underground monolith disposal for all low-heat-generating nuclear wastes

    International Nuclear Information System (INIS)

    Forsberg, C.W.

    1982-01-01

    An alternative system for treatment and disposal of all ''low-heat-generating'' nuclear wastes from all sources is proposed. The system, Regional Waste Treatment Facilities with Underground Monolith Disposal (RWTF/UMD), integrates waste treatment and disposal operations into single facilities at regional sites. Untreated and/or pretreated wastes are transported from generation sites such as reactors, hospitals, and industries to regional facilities in bulk containers. Liquid wastes are also transported in bulk after being gelled for transport. The untreated and pretreated wastes are processed by incineration, crushing, and other processes at the RWTF. The processed wastes are mixed with cement. The wet concrete mixture is poured into large low-cost, manmade caverns or deep trenches. Monolith dimensions are from 15 to 25 m wide, and 20 to 60 m high and as long as required. This alternative waste system may provide higher safety margins in waste disposal at lower costs

  2. P1-27: Localizing Regions Activated by Surface Gloss in Macaque Visual Cortex by fMRI

    Directory of Open Access Journals (Sweden)

    Gouki Okazawa

    2012-10-01

    Full Text Available Surface properties of objects such as gloss provide important information about the states or materials of objects in our visual experiences. Previous studies have shown that there are cortical regions responding to shapes, colors, faces etc. in the macaque visual cortex. However, we still lack the information about where the surface properties are processed in the macaque visual cortex. In this study, we examined whether there are regions activated by surface gloss, an important surface property, in the macaque visual cortex by using functional magnetic resonance imaging (fMRI. We trained two monkeys to fixate on a small spot on the screen in MRI scanner, while the images of glossy and matte objects were presented. As a control condition for low-level image features, such as spatial frequency or luminance contrast, we generated scrambled images by locally randomizing the luminance phases of images using wavelet filters. By contrasting the responses to glossy images to those to matte and scrambled images, we found the activation in wide regions along the ventral visual pathway including V1, V2, V3, V4, and the posterior part of the inferior temporal (IT cortex. In one monkey, we also found the activations in the central part of IT cortex. In another control experiment, we manipulated the image contrasts and found that the responses in these regions cannot be explained simply by the image contrasts. These results suggest that surface gloss is processed along the ventral pathway and, in the IT cortex there are distinct regions processing surface gloss.

  3. Dependence of hydropower energy generation on forests in the Amazon Basin at local and regional scales.

    Science.gov (United States)

    Stickler, Claudia M; Coe, Michael T; Costa, Marcos H; Nepstad, Daniel C; McGrath, David G; Dias, Livia C P; Rodrigues, Hermann O; Soares-Filho, Britaldo S

    2013-06-04

    Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations' energy growth strategies. Feasibility studies of hydropower plants typically ignore the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local "direct" effects (through changes in ET within the watershed) and the potential regional "indirect" effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world's largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4-8% and 10-12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6-36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry's own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests.

  4. Evolution of management activities and performance of the Point Lepreau Steam Generators

    International Nuclear Information System (INIS)

    Slade, J.; Keating, J.; Gendron, T.

    2007-01-01

    The Point Lepreau steam generators have been in service since 1983 when the plant was commissioned. During the first thirteen years of operation, Point Lepreau steam generator maintenance issues led to 3-4% unplanned plant incapability Steam generator fouling, corrosion, and the introduction of foreign materials during maintenance led to six tube leaks, two unplanned outages, two lengthy extended outages, and degraded thermal performance during this period. In recognition of the link between steam generator maintenance activities and plant performance, improvements to steam generator management activities have been continuously implemented since 1987. This paper reviews the evolution of steam generator management activities at Point Lepreau and the resulting improved trends in performance. Plant incapability from unplanned steam generator maintenance has been close to zero since 1996. The positive trends have provided a strong basis for the management strategies developed for post-refurbishment operation. (author)

  5. Experimental results of the consequences of sodium water reactions at the bottom tube plate region of straight tube steam generators

    International Nuclear Information System (INIS)

    Ruloff, G.

    1990-01-01

    Experience with sodium water reactions has shown, that the course of such a steam generator accident depends strongly on its place in the steam generator. For the EFR steam generators we have to differentiate between: weld region at the upper tube plate (gas space); bundle region; weld region at the bottom tube plate. This paper describes results of a running tests program simulating the bottom tube plate area. One main part of these tests is the investigation of the influence of wastage protection shrouds between the tubes in the weld region to avoid a fast leak propagation and to give time for leak detection and mastering of the accidents. (author). 10 figs, 2 tabs

  6. Determinants of Foreign Technological Activity in German Regions

    DEFF Research Database (Denmark)

    Dettmann, Eva; Lacasa, Iciar Dominguez; Günther, Jutta

    This paper analyses the determinants of spatial distribution of foreign technological activity across 96 German regions (1996-2009). We identify foreign inventive activity by applying the ‘cross-border-ownership concept’ to transnational patent applications. The descriptive analysis shows...

  7. Assessing neutron generator output using neutron activation of silicon

    International Nuclear Information System (INIS)

    Kehayias, Pauli M.; Kehayias, Joseph J.

    2007-01-01

    D-T neutron generators are used for elemental composition analysis and medical applications. Often composition is determined by examining elemental ratios in which the knowledge of the neutron flux is unnecessary. However, the absolute value of the neutron flux is required when the generator is used for neutron activation analysis, to study radiation damage to materials, to monitor the operation of the generator, and to measure radiation exposure. We describe a method for absolute neutron output and flux measurements of low output D-T neutron generators using delayed activation of silicon. We irradiated a series of silicon oxide samples with 14.1 MeV neutrons and counted the resulting gamma rays of the 28 Al nucleus with an efficiency-calibrated detector. To minimize the photon self-absorption effects within the samples, we used a zero-thickness extrapolation technique by repeating the measurement with samples of different thicknesses. The neutron flux measured 26 cm away from the tritium target of a Thermo Electron A-325 D-T generator (Thermo Electron Corporation, Colorado Springs, CO) was 6.2 x 10 3 n/s/cm 2 ± 5%, which is consistent with the manufacturer's specifications

  8. Assessing neutron generator output using neutron activation of silicon

    Energy Technology Data Exchange (ETDEWEB)

    Kehayias, Pauli M. [Body Composition Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 (United States); Kehayias, Joseph J. [Body Composition Laboratory, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111 (United States)]. E-mail: joseph.kehayias@tufts.edu

    2007-08-15

    D-T neutron generators are used for elemental composition analysis and medical applications. Often composition is determined by examining elemental ratios in which the knowledge of the neutron flux is unnecessary. However, the absolute value of the neutron flux is required when the generator is used for neutron activation analysis, to study radiation damage to materials, to monitor the operation of the generator, and to measure radiation exposure. We describe a method for absolute neutron output and flux measurements of low output D-T neutron generators using delayed activation of silicon. We irradiated a series of silicon oxide samples with 14.1 MeV neutrons and counted the resulting gamma rays of the {sup 28}Al nucleus with an efficiency-calibrated detector. To minimize the photon self-absorption effects within the samples, we used a zero-thickness extrapolation technique by repeating the measurement with samples of different thicknesses. The neutron flux measured 26 cm away from the tritium target of a Thermo Electron A-325 D-T generator (Thermo Electron Corporation, Colorado Springs, CO) was 6.2 x 10{sup 3} n/s/cm{sup 2} {+-} 5%, which is consistent with the manufacturer's specifications.

  9. Regional and national radiation protection activities in Egypt

    International Nuclear Information System (INIS)

    Gomaa, M.A.M.

    2008-01-01

    Radiation protection activities in Egypt go back to 1957 where the Egyptian Atomic Energy Commission (EAEC) Law was issued. Radiation protection and civil defense department was one of EAEC eighth departments. Ionizing radiation law was issued in 1960 and its executive regulation in 1962. The main aim of the present work is to through some light on the current radiation protection activities in Egypt. This includes not only the role of governmental organizations but also to the non governmental organizations. Currently a new Nuclear Safety law is understudy. Regional activities such as holding the second all African IRPA regional radiation protection congress which was held in April 2007 and national training and workshops are held regularly through EAEA, AAEA and MERRCAC. (author)

  10. Dynamic Precursors of Flares in Active Region NOAA 10486

    Science.gov (United States)

    Korsós, M. B.; Gyenge, N.; Baranyi, T.; Ludmány, A.

    2015-03-01

    Four different methods are applied here to study the precursors of flare activity in the Active Region NOAA 10486. Two approaches track the temporal behaviour of suitably chosen features (one, the weighted hori- zontal gradient W G M , is the generalized form of the horizontal gradient of the magnetic field, G M ; the other is the sum of the horizontal gradient of the magnetic field, G S , for all sunspot pairs). W G M is a photospheric indicator, that is a proxy measure of magnetic non-potentiality of a specific area of the active region, i.e., it captures the temporal variation of the weighted horizontal gradient of magnetic flux summed up for the region where opposite magnetic polarities are highly mixed. The third one, referred to as the separateness parameter, S l- f , considers the overall morphology. Further, G S and S l- f are photospheric, newly defined quick-look indicators of the polarity mix of the entire active region. The fourth method is tracking the temporal variation of small X-ray flares, their times of succession and their energies observed by the Reuven Ramaty High Energy Solar Spectroscopic Imager instrument. All approaches yield specific pre-cursory signatures for the imminence of flares.

  11. Educational activity on nuclear energy in Aomori region

    International Nuclear Information System (INIS)

    Abe, Katsunori

    2008-01-01

    There are many nuclear industries and research facilities in Aomori Prefecture, Japan. Fuel cycle facilities and a LWR power station are now in operation. Another fuel cycle facilities and power stations will soon be under construction. Fusion research activity, ITER-BA, has started last year. We have launched nuclear-related education and research programs to teach nuclear engineering knowledge and skills to the local students. Hachinohe Institute of Technology is located on Pacific ocean side of Aomori Prefecture close to Rokkasho area, and has six undergraduate departments and three graduate courses. Hitherto, many alumni have engaged in nuclear-related companies in the area. In addition to previous subject on nuclear engineering, a new activity 'Challenge Nuclear-site Experience Program' started in 2007, as one of nuclear educational promotion programs in Japan. The students from various engineering departments learned the status and role of nuclear industries and researches. A curriculum course for nuclear engineering will be ready in 2009 for undergraduate students through various departments. In the summer of 2007, the introductory lesson on nuclear power generation and the technical tour to the power station were carried out for two days. In the autumn, the introductory lesson on nuclear fuel cycle and the tour to fuel cycle facilities were performed for three days, including one day tour to research facilities in the area. Its aim was to let the students recognize the role of regional nuclear activities and the attractiveness of nuclear-related industries. The program was supported by Ministry of Economy, Trade and Industry and was performed in cooperation with Tohoku Electric Power Company, Japan Nuclear Fuel Limited and Japan Atomic Energy Agency. (author)

  12. Antibody complementarity-determining regions (CDRs can display differential antimicrobial, antiviral and antitumor activities.

    Directory of Open Access Journals (Sweden)

    Luciano Polonelli

    Full Text Available BACKGROUND: Complementarity-determining regions (CDRs are immunoglobulin (Ig hypervariable domains that determine specific antibody (Ab binding. We have shown that synthetic CDR-related peptides and many decapeptides spanning the variable region of a recombinant yeast killer toxin-like antiidiotypic Ab are candidacidal in vitro. An alanine-substituted decapeptide from the variable region of this Ab displayed increased cytotoxicity in vitro and/or therapeutic effects in vivo against various bacteria, fungi, protozoa and viruses. The possibility that isolated CDRs, represented by short synthetic peptides, may display antimicrobial, antiviral and antitumor activities irrespective of Ab specificity for a given antigen is addressed here. METHODOLOGY/PRINCIPAL FINDINGS: CDR-based synthetic peptides of murine and human monoclonal Abs directed to: a a protein epitope of Candida albicans cell wall stress mannoprotein; b a synthetic peptide containing well-characterized B-cell and T-cell epitopes; c a carbohydrate blood group A substance, showed differential inhibitory activities in vitro, ex vivo and/or in vivo against C. albicans, HIV-1 and B16F10-Nex2 melanoma cells, conceivably involving different mechanisms of action. Antitumor activities involved peptide-induced caspase-dependent apoptosis. Engineered peptides, obtained by alanine substitution of Ig CDR sequences, and used as surrogates of natural point mutations, showed further differential increased/unaltered/decreased antimicrobial, antiviral and/or antitumor activities. The inhibitory effects observed were largely independent of the specificity of the native Ab and involved chiefly germline encoded CDR1 and CDR2 of light and heavy chains. CONCLUSIONS/SIGNIFICANCE: The high frequency of bioactive peptides based on CDRs suggests that Ig molecules are sources of an unlimited number of sequences potentially active against infectious agents and tumor cells. The easy production and low cost of small

  13. Generation of Unbiased Ionospheric Corrections in Brazilian Region for GNSS positioning based on SSR concept

    Science.gov (United States)

    Monico, J. F. G.; De Oliveira, P. S., Jr.; Morel, L.; Fund, F.; Durand, S.; Durand, F.

    2017-12-01

    Mitigation of ionospheric effects on GNSS (Global Navigation Satellite System) signals is very challenging, especially for GNSS positioning applications based on SSR (State Space Representation) concept, which requires the knowledge of spatial correlated errors with considerable accuracy level (centimeter). The presence of satellite and receiver hardware biases on GNSS measurements difficult the proper estimation of ionospheric corrections, reducing their physical meaning. This problematic can lead to ionospheric corrections biased of several meters and often presenting negative values, which is physically not possible. In this contribution, we discuss a strategy to obtain SSR ionospheric corrections based on GNSS measurements from CORS (Continuous Operation Reference Stations) Networks with minimal presence of hardware biases and consequently physical meaning. Preliminary results are presented on generation and application of such corrections for simulated users located in Brazilian region under high level of ionospheric activity.

  14. Dependence of hydropower energy generation on forests in the Amazon Basin at local and regional scales

    Science.gov (United States)

    Stickler, Claudia M.; Coe, Michael T.; Costa, Marcos H.; Nepstad, Daniel C.; McGrath, David G.; Dias, Livia C. P.; Rodrigues, Hermann O.; Soares-Filho, Britaldo S.

    2013-01-01

    Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations’ energy growth strategies. Feasibility studies of hydropower plants typically ignore the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local “direct” effects (through changes in ET within the watershed) and the potential regional “indirect” effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world’s largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4–8% and 10–12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6–36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry’s own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests. PMID:23671098

  15. Asia Section. Regional Activities Division. Paper.

    Science.gov (United States)

    International Federation of Library Associations, The Hague (Netherlands).

    Two papers on library and information activities in developing nations, particularly in India and other Asian countries, were presented at the 1983 International Federation of Library Associations (IFLA) conference. In "IFLA in Asia: A Review of the Work of the Regional Section for Asia," Edward Lim Huck Tee (Malaysia) describes the low…

  16. An assessment of the regional potential for solar power generation in EU-28

    International Nuclear Information System (INIS)

    Perpiña Castillo, Carolina; Batista e Silva, Filipe; Lavalle, Carlo

    2016-01-01

    In this study we aim at assessing the potential of European regions to solar power generation and its comparison with recent European Union (EU) incentives for the development of this renewable energy source. In this study we use a multi-criteria assessment (MCA) supported by Geographical Information System (GIS) to combine already existing information on solar radiation with other geographical factors such as slope, land use, urban extent and population distribution, as well as proximity to the power grid to generate a suitability map for photovoltaic (PV) power plants across the EU at high spatial resolution. A validation exercise showed that the resulting suitability map is a good predictor of appropriate locations for the deployment of PV power plants. The suitability map was in addition compared to the regional distribution of European funds for development of solar energy from the EU Cohesion policy (2007–2013 programme). Regions were classified according their overall suitability for solar energy power systems and the allocated solar investments by the EU Cohesion policy. This analysis allowed to identify potential mismatches between fund allocations and actual regional suitability for solar energy. It is recommended that future fund allocations take into account suitability criteria for solar energy for optimised results of public policies. - Highlights: • A European suitability map for the solar energy (PV) systems deployment is created. • PV systems can contribute in a sustainable energy production in many regions in EU. • There is no correlation among the EU investment and the suitability in solar energy. • Using marginal lands to place PV systems might avoid the uptake of agricultural land. • Validation of the EU suitability map demonstrated a satisfactory degree of accuracy.

  17. Exoplanet Transits of Stellar Active Regions

    Science.gov (United States)

    Giampapa, Mark S.; Andretta, Vincenzo; Covino, Elvira; Reiners, Ansgar; Esposito, Massimiliano

    2018-01-01

    We report preliminary results of a program to obtain high spectral- and temporal-resolution observations of the neutral helium triplet line at 1083.0 nm in transiting exoplanet systems. The principal objective of our program is to gain insight on the properties of active regions, analogous to solar plages, on late-type dwarfs by essentially using exoplanet transits as high spatial resolution probes of the stellar surface within the transit chord. The 1083 nm helium line is a particularly appropriate diagnostic of magnetized areas since it is weak in the quiet photosphere of solar-type stars but appears strongly in absorption in active regions. Therefore, during an exoplanet transit over the stellar surface, variations in its absorption equivalent width can arise that are functions of the intrinsic strength of the feature in the active region and the known relative size of the exoplanet. We utilized the Galileo Telescope and the GIANO-B near-IR echelle spectrograph to obtain 1083 nm spectra during transits in bright, well-known systems that include HD 189733, HD 209458, and HD 147506 (HAT-P-2). We also obtained simultaneous auxiliary data on the same telescope with the HARPS-N UV-Visible echelle spectrograph. We will present preliminary results from our analysis of the observed variability of the strength of the He I 1083 nm line during transits.Acknowledgements: Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Fundación Galileo Galilei of the INAF (Istituto Nazionale di Astrofisica) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. The NSO is operated by AURA under a cooperative agreement with the NSF.

  18. Extreme Trust Region Policy Optimization for Active Object Recognition.

    Science.gov (United States)

    Liu, Huaping; Wu, Yupei; Sun, Fuchun; Huaping Liu; Yupei Wu; Fuchun Sun; Sun, Fuchun; Liu, Huaping; Wu, Yupei

    2018-06-01

    In this brief, we develop a deep reinforcement learning method to actively recognize objects by choosing a sequence of actions for an active camera that helps to discriminate between the objects. The method is realized using trust region policy optimization, in which the policy is realized by an extreme learning machine and, therefore, leads to efficient optimization algorithm. The experimental results on the publicly available data set show the advantages of the developed extreme trust region optimization method.

  19. Inertial effects on the stress generation of active fluids

    Science.gov (United States)

    Takatori, S. C.; Brady, J. F.

    2017-09-01

    Suspensions of self-propelled bodies generate a unique mechanical stress owing to their motility that impacts their large-scale collective behavior. For microswimmers suspended in a fluid with negligible particle inertia, we have shown that the virial swim stress is a useful quantity to understand the rheology and nonequilibrium behaviors of active soft matter systems. For larger self-propelled organisms such as fish, it is unclear how particle inertia impacts their stress generation and collective movement. Here we analyze the effects of finite particle inertia on the mechanical pressure (or stress) generated by a suspension of self-propelled bodies. We find that swimmers of all scales generate a unique swim stress and Reynolds stress that impact their collective motion. We discover that particle inertia plays a similar role as confinement in overdamped active Brownian systems, where the reduced run length of the swimmers decreases the swim stress and affects the phase behavior. Although the swim and Reynolds stresses vary individually with the magnitude of particle inertia, the sum of the two contributions is independent of particle inertia. This points to an important concept when computing stresses in computer simulations of nonequilibrium systems: The Reynolds and the virial stresses must both be calculated to obtain the overall stress generated by a system.

  20. Non-Relative Value Unit-Generating Activities Represent One-Fifth of Academic Neuroradiologist Productivity.

    Science.gov (United States)

    Wintermark, M; Zeineh, M; Zaharchuk, G; Srivastava, A; Fischbein, N

    2016-07-01

    A neuroradiologist's activity includes many tasks beyond interpreting relative value unit-generating imaging studies. Our aim was to test a simple method to record and quantify the non-relative value unit-generating clinical activity represented by consults and clinical conferences, including tumor boards. Four full-time neuroradiologists, working an average of 50% clinical and 50% academic activity, systematically recorded all the non-relative value unit-generating consults and conferences in which they were involved during 3 months by using a simple, Web-based, computer-based application accessible from smartphones, tablets, or computers. The number and type of imaging studies they interpreted during the same period and the associated relative value units were extracted from our billing system. During 3 months, the 4 neuroradiologists working an average of 50% clinical activity interpreted 4241 relative value unit-generating imaging studies, representing 8152 work relative value units. During the same period, they recorded 792 non-relative value unit-generating study reviews as part of consults and conferences (not including reading room consults), representing 19% of the interpreted relative value unit-generating imaging studies. We propose a simple Web-based smartphone app to record and quantify non-relative value unit-generating activities including consults, clinical conferences, and tumor boards. The quantification of non-relative value unit-generating activities is paramount in this time of a paradigm shift from volume to value. It also represents an important tool for determining staffing levels, which cannot be performed on the basis of relative value unit only, considering the importance of time spent by radiologists on non-relative value unit-generating activities. It may also influence payment models from medical centers to radiology departments or practices. © 2016 by American Journal of Neuroradiology.

  1. Inhibition of [gamma]-endorphin generating endopeptidase activity of rat brain by peptides: Structure activity relationship

    NARCIS (Netherlands)

    Lebouille, J.L.M.; Visser, W.H.; Hendriks, R.W.; Nispen, J.W. van; Greven, H.M.; Burbach, J.P.H.

    1985-01-01

    Gamma-Endorphin generating endopeptidase (gammaEGE) activity is an enzyme activity which converts beta-endorphin into gamma-endorphin and beta-endorphin-(18–31). The inhibitory potency on gammaEGE activity of neuropeptides and analogues or fragments of neuropeptides was tested. Dynorphin-(1–13)

  2. Cerebellar activation in verb generation. Activation study with positron emission tomography in normal subjects

    Energy Technology Data Exchange (ETDEWEB)

    Yokoyama, Eriko [Inst. for Rehabilitation and Mental Health, Kyowa, Akita (Japan); Kanno, Iwao; Sadato, Norihiro; Senda, Michio; Fujita, Hideaki; Nagata, Ken

    1999-06-01

    To investigate the role of cerebellum in language function, we used the silent verb generation task in PET activation study. Subjects were 11 right-handed, healthy men with the mean age of 24.3. We used two experimental conditions, resting state and verb generation, and measured cerebral blood flow (CBF) alternately and repeatedly, three times for each condition. In the verb generation task, the subject was asked to silently think of as many verbs associated with auditorily given noun as he could. The subtraction image between verb generation and resting state showed activation foci at the left inferior to middle frontal lobe as well as temporal lobe in the supratentorium, consistent with previous studies. In the infratentorium, there were significant foci at bilateral cerebellar hemisphere and brain stem, which was predominantly seen over the right cerebellum. Activations were seen in the superior-lateral part of the right cerebellar hemisphere including the right dentate nucleus, and in the inferior-lateral part of the left cerebellar hemisphere. The amount of CBF increase by the task as compared with the resting condition in the upper cerebellum showed an increasing trend from the first to the third measurement. The present results suggest specific roles of the cerebellum in word retrieval as well as the practice-related changes during verbal learning. (author)

  3. Cerebellar activation in verb generation. Activation study with positron emission tomography in normal subjects

    International Nuclear Information System (INIS)

    Yokoyama, Eriko; Kanno, Iwao; Sadato, Norihiro; Senda, Michio; Fujita, Hideaki; Nagata, Ken

    1999-01-01

    To investigate the role of cerebellum in language function, we used the silent verb generation task in PET activation study. Subjects were 11 right-handed, healthy men with the mean age of 24.3. We used two experimental conditions, resting state and verb generation, and measured cerebral blood flow (CBF) alternately and repeatedly, three times for each condition. In the verb generation task, the subject was asked to silently think of as many verbs associated with auditorily given noun as he could. The subtraction image between verb generation and resting state showed activation foci at the left inferior to middle frontal lobe as well as temporal lobe in the supratentorium, consistent with previous studies. In the infratentorium, there were significant foci at bilateral cerebellar hemisphere and brain stem, which was predominantly seen over the right cerebellum. Activations were seen in the superior-lateral part of the right cerebellar hemisphere including the right dentate nucleus, and in the inferior-lateral part of the left cerebellar hemisphere. The amount of CBF increase by the task as compared with the resting condition in the upper cerebellum showed an increasing trend from the first to the third measurement. The present results suggest specific roles of the cerebellum in word retrieval as well as the practice-related changes during verbal learning. (author)

  4. Cerebellum engages in automation of verb-generation skill.

    Science.gov (United States)

    Yang, Zhi; Wu, Paula; Weng, Xuchu; Bandettini, Peter A

    2014-03-01

    Numerous studies have shown cerebellar involvement in item-specific association, a form of explicit learning. However, very few have demonstrated cerebellar participation in automation of non-motor cognitive tasks. Applying fMRI to a repeated verb-generation task, we sought to distinguish cerebellar involvement in learning of item-specific noun-verb association and automation of verb generation skill. The same set of nouns was repeated in six verb-generation blocks so that subjects practiced generating verbs for the nouns. The practice was followed by a novel block with a different set of nouns. The cerebellar vermis (IV/V) and the right cerebellar lobule VI showed decreased activation following practice; activation in the right cerebellar Crus I was significantly lower in the novel challenge than in the initial verb-generation task. Furthermore, activation in this region during well-practiced blocks strongly correlated with improvement of behavioral performance in both the well-practiced and the novel blocks, suggesting its role in the learning of general mental skills not specific to the practiced noun-verb pairs. Therefore, the cerebellum processes both explicit verbal associative learning and automation of cognitive tasks. Different cerebellar regions predominate in this processing: lobule VI during the acquisition of item-specific association, and Crus I during automation of verb-generation skills through practice.

  5. The neural circuits that generate tics in Tourette's syndrome.

    Science.gov (United States)

    Wang, Zhishun; Maia, Tiago V; Marsh, Rachel; Colibazzi, Tiziano; Gerber, Andrew; Peterson, Bradley S

    2011-12-01

    The purpose of this study was to examine neural activity and connectivity within cortico-striato-thalamo-cortical circuits and to reveal circuit-based neural mechanisms that govern tic generation in Tourette's syndrome. Functional magnetic resonance imaging data were acquired from 13 individuals with Tourette's syndrome and 21 healthy comparison subjects during spontaneous or simulated tics. Independent component analysis with hierarchical partner matching was used to isolate neural activity within functionally distinct regions of cortico-striato-thalamo-cortical circuits. Granger causality was used to investigate causal interactions among these regions. The Tourette's syndrome group exhibited stronger neural activity and interregional causality than healthy comparison subjects throughout all portions of the motor pathway, including the sensorimotor cortex, putamen, pallidum, and substantia nigra. Activity in these areas correlated positively with the severity of tic symptoms. Activity within the Tourette's syndrome group was stronger during spontaneous tics than during voluntary tics in the somatosensory and posterior parietal cortices, putamen, and amygdala/hippocampus complex, suggesting that activity in these regions may represent features of the premonitory urges that generate spontaneous tic behaviors. In contrast, activity was weaker in the Tourette's syndrome group than in the healthy comparison group within portions of cortico-striato-thalamo-cortical circuits that exert top-down control over motor pathways (the caudate and anterior cingulate cortex), and progressively less activity in these regions accompanied more severe tic symptoms, suggesting that faulty activity in these circuits may result in their failure to control tic behaviors or the premonitory urges that generate them. Our findings, taken together, suggest that tics are caused by the combined effects of excessive activity in motor pathways and reduced activation in control portions of cortico

  6. Fast neutron activation analysis by means of low voltage neutron generator

    Directory of Open Access Journals (Sweden)

    M.E. Medhat

    Full Text Available A description of D-T neutron generator (NG is presented. This machine can be used for fast neutron activation analysis applied to determine some selected elements, especially light elements, in different materials. Procedure of neutron flux determination and efficiency calculation is described. Examples of testing some Egyptian natural cosmetics are given. Keywords: Neutron generator, Fast neutron activation analysis, Elemental analysis

  7. Active Generations: An Intergenerational Approach to Preventing Childhood Obesity

    Science.gov (United States)

    Werner, Danilea; Teufel, James; Holtgrave, Peter L.; Brown, Stephen L.

    2012-01-01

    Background: Over the last 3 decades, US obesity rates have increased dramatically as more children and more adults become obese. This study explores an innovative program, Active Generations, an intergenerational nutrition education and activity program implemented in out-of-school environments (after school and summer camps). It utilizes older…

  8. Pulsed neutron generator for use with pulsed neutron activation techniques

    International Nuclear Information System (INIS)

    Rochau, G.E.

    1980-01-01

    A high-output, transportable, pulsed neutron generator has been developed by Sandia National Laboratories for use with Pulsed Neutron Activation (PNA) techniques. The PNA neutron generator generates > 10 10 14 MeV D-T neutrons in a 1.2 millisecond pulse. Each operation of the unit will produce a nominal total neutron output of 1.2 x 10 10 neutrons. The generator has been designed to be easily repaired and modified. The unit requires no additional equipment for operation or measurement of output

  9. Forecasting municipal solid waste generation in a fast-growing urban region with system dynamics modeling

    International Nuclear Information System (INIS)

    Dyson, Brian; Chang, N.-B.

    2005-01-01

    Both planning and design of municipal solid waste management systems require accurate prediction of solid waste generation. Yet achieving the anticipated prediction accuracy with regard to the generation trends facing many fast-growing regions is quite challenging. The lack of complete historical records of solid waste quantity and quality due to insufficient budget and unavailable management capacity has resulted in a situation that makes the long-term system planning and/or short-term expansion programs intangible. To effectively handle these problems based on limited data samples, a new analytical approach capable of addressing socioeconomic and environmental situations must be developed and applied for fulfilling the prediction analysis of solid waste generation with reasonable accuracy. This study presents a new approach - system dynamics modeling - for the prediction of solid waste generation in a fast-growing urban area based on a set of limited samples. To address the impact on sustainable development city wide, the practical implementation was assessed by a case study in the city of San Antonio, Texas (USA). This area is becoming one of the fastest-growing regions in North America due to the economic impact of the North American Free Trade Agreement (NAFTA). The analysis presents various trends of solid waste generation associated with five different solid waste generation models using a system dynamics simulation tool - Stella[reg]. Research findings clearly indicate that such a new forecasting approach may cover a variety of possible causative models and track inevitable uncertainties down when traditional statistical least-squares regression methods are unable to handle such issues

  10. Spatially resolved X-ray spectra of coronal active regions

    International Nuclear Information System (INIS)

    Catura, R.C.; Acton, L.W.; Joki, E.G.; Rapley, C.G.; Culhane, J.L.

    1975-01-01

    X-ray spectra from a number of coronal active regions were obtained during ATM support rocket flights carried out by the Lockheed group on June 11 and December 19, 1973. Multi-grid collimators were used to provide fields of view of 40ins. diameter and 90ins. diameter for a number of scanning crystal spectrometers and a bent crystal spectrometer which employed a position sensitive proportional counter to register the diffracted spectrum. A solar image was produced on film and on a TV camera on board the rocket with the aid of a 1 A Hα filter. A small part of the X-ray collimator was used to generate a multiple spot diffraction pattern which was superimposed on the Hα image and the composite picture was transmitted to the ground. Pre-launch calibrations allowed the spot corresponding to the X-ray collimator axis to be identified and so the collimator pointing direction on the solar disc was controlled from the ground by means of commands sent to the rocket. (Auth.)

  11. DIVERGENT HORIZONTAL SUB-SURFACE FLOWS WITHIN ACTIVE REGION 11158

    Energy Technology Data Exchange (ETDEWEB)

    Jain, Kiran; Tripathy, S. C.; Hill, F., E-mail: kjain@nso.edu, E-mail: stripathy@nso.edu, E-mail: fhill@nso.edu [National Solar Observatory, 950 N Cherry Avenue, Tucson, AZ 85719 (United States)

    2015-07-20

    We measure the horizontal subsurface flow in a fast emerging active region (AR; NOAA 11158) using the ring-diagram technique and the Helioseismic and Magnetic Imager high spatial resolution Dopplergrams. This AR had a complex magnetic structure and displayed significant changes in morphology during its disk passage. Over a period of six days from 2011 February 11 to 16, the temporal variation in the magnitude of the total velocity is found to follow the trend of magnetic field strength. We further analyze regions of individual magnetic polarity within AR 11158 and find that the horizontal velocity components in these sub-regions have significant variation with time and depth. The leading and trailing polarity regions move faster than the mixed-polarity region. Furthermore, both zonal and meridional components have opposite signs for trailing and leading polarity regions at all depths showing divergent flows within the AR. We also find a sharp decrease in the magnitude of total horizontal velocity in deeper layers around major flares. It is suggested that the re-organization of magnetic fields during flares, combined with the sunspot rotation, decreases the magnitude of horizontal flows or that the flow kinetic energy has been converted into the energy released by flares. After the decline in flare activity and sunspot rotation, the flows tend to follow the pattern of magnetic activity. We also observe less variation in the velocity components near the surface but these tend to increase with depth, further demonstrating that the deeper layers are more affected by the topology of ARs.

  12. Ground-based acoustic parametric generator impact on the atmosphere and ionosphere in an active experiment

    Directory of Open Access Journals (Sweden)

    Y. G. Rapoport

    2017-01-01

    Full Text Available We develop theoretical basics of active experiments with two beams of acoustic waves, radiated by a ground-based sound generator. These beams are transformed into atmospheric acoustic gravity waves (AGWs, which have parameters that enable them to penetrate to the altitudes of the ionospheric E and F regions where they influence the electron concentration of the ionosphere. Acoustic waves are generated by the ground-based parametric sound generator (PSG at the two close frequencies. The main idea of the experiment is to design the output parameters of the PSG to build a cascade scheme of nonlinear wave frequency downshift transformations to provide the necessary conditions for their vertical propagation and to enable penetration to ionospheric altitudes. The PSG generates sound waves (SWs with frequencies f1 = 600 and f2 = 625 Hz and large amplitudes (100–420 m s−1. Each of these waves is modulated with the frequency of 0.016 Hz. The novelty of the proposed analytical–numerical model is due to simultaneous accounting for nonlinearity, diffraction, losses, and dispersion and inclusion of the two-stage transformation (1 of the initial acoustic waves to the acoustic wave with the difference frequency Δf = f2 − f1 in the altitude ranges 0–0.1 km, in the strongly nonlinear regime, and (2 of the acoustic wave with the difference frequency to atmospheric acoustic gravity waves with the modulational frequency in the altitude ranges 0.1–20 km, which then reach the altitudes of the ionospheric E and F regions, in a practically linear regime. AGWs, nonlinearly transformed from the sound waves, launched by the two-frequency ground-based sound generator can increase the transparency of the ionosphere for the electromagnetic waves in HF (MHz and VLF (kHz ranges. The developed theoretical model can be used for interpreting an active experiment that includes the PSG impact on the atmosphere–ionosphere system

  13. Contribution of generative leisure activities to cognitive function in elderly Sri Lankan adults.

    Science.gov (United States)

    Maselko, Joanna; Sebranek, Matthew; Mun, Mirna H; Perera, Bilesha; Ahs, Jill; Ostbye, Truls

    2014-09-01

    To examine the unique contribution of generative leisure activities, defined as activities motivated by a concern for others and a need to contribute something to the next generation. Cross-sectional survey. Peri-urban and rural area in southern Sri Lanka. Community-dwelling adults aged 60 and older (N = 252). The main predictors were leisure activities, grouped into generative, social, or solitary. The main outcome was cognitive function, assessed using the Montreal Cognitive Assessment (MoCA) and the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE). More-frequent engagement in generative leisure activities was associated with higher levels of cognitive function, independent of the effect of other social and solitary leisure activities. In a fully adjusted model combining all three leisure activities, generative activities independently predicted cognitive function as measured using the MoCA (β = 0.47, 95% confidence interval (CI) = 0.11-0.83) and the IQCODE (β = -0.81, 95% CI = -1.54 to -0.09). In this combined model, solitary activities were also independently associated with slower cognitive decline using the MoCA (β = 0.40, 95% CI = 0.16-0.64) but not the IQCODE (β = -0.38, 95% CI = -0.88-0.12); the association with social activities did not reach statistical significance with either measure. These associations did not differ meaningfully according to sex. Generative leisure activities are a promising area for the development of interventions aimed at reducing cognitive decline in elderly adults. © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.

  14. Kinematic model of some types of motion of matter in active regions

    International Nuclear Information System (INIS)

    Platov, Yu.V.

    1983-01-01

    The kinematics of matter motion in variable magnetic fields of active regions on the Sun in the MHD approximation of a strong field and cold plasma is investigated. It is shown that the variation of sunspot magnetic moments lead to the development of different active phenomena in the solar atmosphere. The development of such phenomena at first can occur at the phase of active region growth, when new sunspots together with developed sunspots emerge in an active region or relative motions take place in a sunspot group

  15. Cooling Active Region Loops Observed With SXT and TRACE

    OpenAIRE

    Winebarger, Amy R.; Warren, Harry P.

    2005-01-01

    An Impulsive Heating Multiple Strand (IHMS) Model is able to reproduce the observational characteristics of EUV (~ 1 MK) active region loops. This model implies that some of the loops must reach temperatures where X-ray filters are sensitive (> 2.5 MK) before they cool to EUV temperatures. Hence, some bright EUV loops must be preceded by bright X-ray loops. Previous analysis of X-ray and EUV active region observations, however, have concluded that EUV loops are not preceded by X-ray loops. In...

  16. GIS-based approach for potential analysis of solar PV generation at the regional scale: A case study of Fujian Province

    International Nuclear Information System (INIS)

    Sun, Yan-wei; Hof, Angela; Wang, Run; Liu, Jian; Lin, Yan-jie; Yang, De-wei

    2013-01-01

    Spatial variation of solar energy is crucial for the estimation of the regional potential and selection of construction location. This paper presents a case study of using high resolution grid map of solar radiation combined with the other restriction factors to evaluate the comprehensive potential analysis of solar PV generation at the regional scale, in order to present a framework of decision support tool for solar energy management in a regional area. The cost of PV generation is calculated based on the geographical distribution of technical potential. Moreover, geospatial supply curve (GSC) is employed to portray the evolution of available potential of photovoltaics (PV) generation with the increase of the generation cost. By integrating the economic evaluation variables of net present value and simple payback period, grid-based economic feasibility of PV generation project is then carried out under two feed-in-tariff scenarios. Finally, total CO 2 reduction potential and its spatial distribution in the study area are calculated. The results confirm that PV technology provides high potential for roof-top application and large-scale PV stations. Additionally, determining a reasonable feed-in tariff is essential for expanding the application of solar PV energy. The findings improve understanding of regional renewable energy strategies and the supply/demand assessment. - Highlights: • We developed a grid-based comprehensive potential analysis framework of solar energy at the regional scale. • We evaluated the technical potential of solar PV generation. • We calculated the cost of PV generation and got the geospatial supply curve (GSC) of Fujian Province. • PV technology provides high potential for roof-top application and large-scale PV stations. • Determining a reasonable feed-in tariff is essential for expanding the application of solar PV energy

  17. The impact of carbon taxes or allowances on the electric generation market in the Ohio and ECAR region

    International Nuclear Information System (INIS)

    Hadley, S.W.

    1998-07-01

    The North American electricity grid is separated into 11 regional reliability councils, collectively called the North American Electric Reliability Council (NERC). The East Central Area Reliability Coordination Agreement (ECAR) is the reliability council that covers Ohio and Indiana, along with parts of Kentucky, Illinois, Maryland, Michigan, Pennsylvania, Virginia, and West Virginia. Ohio and the rest of the ECAR region rely more heavily on coal-fired generation than any other US region. The purpose of this report is to study the effect of carbon reduction policies on the cost and price of generation in the ECAR region, with an emphasis on Ohio. In order to do that, the author modeled the possible electric generation system for the ECAR and Ohio region for the year 2010 using a model developed at Oak Ridge National Laboratory called the Oak Ridge Competitive Electric Dispatch model (ORCED). He let the model optimize the system based on various factors and carbon reduction policies to understand their impact. He then used the electricity prices and assumed demand elasticities to change the demands while also requiring all power plants to be profitable. The author discusses the different potential policies for carbon reduction and issues involving a restructured market; describes the model used for this analysis, the ECAR electricity sector, and the establishment of a base case; and describes the results of applying various carbon emission reduction approaches to the region. 14 figs., 5 tabs

  18. Activization of the state policy on euro-regional cooperation in the sphere of the interstate regional governance

    Directory of Open Access Journals (Sweden)

    V. I. Pak

    2016-09-01

    Research objective is the justification of the need of activization of the state policy on Euro-regional cooperation in the sphere of the interstate regional governance. During the research it is recognized that the realization of the state policy on the basis of the considered principles, tools, functions, factors and methods has to execute a main objective of the interstate regional control which is exercised in the sphere of Euro-regional cooperation and to promote adjustment of close mutually beneficial relations of Ukraine and neighboring states, to increase competitiveness of the Ukrainian territories and the most effective use of capacity of the Ukrainian regions in the course of activity of Euro-regions. Finally, such state policy has to be focused on the maintenance of the sufficient standard of living of the population, on ensuring integrity and unity of the social and economic space of the country, on formation of the conditions of sustainable and industrial and innovative development of regions, which will provide its harmonious integration into the European environment.

  19. Generation of radicals and antimalarial activity of dispiro-1,2,4-trioxolanes

    Science.gov (United States)

    Denisov, E. T.; Denisova, T. G.

    2013-01-01

    The kinetic schemes of the intramolecular oxidation of radicals generated from substituted dispiro-1,2,4-trioxolanes (seven compounds) in the presence of Fe2+ and oxygen were built. Each radical reaction was defined in terms of enthalpy, activation energy, and rate constant. The kinetic characteristics were calculated by the intersecting parabolas method. The competition between the radical reactions was considered. The entry of radicals generated by each compound into the volume was calculated. High antimalarial activity was found for 1,2,4-trioxolanes, which generated hydroxyl radicals. The structural features of trioxolanes responsible for the generation of hydroxyl radicals were determined.

  20. Geometry of Hα active region loops observed on the solar disk

    International Nuclear Information System (INIS)

    Chuan-le, C.; Loughhead, R.E.

    1983-01-01

    Plasma loops are the dominant structures in the higher levels of the Sun's atmosphere above active regions. A geometrical technique has been used to reconstruct the true shapes of two large dark loops of the type ordinarily found in active regions in the absence of flares

  1. Contact system activation and high thrombin generation in hyperthyroidism.

    Science.gov (United States)

    Kim, Namhee; Gu, Ja-Yoon; Yoo, Hyun Ju; Han, Se Eun; Kim, Young Il; Nam-Goong, Il Sung; Kim, Eun Sook; Kim, Hyun Kyung

    2017-05-01

    Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extracellular traps (NET) has emerged as an important trigger of thrombosis, we hypothesized that the contact system is activated along with active NET formation in hyperthyroidism and that their markers correlate with disease severity. In 61 patients with hyperthyroidism and 40 normal controls, the levels of coagulation factors (fibrinogen, and factor VII, VIII, IX, XI and XII), D-dimer, thrombin generation assay (TGA) markers, NET formation markers (histone-DNA complex, double-stranded DNA and neutrophil elastase) and contact system markers (activated factor XII (XIIa), high-molecular-weight kininogen (HMWK), prekallikrein and bradykinin) were measured. Patients with hyperthyroidism showed higher levels of fibrinogen (median (interquartile range), 315 (280-344) vs 262 (223-300), P  = 0.001), D-dimer (103.8 (64.8-151.5) vs 50.7 (37.4-76.0), P  hyperthyroidism's contribution to coagulation and contact system activation. Free T4 was significantly correlated with factors VIII and IX, D-dimer, double-stranded DNA and bradykinin. This study demonstrated that contact system activation and abundant NET formation occurred in the high thrombin generation state in hyperthyroidism and were correlated with free T4 level. © 2017 European Society of Endocrinology.

  2. Waste production and regional growth of marine activities an econometric model.

    Science.gov (United States)

    Bramati, Maria Caterina

    2016-11-15

    Coastal regions are characterized by intense human activity and climatic pressures, often intensified by competing interests in the use of marine waters. To assess the effect of public spending on the regional economy, an econometric model is here proposed. Not only are the regional investment and the climatic risks included in the model, but also variables related to the anthropogenic pressure, such as population, economic activities and waste production. Feedback effects of economic and demographic expansion on the pollution of coastal areas are also considered. It is found that dangerous waste increases with growing shipping and transportation activities and with growing population density in non-touristic coastal areas. On the other hand, the amount of non-dangerous wastes increases with marine mining, defense and offshore energy production activities. However, lower waste production occurs in areas where aquaculture and touristic industry are more exploited, and accompanied by increasing regional investment in waste disposal. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Venture capital: Generator of growth of SME investment activities

    Directory of Open Access Journals (Sweden)

    Dželetović Milenko

    2017-01-01

    Full Text Available The aim of the paper is to point out the importance and role of venture capital in creation of new values based on the knowledge economy. By reviewing relevant literature about venture capital, this paper presents the importance of the venture capital investments in innovative activities of SMEs that have an impact on economic growth. Pointing to the importance and quantifying the overall effects of venture capital investments, will be used the overview and trends in venture capital investments in the sectors of economy in Europe which generate a larger number of patents. According to data during the period of 2007 - 2015 will be defined venture capital investments and number of registered patents in the sectors of the knowledge economy. Empirical analysis indicated that the venture investments in the sectors of the knowledge economy generated more patents in those sectors. In addition, the paper analyzes the venture capital investment and innovation activities of SMEs, which are reflected in patent activities, where the result is a correlation between these activities in the European economies.

  4. Self-sufficiency in power generation for a hamlet in the Allgaeu region

    Energy Technology Data Exchange (ETDEWEB)

    Naumann, L.; Kusche, K.

    A secluded farmhouse in the Allgaeu region was to be rebuilt into a residential house and had to be equipped with its own power supply and generating system. A combination of solar collectors and solar generators and a cogeneration plant with under 5 kW power output and an additionally installed tiled stove make up the energy concept for the house. Only a small amount of non-renewable energy in the form of liquid gas is required for a the family of five. The electricity is supplied by a gas motor cogeneration plant and 20 solar modules. On sunny days the gas-fuelled power generator is switched off and the house is supplied by the solar installations only. 12 batteries store the power. Space heating consists of a combination of a gas-fired low temperature heating system and a hot-air tiled stove. Service water heating is taken care of by ten flat collectors connected with one storage unit which can be supplied with extra heat from the gas heater, if requested.

  5. Turn emergency generators into dollars

    International Nuclear Information System (INIS)

    Sheahen, T.P.; Stegen, G.R.

    1997-01-01

    The concept of distributed, dispatchable power generation is essentially the reverse of interruptible service. It can be understood by regarding both power and money as vectors: when the direction of the power flow switches, so does the direction of the money flow. At a signal given by the utility, a factory activates its emergency generating system and briefly becomes an independent power producer (IPP), feeding power into a local region of the grid. Upon receipt of another signal, it retires from that role. It may, however, continue to generate power for its own use

  6. Effect of magnetic activity on plasma bubbles over equatorial and low-latitude regions in East Asia

    Directory of Open Access Journals (Sweden)

    G. Li

    2009-01-01

    Full Text Available The dependence of plasma bubble occurrence in the eveningside ionosphere, with magnetic activity during the period years 2001–2004, is studied here based on the TEC observations gathered by ground-based GPS receivers which are located in the equatorial and low-latitude regions in East Asia. The observed plasma bubbles consist of the plasma-bubble events in the equatorial (stations GUAM, PIMO and KAYT, and low-latitude regions (stations WUHN, DAEJ and SHAO. It is shown that most equatorial plasma-bubble events commence at 20:00 LT, and may last for >60 min. The magnetic activity appears to suppress the generation of equatorial plasma bubbles with a time delay of more than 3 h (4–9 h. While in the low-latitude regions, most plasma-bubble events commence at about 23:00 LT and last for <45 min. The best correlation between Kp and low-latitude plasma-bubble occurrence is found with an 8–9 h delay, a weak correlation exists for time delays of 6–7 h. This probably indicates that over 3 h delayed disturbance dynamo electric fields obviously inhibit the development of plasma bubbles in the pre-midnight sector.

  7. The Contribution of Generative Leisure Activities to Cognitive Function among Sri Lankan Elderly

    Science.gov (United States)

    Maselko, Joanna; Sebranek, Matthew; Mun, Mirna Hodzic; Perera, Bilesha; Ahs, Jill; Østbye, Truls

    2014-01-01

    OBJECTIVES Although a substantive body of research has shown a protective association between leisure activities and cognitive function, consistent evidence is lacking about which specific types of activities should be promoted. The objective of this analysis was to examine the unique contribution of generative leisure activities, defined as activities motivated by “a concern for others and a need to contribute something to the next generation” (Erikson). DESIGN Cross-sectional survey. SETTING Peri-urban and rural area in southern Sri Lanka. PARTICIPANTS Community dwelling adults aged 60+ (n=252). MEASUREMENTS Main predictors were leisure activities grouped into generative, social, or solitary. Main outcome was cognitive function assessed with Montreal Cognitive Assessment (MoCA) and the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE). RESULTS We found that more frequent engagement in generative leisure activities was associated with higher levels of cognitive function, independent of the impact of other social and solitary leisure activities. In a fully adjusted model combining all three leisure activities, generative activities independently predicted cognitive function as measured with the MoCA (β =0.47 (0.11 to 0.83) and the IQCODE (β = -0.81 (-1.54 to -0.09)). In this combined model, solitary activities were also independently associated with slower cognitive decline with the MoCA (β =0.40 (0.16, 0.64), but not with IQCODE (β =-0.38 (-0.88, 0.12)); the association with social activities did not reach statistical significance with either measure. These associations did not differ meaningfully by gender. CONCLUSION Generative leisure activities are a promising area for the development of interventions aimed at reducing cognitive decline among the elderly. PMID:25139145

  8. New generation non-stationary portable neutron generators for biophysical applications of Neutron Activation Analysis.

    Science.gov (United States)

    Marchese, N; Cannuli, A; Caccamo, M T; Pace, C

    2017-01-01

    Neutron sources are increasingly employed in a wide range of research fields. For some specific purposes an alternative to existing large-scale neutron scattering facilities, can be offered by the new generation of portable neutron devices. This review reports an overview for such recently available neutron generators mainly addressed to biophysics applications with specific reference to portable non-stationary neutron generators applied in Neutron Activation Analysis (NAA). The review reports a description of a typical portable neutron generator set-up addressed to biophysics applications. New generation portable neutron devices, for some specific applications, can constitute an alternative to existing large-scale neutron scattering facilities. Deuterium-Deuterium pulsed neutron sources able to generate 2.5MeV neutrons, with a neutron yield of 1.0×10 6 n/s, a pulse rate of 250Hz to 20kHz and a duty factor varying from 5% to 100%, when combined with solid-state photon detectors, show that this kind of compact devices allow rapid and user-friendly elemental analysis. "This article is part of a Special Issue entitled "Science for Life" Guest Editor: Dr. Austen Angell, Dr. Salvatore Magazù and Dr. Federica Migliardo". Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Solar activity effects in the ionospheric D region

    Directory of Open Access Journals (Sweden)

    A. D. Danilov

    1998-12-01

    Full Text Available Variations in the D-region electron concentration within the solar activity cycle are considered. It is demonstrated that conclusions of various authors, who have analyzed various sets of experimental data on [e], differ significantly. The most reliable seem to be the conclusions based on analysis of the [e] measurements carried out by the Faraday rotation method and on the theoretical concepts on the D-region photochemistry. Possible QBO effects in the relation of [e] to solar activity are considered and an assumption is made that such effects may be the reason for the aforementioned disagreement in conclusions on the [e] relation to solar indices.Key words. Atmospheric composition and structure · Ion chemistry of the atmosphere · Middle atmosphere

  10. Generation and reactivation of T-cell receptor A joining region pseudogenes in primates

    Energy Technology Data Exchange (ETDEWEB)

    Thiel, C.; Lanchbury, J.S. [Guy`s Hospital, London (United Kingdom); Otting, N. [Biomedical Primate Research Centre, Rijswijk (Netherlands)] [and others

    1996-06-01

    Tandemly duplicated T-cell receptor (Tcr) AJ (J{alpha}) segments contribute significantly to TCRA chain junctional region diversity in mammals. Since only limited data exists on TCRA diversity in nonhuman primates, we examined the TCRAJ regions of 37 chimpanzee and 71 rhesus macaque TCRA cDNA clones derived from inverse polymerase chain reaction on peripheral blood mononuclear cell cDNA of healthy animals. Twenty-five different TCRAJ regions were characterized in the chimpanzee and 36 in the rhesus macaque. Each bears a close structural relationship to an equivalent human TCRAJ region. Conserved amino acid motifs are shared between all three species. There are indications that differences between nonhuman primates and humans exist in the generation of TCRAJ pseudogenes. The nucleotide and amino acid sequences of the various characterized TCRAJ of each species are reported and we compare our results to the available information on human genomic sequences. Although we provide evidence of dynamic processes modifying TCRAJ segments during primate evolution, their repertoire and primary structure appears to be relatively conserved. 21 refs., 2 figs.

  11. The effects of activation procedures on regional cerebral blood flow in humans

    International Nuclear Information System (INIS)

    Rozenfeld, D.; Wolfson, L.I.

    1981-01-01

    Regional cerebral blood flow (r-CBF) can be measured using 133XE and collimated detectors. The radionuclide can be administered either by inhalation or intracarotid injection. Comparison of blood flow determinations at rest and during performance of an activity identifies those brain regions that become active during the performance of the activity. Relatively specific patterns of r-CBF are observed during hand movements, sensory stimulation, eye movements, speech, listening, and reading. Regional CBF changes during reasoning and memorization are less specific and less well characterized. It is clear that brain lesions affect r-CBF responses to various activities, but this effect has not been well correlated with functional deficits or recovery of function. Regional CBF measurement gives information about brain activity and the functional response to experimental manipulation. This approach may well add to our understanding of normal, as well as pathologic, brain functioning

  12. Waste production and regional growth of marine activities an econometric model

    International Nuclear Information System (INIS)

    Bramati, Maria Caterina

    2016-01-01

    Coastal regions are characterized by intense human activity and climatic pressures, often intensified by competing interests in the use of marine waters. To assess the effect of public spending on the regional economy, an econometric model is here proposed. Not only are the regional investment and the climatic risks included in the model, but also variables related to the anthropogenic pressure, such as population, economic activities and waste production. Feedback effects of economic and demographic expansion on the pollution of coastal areas are also considered. It is found that dangerous waste increases with growing shipping and transportation activities and with growing population density in non-touristic coastal areas. On the other hand, the amount of non-dangerous wastes increases with marine mining, defense and offshore energy production activities. However, lower waste production occurs in areas where aquaculture and touristic industry are more exploited, and accompanied by increasing regional investment in waste disposal. - Highlights: • We use an econometric model as a tool for assessing the effects of regional policies on the development of economic activities related to the use of the sea and on the impact on the marine environment. • Through scenario simulation we provide strategic guidelines for policy makers and economic planners • The model features feedback effects of economic and demographic expansion on the pollution of coastal areas.

  13. A regional analysis of Tourism Specialization in Spain

    OpenAIRE

    Perez-Dacal, Diana; Pena-Boquete, Yolanda

    2013-01-01

    Tourism sector is playing an important role in the development of a region, contributing to the economy growth and job creation. Despite of the actual crisis, Tourism activities continues to growth in the last year (UNWTO 2011). Also, Spain maintains in the better positions of the world ranking. Furthermore, Tourism activities generate around 10% of GPD and represents 11.5% of total workers of the Spanish Economy. Nevertheless, this is not true for all the Spanish Regions. There are regional ...

  14. Basal levels of metabolic activity are elevated in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): measurement of regional activity of cytochrome oxidase and lactate dehydrogenase by histochemistry.

    Science.gov (United States)

    Dufour, Franck; Koning, Estelle; Nehlig, Astrid

    2003-08-01

    The Genetic Absence Epilepsy Rats from Strasbourg (GAERS) are considered an isomorphic, predictive, and homologous model of human generalized absence epilepsy. It is characterized by the expression of spike-and-wave discharges in the thalamus and cortex. In this strain, basal regional rates of cerebral glucose utilization measured by the quantitative autoradiographic [(14)C]2-deoxyglucose technique display a widespread consistent increase compared to a selected strain of genetically nonepileptic rats (NE). In order to verify whether these high rates of glucose metabolism are paralleled by elevated activities of the enzymes of the glycolytic and tricarboxylic acid cycle pathways, we measured by histochemistry the regional activity of the two key enzymes of glucose metabolism, lactate dehydrogenase (LDH) for the anaerobic pathway and cytochrome oxidase (CO) for the aerobic pathway coupled to oxidative phosphorylation. CO and LDH activities were significantly higher in GAERS than in NE rats in 24 and 28 of the 30 brain regions studied, respectively. The differences in CO and LDH activity between both strains were widespread, affected all brain systems studied, and ranged from 12 to 63%. The data of the present study confirm the generalized increase in cerebral glucose metabolism in GAERS, occurring both at the glycolytic and at the oxidative step. However, they still do not allow us to understand why the ubiquitous mutation(s) generates spike-and-wave discharges only in the thalamocortical circuit.

  15. Prefrontal cortex modulates desire and dread generated by nucleus accumbens glutamate disruption.

    Science.gov (United States)

    Richard, Jocelyn M; Berridge, Kent C

    2013-02-15

    Corticolimbic circuits, including direct projections from prefrontal cortex to nucleus accumbens (NAc), permit top-down control of intense motivations generated by subcortical circuits. In rats, localized disruptions of glutamate signaling within medial shell of NAc generate desire or dread, anatomically organized along a rostrocaudal gradient analogous to a limbic keyboard. At rostral locations in shell, these disruptions generate appetitive eating, but at caudal locations the disruptions generate progressively fearful behaviors (distress vocalizations, escape attempts, and antipredator reactions). Here, we asked whether medial prefrontal cortex can modulate intense motivations generated by subcortical NAc disruptions. We used simultaneous microinjections in medial prefrontal cortex regions and in NAc shell to examine whether the desire or dread generated by NAc shell disruptions is modulated by activation/inhibition of three specific regions of prefrontal cortex: medial orbitofrontal cortex, infralimbic cortex (homologous to area 25 or subgenual anterior cingulate in the human), or prelimbic cortex (midventral anterior cingulate). We found that activation of medial orbitofrontal cortex biased intense bivalent motivation in an appetitive direction by amplifying generation of eating behavior by middle to caudal NAc disruptions, without altering fear. In contrast, activation of infralimbic prefrontal cortex powerfully and generally suppressed both appetitive eating and fearful behaviors generated by NAc shell disruptions. These results suggest that corticolimbic projections from discrete prefrontal regions can either bias motivational valence or generally suppress subcortically generated intense motivations of desire or fear. Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  16. Relation of flare activity to the approach and separation of sunspots in an active region and to its magnetic properties

    International Nuclear Information System (INIS)

    Markova, E.

    1978-01-01

    The relation between the flare activity of active regions within the scope of a large complex and the magnetic gradients of these active regions and their daily variations is investigated in the interval of the exceptionally high flare activity occurring in June 1970. New indices, characterizing the active region, were defined, e.g., the instantaneous sunspot-area density and the instantaneous sunspot-number density. These indices were determined on the basis of measurements of the surface containing all sunspots of the complex of active regions enclosed by an envelope. An attempt was made to substitute the surface in the relation for the individual indices by distance. The daily variations of these indices were again compared with the flare activity and some mutual relations were derived. (author)

  17. The Location of ICT activities in EU regions. Implications for regional policies

    Directory of Open Access Journals (Sweden)

    Salvador Barrios

    2008-11-01

    Full Text Available The location of ICT producing industries does matter for global competitivenessand long-run growth potential. For instance, the differing contribution ofICT to economic growth between the US and the EU is often mentioned as one of themain cause explaining the diverging growth performance of these two areas since themid-1990s. In turn, since the mid-1990s, countries with especially dynamic economicgrowth have tended to be highly specialized in ICT-producing and ICT-using industries,see van Ark and Inkaar (2005. More generally, ICT producing sectors, tendto promote technological change and innovative capability which are seen to be at thecore of economic growth and competitiveness. When considering the EU economy,ICT industries appear to be concentrated in a limited number of regions, see Koski etal. (2002 for empirical evidence. Afirst objective of the present paper is to documentthe location of ICT producing industries in European regions in order to map existingEU clusters as well as to analyze recent changes in these industries using recent dataon employment and firm location, especially in relation to the EU enlargement thathas taken place in May 2004. The location of the ICT-producing sectors is not the endof the story however. A crucial aspect concerns the nature of activities that are beingundertaken in different regions. Importantly, ICT industries do have different characteristicsin terms of human capital, skill requirement, and knowledge content. In particular,because of the positive association between human capital, knowledge andlong-run growth, it is important to analyze to what extent EU regional ICT clustersdiffer in according to these characteristics. The second question addressed in the paperconcerns the nature of ICT activities undertaken in EU regions. Finally, the paperprovides econometric estimates of the location of firms in ICT industries across EUregions. The paper considers more specifically the case of multinationals

  18. Organizational-economic maintenance of innovation activity in the region: comparative assessment

    Directory of Open Access Journals (Sweden)

    Nadezhda Igorevna Antipina

    2014-05-01

    Full Text Available The article proposes the approach to evaluate the organizational-economic maintenance of innovation activity in the regions in quantitative and qualitative indicators, as well as the method to calculate the assessment of regulatory support of this activity. It justifies the author’s approach of comparative efficiency evaluation of innovation legislation and regions’ innovation development level. The article gives the qualitative estimation of regulatory support of innovation development in the regions that are innovation leaders. It singles out key directions to develop regulatory support of innovation activity, which encourage RF subjects’ innovation activity

  19. Air pollution and health implications of regional electricity transfer at generational centre and design of compensation mechanism

    Science.gov (United States)

    Relhan, Nemika

    India's electricity generation is primarily from coal. As a result of interconnection of grid and establishment of pithead power plants, there has been increased electricity transfer from one region to the other. This results in imbalance of pollution loads between the communities located in generation vis-a-vis consumption region. There may be some states, which are major power generation centres and hence are facing excessive environmental degradation. On the other hand, electricity importing regions are reaping the benefits without paying proper charges for it because present tariff structure does not include the full externalities in it. The present study investigates the distributional implications in terms of air pollution loads between the electricity generation and consumption regions at the state level. It identifies the major electricity importing and exporting states in India. Next, as a case study, it estimates the health damage as a result of air pollution from thermal power plants (TPPs) located in a critically polluted region that is one of the major generator and exporter of electricity. The methodology used to estimate the health damage is based on impact pathway approach. In this method, air pollution modelling has been performed in order to estimate the gridded Particulate Matter (PM) concentration at various receptor locations in the study domain. The air quality modeling exercise helps to quantify the air pollution concentration in each grid and also apportion the contribution of power plants to the total concentration. The health impacts as a result of PM have been estimated in terms of number of mortality and morbidity cases using Concentration Response Function (CRF's) available in the literature. Mortality has been converted into Years of Life Lost (YOLL) using life expectancy table and age wise death distribution. Morbidity has been estimated in terms of number of cases with respect to various health end points. To convert this health

  20. Research and development activities of a neutron generator facility

    International Nuclear Information System (INIS)

    Darsono Sudjatmoko; Pramudita Anggraita; Sukarman Aminjoyo

    2000-01-01

    The neutron generator facility at YNRC is used for elemental analysis, nuclear data measurement and education. In nuclear data measurement the focus is on re-evaluating the existing scattered nuclear activation cross-section to obtain systematic data for nuclear reactions such as (n,p), (n,α), and (n,2n). In elemental analysis it is used for analyzing the Nitrogen (N), Phosphor (P) and Potassium (K) contents in chemical and natural fertilizers (compost), protein in rice, soybean, and corn and pollution level in rivers. The neutron generator is also used for education and training of BATAN staff and university students. The facility can also produce neutron generator components. (author)

  1. Knowledge Creation and Regional Spillovers: Empirical Evidence from Germany

    Directory of Open Access Journals (Sweden)

    Akhvlediani Tinatin

    2017-12-01

    Full Text Available The paper examines the effects of intra- and inter-regional knowledge spillovers on innovative activities in German states using the augmented Griliches-Jaffe knowledge production function. The “Harris market potential” type index is calculated to proxy for inter-regional knowledge transfers of two types: industrial knowledge transfers generated from the business enterprise sector and academic spillovers generated from universities across all German states. The model also includes the concentration of high-tech enterprises, in order to capture the agglomeration effect in the local economy. The estimation results reveal that not only do local private and university research efforts have a positive and significant effect on local innovative activities, but there are also important interregional knowledge spillovers across the German regions.

  2. Approach to analysis of inter-regional similarity of investment activity support measures in legislation of regions (on the example of Krasnoyarsk region

    Directory of Open Access Journals (Sweden)

    Valentina F. Lapo

    2017-01-01

    Full Text Available The most part of stimulation methods in Russia are concentrated in legal documents of the regions of the Russian Federation. They directed on intensification of investment activity in regions. How similar are these investment stimulation conceptions? There is no mention in the literature of the methodical questions of quantitative analysis and inter-regional comparisons. In addition, there are no results of statistical research of inter-regional correlations of stimulation methods and analysis of dynamics of this process. There are no special measuring instruments. The presented work is aimed at completion of these blanks. The approach for the spatial correlation analysis of legislative norms is offered in research. Classification of investments’ stimulation methods is developed. The way of preparing and coding data for research is offered. The approach and system of coefficients for the analysis of inter-regional interrelations of legislative systems of investments’ stimulation is offered. A proximity coefficient of regional legislation, a factor of structure similarity and a dynamic coincidence index are proposed. The space-time base of investment stimulation methods on Russian Federation regions for 12 years is collected and statistically processed for research. There are only 758 documents. A source of texts is a site of the Ministry of Justice of the Russian Federation.Research of documents has allowed revealing a number of laws in formation of regional investment stimulation systems. The regions that are the most similar in terms of structure of stimulation methods are identified. We have found the group of regions for which it is observed the increase in similarity of the legislation and the group with the reduction of similarity. Therefore, it is obvious that the general trend to reduction of similarity in the legislation takes place between Krasnoyarsk territory and the other regions of the Russian Federation. Calculations have

  3. Thermal requirements and estimated number of generations of Neopamera bilobata (Say in strawberry-producing regions of Brazil

    Directory of Open Access Journals (Sweden)

    Taciana Melissa de Azevedo Kuhn

    2017-12-01

    Full Text Available ABSTRACT: The thermal threshold and thermal requirements of Neopamera bilobata were determined, and the number of generations that this species may produce in the main strawberry-producing regions of Brazil was estimated. In a climate chamber (70±10% RH and 12h photophase at 16, 19, 22, 25, 28, or 30±1°C, the development of 120 eggs was monitored until the adult stage, at each temperature. Nymphs were maintained in individual cages and fed on strawberry fruits of the cultivar Aromas. The mean duration and viability of the egg and nymph stages were calculated by estimating the lower and upper developmental thresholds and the thermal constant, and this information was used to estimate the number of generations per year in different strawberry-producing regions of Brazil. The egg-to-adult duration decreased as temperatures increased, up to 28°C (93.4, 83.2, 43.9, and 31.4 days at 19, 22, 25, and 28°C, respectively. Viability of nymphs was highest between 22 and 28°C. At 30°C, the egg-to-adult duration increased (36 days, while the viability decreased (11.11%. The lower egg-to-adult developmental threshold was 15.2°C and the thermal constant was 418.4 degree-days. Calculating the number of generations indicated that the largest number (5.1 generations yr-1 was obtained for the municipality of Jaboti, Paraná, and the smallest for Caxias do Sul, Rio Grande do Sul (1.9 generations yr-1. Our findings demonstrated that important strawberry-producing regions in Brazil are suitable for the development of N. bilobata.

  4. Self-generation of dissipative solitons in magnonic quasicrystal active ring resonator

    International Nuclear Information System (INIS)

    Grishin, S. V.; Beginin, E. N.; Morozova, M. A.; Sharaevskii, Yu. P.; Nikitov, S. A.

    2014-01-01

    Self-generation of dissipative solitons in the magnonic quasicrystal (MQC) active ring resonator is studied theoretically and experimentally. The developed magnonic crystal has quasiperiodic Fibonacci type structure. Frequency selectivity of the MQC together with the parametric three-wave decay of magnetostatic surface spin wave (MSSW) leads to the dissipative soliton self-generation. The transfer matrix method is used to describe MQC transmission responses. Besides, the model of MQC active ring resonator is suggested. The model includes three coupled differential equations describing the parametric decay of MSSW and two differential equations of linear oscillators describing the frequency selectivity of MQC. Numerical simulation results of dissipative soliton self-generation are in a fair agreement with experimental data

  5. Self-generation of dissipative solitons in magnonic quasicrystal active ring resonator

    Energy Technology Data Exchange (ETDEWEB)

    Grishin, S. V., E-mail: grishfam@sgu.ru; Beginin, E. N.; Morozova, M. A.; Sharaevskii, Yu. P. [Laboratory “Metamaterials,” Saratov State University, Saratov 410012 (Russian Federation); Nikitov, S. A. [Laboratory “Metamaterials,” Saratov State University, Saratov 410012 (Russian Federation); Kotel' nikov Institute of Radioengineering and Electronics, Russian Academy of Science, Moscow 125009 (Russian Federation)

    2014-02-07

    Self-generation of dissipative solitons in the magnonic quasicrystal (MQC) active ring resonator is studied theoretically and experimentally. The developed magnonic crystal has quasiperiodic Fibonacci type structure. Frequency selectivity of the MQC together with the parametric three-wave decay of magnetostatic surface spin wave (MSSW) leads to the dissipative soliton self-generation. The transfer matrix method is used to describe MQC transmission responses. Besides, the model of MQC active ring resonator is suggested. The model includes three coupled differential equations describing the parametric decay of MSSW and two differential equations of linear oscillators describing the frequency selectivity of MQC. Numerical simulation results of dissipative soliton self-generation are in a fair agreement with experimental data.

  6. Comprehensive Assessment of Integration Activity of Business Structures in Russian Regions

    Directory of Open Access Journals (Sweden)

    Mariya Gennad’evna Karelina

    2016-11-01

    Full Text Available In the context of economic sanctions and growing international isolation, the research into regional differences in integration development acquires special relevance for Russia; this fact determines the need for a comprehensive assessment of integration activity of business structures in Russian regions. The diversity of approaches to the study of problems and prospects of economic integration and the current debate about the role of integration processes in the development of regional economies determined a comprehensive approach to the concepts of “integration” and “integration activity” in order to create objective prerequisites for analyzing integration activity of business structures in the regions of Russia. The information base of the research is the data of Russian information and analytical agencies. The tools used in the research include methods for analyzing structural changes, methods for analyzing economic differentiation and concentration, nonparametric statistics methods, and econometric analysis methods. The first part of the paper shows that socio-economic development in constituent entities of Russia is closely connected with the operation of integrated business structures located on their territory. Having studied the structure and dynamics of integration activity, we reveal the growing heterogeneity of integration activity of business structures in Russian regions. The hypothesis about significant divergence of mergers and acquisitions for corporate structures in Russian regions was confirmed by high values of the Gini coefficient, the Herfindahl index and the decile differentiation coefficient. The second part of the paper contains a comparative analysis and proposes an econometric approach to the measurement of integration activity of business structures in subjects of the Russian Federation on the basis of integral synthetic categories. The approach we propose focuses on the development of a system of indicators

  7. Drivers of Concentration of Economic Activity in Russia’s Regions

    Directory of Open Access Journals (Sweden)

    Svetlana Nikolaevna Rastvortseva

    2016-05-01

    Full Text Available The uneven distribution of economic activity in Russia promotes the differentiation of its constituent entities by level of development. Regions are independent participants of economic relations, and they often act as competitors rather than partners. Agglomeration effects arise in more successful regions and contribute to the concentration of resources, manufacturing enterprises, service providers, skilled workers, and scientific and technological knowledge. The aim of the study, the results of which are reflected in the paper, is to identify the factors and assess their impact on the concentration (dispersion of economic activity on the basis of Russia’s regions. The paper describes the benefits of agglomeration processes from the standpoint of economic geography, allocation theory and international trade theory. The concentration of economic activity in Russia’s regions is estimated by the Herfindahl–Hirschman index of industrial production taking into consideration the volume of investments in fixed capital and the number of people employed in the economy in Russia’s regions in 1990–2013. It is determined that fixed capital investments have the propensity to concentrate, but react strongly to economic crises. Labor resources, by contrast, are distributed relatively evenly, and their concentration in certain regions is increasing steadily. The article considers key factors such as wage growth, distance to large cities, direct foreign investment, road network density, the degree of development of the services sector in the region. The factor model is constructed using the least squares method. The authors conclude that the growth of wages in the region (relative to national average has a negative effect on the concentration of economic activity. There is a positive correlation between the growth of direct foreign investment and the density of hard surface roads. The development of services has the greatest positive impact on

  8. Regional passive seismic monitoring reveals dynamic glacier activity on Spitsbergen, Svalbard

    Directory of Open Access Journals (Sweden)

    Andreas Köhler

    2015-12-01

    Full Text Available Dynamic glacier activity is increasingly observed through passive seismic monitoring. We analysed near-regional-scale seismicity on the Arctic archipelago of Svalbard to identify seismic icequake signals and to study their spatial–temporal distribution within the 14-year period from 2000 until 2013. This is the first study that uses seismic data recorded on permanent broadband stations to detect and locate icequakes in different regions of Spitsbergen, the main island of the archipelago. A temporary local seismic network and direct observations of glacier calving and surging were used to identify icequake sources. We observed a high number of icequakes with clear spectral peaks between 1 and 8 Hz in different parts of Spitsbergen. Spatial clusters of icequakes could be associated with individual grounded tidewater glaciers and exhibited clear seasonal variability each year with more signals observed during the melt season. Locations at the termini of glaciers, and correlation with visual calving observations in situ at Kronebreen, a glacier in the Kongsfjorden region, show that these icequakes were caused dominantly by calving. Indirect evidence for glacier surging through increased calving seismicity was found in 2003 at Tunabreen, a glacier in central Spitsbergen. Another type of icequake was observed in the area of the Nathorstbreen glacier system. Seismic events occurred upstream of the glacier within a short time period between January and May 2009 during the initial phase of a major glacier surge. This study is the first step towards the generation and implementation of an operational seismic monitoring strategy for glacier dynamics in Svalbard.

  9. The Phosphatase Inhibitor Calyculin-A Impairs Clot Retraction, Platelet Activation, and Thrombin Generation

    Directory of Open Access Journals (Sweden)

    Renáta Hudák

    2017-01-01

    Full Text Available The aim of this study was to investigate the effect of the serine/threonine protein phosphatase inhibitor, calyculin-A (CLA, on clot formation and on the procoagulant activity of human platelets. Platelet-rich plasma (PRP samples were preincubated with buffer or CLA and subsequently platelets were activated by the protease-activated receptor 1 (PAR-1 activator, thrombin receptor activating peptide (TRAP. Clot retraction was detected by observing clot morphology up to 1 hour, phosphatidylserine- (PS- expression was studied by flow cytometry, and thrombin generation was measured by a fluorimetric assay. For the intracellular Ca2+ assay, platelets were loaded with calcium-indicator dyes and the measurements were carried out using a ratiometric method with real-time confocal microscopy. CLA preincubation inhibited clot retraction, PS-expression, and thrombin formation. TRAP activation elicited Ca2+ response and PS-expression in a subset of platelets. The activated PRP displayed significantly faster and enhanced thrombin generation compared to nonactivated samples. CLA pretreatment abrogated PS-exposure and clot retraction also in TRAP-activated samples. As a consequence of the inhibitory effect on calcium elevation and PS-expression, CLA significantly downregulated thrombin generation in PRP. Our results show that CLA pretreatment may be a useful tool to investigate platelet activation mechanisms that contribute to clot formation and thrombin generation.

  10. Carnosine: effect on aging-induced increase in brain regional monoamine oxidase-A activity.

    Science.gov (United States)

    Banerjee, Soumyabrata; Poddar, Mrinal K

    2015-03-01

    Aging is a natural biological process associated with several neurological disorders along with the biochemical changes in brain. Aim of the present investigation is to study the effect of carnosine (0.5-2.5μg/kg/day, i.t. for 21 consecutive days) on aging-induced changes in brain regional (cerebral cortex, hippocampus, hypothalamus and pons-medulla) mitochondrial monoamine oxidase-A (MAO-A) activity with its kinetic parameters. The results of the present study are: (1) The brain regional mitochondrial MAO-A activity and their kinetic parameters (except in Km of pons-medulla) were significantly increased with the increase of age (4-24 months), (2) Aging-induced increase of brain regional MAO-A activity including its Vmax were attenuated with higher dosages of carnosine (1.0-2.5μg/kg/day) and restored toward the activity that observed in young, though its lower dosage (0.5μg/kg/day) were ineffective in these brain regional MAO-A activity, (3) Carnosine at higher dosage in young rats, unlike aged rats significantly inhibited all the brain regional MAO-A activity by reducing their only Vmax excepting cerebral cortex, where Km was also significantly enhanced. These results suggest that carnosine attenuated the aging-induced increase of brain regional MAO-A activity by attenuating its kinetic parameters and restored toward the results of MAO-A activity that observed in corresponding brain regions of young rats. Copyright © 2014 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  11. Photospheric Velocity Structures during the Emergence of Small Active Regions on the Sun

    International Nuclear Information System (INIS)

    Khlystova, Anna; Toriumi, Shin

    2017-01-01

    We study the plasma flows in the solar photosphere during the emergence of two small active regions, NOAA 9021 and 10768. Using Solar and Heliospheric Observatory /Michelson Doppler Imager data, we find that the strong plasma upflows appear at the initial stage of active region formation, with maximum upflow velocities of −1650 and −1320 m s −1 . The structures with enhanced upflows have size ∼8 Mm in diameter, and they exist for 1–2 hr. The parameters of the enhanced upflows are consistent with those of the large active region NOAA 10488, which may suggest the possibility that the elementary emerging magnetic loops that appear at the earliest phase of active region formation have similar properties, irrespective of scales of active regions. Comparison between the observations and a numerical simulation of magnetic flux emergence shows a striking consistency. We find that the driving force of the plasma upflow is at first the gas pressure gradient and later the magnetic pressure gradient.

  12. Photospheric Velocity Structures during the Emergence of Small Active Regions on the Sun

    Energy Technology Data Exchange (ETDEWEB)

    Khlystova, Anna [Institute of Solar-Terrestrial Physics SB RAS, Lermontov St., 126a, 664033 Irkutsk (Russian Federation); Toriumi, Shin, E-mail: hlystova@iszf.irk.ru, E-mail: shin.toriumi@nao.ac.jp [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

    2017-04-10

    We study the plasma flows in the solar photosphere during the emergence of two small active regions, NOAA 9021 and 10768. Using Solar and Heliospheric Observatory /Michelson Doppler Imager data, we find that the strong plasma upflows appear at the initial stage of active region formation, with maximum upflow velocities of −1650 and −1320 m s{sup −1}. The structures with enhanced upflows have size ∼8 Mm in diameter, and they exist for 1–2 hr. The parameters of the enhanced upflows are consistent with those of the large active region NOAA 10488, which may suggest the possibility that the elementary emerging magnetic loops that appear at the earliest phase of active region formation have similar properties, irrespective of scales of active regions. Comparison between the observations and a numerical simulation of magnetic flux emergence shows a striking consistency. We find that the driving force of the plasma upflow is at first the gas pressure gradient and later the magnetic pressure gradient.

  13. ON MAGNETIC ACTIVITY BAND OVERLAP, INTERACTION, AND THE FORMATION OF COMPLEX SOLAR ACTIVE REGIONS

    Energy Technology Data Exchange (ETDEWEB)

    McIntosh, Scott W. [High Altitude Observatory, National Center for Atmospheric Research, P.O. Box 3000, Boulder, CO 80307 (United States); Leamon, Robert J., E-mail: mscott@hao.ucar.edu [Department of Physics, Montana State University, Bozeman, MT 59717 (United States)

    2014-11-20

    Recent work has revealed a phenomenological picture of the how the ∼11 yr sunspot cycle of the Sun arises. The production and destruction of sunspots is a consequence of the latitudinal-temporal overlap and interaction of the toroidal magnetic flux systems that belong to the 22 yr magnetic activity cycle and are rooted deep in the Sun's convective interior. We present a conceptually simple extension of this work, presenting a hypothesis on how complex active regions can form as a direct consequence of the intra- and extra-hemispheric interaction taking place in the solar interior. Furthermore, during specific portions of the sunspot cycle, we anticipate that those complex active regions may be particularly susceptible to profoundly catastrophic breakdown, producing flares and coronal mass ejections of the most severe magnitude.

  14. A bibliometric analysis of the development of next generation active nanotechnologies

    International Nuclear Information System (INIS)

    Suominen, Arho; Li, Yin; Youtie, Jan; Shapira, Philip

    2016-01-01

    Delineating the emergence of nanotechnologies that offer new functionalities is an important element in an anticipatory approach to the governance of nanotechnology and its potential impacts. This paper examines the transition to next generation active nanotechnologies which incorporate functions that respond to the environment or systems concepts that combine devices and structures that are dynamic and which may change their states in use. We develop an approach to identifying these active nanotechnologies and then use bibliometric analysis to examine the extent of research papers and patents involving these concepts. We also examine references to environmental, health, and safety concepts in these papers, given that these next generation nanotechnologies are likely to have risk profiles that are different from those of first-generation passive nanomaterials. Our results show a steady growth overall in focus on active nanotechnologies in the research literature and in patents over the study period of 1990–2010. We also find an increase in consideration given to environmental, health, and safety topics. While gaps are highlighted in our understanding of research and innovation in active nanotechnologies, the results suggest that there is beginning to be a shift to active nanotechnologies, with the implication that governance processes need to be conscious of this shift and to prepare for it.

  15. A bibliometric analysis of the development of next generation active nanotechnologies

    Energy Technology Data Exchange (ETDEWEB)

    Suominen, Arho [VTT Technical Research Centre of Finland (Finland); Li, Yin; Youtie, Jan, E-mail: jan.youtie@innovate.gatech.edu; Shapira, Philip [Georgia Institute of Technology (United States)

    2016-09-15

    Delineating the emergence of nanotechnologies that offer new functionalities is an important element in an anticipatory approach to the governance of nanotechnology and its potential impacts. This paper examines the transition to next generation active nanotechnologies which incorporate functions that respond to the environment or systems concepts that combine devices and structures that are dynamic and which may change their states in use. We develop an approach to identifying these active nanotechnologies and then use bibliometric analysis to examine the extent of research papers and patents involving these concepts. We also examine references to environmental, health, and safety concepts in these papers, given that these next generation nanotechnologies are likely to have risk profiles that are different from those of first-generation passive nanomaterials. Our results show a steady growth overall in focus on active nanotechnologies in the research literature and in patents over the study period of 1990–2010. We also find an increase in consideration given to environmental, health, and safety topics. While gaps are highlighted in our understanding of research and innovation in active nanotechnologies, the results suggest that there is beginning to be a shift to active nanotechnologies, with the implication that governance processes need to be conscious of this shift and to prepare for it.

  16. LOCAL DEVELOPMENT IN NORTHEST REGION THROUGH ACTIVITIES IN ITC DOMAIN

    Directory of Open Access Journals (Sweden)

    Daniela\tENACHESCU

    2015-06-01

    Full Text Available Economic areas with high technology are key drivers in sustainable regional development, including unemployment and consequently decreasing population migration in the region. Northeast Region is the largest development region of Romania in terms of number of inhabitants and the owned area. On 01/01/2014, according to balance employment, labor resources of the region were numbered 2,428,700, which represent 49.6% of employed population. The registered unemployment rate at 31 August 2014 was 6.5%, with 82 thousand unemployed registered. In terms of participation in the main economic activities, civilian employment in agriculture, forestry and fishing is predominant (40.1% while in service, civilian employment is 37.1%, while industry and construction is 22.8%. The paper aims to analyze the situation that the potential employment and development opportunities for the Northeast region through activities in the field of ITC domain. Unfortunately, this area was the worst in most indicators, the use of computers and the internet to the turnover of companies and investments in the IT & C and unfortunately in terms of employment population that is under 50%

  17. Derivation of a regional active-optical reflectance sensor corn algorithm

    Science.gov (United States)

    Active-optical reflectance sensor (AORS) algorithms developed for in-season corn (Zea mays L.) N management have traditionally been derived using sub-regional scale information. However, studies have shown these previously developed AORS algorithms are not consistently accurate when used on a region...

  18. FINE MAGNETIC FEATURES AND CHIRALITY IN SOLAR ACTIVE REGION NOAA 10930

    International Nuclear Information System (INIS)

    Zhang Hongqi

    2010-01-01

    In this paper, we present fine magnetic features near the magnetic inversion line in the solar active region NOAA 10930. The high-resolution vector magnetograms obtained by Hinode allow detailed analyses around magnetic fibrils in the active region. The analyses are based on the fact that the electric current density can be divided into two components: the shear component caused by the magnetic inhomogeneity and the twist component caused by the magnetic field twist. The relationships between magnetic field, electric current density, and its two components are examined. It is found that the individual magnetic fibrils are dominated by the current density component caused by the magnetic inhomogeneity, while the large-scale magnetic region is generally dominated by the electric current component associated with the magnetic twist. The microstructure of the magnetic field in the solar atmosphere is far from the force-free field. The current mainly flows around the magnetic flux fibrils in the active regions.

  19. Magnetic Structure of Sites of Braiding in Hi-C Active Region

    Science.gov (United States)

    Tiwari, S. K.; Alexander, C. E.; Winebarger, A.; Moore, R. L.

    2014-01-01

    High-resolution Coronal Imager (Hi-C) observations of an active region (AR) corona, at a spatial resolution of 0.2 arcsec, have offered the first direct evidence of field lines braiding, which could deliver sufficient energy to heat the AR corona by current dissipation via magnetic reconnection, a proposal given by Parker three decades ago. The energy required to heat the corona must be transported from the photosphere along the field lines. The mechanism that drives the energy transport to the corona is not yet fully understood. To investigate simultaneous magnetic and intensity structure in and around the AR in detail, we use SDO/HMI+AIA data of + / - 2 hours around the 5 minute Hi-C flight. In the case of the QS, work done by convection/granulation on the inter-granular feet of the coronal field lines probably translates into the heat observed in the corona. In the case of the AR, as here, there could be flux emergence, cancellation/submergence, or shear flows generating large stress and tension in coronal field loops which is released as heat in the corona. However, to the best of our knowledge, there is no observational evidence available to these processes. We investigate the changes taking place in the photospheric feet of the magnetic field involved with brightenings in the Hi-C AR corona. Using HMI 45s magnetograms of four hours we find that, out of the two Hi-C sub-regions where the braiding of field lines were recently detected, flux emergence takes place in one region and flux cancellation in the other. The field in these sub-regions are highly sheared and have apparent high speed plasma flows at their feet. Therefore, shearing flows plausibly power much of the coronal and transition region heating in these areas of the AR. In addition, the presence of large flux emergence/cancellation strongly suggests that the work done by these processes on the pre-existing field also drives much of the observed heating.

  20. A 3-Step Algorithm Using Region-Based Active Contours for Video Objects Detection

    Directory of Open Access Journals (Sweden)

    Stéphanie Jehan-Besson

    2002-06-01

    Full Text Available We propose a 3-step algorithm for the automatic detection of moving objects in video sequences using region-based active contours. First, we introduce a very full general framework for region-based active contours with a new Eulerian method to compute the evolution equation of the active contour from a criterion including both region-based and boundary-based terms. This framework can be easily adapted to various applications, thanks to the introduction of functions named descriptors of the different regions. With this new Eulerian method based on shape optimization principles, we can easily take into account the case of descriptors depending upon features globally attached to the regions. Second, we propose a 3-step algorithm for detection of moving objects, with a static or a mobile camera, using region-based active contours. The basic idea is to hierarchically associate temporal and spatial information. The active contour evolves with successively three sets of descriptors: a temporal one, and then two spatial ones. The third spatial descriptor takes advantage of the segmentation of the image in intensity homogeneous regions. User interaction is reduced to the choice of a few parameters at the beginning of the process. Some experimental results are supplied.

  1. Fast and robust generation of feature maps for region-based visual attention.

    Science.gov (United States)

    Aziz, Muhammad Zaheer; Mertsching, Bärbel

    2008-05-01

    Visual attention is one of the important phenomena in biological vision which can be followed to achieve more efficiency, intelligence, and robustness in artificial vision systems. This paper investigates a region-based approach that performs pixel clustering prior to the processes of attention in contrast to late clustering as done by contemporary methods. The foundation steps of feature map construction for the region-based attention model are proposed here. The color contrast map is generated based upon the extended findings from the color theory, the symmetry map is constructed using a novel scanning-based method, and a new algorithm is proposed to compute a size contrast map as a formal feature channel. Eccentricity and orientation are computed using the moments of obtained regions and then saliency is evaluated using the rarity criteria. The efficient design of the proposed algorithms allows incorporating five feature channels while maintaining a processing rate of multiple frames per second. Another salient advantage over the existing techniques is the reusability of the salient regions in the high-level machine vision procedures due to preservation of their shapes and precise locations. The results indicate that the proposed model has the potential to efficiently integrate the phenomenon of attention into the main stream of machine vision and systems with restricted computing resources such as mobile robots can benefit from its advantages.

  2. Factors Influencing Compensation Demanded for Environmental Impacts Generated by Different Economic Activities

    Directory of Open Access Journals (Sweden)

    Virna Vaneza Gutiérrez

    2015-07-01

    Full Text Available This work advances the understanding of compensation demanded for environmental impacts on atmosphere, lakes and rivers, soil, and ocean generated by mining, urban, fishing and agriculture activities. Our aims are to determine whether compensation demanded depends on the standard variables used in the field of risk perception (as perceived risk, public acceptability and trust in regulating authorities, and to explore whether these relationships depend on the environment affected and on the economic activity generating the impacts. General Linear Models were used to analyze survey responses from 427 citizens of Santiago, Chile. Results showed that compensation demanded depends on perceived risk, acceptability, and on the economic activity, but not on the environment affected. Acceptability depends on trust in authorities, on perceived risk and on the economic activity. Perceived risk depends on trust, the economic activity and the environment affected. Overall, environmental impacts from the mining industry are perceived as riskier, less acceptable, and have a higher compensation demanded than those generated by the other sectors. These results suggest that to achieve sustainable development, regulations should consider not only environmental impacts but also the economic activity originating them.

  3. The Neural Circuits that Generate Tics in Gilles de la Tourette Syndrome

    Science.gov (United States)

    Wang, Zhishun; Maia, Tiago V.; Marsh, Rachel; Colibazzi, Tiziano; Gerber, Andrew; Peterson, Bradley S.

    2014-01-01

    Objective To study neural activity and connectivity within cortico-striato-thalamo-cortical circuits and to reveal circuit-based neural mechanisms that govern tic generation in Tourette syndrome. Method We acquired fMRI data from 13 participants with Tourette syndrome and 21 controls during spontaneous or simulated tics. We used independent component analysis with hierarchical partner matching to isolate neural activity within functionally distinct regions of cortico-striato-thalamo-cortical circuits. We used Granger causality to investigate causal interactions among these regions. Results We found that the Tourette group exhibited stronger neural activity and interregional causality than controls throughout all portions of the motor pathway including sensorimotor cortex, putamen, pallidum, and substania nigra. Activity in these areas correlated positively with the severity of tic symptoms. Activity within the Tourette group was stronger during spontaneous tics than during voluntary tics in somatosensory and posterior parietal cortices, putamen, and amygdala/hippocampus complex, suggesting that activity in these regions may represent features of the premonitory urges that generate spontaneous tic behaviors. In contrast, activity was weaker in the Tourette group than in controls within portions of cortico-striato-thalamo-cortical circuits that exert top-down control over motor pathways (caudate and anterior cingulate cortex), and progressively less activity in these regions accompanied more severe tic symptoms, suggesting that faulty activity in these circuits may fail to control tic behaviors or the premonitory urges that generate them. Conclusions Our findings taken together suggest that tics are caused by the combined effects of excessive activity in motor pathways and reduced activation in control portions of cortico-striato-thalamo-cortical circuits. PMID:21955933

  4. The Effect of "Rogue" Active Regions on the Solar Cycle

    Science.gov (United States)

    Nagy, Melinda; Lemerle, Alexandre; Labonville, François; Petrovay, Kristóf; Charbonneau, Paul

    2017-11-01

    The origin of cycle-to-cycle variations in solar activity is currently the focus of much interest. It has recently been pointed out that large individual active regions with atypical properties can have a significant impact on the long-term behavior of solar activity. We investigate this possibility in more detail using a recently developed 2×2D dynamo model of the solar magnetic cycle. We find that even a single "rogue" bipolar magnetic region (BMR) in the simulations can have a major effect on the further development of solar activity cycles, boosting or suppressing the amplitude of subsequent cycles. In extreme cases, an individual BMR can completely halt the dynamo, triggering a grand minimum. Rogue BMRs also have the potential to induce significant hemispheric asymmetries in the solar cycle. To study the effect of rogue BMRs in a more systematic manner, a series of dynamo simulations were conducted, in which a large test BMR was manually introduced in the model at various phases of cycles of different amplitudes. BMRs emerging in the rising phase of a cycle can modify the amplitude of the ongoing cycle, while BMRs emerging in later phases will only affect subsequent cycles. In this model, the strongest effect on the subsequent cycle occurs when the rogue BMR emerges around cycle maximum at low latitudes, but the BMR does not need to be strictly cross-equatorial. Active regions emerging as far as 20° from the equator can still have a significant effect. We demonstrate that the combined effect of the magnetic flux, tilt angle, and polarity separation of the BMR on the dynamo is via their contribution to the dipole moment, δ D_{BMR}. Our results indicate that prediction of the amplitude, starting epoch, and duration of a cycle requires an accurate accounting of a broad range of active regions emerging in the previous cycle.

  5. The cost of geothermal energy in the western US region:a portfolio-based approach a mean-variance portfolio optimization of the regions' generating mix to 2013.

    Energy Technology Data Exchange (ETDEWEB)

    Beurskens, Luuk (ECN-Energy Research Centre of the Netherland); Jansen, Jaap C. (ECN-Energy Research Centre of the Netherlands); Awerbuch, Shimon Ph.D. (.University of Sussex, Brighton, UK); Drennen, Thomas E.

    2005-09-01

    Energy planning represents an investment-decision problem. Investors commonly evaluate such problems using portfolio theory to manage risk and maximize portfolio performance under a variety of unpredictable economic outcomes. Energy planners need to similarly abandon their reliance on traditional, ''least-cost'' stand-alone technology cost estimates and instead evaluate conventional and renewable energy sources on the basis of their portfolio cost--their cost contribution relative to their risk contribution to a mix of generating assets. This report describes essential portfolio-theory ideas and discusses their application in the Western US region. The memo illustrates how electricity-generating mixes can benefit from additional shares of geothermal and other renewables. Compared to fossil-dominated mixes, efficient portfolios reduce generating cost while including greater renewables shares in the mix. This enhances energy security. Though counter-intuitive, the idea that adding more costly geothermal can actually reduce portfolio-generating cost is consistent with basic finance theory. An important implication is that in dynamic and uncertain environments, the relative value of generating technologies must be determined not by evaluating alternative resources, but by evaluating alternative resource portfolios. The optimal results for the Western US Region indicate that compared to the EIA target mixes, there exist generating mixes with larger geothermal shares at equal-or-lower expected cost and risk.

  6. Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

    Science.gov (United States)

    Hammond, Victoria J; Morgan, Alwena H; Lauder, Sarah; Thomas, Christopher P; Brown, Sarah; Freeman, Bruce A; Lloyd, Clare M; Davies, Jane; Bush, Andrew; Levonen, Anna-Liisa; Kansanen, Emilia; Villacorta, Luis; Chen, Y Eugene; Porter, Ned; Garcia-Diaz, Yoel M; Schopfer, Francisco J; O'Donnell, Valerie B

    2012-12-07

    12/15-Lipoxygenases (LOXs) in monocytes and macrophages generate novel phospholipid-esterified eicosanoids. Here, we report the generation of two additional families of related lipids comprising 15-ketoeicosatetraenoic acid (KETE) attached to four phosphatidylethanolamines (PEs). The lipids are generated basally by 15-LOX in IL-4-stimulated monocytes, are elevated on calcium mobilization, and are detected at increased levels in bronchoalveolar lavage fluid from cystic fibrosis patients (3.6 ng/ml of lavage). Murine peritoneal macrophages generate 12-KETE-PEs, which are absent in 12/15-LOX-deficient mice. Inhibition of 15-prostaglandin dehydrogenase prevents their formation from exogenous 15-hydroxyeicosatetraenoic acid-PE in human monocytes. Both human and murine cells also generated analogous hydroperoxyeicosatetraenoic acid-PEs. The electrophilic reactivity of KETE-PEs is shown by their Michael addition to glutathione and cysteine. Lastly, both 15-hydroxyeicosatetraenoic acid-PE and 15-KETE-PE activated peroxisome proliferator-activated receptor-γ reporter activity in macrophages in a dose-dependent manner. In summary, we demonstrate novel peroxisome proliferator-activated receptor-γ-activating oxidized phospholipids generated enzymatically by LOX and 15-prostaglandin dehydrogenase in primary monocytic cells and in a human Th2-related lung disease. The lipids are a new family of bioactive mediators from the 12/15-LOX pathway that may contribute to its known anti-inflammatory actions in vivo.

  7. Universities and Economic Development Activities: A UK Regional Comparison

    Science.gov (United States)

    Decter, Moira; Cave, Frank; Rose, Mary; Peers, Gill; Fogg, Helen; Smith, Susan M.

    2011-01-01

    A number of UK universities prioritize economic development or regeneration activities and for some of these universities such activities are the main focus of their knowledge transfer work. This study compares two regions of the UK--the North West and the South East of England--which have very different levels of economic performance.…

  8. Campinas metropolitan region: solid waste management for regional sustainable development; Regiao metropolitana de Campinas: gestao de residuo solido para o desenvolvimento regional sustentavel

    Energy Technology Data Exchange (ETDEWEB)

    Nagle, Elizabeth Camargo; Teixeira, Egle Novaes; Craveiros, Stephanie Grant; London, Pedro; Ferreira, Ronan Goncalves [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Fac. de Engenharia Civil, Arquitetura e Urbanismo; Streb, Cleci Schalemberger [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Fac. de Engenharia Mecanica

    2004-07-01

    Each person generates a lot of residues in their daily activities. The life cycle of residues, production, collection, transportation, treatment and/or end use have negatively impacted the environment. The society has unobserved the limits for the environment and is living with an undesirable pollution level, regarding the capacity of absorbing and recycling residues and materials. Due to these, there is a necessity of rethink the actual model of development adopted by the society. Regarding the global sustainability, the residue management needs to be planned in order to assure the surviving of future generation with life quality. By a theoretic analysis, this article objective is to evaluate the residue management of Campinas Metropolitan Region interference at the regional sustainable development. (author)

  9. Improvement of downscaled rainfall and temperature across generations over the Western Himalayan region of India

    Science.gov (United States)

    Das, L.; Dutta, M.; Akhter, J.; Meher, J. K.

    2016-12-01

    It is a challenging task to create station level (local scale) climate change information over the mountainous locations of Western Himalayan Region (WHR) in India because of limited data availability and poor data quality. In the present study, missing values of station data were handled through Multiple Imputation Chained Equation (MICE) technique. Finally 22 numbers of rain gauge and 16 number of temperature station data having continuous record during 1901­2005 and 1969­2009 period respectively were considered as reference stations for developing downscaled rainfall and temperature time series from five commonly available GCMs in the IPCC's different generation assessment reports namely 2nd, 3rd, 4th and 5th hereafter known as SAR, TAR, AR4 and AR5 respectively. Downscaled models were developed using the combined data from the ERA-interim reanalysis and GCMs historical runs (in spite of forcing were not identical in different generation) as predictor and station level rainfall and temperature as predictands. Station level downscaled rainfall and temperature time series were constructed for five GCMs available in each generation. Regional averaged downscaled time series comprising of all stations was prepared for each model and generation and the downscaled results were compared with observed time series. Finally an Overall Model Improvement Index (OMII) was developed using the downscaling results, which was used to investigate the model improvement across generations as well as the improvement of downscaling results obtained from the Empirical Statistical Downscaling (ESD) methods. In case of temperature, models have improved from SAR to AR5 over the study area. In all most all the GCMs TAR is showing worst performance over the WHR by considering the different statistical indices used in this study. In case of precipitation, no model has shown gradual improvement from SAR to AR5 both for interpolated and downscaled values.

  10. Towards a versatile active wavelength converter for all-optical networks based on quasi-phase matched intra-cavity difference-frequency generation.

    Science.gov (United States)

    Torregrosa, Adrián J; Maestre, Haroldo; Capmany, Juan

    2013-11-18

    The availability of reconfigurable all-optical wavelength converters for an efficient and flexible use of optical resources in WDM (wavelength division multiplexing) networks is still lacking at present. We propose and report preliminary results on a versatile active technique for multiple and tunable wavelength conversions in the 1500-1700 nm spectral region. The technique is based on combining broadband quasi-phase matched intra-cavity parametric single-pass difference-frequency generation close to degeneracy in a diode-pumped tunable laser. A periodically poled stoichiometric lithium tantalate crystal is used as the nonlinear medium, with a parametric pump wave generated in a continuous-wave self-injection locked Cr3+:LiCAF tunable laser operating at around 800 nm.

  11. THE FORMATION AND MAGNETIC STRUCTURES OF ACTIVE-REGION FILAMENTS OBSERVED BY NVST, SDO, AND HINODE

    Energy Technology Data Exchange (ETDEWEB)

    Yan, X. L.; Xue, Z. K.; Wang, J. C.; Xiang, Y. Y.; Kong, D. F.; Yang, L. H. [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650216 (China); Pan, G. M. [College of Mathematics Physics and Information Engineering, Jiaxing University, Jiaxing 314001 (China)

    2015-08-15

    To better understand the properties of solar active-region filaments, we present a detailed study on the formation and magnetic structures of two active-region filaments in active region NOAA 11884 during a period of four days. It is found that the shearing motion of the opposite magnetic polarities and the rotation of the small sunspots with negative polarity play an important role in the formation of two active-region filaments. During the formation of these two active-region filaments, one foot of the filaments was rooted in a small sunspot with negative polarity. The small sunspot rotated not only around another small sunspot with negative polarity, but also around the center of its umbra. By analyzing the nonlinear force-free field extrapolation using the vector magnetic fields in the photosphere, twisted structures were found in the two active-region filaments prior to their eruptions. These results imply that the magnetic fields were dragged by the shearing motion between opposite magnetic polarities and became more horizontal. The sunspot rotation twisted the horizontal magnetic fields and finally formed the twisted active-region filaments.

  12. Measuring the Impact of Wildfire on Active Layer Thickness in a Discontinuous Permafrost region using Interferometric Synthetic Aperture Radar (InSAR)

    Science.gov (United States)

    Michaelides, R. J.; Schaefer, K. M.; Zebker, H. A.; Liu, L.; Chen, J.; Parsekian, A.

    2017-12-01

    In permafrost regions, the active layer is defined as the uppermost portion of the permafrost table that is subject to annual freeze/thaw cycles. The active layer plays a crucial role in surface processes, surface hydrology, and vegetation succession; furthermore, trapped methane, carbon dioxide, and other greenhouse gases in permafrost are released into the atmosphere as permafrost thaws. A detailed understanding of active layer dynamics is therefore critical towards understanding the interactions between permafrost surface processes, freeze/thaw cycles, and climate-especially in regions across the Arctic subject to long-term permafrost degradation. The Yukon-Kuskokwim (YK) delta in southwestern Alaska is a region of discontinuous permafrost characterized by surface lakes, wetlands, and thermokarst depressions. Furthermore, extensive wildfires have burned across the YK delta in 2006, 2007, and 2015, impacting vegetation cover, surface soil moisture, and the active layer. Using data from the ALOS PALSAR, ALOS-2 PALSAR-2, and Sentinel-1A/B space borne synthetic aperture radar (SAR) systems, we generate a series of interferograms over a study site in the YK delta spanning 2007-2011, and 2014-present. Using the ReSALT (Remotely-Sensed Active Layer Thickness) technique, we demonstrate that active layer can be characterized over most of the site from the relative interferometric phase difference due to ground subsidence and rebound associated with the seasonal active layer freeze/thaw cycle. Additionally, we show that this technique successfully discriminates between burned and unburned regions, and can resolve increases in active layer thickness in burned regions on the order of 10's of cms. We use the time series of interferograms to discuss permafrost recovery following wildfire burn, and compare our InSAR observations with GPR and active layer probing data from a 2016 summer field campaign to the study site. Finally, we compare the advantages and disadvantages of

  13. Intrinsically-generated fluctuating activity in excitatory-inhibitory networks

    Science.gov (United States)

    Mastrogiuseppe, Francesca; Ostojic, Srdjan

    2017-01-01

    Recurrent networks of non-linear units display a variety of dynamical regimes depending on the structure of their synaptic connectivity. A particularly remarkable phenomenon is the appearance of strongly fluctuating, chaotic activity in networks of deterministic, but randomly connected rate units. How this type of intrinsically generated fluctuations appears in more realistic networks of spiking neurons has been a long standing question. To ease the comparison between rate and spiking networks, recent works investigated the dynamical regimes of randomly-connected rate networks with segregated excitatory and inhibitory populations, and firing rates constrained to be positive. These works derived general dynamical mean field (DMF) equations describing the fluctuating dynamics, but solved these equations only in the case of purely inhibitory networks. Using a simplified excitatory-inhibitory architecture in which DMF equations are more easily tractable, here we show that the presence of excitation qualitatively modifies the fluctuating activity compared to purely inhibitory networks. In presence of excitation, intrinsically generated fluctuations induce a strong increase in mean firing rates, a phenomenon that is much weaker in purely inhibitory networks. Excitation moreover induces two different fluctuating regimes: for moderate overall coupling, recurrent inhibition is sufficient to stabilize fluctuations; for strong coupling, firing rates are stabilized solely by the upper bound imposed on activity, even if inhibition is stronger than excitation. These results extend to more general network architectures, and to rate networks receiving noisy inputs mimicking spiking activity. Finally, we show that signatures of the second dynamical regime appear in networks of integrate-and-fire neurons. PMID:28437436

  14. Positron-emission tomography of brain regions activated by recognition of familiar music.

    Science.gov (United States)

    Satoh, M; Takeda, K; Nagata, K; Shimosegawa, E; Kuzuhara, S

    2006-05-01

    We can easily recognize familiar music by listening to only one or 2 of its opening bars, but the brain regions that participate in this cognitive processing remain undetermined. We used positron-emission tomography (PET) to study changes in regional cerebral blood flow (rCBF) that occur during listening to familiar music. We used a PET subtraction technique to elucidate the brain regions associated with the recognition of familiar melodies such as well-known nursery tunes. Nonmusicians performed 2 kinds of musical tasks: judging the familiarity of musical pieces (familiarity task) and detecting deliberately altered notes in the pieces (alteration-detecting task). During the familiarity task, bilateral anterior portions of bilateral temporal lobes, superior temporal regions, and parahippocampal gyri were activated. The alteration-detecting task bilaterally activated regions in the precunei, superior/inferior parietal lobules, and lateral surface of frontal lobes, which seemed to show a correlation with the analysis of music. We hypothesize that during the familiarity task, activated brain regions participate in retrieval from long-term memory and verbal and emotional processing of familiar melodies. Our results reinforced the hypothesis reported in the literature as a result of group and case studies, that temporal lobe regions participate in the recognition of familiar melodies.

  15. Crossmodal Activation of Visual Object Regions for Auditorily Presented Concrete Words

    Directory of Open Access Journals (Sweden)

    Jasper J F van den Bosch

    2011-10-01

    Full Text Available Dual-coding theory (Paivio, 1986 postulates that the human mind represents objects not just with an analogous, or semantic code, but with a perceptual representation as well. Previous studies (eg, Fiebach & Friederici, 2004 indicated that the modality of this representation is not necessarily the one that triggers the representation. The human visual cortex contains several regions, such as the Lateral Occipital Complex (LOC, that respond specifically to object stimuli. To investigate whether these principally visual representations regions are also recruited for auditory stimuli, we presented subjects with spoken words with specific, concrete meanings (‘car’ as well as words with abstract meanings (‘hope’. Their brain activity was measured with functional magnetic resonance imaging. Whole-brain contrasts showed overlap between regions differentially activated by words for concrete objects compared to words for abstract concepts with visual regions activated by a contrast of object versus non-object visual stimuli. We functionally localized LOC for individual subjects and a preliminary analysis showed a trend for a concreteness effect in this region-of-interest on the group level. Appropriate further analysis might include connectivity and classification measures. These results can shed light on the role of crossmodal representations in cognition.

  16. Density of Plutonium Turnings Generated from Machining Activities

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, John Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vigil, Duane M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Jachimowski, Thomas A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Archuleta, Alonso [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Arellano, Gerald Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Melton, Vince Lee [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-20

    The purpose of this project was to determine the density of plutonium (Pu) turnings generated from the range of machining activities, using both surrogate material and machined Pu turnings. Verify that 500 grams (g) of plutonium will fit in a one quart container using a surrogate equivalent volume and that 100 grams of Pu will fit in a one quart Savy container.

  17. Ocean Pollution as a Result of Onshore Offshore Petroleum Activities in the African Gulf of Guinea Region

    Science.gov (United States)

    Abubakar, B.

    2007-05-01

    increasing cases of pollution of farmlands, rivers, wells and the environment in general. Apart from all these, what is even becoming more worrisome is that none of all these oil firms operating in the region is able to account on how it disposes its industrial toxic waste generated as a result of its industrial activities within the region. Finally Geological strata are adversely destroyed by seismographic activities, Sea creatures are destroyed by oil pollution and Means of livelihood of revering dwellers are often threatened by pollution. RECOMMENDATIONS After identifying how the pollution in the Gulf of Guinea region is increasing in relation to the increasing petroleum activities, I have come up with the following suggestions/recommendations. 1. AFRICAN UNION RESOLUTION The Organization of the Petroleum Exporting Countries (OPEC) in conjunction with the International Atomic Energy Agency (IAEA) should use their capacity to be able to influence the African Union (AU) to pass a resolution banning the illegal dumping of radioactive waste, Gas flaring and Costal bunkering in this part of the world. 2. RESEARCH AND INVESTIGATION The Organization of the Petroleum Exporting Countries, in conjunction with the United Nations Environmental Agency, the International Atomic Energy Agency and with the corporation of the African Union should send team of researchers to come and investigate this trend on petroleum pollution in the Gulf of Guinea region and proffer possible solutions in checking the menace.

  18. Armenia as a Regional Centre for Astronomy for Development activities

    Science.gov (United States)

    Mickaelian, A.

    2015-03-01

    The Byurakan Astrophysical Observatory (BAO, Armenia, http://www.bao.am) are among the candidate IAU Regional Nodes for Astronomy for Development activities. It is one of the main astronomical centers of the former Soviet Union and the Middle East region. At present there are 48 qualified researchers at BAO, including six Doctors of Science and 30 PhDs. Five important observational instruments are installed at BAO, the larger ones being 2.6m Cassegrain (ZTA-2.6) and 1m Schmidt (the one that provided the famous Markarian survey). BAO is regarded as a national scientific-educational center, where a number of activities are being organized, such as: international conferences (4 IAU symposia and 1 IAU colloquium, JENAM-2007, etc.), small workshops and discussions, international summer schools (1987, 2006, 2008 and 2010), and Olympiads. BAO collaborates with scientists from many countries. The Armenian Astronomical Society (ArAS, http://www.aras.am/) is an NGO founded in 2001; it has 93 members and it is rather active in the organization of educational, amateur, popular, promotional and other matters. The Armenian Virtual Observatory (ArVO, http://www.aras.am/Arvo/arvo.htm) is one of the 17 national VO projects forming the International Virtual Observatories Alliance (IVOA) and is the only VO project in the region serving also for educational purposes. A number of activities are planned, such as management, coordination and evaluation of the IAU programs in the area of development and education, establishment of the new IAU endowed lectureship program and organization of seminars and public lectures, coordination and initiation of fundraising activities for astronomy development, organization of regional scientific symposia, conferences and workshops, support to Galileo Teacher Training Program (GTTP), production/publication of educational and promotional materials, etc.

  19. Regional differences in commuting activities of inhabitants in the Tokyo metropolitan suburb

    Directory of Open Access Journals (Sweden)

    Masaki Kawase

    2004-12-01

    Full Text Available The purpose of this study is to elucidate gender differences and regional differences of co-mmuting activities by inhabitants in Japanese metropolitan suburbs. I found the different parts by districts in the metropolitan suburb. Regional factors cause gender differences in commuting activities and result in regional differences: In residential areas, inhabitants who work in metropolitan centers occupy much of the population. In older built-up areas, there are many “local” persons. In rural areas, motorization is progressing because access to rail-roads has been inconvenient. These regional factors influence the behavioral characteristics of commuting by married men, married women, never married men and never married women.

  20. Commercially Available Activated Carbon Fiber Felt Enables Efficient Solar Steam Generation.

    Science.gov (United States)

    Li, Haoran; He, Yurong; Hu, Yanwei; Wang, Xinzhi

    2018-03-21

    Sun-driven steam generation is now possible and has the potential to help meet future energy needs. Current technologies often use solar condensers to increase solar irradiance. More recently, a technology for solar steam generation that uses heated surface water and low optical concentration is reported. In this work, a commercially available activated carbon fiber felt is used to generate steam efficiently under one sun illumination. The evaporation rate and solar conversion efficiency reach 1.22 kg m -2 h -1 and 79.4%, respectively. The local temperature of the evaporator with a floating activated carbon fiber felt reaches 48 °C. Apart from the high absorptivity (about 94%) of the material, the evaporation performance is enhanced thanks to the well-developed pores for improved water supply and steam escape and the low thermal conductivity, which enables reduced bulk water temperature increase. This study helps to find a promising material for solar steam generation using a water evaporator that can be produced economically (∼6 $/m 2 ) with long-term stability.

  1. Perceived built environment and physical activity in U.S. women by sprawl and region.

    Science.gov (United States)

    Troped, Philip J; Tamura, Kosuke; Whitcomb, Heather A; Laden, Francine

    2011-11-01

    A number of studies have demonstrated relationships between the perceived built environment and physical activity among adults. However, little is known about whether these associations differ by U.S. region and level of urban sprawl. To examine associations between the perceived built environment and physical activity in U.S. women by region and urban sprawl. Nurses' Health Study II participants (N=68,968) completed four perceived neighborhood environment survey items in 2005. Logistic regression was used to estimate associations with meeting physical activity recommendations, adjusting for demographic and weight-status variables, and stratifying by region and sprawl. Data analyses were completed in 2011. Perceived proximity to shops/stores was positively associated with physical activity across regions and levels of sprawl (ORs=1.21-1.46). Perceived access to recreation facilities was also a positive physical activity correlate in most region-sprawl strata, with strongest relationships found in the West (ORs=1.31-1.70). Perceived crime and presence of sidewalks did not show statistically significant associations with physical activity in most region-sprawl strata, although ORs for perceived crime showed a consistent pattern of negative associations (ORs=0.60-0.95). A higher number of positive environmental attributes was associated with a greater odds of meeting physical activity recommendations. Findings indicate that perceived proximity to shops/stores and access to recreation facilities are important correlates of physical activity for women, irrespective of region or sprawl. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  2. Entropy Generation and Human Aging: Lifespan Entropy and Effect of Physical Activity Level

    Science.gov (United States)

    Silva, Carlos; Annamalai, Kalyan

    2008-06-01

    The first and second laws of thermodynamics were applied to biochemical reactions typical of human metabolism. An open-system model was used for a human body. Energy conservation, availability and entropy balances were performed to obtain the entropy generated for the main food components. Quantitative results for entropy generation were obtained as a function of age using the databases from the U.S. Food and Nutrition Board (FNB) and Centers for Disease Control and Prevention (CDC), which provide energy requirements and food intake composition as a function of age, weight and stature. Numerical integration was performed through human lifespan for different levels of physical activity. Results were presented and analyzed. Entropy generated over the lifespan of average individuals (natural death) was found to be 11,404 kJ/ºK per kg of body mass with a rate of generation three times higher on infants than on the elderly. The entropy generated predicts a life span of 73.78 and 81.61 years for the average U.S. male and female individuals respectively, which are values that closely match the average lifespan from statistics (74.63 and 80.36 years). From the analysis of the effect of different activity levels, it is shown that entropy generated increases with physical activity, suggesting that exercise should be kept to a “healthy minimum” if entropy generation is to be minimized.

  3. Abundance variations in solar active regions

    Science.gov (United States)

    Strong, K. T.; Lemen, J. R.; Linford, G. A.

    1991-01-01

    The diversity in the published values of coronal abundances is unsettling, especially as the range of results seems to be beyond the quoted uncertainties. Measurements of the relative abundance of iron and neon derived from soft X-ray spectra of active regions are presented. From a data base of over 200 spectra taken by the Solar Maximum Mission Flat Crystal Spectrometer, it is found that the relative abundance can vary by as much as a factor of about 7 and can change on timescales of less than 1 h.

  4. Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight.

    Science.gov (United States)

    Purohit, Rituraj

    2014-01-01

    KIT receptor is the prime target in gastrointestinal stromal tumor (GISTs) therapy. Second generation inhibitor, Sunitinib, binds to an inactivated conformation of KIT receptor and stabilizes it in order to prevent tumor formation. Here, we investigated the dynamic behavior of wild type and mutant D816H KIT receptor, and emphasized the extended A-loop (EAL) region (805-850) by conducting molecular dynamics simulation (∼100 ns). We analyzed different properties such as root mean square cutoff or deviation, root mean square fluctuation, radius of gyration, solvent-accessible surface area, hydrogen bonding network analysis, and essential dynamics. Apart from this, clustering and cross-correlation matrix approach was used to explore the conformational space of the wild type and mutant EAL region of KIT receptor. Molecular dynamics analysis indicated that mutation (D816H) was able to alter intramolecular hydrogen bonding pattern and affected the structural flexibility of EAL region. Moreover, flexible secondary elements, specially, coil and turns were dominated in EAL region of mutant KIT receptor during simulation. This phenomenon increased the movement of EAL region which in turn helped in shifting the equilibrium towards the active kinase conformation. Our atomic investigation of mutant KIT receptor which emphasized on EAL region provided a better insight into the understanding of Sunitinib resistance mechanism of KIT receptor and would help to discover new therapeutics for KIT-based resistant tumor cells in GIST therapy.

  5. Functional overlap of top-down emotion regulation and generation: an fMRI study identifying common neural substrates between cognitive reappraisal and cognitively generated emotions.

    Science.gov (United States)

    Otto, Benjamin; Misra, Supriya; Prasad, Aditya; McRae, Kateri

    2014-09-01

    One factor that influences the success of emotion regulation is the manner in which the regulated emotion was generated. Recent research has suggested that reappraisal, a top-down emotion regulation strategy, is more effective in decreasing self-reported negative affect when emotions were generated from the top-down, versus the bottom-up. On the basis of a process overlap framework, we hypothesized that the neural regions active during reappraisal would overlap more with emotions that were generated from the top-down, rather than from the bottom-up. In addition, we hypothesized that increased neural overlap between reappraisal and the history effects of top-down emotion generation would be associated with increased reappraisal success. The results of several analyses suggested that reappraisal and emotions that were generated from the top-down share a core network of prefrontal, temporal, and cingulate regions. This overlap is specific; no such overlap was observed between reappraisal and emotions that were generated in a bottom-up fashion. This network consists of regions previously implicated in linguistic processing, cognitive control, and self-relevant appraisals, which are processes thought to be crucial to both reappraisal and top-down emotion generation. Furthermore, individuals with high reappraisal success demonstrated greater neural overlap between reappraisal and the history of top-down emotion generation than did those with low reappraisal success. The overlap of these key regions, reflecting overlapping processes, provides an initial insight into the mechanism by which generation history may facilitate emotion regulation.

  6. Entropy Generation and Human Aging: Lifespan Entropy and Effect of Physical Activity Level

    Directory of Open Access Journals (Sweden)

    Kalyan Annamalai

    2008-06-01

    Full Text Available The first and second laws of thermodynamics were applied to biochemical reactions typical of human metabolism. An open-system model was used for a human body. Energy conservation, availability and entropy balances were performed to obtain the entropy generated for the main food components. Quantitative results for entropy generation were obtained as a function of age using the databases from the U.S. Food and Nutrition Board (FNB and Centers for Disease Control and Prevention (CDC, which provide energy requirements and food intake composition as a function of age, weight and stature. Numerical integration was performed through human lifespan for different levels of physical activity. Results were presented and analyzed. Entropy generated over the lifespan of average individuals (natural death was found to be 11,404 kJ/ºK per kg of body mass with a rate of generation three times higher on infants than on the elderly. The entropy generated predicts a life span of 73.78 and 81.61 years for the average U.S. male and female individuals respectively, which are values that closely match the average lifespan from statistics (74.63 and 80.36 years. From the analysis of the effect of different activity levels, it is shown that entropy generated increases with physical activity, suggesting that exercise should be kept to a “healthy minimum” if entropy generation is to be minimized.

  7. Radiative and magnetic properties of solar active regions. II. Spatially resolved analysis of O V 62.97 nm transition region emission

    Science.gov (United States)

    Fludra, A.; Warren, H.

    2010-11-01

    Context. Global relationships between the photospheric magnetic flux and the extreme ultraviolet emission integrated over active region area have been studied in a previous paper by Fludra & Ireland (2008, A&A, 483, 609). Spatially integrated EUV line intensities are tightly correlated with the total unsigned magnetic flux, and yet these global power laws have been shown to be insufficient for accurately determining the coronal heating mechanism owing to the mathematical ill-conditioning of the inverse problem. Aims: Our aim is to establish a relationship between the EUV line intensities and the photospheric magnetic flux density on small spatial scales in active regions and investigate whether it provides a way of identifying the process that heats the coronal loops. Methods: We compare spatially resolved EUV transition region emission and the photospheric magnetic flux density. This analysis is based on the O V 62.97 nm line recorded by the SOHO Coronal Diagnostic Spectrometer (CDS) and SOHO MDI magnetograms for six solar active regions. The magnetic flux density ϕ is converted to a simulated O V intensity using a model relationship I(ϕ, L) = Cϕδ Lλ, where the loop length L is obtained from potential magnetic field extrapolations. This simulated spatial distribution of O V intensities is convolved with the CDS instrument's point spread function and compared pixel by pixel with the observed O V line intensity. Parameters δ and λ are derived to give the best fit for the observed and simulated intensities. Results: Spatially-resolved analysis of the transition region emission reveals the complex nature of the heating processes in active regions. In some active regions, particularly large, local intensity enhancements up to a factor of five are present. When areas with O V intensities above 3000 erg cm-2 s-1 sr-1 are ignored, a power law has been fitted to the relationship between the local O V line intensity and the photospheric magnetic flux density in each

  8. On the relation of Hsub(α) plage brightness variations in solar active regions

    International Nuclear Information System (INIS)

    Ogir', M.B.

    1980-01-01

    The variations of hydrogen plage brightnesses in seven spot groups belonging to five active regions are discussed. The observations were made on the Crimean observatory coronograph in 1974 and 1977. The correlation in brightness variations of plages situated in the regions of growing magnetic field was obtained. This was observed in the plages on one spot group as well as in the different groups removing on about 27x10 4 km. In developed groups correlations are mainly seen within a spot group and they are expressed better during flares. The correlations of brightnesses are changing during the active region evolution. Three days observations showed good brightness correlations of all plages in the growing magnetic field region and their decrease that can be explained by the field weakening during natural active region evolution or by the strong flare influence. The existence of the simultaneous variations of brightness in the regions with the growing magnetic field speaks in favour of the simultaneous carring-out of magnetic field or its disturbances into the chromosphere [ru

  9. In vitro effects of recombinant activated factor VII on thrombin generation and coagulation following inhibition of platelet procoagulant activity by prasugrel.

    Science.gov (United States)

    Mazzeffi, Michael; Szlam, Fania; Jakubowski, Joseph A; Tanaka, Kenichi A; Sugidachi, Atsuhiro; Levy, Jerrold H

    2013-07-01

    Prasugrel is a thienopyridyl P2Y12 antagonist with potent antiplatelet effects. At present, little is known about its effects on thrombin generation or what strategies may emergently reverse its anticoagulant effects. In the current study we evaluated whether recombinant activated factor VII may reverse prasugrel induced effects and increase thrombin generation in an in vitro model. The effect of prasugrel active metabolite, PAM (R-138727), was evaluated on platelet aggregation, thrombin generation, and rotational thromboelastometry parameters using blood from 20 healthy volunteers. Additionally, we evaluated the effects of adenosine diphosphate (ADP) and recombinant activated factor VII on restoring these parameters towards baseline values. PAM reduced maximum platelet aggregation and led to platelet disaggregation. It also decreased peak thrombin, increased lag time, and increased time to peak thrombin. Treatment with recombinant activated factor VII restored all three parameters of thrombin generation towards baseline. ADP decreased lag time and time to peak thrombin, but had no effect on peak thrombin. When recombinant activated factor VII and ADP were combined they had a greater effect on thrombin parameters than either drug alone. PAM also increased thromboelastometric clotting time and clot formation time, but had no effect on maximum clot firmness. Treatment with either recombinant activated factor VII or ADP restored these values towards baseline. Recombinant activated factor VII restores thrombin generation in the presence of PAM. In patients taking prasugrel with life-threatening refractory bleeding it has the potential to be a useful therapeutic approach. Additional clinical studies are needed to validate our findings. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Seismo-active faults in the Banat region, Romania

    International Nuclear Information System (INIS)

    Oros, E.

    2002-01-01

    The knowledge of the seismo-active faults represents a very important element in every seismic hazard analysis. The main purpose of our paper is to best define the seismo-active faults of the Banat Region. The region is characterized by high seismicity, with important focus of strong earthquakes (I>VII MSK degrees). The quality of the historical data is many times too weak for being used in seismotectonic studies. Thus a correlation between historical and recent seismicity must be done. In our study, several seismic sequences that occurred in the Banat Region, are analysed in detail. The distribution of the epicenters and the correlation tectonics-fault plane solutions reveal important seismotectonic features. The obtained results complete the image of the historical seismicity and offer important information for the future studies of seismic hazard. These results are also very important for the development and configuration of the Banat Seismic Network. The recent seismic activity was analysed for 1995-2002 period, when over 2500 local earthquakes were recorded (M min = 0.5 and M max = 4.8). 26 fault plane solutions were determined (first wave polarities method with additional amplitude constraints). For the earthquakes that occurred at the national border with Yugoslavia and Hungary we used the data from international bulletins. The main seismic sequences were concentrated in seven important zones: Moldova Noua, Herculane Spa - Orsova, Petrosani - Western Jiu Valey, Banloc, Voiteg, Timisoara East and Timisoara North. We also located a small seismic sequence in the Baia de Arama - Tirgu Jiu area. The results were correlated with the faults and major structures, with macroseismic field of the strongest local earthquakes, too. The seismic hazard sources and faults from outside the country (Hungary an Yugoslavia) are pointed out. (authors)

  11. Macroeconomic dataset for generating macroeconomic volatility among selected countries in the Asia Pacific region.

    Science.gov (United States)

    Chow, Yee Peng; Muhammad, Junaina; Amin Noordin, Bany Ariffin; Cheng, Fan Fah

    2018-02-01

    This data article provides macroeconomic data that can be used to generate macroeconomic volatility. The data cover a sample of seven selected countries in the Asia Pacific region for the period 2004-2014, including both developing and developed countries. This dataset was generated to enhance our understanding of the sources of macroeconomic volatility affecting the countries in this region. Although the Asia Pacific region continues to remain as the most dynamic part of the world's economy, it is not spared from various sources of macroeconomic volatility through the decades. The reported data cover 15 types of macroeconomic data series, representing three broad categories of indicators that can be used to proxy macroeconomic volatility. They are indicators that account for macroeconomic volatility (i.e. volatility as a macroeconomic outcome), domestic sources of macroeconomic volatility and external sources of macroeconomic volatility. In particular, the selected countries are Malaysia, Thailand, Indonesia and Philippines, which are regarded as developing countries, while Singapore, Japan and Australia are developed countries. Despite the differences in level of economic development, these countries were affected by similar sources of macroeconomic volatility such as the Asian Financial Crisis and the Global Financial Crisis. These countries were also affected by other similar external turbulence arising from factors such as the global economic slowdown, geopolitical risks in the Middle East and volatile commodity prices. Nonetheless, there were also sources of macroeconomic volatility which were peculiar to certain countries only. These were generally domestic sources of volatility such as political instability (for Thailand, Indonesia and Philippines), natural disasters and anomalous weather conditions (for Thailand, Indonesia, Philippines, Japan and Australia) and over-dependence on the electronic sector (for Singapore).

  12. Physical activities of students in special primary schools in the central Bohemian region

    OpenAIRE

    Beznosova, Irina

    2011-01-01

    1 Abstract Title of the thesis: Physical activities of students in special primary schools in the central Bohemian region Aim of the study: The aim of the thesis is a comprehensive survey of physical activities provided by special primary schools in the Central Bohemian region. Method: We used a method of an empirical research. We studied a representative sample of special primary schools located in the Central Bohemia region in order to ascertain characteristics of the objects of observation...

  13. Early evolution of an X-ray emitting solar active region

    International Nuclear Information System (INIS)

    Wolfson, C.J.; Acton, L.W.; Leibacher, J.W.; Roethig, D.T.

    1977-01-01

    The birth and early evolution of a solar active region has been investigated using X-ray observations from the Lockheed Mapping X-Ray Heliometer on board the OSO-8 spacecraft. X-ray emission is observed within three hours of the first detection of Hα plage. At that time, a plasma temperature of 4 x 10 6 K in a region having a density of the order of 10 10 cm -3 is inferred. During the fifty hours following birth almost continuous flares or flare-like X-ray bursts are superimposed on a monotonically increasing base level of X-ray emission produced by plasma with a temperature of the order 3 x 10 6 K. If it is assumed that the X-rays result from heating due to dissipation of current systems or magnetic field reconnection, it can be concluded that flare-like X-ray emission soon after active region birth implies that the magnetic field probably emerges in a stressed or complex configuration. (Auth.)

  14. Generating original ideas: The neural underpinning of originality.

    Science.gov (United States)

    Mayseless, Naama; Eran, Ayelet; Shamay-Tsoory, Simone G

    2015-08-01

    One of the key aspects of creativity is the ability to produce original ideas. Originality is defined in terms of the novelty and rarity of an idea and is measured by the infrequency of the idea compared to other ideas. In the current study we focused on divergent thinking (DT) - the ability to produce many alternate ideas - and assessed the neural pathways associated with originality. Considering that generation of original ideas involves both the ability to generate new associations and the ability to overcome automatic common responses, we hypothesized that originality would be associated with activations in regions related to associative thinking, including areas of the default mode network (DMN) such as medial prefrontal areas, as well as with areas involved in cognitive control and inhibition. Thirty participants were scanned while performing a DT task that required the generation of original uses for common objects. The results indicate that the ability to produce original ideas is mediated by activity in several regions that are part of the DMN including the medial prefrontal cortex (mPFC) and the posterior cingulate cortex (PCC). Furthermore, individuals who are more original exhibited enhanced activation in the ventral anterior cingulate cortex (vACC), which was also positively coupled with activity in the left occipital-temporal area. These results are in line with the dual model of creativity, according to which original ideas are a product of the interaction between a system that generates ideas and a control system that evaluates these ideas. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Design and Activation of a LOX/GH Chemical Steam Generator

    Science.gov (United States)

    Saunders, G. P.; Mulkey, C. A.; Taylor, S. A.

    2009-01-01

    The purpose of this paper is to give a detailed description of the design and activation of the LOX/GH fueled chemical steam generator installed in Cell 2 of the E3 test facility at Stennis Space Center, MS (SSC). The steam generator uses a liquid oxygen oxidizer with gaseous hydrogen fuel. The combustion products are then quenched with water to create steam at pressures from 150 to 450 psig at temperatures from 350 to 750 deg F (from saturation to piping temperature limits).

  16. Stored Energy Balance for Distributed PV-Based Active Generators in an AC Microgrid

    DEFF Research Database (Denmark)

    Aldana, Nelson Leonardo Diaz; Wu, Dan; Dragicevic, Tomislav

    2015-01-01

    In this paper, a decentralized strategy based on fuzzy logic is proposed for balancing the state of charge of the energy storage units for distributed PV-based active generators. The proposed method, weights the action of conventional droop control loops for privileging the charge of the energy...... expandable and can be applied to a several number of power generators interconnected in a microgrid. Frequency and voltage bus signaling is used in order to coordinate the control operation mode between units. Simulation results in a low-voltage, three-phase, islanded AC microgrid show the feasibility...... of the proposed method and its applicability even for several active generators....

  17. Finite element calculation of fields around the end region of a turbine generator test rig

    Energy Technology Data Exchange (ETDEWEB)

    Eastham, J.F.; Rodger, D.; Lai, H.C.; Nouri, H. (Univ. of Bath (United Kingdom))

    1993-03-01

    Under transient conditions, most often caused by faults in the power system, unbalanced load is presented to a turbine generator. This gives rise to airgap fields which do not travel at the speed of the rotor, and cause induced currents which occur in the solid steel surface. This can cause high local heating. The current path is generally in the axial direction of the machine but the distribution in the end region is not so well known. Here, comparisons are drawn between the use of surface impedance elements and volume elements when modeling a test rig using the MEGA package. The test rig is representative of a turbine generator. The work is supported by practical measurements.

  18. Numerical simulation of convective generated gravity waves in the stratosphere and MLT regions.

    Science.gov (United States)

    Heale, C. J.; Snively, J. B.

    2017-12-01

    Convection is an important source of gravity wave generation, especially in the summer tropics and midlatitudes, and coherent wave fields above convection are now routinely measured in the stratosphere and mesosphere [e.g. Hoffmann et al., JGR, 118, 2013; Gong et al., JGR, 120, 2015; Perwitasari et al., GRL, 42, 22, 2016]. Numerical studies have been performed to investigate the generation mechanisms, source spectra, and their effects on the middle and upper atmosphere [e.g. Fovell et al., AMS, 49,16, 1992; Alexander and Holton, Atmos. Chem. Phys., 4 2004; Vincent et al., JGR, 1118, 2013], however there is still considerable work needed to fully describe these parameters. GCMs currently lack the resolution to explicitly simulate convection generation and rely on simplified parameterizations while full cloud resolving models are computationally expensive and often only extend into the stratosphere. More recent studies have improved the realism of these simulations by using radar derived precipitation rates to drive latent heating in models that simulate convection [Grimsdell et al., AMS, 67, 2010; Stephan and Alexander., J. Adv. Model. Earth. Syst, 7, 2015], however they too only consider wave propagation in the troposphere and stratosphere. We use a 2D nonlinear, fully compressible model [Snively and Pasko., JGR, 113, 2008] to excite convectively generated waves, based on NEXRAD radar data, using the Stephan and Alexander [2015] algorithms. We study the propagation, and spectral evolution of the generated waves up into the MLT region. Ambient atmosphere parameters are derived from observations and MERRA-2 reanalysis data, and stratospheric (AIRS) and mesospheric (Lidar, OH airglow) observations enable comparisons with simulation results.

  19. [Cellular mechanism of the generation of spontaneous activity in gastric muscle].

    Science.gov (United States)

    Nakamura, Eri; Kito, Yoshihiko; Fukuta, Hiroyasu; Yanai, Yoshimasa; Hashitani, Hikaru; Yamamoto, Yoshimichi; Suzuki, Hikaru

    2004-03-01

    In gastric smooth muscles, interstitial cells of Cajal (ICC) might be the pacemaker cells of spontaneous activities since ICC are rich in mitochondria and are connected with smooth muscle cells via gap junctions. Several types of ICC are distributed widely in the stomach wall. A group of ICC distributed in the myenteric layer (ICC-MY) were the pacemaker cells of gastrointestinal smooth muscles. Pacemaker potentials were generated in ICC-MY, and the potentials were conducted to circular smooth muscles to trigger slow waves and also conducted to longitudinal muscles to form follower potentials. In circular muscle preparations, interstitial cells distributed within muscle bundles (ICC-IM) produced unitary potentials, which were conducted to circular muscles to form slow potentials by summation. In mutant mice lacking inositol trisphosphate (IP(3)) receptor, slow waves were absent in gastric smooth muscles. The generation of spontaneous activity was impaired by the inhibition of Ca(2+)-release from internal stores through IP(3) receptors, inhibition of mitochondrial Ca(2+)-handling with proton pump inhibitors, and inhibition of ATP-sensitive K(+)-channels at the mitochondrial inner membrane. These results suggested that mitochondrial Ca(2+)-handling causes the generation of spontaneous activity in pacemaker cells. Possible involvement of protein kinase C (PKC) in the Ca(2+) signaling system was also suggested.

  20. Active and reactive power neurocontroller for grid-connected photovoltaic generation system

    Directory of Open Access Journals (Sweden)

    I. Abadlia

    2016-03-01

    Full Text Available Many researchers have contributed to the development of a firm foundation for analysis and design of control applications in grid-connected renewable energy sources. This paper presents an intelligent control algorithm fond on artificial neural networks for active and reactive power controller in grid-connected photovoltaic generation system. The system is devices into two parts in which each part contains an inverter with control algorithm. A DC/DC converter in output voltage established by control magnitude besides maximum power point tracker algorithm always finds optimal power of the PV array in use. A DC/AC hysteresis inverter designed can synchronize a sinusoidal current output with the grid voltage and accurate an independent active and reactive power control. Simulation results confirm the validation of the purpose. Neurocontroller based active and reactive power presents an efficiency control that guarantees good response to the steps changing in active and reactive power with an acceptable current/voltage synchronism. In this paper the power circuit and the control system of the presented grid-connected photovoltaic generation system is simulated and tested by MatLab/Simulink.

  1. Propagating wave in active region-loops, located over the solar disk observed by the Interface Region Imaging Spectrograph

    Science.gov (United States)

    Zhang, B.; Hou, Y. J.; Zhang, J.

    2018-03-01

    Aims: We aim to ascertain the physical parameters of a propagating wave over the solar disk detected by the Interface Region Imaging Spectrograph (IRIS). Methods: Using imaging data from the IRIS and the Solar Dynamic Observatory (SDO), we tracked bright spots to determine the parameters of a propagating transverse wave in active region (AR) loops triggered by activation of a filament. Deriving the Doppler velocity of Si IV line from spectral observations of IRIS, we have determined the rotating directions of active region loops which are relevant to the wave. Results: On 2015 December 19, a filament was located on the polarity inversion line of the NOAA AR 12470. The filament was activated and then caused a C1.1 two-ribbon flare. Between the flare ribbons, two rotation motions of a set of bright loops were observed to appear in turn with opposite directions. Following the end of the second rotation, a propagating wave and an associated transverse oscillation were detected in these bright loops. In 1400 Å channel, there was bright material flowing along the loops in a wave-like manner, with a period of 128 s and a mean amplitude of 880 km. For the transverse oscillation, we tracked a given loop and determine the transverse positions of the tracking loop in a limited longitudinal range. In both of 1400 Å and 171 Å channels, approximately four periods are distinguished during the transverse oscillation. The mean period of the oscillation is estimated as 143 s and the displacement amplitude as between 1370 km and 690 km. We interpret these oscillations as a propagating kink wave and obtain its speed of 1400 km s-1. Conclusions: Our observations reveal that a flare associated with filament activation could trigger a kink propagating wave in active region loops over the solar disk. Movies associated to Figs. 1-4 are available at http://https://www.aanda.org

  2. Using Magnetic Helicity Diagnostics to Determine the Nature of Solar Active-Region Formation

    Science.gov (United States)

    Georgoulis, Manolis K.

    Employing a novel nonlinear force-free (NLFF) method that self-consistently infers instantaneous free magnetic-energy and relative magnetic-helicity budgets from single photospheric vector magnetograms, we recently constructed the magnetic energy-helicity (EH) diagram of solar active regions. The EH diagram implies dominant relative helicities of left-handed or right-handed chiralities for the great majority of active regions. The amplitude (budget) of these helicities scales monotonically with the free magnetic energy. This constructive, strongly preferential accumulation of a certain sense of magnetic helicity seems to disqualify recently proposed mechanisms relying on a largely random near-surface convection for the formation of the great majority of active regions. The existing qualitative formation mechanism for these regions remains the conventional Omega-loop emergence following a buoyant ascension from the bottom of the convection zone. However, exceptions to this rule include even eruptive active regions: NOAA AR 11283 is an obvious outlier to the EH diagram, involving significant free magnetic energy with a small relative magnetic helicity. Relying on a timeseries of vector magnetograms of this region, our methodology shows nearly canceling amounts of both senses of helicity and an overall course from a weakly left-handed to a weakly right-handed structure, in the course of which a major eruption occurs. For this and similarly behaving active regions the latest near-surface formation scenario might conceivably be employed successfully. Research partially supported by the EU Seventh Framework Programme under grant agreement No. PIRG07-GA-2010-268245 and by the European Union Social Fund (ESF) and Greek national funds through the Operational Program "Education and Lifelong Learning" of the National Strategic Reference Framework (NSRF) - Research Funding Program: Thales. Investing in knowledge society through the European Social Fund.

  3. Fabrication Processes to Generate Concentration Gradients in Polymer Solar Cell Active Layers

    Science.gov (United States)

    Inaba, Shusei; Vohra, Varun

    2017-01-01

    Polymer solar cells (PSCs) are considered as one of the most promising low-cost alternatives for renewable energy production with devices now reaching power conversion efficiencies (PCEs) above the milestone value of 10%. These enhanced performances were achieved by developing new electron-donor (ED) and electron-acceptor (EA) materials as well as finding the adequate morphologies in either bulk heterojunction or sequentially deposited active layers. In particular, producing adequate vertical concentration gradients with higher concentrations of ED and EA close to the anode and cathode, respectively, results in an improved charge collection and consequently higher photovoltaic parameters such as the fill factor. In this review, we relate processes to generate active layers with ED–EA vertical concentration gradients. After summarizing the formation of such concentration gradients in single layer active layers through processes such as annealing or additives, we will verify that sequential deposition of multilayered active layers can be an efficient approach to remarkably increase the fill factor and PCE of PSCs. In fact, applying this challenging approach to fabricate inverted architecture PSCs has the potential to generate low-cost, high efficiency and stable devices, which may revolutionize worldwide energy demand and/or help develop next generation devices such as semi-transparent photovoltaic windows. PMID:28772878

  4. Activation of dormant ovarian follicles to generate mature eggs.

    Science.gov (United States)

    Li, Jing; Kawamura, Kazuhiro; Cheng, Yuan; Liu, Shuang; Klein, Cynthia; Liu, Shu; Duan, En-Kui; Hsueh, Aaron J W

    2010-06-01

    Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are activated for development. Genetically modified mouse models with oocyte-specific deletion of genes in the PTEN-PI3K-Akt-Foxo3 pathway exhibited premature activation of all dormant follicles. Using an inhibitor of the Phosphatase with TENsin homology deleted in chromosome 10 (PTEN) phosphatase and a PI3K activating peptide, we found that short-term treatment of neonatal mouse ovaries increased nuclear exclusion of Foxo3 in primordial oocytes. After transplantation under kidney capsules of ovariectomized hosts, treated follicles developed to the preovulatory stage with mature eggs displaying normal epigenetic changes of imprinted genes. After in vitro fertilization and embryo transfer, healthy progeny with proven fertility were delivered. Human ovarian cortical fragments from cancer patients were also treated with the PTEN inhibitor. After xeno-transplantation to immune-deficient mice for 6 months, primordial follicles developed to the preovulatory stage with oocytes capable of undergoing nuclear maturation. Major differences between male and female mammals are unlimited number of sperm and paucity of mature oocytes. Thus, short-term in vitro activation of dormant ovarian follicles after stimulation of the PI3K-Akt pathway allows the generation of a large supply of mature female germ cells for future treatment of infertile women with a diminishing ovarian reserve and for cancer patients with cryo-preserved ovaries. Generation of a large number of human oocytes also facilitates future derivation of embryonic stem cells for regenerative medicine.

  5. Sunspot proper motions in active region NOAA 2372 and its flare activity during SMY period of 1980 April 4-13

    International Nuclear Information System (INIS)

    Ambastha, A.; Bhatnagar, A.

    1988-01-01

    Solar Active Region NOAA 2372 was observed extensively by the Solar Maximum Mission (SMM) satellite and several ground-based observatories during 1980 April 4-13 in the Solar Maximum Year. After its birth around April 4, it underwent a rapid growth and produced a reported 84 flares in the course of its disc passage. In this paper, photospheric and chromospheric observations of this active region have been studied together with Marshall Space Flight Center magnetograms and X-ray data from HXIS aboard the SMM satellite. In particular, the relationship of the flare-productivity with sunspot proper motions and emergence of new regions of magnetic flux in the active region from its birth to its disappearance at the W-limb has been discussed. (author). 7 figures, 2 tables, 29 refs

  6. Factors affecting trip generation of motorcyclist for the purpose of non-mandatory activities

    Science.gov (United States)

    Anggraini, Renni; Sugiarto, Sugiarto; Pramanda, Heru

    2017-11-01

    The inadequate facilities and limited access to public transport reflect many people using private vehicles, in particular, motorcycle. The motorcycle is most widely used in Indonesia, recently, including Aceh Province. As a result, the number of motorcycle ownership is increasing significantly. The increasing number of motorcycles leads to complex traffic problems. Several factors tend to affect the trip generation of the motorcyclist, i.e., the social demographics of individuals and families, accessibility, etc. This study aims to analyze the characteristics of motorcyclists for non-mandatory activities, i.e. activities other than to work and school. It also aims to determine the dominant factors that affect their trips through trip generation models. The required data consist of primary data and secondary data. Primary data consists of a home interview survey that collects individual's daily trips. It is conducted by distributing the questionnaires to 400 families residing in Lhokseumawe City. Modeling the trip generation of the motorcyclist is done by multiple linear regression analysis. Parameters calibration uses OLS (Ordinary Least Square) method. The results showed that the dominant variables that affect the trip generation of motorcyclist for non-mandatory activities are license ownership, housewife, school-age children, middle-income household, and lower education level. It can be concluded that some factors affecting trip generation to non-work activities were female motorcyclists from the middle-income household with lower education level. As their status is mostly as the housewife, escorting children to non-school activities seems to the mother's task, instead of the father. It is clear that, most female ride motorcycle for doing household tasks. However, it should be noted that the use of the motorcycle in long-term does not suit for sustainable transportation.

  7. Forestry: Prospective Scenarios for Generating Eletricity

    Directory of Open Access Journals (Sweden)

    Henrique Dias Blois

    2017-05-01

    Full Text Available Forestry generates in all production segments a lot of waste which is a potential power source and an opportunity for electricity generation by the use of this material. Therefore, this study represents the construction of future scenarios for the power generation sector from alternative and renewable sources in the region of Vale do Taquari and Alto da Serra do Botucaraí, in the Northern-Central region of the Stat of Rio Grande do Sul, aiming for the application of waste and by-products from forestry present in a intensive and tendentious way in economic activities within the region. By way of prospective scenarios, one will be able to observe which events are impactful on the viability of an environmental project for recovery of forestry waste to generate electricity in the region. Thereby, we used the method described by Grumbach (2000, a methodology that prospects scenarios from the participation of experts, who collaborated analyzing and proposing events that impact as strengths and weaknesses, opportunities and threats and their interrelationships. Also, it was evident the degree of influence and dependence between the events, which create a matrix of cross impacts. Moreover, possible future scenarios have been constructed and analyzed for demonstrating that the study area has potential events that could serve as alternatives to the sector. However, no ideal scenario has been identified for the next five years, a fact that is due to the large amount of adverse events in six out of the ten final events.

  8. A study of lightning activity over land and oceanic regions of India

    Indian Academy of Sciences (India)

    important point and above results have strongly motivated us to take up the study of land–land and land–ocean contrast in lightning activity over. India. The geographic regions of India chosen for the present study include: • Eastern region (ER) and western region (WR) of India,. • East coast of India and a strip of six oceanic.

  9. Evaluation of the functional activity of activated sludge from local waste water treatment plant in the Arctic region

    Directory of Open Access Journals (Sweden)

    Il'inskiy V. V.

    2017-03-01

    Full Text Available The paper considers characteristics of the activated sludge in the local wastewater treatment plant (LWTP and its ability to purify fully domestic sewage water in the Far North. Biochemical process of destruction of organic pollutants is influenced by a microbial complex functioning in aeration tanks. Taking into account climatic conditions of the region where the organic matter degradation processes are slowed, and lack of control over the operation, efficiency and occupational safety of LWTPs, it seems to be important to study the physiological characteristics of the bacteria used in bioremediation, and their ability to maximize the purifying domestic sewage in the Arctic region. Undue intervention in the biosphere systems leads to disruption of the balance of internal and external ecosystems communications. The goal of research is studying structural determination and functioning of activated sludge bacteriocenosis of LWTP TOPAS-5 (GK "Topol-ECO" in certain physical and chemical conditions of the habitat, and establishing completeness of cleaning process in this treatment plant. The paper considers the structure (quantitative and qualitative composition and function of LWTP activated sludge bacteriocenosis functioning in the Arctic region. The estimation of the activated sludge of full waste water treatment process of the LWTP has been given. The research's results have allowed to identify and determine the bacterial count of physiological groups of microorganisms purified domestic sewage; to isolate from activated sludge the bioflocculant-producing microorganisms' on the experimental medium; to evaluate efficiency of LWTP work in the Arctic region

  10. Numerical study of three-dimensional natural convection and entropy generation in a cubical cavity with partially active vertical walls

    Directory of Open Access Journals (Sweden)

    Abdullah A.A.A Al-Rashed

    2017-09-01

    Full Text Available Natural convection and entropy generation due to the heat transfer and fluid friction irreversibilities in a three-dimensional cubical cavity with partially heated and cooled vertical walls has been investigated numerically using the finite volume method. Four different arrangements of partially active vertical sidewalls of the cubical cavity are considered. Numerical calculations are carried out for Rayleigh numbers from (103 ≤ Ra ≤ 106, various locations of the partial heating and cooling vertical sidewalls, while the Prandtl number of air is considered constant as Pr=0.7 and the irreversibility coefficient is taken as (φ=10−4. The results explain that the total entropy generation rate increases when the Rayleigh number increases. While, the Bejan number decreases as the Rayleigh number increases. Also, it is found that the arrangements of heating and cooling regions have a significant effect on the fluid flow and heat transfer characteristics of natural convection and entropy generation in a cubical cavity. The Middle-Middle arrangement produces higher values of average Nusselt numbers.

  11. Functional connections between activated and deactivated brain regions mediate emotional interference during externally directed cognition.

    Science.gov (United States)

    Di Plinio, Simone; Ferri, Francesca; Marzetti, Laura; Romani, Gian Luca; Northoff, Georg; Pizzella, Vittorio

    2018-04-24

    Recent evidence shows that task-deactivations are functionally relevant for cognitive performance. Indeed, higher cognitive engagement has been associated with higher suppression of activity in task-deactivated brain regions - usually ascribed to the Default Mode Network (DMN). Moreover, a negative correlation between these regions and areas actively engaged by the task is associated with better performance. DMN regions show positive modulation during autobiographical, social, and emotional tasks. However, it is not clear how processing of emotional stimuli affects the interplay between the DMN and executive brain regions. We studied this interplay in an fMRI experiment using emotional negative stimuli as distractors. Activity modulations induced by the emotional interference of negative stimuli were found in frontal, parietal, and visual areas, and were associated with modulations of functional connectivity between these task-activated areas and DMN regions. A worse performance was predicted both by lower activity in the superior parietal cortex and higher connectivity between visual areas and frontal DMN regions. Connectivity between right inferior frontal gyrus and several DMN regions in the left hemisphere was related to the behavioral performance. This relation was weaker in the negative than in the neutral condition, likely suggesting less functional inhibitions of DMN regions during emotional processing. These results show that both executive and DMN regions are crucial for the emotional interference process and suggest that DMN connections are related to the interplay between externally-directed and internally-focused processes. Among DMN regions, superior frontal gyrus may be a key node in regulating the interference triggered by emotional stimuli. © 2018 Wiley Periodicals, Inc.

  12. Estimates of power generated from synchrotron radiation in the HL-LHC experimental insertion regions

    CERN Document Server

    Rossi, Adriana; CERN. Geneva. ATS Department

    2017-01-01

    The power generated in single magnets of the HL-LHC experimental regions is estimated for collision optics HLLHCV1.2 β*=15 cm Round and HLLHCV1.2 Flat. Note that the layout used for the computations presented here is that before the recent change of baseline. These values should serve as input to Monte-Carlo codes (i.e., PHOTON [ ], Synrad [ ] or others), able to calculate the heat load distribution along the machine and in particular the Long Straight Sections (LSS).

  13. Evolution of active region loop plasma

    International Nuclear Information System (INIS)

    Krall, K.R.; Antiochos, S.K.

    1980-01-01

    We investigate numerically the adjustment of coronal active-region loops to changes in their heating rate. The one-dimensional hydrodynamic equations are solved subject to boundary conditions in which heat flux-induced mass exchange between coronal and chromospheric components is allowed. The calculated evolution of physical parameters suggests that (1) mass supplied during chromospheric evaporation is much more effective in moderating coronal temperature excursions than when downward heat flux if dissipated by a static chromosphere, and (2) the method by which rhe chromosphere responds to changing coronal conditions can significantly influence coronal readjustment time scales. Observations are cited which illustrate the range of possible fluctuations in the heating rates

  14. Changes in X-ray brightness of a solar active region

    Energy Technology Data Exchange (ETDEWEB)

    Glencross, W M; Brabban, D H [University Coll., London (UK). Mullard Space Science Lab.

    1976-04-01

    The soft X-ray flux in the waveband 0.3 to 0.9 nm has been monitored during most of the solar disk passage of McMath region 12094. These data show how the emission changed during quiet periods as well as during flaring. Throughout the first four days of observations the mean flux showed a gradual decay even though the magnetic region was still growing. At the end of this phase the region remained extremely inactive for almost half a day and then brightened by more than an order of magnitude within an hour. This enhancement lasted nearly one day and marked the onset of the break-up of the region. It is shown how this sequence of events might reflect the changes in subphotospheric convection pattern which Meyer et al (Mon. Not. R. Astr. Soc.; 169:35 (1974)) consider to develop in magnetic regions. It is also pointed out that the large flares in region 11976 during early 1972 August had a number of characteristics in common with the active phase discussed for region 12094.

  15. Macroeconomic dataset for generating macroeconomic volatility among selected countries in the Asia Pacific region

    Directory of Open Access Journals (Sweden)

    Yee Peng Chow

    2018-02-01

    Full Text Available This data article provides macroeconomic data that can be used to generate macroeconomic volatility. The data cover a sample of seven selected countries in the Asia Pacific region for the period 2004–2014, including both developing and developed countries. This dataset was generated to enhance our understanding of the sources of macroeconomic volatility affecting the countries in this region. Although the Asia Pacific region continues to remain as the most dynamic part of the world's economy, it is not spared from various sources of macroeconomic volatility through the decades. The reported data cover 15 types of macroeconomic data series, representing three broad categories of indicators that can be used to proxy macroeconomic volatility. They are indicators that account for macroeconomic volatility (i.e. volatility as a macroeconomic outcome, domestic sources of macroeconomic volatility and external sources of macroeconomic volatility. In particular, the selected countries are Malaysia, Thailand, Indonesia and Philippines, which are regarded as developing countries, while Singapore, Japan and Australia are developed countries. Despite the differences in level of economic development, these countries were affected by similar sources of macroeconomic volatility such as the Asian Financial Crisis and the Global Financial Crisis. These countries were also affected by other similar external turbulence arising from factors such as the global economic slowdown, geopolitical risks in the Middle East and volatile commodity prices. Nonetheless, there were also sources of macroeconomic volatility which were peculiar to certain countries only. These were generally domestic sources of volatility such as political instability (for Thailand, Indonesia and Philippines, natural disasters and anomalous weather conditions (for Thailand, Indonesia, Philippines, Japan and Australia and over-dependence on the electronic sector (for Singapore. Keywords

  16. Ministerial comments on the regional perspective workshops

    International Nuclear Information System (INIS)

    Sihota, M.

    1993-01-01

    The role of British Columbia Hydro in addressing regional economic development issues in British Columbia is discussed. At Stave Falls in the Fraser Valley, a project is under way to upgrade a 75-year-old hydroelectric facility to utilize its potential more fully without having to flood more land. The project will eventually cost $50-100 million and will also generate local employment. In the Kootenay region, the utility has established a regional office in Castlegar and is organizing a symposium to examine historical grievances such as reservoir levels, taxation, and electric system operation. A new formula has been announced with regards to independent power producers and it is intended to proceed with wood-waste power generation and gas-fired cogeneration projects if they make economic and environmental sense. Energy conservation activities are continually being implemented through the utility's Power Smart program, and tourism-related concerns caused by low reservoir levels in the Kootenay region are also being addressed

  17. Improvement of Measurement and Evaluation of Regional Authorities Activity: Model and Statistical Approach

    Directory of Open Access Journals (Sweden)

    Petrova Elena Аleksandrovna

    2014-11-01

    Full Text Available Formation of strategy of long-term social and economic development is a basis for effective functioning of executive authorities and the assessment of its efficiency in general. Modern theories of assessment of public administration productivity are guided by the process approach when it is expedient to carry out the formation of business processes of regional executive authorities according to strategic indicators of territorial development. In this regard, there is a problem of modeling of interrelation of indicators of social and economic development of the region and quantitative indices of results of business processes of executive authorities. At the first stage of modeling, two main directions of strategic development, namely innovative and investment activity of regional economic systems are considered. In this regard, the work presents the results of modeling the interrelation between the indicators of regional social and economic development and innovative and investment activity. Therefore, for carrying out the analysis, the social and economic system of the region is presented in space of the main indicators of social and economic development of the territory and indicators of innovative and investment activity. The analysis is made on values of the indicators calculated for regions of the Russian Federation during 2000, 2005, 2008, 2010 and 2011. It was revealed that strategic indicators of innovative and investment activity have the most significant impact on key signs of social and economic development.

  18. Solar and Stellar Active Regions:Cosmic laboratories for the study of Complexity

    OpenAIRE

    Vlahos, Loukas

    2008-01-01

    Solar active regions are driven dissipative dynamical systems. The turbulent convection zone forces new magnetic flux tubes to rise above the photosphere and shuffles the magnetic fields which are already above the photosphere. The driven 3D active region responds to the driver with the formation of Thin Current Sheets in all scales and releases impulsively energy, when special thresholds are met, on the form of nano-, micro-, flares and large scale coronal mass ejections. It has been documen...

  19. Centro Regional de Ciencias Nucleares (a Brazilian regional center for nuclear sciences) - activities report - 1999

    International Nuclear Information System (INIS)

    1999-12-01

    The annual activities report of 1999 of nuclear sciences regional center - Brazilian organization - introduces the next main topics: institutional relations; sectorial actions - logistic support and training, laboratory of radiation protection and dosimetry, laboratory of metrology, laboratory of chemical characterization; technical and scientific events; and financial resources and perspectives for 2000

  20. ON THE STRENGTH OF THE HEMISPHERIC RULE AND THE ORIGIN OF ACTIVE-REGION HELICITY

    International Nuclear Information System (INIS)

    Wang, Y.-M.

    2013-01-01

    Vector magnetograph and morphological observations have shown that the solar magnetic field tends to have negative (positive) helicity in the northern (southern) hemisphere, although only ∼60%-70% of active regions appear to obey this 'hemispheric rule'. In contrast, at least ∼80% of quiescent filaments and filament channels that form during the decay of active regions follow the rule. We attribute this discrepancy to the difficulty in determining the helicity sign of newly emerged active regions, which are dominated by their current-free component; as the transverse field is canceled at the polarity inversion lines, however, the axial component becomes dominant there, allowing a more reliable determination of the original active-region chirality. We thus deduce that the hemispheric rule is far stronger than generally assumed, and cannot be explained by stochastic processes. Earlier studies have shown that the twist associated with the axial tilt of active regions is too small to account for the observed helicity; here, both tilt and twist are induced by the Coriolis force acting on the diverging flow in the emerging flux tube. However, in addition to this east-west expansion about the apex of the loop, each of its legs must expand continually in cross section during its rise through the convection zone, thereby acquiring a further twist through the Coriolis force. Since this transverse pressure effect is not limited by drag or tension forces, the final twist depends mainly on the rise time, and may be large enough to explain the observed active-region helicity

  1. Generation of spectral clusters in a mixture of noble and Raman-active gases.

    Science.gov (United States)

    Hosseini, Pooria; Abdolvand, Amir; St J Russell, Philip

    2016-12-01

    We report a novel scheme for the generation of dense clusters of Raman sidebands. The scheme uses a broadband-guiding hollow-core photonic crystal fiber (HC-PCF) filled with a mixture of H2, D2, and Xe for efficient interaction between the gas mixture and a green laser pump pulse (532 nm, 1 ns) of only 5 μJ of energy. This results in the generation from noise of more than 135 rovibrational Raman sidebands covering the visible spectral region with an average spacing of only 2.2 THz. Such a spectrally dense and compact fiber-based source is ideal for applications where closely spaced narrow-band laser lines with high spectral power density are required, such as in spectroscopy and sensing. When the HC-PCF is filled with a H2-D2 mixture, the Raman comb spans the spectral region from the deep UV (280 nm) to the near infrared (1000 nm).

  2. Income Generation Activities among Academic Staffs at Malaysian Public Universities

    Science.gov (United States)

    Ahmad, Abd Rahman; Soon, Ng Kim; Ting, Ngeoh Pei

    2015-01-01

    Income generation activities have been acquainted among public higher education institutions (HEIs) in Malaysia. Various factors that brought to insufficient of funding caused Higher Education Institutions(HEIs) to seek for additional income as to support the operation expenses. Financial sustainability issues made up the significant impact…

  3. MAGNETIC FLUX TRANSPORT AND THE LONG-TERM EVOLUTION OF SOLAR ACTIVE REGIONS

    International Nuclear Information System (INIS)

    Ugarte-Urra, Ignacio; Upton, Lisa; Warren, Harry P.; Hathaway, David H.

    2015-01-01

    With multiple vantage points around the Sun, Solar Terrestrial Relations Observatory (STEREO) and Solar Dynamics Observatory imaging observations provide a unique opportunity to view the solar surface continuously. We use He ii 304 Å data from these observatories to isolate and track ten active regions and study their long-term evolution. We find that active regions typically follow a standard pattern of emergence over several days followed by a slower decay that is proportional in time to the peak intensity in the region. Since STEREO does not make direct observations of the magnetic field, we employ a flux-luminosity relationship to infer the total unsigned magnetic flux evolution. To investigate this magnetic flux decay over several rotations we use a surface flux transport model, the Advective Flux Transport model, that simulates convective flows using a time-varying velocity field and find that the model provides realistic predictions when information about the active region's magnetic field strength and distribution at peak flux is available. Finally, we illustrate how 304 Å images can be used as a proxy for magnetic flux measurements when magnetic field data is not accessible

  4. Energy policy strategies of the Baltic Sea Region for the post-Kyoto period - focusing on electricity and district heating generation

    Energy Technology Data Exchange (ETDEWEB)

    2012-05-15

    This study presents a comprehensive analysis of energy policy strategies for the Baltic Sea Region for the post-Kyoto period. To this aim, the study provides scenarios for the region in order to develop a both secure and climate-compatible energy system for the year 2020 and beyond. The long-term development of the energy systems in the Baltic Sea Region is analysed, i.e. in Denmark, Estonia, Finland, Germany, Latvia, Lithuania, Norway, Poland, Sweden, and the north western part of Russia. The study focuses on the electricity and district heating sectors. The Baltic Sea Region is comprised of countries with very different economies and characteristics. Hydropower is an important source of electricity generation in Norway, Sweden, Finland and Latvia. Biomass resources are significant throughout the region, deriving from both agricultural residues and large forested areas. Wind power already contributes considerably to electricity generation in countries such as Denmark and Germany, and is likely to play a much greater role in the region in the years to come, both onshore and offshore. In the longer term (2030 and beyond), solar power and geothermal energy could also provide notable contributions to the overall energy supply. The study shows that it is technically possible to reduce greenhouse gas emissions in the electricity and district heating sectors of the Baltic Sea Region by close to 100% using mainly renewable energy sources. The results indicate that this is a challenging, but manageable task. The associated costs are moderate and can be further decreased through regional cooperation. Once the various production technologies have the possibility to interact with district heating and flexible electricity consumption, and transmission connections are optimally utilised, it becomes realistic to integrate e.g. large volumes of wind power into the energy system as a whole. Furthermore, the hydro power reservoirs, particularly in Norway, play a key role in

  5. Integrated regional development of the Baltic region towards the sustainability of its ecosystem; A platform for thinking

    Energy Technology Data Exchange (ETDEWEB)

    Straszak, A; Owsinski, J W [Systems Research Institute, Polish Academy of Sciences, Warsaw (PL); Kairiukstis, L [Lithuanian Forest Research Institute, Kaunas, Lithuanian SSR (SU)

    1989-01-01

    The paper presents a systemic framework for the assessment of the current state and future development of the Baltic ecosystem as an integral part of a broader Baltic region system involving social, economic and ecological aspects. The paper formulates and adresses the following questions: with respect to what aspects is this region a system How do various systemicity reaches overlap How can be systemic behaviour rectified and /or improved, special attention being paid to inter-system synergy The focus is on the resource and ecological system of Baltic, as the potentially generative one for the other systemic structures. It is shown, though, that these other structures are not adequate to the generative one, and that this inadequacy impinges on both the economic and ecological performance. Thus, it is proposed that economic and social activities within the Baltic region should match better the variety of its resource and ecological substratum, thereby allowing smoother and more rapid development of the region and presservation of the sustainability of this devleopment. Examples range from economic cooperation and transport to tourism and recreation, and nature protection. (author).

  6. Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins

    DEFF Research Database (Denmark)

    Thiel, Steffen

    2007-01-01

    Mannan-binding lectin (MBL), L-ficolin, M-ficolin and H-ficolin are all complement activating soluble pattern recognition molecules with recognition domains linked to collagen-like regions. All four may form complexes with four structurally related proteins, the three MBL-associated serine...... proteases (MASPs), MASP-1, MASP-2 and MASP-3, and a smaller MBL-associated protein (MAp19). The four recognition molecules recognize patterns of carbohydrate or acetyl-group containing ligands. After binding to the relevant targets all four are able to activate the complement system. We thus have a system...... where four different and/or overlapping patterns of microbial origin or patterns of altered-self may be recognized, but in all cases the signalling molecules, the MASPs, are shared. MASP-1 and MASP-3 are formed from one gene, MASP1/3, by alternative splicing generating two different mRNAs from a single...

  7. The Influence Of Highway Transportation Infrastructure Condition Toward Commodity Production Generation for The Resilience Needs at Regional Internal Zone

    Science.gov (United States)

    Akbardin, Juang; Parikesit, Danang; Riyanto, Bambang; Mulyono, Agus Taufik

    2018-02-01

    The poultry commodity consumption and requirement is one of the main commodities that must be fulfilled in a region to maintain the availability of meat from poultry. Poultry commodity production is one of the production sectors that have a clean environment resistance. An increasing of poultry commodity generation production requires a smooth distribution to arrive at the processing. The livestock location as a commodity production is placed at a considerable far distance from residential and market locations. Zones that have poultry commodity production have an excess potential to supply other zones that are lacking in production to the consumption of these commodities. The condition of highway transportation infrastructure that is very diverse with the damage level availability in a zone has an influence in the supply and demand of poultry commodity requirement in the regional internal of Central Java province. In order to know the effect of highway transportation infrastructure condition toward the poultry commodity movement, demography factor and availability of freight vehicles will be reviewed to estimate the amount of poultry commodity movement generation production. Thus the poultry commodity consumption requirement that located in the internal - regional zone of central java province can be adequated from the zone. So it can be minimized the negative impacts that affect the environment at the zone in terms of comparison of the movement attraction and generation production at poultry commodity in Central Java.

  8. Determinants of anti-corruption activities at the regional level

    Directory of Open Access Journals (Sweden)

    T. I. Ovchinnikova

    2018-01-01

    Full Text Available The article explores the concept of corruption, defined as an obstacle to economic and social development, created by representatives of the power structures of the country, region, enterprise, weakening the efficiency of management and the institutional foundation of society. Anticorruption activity is presented in the article as conditions created by the state and ensuring that the country's economy is not irreparably damaged by internal and external economic threats. The estimated characteristics of the anti-corruption activities of the regions and the country as a whole, as a rule, are studied in the domestic sources and among foreign authors. Statistical evaluation of the relationship between the level of corruption and indicators: the dynamics of GRP growth, the index of real incomes of the population, the costs of training, health care is made on the basis of the coefficient Pearson correlation. Based on the correlation analysis, stable links were established between the level of corruption and the socio-economic indicators of the region's development: an increase in the level of corruption associated with an increase in the population's spending on education and medicine; a reduction in the level of corruption, as a result of increased incomes of the population and higher wages. The consequences of corruption are presented: legal (the undeveloped legislative base, which involves bribery of powerful people, the growth of corruption in the society, the increase in corruption crimes, the inefficiency of the regulatory framework, social (moral violation, low public evaluation of the activities of power structures, low level of culture and upbringing , economic (bias financial, investment decisions, illegal distribution of property and non-property benefits, the impossibility of competitors Vat with developed countries and others.

  9. Altered regional homogeneity of spontaneous brain activity in idiopathic trigeminal neuralgia.

    Science.gov (United States)

    Wang, Yanping; Zhang, Xiaoling; Guan, Qiaobing; Wan, Lihong; Yi, Yahui; Liu, Chun-Feng

    2015-01-01

    The pathophysiology of idiopathic trigeminal neuralgia (ITN) has conventionally been thought to be induced by neurovascular compression theory. Recent structural brain imaging evidence has suggested an additional central component for ITN pathophysiology. However, far less attention has been given to investigations of the basis of abnormal resting-state brain activity in these patients. The objective of this study was to investigate local brain activity in patients with ITN and its correlation with clinical variables of pain. Resting-state functional magnetic resonance imaging data from 17 patients with ITN and 19 age- and sex-matched healthy controls were analyzed using regional homogeneity (ReHo) analysis, which is a data-driven approach used to measure the regional synchronization of spontaneous brain activity. Patients with ITN had decreased ReHo in the left amygdala, right parahippocampal gyrus, and left cerebellum and increased ReHo in the right inferior temporal gyrus, right thalamus, right inferior parietal lobule, and left postcentral gyrus (corrected). Furthermore, the increase in ReHo in the left precentral gyrus was positively correlated with visual analog scale (r=0.54; P=0.002). Our study found abnormal functional homogeneity of intrinsic brain activity in several regions in ITN, suggesting the maladaptivity of the process of daily pain attacks and a central role for the pathophysiology of ITN.

  10. Formation of a double-decker magnetic flux rope in the sigmoidal solar active region 11520

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, X.; Ding, M. D.; Zhang, J.; Guo, Y. [School of Astronomy and Space Science, Nanjing University, Nanjing 210093 (China); Sun, X. D. [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305 (United States); Wang, Y. M. [School of Earth and Space Sciences, University of Science and Technology of China, Hefei 230026 (China); Kliem, B. [Institute of Physics and Astronomy, University of Potsdam, D-14476 Potsdam (Germany); Deng, Y. Y., E-mail: xincheng@nju.edu.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2014-07-10

    In this paper, we address the formation of a magnetic flux rope (MFR) that erupted on 2012 July 12 and caused a strong geomagnetic storm event on July 15. Through analyzing the long-term evolution of the associated active region observed by the Atmospheric Imaging Assembly and the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory, it is found that the twisted field of an MFR, indicated by a continuous S-shaped sigmoid, is built up from two groups of sheared arcades near the main polarity inversion line a half day before the eruption. The temperature within the twisted field and sheared arcades is higher than that of the ambient volume, suggesting that magnetic reconnection most likely works there. The driver behind the reconnection is attributed to shearing and converging motions at magnetic footpoints with velocities in the range of 0.1-0.6 km s{sup –1}. The rotation of the preceding sunspot also contributes to the MFR buildup. Extrapolated three-dimensional non-linear force-free field structures further reveal the locations of the reconnection to be in a bald-patch region and in a hyperbolic flux tube. About 2 hr before the eruption, indications of a second MFR in the form of an S-shaped hot channel are seen. It lies above the original MFR that continuously exists and includes a filament. The whole structure thus makes up a stable double-decker MFR system for hours prior to the eruption. Eventually, after entering the domain of instability, the high-lying MFR impulsively erupts to generate a fast coronal mass ejection and X-class flare; while the low-lying MFR remains behind and continuously maintains the sigmoidicity of the active region.

  11. Formation of a double-decker magnetic flux rope in the sigmoidal solar active region 11520

    International Nuclear Information System (INIS)

    Cheng, X.; Ding, M. D.; Zhang, J.; Guo, Y.; Sun, X. D.; Wang, Y. M.; Kliem, B.; Deng, Y. Y.

    2014-01-01

    In this paper, we address the formation of a magnetic flux rope (MFR) that erupted on 2012 July 12 and caused a strong geomagnetic storm event on July 15. Through analyzing the long-term evolution of the associated active region observed by the Atmospheric Imaging Assembly and the Helioseismic and Magnetic Imager on board the Solar Dynamics Observatory, it is found that the twisted field of an MFR, indicated by a continuous S-shaped sigmoid, is built up from two groups of sheared arcades near the main polarity inversion line a half day before the eruption. The temperature within the twisted field and sheared arcades is higher than that of the ambient volume, suggesting that magnetic reconnection most likely works there. The driver behind the reconnection is attributed to shearing and converging motions at magnetic footpoints with velocities in the range of 0.1-0.6 km s –1 . The rotation of the preceding sunspot also contributes to the MFR buildup. Extrapolated three-dimensional non-linear force-free field structures further reveal the locations of the reconnection to be in a bald-patch region and in a hyperbolic flux tube. About 2 hr before the eruption, indications of a second MFR in the form of an S-shaped hot channel are seen. It lies above the original MFR that continuously exists and includes a filament. The whole structure thus makes up a stable double-decker MFR system for hours prior to the eruption. Eventually, after entering the domain of instability, the high-lying MFR impulsively erupts to generate a fast coronal mass ejection and X-class flare; while the low-lying MFR remains behind and continuously maintains the sigmoidicity of the active region.

  12. Micrurus snake venoms activate human complement system and generate anaphylatoxins

    Directory of Open Access Journals (Sweden)

    Tanaka Gabriela D

    2012-01-01

    Full Text Available Abstract Background The genus Micrurus, coral snakes (Serpentes, Elapidae, comprises more than 120 species and subspecies distributed from the south United States to the south of South America. Micrurus snake bites can cause death by muscle paralysis and further respiratory arrest within a few hours after envenomation. Clinical observations show mainly neurotoxic symptoms, although other biological activities have also been experimentally observed, including cardiotoxicity, hemolysis, edema and myotoxicity. Results In the present study we have investigated the action of venoms from seven species of snakes from the genus Micrurus on the complement system in in vitro studies. Several of the Micrurus species could consume the classical and/or the lectin pathways, but not the alternative pathway, and C3a, C4a and C5a were generated in sera treated with the venoms as result of this complement activation. Micrurus venoms were also able to directly cleave the α chain of the component C3, but not of the C4, which was inhibited by 1,10 Phenanthroline, suggesting the presence of a C3α chain specific metalloprotease in Micrurus spp venoms. Furthermore, complement activation was in part associated with the cleavage of C1-Inhibitor by protease(s present in the venoms, which disrupts complement activation control. Conclusion Micrurus venoms can activate the complement system, generating a significant amount of anaphylatoxins, which may assist due to their vasodilatory effects, to enhance the spreading of other venom components during the envenomation process.

  13. Mid-infrared supercontinuum generation in the fingerprint region

    DEFF Research Database (Denmark)

    Møller, Uffe Visbech; Petersen, Christian Rosenberg; Kubat, Irnis

    The mid-infrared spectral region is of great technical and scientific interest because most molecules display fundamental vibrational absorptions in this region, leaving distinctive spectral fingerprints. Here, we demonstrate experimentally that launching intense ultra-short pulses with a central...... the potential of fibres to emit across the mid-infrared molecular fingerprint region, which is of key importance for applications such as early cancer diagnostics, gas sensing and food quality control....

  14. Optimal mix of renewable power generation in the MENA region as a basis for an efficient electricity supply to europe

    Science.gov (United States)

    Alhamwi, Alaa; Kleinhans, David; Weitemeyer, Stefan; Vogt, Thomas

    2014-12-01

    Renewable Energy sources are gaining importance in the Middle East and North Africa (MENA) region. The purpose of this study is to quantify the optimal mix of renewable power generation in the MENA region, taking Morocco as a case study. Based on hourly meteorological data and load data, a 100% solar-plus-wind only scenario for Morocco is investigated. For the optimal mix analyses, a mismatch energy modelling approach is adopted with the objective to minimise the required storage capacities. For a hypothetical Moroccan energy supply system which is entirely based on renewable energy sources, our results show that the minimum storage capacity is achieved at a share of 63% solar and 37% wind power generations.

  15. Coaxial Mono-Energetic Gamma Generator for Active Interrogation

    International Nuclear Information System (INIS)

    Ludewigt, Bernhard A.; Antolak, A.J.; Henestroza, E.; Leitner, M.; Leung, K.-N.; Waldron, W.; Wilde, S.; Kwan, J.W.

    2008-01-01

    Compact mono-energetic photon sources are sought for active interrogation systems to detect shielded special nuclear materials in, for example, cargo containers, trucks and other vehicles. A prototype gamma interrogation source has been designed and built that utilizes the 11B(p,gamma)12C reaction to produce 12 MeV gamma-rays which are near the peak of the photofission cross section. In particular, the 11B(p,gamma)12C resonance at 163 kV allows the production of gammas at low proton acceleration voltages, thus keeping the design of a gamma generator comparatively small and simple. A coaxial design has been adopted with a toroidal-shaped plasma chamber surrounding a cylindrical gamma production target. The plasma discharge is driven by a 2 MHz rf-power supply (capable up to 50 kW) using a circular rf-antenna. Permanent magnets embedded in the walls of the plasma chamber generate a multi-cusp field that confines the plasma and allows higher plasma densities and lower gas pressures. About 100 proton beamlets are extracted through a slotted plasma electrode towards the target at the center of the device that is at a negative 180 kV. The target consists of LaB6 tiles that are brazed to a water-cooled cylindrical structure. The generator is designed to operate at 500 Hz with 20 mu s long pulses, and a 1percent duty factor by pulsing the ion source rf-power. A first-generation coaxial gamma source has been built for low duty factor experiments and testing.

  16. The Solomon Sea eddy activity from a 1/36° regional model

    Science.gov (United States)

    Djath, Bughsin; Babonneix, Antoine; Gourdeau, Lionel; Marin, Frédéric; Verron, Jacques

    2013-04-01

    In the South West Pacific, the Solomon Sea exhibits the highest levels of eddy kinetic energy but relatively little is known about the eddy activity in this region. This Sea is directly influenced by a monsoonal regime and ENSO variability, and occupies a strategical location as the Western Boundary Currents exiting it are known to feed the warm pool and to be the principal sources of the Equatorial UnderCurrent. During their transit in the Solomon Sea, meso-scale eddies are suspected to notably interact and influence these water masses. The goal of this study is to give an exhaustive description of this eddy activity. A dual approach, based both on altimetric data and high resolution modeling, has then been chosen for this purpose. First, an algorithm is applied on nearly 20 years of 1/3° x 1/3° gridded SLA maps (provided by the AVISO project). This allows eddies to be automatically detected and tracked, thus providing some basic eddy properties. The preliminary results show that two main and distinct types of eddies are detected. Eddies in the north-eastern part shows a variability associated with the mean structure, while those in the southern part are associated with generation/propagation processes. However, the resolution of the AVISO dataset is not very well suited to observe fine structures and to match with the numerous islands bordering the Solomon Sea. For this reason, we will confront these observations with the outputs of a 1/36° resolution realistic model of the Solomon Sea. The high resolution numerical model (1/36°) indeed permits to reproduce very fine scale features, such as eddies and filaments. The model is two-way embedded in a 1/12° regional model which is itself one-way embedded in the DRAKKAR 1/12° global model. The NEMO code is used as well as the AGRIF software for model nestings. Validation is realized by comparison with AVISO observations and available in situ data. In preparing the future wide-swath altimetric SWOT mission that is

  17. Effects of climate change on income generating activities of farmers ...

    African Journals Online (AJOL)

    The need to examine the changes that the effect of climate change brings about on the income generating activities of farmers necessitated this study. Two local government areas (LGAs) were randomly selected and simple random sampling was used to sample 160 farmers from the 2 LGAs. Chi-square and Pearson ...

  18. Time-Elastic Generative Model for Acceleration Time Series in Human Activity Recognition.

    Science.gov (United States)

    Munoz-Organero, Mario; Ruiz-Blazquez, Ramona

    2017-02-08

    Body-worn sensors in general and accelerometers in particular have been widely used in order to detect human movements and activities. The execution of each type of movement by each particular individual generates sequences of time series of sensed data from which specific movement related patterns can be assessed. Several machine learning algorithms have been used over windowed segments of sensed data in order to detect such patterns in activity recognition based on intermediate features (either hand-crafted or automatically learned from data). The underlying assumption is that the computed features will capture statistical differences that can properly classify different movements and activities after a training phase based on sensed data. In order to achieve high accuracy and recall rates (and guarantee the generalization of the system to new users), the training data have to contain enough information to characterize all possible ways of executing the activity or movement to be detected. This could imply large amounts of data and a complex and time-consuming training phase, which has been shown to be even more relevant when automatically learning the optimal features to be used. In this paper, we present a novel generative model that is able to generate sequences of time series for characterizing a particular movement based on the time elasticity properties of the sensed data. The model is used to train a stack of auto-encoders in order to learn the particular features able to detect human movements. The results of movement detection using a newly generated database with information on five users performing six different movements are presented. The generalization of results using an existing database is also presented in the paper. The results show that the proposed mechanism is able to obtain acceptable recognition rates ( F = 0.77) even in the case of using different people executing a different sequence of movements and using different hardware.

  19. Signatures of Slow Solar Wind Streams from Active Regions in the Inner Corona

    Science.gov (United States)

    Slemzin, V.; Harra, L.; Urnov, A.; Kuzin, S.; Goryaev, F.; Berghmans, D.

    2013-08-01

    The identification of solar-wind sources is an important question in solar physics. The existing solar-wind models ( e.g., the Wang-Sheeley-Arge model) provide the approximate locations of the solar wind sources based on magnetic field extrapolations. It has been suggested recently that plasma outflows observed at the edges of active regions may be a source of the slow solar wind. To explore this we analyze an isolated active region (AR) adjacent to small coronal hole (CH) in July/August 2009. On 1 August, Hinode/EUV Imaging Spectrometer observations showed two compact outflow regions in the corona. Coronal rays were observed above the active-region coronal hole (ARCH) region on the eastern limb on 31 July by STEREO-A/EUVI and at the western limb on 7 August by CORONAS- Photon/TESIS telescopes. In both cases the coronal rays were co-aligned with open magnetic-field lines given by the potential field source surface model, which expanded into the streamer. The solar-wind parameters measured by STEREO-B, ACE, Wind, and STEREO-A confirmed the identification of the ARCH as a source region of the slow solar wind. The results of the study support the suggestion that coronal rays can represent signatures of outflows from ARs propagating in the inner corona along open field lines into the heliosphere.

  20. ECONOMIC COMPARATIVE EVALUATION OF COMBINATION OF ACTIVATED CARBON GENERATION AND SPENT ACTIVATED CARBON REGENERATION PLANTS

    Directory of Open Access Journals (Sweden)

    TINNABHOP SANTADKHA

    2017-12-01

    Full Text Available The purpose of this study was to investigate the maximum annual profit of proposed three project plants as follows: (i a generation process of activated carbon (AC prepared from coconut shells; (ii a regeneration process of spent AC obtained from petrochemical industries; and (iii a project combined the AC generation process with the regeneration process. The maximum annual profit obtained from the sole regeneration plant was about 1.2- and 15.4- fold higher than that obtained from the integrated and the generation plants, respectively. The sensitivity of selected variables to net present value (NPV, AC sales price was the most sensitive to NPV while fixed costs of generation and regeneration, and variable cost of regeneration were the least sensitive to NPV. Based on the optimal results of each project plant, the economic indicators namely NPV, return on investment (ROI, internal rate of return (IRR, and simple payback period (SPP were determined. Applying a rule of thumb of 12% IRR and 7-year SPP, the AC sales prices for the generation, regeneration, and integrated plants were 674.31, 514.66 and 536.66 USD/ton of product, respectively. The economic analysis suggested that the sole regeneration project yields more profitable.

  1. Active Learning Innovations in Knowledge Management Education Generate Higher Quality Learning Outcomes

    Directory of Open Access Journals (Sweden)

    Arthur Shelley

    2014-01-01

    Full Text Available Innovations in how a postgraduate course in knowledge management is delivered have generated better learning outcomes and made the course more engaging for learners. Course participant feedback has shown that collaborative active learning is preferred and provides them with richer insights into how knowledge is created and applied to generate innovation and value. The course applies an andragogy approach in which students collaborate in weekly dialogue of their experiences of the content, rather than learn the content itself. The approach combines systems thinking, learning praxis, and active learning to explore the interdependencies between topics and how they impact outcomes in real world situations. This has stimulated students to apply these ideas in their own workplaces.

  2. Electric-current Neutralization, Magnetic Shear, and Eruptive Activity in Solar Active Regions

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yang; Sun, Xudong [W. W. Hansen Experimental Physics Laboratory, Stanford University, Stanford, CA 94305-4085 (United States); Török, Tibor; Titov, Viacheslav S. [Predictive Science Inc., 9990 Mesa Rim Road, Suite 170, San Diego, CA 92121 (United States); Leake, James E. [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States)

    2017-09-01

    The physical conditions that determine whether or not solar active regions (ARs) produce strong flares and coronal mass ejections (CMEs) are not yet well understood. Here, we investigate the association between electric-current neutralization, magnetic shear along polarity inversion lines (PILs), and eruptive activity in four ARs: two emerging and two well-developed ones. We find that the CME-producing ARs are characterized by a strongly non-neutralized total current, while the total current in the ARs that did not produce CMEs is almost perfectly neutralized. The difference in the PIL shear between these two groups is much less pronounced, which suggests that the degree of current neutralization may serve as a better proxy for assessing the ability of ARs to produce CMEs.

  3. Does FDI promote regional development? Evidence from local and regional productivity spillovers in Greece

    Directory of Open Access Journals (Sweden)

    Vassilis MONASTIRIOTIS

    2010-12-01

    Full Text Available Studies on the productivity spillovers of FDI have concentrated on the nationalsectoral level. As a result, little is known about the impact of FDI on absolute and relative regional economic performance. In this paper we examine this issue by relying on a unique dataset of over 20,000 Greek firms for the period 2002-2006 covering all sectors of economic activity. We examine the spatial distribution of foreign-owned firms in the country and analyse the effect that their presence – at the local, regional and national levels – has on the productivity of domestic firms. We find strong evidence suggesting that foreignowned firms self-select into regions and sectors of high productivity. Net of this selection effect, the impact of foreign presence on domestic productivity is negative – although at the very local level some positive spillover effects are identifiable. The bulk of the effects concentrate in non-manufacturing activities, high-tech sectors, and medium-sized high-productivity firms. Importantly, this effect is not constant across space however. Productivity spillovers tend to be negative in the regions hosting the main urban areas in the country but positive in smaller and more peripheral regions. In this way, despite the tendency of FDI to concentrate in a limited number of areas within the country – those of the highest level of development – the externalities that FDI activity generates to the local economies appear to be of a rather equilibrating character.

  4. Blue-green ZnSe lasers with a new type of active region

    International Nuclear Information System (INIS)

    Ivanov, S.V.; Toropov, A.A.; Sorokin, S.V.; Shubina, T.V.; Sedova, I.V.; Kop'ev, P.S.; Alferov, Zh.I.; Waag, A.; Lugauer, H.J.; Reuscher, G.; Keim, M.; Fischer, F.F.; Landwehr, G.

    1999-01-01

    We report the results of an experimental study of molecular-beam epitaxy of ZnSe-based laser heterostructures with a new structure of the active region, which contains a fractional-monolayer CdSe recombination region in an expanded ZnSe quantum well and a waveguide based on a variably-strained, short-period superlattice are reported. Growth of a fractional-monolayer CdSe region with a nominal thickness of 2-3 ML, i.e., less than the critical thickness, on a ZnSe surface (Δa/a∼7%) leads to the formation of self-organized, pseudomorphic, CdSe-enriched islands with lateral dimensions ∼10-30 nm and density ∼2x10 10 cm -2 , which serve as efficient centers of carrier localization, giving rise to effective spatial separation of defective regions and regions of radiative recombination and, as a result, a higher quantum efficiency. Laser structures for optical pumping in the (Zn, Mg) (S, Se) system with a record-low threshold power density (less than 4 kW/cm 2 at 300 K) and continuous-wave laser diodes in the system (Be, Mg, Zn) Se with a 2.5 to 2.8-ML-thick, fractional-monolayer CdSe active region have been obtained. The laser structures and diodes have an improved degradation resistance

  5. Active Power and Flux Control of a Self-Excited Induction Generator for a Variable-Speed Wind Turbine Generation

    Energy Technology Data Exchange (ETDEWEB)

    Na, Woonki; Muljadi, Eduard; Leighty, Bill; Kim, Jonghoon

    2017-05-11

    A Self-Excited Induction Generation (SEIG) for a variable speed wind turbine generation(VS-WG) is normally considered to be a good candidate for implementation in stand-alone applications such as battery charging, hydrogenation, water pumping, water purification, water desalination, and etc. In this study, we have examined a study on active power and flux control strategies for a SEIG for a variable speed wind turbine generation. The control analysis for the proposed system is carried out by using PSCAD software. In the process, we can optimize the control design of the system, thereby enhancing and expediting the control design procedure for this application. With this study, this control design for a SEIG for VS-WG can become the industry standard for analysis and development in terms of SEIG.

  6. Tactile interactions activate mirror system regions in the human brain.

    Science.gov (United States)

    McKyton, Ayelet

    2011-12-07

    Communicating with others is essential for the development of a society. Although types of communications, such as language and visual gestures, were thoroughly investigated in the past, little research has been done to investigate interactions through touch. To study this we used functional magnetic resonance imaging. Twelve participants were scanned with their eyes covered while stroking four kinds of items, representing different somatosensory stimuli: a human hand, a realistic rubber hand, an object, and a simple texture. Although the human and the rubber hands had the same overall shape, in three regions there was significantly more blood oxygen level dependent activation when touching the real hand: the anterior medial prefrontal cortex, the ventral premotor cortex, and the posterior superior temporal cortex. The last two regions are part of the mirror network and are known to be activated through visual interactions such as gestures. Interestingly, in this study, these areas were activated through a somatosensory interaction. A control experiment was performed to eliminate confounds of temperature, texture, and imagery, suggesting that the activation in these areas was correlated with the touch of a human hand. These results reveal the neuronal network working behind human tactile interactions, and highlight the participation of the mirror system in such functions.

  7. Designing Superoxide-Generating Quantum Dots for Selective Light-Activated Nanotherapy

    Science.gov (United States)

    Goodman, Samuel M.; Levy, Max; Li, Fei-Fei; Ding, Yuchen; Courtney, Colleen M.; Chowdhury, Partha P.; Erbse, Annette; Chatterjee, Anushree; Nagpal, Prashant

    2018-03-01

    The rapid emergence of superbugs or multi-drug resistant (MDR) organisms has prompted a search for novel antibiotics, beyond traditional small-molecule therapies. Nanotherapeutics are being investigated as alternatives, and recently superoxide-generating quantum dots (QDs) have been shown as important candidates for selective light-activated therapy and potentiating existing antibiotics against MDR superbugs. Their therapeutic action is selective, can be tailored by simply changing their quantum-confined conduction-valence bands and their alignment with different redox half-reactions, and hence their ability to generate specific radical species in biological media. Here, we show the design of superoxide-generating QDs using optimal QD material and size well matched to superoxide redox potential, charged ligands to modulate their uptake in cells and selective redox interventions, and core/shell structures to improve their stability for therapeutic action. We show that cadmium telluride (CdTe) QDs with conduction band position at -0.5V with respect to Normal Hydrogen Electron (NHE) and visible 2.4 eV bandgap generate a large flux of selective superoxide radicals, thereby demonstrating the most effective light-activated therapy. Although the positively charged QDs demonstrate large cellular uptake, they bind indiscriminately to cell surfaces and cause non-selective cell death, while negatively charged and zwitterionic QD ligands reduce the uptake and allow selective therapeutic action via interaction with redox species. The stability of designed QDs in biologically-relevant media increases with the formation of core-shell QD structures, but an appropriate design of core-shell structures is needed to minimize any reduction in charge injection efficiency to adsorbed oxygen molecules (to form superoxide) and maintain similar quantitative generation of tailored redox species, as measured using electron paramagnetic resonance (EPR) spectroscopy and electrochemical

  8. Designing Superoxide-Generating Quantum Dots for Selective Light-Activated Nanotherapy.

    Science.gov (United States)

    Goodman, Samuel M; Levy, Max; Li, Fei-Fei; Ding, Yuchen; Courtney, Colleen M; Chowdhury, Partha P; Erbse, Annette; Chatterjee, Anushree; Nagpal, Prashant

    2018-01-01

    The rapid emergence of superbugs, or multi-drug resistant (MDR) organisms, has prompted a search for novel antibiotics, beyond traditional small-molecule therapies. Nanotherapeutics are being investigated as alternatives, and recently superoxide-generating quantum dots (QDs) have been shown as important candidates for selective light-activated therapy, while also potentiating existing antibiotics against MDR superbugs. Their therapeutic action is selective, can be tailored by simply changing their quantum-confined conduction-valence band (CB-VB) positions and alignment with different redox half-reactions-and hence their ability to generate specific radical species in biological media. Here, we show the design of superoxide-generating QDs using optimal QD material and size well-matched to superoxide redox potential, charged ligands to modulate their uptake in cells and selective redox interventions, and core/shell structures to improve their stability for therapeutic action. We show that cadmium telluride (CdTe) QDs with conduction band (CB) position at -0.5 V with respect to Normal Hydrogen Electron (NHE) and visible 2.4 eV bandgap generate a large flux of selective superoxide radicals, thereby demonstrating the effective light-activated therapy. Although the positively charged QDs demonstrate large cellular uptake, they bind indiscriminately to cell surfaces and cause non-selective cell death, while negatively charged and zwitterionic QD ligands reduce the uptake and allow selective therapeutic action via interaction with redox species. The stability of designed QDs in biologically-relevant media increases with the formation of core-shell QD structures, but an appropriate design of core-shell structures is needed to minimize any reduction in charge injection efficiency to adsorbed oxygen molecules (to form superoxide) and maintain similar quantitative generation of tailored redox species, as measured using electron paramagnetic resonance (EPR) spectroscopy and

  9. Central Asia in a Changing World: From a Peripheral Region to an Area of Policy Generation and Application. Actors, Policy and Security

    Directory of Open Access Journals (Sweden)

    Nora Sainz Gsell

    2005-10-01

    Full Text Available This work deals with Central Asia, beginning with an analysis of the characteristics of international insertion of the area as a whole and of the former Soviet republics that comprise it. In a general way, it aims to analyse the evolution of Central Asia from a peripheral region to an area that generates behaviours and receives the application of policies on the part ofinternational actors. In the first part of the study, it mentions a series of particularities of the republics that have determined the relationships in the region(the Central Asian order and those between the region and the outside world; it indicates geo-historical and economic-strategic aspects. In the second part, it examines the foreign policy of the republics in the post-Cold War era from the singularities of domestic policy. And, in the third part, it analyses, according to the aforementioned peculiarities, the policies that the area and each State has generated in international actors, both regional ones and global ones, and which have transformed the region from a peripheral one to a geopolitically emerging one.

  10. Transcriptional activation by the E1A regions of adenovirus types 40 and 41

    NARCIS (Netherlands)

    Loon, A.E. van; Gilardi, P.; Perricaudet, M.; Rozijn, Th. H.; Sussenbach, J.S.

    In order to establish whether the poor growth of the two fastidious adenoviruses types 40 and 41 (Ad40 and Ad41) in HeLa cells is due to a reduced trans-activation by the early region to (E1A), we have determined the trans-activating effect of this region on the expression of the chloramphenicol

  11. The discrete and localized nature of the variable emission from active regions

    Science.gov (United States)

    Arndt, Martina Belz; Habbal, Shadia Rifai; Karovska, Margarita

    1994-01-01

    Using data from the Extreme Ultraviolet (EUV) Spectroheliometer on Skylab, we study the empirical characteristics of the variable emission in active regions. These simultaneous multi-wavelength observations clearly confirm that active regions consist of a complex of loops at different temperatures. The variable emission from this complex has very well-defined properties that can be quantitatively summarized as follows: (1) It is localized predominantly around the footpoints where it occurs at discrete locations. (2) The strongest variability does not necessarily coincide with the most intense emission. (3) The fraction of the area of the footpoints, (delta n)/N, that exhibits variable emission, varies by +/- 15% as a function of time, at any of the wavelengths measured. It also varies very little from footpoint to footpoint. (4) This fractional variation is temperature dependent with a maximum around 10(exp 5) K. (5) The ratio of the intensity of the variable to the average background emission, (delta I)/(bar-I), also changes with temperature. In addition, we find that these distinctive characteristics persist even when flares occur within the active region.

  12. LIGHT BRIDGE IN A DEVELOPING ACTIVE REGION. I. OBSERVATION OF LIGHT BRIDGE AND ITS DYNAMIC ACTIVITY PHENOMENA

    International Nuclear Information System (INIS)

    Toriumi, Shin; Katsukawa, Yukio; Cheung, Mark C. M.

    2015-01-01

    Light bridges, the bright structures that divide the umbra of sunspots and pores into smaller pieces, are known to produce a wide variety of activity events in solar active regions (ARs). It is also known that the light bridges appear in the assembling process of nascent sunspots. The ultimate goal of this series of papers is to reveal the nature of light bridges in developing ARs and the occurrence of activity events associated with the light bridge structures from both observational and numerical approaches. In this first paper, exploiting the observational data obtained by Hinode, the Interface Region Imaging Spectrograph, and the Solar Dynamics Observatory, we investigate the detailed structure of the light bridge in NOAA AR 11974 and its dynamic activity phenomena. As a result, we find that the light bridge has a weak, horizontal magnetic field, which is transported from the interior by a large-scale convective upflow and is surrounded by strong, vertical fields of adjacent pores. In the chromosphere above the bridge, a transient brightening occurs repeatedly and intermittently, followed by a recurrent dark surge ejection into higher altitudes. Our analysis indicates that the brightening is the plasma heating due to magnetic reconnection at lower altitudes, while the dark surge is the cool, dense plasma ejected from the reconnection region. From the observational results, we conclude that the dynamic activity observed in a light bridge structure such as chromospheric brightenings and dark surge ejections are driven by magnetoconvective evolution within the light bridge and its interaction with the surrounding magnetic fields

  13. LIGHT BRIDGE IN A DEVELOPING ACTIVE REGION. I. OBSERVATION OF LIGHT BRIDGE AND ITS DYNAMIC ACTIVITY PHENOMENA

    Energy Technology Data Exchange (ETDEWEB)

    Toriumi, Shin; Katsukawa, Yukio [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Cheung, Mark C. M., E-mail: shin.toriumi@nao.ac.jp [Lockheed Martin Solar and Astrophysics Laboratory, 3251 Hanover Street, Building/252, Palo Alto, CA 94304 (United States)

    2015-10-01

    Light bridges, the bright structures that divide the umbra of sunspots and pores into smaller pieces, are known to produce a wide variety of activity events in solar active regions (ARs). It is also known that the light bridges appear in the assembling process of nascent sunspots. The ultimate goal of this series of papers is to reveal the nature of light bridges in developing ARs and the occurrence of activity events associated with the light bridge structures from both observational and numerical approaches. In this first paper, exploiting the observational data obtained by Hinode, the Interface Region Imaging Spectrograph, and the Solar Dynamics Observatory, we investigate the detailed structure of the light bridge in NOAA AR 11974 and its dynamic activity phenomena. As a result, we find that the light bridge has a weak, horizontal magnetic field, which is transported from the interior by a large-scale convective upflow and is surrounded by strong, vertical fields of adjacent pores. In the chromosphere above the bridge, a transient brightening occurs repeatedly and intermittently, followed by a recurrent dark surge ejection into higher altitudes. Our analysis indicates that the brightening is the plasma heating due to magnetic reconnection at lower altitudes, while the dark surge is the cool, dense plasma ejected from the reconnection region. From the observational results, we conclude that the dynamic activity observed in a light bridge structure such as chromospheric brightenings and dark surge ejections are driven by magnetoconvective evolution within the light bridge and its interaction with the surrounding magnetic fields.

  14. How Activism Features in the Career Lives of Four Generations of Canadian Nurses.

    Science.gov (United States)

    MacDonnell, Judith A; Buck-McFadyen, Ellen

    2016-11-01

    Recent nursing research using a critical feminist lens challenges the prevailing view of political inertia in nursing. This comparative life history study using a critical feminist lens explores the relevance of activism with four generations of Canadian nurses. Purposeful sampling of Ontario nurses resulted in 40 participants who were diverse in terms of generation, practice setting, and activist practice. Interviews and focus groups were completed with the sample of Ontario registered nurses or undergraduate and graduate nursing students: 8 Generation X, 9 Generation Y (Millennials), 20 Boomers, and 3 Overboomers. Factors such as professional norms and personal and organizational supports shaped contradictory nursing activist identities, practices, and impacts. Gendered norms, organizational dynamics, and the political landscape influenced the meanings nurses attributed to critical incidents and influences that prompted activism inside and outside the workplace, shaping the transformative potential of nursing. Despite its limitations, the study has implications for creating professional and organizational supports for consideration of health politics and policy, and spaces for dialogue to support practice and research aligned with social justice goals.

  15. Volcanic and Tectonic Activity in the Red Sea Region (2004-2013): Insights from Satellite Radar Interferometry and Optical Imagery

    KAUST Repository

    Xu, Wenbin

    2015-04-01

    Studying recent volcanic and tectonic events in the Red Sea region is important for improving our knowledge of the Red Sea plate boundary and for regional geohazard assessments. However, limited information has been available about the past activity due to insufficient in-situ data and remoteness of some of the activity. In this dissertation, I have used satellite remote sensing to derive new information about several recent volcanic and tectonic events in the Red Sea region. I first report on three volcanic eruptions in the southern Red Sea, the 2007-8 Jebel at Tair eruption and the 2011-12 & 2013 Zubair eruptions, which resulted in formation of two new islands. Series of high- resolution optical images were used to map the extent of lava flows and to observe and analyze the growth and destructive processes of the new islands. I used Interferometric Synthetic Aperture Radar (InSAR) data to study the evolution of lava flows, to estimate their volumes, as well as to generate ground displacements maps, which were used to model the dikes that fed the eruptions. I then report on my work of the 2009 Harrat Lunayyir dike intrusion and the 2004 Tabuk earthquake sequence in western Saudi Arabia. I used InSAR observations and stress calculations to study the intruding dike at Harrat Lunayyir, while I combined InSAR data and Bayesian estimation to study the Tabuk earthquake activity. The key findings of the thesis are: 1) The recent volcanic eruptions in the southern Red Sea indicate that the area is magmatically more active than previously acknowledged and that a rifting episode has been taken place in the southern Red Sea; 2) Stress interactions between an ascending dike intrusion and normal faulting on graben-bounding faults above the dike can inhibit vertical propagation of magma towards the surface; 3) InSAR observations can improve locations of shallow earthquakes and fault model uncertainties are useful to associate earthquake activity with mapped faults; 4). The

  16. Effects of a power shortage in the Tokyo metropolitan area on awareness of nuclear power generation and power savings behavior

    International Nuclear Information System (INIS)

    Kitada, Atsuko

    2004-01-01

    The shutdown of a number of nuclear power stations of the Tokyo Electric Power Company in the summer of 2003 caused a power shortage problem in the Tokyo Metropolitan area. To examine the effects of the power shortage, in September 2003 a survey was conducted in the service areas of the Kansai Electric Power Company (Kansai region) and the Tokyo Electric Power Company (Kanto region). This survey was part of a wider opinion survey begun in 1993 concerning nuclear power generation. The results of the September 2003 survey are as follows: The degree of recognition of the power shortage problem in the Metropolitan area was high, with 40% of respondents in the Kansai region and nearly 70% in the Kanto region understanding that the shortage was caused by the shutdown of several nuclear power station. The overall awareness of nuclear power generation was little affected in both the Kansai and Kanto regions, though the sense of a shortage of the generating capacity had been raised slightly. Once respondents knew about the power shortage problem, they estimated the likelihood of an occurrence of large-scale service interruption to be low, nearly at an even chance, and they had been only slightly worried about it, essentially viewing the problem optimistically. In the Kanto region, where public relations activities for power savings had been actively pursued, the frequency of experiencing exposure to such public relations activities was remarkably higher than in the Kansai region. The relation between exposure to public relations activities for power savings and power savings behavior was analyzed using quantification method II. Analysis results suggest that public relations activities for power savings in the Kanto region had the effect of urging power savings behavior. However, the difference in the rate of putting power savings behavior into practice was small between the Kanto and Kansai regions, indicating that public relation activities for power savings in the Kanto

  17. Activation analysis with neutron generators using short-lived radionuclides

    International Nuclear Information System (INIS)

    Salma, I.

    1993-01-01

    The short half-life involves a number of important differences in production, transportation and measurement of radionuclides, and in counting statistics as compared with those in traditional activation analysis. Experiments were performed to investigate the analytical possibilities and prospective utilization of short-lived radionuclides produced by 14-MeV neutron irradiation. A rapid pneumatic transfer system for use with neutron generators was installed and applied for detecting radionuclides with a half-life from 300 ms to 30 s. The transport time for samples with a total mass of 1-4 g is between 130 and 160 ms for pressurized air of 0.1-0.4 MPa. 11 elements were studied by the conventional activation method using both a typical pneumatic transport system (run time 3 s) and the fast pneumatic transport facility. The effect of the cyclic activation technique on the elemental sensitivities was also investigated. (orig.)

  18. 50 CFR 216.211 - Specified activity and specified geographical region.

    Science.gov (United States)

    2010-10-01

    ... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking of Marine Mammals Incidental to Explosive Severance.... Gulf of Mexico § 216.211 Specified activity and specified geographical region. (a) Regulations in this...

  19. 50 CFR 216.250 - Specified activity and specified geographical region.

    Science.gov (United States)

    2010-10-01

    ... OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to Conducting Precision Strike Weapon Missions in the Gulf of Mexico § 216.250 Specified activity and specified geographical region. (a...

  20. Empirical Analysis of the Integration Activity of Business Structures in the Regions of Russia

    Directory of Open Access Journals (Sweden)

    Maria Gennadyevna Karelina

    2015-12-01

    Full Text Available The article investigates the integration activity of business structures in the regions of Russia. A wide variety of approaches to the study of the problems and prospects of economic integration and the current dispute on the role of integration processes in the regional economic development have determined the complexity of the concepts “integration” and “integration activities” in order to develop the objective conditions to analyse the integration activity of business structures in the Russian regions. The monitoring of the current legal system of the Russian Federation carried out in the area of statistics and compiling statistical databases on mergers and acquisitions has showed the absence of the formal executive authority dealing with the compiling and collections of information on the integration activity at the regional level. In this connection, the data of Russian information and analytical agencies are made from the information and analytical base. As the research tools, the methods of analysis of structural changes, methods of analysis of economic differentiation and concentration, methods of non-parametric statistics are used. The article shows the close relationship between the social and economic development of the subjects of Russia and the integrated business structures functioning on its territory. An investigation of the integration activity structure and dynamics in the subjects of the Russian Federation based on the statistical data for the period from 2003 to 2012 has revealed the increasing heterogeneity of the integration activity of business structures in the regions of Russia. The hypothesis of a substantial divergence of mergers and acquisitions of corporate structures in the Russian regions was confirmed by the high values of the Gini coefficient, the Herfindahl index, and the decile coefficient of differentiation. The research results are of practical importance since they can be used to improve the existing

  1. Perspective usage estimation of Volga region combustible shale as a power generating fuel alternative

    Science.gov (United States)

    Korolev, E.; Barieva, E.; Eskin, A.

    2018-05-01

    A comprehensive study of combustible shale, common within Tatarstan and Ulyanovsk region, is carried out. The rocks physicochemical parameters are found to meet the power generating fuels requirements. The predictive estimate of ash products properties of combustible shale burning is held. Minding furnace process technology it is necessary to know mineral and organic components behavior when combustible shale is burnt. Since the first will determine slagging properties of energy raw materials, the second – its calorific value. In consideration of this the main research methods were X-ray, thermal and X-ray fluorescence analyses. Summing up the obtained results, we can draw to the following conclusions: 1. The combustible shale in Tatarstan and the Ulyanovsk region has predominantly low calorific value (Qb d = 5-9 MJ/kg). In order to enhance its efficiency and to reduce cost it is possible to conduct rocks burning together with some other organic or organic mineral power generating fuels. 2. High ash content (Ad = 60-80%) that causes a high external ballast content in shale implies the appropriateness of using this fuel resource next to its exploitation site. The acceptable distance to a consumer will reduce unproductive transportation charges for large ash and moisture masses. 3. The performed fuel ash components characteristics, as well as the yield and volatiles composition allow us to specify the basic parameters for boiler units, designed for the Volga combustible shale burning. 4. The noncombustible residual components composition shows that shale ash can be used in manufacture of materials of construction.

  2. Efficient peroxydisulfate activation process not relying on sulfate radical generation for water pollutant degradation

    KAUST Repository

    Zhang, Tao; Chen, Yin; Wang, Yuru; Le Roux, Julien; Yang, Yang; Croue, Jean-Philippe

    2014-01-01

    Peroxydisulfate (PDS) is an appealing oxidant for contaminated groundwater and toxic industrial wastewaters. Activation of PDS is necessary for application because of its low reactivity. Present activation processes always generate sulfate radicals

  3. Micropipette force probe to quantify single-cell force generation: application to T-cell activation.

    Science.gov (United States)

    Sawicka, Anna; Babataheri, Avin; Dogniaux, Stéphanie; Barakat, Abdul I; Gonzalez-Rodriguez, David; Hivroz, Claire; Husson, Julien

    2017-11-07

    In response to engagement of surface molecules, cells generate active forces that regulate many cellular processes. Developing tools that permit gathering mechanical and morphological information on these forces is of the utmost importance. Here we describe a new technique, the micropipette force probe, that uses a micropipette as a flexible cantilever that can aspirate at its tip a bead that is coated with molecules of interest and is brought in contact with the cell. This technique simultaneously allows tracking the resulting changes in cell morphology and mechanics as well as measuring the forces generated by the cell. To illustrate the power of this technique, we applied it to the study of human primary T lymphocytes (T-cells). It allowed the fine monitoring of pushing and pulling forces generated by T-cells in response to various activating antibodies and bending stiffness of the micropipette. We further dissected the sequence of mechanical and morphological events occurring during T-cell activation to model force generation and to reveal heterogeneity in the cell population studied. We also report the first measurement of the changes in Young's modulus of T-cells during their activation, showing that T-cells stiffen within the first minutes of the activation process. © 2017 Sawicka et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  4. Atmospheric conditions associated with extreme fire activity in the Western Mediterranean region.

    Science.gov (United States)

    Amraoui, Malik; Pereira, Mário G; DaCamara, Carlos C; Calado, Teresa J

    2015-08-15

    Active fire information provided by TERRA and AQUA instruments on-board sun-synchronous polar MODIS platform is used to describe fire activity in the Western Mediterranean and to identify and characterize the synoptic patterns of several meteorological fields associated with the occurrence of extreme fire activity episodes (EEs). The spatial distribution of the fire pixels during the period of 2003-2012 leads to the identification of two most affected sub-regions, namely the Northern and Western parts of the Iberian Peninsula (NWIP) and Northern Africa (NAFR). The temporal distribution of the fire pixels in these two sub-regions is characterized by: (i) high and non-concurrent inter- and intra-annual variability with maximum values during the summer of 2003 and 2005 in NWIP and 2007 and 2012 in NAFR; and, (ii) high intra-annual variability dominated by a prominent annual cycle with a main peak centred in August in both sub-regions and a less pronounced secondary peak in March only evident in NWIP region. The 34 EEs identified were grouped according to the location, period of occurrence and spatial configuration of the associated synoptic patterns into 3 clusters (NWIP-summer, NWIP-winter and NAFR-summer). Results from the composite analysis reveal similar fire weather conditions (statistically significant positive anomalies of air temperature and negative anomalies of air relative humidity) but associated with different circulation patterns at lower and mid-levels of the atmosphere associated with the occurrence of EEs in each cluster of the Western Mediterranean region. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Functional Connectivity of Multiple Brain Regions Required for the Consolidation of Social Recognition Memory.

    Science.gov (United States)

    Tanimizu, Toshiyuki; Kenney, Justin W; Okano, Emiko; Kadoma, Kazune; Frankland, Paul W; Kida, Satoshi

    2017-04-12

    Social recognition memory is an essential and basic component of social behavior that is used to discriminate familiar and novel animals/humans. Previous studies have shown the importance of several brain regions for social recognition memories; however, the mechanisms underlying the consolidation of social recognition memory at the molecular and anatomic levels remain unknown. Here, we show a brain network necessary for the generation of social recognition memory in mice. A mouse genetic study showed that cAMP-responsive element-binding protein (CREB)-mediated transcription is required for the formation of social recognition memory. Importantly, significant inductions of the CREB target immediate-early genes c-fos and Arc were observed in the hippocampus (CA1 and CA3 regions), medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), and amygdala (basolateral region) when social recognition memory was generated. Pharmacological experiments using a microinfusion of the protein synthesis inhibitor anisomycin showed that protein synthesis in these brain regions is required for the consolidation of social recognition memory. These findings suggested that social recognition memory is consolidated through the activation of CREB-mediated gene expression in the hippocampus/mPFC/ACC/amygdala. Network analyses suggested that these four brain regions show functional connectivity with other brain regions and, more importantly, that the hippocampus functions as a hub to integrate brain networks and generate social recognition memory, whereas the ACC and amygdala are important for coordinating brain activity when social interaction is initiated by connecting with other brain regions. We have found that a brain network composed of the hippocampus/mPFC/ACC/amygdala is required for the consolidation of social recognition memory. SIGNIFICANCE STATEMENT Here, we identify brain networks composed of multiple brain regions for the consolidation of social recognition memory. We

  6. Renewable generation across Italian regions: Spillover effects and effectiveness of European Regional Fund

    International Nuclear Information System (INIS)

    Carfora, Alfonso; Romano, Antonio A.; Ronghi, Monica; Scandurra, Giuseppe

    2017-01-01

    This paper investigates on the determinant factors that drive the Italian regions toward a sustainable development path and evaluates the effectiveness of European Regional Development incentives in promoting investments in renewable energy sources (RES). Starting from the consideration that there are spillover effects between similar regions, first we identify the factors that capture these similarities, then we use them to evaluate their relevance in determining the success of the investments in RES. An econometric analysis, based on the use of spatial panel specification model, is implemented to support the hypotheses. Two important results emerge from the study. The first is the identification of regional determinants of RES production, that are driven by the similarities between regions, and that can be interpreted as guidelines in the policy choices in support of investments. The second is the lack of effectiveness of the incentives in support of RES. Results indicate that the capacity of some regional governments to direct the funds allocated by the central government or European Commission towards efficient production of renewable energy is likely limited, and these incentives have been undone. - Highlights: • Investments in renewable energies makes a remarkable contribution to reduce unemployment. • In Italy there is a lack of effectiveness of the incentives in support of renewable energies. • To attract energy investments regions must reduce the burden of taxation. • Highly deprived areas incentivize more than the developed ones renewable energies. • Production of renewable energies is directly influenced by the production in similar regions.

  7. The Stimulating Mechanisms Of Regional Economic Activity In Spain: Lessous For Russia

    Directory of Open Access Journals (Sweden)

    K. S. Seredinskaya

    2017-01-01

    Full Text Available Spain is a country that traditionally suffers a lot from high level of regional disparities. From the end of XX century Spanish government has taken different measures to smooth them. For example, the state of autonomies was established, statutes were approved for every region, more powers were transferred to regional authorities. There are several institutions in Spain that increase the efficiency of cooperation between different levels of authorities and between autonomies, such as conference of the presidents, sectoral conferences, agreements on cooperation and bilateral commissions. Activity of these mechanisms is of a great interest for the author. The author tries to find the ways to modernize Russian regional policy using Spanish experience, considering its pros and cons. Undoubtedly it is impossible to copy other countries practice as Russia and Spain differ a lot, for example, in size, population, the level of socialeconomic development and the supply of mineral resources. Still there is something in common, like high level of regional disparities and amount of authorities the territories obtain. Even though Spain is a unitary state, its autonomies are quite independent. Territorial status of the country is a hybrid between unitary and federative state. Its institutional structure of regional policy is pretty diversified. So both these aspects are worth considering. Regional policy is one the most important directions of the state activity in Russia, because of its extensive territories. Today Russia has to face a number of regional challenges and regional policy cannot cope with them. The growing territorial polarization slow down the development of the whole country. It is useful to analyze foreign institutions, which solve regional problems in the other states, to adapt their practice to the Russian realities.

  8. Development of high flux thermal neutron generator for neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Vainionpaa, Jaakko H., E-mail: hannes@adelphitech.com [Adelphi Technology, 2003 E Bayshore Rd, Redwood City, CA 94063 (United States); Chen, Allan X.; Piestrup, Melvin A.; Gary, Charles K. [Adelphi Technology, 2003 E Bayshore Rd, Redwood City, CA 94063 (United States); Jones, Glenn [G& J Jones Enterprice, 7486 Brighton Ct, Dublin, CA 94568 (United States); Pantell, Richard H. [Department of Electrical Engineering, Stanford University, Stanford, CA (United States)

    2015-05-01

    The new model DD110MB neutron generator from Adelphi Technology produces thermal (<0.5 eV) neutron flux that is normally achieved in a nuclear reactor or larger accelerator based systems. Thermal neutron fluxes of 3–5 · 10{sup 7} n/cm{sup 2}/s are measured. This flux is achieved using four ion beams arranged concentrically around a target chamber containing a compact moderator with a central sample cylinder. Fast neutron yield of ∼2 · 10{sup 10} n/s is created at the titanium surface of the target chamber. The thickness and material of the moderator is selected to maximize the thermal neutron flux at the center. The 2.5 MeV neutrons are quickly thermalized to energies below 0.5 eV and concentrated at the sample cylinder. The maximum flux of thermal neutrons at the target is achieved when approximately half of the neutrons at the sample area are thermalized. In this paper we present simulation results used to characterize performance of the neutron generator. The neutron flux can be used for neutron activation analysis (NAA) prompt gamma neutron activation analysis (PGNAA) for determining the concentrations of elements in many materials. Another envisioned use of the generator is production of radioactive isotopes. DD110MB is small enough for modest-sized laboratories and universities. Compared to nuclear reactors the DD110MB produces comparable thermal flux but provides reduced administrative and safety requirements and it can be run in pulsed mode, which is beneficial in many neutron activation techniques.

  9. New digital reference current generation for shunt active power filter under distorted voltage conditions

    Energy Technology Data Exchange (ETDEWEB)

    Abdusalam, Mohamed; Karimi, Shahram; Saadate, Shahrokh [Groupe de Recherche en Electrotechnique et Electronique de Nancy (GREEN), CNRS UMR 7037 (France); Poure, Philippe [Laboratoire d' Instrumentation Electronique de Nancy (LIEN), EA 3440, Universite Henri Poincare - Nancy Universite, B.P. 239, 54506 Vandoeuvre les Nancy Cedex (France)

    2009-05-15

    In this paper, a new reference current computation method suitable for shunt active power filter control under distorted voltage conditions is proposed. The active power filter control is based on the use of self-tuning filters (STF) for the reference current generation and on a modulated hysteresis current controller. This active filter is intended for harmonic compensation of a diode rectifier feeding a RL load under distorted voltage conditions. The study of the active filter control is divided in two parts. The first one deals with the harmonic isolator which generates the harmonic reference currents and is experimentally implemented in a DS1104 card of a DSPACE prototyping system. The second part focuses on the generation of the switching pattern of the inverter by using a modulated hysteresis current controller, implemented in an analogue card. The use of STF instead of classical extraction filters allows extracting directly the voltage and current fundamental components in the {alpha}-{beta} axis without phase locked loop (PLL). The performances are good even under distorted voltage conditions. First, the effectiveness of the new proposed method is mathematically studied and verified by computer simulation. Then, experimental results are presented using a DSPACE system associated with the analogue current controller for a real shunt active power filter. (author)

  10. Flow Orientation Analysis for Major Activity Regions Based on Smart Card Transit Data

    Directory of Open Access Journals (Sweden)

    Parul Singh

    2017-10-01

    Full Text Available Analyzing public movement in transportation networks in a city is significant in understanding the life of citizen and making improved city plans for the future. This study focuses on investigating the flow orientation of major activity regions based on smart card transit data. The flow orientation based on the real movements such as transit data can provide the easiest way of understanding public movement in the complicated transportation networks. First, high inflow regions (HIRs are identified from transit data for morning and evening peak hours. The morning and evening HIRs are used to represent major activity regions for major daytime activities and residential areas, respectively. Second, the directional orientation of flow is then derived through the directional inflow vectors of the HIRs to show the bias in directional orientation and compare flow orientation among major activity regions. Finally, clustering analysis for HIRs is applied to capture the main patterns of flow orientations in the city and visualize the patterns on the map. The proposed methodology was illustrated with smart card transit data of bus and subway transportation networks in Seoul, Korea. Some remarkable patterns in the distribution of movements and orientations were found inside the city. The proposed methodology is useful since it unfolds the complexity and makes it easy to understand the main movement patterns in terms of flow orientation.

  11. Regional cholinesterase activity in white-throated sparrow brain is differentially affected by acephate (Orthene®)

    Science.gov (United States)

    Vyas, N.B.; Kuenzel, W.J.; Hill, E.F.; Romo, G.A.; Komaragiri, M.V.S.

    1996-01-01

    Effects of a 14-day dietary exposure to an organophosphorus pesticide, acephate (acetylphosphoramidothioic acid O,S-dimethyl ester), were determined on cholinesterase activity in three regions (basal ganglia, hippocampus, and hypothalamus) of the white-throated sparrow, Zonotrichia albicollis, brain. All three regions experienced depressed cholinesterase activity between 0.5–2 ppm acephate. The regions exhibited cholinesterase recovery at 2–16 ppm acephate; however, cholinesterase activity dropped and showed no recovery at higher dietary levels (>16 ppm acephate). Evidence indicates that the recovery is initiated by the magnitude of depression, not the duration. In general, as acephate concentration increased, differences in ChE activity among brain regions decreased. Three terms are introduced to describe ChE response to acephate exposure: 1) ChE resistance threshold, 2) ChE compensation threshold, and 3) ChE depression threshold. It is hypothesized that adverse effects to birds in the field may occur at pesticide exposure levels customarily considered negligible.

  12. Marginal Generation Technology in the Chinese Power Market towards 2030 Based on Consequential Life Cycle Assessment

    DEFF Research Database (Denmark)

    Zhao, Guangling; Guerrero, Josep M.; Pei, Yingying

    2016-01-01

    Electricity consumption is often the hotspot of life cycle assessment (LCA) of products, industrial activities, or services. The objective of this paper is to provide a consistent, scientific, region-specific electricity-supply-based inventory of electricity generation technology for national...... and regional power grids. Marginal electricity generation technology is pivotal in assessing impacts related to additional consumption of electricity. China covers a large geographical area with regional supply grids; these are arguably equally or less integrated. Meanwhile, it is also a country with internal...

  13. The Activities, Roles, and Relationships of Successful First-Generation College Students

    Science.gov (United States)

    Demetriou, Cynthia; Meece, Judith; Eaker-Rich, Deborah; Powell, Candice

    2017-01-01

    This qualitative study describes the experiences of 16 successful first-generation college students (FGCS) utilizing a theoretical lens, informed significantly by bioecological systems theory (Bronfenbrenner, 1979), which guided our qualitative analyses of interview transcripts to examine the activities, roles, and relationships of these students…

  14. Multi-wavelength fiber laser in the S-band region using a Sagnac loop mirror as a comb generator in an SOA gain medium

    International Nuclear Information System (INIS)

    Zulkifli, M Z; Hassan, N A; Awang, N A; Ahmad, H; Ghani, Z A; Harun, S W

    2010-01-01

    A simple design of multi-wavelength generation in the S-band region of the optical network transmission is proposed. The design consists of broad-band fiber Bragg grating (BB-FBG), which acts as a filter to enhance operation in the S-band region. A Sagnac loop mirror (SLM) is used to generate multiple wavelength oscillations in the ring cavity. The output consists of 60 lasing wavelengths oscillating simultaneously between 1464 nm and 1521 nm with a spacing of 0.92 nm and an output linewidth of 0.66 nm

  15. Modern Integration Processes in the Asia-Pacific Region: the Formation of Trans-Regional Mega-Agreements

    Directory of Open Access Journals (Sweden)

    Maliuta Iryna A.

    2017-12-01

    Full Text Available In the 21st century, especially in the last decade, new intercontinental integration projects appear on the global stage with a high potential for influencing the regional economic structure and at the same time bearing certain challenges for the international geo-economic and geo-political map of the world. Comprehensive new-generation inter-regional agreements are being formed, such as the TTP, the TTIP, the RCEP, the Comprehensive Economic and Trade Agreement between Canada and the EU (CETA, the Japan-EU Economic Partnership. The Asia-Pacific region has been an active participant in the creation and promotion of mega-regional trade agreements. Mega-regional trade agreements in the Asia-Pacific region, namely the TTP and the RCEP, are analyzed as mega-projects with an unprecedented scale of liberalization within the framework of the agreement that include provisions complementing the WTO framework or extending beyond it. There identified reasons for the emergence of mega-regional trade agreements and prospects for the implementation of these projects, as well as possible consequences for the international economic system. It is established that new trans-regional projects, providing certain advantages to the participating countries, simultaneously carry both opportunities and challenges for the world economy. The latter are associated with the threats of crowding the countries that do not take an active part in the integration processes out of the global chains of value creation as well as of the processes of international trade.

  16. Alternative energy and distributed generation: thinking generations ahead

    International Nuclear Information System (INIS)

    Hunt, P.D.

    2001-01-01

    Alternative Energy will be discussed in the context of Distributed Generation, which is defined as a delivery platform for micro-power generation, close to the end-users, that can also supplement regional electricity grids. Many references in the paper pertain to Alberta. This is for two reasons: First, familiarity by the author, and more importantly, Alberta is the first region in Canada that has de-regulated it's electricity sector. De-regulation allows independent and smaller power generators to enter the market. Focussing on Alberta, with some references to other Canadian provinces and USA, electricity consumption trends will be reviewed and the pressures to decentralize electricity generation discussed. Re-structuring of the electricity sector, convergence of power generation and natural gas industries, advances in technologies, and environmental concerns are collectively contributing to the creation of a new business called 'Distributed Generation'. Efficiency benefits of combined heat and power associated with the more prominent emerging distributed generation technologies like micro-turbines and fuel cells, will be highlighted. Areas of research, development and demonstration that will enable the successful deployment of Distributed Generation will be suggested with respect to Generation Technologies, Systems Controls, Supporting Infrastructure, and Socio-Political Barriers. Estimates of investments in the various alternative energy technologies will be presented. Using current trends and emerging technologies the Paper will conclude with some predictions of future scenarios. (author)

  17. Magnetic Characteristics of Active Region Heating Observed with TRACE, SOHO/EIT, and Yohkoh/SXT

    Science.gov (United States)

    Porter, J. G.; Falconer, D. A.; Moore, R. L.; Rose, M. Franklin (Technical Monitor)

    2001-01-01

    Over the past several years, we have reported results from studies that have compared the magnetic structure and heating of the transition region and corona (both in active regions and in the quiet Sun) by combining X-ray and EUV images from Yohkoh and Solar and Heliospheric Observatory (SOHO) with photospheric magnetograms from ground-based observatories. Our findings have led us to the hypothesis that most heating throughout the corona is driven from near and below the base of the corona by eruptive microflares occurring in compact low-lying "core magnetic fields (i.e., fields rooted along and closely enveloping polarity inversion lines in the photospheric magnetic flux). We now extend these studies, comparing sequences of UV images from Transition Region and Coronal Explorer (TRACE) with longitudinal magnetograms from Kitt Peak and vector magnetograms from MUSIC. These comparisons confirm the previous results regarding the importance of core-field activity to active region heating. Activity in fields associated with satellite polarity inclusions and/or magnetically sheared configurations is especially prominent. This work is funded by NASA's Office of Space Science through the Sun-Earth Connection Guest Investigator Program and the Solar Physics Supporting Research and Technology Program.

  18. Active Ageing Level of Older Persons: Regional Comparison in Thailand.

    Science.gov (United States)

    Haque, Md Nuruzzaman

    2016-01-01

    Active ageing level and its discrepancy in different regions (Bangkok, Central, North, Northeast, and South) of Thailand have been examined for prioritizing the policy agenda to be implemented. Attempt has been made to test preliminary active ageing models for Thai older persons and hence active ageing index (AAI, ranges from 0 to 1) has been estimated. Using nationally representative data and confirmatory factor analysis approach, this study justified active ageing models for female and male older persons in Thailand. Results revealed that active ageing level of Thai older persons is not high (mean AAIs for female and male older persons are 0.64 and 0.61, resp., and those are significantly different (p active ageing level. Implementation of an Integrated Active Ageing Package (IAAP), containing policies for older persons to improve their health and economic security, to promote participation in social groups and longer working lives, and to arrange learning programs, would be helpful for increasing older persons' active ageing level in Thailand.

  19. Study of the Quality of Life of the Older Generation: a Regional Experience

    Directory of Open Access Journals (Sweden)

    Vitalii Nikolaevich Barsukov

    2016-09-01

    Full Text Available The increase in life expectancy in Russia along with low fertility has led to the fact that the age structure of the population has undergone significant changes: the proportion of children in the total population was continuously reducing, while the share of people over 60 was growing. Such transformations have multiple impacts, ranging from the issues of financial provision of pension systems, functioning of the labor market to the change in the value orientations of society. The growth of socio-demographic groups of elderly people leads to the fact that it is becoming increasingly important for the socio-economic development of territories, thus facilitating research in the field of studying its resource potential and quality of life. The paper is devoted to the study of components of a “subjective” quality of life of the specified group of the population. The authors present conceptual approaches to the problem of an “ageing” society and specifics of studying the quality of life of the elderly. The paper substantiates the importance of sociological assessments in the study of issues typical of the elderly. The authors show the place of Russia in the international ranking of the Global AgeWatch Index and its position for all the four particular indices. Based on the findings of a sociological study, the authors highlight major problem areas that hinder the improvement of the quality of life of the elderly population, and put forward possible ways to level them. The paper considers the main normative legal acts that regulate the activities of federal and regional authorities in ensuring the decent quality of life of this socio-demographic group. The authors discuss several social projects (taking the Vologda Oblast as an example that aim to improve the living conditions of the elderly, highlight the problems associated with the implementation and scientific substantiation of the relevance of these projects. The conclusion is made

  20. Region-dependent hamstrings activity in Nordic hamstring exercise and stiff-leg deadlift defined with high-density electromyography.

    Science.gov (United States)

    Hegyi, A; Péter, A; Finni, T; Cronin, N J

    2018-03-01

    Recent studies suggest region-specific metabolic activity in hamstring muscles during injury prevention exercises, but the neural representation of this phenomenon is unknown. The aim of this study was to examine whether regional differences are evident in the activity of biceps femoris long head (BFlh) and semitendinosus (ST) muscles during two common injury prevention exercises. Twelve male participants without a history of hamstring injury performed the Nordic hamstring exercise (NHE) and stiff-leg deadlift (SDL) while BFlh and ST activities were recorded with high-density electromyography (HD-EMG). Normalized activity was calculated from the distal, middle, and proximal regions in the eccentric phase of each exercise. In NHE, ST overall activity was substantially higher than in BFlh (d = 1.06 ± 0.45), compared to trivial differences between muscles in SDL (d = 0.19 ± 0.34). Regional differences were found in NHE for both muscles, with different proximal-distal patterns: The distal region showed the lowest activity level in ST (regional differences, d range = 0.55-1.41) but the highest activity level in BFlh (regional differences, d range = 0.38-1.25). In SDL, regional differences were smaller in both muscles (d range = 0.29-0.67 and 0.16-0.63 in ST and BFlh, respectively) than in NHE. The use of HD-EMG in hamstrings revealed heterogeneous hamstrings activity during typical injury prevention exercises. High-density EMG might be useful in future studies to provide a comprehensive overview of hamstring muscle activity in other exercises and high-injury risk tasks. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. The regional electricity generation mix in Scotland. A portfolio selection approach incorporating marine technologies

    Energy Technology Data Exchange (ETDEWEB)

    Allan, Grant; Eromenko, Igor; McGregor, Peter [Fraser of Allander Institute, Department of Economics, University of Strathclyde, Sir William Duncan Building, 130 Rottenrow, Glasgow G4 0GE (United Kingdom); Swales, Kim [Department of Economics, University of Strathclyde, Sir William Duncan Building, 130 Rottenrow, Glasgow G4 0GE (United Kingdom)

    2011-01-15

    Standalone levelised cost assessments of electricity supply options miss an important contribution that renewable and non-fossil fuel technologies can make to the electricity portfolio: that of reducing the variability of electricity costs, and their potentially damaging impact upon economic activity. Portfolio theory applications to the electricity generation mix have shown that renewable technologies, their costs being largely uncorrelated with non-renewable technologies, can offer such benefits. We look at the existing Scottish generation mix and examine drivers of changes out to 2020. We assess recent scenarios for the Scottish generation mix in 2020 against mean-variance efficient portfolios of electricity-generating technologies. Each of the scenarios studied implies a portfolio cost of electricity that is between 22% and 38% higher than the portfolio cost of electricity in 2007. These scenarios prove to be mean-variance 'inefficient' in the sense that, for example, lower variance portfolios can be obtained without increasing portfolio costs, typically by expanding the share of renewables. As part of extensive sensitivity analysis, we find that Wave and Tidal technologies can contribute to lower risk electricity portfolios, while not increasing portfolio cost. (author)

  2. Analysis of the environmental impact generated by nuclear activities

    International Nuclear Information System (INIS)

    Lazar, Roxana Elena; Dumitrescu, Maria

    2000-01-01

    Assessment of environmental impact represents one of the most formalized examples of interdisciplinary approach. After more then a century from the introduction of the concept of environmental impact assessment, this undertaking still represents an amalgamation of mini-studies based on pre-determined approaches rather than a genuine integrated document. This work presents the most important and adequate techniques of analysis of environmental impact generated by nuclear activities starting from identification of the events causing negative effects upon environment (by using checking list, the matrices and the cause-effect diagram) and radiation dose determination up to the decision making process. To preserve environment integrity the human factor should be re-evaluated as well as its active participation in formation and settling of an real environmental culture

  3. The 3D Recognition, Generation, Fusion, Update and Refinement (RG4) Concept

    Science.gov (United States)

    Maluf, David A.; Cheeseman, Peter; Smelyanskyi, Vadim N.; Kuehnel, Frank; Morris, Robin D.; Norvig, Peter (Technical Monitor)

    2001-01-01

    This paper describes an active (real time) recognition strategy whereby information is inferred iteratively across several viewpoints in descent imagery. We will show how we use inverse theory within the context of parametric model generation, namely height and spectral reflection functions, to generate model assertions. Using this strategy in an active context implies that, from every viewpoint, the proposed system must refine its hypotheses taking into account the image and the effect of uncertainties as well. The proposed system employs probabilistic solutions to the problem of iteratively merging information (images) from several viewpoints. This involves feeding the posterior distribution from all previous images as a prior for the next view. Novel approaches will be developed to accelerate the inversion search using novel statistic implementations and reducing the model complexity using foveated vision. Foveated vision refers to imagery where the resolution varies across the image. In this paper, we allow the model to be foveated where the highest resolution region is called the foveation region. Typically, the images will have dynamic control of the location of the foveation region. For descent imagery in the Entry, Descent, and Landing (EDL) process, it is possible to have more than one foveation region. This research initiative is directed towards descent imagery in connection with NASA's EDL applications. Three-Dimensional Model Recognition, Generation, Fusion, Update, and Refinement (RGFUR or RG4) for height and the spectral reflection characteristics are in focus for various reasons, one of which is the prospect that their interpretation will provide for real time active vision for automated EDL.

  4. Cross-modal activation of auditory regions during visuo-spatial working memory in early deafness.

    Science.gov (United States)

    Ding, Hao; Qin, Wen; Liang, Meng; Ming, Dong; Wan, Baikun; Li, Qiang; Yu, Chunshui

    2015-09-01

    Early deafness can reshape deprived auditory regions to enable the processing of signals from the remaining intact sensory modalities. Cross-modal activation has been observed in auditory regions during non-auditory tasks in early deaf subjects. In hearing subjects, visual working memory can evoke activation of the visual cortex, which further contributes to behavioural performance. In early deaf subjects, however, whether and how auditory regions participate in visual working memory remains unclear. We hypothesized that auditory regions may be involved in visual working memory processing and activation of auditory regions may contribute to the superior behavioural performance of early deaf subjects. In this study, 41 early deaf subjects (22 females and 19 males, age range: 20-26 years, age of onset of deafness memory task than did the hearing controls. Compared with hearing controls, deaf subjects exhibited increased activation in the superior temporal gyrus bilaterally during the recognition stage. This increased activation amplitude predicted faster and more accurate working memory performance in deaf subjects. Deaf subjects also had increased activation in the superior temporal gyrus bilaterally during the maintenance stage and in the right superior temporal gyrus during the encoding stage. These increased activation amplitude also predicted faster reaction times on the spatial working memory task in deaf subjects. These findings suggest that cross-modal plasticity occurs in auditory association areas in early deaf subjects. These areas are involved in visuo-spatial working memory. Furthermore, amplitudes of cross-modal activation during the maintenance stage were positively correlated with the age of onset of hearing aid use and were negatively correlated with the percentage of lifetime hearing aid use in deaf subjects. These findings suggest that earlier and longer hearing aid use may inhibit cross-modal reorganization in early deaf subjects. Granger

  5. Distinguishing How from Why the Mind Wanders: A Process-Occurrence Framework for Self-Generated Mental Activity

    Science.gov (United States)

    Smallwood, Jonathan

    2013-01-01

    Cognition can unfold with little regard to the events taking place in the environment, and such self-generated mental activity poses a specific set of challenges for its scientific analysis in both cognitive science and neuroscience. One problem is that the spontaneous onset of self-generated mental activity makes it hard to distinguish the events…

  6. Weld region corrosion during chemical cleaning of PWR [pressurized-water reactor] steam generators: Volume 2, Tests and analyses: Final report

    International Nuclear Information System (INIS)

    Barna, J.L.; Bozeka, S.A.; Jevec, J.M.

    1987-07-01

    The potential for preferential corrosion of steam generator weld regions during chemical cleaning using the generic SGOG solvents was investigated. The investigations included development and use of a corrosion assessment test facility which measured corrosion currents in a realistic model of the steam generator geometry in the vicinity of a specific weld during a simulated chemical dissolution of sludge consisting of essentially pure magnetite. A corrosion monitoring technique was developed and qualified. In this technique free corrosion rates measured by linear polarization techniques are added to corrosion rates calculated from galvanic current measured using a zero resistance ammeter to give an estimate of total corrosion rate for a galvanically corroding material. An analytic modeling technique was developed and proved useful in determining the size requirements for the weld region mockup used in the corrosion assessment test facility. The technique predicted galvanic corrosion rates consistent with that observed in a corrosion assessement test when polarization data used as model input were obtained on-line during the test. The test results obtained during this investigation indicated that chemical cleaning using the SGOG magnetite dissolution solvent can be performed with a small amount of corrosion of secondary side internals and pressure boundary welds. The maximum weld region corrosion measured during a typical chemical cleaning cycle to remove essentially pure magnetite sludge was about 8 mils. However, additional site specific weld region corrosion assessment testing and qualification will be required prior to chemical cleaning steam generators at a specific plant. Recommendations for site specific qualification of chemical cleaning processes and for use of process monitors and on-line corrosion instrumentation are included in this report

  7. Time-Elastic Generative Model for Acceleration Time Series in Human Activity Recognition

    Directory of Open Access Journals (Sweden)

    Mario Munoz-Organero

    2017-02-01

    Full Text Available Body-worn sensors in general and accelerometers in particular have been widely used in order to detect human movements and activities. The execution of each type of movement by each particular individual generates sequences of time series of sensed data from which specific movement related patterns can be assessed. Several machine learning algorithms have been used over windowed segments of sensed data in order to detect such patterns in activity recognition based on intermediate features (either hand-crafted or automatically learned from data. The underlying assumption is that the computed features will capture statistical differences that can properly classify different movements and activities after a training phase based on sensed data. In order to achieve high accuracy and recall rates (and guarantee the generalization of the system to new users, the training data have to contain enough information to characterize all possible ways of executing the activity or movement to be detected. This could imply large amounts of data and a complex and time-consuming training phase, which has been shown to be even more relevant when automatically learning the optimal features to be used. In this paper, we present a novel generative model that is able to generate sequences of time series for characterizing a particular movement based on the time elasticity properties of the sensed data. The model is used to train a stack of auto-encoders in order to learn the particular features able to detect human movements. The results of movement detection using a newly generated database with information on five users performing six different movements are presented. The generalization of results using an existing database is also presented in the paper. The results show that the proposed mechanism is able to obtain acceptable recognition rates (F = 0.77 even in the case of using different people executing a different sequence of movements and using different

  8. The regional electricity generation mix in Scotland: A portfolio selection approach incorporating marine technologies

    International Nuclear Information System (INIS)

    Allan, Grant; Eromenko, Igor; McGregor, Peter; Swales, Kim

    2011-01-01

    Standalone levelised cost assessments of electricity supply options miss an important contribution that renewable and non-fossil fuel technologies can make to the electricity portfolio: that of reducing the variability of electricity costs, and their potentially damaging impact upon economic activity. Portfolio theory applications to the electricity generation mix have shown that renewable technologies, their costs being largely uncorrelated with non-renewable technologies, can offer such benefits. We look at the existing Scottish generation mix and examine drivers of changes out to 2020. We assess recent scenarios for the Scottish generation mix in 2020 against mean-variance efficient portfolios of electricity-generating technologies. Each of the scenarios studied implies a portfolio cost of electricity that is between 22% and 38% higher than the portfolio cost of electricity in 2007. These scenarios prove to be mean-variance 'inefficient' in the sense that, for example, lower variance portfolios can be obtained without increasing portfolio costs, typically by expanding the share of renewables. As part of extensive sensitivity analysis, we find that Wave and Tidal technologies can contribute to lower risk electricity portfolios, while not increasing portfolio cost. - Research Highlights: → Portfolio analysis of scenarios for Scotland's electricity generating mix in 2020. → Reveals potential inefficiencies of selecting mixes based on levelised cost alone. → Portfolio risk-reducing contribution of Wave and Tidal technologies assessed.

  9. The regional electricity generation mix in Scotland: A portfolio selection approach incorporating marine technologies

    Energy Technology Data Exchange (ETDEWEB)

    Allan, Grant, E-mail: grant.j.allan@strath.ac.u [Fraser of Allander Institute, Department of Economics, University of Strathclyde, Sir William Duncan Building, 130 Rottenrow, Glasgow G4 0GE (United Kingdom); Eromenko, Igor; McGregor, Peter [Fraser of Allander Institute, Department of Economics, University of Strathclyde, Sir William Duncan Building, 130 Rottenrow, Glasgow G4 0GE (United Kingdom); Swales, Kim [Department of Economics, University of Strathclyde, Sir William Duncan Building, 130 Rottenrow, Glasgow G4 0GE (United Kingdom)

    2011-01-15

    Standalone levelised cost assessments of electricity supply options miss an important contribution that renewable and non-fossil fuel technologies can make to the electricity portfolio: that of reducing the variability of electricity costs, and their potentially damaging impact upon economic activity. Portfolio theory applications to the electricity generation mix have shown that renewable technologies, their costs being largely uncorrelated with non-renewable technologies, can offer such benefits. We look at the existing Scottish generation mix and examine drivers of changes out to 2020. We assess recent scenarios for the Scottish generation mix in 2020 against mean-variance efficient portfolios of electricity-generating technologies. Each of the scenarios studied implies a portfolio cost of electricity that is between 22% and 38% higher than the portfolio cost of electricity in 2007. These scenarios prove to be mean-variance 'inefficient' in the sense that, for example, lower variance portfolios can be obtained without increasing portfolio costs, typically by expanding the share of renewables. As part of extensive sensitivity analysis, we find that Wave and Tidal technologies can contribute to lower risk electricity portfolios, while not increasing portfolio cost. - Research Highlights: {yields} Portfolio analysis of scenarios for Scotland's electricity generating mix in 2020. {yields} Reveals potential inefficiencies of selecting mixes based on levelised cost alone. {yields} Portfolio risk-reducing contribution of Wave and Tidal technologies assessed.

  10. Active acoustic leak detection in steam generator units of fast reactors

    International Nuclear Information System (INIS)

    Oriol, L.; Journeau, Ch.

    1996-01-01

    Steam generators (SG) of Fast Reactors can be subject to water leakage into the sodium secondary circuit, causing an exothermic chemical reaction with potential serious damage to plant. Within the framework of the European Fast Reactor project, the CEA has developed an active acoustic detection technique which, when used in parallel with passive acoustic detection, will lead to effective leak detection results in terms of reliability and false alarm rates. Whilst the passive method is based on the increase in acoustic noise generated by the reaction, the active method takes advantage of the acoustic attenuation by the hydrogen bubbles produced. The method has been validated: in water, during laboratory testing at the Centre d'Etudes de Cadarache; in sodium, at the ASB loop at Bensberg (Germany) and at AEA Dounreay (Scotland). Full analysis of the tests carried out on the SG of the Prototype Fast Reactor in 1994 during end-of-life testing should lead to reactor validation on the method. (authors)

  11. Complex active regions as the main source of extreme and large solar proton events

    Science.gov (United States)

    Ishkov, V. N.

    2013-12-01

    A study of solar proton sources indicated that solar flare events responsible for ≥2000 pfu proton fluxes mostly occur in complex active regions (CARs), i.e., in transition structures between active regions and activity complexes. Different classes of similar structures and their relation to solar proton events (SPEs) and evolution, depending on the origination conditions, are considered. Arguments in favor of the fact that sunspot groups with extreme dimensions are CARs are presented. An analysis of the flare activity in a CAR resulted in the detection of "physical" boundaries, which separate magnetic structures of the same polarity and are responsible for the independent development of each structure.

  12. Magnetic Energy and Helicity in Two Emerging Active Regions in the Sun

    Science.gov (United States)

    Liu, Y.; Schuck, P. W.

    2012-01-01

    The magnetic energy and relative magnetic helicity in two emerging solar active regions, AR 11072 and AR 11158,are studied. They are computed by integrating over time the energy and relative helicity fluxes across the photosphere. The fluxes consist of two components: one from photospheric tangential flows that shear and braid field lines (shear term), the other from normal flows that advect magnetic flux into the corona (emergence term). For these active regions: (1) relative magnetic helicity in the active-region corona is mainly contributed by the shear term,(2) helicity fluxes from the emergence and the shear terms have the same sign, (3) magnetic energy in the corona (including both potential energy and free energy) is mainly contributed by the emergence term, and(4) energy fluxes from the emergence term and the shear term evolved consistently in phase during the entire flux emergence course.We also examine the apparent tangential velocity derived by tracking field-line footpoints using a simple tracking method. It is found that this velocity is more consistent with tangential plasma velocity than with the flux transport velocity, which agrees with the conclusion by Schuck.

  13. Generation and management of solid waste resulting from tourist activities of the Porto de Galinhas - P

    Directory of Open Access Journals (Sweden)

    Jaqueline Guimarães Santos

    2015-04-01

    Full Text Available The significant solid waste generation, coupled with the lack of proper management of the waste generated, has been one of the issues of concern and conducting research on the part of scholars in the field. Tourism as an activity that positively impacts and negativity a given location, has emerged as an activity that can generate a lot of waste, especially in periods of high season, considering the increase of people moving to the tourist destinations. Accordingly, this study aims to analyze the generation and management of solid waste resulting from tourism in Porto de Galinhas, PE. We performed an exploratory, descriptive, qualitative study, conducted in the form of a case study in Porto de Galinhas, PE. The data collection was done interviews together social actors, as well as non-participant observation during data collection. The results showed that tourism activities in Porto de Galinhas result in a high amount of solid waste, and these are directed to inappropriate places. Although fate presents a combination of recyclable materials, RECYCLE, reuses this not a significant amount, given the proportion of waste generated.

  14. Forward modeling transient brightenings and microflares around an active region observed with Hi-C

    Energy Technology Data Exchange (ETDEWEB)

    Kobelski, Adam R. [Now at National Radio Astronomy Observatory, P.O. Box 2, Green Bank, WV 24944 (United States); McKenzie, David E., E-mail: kobelski@solar.physics.montana.edu [Department of Physics, P.O. Box 173840, Montana State University, Bozeman, MT 59717-3840 (United States)

    2014-10-20

    Small-scale flare-like brightenings around active regions are among the smallest and most fundamental of energetic transient events in the corona, providing a testbed for models of heating and active region dynamics. In a previous study, we modeled a large collection of these microflares observed with Hinode/X-Ray Telescope (XRT) using EBTEL and found that they required multiple heating events, but could not distinguish between multiple heating events on a single strand, or multiple strands each experiencing a single heating event. We present here a similar study, but with extreme-ultraviolet data of Active Region 11520 from the High Resolution Coronal Imager (Hi-C) sounding rocket. Hi-C provides an order of magnitude improvement to the spatial resolution of XRT, and a cooler temperature sensitivity, which combine to provide significant improvements to our ability to detect and model microflare activity around active regions. We have found that at the spatial resolution of Hi-C (≈0.''3), the events occur much more frequently than expected (57 events detected, only 1 or 2 expected), and are most likely made from strands of the order of 100 km wide, each of which is impulsively heated with multiple heating events. These findings tend to support bursty reconnection as the cause of the energy release responsible for the brightenings.

  15. Electricity generation from wetlands with activated carbon bioanode

    Science.gov (United States)

    Sudirjo, E.; Buisman, C. J. N.; Strik, D. P. B. T. B.

    2018-03-01

    Paddy fields are potential non-tidal wetlands to apply Plant Microbial Fuel Cell (PMFC) technology. World widely they cover about 160 million ha of which 13.3 million ha is located in Indonesia. With the PMFC, in-situ electricity is generated by a bioanode with electrochemically active bacteria which use primary the organic matter supplied by the plant (e.g. as rhizodeposits and plant residues). One of limitations when installing a PMFC in a non-tidal wetland is the usage of “expensive” large amounts of electrodes to overcome the poor conductivity of wet soils. However, in a cultivated wetland such as rice paddy field, it is possible to alter soil composition. Adding a conductive carbon material such as activated carbon is believed to improve soil conductivity with minimum impact on plant vitality. The objective of this research was to study the effect of activated carbon as an alternative bioanode material on the electricity output and plants vitality. Lab result shows that activated carbon can be a potential alternative for bioanode material. It can continuously deliver current on average 1.54 A/m3 anode (0.26 A/m2 PGA or 66 mW/m2 PGA) for 98 days. Based on this result the next step is to do a test of this technology in the real paddy fields.

  16. Identification and characterization of a highly variable region in mitochondrial genomes of fusarium species and analysis of power generation from microbial fuel cells

    Science.gov (United States)

    Hamzah, Haider Mousa

    In the microbial fuel cell (MFC) project, power generation from Shewanella oneidensis MR-1 was analyzed looking for a novel system for both energy generation and sustainability. The results suggest the possibility of generating electricity from different organic substances, which include agricultural and industrial by-products. Shewanella oneidensis MR-1 generates usable electrons at 30°C using both submerged and solid state cultures. In the MFC biocathode experiment, most of the CO2 generated at the anodic chamber was converted into bicarbonate due the activity of carbonic anhydrase (CA) of the Gluconobacter sp.33 strain. These findings demonstrate the possibility of generation of electricity while at the same time allowing the biomimetic sequestration of CO2 using bacterial CA. In the mitochondrial genomes project, the filamentous fungal species Fusarium oxysporum was used as a model. This species causes wilt of several important agricultural crops. A previous study revealed that a highly variable region (HVR) in the mitochondrial DNA (mtDNA) of three species of Fusarium contained a large, variable unidentified open reading frame (LV-uORF). Using specific primers for two regions of the LV-uORF, six strains were found to contain the ORF by PCR and database searches identified 18 other strains outside of the Fusarium oxysporum species complex. The LV-uORF was also identified in three isolates of the F. oxysporum species complex. Interestingly, several F. oxysporum isolates lack the LV-uORF and instead contain 13 ORFs in the HVR, nine of which are unidentified. The high GC content and codon usage of the LV-uORF indicate that it did not co-evolve with other mt genes and was horizontally acquired and was introduced to the Fusarium lineage prior to speciation. The nonsynonymous/synonymous (dN/dS) ratio of the LV-uORFs (0.43) suggests it is under purifying selection and the putative polypeptide is predicted to be located in the mitochondrial membrane. Growth assays

  17. The analytical approach to optimization of active region structure of quantum dot laser

    International Nuclear Information System (INIS)

    Korenev, V V; Savelyev, A V; Zhukov, A E; Omelchenko, A V; Maximov, M V

    2014-01-01

    Using the analytical approach introduced in our previous papers we analyse the possibilities of optimization of size and structure of active region of semiconductor quantum dot lasers emitting via ground-state optical transitions. It is shown that there are optimal length' dispersion and number of QD layers in laser active region which allow one to obtain lasing spectrum of a given width at minimum injection current. Laser efficiency corresponding to the injection current optimized by the cavity length is practically equal to its maximum value

  18. The analytical approach to optimization of active region structure of quantum dot laser

    Science.gov (United States)

    Korenev, V. V.; Savelyev, A. V.; Zhukov, A. E.; Omelchenko, A. V.; Maximov, M. V.

    2014-10-01

    Using the analytical approach introduced in our previous papers we analyse the possibilities of optimization of size and structure of active region of semiconductor quantum dot lasers emitting via ground-state optical transitions. It is shown that there are optimal length' dispersion and number of QD layers in laser active region which allow one to obtain lasing spectrum of a given width at minimum injection current. Laser efficiency corresponding to the injection current optimized by the cavity length is practically equal to its maximum value.

  19. Exploring Preferences of Mentoring Activities among Generational Groups of Registered Nurses in Florida

    Science.gov (United States)

    Posey-Goodwin, Patricia Ann

    2013-01-01

    The purpose of this study was to explore differences in perceptions of mentoring activities from four generations of registered nurses in Florida, using the Alleman Mentoring Activities Questionnaire ® (AMAQ ®). Statistical procedures of analysis of variance (ANOVA) were employed to explore differences among 65 registered nurses in Florida from…

  20. Does selection against transcriptional interference shape retroelement-free regions in mammalian genomes?

    Directory of Open Access Journals (Sweden)

    Tobias Mourier

    Full Text Available BACKGROUND: Eukaryotic genomes are scattered with retroelements that proliferate through retrotransposition. Although retroelements make up around 40 percent of the human genome, large regions are found to be completely devoid of retroelements. This has been hypothesised to be a result of genomic regions being intolerant to insertions of retroelements. The inadvertent transcriptional activity of retroelements may affect neighbouring genes, which in turn could be detrimental to an organism. We speculate that such retroelement transcription, or transcriptional interference, is a contributing factor in generating and maintaining retroelement-free regions in the human genome. METHODOLOGY/PRINCIPAL FINDINGS: Based on the known transcriptional properties of retroelements, we expect long interspersed elements (LINEs to be able to display a high degree of transcriptional interference. In contrast, we expect short interspersed elements (SINEs to display very low levels of transcriptional interference. We find that genomic regions devoid of long interspersed elements (LINEs are enriched for protein-coding genes, but that this is not the case for regions devoid of short interspersed elements (SINEs. This is expected if genes are subject to selection against transcriptional interference. We do not find microRNAs to be associated with genomic regions devoid of either SINEs or LINEs. We further observe an increased relative activity of genes overlapping LINE-free regions during early embryogenesis, where activity of LINEs has been identified previously. CONCLUSIONS/SIGNIFICANCE: Our observations are consistent with the notion that selection against transcriptional interference has contributed to the maintenance and/or generation of retroelement-free regions in the human genome.

  1. Altered spontaneous brain activity in adolescent boys with pure conduct disorder revealed by regional homogeneity analysis.

    Science.gov (United States)

    Wu, Qiong; Zhang, Xiaocui; Dong, Daifeng; Wang, Xiang; Yao, Shuqiao

    2017-07-01

    Functional magnetic resonance imaging (fMRI) studies have revealed abnormal neural activity in several brain regions of adolescents with conduct disorder (CD) performing various tasks. However, little is known about the spontaneous neural activity in people with CD in a resting state. The aims of this study were to investigate CD-associated regional activity abnormalities and to explore the relationship between behavioral impulsivity and regional activity abnormalities. Resting-state fMRI (rs-fMRI) scans were administered to 28 adolescents with CD and 28 age-, gender-, and IQ-matched healthy controls (HCs). The rs-fMRI data were subjected to regional homogeneity (ReHo) analysis. ReHo can demonstrate the temporal synchrony of regional blood oxygen level-dependent signals and reflect the coordination of local neuronal activity facilitating similar goals or representations. Compared to HCs, the CD group showed increased ReHo bilaterally in the insula as well as decreased ReHo in the right inferior parietal lobule, right middle temporal gyrus and right fusiform gyrus, left anterior cerebellum anterior, and right posterior cerebellum. In the CD group, mean ReHo values in the left and the right insula correlated positively with Barratt Impulsivity Scale (BIS) total scores. The results suggest that CD is associated with abnormal intrinsic brain activity, mainly in the cerebellum and temporal-parietal-limbic cortices, regions that are related to emotional and cognitive processing. BIS scores in adolescents with CD may reflect severity of abnormal neuronal synchronization in the insula.

  2. Generation of 3D templates of active sites of proteins with rigid prosthetic groups.

    Science.gov (United States)

    Nebel, Jean-Christophe

    2006-05-15

    With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein structures is an exciting prospect: active sites could be better understood, protein functions and protein 3D structures could be predicted more accurately. Although patterns can already be generated at the fold and topological levels, no system produces high-resolution 3D patterns including atom and cavity positions. To address this challenge, our research focuses on generating patterns from proteins with rigid prosthetic groups. Since these groups are key elements of protein active sites, the generated 3D patterns are expected to be biologically meaningful. In this paper, we present a new approach which allows the generation of 3D patterns from proteins with rigid prosthetic groups. Using 237 protein chains representing proteins containing porphyrin rings, our method was validated by comparing 3D templates generated from homologues with the 3D structure of the proteins they model. Atom positions were predicted reliably: 93% of them had an accuracy of 1.00 A or less. Moreover, similar results were obtained regarding chemical group and cavity positions. Results also suggested our system could contribute to the validation of 3D protein models. Finally, a 3D template was generated for the active site of human cytochrome P450 CYP17, the 3D structure of which is unknown. Its analysis showed that it is biologically meaningful: our method detected the main patterns of the cytochrome P450 superfamily and the motifs linked to catalytic reactions. The 3D template also suggested the position of a residue, which could be involved in a hydrogen bond with CYP17 substrates and the shape and location of a cavity. Comparisons with independently generated 3D models comforted these hypotheses. Alignment software (Nestor3D) is available at http://www.kingston.ac.uk/~ku33185/Nestor3D.html

  3. Entrepreneurial activity and regional development: an introduction to this special issue

    Directory of Open Access Journals (Sweden)

    Maribel Guerrero

    2013-01-01

    Full Text Available The main objective of this special issue is to analyze the relationship between entrepreneurial intention and entrepreneurial activity and its impact on regional development. The last convulsive decade, with expansionary and recessionary economic cycles, offers a good opportunity to study how economic cycles affect the propensity of becoming an entrepreneur and, in turn, to observe how entrepreneurial activity contributes to change (improvement in the economy.Previous studies have analyzed the complicated endogenous relationship between entrepreneurship and economic growth, but these studies have examined the countries’ performance under a static view. This special issue focuses on analyzing complex entrepreneurial behavior from a sub-national perspective (examining several regions in the Spanish autonomous communities and a dynamic view (using data from several years, which adds rigor and valuable knowledge to this research field.

  4. Pulsed neutron generator for mass flow measurement using the pulsed neutron activation technique

    International Nuclear Information System (INIS)

    Rochau, G.E.; Hornsby, D.R.; Mareda, J.F.; Riggan, W.C.

    1980-01-01

    A high-output, transportable neutron generator has been developed to measure mass flow velocities in reactor safety tests using the Pulsed Neutron Activation (PNA) Technique. The PNA generator produces >10 10 14 MeV D-T neutrons in a 1.2 millisecond pulse. The Millisecond Pulse (MSP) Neutron Tube, developed for this application, has an expected operational life of 1000 pulses, and it limits the generator pulse repetition rate to 12 pulses/minute. A semiconductor neutron detector is included in the generator package to monitor the neutron output. The control unit, which can be operated manually or remotely, also contains a digital display with a BCD output for the neutron monitor information. The digital logic of the unit controls the safety interlocks and rejects transient signals which could accidently fire the generator

  5. The transcriptionally active regions in the genome of Bacillus subtilis

    DEFF Research Database (Denmark)

    Rasmussen, Simon; Nielsen, Henrik Bjørn; Jarmer, Hanne Østergaard

    2009-01-01

    The majority of all genes have so far been identified and annotated systematically through in silico gene finding. Here we report the finding of 3662 strand-specific transcriptionally active regions (TARs) in the genome of Bacillus subtilis by the use of tiling arrays. We have measured the genome...

  6. Magnetic and Velocity Field Variations in the Active Regions NOAA ...

    Indian Academy of Sciences (India)

    Abstract. We study the magnetic and velocity field evolution in the two magnetically complex active regions NOAA 10486 and NOAA 10488 observed during October–November 2003. We have used the available data to examine net flux and Doppler velocity time profiles to identify changes associated with evolutionary and ...

  7. How shall we hand over the atomic energy to the next generation? Publicity activities to the youth

    International Nuclear Information System (INIS)

    Kudo, Kazuhiko; Kaji, Yoshiyuki; Kumagaya, Akira; Shibata, Toshikazu; Watanabe, Tamaki; Murakami, Masatoshi; Nishina, Kojiro.

    1995-01-01

    It is important for Atomic Energy Society of Japan which covers the wide fields related to atomic energy to know exactly what the youths who bear the next generation learn about atomic energy and what feeling they have. However, the attitude or the attempt of meeting young generation from such viewpoint was not sufficient so far. In the phenomena of 'away from atomic energy' recently pointed out frequently, the root seems to have existed long ago. In this feature article, from such critical mind, the present status and the plan for hereafter of atomic energy publicity activities for young generation and those concerned to education are made clear. The publicity activities for school education and young generation, the publicity activities for those concerned to education, the questionnaire of the consciousness about energy and environment, the open school activity of Atomic Energy Society of Japan, the nuclear reactor experiment and study for middle and high school teachers, the assembling of simplified GM counters and the experiment of measuring radiation, the activities of Plasnet for young generation and the exercise and seminar on radiation for high school students are reported. Japanese social system is at the root of atomic energy problem, and the effort to improve it contributes to innovate the constitution of whole Japan. (K.I.)

  8. Embalse steam generators - status in 2009

    International Nuclear Information System (INIS)

    Luna, P.; Yetisir, M.; Roy, S.; MacEacheron, R.

    2009-01-01

    The Embalse Nuclear Generating Station (ENGS) is a CANDU 6, a pressurized heavy water plant, with a net capacity of 648 MW. The primary heat transport system at Embalse includes four Steam Generators (SGs) manufactured by Babcock and Wilcox Canada (B and W). These steam generators are vertical recirculating heat exchangers with Incoloy 800 inverted U-tubes and an integral preheater. Embalse SGs performed very well until the late 1990s, when an increase in tube fretting was noticed in the U-bend region. In-service inspection in 2002 and 2004 confirmed that the cause of the tube fretting was flow accelerated corrosion (FAC) damage of scallop bar supports in the U-bend region. The straight leg tube support plates (TSPs) have also been degrading. Degradation was worst at the top support plates, and it was in the form of material loss on the cold leg. The hot leg TSPs were heavily fouled with deposits and flow areas were blocked. Visual inspections and subsequent studies showed that the cause of the TSP degradation was also FAC. The Embalse SGs have carbon steel supports that make them susceptible to FAC. To mitigate the effects of degraded tube support structures, three additional sets of anti-vibration bars were installed in the U-bend regions of all four steam generators in 2004. In 2007, an improved secondary-side chemistry specification was implemented to reduce the FAC rate and the hot leg TSPs was waterlanced. A root cause analysis and condition assessment was performed for the tube supports in 2007. Fitness for Service (FFS) evaluation was completed using the Canadian Industry Guidelines for steam generator tubes. The steam generators were returned to service and the plan has operated without another forced outage to date. The FAC degradation of the carbon steel U-bend tube support systems has had the most significant impact on the plant operation causing a number of forced outages. The discovery of the extent of TSP degradation and difficulties to repair TSPs

  9. Magnetic structure of an activated filament in a flaring active region

    Science.gov (United States)

    Sasso, C.; Lagg, A.; Solanki, S. K.

    2014-01-01

    Aims: While the magnetic field in quiescent prominences has been widely investigated, less is known about the field in activated prominences. We report observational results on the magnetic field structure of an activated filament in a flaring active region. In particular, we studied its magnetic structure and line-of-sight flows during its early activated phase, shortly before it displayed signs of rotation. Methods: We inverted the Stokes profiles of the chromospheric He i 10 830 Å triplet and the photospheric Si i 10 827 Å line observed in this filament by the Vacuum Tower Telescope on Tenerife. Using these inversion results, we present and interpret the first maps of the velocity and magnetic field obtained in an activated filament, both in the photosphere and the chromosphere. Results: Up to five different magnetic components are found in the chromospheric layers of the filament, while outside the filament a single component is sufficient to reproduce the observations. Magnetic components displaying an upflow are preferentially located towards the centre of the filament, while the downflows are concentrated along its periphery. Moreover, the upflowing gas is associated with an opposite-polarity magnetic configuration with respect to the photosphere, while the downflowing gas is associated with a same-polarity configuration. Conclusions: The activated filament has a very complex structure. Nonetheless, it is compatible with a flux rope, albeit a distorted one, in the normal configuration. The observations are best explained by a rising flux rope in which part of the filament material is still stably stored (upflowing material, rising with the field), while the rest is no longer stably stored and flows down along the field lines. The movie is available in electronic form at http://www.aanda.org

  10. Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.

    Science.gov (United States)

    Kikuchi, Hidehiko; Mimuro, Hitomi; Kuribayashi, Futoshi

    2018-01-01

    The membrane bound cytochrome b 558 composed of gp91-phox and p22-phox proteins, and cytosolic proteins p40-, p47-and p67-phox are important components of superoxide (O 2 - )-generating system in phagocytes. Here, we describe that resveratrol, a pleiotropic phytochemical belonging to the stilbenoids, dramatically activates the O 2 - -generating system during retinoic acid (RA)-induced differentiation of human monoblastic leukemia U937 cells to macrophage-like cells. When U937 cells were cultured in the presence of RA and resveratrol, the O 2 - -generating activity increased more than 5-fold compared with that in the absence of the latter. Semiquantitative RT-PCR showed that co-treatment with RA and resveratrol strongly enhanced transcription of the gp91-phox compared with those of the RA-treatment only. On the other hand, immunoblot analysis revealed that co-treatment with RA and resveratrol caused remarkable accumulation of protein levels of gp91-phox (to 4-fold), p22-phox (to 5-fold) and p47-phox (to 4-fold) compared with those of the RA-treatment alone. In addition, ChIP assay suggested that resveratrol participates in enhancing the gene expression of gp91-phox via promoting acetylation of Lys-9 residues and Lys-14 residues of histone H3 within chromatin around the promoter regions of the gene. These results suggested that resveratrol strongly enhances the RA-induced O 2 - -generating activity via up-regulation of gp91-phox gene expression in U937 cells. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Pick up of cesium and cobalt activity by oxide sludge in steam generator

    International Nuclear Information System (INIS)

    Rufus, A.L.; Subramanian, H.; Velmurugan, S.; Santanu Bera; Narasimhan, S.V.; Reddy, G.L.N.; Sankara Sastry, V.

    2002-01-01

    A pinhole developed near the tube sheet in the steam generator (SG) tube of a pressurised heavy water reactor (PHWR) caused leak of primary coolant containing radioactive contaminants ( 137 Cs, 134 Cs and 60 Co) to the shell side. The sludge collected from the tube sheet region was found to have adsorbed these radionuclides at the high temperature (230-240 deg C) that prevailed in the SG. An attempt has been made to evaluate the quantity of activity retained in the various oxide phases that constitute the sludge and their mode of pick-up. The sludge was characterized by XRD and XPS, which showed the presence of various oxides of iron, copper and nickel along with the silicates of calcium, magnesium and aluminium. Gamma-spectrometry of the sludge confirmed the presence of 137 Cs, 134 Cs and 60 Co to an extent of 7.6, 1.3 and 0.9 μCi/g of sludge, respectively. Selective dissolution in various EDTA based formulations and equilibration with nitric acid and magnesium chloride solutions helped to understand the quantity of activity adsorbed by various constituents of the sludge. It was concluded that a major portion of cesium was picked up by a reversible ion exchange process on various oxide constituents and about 10% by an irreversible specific adsorption process on insoluble silicates. Also, it was proved that 60 Co was specifically adsorbed over the oxides of iron and nickel. (author)

  12. Acoustic holograms of active regions

    International Nuclear Information System (INIS)

    Chou, Dean-Yi

    2008-01-01

    We propose a method to study solar magnetic regions in the solar interior with the principle of optical holography. A magnetic region in the solar interior scatters the solar background acoustic waves. The scattered waves and background waves could form an interference pattern on the solar surface. We investigate the feasibility of detecting this interference pattern on the solar surface, and using it to construct the three-dimensional scattered wave from the magnetic region with the principle of optical holography. In solar acoustic holography, the background acoustic waves play the role of reference wave; the magnetic region plays the role of the target object; the interference pattern, acoustic power map, on the solar surface plays the role of the hologram.

  13. Acoustic holograms of active regions

    Energy Technology Data Exchange (ETDEWEB)

    Chou, Dean-Yi [Physics Department, National Tsing Hua University, Hsinchu, 30013, Taiwan (China)], E-mail: chou@phys.nthu.edu.tw

    2008-10-15

    We propose a method to study solar magnetic regions in the solar interior with the principle of optical holography. A magnetic region in the solar interior scatters the solar background acoustic waves. The scattered waves and background waves could form an interference pattern on the solar surface. We investigate the feasibility of detecting this interference pattern on the solar surface, and using it to construct the three-dimensional scattered wave from the magnetic region with the principle of optical holography. In solar acoustic holography, the background acoustic waves play the role of reference wave; the magnetic region plays the role of the target object; the interference pattern, acoustic power map, on the solar surface plays the role of the hologram.

  14. Southeast Regional Assessment Study: an assessment of the opportunities of solar electric power generation in the Southeastern United States

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-07-01

    The objective of this study was to identify and assess opportunities for demonstration and large scale deployment of solar electric facilities in the southeast region and to define the technical, economic, and institutional factors that can contribute to an accelerated use of solar energy for electric power generation. Graphs and tables are presented indicating the solar resource potential, siting opportunities, energy generation and use, and socioeconomic factors of the region by state. Solar electric technologies considered include both central station and dispersed solar electric generating facilities. Central stations studied include solar thermal electric, wind, photovoltaic, ocean thermal gradient, and biomass; dispersed facilities include solar thermal total energy systems, wind, and photovoltaic. The value of solar electric facilities is determined in terms of the value of conventional facilities and the use of conventional fuels which the solar facilities can replace. Suitable cost and risk sharing mechanisms to accelerate the commercialization of solar electric technologies in the Southeast are identified. The major regulatory and legal factors which could impact on the commercialization of solar facilities are reviewed. The most important factors which affect market penetration are reviewed, ways to accelerate the implementation of these technologies are identified, and market entry paths are identified. Conclusions and recommendations are presented. (WHK)

  15. Results of the IRIS UV Burst Survey, Part I: Active Regions Tracked Limb to Limb

    Science.gov (United States)

    Madsen, C. A.; DeLuca, E.

    2017-12-01

    We present results from the first phase of an effort to thoroughly characterize UV bursts within the Interface Region Imaging Spectrograph (IRIS) data catalogue. The observational signatures of these phenomena include dramatically intensified and broadened NUV/FUV emission line profiles with absorption features from cool metallic ions. These properties suggest that UV bursts originate from plasma at transition region temperatures (≥ 80,000 K) which is deeply embedded in the cool lower chromosphere ( 5,000 K). Rigorously characterizing the energetic and dynamical properties of UV bursts is crucial since they have considerable potential to heat active region chromospheres and could provide critical constraints for models of magnetic reconnection in these regions. The survey first focuses on IRIS observations of active regions tracked from limb to limb. All observations consist of large field-of-view raster scans of 320 or 400 steps each, which allow for widespread detection of many burst profiles at the expense of having limited short-term time evolution information. We detect bursts efficiently by applying a semi-automated single-Gaussian fitting technique to Si IV 1393.8 Å emission profiles that isolates the distinct burst population in a 4-D parameter space. The robust sample of NUV/FUV burst spectra allows for precise constraints of properties critical for modeling reconnection in the chromosphere, including outflow kinetic energy, density estimates from intensity ratios of Si IV 1402.8 Å and O IV 1401.2 Å emission lines, and coincident measures of emission in other wavelengths. We also track burst properties throughout the lifetimes of their host active regions, noting changes in detection rate and preferential location as the active regions evolve. Finally, the tracked active region observations provide a unique opportunity to investigate line-of-sight effects on observed UV burst spectral properties, particularly the strength of Ni II 1393.3 Å absorption

  16. Physics of the Solar Active Regions from Radio Observations

    Science.gov (United States)

    Gelfreikh, G. B.

    1999-12-01

    Localized increase of the magnetic field observed by routine methods on the photosphere result in the growth of a number of active processes in the solar atmosphere and the heliosphere. These localized regions of increased magnetic field are called active regions (AR). The main processes of transfer, accumulation and release of energy in an AR is, however, out of scope of photospheric observations being essentially a 3D-process and happening either under photosphere or up in the corona. So, to investigate these plasma structures and processes we are bound to use either extrapolation of optical observational methods or observations in EUV, X-rays and radio. In this review, we stress and illustrate the input to the problem gained from radio astronomical methods and discuss possible future development of their applicatications. Historically speaking each new step in developing radio technique of observations resulted in detecting some new physics of ARs. The most significant progress in the last few years in radio diagnostics of the plasma structures of magnetospheres of the solar ARs is connected with the developing of the 2D full disk analysis on regular basis made at Nobeyama and detailed multichannel spectral-polarization (but one-dimensional and one per day) solar observations at the RATAN-600. In this report the bulk of attention is paid to the new approach to the study of solar activity gained with the Nobeyama radioheliograph and analyzing the ways for future progress. The most important new features of the multicomponent radio sources of the ARs studied using Nobeyama radioheliograph are as follow: 1. The analysis of magnetic field structures in solar corona above sunspot with 2000 G. Their temporal evolution and fluctuations with the periods around 3 and 5 minutes, due to MHD-waves in sunspot magnetic tubes and surrounding plasma. These investigations are certainly based on an analysis of thermal cyclotron emission of lower corona and CCTR above sunspot

  17. Determination of 137Cs activities in soil samples from east and south Marmara region, Turkey

    International Nuclear Information System (INIS)

    Kilic, Oe.; Belivermis, M.; Cotuk, Y.; Coskun, M.; Cayir, A.; Kuecer, R.

    2006-01-01

    Activity concentrations of 1 37Cs, 4 0K and physico-chemical parameters of soil samples collected from 99 sampling stations in the east and south of Marmara Region of Turkey were determined. The study region was divided into 20 x 20 km grids and soil samples collected randomly in each square from 0-5 cm surface layer. Activities were measured by means of multichannel gamma analyser provided with high purity germanium detector. Relations among 1 37Cs concentrations and physico-chemical parameters of soils and climatic factors of the region were evaluated. Arc View GIS version 3.1 was used mapping of study area. Distribution of radionuclide concentrations in the region illustrated with contour maps using Surfer 8.0 for Windows. The range of activity concentrations of 1 37Cs and 4 0K were measured to be 0.92-153.72 and 69.24-1085.57 Bq/kg respectively

  18. Measurement of Mo-99 column activity in the evaluation of Mo-99/Tc-99m generator

    International Nuclear Information System (INIS)

    Kuster, Z.

    1994-01-01

    In order to calculate the real elution efficiency of Mo-99/Tc-99m generator the Mo-99 content on the column has to be previously determined. As found in this work, the external measurement of Mo-99-column activity by means of Geiger-Mueller counter is a simple, fast and reliable method. Generally, Mo-99-column is placed slightly out of the center of the generator; therefore the externally measured flux of photons (φ) is an angular-dependent function. If the thickness of the lead container is radially uniform, the flux measured at some distance from the generator (which is rotated in 2π/3 steps) is given by the equation φ = A (1 + Bcos (α-2π(i - 2)/3)) -1 , i=1,2 or 3 (Eq.1) where A is a numerical constant depending on the Mo-99-column activity, B is a numerical constant depending on the Mo-99- column position within the lead container, the angle α depends on the initial orientation of the generator. A total of 20 generator were studied. The measured Mo-99-column activities (Capintec dose calibrator) were in the range 13.1- 35.11 GBq. Contrary to the findings of Vinberg and Kristensen (Eur J Nucl Med 1/1976(219), values of A (Eq. 1) are in good correlation (r 2 =0.9794) with the measured Mo-99-column activities. (author)

  19. The N-terminal, polybasic region is critical for prion protein neuroprotective activity.

    Directory of Open Access Journals (Sweden)

    Jessie A Turnbaugh

    Full Text Available Several lines of evidence suggest that the normal form of the prion protein, PrP(C, exerts a neuroprotective activity against cellular stress or toxicity. One of the clearest examples of such activity is the ability of wild-type PrP(C to suppress the spontaneous neurodegenerative phenotype of transgenic mice expressing a deleted form of PrP (Δ32-134, called F35. To define domains of PrP involved in its neuroprotective activity, we have analyzed the ability of several deletion mutants of PrP (Δ23-31, Δ23-111, and Δ23-134 to rescue the phenotype of Tg(F35 mice. Surprisingly, all of these mutants displayed greatly diminished rescue activity, although Δ23-31 PrP partially suppressed neuronal loss when expressed at very high levels. Our results pinpoint the N-terminal, polybasic domain as a critical determinant of PrP(C neuroprotective activity, and suggest that identification of molecules interacting with this region will provide important clues regarding the normal function of the protein. Small molecule ligands targeting this region may also represent useful therapeutic agents for treatment of prion diseases.

  20. Oil Exploration and Ethnic Militia activities in the Niger Delta Region ...

    African Journals Online (AJOL)

    User

    dominant source of livelihood of the people in the region. The exploration .... ranging from freedom fighting and Nationalism to activities bordering on criminality. This paper .... a kind of private army whose members are enrolled on military lives ...

  1. Dynamics and Control of Lateral Tower Vibrations in Offshore Wind Turbines by Means of Active Generator Torque

    Directory of Open Access Journals (Sweden)

    Zili Zhang

    2014-11-01

    Full Text Available Lateral tower vibrations of offshore wind turbines are normally lightly damped, and large amplitude vibrations induced by wind and wave loads in this direction may significantly shorten the fatigue life of the tower. This paper proposes the modeling and control of lateral tower vibrations in offshore wind turbines using active generator torque. To implement the active control algorithm, both the mechanical and power electronic aspects have been taken into consideration. A 13-degrees-of-freedom aeroelastic wind turbine model with generator and pitch controllers is derived using the Euler–Lagrangian approach. The model displays important features of wind turbines, such as mixed moving frame and fixed frame-defined degrees-of-freedom, couplings of the tower-blade-drivetrain vibrations, as well as aerodynamic damping present in different modes of motions. The load transfer mechanisms from the drivetrain and the generator to the nacelle are derived, and the interaction between the generator torque and the lateral tower vibration are presented in a generalized manner. A three-dimensional rotational sampled turbulence field is generated and applied to the rotor, and the tower is excited by a first order wave load in the lateral direction. Next, a simple active control algorithm is proposed based on active generator torques with feedback from the measured lateral tower vibrations. A full-scale power converter configuration with a cascaded loop control structure is also introduced to produce the feedback control torque in real time. Numerical simulations have been carried out using data calibrated to the referential 5-MW NREL (National Renewable Energy Laboratory offshore wind turbine. Cases of drivetrains with a gearbox and direct drive to the generator are considered using the same time series for the wave and turbulence loadings. Results show that by using active generator torque control, lateral tower vibrations can be significantly mitigated for

  2. Active tectonics and earthquake potential of the Myanmar region

    OpenAIRE

    Wang, Yu; Sieh, Kerry; Tun, Soe Thura; Lai, Kuang-Yin; Myint, Than

    2014-01-01

    This paper describes geomorphologic evidence for the principal neotectonic features of Myanmar and its immediate surroundings. We combine this evidence with published structural, geodetic, and seismic data to present an overview of the active tectonic architecture of the region and its seismic potential. Three tectonic systems accommodate oblique collision of the Indian plate with Southeast Asia and extrusion of Asian territory around the eastern syntaxis of the Himalayan mountain range. Subd...

  3. Flare activity, sunspot motions, and the evolution of vector magnetic fields in Hale region 17244

    Science.gov (United States)

    Neidig, Donald F.; Hagyard, Mona J.; Machado, Marcos E.; Smith, Jesse B., Jr.

    1986-01-01

    The magnetic and dynamical circumstances leading to the 1B/M4 flare of November 5, 1980 are studied, and a strong association is found between the buildup of magnetic shear and the onset of flare activity within the active region. The development of shear, as observed directly in vector magnetograms, is consistent in detail with the dynamical history of the active region and identifies the precise location of the optical and hard-X-ray kernels of the flare emission.

  4. An fMRI study of sex differences in regional activation to a verbal and a spatial task.

    Science.gov (United States)

    Gur, R C; Alsop, D; Glahn, D; Petty, R; Swanson, C L; Maldjian, J A; Turetsky, B I; Detre, J A; Gee, J; Gur, R E

    2000-09-01

    Sex differences in cognitive performance have been documented, women performing better on some phonological tasks and men on spatial tasks. An earlier fMRI study suggested sex differences in distributed brain activation during phonological processing, with bilateral activation seen in women while men showed primarily left-lateralized activation. This blood oxygen level-dependent fMRI study examined sex differences (14 men, 13 women) in activation for a spatial task (judgment of line orientation) compared to a verbal-reasoning task (analogies) that does not typically show sex differences. Task difficulty was manipulated. Hypothesized ROI-based analysis documented the expected left-lateralized changes for the verbal task in the inferior parietal and planum temporal regions in both men and women, but only men showed right-lateralized increase for the spatial task in these regions. Image-based analysis revealed a distributed network of cortical regions activated by the tasks, which consisted of the lateral frontal, medial frontal, mid-temporal, occipitoparietal, and occipital regions. The activation was more left lateralized for the verbal and more right for the spatial tasks, but men also showed some left activation for the spatial task, which was not seen in women. Increased task difficulty produced more distributed activation for the verbal and more circumscribed activation for the spatial task. The results suggest that failure to activate the appropriate hemisphere in regions directly involved in task performance may explain certain sex differences in performance. They also extend, for a spatial task, the principle that bilateral activation in a distributed cognitive system underlies sex differences in performance. Copyright 2000 Academic Press.

  5. 5'-nucleotidase and protein kinase activity of plasmatic membrane and 5'-nucleotidase activity of liver homogenate in the third and fourth rat generations born in the Chernobyl accident zone

    International Nuclear Information System (INIS)

    Bezdrobnij, Yu.V.; Serkyiz, Ya.Yi.; Bozhok, O.V.; Yindik, V.M.

    1994-01-01

    The decrease of plasmatic membrane protein kinase activity of 3 - month rat liver was revealed in animals that have been born and kept in the Chernobyl accident zone during three and four generations. Erythrocyte ghost protein kinase activity from those animals was decreased too. 5'-nucleotidase activity in membranes and in homogenates was increased in the third and decreased in the fourth generation. In 6 month rats of the fourth generation in comparison with 3 month rats of this generation plasmatic membrane protein kinase and 5'-nucleotidase activities did not change but 5'nucleotidase activity of homogenate was increased (to control level). The plasmatic membrane protein kinase activity has been supposed to serve as a bio indicator of ionising irradiation at low dose rate

  6. Inference Generation during Text Comprehension by Adults with Right Hemisphere Brain Damage: Activation Failure Versus Multiple Activation.

    Science.gov (United States)

    Tompkins, Connie A.; Fassbinder, Wiltrud; Blake, Margaret Lehman; Baumgaertner, Annette; Jayaram, Nandini

    2004-01-01

    ourse comprehensionEvidence conflicts as to whether adults with right hemisphere brain damage (RHD) generate inferences during text comprehension. M. Beeman (1993) reported that adults with RHD fail to activate the lexical-semantic bases of routine bridging inferences, which are necessary for comprehension. But other evidence indicates that adults…

  7. Generation and Active Absorption of 2- and 3-Dimensional Linear Water Waves in Physical Models

    DEFF Research Database (Denmark)

    Christensen, Morten

    in the wave channel in front of the wave generator. The results of physical model tests performed with an absorbing wave maker based on this principle show that the problem of rereflection is reduced significantly when active absorption is performed. Finally, an absorbing directional wave generator for 3-D...... generator is capable of of reducing the problem of rereflection in multidirectional, irregular wave fields significantly....

  8. Problems of regional innovation strategy forming

    Directory of Open Access Journals (Sweden)

    I. M. Golova

    2010-09-01

    Full Text Available The author considered problems and contradictions of modern innovation policy in Russia. It is shown, that at present time regions are removed from management of science-technical complex and spatial priorities are not produced. It is a serious factor of risk for conservation perspectives of innovation development for Russia. With taking into account of world experience main districts of rise effects regional police were formulated. It is underlined, that creation conditions for transformation of regional authorities in active subjects of innovation policy is necessary condition for building vital innovation system. It is shown, that state innovation policy must be constructed at combination of next principles: a support science-technical potential of regionsgenerators of innovation and creation conditions for its realization; b using of innovations for evening-out disproportions of social-economic development between regions; c widening powers and financial possibilities of regions at management of innovation climate. Methodical approaches for making effective mechanisms of management of innovation processes of territory are opened. Typology of Russian regions with high and middle degree of innovation climate is proposed, which takes level of science and innovation potential of territory and also degree of comfort of social-economic conditions for development of innovation activity are offered. Peculiarities of innovation strategy for different types of regions are defined. This typology may be used for substantiation spatial priorities of innovation strategy of Russia.

  9. High-power quantum-dot superluminescent diodes with p-doped active region

    NARCIS (Netherlands)

    Rossetti, M.; Li, L.; Fiore, A.; Occhi, L.; Velez, C.; Mikhrin, S.; Kovsh, A.

    2006-01-01

    We demonstrate the use of p-doping in the active region of quantum-dot superluminescent diodes. Modal gain measurements and light output-current characteristics prove that p-doping is beneficial for achieving higher gain, higher output power, and better temperature stability

  10. Relating Alfvén Wave Heating Model to Observations of a Solar Active Region

    Science.gov (United States)

    Yoritomo, J. Y.; Van Ballegooijen, A. A.

    2012-12-01

    We compared images from the Solar Dynamics Observatory's (SDO) Atmospheric Imaging Assembly (AIA) with simulations of propagating and dissipating Alfvén waves from a three-dimensional magnetohydrodynamic (MHD) model (van Ballegooijen et. al 2011; Asgari-Targhi & van Ballegooijen 2012). The goal was to search for observational evidence of Alfvén waves in the solar corona and understand their role in coronal heating. We looked at one particular active region on the 5th of May 2012. Certain distinct loops in the SDO/AIA observations were selected and expanded. Movies were created from these selections in an attempt to discover transverse motions that may be Alfvén waves. Using a magnetogram of that day and the corresponding synoptic map, a potential field model was created for the active region. Three-dimensional MHD models for several loops in different locations in the active region were created. Each model specifies the temperature, pressure, magnetic field strength, average heating rate, and other parameters along the loop. We find that the heating is intermittent in the loops and reflection occurs at the transition region. For loops at larger and larger height, a point is reached where thermal non-equilibrium occurs. In the center this critical height is much higher than in the periphery of the active region. Lastly, we find that the average heating rate and coronal pressure decrease with increasing height in the corona. This research was supported by an NSF grant for the Smithsonian Astrophysical Observatory (SAO) Solar REU program and a SDO/AIA grant for the Smithsonian Astrophysical Observatory.

  11. Does regional disadvantage affect health-related sport and physical activity level? A multi-level analysis of individual behaviour.

    Science.gov (United States)

    Wicker, Pamela; Downward, Paul; Lera-López, Fernando

    2017-11-01

    This study examines the role of regional government quality in health-related participation in sport and physical activity among adults (18-64 years) in 28 European countries. The importance of the analysis rests in the relative autonomy that regional and local governments have over policy decisions connected with sport and physical activity. While existing studies have focussed on economic and infrastructural investment and expenditure, this research investigates the quality of regional governments across 208 regions within 28 European countries. The individual-level data stem from the 2013 Eurobarometer 80.2 (n = 18,675) and were combined with regional-level data from Eurostat. An individual's level of participation in sport and physical activity was measured by three variables reflecting whether an individual's activity level is below, meets, or exceeds the recommendations of the World Health Organization. The results of multi-level analyses reveal that regional government quality has a significant and positive association with individual participation in sport and physical activity at a level meeting or exceeding the guidelines. The impact is much larger than that of regional gross domestic product per capita, indicating that regional disadvantage in terms of political quality is more relevant than being disadvantaged in terms of economic wealth.

  12. The road to reorganization. A system keeps its regional network all in the family.

    Science.gov (United States)

    Haglund, C

    1989-11-01

    One prominent strategy health-care institutions are pursuing today is the formation of regional networks providing comprehensive continuums of care. Regional activities can be organized according to several distinct geographical parameters: city, county, state, or multistate regions. Although the different types of regionalization may be beneficial, they will generate different types of activities and benefits. Another consideration is that regional structures can range from very loose affiliations to complete ownership. In 1987 the Sisters of Providence health system, Seattle, initiated efforts to create a functionally integrated regional healthcare system in the Portland, OR, market, which had a good framework in place for developing a vertically and horizontally linked comprehensive continuum of care. The Oregon Management Committee, composed of local administrators, was established to identify issues and develop common objectives. The group developed a regional strategic plan and identified eight key areas to begin regionally coordinated activities. It began creating working relationships among institutional counterparts and program integration in several outpatient service areas where duplication was evident. Another effort involved greater coordination of marketing activities.

  13. Seasonal forecasting of lightning and thunderstorm activity in tropical and temperate regions of the world.

    Science.gov (United States)

    Dowdy, Andrew J

    2016-02-11

    Thunderstorms are convective systems characterised by the occurrence of lightning. Lightning and thunderstorm activity has been increasingly studied in recent years in relation to the El Niño/Southern Oscillation (ENSO) and various other large-scale modes of atmospheric and oceanic variability. Large-scale modes of variability can sometimes be predictable several months in advance, suggesting potential for seasonal forecasting of lightning and thunderstorm activity in various regions throughout the world. To investigate this possibility, seasonal lightning activity in the world's tropical and temperate regions is examined here in relation to numerous different large-scale modes of variability. Of the seven modes of variability examined, ENSO has the strongest relationship with lightning activity during each individual season, with relatively little relationship for the other modes of variability. A measure of ENSO variability (the NINO3.4 index) is significantly correlated to local lightning activity at 53% of locations for one or more seasons throughout the year. Variations in atmospheric parameters commonly associated with thunderstorm activity are found to provide a plausible physical explanation for the variations in lightning activity associated with ENSO. It is demonstrated that there is potential for accurately predicting lightning and thunderstorm activity several months in advance in various regions throughout the world.

  14. Next generation surveillance system (NGSS)

    International Nuclear Information System (INIS)

    Aparo, Massimo

    2006-01-01

    Development of 'functional requirements' for transparency systems may offer a near-term mode of regional cooperation. New requirements under development at the IAEA may provide a foundation for this potential activity. The Next Generation Surveillance System (NGSS) will become the new IAEA remote monitoring system Under new requirements the NGSS would attempt to use more commercial components to reduce cost, increase radiation survivability and further increase reliability. The NGSS must be available in two years due to rapidly approaching obsolescence in the existing DCM family. (author)

  15. Altered regional homogeneity of spontaneous brain activity in idiopathic trigeminal neuralgia

    Directory of Open Access Journals (Sweden)

    Wang Y

    2015-10-01

    Full Text Available Yanping Wang,1,2 Xiaoling Zhang,2 Qiaobing Guan,2 Lihong Wan,2 Yahui Yi,2 Chun-Feng Liu1 1Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, 2Department of Neurology, The Second Hospital of Jiaxing City, Jiaxing, Zhejiang Province, People’s Republic of China Abstract: The pathophysiology of idiopathic trigeminal neuralgia (ITN has conventionally been thought to be induced by neurovascular compression theory. Recent structural brain imaging evidence has suggested an additional central component for ITN pathophysiology. However, far less attention has been given to investigations of the basis of abnormal resting-state brain activity in these patients. The objective of this study was to investigate local brain activity in patients with ITN and its correlation with clinical variables of pain. Resting-state functional magnetic resonance imaging data from 17 patients with ITN and 19 age- and sex-matched healthy controls were analyzed using regional homogeneity (ReHo analysis, which is a data-driven approach used to measure the regional synchronization of spontaneous brain activity. Patients with ITN had decreased ReHo in the left amygdala, right parahippocampal gyrus, and left cerebellum and increased ReHo in the right inferior temporal gyrus, right thalamus, right inferior parietal lobule, and left postcentral gyrus (corrected. Furthermore, the increase in ReHo in the left precentral gyrus was positively correlated with visual analog scale (r=0.54; P=0.002. Our study found abnormal functional homogeneity of intrinsic brain activity in several regions in ITN, suggesting the maladaptivity of the process of daily pain attacks and a central role for the pathophysiology of ITN. Keywords: trigeminal neuralgia, resting fMRI, brain, chronic pain, local connectivity

  16. Economic and environmental study for the wind power generation in the region of Bajio; Estudio economico y medio ambiental para la generacion de energia eolica en la region del Bajio

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Patino, Jesus; Hernandez Figueroa, Miguel A.; Ireta Moreno, Fernando [Universidad de Guanajuato, Campus Irapuato-Salamanca, Salamanca, Guanajuato (Mexico)]. E-mail: jesusmp23@salamanca.ugto.mx; mahf@salamanca.ugto.mx; fireta@salamanca.ugto.mx; Rubio Maya, Carlos; Galvan Gonzalez, Sergio Ricardo [Universidad Michoacana de San Nicolas de Hidalgo, Morelia, Michoacan (Mexico)]. E-mail: rmaya@umich.mx; srgalvan@umich.mx

    2010-11-15

    The presented study is divided into two main issues for wind energy generation: the economical scope, and the environment. A comparison from different perspectives is made between both costs. The study is focused in the Mexico central region called Bajio, where the wind data is obtained. The usage of different types of wind turbines is planned to generate electricity, and a comparison is made between them in different aspects. An invest of 20 years is expected for this equip. While comparing the costs, the estimated by emissions of CO{sup 2} by kW/h generated (environmental cost), with these cost it is showed the quantities of CO{sup 2} that can be stopped of emitting to the atmosphere by the use of fossil fuels. The data encourages the use of renewable energy in relation with the wind potential in the region. This is how the presented study shows the options of decision making to implement and viability of the usage of wind turbines for the production of electric energy under the wind conditions provided by the Bajio region. [Spanish] El estudio que se presenta se divide en dos principales puntos para la generacion de energia eolica: el ambito economico y el medio ambiental. Se realiza un comparativo entre ambos costos desde diferentes perspectivas. El estudio se concentra en la region del Bajio donde se obtienen los datos del viento. Se plantea el uso de diversos tipos de aerogeneradores para la generacion de energia electrica comparandolos entre si en varios aspectos. Para estos equipos se tiene contemplada una inversion a 20 anos. En la comparativa de costos resalta el estimado por la emision de CO{sup 2} por kW/h generado (Costo medioambiental), con este costo se pone de manifiesto las cantidades de CO{sup 2} que se pueden dejar de enviar a la atmosfera por el uso de combustibles fosiles, los datos alientan el uso de la energia renovable en relacion tambien al potencial de viento que se tiene en la region. De esta manera, el estudio presentado en el trabajo

  17. Active-Reactive Additional Damping Control of a Doubly-Fed Induction Generator Based on Active Disturbance Rejection Control

    Directory of Open Access Journals (Sweden)

    Yanfeng Ma

    2018-05-01

    Full Text Available Large-scale wind power interfacing to the power grid has an impact on the stability of the power system. However, with an additional damping controller of the wind generator, new ways for improving system damping and suppressing the low frequency oscillation (LFO of power systems can be put forward. In this paper, an active-reactive power additional damping controller based on active disturbance rejection control (ADRC is proposed. In order to improve the precision of the controller, the theory of data driven control is adopted, using the numerical algorithms for subspace state space system identification (N4SID to obtain the two order model of the ADRC controlled object. Based on the identification model, the ADRC additional damping controller is designed. Taking a 2-area 4-machine system containing the doubly fed induction generator (DFIG wind farm as an example, it is verified that the active-reactive additional damping controller designed in this paper performs well in suppressing negative-damping LFO and forced power oscillation. When the operation state of the power system changes, it can still restrain the LFO effectively, showing stronger robustness and better effectiveness compared to the traditional proportional–integral–derivative (PID additional damping controller.

  18. Recent activity of the regional geologic structures in western Slovenia

    Directory of Open Access Journals (Sweden)

    Miloš Bavec

    2007-06-01

    Full Text Available Several important geological structures in the western Slovenia were identifiedas active and their activity was quantified. Geologic interpretation is based on the analysis of repeated leveling line campaigns data along the Sečovlje–Bled polygon. Taking intoaccount the limitations of the method – only the vertical component of displacement is measured – the following structures were identified as active:a juvenile syncline between Strunjan and Koper, the Kras Imbricate Structure, the Diva~a fault, the Ra{a fault, the Southalpine Front and the Julian Alps thrust. Vertical movement rate is relative, calculated with respect to the benchmark in Sečovlje. The largest uplift rate difference between Sečovlje and Bled is 7 mm/a.Vertical Geodynamic Activity (VGA is introduced as a link between geologic interpretation of geodetic measurements on one side and possible applications on the other as well as a mean of comparison between tectonically active regions.

  19. Pre-Excitation Studies for Rubidium-Plasma Generation

    CERN Document Server

    Aladi, M; Barna, I.F.; Czitrovszky, Aladar; Djotyan, Gagik; Dombi, Peter; Dzsotjan, David; FöLdes, Istvan; Hamar, Gergo; Ignacz, Peter; Kedves, Miklos; Kerekes, Attila; Levai, Peter; Marton, Istvan; Nagy, Attila; Oszetzky, Daniel; Pocsai, Mihaly; Racz, Peter; Raczkevi, Bela; Szigeti, Janos; Sörlei, Zsuzsa; Szipöcs, Robert; Varga, Dezso; Varga-Umbrich, Karoly; Varro, Sandor; Vamos, Lenard; Vesztergombi, György

    2014-01-01

    The key element in the Proton-Driven-Plasma-Wake-Field-Accelerator (AWAKE) project is the generation of highly uniform plasma from Rubidium vapor. The standard way to achieve full ionization is to use high power laser which can assure the over-barrier-ionization (OBI) along the 10 meters long active region. The Wigner-team in Budapest is investigating an alternative way of uniform plasma generation. The proposed Resonance Enhanced Multi Photon Ionization (REMPI) scheme probably can be realized by much less laser power. In the following the resonant pre-excitations of the Rb atoms are investigated, theoretically and the status report about the preparatory work on the experiment are presented.

  20. Level of hamstrings damage depending on force-generating capacity and creatine kinase activity

    OpenAIRE

    Carmona, Gerard; Alomar, Xavier; Mendiguchia, Jurdan; Serrano, David; Padullés, Josep Maria; Nescolarde Selva, Lexa Digna; Rodas Font, Gil; Cusso Calabuig, Roser; Guerrero, M.; Idoate, F.; Balius, Ramon; Cadefau, Joan

    2014-01-01

    The aim of the present study was to categorize the eccentric exercise-induced hamstrings damage by using easy measurable markers such as force-generating capacity and serum creatine kinase activity Peer Reviewed

  1. Regional air quality impacts of increased natural gas production and use in Texas.

    Science.gov (United States)

    Pacsi, Adam P; Alhajeri, Nawaf S; Zavala-Araiza, Daniel; Webster, Mort D; Allen, David T

    2013-04-02

    Natural gas use in electricity generation in Texas was estimated, for gas prices ranging from $1.89 to $7.74 per MMBTU, using an optimal power flow model. Hourly estimates of electricity generation, for individual electricity generation units, from the model were used to estimate spatially resolved hourly emissions from electricity generation. Emissions from natural gas production activities in the Barnett Shale region were also estimated, with emissions scaled up or down to match demand in electricity generation as natural gas prices changed. As natural gas use increased, emissions decreased from electricity generation and increased from natural gas production. Overall, NOx and SO2 emissions decreased, while VOC emissions increased as natural gas use increased. To assess the effects of these changes in emissions on ozone and particulate matter concentrations, spatially and temporally resolved emissions were used in a month-long photochemical modeling episode. Over the month-long photochemical modeling episode, decreases in natural gas prices typical of those experienced from 2006 to 2012 led to net regional decreases in ozone (0.2-0.7 ppb) and fine particulate matter (PM) (0.1-0.7 μg/m(3)). Changes in PM were predominantly due to changes in regional PM sulfate formation. Changes in regional PM and ozone formation are primarily due to decreases in emissions from electricity generation. Increases in emissions from increased natural gas production were offset by decreasing emissions from electricity generation for all the scenarios considered.

  2. We are what we do: Examining learner-generated content in the anatomy laboratory through the lens of activity theory.

    Science.gov (United States)

    Doubleday, Alison F; Wille, Sarah J

    2014-01-01

    Video and photography are often used for delivering content within the anatomical sciences. However, instructors typically produce these resources to provide instructional or procedural information. Although the benefits of learner-generated content have been explored within educational research, virtually no studies have investigated the use of learner-generated video and photograph content within anatomy dissection laboratories. This study outlines an activity involving learner-generated video diaries and learner-generated photograph assignments produced during anatomy laboratory sessions. The learner-generated photographs and videos provided instructors with a means of formative assessment and allowed instructors to identify evidence of collaborative behavior in the laboratory. Student questionnaires (n = 21) and interviews (n = 5), as well as in-class observations, were conducted to examine student perspectives on the laboratory activities. The quantitative and qualitative data were examined using the framework of activity theory to identify contradictions between student expectations of, and engagement with, the activity and the actual experiences of the students. Results indicate that learner-generated photograph and video content can act as a rich source of data on student learning processes and can be used for formative assessment, for observing collaborative behavior, and as a starting point for class discussions. This study stresses the idea that technology choice for activities must align with instructional goals. This research also highlights the utility of activity theory as a framework for assessing classroom and laboratory activities, demonstrating that this approach can guide the development of laboratory activities. © 2014 American Association of Anatomists.

  3. FORMATION OF CORONAL HOLES ON THE ASHES OF ACTIVE REGIONS

    International Nuclear Information System (INIS)

    Karachik, Nina V.; Pevtsov, Alexei A.; Abramenko, Valentyna I.

    2010-01-01

    We investigate the formation of isolated non-polar coronal holes (CHs) on the remnants of decaying active regions (ARs) at the minimum/early ascending phase of sunspot activity. We follow the evolution of four bipolar ARs and measure several parameters of their magnetic fields including total flux, imbalance, and compactness. As regions decay, their leading and following polarities exhibit different dissipation rates: loose polarity tends to dissipate faster than compact polarity. As a consequence, we see a gradual increase in flux imbalance inside a dissipating bipolar region, and later a formation of a CH in place of more compact magnetic flux. Out of four cases studied in detail, two CHs had formed at the following polarity of the decaying bipolar AR, and two CHs had developed in place of the leading polarity field. All four CHs contain a significant fraction of magnetic field of their corresponding AR. Using potential field extrapolation, we show that the magnetic field lines of these CHs were closed on the polar CH at the North, which at the time of the events was in imbalance with the polar CH at the South. This topology suggests that the observed phenomenon may play an important role in transformation of toroidal magnetic field to poloidal field, which is a key step in transitioning from an old solar cycle to a new one. The timing of this observed transition may indicate the end of solar cycle 23 and the beginning of cycle 24.

  4. Solar wind stream interaction regions throughout the heliosphere

    Science.gov (United States)

    Richardson, Ian G.

    2018-01-01

    This paper focuses on the interactions between the fast solar wind from coronal holes and the intervening slower solar wind, leading to the creation of stream interaction regions that corotate with the Sun and may persist for many solar rotations. Stream interaction regions have been observed near 1 AU, in the inner heliosphere (at ˜ 0.3-1 AU) by the Helios spacecraft, in the outer and distant heliosphere by the Pioneer 10 and 11 and Voyager 1 and 2 spacecraft, and out of the ecliptic by Ulysses, and these observations are reviewed. Stream interaction regions accelerate energetic particles, modulate the intensity of Galactic cosmic rays and generate enhanced geomagnetic activity. The remote detection of interaction regions using interplanetary scintillation and white-light imaging, and MHD modeling of interaction regions will also be discussed.

  5. FUZZY INFERENCE SYSTEM MODELING FOR BED ACTIVE CARBON RE-GENERATION PROCESS (CO2 GAS FACTORY CASE

    Directory of Open Access Journals (Sweden)

    S. Febriana

    2005-01-01

    Full Text Available Bed active carbon is one of the most important materials that had great impact in determining level of impurities in production of CO2 gas. In this particular factory case, there is unavailability of standard duration time of heating and cooling and steam flow rate for the re-generation process of bed active carbon. The paper discusses the fuzzy inference system for modeling of re-generation process of bed active carbon to find the optimum setting parameter. The fuzzy inference system was build using real historical daily processing data. After validation process, surface plot analysis was performed to find the optimum setting. The result of re-generation parameter setting is 9-10 hours of heating process, 4.66-5.32 hours of cooling process, and 1500-2500 kg/hr of steam flow rate.

  6. Neutralizing activities of caprine antibodies towards conserved regions of the HCV envelope glycoprotein E2

    Directory of Open Access Journals (Sweden)

    El-Shenawy Reem

    2011-08-01

    Full Text Available Abstract Anti HCV vaccine is not currently available and the present antiviral therapies fail to cure approximately half of the treated HCV patients. This study was designed to assess the immunogenic properties of genetically conserved peptides derived from the C-terminal region of HVR-1 and test their neutralizing activities in a step towards developing therapeutic and/or prophylactic immunogens against HCV infection. Antibodies were generated by vaccination of goats with synthetic peptides derived from HCV E2. Viral neutralizing capacity of the generated anti E2 antibodies was tested using in vitro assays. Goats immunized with E2 synthetic peptides termed p412 [a.a 412-419], p430 [a.a 430-447] and p517 [a.a 517-531] generated high titers of antibody responses 2 to 4.5 fold higher than comparable titers of antibodies to the same epitopes in chronic HCV patients. In post infection experiments of native HCV into cultured Huh7.5 cells anti p412 and anti p 517 were proven to be neutralizing to HCV genotype 4a from patients' sera (87.5% and 75% respectively. On the contrary anti p430 exhibited weak viral neutralization capacity on the same samples (31.25%. Furthermore Ab mixes containing anti p430 exhibited reduced viral neutralization properties. From these experiments one could predict that neutralization by Abs towards different E2-epitopes varies considerably and success in the enrichment of neutralization epitope-specific antibodies may be accompanied by favorable results in combating HCV infection. Also, E2 conserved peptides p517 and p412 represent potential components of a candidate peptide vaccine against HCV infection.

  7. Helium generated cold plasma finely regulates activation of human fibroblast-like primary cells.

    Directory of Open Access Journals (Sweden)

    Paola Brun

    Full Text Available Non-thermal atmospheric pressure plasmas are being developed for a wide range of health care applications, including wound healing. However in order to exploit the potential of plasma for clinical applications, the understanding of the mechanisms involved in plasma-induced activation of fibroblasts, the cells active in the healing process, is mandatory. In this study, the role of helium generated plasma in the tissue repairing process was investigated in cultured human fibroblast-like primary cells, and specifically in hepatic stellate cells and intestinal subepithelial myofibroblasts. Five minutes after treatment, plasma induced formation of reactive oxygen species (ROS in cultured cells, as assessed by flow cytometric analysis of fluorescence-activated 2',7'-dichlorofluorescein diacetate probe. Plasma-induced intracellular ROS were characterized by lower concentrations and shorter half-lives with respect to hydrogen peroxide-induced ROS. Moreover ROS generated by plasma treatment increased the expression of peroxisome proliferator activated receptor (PPAR-γ, nuclear receptor that modulates the inflammatory responses. Plasma exposure promoted wound healing in an in vitro model and induced fibroblast migration and proliferation, as demonstrated, respectively, by trans-well assay and partitioning between daughter cells of carboxyfluorescein diacetate succinimidyl ester fluorescent dye. Plasma-induced fibroblast migration and proliferation were found to be ROS-dependent as cellular incubation with antioxidant agents (e.g. N-acetyl L-cysteine cancelled the biological effects. This study provides evidence that helium generated plasma promotes proliferation and migration in liver and intestinal fibroblast-like primary cells mainly by increasing intracellular ROS levels. Since plasma-evoked ROS are time-restricted and elicit the PPAR-γ anti-inflammatory molecular pathway, this strategy ensures precise regulation of human fibroblast activation and

  8. Emissions reduction and economic implications of renewable energy market penetration of power generation for residential consumption in the MENA region

    International Nuclear Information System (INIS)

    El Fadel, M.; Rachid, G.; El-Samra, R.; Bou Boutros, G.; Hashisho, J.

    2013-01-01

    This paper examines the implications of renewable energy (RE) deployment in power generation for residential consumption in the Middle East and North Africa (MENA) region under various RE penetration targets. A comparative assessment revealed a great heterogeneity among countries with Turkey dominating as the highest emitter. At the sub-regional level, the Middle East sub-region contributes more than double the GHG emissions estimated for the Gulf and North Africa sub-regions with all sub-regions achieving reductions in the range of 6–38% depending on the RE target penetration and promising up to 54% savings on investment excluding positive externalities associated with the offset of greenhouse gas (GHG) emissions savings. - Highlights: ► Heterogeneity in GHG emissions in MENA region with Turkey contributing the most. ► Average regional GHG tCO 2 e/capita of 0.42 decreases to 0.17 with RE penetration. ► GHG emissions regional reduction reaches 8–36% depending on RE target penetration. ► Return on investment in RE promises up to 54% savings excluding positive externalities. ► Carbon credits offer economic incentives rendering RE investment more attractive.

  9. On the area expansion of magnetic flux tubes in solar active regions

    Energy Technology Data Exchange (ETDEWEB)

    Dudík, Jaroslav [DAMTP, CMS, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA (United Kingdom); Dzifčáková, Elena [Astronomical Institute of the Academy of Sciences of the Czech Republic, Fričova 298, 251 65 Ondřejov (Czech Republic); Cirtain, Jonathan W., E-mail: J.Dudik@damtp.cam.ac.uk, E-mail: elena@asu.cas.cz [NASA Marshall Space Flight Center, VP 62, Huntsville, AL 35812 (United States)

    2014-11-20

    We calculated the three-dimensional (3D) distribution of the area expansion factors in a potential magnetic field, extrapolated from the high-resolution Hinode/SOT magnetogram of the quiescent active region NOAA 11482. Retaining only closed loops within the computational box, we show that the distribution of area expansion factors show significant structure. Loop-like structures characterized by locally lower values of the expansion factor are embedded in a smooth background. These loop-like flux tubes have squashed cross-sections and expand with height. The distribution of the expansion factors show an overall increase with height, allowing an active region core characterized by low values of the expansion factor to be distinguished. The area expansion factors obtained from extrapolation of the Solar Optical Telescope magnetogram are compared to those obtained from an approximation of the observed magnetogram by a series of 134 submerged charges. This approximation retains the general flux distribution in the observed magnetogram, but removes the small-scale structure in both the approximated magnetogram and the 3D distribution of the area expansion factors. We argue that the structuring of the expansion factor can be a significant ingredient in producing the observed structuring of the solar corona. However, due to the potential approximation used, these results may not be applicable to loops exhibiting twist or to active regions producing significant flares.

  10. Does selection against transcriptional interference shape retroelement-free regions in mammalian genomes?

    DEFF Research Database (Denmark)

    Mourier, Tobias; Willerslev, Eske

    2008-01-01

    in generating and maintaining retroelement-free regions in the human genome. METHODOLOGY/PRINCIPAL FINDINGS: Based on the known transcriptional properties of retroelements, we expect long interspersed elements (LINEs) to be able to display a high degree of transcriptional interference. In contrast, we expect......BACKGROUND: Eukaryotic genomes are scattered with retroelements that proliferate through retrotransposition. Although retroelements make up around 40 percent of the human genome, large regions are found to be completely devoid of retroelements. This has been hypothesised to be a result of genomic...... activity of LINEs has been identified previously. CONCLUSIONS/SIGNIFICANCE: Our observations are consistent with the notion that selection against transcriptional interference has contributed to the maintenance and/or generation of retroelement-free regions in the human genome....

  11. Small Coronal Holes Near Active Regions as Sources of Slow Solar Wind

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y.-M., E-mail: yi.wang@nrl.navy.mil [Space Science Division, Naval Research Laboratory, Washington, DC 20375 (United States)

    2017-06-01

    We discuss the nature of the small areas of rapidly diverging, open magnetic flux that form in the strong unipolar fields at the peripheries of active regions (ARs), according to coronal extrapolations of photospheric field measurements. Because such regions usually have dark counterparts in extreme-ultraviolet (EUV) images, we refer to them as coronal holes, even when they appear as narrow lanes or contain sunspots. Revisiting previously identified “AR sources” of slow solar wind from 1998 and 1999, we find that they are all associated with EUV coronal holes; the absence of well-defined He i 1083.0 nm counterparts to some of these holes is attributed to the large flux of photoionizing radiation from neighboring AR loops. Examining a number of AR-associated EUV holes during the 2014 activity maximum, we confirm that they are characterized by wind speeds of ∼300–450 km s{sup −1}, O{sup 7+}/O{sup 6+} ratios of ∼0.05–0.4, and footpoint field strengths typically of order 30 G. The close spacing between ARs at sunspot maximum limits the widths of unipolar regions and their embedded holes, while the continual emergence of new flux leads to rapid changes in the hole boundaries. Because of the highly nonradial nature of AR fields, the smaller EUV holes are often masked by the overlying canopy of loops, and may be more visible toward one solar limb than at central meridian. As sunspot activity declines, the AR remnants merge to form much larger, weaker, and longer-lived unipolar regions, which harbor the “classical” coronal holes that produce recurrent high-speed streams.

  12. Bioimpedance Harmonic Analysis as a Diagnostic Tool to Assess Regional Circulation and Neural Activity

    International Nuclear Information System (INIS)

    Mudraya, I S; Revenko, S V; Khodyreva, L A; Markosyan, T G; Dudareva, A A; Ibragimov, A R; Romich, V V; Kirpatovsky, V I

    2013-01-01

    The novel technique based on harmonic analysis of bioimpedance microvariations with original hard- and software complex incorporating a high-resolution impedance converter was used to assess the neural activity and circulation in human urinary bladder and penis in patients with pelvic pain, erectile dysfunction, and overactive bladder. The therapeutic effects of shock wave therapy and Botulinum toxin detrusor injections were evaluated quantitatively according to the spectral peaks at low 0.1 Hz frequency (M for Mayer wave), respiratory (R) and cardiac (C) rhythms with their harmonics. Enhanced baseline regional neural activity identified according to M and R peaks was found to be presumably sympathetic in pelvic pain patients, and parasympathetic – in patients with overactive bladder. Total pulsatile activity and pulsatile resonances found in the bladder as well as in the penile spectrum characterised regional circulation and vascular tone. The abnormal spectral parameters characteristic of the patients with genitourinary diseases shifted to the norm in the cases of efficient therapy. Bioimpedance harmonic analysis seems to be a potent tool to assess regional peculiarities of circulatory and autonomic nervous activity in the course of patient treatment.

  13. Bioimpedance Harmonic Analysis as a Diagnostic Tool to Assess Regional Circulation and Neural Activity

    Science.gov (United States)

    Mudraya, I. S.; Revenko, S. V.; Khodyreva, L. A.; Markosyan, T. G.; Dudareva, A. A.; Ibragimov, A. R.; Romich, V. V.; Kirpatovsky, V. I.

    2013-04-01

    The novel technique based on harmonic analysis of bioimpedance microvariations with original hard- and software complex incorporating a high-resolution impedance converter was used to assess the neural activity and circulation in human urinary bladder and penis in patients with pelvic pain, erectile dysfunction, and overactive bladder. The therapeutic effects of shock wave therapy and Botulinum toxin detrusor injections were evaluated quantitatively according to the spectral peaks at low 0.1 Hz frequency (M for Mayer wave), respiratory (R) and cardiac (C) rhythms with their harmonics. Enhanced baseline regional neural activity identified according to M and R peaks was found to be presumably sympathetic in pelvic pain patients, and parasympathetic - in patients with overactive bladder. Total pulsatile activity and pulsatile resonances found in the bladder as well as in the penile spectrum characterised regional circulation and vascular tone. The abnormal spectral parameters characteristic of the patients with genitourinary diseases shifted to the norm in the cases of efficient therapy. Bioimpedance harmonic analysis seems to be a potent tool to assess regional peculiarities of circulatory and autonomic nervous activity in the course of patient treatment.

  14. Generation of knockout rabbits using transcription activator-like effector nucleases.

    Science.gov (United States)

    Wang, Yu; Fan, Nana; Song, Jun; Zhong, Juan; Guo, Xiaogang; Tian, Weihua; Zhang, Quanjun; Cui, Fenggong; Li, Li; Newsome, Philip N; Frampton, Jon; Esteban, Miguel A; Lai, Liangxue

    2014-01-01

    Zinc-finger nucleases and transcription activator-like effector nucleases are novel gene-editing platforms contributing to redefine the boundaries of modern biological research. They are composed of a non-specific cleavage domain and a tailor made DNA-binding module, which enables a broad range of genetic modifications by inducing efficient DNA double-strand breaks at desired loci. Among other remarkable uses, these nucleases have been employed to produce gene knockouts in mid-size and large animals, such as rabbits and pigs, respectively. This approach is cost effective, relatively quick, and can produce invaluable models for human disease studies, biotechnology or agricultural purposes. Here we describe a protocol for the efficient generation of knockout rabbits using transcription activator-like effector nucleases, and a perspective of the field.

  15. Centro Regional de Ciencias Nucleares (a Brazilian regional center for nuclear sciences) - activities report - 1999; Centro Regional de Ciencias Nucleares - relatorio de atividades - 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-01

    The annual activities report of 1999 of nuclear sciences regional center - Brazilian organization - introduces the next main topics: institutional relations; sectorial actions - logistic support and training, laboratory of radiation protection and dosimetry, laboratory of metrology, laboratory of chemical characterization; technical and scientific events; and financial resources and perspectives for 2000.

  16. OUTFLOWS AND DARK BANDS AT ARCADE-LIKE ACTIVE REGION CORE BOUNDARIES

    Energy Technology Data Exchange (ETDEWEB)

    Scott, J. T.; Martens, P. C. H.; Tarr, L. [Department of Physics, Montana State University, Bozeman, MT 59717 (United States)

    2013-03-10

    Observations from the EUV Imaging Spectrometer (EIS) on board Hinode have revealed outflows and non-thermal line broadening in low intensity regions at the edges of active regions (ARs). We use data from Hinode's EIS, Solar Dynamic Observatory's Atmospheric Imaging Assembly and Helioseismic and Magnetic Imager, and the Transition Region and Coronal Explorer instrument to investigate the boundaries of arcade-like AR cores for NOAA ARs 11112, 10978, and 9077. A narrow, low intensity region that is observed at the core's periphery as a dark band shows outflows and increased spectral line broadening. This dark band is found to exist for days and appears between the bright coronal loop structures of different coronal topologies. We find a case where the dark band region is formed between the magnetic field from emerging flux and the field of the pre-existing flux. A magnetic field extrapolation indicates that this dark band is coincident with the spine lines or magnetic separatrices in the extrapolated field. This occurs over unipolar regions where the brightened coronal field is separated in connectivity and topology. This separation does not appear to be infinitesimal and an initial estimate of the minimum distance of separation is found to be Almost-Equal-To 1.5-3.5 Mm.

  17. Hi-C Observations of an Active Region Corona, and Investigation of the Underlying Magnetic Structure

    Science.gov (United States)

    Tiwari, S. K.; Alexander, C. E.; Winebarger, A.; Moore, R. L.

    2014-01-01

    The solar corona is much hotter (>=10(exp 6) K) than its surface (approx 6000 K), puzzling astrophysicists for several decades. Active region (AR) corona is again hotter than the quiet Sun (QS) corona by a factor of 4-10. The most widely accepted mechanism that could heat the active region corona is the energy release by current dissipation via reconnection of braided magnetic field structure, first proposed by E. N. Parker three decades ago. The first observational evidence for this mechanism has only recently been presented by Cirtain et al. by using High-resolution Coronal Imager (Hi-C) observations of an AR corona at a spatial resolution of 0.2 arcsec, which is required to resolve the coronal loops, and was not available before the rocket flight of Hi-C in July 2012. The Hi-C project is led by NASA/MSFC. In the case of the QS, work done by convection/granulation on the inter-granular feet of the coronal field lines translates into the heat observed in the corona. In the case of the AR, as here, there could be flux emergence, cancellation/submergence, or shear flows generating large stress and tension in coronal field loops which is released as heat in the corona. We are currently investigating the changes taking place in photospheric feet of the magnetic field involved with brightenings in the Hi-C AR corona. For this purpose, we are also using SDO/AIA data of +/- 2 hours around the 5 minutes Hi-C flight. In the present talk, I will first summarize some of the results of the Hi-C observations and then present some results from our recent analysis on what photospheric processes feed the magnetic energy that dissipates into heat in coronal loops.

  18. Role of regional policies in promoting networking and innovation activity of firms

    OpenAIRE

    Kirsi Mukkala; Jari Ritsilä

    2004-01-01

    The success of firms and regions is increasingly defined by their innovation and learning capabilities. It has been emphasized in several studies that a local operational environment may have a positive impact on innovation activity of firms. From policy point of view, the relationship between firms and their local environment is an important research topic. The purpose of this paper is to explore whether there is a demand for regional policy makers in promoting innovative and networking acti...

  19. Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.

    OpenAIRE

    Gough, N M; Bernard, O

    1981-01-01

    To assess the contribution to immunoglobulin heavy chain diversity made by recombination between variable region (VH) genes and joining region (JH) genes, we have determined the sequence of about 2000 nucleotides spanning the rearranged JH gene cluster associated with the VH gene expressed in plasmacytoma HPC76. The active VH76 gene has recombined with the second germ-line JH gene. The region we have studied contains two other JH genes, designated JH3 and JH4. No other JH gene was found withi...

  20. Contextual Multi-Scale Region Convolutional 3D Network for Activity Detection

    KAUST Repository

    Bai, Yancheng

    2018-01-28

    Activity detection is a fundamental problem in computer vision. Detecting activities of different temporal scales is particularly challenging. In this paper, we propose the contextual multi-scale region convolutional 3D network (CMS-RC3D) for activity detection. To deal with the inherent temporal scale variability of activity instances, the temporal feature pyramid is used to represent activities of different temporal scales. On each level of the temporal feature pyramid, an activity proposal detector and an activity classifier are learned to detect activities of specific temporal scales. Temporal contextual information is fused into activity classifiers for better recognition. More importantly, the entire model at all levels can be trained end-to-end. Our CMS-RC3D detector can deal with activities at all temporal scale ranges with only a single pass through the backbone network. We test our detector on two public activity detection benchmarks, THUMOS14 and ActivityNet. Extensive experiments show that the proposed CMS-RC3D detector outperforms state-of-the-art methods on THUMOS14 by a substantial margin and achieves comparable results on ActivityNet despite using a shallow feature extractor.

  1. Contextual Multi-Scale Region Convolutional 3D Network for Activity Detection

    KAUST Repository

    Bai, Yancheng; Xu, Huijuan; Saenko, Kate; Ghanem, Bernard

    2018-01-01

    Activity detection is a fundamental problem in computer vision. Detecting activities of different temporal scales is particularly challenging. In this paper, we propose the contextual multi-scale region convolutional 3D network (CMS-RC3D) for activity detection. To deal with the inherent temporal scale variability of activity instances, the temporal feature pyramid is used to represent activities of different temporal scales. On each level of the temporal feature pyramid, an activity proposal detector and an activity classifier are learned to detect activities of specific temporal scales. Temporal contextual information is fused into activity classifiers for better recognition. More importantly, the entire model at all levels can be trained end-to-end. Our CMS-RC3D detector can deal with activities at all temporal scale ranges with only a single pass through the backbone network. We test our detector on two public activity detection benchmarks, THUMOS14 and ActivityNet. Extensive experiments show that the proposed CMS-RC3D detector outperforms state-of-the-art methods on THUMOS14 by a substantial margin and achieves comparable results on ActivityNet despite using a shallow feature extractor.

  2. Particle acceleration in solar active regions being in the state of self-organized criticality.

    Science.gov (United States)

    Vlahos, Loukas

    We review the recent observational results on flare initiation and particle acceleration in solar active regions. Elaborating a statistical approach to describe the spatiotemporally intermittent electric field structures formed inside a flaring solar active region, we investigate the efficiency of such structures in accelerating charged particles (electrons and protons). The large-scale magnetic configuration in the solar atmosphere responds to the strong turbulent flows that convey perturbations across the active region by initiating avalanche-type processes. The resulting unstable structures correspond to small-scale dissipation regions hosting strong electric fields. Previous research on particle acceleration in strongly turbulent plasmas provides a general framework for addressing such a problem. This framework combines various electromagnetic field configurations obtained by magnetohydrodynamical (MHD) or cellular automata (CA) simulations, or by employing a statistical description of the field’s strength and configuration with test particle simulations. We work on data-driven 3D magnetic field extrapolations, based on a self-organized criticality models (SOC). A relativistic test-particle simulation traces each particle’s guiding center within these configurations. Using the simulated particle-energy distributions we test our results against observations, in the framework of the collisional thick target model (CTTM) of solar hard X-ray (HXR) emission and compare our results with the current observations.

  3. Seeking the win/win alternative: Negotiations for regional access 1993-1996

    International Nuclear Information System (INIS)

    Visocki, Kathryn; Bremen, Sherol S.

    1992-01-01

    The Low-Level Radioactive Waste Policy Act (The Policy Act or LLWPA) of 1980 gave each state responsibility for dealing with its own low-level radioactive wastes (LLRW), and encouraged them to align themselves in regional compacts in order to do so. Now, many years and millions of dollars later, states and compacts are fighting legal and other battles to site the low-level radioactive waste disposal facilities so essential to continuing the power generation, medical research, and industrial activities enjoyed by United States citizens today. Delays in siting are causing a new set of problems associated with an interim period beginning in 1993 and lasting for variable durations from region to region. Existing disposal facilities will close, and the new generation of disposal facilities will not yet be open. In the Southeast, the first regional disposal facility in Barnwell, South Carolina is scheduled to close on December 31, 1992. A second regional facility is being sited in North Carolina, but it is not scheduled to open until February of 1996. The authors outline the possible options for low-level radio-active waste management in the Southeast during its three-year interim period and explain the process being used by the Southeast Compact Commission to explore the feasibility of each option. The authors conclude that ultimately the implementation of the LLWPA will be successful. (author)

  4. Solar irridiance variations and solar activity

    International Nuclear Information System (INIS)

    Willson, R.C.

    1982-01-01

    A mean value for the 1 AU total solar irradiance of 1368.2 W/m 2 and a downward trend of 0.05% per year were derived from measurements by the Active Cavity Radiometer Irradiance Monitor (ACRIM) experiment on the Solar Maximum Mission during 1980. Distinct temporary solar irradiance decreases associated with solar activity maxima were observed with a series of nine dips from April to October recurring at fairly regular intervals averaging 24 days. The decreases correlate inversely with sunspot area, 2800-MHz flux, and Zurich sunspot number. Dominant periods common to the irradiance and sunspot area power spectra link the irradiance decreases to sunspot flux deficit in solar active regions. Evidence of significant total irradiance modulation by facular flux excess is cited. A persistent radiative cycle of active regions consistent with the ACRIM irradiance results and the morphology of solar active regions was found. The pattern of regularly recurrent active region maxima between April and October suggests an asymmetry in solar activity generation during this period

  5. On transient events in the upper atmosphere generated away of thunderstorm regions

    Science.gov (United States)

    Morozenko, V.; Garipov, G.; Khrenov, B.; Klimov, P.; Panasyuk, M.; Sharakin, S.; Zotov, M.

    2011-12-01

    Experimental data on transient events in UV and Red-IR ranges obtained in the MSU missions "Unversitetsky-Tatiana" (wavelengths 300-400 nm) and "Unversitetsky-Tatiana-2" (wavelengths 300-400 nm and 600-800 nm), published by Garipov et al, in 2010 at COSPAR session http://www.cospar2010.org, at TEPA conference http://www.aragats.am/Conferences/tepa2010 and in 2011 by Sadovnichy et al, Solar System Research, 45, #1, 3-29 (2011); Vedenkin et al, JETP, v. 140, issue 3(9), 1-11 (2011) demonstrated existence of transients at large distances (up to thousands km) away of cloud thunderstorm regions. Those "remote" transients are short (1-5 msec) and are less luminous than the transients above thunderstorm regions. The ratio of Red-IR to UV photon numbers in those transients indicates high altitude of their origin (~70 km). Important observation facts are also: 1. a change of the exponent in transient distribution on luminosity Q ("-1" for photon numbers Q=1020 -1023 to "-2" for Q>1023), 2. a change of global distribution of transient with their luminosity (transients with Q>1023 are concentrated in equatorial range above continents, while transients with low luminosity are distributed more uniformly), 3. a phenomenon of transient sequences in one satellite orbit which is close to geomagnetic meridian. In the present paper phenomenological features of transients are explained in assumption that the observed transients have to be divided in two classes: 1. transients related to local, lower in the atmosphere, lightning at distance not more than hundreds km from satellite detector field of view in the atmosphere and 2. transients generated by far away lightning. Local transients are luminous and presumably are events called "transient luminous events" (TLE). In distribution on luminosity those events have some threshold Q~1023 and their differential luminosity distribution is approximated by power law exponent "-2". Remote transients have to be considered separately. Their

  6. Impact of unemployment and alcoholism on suicidal activity in the Saratov region

    Directory of Open Access Journals (Sweden)

    Bachilo Е. V.

    2011-09-01

    Full Text Available The research goal is to study the spread of completed and uncompleted suicides in the Saratov region during the period of 2001-2010, and influence of unemployment and alcohol abuse on suicidal behavior of the population in the most unfavourable areas of the region. To conduct the research elaborated questionnaires, describing suicidal and drug situations in the Saratov region during 2001-2010, and the reports of the Ministry of Employment, Labour and Migration in the Saratov region were used. Results: Areas with the highest rate of suicidal activity during 2001-2010 were identified (Balakovo, Engels, Dukhovnitsky, Pugachev, Perelub and Arkadak. In each of these areas correlation between the level of suicide and alcoholism and unemployment levels of the population were established. The research results allowed identifying some predictors of suicidal behavior for the specific area. These predictors will be included in «The Map of the predictors of suicide risk in the Saratov region». It improves assistance in suicidal situations and reduces suicides

  7. Testing the Accuracy of Data-driven MHD Simulations of Active Region Evolution

    Energy Technology Data Exchange (ETDEWEB)

    Leake, James E.; Linton, Mark G. [U.S. Naval Research Laboratory, 4555 Overlook Avenue, SW, Washington, DC 20375 (United States); Schuck, Peter W., E-mail: james.e.leake@nasa.gov [NASA Goddard Space Flight Center, 8800 Greenbelt Road, Greenbelt, MD 20771 (United States)

    2017-04-01

    Models for the evolution of the solar coronal magnetic field are vital for understanding solar activity, yet the best measurements of the magnetic field lie at the photosphere, necessitating the development of coronal models which are “data-driven” at the photosphere. We present an investigation to determine the feasibility and accuracy of such methods. Our validation framework uses a simulation of active region (AR) formation, modeling the emergence of magnetic flux from the convection zone to the corona, as a ground-truth data set, to supply both the photospheric information and to perform the validation of the data-driven method. We focus our investigation on how the accuracy of the data-driven model depends on the temporal frequency of the driving data. The Helioseismic and Magnetic Imager on NASA’s Solar Dynamics Observatory produces full-disk vector magnetic field measurements at a 12-minute cadence. Using our framework we show that ARs that emerge over 25 hr can be modeled by the data-driving method with only ∼1% error in the free magnetic energy, assuming the photospheric information is specified every 12 minutes. However, for rapidly evolving features, under-sampling of the dynamics at this cadence leads to a strobe effect, generating large electric currents and incorrect coronal morphology and energies. We derive a sampling condition for the driving cadence based on the evolution of these small-scale features, and show that higher-cadence driving can lead to acceptable errors. Future work will investigate the source of errors associated with deriving plasma variables from the photospheric magnetograms as well as other sources of errors, such as reduced resolution, instrument bias, and noise.

  8. Simulating secondary organic aerosol in a regional air quality model using the statistical oxidation model - Part 1: Assessing the influence of constrained multi-generational ageing

    Science.gov (United States)

    Jathar, S. H.; Cappa, C. D.; Wexler, A. S.; Seinfeld, J. H.; Kleeman, M. J.

    2016-02-01

    Multi-generational oxidation of volatile organic compound (VOC) oxidation products can significantly alter the mass, chemical composition and properties of secondary organic aerosol (SOA) compared to calculations that consider only the first few generations of oxidation reactions. However, the most commonly used state-of-the-science schemes in 3-D regional or global models that account for multi-generational oxidation (1) consider only functionalization reactions but do not consider fragmentation reactions, (2) have not been constrained to experimental data and (3) are added on top of existing parameterizations. The incomplete description of multi-generational oxidation in these models has the potential to bias source apportionment and control calculations for SOA. In this work, we used the statistical oxidation model (SOM) of Cappa and Wilson (2012), constrained by experimental laboratory chamber data, to evaluate the regional implications of multi-generational oxidation considering both functionalization and fragmentation reactions. SOM was implemented into the regional University of California at Davis / California Institute of Technology (UCD/CIT) air quality model and applied to air quality episodes in California and the eastern USA. The mass, composition and properties of SOA predicted using SOM were compared to SOA predictions generated by a traditional two-product model to fully investigate the impact of explicit and self-consistent accounting of multi-generational oxidation.Results show that SOA mass concentrations predicted by the UCD/CIT-SOM model are very similar to those predicted by a two-product model when both models use parameters that are derived from the same chamber data. Since the two-product model does not explicitly resolve multi-generational oxidation reactions, this finding suggests that the chamber data used to parameterize the models captures the majority of the SOA mass formation from multi-generational oxidation under the conditions

  9. Structural integrity assessment of steam generator tubes deteriorated through primary water stress corrosion cracking in transition region of tube expansion

    International Nuclear Information System (INIS)

    Silveira, Helvecio Carlos Klinke da

    2002-01-01

    In PWR plants, steam generator tube degradation has been one of the most important economical concerns, besides causing operational safety problems. In this work, a survey of steam generator tube degradation modes is done. Degradation mechanisms and influence factors are introduced and discussed. The importance of stress corrosion cracking, especially in transition region of tube expansion zone, is underlined. The actual steam generator tube plugging criteria are conservative. Proposed alternative criteria are introduced and discussed. Distinction is done to structural integrity assessment of defective tubes. Real data of tube defect indications of axial cracks in expansion transition zone due to primary water stress corrosion cracking are used in analysis. Results allow discussing application aspects of deterministic and probabilistic criteria on structural integrity assessment of tubes with defect indications. Applied models are specifics, but the application of concept may be extended to other steam generator tube degradation modes. (author)

  10. THEORETICAL APPROACHES TO ASSESS EFFICIENCY OF THE TRANSFORMATION OF THE KEY BUSINESS PROCESSES IN THE PUBLISHING AND PRINTING ACTIVITIES IN THE REGION

    Directory of Open Access Journals (Sweden)

    Volodymyr Bazyliuk

    2016-11-01

    Full Text Available The purpose of the paper is the theoretical study and the analysis of the basic methodological approaches to assess the effectiveness of the transformation of key business processes in the PPA (publishing and printing activity in the region in order to choose the best option. Methodology. The overview of the main assessment methods of the effectiveness of business processes: EVA (Economic value added; ABC (Activity-based costing; Tableau of bord and BSC (Balanced Scorecard is provided. In order to ensure the formalization of the intergrated assessment of the effectiveness of the business process in the publishing and printing activities in the region it is suggested to apply to the methodological apparatus of the fuzzy sets. Statistical analysis, comparison and synthesis are necessary to study the efficiency of the transformation of the key business processes in the PPA in the region. Results. The review and analysis of the most common methods for evaluating the effectiveness of the transformation of key business processes were conducted; the basic advantages and disadvantages of each of the proposed methods in the light of PPA were studied. It was proved that a single business process involves the use of a scorecard that is specific and peculiar for it only whereas completeness of its analysis depends on the kind of the business process: basic, developmental, managing or providing one. The approach to the formalization of the integrated assememnt of the effectiveness of business process in PPA in the region, based on the theory of fuzzy sets was formulated. Practical significance. The mathematical formulation of the problem, an integrated assessment of the efficiency of the business process for each of the possible options for its implementation was developed, and the algorithm of assessing the effectiveness of the business process in the PPA in the region was generated by the apparatus of fuzzy sets. Value/originality. Implementing the

  11. Auditory evoked fields to vocalization during passive listening and active generation in adults who stutter.

    Science.gov (United States)

    Beal, Deryk S; Cheyne, Douglas O; Gracco, Vincent L; Quraan, Maher A; Taylor, Margot J; De Nil, Luc F

    2010-10-01

    We used magnetoencephalography to investigate auditory evoked responses to speech vocalizations and non-speech tones in adults who do and do not stutter. Neuromagnetic field patterns were recorded as participants listened to a 1 kHz tone, playback of their own productions of the vowel /i/ and vowel-initial words, and actively generated the vowel /i/ and vowel-initial words. Activation of the auditory cortex at approximately 50 and 100 ms was observed during all tasks. A reduction in the peak amplitudes of the M50 and M100 components was observed during the active generation versus passive listening tasks dependent on the stimuli. Adults who stutter did not differ in the amount of speech-induced auditory suppression relative to fluent speakers. Adults who stutter had shorter M100 latencies for the actively generated speaking tasks in the right hemisphere relative to the left hemisphere but the fluent speakers showed similar latencies across hemispheres. During passive listening tasks, adults who stutter had longer M50 and M100 latencies than fluent speakers. The results suggest that there are timing, rather than amplitude, differences in auditory processing during speech in adults who stutter and are discussed in relation to hypotheses of auditory-motor integration breakdown in stuttering. Copyright 2010 Elsevier Inc. All rights reserved.

  12. Regional cerebral blood flow in psychiatry: The resting and activated brains of schizophrenic patients

    International Nuclear Information System (INIS)

    Gur, R.E.

    1984-01-01

    The investigation of regional brain functioning in schizophrenia has been based on behavioral techniques. Although results are sometimes inconsistent, the behavioral observations suggest left hemispheric dysfunction and left hemispheric overreaction. Recent developments in neuroimaging technology make possible major refinements in assessing regional brain function. Both anatomical and physiological information now be used to study regional brain development in psychiatric disorders. This chapter describes the application of one method - the xenon-133 technique for measuring regional cerebral blood flow (rCBF) - in studying the resting and activated brains of schizoprenic patients

  13. MINIFILAMENT ERUPTIONS THAT DRIVE CORONAL JETS IN A SOLAR ACTIVE REGION

    International Nuclear Information System (INIS)

    Sterling, Alphonse C.; Moore, Ronald L.; Falconer, David A.; Panesar, Navdeep K.; Akiyama, Sachiko; Yashiro, Seiji; Gopalswamy, Nat

    2016-01-01

    We present observations of eruptive events in an active region adjacent to an on-disk coronal hole on 2012 June 30, primarily using data from the Solar Dynamics Observatory ( SDO )/Atmospheric Imaging Assembly (AIA), SDO /Helioseismic and Magnetic Imager (HMI), and STEREO - B . One eruption is of a large-scale (∼100″) filament that is typical of other eruptions, showing slow-rise onset followed by a faster-rise motion starting as flare emissions begin. It also shows an “EUV crinkle” emission pattern, resulting from magnetic reconnections between the exploding filament-carrying field and surrounding field. Many EUV jets, some of which are surges, sprays and/or X-ray jets, also occur in localized areas of the active region. We examine in detail two relatively energetic ones, accompanied by GOES M1 and C1 flares, and a weaker one without a GOES signature. All three jets resulted from small-scale (∼20″) filament eruptions consistent with a slow rise followed by a fast rise occurring with flare-like jet-bright-point brightenings. The two more-energetic jets showed crinkle patters, but the third jet did not, perhaps due to its weakness. Thus all three jets were consistent with formation via erupting minifilaments, analogous to large-scale filament eruptions and to X-ray jets in polar coronal holes. Several other energetic jets occurred in a nearby portion of the active region; while their behavior was also consistent with their source being minifilament eruptions, we could not confirm this because their onsets were hidden from our view. Magnetic flux cancelation and emergence are candidates for having triggered the minifilament eruptions.

  14. Particle Acceleration in a Statistically Modeled Solar Active-Region Corona

    Science.gov (United States)

    Toutounzi, A.; Vlahos, L.; Isliker, H.; Dimitropoulou, M.; Anastasiadis, A.; Georgoulis, M.

    2013-09-01

    Elaborating a statistical approach to describe the spatiotemporally intermittent electric field structures formed inside a flaring solar active region, we investigate the efficiency of such structures in accelerating charged particles (electrons). The large-scale magnetic configuration in the solar atmosphere responds to the strong turbulent flows that convey perturbations across the active region by initiating avalanche-type processes. The resulting unstable structures correspond to small-scale dissipation regions hosting strong electric fields. Previous research on particle acceleration in strongly turbulent plasmas provides a general framework for addressing such a problem. This framework combines various electromagnetic field configurations obtained by magnetohydrodynamical (MHD) or cellular automata (CA) simulations, or by employing a statistical description of the field's strength and configuration with test particle simulations. Our objective is to complement previous work done on the subject. As in previous efforts, a set of three probability distribution functions describes our ad-hoc electromagnetic field configurations. In addition, we work on data-driven 3D magnetic field extrapolations. A collisional relativistic test-particle simulation traces each particle's guiding center within these configurations. We also find that an interplay between different electron populations (thermal/non-thermal, ambient/injected) in our simulations may also address, via a re-acceleration mechanism, the so called `number problem'. Using the simulated particle-energy distributions at different heights of the cylinder we test our results against observations, in the framework of the collisional thick target model (CTTM) of solar hard X-ray (HXR) emission. The above work is supported by the Hellenic National Space Weather Research Network (HNSWRN) via the THALIS Programme.

  15. Developing students' listening metacognitive strategies using online videotext self-dictation-generation learning activity

    Directory of Open Access Journals (Sweden)

    Ching Chang

    2014-03-01

    Full Text Available The study is based on the use of a flexible learning framework to help students improve information processes underlying strategy instruction in EFL listening. By exploiting the online videotext self-dictation-generation (video-SDG learning activity implemented on the YouTube caption manager platform, the learning cycle was emphasized to promote metacognitive listening development. Two theories were used to guide the online video-SDG learning activity: a student question-generation method and a metacognitive listening training model in a second language (L2. The study investigated how college students in the online video-SDG activity enhanced the use of listening strategies by developing metacognitive listening skills. With emphasis on the metacognitive instructional process, students could promote their listening comprehension of advertisement videos (AVs. Forty-eight students were recruited to participate in the study. Through data collected from the online learning platform, questionnaires, a focus-group interview, and pre- and post- achievement tests, the results revealed that the online video-SDG learning activity could effectively engage students in reflecting upon their perceptions of specific problems countered, listening strategy usages, and strategic knowledge exploited in the metacognitive instructional process. The importance of employing cost-effective online video-SGD learning activities is worthy of consideration in developing students’ metacognitive listening knowledge for enhancing EFL listening strategy instruction.

  16. Activation of sensory cortex by imagined genital stimulation: an fMRI analysis.

    Science.gov (United States)

    Wise, Nan J; Frangos, Eleni; Komisaruk, Barry R

    2016-01-01

    During the course of a previous study, our laboratory made a serendipitous finding that just thinking about genital stimulation resulted in brain activations that overlapped with, and differed from, those generated by physical genital stimulation. This study extends our previous findings by further characterizing how the brain differentially processes physical 'touch' stimulation and 'imagined' stimulation. Eleven healthy women (age range 29-74) participated in an fMRI study of the brain response to imagined or actual tactile stimulation of the nipple and clitoris. Two additional conditions - imagined dildo self-stimulation and imagined speculum stimulation - were included to characterize the effects of erotic versus non-erotic imagery. Imagined and tactile self-stimulation of the nipple and clitoris each activated the paracentral lobule (the genital region of the primary sensory cortex) and the secondary somatosensory cortex. Imagined self-stimulation of the clitoris and nipple resulted in greater activation of the frontal pole and orbital frontal cortex compared to tactile self-stimulation of these two bodily regions. Tactile self-stimulation of the clitoris and nipple activated the cerebellum, primary somatosensory cortex (hand region), and premotor cortex more than the imagined stimulation of these body regions. Imagining dildo stimulation generated extensive brain activation in the genital sensory cortex, secondary somatosensory cortex, hippocampus, amygdala, insula, nucleus accumbens, and medial prefrontal cortex, whereas imagining speculum stimulation generated only minimal activation. The present findings provide evidence of the potency of imagined stimulation of the genitals and that the following brain regions may participate in erogenous experience: primary and secondary sensory cortices, sensory-motor integration areas, limbic structures, and components of the 'reward system'. In addition, these results suggest a mechanism by which some individuals may

  17. Activation of sensory cortex by imagined genital stimulation: an fMRI analysis

    Directory of Open Access Journals (Sweden)

    Nan J. Wise

    2016-10-01

    Full Text Available Background: During the course of a previous study, our laboratory made a serendipitous finding that just thinking about genital stimulation resulted in brain activations that overlapped with, and differed from, those generated by physical genital stimulation. Objective: This study extends our previous findings by further characterizing how the brain differentially processes physical ‘touch’ stimulation and ‘imagined’ stimulation. Design: Eleven healthy women (age range 29–74 participated in an fMRI study of the brain response to imagined or actual tactile stimulation of the nipple and clitoris. Two additional conditions – imagined dildo self-stimulation and imagined speculum stimulation – were included to characterize the effects of erotic versus non-erotic imagery. Results: Imagined and tactile self-stimulation of the nipple and clitoris each activated the paracentral lobule (the genital region of the primary sensory cortex and the secondary somatosensory cortex. Imagined self-stimulation of the clitoris and nipple resulted in greater activation of the frontal pole and orbital frontal cortex compared to tactile self-stimulation of these two bodily regions. Tactile self-stimulation of the clitoris and nipple activated the cerebellum, primary somatosensory cortex (hand region, and premotor cortex more than the imagined stimulation of these body regions. Imagining dildo stimulation generated extensive brain activation in the genital sensory cortex, secondary somatosensory cortex, hippocampus, amygdala, insula, nucleus accumbens, and medial prefrontal cortex, whereas imagining speculum stimulation generated only minimal activation. Conclusion: The present findings provide evidence of the potency of imagined stimulation of the genitals and that the following brain regions may participate in erogenous experience: primary and secondary sensory cortices, sensory-motor integration areas, limbic structures, and components of the

  18. A study on biological activity of marine fungi from different habitats in coastal regions.

    Science.gov (United States)

    Zhou, Songlin; Wang, Min; Feng, Qi; Lin, Yingying; Zhao, Huange

    2016-01-01

    In recent years, marine fungi have become an important source of active marine natural products. Former researches are limited in habitats selection of fungi with bioactive compounds. In this paper were to measure antibacterial and antitumor cell activity for secondary metabolites of marine fungi, which were isolated from different habitats in coastal regions. 195 strains of marine fungi were isolated and purified from three different habitats. They biologically active experiment results showed that fungi isolation from the mangrove habitats had stronger antibacterial activity than others, and the stains isolated from the estuarial habitats had the least antibacterial activity. However, the strains separated from beach habitats strongly inhibited tumor cell proliferation in vitro, and fungi of mangrove forest habitats had the weakest activity of inhibiting tumor. Meanwhile, 195 fungal strains belonged to 46 families, 84 genera, 142 species and also showed 137 different types of activity combinations by analyzing the inhibitory activity of the metabolites fungi for 4 strains of pathogenic bacteria and B-16 cells. The study investigated the biological activity of marine fungi isolated from different habitats in Haikou coastal regions. The results help us to understand bioactive metabolites of marine fungi from different habitats, and how to selected biological activity fungi from various marine habitats effectively.

  19. Optimal policies for activated sludge treatment systems with multi effluent stream generation

    Directory of Open Access Journals (Sweden)

    Gouveia R.

    2000-01-01

    Full Text Available Most industrial processes generate liquid waste, which requires treatment prior to disposal. These processes are divided into sectors that generate effluents with time dependent characteristics. Each sector sends the effluent to wastewater treatment plants through pumping-stations. In general, activated sludge is the most suitable treatment and consists of equalization, aeration and settling tanks. During the treatment, there is an increase in the mass of microorganisms, which needs to be removed. Sludge removal represents the major operating costs for wastewater treatment plants. The objective of this work is to propose an optimization model to minimize sludge generation using a superstructure in which the streams from pumping-stations can be sent to the equalization tank. In addition, the aeration tank is divided into cells that can be fed in series and parallel. The model relies on mass balances, kinetic equations, and the resulting Nonlinear Programming problem generates the best operational strategy for the system feed streams with a high substrate removal. Reductions of up to 30 % can be achieved with the proposed strategy maintened BOD efficiency removal upper than 98 %.

  20. Clean Coal Technology: Region 4 Market Description, South Atlantic

    International Nuclear Information System (INIS)

    1993-09-01

    The Region 4 Market Description Summary provides information that can be used in developing an understanding of the potential markets for clean coal technologies (CCTs) in the South Atlantic Region. This region (which geographically is Federal Region 4) consists of the following eight states: Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee. In order to understand the potential market. A description is provided of the region's energy use, power generation capacity, and potential growth. Highlights of state government activities that could have a bearing on commercial deployment of CCTs are also presented. The potential markets characterized in this summary center on electric power generation by investor-owned, cooperative, and municipal electric utilities and involve planned new capacity additions and actions taken by utilities to comply with Phases I and II of the Clean Air Act Amendments (CAAA) of 1990. Regulations, policies, utility business strategies, and organizational changes that could impact the role of CCTs as a utility option are identified and discussed. The information used to develop the Region 4 Market Description is based mainly on an extensive review of plans and annual reports of 29 investor-owned, cooperative, and municipal coal-using electric utilities and public information on strategies and actions for complying with the CAAA of 1990

  1. Active sales promotion in urban regions; Aktive Verkaufsfoerderung in Verdichtungsgebieten

    Energy Technology Data Exchange (ETDEWEB)

    Becker, H.D. [Oeffentlichkeitsarbeit, Maingas AG, Frankfurt am Main (Germany)

    1995-03-01

    The first step in any worthwhile marketing strategy for urban regions is to make a survey of all real estates without a gas supply. The data stock thus obtained serves as a short, medium, and long-term basis for all further activity. It cal be used to set up yearly personnel and activity plans. The activities are rounded off by incentives in the form of conversion aids or financing offers and additional measures presented within a Full Service Package Defining clear aims makes it easier to evaluate the success of the activities. (orig.) [Deutsch] Der erste Schritt zu einer erfolgreichen Marktbearbeitung in Verdichtungsgebieten ist die Erhebung aller Liegenschaften ohne Gasversorgung. Der gewonnene Datenbestand dient kurz-, mittel- und langfristig als Grundlage aller Aktivitaeten. Eine Personal- und Aktivitaetenplanung kann jaehrlich daraus abgeleitet werden. Kaufanreize in Form von Umstellhilfen, Finanzierungsangeboten und zusaetzlichen Dienstleistungen im Rahmen eines Full-Service-Angebotes runden die Aktivitaeten ab. Die klare Vorgabe von Zielen erleichert die Erfolgskontrolle. (orig.)

  2. A Correlated Active Acoustic Leak Detection in a SFR Steam Generator

    International Nuclear Information System (INIS)

    Kim, Tae Joon; Jeong, Ji Young; Kim, Jong Man; Kim, Byung Ho; Kim, Yong Il

    2009-01-01

    The methods of acoustic leak detection are active acoustic leak detection and passive acoustic leak detection. The methods for passive acoustic leak detection are already established, but because our goal is development of passive acoustic leak detection for detecting a leakage range of small and micro leak rates, it is difficult detecting a leak in steam generator using this developed passive acoustic leak detection. Thus the acoustic leak detection system is required to be able to detect wide range of water leaks. From this view point we need to develop an active acoustic leak detection technology to be able to detect intermediate leak rates

  3. Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus

    International Nuclear Information System (INIS)

    Davis, M.G.; Kenney, S.C.; Kamine, J.; Pagano, J.S.; Huang, E.S.

    1987-01-01

    Almost all homosexual patients with acquired immunodeficiency syndrome are also actively infected with human cytomegalovirus (HCMV). The authors have hypothesized that an interaction between HCMV and human immunodeficiency virus (HIV), the agent that causes acquired immunodeficiency syndrome, may exist at a molecular level and contribute to the manifestations of HIV infection. In this report, they demonstrate that the immediate-early gene region of HCMV, in particular immediate-early region 2, trans-activates the expression of the bacterial gene chloramphenicol acetyltransferase that is fused to the HIV long terminal repeat and carried by plasmid pHIV-CAT. The HCMV immediate-early trans-activator increases the level of mRNA from the plamid pHIV-CAT. The sequences of HIV that are responsive to trans-activation by the HDMV immediate-early region are distinct from HIV sequences that are required for response to the HIV tat. The stimulation of HIV gene expression by HDMV gene functions could enhance the consequences of HIV infection in persons with previous or concurrent HCMV infection

  4. Organic geochemistry and petrology of oil source rocks, Carpathian Overthrust region, southeastern Poland - Implications for petroleum generation

    Science.gov (United States)

    Kruge, M.A.; Mastalerz, Maria; Solecki, A.; Stankiewicz, B.A.

    1996-01-01

    The organic mailer rich Oligocene Menilite black shales and mudstones are widely distributed in the Carpathian Overthrust region of southeastern Poland and have excellent hydrocarbon generation potential, according to TOC, Rock-Eval, and petrographic data. Extractable organic matter was characterized by an equable distribution of steranes by carbon number, by varying amounts of 28,30-dinor-hopane, 18??(H)-oleanane and by a distinctive group of C24 ring-A degraded triterpanes. The Menilite samples ranged in maturity from pre-generative to mid-oil window levels, with the most mature in the southeastern portion of the study area. Carpathian petroleum samples from Campanian Oligocene sandstone reservoirs were similar in biomarker composition to the Menilite rock extracts. Similarities in aliphatic and aromatic hydrocarbon distributions between petroleum asphaltene and source rock pyrolyzates provided further evidence genetically linking Menilite kerogens with Carpathian oils.

  5. High-fidelity MCNP modeling of a D-T neutron generator for active interrogation of special nuclear material

    International Nuclear Information System (INIS)

    Katalenich, Jeff; Flaska, Marek; Pozzi, Sara A.; Hartman, Michael R.

    2011-01-01

    Fast and robust methods for interrogation of special nuclear material (SNM) are of interest to many agencies and institutions in the United States. It is well known that passive interrogation methods are typically sufficient for plutonium identification because of a relatively high neutron production rate from 240 Pu . On the other hand, identification of shielded uranium requires active methods using neutron or photon sources . Deuterium-deuterium (2.45 MeV) and deuterium-tritium (14.1 MeV) neutron-generator sources have been previously tested and proven to be relatively reliable instruments for active interrogation of nuclear materials . In addition, the newest generators of this type are small enough for applications requiring portable interrogation systems. Active interrogation techniques using high-energy neutrons are being investigated as a method to detect hidden SNM in shielded containers . Due to the thickness of some containers, penetrating radiation such as high-energy neutrons can provide a potential means of probing shielded SNM. In an effort to develop the capability to assess the signal seen from various forms of shielded nuclear materials, University of Michigan Neutron Science Laboratory's D-T neutron generator and its shielding were accurately modeled in MCNP. The generator, while operating at nominal power, produces approximately 1x10 10 neutrons/s, a source intensity which requires a large amount of shielding to minimize the dose rates around the generator. For this reason, the existing shielding completely encompasses the generator and does not include beam ports. Therefore, several MCNP simulations were performed to estimate the yield of uncollided 14.1-MeV neutrons from the generator for active interrogation experiments. Beam port diameters of 5, 10, 15, 20, and 25 cm were modeled to assess the resulting neutron fluxes. The neutron flux outside the beam ports was estimated to be approximately 2x10 4 n/cm 2 s.

  6. Functional photoacoustic imaging to observe regional brain activation induced by cocaine hydrochloride

    Science.gov (United States)

    Jo, Janggun; Yang, Xinmai

    2011-09-01

    Photoacoustic microscopy (PAM) was used to detect small animal brain activation in response to drug abuse. Cocaine hydrochloride in saline solution was injected into the blood stream of Sprague Dawley rats through tail veins. The rat brain functional change in response to the injection of drug was then monitored by the PAM technique. Images in the coronal view of the rat brain at the locations of 1.2 and 3.4 mm posterior to bregma were obtained. The resulted photoacoustic (PA) images showed the regional changes in the blood volume. Additionally, the regional changes in blood oxygenation were also presented. The results demonstrated that PA imaging is capable of monitoring regional hemodynamic changes induced by drug abuse.

  7. A novel three-filament model of force generation in eccentric contraction of skeletal muscles.

    Directory of Open Access Journals (Sweden)

    Gudrun Schappacher-Tilp

    Full Text Available We propose and examine a three filament model of skeletal muscle force generation, thereby extending classical cross-bridge models by involving titin-actin interaction upon active force production. In regions with optimal actin-myosin overlap, the model does not alter energy and force predictions of cross-bridge models for isometric contractions. However, in contrast to cross-bridge models, the three filament model accurately predicts history-dependent force generation in half sarcomeres for eccentric and concentric contractions, and predicts the activation-dependent forces for stretches beyond actin-myosin filament overlap.

  8. Artificial E-region field-aligned plasma irregularities generated at pump frequencies near the second electron gyroharmonic

    Directory of Open Access Journals (Sweden)

    D. L. Hysell

    2009-07-01

    Full Text Available E region ionospheric modification experiments have been performed at HAARP using pump frequencies about 50 kHz above and below the second electron gyroharmonic frequency. Artificial E region field-aligned plasma density irregularities (FAIs were created and observed using the imaging coherent scatter radar near Homer, Alaska. Echoes from FAIs generated with pump frequencies above and below 2Ωe did not appear to differ significantly in experiments conducted on summer afternoons in 2008, and the resonance instability seemed to be at work in either case. We argue that upper hybrid wave trapping and resonance instability at pump frequencies below the second electron gyroharmonic frequency are permitted theoretically when the effects of finite parallel wavenumbers are considered. Echoes from a sporadic E layer were observed to be somewhat weaker when the pump frequency was 50 kHz below the second electron gyroharmonic frequency. This may indicate that finite parallel wavenumbers are inconsistent with wave trapping in thin sporadic E ionization layers.

  9. Two negative cis-regulatory regions involved in fruit-specific promoter activity from watermelon (Citrullus vulgaris S.).

    Science.gov (United States)

    Yin, Tao; Wu, Hanying; Zhang, Shanglong; Lu, Hongyu; Zhang, Lingxiao; Xu, Yong; Chen, Daming; Liu, Jingmei

    2009-01-01

    A 1.8 kb 5'-flanking region of the large subunit of ADP-glucose pyrophosphorylase, isolated from watermelon (Citrullus vulgaris S.), has fruit-specific promoter activity in transgenic tomato plants. Two negative regulatory regions, from -986 to -959 and from -472 to -424, were identified in this promoter region by fine deletion analyses. Removal of both regions led to constitutive expression in epidermal cells. Gain-of-function experiments showed that these two regions were sufficient to inhibit RFP (red fluorescent protein) expression in transformed epidermal cells when fused to the cauliflower mosaic virus (CaMV) 35S minimal promoter. Gel mobility shift experiments demonstrated the presence of leaf nuclear factors that interact with these two elements. A TCCAAAA motif was identified in these two regions, as well as one in the reverse orientation, which was confirmed to be a novel specific cis-element. A quantitative beta-glucuronidase (GUS) activity assay of stable transgenic tomato plants showed that the activities of chimeric promoters harbouring only one of the two cis-elements, or both, were approximately 10-fold higher in fruits than in leaves. These data confirm that the TCCAAAA motif functions as a fruit-specific element by inhibiting gene expression in leaves.

  10. Generation of knockout rabbits using transcription activator-like effector nucleases

    Directory of Open Access Journals (Sweden)

    Yu Wang

    2014-01-01

    Full Text Available Zinc-finger nucleases and transcription activator-like effector nucleases are novel gene-editing platforms contributing to redefine the boundaries of modern biological research. They are composed of a non-specific cleavage domain and a tailor made DNA-binding module, which enables a broad range of genetic modifications by inducing efficient DNA double-strand breaks at desired loci. Among other remarkable uses, these nucleases have been employed to produce gene knockouts in mid-size and large animals, such as rabbits and pigs, respectively. This approach is cost effective, relatively quick, and can produce invaluable models for human disease studies, biotechnology or agricultural purposes. Here we describe a protocol for the efficient generation of knockout rabbits using transcription activator-like effector nucleases, and a perspective of the field.

  11. Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate.

    Directory of Open Access Journals (Sweden)

    Roberto P Stock

    Full Text Available The toxicity of Loxosceles spider venom has been attributed to a rare enzyme, sphingomyelinase D, which transforms sphingomyelin to ceramide-1-phosphate. The bases of its inflammatory and dermonecrotic activity, however, remain unclear. In this work the effects of ceramide-1-phosphate on model membranes were studied both by in situ generation of this lipid using a recombinant sphingomyelinase D from the spider Loxosceles laeta and by pre-mixing it with sphingomyelin and cholesterol. The systems of choice were large unilamellar vesicles for bulk studies (enzyme kinetics, fluorescence spectroscopy and dynamic light scattering and giant unilamellar vesicles for fluorescence microscopy examination using a variety of fluorescent probes. The influence of membrane lateral structure on the kinetics of enzyme activity and the consequences of enzyme activity on the structure of target membranes containing sphingomyelin were examined. The findings indicate that: 1 ceramide-1-phosphate (particularly lauroyl ceramide-1-phosphate can be incorporated into sphingomyelin bilayers in a concentration-dependent manner and generates coexistence of liquid disordered/solid ordered domains, 2 the activity of sphingomyelinase D is clearly influenced by the supramolecular organization of its substrate in membranes and, 3 in situ ceramide-1-phosphate generation by enzymatic activity profoundly alters the lateral structure and morphology of the target membranes.

  12. Automated region selection for analysis of dynamic cardiac SPECT data

    Science.gov (United States)

    Di Bella, E. V. R.; Gullberg, G. T.; Barclay, A. B.; Eisner, R. L.

    1997-06-01

    Dynamic cardiac SPECT using Tc-99m labeled teboroxime can provide kinetic parameters (washin, washout) indicative of myocardial blood flow. A time-consuming and subjective step of the data analysis is drawing regions of interest to delineate blood pool and myocardial tissue regions. The time-activity curves of the regions are then used to estimate local kinetic parameters. In this work, the appropriate regions are found automatically, in a manner similar to that used for calculating maximum count circumferential profiles in conventional static cardiac studies. The drawbacks to applying standard static circumferential profile methods are the high noise level and high liver uptake common in dynamic teboroxime studies. Searching along each ray for maxima to locate the myocardium does not typically provide useful information. Here we propose an iterative scheme in which constraints are imposed on the radii searched along each ray. The constraints are based on the shape of the time-activity curves of the circumferential profile members and on an assumption that the short axis slices are approximately circular. The constraints eliminate outliers and help to reduce the effects of noise and liver activity. Kinetic parameter estimates from the automatically generated regions were comparable to estimates from manually selected regions in dynamic canine teboroxime studies.

  13. Antibacterial, Antioxidant, and Anticholinesterase Activities of Plant Seed Extracts from Brazilian Semiarid Region

    OpenAIRE

    Davi Felipe Farias; Terezinha Maria Souza; Martônio Ponte Viana; Bruno Marques Soares; Arcelina Pacheco Cunha; Ilka Maria Vasconcelos; Nágila Maria Pontes Silva Ricardo; Paulo Michel Pinheiro Ferreira; Vânia Maria Maciel Melo; Ana Fontenele Urano Carvalho

    2013-01-01

    The antimicrobial, antioxidant, and anticholinesterase activities of ethanolic seed extracts of twenty-one plant species from Brazilian semiarid region were investigated. The extracts were tested for antimicrobial activity against six bacteria strains and three yeasts. Six extracts presented activity against the Gram (−) organism Salmonella choleraesuis and the Gram (+) organisms Staphylococcus aureus and Bacillus subtilis. The MIC values ranged from 4.96 to 37.32 mg/mL. The Triplaris gardner...

  14. Active Ageing and Active Citizenship in Liguria: A Case Study

    Science.gov (United States)

    Palumbo, Mauro

    2014-01-01

    Liguria has the oldest age structure in Europe because of a low birth rate and long lifespans and therefore is a very interesting laboratory region in which to experiment with active ageing policies. The generations that are now approaching retirement hold a high level of personal and professional resources; so the "new" elderly people…

  15. Angiostatin generating capacity and anti-tumour effects of D-penicillamine and plasminogen activators.

    NARCIS (Netherlands)

    Groot-Besseling, R. de; Ruers, T.J.M.; Lamers-Elemans, I.L.; Maass, C.N.; Waal, R.M.W. de; Westphal, J.R.

    2006-01-01

    BACKGROUND: Upregulation of endogenous angiostatin levels may constitute a novel anti-angiogenic, and therefore anti-tumor therapy. In vitro, angiostatin generation is a two-step process, starting with the conversion of plasminogen to plasmin by plasminogen activators (PAs). Next, plasmin excises

  16. Cannabis cue-induced brain activation correlates with drug craving in limbic and visual salience regions: Preliminary results

    Science.gov (United States)

    Charboneau, Evonne J.; Dietrich, Mary S.; Park, Sohee; Cao, Aize; Watkins, Tristan J; Blackford, Jennifer U; Benningfield, Margaret M.; Martin, Peter R.; Buchowski, Maciej S.; Cowan, Ronald L.

    2013-01-01

    Craving is a major motivator underlying drug use and relapse but the neural correlates of cannabis craving are not well understood. This study sought to determine whether visual cannabis cues increase cannabis craving and whether cue-induced craving is associated with regional brain activation in cannabis-dependent individuals. Cannabis craving was assessed in 16 cannabis-dependent adult volunteers while they viewed cannabis cues during a functional MRI (fMRI) scan. The Marijuana Craving Questionnaire was administered immediately before and after each of three cannabis cue-exposure fMRI runs. FMRI blood-oxygenation-level-dependent (BOLD) signal intensity was determined in regions activated by cannabis cues to examine the relationship of regional brain activation to cannabis craving. Craving scores increased significantly following exposure to visual cannabis cues. Visual cues activated multiple brain regions, including inferior orbital frontal cortex, posterior cingulate gyrus, parahippocampal gyrus, hippocampus, amygdala, superior temporal pole, and occipital cortex. Craving scores at baseline and at the end of all three runs were significantly correlated with brain activation during the first fMRI run only, in the limbic system (including amygdala and hippocampus) and paralimbic system (superior temporal pole), and visual regions (occipital cortex). Cannabis cues increased craving in cannabis-dependent individuals and this increase was associated with activation in the limbic, paralimbic, and visual systems during the first fMRI run, but not subsequent fMRI runs. These results suggest that these regions may mediate visually cued aspects of drug craving. This study provides preliminary evidence for the neural basis of cue-induced cannabis craving and suggests possible neural targets for interventions targeted at treating cannabis dependence. PMID:24035535

  17. Effect of acetylcholine receptors on the pain-related electrical activities in the hippocampal CA3 region of morphine-addicted rats.

    Science.gov (United States)

    Li, Guan Zeng; Liu, Zhe Hui; Wei, XinYa; Zhao, Pan; Yang, Chun Xiao; Xu, Man Ying

    2015-07-01

    To determine the effect of acetylcholine (ACh), pilocarpine, and atropine on pain evoked responses of pain excited neurons (PEN) and pain inhibited neurons (PIN) in hippocampal CA3 region of morphine addicted rats. Female Wistar rats, weighing between 230-260 g were used in this study. Morphine addicted rats were generated by subcutaneous injection of increasing concentrations of morphine hydrochloride for six days. Trains of electrical impulses applied to the sciatic nerve were used as noxious stimulation and the evoked electrical activities of PEN or PIN in hippocampal CA3 area were recorded using extracellular electrophysiological recording techniques in hippocampal slices. The effect of acetylcholine receptor stimulation by ACh, the muscarinic agonist pilocarpine, and the muscarinic antagonist atropine on the pain evoked responses of pain related electrical activities was analyzed in hippocampal CA3 area of morphine addicted rats. Intra-CA3 microinjection of ACh (2 μg/1 μl) or pilocarpine (2 μg/1 μl) decreased the discharge frequency and prolonged the firing latency of PEN, but increased the discharge frequency and shortened the firing inhibitory duration (ID) of PIN. The intra-CA3 administration of atropine (0.5 μg/1 μl) produced opposite effect. The peak activity of cholinergic modulators was 2 to 4 min later in morphine addicted rats compared to peak activity previously observed in normal rats. ACh dependent modulation of noxious stimulation exists in hippocampal CA3 area of morphine addicted rats. Morphine treatment may shift the sensitivity of pain related neurons towards a delayed response to muscarinergic neurotransmission in hippocampal CA3 region.

  18. Effect of acetylcholine receptors on the pain-related electrical activities in the hippocampal CA3 region of morphine-addicted rats

    Directory of Open Access Journals (Sweden)

    Guan Zeng Li

    2015-07-01

    Full Text Available Objective(s:To determine the effect of acetylcholine (ACh, pilocarpine, and atropine on pain evoked responses of pain excited neurons (PEN and pain inhibited neurons (PIN in hippocampal CA3 region of morphine addicted rats. Materials and Methods:Female Wistar rats, weighing between 230-260 g were used in this study. Morphine addicted rats were generated by subcutaneous injection of increasing concentrations of morphine hydrochloride for six days. Trains of electrical impulses applied to the sciatic nerve were used as noxious stimulation and the evoked electrical activities of PEN or PIN in hippocampal CA3 area were recorded using extracellular electrophysiological recording techniques in hippocampal slices. The effect of acetylcholine receptor stimulation byACh, the muscarinic agonist pilocarpine, and the muscarinic antagonist atropine on the pain evoked responses of pain related electrical activities was analyzed in hippocampal CA3 area of morphine addicted rats. Results:Intra-CA3 microinjection of ACh (2 μg/1 μl or pilocarpine (2 μg/1 μl decreased the discharge frequency and prolonged the firing latency of PEN, but increased the discharge frequency and shortened the firing inhibitory duration (ID of PIN. The intra-CA3 administration of atropine (0.5 μg/1 μl produced opposite effect. The peak activity of cholinergic modulators was 2 to 4 min later in morphine addicted rats compared to peak activity previously observed in normal rats. Conclusion: ACh dependent modulation of noxious stimulation exists in hippocampal CA3 area of morphine addicted rats. Morphine treatment may shift the sensitivity of pain related neurons towards a delayed response to muscarinergic neurotransmission in hippocampal CA3 region.

  19. The brain as a dream state generator: an activation-synthesis hypothesis of the dream process.

    Science.gov (United States)

    Hobson, J A; McCarley, R W

    1977-12-01

    Recent research in the neurobiology of dreaming sleep provides new evidence for possible structural and functional substrates of formal aspects of the dream process. The data suggest that dreaming sleep is physiologically determined and shaped by a brain stem neuronal mechanism that can be modeled physiologically and mathematically. Formal features of the generator processes with strong implications for dream theory include periodicity and automaticity of forebrain activation, suggesting a preprogrammed neural basis for dream mentation in sleep; intense and sporadic activation of brain stem sensorimotor circuits including reticular, oculomotor, and vestibular neurons, possibly determining spatiotemporal aspects of dream imagery; and shifts in transmitter ratios, possibly accounting for dream amnesia. The authors suggest that the automatically activated forebrain synthesizes the dream by comparing information generated in specific brain stem circuits with information stored in memory.

  20. Generation of Active Bovine Terminal Deoxynucleotidyl Transferase (TdT in E.coli

    Directory of Open Access Journals (Sweden)

    Wee Liang Kuan

    2010-08-01

    Full Text Available A synthetic gene encoding bovine terminal deoxynucleotidyl transferase (TdT was generated, cloned into an expression vector and expressed in E.coli. The effects of altering culture and induction conditions on the nature of recombinant protein production were investigated. This led to the expression of active recombinant bovine TdT in E.coli. After purification and characterisation, the activity of the enzyme was assessed in a biological assay for apoptosis. The process described in this report enables the economical production of TdT for high throughput applications.

  1. Generation of Active Bovine Terminal Deoxynucleotidyl Transferase (TdT in E.coli

    Directory of Open Access Journals (Sweden)

    Wee Liang Kuan

    2010-01-01

    Full Text Available A synthetic gene encoding bovine terminal deoxynucleotidyl transferase (TdT was generated, cloned into an expression vector and expressed in E.coli. The effects of altering culture and induction conditions on the nature of recombinant protein production were investigated. This led to the expression of active recombinant bovine TdT in E.coli. After purification and characterisation, the activity of the enzyme was assessed in a biological assay for apoptosis. The process described in this report enables the economical production of TdT for high throughput applications.

  2. Active tectonics and earthquake potential of the Myanmar region

    Science.gov (United States)

    Wang, Yu; Sieh, Kerry; Tun, Soe Thura; Lai, Kuang-Yin; Myint, Than

    2014-04-01

    This paper describes geomorphologic evidence for the principal neotectonic features of Myanmar and its immediate surroundings. We combine this evidence with published structural, geodetic, and seismic data to present an overview of the active tectonic architecture of the region and its seismic potential. Three tectonic systems accommodate oblique collision of the Indian plate with Southeast Asia and extrusion of Asian territory around the eastern syntaxis of the Himalayan mountain range. Subduction and collision associated with the Sunda megathrust beneath and within the Indoburman range and Naga Hills accommodate most of the shortening across the transpressional plate boundary. The Sagaing fault system is the predominant locus of dextral motion associated with the northward translation of India. Left-lateral faults of the northern Shan Plateau, northern Laos, Thailand, and southern China facilitate extrusion of rocks around the eastern syntaxis of the Himalaya. All of these systems have produced major earthquakes within recorded history and continue to present major seismic hazards in the region.

  3. Multi-wavelength Observations of Solar Active Region NOAA 7154

    Science.gov (United States)

    Bruner, M. E.; Nitta, N. V.; Frank. Z. A.; Dame, L.; Suematsu, Y.

    2000-01-01

    We report on observations of a solar active region in May 1992 by the Solar Plasma Diagnostic Experiment (SPDE) in coordination with the Yohkoh satellite (producing soft X-ray images) and ground-based observatories (producing photospheric magnetograms and various filtergrams including those at the CN 3883 A line). The main focus is a study of the physical conditions of hot (T is approximately greater than 3 MK) coronal loops at their foot-points. The coronal part of the loops is fuzzy but what appear to be their footpoints in the transition region down to the photosphere are compact. Despite the morphological similarities, the footpoint emission at 10(exp 5) K is not quantitatively correlated with that at approximately 300 km above the tau (sub 5000) = 1 level, suggesting that the heat transport and therefore magnetic field topology in the intermediate layer is complicated. High resolution imaging observations with continuous temperature coverage are crucially needed.

  4. Generation of structurally novel short carotenoids and study of their biological activity

    DEFF Research Database (Denmark)

    Kim, Se Hyeuk; Kim, Moon S.; Lee, Bun Y.

    2016-01-01

    Recent research interest in phytochemicals has consistently driven the efforts in the metabolic engineering field toward microbial production of various carotenoids. In spite of systematic studies, the possibility of using C30 carotenoids as biologically functional compounds has not been explored...... thus far. Here, we generated 13 novel structures of C30 carotenoids and one C35 carotenoid, including acyclic, monocyclic, and bicyclic structures, through directed evolution and combinatorial biosynthesis, in Escherichia coli. Measurement of radical scavenging activity of various C30 carotenoid...... structures revealed that acyclic C30 carotenoids showed higher radical scavenging activity than did DL-atocopherol. We could assume high potential biological activity of the novel structures of C30 carotenoids as well, based on the neuronal differentiation activity observed for the monocyclic C30 carotenoid...

  5. Evaluating Promotional Activities in an Online Two-Sided Market of User-Generated Content

    OpenAIRE

    Paulo Albuquerque; Polykarpos Pavlidis; Udi Chatow; Kay-Yut Chen; Zainab Jamal

    2012-01-01

    We measure the value of promotional activities and referrals by content creators to an online platform of user-generated content. To do so, we develop a modeling approach that explains individual-level choices of visiting the platform, creating, and purchasing content as a function of consumer characteristics and marketing activities, allowing for the possibility of interdependence of decisions within and across users. Empirically, we apply our model to Hewlett-Packard's (HP) print-on-demand ...

  6. Modulation of Na+/K+ ATPase Activity by Hydrogen Peroxide Generated through Heme in L. amazonensis.

    Directory of Open Access Journals (Sweden)

    Nathália Rocco-Machado

    Full Text Available Leishmania amazonensis is a protozoan parasite that occurs in many areas of Brazil and causes skin lesions. Using this parasite, our group showed the activation of Na+/K+ ATPase through a signaling cascade that involves the presence of heme and protein kinase C (PKC activity. Heme is an important biomolecule that has pro-oxidant activity and signaling capacity. Reactive oxygen species (ROS can act as second messengers, which are required in various signaling cascades. Our goal in this work is to investigate the role of hydrogen peroxide (H2O2 generated in the presence of heme in the Na+/K+ ATPase activity of L. amazonensis. Our results show that increasing concentrations of heme stimulates the production of H2O2 in a dose-dependent manner until a concentration of 2.5 μM heme. To confirm that the effect of heme on the Na+/K+ ATPase is through the generation of H2O2, we measured enzyme activity using increasing concentrations of H2O2 and, as expected, the activity increased in a dose-dependent manner until a concentration of 0.1 μM H2O2. To investigate the role of PKC in this signaling pathway, we observed the production of H2O2 in the presence of its activator phorbol 12-myristate 13-acetate (PMA and its inhibitor calphostin C. Both showed no effect on the generation of H2O2. Furthermore, we found that PKC activity is increased in the presence of H2O2, and that in the presence of calphostin C, H2O2 is unable to activate the Na+/K+ ATPase. 100 μM of Mito-TEMPO was capable of abolishing the stimulatory effect of heme on Na+/K+ ATPase activity, indicating that mitochondria might be the source of the hydrogen peroxide production induced by heme. The modulation of L. amazonensis Na+/K+ ATPase by H2O2 opens new possibilities for understanding the signaling pathways of this parasite.

  7. Regional development and regional policy

    OpenAIRE

    Šabić, Dejan; Vujadinović, Snežana

    2017-01-01

    Economic polarization is a process that is present at global, national and regional level. Economic activity is extremely spatially concentrated. Cities and developed regions use the agglomeration effect to attract labor and capital, thus achieving more favorable economic conditions than the agrarian region. Scientific research and European experiences over the past decades have contributed to the discrepancy among theorists about the causes and consequences of regional inequalities. Regional...

  8. [Effects of altitudes on soil microbial biomass and enzyme activity in alpine-gorge regions.

    Science.gov (United States)

    Cao, Rui; Wu, Fu Zhong; Yang, Wan Qin; Xu, Zhen Feng; Tani, Bo; Wang, Bin; Li, Jun; Chang, Chen Hui

    2016-04-22

    In order to understand the variations of soil microbial biomass and soil enzyme activities with the change of altitude, a field incubation was conducted in dry valley, ecotone between dry valley and mountain forest, subalpine coniferous forest, alpine forest and alpine meadow from 1563 m to 3994 m of altitude in the alpine-gorge region of western Sichuan. The microbial biomass carbon and nitrogen, and the activities of invertase, urease and acid phosphorus were measured in both soil organic layer and mineral soil layer. Both the soil microbial biomass and soil enzyme activities showed the similar tendency in soil organic layer. They increased from 2158 m to 3028 m, then decreased to the lowest value at 3593 m, and thereafter increased until 3994 m in the alpine-gorge region. In contrast, the soil microbial biomass and soil enzyme activities in mineral soil layer showed the trends as, the subalpine forest at 3028 m > alpine meadow at 3994 m > montane forest ecotone at 2158 m > alpine forest at 3593 m > dry valley at 1563 m. Regardless of altitudes, soil microbial biomass and soil enzyme activities were significantly higher in soil organic layer than in mineral soil layer. The soil microbial biomass was significantly positively correlated with the activities of the measured soil enzymes. Moreover, both the soil microbial biomass and soil enzyme activities were significantly positively correlated with soil water content, organic carbon, and total nitrogen. The activity of soil invertase was significantly positively correlated with soil phosphorus content, and the soil acid phosphatase was so with soil phosphorus content and soil temperature. In brief, changes in vegetation and other environmental factors resulting from altitude change might have strong effects on soil biochemical properties in the alpine-gorge region.

  9. The activL® Artificial Disc: a next-generation motion-preserving implant for chronic lumbar discogenic pain

    Science.gov (United States)

    Yue, James J; Garcia, Rolando; Miller, Larry E

    2016-01-01

    Degeneration of the lumbar intervertebral discs is a leading cause of chronic low back pain in adults. Treatment options for patients with chronic lumbar discogenic pain unresponsive to conservative management include total disc replacement (TDR) or lumbar fusion. Until recently, only two lumbar TDRs had been approved by the US Food and Drug Administration − the Charité Artificial Disc in 2004 and the ProDisc-L Total Disc Replacement in 2006. In June 2015, a next-generation lumbar TDR received Food and Drug Administration approval − the activL® Artificial Disc (Aesculap Implant Systems). Compared to previous-generation lumbar TDRs, the activL® Artificial Disc incorporates specific design enhancements that result in a more precise anatomical match and allow a range of motion that better mimics the healthy spine. The results of mechanical and clinical studies demonstrate that the activL® Artificial Disc results in improved mechanical and clinical outcomes versus earlier-generation artificial discs and compares favorably to lumbar fusion. The purpose of this report is to describe the activL® Artificial Disc including implant characteristics, intended use, surgical technique, postoperative care, mechanical testing, and clinical experience to date. PMID:27274317

  10. Generation of 3D templates of active sites of proteins with rigid prosthetic groups

    OpenAIRE

    Nebel, Jean-Christophe

    2006-01-01

    MOTIVATION: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein structures is an exciting prospect: active sites could be better understood, protein functions and protein 3D structures could be predicted more accurately. Although patterns can already be generated at the fold and topological levels, no system produces high-resolution 3D patterns including atom and cavity positions. To a...

  11. Suppression of in vitro cell-mediated lympholysis generation by alloactivated lymphocytes. Examination of radioresistant suppressive activity

    International Nuclear Information System (INIS)

    Orosz, C.G.; Ferguson, R.M.

    1986-01-01

    We investigated the radioresistant (1000 rads) suppression of CML generation mediated by alloactivated murine splenocytes. Suppressive cells were generated in MLCs by stimulation of (A X 6R)F1 splenocytes with irradiated C57BL/10 splenocytes. Suppressive cells could lyse targets bearing H-2b alloantigens, but would not lyse parental B10.T(6R) or B10.A targets. Suppressive activity was detected by including the alloactivated (A X 6R)F1 cells in B10.T(6R) anti-B10.A(1R) MLCs. Relative to the suppressive (A X 6R)F1 cells, the B10.A(1R) lymphocytes display both parental and suppressor-inducing alloantigens. In the absence of a suppressive population, B10.A(1R) stimulators cause B10.T(6R) splenocytes to generate cytolytic activity specific for both H-2Db (suppressor-inducing) and H-2Kk (suppressor-borne) target determinants. The irradiated, alloactivated (A X 6R)F1 cells decrease the H-2Db-specific CML generated in this system, thus mediating apparent antigen-specific suppression. However, cytolytic activity concomitantly generated in the same culture against the unrelated H-2Kk target determinants is similarly reduced by the (A X 6R)F1 cells. Thus, radioresistant suppression by alloactivated splenocytes is not necessarily antigen-specific. The irradiated (A X 6R)F1 cells would not suppress the generation of H-2Kk-specific CTL in B10.T(6R) anti-B10.A MLCs. Hence, the irradiated (A X 6R)F1 cells can impede CML generation against third-party alloantigens if, and only if, those alloantigens are coexpressed with suppressor-inducing alloantigens on the stimulator cells in suppressed MLCs. Similar results were also obtained using a different histoincompatible lymphocyte combination

  12. Socioeconomic and regional differences in active transportation in Brazil.

    Science.gov (United States)

    Sá, Thiago Hérick de; Pereira, Rafael Henrique Moraes; Duran, Ana Clara; Monteiro, Carlos Augusto

    2016-06-27

    To present national estimates regarding walking or cycling for commuting in Brazil and in 10 metropolitan regions. By using data from the Health section of 2008's Pesquisa Nacional por Amostra de Domicílio (Brazil's National Household Sample Survey), we estimated how often employed people walk or cycle to work, disaggregating our results by sex, age range, education level, household monthly income per capita, urban or rural address, metropolitan regions, and macro-regions in Brazil. Furthermore, we estimated the distribution of this same frequency according to quintiles of household monthly income per capita in each metropolitan region of the country. A third of the employed men and women walk or cycle from home to work in Brazil. For both sexes, this share decreases as income and education levels rise, and it is higher among younger individuals, especially among those living in rural areas and in the Northeast region of the country. Depending on the metropolitan region, the practice of active transportation is two to five times more frequent among low-income individuals than among high-income individuals. Walking or cycling to work in Brazil is most frequent among low-income individuals and the ones living in less economically developed areas. Active transportation evaluation in Brazil provides important information for public health and urban mobility policy-making. Apresentar estimativas nacionais sobre o deslocamento a pé ou de bicicleta no trajeto casa-trabalho no Brasil e em 10 de suas regiões metropolitanas. Utilizando dados do Suplemento sobre Saúde da Pesquisa Nacional por Amostra de Domicílios de 2008, estimamos a frequência de pessoas empregadas que se deslocam a pé ou de bicicleta no trajeto casa-trabalho estratificada por sexo, e segundo faixa etária, escolaridade, renda domiciliar per capita, residência em área urbana ou rural, regiões metropolitanas e macrorregiões do país. Adicionalmente, estimamos a distribuição da mesma frequ

  13. A Space Weather mission concept: Observatories of the Solar Corona and Active Regions (OSCAR)

    DEFF Research Database (Denmark)

    Strugarek, Antoine; Janitzek, Nils; Lee, Arrow

    2015-01-01

    advancements in the field of solar physics, improvements of the current CME prediction models, and provide data for reliable space weather forecasting. These objectives are achieved by utilising two spacecraft with identical instrumentation, located at a heliocentric orbital distance of 1 AU from the Sun......Coronal Mass Ejections (CMEs) and Corotating Interaction Regions (CIRs) are major sources of magnetic storms on Earth and are therefore considered to be the most dangerous space weather events. The Observatories of Solar Corona and Active Regions (OSCAR) mission is designed to identify the 3D...... structure of coronal loops and to study the trigger mechanisms of CMEs in solar Active Regions (ARs) as well as their evolution and propagation processes in the inner heliosphere. It also aims to provide monitoring and forecasting of geo-effective CMEs and CIRs. OSCAR would contribute to significant...

  14. Cortical language activation in aphasia: a functional MRI study

    International Nuclear Information System (INIS)

    Xu Xiaojun; Zhang Minming; Shang Desheng; Wang Qidong; Luo Benyan

    2004-01-01

    Objective: To investigate the differences of the underlying neural basis of language processing between normal subjects and aphasics, and to study the feasibility for functional magnetic resonance imaging (fMRI) in examining the cortical language activation in clinical aphasics. Methods: fMRI was used to map language network in 6 normal subjects and 3 patients with aphasia who were in the stage of recovery from acute stroke. The participants performed word generation task during fMRI scanning, which measured the signal changes associated with regional neural activity induced by the task. These signal changes were processed to statistically generate the activation map that represented the language area. Results: In normal subjects, a distributed language network was activated. Activations were present in the frontal, temporal, parietal and occipital regions in normal group. In the patient group, however, no activation was showed in the left inferior frontal gyrus whether or not the patient had lesion in the left frontal lobe. Two patients showed activations in some right hemisphere regions where no activation appeared in normal subjects. Conclusion: The remote effect of focal lesion and functional redistribution or reorganization was found in aphasic patients. fMRI was useful in evaluating the language function in aphasic patients. (authors)

  15. Steps being taken to resolve questions on natural gas use for power generation in the New England region

    International Nuclear Information System (INIS)

    Gulick, C.

    1995-01-01

    Steps being taken to resolve questions on natural gas use for power generation in the New England Region are outlined. The following topics are discussed: bridging the gap, gas/electric discussion group, energy consumption by fuel, NEPOOL energy mix forecast, the players and their needs, pipelines serving New England, evaluation of pipeline reliability, industry survey, summary of survey conclusions, communications, operational differences, recommended red alert information sequence, handling a crisis, and major accomplishments to date

  16. Common brain regions underlying different arithmetic operations as revealed by conjunct fMRI-BOLD activation.

    Science.gov (United States)

    Fehr, Thorsten; Code, Chris; Herrmann, Manfred

    2007-10-03

    The issue of how and where arithmetic operations are represented in the brain has been addressed in numerous studies. Lesion studies suggest that a network of different brain areas are involved in mental calculation. Neuroimaging studies have reported inferior parietal and lateral frontal activations during mental arithmetic using tasks of different complexities and using different operators (addition, subtraction, etc.). Indeed, it has been difficult to compare brain activation across studies because of the variety of different operators and different presentation modalities used. The present experiment examined fMRI-BOLD activity in participants during calculation tasks entailing different arithmetic operations -- addition, subtraction, multiplication and division -- of different complexities. Functional imaging data revealed a common activation pattern comprising right precuneus, left and right middle and superior frontal regions during all arithmetic operations. All other regional activations were operation specific and distributed in prominently frontal, parietal and central regions when contrasting complex and simple calculation tasks. The present results largely confirm former studies suggesting that activation patterns due to mental arithmetic appear to reflect a basic anatomical substrate of working memory, numerical knowledge and processing based on finger counting, and derived from a network originally related to finger movement. We emphasize that in mental arithmetic research different arithmetic operations should always be examined and discussed independently of each other in order to avoid invalid generalizations on arithmetics and involved brain areas.

  17. Simultaneous SMM flat crystal spectrometer and Very Large Array observations of solar active regions

    Science.gov (United States)

    Lang, Kenneth R.; Willson, Robert F.; Smith, Kermit L.; Strong, Keith T.

    1987-01-01

    High-resolution images of the quiescent emission from two solar active regions at 20 cm (VLA) and soft X-ray (SMM FCS) wavelengths are compared. There are regions where the X-ray coronal loops have been completely imaged at 20 cm wavelength. In other regions, the X-ray radiation was detected without detectable 20 cm radiation, and vice versa. The X-ray data were used to infer average electron temperatures of about 3-million K and average electron densities of about 2.5 x 10 to the 9th/cu cm for the X-ray emitting plasma in the two active regions. The thermal bremsstrahlung of the X-ray emitting plasma is optically thin at 20 cm wavelength. The 20 cm brightness temperatures were always less than T(e), which is consistent with optically thin bremsstrahlung. The low T(B) can be explained if a higher, cooler plasma covers the hotter X-ray emitting plasma. Thermal gyroresonance radiation must account for the intense 20 cm radiation near and above sunspots where no X-ray radiation is detected.

  18. Scheme of fault tectonic and tectonic activity manifestation in the region of the Crimea nuclear power plant construction

    International Nuclear Information System (INIS)

    Pasynkov, A.L.

    1989-01-01

    Characteristic of fault tectonics and tectonic activity manifestation in the region of the Crimea nuclear power plant construction is presented. Mosaic-block structure of the area, predetermined by the development of diagonal systems of activated tectonic dislocations with different displacement amplitudes and different stratigraphic ranges of manifestation, was established. Strained-stressed state of the region is determined by the presence of the South-Azov zone of deep fault and Krasnogorsk-Samarlinks fault system. The presented scheme can be used as tectonic basis of seismogenic activity of the region

  19. Altered regional and circuit resting-state activity associated with unilateral hearing loss.

    Directory of Open Access Journals (Sweden)

    Xingchao Wang

    Full Text Available The deprivation of sensory input after hearing damage results in functional reorganization of the brain including cross-modal plasticity in the sensory cortex and changes in cognitive processing. However, it remains unclear whether partial deprivation from unilateral auditory loss (UHL would similarly affect the neural circuitry of cognitive processes in addition to the functional organization of sensory cortex. Here, we used resting-state functional magnetic resonance imaging to investigate intrinsic activity in 34 participants with UHL from acoustic neuroma in comparison with 22 matched normal controls. In sensory regions, we found decreased regional homogeneity (ReHo in the bilateral calcarine cortices in UHL. However, there was an increase of ReHo in the right anterior insular cortex (rAI, the key node of cognitive control network (CCN and multimodal sensory integration, as well as in the left parahippocampal cortex (lPHC, a key node in the default mode network (DMN. Moreover, seed-based resting-state functional connectivity analysis showed an enhanced relationship between rAI and several key regions of the DMN. Meanwhile, lPHC showed more negative relationship with components in the CCN and greater positive relationship in the DMN. Such reorganizations of functional connectivity within the DMN and between the DMN and CCN were confirmed by a graph theory analysis. These results suggest that unilateral sensory input damage not only alters the activity of the sensory areas but also reshapes the regional and circuit functional organization of the cognitive control network.

  20. Observations of vector magnetic fields in flaring active regions

    Science.gov (United States)

    Chen, Jimin; Wang, Haimin; Zirin, Harold; Ai, Guoxiang

    1994-01-01

    We present vector magnetograph data of 6 active regions, all of which produced major flares. Of the 20 M-class (or above) flares, 7 satisfy the flare conditions prescribed by Hagyard (high shear and strong transverse fields). Strong photospheric shear, however, is not necessarily a condition for a flare. We find an increase in the shear for two flares, a 6-deg shear increase along the neutral line after a X-2 flare and a 13-deg increase after a M-1.9 flare. For other flares, we did not detect substantial shear changes.

  1. Planning Mechanisms for Regional Electric Power Supply System Development

    Directory of Open Access Journals (Sweden)

    Evgeniy Anatolyevich Malyshev

    2015-12-01

    Full Text Available Key problems of the regional electric power supply systems are examined. These problems result from a lack of regulated interaction mechanisms for uniting the different entities’ resources aimed at the realization of investment activities. One of the main problems of the power supply industry is physical and moral aging of both generating and networking equipment. In the article, the necessity of management system formation to control the development of power sector has been proved. The deficiencies of the modern investment procedure in power companies are described. The absence of continuity between the regional and local strategic planning documents and investment planning of a power company has been found out. The possibility to develop a new mechanism for attracting investment has been proposed. The regulation of joint activities to implement the development program for the regional power supply industry has been proposed. The management system to develop the Russian power industry has been proposed. The comparative analysis of generating capacity development mechanisms has been carried out, such as capacity supply agreement (CSA, investment support mechanism (ISM, and long-term power market (LPM. The interaction procedure of the planning of the power supply infrastructure development has been described. The mechanism connecting the state sectoral and regional planning and corporate planning of power supply infrastructure development has been proposed. The regional aspects of industrial policy and its legislative support have been considered. To successfully implement the public-private-partnership (PPP projects, it is necessary to create the effective PPP model within the federal and regional legislation framework; to develop the financial model providing the recoverability of investments; to provide a mutually beneficial cooperation between executive bodies and private investors. The possibility to apply the PPP mechanism for regional

  2. Routes to the past: neural substrates of direct and generative autobiographical memory retrieval.