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Sample records for activator spa influences

  1. Spa47 is an oligomerization-activated type three secretion system (T3SS) ATPase from Shigella flexneri.

    Science.gov (United States)

    Burgess, Jamie L; Jones, Heather B; Kumar, Prashant; Toth, Ronald T; Middaugh, C Russell; Antony, Edwin; Dickenson, Nicholas E

    2016-05-01

    Gram-negative pathogens often use conserved type three secretion systems (T3SS) for virulence. The Shigella type three secretion apparatus (T3SA) penetrates the host cell membrane and provides a unidirectional conduit for injection of effectors into host cells. The protein Spa47 localizes to the base of the apparatus and is speculated to be an ATPase that provides the energy for T3SA formation and secretion. Here, we developed an expression and purification protocol, producing active Spa47 and providing the first direct evidence that Spa47 is a bona fide ATPase. Additionally, size exclusion chromatography and analytical ultracentrifugation identified multiple oligomeric species of Spa47 with the largest greater than 8 fold more active for ATP hydrolysis than the monomer. An ATPase inactive Spa47 point mutant was then engineered by targeting a conserved Lysine within the predicted Walker A motif of Spa47. Interestingly, the mutant maintained a similar oligomerization pattern as active Spa47, but was unable to restore invasion phenotype when used to complement a spa47 null S. flexneri strain. Together, these results identify Spa47 as a Shigella T3SS ATPase and suggest that its activity is linked to oligomerization, perhaps as a regulatory mechanism as seen in some related pathogens. Additionally, Spa47 catalyzed ATP hydrolysis appears to be essential for host cell invasion, providing a strong platform for additional studies dissecting its role in virulence and providing an attractive target for anti-infective agents. © 2016 The Protein Society.

  2. THE INFLUENCE OF CROSS-TRAINING DUE TO SPA TREATMENT IN CURRING FUNCTIONAL NEUROTIC DISORDERS

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    Rade Stefanović

    2006-06-01

    Full Text Available Modern civilization moves to endless automation and mechanization. This fact, in one hand, has positive effect on increase of life standard, but also carries its own risks and threats of mankind. Axelberg, famous academician, makes an interesting remark that only a hundred years ago man did 96 % of his work by himself, while today most manufacturing processes are 100% automated. Stress, lack of physical activity and bad food regime are canses of organic damages of cardiopulmonary system. Latest research, conducted in many countries, shows that for proper functioning of every organism the minimum of moving is necessary.Term neurosis was introduced in medical literature by Scottish doctor W. Cullen in 1777. By that term were considered different clinical appearances which are believed neurotic todey, but also the phenomena today considered as psychosomatic disorders of character and behavior. Pavlov’s reflexive theory is basic in treatment of some types of neurossis’ during spa treatments in Nerečinska Banja. It usually starts at the beginning of May and ends in October, but sometimes if weather is nice, it can last until the middle of November. The treatment cure last tventy-one day, doesn’t include medicaments, but only spa water, baths and massage.

  3. Measurements of radon activity concentrations in air at Niska spa

    International Nuclear Information System (INIS)

    Adrovic, F.; Vuckovic, B.; Ninkovic, M.

    2004-01-01

    Radon activity concentrations in air were measured in the recreational-tourist center of Niska Banja. Alpha Guard PQ 2000/ MC50 instrumentation (Genitron instruments, Frankfurt) was used. The observed indoor radon concentrations in the air of the Radon Hotel pool lay within the range of 0.980-1.908 kBq/m 3 and were directly dependent on the exhalation of radon from thermomineral waters. Radon concentrations were also measured outdoors, at locations for capping thermomineral water, as well as at locations for draining used water from the Radon Hotel pool. Outdoor radon concentrations as high as over 500 Bq/m 3 were observed. Gamma dose rates were measured in parallel and found to lie within the range of 72-420 nSv/h. The gamma doses correlated well with the observed radon levels. The largest gamma dose rates in air were measured in the pool of Radon Hotel and at the site where this thermomineral water is being capped

  4. Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation.

    Science.gov (United States)

    Burgess, Jamie L; Burgess, R Alan; Morales, Yalemi; Bouvang, Jenna M; Johnson, Sean J; Dickenson, Nicholas E

    2016-12-09

    Like many Gram-negative pathogens, Shigella rely on a complex type III secretion system (T3SS) to inject effector proteins into host cells, take over host functions, and ultimately establish infection. Despite these critical roles, the energetics and regulatory mechanisms controlling the T3SS and pathogen virulence remain largely unclear. In this study, we present a series of high resolution crystal structures of Spa47 and use the structures to model an activated Spa47 oligomer, finding that ATP hydrolysis may be supported by specific side chain contributions from adjacent protomers within the complex. Follow-up mutagenesis experiments targeting the predicted active site residues validate the oligomeric model and determined that each of the tested residues are essential for Spa47 ATPase activity, although they are not directly responsible for stable oligomer formation. Although N-terminal domain truncation was necessary for crystal formation, it resulted in strictly monomeric Spa47 that is unable to hydrolyze ATP, despite maintaining the canonical ATPase core structure and active site residues. Coupled with studies of ATPase inactive full-length Spa47 point mutants, we find that Spa47 oligomerization and ATP hydrolysis are needed for complete T3SS apparatus formation, a proper translocator secretion profile, and Shigella virulence. This work represents the first structure-function characterization of Spa47, uniquely complementing the multitude of included Shigella T3SS phenotype assays and providing a more complete understanding of T3SS ATPase-mediated pathogen virulence. Additionally, these findings provide a strong platform for follow-up studies evaluating regulation of Spa47 oligomerization in vivo as a much needed means of treating and perhaps preventing shigellosis. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  5. Structural and Biochemical Characterization of Spa47 Provides Mechanistic Insight into Type III Secretion System ATPase Activation and Shigella Virulence Regulation*

    Science.gov (United States)

    Burgess, Jamie L.; Burgess, R. Alan; Morales, Yalemi; Bouvang, Jenna M.; Johnson, Sean J.; Dickenson, Nicholas E.

    2016-01-01

    Like many Gram-negative pathogens, Shigella rely on a complex type III secretion system (T3SS) to inject effector proteins into host cells, take over host functions, and ultimately establish infection. Despite these critical roles, the energetics and regulatory mechanisms controlling the T3SS and pathogen virulence remain largely unclear. In this study, we present a series of high resolution crystal structures of Spa47 and use the structures to model an activated Spa47 oligomer, finding that ATP hydrolysis may be supported by specific side chain contributions from adjacent protomers within the complex. Follow-up mutagenesis experiments targeting the predicted active site residues validate the oligomeric model and determined that each of the tested residues are essential for Spa47 ATPase activity, although they are not directly responsible for stable oligomer formation. Although N-terminal domain truncation was necessary for crystal formation, it resulted in strictly monomeric Spa47 that is unable to hydrolyze ATP, despite maintaining the canonical ATPase core structure and active site residues. Coupled with studies of ATPase inactive full-length Spa47 point mutants, we find that Spa47 oligomerization and ATP hydrolysis are needed for complete T3SS apparatus formation, a proper translocator secretion profile, and Shigella virulence. This work represents the first structure-function characterization of Spa47, uniquely complementing the multitude of included Shigella T3SS phenotype assays and providing a more complete understanding of T3SS ATPase-mediated pathogen virulence. Additionally, these findings provide a strong platform for follow-up studies evaluating regulation of Spa47 oligomerization in vivo as a much needed means of treating and perhaps preventing shigellosis. PMID:27770024

  6. MxiN Differentially Regulates Monomeric and Oligomeric Species of the Shigella Type Three Secretion System ATPase Spa47.

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    Case, Heather B; Dickenson, Nicholas E

    2018-04-17

    Shigella rely entirely on the action of a single type three secretion system (T3SS) to support cellular invasion of colonic epithelial cells and to circumvent host immune responses. The ATPase Spa47 resides at the base of the Shigella needle-like type three secretion apparatus (T3SA), supporting protein secretion through the apparatus and providing a likely means for native virulence regulation by Shigella and a much needed target for non-antibiotic therapeutics to treat Shigella infections. Here, we show that MxiN is a differential regulator of Spa47 and that its regulatory impact is determined by the oligomeric state of the Spa47 ATPase, with which it interacts. In vitro and in vivo characterization shows that interaction of MxiN with Spa47 requires the six N-terminal residues of Spa47 that are also necessary for stable Spa47 oligomer formation and activation. This interaction with MxiN negatively influences the activity of Spa47 oligomers while upregulating the ATPase activity of monomeric Spa47. Detailed kinetic analyses of monomeric and oligomeric Spa47 in the presence and absence of MxiN uncover additional mechanistic insights into the regulation of Spa47 by MxiN, suggesting that the MxiN/Spa47 species resulting from interaction with monomeric and oligomeric Spa47 are functionally distinct and that both could be involved in Shigella T3SS regulation. Uncovering regulation of Spa47 by MxiN addresses an important gap in the current understanding of how Shigella controls T3SA activity and provides the first description of differential T3SS ATPase regulation by a native T3SS protein.

  7. MANAGEMENT AND DEVELOPMENT POSSIBILITIES FOR SPA TOURISM IN SERBIA

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    Nemanja BERBER

    2010-06-01

    Full Text Available Two forms of tourism, which are represented to a large extent in the world, are spa and wellness tourism. In Serbia, spa and wellness tourism are not sufficiently used, although there are excellent conditions. During twenty century the state was paying more attention and money on the sea and river tourism. However, the separation of Serbia and Montenegro in two independent counties had left Serbia without an entrance to the Adriatic Sea, so development of other tourist products and destinations became an imperative for survival and existence in the tourist map of Europe and the world. The paper presents the basic aims and policies of development of spa tourism in Serbia and data obtained in the survey regarding quality of services provided in some spa towns in Serbia. Based on the results to which the research occurred, authors wished to point out main activities and tasks that the state uses in creating a development strategy of spa tourism, the programs that have already been taken, so as the influence of the economic crisis to spa tourism.

  8. Diverse modulation of spa transcription by cell wall active antibiotics in Staphylococcus aureus

    DEFF Research Database (Denmark)

    Nielsen, Lene Nørby; Roggenbuck, Michael; Haaber, Jakob Krause

    2012-01-01

    ABSTRACT: BACKGROUND: The aim of this study was to investigate the effect of various classes of clinically relevant antibiotics at sub-lethal concentrations on virulence gene expression and biofilm formation in Staphylococcus aureus. FINDINGS: LacZ promoter fusions of genes related to staphylococ......ABSTRACT: BACKGROUND: The aim of this study was to investigate the effect of various classes of clinically relevant antibiotics at sub-lethal concentrations on virulence gene expression and biofilm formation in Staphylococcus aureus. FINDINGS: LacZ promoter fusions of genes related...... to staphylococcal virulence were used to monitor the effects of antibiotics on gene expression in a disc diffusion assay. The selected genes were hla and spa encoding alpha-hemolysin and Protein A, respectively and RNAIII, the effector molecule of the agr quorum sensing system. The results were confirmed...... by quantitative real-time PCR. Additionally, we monitored the effect of subinhibitory concentrations of antibiotics on the ability of S. aureus to form biofilm in a microtiter plate assay. The results show that sub-lethal antibiotic concentrations diversely modulate expression of RNAIII, hla and spa. Consistently...

  9. Development of a Scintillation Proximity Assay (SPA) Based, High Throughput Screening Feasible Method for the Identification of PDE12 Activity Modulators.

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    Mang, Samuel; Bucher, Hannes; Nickolaus, Peter

    2016-01-01

    The scintillation proximity assay (SPA) technology has been widely used to establish high throughput screens (HTS) for a range of targets in the pharmaceutical industry. PDE12 (aka. 2'- phosphodiesterase) has been published to participate in the degradation of oligoadenylates that are involved in the establishment of an antiviral state via the activation of ribonuclease L (RNAse-L). Degradation of oligoadenylates by PDE12 terminates these antiviral activities, leading to decreased resistance of cells for a variety of viral pathogens. Therefore inhibitors of PDE12 are discussed as antiviral therapy. Here we describe the use of the yttrium silicate SPA bead technology to assess inhibitory activity of compounds against PDE12 in a homogeneous, robust HTS feasible assay using tritiated adenosine-P-adenylate ([3H]ApA) as substrate. We found that the used [3H]ApA educt, was not able to bind to SPA beads, whereas the product [3H]AMP, as known before, was able to bind to SPA beads. This enables the measurement of PDE12 activity on [3H]ApA as a substrate using a wallac microbeta counter. This method describes a robust and high throughput capable format in terms of specificity, commonly used compound solvents, ease of detection and assay matrices. The method could facilitate the search for PDE12 inhibitors as antiviral compounds.

  10. Influence balneotherapy on spa Truskavets’ with taking Canephron® N on urina lithogenicity and its metabolic and neuroendocrine-immune accompaniments in patients with chronic pyelonephrite and cholecystite

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    Oleksandr V. Shulyak

    2015-11-01

    i.popovych@biph.kiev.ua   SUMMARY Objective. We know that balneotherapy on spa Truskavets' did not significantly affect the parameters of urina Lithogenicity, including Ca/Mg ratio, so search for means of reducing urina Lithogenicity remains relevant. We also know that Phytopreparation Canephron® N recommended for inclusion in complex therapy of chronic pyelonephrite as effective elimination of infectious kidney inflammation, prevention of recurrence of inflammation and lithogenese. Aim: to find out the possibility of reducing urina Lithogenicity influenced balneotherapy on spa Truskavets' by additional taking Canephron® N. Results. Standardized balneotherapy not significantly affect urina Lithogenicity in patients with chronic pyelonephrite and cholecystite, even showed a trend to increase, while additional use Canephron® N significantly reduces urina Lithogenicity by reducing the concentration of Uric acid and downward trend Calcium. Reducing urina Lithogenicity accompanied by a decrease urina concentration Chloride and Potassium, and Baevskiy’s Activity Regulatory Systems Index, Asymmetry δ-, θ- and α-rhythms of background EEG and α-rhythm normalized Power Spectrum Density (PSD in right loci Fp2, F8, T6 and O2, while HRV markers of vagal tone (RMSSD, pNN50, TI also Frequency Deviation θ- and β-rhythms, Amplitude β- and δ-rhythms, δ-rhythm PSD in loci Fp2, F8, T3, T5, O1, O2, β-rhythm PSD in loci Fp1, F4 and θ-rhythm PSD in loci T3 and F7 rising. However, Canephron® N preventes or reverses increasing Uric acid plasma level, Mineralocorticoide Activity, Sympathetic tone, Baevskiy’s Stress Index and PSD ULF HRV also decreasing PSD VLF HRV. Concerning parameters of Immunity Canephron® N decreases blood level active T-Lymphocytes but increases level B-Lymphocytes, Stubnucleary Neutrophiles and total Leukocytes also prevents or reverses increasing CD16+ NK-Lymphocytes, CD8+ and Theophilinesensitive T-Lymphocytes, Monocytes and serum IgM also

  11. [Efficiency of medical and economic activities of a sanatorium-and-spa facility in the active phase of the public health system reform under macroeconomic instability].

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    Poliakov, B A; Kizeev, M V

    2010-01-01

    Results of a comprehensive study have demonstrated that the reform of the public health system currently underway in this country provides conditions for the extension of medical care based at sanatorium-and-spa facilities with simultaneous rise in relevant expenses. Bearing in mind the unstable macroeconomic situation, this requires thorough monitoring medical and economic activities of health resorts for the purpose of enhancing cost efficiency. The goal of optimization can be achieved by increasing competitive capacity based on strict control of expenditures and income redistribution for financing the most promising projects.

  12. Radioactivity of spa waters in Serbia

    International Nuclear Information System (INIS)

    Tanaskovic, I.; Eremic Savkovic, M.; Javorina, Lj.

    2011-01-01

    In this paper, the measurement results of: total alpha and beta activity, as well as specific activity of 226 Ra, 228 Ra, 40 K and conductivity of spa waters of Serbia, are presented. Spa water samples were taken in the fields of different types of geological environment. The maximum values of specific activity of 226 Ra, 228 Ra and 40 K were 0.53 Bq / l, [sr

  13. Health tourism in a Czech health spa.

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    Speier, Amy R

    2011-04-01

    This paper is about the changing shape of health tourism in a Czech spa town. The research focuses on balneotherapy as a traditional Czech healing technique, which involves complex drinking and bathing therapies, as it is increasingly being incorporated into the development of a Czech health tourism industry. Today, the health tourism industry in Mariánske Lázne is attempting to 'harmoniously' combine three elements--balneology, travel and business activities. One detects subtle shifts and consequent incongruities as doctors struggle for control over the medical portion of spa hotels. At the same time, marketing groups are creating new packages for a general clientele, and the implementation of these new packages de-medicalizes balneotherapy. Related to the issue of the doctor's authority in the spa, the changes occurring with the privatization of tourism entails the entrance of 'tourists' to Mariánske Lázne who are not necessarily seeking spa treatment but who are still staying at spa hotels. There is a general consensus among spa doctors and employees that balneotherapy has become commodified. Thus, while balneotherapy remains a traditional form of therapy, the commercial context in which it exists has created a new form of health tourism.

  14. Spa therapy in dermatology

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    Najeeba Riyaz

    2011-01-01

    Full Text Available Spa therapy constitutes the use of mineral springs and thermal mud to soothe and heal various ailments. Like the mineral springs, seas and oceans are also important centers for spa therapy of which the most important is Dead Sea (DS. DS has been famous for thousands of years for its miraculous curative and cosmetic properties. Intensive research is going on using DS minerals in a wide range of dermatological conditions especially psoriasis, atopic dermatitis, vitiligo and other eczemas and several papers have been published in various international and pharmacological journals.

  15. Strand SPA & Konverentsikeskus

    Index Scriptorium Estoniae

    2008-01-01

    Strand SPA & Konverentsikeskus on Pärnu suurim äri- ja konverentsiklientidele suunatud hotell, mis klientide seas on hinnatud just selle kompleksuse tõttu, kuna kõik, mida külaline vajab ja soovib, on olemas ühe katuse all

  16. Effect of spa therapy with saline balneotherapy on oxidant/antioxidant status in patients with rheumatoid arthritis: a single-blind randomized controlled trial

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    Karagülle, Mine; Kardeş, Sinan; Karagülle, Oğuz; Dişçi, Rian; Avcı, Aslıhan; Durak, İlker; Karagülle, Müfit Zeki

    2017-01-01

    Oxidative stress has been shown to play a contributory role in the pathogenesis of rheumatoid arthritis (RA). Recent studies have provided evidence for antioxidant properties of spa therapy. The purpose of this study is to investigate whether spa therapy with saline balneotherapy has any influence on the oxidant/antioxidant status in patients with RA and to assess clinical effects of spa therapy. In this investigator-blind randomized controlled trial, we randomly assigned 50 patients in a 1:1 ratio to spa therapy plus standard drug treatment (spa group) or standard drug treatment alone (control group). Spa group followed a 2-week course of spa therapy regimen consisting of a total of 12 balneotherapy sessions in a thermal mineral water pool at 36-37 °C for 20 min every day except Sunday. All clinical and biochemical parameters were assessed at baseline and after spa therapy (2 weeks). The clinical parameters were pain intensity, patient global assessment, physician global assessment, Health Assessment Questionnaire disability index (HAQ-DI), Disease Activity Score for 28-joints based on erythrocyte sedimentation rate (DAS28-4[ESR]). Oxidative status parameters were malondialdehyde (MDA), nonenzymatic superoxide radical scavenger activity (NSSA), antioxidant potential (AOP), and superoxide dismutase (SOD). The NSSA levels were increased significantly in the spa group ( p = 0.003) but not in the control group ( p = 0.509); and there was a trend in favor of spa therapy for improvements in NSSA levels compared to control ( p = 0.091). Significant clinical improvement was found in the spa group compared to the control in terms of patient global assessment ( p = 0.011), physician global assessment ( p = 0.043), function (HAQ-DI) ( p = 0.037), disease activity (DAS28-4[ESR]) (0.044) and swollen joint count (0.009), and a trend toward improvement in pain scores (0.057). Spa therapy with saline balneotherapy exerts antioxidant effect in patients with RA as reflected by the

  17. Spa Products as Main Orientation in Wellness Tourism in Bali

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    I Gusti Made Wendri

    2018-03-01

    Full Text Available Wellness Spa is developed from conventional spa in response to the influence of the present tourism trend which is much in demand of the achievement of wellness aspect of life. Wellness tourism is a subdivision of health tourism. Wellness spa is the core product for wellness tourism. In fact, to date, people’s knowledge about wellness spa is still poor. This fact has motivated the implementation of this research under the title “Spa Products as Main Orientation in Wellness Tourism in Bali”. The objective of the research is to find out what products becomes the orientation in wellness tourism in Ubud as well as in South Badung. This qualitative research uses a phenomenological approach to the study. The determination of the informants is purposively done, and the information concerning the object of the research is obtained by deep interview controlled by a checklist based on Wellness Wheel concept. The location of the research is Ubud and South Badung areas, the latter represented by Nusa Dua, Jimbaran, and Kuta. The research uses 10 informants, 5 from Ubud and 5 from South Badung. The informants include spa managers and spa therapists. The result of the research shows that such packages as Bali spa ritual package, personal growth, and eco-adventure package become the most attractive products offered by wellness tourism industry and enjoyed by the tourists for the fulfilment of the tourists' wellness needs.

  18. Translational Science: How experimental research has contributed to the understanding of spontaneous Physical Activity and Energy Homeostasis

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    Izabelle D Benfato

    2017-05-01

    Full Text Available Abstract Spontaneous physical activity (SPA consists of all daily living activities other than volitional exercise (e.g. sports and fitness-related activities. SPA is an important component of energy expenditure and may protect from overweight and obesity. Little is known about the biological regulation of SPA, but animal researchhas contributedsignificantly to expand our knowledge in this field. Studies in rodents have shown that SPA is influenced by nutrients and volitional exercise. High-fat diet seems to decrease SPA, which contributes to weigh gain. Volitional exercisemayalso reduce SPA, helping to explain the commonly reported low efficiency of exercise to cause weight loss, and highlighting the need to finda volume/intensity of exercise to maximize total daily energy expenditure. Animal studieshave also allowed for the identification of some brain areas and chemical mediatorsinvolved in SPA regulation. These discoveries could enable the development of new therapeutics aiming to enhance SPA.

  19. Radioactivity measurements and risk assessments of spa waters in some areas in Turkey.

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    Duran, Selcen Uzun; Kucukomeroglu, Belgin; Damla, Nevzat; Taskin, Halim; Celik, Necati; Cevik, Uğur; Ersoy, Hakan

    2017-03-01

    The current study presents the results of the activity of radionuclides in spa waters, and evaluates their radiological influences on the population consuming these waters in the Central and Eastern Black Sea regions of Turkey. Since these waters are used for therapy and consumption purposes unconsciously, their radiological impact on the people was computed by taking into consideration the annual intake through ingestion of 226 Ra, 232 Th, 40 K, 137 Cs and 222 Rn. The mean activities were estimated to be 11.35 for gross alpha, 6.23 for gross beta, 2.96 for 226 Ra, 0.42 for 232 Th, 0.069 for 137 Cs, 0.19 for 40 K, and 267 Bq L -1 for 222 Rn, respectively. The estimated effective doses from spa water were found to be 49.77 µSv a -1 ( 226 Ra), 5.95 µSv a -1 ( 232 Th), 0.07 µSv a -1 ( 137 Cs), 0.83 µSv a -1 ( 40 K) and 56.03 µSv a -1 ( 222 Rn). These values were evaluated and compared with related verified values from literature. Also, physico-chemical characterizations of spa water samples considered in the current study were investigated. This study would be useful for consumers and official authorities for the assessment of radiation exposure risk due to usage of the considered spa waters.

  20. Formation of trihalomethanes as disinfection byproducts in herbal spa pools.

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    Fakour, Hoda; Lo, Shang-Lien

    2018-04-09

    Herbal spa treatments are favorite recreational activities throughout the world. The water in spas is often disinfected to control pathogenic microorganisms and guarantee hygiene. However, chlorinated water may cause the formation of disinfection byproducts (DBPs). Although there have been many studies on DBP formation in swimming pools, the role of organic matter derived from herbal medicines applied in herbal spa water has been largely neglected. Accordingly, the present study investigated the effect of herbal medicines on the formation of trihalomethanes (THMs) in simulated herbal spa water. Water samples were collected from a spa pool, and then, disinfection and herbal addition experiments were performed in a laboratory. The results showed that the organic molecules introduced by the herbal medicines are significant precursors to the formation of THMs in spa pool water. Since at least 50% of THMs were produced within the first six hours of the reaction time, the presence of herbal medicines in spa water could present a parallel route for THM exposure. Therefore, despite the undeniable benefits of herbal spas, the effect of applied herbs on DBP formation in chlorinated water should be considered to improve the water quality and health benefits of spa facilities.

  1. PERFORMANCE ANALYSIS ON SPA SERVICE AT BADUNG DAN GIANYAR REGENCIES

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    Dewa Ayu i Laksmiadi Janapriat

    2016-03-01

    Full Text Available Over the last ten years, spa as one of the products of wellness tourism is growing very fast in Bali, necessitating the development strategy in accordance with the conditions of Bali. The rapid development momentum for the business of spa is opened in Bali, although in the external side of the business will compete with the international trade environment to take advantage and create sustainable economic growth prospects. This will be an opportunity for Bali as a destination spa in the future. In an effort to maintain and continue to develop quality as the best spa destinations in the world, we need the right strategy to make the creation and supporting product innovation spa in Bali. This study aims to create an integrated assessment of the extent of the influence of the utilization of natural resources, human resources and local knowledge of the existence and essence of spa in Bali and methods for utilizing natural resources, human resources and local knowledge of Bali on development of spa in Bali. Research design and methods of approach to the problem that are done in this study using descriptive design, where the planning and execution of research conducted in the form of field data are collected in the form of surveys, questionnaires and statistical data processing. The target population in this study is divided into three, namely: the company or a place that offers spa services, spa services supporting manufacturers and both foreign and domestic tourists who use the services of spa services in Badung and Gianyar, by assuming the two districts can represent the tourist population to Bali. Based on several case studies found that the performance of spa services in terms of utilization of natural resources, human resources, and local wisdom of Bali, particularly in terms of (1 the atmosphere (ambience, (2 equipment and design, (3 the qualifications and skills of the therapist, (4 treatment menu, and (5 the quality of services as a whole has

  2. Positive and cost-effectiveness effect of spa therapy on the resumption of occupational and non-occupational activities in women in breast cancer remission: a French multicentre randomised controlled trial.

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    Mourgues, Charline; Gerbaud, Laurent; Leger, Stéphanie; Auclair, Candy; Peyrol, Fleur; Blanquet, Marie; Kwiatkowski, Fabrice; Leger-Enreille, Anne; Bignon, Yves-Jean

    2014-10-01

    The main aim was to assess the effects of a spa treatment on the resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission. A cost-effectiveness analysis (CEA) was also performed. A multicentre randomised controlled trial was carried out between 2008 and 2010 in the University Hospital of Auvergne and two private hospitals in Clermont-Ferrand, France. Eligible patients were women in complete breast cancer remission without contraindication for physical activities or cognitive disorders and a body mass index between 18.5 and 40 kg/m(2). The intervention group underwent spa treatment combined with consultation with dietician whereas the control underwent consultations with the dietician only. Of the 181 patients randomised, 92 and 89 were included in the intervention and the control groups, respectively. The CEA involved 90 patients, 42 from the intervention group and 48 from the control group. The main results showed a higher rate of resumption of occupational activities in the intervention group (p = 0.0025) and a positive effect of the intervention on the women's ability to perform occupational activities 12 months after the beginning of the study (p = 0.0014), and on their ability to perform family activities (p = 0.033). The stay in a thermal centre was cost-effective at 12 months. Spa treatment is a cost-effective strategy to improve resumption of occupational and non-occupational activities and the abilities of women in breast cancer remission. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Spa-goers’ Characteristics, Motivations, Preferences and Perceptions: Evidence from Elounda, Crete

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    Nikolaos Trihas

    2016-12-01

    Full Text Available Spa and wellness tourism is one of the fastest-growing market segments in the hospitality and tourism industry. The aim of this study is to investigate and identify spa-goers’ characteristics, motivations, preferences and perceptions, providing a better understanding of the main features of this type of tourists’ behavior and expectations from a spa and wellness centre. Primary quantitative research was conducted via a structured questionnaire in a sample of 123 spa customers at Elounda in Crete. The results of the study revealed a number of important factors that influence them when choosing a spa, namely the cleanliness and the maintenance of a spa, the staff knowledge and hygiene, the personnel behavior and courtesy, and the quality of services. In addition, the main reason for visiting the spa is for stress relief/relaxation, followed by physical health improvement and beauty treatments. Findings and discussion of this study are useful to industry practitioners (spa and wellness service providers who wish to develop appropriate marketing strategies and enhance customer satisfaction and academic researchers interested in spa and wellness tourism.

  4. Sensitivity Test of Parameters Influencing Flood Hydrograph Routing with a Diffusion-Wave Distributed using Distributed Hydrological Model, Wet Spa, in Ziarat Watershed

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    narges javidan

    2017-02-01

    Full Text Available Introduction: Flood routing is a procedure to calculate flood stage and water depth along a river or to estimate flood hydrograph at river downstream or at reservoir outlets using the upstream hydrography . In river basins, excess rainfall is routed to the basin outlet using flow routing techniques to generate flow hydrograph. A GIS-based distributed hydrological model, Wet Spa, has been under development suitable for flood prediction and watershed management on a catchment scale. The model predicts outflow hydrographs at the basin outlet or at any converging point in the watershed, and it does so in a user-specified time step. The model is physically based, spatially distributed and time-continuous, and simulates hydrological processes of precipitation, snowmelt, interception, depression, surface runoff, infiltration, evapotranspiration, percolation, interflow, groundwater flow, etc. continuously both in time and space, for which the water and energy balance are maintained on each raster cell. Surface runoff is produced using a modified coefficient method based on the cellular characteristics of slope, land use, and soil type, and allowed to vary with soil moisture, rainfall intensity and storm duration. Interflow is computed based on the Darcy’s law and the kinematic approximation as a function of the effective hydraulic conductivity and the hydraulic gradient, while groundwater flow is estimated with a linear reservoir method on a small subcatchment scale as a function of groundwater storage and a recession coefficient. Special emphasis is given to the overland flow and channel flow routing using the method of linear diffusive wave approximation, which is capable to predict flow discharge at any converging point downstream by a unit response function. The model accounts for spatially distributed hydrological and geophysical characteristics of the catchment. Determination of the river flow hydrograph is a main target in hydrology

  5. Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919

    Science.gov (United States)

    Aleksandrzak-Piekarczyk, Tamara; Koryszewska-Bagińska, Anna; Grynberg, Marcin; Nowak, Adriana; Cukrowska, Bożena; Kozakova, Hana; Bardowski, Jacek

    2016-01-01

    Here, we report the extensive bioinformatic and functional analyses of the unusual pLOCK 0919, a plasmid originating from the probiotic Lactobacillus casei LOCK 0919 strain. This plasmid is atypical because it harbors the spaCBA-srtC gene cluster encoding SpaCBA pili. We show that all other spaCBA-srtC sequences of the Lactobacillus genus that have been previously described and deposited in GenBank are present in the chromosomal DNA. Another important observation for pLOCK 0919 is that the spaCBA-srtC gene cluster and its surrounding genes are highly similar to the respective DNA region that is present in the most well-known and active SpaCBA pili producer, the probiotic Lactobacillus rhamnosus GG strain. Our results demonstrate that the spaCBA-srtC clusters of pLOCK 0919 and L. rhamnosus GG are genealogically similar, located in DNA regions that are rich in transposase genes and are poorly conserved among the publicly available sequences of Lactobacillus sp. In contrast to chromosomally localized pilus gene clusters from L. casei and Lactobacillus paracasei, the plasmidic spaC of L. casei LOCK 0919 is expressed and undergoes a slight glucose-induced repression. Moreover, results of series of in vitro tests demonstrate that L. casei LOCK 0919 has an adhesion potential, which is largely determined by the presence of the pLOCK 0919 plasmid. In particular, the plasmid occurrence positively influenced the hydrophobicity and aggregation abilities of L. casei LOCK 0919. Moreover, in vivo studies indicate that among the three Lactobacillus strains used to colonize the gastrointestinal tract of germ-free mice, already after 2 days of colonization, L. casei LOCK 0919 became the dominant strain and persisted there for at least 48 days. PMID:26637469

  6. Aplicació Microsoft .Net : Hotel Spa

    OpenAIRE

    Marquès Palmer, Jordi

    2010-01-01

    Desenvolupament d'una aplicació amb Microsoft .NET, WCF, WPF, Linq2SQL, d'un Hotel Spa. Desarrollo de una aplicación con Microsoft .NET, WCF, WPF, Linq2SQL, de un Hotel Spa. Application development using Microsoft .NET, WCF, WPF, Linq2SQL, for a Spa Hotel.

  7. SWOT ANALYSIS OF SPA TOURISM IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Aleksandar Davchev

    2016-06-01

    Full Text Available Our time is marked by the increasingly dynamic changing environment. The new conditions in which we operate are characterized by increasing complexity and labor activities that require more responsible behavior. The rising levels of stress and the increasing lack of free time for relaxation and recreation require a new look at the possibilities for the prevention of personal health. The plane of the consumer society in which we live is increasingly shifted by aspiration and vision of an environmentally friendly lifestyle. The focus here is the implementation of a multilevel wellness concept that changes qualitatively the status quo and seeks for ways to harmonize the body with the nature. One of the options is the practice of SPA tourism in whose genesis is the multilayered beneficial impact of a series of procedures and actions. This new alternative through its economic dimensions is an attractive business niche which over time becomes an industry. The current state of the SPA tourism in Bulgaria is controversial despite existing achievements and introduced best practices. Traditions in this direction and the presence of favorable basis for its approval, however, are not sufficient to achieve stability and an upward trend in development. There are existing a number of weaknesses and negative aspects that create frustration in users, which is a real threat to its future. The proposed SWOT-analysis as part of a comprehensive and multilateral study of the state of SPA tourism in Bulgaria reveals some of the existing problems. There have been some suggestions to minimize the impact of weaknesses and eliminate the errors found in leading business organizations managing processes. A detailed analysis and evaluation of the formulated conclusions is ahead, as well as concluding on ideas to improve the state of the sector – a subject of a further investigation by the author.

  8. Quantitative Expression Analysis of SpA, FnbA and Rsp Genes in Staphylococcus aureus: Actively Associated in the Formation of Biofilms.

    Science.gov (United States)

    Yeswanth, Sthanikam; Chaudhury, Abhijit; Sarma, Potukuchi Venkata Gurunadha Krishna

    2017-12-01

    In Staphylococcus aureus, adherence and secretory proteins play chief role in the formation of biofilms. This mode of growth exhibits resistance to a variety of antibiotics and spreads its infections. In the present study, secretary and adherence proteins, Protein-A, Fibronectin-binding protein-A (FnbA) and Rsp (a transcription regulator encoding proteolytic property) expression levels were evaluated at different stages of growth in S. aureus ATCC12600 a drug-sensitive strain and multidrug-resistant strains of S. aureus. Initially, the SpA, FnbA and Rsp genes of S. aureus ATCC12600 were cloned, sequenced, expressed and characterized. The proteolytic property of recombinant Rsp was conspicuously shown when this pathogen was grown in aerobic conditions correlating with reduced biofilm units. In anaerobic mode of growth, S. aureus exhibited a higher expression of SpA and FnbA in early and mid adherence phases and finally stabilized at 48 h of incubation. This expression was more pronounced in methicillin-resistant strains (LMV1-8 and D1-4) of S. aureus. In all these stages, Rsp gene expression was at the lowest level and these results concur with the increased biofilm units. The results of the present study explain proteins chiefly contribute in the formation of biofilms.

  9. Spa therapy adjunct to pharmacotherapy is beneficial in rheumatoid arthritis: a crossover randomized controlled trial

    Science.gov (United States)

    Karagülle, Mine; Kardeş, Sinan; Dişçi, Rian; Karagülle, Müfit Zeki

    2018-02-01

    This study aims to investigate whether 2-week spa therapy, as an adjunct to usual pharmacological therapy, has any beneficial effect in patients with rheumatoid arthritis (RA). In this single-blind crossover study, 50 patients were randomly assigned in a 1:1 manner to receive usual pharmacological therapy plus 2-week spa therapy or usual pharmacological therapy alone (period 1.6 months); after a 9-month washout, patients were crossed over to the opposite assignment (period 2.6 months). Spa therapy program included a daily saline balneotherapy session at 36-37 °C for 20 min except Sundays. The clinical outcomes were evaluated at baseline, after spa therapy (2 weeks) and 3 and 6 months after the spa therapy in both period and were pain (Visual Analogue Scale (VAS)), patient and physician global assessments (VAS), Health Assessment Questionnaire (HAQ), and Disease Activity Score (DAS28). Spa therapy was superior to control therapy in improving all the assessed clinical outcomes at the end of the spa therapy. This superiority persisted significantly in physician global assessment ( p = 0.010) and with a trend in favor of spa group in patient global assessment ( p = 0.058), function ( p = 0.092), and disease activity ( p = 0.098) at 3 months. Statistically significant improvements were found in spa therapy compared to control in disease activity ( p = 0.006) and patient ( p = 0.020) and physician global ( p = 0.011) assessments, and a trend toward improvements in pain ( p = 0.069) and swollen joints ( p = 0.070) at 6 months. A 2-week spa therapy adjunct to usual pharmacological therapy provided beneficial clinical effects compared to usual pharmacological therapy alone, in RA patients treated with traditional disease-modifying antirheumatic drugs. These beneficial effects may last for 6 months.

  10. Harnn Natural Home Spa Business Plan

    OpenAIRE

    Kusol, Chompunuch

    2008-01-01

    Home Spa Partnership is looking for the amount of 50,000 GBP from an investor to invest in the business. The Company offers 20% of its authorised share capital for 17,500 GBP and the preference shares amounting to 32,500 GBP. This amount will be brought into the infrastructures and initial overhead cost for the start-up Thai spa business in the UK under 'Harnn Natural Home Spa' brand. The Company Home Spa Partnership was incorporated in July 2008 with issued share capital of 80,000...

  11. [Nonnius and the Spa cure].

    Science.gov (United States)

    Lecomte, J; Lemli, J; Marganne, M H; Melard, M

    1996-01-01

    The 12th of July 1635, Jan van Beverwyck wrote a letter from Dordrecht to his esteemed friend Luis Nunez, in Antwerp. He asked him for indications about the cure of kidney stones of which he was suffering. He had just passed two calculi very painfully. Nunez answered on July 31. His letter summarized his own experience with this disease. In such cases, temperate diuretics and emollients are well indicated: ingestion of light decoctions of Malva and Viola, Caerefolium and Parieteria as well as Marshmallow syrup. No purge and no 'chemicals'. However, the best remedy was drinking Spa water. Usually the best way to absorb it is to come to the springs, in the Ardennes, part of the independent Principality of Liège. However, considering the horrors of the war (the Thirty Years War) endangering the country, van Beverwyck would be wise to drink imported water during 40 or 50 days, while staying home quietly, in Dordrecht. The letter points out the importance of provoked diuresis in the treatment of kidney stones. On the other hand the letter is an illustration of the continuing contacts between the United Provinces and the Spanish territories and of the commercial traffic between Antwerp, Dordrecht and Spa. The exported water was bottled from many 'pouhons'. It was acid, ferruginous, sulfurous and saturated with carbon dioxide; no pathogen germs, at least at the spring. Nunez quoted the large number of his patients cured with Spa water in Antwerp. This is an illustration of its commercial expansion even during this critical period.

  12. From sulphur to perfume: spa and SPA at Monchique, Algarve.

    Science.gov (United States)

    Bastos, Cristiana

    2011-04-01

    In the thermal village of Monchique, Algarve, different streams of water-related knowledge and practices coexisted for centuries. Those waters were traditionally known as aguas santas (holy waters) and believed to have redemptive healing powers. In the seventeenth century, the Catholic church took control of the place, refashioned the bathing rituals, developed infrastructures and provided assistance to the patients, granting free treatment to the poor. In the nineteenth century, the state replaced the church and imposed that treatments should be provided by professionals trained in the scientific principles of medical hydrology. Secular and scientific as they were, clinical logbooks still allowed for the account of patients that embodied miracle-like redemptive cures 'at the third bath'. People went to Monchique both for its magic and its medicine, bringing in the body ailments achieved in their lives of hard labour. They also went there for a socialising break while healing. From mendicants to rich landowners, coming mostly from the Algarve and neighbouring Alentejo, they crowded the place in summertime. In the twentieth century, as in other places in continental Europe, the spa evolved into a highly medicalised place that qualified for medical expenses reimbursements, which implied the eclipsing--at least from representation--of its leisure component. In the twenty-first century, a new trend of consumer-centred, market-based, post-water balneology with an emphasis on wellness and leisure reinvented the spa as place for lush and diversified consumption. This article argues that the seemingly contradictory systems (markets and medicine) coexist much in the same way that magic, religion and medicine coexisted in the old water sites. The new SPAs, rather than putting an end to the old spas, have enabled them to survive by reinventing thermal sites as places of attraction and leisure.

  13. Radon and progeny sourced dose assessment of spa employees in balneological sites

    International Nuclear Information System (INIS)

    Kemal Uzun, Sefa; Demiroez, Isik

    2016-01-01

    This study was conducted in the scope of IAEA project with the name 'Establishing a Systematic Radioactivity Survey and Total Effective Dose Assessment in Natural Balneological Sites' (TUR/9/018), at the Health Physics department of Saraykoey Nuclear Research and Training Center (SANAEM). The aim of this study is estimation of radon and progeny sourced effective dose for the people who are working at the spa facilities by measuring radon activity concentration (RAC) at the ambient air of indoor spa pools and dressing rooms. As it is known, the source of the radon gas is the radium content of the earth crust. Therefore, thermal waters coming from ground may contain dissolved radon and the radon can diffuse water to air. So the ambient air of spa pools can contain serious RAC that depends on a lot of parameters. In this regard, RAC measurements were executed at the 70 spa facilities in Turkey. The measurements were done with both active and passive methods at ambient air of spa pools and dressing rooms. Thus, active measurements were carried out by using the Alphaguard R with diffusion mode during half an hour, and passive measurements were carried out by using the humidity resistive CR-39 radon detectors during 2 months. Results show that RAC values at ambient air of spa pools varies between 13 Bq m -3 and 10 kBq m -3 . Because long-term measurements are more reliable, if it is available, for dose calculations passive radon measurements (with CR-39 detectors) at ambient air of spa pools and dressing rooms were used, otherwise active measurement results were used. With the measurement by the conversion coefficients of ICRP 65 and occupational data of the employees has got from questionnaire forms, effective dose values were calculated. According to the calculations, spa employees are exposed to annual average dose between 0.05 and 29 mSv because of radon and progeny. (authors)

  14. Description of the behavior of an aquifer by using continuous radon monitoring in a thermal spa

    International Nuclear Information System (INIS)

    Sainz, Carlos; Rábago, Daniel; Fuente, Ismael; Celaya, Santiago; Quindós, Luis Santiago

    2016-01-01

    Radon ( 222 Rn) levels in air and water have been analyzed continuously for almost a year in Las Caldas de Besaya thermal spa, north Spain. Radon is a naturally occurring noble gas from the decay of radium ( 226 Ra) both constituents of radioactive uranium 238 series. It has been recognized as a lung carcinogen by the World Health Organization (WHO) and International Agency for Research on Cancer (IARC). Furthermore the Royal Decree R.D 1439/2010 of November, 2010 establishes the obligation to study occupational activities where workers and, where appropriate, members of the public are exposed to inhalation of radon in workplaces such as spas. Together with radon measures several physico-chemical parameters were obtained such as pH, redox potential, electrical conductivity and air and water temperature. The devices used for the study of the temporal evolution of radon concentration have been the RTM 2100, the Radon Scout and gamma spectrometry was complementarily used to determine the transfer factor of the silicone tubes in the experimental device. Radon concentrations obtained in water and air of the spa are high, with an average of 660 Bq/l and 2900 Bq/m 3 respectively, where water is the main source of radon in the air. Radiation dose for workers and public was estimated from these levels of radon. The data showed that the thermal processes can control the behavior of radon which can be also influenced by various physical and chemical parameters such as pH and redox potential. - Highlights: • Radon in water is the major source of indoor air radon concentration in thermal facilities. • Radon in water has been used to characterize the origin of water used for treatments in a spa. • Preliminary dose assessment from radon exposure has been performed.

  15. Description of the behavior of an aquifer by using continuous radon monitoring in a thermal spa

    Energy Technology Data Exchange (ETDEWEB)

    Sainz, Carlos, E-mail: sainzc@unican.es; Rábago, Daniel; Fuente, Ismael; Celaya, Santiago; Quindós, Luis Santiago

    2016-02-01

    Radon ({sup 222}Rn) levels in air and water have been analyzed continuously for almost a year in Las Caldas de Besaya thermal spa, north Spain. Radon is a naturally occurring noble gas from the decay of radium ({sup 226}Ra) both constituents of radioactive uranium 238 series. It has been recognized as a lung carcinogen by the World Health Organization (WHO) and International Agency for Research on Cancer (IARC). Furthermore the Royal Decree R.D 1439/2010 of November, 2010 establishes the obligation to study occupational activities where workers and, where appropriate, members of the public are exposed to inhalation of radon in workplaces such as spas. Together with radon measures several physico-chemical parameters were obtained such as pH, redox potential, electrical conductivity and air and water temperature. The devices used for the study of the temporal evolution of radon concentration have been the RTM 2100, the Radon Scout and gamma spectrometry was complementarily used to determine the transfer factor of the silicone tubes in the experimental device. Radon concentrations obtained in water and air of the spa are high, with an average of 660 Bq/l and 2900 Bq/m{sup 3} respectively, where water is the main source of radon in the air. Radiation dose for workers and public was estimated from these levels of radon. The data showed that the thermal processes can control the behavior of radon which can be also influenced by various physical and chemical parameters such as pH and redox potential. - Highlights: • Radon in water is the major source of indoor air radon concentration in thermal facilities. • Radon in water has been used to characterize the origin of water used for treatments in a spa. • Preliminary dose assessment from radon exposure has been performed.

  16. SP-A binding sites on bovine alveolar macrophages.

    Science.gov (United States)

    Plaga, S; Plattner, H; Schlepper-Schaefer, J

    1998-11-25

    Surfactant protein A (SP-A) binding to bovine alveolar macrophages was examined in order to characterize SP-A binding proteins on the cell surface and to isolate putative receptors from these cells that could be obtained in large amounts. Human SP-A, unlabeled or labeled with gold particles, was bound to freshly isolated macrophages and analyzed with ELISA or the transmission electron microscope. Binding of SP-A was inhibited by Ca2+ chelation, by an excess of unlabeled SP-A, or by the presence of 20 mg/ml mannan. We conclude that bovine alveolar macrophages expose binding sites for SP-A that are specific and that depend on Ca2+ and on mannose residues. For isolation of SP-A receptors with homologous SP-A as ligand we isolated SP-A from bovine lung lavage. SDS-PAGE analysis of the purified SP-A showed a protein of 32-36 kDa. Functional integrity of the protein was demonstrated. Bovine SP-A bound to Dynabeads was used to isolate SP-A binding proteins. From the fractionated and blotted proteins of the receptor preparation two proteins bound SP-A in a Ca2+-dependent manner, a 40-kDa protein showing mannose dependency and a 210-kDa protein, showing no mannose sensitivity. Copyright 1998 Academic Press.

  17. Radon in the spa of Bizovac

    International Nuclear Information System (INIS)

    Planinic, J.; Faj, Z.; Suveljak, B.; Radolic, V.

    1996-01-01

    The radon concentration in the air and water of the Bizovac spa was measured by the Radhome silicon detector and the average values were obtained as 70 Bq/m 3 in the indoor pool, 40 Bq/m 3 in the hotel room, 135 Bq/m 3 in the closed therapeutic bathroom, but the geothermal water had a Rn concentration of 25.3 kBq/m 3 and the potable one 2.7 kBq/m 3 . The Rn transfer factor (f) from water to air in the indoor pool and therapeutic bathroom was 10 and 40 times higher than for normal dwellings (f n =10 -4 ), respectively. The effective equivalent dose of inhaled radon for permanent personnel under the worst conditions in the spa was 5.4 mSv/y, but visitors spending two weeks in the spa could receive the dose of 77 μSv. (author). 6 refs., 1 fig

  18. The SPA Tourism Perception in Romania

    Directory of Open Access Journals (Sweden)

    Ionica SOARE

    2014-11-01

    Full Text Available Tourism or geriatric-medical and wellness tourism are market segments that lately have registered significant increases. The need to define, organize, and promote these sectors. This item is intended to synthesize developments and challenges market growth wellness and medical tourism. For the industry spa these developments may represent an opportunity to take full advantage of wellness and medical tourism.

  19. Radon measurement in the spa of Bizovac

    International Nuclear Information System (INIS)

    Faj, Z.; Radolic, V.; Suveljak, B.; Planinic, J.

    1996-01-01

    The spa of Bizovac is located 20 km on the west of Osijek in east Croatia. Radon concentrations in the air and water of the Bizovac spa were measured by the Radhome silicon detector and the average values were obtained as 70 Bq/m 3 in the indoor pool, 40 Bq/m 3 in the hotel room and 135 Bq/m 3 in the closed therapeutic bathroom. A special experiment was performed in a closed therapeutic bathroom by three bathtubes filled up with geothermal water as well as normal (potable) one from water-supply. Using measured radon concentrations in air by Radhome detector under the mentioned conditions in the closed bathroom, radon concentrations were assessed for the geothermal water as 25.3 Bq/m 3 and 2.7 Bq/m 3 for potable water. Radon in potable water, measured by the sampling glass ampoule and scintillation cell, had the concentration of 3.5 Bq/m 3 . The radon transfer factor from water to air in the indoor pool and therapeutic bathroom was 10 and 40 times higher than for normal dwelling factor (10 -4 ), respectively. The effective dose equivalent of inhaled radon for permanent personnel under the worst conditions in the spa (closed therapeutic bathroom) was 5.4 mSv/y, but visitors spending two weeks in the Bizovac spa could receive the dose of 77 μSv. (author)

  20. PREREQUISITES FOR DEVELOPMENT OF SPA TOURISM IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Manuela Vucheva

    2016-12-01

    Full Text Available The demand for spa tourism in Bulgaria has increased 3 times in the last five years. Worldwide demand for spa for travel increased 2 times since 2004. Indications show that spa tourism is developing in a positive direction, both in Bulgaria and abroad. In Bulgaria there are 25 spa destinations where there are hydromineral fields and complexes for accommodation and rest. The paper provides key conclusions in relation to the development of spa tourism in Bulgaria and recommendations for improvements in marketing and advertising and combination with other types of tourism.

  1. SPA: a probabilistic algorithm for spliced alignment.

    Directory of Open Access Journals (Sweden)

    2006-04-01

    Full Text Available Recent large-scale cDNA sequencing efforts show that elaborate patterns of splice variation are responsible for much of the proteome diversity in higher eukaryotes. To obtain an accurate account of the repertoire of splice variants, and to gain insight into the mechanisms of alternative splicing, it is essential that cDNAs are very accurately mapped to their respective genomes. Currently available algorithms for cDNA-to-genome alignment do not reach the necessary level of accuracy because they use ad hoc scoring models that cannot correctly trade off the likelihoods of various sequencing errors against the probabilities of different gene structures. Here we develop a Bayesian probabilistic approach to cDNA-to-genome alignment. Gene structures are assigned prior probabilities based on the lengths of their introns and exons, and based on the sequences at their splice boundaries. A likelihood model for sequencing errors takes into account the rates at which misincorporation, as well as insertions and deletions of different lengths, occurs during sequencing. The parameters of both the prior and likelihood model can be automatically estimated from a set of cDNAs, thus enabling our method to adapt itself to different organisms and experimental procedures. We implemented our method in a fast cDNA-to-genome alignment program, SPA, and applied it to the FANTOM3 dataset of over 100,000 full-length mouse cDNAs and a dataset of over 20,000 full-length human cDNAs. Comparison with the results of four other mapping programs shows that SPA produces alignments of significantly higher quality. In particular, the quality of the SPA alignments near splice boundaries and SPA's mapping of the 5' and 3' ends of the cDNAs are highly improved, allowing for more accurate identification of transcript starts and ends, and accurate identification of subtle splice variations. Finally, our splice boundary analysis on the human dataset suggests the existence of a novel non

  2. Supersymmetry Parameter Analysis : SPA Convention and Project

    CERN Document Server

    Aguilar-Saavedra, J A; Allanach, Benjamin C; Arnowitt, R; Baer, H A; Bagger, J A; Balázs, C; Barger, V; Barnett, M; Bartl, Alfred; Battaglia, M; Bechtle, P; Belyaev, A; Berger, E L; Blair, G; Boos, E; Bélanger, G; Carena, M S; Choi, S Y; Deppisch, F; Desch, Klaus; Djouadi, A; Dutta, B; Dutta, S; Díaz, M A; Eberl, H; Ellis, Jonathan Richard; Erler, Jens; Fraas, H; Freitas, A; Fritzsche, T; Godbole, Rohini M; Gounaris, George J; Guasch, J; Gunion, J F; Haba, N; Haber, Howard E; Hagiwara, K; Han, L; Han, T; He, H J; Heinemeyer, S; Hesselbach, S; Hidaka, K; Hinchliffe, Ian; Hirsch, M; Hohenwarter-Sodek, K; Hollik, W; Hou, W S; Hurth, Tobias; Jack, I; Jiang, Y; Jones, D R T; Kalinowski, Jan; Kamon, T; Kane, G; Kang, S K; Kernreiter, T; Kilian, W; Kim, C S; King, S F; Kittel, O; Klasen, M; Kneur, J L; Kovarik, K; Kraml, Sabine; Krämer, M; Lafaye, R; Langacker, P; Logan, H E; Ma, W G; Majerotto, Walter; Martyn, H U; Matchev, K; Miller, D J; Mondragon, M; Moortgat-Pick, G; Moretti, S; Mori, T; Moultaka, G; Muanza, S; Mukhopadhyaya, B; Mühlleitner, M M; Nauenberg, U; Nojiri, M M; Nomura, D; Nowak, H; Okada, N; Olive, Keith A; Oller, W; Peskin, M; Plehn, T; Polesello, G; Porod, Werner; Quevedo, Fernando; Rainwater, D L; Reuter, J; Richardson, P; Rolbiecki, K; de Roeck, A; Weber, Ch.

    2006-01-01

    High-precision analyses of supersymmetry parameters aim at reconstructing the fundamental supersymmetric theory and its breaking mechanism. A well defined theoretical framework is needed when higher-order corrections are included. We propose such a scheme, Supersymmetry Parameter Analysis SPA, based on a consistent set of conventions and input parameters. A repository for computer programs is provided which connect parameters in different schemes and relate the Lagrangian parameters to physical observables at LHC and high energy e+e- linear collider experiments, i.e., masses, mixings, decay widths and production cross sections for supersymmetric particles. In addition, programs for calculating high-precision low energy observables, the density of cold dark matter (CDM) in the universe as well as the cross sections for CDM search experiments are included. The SPA scheme still requires extended efforts on both the theoretical and experimental side before data can be evaluated in the future at the level of the d...

  3. [The topical problems of pediatric balneotherapy and the spa and health resort-based treatment of the children].

    Science.gov (United States)

    Razumov, A N; Khan, M A

    2016-01-01

    This article is devoted to the topical problems of pediatric balneotherapy with special reference to the organization of the spa and health resort-based treatment of the children in the Russian Federation. The main issues discussed by the authors include the current state of health resort care for the children, the problem of statutory regulation of the activities of the children's spa and health resort facilities, the approaches to increasing the availability of the spa and health resort-based treatment for the children at the enhanced risk of the development of chronic diseases, disabilities, and tuberculosis. Also considered are the problems of the development of the regulatory framework for the medical rehabilitation of the children based at the spa and health resort facilities. The principal goals to be sought in climatotherapy, physiotherapy, balneotherapy, and pelotherapy in the pediatric context are outlined along with the further prospects for the development of the main areas of pediatric balneology.

  4. "Roman Baths" in Contemporary Spa Tourism

    Directory of Open Access Journals (Sweden)

    Vesna Merc

    2005-07-01

    Full Text Available The commercialisation of images and symbols from antiquity, so characteristic of Slovenia since its independence, has been reflected over the last decade in spa tourism as well. Since the great crises in the sixties, and especially since the eighties, fifteen Slovene natural health resorts have concentrated on developing wellness and activities programs. This change in orientation has been accompanied by renovations, an expansion of the water surfaces and capacities, and new wellbeing, wellness, spirituality and beauty programs. An analysis of Slovene spas, wellness centres and hotel web pages shows that they frequently offer rooms, usually saunas, which are imitations of the Roman baths. These rooms are usually called "Roman saunas", "Tepidarium", "Caldarium", and "Roman-Irish baths". At Terme Ptuj, Zdravilišče Laško, Šmarješke Toplice, Grand Hotel Palace in Portorož, and Terme Čatež, saunas have been built or renovated in the Roman style. This trend of Roman rooms is a novelty, less than a decade old in Slovenia. The first sauna with a Roman theme, a Roman-Irish bath, was opened in 1997 in the Health and Beauty Centre at Terme Čatež. Modern Roman saunas are very popular, found not only in Slovenia but also in other parts of Europe, especially Germany and Austria. Their popularity has spread from the areas formerly occupied by the Romans to other parts of world, for example the USA and the Republic of South Africa. An analysis of Slovene saunas and wellness centres reveals a well-established trend to recreate certain parts of the Roman baths. This is attempted not only through Roman-style decorations, but also through certain structures particular to the Roman baths, such as the caldarium, tepidarium, and in one case even a laconicum. The approach, however, is highly eclectic, blending Roman, Greek and, above all, modern elements. The purpose of such rooms is to increase the appeal of the spas, while their design is mostly based on

  5. Insulin utilizes the PI 3-kinase pathway to inhibit SP-A gene expression in lung epithelial cells

    Directory of Open Access Journals (Sweden)

    Snyder Jeanne M

    2002-10-01

    Full Text Available Abstract Background It has been proposed that high insulin levels may cause delayed lung development in the fetuses of diabetic mothers. A key event in lung development is the production of adequate amounts of pulmonary surfactant. Insulin inhibits the expression of surfactant protein A (SP-A, the major surfactant-associated protein, in lung epithelial cells. In the present study, we investigated the signal transduction pathways involved in insulin inhibition of SP-A gene expression. Methods H441 cells, a human lung adenocarcinoma cell line, or human fetal lung explants were incubated with or without insulin. Transcription run-on assays were used to determine SP-A gene transcription rates. Northern blot analysis was used to examine the effect of various signal transduction inhibitors on SP-A gene expression. Immunoblot analysis was used to evaluate the levels and phosphorylation states of signal transduction protein kinases. Results Insulin decreased SP-A gene transcription in human lung epithelial cells within 1 hour. Insulin did not affect p44/42 mitogen-activated protein kinase (MAPK phosphorylation and the insulin inhibition of SP-A mRNA levels was not affected by PD98059, an inhibitor of the p44/42 MAPK pathway. In contrast, insulin increased p70 S6 kinase Thr389 phosphorylation within 15 minutes. Wortmannin or LY294002, both inhibitors of phosphatidylinositol 3-kinase (PI 3-kinase, or rapamycin, an inhibitor of the activation of p70 S6 kinase, a downstream effector in the PI 3-kinase pathway, abolished or attenuated the insulin-induced inhibition of SP-A mRNA levels. Conclusion Insulin inhibition of SP-A gene expression in lung epithelial cells probably occurs via the rapamycin-sensitive PI 3-kinase signaling pathway.

  6. State, planning and design of Jodna spa in Novi Sad

    Directory of Open Access Journals (Sweden)

    Garača Vuk

    2012-01-01

    Full Text Available The paper treats the area of Jodna spa in Novi Sad, which largely coincides with Futoški park, making with it the indissoluble unity. The main problem in the functioning of the Jodna psa is the fact that in legal sense Jodna spa does not exists, and in spatial sense there are still all of its content. The case of the paper is Jodna spa area, which includes the Special Hospital for Rheumatic Diseases, Hotel 'Park', Sports Center 'Sajmište' and Futoški park, which integrate them. The question of the Jodna spa planning, as well as the modern city recreation, spa and tourist center, is the goal of this paper. For this purpose it was necessary to show the historical background of the development of Jodna spa, to make the assessment of the state, critically analyze spatial plans which treat it and provide concrete suggestions for its design and equipping.

  7. Staphylococcus aureus spa type t437

    DEFF Research Database (Denmark)

    Glasner, C; Pluister, G; Westh, H

    2015-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) belonging to the multilocus sequence type clonal complex 59 (MLST CC59) is the predominant community-associated MRSA clone in Asia. This clone, which is primarily linked with the spa type t437, has so far only been reported in low numbers among...... included. Most isolates were shown to be monophyletic with 98% of the isolates belonging to the single MLVA complex 621, to which nearly all included isolates from China also belonged. More importantly, all MLST-typed isolates belonged to CC59. Our study implies that the European S. aureus t437 population...

  8. Plan de negocios: Samay Spa Mujer

    OpenAIRE

    Espol; García Viteri, Maria Del Carmen; Valle SÁnchez, Francisco; Pauta, MarÍa Alexandra

    2015-01-01

    Samay spa mujer, diseñado como centro de bienestar, belleza y salud de la mujer guayaquileña ejecutiva, pone a su disposición un ambiente armonioso con soluciones para mantener y mejorar su imagen personal y eliminar el estrés. lograremos que la mujer sienta bienestar, descanso, cuidado de su cuerpo, disfrute de preciosos momentos, a través d eun variado paquete de servicios con el respaldo de equipos modernos de alta tecnología de la conocida maraca española sorisa y productos esteé lauder, ...

  9. Modified Decoding Algorithm of LLR-SPA

    Directory of Open Access Journals (Sweden)

    Zhongxun Wang

    2014-09-01

    Full Text Available In wireless sensor networks, the energy consumption is mainly occurred in the stage of information transmission. The Low Density Parity Check code can make full use of the channel information to save energy. Because of the widely used decoding algorithm of the Low Density Parity Check code, this paper proposes a new decoding algorithm which is based on the LLR-SPA (Sum-Product Algorithm in Log-Likelihood-domain to improve the accuracy of the decoding algorithm. In the modified algorithm, a piecewise linear function is used to approximate the complicated Jacobi correction term in LLR-SPA decoding algorithm. Construct the tangent by the tangency point to the function of Jacobi correction term, which is based on the first order Taylor Series. In this way, the proposed piecewise linear approximation offers almost a perfect match to the function of Jacobi correction term. Meanwhile, the proposed piecewise linear approximation could avoid the operation of logarithmic which is more suitable for practical application. The simulation results show that the proposed algorithm could improve the decoding accuracy greatly without noticeable variation of the computational complexity.

  10. spa typing for epidemiological surveillance of Staphylococcus aureus

    NARCIS (Netherlands)

    Hallin, Marie; Friedrich, Alexander W; Struelens, Marc J; Caugant, Dominique A.

    2009-01-01

    The spa typing method is based on sequencing of the polymorphic X region of the protein A gene (spa), present in all strains of Staphylococcus aureus. The X region is constituted of a variable number of 24-bp repeats flanked by well-conserved regions. This single-locus sequence-based typing method

  11. Spa and Wellness Tourism in Slovakia (A Geographical Analysis

    Directory of Open Access Journals (Sweden)

    Kasagranda Anton

    2017-06-01

    Full Text Available Spa industry is presently an inherent part of Slovak tourism. For this reason, it has become a major interest of scientific and professional literature (economics, management, sociology, or geography. The main topic of this paper is the evaluation of tourism in Slovakia through a geographic analysis. This paper briefly evaluates the development and the importance of spa, spa tourism and wellness and their main research areas and issues. Furthermore, the primary sources of tourism development, the overview of spa tourism and the wellness resorts, the accommodation establishments and the visitation rate are evaluated as well. In conclusion, functional and spatial typification of spa tourism and wellness in Slovakia is presented. The structure of the paper is designed to be appropriate for a comparison with V4 countries.

  12. Effects of balneotherapy and spa therapy on levels of cortisol as a stress biomarker: a systematic review

    Science.gov (United States)

    Antonelli, Michele; Donelli, Davide

    2018-02-01

    Balneotherapy and spa therapy are well-known practices, even though limited evidence has been produced about their biological effects. This systematic review primarily aims at assessing if balneotherapy, mud/peloid therapy, and spa therapy may influence cortisol levels. Secondarily, it aims at understanding if these interventions may improve stress resilience. PubMed/Medline, Embase, and Cochrane Library were searched for relevant articles in English or Italian about studies involving healthy and sub-healthy subjects or patients with a diagnosed disease about effects of balneotherapy, mud/peloid therapy, and spa therapy on serum and salivary cortisol levels. Fifteen studies involving 684 subjects were included. Five studies investigated biological effects of balneotherapy alone. Two of them reported significant changes of cortisol levels in healthy participants. The other three studies reported no significant variations in patients with rheumatic conditions. No studies investigated biological effects of mud/peloid therapy alone. Ten studies investigated biological effects of spa therapy with or without included mud/peloid therapy, and in all but two studies, significant variations of cortisol levels were reported. Our main findings suggest that balneotherapy may have the potential to influence cortisol levels in healthy subjects, in such a way as to improve stress resilience. Spa therapy with or without included mud/peloid therapy demonstrated the same potential to influence cortisol levels also in sub-healthy subjects and in patients with a diagnosed disease. Therefore, balneotherapy and spa therapy may be considered as useful interventions for the management of stress conditions. Further investigation is needed because of limited available data.

  13. SPA (Solus per Aqua) service industry: An entrepeneurship opportunity to beauty education department

    Science.gov (United States)

    Marwiyah, Apriyani, Delta

    2018-03-01

    Beauty industry grows vastly in the scope of regional, national, or international. Beauty industry includes Spa service. It becomes one of the choices where the urban citizen can use it to release their stress and relax their mind. This business grows as the development of technology. Spa industry should be able to provide the best service for physical and mental therapy, it will make the user of the service can be freed from their business and stress in the respective time to be healthies, more beautiful, and able to do their activity maximally. Spa treatment consists of hair creambath, facial treatment, manicure-pedicure, scrub treatment, foot spa, aromatherapy, and body treatment with traditional cosmetics which are easy to get in Indonesia. Beauty education is one of the programs in Home Economics Department of Engineering Faculty of UNNES. This program was established to produce graduates in beauty fields as Vocational High School teachers with bachelor (S1) qualification. The graduates suppose to be excellent, professional, skillful, and care to the environment, culture, and social condition around them. It prepares them as teachers of beauty (in formal and non- formal education). Besides, it also prepared them to have professional competence in production fields of beauty service with adaptive, creative, and innovative which can be entrepreneurs who are able to create job vacancies for others. Beauty education used KKNI- based curriculum, which is oriented to Industry and Working Fields with UNNES' Conservation basis. It provided the students a chance to practive their knowledge in working internship program, study field trip, and teaching practice program. The industry of Spa service provides a big chance to become an entrepreneur, create a working field, and help the government reduce unemployment number, whether from beauty education graduates or from vocational high school students

  14. A new silver based composite material for SPA water disinfection.

    Science.gov (United States)

    Tartanson, M A; Soussan, L; Rivallin, M; Chis, C; Penaranda, D; Lapergue, R; Calmels, P; Faur, C

    2014-10-15

    A new composite material based on alumina (Al2O3) modified by two surface nanocoatings - titanium dioxide (TiO2) and silver (Ag) - was studied for spa water disinfection. Regarding the most common microorganisms in bathing waters, two non-pathogenic bacteria Escherichia coli (Gram-negative) and Staphylococcus epidermidis (Gram positive) were selected as surrogates for bacterial contamination. The bactericidal properties of the Al2O3-TiO2-Ag material were demonstrated under various operating conditions encountered in spa water (temperature: 22-37 °C, presence of salt: CaCO3 or CaCl2, high oxygen content, etc.). Total removal of 10(8) CFU mL(-1) of bacteria was obtained in less than 10 min with 16 g L(-1) of material. Best results were observed for both conditions: a temperature of 37 °C and under aerobic condition; this latest favouring Reactive Oxygen Species (ROS) generation. The CaCO3 salt had no impact on the bactericidal activity of the composite material and CaCl2 considerably stabilized the silver desorption from the material surface thanks to the formation of AgCl precipitate. Preliminary tests of the Al2O3-TiO2-Ag bactericidal behaviour in a continuous water flow confirmed that 2 g L(-1) of material eliminated more than 90% of a 2.0 × 10(8) CFU mL(-1) bacterial mixture after one water treatment recycle and reached the disinfection standard recommended by EPA (coliform removal = 6 log) within 22 h. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Spa treatment of Chernobyl liquidators in Israel

    International Nuclear Information System (INIS)

    Godovich, A.; Chernovskij, A.; Lyass, F.; Shapiro, I.; Kratov, Eh.; Markarov, G.

    1997-01-01

    This paper presents the first experience gained in the use of the unique climate and spa of the Dead Sea for the treatment and rehabilitation of the Chernobyl liquidators at clinic near the city of Arad. Ninety-six patients were treated in Israel, in 40 of these radiation was the etiological factor of the disease: consequences of acute and chronic radiation disease, the astheno-neurotic syndrome, discirculatory encephalopathy, subatrophic laryngopharyngitis, and obstructive bronchitis. Eighty-eight patients had direct indications for treatment at the Dad Sea; locomotory, respiratory, and skin diseases. The course of treatment included the Dad Sea baths, mud applications, sun baths, climatotherapy, physiotherapy, massage, bioenergy therapy, inhalations, moisturizing creams, etc. An appreciable improvement with resolution of the principal symptoms was attained in 82% of patients, in 13% improvement with a significant abatement of the symptoms was achieved, whereas in 5% no apparent results were seen

  16. Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice

    International Nuclear Information System (INIS)

    Haque, Rizwanul; Umstead, Todd M.; Ponnuru, Padmavathi; Guo Xiaoxuan; Hawgood, Samuel; Phelps, David S.; Floros, Joanna

    2007-01-01

    Millions are exposed to ozone levels above recommended limits, impairing lung function, causing epithelial damage and inflammation, and predisposing some individuals to pneumonia, asthma, and other lung conditions. Surfactant protein-A (SP-A) plays a role in host defense, the regulation of inflammation, and repair of tissue damage. We tested the hypothesis that the lungs of SP-A(-/-) (KO) mice are more susceptible to ozone-induced damage. We compared the effects of ozone on KO and wild type (WT) mice on the C57BL/6 genetic background by exposing them to 2 parts/million of ozone for 3 or 6 h and sacrificing them 0, 4, and 24 h later. Lungs were subject to bronchoalveolar lavage (BAL) or used to measure endpoints of oxidative stress and inflammation. Despite more total protein in BAL of KO mice after a 3 h ozone exposure, WT mice had increased oxidation of protein and had oxidized SP-A dimers. In KO mice there was epithelial damage as assessed by increased LDH activity and there was increased phospholipid content. In WT mice there were more BAL PMNs and elevated macrophage inflammatory protein (MIP)-2 and monocyte chemoattractant protein (MCP)-1. Changes in MIP-2 and MCP-1 were observed in both KO and WT, however mRNA levels differed. In KO mice MIP-2 mRNA levels changed little with ozone, but in WT levels they were significantly increased. In summary, several aspects of the inflammatory response differ between WT and KO mice. These in vivo findings appear to implicate SP-A in regulating inflammation and limiting epithelial damage in response to ozone exposure

  17. Post-neonatal drop in alveolar SP-A expression

    DEFF Research Database (Denmark)

    Stray-Pedersen, Arne; Vege, Ashild; Stray-Pedersen, Asbjorg

    2008-01-01

    BACKGROUND: Surfactant protein A (SP-A) is synthesized in the lung and is a part of the innate immune system. The aim of this study was to evaluate the expression of SP-A in lung tissue from fetuses, infants, children and adults with special regard to sudden infant death syndrome (SIDS). METHODS......: A total of 160 cases were studied; 19 fetuses and neonates, 59 SIDS and 49 explained infant deaths below 1 year of age, 19 toddlers and 14 adults. Immunohistochemical detection of SP-A using monoclonal antibodies was performed by microscopy of lung tissue specimens collected at autopsy. A scoring system...

  18. Correlation of the sperm penetration assay (SPA and miscarriage after assisted reproduction: The potential use of spa as a new criterion for preimplantation genetic diagnosis

    Directory of Open Access Journals (Sweden)

    Gradistanac Jelena

    2011-01-01

    Full Text Available We analyzed 93 couples undergoing male screening with the Sperm Penetration Assay (SPA before in vitro fertilization and intracytoplasmic sperm injection (ICSI, to determine the accuracy of SPA for subsequent embryonic development, incidence of pregnancy and miscarriage rates (SAB. ICSI patients with the lowest SPA scores had significantly higher incidences of Sthan did patients in the other SPA groups. Sperm quality is higher with better SPA scores. Poor sperm quality has increased incidence of chromosomal abnormalities and is associated with early fetal loss. Couples with negative SPA are candidates for preimplantation genetic diagnosis, to reduce the incidence of SAB.

  19. The paradigm of territoriality in the spa tourism: The concept of spatial indicators

    Directory of Open Access Journals (Sweden)

    Dželebdžić Omiljena

    2010-01-01

    Full Text Available The famous tradition of spa places like cultural centers and health resorts with unique potential in natural curing springs could be a solid, but not an adequate, ground for their development according to the challenges of contemporary society. The renewed interest in the territorial aspects of tourism as a response to globalization enhanced the influence of spatial factor (tourismscape on current on tourism demand. The network of flows, relationships and interactions, as the core of the territoriality concept, is not something new and unknown in regional planning but requires a new analytical tool for researching the global network connectivity. This paper analyzes the concept of territorial networking in the system of physical, functional and organizational networks as one of the crucial aspects in the development of well balanced tourism region. The consideration aim is to examine and define the relevant indicators that may specify the level of competitiveness of spa region in the global tourism market.

  20. Biological properties of mud extracts derived from various spa resorts.

    Science.gov (United States)

    Spilioti, Eliana; Vargiami, Margarita; Letsiou, Sophia; Gardikis, Konstantinos; Sygouni, Varvara; Koutsoukos, Petros; Chinou, Ioanna; Kassi, Eva; Moutsatsou, Paraskevi

    2017-08-01

    Spa resorts are known for thousands of years for their healing properties and have been empirically used for the treatment of many inflammatory conditions. Mud is one of the most often used natural materials for preventive, healing and cosmetic reasons and although it has been used since the antiquity, little light has been shed on its physical, chemical and biological properties. In this study we examined the effect of mud extracts on the expression of adhesion molecules (CAMs) by endothelial cells as well as their effects on monocyte adhesion to activated endothelial cells. Most of mud extracts inhibited the expression of VCAM-1 by endothelial cells and reduced monocyte adhesion to activated endothelial cells, indicating a potent anti-inflammatory activity. Furthermore, the mud extracts were tested for their antimicrobial activity; however, most of them appeared inactive against S. aureus and S. epidermidis. One of the mud extracts (showing the best stabilization features) increased significantly the expression of genes involved in cell protection, longevity and hydration of human keratinocytes, such as, collagen 6A1, forkhead box O3, sirtuin-1, superoxide dismutase 1 and aquaporin-3. The present study reveals that mud exerts important beneficial effects including anti-inflammatory and anti-aging activity as well as moisturizing effects, implicating important cosmeceutical applications.

  1. Non-spa-typeable clinical Staphylococcus aureus strains are naturally occurring protein A mutants

    DEFF Research Database (Denmark)

    Baum, Cathrin; Haslinger-Löffler, Bettina; Westh, Henrik

    2009-01-01

    Staphylococcus aureus is a major human pathogen responsible for increasing the prevalence of community- and hospital-acquired infections. Protein A (SpA) is a key virulence factor of S. aureus and is highly conserved. Sequencing of the variable-number tandem-repeat region of SpA (spa typing......) provides a rapid and reliable method for epidemiological studies. Rarely, non-spa-typeable S. aureus strains are encountered. The reason for this is not known. In this study, we characterized eight non-spa-typeable bacteremia isolates. Sequencing of the entire spa locus was successful for five strains...... and revealed various mutations of spa, all of which included a deletion of immunoglobulin G binding domain C, in which the upper primer for spa typing is located, while two strains were truly spa negative. This is the first report demonstrating that nontypeability of S. aureus by spa sequencing is due either...

  2. Allegheny County Public Swimming Pool, Hot Tub, and Spa Inspections

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Public swimming pool, hot tub, and spa facilities are licensed and inspected once each year to assure proper water quality, sanitation, lifeguard coverage and...

  3. The design of the spa - tourist recreational complex

    Directory of Open Access Journals (Sweden)

    Alenka Fikfak

    2012-01-01

    Full Text Available The study area lies in the central part of Bela Krajina in south-eastern Slovenia, between the town of Črnomelj and the border crossing at Vinica. It is situated in the vicinity of the Lahinja Landscape Park, where natural and cultural heritage sites interact in the interesting settings of preserved towns and villages. The urban planning concept developed at the workshop was based on the idea that the best space is one where the qualities of "empty spaces" and a fusion with the landscape are recognised. The concept was based on the design of a complex with several connecting structures. A green clearing was defined as the centre of activities, i.e. the core of the activity and pivot of life being the common point of all structures: it is empty, intended to allow for random connections, network organisation or spatial networking, where the key points in the built and natural structures are connected, hence representing the main communication hub between the individual structures. The concept complements the system with accommodation capacities, which are also located outside the spa complex, providing attractive accommodation in a natural setting.

  4. Neuroendocrine-immune and metabolic accompaniments of cholecystokinetic effects of balneotherapy on SPA Truskavets’

    Directory of Open Access Journals (Sweden)

    O M Marfiyan

    2015-05-01

    4Faculty of Physical Education, Health and Tourism, Kazimierz Wielki University, Bydgoszcz, Poland w.zukow@ukw.edu.pl   SUMMARY   Objective. Ability balneofactors spa Truskavets’ (Ukraine, including bioactive water Naftussya, affect Gall-bladder motility has long been known. We set a goal to identify changes related neuroendocrine-immune complex and metabolism accompanying cholecystokinetic effect of balneotherapy on spa. Results. In observation of 22 men with chronic cholecystitis in combination with pyelonephritis, found that 10-12-day course of balneotherapy (drinking of bioactive water Naftussya, application of ozokerite, mineral baths reduces Gall-bladder volume fasting by 16% (p0,05, by increasing PSD HF greater extent than LF. The basal levels of plasma cortisol decreased by 20% (p0,2 and 8% (p<0,05 respectively. Regarding immunity parameters revealed significant increase in blood CD16+ lymphocytes only (+17%, p<0,01 in the absence of changes in levels of CD3+CD4+ and CD3+CD8+ T cells and CD19+ B lymphocytes. Do not change significantly either serum Igg G, M, A, or circulating immune complexes. Finally, stated a slight but significant increase electrokinetic index cell nuclei of buccal epithelium, indicating the "rejuvenation" of the body. Conclusion: balneotherapy on spa Truskavets’ be significantly cholecystokinetic effect, combined with the activation excretory and depurative kidney functions and neutrophil bactericidal function against a background of lower levels of neuroendocrine markers of stress. Keywords: Truskavets’, balneotherapy, cholekinetic, diuresis, neuroendocrine-immune complex.

  5. Removal of linear alkylbenzene sulfonate (LAS) and its intermediate, sulfophenylalkanoates (spa) using a bioreactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, In Ku [Seoul National Univ., Seoul (Korea, Republic of); Kim, Ji Hyeon; Yoo, Young Je [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Kim, Hwa Yong [Seoul National Univ., Seoul (Korea, Republic of)

    1995-12-01

    A fluidized-bed bioreactor was used to treat the industrial wastewater containing linear alkylbenzene sulfonate(LAS). Microorganism obtained by acclimation showed low growth rate and substrate inhibition at relatively high substrate concentration. It was found from the experiment using fluidized-bed bioreactor that 64 {mu}m-thick biofilm was made after 15 days. The 93.4% LAS removal efficiency in the reactor was obtained at 120 mg/L of initial LAS concentration, while the removal efficiency of sulfophenylalkannoates(SPA) which is a representative intermediate of biodegradation of LAS was 60-88% depending on the initial concentration of LAS. When sodium benzoate was added to the second reactor, the remaining SPA became lowered by 40% compared to the control experiment. And when activated carbon was added to the reactor, the removal efficiency of SPA was 96.2% and that of LAS was 100% when initial inflowing concentration of LAS was 350 mg/L. 13 refs., 4 tabs., 8 figs.

  6. SPA AND CLIMATIC RESORTS (CENTERS AS RESOURCES OF PROGRAM OF SPORT RECREATION IMPLEMENTATION

    Directory of Open Access Journals (Sweden)

    Ivica Nikolić

    2006-06-01

    Full Text Available The aspiration of the civilized man is the improvement of work which aim is to achieve as big as possible effect of productivity and as small as possible participation of labour. The result of this process, which cannot be avoided, is some kind of fatigue that has hypocinaesiological characteristics in regard to demands of modern work process. The most effective way to fight against fatigue is to have an active holiday that is meaningfully programmed, led and carried out through movement of tourists, with the addition of natural factors, among which climate and healing waters are particularly important. These very resources characterize the tourist potential of Serbia and Montenegro with lots of available facilities at 1000 m height above the sea level and spa centers with springs and a complete offer physio-prophylactic procedures and following facilities for sport recreation. The implementation of programmed active holidays in to the corpus of tourist offer of Serbia and Montenegro represents prospective of development of tourism and tourist economy with effects of multiple importance as for participants, so for the level of tourist consumption. That will definitely influence the lengthening of tourist season as the primary goal of every catering establishment. Surveys show that the affection and viewpoints of potential tourists are especially directed towards engaging sport games and activities on and in the water, as part of the elementary tourist offer in spas and climatic resorts and their available facilities. Recommendationsand postulates of program of sport recreation, which are presented through four charts, are the basis of marketing strategy of appearance on tourist market with permanent education of management personnel and further research of potential market expanding. The publication and distribution of advertising materials are especially important, both at the market in our country and at the foreign market, where the abundance

  7. Spa as Arena of Career Woman Resistance to Patriarch Domination

    Directory of Open Access Journals (Sweden)

    Bhernadetta Pravita Wahyuningtyas

    2011-04-01

    Full Text Available This study examines the career women who use the habit of treating the body through the routine of coming to spas, which aims to overcome the dominance of patriarchy. This study uses several concepts. First, muted group theory, which states that woman, is the one that silenced; so to overcome this condition, women should perform self-transformation. The transformation is aligned with the second concept, feminist existentialist, which defines the transformation as the change of a woman concept from Other to Self. The transformation can be achieved not only by working outside the domestic sphere, but also supported by a good appearance through a complete body treatment. Grooming habits acquired through socialization that derived in woman since their childhood. The socialization is about how women as a person who is considered weak by the world of patriarchal domination using the power of their beauty to master, subdue, and break the domination in her life. Then, with their good appearance, woman can express their existence in everything that they do from object become subject. Spa and the whole result of the activities contained in it then consciously become a way of resistance that being used by the career woman against the domination of patriarchy which overshadowing their lives. 

  8. Study of spa and geology in Nagano pref

    Energy Technology Data Exchange (ETDEWEB)

    Iijima, Namio

    1987-03-20

    After due consideration of magma activities, spars and the horizontal movement involved in the formation of the Japanese Archipelago, magma generation and plate theory under the Japanese Archipelago were studied comprehensively. Many spars in the Japanese North Alpine mountains, which are located in old rock areas, were mainly gushed out from new-period granite. Thus, they were presumed to be caused by volcanos from Hakuba-Norikura to Ontake. There are also several spas on the Central Upheaval Zone which are new lock area spas. This zone is characterized by focused volcanism which occurred during the time from the Tertiary period to the Quaternary period of the diluival epoch. Especially, the northern part of the zone has many high-temperature spas above 50/sup 0/C. Moreover, at the southern end of this zone, special geological features which prove that the Philippine plate and the Pacific plate are sunk under the Japanese Archipelago were found. It was also estimated that Nagano Prefecture has no spa caused by volcanism of acidic plutonic rocks from the the later Mesozoic era to the early Cenozoic era. (3 figs, 1 tab, 27 refs)

  9. Hypersensitivity pneumonitis with Mycobacterium avium complex among spa workers.

    Science.gov (United States)

    Moraga-McHaley, Stephanie Ann; Landen, Michael; Krapfl, Heidi; Sewell, C Mack

    2013-01-01

    The New Mexico Department of Health (NMDOH) investigated the cause of two cases of hypersensitivity pneumonitis (HP) in spa maintenance workers with laboratory confirmed Mycobacterium avium complex (MAC). The investigation occurred in tandem with worker protection and swimming pool regulatory investigations by the New Mexico Environment Department at the spa where the workers were employed. The investigation was conducted in order to identify unreported cases, exposure source(s), and to prevent further worker exposure. NMDOH surveyed 57 spa employees about symptoms and exposures, categorized jobs according to self-reported exposure to water, and computed odds ratios for symptom reporting by exposure category. Environmental isolates from spa water and filter swabs were cultured and compared to patient isolates by the Environmental and Applied Microbiology Team, Centers for Disease Control and Prevention (CDC). Workers with the highest exposure reported more HP-like symptoms (OR = 9.6), as did intermediate exposure workers (OR = 6.5), compared to workers with no aerosolized water exposure. Two of 13 environmental isolates were closely related to one of the patient isolates. Workers were likely exposed during spray cleaning of cartridge filters in a poorly ventilated work space. Recommendations include inhibiting organism growth in spa systems, assuring the use of respiratory protection, and adequately ventilating work spaces where filters and equipment are cleaned.

  10. Microfibril-associated Protein 4 Binds to Surfactant Protein A (SP-A) and Colocalizes with SP-A in the Extracellular Matrix of the Lung

    DEFF Research Database (Denmark)

    Schlosser, Anders; Thomsen, Theresa H.; Shipley, J. Michael

    2006-01-01

    for phagocytes. Here we describe the molecular interaction between the extracellular matrix protein microfibril-associated protein 4 (MFAP4) and SP-A. MFAP4 is a collagen-binding molecule containing a C-terminal fibrinogen-like domain and a N-terminal located integrin-binding motif. We produced recombinant MFAP4......-A composed of the neck region and carbohydrate recognition domain of SP-A indicating that the interaction between MFAP4 and SP-A is mediated via the collagen domain of SP-A. Monoclonal antibodies directed against MFAP4 and SP-A were used for immunohistochemical analysis, which demonstrates that the two...... molecules colocalize both on the elastic fibres in the interalveolar septum and in elastic lamina of pulmonary arteries of chronically inflamed lung tissue. We conclude, that MFAP4 interacts with SP-A via the collagen region in vitro, and that MFAP4 and SP-A colocates in different lung compartments...

  11. Influence of Aging on Plasma Renin Activity

    International Nuclear Information System (INIS)

    Cho, K. W.; Kim, S. H.; Kang, S. K.; Choi, H. Y.

    1982-01-01

    Influence of aging on plasma renin activity was evaluated in healthy normotensive subjects(age range 21-63 years, 413 males) devoid of cardiorenal or endocrinological problems. The age-related decrease of plasma renin activity in the subjects between 21-28 years group and 36-42 years group was slight, but over the 43 years groups was significantly different. The age-related suppression of plasma renin activity was much more smooth and continuous all over the age ranges evaluated. The sexual difference in plasma renin activity was noticed between the subjects of 22 years old group (34 males) and 19 years group (34 females) (p<0.003). The data suggest that the age-related suppression of plasma renin activity appeared in healthy normotensive subjects should be considered in the case of evaluation of low renin essential hypertension.

  12. [Spa-based water procedures and complications in the course of their performance].

    Science.gov (United States)

    Persiianova-Dubrova, A L; Badalov, N G; L'vova, N V; Krikorova, S A; Tupitsyna, Iu Iu; Uianaeva, A I; Barashkov, G N; Povazhnaia, E L

    2010-01-01

    The scope of applications of spa-based water procedures have become considerably extended during the recent years; accordingly, the frequency of complications and accidents has increased. The present review considers the possible mechanisms underlying such complications and various factors promoting their development, such as the patients' age and chronic diseases, the use of pharmaceutical products affecting thermoregulation and cardiovascular function. Special attention is given to the influence of alcohol consumption on the frequency of complications, accidents, and sudden death associated with hyperthermal procedures, the possibility of infectious diseases and measures necessary for their prevention.

  13. Non-spa-typeable clinical Staphylococcus aureus strains are naturally occurring protein A mutants

    DEFF Research Database (Denmark)

    Baum, Cathrin; Haslinger-Löffler, Bettina; Westh, Henrik

    2009-01-01

    Staphylococcus aureus is a major human pathogen responsible for increasing the prevalence of community- and hospital-acquired infections. Protein A (SpA) is a key virulence factor of S. aureus and is highly conserved. Sequencing of the variable-number tandem-repeat region of SpA (spa typing) prov...

  14. Perceptual incongruence influences bistability and cortical activation.

    Directory of Open Access Journals (Sweden)

    Gijs Joost Brouwer

    Full Text Available We employed a parametric psychophysical design in combination with functional imaging to examine the influence of metric changes in perceptual incongruence on perceptual alternation rates and cortical responses. Subjects viewed a bistable stimulus defined by incongruent depth cues; bistability resulted from incongruence between binocular disparity and monocular perspective cues that specify different slants (slant rivalry. Psychophysical results revealed that perceptual alternation rates were positively correlated with the degree of perceived incongruence. Functional imaging revealed systematic increases in activity that paralleled the psychophysical results within anterior intraparietal sulcus, prior to the onset of perceptual alternations. We suggest that this cortical activity predicts the frequency of subsequent alternations, implying a putative causal role for these areas in initiating bistable perception. In contrast, areas implicated in form and depth processing (LOC and V3A were sensitive to the degree of slant, but failed to show increases in activity when these cues were in conflict.

  15. Pürovel Spa & Sport / Ülli Plink

    Index Scriptorium Estoniae

    Plink, Ülli, 1973-

    2011-01-01

    Swissôtel Tallinna 11. korrusel asuvast Pürovel Spa & Sport poolt pakutavatest treeningutest ning lõõgastusprotseduuridest, samuti 8. korrusel asuvast a la carte menüü ja päevabuffega restoranist Café Swiss

  16. Parental Influence on Young Children's Physical Activity

    Directory of Open Access Journals (Sweden)

    Cheryl A. Zecevic

    2010-01-01

    Full Text Available Parents influence on their young children's physical activity (PA behaviours was examined in a sample of 102 preschool-aged children (54 boys. Questionnaires regarding family sociodemographics and physical activity habits were completed. Results showed that children who received greater parental support for activity (B=.78, P<.10 and had parents who rated PA as highly enjoyable (B=.69, P<.05 were significantly more likely to engage in one hour or more of daily PA. Being an older child (B=−.08, P<.01, having older parents (B=−.26, P<.01, and watching more than one hour of television/videos per day (B=1.55, P<.01 reduced the likelihood that a child would be rated as highly active. Children who received greater parental support for PA were 6.3 times more likely to be highly active than inactive (B=1.44, P<.05. Thus, parents can promote PA among their preschoolers, not only by limiting TV time but also by being highly supportive of their children's active pursuits.

  17. [Effects of drinking spa therapy on oxidative stress].

    Science.gov (United States)

    Costantino, M; Giampaolo, C; Filippelli, A

    2012-01-01

    Data of literature have shown the correlation between oxidative stress and some diseases of gastrointestinal and metabolic relevance such as diabetes mellitus, gastric cancer, gastritis, etc.. Studies have also shown that sulfurous mineral water may be useful in the treatment of gastrointestinal diseases. The aim of our research was to evaluate the antioxidant effect of sulphurous mineral water, administered by drinking method, in type 2 diabetes mellitus, a chronic disease with a high social and economic impact. The study has been performed on 57 subjects (25% women and 75% males; mean age: 60 ± 1.1 years; BMI: 27 ± 0.4) affected by type 2 Diabetes Mellitus. The subjects were divided in four groups: A (subjected to glucose-lowering diet therapy), B (subjected to antihyperglycaemic therapy), C (exposed to glucose-lowering diet therapy + drinking SPA therapy) and D (exposed to antihyperglycaemic therapy + drinking SPA therapy). Drinking SPA treatment was effected with sulphurous mineral water from Terme of Telese SpA (Benevento - Italy) and the pharmacological treatment provided the use of hypoglycemic drugs normally used in diabetic disease. After two weeks of therapy with treatments considered were evaluated fasting blood glycaemia and plasma concentration of ROMs (reactive oxygen metabolites) (d-ROMs test-Diacron International srl®-Grosseto - Italy). The results of our study have shown a significant (pfasting blood glycaemia when to hypoglycemic drugs or diet therapy was associated the sulphurous drinking SPA therapy. It was also observed a reduction of plasma ROMs levels, significant (p water, especially in combination with antidiabetic drug treatment, may be useful in type 2 diabetes mellitus for the improvement redox state of the organism.

  18. Rehabilitation of patients with rheumatoid arthritis treated in stationary spa treatment

    Directory of Open Access Journals (Sweden)

    Amila Jaganjac

    2015-04-01

    Full Text Available Introduction: Rheumatic diseases are nonsurgical diseases of the locomotor system and connective tissue. Rheumatoid arthritis (RA is a systemic inflammatory disease of connective tissue of unknown cause, with progressive chronic or subacute course. The aim of the research is to determine whether stationary spa treatment leads to improvement of the functional status in patients with rheumatoid arthritis. Methods: We included 35 patients with diagnosis of rheumatoid arthritis, referred for treatment at the spa " Ilidža " Gradačac from February to April 2014. Patients not adhering to treatment protocols were excluded. We used Visual analogue pain scale (VAS, HAQ questionnaire and assessment of the clinical condition before and after the treatment based on the scores 1-5.Results: There were 32 female and 3 male patients. The average age was 62.28±8.31 years. Based on the HAQ, 12 patients had no difficulties, 9 of them perform activities with little difficulties, 10 with many difficulties, and 4 patients cannot perform certain activities. Before treatment VAS was 6.63±2.36, and after treatment the 2.51±2.27. Ratings of clinical condition before treatment was 2.38±0.74, and after the treatment 3.64±0.98. The most frequently used therapies were kinesitherapy, magnetotherapy and interferential electricity. Conclusions: Stationary treatment at the spa „Ilidža“ Gradačac leads to an improvement of the functional status in patients with rheumatoid arthritis.

  19. The spa typing of methicillin-resistant Staphylococcus aureus isolates by High Resolution Melting (HRM) analysis.

    Science.gov (United States)

    Fasihi, Yasser; Fooladi, Saba; Mohammadi, Mohammad Ali; Emaneini, Mohammad; Kalantar-Neyestanaki, Davood

    2017-09-06

    Molecular typing is an important tool for control and prevention of infection. A suitable molecular typing method for epidemiological investigation must be easy to perform, highly reproducible, inexpensive, rapid and easy to interpret. In this study, two molecular typing methods including the conventional PCR-sequencing method and high resolution melting (HRM) analysis were used for staphylococcal protein A (spa) typing of 30 Methicillin-resistant Staphylococcus aureus (MRSA) isolates recovered from clinical samples. Based on PCR-sequencing method results, 16 different spa types were identified among the 30 MRSA isolates. Among the 16 different spa types, 14 spa types separated by HRM method. Two spa types including t4718 and t2894 were not separated from each other. According to our results, spa typing based on HRM analysis method is very rapid, easy to perform and cost-effective, but this method must be standardized for different regions, spa types, and real-time machinery.

  20. Impact to Tourism Industry of Massage Spa Therapy in Batangas City, Philippines

    Directory of Open Access Journals (Sweden)

    Kimmy Lei T. Atienza

    2014-10-01

    Full Text Available This study aimed to assess the benefits of massage spa therapy in tourism industry of Batangas City and their adherence to the standards to DOT on Spa operation and maintenance. The study aimed to identify the profile of massage spa in terms of type of ownership, length of years in the business, type of spa and different spa services offered; to assess the benefits of massage spa to the tourism industry; and to determine the extent of adherence of the massage spa to DOT standards about spa operation and maintenance; and propose a plan of action based on the results of the study. Descriptive method was used in the study. Results showed that the Sole Proprietorship got the highest rank in terms of type of ownership. With the length of years in service, it shows that most of spa business already exists for 4-6 years. Type of spa shows that majority of the spa business were Spa Town. With regards to different spa services, majority offers peat pulp bath and the least is sauna and steam bath. The over-all assessment of the respondents’ on the benefits of spa was agree by the result. It was also observed that all items were assessed as agree and it enhances the awareness of the tourists about the beauty of Batangas City. It was followed by provide taxes for the government, became a tourist attraction and improves socio-economic of local residents and improvement on the lifestyle both of the local residents and tourists

  1. Natural radioactivity in mineral and spa water: the current regulatory approach in Italy

    International Nuclear Information System (INIS)

    Nuccetelli, C.; Bochicchio, F.; Ruocco, G.

    2004-01-01

    Mineral and thermal waters can contain radioactivity of natural origin which, in some cases, can lead to radiation-protection problems for both workers and consumers. In Italy, as in many other countries, the consumption of bottled mineral water is rather high and the practice of spending short stays in spas is also popular. Consumer protection against natural radioactivity in mineral water is not regulated at all and exposure from thermal waters is not treated in detail, in either the European Union or Italy. For this reason, the Italian Ministry of Health - which has the duty to authorize spa activities and the sale of mineral water on the basis of water characteristics - asked the Istituto Superiore di Sanita (the Italian National Institute of Health) to provide ad-hoc reports containing both dosimetric calculations and analysis of the radiation-protection regulations to be applied in these situations. On the basis of these reports, the Ministry of Health decided, in two statements for spa and mineral waters respectively, to indicate upper levels for natural radioactivity content. Since 2002, spa water parameters have been in force for authorization of their use and sale, and are to be promulgated by specific and more comprehensive regulations. For mineral waters used for infant feeding and drinking, levels lower than those for general public uses have been proposed, in order to take into account the higher ingestion dose coefficients for infants. At the moment, mineral water levels are not enforced as law. This paper presents the dosimetric calculation results and the Ministry of Health statements. (Author) 17 refs

  2. Influences of climacteric in female sexual activity

    Directory of Open Access Journals (Sweden)

    Anthonio Alisancharles Batista de Almeida

    2016-01-01

    Full Text Available Objective: to identify complaints of sexual function related to climacteric symptoms among women in climacteric age. Methods: this is an descritive study. A sample of 330 women aged from 35 to 65 years old, with three previous Pap tests. We used a semi-structured questionnaire developed by the researchers. A descriptive statistical analysis was performed having the central tendency of proportion and measure the average as a parameter. Results: it was evidenced that 50.0% were between 35-45 years, 73.0% were sexually active, 59.4% had decreased libido, and 58.5% reported dyspareunia. Conclusion: it is necessary that the health services and professionals are aware of the influence of climacteric on women’s health to develop strategies aimed at quality of life.

  3. Spa Garden in Daruvar – Methods of Renewal and Reconstruction

    Directory of Open Access Journals (Sweden)

    Šćitaroci Mladen Obad

    2014-12-01

    Full Text Available Spa garden in Daruvar ‘Julius’s Park’ is the oldest spa garden in continental Croatia. The counts Jankovich and their successors created the garden during the 18th and 20th century. The garden resumed its nowadays form and surface in the time of count Julius Jankovich in the mid-19th century and it was named after him. The garden is protected as a cultural heritage. The garden’s renovation is seen as an urban, architectural and landscape unity and it attempts to affirm the missing and neglected parts of the garden, to provide technological and municipal space modernization and to make a pleasant urban garden ambiance with new facilities and high space arrangement qualities, contributing to the economic development of the local community.

  4. Actividad Físico - Deportiva en Adolescentes Consumidores de SPA

    OpenAIRE

    Tarqui Silva, Leonardo Eliecer; Universidad Estatal de Milagro - Guayaquil Ecuador

    2017-01-01

    RESUMEN El presente estudio muestra el abordaje terapéutico fundamentado en actividades físico-deportivas aplicadas como reforzador, canalizador y modificador conductual en conjunto con terapias cognitivas, socio-humanísticas, espirituales, ocupacionales, vivenciales y familiares ejecutadas en adolescentes consumidores de sustancias psicoactivas (SPA) entre las edades de 14 a 17 años en la Comunidad Terapéutica para Adolescentes Varones Hogar Crecer (CTHC), de la ciudad de Cuenca - Ecuador; o...

  5. Actividad Físico - Deportiva en Adolescentes Consumidores de SPA

    OpenAIRE

    Tarqui Silva, Leonardo Eliecer

    2017-01-01

    RESUMEN El presente estudio muestra el abordaje terapéutico fundamentado en actividades físico-deportivas aplicadas como reforzador, canalizador y modificador conductual en conjunto con terapias cognitivas, socio-humanísticas, espirituales, ocupacionales, vivenciales y familiares ejecutadas en adolescentes consumidores de sustancias psicoactivas (SPA) entre las edades de 14 a 17 años en la Comunidad Terapéutica para Adolescentes Varones Hogar Crecer (CTHC), de la ciudad de Cuenca - Ecuador; o...

  6. SPA Adición de enmiendas a suelos contaminados

    OpenAIRE

    Madejón, Paula

    2016-01-01

    SPA Adición de enmiendas a suelos contaminados.-- Información introducida en la base de datos WOCAT es una red global de gestión sostenible de tierras (SLM) que promueve la documentación, el intercambio y el uso del conocimiento para apoyar la adaptación, la innovación y la toma de decisiones en SLM.

  7. Hydrogeothermal characteristics of groundwater from Ribarska Banja spa, central Serbia

    Directory of Open Access Journals (Sweden)

    Dragišić Veselin S.

    2015-01-01

    Full Text Available Ribarska Banja spa is one of the most popular balneotherapy and recreation centers in Serbia. It features several thermal groundwater sources whose temperatures range from 26 to 54°C. The mineral content of these waters is low and their composition is of the SO4-Na or HCO3-Na type. Thermal water exploration has been conducted in the general area for many years, to assess the hydrogeothermal potential in order to extract larger amounts of thermal water for multiple uses. The hydrogeothermal system of Ribarska Banja spa was defined based on a synthesis of the results of comprehensive structural geology, geophysical, hydrogeological, hydrochemical and geothermal research. The primary groundwater reservoir of the hydrogeothermal system is comprised of tectonic zones (systems of faults and fractures within Cretaceous-Paleogene metamorphosed and non-metamorphosed rocks. The overlying hydrogeological and temperature barrier is made up of a series of low metamorphosed rocks (chlorite, chlorite-sericite schists, gabbros, etc., highly metamorphosed rocks (gneisses and Neogene clay and sand sediments. The system is recharged by infiltration of atmospheric precipitation and surface water at the highest elevations of Mt. Jastrebac. Investigations have also shown that the system’s heat source is younger granitoide intrusion spreading northwest of Ribarska Banja spa. Based on the quartz geothermometers, expected reservoir temperatures are in the range of 85-97°C that can be expected at a depth of 1.87 km. Total energy usage at Ribarska Banja spa is 31 TJ/y with thermal capacity of 1.65 MWt and utilization factor of 0.58. Geothermal gradient is 0,051°C/m, while heat flow density is 163.5 mW/m2. [Projekat Ministarstva nauke Republike Srbije, br. 43004

  8. Fibromyalgia Syndrome and Spa Therapy: Myth or Reality?

    Directory of Open Access Journals (Sweden)

    Giacomo M. Guidelli

    2012-01-01

    Full Text Available Fibromyalgia syndrome (FS is a common musculoskeletal disorder characterized by otherwise unexplained chronic widespread pain, a lowered pain threshold, high tender point counts, sleep disturbances, fatigue, headache, irritable bowel syndrome, morning stiffness, paraesthesias in the extremities, often psychological distress and depressed mood. Consequently, FS has a negative impact on working capacity, family life, social functioning and quality of life. Because of unknown etiology and not clearly understood pathogenesis, there is no standard therapy regime for FS. A variety of medical treatments, including antidepressants, opioids, analgesic or non-steroidal anti-inflammatory drugs, sedatives, muscle relaxants and antiepileptics, have been used to treat FS. Currently, no pharmacological treatment for FS is consistently successful. According to recent guidelines, the optimal treatment of FS requires a multidisciplinary approach with a combination of non-pharmacological and pharmacological treatment modalities. Spa therapy is a popular treatment for FS in many European countries, as well as in Japan and Israel. However, despite their long history and popularity spa treatments are still the subject of debate and their role in modern medicine is still not clear. The objective of this review is to summarize the currently available information on clinical effects and mechanism of action of spa therapy in FS. We also provide some suggestions for further development in this area.

  9. Radioactivity of water and air in Misasa Spa, Japan

    International Nuclear Information System (INIS)

    Morinaga, H.; Mifune, M.; Furuno, K.

    1984-01-01

    Misasa Spa is one of the most highly radioactive hot springs in Japan, the waters of which contain mainly 222 Rn (437 +- 132 Bq.litre -1 ). Radon contents of indoor air of private houses and health resort hotels (built of wood) at Misasa Spa range from 18.5 to 55.5 mBq.litre -1 and 22.2 to 129.5 mBq.litre -1 , respectively. Radon contents in the air of facilities using spring waters at Misasa Branch Hospital of Okayama University were measured to be: bathroom 807 +- 78 mBq.1 -1 , Hubbard-tank bathroom, 5306 +- 2568 mBq.litre -1 ; the drinking hall, 1491 +- 178 mBq.litre -1 . The environmental and dose rate inside private houses has been measured to be 14.0 +- 1.8 μR.h -1 . Chromosome abberations (dicentrics) in the peripheral blood lymphocytes of residents of Misasa Spa were investigated in 14 persons; the mean value of aberration frequencies were 0.21%. (author)

  10. Radioactivity and chromosome aberrations of residents of Misasa Spa

    International Nuclear Information System (INIS)

    Morinaga, Hiroshi; Mifune, Masaaki; Furuno, Katsushi

    1985-01-01

    Misasa Spa is one of the most highly radioactive hot springs in Japan, the waters of which contain mainly 222 Rn (437 ± 132 Bq/liter). Radon contents of indoor air of private houses and health resort hotels (built of wood) at Misasa Spa range from 18.5 to 55.5 mBq/liter and 22.2 to 129.5 mBq/liter, respectively. Radon contents in the air of facilities using spring waters at Misasa Branch Hospital of Okayama University were measured to be; bathroom 807 ± 78 mBq/liter; Hubbardtank bathroom 5306 ± 2568 mBq/liter; the drinking hall 1491 ± 178 mBq/liter. The environmental and dose rate inside private house's has been measured to be 14.0 ± 1.8 μR/h. Chromosome aberrations (dicentrics) in the peripheral blood lymphocytes of residents of Misasa Spa were investigated in 14 persons; the mean value of aberration frequencies were 0.21 %. (Kubozono, M.)

  11. Willingness of patients with ankylosing spondylitis to pay for inpatient treatment is influenced by the treatment environment and expectations of improvement

    NARCIS (Netherlands)

    Boonen, A.; Severens, J. L.; van Tubergen, A.; Landewé, R.; Bonsel, G.; van der Heijde, D.; van der Linden, Sj

    2005-01-01

    Objective: To assess the willingness to pay (WTP) for treatment in a spa resort of patients with ankylosing spondylitis ( AS) and to assess if the experience of a spa influences the WTP. Methods: 120 patients participating in a randomised trial comparing 3 weeks' treatment in a spa resort in Austria

  12. Dual Stimuli-Responsive P(NIPAAm-co-SPA Copolymers: Synthesis and Response in Solution and in Films

    Directory of Open Access Journals (Sweden)

    Oliver Grimm

    2018-06-01

    Full Text Available We present the synthesis and solution properties of dual stimuli-responsive poly(N-isopropylacrylamide-co-spiropyran acrylate (P(NIPAAm-co-SPA copolymers of varying composition prepared via nitroxide-mediated copolymerization. The resulting copolymers feature molar masses from 40,000 to 100,000 g/mol according to static light scattering and an SPA content of up to 5.3%. The latter was determined by 1H NMR spectroscopy and UV–Vis spectroscopy. These materials exhibit reversible response upon irradiation in polymeric films for a minimum of three cycles; their response in solution to both light and temperature was also investigated in an aqueous TRIS buffer (pH 8. Irradiation was carried out using LED setups with wavelengths of 365 and 590 nm. In aqueous solution, a custom-made setup using a fiber-coupled 200 W Hg(Xe lamp with 340 and 540 nm filters was used and additional heating of the copolymer solutions during irradiation allowed to study influence of the presence of either the spiropyran or merocyanine form on the cloud point temperature. Hereby, it was found that increasing the SPA content leads to a more pronounced difference between both states and decreasing cloud points in general.

  13. What influences buying leisure services coupons on online group buying?

    OpenAIRE

    Langvinienė, Neringa; Zemblytė, Jurgita; Sližienė, Gelminė

    2016-01-01

    Growing use of IT, laptops, tablets, PC in individuals' life shaped an opportunity to create online group buying (OGB) as a new online business model. Several of surveys show that OGB is rather popular for selling recreational activities and leisure services, such as restaurant coupons, cinema, spa, concert, flight tickets, museum visits, etc. Therefore, the paper aims to identify and estimate the influences that affect the customers to purchase the leisure services coupons on online group bu...

  14. Waste heat utilization in the thermal spa of Lavey-les-Bains

    International Nuclear Information System (INIS)

    2004-01-01

    This final report for the Swiss Federal Office of Energy looks at the possibilities for improved waste water utilization in the Lavey-les-Bains thermal spa, Switzerland. According to the regulations in force, the temperature of the waste water rejected into the Rhone river shall not exceed 30 o C, what is currently not the case. Also the operational cost shall be reduced and the waste water quality improved. The installations are presented. From the two geothermal wells, mineral water comes out at an average flow rate of 940 l/min and a temperature of 63 o C. Actual waste water data are reported. The measured thermal water consumption data, including seasonal variations, are analysed by computerized simulation and measures to reduce the consumed volume by the optimization of internal procedures are evaluated. Measures to reduce the quantity of the rejected free chlorine are discussed. Several possible adaptations of the existing space heating, domestic water heating and pools' heating are evaluated, including cost. In addition, extensions of the thermal spa center to recreational activities are discussed, as the construction of a tropical greenhouse is

  15. Radium removal from Australian spa waters

    International Nuclear Information System (INIS)

    Dickson, B.L.; Meakins, R.L.; Bland, C.J.

    1982-01-01

    The dissolved radium content of some mineral spring waters in Victoria and Queensland has been found to exceed the maximum permissible concentration in drinking water. Activities in excess of 40 pCi/1 were measured in some bottles. Studies revealed that the dissolved radium content decreased markedly if the spring water was aerated and filtered prior to bottling. The sediment removed contained ferric hydroxide which is a natural scavenging agent for radium. The formation of such sediments in storage tanks and their removal prior to bottling may create a possible radiation hazard

  16. Variations in spa types found in consecutive MRSA isolates from the same patients

    DEFF Research Database (Denmark)

    Boye, Kit; Westh, Henrik

    2010-01-01

    Very little is known about how the spa gene mutates over time in methicillin-resistant Staphylococcus aureus (MRSA) from the same patient. Copenhagen is an area with low prevalence of MRSA but with high variability in spa types. We collected 1536 MRSA isolates from 319 patients during a 5-year...... period and found spa type alterations in 30 MRSA isolates (2%) from 13 patients (4%). The alteration most often seen was the deletion of repeats followed by repeat duplication and point mutation....

  17. CoSpa: A Co-training Approach for Spam Review Identification with Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Wen Zhang

    2016-03-01

    Full Text Available Spam reviews are increasingly appearing on the Internet to promote sales or defame competitors by misleading consumers with deceptive opinions. This paper proposes a co-training approach called CoSpa (Co-training for Spam review identification to identify spam reviews by two views: one is the lexical terms derived from the textual content of the reviews and the other is the PCFG (Probabilistic Context-Free Grammars rules derived from a deep syntax analysis of the reviews. Using SVM (Support Vector Machine as the base classifier, we develop two strategies, CoSpa-C and CoSpa-U, embedded within the CoSpa approach. The CoSpa-C strategy selects unlabeled reviews classified with the largest confidence to augment the training dataset to retrain the classifier. The CoSpa-U strategy randomly selects unlabeled reviews with a uniform distribution of confidence. Experiments on the spam dataset and the deception dataset demonstrate that both the proposed CoSpa algorithms outperform the traditional SVM with lexical terms and PCFG rules in spam review identification. Moreover, the CoSpa-U strategy outperforms the CoSpa-C strategy when we use the absolute value of decision function of SVM as the confidence.

  18. The Role and Importance of Spa and Wellness Tourism in Hungary's Tourism Industry

    Directory of Open Access Journals (Sweden)

    Csapó János

    2017-06-01

    Full Text Available This paper presents and highlights the role and importance of spa and wellness tourism in Hungary. Ever since tourism has played an important role in the social-economic processes of the country the leading tourism product proved to be health tourism (spa and wellness thanks to the advantageous physical geographical and social-political background. After the presentation of the country-specific theoretical system of spa and wellness, the paper examines the supply and the demand side together with competitor analysis and recent trends in spa and wellness in Hungary.

  19. Surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis

    OpenAIRE

    Rintahaka, Johanna; Yu, Xia; Kant, Ravi; Palva, Airi; von Ossowski, Ingemar

    2014-01-01

    A noticeable genomic feature of many piliated Gram-positive bacterial species is the presence of more than one pilus-encoding operon. Paradigmatically, the gut-adapted Lactobacillus rhamnosus GG strain contains two different fimbrial operons in its genome. However, whereas one of these operons (called spaCBA) is encoding for the functionally mucus-/collagen-binding SpaCBA pilus, for the other operon (called spaFED) any native expression of the SpaFED-called pili is still the subject of some u...

  20. A pilot study to evaluate the effects of floatation spa treatment on patients with osteoarthritis.

    Science.gov (United States)

    Hill, S; Eckett, M J; Paterson, C; Harkness, E F

    1999-12-01

    To conduct a preliminary investigation of the effects on floatation spa therapy on quality of life in patients with osteoarthritis to see if controlled trials are warranted. Uncontrolled clinical trial. Private floatation spa therapy centre. Fourteen patients with chronic osteoarthritis of the weight-bearing joints, of whom four dropped out. Six weekly sessions of floatation spa therapy. SF36, AIMS2 and MYMOP quality-of-life questionnaires. All patients improved. Differences between baseline and discharge scores showed statistically significant improvement for MYMOP, but not AIMS2 or SF-36. Controlled trials of floatation spa therapy for patients with osteoarthritis are warranted.

  1. Phenotypical analysis of the Lactobacillus rhamnosus GG fimbrial spaFED operon: surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis.

    Directory of Open Access Journals (Sweden)

    Johanna Rintahaka

    Full Text Available A noticeable genomic feature of many piliated Gram-positive bacterial species is the presence of more than one pilus-encoding operon. Paradigmatically, the gut-adapted Lactobacillus rhamnosus GG strain contains two different fimbrial operons in its genome. However, whereas one of these operons (called spaCBA is encoding for the functionally mucus-/collagen-binding SpaCBA pilus, for the other operon (called spaFED any native expression of the SpaFED-called pili is still the subject of some uncertainty. Irrespective of such considerations, we decided it would be of relevance or interest to decipher the gross structure of this pilus type, and as well assess its functional capabilities for cellular adhesion and immunostimulation. For this, and by following the approach we had used previously to explicate the immuno-properties of SpaCBA pili, we constructed nisin-inducible expression clones producing either wild-type or SpaF pilin-deleted surface-assembled L. rhamnosus GG SpaFED pili on Lactococcus lactis cells. Using these piliated lactococcal constructs, we found that the pilin-polymerized architecture of a recombinant-produced SpaFED pilus coincides with sequence-based functional predictions of the related pilins, and in fact is prototypical of those other sortase-dependent pilus-like structures thus far characterized for piliated Gram-positive bacteria. Moreover, we confirmed that among the different pilin subunits encompassing spaFED operon-encoded pili, the SpaF pilin is a main adhesion determinant, and when present in the assembled structure can mediate pilus binding to mucus, certain extracellular matrix proteins, and different gut epithelial cell lines. However, somewhat unexpectedly, when recombinant SpaFED pili are surface-attached, we found that they could not potentiate the existing lactococcal cell-induced immune responses so elicited from intestinal- and immune-related cells, but rather instead, they could dampen them. Accordingly, we

  2. Phenotypical analysis of the Lactobacillus rhamnosus GG fimbrial spaFED operon: surface expression and functional characterization of recombinant SpaFED pili in Lactococcus lactis.

    Science.gov (United States)

    Rintahaka, Johanna; Yu, Xia; Kant, Ravi; Palva, Airi; von Ossowski, Ingemar

    2014-01-01

    A noticeable genomic feature of many piliated Gram-positive bacterial species is the presence of more than one pilus-encoding operon. Paradigmatically, the gut-adapted Lactobacillus rhamnosus GG strain contains two different fimbrial operons in its genome. However, whereas one of these operons (called spaCBA) is encoding for the functionally mucus-/collagen-binding SpaCBA pilus, for the other operon (called spaFED) any native expression of the SpaFED-called pili is still the subject of some uncertainty. Irrespective of such considerations, we decided it would be of relevance or interest to decipher the gross structure of this pilus type, and as well assess its functional capabilities for cellular adhesion and immunostimulation. For this, and by following the approach we had used previously to explicate the immuno-properties of SpaCBA pili, we constructed nisin-inducible expression clones producing either wild-type or SpaF pilin-deleted surface-assembled L. rhamnosus GG SpaFED pili on Lactococcus lactis cells. Using these piliated lactococcal constructs, we found that the pilin-polymerized architecture of a recombinant-produced SpaFED pilus coincides with sequence-based functional predictions of the related pilins, and in fact is prototypical of those other sortase-dependent pilus-like structures thus far characterized for piliated Gram-positive bacteria. Moreover, we confirmed that among the different pilin subunits encompassing spaFED operon-encoded pili, the SpaF pilin is a main adhesion determinant, and when present in the assembled structure can mediate pilus binding to mucus, certain extracellular matrix proteins, and different gut epithelial cell lines. However, somewhat unexpectedly, when recombinant SpaFED pili are surface-attached, we found that they could not potentiate the existing lactococcal cell-induced immune responses so elicited from intestinal- and immune-related cells, but rather instead, they could dampen them. Accordingly, we have now provided

  3. Perceptual incongruence influences bistability and cortical activation

    NARCIS (Netherlands)

    Brouwer, G.J.; Tong, F.; Hagoort, P.; van Ee, R.

    2009-01-01

    We employed a parametric psychophysical design in combination with functional imaging to examine the influence of metric changes in perceptual incongruence on perceptual alternation rates and cortical responses. Subjects viewed a bistable stimulus defined by incongruent depth cues; bistability

  4. A online credit evaluation method based on AHP and SPA

    Science.gov (United States)

    Xu, Yingtao; Zhang, Ying

    2009-07-01

    Online credit evaluation is the foundation for the establishment of trust and for the management of risk between buyers and sellers in e-commerce. In this paper, a new credit evaluation method based on the analytic hierarchy process (AHP) and the set pair analysis (SPA) is presented to determine the credibility of the electronic commerce participants. It solves some of the drawbacks found in classical credit evaluation methods and broadens the scope of current approaches. Both qualitative and quantitative indicators are considered in the proposed method, then a overall credit score is achieved from the optimal perspective. In the end, a case analysis of China Garment Network is provided for illustrative purposes.

  5. Influence of Physical Activities to Science Performance

    Directory of Open Access Journals (Sweden)

    RS Wilson DR. Constantino

    2017-11-01

    Full Text Available This study explored the physical activities of fifth and sixth graders that projected correlations to science performance and how these physical activities may be utilized for classroom purposes in the context of science-related play activities. Descriptive survey correlational design directed the data collection and analysis of the physical activities of purposively selected 133 fifth and sixth graders. Primarily, the study used a researcher-developed and validated instrument (Physical Activity Questionnaire [PAQ], and standard instruments: Philippine National Physical Activity Guide (PNPAG and General Physical Activity Questionnaire (GPAQ. The latter classified the physical activities into five domains which directed the interpretation of the participants‟ responses. The Pearson-r Moment of Correlation described the level of correlation of the frequency of engagement to physical activities (limited to local and localized activities and the science grade of the respondents. Results show that each of the physical activity domains showed specific correlations to science performance of the respondents. For further research, enrichment of the relationship of the physical activities and the science performance may focus on possible moderating variables like economic status, and time allotment for physical activities.

  6. [The development of the medical information system for the improvement of the quality of work of the Crimean spa and health resorts].

    Science.gov (United States)

    Ezhov, V V; Grigor'ev, P E; Mizin, V I; Andriiashek, Iu I; Gol'dberg, D L; Olenchuk, A V

    2016-01-01

    The Crimea has the enormous potential for the health promotion activities. However, neither the profile of these activities nor the demand for the socio-medical services is clearly defined for the majority of the local spa and health resort facilities. The possibilities of modern information technology are not used in the full measure either. The objective of the present work was to elaborate the new medical information system and demonstrate its effectiveness. In addition, the article describes the main advantages of the system for the optimization of healthcare in the Crimean spa and health resort facilities. We reviewed and analyzed various literature publications, legal framework, standards, regulations, guidelines, and questionnaire survey data obtain at 50 spa and health resort facilities of the Crimea. The results of the assessment indicate the necessity of the systematic approach to the analysis of the quality of medical care and the process of its further development. Statistical and mathematical methods were used to elaborate the medical information system for the optimization of the activities of the Crimean spa and health resorts. The distinctive features of the proposed information system are modularity and the possibility of flexible adjustment to the conditions of individual settings, one-step data loading with the subsequent multiple application for the formulation of documents, automated filling of records in compliance with the medical standards, and taking into consideration the possible changes in or amendments to the form of the documents. The data obtained in the course of project implementation were used for the first time in the Republic of Crimea to design, substantiate, and recommend for the practical application the algorithm for the comprehensive estimation of the results of treatment of the patients based at the spa and health resort facilities with due regard for the specific regional conditions.

  7. 77 FR 35888 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Airplanes

    Science.gov (United States)

    2012-06-15

    ...., Washington, DC 20590, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For service.... Relevant Service Information PIAGGIO AERO INDUSTRIES S.p.A. has issued Service Bulletin No. 80- 0318, dated... Instructions of Piaggio Aero Industries S.p.A. Mandatory Service Bulletin No. 80-0318, revision 2, dated March...

  8. 'MRI-tis' in the early diagnosis of axial SpA: issues and limitations

    NARCIS (Netherlands)

    de Rycke, Leen; Maas, Mario; Tak, Paul P.; Baeten, Dominique

    2010-01-01

    Sacroiliitis on conventional radiography, a key diagnostic feature of axial spondyloarthritis (SpA), often appears only late in the disease course. With the introduction of potent biologic agents that may also be effective in early disease, diagnostic techniques that can identify SpA early in the

  9. Patient education and rehabilitation after hip arthroplasty in an Italian spa center: a pilot study on its feasibility

    Science.gov (United States)

    Musumeci, Alfredo; Pranovi, Giulia; Masiero, Stefano

    2018-05-01

    Nowadays, some spa centers are suitable for providing rehabilitative and preventive treatment in association with traditional spa therapy. This study aims to evaluate the feasibility and the effectiveness of an intensive rehabilitation program after hip arthroplasty in an Italian spa center. Early after total hip arthroplasty for severe osteoarthritis (≤ 10 days after the intervention), 12 consecutive patients (5 males and 7 females) aged between 50 and 85 years were enrolled for this study. All the patients performed a 2-week thermal multimodal rehabilitation program, which consisted of education and physical rehabilitative measures. Patients had 2-h and half/day session of land-based and hydrokinesitherapy (aquatic therapy) consisted in active and passive joint mobilization, respiratory and functional re-education exercises, gait and balance training, resistance exercise, and power training mainly for the upper limb associated to physical therapy modalities (electrotherapy and low-level laser therapy). An educational program was performed to both patients and families. Both before and after the rehabilitation treatment, patients underwent clinical evaluation, hip flexion/abduction range of motion, and Numeric Pain Rating Scale. Harris Hip Score (HHS) and SF-12 questionnaires (physical—PCS-12—and mental health component—MCS-12) were also administered. After the 2-week thermal spa treatment, hip flexion/abduction improved significantly (p < 0.05), but there was no statistically significant reduction in pain (p = 0.350). The HHS score improved significantly from 62.6 ± 12.8 to 82.15 ± 12.7 (p < 0.05), and the PCS-12 score from 36.37 ± 8.4 to 43.61 ± 8.95 (p < 0.05). There was no adverse event during spa treatment. After total hip arthroplasty, patients who underwent an intensive post-acute multimodal rehabilitation program showed an improvement in motor and functional recovery and a positive impact on quality of life. Therefore, we believe that the

  10. HOSPITALITY ENGLISH FOR SPA THERAPISTS IN BANYAN TREE HOTELS AND RESORTS

    Directory of Open Access Journals (Sweden)

    Ratnasari Nugraheni

    2018-04-01

    Full Text Available This study is a preliminary study of research and design for hospitality English for SPA therapist in Banyan Tree Hotels and Resorts at Bintan Island. The purpose of this study is to help the English teacher to provide a successful English training since a good English proficiency used in the hospitality industry is obliged, especially for an-international-five-star-hotel-brand. The nature of the study is qualitative using R&D approach. Since this is only a preliminary study, need analysis becomes the primary focus. The data were collected through interview and observation. The participants were people who are working in SPA department in Banyan Tree Bintan, such as SPA trainer, SPA therapist, and SPA manager.

  11. Spa therapy for elderly: a retrospective study of 239 older patients with osteoarthritis

    Science.gov (United States)

    Karagülle, Mine; Kardeş, Sinan; Dişçi, Rian; Gürdal, Hatice; Karagülle, Müfit Zeki

    2016-10-01

    Very few studies tested the effectiveness of spa therapy in older patients with osteoarthritis. Therefore, we aimed to evaluate the short-term effects of spa therapy in patients aged 65 years and older with generalized, knee, hip, and cervical and lumbar spine osteoarthritis. In an observational retrospective study design at the Medical Ecology and Hydroclimatology Department of Istanbul Medical Faculty, we analyzed the records of 239 patients aged over 65 years with the diagnosis of all types of osteoarthritis who were prescribed a spa therapy course in some spa resorts in Turkey between 7 March 2002 and 31 December 2012. They travelled to a spa resort where they stayed at a thermal spa hotel and followed the usual therapy packages for 2 weeks. Patients were assessed by an experienced physician within a week before the spa journey and within a week after the completion of the spa therapy. Compared with baseline in whole sample, statistically significant improvements were observed in pain (visual analog scale, VAS), patient and physician global assessments (VAS), Health Assessment Questionnaire disability index (HAQ-DI), Lequesne algofunctional index (LAFI) for knee, Western Ontario and McMaster Universities index (WOMAC), Waddell disability index (WDI), and Neck Pain and Disability Scale (NPAD). According to Outcome Measures in Rheumatology—Osteoarthritis Research Society International (OMERACT-OARSI) Set of Responder Criteria, responder rate were 63.8 % (51/80) in generalized, 52 % (13/25) in knee, 50 % (2/4) in hip, 66.7 % (8/12) in lumbar, and 100 % (6/6) in cervical osteoarthritis subgroups. Spa therapy improved pain and physical functional status in older patients with osteoarthritis, especially generalized osteoarthritis and multiple joint osteoarthritis with involvement of knee. This improvement was clinically important in majority of the patients. To confirm the results of this preliminary study, there is a need of a randomized controlled clinical study

  12. Does Aerobic Exercise Influence Intrinsic Brain Activity?

    DEFF Research Database (Denmark)

    Flodin, Pär; Jonasson, Lars S; Riklund, Katrin

    2017-01-01

    exercise group or an active control group. Both groups recieved supervised training, 3 days a week for 6 months. Multimodal brain imaging data was acquired before and after the intervention, including 10 min of resting state brain functional magnetic resonance imaging (rs-fMRI) and arterial spin labeling......Previous studies have indicated that aerobic exercise could reduce age related decline in cognition and brain functioning. Here we investigated the effects of aerobic exercise on intrinsic brain activity. Sixty sedentary healthy males and females (64-78 years) were randomized into either an aerobic...... group improved more. Contrary to our hypothesis, we did not observe any significant group by time interactions with regard to any measure of intrinsic activity. To further probe putative relationships between fitness and brain activity, we performed post hoc analyses disregarding group belongings...

  13. Willingness of patients with ankylosing spondylitis to pay for inpatient treatment is influenced by the treatment environment and expectations of improvement.

    Science.gov (United States)

    Boonen, A; Severens, J L; van Tubergen, A; Landewé, R; Bonsel, G; van der Heijde, D; van der Linden, Sj

    2005-11-01

    To assess the willingness to pay (WTP) for treatment in a spa resort of patients with ankylosing spondylitis (AS) and to assess if the experience of a spa influences the WTP. 120 patients participating in a randomised trial comparing 3 weeks' treatment in a spa resort in Austria or in the Netherlands with a control group completed a WTP questionnaire before and after spa treatment. Patients indicated on a payment card the maximal co-payment they wanted to contribute for three scenarios that included (a) two levels of improvement in pain and stiffness and (b) two treatment environments: a rehabilitation hospital and a spa resort. At baseline, patients wanted to contribute more for the same improvement after treatment in a spa resort compared with a rehabilitation hospital (ppay more when expected effects were higher (pexpected improvement. Experiencing treatment in a spa resort does not influence the co-payment.

  14. 75 FR 76038 - Zach System Corporation a Subdivision of Zambon Company, SPA Including On-Site Leased Workers of...

    Science.gov (United States)

    2010-12-07

    ... Subdivision of Zambon Company, SPA Including On-Site Leased Workers of Turner Industries and Go Johnson, La..., including on-site leased workers from Turner Industries and Go Johnson, La Porte, Texas. The Department's... investigation revealed that Zach System Corporation is a subdivision of Zambon Company, SPA, not Zach System SPA...

  15. Comparing whole-genome sequencing with Sanger sequencing for spa typing of methicillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Bartels, Mette Damkjær; Petersen, Andreas; Worning, Peder; Nielsen, Jesper Boye; Larner-Svensson, Hanna; Johansen, Helle Krogh; Andersen, Leif Percival; Jarløv, Jens Otto; Boye, Kit; Larsen, Anders Rhod; Westh, Henrik

    2014-12-01

    spa typing of methicillin-resistant Staphylococcus aureus (MRSA) has traditionally been done by PCR amplification and Sanger sequencing of the spa repeat region. At Hvidovre Hospital, Denmark, whole-genome sequencing (WGS) of all MRSA isolates has been performed routinely since January 2013, and an in-house analysis pipeline determines the spa types. Due to national surveillance, all MRSA isolates are sent to Statens Serum Institut, where the spa type is determined by PCR and Sanger sequencing. The purpose of this study was to evaluate the reliability of the spa types obtained by 150-bp paired-end Illumina WGS. MRSA isolates from new MRSA patients in 2013 (n = 699) in the capital region of Denmark were included. We found a 97% agreement between spa types obtained by the two methods. All isolates achieved a spa type by both methods. Nineteen isolates differed in spa types by the two methods, in most cases due to the lack of 24-bp repeats in the whole-genome-sequenced isolates. These related but incorrect spa types should have no consequence in outbreak investigations, since all epidemiologically linked isolates, regardless of spa type, will be included in the single nucleotide polymorphism (SNP) analysis. This will reveal the close relatedness of the spa types. In conclusion, our data show that WGS is a reliable method to determine the spa type of MRSA. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  16. College Student Environmental Activism: How Experiences and Identities Influence Environmental Activism Approaches

    Science.gov (United States)

    King, Laura A. H.

    2016-01-01

    College student environmental activism is one way students civically engage in addressing social issues. This study explores the environmental activism of twelve college students and how their experiences outside of college and in college influenced their activism. In addition, how students' identities influenced their approach to activism was…

  17. [The spa-health resort and touristic-recreational facilities of the region: the methodological aspects of their development].

    Science.gov (United States)

    Kirilina, V M; Kolesnikova, N V; Kolesnikov, N G

    2016-01-01

    The correction and optimization of the motor activity of the patients are currently the main priorities of all rehabilitative and recreational activities based at the spa and health resort facilities. The forms of such activities include walking tours and excursion trips. In other words, the excursion potential is one of the very important attributes of the recreational recourses. Under the current conditions characterized by the rapid socio-economic changes, the studies concerning the structural and functional transformation of spa and health resorts, recreational and tourist facilities acquire special importance, both from the humanitarian and economic points of view. The results of these studies may greatly contribute to the organization and the further development of rehabilitative and recreational activities based at the spa and health resort facilities, recreational and tourist centers taking into consideration their evolution. The objective of the present article is to analyze the structure and functions of the recreation and tourist centres as well as the modes of their cooperation with the spa and health resort facilities. In other words, these structures and their functions are both the object and the subject of the present study. The methodology of the study is based on the logical analysis of the development of the recreational and tourist systems in the framework of the evolutionary approach. (1) the notions of «tourist destination» and «recreation» have been substantiated; (2) the results of the studies carried out at the Institute of Physical Culture, Sports and Tourism and the Petrozavodsk State University have been used to elaborate the affiliate international Master Degree program «Project management in the tourism industry». The main emphasis in this program is placed on the necessity and methods of the improvement of recreational activities and more efficacious utilization of the climatic factors and the health resort infrastructure as

  18. Role of spontaneous physical activity in prediction of susceptibility to activity based anorexia in male and female rats.

    Science.gov (United States)

    Perez-Leighton, Claudio E; Grace, Martha; Billington, Charles J; Kotz, Catherine M

    2014-08-01

    Anorexia nervosa (AN) is a chronic eating disorder affecting females and males, defined by body weight loss, higher physical activity levels and restricted food intake. Currently, the commonalities and differences between genders in etiology of AN are not well understood. Animal models of AN, such as activity-based anorexia (ABA), can be helpful in identifying factors determining individual susceptibility to AN. In ABA, rodents are given an access to a running wheel while food restricted, resulting in paradoxical increased physical activity levels and weight loss. Recent studies suggest that different behavioral traits, including voluntary exercise, can predict individual weight loss in ABA. A higher inherent drive for movement may promote development and severity of AN, but this hypothesis remains untested. In rodents and humans, drive for movement is defined as spontaneous physical activity (SPA), which is time spent in low-intensity, non-volitional movements. In this paper, we show that a profile of body weight history and behavioral traits, including SPA, can predict individual weight loss caused by ABA in male and female rats with high accuracy. Analysis of the influence of SPA on ABA susceptibility in males and females rats suggests that either high or low levels of SPA increase the probability of high weight loss in ABA, but with larger effects in males compared to females. These results suggest that the same behavioral profile can identify individuals at-risk of AN for both male and female populations and that SPA has predictive value for susceptibility to AN. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. INFLUENCE OF SELECTED PHARMACEUTICALS ON ACTIVATED SLUDGE DEHYDROGENASE ACTIVITY

    Directory of Open Access Journals (Sweden)

    Agnieszka Tomska

    2016-06-01

    The aim of this work was to evaluate the effect of selected antibiotics - sulfanilamide and erythromycin on activated sludge dehydrogenase activity with use of trifenyltetrazolinum chloride (TTC test. Dehydrogenases activity is an indicator of biochemical activity of microorganisms present in activated sludge or the ability to degrade organic compounds in waste water. TTC test is particularly useful for the regularity of the course of treatment, in which the presence of inhibitors of biochemical reactions and toxic compounds are present. It was observed that the dehydrogenase activity decreases with the increase of a antibiotics concentration. The lowest value of the dehydrogenase activity equal to 32.4 μmol TF / gMLSS obtained at sulfanilamide concentration 150mg / l. For this sample, an inhibition of dehydrogenase activity was 31%.

  20. Active Play: Exploring the Influences on Children's School Playground Activities

    Science.gov (United States)

    Hyndman, Brendon; Benson, Amanda; Telford, Amanda

    2016-01-01

    Because children spend so much of their time in schools, their playgrounds offer a good setting for promoting active play in young lives. Teachers, instead of considering active play a taxing demand on their busy day, have begun to develop an informal curriculum for it. The authors review the research on children's active play and explores its…

  1. COMPETITIVENESS THROUGH SUSTAINABILITY AND FINANCIAL EFFICIENCY OF SPA TOURIST DESTINATIONS

    Directory of Open Access Journals (Sweden)

    Anis Cecilia

    2010-12-01

    Full Text Available In the specific literature, success may be achieved by two important attributes: competitiveness and sustainability. Competitive advantage represents an essential criterion for surviving on the tourist market and defines the ability of one destination to use these resources effectively and in the long term. The paper work continue a study begun last year by the same authors about tourist perception of attractiveness of the two tourist SPA destinations (Buziaş and Băile Felix on a different market segment (18-35 years old people. This time, we undertake an analysis on SC Turism Felix SA in order to determine and underline the tourist competitiveness through sustainability and financial efficiency (tourism performance indicators evolution, market share, turnover, investment volume, financial returns and costs.

  2. [INDENA SPA company's patent portfolio of Ginkgo biloba preparation].

    Science.gov (United States)

    Wang, Nan; Guo, Kai; Cheng, Xin-min; Liu, Wei

    2015-10-01

    INDENA SPA Company in Italy is a multi-national company that produces and sells plant extracts. Based on its own re- search advantages in the field of Ginkgo biloba preparation, the company protects its own products market effectively through building patent portfolio around the patents of its opponent. Based on the multi-angle analysis for patent portfolio of G. biloba preparation from the aspects of application time, legal status, technical development route, and patent portfolio layout, this article provides technical reference on research and development of G. biloba preparation, and the author suggest that Chinese applicants learn techniques and layout experiences of other patents fully to enhance the level of research and patent protection level.

  3. AIR SEBAGAI ALAT PENGENDALI IKLIM MIKRO DALAM BANGUNAN Studi Kasus : Taman Sari Royal Heritage Spa, Hotel Sheraton Mustika Yogyakarta

    Directory of Open Access Journals (Sweden)

    Dyah Hendrawati

    2016-07-01

    Full Text Available Indonesia is a country with wet tropical climate has constraints in obtaining thermal comfort because of the high air temperature, high air humidity and lower air speed. Modification of the microclimate might be conducted by increasing the cooling effect in a passive manner. Water can be used as one of control strategy thermal to build the microclimate or to site. Water also played an important role in lowering temperature and raise humidity in a room in building.Taman Sari Royal Heritage Spa, which is located in Yogyakarta,is one of building that implementing water as thermal control by making pool in door. This research aims to understand the influence of water in controlling the micro climate and the anything influence it .This research uses the quantitative methods by conducting observation and measuring temperature and humidity directly to the research objects. Secondary data is needed in this research. There was also literature review on the stuff that supports research, and a literature study was also conducted. The research and analysis on the results shows that 1 .The room in Tamansari royal heritage spa still in comfort zone in thermal .2 .The volume of water affects temperatures and humidity room 3 .Distance is a significant factor.

  4. Elementi koji diferenciraju ugovor o spašavanju od ugovora o tegljenju : (prikaz presude

    Directory of Open Access Journals (Sweden)

    Vesna Skorupan Wolff

    2016-07-01

    Full Text Available Brod kojem su se zaustavili porivni strojevi, a uslijed toga vjetar i morska struja nosili su ga prema obali, zatražio je uslugu tegljenja. Između stranaka je sporno radi li se u konkretnom slučaju o ugovoru o tegljenju ili ugovoru o spašavanju. Spašavanje je svaka djelatnosti kojoj je svrha spašavanje osoba, brodova i stvari s tih brodova. Bitan element pojma spašavanja jest da se osoba, odnosno stvar koja se spašava nalazi u opasnosti (opasnost po život osoba, odnosno propast stvari. Pod spašavanjem se podrazumijeva i pružanje pomoći. Ako je pomoć pružena tegljenjem, to ne znači da se radi o pravnom poslu tegljenja. U konkretnom slučaju u pitanju nije bio komercijalni posao tegljenja već posao spašavanja.

  5. Influence Of Dilution Factor For Activity Measurement Of 60CO

    International Nuclear Information System (INIS)

    Hermawan-Candra; Nazaroh; Ermi-Juita

    2003-01-01

    Influence of dilution factor for activity measurement of 60 Co has been studied. The aim of this research is to determine influence between activity measurement result of 60 Co before and after diluted. Measurement were done by using ionization chamber detectors system and gamma spectrometry system with NaI(TI) detector. Discrepancy within three ionization chambers measurements were 0.2% - 2.1% and NaI(Tl) were 3.5% - 6%. (author)

  6. Parental Influence on Physical Activity of Children with Disabilities

    Science.gov (United States)

    Siebert, Erin A.; Hamm, Jessica; Yun, Joonkoo

    2017-01-01

    The purpose of this study was to identify parental influences on physical activity behaviours of children with disabilities. One hundred and forty-eight parents of children with disabilities responded to a survey about factors related to parent and child physical activity, parental support and belief in their child's abilities regarding physical…

  7. The impact of spa treatment on quality of life of elderly people

    Directory of Open Access Journals (Sweden)

    Marta Wardeńska

    2017-02-01

    Full Text Available The aim of this study was to assess the impact of the spa treatment on the quality of life of the older people. The study included 18 women and 22 men over 60 years of age. Method used was diagnostic survey - a questionnaire containing closed and open questions, on the subjective assessment of their own quality of life, as well as spa treatment and its impact on health and well-being. This study lead to a conclusion that due the spa treatment, the quality of life of patients over 60 ages expressed their subjective assessment improves. This confirms the hypothesis that older people using spa treatment are characterized by a significantly higher level of quality of life.

  8. Kaks kuud Kalev SPA-s / kommenteerinud Julia Kurbat, Natalia Nazarenko-Kiivikas, Margit Lipstuhl

    Index Scriptorium Estoniae

    2012-01-01

    Kahe spordiharrastaja Kaur Sau ja Kadri Sõggeli seatud eesmärkidest 2012. aastal ja kehalisest arengust treenides kaks kuud mõnes Tallinna spordiklubis. Treeningutest Kalev Spa Hotel & Water Park'i nimekandvas spordi- ja vabaajakeskuses

  9. Surfactant protein A (SP-A) inhibits agglomeration and macrophage uptake of toxic amine modified nanoparticles.

    Science.gov (United States)

    McKenzie, Zofi; Kendall, Michaela; Mackay, Rose-Marie; Whitwell, Harry; Elgy, Christine; Ding, Ping; Mahajan, Sumeet; Morgan, Cliff; Griffiths, Mark; Clark, Howard; Madsen, Jens

    2015-01-01

    The lung provides the main route for nanomaterial exposure. Surfactant protein A (SP-A) is an important respiratory innate immune molecule with the ability to bind or opsonise pathogens to enhance phagocytic removal from the airways. We hypothesised that SP-A, like surfactant protein D, may interact with inhaled nanoparticulates, and that this interaction will be affected by nanoparticle (NP) surface characteristics. In this study, we characterise the interaction of SP-A with unmodified (U-PS) and amine-modified (A-PS) polystyrene particles of varying size and zeta potential using dynamic light scatter analysis. SP-A associated with both 100 nm U-PS and A-PS in a calcium-independent manner. SP-A induced significant calcium-dependent agglomeration of 100 nm U-PS NPs but resulted in calcium-independent inhibition of A-PS self agglomeration. SP-A enhanced uptake of 100 nm U-PS into macrophage-like RAW264.7 cells in a dose-dependent manner but in contrast inhibited A-PS uptake. Reduced association of A-PS particles in RAW264.7 cells following pre-incubation of SP-A was also observed with coherent anti-Stokes Raman spectroscopy. Consistent with these findings, alveolar macrophages (AMs) from SP-A(-/-) mice were more efficient at uptake of 100 nm A-PS compared with wild type C57Bl/6 macrophages. No difference in uptake was observed with 500 nm U-PS or A-PS particles. Pre-incubation with SP-A resulted in a significant decrease in uptake of 100 nm A-PS in macrophages isolated from both groups of mice. In contrast, increased uptake by AMs of U-PS was observed after pre-incubation with SP-A. Thus we have demonstrated that SP-A promotes uptake of non-toxic U-PS particles but inhibits the clearance of potentially toxic A-PS particles by blocking uptake into macrophages.

  10. Effect of a steam foot spa on geriatric inpatients with cognitive impairment: a pilot study

    OpenAIRE

    Koike Y; Kondo H; Kondo S; Takagi M; Kano Y

    2013-01-01

    Yoshihisa Koike,1 Hideki Kondo,2 Satoshi Kondo,1 Masayuki Takagi,1 Yoshio Kano31Department of Occupational Therapy, Prefectural University of Hiroshima, Mihara, Japan; 2Yoshiigawa Hospital, Okayama, Japan; 3Department of Occupational Therapy, Kibi International University, Takahashi, JapanPurpose: To investigate whether a steam foot spa improves cognitive impairment in geriatric inpatients.Methods: Geriatric inpatients with cognitive impairment were given a steam foot spa treatment at 42&...

  11. [Balneotherapy and spa therapy of rheumatic diseases in Turkey: a systematic review].

    Science.gov (United States)

    Karagülle, M Z; Karagülle, M

    2004-02-01

    Turkey has a lot of thermal and mineral springs and is looking back on a still vivid tradition of spa therapy and balneotherapy, applied especially for the treatment of rheumatic diseases. This tradition is predominantly empiric and intuitive, however, it has assumed some important aspects of modern balneotherapeutic methods as well. This article is aimed at presenting the characteristics of traditional and modern balneological and spa therapy forms in Turkey. The studies which have been conducted between 1990 and 2000 in different spas in Turkey on the efficacy and effectiveness of spa therapy and balneotherapy for rheumatic diseases have been searched and analyzed independent of their design. A descriptive evaluation of the studies was carried out. A total of 15 published studies have been found and analyzed. The investigations have been carried out in 8 different spa resorts in Turkey. In these studies the effectiveness and efficacy of different balneological and spa therapies on a variety of rheumatic diseases (from osteoarthritis to fibromyalgia and from rheumatoid arthritis to low back pain) could be shown. Nearly all studied balneotherapeutic modalities were applied as bathing cures. Only in one study peloid therapy was applied. Balneotherapeutic therapy was applied in a modern and traditional way, and both open and stationary spa therapy forms were used at the same time. The review has shown the effectiveness of the investigated spa therapy and balneotherapy forms. It could be concluded that nearly all forms of spa therapy and balneotherapy used for the treatment of rheumatic diseases in Turkey are effective. A definitive conclusion, however, is not possible because of the heterogeneity of the study designs, methodological flaws, and the publication bias. In future good quality randomized controlled trials are needed. Copyright 2004 S. Karger GmbH, Freiburg

  12. Spa therapy in the treatment of knee osteoarthritis: a large randomised multicentre trial

    Science.gov (United States)

    Forestier, R; Desfour, H; Tessier, J-M; Françon, A; Foote, A M; Genty, C; Rolland, C; Roques, C-F; Bosson, J-L

    2010-01-01

    Objective To determine whether spa therapy, plus home exercises and usual medical treatment provides any benefit over exercises and usual treatment, in the management of knee osteoarthritis. Methods Large multicentre randomised prospective clinical trial of patients with knee osteoarthritis according to the American College of Rheumatology criteria, attending French spa resorts as outpatients between June 2006 and April 2007. Zelen randomisation was used so patients were ignorant of the other group and spa personnel were not told which patients were participating. The main endpoint criteria were patient self-assessed. All patients continued usual treatments and performed daily standardised home exercises. The spa therapy group also received 18 days of spa therapy (massages, showers, mud and pool sessions). Main Endpoint The number of patients achieving minimal clinically important improvement (MCII) at 6 months, defined as ≥19.9 mm on the visual analogue pain scale and/or ≥9.1 points in a normalised Western Ontario and McMaster Universities osteoarthritis index function score and no knee surgery. Results The intention to treat analysis included 187 controls and 195 spa therapy patients. At 6 months, 99/195 (50.8%) spa group patients had MCII and 68/187 (36.4%) controls (χ2=8.05; df=1; p=0.005). However, no improvement in quality of life (Short Form 36) or patient acceptable symptom state was observed at 6 months. Conclusion For patients with knee osteoarthritis a 3-week course of spa therapy together with home exercises and usual pharmacological treatments offers benefit after 6 months compared with exercises and usual treatment alone, and is well tolerated. Trial registration number NCT00348777. PMID:19734131

  13. Hotel Online Marketing: The Bugibba Hotel, Radisson Blu Resort Malta, St. Julian's, Preluna Hotel & SPA

    OpenAIRE

    Dinh Quynh, Mai

    2013-01-01

    The thesis covers the study of online marketing theory, a very popular trend of marketing nowadays, especially Search Engine Optimization (SEO) and Google Adwords Campaign in the analyses of the online marketing practices of three hotels from different areas and standards in Malta, namely The Bugibba Hotel, Preluna Hotel & SPA and Radisson Blu Resort Malta, St. Julian’s. From the analyses, the thesis aims at suggesting Preluna Hotel & SPA optimal online marketing practices and answering t...

  14. Potentials for development of spa tourism in region of Cer Mountain: Western Serbia

    Directory of Open Access Journals (Sweden)

    Grčić Mirko

    2006-01-01

    Full Text Available Because of their particularities, thermal and mineral springs at the foothill of Cer Mountain deserve special analysis. This is the reason we wrote this article, aiming to take reader's attention to the touristic potentials of the spa zone of Cer Mountain and possibilities for its perspective development. From the medical and excursion-recreational tourism point of view, there is a possibility for combining the spa tourism with the complementary values of Cer Mountain.

  15. Romanian spa tourism: a communist paradigm in a post communist era

    OpenAIRE

    George Erdeli; Ana Irina Dincă; Aurel Gheorghilas; Camelia Surugiu

    2011-01-01

    Spa tourism is one of the oldest forms of tourism which continuously evolved in time as the leisure industry paradigm and the consumers’ behavior changed. Similar to other countries in Central and Eastern Europe, spa tourism is an old phenomenon in Romania which expanded to the dimensions of a well defined tourism industry during the mass tourism period which also corresponded to the communism epoch. Although severely affected by the major political and socio-economic changes which occurred a...

  16. Influence of friends on children's physical activity: a review.

    Science.gov (United States)

    Maturo, Claire C; Cunningham, Solveig A

    2013-07-01

    We examined evidence for friendship influences on children's physical activity (PA) through systematic searches of online databases in May 2012. We identified 106 studies (25 qualitative) published in English since 2000 that analyzed indicators of friendship influences (e.g., communication about PA, friends' PA, and PA with friends) among persons younger than 19 years. Children's PA was positively associated with encouragement from friends (43 of 55 studies indicating a positive relationship), friends' own PA (30/35), and engagement with friends in PA (9/10). These findings are consistent with friends influencing PA, but most studies did not isolate influence from other factors that could explain similarity. Understanding friendship influences in childhood can facilitate the promotion of lifelong healthy habits. PA with friends should be considered in health promotion programs.

  17. Spa Treatment (Balneotherapy) for Fibromyalgia—A Qualitative-Narrative Review and a Historical Perspective

    Science.gov (United States)

    Ablin, Jacob N.; Buskila, Dan

    2013-01-01

    Aim. To perform a narrative review of spa therapy for management of the fibromyalgia syndrome (FMS), evaluating this traditional time-honored form of therapy in a historical perspective. Methods. Medline was searched using the terms “Spa therapy,” “Balneotherapy,” and “Fibromyalgia” between 1990 (year of ACR fibromyalgia criteria publication) and April 2013. The Cochrane database was also searched. Publications relating to the implementation of spa therapy and related practices over the centuries were identified through references, searched, and reviewed. Results. Reports of balneotherapy were described from diverse locations throughout Europe and Asia, and various forms of water-related therapy have been incorporated for many musculoskeletal indications. In the management of FMS, spa therapy has generally been shown to be well accepted and moderately effective for symptom reduction. Conclusion. While achieving high-quality evidence-based conclusions is difficult for complex natural therapies such as spa therapy, the existing evidence indicates a positive effect in management of FMS. In view of the long history of this modality in the management of rheumatic pain as well as the inherent difficulties related to pharmacological treatment, the role of spa therapy should currently be recognized as part of a therapeutic program for FMS. PMID:23983795

  18. Spa Treatment (Balneotherapy for Fibromyalgia—A Qualitative-Narrative Review and a Historical Perspective

    Directory of Open Access Journals (Sweden)

    Jacob N. Ablin

    2013-01-01

    Full Text Available Aim. To perform a narrative review of spa therapy for management of the fibromyalgia syndrome (FMS, evaluating this traditional time-honored form of therapy in a historical perspective. Methods. Medline was searched using the terms “Spa therapy,” “Balneotherapy,” and “Fibromyalgia” between 1990 (year of ACR fibromyalgia criteria publication and April 2013. The Cochrane database was also searched. Publications relating to the implementation of spa therapy and related practices over the centuries were identified through references, searched, and reviewed. Results. Reports of balneotherapy were described from diverse locations throughout Europe and Asia, and various forms of water-related therapy have been incorporated for many musculoskeletal indications. In the management of FMS, spa therapy has generally been shown to be well accepted and moderately effective for symptom reduction. Conclusion. While achieving high-quality evidence-based conclusions is difficult for complex natural therapies such as spa therapy, the existing evidence indicates a positive effect in management of FMS. In view of the long history of this modality in the management of rheumatic pain as well as the inherent difficulties related to pharmacological treatment, the role of spa therapy should currently be recognized as part of a therapeutic program for FMS.

  19. spa typing and antimicrobial resistance of Staphylococcus aureus from healthy humans, pigs and dogs in Tanzania.

    Science.gov (United States)

    Katakweba, Abdul Sekemani; Muhairwa, Amandus Pachificus; Espinosa-Gongora, Carmen; Guardabassi, Luca; Mtambo, Madundo M A; Olsen, John Elmerdahl

    2016-02-28

    Staphylococcus aureus is an opportunistic pathogen causing infections in humans and animals. Here we report for the first time the prevalence of nasal carriage, spa typing and antimicrobial resistance of S. aureus in a Tanzanian livestock community. Nasal swabs were taken from 100 humans, 100 pigs and 100 dogs in Morogoro Municipal. Each swab was enriched in Mueller Hinton broth with 6.5% NaCl and subcultured on chromogenic agar for S. aureus detection. Presumptive S. aureus colonies were confirmed to the species level by nuc PCR and analysed by spa typing. Antimicrobial susceptibility patterns were determined by disc diffusion method. S. aureus was isolated from 22% of humans, 4% of pigs and 11% of dogs. A total of 21 spa types were identified: 13, 7 and 1 in human, dogs, and pigs, respectively. Three spa types (t314, t223 and t084) were shared between humans and dogs. A novel spa type (t10779) was identified in an isolate recovered from a colonized human. Antimicrobials tested revealed resistance to ampicillin in all isolates, moderate resistances to other antimicrobials with tetracycline resistance being the most frequent. S. aureus carrier frequencies in dogs and humans were within the expected range and low in pigs. The S. aureus spa types circulating in the community were generally not shared by different hosts and majority of types belonged to known clones. Besides ampicillin resistance, moderate levels of antimicrobial resistance were observed irrespective of the host species from which the strains were isolated.

  20. Environmental influences on food choice, physical activity and energy balance.

    Science.gov (United States)

    Popkin, Barry M; Duffey, Kiyah; Gordon-Larsen, Penny

    2005-12-15

    In this paper, the environment is defined as the macro- and community-level factors, including physical, legal and policy factors, that influence household and individual decisions. Thus, environment is conceived as the external context in which household and individual decisions are made. This paper reviews the literature on the ways the environment affects diet, physical activity, and obesity. Other key environmental factors discussed include economic, legal, and policy factors. Behind the major changes in diet and physical activity in the US and globally lie large shifts in food production, processing, and distribution systems as well as food shopping and eating options, resulting in the increase in availability of energy-dense foods. Similarly, the ways we move at home, work, leisure, and travel have shifted markedly, resulting in substantial reductions in energy expenditure. Many small area studies have linked environmental shifts with diet and activity changes. This paper begins with a review of environmental influences on diet and physical activity, and includes the discussion of two case studies on environmental influences on physical activity in a nationally representative sample of US adolescents. The case studies illustrate the important role of physical activity resources and the inequitable distribution of such activity-related facilities and resources, with high minority, low educated populations at strong disadvantage. Further, the research shows a significant association of such facilities with individual-level health behavior. The inequity in environmental supports for physical activity may underlie health disparities in the US population.

  1. Spa-Wellness Center as Part of the Hotel Facility

    Directory of Open Access Journals (Sweden)

    Milica Rančić

    2013-04-01

    Full Text Available Over the last decades “wellness spa” industry has experienced a boom around the world. The word “Wellness” has been formed by merging two words: “Well Being” + “fitness”, and appeared in the thirties of the last century in the United States. The primary objective of this movement is an ancient philosophy, according to which there ́s no fulfilled life without the assent of the physical and mental, also physical and spiritual. Hotel guests, today more than ever, want higher quality offer for their money. This means that wellness is today a very important criterion by which customers select hotels. For this reason it is necessary to pay great attention to the planning, design and construction of this part of the hotel facility. The subject of this paper is wellness and spa centers as part of the hotel facility. The task is to investigate and analyze elements of this space, to determine spatial areas of wellness center, as well as their relationships and spatial organization, in order to reach the goal - getting useful guidelines for planning quality wellness center. To all of this could be achieved, we must first go back to distant history where dating back the beginnings of wellness.

  2. A checklist to assess the quality of reports on spa therapy and balneotherapy trials was developed using the Delphi consensus method: the SPAC checklist.

    Science.gov (United States)

    Kamioka, Hiroharu; Kawamura, Yoichi; Tsutani, Kiichiro; Maeda, Masaharu; Hayasaka, Shinya; Okuizum, Hiroyasu; Okada, Shinpei; Honda, Takuya; Iijima, Yuichi

    2013-08-01

    The purpose of this study was to develop a checklist of items that describes and measures the quality of reports of interventional trials assessing spa therapy. The Delphi consensus method was used to select the number of items in the checklist. A total of eight individuals participated, including an epidemiologist, a clinical research methodologist, clinical researchers, a medical journalist, and a health fitness programmer. Participants ranked on a 9-point Likert scale whether an item should be included in the checklist. Three rounds of the Delphi method were conducted to achieve consensus. The final checklist contained 19 items, with items related to title, place of implementation (specificity of spa), care provider influence, and additional measures to minimize the potential bias from withdrawals, loss to follow-up, and low treatment adherence. This checklist is simple and quick to complete, and should help clinicians and researchers critically appraise the medical and healthcare literature, reviewers assess the quality of reports included in systematic reviews, and researchers plan interventional trials of spa therapy. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Co-brand strategy of evaluation of visual images in furniture design: Jimmy S.P.A. and STRAUSS as examples

    Science.gov (United States)

    Chen, Tien-Li; Pan, Fang-Ming; Tsai, Jen-Hui

    2013-03-01

    This study aimed to investigate the correlation of the image associated by the design Co-Brand (Jimmy S.P.A. and STRAUSS) and the impression perceived by subject of viewers. Visual images were used to examine the merit of the evaluation. The best result is provided using an object as an appropriate evaluation method. There are a lot of factors which influence to evaluation of a design. This study is limited to distinguish the appearance from Jimmy's picture books transform furniture and so on. Co-Brand of Jimmy S.P.A. and STRAUSS is not easy because there are not from the same cultural, and industry background and applying different marketing strategy, it is a way to combine the two brands by designing, used questionnaire of SD (Semantic differential evaluation) evaluation method to test out the perception of viewers, the objective of this study is to investigate and appraised the Co-Brands use by of the image in furniture from patrons. SD evaluation result showed, if design cannot understand the perception image of Jimmy S.P.A and STRAUSS with viewers mind, furniture design also can't transmit feeling with design.

  4. Determination of uranium and polonium in Spa rus aura ta by alpha spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Luna P, M.; Renteria, M.; Montero C, M. E. [Centro de Investigacion en Materiales Avanzados, S. C., Miguel de Cervantes No. 120, Complejo Industrial Chihuahua, 31109 Chihuahua (Mexico); Manjon C, G.; Diaz, I., E-mail: elena.montero@cimav.edu.mx [Universidad de Sevilla, Escuela Tecnica Superior de Arquitectura, Departamento de Fisica Aplicada II, San Fernando No. 4, 41004 Sevilla (Spain)

    2012-06-15

    The aim of this study was optimizing conditions for the specific activities determination of some uranium-series radionuclides present in Spa rus aura ta by alpha spectrometry. Determinations of specific activities were conducted varying the type of digestion: acid attack on hot plate, controlled microwave digestion and acid attack after calcination of the sample. The latter procedure was applied only to the case of uranium isotopes determination. The variation in the isotope extraction method consisted of applying the techniques of liquid-liquid extracting using Tributyl phosphate or chromatographic UTEVA resin. Results depending on the type of treatment given to the samples were compared based on obtained chemical yields. The results reveal a higher bioaccumulation of polonium in the liver sample, with activities of 0.809, 2.495 and 2.439 Bq kg{sup -1} fresh wt compared with the fillet. The best chemical yields of polonium were close to 60% for samples that were digested by microwave. In the case of uranium the best chemical yields, close to 80% for fillet, were obtained with a previous calcination of the sample and using the UTEVA resin. (Author)

  5. Determination of uranium and polonium in Spa rus aura ta by alpha spectrometry

    International Nuclear Information System (INIS)

    Luna P, M.; Renteria, M.; Montero C, M. E.; Manjon C, G.; Diaz, I.

    2012-01-01

    The aim of this study was optimizing conditions for the specific activities determination of some uranium-series radionuclides present in Spa rus aura ta by alpha spectrometry. Determinations of specific activities were conducted varying the type of digestion: acid attack on hot plate, controlled microwave digestion and acid attack after calcination of the sample. The latter procedure was applied only to the case of uranium isotopes determination. The variation in the isotope extraction method consisted of applying the techniques of liquid-liquid extracting using Tributyl phosphate or chromatographic UTEVA resin. Results depending on the type of treatment given to the samples were compared based on obtained chemical yields. The results reveal a higher bioaccumulation of polonium in the liver sample, with activities of 0.809, 2.495 and 2.439 Bq kg -1 fresh wt compared with the fillet. The best chemical yields of polonium were close to 60% for samples that were digested by microwave. In the case of uranium the best chemical yields, close to 80% for fillet, were obtained with a previous calcination of the sample and using the UTEVA resin. (Author)

  6. Lessons from the SPA European performance assessment exercise for spent fuel disposal in granite

    International Nuclear Information System (INIS)

    Baudoin, P.; Besnus, F.; Gay, D.; Serres, C.

    2000-01-01

    The SPA project, addressing performance assessment of spent fuel disposal, is a direct continuation of the efforts made by the European Community since 1982 to build a common understanding of the methods applicable to performance assessment of a deep geological disposal. It enabled to draw preliminary conclusions on the respective importance of the radionuclides present in the different types of waste, on the influence of some of the main assumptions used in the modelling and helped to specify the expectable role of disposal system components. From 1996 to 1999, six national research institutions in six member countries of EU (Spain, Germany, France, The Netherlands, Belgium and Finland) were involved in this project devoted to the case of spent fuel. This paper only addresses the assessments made by IPSN (France) for the granite site in the case of the normal evolution scenario. According to the results obtained, the maximum effective dose is in a first time mainly caused by two fission products ( 129 I and 79 Se). Then, radionuclides from radioactive decay chains ( 226 Ra , 230 Th and 229 Th) progressively become the main contributors. (author)

  7. The role of open-air inhalatoria in the air quality improvement in spa towns.

    Science.gov (United States)

    Burkowska-But, Aleksandra; Kalwasińska, Agnieszka; Brzezinska, Maria Swiontek

    2014-08-01

    The present study was aimed at evaluating microbiological contamination of air in Ciechocinek and Inowrocław - Polish lowland spa towns. Additionally, the impact of open-air inhalatoria on the quality of air was evaluated. Air samples were collected seasonally in the urban areas, in the recreation areas and in the vicinity of inhalatoria in both towns using impaction. The numbers of mesophilic bacteria, staphylococci, hemolytic bacteria and actinomycetes were determined on media according to the Polish Standard PN-86/Z-04111/02. The number of moulds was determined on media according to the Polish Standard PN-86/Z-04111/03. While the highest numbers of microorganisms were noted at the sites located in the urban areas, the lowest numbers were noted in the vicinity of the open-air inhalatoria. In all the investigated air samples the values of bioaerosol concentrations were below the recommended TLVs (≤ 5000 CFU×m(-3) for both bacteria and fungi in outdoor environments). Location of the sampling site was invariably a decisive factor in determining the number of microorganisms in the air. The aerosol which is formed in the open-air inhalatoria has a positive influence on microbiological air quality. Owing to a unique microclimate and low air contamination, Ciechocinek and Inowrocław comply with all necessary requirements set for health resorts specializing in treating upper respiratory tract infections.

  8. [Study on influence between activated carbon property and immobilized biological activated carbon purification effect].

    Science.gov (United States)

    Wang, Guang-zhi; Li, Wei-guang; He, Wen-jie; Han, Hong-da; Ding, Chi; Ma, Xiao-na; Qu, Yan-ming

    2006-10-01

    By means of immobilizing five kinds of activated carbon, we studied the influence between the chief activated carbon property items and immobilized bioactivated carbon (IBAC) purification effect with the correlation analysis. The result shows that the activated carbon property items which the correlation coefficient is up 0.7 include molasses, abrasion number, hardness, tannin, uniform coefficient, mean particle diameter and effective particle diameter; the activated carbon property items which the correlation coefficient is up 0.5 include pH, iodine, butane and tetrachloride. In succession, the partial correlation analysis shows that activated carbon property items mostly influencing on IBAC purification effect include molasses, hardness, abrasion number, uniform coefficient, mean particle diameter and effective particle diameter. The causation of these property items bringing influence on IBAC purification is that the activated carbon holes distribution (representative activated carbon property item is molasses) provides inhabitable location and adjust food for the dominance bacteria; the mechanical resist-crash property of activated carbon (representative activated carbon property items: abrasion number and hardness) have influence on the stability of biofilm; and the particle diameter size and distribution of activated carbon (representative activated carbon property items: uniform coefficient, mean particle diameter and effective particle diameter) can directly affect the force of water in IBAC filter bed, which brings influence on the dominance bacteria immobilizing on activated carbon.

  9. Adolescent Involvement in Extracurricular Activities: Influences on Leadership Skills

    Science.gov (United States)

    Hancock, Donna; Dyk, Patricia Hyjer; Jones, Kenneth

    2012-01-01

    Study examined adolescents' participation in sports, school, and community extracurricular activities to assess the influence of different involvement roles and adult support on leadership skills. The study found that males and females who perceived their adult support more positively had more positive perceptions of their leadership skills.…

  10. Influences on seizure activity in pregnant women with epilepsy

    DEFF Research Database (Denmark)

    Sabers, Anne

    2009-01-01

    This study evaluated whether referral to a specialized epilepsy clinic prior to pregnancy influences seizure activity during pregnancy. In addition, folic acid supplementation prior to pregnancy as a marker of intent to conceive was used to evaluate whether the use of folic acid at the time of co...

  11. Treatment with mPEG-SPA improves the survival of corneal grafts in rats by immune camouflage.

    Science.gov (United States)

    Wang, Shuangyong; Li, Liangliang; Liu, Ying; Li, Chaoyang; Zhang, Min; Wang, Bowen; Huang, Zheqian; Gao, Xinbo; Wang, Zhichong

    2015-03-01

    We investigated the immune camouflage effects of methoxy polyethylene glycol succinimidyl propionate (mPEG-SPA) on corneal antigens and explored a novel approach for reducing corneal antigenicity, thereby decreasing corneal graft rejection. Importantly, this approach did not alter normal local immunity. Corneal grafts were treated with mPEG-SPA 5KD or 20KD (3% W/V), which could shield major histocompatibility antigen class I molecules (RT1-A) of corneal grafts. Skin grafts of Wistar rats were transplanted to SD rats. Then the splenic lymphocytes were isolated from SD rats. Subsequently, the lymphocytes were co-cultured with autologous corneal grafts or untreated corneal grafts and PEGylated grafts treated with mPEG-SPA 5KD or 20KD obtained from the counterpart skin donors, which were used as autologous control, allogeneic control, mPEG-SPA 5KD group and mPEG-SPA 20KD group, respectively. Lymphocyte proliferation was lower in mPEG-SPA 5KD group and mPEG-SPA 20KD group than in the allogeneic control. SD rats with corneal neovascularisation were used as recipients for high-risk corneal transplantation and were randomly divided into four groups: autologous control, allogeneic control, mPEG-SPA 5KD group and mPEG-SPA 20KD group. The recipients received corneal grafts from Wistar rats. Corneal graft survival was prolonged and graft rejection was reduced in the mPEG-SPA 5KD group and the mPEG-SPA 20KD group compared to the allogeneic control. Thus, we think that mPEG-SPA could immunologically camouflage corneal antigens to prolong corneal grafts survival in high-risk transplantation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Brote de legionelosis asociado a un balneario Legionella outbreak at a spa

    Directory of Open Access Journals (Sweden)

    E. Serrano Ibarbia

    2001-06-01

    Full Text Available En 1998 el inicio de la temporada de actividad de un balneario en Gipuzkoa coincidió con la detección de un brote de legionelosis asociado al mismo, lo cual condujo al cierre de la instalación y al estudio epidemiológico -casos y controles- y ambiental oportunos. Se definió como caso toda persona que durante su estancia en el balneario o durante los 10 días siguientes presentará neumonía o un cuadro febril compatible con fiebre de Pontiac.El estudio ambiental incluyó la inspección del balneario y entorno y muestreos de los sistemas sanitarios de agua y de los elementos de hidroterapia.De las 287 personas encuestadas de la Comunidad Autónoma Vasca, el 12.5% cumplían con la definición de caso; 9 casos presentaron neumonía y 26 fiebre de Pontiac. La curva epidémica se inició el 7 de mayo, alcanzando un pico los días 14 y 15 de mayo y finalizando el día 20. El riesgo de enfermar ajustado por edad, sexo y consumo de tabaco se asoció con la duración de la estancia en el balneario (OR=118.5, 95% I.C: 18.7-750.2 y con el uso de una piscina (OR=10.5, 95% I.C: 1.3-82.6. Se detecto L. pneumophila serogrupo1 en recuentos superiores a 103 ufc/l en diversos puntos de la red de hidroterapia y en la ducha de la habitación de uno de los enfermos. El análisis por electroforesis en campos pulsados de una muestra biológica y muestras ambientales permitió la confirmación genotípica. El establecimiento se abrió al público tras realizar un tratamiento de choque y comprobar que transcurridos 15 días no se detectó L. pneumophila en las muestras ambientales.The start of seasonal activity at a spa in Guipuzcoa coincided with the detection of an associated legionnaire outbreak in 1998. This led to the closure of the premises and to the carrying out of opportune environmental and epidemiological studies. The latter included case-control study. A case was defined as a person who, either during his stay or in a period of 10 days thereafter

  13. Can activity support influence image of a street?

    Science.gov (United States)

    Tamiami Fachrudin, Hilma

    2018-03-01

    Activity support may affect the formation of the image of a corridor and street. Form, place, and character of activity support in an area will have the function attraction and usefulness of its activities. The aim of this research is to analyze how the influence of activity support on the image of a street, in this case, Dr.Mansyur street which located in front of Universitas Sumatera Utara. Along the street, there are various activities that conducted from morning until evening. The method used is a quantitative method with observation and questionnaire techniques. A population of this study is visitors and students of architecture department from Universitas Sumatera Utara (USU) with sample number is 100 respondents for visitors and 100 respondents for students. Independent variables are activity support factors that consist of the type of activity, form, color, dimension, material, position and lighting. The dependent variable is imageability by [1]. Data were analyzed using logistic regression analysis. The results show that activity support influences image Dr. Mansyur street that has an image as a campus and culinary area and easy to identify.

  14. The influence of attitudes toward physical activity and sports

    Directory of Open Access Journals (Sweden)

    Ana Tereza Araújo

    2015-12-01

    Full Text Available Abstract Attitude is one of the most important predictor variables in relation to behavioral intentions regarding physical activity. Thus, this study aims to determine the influence of attitudes towards physical activity. The study comprised a sample of 1129 individuals (507 men and 622 women age between 12 and 58 years ( = 18 sd = 4.03. To collect the data, the Scale of Attitudes Towards Physical Activity and Sports (Dosil, 2002 was based on the Portuguese version (Cid, Alves, & Dosil, 2008. The results show that attitudes towards physical activity and sports are more positive in younger male individuals, who do not attend higher education, who regularly engage in physical activity and whose parents engage in physical/sports activity themselves.

  15. Influence of mammal fossorial activity on the soil fermentative activity in conditions of metallurgical production

    Directory of Open Access Journals (Sweden)

    S. M. Kirienko

    2010-09-01

    Full Text Available Effect of mammal fossorial activity as an ecological factor of the soil genesis intensification is studied. Enzymatic activity of soil as its ability to demonstrate a catalytic effect for various compounds transformation is examined. Variability of soil urease activity in technogenic conditions with the participation of animals is shown. The positive influence of animals’ activity on the catalitic ability of the investigated soils was determined. The statistically significant characteristics which have an influence on the urease activity in soil are found out.

  16. Radioprotector modifying influence upon the ion transport ATPase activities

    International Nuclear Information System (INIS)

    Dvoretsky, A.I.; Egorova, E.G.; Ananieva, T.V.; Kulikova, I.A.

    1993-01-01

    The effects of aminothiol and biogenic amine radioprotectors (β-mercaptoethylamine, AET, serotonin, dopamine, histamine) on the basic ion transport enzymes, such as Na, K-ATP ase and Mg, Ca-ATPase activities were investigated in the tissues of numerous organs, with different radiosensitivity in the wistar rats. Experimental results showed that intraperitoneal injection of the used radioprotectors caused preliminary inhibition of the Na, K-ATPase activity in tissues from organs with different radioresistance, but had no influence on the Mg, Ca-ATPase activity in membranes of erythrocytes and rat brain cells. (2 tabs.)

  17. Role of surfactant protein A (SP-A)/lipid interactions for SP-A functions in the lung.

    Science.gov (United States)

    Casals, C

    2001-01-01

    Surfactant protein A (SP-A), an oligomeric glycoprotein, is a member of a group of proteins named collectins that contain collagen-like and Ca(2+)-dependent carbohydrate recognition domains. SP-A interacts with a broad range of amphipathic lipids (glycerophospholipids, sphingophospholipids, glycosphingolipids, lipid A, and lipoglycans) that are present in surfactant or microbial membranes. This review summarizes SP-A/lipid interaction studies regarding the lipid system used (i.e., phospholipid vesicles, phospholipid monolayers, and lipids immobilized on silica or adsorbed on a solid support). The effect of calcium, ionic strength, and pH on the binding of SP-A to lipids and the subsequent lipid aggregation process is discussed. Current evidence suggests that hydrophobic-binding forces are involved in the peripherical association of SP-A to membranes. It is also proposed that fluid and liquid-ordered phase coexistence in surfactant membranes might favor partition of SP-A into those membranes. The binding of SP-A to surfactant membranes containing hydrophobic surfactant peptides makes possible the formation of a membrane reservoir in the alveolar fluid that is protected by SP-A against inactivation and improves the rate of surfactant film formation. In addition, the interaction of SP-A with membranes might enhance the affinity of SP-A for terminal carbohydrates of glycolipids or glycoproteins on the surface of invading microorganisms.

  18. Physical activity influences the immune system of breast cancer patients

    Directory of Open Access Journals (Sweden)

    Thorsten Schmidt

    2017-01-01

    Full Text Available It has been suggested that physical activity in breast cancer patients can not only improve quality of life. Influences on physical and psychological levels have been evaluated, but effects on the immune system of breast cancer patients are hardly known. A PubMed search identified relevant trials and meta-analyses from 1970 to 2013. This review summarizes the results of international studies and the current discussion of effects of physical activity on the immune system of breast cancer patients. Highlighted are effects of physical activity on the immune system. Seven original articles and 14 reviews included in this review. Two original and the review articles includes other tumor entities besides breast cancer.Evaluated methods such as dose-response relationships for exercise in oncology, hardly exist. Increased immunological anti-cancer activity due to physical activity is probably mediated via an increase in number and cytotoxicity of monocytes and natural killer cells and cytokines.

  19. Analysis of the radioactivity in the 'Elguea' spa, Villa Clara, Cuba

    International Nuclear Information System (INIS)

    Fernandez G, I.M.; Zerquera, J.T.; Carrazana G, J.; Capote F, E.; Rodriguez C, G.

    2006-01-01

    The 'Elguea' spa, located in the north coast of the county of Villa Clara, Cuba, is considered one of those more important spas of Latin America. The waters of this spa are rich in salts of chlorine, sodium, bromine, sulfides and its contain radon. As a result of measurements of environmental gamma dose rates carried out in the area of the spa, its were considered levels of dose between 0.13 and 2.3 mSv. The obtained results motivated that it was carried out a characterization, from the radiological point of view, of the spa. This characterization is of supreme importance to be able to evaluate the impact that it has and the discharges of its waters on the environment, as well as, those dose that the population potentially affected can receive by these discharges. With this end its were carried out quantitative determinations of those existent natural more significant radionuclides in different environmental objects coming from the area of the spa and its surroundings, as well as one characterization gamma 'in situ' of the same one. The obtained results are present in this work. (Author)

  20. Beneficial effects of spa treatment on functional status and quality of life of patients with rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Mustur Dušan

    2008-01-01

    Full Text Available INTRODUCTION Rheumatoid arthritis (RA is a chronic constantly deteriorating disease of unpredictable clinical course, with exacerbations, remissions and damaged joints. It leads to the loss of self-sufficiency, independence in performing many daily activities, decrease of working ability and invalidity. Beside physical factors, which are regarded as most responsible for the poorer quality of life of RA patients, psychological changes are also significant, such as the feeling of helplessness, hopelessness and depression. The goal of the treatment of patients with RA is to decrease illness symptoms, slow down the development of illness progression, improvement of physical functioning and provision of expert help to the RA patients to adapt to life. OBJECTIVE The aim of the study was to assess the influence of spa therapy on the functional condition and life quality of RA patients. METHODS The study involved 69 patients with RA (51 female and 18 male, on average aged 55.2±11.4 years, with illness duration 12.5±7.5 years, and were a part of a cohort from Norway, suffering of inflammatory rheumatism. All the patients came for four-week rehabilitation at the Institute for Physical Medicine, Rehabilitation and Rheumatology "Dr. Simo Milošević" in Igalo, Montenegro. The RA patients underwent treatment with mud compresses, mud, mineral and pearl baths, as well as with underwater shower massage (balneotherapy kinesitherapy and certain forms of electrotherapy with analgesic effects. The evaluation was done on admission and after completed physical therapy when we assessed RA patients' functional condition and quality of life. The functional condition was determined using the Modified Health Assessment Questionnaire (MHAQ, and the quality of life using the Medical Outcomes Study Short Form 36-item Questionnaire (SF-36, which encompassed eight life domains. RESULTS After completion of 28-dayspa therapy, RA patients showed a significant improvement in

  1. Parental influences on adolescent physical activity: a longitudinal study

    Directory of Open Access Journals (Sweden)

    Ayala Guadalupe X

    2007-02-01

    Full Text Available Abstract Background Physical inactivity is increasing among adolescents in the U.S., especially among girls. Despite growing evidence that parents are an important influence on adolescent health, few longitudinal studies have explored the causal relationship between parental influence and physical activity. This study examines how the relationships between parental influences and adolescent physical activity differ by gender and tests whether these relationships are mediated by adolescents' self-esteem and depression. Methods Data are from the National Longitudinal Study of Adolescent Health. The sample includes 13,246 youth, grades 7 to 12, interviewed in 1995 and again 1 year later. Logit models were used to evaluate parental influences on achieving five or more bouts of moderate to vigorous physical activity per week [MVPA] and whether the relationship between parental influence and MVPA was mediated by adolescents' level of self-esteem and depression. Results Family cohesion, parent-child communication and parental engagement positively predicted MVPA for both genders one year later (odds ratios and 95% confidence intervals for females, 1.09 [1.05–1.12], 1.13 [1.07–1.19], 1.25 [1.17–1.33] and males, 1.08 [1.04–1.11], 1.14 [1.07–1.23], 1.23 [1.14–1.33], respectively; however, parental monitoring did not (odds ratio and confidence intervals for females and males, 1.02 [.97–1.07]. For both females and males, self-esteem mediated the relationship between parental influence and physical activity. Depressive symptoms were only a mediator among males. Females reported higher levels of parent-child communication and lower family cohesion compared with males. There were no gender differences in levels of parental monitoring and engagement. Females had significantly lower levels of self-esteem and higher levels of depressive symptoms than males. Conclusion Strategies to promote physical activity among adolescents should focus on

  2. Separating active and passive influences on stomatal control of transpiration.

    Science.gov (United States)

    McAdam, Scott A M; Brodribb, Timothy J

    2014-04-01

    Motivated by studies suggesting that the stomata of ferns and lycophytes do not conform to the standard active abscisic acid (ABA) -mediated stomatal control model, we examined stomatal behavior in a conifer species (Metasequoia glyptostroboides) that is phylogenetically midway between the fern and angiosperm clades. Similar to ferns, daytime stomatal closure in response to moderate water stress seemed to be a passive hydraulic process in M. glyptostroboides immediately alleviated by rehydrating excised shoots. Only after prolonged exposure to more extreme water stress did active ABA-mediated stomatal closure become important, because foliar ABA production was triggered after leaf turgor loss. The influence of foliar ABA on stomatal conductance and stomatal aperture was highly predictable and additive with the passive hydraulic influence. M. glyptostroboides thus occupies a stomatal behavior type intermediate between the passively controlled ferns and the characteristic ABA-dependent stomatal closure described in angiosperm herbs. These results highlight the importance of considering phylogeny as a major determinant of stomatal behavior.

  3. IMPLEMENTATION OF EU DIRECTIVES FOR CERTIFICATION OF THE STAFF IN THE SPA BUSINESS IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Petya Kutincheva

    2013-07-01

    Full Text Available Implemented was a psychometric experiment for survey the opinion of the leading experts from the 4 and 5 stars hotels and the first SPA certified MSc - SPA managers. The summarized results from the study highlight that the priorities are related to improve the quality of the services in the SPA business. We establish the acute need for increasing professional qualification of the personnel and harmonize the Bulgarian legislation with the EU directives. In this regard it is important to implement the national classificatory with new professions and unified for this purpose the theoretical categories: “Results of advanced training", "knowledge", "practical skills" and "competencies" in educational and qualification degree: “Bachelor", "MasterSc" and "PhD ".

  4. Market segment of families with children: a new stimulus for modern Czech spa industry?

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    Darina Jelínková

    2017-06-01

    Full Text Available The paper deals with a comprehensive range of hotel services for families with children at spa facilities of the Czech Republic, in line with current trends and requirements of this market segment. The main goal of this paper is to determine the preferences, needs and requirements of families with children in terms of amenities and services offer at spa hotels designated specifically for this target group. The secondary goal is to determine the current state of hotel services and facilities of Czech First Class hotels, which are the holders of the Baby Friendly Certificate. Subsequently, service offerings of these spa hotels are compared with the existing range of services for families with children in the selected Czech spas. In conclusion, based on the information obtained from the analyses and marketing research, a solution of the services portfolio intended for the market segment of families with children is recommended here using marketing mix as applied to tourism.

  5. Solec Spa – worldwide unique properties of Polish health resort in the service of rural medicine

    Directory of Open Access Journals (Sweden)

    Marek L Grabowski

    2018-03-01

    Full Text Available Solec Spa is health resort in south-eastern Poland. Its unique balneorehabilitation significance worldwide is determined by chloride-iodine-sodium water with a high content of hydrogen sulphide. This water, classified as highly mineralized sodium-chloride (seltzer sulphide, bromide, iodide, boron water, contains naturally approximately 0.9 g/l divalent sulphur compounds, which is the highest concentration noted among the mineral waters of the world. The effectiveness of the Solec waters is proven in: inflammatory and autoimmunological locomotor system diseases, degenerative joint disorders (osteoarthritis, post-traumatic and post-operative orthopedic diseases, skin diseases and allergic disorders. One of the main indications for balneotherapy in Solec Spa and Busko Spa is chronic brucellosis.

  6. spa typing and antimicrobial resistance of Staphylococcus aureus from healthy humans, pigs and dogs in Tanzania

    DEFF Research Database (Denmark)

    Katakweba, Abdul S.; Muhairwa, Amandus P.; Espinosa-Gongora, Carmen

    2016-01-01

    . aureus carrier frequencies in dogs and humans were within the expected range and low in pigs. The S. aureus spa types circulating in the community were generally not shared by different hosts and majority of types belonged to known clones. Besides ampicillin resistance, moderate levels of antimicrobial......Introduction: Staphylococcus aureus is an opportunistic pathogen causing infections in humans and animals. Here we report for the first time the prevalence of nasal carriage, spa typing and antimicrobial resistance of S. aureus in a Tanzanian livestock community. Methodology: Nasal swabs were taken...... from 100 humans, 100 pigs and 100 dogs in Morogoro Municipal. Each swab was enriched in Mueller Hinton broth with 6.5% NaCl and subcultured on chromogenic agar for S. aureus detection. Presumptive S. aureus colonies were confirmed to the species level by nuc PCR and analysed by spa typing...

  7. Romanian spa tourism: a communist paradigm in a post communist era

    Directory of Open Access Journals (Sweden)

    George Erdeli

    2011-11-01

    Full Text Available Spa tourism is one of the oldest forms of tourism which continuously evolved in time as the leisure industry paradigm and the consumers’ behavior changed. Similar to other countries in Central and Eastern Europe, spa tourism is an old phenomenon in Romania which expanded to the dimensions of a well defined tourism industry during the mass tourism period which also corresponded to the communism epoch. Although severely affected by the major political and socio-economic changes which occurred after the Revolution in 1989, this industry coexists with new emergent forms of tourism orienting, itself towards new dimensions embraced by the contemporary leisure consumerism (e.g. medical tourism, cosmetic treatments. Lying on considerable balneal and climate resources and displaying an important communist heritage both in physical terms (large and massive tourism structures and in virtual and psychological terms (social supportive ticket granting system, Romanian spa tourism faces various challenges in the attempt to adapt in a new tourism era.

  8. Teaching Cultural Astronomy: On the Development and Evolution of the Syllabus at Bath Spa University and the University of Wales, Lampeter

    Science.gov (United States)

    Campion, Nick

    TheMaster of Arts in CulturalAstronomy andAstrology at the University of Wales, Lampeter, formerly taught at Bath Spa University in England, is the first degree of its kind in the world. (I shall refer to the discipline as Cultural Astronomy, with initial letters as upper case, and the phenomena which it studies as cultural astronomy, all lower case). My definition combines both the discipline and the phenomenon; 'Cultural astronomy: the use of astronomical knowledge, beliefs or theories to inspire, inform or influence social forms and ideologies, or any aspect of human behaviour. Cultural astronomy also includes the modern disciplines of ethnoastronomy and archaeoastronomy' (Campion 1997: 2).

  9. Streptococcus mutans SpaP binds to RadD of Fusobacterium nucleatum ssp. polymorphum.

    Science.gov (United States)

    Guo, Lihong; Shokeen, Bhumika; He, Xuesong; Shi, Wenyuan; Lux, Renate

    2017-10-01

    Adhesin-mediated bacterial interspecies interactions are important elements in oral biofilm formation. They often occur on a species-specific level, which could determine health or disease association of a biofilm community. Among the key players involved in these processes are the ubiquitous fusobacteria that have been recognized for their ability to interact with numerous different binding partners. Fusobacterial interactions with Streptococcus mutans, an important oral cariogenic pathogen, have previously been described but most studies focused on binding to non-mutans streptococci and specific cognate adhesin pairs remain to be identified. Here, we demonstrated differential binding of oral fusobacteria to S. mutans. Screening of existing mutant derivatives indicated SpaP as the major S. mutans adhesin specific for binding to Fusobacterium nucleatum ssp. polymorphum but none of the other oral fusobacteria tested. We inactivated RadD, a known adhesin of F. nucleatum ssp. nucleatum for interaction with a number of gram-positive species, in F. nucleatum ssp. polymorphum and used a Lactococcus lactis heterologous SpaP expression system to demonstrate SpaP interaction with RadD of F. nucleatum ssp. polymorphum. This is a novel function for SpaP, which has mainly been characterized as an adhesin for binding to host proteins including salivary glycoproteins. In conclusion, we describe an additional role for SpaP as adhesin in interspecies adherence with RadD-SpaP as the interacting adhesin pair for binding between S. mutans and F. nucleatum ssp. polymorphum. Furthermore, S. mutans attachment to oral fusobacteria appears to involve species- and subspecies-dependent adhesin interactions. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Spa therapy: can be a valid option for treating knee osteoarthritis?

    Science.gov (United States)

    Tenti, Sara; Cheleschi, Sara; Galeazzi, Mauro; Fioravanti, Antonella

    2015-08-01

    Osteoarthritis (OA) continues to be one of the leading causes of `years lived with disability' worldwide. Symptomatic knee OA is highly prevalent among people aged 50 years and over and is destined to become an ever more important healthcare problem. Current management of knee OA includes non-pharmacological and pharmacological treatments. Spa therapy is one of the most commonly used non-pharmacological approaches for OA in many European countries, as well as in Japan and Israel. Despite its long history and popularity, spa treatment is still the subject of debate and its role in modern medicine continues to be unclear. The objective of this review is to summarize the currently available information on clinical effects and mechanisms of action of spa therapy in knee OA. Various randomized controlled clinical trials (RCTs) were conducted to assess the efficacy and tolerability of balneotherapy and mud-pack therapy in patients with knee OA. Data from these clinical trials support a beneficial effect of spa therapy on pain, function and quality of life in knee OA that lasts over time, until 6-9 months after the treatment. The mechanisms by which immersion in mineral or thermal water or the application of mud alleviate suffering in OA are not fully understood. The net benefit is probably the result of a combination of factors, among which the mechanical, thermal and chemical effects are most prominent. In conclusion, spa therapy seems to have a role in the treatment of knee OA. Additional RCTs and further studies of mechanisms of action with high methodological quality are necessary to prove the effects of spa therapy.

  11. Ideologically motivated activism: How activist groups influence corporate social change activities

    NARCIS (Netherlands)

    den Hond, F.; de Bakker, F.G.A.; Hickman, G. R.

    2010-01-01

    Using insights from the social movement literature and institutional change theory, we explore how activism influences corporate social change activities. As the responsibility for addressing a variety of social issues is transferred from the state to the private sector, activist groups increasingly

  12. 76 FR 54403 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Science.gov (United States)

    2011-09-01

    ... Federal holidays. For service information identified in this proposed AD, contact Piaggio Aero Industries... Service Information Piaggio Aero Industries S.p.A. has issued Mandatory Service Bulletin No. 80-0304... Accomplishment Instructions of Piaggio Aero Industries S.p.A. Mandatory Service Bulletin No. 80-0304, dated July...

  13. Molecular analysis of virulent genes (coa and spa) of staphylococcus aureus involved in natural cases of bovine mastitis

    International Nuclear Information System (INIS)

    Khan, A.; Javed, M.T.; Mahmood, F.; Hussain, R.

    2013-01-01

    The present study was undertaken to determine the distribution and genotypic characteristics of Staphylococcus aureus isolates recovered from naturally occurring mastitis in cattle and buffaloes. For this purpose a total of 1445 lactating cattle (653) and buffaloes (792) present at two experimental livestock farms Okara (Bahadarnagar) and Sahiwal (Qadiarabad), in and around district Faisalabad and slaughtered at an abattoir due to low milk yield and were screened for mastitis. California Mastitis Test (CMT) was used to detect sub clinical mastitis. The positive quarter milk samples were collected for culturing of S. aureus isolates. taphylococcus aureus isolates were identified on the basis of growth features, biochemical characteristics, coagulase test and as well as amplification of coagulase (coa) and spa (spa-X) genes specific to its virulence. S. aureus isolates (n=265) were characterized by Polymerase chain reaction to determine the frequency of coagulase (coa) and spa (spa-X) genes. From these isolates the amplification of the coagulase (coa) gene yielded three different PCR products approximately 204bp to 490bp while spa (spa-X) gene produced five different products ranging in size from 190bp to 320bp. PCR revealed that from all the coagulase positive S. aureus isolates 261(98.5%) had spa (spa-X) gene. The results of the present study indicated that S. aureus isolates recovered from bovine mastitis were genetically different within and among the various herds which may provide essential and valuable strategies to control staphylococcal infections in future. (author)

  14. Molecular analysis of virulent genes (coa and spa) of staphylococcus aureus involved in natural cases of bovine mastitis

    Energy Technology Data Exchange (ETDEWEB)

    Khan, A.; Javed, M. T.; Mahmood, F. [University of Agriculture, Faisalabad (Pakistan). Dept. of Pathology; Hussain, R. [The Islamia Univ. of Bahawalpur, Pakistan (Pakistan). Dept. of Veterinary and Animal Sciences

    2013-12-15

    The present study was undertaken to determine the distribution and genotypic characteristics of Staphylococcus aureus isolates recovered from naturally occurring mastitis in cattle and buffaloes. For this purpose a total of 1445 lactating cattle (653) and buffaloes (792) present at two experimental livestock farms Okara (Bahadarnagar) and Sahiwal (Qadiarabad), in and around district Faisalabad and slaughtered at an abattoir due to low milk yield and were screened for mastitis. California Mastitis Test (CMT) was used to detect sub clinical mastitis. The positive quarter milk samples were collected for culturing of S. aureus isolates. taphylococcus aureus isolates were identified on the basis of growth features, biochemical characteristics, coagulase test and as well as amplification of coagulase (coa) and spa (spa-X) genes specific to its virulence. S. aureus isolates (n=265) were characterized by Polymerase chain reaction to determine the frequency of coagulase (coa) and spa (spa-X) genes. From these isolates the amplification of the coagulase (coa) gene yielded three different PCR products approximately 204bp to 490bp while spa (spa-X) gene produced five different products ranging in size from 190bp to 320bp. PCR revealed that from all the coagulase positive S. aureus isolates 261(98.5%) had spa (spa-X) gene. The results of the present study indicated that S. aureus isolates recovered from bovine mastitis were genetically different within and among the various herds which may provide essential and valuable strategies to control staphylococcal infections in future. (author)

  15. Comparing Whole-Genome Sequencing with Sanger Sequencing for spa Typing of Methicillin-Resistant Staphylococcus aureus

    DEFF Research Database (Denmark)

    Bartels, Mette Damkjaer; Petersen, Andreas; Worning, Peder

    2014-01-01

    spa typing of methicillin-resistant Staphylococcus aureus (MRSA) has traditionally been done by PCR amplification and Sanger sequencing of the spa repeat region. At Hvidovre Hospital, Denmark, whole-genome sequencing (WGS) of all MRSA isolates has been performed routinely since January 2013, and ...

  16. Radon exposure during treatment in some thermal spa centers in Greece

    International Nuclear Information System (INIS)

    Nikolopoulos, D.; Louizi, A.; Serefoglou, A.; Georgiou, E.; Vogiannis, E.; Halvadakis, C.

    2004-01-01

    Radon ( 222 Rn) present in the spa facilities has been identified as an agent of additional radiation burden both for bathers and the working personnel. Although some researchers have been concentrated on the health impact of radon activity transient increases due to water flow of domestically used water, limited work has been reported on this effect in spa facilities. The aim of this work was to study the exposure both of bathers and working personnel due to water flow under working conditions in some thermal spas in Greece. The spas studied were built at two locations in Greece; Lesvos Island and the city of Loutra- Edipsou. The study was performed between 1999 and 2003. Measurements involved determination of radon concentration in the waters of the thermal spas, monitoring of radon and short-lived decay product activity (both in attached and unattached form) and coarse particles (> 500 nm). Water radon concentration was measured by Alpha Guard PQ2000Pro of Genitron GmbH equipped with an appropriate unit (Aquakit). Indoor radon activity was monitored by Alpha Guard PQ2000Pro and EQF3023 of Sarad GmbH which was also used for monitoring of radon short-lived decay product activity. Coarse particle concentration measurements were performed by a GRIMM 1.104 Portable Dust Monitor. Measurements indoors were performed in the treatment room and in the reception room, if existing, under working conditions. Several procedures for bath filling and pouring out of the treatment room, during the measurements, were studied. Radon concentrations of thermal waters were found to lie in the range 1 Bq.L -1 and 304 Bq.L -1 . Some of these concentrations may be considered as elevated. Elevated (about 2-6 kBq.m -3 ) indoor radon concentrations were measured in the treatment rooms of the spas of Polichnitos, Eftalou and Loutra Edipsou. This found to be in accordance to the high radon potential of these spas, as detected out of the measurements of their thermal waters. Concentration

  17. Parents' perception of their influence on their child's physical activity.

    Science.gov (United States)

    VanDerworp, Gwendolyn Kay; Ryan, Sarah-Jane

    2016-03-01

    Childhood physical activity (PA) has declined in the western world recently. To combat child inactivity, government programs have been organized to promote PA within families. It is important for physiotherapists to understand the influence parents perceive to have on their child's PA habits in order to better encourage a positive parental influence. The purpose of this study is to explore how parents perceive their influence on their child/children's PA through an interpretative phenomenological analysis (IPA) approach. This qualitative study used a phenomenological approach with semi-structured interviews conducted with five participants. The interviews were analyzed using elements of IPA. Master themes developed with their corresponding subthemes: creating an environment of opportunity--logistics, opportunities through encouragement and PA within the family, barriers to PA--barriers created by parents and barriers created by external factors, and parent and child interactions--children communicating interest and disinterest in PA and parent's attitudes toward children's disinterest. The findings suggest that parents perceive themselves to have a greater positive influence on their children rather than negative. The barriers that parents create are not perceived to prevent their child's PA but rather restrict it. Many participants reported enjoying doing PA with their children and used PA as an opportunity for family time, indicating a dual purpose for PA. © The Author(s) 2014.

  18. Role of Diet in Influencing Rheumatoid Arthritis Disease Activity

    Science.gov (United States)

    Badsha, Humeira

    2018-01-01

    Background: Patients with Rheumatoid Arthritis (RA) frequently ask their doctors about which diets to follow, and even in the absence of advice from their physicians, many patients are undertaking various dietary interventions. Discussion: However, the role of dietary modifications in RA is not well understood. Several studies have tried to address these gaps in our understanding. Intestinal microbial modifications are being studied for the prevention and management of RA. Some benefits of vegan diet may be explained by antioxidant constituents, lactobacilli and fibre, and by potential changes in intestinal flora. Similarly, Mediterranean diet shows anti-inflammatory effects due to protective properties of omega-3 polyunsaturated fatty acids and vitamins, but also by influencing the gut microbiome. Gluten-free and elemental diets have been associated with some benefits in RA though the existing evidence is limited. Long-term intake of fish and other sources of long-chain polyunsaturated fatty acids are protective for development of RA. The benefits of fasting, anti-oxidant supplementation, flavanoids, and probiotics in RA are not clear. Vitamin D has been shown to influence autoimmunity and specifically decrease RA disease activity. The role of supplements such as fish oils and vitamin D should be explored in future trials to gain new insights in disease pathogenesis and develop RA-specific dietary recommendations. Conclusion: Specifically more research is needed to explore the association of diet and the gut microbiome and how this can influence RA disease activity. PMID:29515679

  19. Research data management and libraries: relationships, activities, drivers and influences.

    Directory of Open Access Journals (Sweden)

    Stephen Pinfield

    Full Text Available The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their

  20. Research data management and libraries: relationships, activities, drivers and influences.

    Science.gov (United States)

    Pinfield, Stephen; Cox, Andrew M; Smith, Jen

    2014-01-01

    The management of research data is now a major challenge for research organisations. Vast quantities of born-digital data are being produced in a wide variety of forms at a rapid rate in universities. This paper analyses the contribution of academic libraries to research data management (RDM) in the wider institutional context. In particular it: examines the roles and relationships involved in RDM, identifies the main components of an RDM programme, evaluates the major drivers for RDM activities, and analyses the key factors influencing the shape of RDM developments. The study is written from the perspective of library professionals, analysing data from 26 semi-structured interviews of library staff from different UK institutions. This is an early qualitative contribution to the topic complementing existing quantitative and case study approaches. Results show that although libraries are playing a significant role in RDM, there is uncertainty and variation in the relationship with other stakeholders such as IT services and research support offices. Current emphases in RDM programmes are on developments of policies and guidelines, with some early work on technology infrastructures and support services. Drivers for developments include storage, security, quality, compliance, preservation, and sharing with libraries associated most closely with the last three. The paper also highlights a 'jurisdictional' driver in which libraries are claiming a role in this space. A wide range of factors, including governance, resourcing and skills, are identified as influencing ongoing developments. From the analysis, a model is constructed designed to capture the main aspects of an institutional RDM programme. This model helps to clarify the different issues involved in RDM, identifying layers of activity, multiple stakeholders and drivers, and a large number of factors influencing the implementation of any initiative. Institutions may usefully benchmark their activities against the

  1. Major results and lessons learned for performance assessments of spent fuel geological disposal: the SPA project

    International Nuclear Information System (INIS)

    Baudoin, P.; Serres, C.; Certes, C.; Gay, D.

    2001-01-01

    This paper presents a summary of the results obtained in the framework of the SPA (spent fuel disposal performance assessment) project. The project was undertaken by ENRESA, E; GRS, D; IPSN, F; NRG, NL; SCK.CEN, B and VTT, FIN between May 1996 and April 1999. Devoted to the study of spent fuel disposal in various host rock formations (clay, crystalline rocks and salt formation), it notably had the objective to evaluate the long-term performance of different repository systems and to identify the most influential elements. The variety of concepts, sites and scenarios considered in the framework of this project provides a wide range of information from which some general conclusions can be drawn. Focusing on the work done in the case of granite host rock formations, this paper describes the various approaches adopted and states the main sources of differences. It particularly stresses the differences related to the geosphere and biosphere modelling. For the geosphere modelling, ENRESA, GRS and VTT use one dimensional discrete approaches to model the migration of contaminants through the geosphere taking into account for matrix diffusion, whereas IPSN uses a three dimensional continuum approach based on a single porosity model. The comparison of the biosphere conversion factors shows the high influence on the calculated radionuclide dose contributions that can results from biosphere modelling assumptions. It notably points out the differences existing between a simplified ''water drinking'' approach as implemented by VTT and a more classical one in which a wider range of exposure pathways are taken into account. (orig.)

  2. Solar activity influence on air temperature regimes in caves

    Science.gov (United States)

    Stoeva, Penka; Mikhalev, Alexander; Stoev, Alexey

    Cave atmospheres are generally included in the processes that happen in the external atmosphere as circulation of the cave air is connected with the most general circulation of the air in the earth’s atmosphere. Such isolated volumes as the air of caves are also influenced by the variations of solar activity. We discuss cave air temperature response to climate and solar and geomagnetic activity for four show caves in Bulgaria studied for a period of 46 years (1968 - 2013). Everyday noon measurements in Ledenika, Saeva dupka, Snezhanka and Uhlovitsa cave have been used. Temperatures of the air in the zone of constant temperatures (ZCT) are compared with surface temperatures recorded at meteorological stations situated near about the caves - in the towns of Vratsa, Lovech, Peshtera and Smolyan, respectively. For comparison, The Hansen cave, Middle cave and Timpanogos cave from the Timpanogos Cave National Monument, Utah, USA situated nearly at the same latitude have also been examined. Our study shows that the correlation between cave air temperature time series and sunspot number is better than that between the cave air temperature and Apmax indices; that t°ZCT is rather connected with the first peak in geomagnetic activity, which is associated with transient solar activity (CMEs) than with the second one, which is higher and connected with the recurrent high speed streams from coronal holes. Air temperatures of all examined show caves, except the Ledenika cave, which is ice cave show decreasing trends. On the contrary, measurements at the meteorological stations show increasing trends in the surface air temperatures. The trend is decreasing for the Timpanogos cave system, USA. The conclusion is that surface temperature trends depend on the climatic zone, in which the cave is situated, and there is no apparent relation between temperatures inside and outside the caves. We consider possible mechanism of solar cosmic rays influence on the air temperatures in caves

  3. Activating lay health influencers to promote tobacco cessation.

    Science.gov (United States)

    Muramoto, Myra L; Hall, John R; Nichter, Mark; Nichter, Mimi; Aickin, Mikel; Connolly, Tim; Matthews, Eva; Campbell, Jean Z; Lando, Harry A

    2014-05-01

    To evaluate the effect of tobacco cessation brief-intervention (BI) training for lay "health influencers," on knowledge, self-efficacy and the proportion of participants reporting BI delivery post-training. Randomized, community-based study comparing In-person or Web-based training, with mailed materials. In-person and Web-training groups had significant post-training cessation knowledge and self-efficacy gains. All groups increased the proportion of individuals reporting BIs at follow-up, with no significant between-group differences. Irrespective of participants' prior intervention experience, 80%-86% reported BIs within the past 90 days; 71%-79% reported >1 in the past 30. Web and In-person training significantly increase health influencer cessation knowledge and self-efficacy. With minimal prompting and materials, even persons without BI experience can be activated to encourage tobacco cessation.

  4. Effect of calorie restriction on spontaneous physical activity and body mass in mice divergently selected for basal metabolic rate (BMR).

    Science.gov (United States)

    Brzęk, Paweł; Gębczyński, Andrzej K; Książek, Aneta; Konarzewski, Marek

    2016-07-01

    Spontaneous physical activity (SPA) represents an important component of daily energy expenditures in animals and humans. Intra-specific variation in SPA may be related to the susceptibility to metabolic disease or obesity. In particular, reduced SPA under conditions of limited food availability may conserve energy and prevent loss of body and fat mass ('thrifty genotype hypothesis'). However, both SPA and its changes during food restriction show wide inter-individual variations. We studied the effect of 30% caloric restriction (CR) on SPA in laboratory mice divergently selected for high (H-BMR) and low (L-BMR) basal metabolic rate. Selection increased SPA in the H-BMR line but did not change it in the L-BMR mice. This effect reflected changes in SPA intensity but not SPA duration. CR increased SPA intensity more strongly in the L-BMR line than in the H-BMR line and significantly modified the temporal variation of SPA. However, the initial between-line differences in SPA were not affected by CR. Loss of body mass during CR did not differ between both lines. Our results show that the H-BMR mice can maintain their genetically determined high SPA under conditions of reduced food intake without sacrificing their body mass. We hypothesize that this pattern may reflect the higher flexibility in the energy budget in the H-BMR line, as we showed previously that mice from this line reduced their BMR during CR. These energy savings may allow for the maintenance of elevated SPA in spite of reduced food intake. We conclude that the effect of CR on SPA is in large part determined by the initial level of BMR, whose variation may account for the lack of universal pattern of behavioural responses to CR. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Tracing How Normative Messages May Influence Physical Activity Intention.

    Science.gov (United States)

    van Bavel, René; Esposito, Gabriele; Baranowski, Tom; Duch-Brown, Néstor

    2017-04-01

    Normative messages have been shown to increase intention to do physical activity. We traced how "positive" and "negative" normative messages influenced physical activity intention by comparing constructs of the model of goal-directed behavior with descriptive norms (MGDB + DNs) across control and treatment groups in an experiment. For this purpose, 16-24-year-old respondents (n = 1,200) in Bulgaria, Croatia, and Romania were asked about their age, sex, and levels of physical activity before being exposed to positive and negative normative messages and completing a questionnaire with MGDB + DNs scales. Different MGDB + DNs constructs were influenced by the normative messages: compared with the control, the negative message group showed stronger attitudes (p = .003) and the positive message group showed higher positive anticipated emotions (p = .005). The positive message's effect is consistent with the literature on conformity to social norms. The negative message's effect lends itself to interpretations based on social identity and deviance regulation theories.

  6. Lithium carbonate tablets. Preparation techniques influence over active ingredient liberation

    International Nuclear Information System (INIS)

    Bueno, J.H.F.; Oliveira, A.G. de; Toledo Salgado, P.E. de

    1989-01-01

    Lithium carbonate tablets, prepared using wet and dry granulation, were assessed in vitro so as to determine the active ingredient dissolution. In this study, standardized formulations were used and developed with usual adjuvants (lactose - maize starch). Parallel to the dissolution testing. The influence of the preparation process over some physical characteristics (hardness, friability and disintegration) was also analysed. Although a better performance was observed of tables prepared using dry granulation, the authors concluded that the wet process is more suitable in preparing tables with the mentioned drug. (author)

  7. 75 FR 12167 - Virginia Graeme Baker Pool and Spa Safety Act; Public Accommodation

    Science.gov (United States)

    2010-03-15

    ... pool or spa that is ``open exclusively to patrons of a hotel or other public accommodations facility... Web site at http://www.cpsc.gov . B. Legal Analysis In adopting a reasonable interpretation of... ``an inn, hotel, motel, or other place of lodging, except for an establishment located within a...

  8. 76 FR 62605 - Virginia Graeme Baker Pool and Spa Safety Act; Interpretation of Unblockable Drain

    Science.gov (United States)

    2011-10-11

    ... the VGB Act defines an ``unblockable drain'' as ``a drain of any size and shape that a human body... intentions. They claim that for this reason, backup systems are necessary, and a swimming pool or spa with a... of an ``unblockable drain,'' at 16 CFR 1450.2(b) and believe it was in error. Regardless of the size...

  9. [Measurement of soil organic matter and available K based on SPA-LS-SVM].

    Science.gov (United States)

    Zhang, Hai-Liang; Liu, Xue-Mei; He, Yong

    2014-05-01

    Visible and short wave infrared spectroscopy (Vis/SW-NIRS) was investigated in the present study for measurement of soil organic matter (OM) and available potassium (K). Four types of pretreatments including smoothing, SNV, MSC and SG smoothing+first derivative were adopted to eliminate the system noises and external disturbances. Then partial least squares regression (PLSR) and least squares-support vector machine (LS-SVM) models were implemented for calibration models. The LS-SVM model was built by using characteristic wavelength based on successive projections algorithm (SPA). Simultaneously, the performance of LSSVM models was compared with PLSR models. The results indicated that LS-SVM models using characteristic wavelength as inputs based on SPA outperformed PLSR models. The optimal SPA-LS-SVM models were achieved, and the correlation coefficient (r), and RMSEP were 0. 860 2 and 2. 98 for OM and 0. 730 5 and 15. 78 for K, respectively. The results indicated that visible and short wave near infrared spectroscopy (Vis/SW-NIRS) (325 approximately 1 075 nm) combined with LS-SVM based on SPA could be utilized as a precision method for the determination of soil properties.

  10. LHC suppliers win Golden Hadron awards : Sandro Ferraris and Guiseppi Ginola from Simic SpA

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    Simic SpA (Italy) received its award for manufacturing the vacuum vessels for the superconducting dipoles. The 937 blue cylinders manufactured by Simic will provide the thermal insulation for the magnets. Measuring 15 metres in length and 1 metre in diameter, they are designed to withstand a vacuum of 10-4 Pa.

  11. Rickett’s Dry Cleaning Site, Village of Ballston Spa, NY

    Science.gov (United States)

    The Rickett’s Dry Cleaning Site is located in a mixed commercial and residential area in the village of Ballston Spa on County Route 50. The site was the location of a family owned dry cleaner/ laundromat that went out of business in 2014. The site has

  12. Objectification of a Choice of a Spa Treatment Plan for Arthritis of the Hip Joint

    Czech Academy of Sciences Publication Activity Database

    Och, F.; Medonos, J.; Hanzlíček, P.; Valenta, Zdeněk; Dvořák, V.; Zvárová, Jana

    2013-01-01

    Roč. 1, č. 1 (2013), s. 10-10 ISSN 1805-8698. [EFMI 2013 Special Topic Conference. 17.04.2013-19.04.2013, Prague] Institutional support: RVO:67985807 Keywords : decision-support * spa treatment * hip arthritis * statistical analysis Subject RIV: IN - Informatics, Computer Science

  13. Solar car park in a spa town; Das Solarparkhaus an der Kurpromenade

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, Willi

    2010-11-23

    Bad Lippspringe is the first spa town in the German state of Nordrhein-Westfalen that installed a solar park garage. The roof consists of semistransparent solar modules that ensure daylighting even in the winter season. There are safety nets below the modules to protect cars and persons from injuries in case of glassbreak. (orig.)

  14. The system of processing and analysis of the parameters to be controlled of the 'Ukrytie' (SPA)

    International Nuclear Information System (INIS)

    Shcherbin, V.N.; Kravchuk, T.A.; Nenakhov, A.N.

    1998-01-01

    Processing system and analysis of parameters to be controlled (SPA) is an integrated system monitor control, which unites complexes of technical facilities with methods of remote control and diagnostics of object 'Ukrytie'. System executes checking, diagnosing analytical, prognostic, scholastic-simulator and scientifically-methodical functions, describing current condition of the 'Ukrytie', with the issue of possible emergency situation descriptions

  15. Constructing a Professional: Gendered Knowledge in the (Self-)Positioning of Skin and Spa Therapy Students

    Science.gov (United States)

    Bredlöv, Eleonor

    2017-01-01

    This study outlines the self-positioning of skin and spa therapy students. More specifically, it focuses how they position themselves as professionals in terms of knowledge, and how gender is at play throughout this process. Drawing on a poststructural approach, inspired by Foucault and feminist theory, regularities of description and…

  16. 76 FR 60396 - Airworthiness Directives; Piaggio Aero Industries S.p.A. Airplanes

    Science.gov (United States)

    2011-09-29

    ...., Washington, DC 20590, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For service... on other P.180 aeroplanes, and Piaggio Aero Industries (PAI) had issued Service Bulletin (SB) No. 80... information by examining the MCAI in the AD docket. Relevant Service Information Piaggio Aero Industries S.p.A...

  17. 78 FR 36691 - Airworthiness Directives; Piaggio Aero Industries S.p.A Airplanes

    Science.gov (United States)

    2013-06-19

    ...., Washington, DC 20590, between 9 a.m. and 5 p.m., Monday through Friday, except Federal holidays. For service... condition, Piaggio Aero Industries (PAI) issued Service Bulletin (SB) 80-0345 to provide instructions for... in the AD docket. Relevant Service Information Piaggio Aero Industries S.p.A. has issued Mandatory...

  18. 76 FR 27872 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model P-180 Airplanes

    Science.gov (United States)

    2011-05-13

    ... through Friday, except Federal holidays. For service information identified in this AD, contact Piaggio... accomplishment instructions of Piaggio Aero Industries Alert Service Bulletin ASB- 80-0324, step 5, this AD.... Relevant Service Information PIAGGIO AERO INDUSTRIES S.p.A has issued Service Bulletin (Mandatory) N.: 80...

  19. 78 FR 69600 - Airworthiness Directives; Piaggio Aero Industries S.p.A Airplanes

    Science.gov (United States)

    2013-11-20

    ... p.m., Monday through Friday, except Federal holidays. For service information identified in this.... To address this potential unsafe condition, Piaggio Aero Industries (PAI) issued Service [[Page 69601... Service Information Piaggio Aero Industries S.p.A. has issued Mandatory Service Bulletin No.: 80-0381, Rev...

  20. 77 FR 27144 - Airworthiness Directives; Agusta S.p.A. Helicopters

    Science.gov (United States)

    2012-05-09

    ... Agusta, S.p.A., Via Giovanni Agusta 520, 21017 Cascina Costa di Samarate (VA), Italy, ATTN: Giovanni... written comments, data, or views. We also invite comments relating to the economic, environmental, energy.... Discussion The European Aviation Safety Agency (EASA), which is the Technical Agent for Italy, a Member State...

  1. Thompson’s Spa: The Most Famous Lunch Counter in the World

    Directory of Open Access Journals (Sweden)

    Peter Szende

    2012-09-01

    Full Text Available Thompson’s Spa in Boston was one of the most celebrated restaurant companies in America at the turn of the twentieth century. Founder Charles Eaton was a pioneer in production and service methods, who developed a variety of innovative mechanical systems. This article describes the founding, growth, and eventual decline of the company during the period 1882 to 1968.

  2. Structure of Spa15, a type III secretion chaperone from Shigella flexneri with broad specificity

    NARCIS (Netherlands)

    Eerde, André van; Hamiaux, Cyril; Pérez, Javier; Parsot, Claude; Dijkstra, Bauke W.

    2004-01-01

    Type III secretion (TTS) systems are used by many Gram-negative pathogens to inject virulence proteins into the cells of their hosts. Several of these virulence effectors require TTS chaperones that maintain them in a secretion-competent state. Whereas most chaperones bind only one effector, Spa15

  3. Cost-effectiveness of Spa treatment for fibromyalgia: general health improvement is not for free

    NARCIS (Netherlands)

    Zijlstra, T.R.; Braakman-Jansen, Louise Marie Antoinette; Taal, Erik; Rasker, Johannes J.; van de Laar, Mart A F J

    2007-01-01

    Objectives: To estimate the cost-effectiveness of an adjuvant treatment course of spa treatment compared with usual care only in patients with fibromyalgia syndrome (FM). - Methods: 134 patients with FM, selected from a rheumatology outpatient department and from members of the Dutch FM patient

  4. Combined spa-exercise therapy is effective in patients with ankylosing spondylitis: a randomized controlled trial

    NARCIS (Netherlands)

    van Tubergen, A.; Landewé, R.; van der Heijde, D.; Hidding, A.; Wolter, N.; Asscher, M.; Falkenbach, A.; Genth, E.; Thè, H. G.; van der Linden, S.

    2001-01-01

    To determine the efficacy of combined spa-exercise therapy in addition to standard treatment with drugs and weekly group physical therapy in patients with ankylosing spondylitis (AS). A total of 120 Dutch outpatients with AS were randomly allocated into 3 groups of 40 patients each. Group 1 (mean

  5. Erosion influences the seismicity of active thrust faults.

    Science.gov (United States)

    Steer, Philippe; Simoes, Martine; Cattin, Rodolphe; Shyu, J Bruce H

    2014-11-21

    Assessing seismic hazards remains one of the most challenging scientific issues in Earth sciences. Deep tectonic processes are classically considered as the only persistent mechanism driving the stress loading of active faults over a seismic cycle. Here we show via a mechanical model that erosion also significantly influences the stress loading of thrust faults at the timescale of a seismic cycle. Indeed, erosion rates of about ~0.1-20 mm yr(-1), as documented in Taiwan and in other active compressional orogens, can raise the Coulomb stress by ~0.1-10 bar on the nearby thrust faults over the inter-seismic phase. Mass transfers induced by surface processes in general, during continuous or short-lived and intense events, represent a prominent mechanism for inter-seismic stress loading of faults near the surface. Such stresses are probably sufficient to trigger shallow seismicity or promote the rupture of deep continental earthquakes up to the surface.

  6. Disinfection of herbal spa pool using combined chlorine dioxide and sodium hypochlorite treatment.

    Science.gov (United States)

    Hsu, Ching-Shan; Huang, Da-Ji

    2015-02-01

    The presence of pathogenic microorganisms in public spa pools poses a serious threat to human health. The problem is particularly acute in herbal spas, in which the herbs and microorganisms may interact and produce undesirable consequences. Accordingly, the present study investigated the effectiveness of a combined disinfectant containing chlorine dioxide and sodium hypochlorite in improving the water quality of a public herbal spa in Taiwan. Water samples were collected from the spa pool and laboratory tests were then performed to measure the variation over time of the microorganism content (total CFU and total coliforms) and residual disinfectant content given a single disinfection mode (SDM) with disinfectant concentrations of 5.2 × 10, 6.29 × 10, 7.4 × 10, and 11.4 × 10(-5) N, respectively. Utilizing the experience gained from the laboratory tests, a further series of on-site investigations was performed using three different disinfection modes, namely SDM, 3DM (once every 3 h disinfection mode), and 2DM (once every 2 h disinfection mode). The laboratory results showed that for all four disinfectant concentrations, the CFU concentration reduced for the first 6 h following SDM treatment, but then increased. Moreover, the ANOVA results showed that the sample treated with the highest disinfectant concentration (11.4 × 10(-5) N) exhibited the lowest rate of increase in the CFU concentration. In addition, the on-site test results showed that 3DM and 2DM treatments with disinfectant concentrations in excess of 9.3 × 10 and 5.5 × 10(-5) N, respectively, provided an effective reduction in the total CFU concentration. In conclusion, the experimental results presented in this study provide a useful source of reference for spa businesses seeking to improve the water quality of their spa pools.

  7. Influence Factors of Sexual Activity for Internal Migrants in China

    Directory of Open Access Journals (Sweden)

    Junguo Zhang, PhD candidate

    2018-06-01

    indicate that specific demographic, socioeconomic, and epidemiological characteristics influenced sexual frequency among migrants. Sexual communication as the largest effect predictor to sexual frequency should be paid more attention to, to improve sexual activity of migrants.Zhang J, Wu J, Li Y, et al. Influence factors of sexual activity for internal migrants in China. J Sex Med 2018;6:97–107. Key Words: Sexual Activity, Influence Factors, Migrants, China, Quantile Regression

  8. Clinical and biochemical effects of a 3-week program of diet combined with spa therapy in obese and diabetic patients: a pilot open study

    Science.gov (United States)

    Fioravanti, Antonella; Adamczyk, Przemysław; Pascarelli, Nicola Antonio; Giannitti, Chiara; Urso, Renato; Tołodziecki, Michał; Ponikowska, Irena

    2015-07-01

    Obesity is a major risk factor for arterial hypertension, coronary artery disease, dyslipidemias, and type 2 diabetes. Spa therapy has long been used for treating obesity and its comorbidities. Enlargement of adipose tissue has been linked to a dysregulation of adipokine secretion and adipose tissue inflammation. Adipokines are currently investigated as potential drug targets in these conditions. Our primary aim was to assess the clinical efficacy of a 3-week program of diet combined with spa therapy in obese patients with and without type 2 diabetes. The secondary aim was to examine whether this combined program influences the response of serum levels of leptin, adiponectin, visfatin, and high-sensitivity C-reactive protein. Fifty obese males were enrolled and 21 of these featured a type 2 diabetes. During the 3-week period of the study, the patients were on a 1,000-kcal diet and were involved in mineral bath and total body's mud-pack applications (15 procedures). Patients were assessed at baseline and at the end of the therapy for clinical and biochemical parameters (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, glycemia, and adipokines). We showed that a 3-week program of spa therapy in obese patients induced significant decrease of body weight, body mass index, triglycerides, total cholesterol, low-density lipoprotein (LDL) cholesterol, glycemia, and serum levels of leptin and high-sensitivity C-reactive protein. So, a cycle of mud-bath therapy associated with a controlled diet may be a promising treatment for obesity and type 2 diabetes decreasing body weight and many risk factors for atherosclerosis and metabolic syndrome.

  9. SOCIAL CAPITAL FRAMEWORK AND ITS INFLUENCE ON THE ENTREPRENEURIAL ACTIVITY

    Directory of Open Access Journals (Sweden)

    Badea Mihaela-Raluca

    2013-07-01

    Full Text Available The aim of this article is to understand the theoretical framework of the social capital concept, based on different approaches identified in the literature and highlight the direct influence social capital has on the entrepreneurial personality characteristics of individuals and organizations. The objectives of the paper focus first on conceptualizing the notion of social capital, by acknowledging the social capital structure and components in the acceptation of the most popular scholars in the research field, the sources of social capital and its role in building social economy; further on, the article explores the influence of social capital in the creation of innovation and economic growth, its dimensions in the entrepreneurial process and the definition of the instruments of measurement, including indicators of trust-generalized and institutional, number of social networks, associational activities-passive and active membership and civic norms. The paper gathers some of the outcomes of different researches conducted in the literature with respect to the positive relationship between social capital dimensions and entrepreneurship, through attracting the right potential of human capital and the required level of financial capital, reducing the transaction costs, identifying new market opportunities and leveraging the social networks, transfer and knowledge overflow and information channels, enabling the launch and the survival of business venture and help gain competitive advantage that would ensure sustainability and success. The case studies referenced in this article use various approaches of highlighting the social capital as a key enabler and not necessarily a generator of entrepreneurial activity, by analyzing the likelihood to launch new ventures based on the interactions with key partners and exchange of information, the sustainability and success of a start up or push/pull factors that determine an entrepreneur to enter the new

  10. Influence of pulmonary surfactant on in vitro bactericidal activities of amoxicillin, ceftazidime, and tobramycin

    NARCIS (Netherlands)

    A. van 't Veen (Annemarie); J.W. Mouton (Johan); D.A.M.P.J. Gommers (Diederik); J.A.J.W. Kluytmans (Jan); P. Dekkers; B.F. Lachmann (Burkhard)

    1995-01-01

    textabstractThe influence of a natural pulmonary surfactant on antibiotic activity was investigated to assess the possible use of exogenous surfactant as a vehicle for antibiotic delivery to the lung. The influence of surfactant on the bactericidal activity of

  11. Influence of metabolism on endocrine activities of bisphenol S.

    Science.gov (United States)

    Skledar, Darja Gramec; Schmidt, Jan; Fic, Anja; Klopčič, Ivana; Trontelj, Jurij; Dolenc, Marija Sollner; Finel, Moshe; Mašič, Lucija Peterlin

    2016-08-01

    Bisphenol S (BPS; bis[4-hydroxyphenyl]sulfone) is commonly used as a replacement for bisphenol A in numerous consumer products. The main goal of this study was to examine the influence of different metabolic reactions that BPS undergoes on the endocrine activity. We demonstrate that hydroxylation of the aromatic ring of BPS, catalyzed mainly by the cytochrome P450 enzymes CYP3A4 and CYP2C9, is its major in-vitro phase I biotransformation. Nevertheless, coupled oxidative-conjugative reactions analyses revealed that glucuronidation and formation of BPS glucuronide is the predominant BPS metabolic pathway. BPS reactive metabolites that can be tracked as glutathione conjugates were not detected in the present study. Two in-vitro systems were used to evaluate the endocrine activity of BPS and its two main metabolites, BPS glucuronide and hydroxylated BPS 4-(4-hydroxy-benzenesulfonyl)-benzene-1,2-diol (BPSM1). In addition, we have tested two structural analogs of BPS, bis[4-(2-hydroxyetoxy)phenyl]sulfone (BHEPS) and 4,4-sulfonylbis(2-methylphenol) (dBPS). The test systems were yeast cells, for evaluating estrogenic and androgenic activities, and the GH3.TRE-Luc reporter cell line for measuring thyroid hormone activity. BPS and BPSM1 were weak agonists of the estrogen receptor, EC50 values of 8.4 × 10(-5) M and 6.7 × 10(-4) M, respectively. Additionally, BPSM1 exhibited weak antagonistic activity toward the thyroid hormone receptor, with an IC50 of 4.3 × 10(-5) M. In contrast to BPSM1, BPS glucuronide was inactive in these assays, inhibiting neither the estrogen nor the thyroid hormone receptors. Hence, glucuronidation appears to be the most important pathway for both BPS metabolism and detoxification. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Influence of nano-dispersive modified additive on cement activity

    Energy Technology Data Exchange (ETDEWEB)

    Sazonova, Natalya, E-mail: n.a.sazonova@mail.ru; Badenikov, Artem, E-mail: rector@agta.ru; Ivanova, Elizaveta, E-mail: lisik-iva@mail.ru [Angarsk State Technical University, 60, Tchaykovsky St., 665835, Angarsk (Russian Federation); Skripnikova, Nelli, E-mail: nks2003@mail.ru [Tomsk State University of Architecture and Building, 2, Solyanaya Sq., 634003, Tomsk (Russian Federation)

    2016-01-15

    In the work the influence of single-walled carbon nanotubes (SWCNT) on the cement activity and the processes of structure formation of the hardened cement paste in different periods of hydration are studied. The changes in the kinetic curves of the sample strength growth modified with SWCNT in amount of 0.01 and 0.0005 % are stipulated by the results of differential scanning colorimetry, scanning electronic and ionic microscopy, X-ray-phase analysis. It was found that the nano-modified additive may increase in the axis compressive strength of the system by 1.4–6.3 fold relatively to the reference samples and may reach 179.6 MPa. It may intensify the hydration process of calcium silicates as well as influence on the matrix of hardened cement paste. The studies are conducted on the structural changes in the hardened cement paste, the time periods of increase and decrease of the compressive strength of the samples, the amount of the calcium hydroxide and tobermorite-like gel as well as the degree of hydration C{sub 3}S and β-C{sub 2}S.

  13. Influence of muscle groups' activation on proximal femoral growth tendency.

    Science.gov (United States)

    Yadav, Priti; Shefelbine, Sandra J; Pontén, Eva; Gutierrez-Farewik, Elena M

    2017-12-01

    Muscle and joint contact force influence stresses at the proximal growth plate of the femur and thus bone growth, affecting the neck shaft angle (NSA) and femoral anteversion (FA). This study aims to illustrate how different muscle groups' activation during gait affects NSA and FA development in able-bodied children. Subject-specific femur models were developed for three able-bodied children (ages 6, 7, and 11 years) using magnetic resonance images. Contributions of different muscle groups-hip flexors, hip extensors, hip adductors, hip abductors, and knee extensors-to overall hip contact force were computed. Specific growth rate for the growth plate was computed, and the growth was simulated in the principal stress direction at each element in the growth front. The predicted growth indicated decreased NSA and FA (of about [Formula: see text] over a four-month period) for able-bodied children. Hip abductors contributed the most, and hip adductors, the least, to growth rate. All muscles groups contributed to a decrease in predicted NSA ([Formula: see text]0.01[Formula: see text]-0.04[Formula: see text] and FA ([Formula: see text]0.004[Formula: see text]-[Formula: see text]), except hip extensors and hip adductors, which showed a tendency to increase the FA ([Formula: see text]0.004[Formula: see text]-[Formula: see text]). Understanding influences of different muscle groups on long bone growth tendency can help in treatment planning for growing children with affected gait.

  14. Influences on seizure activity in pregnant women with epilepsy

    DEFF Research Database (Denmark)

    Sabers, Anne

    2009-01-01

    This study evaluated whether referral to a specialized epilepsy clinic prior to pregnancy influences seizure activity during pregnancy. In addition, folic acid supplementation prior to pregnancy as a marker of intent to conceive was used to evaluate whether the use of folic acid at the time......). Seizure deterioration was significantly lower in group 1 than in group 2: 9% versus 32% (Pfolic acid supplements was significantly higher in group 1 (P... of conception correlates with the risk of seizure deterioration in pregnancy. The study population consisted of patients who had been followed in a specialized epilepsy clinic before conception (group 1, n=46) and patients who were referred to the clinic after the pregnancy was recognized (group 2, n=44...

  15. [Factors influencing research activity of Andalusian nurses and improvement strategies].

    Science.gov (United States)

    López Alonso, Sergio R; Gálvez González, María; Amezcua, Manuel

    2013-04-01

    To identify factors influencing research activity of Andalusian nurses and to find improvement strategies. Qualitative research using SWOT analysis (weaknesses, threats, strengths, opportunities). Nurses were selected deliberately in eight groups according to predetermined criteria. Analysis included categorization and relationship of factors and strategies. 81 participants were included in groups of 7-12 range. 45 categories were identified with 212 factors: 12 weaknesses (50 factors), 10 strengths (44 factors), 12 threats (68 factors) and 11 opportunities (50 factors). In addition, 32 categories were identified with 53 strategies: 14 categories of W-T strategies (42 strategies), 3 categories of S-T strategies (11 strategies), 5 categories of W-O strategies (13 strategies) and 10 categories of S-O strategies (41 strategies). Nurses identified numerous factors, mainly threats. The strategies are focused on W-T but they also suggest many but weak 5-0 strategies due to the low potential of the opportunities and strengths perceived.

  16. The influence of experimentally induced pain on shoulder muscle activity

    DEFF Research Database (Denmark)

    Diederichsen, L.P.; Winther, A.; Dyhre-Poulsen, P.

    2009-01-01

    healthy men (range 22-27 years), with no history of shoulder or cervical problems, were included in the study. Pain was induced by 5% hypertonic saline injections into the supraspinatus muscle or subacromially. Seated in a shoulder machine, subjects performed standardized concentric abduction (0A degrees......Muscle function is altered in painful shoulder conditions. However, the influence of shoulder pain on muscle coordination of the shoulder has not been fully clarified. The aim of the present study was to examine the effect of experimentally induced shoulder pain on shoulder muscle function. Eleven...... muscles. EMG was recorded before pain, during pain and after pain had subsided and pain intensity was continuously scored on a visual analog scale (VAS). During abduction, experimentally induced pain in the supraspinatus muscle caused a significant decrease in activity of the anterior deltoid, upper...

  17. Influence of hexavanadates on Na+/K+- ATPase activity

    Directory of Open Access Journals (Sweden)

    Zdravković Aleksandra

    2016-01-01

    Full Text Available Introduction: There is a great interest in use of polioximetalates in clinical medicine, primary as antibacterial, antiviral and antitumoral agents. Considering the key role of Na+/ K+- ATPase in normal functioning of most animal cells, as well as pivotal roles in cancer cell migration, the aim of this paper was to examine the influence of new synthesized hexavandates [V6-CH3][Na]2, [V6-NO2][TBA]2, [V6-C3][H]2, [V6-C5d][TBA]2 on Na+/K+- ATPase activity. Material and methods: The enzymatic activity of porcine cerebral cortex Na+/K+- ATPase was followed in both the absence and presence of increasing concentration of [V6-CH3] [Na]2, [V6-NO2][TBA]2, [V6-C3][H]2, [V6-C5d][TBA]2 (within the range 10-8 - 10-3 mol/L. The released Pi, liberated from the enzymatic hydrolysis of ATP, was determined by spectrophotometric method, using Perkin Elmer Lambda 35 UV-VIS spectrophotometer. Results: Investigated compounds inhibit the activity of Na+/K+ ATPase in dose-dependent manner within the investigated range. Obtained results indicate that all investigated compounds inhibit the Na+/K+ ATPase activity, but with different inhibiting power. [V6-NO2] [TBA]2 (IC50 = 1,87 × 10-5 mol/L was the most potent inhibitor of Na+/K+ ATPase, while [V6-C5d][TBA]2 showed the least potent inhibiting power (IC50 = 1,31 × 10-4 mol/L . The results are consistent with previously published concentration-dependent inhibitory effect of polyoxometalates (including polioxovandates on ATPase activity from different model syistems. Conclusion: Based on the results, we can conclude that the examined compounds inhibit Na+/K+- ATPase activity in a dose-dependent manner. Inhibiting power of tested hexavanadates are different, and weaker than inhibiting power of decavanadates (tested earlier on Na+/K+- ATPase activity, which is probably due to differences in charge, size and shape of these polioxometalates. Considering the role of this enzymes in the functioning of healthy cells and the

  18. Effect of a steam foot spa on geriatric inpatients with cognitive impairment: a pilot study

    Science.gov (United States)

    Koike, Yoshihisa; Kondo, Hideki; Kondo, Satoshi; Takagi, Masayuki; Kano, Yoshio

    2013-01-01

    Purpose To investigate whether a steam foot spa improves cognitive impairment in geriatric inpatients. Methods Geriatric inpatients with cognitive impairment were given a steam foot spa treatment at 42°C for 20 minutes for 2 weeks (5 days/week). Physiological indicators such as blood pressure, percutaneous oxygen saturation, pulse, tympanic temperature, and sleep time and efficiency were assessed. Cognitive function and behavioral and psychological symptoms of dementia were assessed using the Mini-Mental State Examination, Dementia Mood Assessment Scale, and Dementia Behavior Disturbance scale. Results Significant decreases in systolic (P steam foot spas. A significant improvement was seen in the Mini-Mental State Examination score (P steam foot baths. In this study, a control group was not used. Raters and enforcers were not blinded. Conclusion The results of this pilot study suggest that steam foot spas mitigate cognitive impairment in geriatric inpatients. PMID:23717038

  19. Clinical researches on the efficacy of spa therapy in fibromyalgia: a systematic review

    Directory of Open Access Journals (Sweden)

    Antonio Fraioli

    2013-06-01

    Full Text Available BACKGROUND: Fibromyalgia is characterized by chronic widespread pain, tenderness at muscle and tendon insertions point when digital pressure is applied, sleep disorders, chronic fatigue, depressive episodes, anxiety, and other functional somatic syndromes. OBJECTIVE: The aim of this study was to determine whether balneotherapy with mineral waters and mineral-water containing mud is effective in the management of fibromyalgia. METHODS: We conducted a systematic review of the literature regarding spa therapy in the treatment of the fibromyalgia. We searched many databases for articles published between 2000 and 2012 and we selected 7 studies among 65 articles retrieved. A total of 142 patients received balneotherapy and 129 were controls. CONCLUSIONS: Study data confirms that spa therapy could improve the symptoms of fibromyalgia including pain, depression and minor symptoms.

  20. Local and spa fee on the example of Kujawsko-pomorskie municipalities

    Directory of Open Access Journals (Sweden)

    Robert Kwaśniewski

    2016-12-01

    Full Text Available The article discusses facultative public levies in the Polish tax system – ie. local and spa tax. This publication presents legal structure of both taxes in accordance with the regulations of local taxes and fees contained in the Act of 12 January 1991. It also presents the results of empirical researches that have been carried out in Kujawsko-pomorskie municipalities, where local and spa taxes occured. The basic aim of study was to determine in which municipalities these fees were in force in 2010–2014 and what income had the individual municipal governments. Completed research would answer the question, whether the analysed charges are effective from local government`s point of view. The article is based on the analysis of legal acts, available literature and using case law of administrative courts. Furthermore, the authors presented the results of empirical research taken from Ms. Iwona Majewska thesis.

  1. [Certain medico-economic prerequisites for the integration of spa and resort facilities into the system of compulsory health insurance].

    Science.gov (United States)

    Artem'eva, G B; Gekht, I A

    2013-01-01

    The involvement of spa and resort facilities in the system of compulsory health insurance is of primary importance for the improvement of medical aid provided to the population. The application of the methods for the calculation of differential expenditures on the spa and resort-based treatment and estimation of their dependence on a variety of factors may facilitate the more rational use of the available resources of compulsory health insurance.

  2. [The psychological security in the framework of the system of factors responsible for the effectiveness of spa and health resort-based rehabilitation].

    Science.gov (United States)

    Krasnyanskaya, T M; Tylets, V G

    The present work was designed to address the problem of ensuring the psychological security in the framework of organization of the rehabilitative treatment based at the spa and health resort facilities. We undertook the questionnaire study for which 650 subjects were recruited among those attending spa and health resort facilities of the cities of Essentuki and Kislovodsk. The participants were asked to estimate the level of their personal security and the quality of the provided means for the rehabilitative treatment and general health improvement. It was found that as many as 43% of the respondents reported the moderate level of psychological security whereas about 30% of them estimated the level of their psychological security as low. Overall, the attitude toward the available means for health improvement and rehabilitation proved extremely variable. The factorial analysis has demonstrated the highly subjective opinions of the responders as regards the provided services categorized in terms of therapeutic (mineral water, preformed physical factors, peloid and dietary therapy), health improvement (herbal medicine, therapeutic physical training, therapy, bioclimatic therapy), and recreational (animation, excursion and touristic activities) factors. The value of these factors was perceived differently by the vacationers with different feelings of psychological security. Those reporting the high level of psychological security demonstrated the positive attitude toward all factors and circumstances available for the general improvement of the health status whereas the holidaymakers reporting the moderate level of personal psychological security exhibited the non-equivalent attitude toward the provided services; namely, they highly estimated the available therapeutic factors but either underestimated the value of the constituent components of the health improving and recreational factors or demonstrated the very selective attitude toward their assessment. Generally

  3. Tourism of Krapinske Toplice Spa - present position and possibilities of Its development

    Directory of Open Access Journals (Sweden)

    Martina Jakovčić

    2003-01-01

    Full Text Available This paper presents present state of development of tourism in Krapinske Toplice Spa and possibilities of further development from the geographical point of view. Natural, socio-economical, cultural and historical components of the area are analysed. Special attention is given to development of health tourism and its impact on the development of other types of tourism. Paper explains the main reason of slower tourist development of Krapinske Toplice in comparison to other spas in the region.

  4. DNAGear- a free software for spa type identification in Staphylococcus aureus

    Science.gov (United States)

    2012-01-01

    Background Staphylococcus aureus is both human commensal and an important human pathogen, responsible for community-acquired and nosocomial infections ranging from superficial wound infections to invasive infections, such as osteomyelitis, bacteremia and endocarditis, pneumonia or toxin shock syndrome with a mortality rate up to 40%. S. aureus reveals a high genetic polymorphism and detecting the genotypes is extremely useful to manage and prevent possible outbreaks and to understand the route of infection. One of current and expanded typing method is based on the X region of the spa gene composed of a succession of repeats of 21 to 27 bp. More than 10000 types are known. Extracting the repeats is impossible by hand and needs a dedicated software. Unfortunately the only software on the market is a commercial program from Ridom. Findings This article presents DNAGear, a free and open source software with a user friendly interface written all in Java on top of NetBeans Platform to perform spa typing, detecting new repeats and new spa types and synchronizing automatically the files with the open access database. The installation is easy and the application is platform independent. In fact, the SPA identification is a formal regular expression matching problem and the results are 100% exact. As the program is using Java embedded modules written over string manipulation of well established algorithms, the exactitude of the solution is perfectly established. Conclusions DNAGear is able to identify the types of the S. aureus sequences and detect both new types and repeats. Comparing to manual processing, which is time consuming and error prone, this application saves a lot of time and effort and gives very reliable results. Additionally, the users do not need to prepare the forward-reverse sequences manually, or even by using additional tools. They can simply create them in DNAGear and perform the typing task. In short, researchers who do not have commercial software will

  5. DNAGear--a free software for spa type identification in Staphylococcus aureus.

    Science.gov (United States)

    AL-Tam, Faroq; Brunel, Anne-Sophie; Bouzinbi, Nicolas; Corne, Philippe; Bañuls, Anne-Laure; Shahbazkia, Hamid Reza

    2012-11-19

    Staphylococcus aureus is both human commensal and an important human pathogen, responsible for community-acquired and nosocomial infections ranging from superficial wound infections to invasive infections, such as osteomyelitis, bacteremia and endocarditis, pneumonia or toxin shock syndrome with a mortality rate up to 40%. S. aureus reveals a high genetic polymorphism and detecting the genotypes is extremely useful to manage and prevent possible outbreaks and to understand the route of infection. One of current and expanded typing method is based on the X region of the spa gene composed of a succession of repeats of 21 to 27 bp. More than 10000 types are known. Extracting the repeats is impossible by hand and needs a dedicated software. Unfortunately the only software on the market is a commercial program from Ridom. This article presents DNAGear, a free and open source software with a user friendly interface written all in Java on top of NetBeans Platform to perform spa typing, detecting new repeats and new spa types and synchronizing automatically the files with the open access database. The installation is easy and the application is platform independent. In fact, the SPA identification is a formal regular expression matching problem and the results are 100% exact. As the program is using Java embedded modules written over string manipulation of well established algorithms, the exactitude of the solution is perfectly established. DNAGear is able to identify the types of the S. aureus sequences and detect both new types and repeats. Comparing to manual processing, which is time consuming and error prone, this application saves a lot of time and effort and gives very reliable results. Additionally, the users do not need to prepare the forward-reverse sequences manually, or even by using additional tools. They can simply create them in DNAGear and perform the typing task. In short, researchers who do not have commercial software will benefit a lot from this

  6. [Sanatorium-and-spa treatment of children with mucoviscidosis and pancreatic lesions].

    Science.gov (United States)

    Mesropian, S K; Kaĭsinova, A S; Stanilevich, T B; Ter-Akopov, N G

    2010-01-01

    Over 5 years ago, the Yunost' sanatorium, Essentuki, and the Russian Centre of Mucoviscidosis, Moscow, began to jointly implement a rehabilitation program for children with mucoviscidosis. The data obtained made it possible for the first time to propose incorporation of drinking carbonate mineral water in the combined sanatorium-and-spa treatment of such patients. The new method allowed effectiveness of this therapy to be improved by 16-18%.

  7. Pulling Marbles from a Bag: Deducing the Regional Impact History of the SPA Basin from Impact Melt Rocks

    Science.gov (United States)

    Cohen, Barbara A.; Coker, R. F.

    2009-01-01

    The South Pole-Aitken (SPA) basin is an important target for absolute age-dating. Vertical and lateral impact mixing ensures that regolith within SPA will contain rock fragments from SPA itself, local impact craters, and faraway giant basins. About 20% of the regolith at any given site is foreign [1, 2], but much of this material will be cold ejecta, not impact melt. We calculated the fraction of contributed impact melt using scaling laws to estimate the amount and provenance of impact melt, demonstrating that SPA melt is the dominant impact melt rock (>70%) likely to be present. We also constructed a statistical model to illustrate how many randomly-selected impact-melt fragments would need to be dated, and with what accuracy, to confidently reproduce the impact history of a site. A detailed impact history becomes recognizable after a few hundred to a thousand randomly-selected marbles, however, it will be useful to have more information (e.g. compositional, mineralogical, remote sensing) to group fragments. These exercises show that SPA melt has a high probability of being present in a scoop sample and that dating of a few hundred to a thousand impact-melt fragments will yield the impact history of the SPA basin.

  8. Spa therapy and balneotherapy for treating low back pain: meta-analysis of randomized trials.

    Science.gov (United States)

    Pittler, M H; Karagülle, M Z; Karagülle, M; Ernst, E

    2006-07-01

    Low back pain is a major public health concern and complementary treatments are frequently used for this condition. The objective of this systematic review and meta-analysis was to assess the evidence for or against the effectiveness of spa therapy and balneotherapy for treating low back pain. Systematic searches were conducted on Medline, Embase, Amed Cochrane Central, the UK National Research Register and ClincalTrials.gov (all until July 2005). Hand searches were performed and experts contacted. Methodological quality was assessed using a standard scale. Five randomized clinical trials met all inclusion criteria. Quantitative data synthesis was performed. The data for spa therapy, assessed on a 100 mm visual analogue scale (VAS), suggest significant beneficial effects compared with waiting list control groups (weighted mean difference 26.6 mm, 95% confidence interval 20.4-32.8, n=442) for patients with chronic low back pain. For balneotherapy the data, assessed on a 100 mm VAS, also suggest beneficial effects compared with control groups (weighted mean difference 18.8 mm, 95% confidence interval 10.3-27.3, n=138). Even though the data are scarce, there is encouraging evidence suggesting that spa therapy and balneotherapy may be effective for treating patients with low back pain. These data are not compelling but warrant rigorous large-scale trials.

  9. Determination of protective properties of Bardejovske Kuple spa curative waters by rotational viscometry and ABTS assay

    Directory of Open Access Journals (Sweden)

    TOPOLSKA Dominika

    2014-02-01

    Full Text Available Mineral waters from Bardejovske Kupele spa are natural, strongly mineralized, with healing effects. They are classified as hydrocarbonic - containing chloride and sodium - carbonic, cold, hypotonic, with a relatively high boric acid content. Potential anti-oxidative effects of curative waters from Bardejovske Kupele were investigated against the hyaluronan (HA degradation. High-molar-mass HA was exposed to the action of ascorbate and cupric ions, which initiate free-radical chain degradation. Time-dependent changes of dynamic viscosity (h of the HA solutions were monitored by rotational viscometry. The radical scavenging capacity of curative waters was determined by the ABTS assay. Despite a significantly high content of transition metal ions, especially iron, remarkable protective effects of the two curative spa waters were found, namely Alzbeta and Klara. Even though “Alzbeta´s“ iron content was 3.5-fold higher than “Klara´s“, “Alzbeta“ was shown to have better protective properties against the HA degradation compared to “Klara“. Bolus addition of ferric ions to the reaction system instead of the natural iron-containing curative water caused a significant HA degradation. The ABTS decolorization assay revealed that the curative spa waters were proven as poorly effective scavengers of the ABTS·+ cation radical.

  10. Transmission of Staphylococcus aureus from maternity unit staff members to newborns disclosed through spa typing.

    Science.gov (United States)

    Matussek, Andreas; Taipalensuu, Jan; Einemo, Ing-Marie; Tiefenthal, Malena; Löfgren, Sture

    2007-03-01

    We observed previously that newborn infants are colonized with Staphylococcus aureus, even if their mothers do not carry S aureus. This observation indicated a cross colonization, and, thus, a risk for nosocomial infection, although the infants are roomed in with their mothers. The S aureus colonization of infants, their parents, and staff members was measured at 3 maternity units. Possible transmission routes were determined using spa typing of S aureus isolates. Infants had the highest S aureus carriage (45%) compared with fathers (39%), mothers (27%), and staff members (27%). In 13 out of 44 colonized infants, transmission from staff members was indicated. This transmission was more frequent than was transmission from their own parents (11 cases), and occurred even in cases when parents were colonized with S aureus of other spa types. We confirm a high level of transmission of S aureus from staff members to infants, indicating a risk for patient safety, which necessitates continuing work with implementing scientific evidence for infection control. The spa typing is a rapid and valuable epidemiological tool, and it can be used in improving hospital hygiene control programs.

  11. Task Context Influences Brain Activation during Music Listening

    Directory of Open Access Journals (Sweden)

    Andjela Markovic

    2017-06-01

    Full Text Available In this paper, we examined brain activation in subjects during two music listening conditions: listening while simultaneously rating the musical piece being played [Listening and Rating (LR] and listening to the musical pieces unconstrained [Listening (L]. Using these two conditions, we tested whether the sequence in which the two conditions were fulfilled influenced the brain activation observable during the L condition (LR → L or L → LR. We recorded high-density EEG during the playing of four well-known positively experienced soundtracks in two subject groups. One group started with the L condition and continued with the LR condition (L → LR; the second group performed this experiment in reversed order (LR → L. We computed from the recorded EEG the power for different frequency bands (theta, lower alpha, upper alpha, lower beta, and upper beta. Statistical analysis revealed that the power in all examined frequency bands increased during the L condition but only when the subjects had not had previous experience with the LR condition (i.e., L → LR. For the subjects who began with the LR condition, there were no power increases during the L condition. Thus, the previous experience with the LR condition prevented subjects from developing the particular mental state associated with the typical power increase in all frequency bands. The subjects without previous experience of the LR condition listened to the musical pieces in an unconstrained and undisturbed manner and showed a general power increase in all frequency bands. We interpret the fact that unconstrained music listening was associated with increased power in all examined frequency bands as a neural indicator of a mental state that can best be described as a mind-wandering state during which the subjects are “drawn into” the music.

  12. Activated carbon oxygen content influence on water and surfactant adsorption.

    Science.gov (United States)

    Pendleton, Phillip; Wu, Sophie Hua; Badalyan, Alexander

    2002-02-15

    This research investigates the adsorption properties of three activated carbons (AC) derived from coconut, coal, and wood origin. Each carbon demonstrates different levels of resistance to 2 M NaOH treatment. The coconut AC offers the greatest and wood AC the least resistance. The influence of base treatment is mapped in terms of its effects on specific surface area, micropore volume, water adsorption, and dodecanoic acid adsorption from both water and 2 M NaOH solution. A linear relationship exists between the number of water molecules adsorbed at the B-point of the water adsorption isotherm and the oxygen content determined from elemental analysis. Surfactant adsorption isotherms from water and 2 M NaOH indicate that the AC oxygen content effects a greater dependence on affinity for surfactant than specific surface area and micropore volume. We show a linear relationship between the plateau amount of surfactant adsorbed and the AC oxygen content in both water and NaOH phases. The higher the AC oxygen content, the lower the amount of surfactant adsorbed. In contrast, no obvious relationship could be drawn between the surfactant amount adsorbed and the surface area.

  13. Influence of coal preoxidation on the porosity of the activated carbons with steam activation

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Yuwen; Gao, Jihui; Sun, Fei; Li, Yang; Wu, Shaohua; Qin, Yukun [Harbin Institute of Technology, Harbin (China). School of Energy Science and Engineering

    2013-07-01

    Activated carbons have been prepared from a low ash content anthracite preoxidized in air to different degrees. Steam has been used as activating agent to prepare different burn-off samples. The preoxidation effect on the physico-chemical characteristics of the resulting chars and activated carbons were comparatively studied. The surface area and porosity of sample was studied by N{sub 2} adsorption at 77 0A0;K. The results show that introduced oxygen in coal structure had a great influence on the carbonization and subsequent activation process. The carbonization of oxidized coal exhibited a broader volatile evolution with respect to temperature, and the resulting chars had a larger microporosity. The porosity of the char is a primary foundation to develop more microporosity upon activation. Activation of char from oxidized coal facilitated development of small scale micropore, however, the micropore widening was also observed at high burn-offs. Compared with development of supermicropore, the evolution of mesoporosity is hindered strongly by preoxidation treatment. The quantity of basic surface sites in activated carbons increased with an increase in oxidation degree, while the quantity of acidic sites appeared equivalent. It seemed that the amount of surface groups and the microporosity mainly developed in a parallel way.

  14. Adjusting tourist destination marketing strategy according to the changes in the environment: Case study Bukovicka sSpa

    Directory of Open Access Journals (Sweden)

    Riznić Dejan T.

    2014-01-01

    Full Text Available Tourist destinations are compelled to create new business opportunities constantly in order to respond to the challenges that arise under the influence of a number of changes in the environment. Few of them are supporting the requirements for analyzing and creating a sustainable business and marketing strategies. The paper starts with the analysis of relevant theory and practice in decisionmaking and choosing the marketing strategy of the tourist destination, pointing to the importance of continuous adjustment of marketing strategy in order to improve the business performance and competitive advantage. A new approach to the design and management of market relations, as well as the need for adjusting marketing strategies to the changes in the environment, is presented in the case of Bukovacka Spa. In deciding, great emphasis is placed on the role and importance of innovation in marketing approaches as well as on the need to develop socially responsible marketing in order to improve its business performance and response to changes in the environment and more successfully positioning.

  15. Waste heat utilization in the thermal spa of Lavey-les-Bains; Etude de la valorisation des rejets thermiques des Bains de Lavey

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This final report for the Swiss Federal Office of Energy looks at the possibilities for improved waste water utilization in the Lavey-les-Bains thermal spa, Switzerland. According to the regulations in force, the temperature of the waste water rejected into the Rhone river shall not exceed 30 {sup o}C, what is currently not the case. Also the operational cost shall be reduced and the waste water quality improved. The installations are presented. From the two geothermal wells, mineral water comes out at an average flow rate of 940 l/min and a temperature of 63 {sup o}C. Actual waste water data are reported. The measured thermal water consumption data, including seasonal variations, are analysed by computerized simulation and measures to reduce the consumed volume by the optimization of internal procedures are evaluated. Measures to reduce the quantity of the rejected free chlorine are discussed. Several possible adaptations of the existing space heating, domestic water heating and pools' heating are evaluated, including cost. In addition, extensions of the thermal spa center to recreational activities are discussed, as the construction of a tropical greenhouse is.

  16. Factors influencing suspended solids concentrations in activated sludge settling tanks.

    Science.gov (United States)

    Kim, Y; Pipes, W O

    1999-05-31

    A significant fraction of the total mass of sludge in an activated sludge process may be in the settling tanks if the sludge has a high sludge volume index (SVI) or when a hydraulic overload occurs during a rainstorm. Under those conditions, an accurate estimate of the amount of sludge in the settling tanks is needed in order to calculate the mean cell residence time or to determine the capacity of the settling tanks to store sludge. Determination of the amount of sludge in the settling tanks requires estimation of the average concentration of suspended solids in the layer of sludge (XSB) in the bottom of the settling tanks. A widely used reference recommends averaging the concentrations of suspended solids in the mixed liquor (X) and in the underflow (Xu) from the settling tanks (XSB=0. 5{X+Xu}). This method does not take into consideration other pertinent information available to an operator. This is a report of a field study which had the objective of developing a more accurate method for estimation of the XSB in the bottom of the settling tanks. By correlation analysis, it was found that only 44% of the variation in the measured XSB is related to sum of X and Xu. XSB is also influenced by the SVI, the zone settling velocity at X and the overflow and underflow rates of the settling tanks. The method of averaging X and Xu tends to overestimate the XSB. A new empirical estimation technique for XSB was developed. The estimation technique uses dimensionless ratios; i.e., the ratio of XSB to Xu, the ratio of the overflow rate to the sum of the underflow rate and the initial settling velocity of the mixed liquor and sludge compaction expressed as a ratio (dimensionless SVI). The empirical model is compared with the method of averaging X and Xu for the entire range of sludge depths in the settling tanks and for SVI values between 100 and 300 ml/g. Since the empirical model uses dimensionless ratios, the regression parameters are also dimensionless and the model can be

  17. Argentine influence on regulatory activities in Latin America

    International Nuclear Information System (INIS)

    Palacios, Elias

    1998-01-01

    An analysis of the nuclear regulatory systems and the nuclear regulations of many Latin American countries shows a substantial influence of the Argentine regulatory structure. This influence is attributed to the early Argentine development of a regulatory and control organization, the teaching of regional training courses and the advice of Argentine experts to Latin-American governments

  18. Comparison of the DiversiLab Repetitive Element PCR System with spa Typing and Pulsed-Field Gel Electrophoresis for Clonal Characterization of Methicillin-Resistant Staphylococcus aureus▿

    Science.gov (United States)

    Babouee, B.; Frei, R.; Schultheiss, E.; Widmer, A. F.; Goldenberger, D.

    2011-01-01

    The emergence of methicillin-resistant Staphylococcus aureus (MRSA) has become an increasing problem worldwide in recent decades. Molecular typing methods have been developed to identify clonality of strains and monitor spread of MRSA. We compared a new commercially available DiversiLab (DL) repetitive element PCR system with spa typing, spa clonal cluster analysis, and pulsed-field gel electrophoresis (PFGE) in terms of discriminatory power and concordance. A collection of 106 well-defined MRSA strains from our hospital was analyzed, isolated between 1994 and 2006. In addition, we analyzed 6 USA300 strains collected in our institution. DL typing separated the 106 MRSA isolates in 10 distinct clusters and 8 singleton patterns. Clustering analysis into spa clonal complexes resulted in 3 clusters: spa-CC 067/548, spa-CC 008, and spa-CC 012. The discriminatory powers (Simpson's index of diversity) were 0.982, 0.950, 0.846, and 0.757 for PFGE, spa typing, DL typing, and spa clonal clustering, respectively. DL typing and spa clonal clustering showed the highest concordance, calculated by adjusted Rand's coefficients. The 6 USA300 isolates grouped homogeneously into distinct PFGE and DL clusters, and all belonged to spa type t008 and spa-CC 008. Among the three methods, DL proved to be rapid and easy to perform. DL typing qualifies for initial screening during outbreak investigation. However, compared to PFGE and spa typing, DL typing has limited discriminatory power and therefore should be complemented by more discriminative methods in isolates that share identical DL patterns. PMID:21307215

  19. [Impact of SPA therapy with sulphureous mineral water on quality of life and psychological distress in chronic plaque psoriasis].

    Science.gov (United States)

    Costantino, M; Filippelli, A

    2014-01-01

    The plaque psoriasis, one of the most common form of psoriasis, is a chronic inflammatory disease. This pathology can cause devastating effects on quality of life and social relations with significant physical and psychological distress. Currently among the therapeutic agents available for the treatment of psoriasis is including SPA therapy, whose mechanism of action is only partially known, as well as very few studies examined the impact of this therapy on the quality of life. On the basis of these considerations, the research analyzed the effectiveness of SPA bath therapy (BLT) and its impact on quality of life and psychological distress in patients suffering from chronic plaque psoriasis. The study was conducted on 35 patients with chronic plaque psoriasis: 23% male and 77% female; mean age:56 ± 19 years; age range:17-85 years. The subjects were treated, for 2 weeks, with sulphureous SPA bath therapy from Terme of Telese SpA (Benevento-Italy). At the beginning and at the end of the SPA treatment considered was evaluated: the itching symptom (using NRS scale); the PASI Index; the impact on quality of life (using SF-36 and DLQI questionnaires) and on psychological distress (using ZUNG -tests). At the end of the SPA treatment, the mean values ± SD, compared to baseline, have showed a significant (p 1.0 ± 1.0) and PASI score (4 ± 4-->1.7 ± 2) with an improvement in quality of life and psichological distress as demonstrated by SF-36, DLQI and ZUNG tests. The data of this research show that the sulphureous SPA bath therapy can be considered very useful in patients with mild-to-moderate psoriasis for the improving of the quality of life and social relationship.

  20. Alcohol peer influence of participating in organized school activities: a network approach.

    Science.gov (United States)

    Fujimoto, Kayo; Valente, Thomas W

    2013-10-01

    This study compares the network influences on adolescent substance use from peers who coparticipated in school-sponsored organized activities (affiliation-based peer influence) with the influence both from their "nominated" friends (i.e., the adolescent named the alter as a friend), and only "reciprocated" friends (i.e., both adolescents mutually named each other as friends). The study also attempts to parse affiliation-based peer influence into the influence of both activity members who are also friends and those who are not, to address the potential confounding of these sources of peer influence. The study data consisted of a nationally representative sample of 12,551 adolescents in Grades 7-12 within 106 schools from the Add Health data. Ordinal logistic regression was conducted to estimate the effects of affiliation-based and friends influence on alcohol use and drinking frequency. Peer influence via organized activities (sports or clubs) with drinkers and the influence of friends who drink had significant effects on adolescent drinking. Peer influence through club activities with drinkers had a stronger effect on any drinking behavior than through sports activities with drinkers. After decomposing peer influence through activities by friendship status, influence through sport activities had a significant effect on drinking only when coparticipant drinkers were also reciprocated friends (but not nominated friends), whereas influence through club activities had a significant effect on drinking, regardless of friendship reciprocation. The design and implementation of school based substance use prevention and treatment programs should consider the contextual effects of school-sponsored activities. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  1. Noise level arrangement in determined zones of homogenous development of green areas on the example of the spa park in Inowrocław

    Science.gov (United States)

    Sztubecka, Małgorzata; Skiba, Marta

    2016-11-01

    Noise measurements are usually carried out in developed areas as well as in the surroundings of traffic routes providing basis for actions in order to limit its influence on the neighboring areas. Noise measurements in park areas are rare due to belief that these areas are silent zones. Such attitude cannot be justified. This article aims to the assessment of noise appearing in determined subzones of the spa park in Inowrocław. From the research carried out it can be noticed that traffic noise does not have any important meaning for the acoustic climate of the park. It is the people who stay there who generate more noise. Comparative analysis proves the appearance and penetration of noise from the zones with greater level of noise to the ones with lower amount.

  2. The influence of leisure-time physical activity and lifestyle on a ...

    African Journals Online (AJOL)

    The influence of leisure-time physical activity and lifestyle on a coronary risk index ... African Journal for Physical Activity and Health Sciences ... from mid- and top management level from companies in South Africa participated in this survey.

  3. A grounded theory of how social support influences physical activity in adolescent girls

    Science.gov (United States)

    Fawkner, Samantha

    2018-01-01

    ABSTRACT Purpose: Adolescent girls are not sufficiently active to achieve health benefits. Social support from friends and family has been positively associated with physical activity in adolescent girls; however it is unclear how social support influences physical activity behaviour. This study aimed to develop a grounded theory of how social support influences physical activity in adolescent girls. Methods: A qualitative, constructivist grounded theory approach was adopted. Individual interviews explored adolescent girls’ perspectives of how significant others’ influenced their physical activity through providing social support, and through modelling physical activity. Results: Participants perceived social support to influence physical activity behaviour through performance improvements, self-efficacy, enjoyment, motivation and by enabling physical activity. Improvements in performance and self-efficacy were also linked to motivation to be active. Girls perceived modelling to influence behaviour through providing opportunities for them to be physically active, and by inspiring them to be active. Conclusion: The grounded theory outlines adolescent girls’ perceptions of how significant others influence their physical activity and provides a framework for future research examining the role of social support on physical activity. PMID:29405881

  4. A grounded theory of how social support influences physical activity in adolescent girls.

    Science.gov (United States)

    Laird, Yvonne; Fawkner, Samantha; Niven, Ailsa

    2018-12-01

    Adolescent girls are not sufficiently active to achieve health benefits. Social support from friends and family has been positively associated with physical activity in adolescent girls; however it is unclear how social support influences physical activity behaviour. This study aimed to develop a grounded theory of how social support influences physical activity in adolescent girls. A qualitative, constructivist grounded theory approach was adopted. Individual interviews explored adolescent girls' perspectives of how significant others' influenced their physical activity through providing social support, and through modelling physical activity. Participants perceived social support to influence physical activity behaviour through performance improvements, self-efficacy, enjoyment, motivation and by enabling physical activity. Improvements in performance and self-efficacy were also linked to motivation to be active. Girls perceived modelling to influence behaviour through providing opportunities for them to be physically active, and by inspiring them to be active. The grounded theory outlines adolescent girls' perceptions of how significant others influence their physical activity and provides a framework for future research examining the role of social support on physical activity.

  5. Chemical composition of the thermomineral waters of Josanicka Banja spa as an origin indicator, balneological valorization and geothermal potential

    Directory of Open Access Journals (Sweden)

    Milenić Dejan R.

    2015-01-01

    Full Text Available The chemical composition of the groundwater is directly dependent on the geological structure, hydrogeological and hydrochemical characteristics and as such it represents an output result of all the factors and processes which take place in the environment within which they were formed. The chemical composition of thermomineral waters often represents a crucial factor in determining the origin, balneological valorization and geothermal potential of the resources. This work presents the analysis of origin, belneological valorization and geothermal potential of Josanicka Banja spa, on the basis of the results gained through making the analyisis of chemical contents of the thermomineral waters which occur in the area. The ratio of concentrations of specific chemical components in the thermomineral waters of Josanicka Banja has served as the basic tool for ascertaining the origin of these waters. On the basis of the analysis of the main anion-cation and gas compositions as well as the contents of specific micro-components, a balneological valorization of these resources has been carried out. Apart from that this work also presents the calculation of the expected temperatures in the primary geothermal reservoir, which was carried out on the basis of the results of chemical analysis of thermomineral waters that occur in the area. Geothermal potential of about 4 MWt and significant contents of balneologically active components of the chemical composition of these waters, open up a possibility for their multi-purpose use, which is also presented in the work. [Projekat Ministarstva nauke Republike Srbije, br. TR 33053

  6. The Role of Aspiration Level in Risky Choice: A Comparison of Cumulative Prospect Theory and SP/A Theory.

    Science.gov (United States)

    Lopes; Oden

    1999-06-01

    In recent years, descriptive models of risky choice have incorporated features that reflect the importance of particular outcome values in choice. Cumulative prospect theory (CPT) does this by inserting a reference point in the utility function. SP/A (security-potential/aspiration) theory uses aspiration level as a second criterion in the choice process. Experiment 1 compares the ability of the CPT and SP/A models to account for the same within-subjects data set and finds in favor of SP/A. Experiment 2 replicates the main finding of Experiment 1 in a between-subjects design. The final discussion brackets the SP/A result by showing the impact on fit of both decreasing and increasing the number of free parameters. We also suggest how the SP/A approach might be useful in modeling investment decision making in a descriptively more valid way and conclude with comments on the relation between descriptive and normative theories of risky choice. Copyright 1999 Academic Press.

  7. The influence of physical activity on components of metabolic ...

    African Journals Online (AJOL)

    African Journal for Physical Activity and Health Sciences ... Inactivity causes obesity which is related to insulin resistance, hypertension, diabetes mellitus, ... of physical activity (PA) on the MS components and vascular function in children and ...

  8. Effect of a steam foot spa on geriatric inpatients with cognitive impairment: a pilot study

    Directory of Open Access Journals (Sweden)

    Koike Y

    2013-05-01

    Full Text Available Yoshihisa Koike,1 Hideki Kondo,2 Satoshi Kondo,1 Masayuki Takagi,1 Yoshio Kano31Department of Occupational Therapy, Prefectural University of Hiroshima, Mihara, Japan; 2Yoshiigawa Hospital, Okayama, Japan; 3Department of Occupational Therapy, Kibi International University, Takahashi, JapanPurpose: To investigate whether a steam foot spa improves cognitive impairment in geriatric inpatients.Methods: Geriatric inpatients with cognitive impairment were given a steam foot spa treatment at 42°C for 20 minutes for 2 weeks (5 days/week. Physiological indicators such as blood pressure, percutaneous oxygen saturation, pulse, tympanic temperature, and sleep time and efficiency were assessed. Cognitive function and behavioral and psychological symptoms of dementia were assessed using the Mini-Mental State Examination, Dementia Mood Assessment Scale, and Dementia Behavior Disturbance scale.Results: Significant decreases in systolic (P < 0.01 and diastolic blood pressure (P < 0.05 along with a significant increase in tympanic temperature (P < 0.01 were observed after the steam foot spas. A significant improvement was seen in the Mini-Mental State Examination score (P < 0.01 and the overall dementia severity items in Dementia Mood Assessment Scale (P < 0.05.Limitations: Japanese people are very fond of foot baths. However, it is difficult to understand why inpatients cannot receive steam foot baths. In this study, a control group was not used. Raters and enforcers were not blinded.Conclusion: The results of this pilot study suggest that steam foot spas mitigate cognitive impairment in geriatric inpatients.Keywords: steam foot spa, geriatric inpatients, cognitive impairment, tympanic temperature

  9. Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis.

    Science.gov (United States)

    Golusin, Zoran; Jovanović, Marina; Magda, Natasa; Stojanović, Slobodan; Matić, Milan; Petrović, Aleksandra

    2015-11-01

    Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue), balneotherapy is drawing increased attention worldwide. Being part of climatotherapy, balneotherapy is defined as the use of natural environmental factors in the treatment of health conditions, whereas in the treatment of psoriasis it means the use of mineral baths and peloids. The aim of this study was to examine the therapeutic efficacy of mineral waters and peloids of the Rusanda Spa on plaque psoriasis in patients also treated with calcipotriol. The study included 60 patients divided into two groups. The first group included patients treated with mineral waters, peloids and calcipotriol in the Rusanda Spa, while the second one included those treated only with calcipotriol. The study took 21 days, and each patient was followed up for at least one month after ending the treatment. The treatment efficacy was measured by psoriasis area severity index (PASI) scores on the days 0, 7, 14 and 21 during the treatment and 30 after the end of the therapy. After a 3-week treatment in the Rusanda Spa, the first group showed a decrease in PASI score by 59.45%, whereas in the group of outpatients treated by calcipotriol it was 39.34%. On the day 30 following the treatment, the first group presented with the PASI score reduction of 58.44%, and the second group of 34.78%. The therapeutic efficacy of mineral waters and peloids combined with calcipotriol showed to be significantly higher in regard to monotherapy with calcipotriol (p balneotherapy as monotherapy in treatment of this type of psoriasis.

  10. Performance of scintillation proximity assay (SPA) to measure the level of VEGFR 1 protein

    International Nuclear Information System (INIS)

    LEE, So-Young; LIM, Jae-Cheong; KIM, Jin-Joo

    2014-01-01

    Scintillation proximity assay is a one of radioimmunoassay and can be assayed without the washing or filtration procedures normally used to separate bound from free fractions. Due to its simplicity and high-throughput protocol, it is broadly applicable to immunology, receptor binding, monitoring receptor-ligand interactions and enzyme reactions. Briefly, an antibody or receptor is coated on SPA beads. When a radiolabeled antigen or ligand binds to the beads, the SPA beads stimulate to emit short range electrons. The 3 H and 125 I are commonly used for radiolabeling and the produced photons are detectable with a liquid scintillation counter (LSC). A binding affinity of unlabeled ligands can be determined by competitive reaction of the radiolabeled ligands. Bevacizumab is a recombinant humanized monoclonal antibody, and can stop or delay growth of tumors by inhibiting vascular endothelial growth factor (VEGF). Bevacizumab was approved by FDA for metastatic cancer such as colorectal cancers, ovarian cancers, breast cancers and glioblastoma multiform of the brain. Recently, Dan G. duda et al. was reported that the concentration of vascular endothelial growth factor receptor-1 (VEGFR-1) in plasma may potentially be used as a negative selection biomarker. In this study, we describe a method using scintillation proximity assay to detect the amounts of VEGFR-1 protein. This method is successfully used to measure the concentration of VEGFR-1 protein in human cell extracts. In summary, a simple and sensitive assay is developed for measuring the amount of VEGFR 1 protein in cancer cell lysate using SPA beads. The antibody coating on the beads and antigen binding are achieved in one mixing step

  11. Performance of scintillation proximity assay (SPA) to measure the level of VEGFR 1 protein

    Energy Technology Data Exchange (ETDEWEB)

    LEE, So-Young; LIM, Jae-Cheong; KIM, Jin-Joo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    Scintillation proximity assay is a one of radioimmunoassay and can be assayed without the washing or filtration procedures normally used to separate bound from free fractions. Due to its simplicity and high-throughput protocol, it is broadly applicable to immunology, receptor binding, monitoring receptor-ligand interactions and enzyme reactions. Briefly, an antibody or receptor is coated on SPA beads. When a radiolabeled antigen or ligand binds to the beads, the SPA beads stimulate to emit short range electrons. The {sup 3}H and {sup 125}I are commonly used for radiolabeling and the produced photons are detectable with a liquid scintillation counter (LSC). A binding affinity of unlabeled ligands can be determined by competitive reaction of the radiolabeled ligands. Bevacizumab is a recombinant humanized monoclonal antibody, and can stop or delay growth of tumors by inhibiting vascular endothelial growth factor (VEGF). Bevacizumab was approved by FDA for metastatic cancer such as colorectal cancers, ovarian cancers, breast cancers and glioblastoma multiform of the brain. Recently, Dan G. duda et al. was reported that the concentration of vascular endothelial growth factor receptor-1 (VEGFR-1) in plasma may potentially be used as a negative selection biomarker. In this study, we describe a method using scintillation proximity assay to detect the amounts of VEGFR-1 protein. This method is successfully used to measure the concentration of VEGFR-1 protein in human cell extracts. In summary, a simple and sensitive assay is developed for measuring the amount of VEGFR 1 protein in cancer cell lysate using SPA beads. The antibody coating on the beads and antigen binding are achieved in one mixing step.

  12. [The toxic complications of hydrogen sulfide-based balneotherapy in the spa and health resort practice].

    Science.gov (United States)

    Khodasevich, L S

    2015-01-01

    The present literature review was designed to consider the toxic complications of hydrogen sulfide-based balneotherapy encountered in the spa and health resort practice that should actually be regarded as hydrogen sulfide intoxication taking into consideration that their severity depends on the route through which the toxicant enters the body, its concentration in the therapeutic bath, and the overall duration of balneotherapy. Although such complications rarely occur in everyday practice, they may constitute a threat to the patient's health which implies the necessity of adequate measures for their prevention.

  13. Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis

    Directory of Open Access Journals (Sweden)

    Golušin Zoran

    2015-01-01

    Full Text Available Background/Aim. Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue, balneotherapy is drawing increased attention worldwide. Being part of climatotherapy, balneotherapy is defined as the use of natural environmental factors in the treatment of health conditions, whereas in the treatment of psoriasis it means the use of mineral baths and peloids. The aim of this study was to examine the therapeutic efficacy of mineral waters and peloids of the Rusanda Spa on plaque psoriasis in patients also treated with calcipotriol. Methods. The study included 60 patients divided into two groups. The first group included patients treated with mineral waters, peloids and calcipotriol in the Rusanda Spa, while the second one included those treated only with calcipotriol. The study took 21 days, and each patient was followed up for at least one month after ending the treatment. The treatment efficacy was measured by psoriasis area severity index (PASI scores on the days 0, 7, 14 and 21 during the treatment and 30 after the end of the therapy. Results. After a 3-week treatment in the Rusanda Spa, the first group showed a decrease in PASI score by 59.45%, whereas in the group of outpatients treated by calcipotriol it was 39.34%. On the day 30 following the treatment, the first group presented with the PASI score reduction of 58.44%, and the second group of 34.78%. The therapeutic efficacy of mineral waters and peloids combined with calcipotriol showed to be significantly higher in regard to monotherapy with calcipotriol (p < 0.05. In regard to clinical symptoms, the best results were obtained in the reduction of desquamation (p < 0.001. Conclusion. The results of our study show that in the treatment of plaque-type psoriasis, topical calcipotriol combined with Spa Rusanda balneotherapy is more effective than topical

  14. Binding of human collectins (SP-A and MBP) to influenza virus.

    OpenAIRE

    Malhotra, R; Haurum, J S; Thiel, S; Sim, R B

    1994-01-01

    Collectins are a group of soluble proteins each of which has collagenous domains and non-collagenous globular domains, the latter containing the consensus residues found in C-type lectins. Members of the collectin family are the serum proteins mannan-binding protein (MBP), conglutinin, CL-43, and the lung-associated proteins surfactant protein A (SP-A) and surfactant protein D (SP-D). MBP and conglutinin have been shown previously to bind to influenza viruses and to inhibit the infectivity an...

  15. Theories and contemporary challenges of a global pasta leader: the case of Barilla SpA

    OpenAIRE

    Wolf, Ronald Scott

    2015-01-01

    Barilla Holding SpA (Barilla), a successful multinational foods manufacturing company with headquarters in Parma, Italy began with humble beginnings in 1877 (Barilla, 2014a) as a small bread and pasta shop -- Barilla is now a leading global sales player second only to private label brands, jumping from 9-12% of total market from the period 2009-2014 and is the dominant sales leader in both Italy and the US with 2014 sales of 900 and 800 US$ million respectively (Euromonitor, 2015) -- This pap...

  16. Association between Hypothesized Parental Influences and Preschool Children's Physical Activity Behavior

    Science.gov (United States)

    Loprinzi, Paul D.; Schary, David P.; Beets, Michael W.; Leary, Janie; Cardinal, Bradley J.

    2013-01-01

    Background: To date, most research investigating the influence of parents on children"s physical activity behavior has been conducted among school-aged children. As a result, we have a limited understanding of the mechanisms through which parents can influence their young children's physical activity behavior. The purpose of this study was to…

  17. Family Influence on Teenage Participation in School Activities.

    Science.gov (United States)

    Cashion, Barbara G.; Dager, Edward Z.

    This paper is concerned with the relationship between social participation and family structure. A theory is developed in the framework of George Herbert Mead's analysis on the development of a consistent self in response to a generalized other. According to this theory, the influence of the family is implicated as one of the social-psychological…

  18. Activity limitations and factors influencing functional outcome of ...

    African Journals Online (AJOL)

    EB

    2013-09-03

    Sep 3, 2013 ... life and satisfaction with life1,22. A recent study conducted among community dwelling stroke survivors found functional ability and independence to be the strongest predictor of, and were responsible for the greatest variance on participation22. For determining the factors influencing outcome with the use ...

  19. Influence of terbutaline on natural killer cell activity

    International Nuclear Information System (INIS)

    Stenius-Aarniala, B.; Vesterinen, E.; Kiviranta, K.; Timonen, T.

    1988-01-01

    Studies on the effect of cAMO-inducing agents on NK activity have been contradictory. The aim of this study was to investigate the acute effects of beta-agonists on NK activity in vivo in 15 asthmatics and 3 healthy volunteers. Blood samples of NK activity were taken at regular intervals after placebo and after subcutaneous injection of 7 μg/kg of terbutaline. NK activity was measured by the standard 4-h Chromium 51 release assay against the leukemic line K 562 at a 50:1 effector/target cell ratio. Compared with placebo, terbutaline induced within 30-60 min a significant increase in NK activity which lasted less than 2 h. Further studies are necessary to investigate the effect of long-term beta-agonist treatment on NK activity. (author)

  20. Influence of long-term fertilization on soil enzyme activities

    Directory of Open Access Journals (Sweden)

    Alina Dora SAMUEL

    2009-05-01

    Full Text Available Soil enzyme activities (actual and potential dehydrogenase, catalase, acid and alkaline phosphatase were determined in the 0–10, 10–20, and 20–30 cm layers of a brown luvic soil submitted to a complex fertilization experiment with different types of green manure. It was found that each activity decreased with increasing sampling depth. It should be emphasized that greenmanuring of maize led to a significant increase in each of the five enzymatic activities determined. The enzymatic indicators of soil quality calculated from the values of enzymatic activities showed the order: lupinus + rape + oat > lupinus > vetch + oat + ryegrass > lupinus + oat + vetch > unfertilized plot. This order means that by determination of enzymatic activities valuable information can be obtained regarding fertility status of soils. There were significant correlations of soil enzyme activities with chemical properties.

  1. Influence of 2. 45 GHz microwave radiation on enzyme activity

    Energy Technology Data Exchange (ETDEWEB)

    Galvin, M J; Parks, D L; McRee, D I

    1981-05-01

    The in vitro activity of acetylcholinesterase and creatine phosphokinase was determined during in vitro exposure to 2.45 GHz microwave radiation. The enzyme activities were examined during exposure to microwave radiation at specific absorption rates (SAR) of 1, 10, 50, and 100 mW/g. These specific absorption rates had no effect on the activity of either enzyme when the temperature of the control and exposed samples were similar. These data demonstrate that the activity of these two enzymes is not affected by microwave radiation at the SARs and frequency employed in this study.

  2. Pulling Marbles from a Bag: Deducing the Regional Impact History of the SPA Basin from Impact-Melt Rocks

    Science.gov (United States)

    Cohen, Barbara A.; Coker, Robert F.

    2010-01-01

    The South Pole Aitken (SPA) basin is the stratigraphically oldest identifiable lunar basin and is therefore one of the most important targets for absolute age-dating to help understand whether ancient lunar bombardment history smoothly declined or was punctuated by a cataclysm. A feasible near-term approach to this problem is to robotically collect a sample from near the center of the basin, where vertical and lateral mixing provided by post-basin impacts ensures that such a sample will be composed of small rock fragments from SPA itself, from local impact craters, and from faraway giant basins. The range of ages, intermediate spikes in the age distribution, and the oldest ages are all part of the definition of the absolute age and impact history recorded within the SPA basin.

  3. Takeover Activity in Australia: endogenous and exogenous influences

    NARCIS (Netherlands)

    Finn, F.; Hodgson, A.

    2005-01-01

    The present paper analyses the population of takeover bids for listed Australian companies using quarterly data over a 25-year period to re-examine the predictability of takeover activity and to determine if there is a flow on impact on macroeconomic variables. We examine whether takeover activity:

  4. Activity-Driven Influence Maximization in Social Networks

    DEFF Research Database (Denmark)

    Kumar, Rohit; Saleem, Muhammad Aamir; Calders, Toon

    2017-01-01

    -driven approach based on the identification of influence propagation patterns. In the first work, we identify so-called information-channels to model potential pathways for information spread, while the second work exploits how users in a location-based social network check in to locations in order to identify...... influential locations. To make our algorithms scalable, approximate versions based on sketching techniques from the data streams domain have been developed. Experiments show that in this way it is possible to efficiently find good seed sets for influence propagation in social networks.......Interaction networks consist of a static graph with a timestamped list of edges over which interaction took place. Examples of interaction networks are social networks whose users interact with each other through messages or location-based social networks where people interact by checking...

  5. Effectiveness of balneotherapy and spa therapy for the treatment of chronic low back pain: a review on latest evidence.

    Science.gov (United States)

    Karagülle, Mine; Karagülle, Müfit Zeki

    2015-02-01

    In most European countries, balneotherapy and spa therapy are widely prescribed by physicians and preferred by European citizens for the treatment of musculoskeletal problems including chronic low back pain (LBP). We aimed to review and evaluate the recent evidence on the effectiveness of balneotherapy and spa therapy for patients with LBP. We comprehensively searched data bases for randomized controlled trials (RCTs) published in English between July 2005 and December 2013. We identified all trials testing balneotherapy or spa therapy for LBP that reported that the sequence of allocation was randomized. We finally included total of eight RCTs: two on balneotherapy and six on spa therapy. All reviewed trials reported that balneotherapy was superior in long term to tap water therapy in relieving pain and improving function and that spa therapy combining balneotherapy with mud pack therapy and/or exercise therapy, physiotherapy, and/or education was effective in the management of low back pain and superior or equally effective to the control treatments in short and long terms. We used Jadad scale to grade the methodological quality. Only three out of total eight had a score of above 3 indicating the good quality. The data from the RCTs indicates that overall evidence on effectiveness of balneotherapy and spa therapy in LBP is encouraging and reflects the consistency of previous evidence. However, the overall quality of trials is generally low. Better quality RCTs (well designed, conducted, and reported) are needed testing short- and long-term effects for relieving chronic back pain and proving broader beneficial effects.

  6. Professionalization influences on Thai family SMEs internationalization activities

    OpenAIRE

    Kotanut, Varitha

    2012-01-01

    Professionalisation is what has occurred in many family businesses. Recently, Thai family SMEs has become more and more internationalised. My dissertation studied how professionalisation influence firms' internationalisation process, including personnel from whom they acquired relevant skills, specific market knowledge, and experiences that enable growth of the company. These personnel may also affect the firm's managerial system. Each firm may change their governance, strategy, and control s...

  7. INFLUENCE OF BIOLOGICALLY ACTIVE SUBSTANCES ON TOMATO YIELD AND QUALITY

    OpenAIRE

    G. I. Yarovoy; V. I. Kuzmenko

    2017-01-01

    The study of influence of growth regulators and biopreparations affecting on decrease of disease development, increase of yield capacity and final product quality was carried out in tomato. It was shown that all preparations were effective in decreasing the process of diseases development and increasing the yield capacity and product quality. The studies were carried out in the experimental fields at the Institute of Vegetables and Melons NAAS, in Ukraine in 2011-2012. The field studies were ...

  8. Principles of bioclimatic architecture applied at the project of spa center at Stara Planina mountain

    Directory of Open Access Journals (Sweden)

    Marić Igor

    2011-01-01

    Full Text Available Application of bioclimatic parameters in the design of tourist objects is an important factor for reducing energy consumption and preserving the environment. It represents the response to constant changing of climate conditions. Given the fact that development of tourism has negative consequences on the environment, it is necessary to examine the way design process can affect the reduction of energy and environmental pollution. This paper analyzes the principles of bioclimatic planning and design of the Spa Center at the Balkan Mountain that is one of the most valuable ecosystems in Serbia. Adaptation to the existing climate change was analyzed on two levels. The first level was urban factors that include analysis of local climate and environment that affect the positioning of the object and preliminary form. The second level was architecture factors with technical and technological solutions that can be achieved through the application of climate and energy responsible designing. Final analyses indicate that the bioclimatic approach is necessary in the initial stage of setting preliminary design for the building, because later it would take more effort to install technology that requires time and the whole process makes much more expensive. The work indicates that the energy needs of optimized Spa center like represented, from the very beginning of planning and designing, can be drastically reduced.

  9. Balneotherapy for atopic dermatitis in children at Comano spa in Trentino, Italy.

    Science.gov (United States)

    Farina, Stefania; Gisondi, Paolo; Zanoni, Mauro; Pace, Manuela; Rizzoli, Laura; Baldo, Ermanno; Girolomoni, Giampiero

    2011-12-01

    No controlled studies have investigated whether balneotherapy is effective in atopic dermatitis (AD). To investigate the efficacy and safety of balneotherapy performed at Comano spa (Trentino, Italy) compared to topical corticosteroids (TCS) in the treatment of AD. This was an open, randomized, clinical trial including 104 children (aged 1-14 years) with mild to moderate AD who were assigned either to balneotherapy (n = 54) or TCS (n = 50) once daily for 2 weeks. AD severity and quality of life were measured using the SCORAD, investigator global assessment (IGA), patients' self global assessment (PSGA), children's dermatology life quality index (CDLQI) and family dermatitis impact questionnaire (FDIQ). Subjective measures were re-evaluated 4 months after the end of therapy. Balneotherapy and TCS resulted in a significant reduction of all parameters at week 2. TCS were more effective than balneotherapy regarding SCORAD (46% ± 7.71 vs 26% ± 9.4, mean ± SD; p balneotherapy compared to those treated with TCS (p Balneotherapy at Comano spa appears to be beneficial in children with mild to moderate AD.

  10. Characterization of Si(112) and In/Si(112) studied by SPA-LEED

    Energy Technology Data Exchange (ETDEWEB)

    Hoecker, Jan; Speckmann, Moritz; Schmidt, Thomas; Falta, Jens [Institute of Solid State Physics, University of Bremen, 28359 Bremen (Germany)

    2010-07-01

    High index surfaces are of strong interest in todays research because of the possibility to grow low dimensional structures. It has for instance already been shown that the adsorption of Ga can induce the formation of 1D metal chains on Si(112) (cf. Snijders et al., PRB 72, 2005). In this work we investigated the clean Si(112) surface and the adsorption of In on Si(112) to establish an analogy to Ga/Si(112) using spot profile analyzing low energy electron diffraction (SPA-LEED). By means of reciprocal space mapping we determined the bare Si(112) surface to be decomposed into alternating (5512) and (111) facets in [1 anti 10] direction with (2 x 1) and (7 x 7) reconstruction, respectively (cf. Baski et al., Surf. Sci. 392, 1997). With SPA-LEED we were able to observe the decreasing intensity of the facet spots in-situ while depositing In on Si(112) and thus reveal the smoothening of the surface due to the deposition of In. At saturation coverage we found a (3.x1) reconstruction, where x is dependent on the deposition temperature and changes from x=7 at 400 C to x=5 at 500 C. This leads us to the assumption that the reconstruction is not incommensurate but a mixture of (3 x 1) and (4 x 1) building blocks, which is very similar to the super structure of Ga on Si(112).

  11. Influence of different anoxic time exposures on active biomass, protozoa and filamentous bacteria in activated sludge.

    Science.gov (United States)

    Rodriguez-Perez, S; Fermoso, F G; Arnaiz, C

    Medium-sized wastewater treatment plants are considered too small to implement anaerobic digestion technologies and too large for extensive treatments. A promising option as a sewage sludge reduction method is the inclusion of anoxic time exposures. In the present study, three different anoxic time exposures of 12, 6 and 4 hours have been studied to reduce sewage sludge production. The best anoxic time exposure was observed under anoxic/oxic cycles of 6 hours, which reduced 29.63% of the biomass production compared with the oxic control conditions. The sludge under different anoxic time exposures, even with a lower active biomass concentration than the oxic control conditions, showed a much higher metabolic activity than the oxic control conditions. Microbiological results suggested that both protozoa density and abundance of filamentous bacteria decrease under anoxic time exposures compared to oxic control conditions. The anoxic time exposures 6/6 showed the highest reduction in both protozoa density, 37.5%, and abundance of filamentous bacteria, 41.1%, in comparison to the oxic control conditions. The groups of crawling ciliates, carnivorous ciliates and filamentous bacteria were highly influenced by the anoxic time exposures. Protozoa density and abundance of filamentous bacteria have been shown as promising bioindicators of biomass production reduction.

  12. Influence of physical activity on vertebral strength during late adolescence.

    Science.gov (United States)

    Junno, Juho-Antti; Paananen, Markus; Karppinen, Jaro; Tammelin, Tuija; Niinimäki, Jaakko; Lammentausta, Eveliina; Niskanen, Markku; Nieminen, Miika T; Järvelin, Marjo-Riitta; Takatalo, Jani; Tervonen, Osmo; Tuukkanen, Juha

    2013-02-01

    Reduced vertebral strength is a clear risk factor for vertebral fractures. Men and women with vertebral fractures often have reduced vertebral size and bone mineral density (BMD). Vertebral strength is controlled by both genetic and developmental factors. Malnutrition and low levels of physical activity are commonly considered to result in reduced bone size during growth. Several studies have also demonstrated the general relationship between BMD and physical activity in the appendicular skeleton. In this study, we wanted to clarify the role of physical activity on vertebral bodies. Vertebral dimensions appear to generally be less pliant than long bones when lifetime changes occur. We wanted to explore the association between physical activity during late adolescence and vertebral strength parameters such as cross-sectional size and BMD. The association between physical activity and vertebral strength was explored by measuring vertebral strength parameters and defining the level of physical activity during adolescence. The study population consisted of 6,928 males and females who, at 15 to 16 and 19 years of age, responded to a mailed questionnaire inquiring about their physical activity. A total of 558 individuals at the mean age of 21 years underwent magnetic resonance imaging (MRI) scans. We measured the dimensions of the fourth lumbar vertebra from the MRI scans of the Northern Finland Birth Cohort 1986 and performed T2* relaxation time mapping, reflective of BMD. Vertebral strength was based on these two parameters. We analyzed the association of physical activity on vertebral strength using the analysis of variance. We observed no association between the level of physical activity during late adolescence and vertebral strength at 21 years. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Radiological impact of a spent fuel disposal in a deep geological granite formation - results of the european spa project

    International Nuclear Information System (INIS)

    Baudoin, P.; Gay, D.; Certes, C.; Serres, C.

    2000-01-01

    The SPA project (Spent fuel disposal Performance Assessment) is the latest of four integrated performance assessment exercises on nuclear waste disposal in geological formations, carried out in the framework of the European Community 'Nuclear Fission' Research Programmes. The SPA project, which was undertaken by ENRESA, GRS, IPSN, NRG, SCK.CEN and VTT between May 1996 and April 1999, was devoted to the study of disposal of spent fuel in various host rock formations (clay, crystalline rocks and salt formation). This project is a direct continuation of the efforts made by the European Community since 1982 to build a common understanding of the methods applicable to deep disposal performance assessment. (authors)

  14. Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review.

    Science.gov (United States)

    Asadollahi, Parisa; Farahani, Narges Nodeh; Mirzaii, Mehdi; Khoramrooz, Seyed Sajjad; van Belkum, Alex; Asadollahi, Khairollah; Dadashi, Masoud; Darban-Sarokhalil, Davood

    2018-01-01

    Background: Staphylococcus aureus , a leading cause of community-acquired and nosocomial infections, remains a major health problem worldwide. Molecular typing methods, such as spa typing, are vital for the control and, when typing can be made more timely, prevention of S. aureus spread around healthcare settings. The current study aims to review the literature to report the most common clinical spa types around the world, which is important for epidemiological surveys and nosocomial infection control policies. Methods: A search via PubMed, Google Scholar, Web of Science, Embase, the Cochrane library, and Scopus was conducted for original articles reporting the most prevalent spa types among S. aureus isolates. The search terms were " Staphylococcus aureus, spa typing ." Results: The most prevalent spa types were t032, t008 and t002 in Europe; t037 and t002 in Asia; t008, t002, and t242 in America; t037, t084, and t064 in Africa; and t020 in Australia. In Europe, all the isolates related to spa type t032 were MRSA. In addition, spa type t037 in Africa and t037and t437 in Australia also consisted exclusively of MRSA isolates. Given the fact that more than 95% of the papers we studied originated in the past decade there was no option to study the dynamics of regional clone emergence. Conclusion: This review documents the presence of the most prevalent spa types in countries, continents and worldwide and shows big local differences in clonal distribution.

  15. Spa therapy together with supervised self-mobilisation improves pain, function and quality of life in patients with chronic shoulder pain: a single-blind randomised controlled trial

    Science.gov (United States)

    Chary-Valckenaere, Isabelle; Loeuille, Damien; Jay, Nicolas; Kohler, François; Tamisier, Jean-Noë; Roques, Christian-François; Boulange, Michel; Gay, Gérard

    2018-02-01

    To determine whether spa therapy has a beneficial effect on pain and disability in patients with chronic shoulder pain, this single-blind randomised controlled clinical trial included patients with chronic shoulder pain due to miscellaneous conditions attending one of four spa centres as outpatients. Patients were randomised into two groups: spa therapy (18 days of standardised treatment combining thermal therapy together with supervised mobilisation in a thermal pool) and controls (spa therapy delayed for 6 months: `immediate versus delayed treatment' paradigm). All patients continued usual treatments during the 6-month follow-up period. The main endpoint was the mean change in the French-Quick DASH (F-QD) score at 6 months. The effect size of spa therapy was calculated, and the proportion of patients reaching minimal clinically important improvement (MCII) was compared. Secondary endpoints were the mean change in SF-36, treatment use and tolerance. One hundred eighty-six patients were included (94 patients as controls, 92 in the spa group) and analysed by intention to treat. At 6 months, the mean change in the F-QD score was statistically significantly greater among spa therapy patients than controls (- 32.6 versus - 8.15%; p impact on SF-36 components but not on drug intake. Spa therapy provided a statistically significant benefit on pain, function and quality of life in patients with chronic shoulder pain after 6 months compared with usual care.

  16. The influence of experimentally induced pain on shoulder muscle activity

    DEFF Research Database (Denmark)

    Diederichsen, L.P.; Winther, A.; Dyhre-Poulsen, P.

    2009-01-01

    muscles. EMG was recorded before pain, during pain and after pain had subsided and pain intensity was continuously scored on a visual analog scale (VAS). During abduction, experimentally induced pain in the supraspinatus muscle caused a significant decrease in activity of the anterior deltoid, upper......-105A degrees) at a speed of approximately 120A degrees/s, controlled by a metronome. During abduction, electromyographic (EMG) activity was recorded by intramuscular wire electrodes inserted in two deeply located shoulder muscles and by surface-electrodes over six superficially located shoulder...... trapezius and the infraspinatus and an increase in activity of lower trapezius and latissimus dorsi muscles. Following subacromial injection a significantly increased muscle activity was seen in the lower trapezius, the serratus anterior and the latissimus dorsi muscles. In conclusion, this study shows...

  17. Influence of In vitro Digestion on Antioxidative Activity of Coconut ...

    African Journals Online (AJOL)

    Conclusion: CMPHs are high value-added antioxidants and possess a potential ..... side chain groups were expected to be exposed, ..... enzymatic digestion on antioxidant activity of coffee ... yam bean seed (Sphenostylis stenocarpa) protein.

  18. Influence of previous participation in physical activity on its ...

    African Journals Online (AJOL)

    ... in physical activity on its perceptions among tertiary institution students. ... which contribute substantially to the global burden of diseases, death and disability. ... transition period when a person goes from high school to College or University.

  19. Influence of phenolic compounds on rumen microbial activity

    International Nuclear Information System (INIS)

    Vitti, D.M.S.S.; Abdalla, A.L.; Silva Filho, J.C.

    1985-01-01

    An 'in vitro' experiment is carried out to examine the effect of tannic acid on rumen microbial activity, due to the toxicity of phenolic acids on many microrganisms. Rumen content is incubated with sodium bicarbonate, glucose and different quantities of tannic acid. 1 μCi of 32 p-labelled phosphate is added and after 6 hours the incorporated activity is measured. (M.A.C.) [pt

  20. Influence of extracellular zinc on M1 microglial activation.

    Science.gov (United States)

    Higashi, Youichirou; Aratake, Takaaki; Shimizu, Shogo; Shimizu, Takahiro; Nakamura, Kumiko; Tsuda, Masayuki; Yawata, Toshio; Ueba, Tetuya; Saito, Motoaki

    2017-02-27

    Extracellular zinc, which is released from hippocampal neurons in response to brain ischaemia, triggers morphological changes in microglia. Under ischaemic conditions, microglia exhibit two opposite activation states (M1 and M2 activation), which may be further regulated by the microenvironment. We examined the role of extracellular zinc on M1 activation of microglia. Pre-treatment of microglia with 30-60 μM ZnCl 2 resulted in dose-dependent increases in interleukin-1 beta (IL-1β), interleukin-6 (IL-6), and tumour necrosis factor-alpha (TNFα) secretion when M1 activation was induced by lipopolysaccharide administration. In contrast, the cell-permeable zinc chelator TPEN, the radical scavenger Trolox, and the P2X7 receptor antagonist A438079 suppressed the effects of zinc pre-treatment on microglia. Furthermore, endogenous zinc release was induced by cerebral ischaemia-reperfusion, resulting in increased expression of IL-1β, IL-6, TNFα, and the microglial M1 surface marker CD16/32, without hippocampal neuronal cell loss, in addition to impairments in object recognition memory. However, these effects were suppressed by the zinc chelator CaEDTA. These findings suggest that extracellular zinc may prime microglia to enhance production of pro-inflammatory cytokines via P2X7 receptor activation followed by reactive oxygen species generation in response to stimuli that trigger M1 activation, and that these inflammatory processes may result in deficits in object recognition memory.

  1. Eco-SpaCE: An object-oriented, spatially explicit model to assess the risk of multiple environmental stressors on terrestrial vertebrate populations

    International Nuclear Information System (INIS)

    Loos, Mark; Ragas, Ad M.J.; Plasmeijer, Rinus; Schipper, Aafke M.; Hendriks, A. Jan

    2010-01-01

    Wildlife organisms are exposed to a combination of chemical, biological and physical stressors. Information about the relative impact of each stressor can support management decisions, e.g., by the allocation of resources to counteract those stressors that cause most harm. The present paper introduces Eco-SpaCE; a novel receptor-oriented cumulative exposure model for wildlife species that includes relevant ecological processes such as spatial habitat variation, food web relations, predation, and life history. A case study is presented in which the predicted mortality due to cadmium contamination is compared with the predicted mortality due to flooding, starvation, and predation for three small mammal species (Wood mouse, Common vole, and European mole) and a predator (Little owl) living in a lowland floodplain along the river Rhine in The Netherlands. Results indicated that cadmium is the principal stressor for European mole and Little owl populations. Wood mouse and Common vole population densities were mainly influenced by flooding and food availability. Their estimated population sizes were consistent with numbers reported in literature. Predictions for cadmium accumulation and flooding stress were in agreement with field data. The large uncertainty around cadmium toxicity for wildlife leads to the conclusion that more species-specific ecotoxicological data is required for more realistic risk assessments. The predictions for starvation were subject to the limited quantitative information on biomass obtainable as food for vertebrates. It is concluded that the modelling approach employed in Eco-SpaCE, combining ecology with ecotoxicology, provides a viable option to explore the relative contribution of contamination to the overall stress in an ecosystem. This can help environmental managers to prioritize management options, and to reduce local risks.

  2. Contralateral delay activity tracks the influence of Gestalt grouping principles on active visual working memory representations.

    Science.gov (United States)

    Peterson, Dwight J; Gözenman, Filiz; Arciniega, Hector; Berryhill, Marian E

    2015-10-01

    Recent studies have demonstrated that factors influencing perception, such as Gestalt grouping cues, can influence the storage of information in visual working memory (VWM). In some cases, stationary cues, such as stimulus similarity, lead to superior VWM performance. However, the neural correlates underlying these benefits to VWM performance remain unclear. One neural index, the contralateral delay activity (CDA), is an event-related potential that shows increased amplitude according to the number of items held in VWM and asymptotes at an individual's VWM capacity limit. Here, we applied the CDA to determine whether previously reported behavioral benefits supplied by similarity, proximity, and uniform connectedness were reflected as a neural savings such that the CDA amplitude was reduced when these cues were present. We implemented VWM change-detection tasks with arrays including similarity and proximity (Experiment 1); uniform connectedness (Experiments 2a and 2b); and similarity/proximity and uniform connectedness (Experiment 3). The results indicated that when there was a behavioral benefit to VWM, this was echoed by a reduction in CDA amplitude, which suggests more efficient processing. However, not all perceptual grouping cues provided a VWM benefit in the same measure (e.g., accuracy) or of the same magnitude. We also found unexpected interactions between cues. We observed a mixed bag of effects, suggesting that these powerful perceptual grouping benefits are not as predictable in VWM. The current findings indicate that when grouping cues produce behavioral benefits, there is a parallel reduction in the neural resources required to maintain grouped items within VWM.

  3. The Interplay of Networking Activities and Internal Knowledge Actions for Subsidiary Influence within MNCs

    DEFF Research Database (Denmark)

    Najafi-Tavani, Zhaleh; Giroud, Axèle; Andersson, Ulf

    2014-01-01

    in the UK. The results indicate that the possession of strategic resources (knowledge or embedded relations) increases subsidiary influence only when the knowledge is transferred back to headquarters. Importantly, the impact of subsidiary-headquarters embeddedness, external embeddedness and knowledge......Knowledge-based and network-based activities are known determinants of foreign subsidiary influence. We demonstrate that the interaction between these factors is essential in understanding how subsidiaries gain influence within an MNC. We test this using data on 184 foreign-owned subsidiaries...... development on influence is mediated by the extent of reverse knowledge transfer. This mediating role sheds new light on the antecedents to subsidiary influence....

  4. The influence of human activity in the Arctic on climate and climate impacts

    Energy Technology Data Exchange (ETDEWEB)

    Huntington, H.P. [23834 The Clearing Dr., Eagle River, AK 99577 (United States); Boyle, M. [Institute for Resources, Environment and Sustainability, University of British Columbia, 2202 Main Mall, Vancouver, BC, V6S 1K4 (Canada); Flowers, G.E. [Department of Earth Sciences, Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6 (Canada); Weatherly, J.W. [Snow and Ice Division, Cold Regions Research and Engineering Laboratory, 72 Lyme Road, Hanover, NH 03755 (United States); Hamilton, L.C. [Department of Sociology, University of New Hampshire, 20 College Road, Durham, NH 03824 (United States); Hinzman, L. [Water and Environment Research Center, University of Alaska Fairbanks, P.O. Box 755860, Fairbanks, AK 99775 (United States); Gerlach, C. [Department of Anthropology, University of Alaska Fairbanks, P.O. Box 757720, Fairbanks, AK 99775 (United States); Zulueta, R. [Department of Biology, Global Change Research Group, San Diego State University, 5500 Campanile Drive, PS-240, San Diego, CA 92182 (United States); Nicolson, C. [Department of Natural Resources Conservation, University of Massachusetts, 160 Holdsworth Way, Amherst, MA , 01003 (United States); Overpeck, J. [Institute for the Study of Planet Earth, University of Arizona, 715 North Park Avenue, 2nd Floor, Tucson, AZ, 85721 (United States)

    2007-05-15

    Human activities in the Arctic are often mentioned as recipients of climate-change impacts. In this paper we consider the more complicated but more likely possibility that human activities themselves can interact with climate or environmental change in ways that either mitigate or exacerbate the human impacts. Although human activities in the Arctic are generally assumed to be modest, our analysis suggests that those activities may have larger influences on the arctic system than previously thought. Moreover, human influences could increase substantially in the near future. First, we illustrate how past human activities in the Arctic have combined with climatic variations to alter biophysical systems upon which fisheries and livestock depend. Second, we describe how current and future human activities could precipitate or affect the timing of major transitions in the arctic system. Past and future analyses both point to ways in which human activities in the Arctic can substantially influence the trajectory of arctic system change.

  5. Spa therapy together with supervised self-mobilisation improves pain, function and quality of life in patients with chronic shoulder pain: a single-blind randomised controlled trial

    Science.gov (United States)

    Chary-Valckenaere, Isabelle; Loeuille, Damien; Jay, Nicolas; Kohler, François; Tamisier, Jean-Noë; Roques, Christian-François; Boulange, Michel; Gay, Gérard

    2018-06-01

    To determine whether spa therapy has a beneficial effect on pain and disability in patients with chronic shoulder pain, this single-blind randomised controlled clinical trial included patients with chronic shoulder pain due to miscellaneous conditions attending one of four spa centres as outpatients. Patients were randomised into two groups: spa therapy (18 days of standardised treatment combining thermal therapy together with supervised mobilisation in a thermal pool) and controls (spa therapy delayed for 6 months: `immediate versus delayed treatment' paradigm). All patients continued usual treatments during the 6-month follow-up period. The main endpoint was the mean change in the French-Quick DASH (F-QD) score at 6 months. The effect size of spa therapy was calculated, and the proportion of patients reaching minimal clinically important improvement (MCII) was compared. Secondary endpoints were the mean change in SF-36, treatment use and tolerance. One hundred eighty-six patients were included (94 patients as controls, 92 in the spa group) and analysed by intention to treat. At 6 months, the mean change in the F-QD score was statistically significantly greater among spa therapy patients than controls (- 32.6 versus - 8.15%; p < 0.001) with an effect size of 1.32 (95%CI: 0.97-1.68). A significantly greater proportion of spa therapy patients reached MCII (59.3 versus 17.9%). Spa therapy was well tolerated with a significant impact on SF-36 components but not on drug intake. Spa therapy provided a statistically significant benefit on pain, function and quality of life in patients with chronic shoulder pain after 6 months compared with usual care.

  6. Triangular relationship between sleep spindle activity, general cognitive ability and the efficiency of declarative learning.

    Directory of Open Access Journals (Sweden)

    Caroline Lustenberger

    Full Text Available EEG sleep spindle activity (SpA during non-rapid eye movement (NREM sleep has been reported to be associated with measures of intelligence and overnight performance improvements. The reticular nucleus of the thalamus is generating sleep spindles in interaction with thalamocortical connections. The same system enables efficient encoding and processing during wakefulness. Thus, we examined if the triangular relationship between SpA, measures of intelligence and declarative learning reflect the efficiency of the thalamocortical system. As expected, SpA was associated with general cognitive ability, e.g. information processing speed. SpA was also associated with learning efficiency, however, not with overnight performance improvement in a declarative memory task. SpA might therefore reflect the efficiency of the thalamocortical network and can be seen as a marker for learning during encoding in wakefulness, i.e. learning efficiency.

  7. Microbial Activity Influences Electrical Conductivity of Biofilm Anode

    Science.gov (United States)

    This study assessed the conductivity of a Geobacter-enriched biofilm anode along with biofilm activity in a microbial electrochemical cell (MxC) equipped with two gold anodes (25 mM acetate medium), as different proton gradients were built throughout the biofilm. There was no pH ...

  8. Influence of osmotic and metal stresses on nitrogenase activity of ...

    African Journals Online (AJOL)

    Samples were collected from paddy fields in Corum-Turk.ye. Nitrogen-free BG-11 medium was used for isolation of nitrogen fixing cyanobacteria. Acetylene reduction technique was used to determine the effects of different chemical agents on the nitrogenase activities of the cyanobacteria, which were identified at the genus ...

  9. Factors influencing beta-amylase activity in sorghum malt

    CSIR Research Space (South Africa)

    Taylor, JRN

    1993-09-01

    Full Text Available isozyme of pI approximately 4.4-4.5, unlike the many isozymes all of higher pI in barley. However, like barley, sorghum beta-amylase was more temperature-labile than its alpha-amylase. Beta-amylase activity in sorghum malt was increased by germination time...

  10. Factors Influencing Physical Activity among Postpartum Iranian Women

    Science.gov (United States)

    Roozbahani, Nasrin; Ghofranipour, Fazlollah; Eftekhar Ardabili, Hassan; Hajizadeh, Ebrahim

    2014-01-01

    Background: Postpartum women are a population at risk for sedentary living. Physical activity (PA) prior to pregnancy may be effective in predicting similar behaviour in the postpartum period. Objective: To test a composite version of the extended transtheoretical model (TTM) by adding "past behaviour" in order to predict PA behaviour…

  11. Influence of surface-imprinted nanoparticles on trypsin activity.

    Science.gov (United States)

    Guerreiro, António; Poma, Alessandro; Karim, Kal; Moczko, Ewa; Takarada, Jessica; de Vargas-Sansalvador, Isabel Perez; Turner, Nicholas; Piletska, Elena; de Magalhães, Cristiana Schmidt; Glazova, Natalia; Serkova, Anastasia; Omelianova, Aleksandra; Piletsky, Sergey

    2014-09-01

    Here, the modulation of enzyme activity is presented by protein-imprinted nanoparticles produced using a solid-phase approach. Using trypsin as target, binding of the nanoparticles to the enzyme results in its inhibition or in stabilization, depending on the orientation of the immobilized enzyme used during imprinting. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Influence of osmotic and metal stresses on nitrogenase activity of ...

    African Journals Online (AJOL)

    SERVER

    2007-08-06

    Aug 6, 2007 ... metal requirements often absent in other bacteria; copper ... Table 1. The effect of salt concentrations on nitrogenase activity in nitrogen-fixing Anabaena, Nostoc and Nodularia spp. ... as a detoxification mechanism. ..... the critical iron toxicity contents of paddy are above 500 .... Isolation of nickel dependent.

  13. Influence of In vitro Digestion on Antioxidative Activity of Coconut ...

    African Journals Online (AJOL)

    Purpose: To investigate the antioxidative stability of coconut meat protein hydrolysates (CMPHs) in the gastrointestinal tract, and evaluate the changes in antioxidant activity, amino acid composition and molecular weight distribution of CMPHs during gastrointestinal (GI )digestion. Methods: A two-stage in vitro digestion ...

  14. Diet Modifies the Neuroimmune System by Influencing Macrophage Activation

    Science.gov (United States)

    Sherry, Christina Lynn

    2009-01-01

    It has long been appreciated that adequate nutrition is required for proper immune function and it is now recognized that dietary components contribute to modulation of immune cells, subsequently impacting the whole body's response during an immune challenge. Macrophage activation plays a critical role in the immune system and directs the…

  15. Influence of highly active antiretroviral therapy (HAART) on the ...

    African Journals Online (AJOL)

    This report is part of the ongoing highly active antiretroviral therapy (HAART) trial, 167 patients were enlisted, but current analysis was restricted to 107 patients that were about a year old on the programme. The baseline weight, CD4+ cell count and serum albumin of 59 males and 48 females age 15-60 years, were ...

  16. Factors influencing activity of triazole fungicides towards Botrytis cinerea.

    NARCIS (Netherlands)

    Stehmann, C.; Waard, de M.A.

    1996-01-01

    The activity of triazole fungicides towards Botrytis cinerea was investigated in vitro (radial growth on fungicide-amended agar) and in vivo (foliar-sprayed tomato plants and dip-treated grapes). In both tests the benzimidazoles, benomyl and thiabendazole, and the dicarboximides, iprodione and

  17. Household factors influencing participation in bird feeding activity

    DEFF Research Database (Denmark)

    Davies, Zoe G.; Fuller, Richard A.; Dallimer, Martin

    2012-01-01

    whether and how the socioeconomic background of a household influences participation in food provision for wild birds, the most popular and widespread form of human-wildlife interaction. A majority of households feed birds (64% across rural and urban areas in England, and 53% within five British study...... cities). House type, household size and the age of the head of the household were all important predictors of bird feeding, whereas gross annual household income, the occupation of the head of the household, and whether the house is owned or rented were not. In both surveys, the prevalence of bird...... a week. The proportion of households regularly feeding birds was positively related to the age of the head of the household, but declined with gross annual income. As concerns grow about the lack of engagement between people and the natural environment, such findings are important if conservation...

  18. PHYSICAL ACTIVITY INFLUENCE ON NUTRITIONAL STATUS OF PRESCHOOL CHILDREN

    Directory of Open Access Journals (Sweden)

    Olivera Radulović

    2010-03-01

    Full Text Available The prevalence of excessive body weight and obesity among children is increasing in many countries, including our country. It is believed that one of the two most important reasons for this increase is insufficient physical activity of children.The aim of this study was to examine the state of the level of nourishment of preschool children in relation to their level of physical activity. The survey was conducted in preschools in Pancevo. The sample consisted of 193 children (88 boys and 105 girls, aged 4 and 5 years. The assessment of the level of nourishment of the children and their parents was done after the standard anthropometric measurements of height, body weight, determining the body mass index and waist circumference and comparing the obtained values with the growth plates given by World Health Organization. Physical activity of the children was evaluated by a questionnaire which parents filled up. Inappropriate level of nourishment had 60 (31.1% children, of which 26 (13.5% with excessive body mass, obese 29 (15.0%, while 5 (2.5% were malnourished. Children are most attracted to sports such as ballet or folk dances, ball games and swimming, but only 22 (15.83% children are members of some sports club. The lack of finances and the lack of sports facilities and terrains are given as reasons by most parents. During the implementation of physical activities, 65.2% of children are never or sometimes exposed to excessive physical effort. The prevalence of insufficient physical activity among preschool children in Pancevo was high, particularly among children with excessive body weight and obese children. Socio-demographic and behavioral factors as well as behavior of parents significantly contributed to physical inactivity.

  19. Influence of vestibular activation on respiration in humans

    Science.gov (United States)

    Monahan, Kevin D.; Sharpe, Melissa K.; Drury, Daniel; Ertl, Andrew C.; Ray, Chester A.

    2002-01-01

    The purpose of this study was to determine the effects of the semicircular canals and otolith organs on respiration in humans. On the basis of animal studies, we hypothesized that vestibular activation would elicit a vestibulorespiratory reflex. To test this hypothesis, respiratory measures, arterial blood pressure, and heart rate were measured during engagement of semicircular canals and/or otolith organs. Dynamic upright pitch and roll (15 cycles/min), which activate the otolith organs and semicircular canals, increased respiratory rate (Delta2 +/- 1 and Delta3 +/- 1 breaths/min, respectively; P < 0.05). Dynamic yaw and lateral pitch (15 cycles/min), which activate the semicircular canals, increased respiration similarly (Delta3 +/- 1 and Delta2 +/- 1, respectively; P < 0.05). Dynamic chair rotation (15 cycles/min), which mimics dynamic yaw but eliminates neck muscle afferent, increased respiration (Delta3 +/- 1; P < 0.05) comparable to dynamic yaw (15 cycles/min). Increases in respiratory rate were graded as greater responses occurred during upright (Delta5 +/- 2 breaths/min) and lateral pitch (Delta4 +/- 1) and roll (Delta5 +/- 1) performed at 30 cycles/min. Increases in breathing frequency resulted in increases in minute ventilation during most interventions. Static head-down rotation, which activates otolith organs, did not alter respiratory rate (Delta1 +/- 1 breaths/min). Collectively, these data indicate that semicircular canals, but not otolith organs or neck muscle afferents, mediate increased ventilation in humans and support the concept that vestibular activation alters respiration in humans.

  20. Neighborhood Influences on Late Life Cognition in the ACTIVE Study

    Directory of Open Access Journals (Sweden)

    Shannon M. Sisco

    2012-01-01

    Full Text Available Low neighborhood-level socioeconomic status has been associated with poorer health, reduced physical activity, increased psychological stress, and less neighborhood-based social support. These outcomes are correlates of late life cognition, but few studies have specifically investigated the neighborhood as a unique source of explanatory variance in cognitive aging. This study supplemented baseline cognitive data from the ACTIVE (Advanced Cognitive Training for Independent and Vital Elderly study with neighborhood-level data to investigate (1 whether neighborhood socioeconomic position (SEP predicts cognitive level, and if so, whether it differentially predicts performance in general and specific domains of cognition and (2 whether neighborhood SEP predicts differences in response to short-term cognitive intervention for memory, reasoning, or processing speed. Neighborhood SEP positively predicted vocabulary, but did not predict other general or specific measures of cognitive level, and did not predict individual differences in response to cognitive intervention.

  1. Influence of Math Club Activities on Primary Students’ Mathematics Achievement

    Directory of Open Access Journals (Sweden)

    Alenka Lipovec

    2014-12-01

    Full Text Available An intervention program called Didactic pentagon is described. Participants are teachers, students, parents, pre-service teachers and teacher educators. The programme is shaped as a math club activity. Empirical results focus on comparing mathematics achievements of students included in the programme and mathematically promising students taking part in TIMSS 2003. Experimental group has surpassed control group in overall results. Statistically significant differences in favour of experimental group can be found at intermediate international benchmark of mathematics achievements and at problem solving cognitive domain. The results can be assigned to pentagon activities guided by pre-service teachers. Cooperation between university and schools has evidently overcome the lack of pre-service teachers’ experience and helped in raising mathematical knowledge of school youth.

  2. Influence of thorax irradiation on lactic dehydrogenase isoenzyme activity

    International Nuclear Information System (INIS)

    Valle, C.; Munnich, A.; Pasquier, C.

    The right hemi-thorax of rats was irradiated with 1200 and 3000 rads ( 60 Co) and blood samples were taken sequentially. The five lactic dehydrogenase (LDH) isoenzymes which have proved to be useful as biochemical indicators of acute pulmonary injury in other experimental animals (dogs), were assayed, after irradiation, as a function of time and as a functon of dose. There was no significant change in LDH isoenzyme activities after lung irradiation in rats [fr

  3. Influence of the day care, home and neighbourhood environment on young children's physical activity and health

    DEFF Research Database (Denmark)

    Christian, Hayley; Maitland, Clover; Enkel, Stephanie

    2016-01-01

    to determine outdoor location of physical activity around the home and neighbourhood for a subsample (n=310). The day care environment will be objectively measured using a validated audit tool. Other potential individual, social and physical environmental influences on preschoolers' physical activity...... such as long day care. Research is required to determine how the design of day care outdoor (and indoor) spaces provides opportunities or constraints for physical activity. A significant evidence gap surrounds what objectively measured attributes of the home and neighbourhood environment influence preschoolers......' physical activity. The PLAY Spaces & Environments for Children's Physical Activity (PLAYCE) study will empirically investigate the relative and cumulative influence of the day care, home and neighbourhood environment on preschoolers' physical activity. METHODS AND ANALYSIS: The PLAYCE study is a cross...

  4. Influence of Friends on Children’s Physical Activity: A Review

    OpenAIRE

    Maturo, Claire C.; Cunningham, Solveig A.

    2013-01-01

    We examined evidence for friendship influences on children’s physical activity (PA) through systematic searches of online databases in May 2012. We identified 106 studies (25 qualitative) published in English since 2000 that analyzed indicators of friendship influences (e.g., communication about PA, friends’ PA, and PA with friends) among persons younger than 19 years.

  5. The influence of business strategy on new product activity: the role of market orientation

    NARCIS (Netherlands)

    Frambach, R.T.; Prabhu, Jaideep; Verhallen, T.M.M.

    2003-01-01

    In this paper, we propose that business strategy influences new product activity both directly and indirectly via its influence on market orientation. Accordingly, we develop a framework linking firms' relative emphasis on cost leadership, product differentiation and focus strategies to firms'

  6. Effects of age and spa treatment on match running performance over two consecutive games in highly trained young soccer players.

    Science.gov (United States)

    Buchheit, Martin; Horobeanu, Cosmin; Mendez-Villanueva, Alberto; Simpson, Ben M; Bourdon, Pitre C

    2011-03-01

    The aim of this study was to examine the effect of age and spa treatment (i.e. combined sauna, cold water immersion, and jacuzzi) on match running performance over two consecutive matches in highly trained young soccer players. Fifteen pre- (age 12.8 ± 0.6 years) and 13 post- (15.9 ± 1 y) peak height velocity (PHV) players played two matches (Matches 1 and 2) within 48 h against the same opposition, with no specific between-match recovery intervention (control). Five post-PHV players also completed another set of two consecutive matches, with spa treatment implemented after the first match. Match running performance was assessed using a global positioning system with very-high-intensity running (> 16.1-19.0 km · h(-1)), sprinting distance (>19 km · h(-1)), and peak match speed determined. Match 2 very-high-intensity running was "possibly" impaired in post-PHV players (-9 ± 33%; ± 90% confidence limits), whereas it was "very likely" improved for the pre-PHV players (+27 ± 22%). The spa treatment had a beneficial impact on Match 2 running performance, with a "likely" rating for sprinting distance (+30 ± 67%) and "almost certain" for peak match speed (+6.4 ± 3%). The results suggest that spa treatment is an effective recovery intervention for post-PHV players, while its value in pre-PHV players is questionable.

  7. 75 FR 65263 - Virginia Graeme Baker Pool and Spa Safety Act; Public Accommodation; Withdrawal of Proposed Rule

    Science.gov (United States)

    2010-10-22

    ...'' or ``Act'') as ``an inn, hotel, motel, or other place of lodging, except for an establishment located... interpretive rule to interpret ``public accommodations facility'' in the VGB Act as ``an inn, hotel, motel, or... CONSUMER PRODUCT SAFETY COMMISSION 16 CFR Part 1450 Virginia Graeme Baker Pool and Spa Safety Act...

  8. LHC suppliers win Golden Hadron awards : Gianfranco Malvestiti and Ernesto Malvestiti de Ernesto Malvestiti SpA (Italie)

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    Ernesto Malvestiti SpA (Italy) is the main manufacturer of the metal collars needed to ensure the rigidity of the superconducting dipoles. The firm was awarded its prize in recognition of the central role it played during the transition from aluminium to stainless-steel collars.

  9. 75 FR 22512 - Airworthiness Directives; Piaggio Aero Industries S.p.A. Model PIAGGIO P-180 Airplanes

    Science.gov (United States)

    2010-04-29

    ... Airworthiness Directives; Piaggio Aero Industries S.p.A. Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation... presence of potential ignition sources such as electrical equipment and connectors. As a consequence, this..., agree with their substance. But we might have found it necessary to use different words from those in...

  10. 75 FR 67639 - Airworthiness Directives; Piaggio Aero Industries S.p.A Model PIAGGIO P-180 Airplanes

    Science.gov (United States)

    2010-11-03

    ... Friday, except Federal holidays. For service information identified in this proposed AD, contact Piaggio... Piaggio Aero Industries have issued service information (referred to after this as ``the MCAI''), to... Information Piaggio Aero Industries S.p.A. has issued Service Bulletin (Mandatory) N.: SB 80-0275, Rev. N. 0...

  11. 76 FR 7694 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Science.gov (United States)

    2011-02-11

    ... Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes AGENCY: Federal Aviation... Piaggio service bulletin number specified in the Alternative Methods of Compliance (AMOCs) section is..., except Federal holidays. The AD docket contains this AD, the regulatory evaluation, any comments received...

  12. 76 FR 4056 - Airworthiness Directives; PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P-180 Airplanes

    Science.gov (United States)

    2011-01-24

    ..., is considered the State of Design for PIAGGIO AERO INDUSTRIES S.p.A Model PIAGGIO P- 180 airplanes. A... ensuring that the drain lines of the environmental unit condenser are not clogged. Since AD 2007-24-15... condition described previously is likely to exist or develop in other products of the same type design. AD...

  13. SP-A-enriched surfactant for treatment of rat lung transplants with SP-A deficiency after storage and reperfusion

    NARCIS (Netherlands)

    Erasmus, ME; Hofstede, GJH; Petersen, AH; Batenburg, JJ; Haagsman, HP; Oetomo, SB; Prop, J

    2002-01-01

    Background. The function of pulmonary surfactant is affected by lung transplantation, contributing to impaired lung transplant function. A decreased amount of surfactant protein-A (SP-A) after reperfusion is believed to contribute to the impaired surfactant function. Surfactant treatment has been

  14. The Interplay of Networking Activities and Internal Knowledge Actions for Subsidiary Influence within MNCs

    DEFF Research Database (Denmark)

    Tavani, Zhaleh Najafi; Giroud, Axèle; Andersson, Ulf

    2012-01-01

    Building on resource dependency theory; this research investigates the joint impacts of subsidiary knowledge based actions (Reverse Knowledge Transfer (RKT) and knowledge development) and networking activities (internal and external embeddedness) on its strategic influence in the multinational co...

  15. Physical activity in adolescents: analysis of social influence of parents and friends

    Directory of Open Access Journals (Sweden)

    Luanna Alexandra Cheng

    2014-01-01

    Conclusions: Parents and friends have a social influence on adolescents’ level of physical activity through the mechanism of behavior modeling or through social support, mediated by self‐efficacy.

  16. Influence of geomagnetic activity and atmospheric pressure in hypertensive adults.

    Science.gov (United States)

    Azcárate, T; Mendoza, B

    2017-09-01

    We performed a study of the systolic and diastolic arterial blood pressure behavior under natural variables such as the atmospheric pressure and the horizontal geomagnetic field component. We worked with a group of eight adult hypertensive volunteers, four men and four women, with ages between 18 and 27 years in Mexico City during a geomagnetic storm in 2014. The data was divided by gender, age, and day/night cycle. We studied the time series using three methods: correlations, bivariate analysis, and superposed epoch (within a window of 2 days around the day of occurrence of a geomagnetic storm) analysis, between the systolic and diastolic blood pressure and the natural variables. The correlation analysis indicated a correlation between the systolic and diastolic blood pressure and the atmospheric pressure and the horizontal geomagnetic field component, being the largest during the night. Furthermore, the correlation and bivariate analyses showed that the largest correlations are between the systolic and diastolic blood pressure and the horizontal geomagnetic field component. Finally, the superposed epoch analysis showed that the largest number of significant changes in the blood pressure under the influence of geomagnetic field occurred in the systolic blood pressure for men.

  17. The Influence of nonuniform activity distribution on cellular dosimetry

    International Nuclear Information System (INIS)

    Naling, Song; Yuan, Tian; Liangan, Zhang; Guangfu, Dai

    2008-01-01

    S value is an important parameter in determination of absorbed dose in nuclear medicine and radiobiology. The distribution of radioactivity shows significant influence on the S value especially in microdosimetry. In present work, a semi Monte Carlo Model is developed to calculate the microdosimetric cellular S value for different micro-distributions of radioactivity, i.e. uniform, linear increase, linear decrease, exponential increase, exponential decrease and centroid distribution. Emission of alpha particles is simulated by Monte Carlo model and the energy imparted to the target volume is calculated by the analytical Continuous Slowing Down Approximation (CSDA) model and the spline interpolation of range-energy relationship. We calculate tables of S values for 213 Po and 210 Po with various dimensions and most important with various possible micro-distributions of radioactivity, such as linear increase, linear decrease, exponential increase and exponential decrease. Then we compare the S values from cell to cell of uniform distribution with the Hamacher's results to test the feasibility of our model. S values of some nonuniform micro-distributions are compared to the corresponding data of the uniform distribution. The possible sources of these differences are theoretical analyzed. (author)

  18. Influence of geomagnetic activity and atmospheric pressure in hypertensive adults

    Science.gov (United States)

    Azcárate, T.; Mendoza, B.

    2017-09-01

    We performed a study of the systolic and diastolic arterial blood pressure behavior under natural variables such as the atmospheric pressure and the horizontal geomagnetic field component. We worked with a group of eight adult hypertensive volunteers, four men and four women, with ages between 18 and 27 years in Mexico City during a geomagnetic storm in 2014. The data was divided by gender, age, and day/night cycle. We studied the time series using three methods: correlations, bivariate analysis, and superposed epoch (within a window of 2 days around the day of occurrence of a geomagnetic storm) analysis, between the systolic and diastolic blood pressure and the natural variables. The correlation analysis indicated a correlation between the systolic and diastolic blood pressure and the atmospheric pressure and the horizontal geomagnetic field component, being the largest during the night. Furthermore, the correlation and bivariate analyses showed that the largest correlations are between the systolic and diastolic blood pressure and the horizontal geomagnetic field component. Finally, the superposed epoch analysis showed that the largest number of significant changes in the blood pressure under the influence of geomagnetic field occurred in the systolic blood pressure for men.

  19. Influence of physical activity on psychosomatic health in obese women.

    Science.gov (United States)

    Menzyk, K; Cajdler, A; Pokorski, M

    2008-12-01

    It is unclear to what extent the known psychosomatic benefits of exercise hold true for the obese. In the present study, we investigated the hypothesis that the psychosomatic health and components of general intelligence, such as the capacity for logical-deductive tasks, would be better in regularly exercising than non-exercising obese women. We addressed the issue in a self-reported survey study, comprising two groups of middle-aged obese women (age 30-50 years, BMI >30 kg/m(2)) of 25 persons each. The criterion for the group division was regular exercise, minimum twice a week, for at least 2 months. The following psychometric tools were used: Physical Fitness and Exercise Scale, Patient Health Questionnaire-9 for depression, Life Satisfaction Scale, General Health Inventory-28, Raven's Matrices Test for intelligence, and a test for selfcontentment with one's body figure shape. The exercising obese women scored significantly better in Life Satisfaction Scale (17.1 +/- 1.2 vs.12.0 +/- 0.9), had a lower level of depression (8.1 +/- 0.6 vs. 13.4 +/- 0.7), and a better assessment of the health status (24.6 +/- 1.6 vs. 36.4 +/- 2.2) (reversed score) compared with non-exercising ones (Pexercising obese women also appreciably better assessed their bodily looks. Interestingly, if depression was present in exercising women, it had more detrimental health effects than in physically inactive ones. The study failed to substantiate appreciable changes in general intelligence between active and non-active obese women. In conclusion, physical activity is of benefit for the psychosomatic health in obese women, which should be considered in behavioral counseling.

  20. Influence of phasic and tonic dopamine release on receptor activation

    DEFF Research Database (Denmark)

    Dreyer, Jakob Kristoffer Kisbye; Herrik, Kjartan F; Berg, Rune W

    2010-01-01

    Tonic and phasic dopamine release is implicated in learning, motivation, and motor functions. However, the relationship between spike patterns in dopaminergic neurons, the extracellular concentration of dopamine, and activation of dopamine receptors remains unresolved. In the present study, we...... develop a computational model of dopamine signaling that give insight into the relationship between the dynamics of release and occupancy of D(1) and D(2) receptors. The model is derived from first principles using experimental data. It has no free parameters and offers unbiased estimation...

  1. Influence of fillers on the alkali activated chamotte

    Science.gov (United States)

    Dembovska, L.; Bumanis, G.; Vitola, L.; Bajare, D.

    2017-10-01

    Alkali-activated materials (AAM) exhibit remarkable high-temperature resistance which makes them perspective materials for high-temperature applications, for instance as fire protecting and insulating materials in industrial furnaces. Series of experiments were carried out to develop optimum mix proportions of AAM based on chamotte with quartz sand (Q), olivine sand (OL) and firebrick sawing residues (K26) as fillers. Aluminium scrap recycling waste was considered as a pore forming agent and 6M NaOH alkali activation solution has been used. Lightweight porous AAM have been obtained with density in range from 600 to 880 kg/m3 and compressive strength from 0.8 to 2.7 MPa. The XRD and high temperature optical microscopy was used to characterize the performance of AAM. The mechanical, physical and structural properties of the AAM were determined after the exposure to elevated temperatures at 800 and 1000°C. The results indicate that most promising results for AAM were with K26 filler where strength increase was observed while Q and OL filler reduced mechanical properties due to structure deterioration caused by expansive nature of selected filler.

  2. Effects of voluntary exercise on spontaneous physical activity and food consumption in mice: Results from an artificial selection experiment.

    Science.gov (United States)

    Copes, Lynn E; Schutz, Heidi; Dlugosz, Elizabeth M; Acosta, Wendy; Chappell, Mark A; Garland, Theodore

    2015-10-01

    We evaluated the effect of voluntary exercise on spontaneous physical activity (SPA) and food consumption in mice from 4 replicate lines bred for 57 generations for high voluntary wheel running (HR) and from 4 non-selected control (C) lines. Beginning at ~24 days of age, mice were housed in standard cages or in cages with attached wheels. Wheel activity and SPA were monitored in 1-min intervals. Data from the 8th week of the experiment were analyzed because mice were sexually mature and had plateaued in body mass, weekly wheel running distance, SPA, and food consumption. Body mass, length, and masses of the retroperitoneal fat pad, liver, and heart were recorded after the 13th week. SPA of both HR and C mice decreased with wheel access, due to reductions in both duration and average intensity of SPA. However, total activity duration (SPA+wheel running; min/day) was ~1/3 greater when mice were housed with wheels, and food consumption was significantly increased. Overall, food consumption in both HR and C mice was more strongly affected by wheel running than by SPA. Duration of wheel running had a stronger effect than average speed, but the opposite was true for SPA. With body mass as a covariate, chronic wheel access significantly reduced fat pad mass and increased heart mass in both HR and C mice. Given that both HR and C mice housed with wheels had increased food consumption, the energetic cost of wheel running was not fully compensated by concomitant reductions in SPA. The experiment demonstrates that both duration and intensity of both wheel running and SPA were significant predictors of food consumption. This sort of detailed analysis of the effects of different aspects of physical activity on food consumption has not previously been reported for a non-human animal, and it sets the stage for longitudinal examination of energy balance and its components in rodent models. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Factors influencing quality of life in patients with active tuberculosis.

    Science.gov (United States)

    Marra, Carlo A; Marra, Fawziah; Cox, Victoria C; Palepu, Anita; Fitzgerald, J Mark

    2004-10-20

    With effective treatment strategies, the focus of tuberculosis (TB) management has shifted from the prevention of mortality to the avoidance of morbidity. As such, there should be an increased focus on quality of life (QoL) experienced by individuals being treated for TB. The objective of our study was to identify areas of QoL that are affected by active TB using focus groups and individual interviews. English, Cantonese, and Punjabi-speaking subjects with active TB who were receiving treatment were eligible for recruitment into the study. Gender-based focus group sessions were conducted for the inner city participants but individual interviews were conducted for those who came to the main TB clinic or were hospitalized. Facilitators used open-ended questions and participants were asked to discuss their experiences of being diagnosed with tuberculosis, what impact it had on their lives, issues around adherence to anti-TB medications and information pertaining to their experience with side effects to these medications. All data were audio-recorded, transcribed verbatim, and analyzed using constant comparative analysis. 39 patients with active TB participated. The mean age was 46.2 years (SD 18.4) and 62% were male. Most were Canadian-born being either Caucasian or Aboriginal. Four themes emerged from the focus groups and interviews. The first describes issues related to the diagnosis of tuberculosis and sub-themes were identified as 'symptoms', 'health care provision', and 'emotional impact'. The second theme discusses TB medication factors and the sub-themes identified were 'adverse effects', 'ease of administration', and 'adherence'. The third theme describes social support and functioning issues for the individuals with TB. The fourth theme describes health behavior issues for the individuals with TB and the identified sub-themes were "behavior modification" and "TB knowledge." Despite the ability to cure TB, there remains a significant impact on QOL. Since much

  4. Factors influencing quality of life in patients with active tuberculosis

    Directory of Open Access Journals (Sweden)

    Cox Victoria C

    2004-10-01

    Full Text Available Abstract Background With effective treatment strategies, the focus of tuberculosis (TB management has shifted from the prevention of mortality to the avoidance of morbidity. As such, there should be an increased focus on quality of life (QoL experienced by individuals being treated for TB. The objective of our study was to identify areas of QoL that are affected by active TB using focus groups and individual interviews. Methods English, Cantonese, and Punjabi-speaking subjects with active TB who were receiving treatment were eligible for recruitment into the study. Gender-based focus group sessions were conducted for the inner city participants but individual interviews were conducted for those who came to the main TB clinic or were hospitalized. Facilitators used open-ended questions and participants were asked to discuss their experiences of being diagnosed with tuberculosis, what impact it had on their lives, issues around adherence to anti-TB medications and information pertaining to their experience with side effects to these medications. All data were audio-recorded, transcribed verbatim, and analyzed using constant comparative analysis. Results 39 patients with active TB participated. The mean age was 46.2 years (SD 18.4 and 62% were male. Most were Canadian-born being either Caucasian or Aboriginal. Four themes emerged from the focus groups and interviews. The first describes issues related to the diagnosis of tuberculosis and sub-themes were identified as 'symptoms', 'health care provision', and 'emotional impact'. The second theme discusses TB medication factors and the sub-themes identified were 'adverse effects', 'ease of administration', and 'adherence'. The third theme describes social support and functioning issues for the individuals with TB. The fourth theme describes health behavior issues for the individuals with TB and the identified sub-themes were "behavior modification" and "TB knowledge." Conclusion Despite the ability to

  5. Hyperspectral Imaging and SPA-LDA Quantitative Analysis for Detection of Colon Cancer Tissue

    Science.gov (United States)

    Yuan, X.; Zhang, D.; Wang, Ch.; Dai, B.; Zhao, M.; Li, B.

    2018-05-01

    Hyperspectral imaging (HSI) has been demonstrated to provide a rapid, precise, and noninvasive method for cancer detection. However, because HSI contains many data, quantitative analysis is often necessary to distill information useful for distinguishing cancerous from normal tissue. To demonstrate that HSI with our proposed algorithm can make this distinction, we built a Vis-NIR HSI setup and made many spectral images of colon tissues, and then used a successive projection algorithm (SPA) to analyze the hyperspectral image data of the tissues. This was used to build an identification model based on linear discrimination analysis (LDA) using the relative reflectance values of the effective wavelengths. Other tissues were used as a prediction set to verify the reliability of the identification model. The results suggest that Vis-NIR hyperspectral images, together with the spectroscopic classification method, provide a new approach for reliable and safe diagnosis of colon cancer and could lead to advances in cancer diagnosis generally.

  6. Single Piezo-Actuator Rotary-Hammering (SPaRH) Drill

    Science.gov (United States)

    Sherrit, Stewart (Inventor); Bao, Xiaoqi (Inventor); Badescu, Mircea (Inventor); Bar-Cohen, Yoseph (Inventor)

    2014-01-01

    A Single Piezo-Actuator Rotary-Hammering (SPaRH) Drill includes a horn actuator having high power piezoelectric materials and a flexure pre-stress to increase the actuators effectiveness. The drill is a low mass, low power, compact coring drill measuring 20-cm high by 7-cm diameter and having a total weight of 2 kg including drive electronics. Using an average power of 50-Watts, the drill basalt is expected to cut basalt at a rate of 0.2 cm/min down to depth of 10-cm and create cuttings and an intact core. The drill is expected to operate under different environments including Martian ambient (6 Torr and down to -50 degree C), and liquid nitrogen temperatures (77 K) and low pressure (<<1 Torr) to simulate lunar polar and Europa conditions. Materials expected to be sampled include Kaolinite, Saddleback Basalt, Limestone, Volcanic Breccia, Siltstone, ice, permafrost and layered rocks with different hardness.

  7. Tourist phenomenon in Geoagiu Spa region within the Central Metaliferi Mountains

    Directory of Open Access Journals (Sweden)

    Dombay Ştefan

    2010-01-01

    Full Text Available The Central Metaliferi Mountains, situated in south-central side of the Apuseni Mountains, have a variety of natural and anthropic touristic potential, but, unfortunately, less known and not enough exploited. After conducting a survey in Geoagiu Spa we specifically recommend the following: increased number of one day tours, which are the main tourist destination in the region, many tours for visiting the major centers of cultural - historical monuments related to our past history, granting economic incentives for organizer of youth groups to attract the youth, diversification of tourist routes with thematic actions: curiosities of nature, environment, organizing sports events with different timetable covering all seasons and all series, attracting local and foreign investors by providing tax incentives and financial programs introducing touristic resort in the international circuit. .

  8. Perceptions of Physical Activity and Influences of Participation in Young African-American Adolescent Girls.

    Science.gov (United States)

    Morrison, Shannon; Knight, Candace; Crew-Gooden, Annette

    2015-12-01

    The purpose of this study was to explore African-American adolescent girls' perceptions of physical activity participation, examine how physical activity is defined and identify the most preferred forms of physical activity. Qualitative focus group interviews of a convenience sample (N = 30; Mean age = 14.3 years) were used to identifyfactors that influence African-American girls' physical activity participation as well as to explore how physical activity is defined within this population. Four themes emerged: (a) benefits and motivation to engage in physical activity, (b) behaviors consistent with perceived physical activity, (c) most enjoyable physical activity/activities, and (d) barriers to physical activity. Physical activities that promoted normative adolescent development (i.e., autonomy) were perceived as most beneficial, desirable, and most likely to be sustained. Implications of these findings highlight the importance of the incorporation of socialization and peer engagement in physical activity programs designed for African-American adolescent girls.

  9. Periodic sediment shift in migrating ripples influences benthic microbial activity

    Science.gov (United States)

    Zlatanović, Sanja; Fabian, Jenny; Mendoza-Lera, Clara; Woodward, K. Benjamin; Premke, Katrin; Mutz, Michael

    2017-06-01

    Migrating bedforms have high levels of particulate organic matter and high rates of pore water exchange, causing them to be proposed as hot spots of carbon turnover in rivers. Yet, the shifting of sediments and associated mechanical disturbance within migrating bedforms, such as ripples, may stress and abrade microbial communities, reducing their activity. In a microcosm experiment, we replicated the mechanical disturbances caused by the periodic sediment shift within ripples under oligotrophic conditions. We assessed the effects on fungal and bacterial biomass ratio (F:B), microbial community respiration (CR), and bacterial production (BCP) and compared with stable undisturbed sediments. Interactions between periodic mechanical disturbance and sediment-associated particulate organic matter (POM) were tested by enriching sediments collected from migrating ripples with different qualities of POM (fish feces, leaf litter fragments and no addition treatments). F:B and BCP were affected by an interaction between mechanical disturbance and POM quality. Fish feces enriched sediments showed increased F:B and BCP compared to sediments with lower POM quality and responded with a decrease of F:B and BCP to sediment disturbance. In the other POM treatments F:B and BCP were not affected by disturbance. Microbial respiration was however reduced by mechanical disturbance to similar low activity levels regardless of POM qualities added, whereas fish feces enriched sediment showed short temporary boost of CR. With the worldwide proliferation of migrating sand ripples due to massive catchment erosion, suppressed mineralization of POM will increasingly affect stream metabolism, downstream transport of POM and carbon cycling from reach to catchment scale.

  10. INFLUENCE OF BIOLOGICALLY ACTIVE SUBSTANCES ON TOMATO YIELD AND QUALITY

    Directory of Open Access Journals (Sweden)

    G. I. Yarovoy

    2017-01-01

    Full Text Available The study of influence of growth regulators and biopreparations affecting on decrease of disease development, increase of yield capacity and final product quality was carried out in tomato. It was shown that all preparations were effective in decreasing the process of diseases development and increasing the yield capacity and product quality. The studies were carried out in the experimental fields at the Institute of Vegetables and Melons NAAS, in Ukraine in 2011-2012. The field studies were performed according to ‘Methodology of Experimental Work in Vegetable and Melon Growing’ on area sown with cultivars ‘Karas’ and ‘Kremenchugskiy’. The fungicides ‘Mars U 77%’, ‘Vimpel with Fitotsid’, ‘Vermistim’ wth ‘Azotofit’ and ‘Bioglobin’ with ‘Azotofit’ were used on cultivars of tomato, as control were the plants without treatment. It was determined that all preparations decreased the development of diseases. On average, the development of early dry spot had decreased by 12.2–16.1% and anthracnose by 10.0–12.6% in the cultivars ‘Kremenchugskiy’ and ‘Karas’. Thus, biopreparations used on the varieties ‘Kremenchugskiy’ and ‘Karas’ were effective in decrease of disease development, such as early dry spot, anthracnose, in a range of 39.1–52.7 %. Generally, during observation period the efficacy index of the preparations ‘Vermistim’ with ‘Azotofit’, ‘Bioglobin’ with ‘Azotofit’ was higher than others preparations on the varieties ‘Kremenchug and ‘Karas’ against early dry spot (48.3–50.9%, 50.3–52.7% and anthracnose (46.1–47.0%, 47.6–48.5%. The results showed that the vast majority of biological preparations, phytohormones used against diseases in tomato crops of varieties ‘Kremenchugskiy’ and ‘Karas’, were effective in a range of 39.1-52.7% and also maintained the tomato yield within 2.8-5.1 t/ha or 8.1- 13.9%. The biological preparations, phytohormones improved

  11. A spindle pole antigen gene MoSPA2 is important for polar cell growth of vegetative hyphae and conidia, but is dispensable for pathogenicity in Magnaporthe oryzae.

    Science.gov (United States)

    Li, Chao; Yang, Jun; Zhou, Wei; Chen, Xiao-Lin; Huang, Jin-Guang; Cheng, Zhi-Hua; Zhao, Wen-Sheng; Zhang, Yan; Peng, You-Liang

    2014-11-01

    Spa2 is an important component of the multiprotein complex polarisome, which is involved in the establishment, maintenance, termination of polarized cell growth and is important for defining tip growth of filamentous fungi. In this study, we isolated an insertional mutant of the rice blast fungus Magnaporthe oryzae that formed smaller colony and conidia compared with the wild type. In the mutant, a spindle pole antigen gene MoSPA2 was disrupted by the integration of an exogenous plasmid. Targeted gene deletion and complementation assays demonstrated the gene disruption was responsible for the defects of the insertional mutant. Interestingly, the MoSpa2-GFP fusion protein was found to accumulate as a spot at hyphal tips, septa of hyphae and conidial tip cells where germ tubes are usually produced, but not in appressoria, infection hyphae or at the septa of conidia. Furthermore, the deletion mutants of MoSPA2 exhibited slower hyphal tip growth, more hyphal branches, and smaller size of conidial tip cells. However, MoSPA2 is not required for plant infection. These results indicate that MoSPA2 is required for vegetative hyphal growth and maintaining conidium morphology and that spotted accumulation of MoSpa2 is important for its functions during cell polar growth.

  12. Vasoactive intestinal peptide and electrical activity influence neuronal survival

    International Nuclear Information System (INIS)

    Brenneman, D.E.; Eiden, L.E.

    1986-01-01

    Blockage of electrical activity in dissociated spinal cord cultures results in a significant loss of neurons during a critical period in development. Decreases in neuronal cell numbers and 125 I-labeled tetanus toxin fixation produced by electrical blockage with tetrodotoxin (TTX) were prevented by addition of vasoactive intestinal peptide (VIP) to the nutrient medium. The most effective concentration of VIP was 0.1 nM. At higher concentrations, the survival-enhancing effect of VIP on TTX-treated cultures was attenuated. Addition of the peptide alone had no significant effect on neuronal cell counts or tetanus toxin fixation. With the same experimental conditions, two closely related peptides, PHI-27 (peptide, histidyl-isoleucine amide) and secretin, were found not to increase the number of neurons in TTX-treated cultures. Interference with VIP action by VIP antiserum resulted in neuronal losses that were not significantly different from those observed after TTX treatment. These data indicate that under conditions of electrical blockade a neurotrophic action of VIP on neuronal survival can be demonstrated

  13. Influence of montmorillonite on antimicrobial activity of tetracycline and ciprofloxacin

    Science.gov (United States)

    Lv, Guocheng; Pearce, Cody W.; Gleason, Andrea; Liao, Libing; MacWilliams, Maria P.; Li, Zhaohui

    2013-11-01

    Antibiotics are used not only to fight infections and inhibit bacterial growth, but also as growth promotants in farm livestock. Farm runoff and other farm-linked waste have led to increased antibiotic levels present in the environment, the impact of which is not completely understood. Soil, more specifically clays, that the antibiotic contacts may alter its effectiveness against bacteria. In this study a swelling clay mineral montmorillonite was preloaded with antibiotics tetracycline and ciprofloxacin at varying concentrations and bioassays were conducted to examine whether the antibiotics still inhibited bacterial growth in the presence of montmorillonite. Escherichia coli was incubated with montmorillonite or antibiotic-adsorbed montmorillonite, and then the number of viable bacteria per mL was determined. The antimicrobial activity of tetracycline was affected in the presence of montmorillonite, as the growth of non-resistant bacteria was still found even when extremely high TC doses were used. Conversely, in the presence of montmorillonite, ciprofloxacin did inhibit E. coli bacterial growth at high concentrations. These results suggest that the effectiveness of antimicrobial agents in clayey soils depends on the amount of antibiotic substance present, and on the interactions between the antibiotic and the clays in the soil, as well.

  14. How an active-learning class influences physics self-efficacy in pre-service teachers

    Science.gov (United States)

    Gaffney, Jon D. H.; Housley Gaffney, Amy L.; Usher, Ellen L.; Mamaril, Natasha A.

    2013-01-01

    Education majors in an inquiry-based physics content course were asked to reflect on the ways the course affected their self-efficacy for completing physics tasks, such as creating a circuit. Responses were coded according to the contributor of the influence and whether that influence was positive or negative. The group learning structure, hands-on activities in the class, and the constructed repertoire of science knowledge, processes, and activities, were all reported to be positive influences on self-efficacy, whereas the influence of the instructor was mixed. Overall, students' responses indicated both a desire for more guidance and lecture and an appreciation for their ability to construct their own understanding through the class activities.

  15. Contextual factors influencing leisure physical activity of urbanized indigenous adolescents.

    Science.gov (United States)

    Lo, Feng-En; Tsai, Feng-Chou; Lee, Ming-Been; Tsai, Liang-Ting; Lyu, Shu-Yu; Yang, Chih-Chien

    2015-11-01

    Indigenous populations suffer from disparities in socioeconomic resources and health status. One approach to addressing these disparities is by targeting modifiable risk factors such as leisure physical activity (LPA). This study investigated and compared factors related to LPA among urbanized indigenous and nonindigenous adolescent students. This cross-sectional survey comprised fifth to ninth grade indigenous and nonindigenous students (n = 733). The nonindigenous students were matched with indigenous students on sex and academic achievement and used as a reference group. Data were collected through telephone interviews using structured questionnaires. Major items included: demographic characteristics; average time spent watching television per bout; participation in LPA; and stress and depression experiences. With the exception of the duration of television watching per bout, Chi-square and independent t tests demonstrated that there were no significant differences between indigenous and nonindigenous adolescents in the selected LPA-related factors. Multiple logistic regression analysis including terms investigating interaction between ethnicity and the contextual factors included in this study indicated that the following factors were correlated with LPA participation: age [odds ratio (OR) = 0.82, 95% confidence interval (CI) = 0.71-0.94], male sex (OR = 1.77, 95%CI = 1.19-2.61), total hours spent watching television in the past 2 weeks (OR = 0.79, 95%CI = 0.63-0.99), life satisfaction (OR = 2.25, 95%CI = 1.04-4.90), and exercise enjoyment (OR = 3.40, 95%CI = 1.71-6.74). However, neither indigenous status (OR = 1.03, 95%CI = 0.19-5.79) nor any of the interaction terms reached the significant level. No significant ethnic differences were found in LPA participation. LPA was significantly correlated with age, male sex, total time spent watching television, life satisfaction, and enjoyment of exercise. Copyright © 2014. Published by Elsevier B.V.

  16. Enhanced discrimination of highly clonal ST22-methicillin-resistant Staphylococcus aureus IV isolates achieved by combining spa, dru, and pulsed-field gel electrophoresis typing data.

    LENUS (Irish Health Repository)

    Shore, Anna C

    2010-05-01

    ST22-methicillin-resistant Staphylococcus aureus type IV (ST22-MRSA-IV) is endemic in Irish hospitals and is designated antibiogram-resistogram type-pulsed-field group (AR-PFG) 06-01. Isolates of this highly clonal strain exhibit limited numbers of pulsed-field gel electrophoresis (PFGE) patterns and spa types. This study investigated whether combining PFGE and spa typing with DNA sequencing of the staphylococcal cassette chromosome mec element (SCCmec)-associated direct repeat unit (dru typing) would improve isolate discrimination. A total of 173 MRSA isolates recovered in one Irish hospital during periods in 2007 and 2008 were investigated using antibiogram-resistogram (AR), PFGE, spa, dru, and SCCmec typing. Isolates representative of each of the 17 pulsed-field group 01 (PFG-01) spa types identified underwent multilocus sequence typing, and all isolates were ST22. Ninety-seven percent of isolates (168 of 173) exhibited AR-PFG 06-01 or closely related AR patterns, and 163 of these isolates harbored SCCmec type IVh. The combination of PFGE, spa, and dru typing methods significantly improved discrimination of the 168 PFG-01 isolates, yielding 65 type combinations with a Simpson\\'s index of diversity (SID) of 96.53, compared to (i) pairwise combinations of spa and dru typing, spa and PFGE typing, and dru and PFGE typing, which yielded 37, 44, and 43 type combinations with SIDs of 90.84, 91.00, and 93.57, respectively, or (ii) individual spa, dru, and PFGE typing methods, which yielded 17, 17, and 21 types with SIDs of 66.9, 77.83, and 81.34, respectively. Analysis of epidemiological information for a subset of PFG-01 isolates validated the relationships inferred using combined PFGE, spa, and dru typing data. This approach significantly enhances discrimination of ST22-MRSA-IV isolates and could be applied to epidemiological investigations of other highly clonal MRSA strains.

  17. Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy.

    Science.gov (United States)

    Baeten, Dominique; Kruithof, Elli; De Rycke, Leen; Boots, Anemieke M; Mielants, Herman; Veys, Eric M; De Keyser, Filip

    2005-01-01

    Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis, the present study analyzed whether histopathological features of synovium reflect specific phenotypes and/or global disease activity in SpA. Synovial biopsies obtained from 99 SpA and 86 RA patients with active knee synovitis were analyzed for 15 histological and immunohistochemical markers. Correlations with swollen joint count, serum C-reactive protein concentrations, and erythrocyte sedimentation rate were analyzed using classical and multiparameter statistics. SpA synovitis was characterized by higher vascularity and infiltration with CD163+ macrophages and polymorphonuclear leukocytes (PMNs) and by lower values for lining-layer hyperplasia, lymphoid aggregates, CD1a+ cells, intracellular citrullinated proteins, and MHC-HC gp39 complexes than RA synovitis. Unsupervised clustering of the SpA samples based on synovial features identified two separate clusters that both contained different SpA subtypes but were significantly differentiated by concentration of C-reactive protein and erythrocyte sedimentation rate. Global disease activity in SpA correlated significantly with lining-layer hyperplasia as well as with inflammatory infiltration with macrophages, especially the CD163+ subset, and with PMNs. Accordingly, supervised clustering using these synovial parameters identified a cluster of 20 SpA patients with significantly higher disease activity, and this finding was confirmed in an independent SpA cohort. However, multiparameter models based on synovial histopathology were relatively poor predictors of disease activity in individual patients. In conclusion, these data indicate that inflammatory infiltration of the synovium with CD163+ macrophages and PMNs as well as lining-layer hyperplasia reflect global disease activity in SpA, independently of the SpA subtype

  18. The Influence of Solar Activity on the Rainfall over India: Cycle-to ...

    Indian Academy of Sciences (India)

    The Influence of Solar Activity on the Rainfall over India: Cycle-to-Cycle Variations. K. M. Hiremath. Indian Institute of Astrophysics, Bangalore 560 034, India. e-mail: hiremath@iiap.res.in. Abstract. We use 130 years data for studying correlative effects due to solar cycle and activity phenomena on the occurrence of rainfall ...

  19. Influence of sulphur dioxide on chlorophyll content and catalase activity in some chosen lichen species

    Energy Technology Data Exchange (ETDEWEB)

    Kuziel, S

    1974-01-01

    The influence of SO/sub 2/ on changes in catalase activity and in chlorophyll content were investigated under laboratory conditions in several lichen species and in maize. In all the plants examined the chlorophyll content and catalase activity decreased after treatment with SO/sub 2/ as compared with that in the control plants.

  20. A systematic review - physical activity in dementia: The influence of the nursing home environment

    NARCIS (Netherlands)

    Anderiesen, H.; Scherder, E.J.A.; Goossens, R.H.; Sonneveld, M.

    2014-01-01

    Most older persons with dementia living in nursing homes spend their days without engaging in much physical activity. This study therefore looked at the influence that the environment has on their level of physical activity, by reviewing empirical studies that measured the effects of environmental

  1. Self-Schemata for Movement Activities: The Influence of Race and Gender.

    Science.gov (United States)

    Harrison, Louis, Jr.; And Others

    This study investigated the influence of race and gender on students' self-schema for movement activities. Study participants were 168 male and female seventh- and eighth-grade students, both African American and Euro American, from a semi-rural school in a Southeastern state. The Physical Activity Schema Analysis (PASA) was administered to…

  2. Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A.

    Science.gov (United States)

    Sever-Chroneos, Zvjezdana; Krupa, Agnieszka; Davis, Jeremy; Hasan, Misbah; Yang, Ching-Hui; Szeliga, Jacek; Herrmann, Mathias; Hussain, Muzafar; Geisbrecht, Brian V; Kobzik, Lester; Chroneos, Zissis C

    2011-02-11

    Staphylococcus aureus causes life-threatening pneumonia in hospitals and deadly superinfection during viral influenza. The current study investigated the role of surfactant protein A (SP-A) in opsonization and clearance of S. aureus. Previous studies showed that SP-A mediates phagocytosis via the SP-A receptor 210 (SP-R210). Here, we show that SP-R210 mediates binding and control of SP-A-opsonized S. aureus by macrophages. We determined that SP-A binds S. aureus through the extracellular adhesin Eap. Consequently, SP-A enhanced macrophage uptake of Eap-expressing (Eap(+)) but not Eap-deficient (Eap(-)) S. aureus. In a reciprocal fashion, SP-A failed to enhance uptake of Eap(+) S. aureus in peritoneal Raw264.7 macrophages with a dominant negative mutation (SP-R210(DN)) blocking surface expression of SP-R210. Accordingly, WT mice cleared infection with Eap(+) but succumbed to sublethal infection with Eap- S. aureus. However, SP-R210(DN) cells compensated by increasing non-opsonic phagocytosis of Eap(+) S. aureus via the scavenger receptor scavenger receptor class A (SR-A), while non-opsonic uptake of Eap(-) S. aureus was impaired. Macrophages express two isoforms: SP-R210(L) and SP-R210(S). The results show that WT alveolar macrophages are distinguished by expression of SP-R210(L), whereas SR-A(-/-) alveolar macrophages are deficient in SP-R210(L) expressing only SP-R210(S). Accordingly, SR-A(-/-) mice were highly susceptible to both Eap(+) and Eap(-) S. aureus. The lungs of susceptible mice generated abnormal inflammatory responses that were associated with impaired killing and persistence of S. aureus infection in the lung. In conclusion, alveolar macrophage SP-R210(L) mediates recognition and killing of SP-A-opsonized S. aureus in vivo, coordinating inflammatory responses and resolution of S. aureus pneumonia through interaction with SR-A.

  3. Perceived influence of intrinsic/extrinsic factors on participation in life activities after spinal cord injury.

    Science.gov (United States)

    Cobb, John E; Leblond, Jean; Dumont, Frédéric S; Noreau, Luc

    2018-04-03

    Various types of limitations on community participation are experienced by people with spinal cord injury (SCI). To determine: 1) the perceived influence of six intrinsic/extrinsic factors (i.e. physical impairment, emotional condition, thinking skills, environment, lack of assistance, discrimination) on participation in 26 life activities, 2) if this influence varied based on extent of participation, and 3) if personal or environmental characteristics influenced perceptions. Secondary analysis of a cohort (SCI Community Survey, n = 1508) using the SCI Person-Perceived Participation in Daily Activities Questionnaire. Frequency tables, Fisher's exact tests and correspondence analyses. Respectively, 79.6% and 38.5% of respondents perceived that their physical impairment and the natural and/or built environment were the main factors that limited participation across all activities. Considering participation between three groups (no participation; less than wanted; as much as wanted), significant differences (p intrinsic/extrinsic factors on participation was not significantly influenced by other personal or environmental characteristics. A majority of people with SCI perceived that their participation is limited by one or more of intrinsic/extrinsic factors. Perceptions regarding which factors influence participation differ between activities and these perceptions appear related to the extent of participation suggesting that those who actively participate could be the most sensitive to limitations in certain activities. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. [Adsorbent effect of activated carbon on small molecular uremic toxin and its influence factors].

    Science.gov (United States)

    Yang, Bo; Jiang, Yun-sheng; Li, Jun

    2003-06-01

    To analyze the adsorbent effect of activated carbon on uremic toxin and its influence factors. Uremic toxins (urea, creatinine and uric acid) were dissolved in the distilled water to obtain uremic toxic solution. Activated carbon was added to the solution, and the concentrations of uremic toxins were measured at different time spots. To determine the influence factors, some possible related materials, such as bile, amino acid, Ringer's, solution of glucose, HCl or NaOH respectively were added simultaneously. The concentrations of toxins in uremic toxic solution decreased 5 min after adding the activated carbon. The concentration of urea was the lowest at 30 min, but it increased after 50 min; while the concentrations of creatinine and uric acid reached the lowest level from 10 to 30 min after adding the activated carbon, and maintained at the same level after that. The bile, amino acid, electrolyte, glucose and pH value did not influence the adsorption of uric acid significantly, but they influenced the adsorption of urea and creatinine. Bile and amino acid influenced the concentration of urea remarkably, following glucose, NaOH and HCl. The effect of pH 2.0 solution on the creatinine concentration was the most significant, following glucose. Activated carbon has adsorptive effect on uremic toxins, but its adsorptive effect decreases as time goes on. Bile, glucose, amino acid, NaOH and HCl can affect the adsorptive effect of activated carbon on uremic toxins to some extent.

  5. Genetic and environmental influences on the allocation of adolescent leisure time activities.

    Science.gov (United States)

    Haberstick, Brett C; Zeiger, Joanna S; Corley, Robin P

    2014-01-01

    There is a growing recognition of the importance of the out-of-school activities in which adolescents choose to participate. Youth activities vary widely in terms of specific activities and in time devoted to them but can generally be grouped by the type and total duration spent per type. We collected leisure time information using a 17-item leisure time questionnaire in a large sample of same- and opposite-sex adolescent twin pairs (N = 2847). Using both univariate and multivariate genetic models, we sought to determine the type and magnitude of genetic and environmental influences on the allocation of time toward different leisure times. Results indicated that both genetic and shared and nonshared environmental influences were important contributors to individual differences in physical, social, intellectual, family, and passive activities such as watching television. The magnitude of these influences differed between males and females. Environmental influences were the primary factors contributing to the covariation of different leisure time activities. Our results suggest the importance of heritable influences on the allocation of leisure time activity by adolescents and highlight the importance of environmental experiences in these choices.

  6. Measuring the Effects of Forest SPA Programme in Urban Parks Using Active Imagination

    Directory of Open Access Journals (Sweden)

    Pešalj Gordana

    2016-12-01

    Full Text Available Nature has been shown to be beneficial to our overall health and well-being. We are all connected to nature and it is important to maintain this vital connection for our health and well-being. Spending time outside in nature or urban parks has been shown to positively affect a person’s emotions and improve their sense of well-being. Access to nature balances circadian rhythms, lowers blood pressure, reduces stress and increases absorption of Vitamin D. Increasingly, evidence demonstrates that contactwith the living world around us is an important part of healing and recovery. The natural world’s role in human well-being is an essential, yet often forgotten, aspect of healthcare. Of particular importance are the benefits one can derive through interaction with natural environments. Reincorporating the natural world is practiced to move healthcare toward being more “green”. Spiritual well-being is enhanced through the experience of greater interconnections, and it occurs when interacting with the natural world. One study examined the physiological and psychological responses to real forest landscapes as well as the therapeutic uses of forests relative to urban environments.

  7. The detailed analysis of natural radionuclides dissolved in spa waters of the Kłodzko Valley, Sudety Mountains, Poland

    International Nuclear Information System (INIS)

    Walencik-Łata, A.; Kozłowska, B.; Dorda, J.; Przylibski, T.A.

    2016-01-01

    A survey was conducted to measure natural radioactivity in spa waters from the Kłodzko Valley. The main goal of this study was to determine the activity concentration of uranium, radium and radon isotopes in the investigated groundwaters. Samples were collected several times from 35 water intakes from 5 spas and 2 mineral water bottling plants. The authors examined whether the increased gamma radiation background, as well as the elevated values of radium and uranium content in reservoir rocks, have a significant impact on the natural radioactivity of these waters. The second objective of this research was to provide information about geochemistry of U, Ra, Rn radionuclides and the radiological and chemical risks incurred by ingestion of isotopes with drinking water. On the basis of results obtained, it is feasible to assess the health hazard posed by ingestion of natural radioactivity with drinking waters. Moreover, the data yielded by this research may be helpful in the process of verification of the application of these waters in balneotherapy. In addition, annual effective radiation doses resulting from the isotopes consumption were calculated on the basis of the evaluated activity concentrations. In dose assessment for uranium and radium isotopes, the authors provided values for different human age groups. The obtained uranium content in the investigated waters was compared with the currently valid regulations concerning the quality of drinking water. Based on the activity concentrations data, the activity isotopic ratios 234 U/ 238 U, 226 Ra/ 238 U, 222 Rn/ 238 U, 222 Rn/ 226 Ra and the correlations between radionuclides content were then examined. In brief, it may be concluded on the basis of the obtained results that radon solubility is inversely proportional to radium and uranium dissolution in environmental water circulation. The presented study allows conclusions to be drawn on the radionuclide circulation among different environmental biota: from

  8. The detailed analysis of natural radionuclides dissolved in spa waters of the Kłodzko Valley, Sudety Mountains, Poland

    Energy Technology Data Exchange (ETDEWEB)

    Walencik-Łata, A., E-mail: agata.walencik@us.edu.pl [University of Silesia, Institute of Physics, Department of Nuclear Physics and Its Applications, Uniwersytecka 4 St., 40-007 Katowice (Poland); Kozłowska, B.; Dorda, J. [University of Silesia, Institute of Physics, Department of Nuclear Physics and Its Applications, Uniwersytecka 4 St., 40-007 Katowice (Poland); Przylibski, T.A. [Wrocław University of Technology, Faculty of Geoengineering, Mining and Geology, Division of Geology and Mineral Waters, Wybrzeże S. Wyspiańskiego 27, 50-370 Wrocław (Poland)

    2016-11-01

    A survey was conducted to measure natural radioactivity in spa waters from the Kłodzko Valley. The main goal of this study was to determine the activity concentration of uranium, radium and radon isotopes in the investigated groundwaters. Samples were collected several times from 35 water intakes from 5 spas and 2 mineral water bottling plants. The authors examined whether the increased gamma radiation background, as well as the elevated values of radium and uranium content in reservoir rocks, have a significant impact on the natural radioactivity of these waters. The second objective of this research was to provide information about geochemistry of U, Ra, Rn radionuclides and the radiological and chemical risks incurred by ingestion of isotopes with drinking water. On the basis of results obtained, it is feasible to assess the health hazard posed by ingestion of natural radioactivity with drinking waters. Moreover, the data yielded by this research may be helpful in the process of verification of the application of these waters in balneotherapy. In addition, annual effective radiation doses resulting from the isotopes consumption were calculated on the basis of the evaluated activity concentrations. In dose assessment for uranium and radium isotopes, the authors provided values for different human age groups. The obtained uranium content in the investigated waters was compared with the currently valid regulations concerning the quality of drinking water. Based on the activity concentrations data, the activity isotopic ratios {sup 234}U/{sup 238}U, {sup 226}Ra/{sup 238}U, {sup 222}Rn/{sup 238}U, {sup 222}Rn/{sup 226}Ra and the correlations between radionuclides content were then examined. In brief, it may be concluded on the basis of the obtained results that radon solubility is inversely proportional to radium and uranium dissolution in environmental water circulation. The presented study allows conclusions to be drawn on the radionuclide circulation among

  9. Real-life effectiveness of spa therapy in rheumatic and musculoskeletal diseases: a retrospective study of 819 patients

    Science.gov (United States)

    Karagülle, Mine; Kardeş, Sinan; Karagülle, Müfit Zeki

    2017-11-01

    The objective of this study is to determine the use and efficacy of spa therapy in patients with a wide spectrum of rheumatic and musculoskeletal diseases under real-life clinical practice circumstances. In this retrospective observational study at the Medical Ecology and Hydroclimatology Department of Istanbul Faculty of Medicine, the records of all adult patients with rheumatic and musculoskeletal diseases who were prescribed a spa therapy in various health resorts in Turkey between 2002 and 2012 were analyzed. Patients sojourned to and stayed at a health resort and followed a usual 2-week course of spa therapy. The patients were examined within a week before and after the spa therapy at the department by the physicians and outcome measures were pain intensity (visual analog scale, VAS), patient's general evaluation (VAS), physician's general evaluation (VAS), Health Assessment Questionnaire (HAQ), Lequesne's Functional Index (LFI), Western Ontario and McMaster Universities Index (WOMAC), Waddell Index (WI), Neck Pain and Disability Scale (NPDS), Shoulder Disability Questionnaire (SDQ), Fibromyalgia Impact Questionnaire (FIQ), and Beck's Depression Inventory (BDI). In total, 819 patients were included in the analysis. The diagnoses were 536 osteoarthritis; 115 fibromyalgia; 50 lumbar disc herniation; 34 cervical disc herniation; 23 nonspecific low back pain; 22 ankylosing spondylitis; 16 rheumatoid arthritis; 9 rotator cuff tendinitis; and 14 other conditions/diseases including scoliosis, stenosing flexor tenosynovitis, congenital hip dislocation in adult, Behçet's disease, de Quervain tendinopathy, psoriatic arthritis, osteoporosis, fracture rehabilitation, and diffuse idiopathic skeletal hyperostosis. Statistically significant decrease in pain scores was found in all patients except hip osteoarthritis ( p = 0.063) and rheumatoid arthritis ( p = 0.134) subgroups; and statistically significant improvement in function in all patients except hip osteoarthritis ( p

  10. Diagnostics of the Factors Influencing the Export Activity of an Enterprise

    Directory of Open Access Journals (Sweden)

    Skrynkovskyy Ruslan M.

    2017-09-01

    Full Text Available The modern practice of doing business proves that a successful entrance of any enterprise to external (international markets depends on the level of its readiness for carrying out foreign economic activity. Under such circumstances, the process of targeted analysis and assessment of factors influencing the export activity of the enterprise is relevant, expedient and important. The aim of the article is the formation and development of theoretical and methodological bases for diagnosing factors influencing the export activity of an enterprise on the basis of theory and practice in the field of management and administration. It is found that the diagnostics should be understood as the process of identification, analysis and evaluation of influence (functional, dysfunctional of the factors (circumstances, conditions, etc. on the export activity of an enterprise in order to identify and solve problems (current, possible ones in the sphere of supply and implementation of specific actions (steps related to its entrance to external (international markets. It is determined that the key business indicators of the system for diagnosing the factors influencing the export activity of an enterprise are indicators reflecting the influence of the main factors on its export activity: level of fulfillment of obligations in terms of cost; level of conclusion of “expensive contracts”; share of renewed business contracts in the total number of contracts; level of satisfaction of claims; level of delivery variability. The prospect for further research in this scientific direction is developing a system of partial diagnostic goals of the integrated system of goals for conducting economic diagnostics of enterprises taking into account the diagnostics of factors influencing the export activity of an enterprise as a partial diagnostic goal.

  11. Environmental influences on physical activity in rural Midwestern adults: a qualitative approach.

    Science.gov (United States)

    Chrisman, Matthew; Nothwehr, Faryle; Yang, Ginger; Oleson, Jacob

    2015-01-01

    Qualitative research can be used to examine multiple factors associated with physical activity and help practitioners identify language used by the rural adult population when discussing this behavior. Three focus groups were conducted among 19 residents of multiple towns in a rural Midwestern county to examine the language and influences on rural physical activity. Focus group members were asked to define physical activity, exercise, community, and neighborhood. They were asked about the activities they engaged in and facilitators and barriers to those activities. A guidebook was developed to capture major themes and common patterns that emerged in the responses to the topics discussed. The data were reviewed for repeated statements and points that were agreed on by multiple participants. Important factors associated with physical activity include the importance of social support and modeling physical activity behavior. Also, the influence of pets and children was important for engaging these adults in physical activity. The focus group members engaged in walking and bicycling in their neighborhood streets and community trails, and desired to see community buildings be open to the public for exercise. This study revealed contextual issues and culturally relevant language for practitioners to use in tailoring physical activity measurement tools or designing interventions for a rural adult population. Social support (specifically, seeing others being active and using pets as motivators for being active) and policy attitudes may be targeted for interventions to increase physical activity in rural adults. © 2014 Society for Public Health Education.

  12. Influence of Friends on Children’s Physical Activity: A Review

    Science.gov (United States)

    Maturo, Claire C.

    2013-01-01

    We examined evidence for friendship influences on children's physical activity (PA) through systematic searches of online databases in May 2012. We identified 106 studies (25 qualitative) published in English since 2000 that analyzed indicators of friendship influences (e.g., communication about PA, friends’ PA, and PA with friends) among persons younger than 19 years. Children's PA was positively associated with encouragement from friends (43 of 55 studies indicating a positive relationship), friends' own PA (30/35), and engagement with friends in PA (9/10). These findings are consistent with friends influencing PA, but most studies did not isolate influence from other factors that could explain similarity. Understanding friendship influences in childhood can facilitate the promotion of lifelong healthy habits. PA with friends should be considered in health promotion programs. PMID:23678914

  13. Physical activity, evaluation of menopause, life satisfaction and influence tactics in marriage of perimenopausal women

    Directory of Open Access Journals (Sweden)

    Eugenia Mandal

    2016-10-01

    Full Text Available Background Domination of the biomedical approach to menopause may imply creation of negative attitudes to the phenomenon, and at the same time negatively affect women’s life satisfaction and behaviour in the family. It is assumed that physical activity may be a defensive factor, as this type of activity may reduce the intensity of menopause symptoms. The aim of the research was to determine the relation between menopause evaluation, life satisfaction and tactics of influence employed in marriage by women who differ in involvement in physical exercise. Participants and procedure The research was conducted among 90 women, at the age of 45-55: 45 physically active women and 45 women who do not engage in any physical activity. The following research methods were used: the Menopause Evaluation Scale, the Satisfaction With Life Scale (SWLS and the Questionnaire of Influence in Close Relations of Women and Men. Results Positive evaluation of menopause was related to involvement in physical exercise as well as to a stronger tendency to use positive strategies of exerting influence on one’s spouse. The research also showed a slight correlation between life satisfaction and involvement in physical exercise. Negative evaluation of menopause was related to avoiding physical activity. Conclusions Physical activity is more frequently related to a positive attitude towards menopause and the use of more positive tactics of exerting influence on one’s spouse, and slightly positively conducive to one’s life satisfaction level.

  14. Genotypic and climatic influence on the antioxidant activity of flavonoids in Kale (Brassica oleracea var. sabellica).

    Science.gov (United States)

    Zietz, Michaela; Weckmüller, Annika; Schmidt, Susanne; Rohn, Sascha; Schreiner, Monika; Krumbein, Angelika; Kroh, Lothar W

    2010-02-24

    The influence of genotype and climatic factors, e.g. mean temperature and mean global radiation level, on the antioxidant activity of kale was investigated. Therefore, eight kale cultivars, hybrid and traditional, old cultivars, were grown in a field experiment and harvested at four different times. In addition to the investigation of the total phenolic content, the overall antioxidant activity was determined by TEAC assay and electron spin resonance spectrometry. A special aim was to characterize the contribution of single flavonoids to the overall antioxidant activity using an HPLC-online TEAC approach. The antioxidant activity and the total phenolic content were influenced by the genotype and the eco-physiological factors. The HPLC-online TEAC results showed that not all flavonol glycosides contribute to the overall antioxidant activity in the same manner. Taking the results of the structural analysis obtained by HPLC-ESI-MS(n) into account, distinct structure-antioxidant relationships have been observed.

  15. Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring the spaCBA Pili Cluster in Lactobacillus casei LOCK 0919

    Czech Academy of Sciences Publication Activity Database

    Aleksandrzak-Piekarczyk, T.; Koryszewska-Baginska, A.; Grynberg, M.; Nowak, A.; Cukrowska, B.; Kozáková, Hana; Bardowski, J.

    2016-01-01

    Roč. 8, č. 1 (2016), s. 202-217 ISSN 1759-6653 Institutional support: RVO:61388971 Keywords : adhesion * spaCBA pilus cluster * lactobacillus Subject RIV: EC - Immunology Impact factor: 3.979, year: 2016

  16. Spa therapy (balneotherapy) relieves mental stress, sleep disorder, and general health problems in sub-healthy people

    Science.gov (United States)

    Yang, Bei; Qin, Qi-zhong; Han, Ling-li; Lin, Jing; Chen, Yu

    2018-02-01

    To investigate the relieving effects of hot spring balneotherapy on mental stress, sleep disorder, general health problems, and women's health problems in sub-healthy people, we recruited 500 volunteers in sub-health in Chongqing, and 362 volunteers completed the project, including 223 in the intervention group and 139 in the control group. The intervention group underwent hot spring balneotherapy for 5 months, while the control group did not. The two groups took questionnaire investigation (general data, mental stress, emotional status, sleep quality, general health problems, as well as some women's health problems) and physical examination (height, weight, waist circumference, blood pressure, blood lipid, blood sugar) 5 months before and after the intervention, respectively. After intervention, sleep disorder (difficulty in falling asleep ( P = 0.017); dreaminess, nightmare suffering, and restless sleep ( P = 0.013); easy awakening ( P = 0.003) and difficulty in falling into sleep again after awakening( P = 0.016); and mental stress ( P = 0.031) and problems of general health (head pain ( P = 0.026), joint pain( P = 0.009), leg or foot cramps ( P = 0.001), blurred vision ( P = 0.009)) were relieved significantly in the intervention group, as compared with the control group. While other indicators (fatigue, eye tiredness, limb numbness, constipation, skin allergy) and women's health problems (breast distending pain; dysmenorrhea, irregular menstruation) were relieved significantly in the self-comparison of the intervention group before and after intervention ( P 0.05). All indications (except bad mood, low mood, and worry or irritability) in the intervention group significantly improved, with effect size from 0.096 to 1.302. Multiple logistic regression analysis showed that the frequency, length, and location of balneotherapy in the intervention group were the factors influencing emotion, sleep, and health condition ( P Physical examination found that waist

  17. Social influence and adolescent health-related physical activity in structured and unstructured settings: role of channel and type.

    Science.gov (United States)

    Spink, Kevin S; Wilson, Kathleen S; Ulvick, Jocelyn

    2012-08-01

    Social influence channels (e.g., parents) and types (e.g., compliance) have each been related to physical activity independently, but little is known about how these two categories of influence may operate in combination. This study examined the relationships between various combinations of social influence and physical activity among youth across structured and unstructured settings. Adolescents (N=304), classified as high or low active, reported the social influence combinations they received for being active. Participants identified three channels and three types of influence associated with being active. For structured activity, compliance with peers and significant others predicted membership in the high active group (values of psocial influence, when examining health-related physical activity.

  18. Features of influence of sports activities on the identity of students

    Directory of Open Access Journals (Sweden)

    Sutula Vasilij

    2017-02-01

    Full Text Available Purpose: the definition of features of influence of sports activities on the identity of sportsmen. Material & Methods: the special surveys of students and teachers of KhSAPC, and also students, who train in sports club "Politekhnik", and the students who are engaged in sports sections NLA were conducted for the solution of purposes. Results: the most important qualities of the personality which sports activities influence are: formation of "confidence", "emotional stability", and "orientation to achievement" at sportsmen. According to most of the interviewed sportsmen and experts, the authority of the coach is not significant factor which influences the identity of sportsmen. Conclusions: it is established as a result of the conducted researches that sports activities most of all influence the formation of confidence, emotional stability and orientation to achievement at sportsmen. Results of the research demonstrate also that the identity of the sportsman is most influenced by the competitive relationship which develops in the course of competitive activity. Results of the research also indicate disturbing tendency which is shown that most of sportsmen connect the end of their sports career with injuries.

  19. Longitudinal examination of social and environmental influences on motivation for physical activity.

    Science.gov (United States)

    Richards, Elizabeth A; McDonough, Meghan; Fu, Rong

    2017-10-01

    Physical activity behavior is influenced by numerous factors including motivation, social interactions, and the walkability of the environment. To examine how social contexts and environmental features affect physical activity motivational processes across time. Participants (N=104) completed 3 monthly online surveys assessing self-determination theory constructs, social partners in physical activity, neighborhood walkability, and weekly physical activity. Longitudinal path analysis examined the degree to which physical activity was predicted by individual goals, orientation, and autonomy support and whether these associations were meditated by motivation and moderated by the social and environmental contexts of physical activity. The effect of controlled exercise orientations on physical activity was mediated by autonomous motivation. This association was stronger among those who perceived less crime in their neighborhoods. To improve the ability to tailor physical activity counseling it is important to understand how each person views exercise situations and to understand his/her social and neighborhood environments. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Growth and extracellular phosphatase activity of arbuscular mycorrhizal hyphae as influenced by soil organic matter

    DEFF Research Database (Denmark)

    Joner, E.J.; Jakobsen, I.

    1995-01-01

    Two experiments were set up to investigate the influence of soil organic matter on growth of arbuscular mycorrhizal (AM) hyphae and concurrent changes in soil inorganic P, organic P and phosphatase activity. A sandy loam soil was kept for 14 months under two regimes (outdoor where surplus...... additions. In soil with added clover alkaline phosphatase activity increased due to the presence of mycorrhizal hyphae. We suggest that mycorrhizas may influence the exudation of acid phosphatase by roots. Hyphae of G. invermaium did apparently not excrete extracellular phosphatases, but their presence may...

  1. Familial influences on the full range of variability in attention and activity levels during adolescence: A longitudinal twin study.

    Science.gov (United States)

    Peng, Chun-Zi; Grant, Julia D; Heath, Andrew C; Reiersen, Angela M; Mulligan, Richard C; Anokhin, Andrey P

    2016-05-01

    To investigate familial influences on the full range of variability in attention and activity across adolescence, we collected maternal ratings of 339 twin pairs at ages 12, 14, and 16, and estimated the transmitted and new familial influences on attention and activity as measured by the Strengths and Weaknesses of Attention-Deficit/Hyperactivity Disorder Symptoms and Normal Behavior Scale. Familial influences were substantial for both traits across adolescence: genetic influences accounted for 54%-73% (attention) and 31%-73% (activity) of the total variance, and shared environmental influences accounted for 0%-22% of the attention variance and 13%-57% of the activity variance. The longitudinal stability of individual differences in attention and activity was largely accounted for by familial influences transmitted from previous ages. Innovations over adolescence were also partially attributable to familial influences. Studying the full range of variability in attention and activity may facilitate our understanding of attention-deficit/hyperactivity disorder's etiology and intervention.

  2. Diagnosis of the socionic temperament of personality and creating a psychological portrait of the Western European SPA and wellness tourists in Bulgaria

    Science.gov (United States)

    Stoyanova, Milena

    2017-03-01

    Human personality is a set of psychological characteristics that distinguishes it from others. However people can be classified as congenital personality types, interactions that are precisely defined. The aim of this article is to characterize the socionic temperament and psychological profile of the spa and wellness tourists in Bulgaria. The study is based on a survey of 460 tourists who visited Bulgarian spa centers in the summer and autumn of 2015.

  3. Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

    Directory of Open Access Journals (Sweden)

    Parisa Asadollahi

    2018-02-01

    Full Text Available Background:Staphylococcus aureus, a leading cause of community-acquired and nosocomial infections, remains a major health problem worldwide. Molecular typing methods, such as spa typing, are vital for the control and, when typing can be made more timely, prevention of S. aureus spread around healthcare settings. The current study aims to review the literature to report the most common clinical spa types around the world, which is important for epidemiological surveys and nosocomial infection control policies.Methods: A search via PubMed, Google Scholar, Web of Science, Embase, the Cochrane library, and Scopus was conducted for original articles reporting the most prevalent spa types among S. aureus isolates. The search terms were “Staphylococcus aureus, spa typing.”Results: The most prevalent spa types were t032, t008 and t002 in Europe; t037 and t002 in Asia; t008, t002, and t242 in America; t037, t084, and t064 in Africa; and t020 in Australia. In Europe, all the isolates related to spa type t032 were MRSA. In addition, spa type t037 in Africa and t037and t437 in Australia also consisted exclusively of MRSA isolates. Given the fact that more than 95% of the papers we studied originated in the past decade there was no option to study the dynamics of regional clone emergence.Conclusion: This review documents the presence of the most prevalent spa types in countries, continents and worldwide and shows big local differences in clonal distribution.

  4. Evaluasi Hasil Implementasi the Coordinated Mekong Ministerial Initiative Against Trafficking Sub-regional Plan of Action (Commit Spa) Dalam Menangani Human Trafficking Di Thailand Periode 2011-2013

    OpenAIRE

    Rahmahwati, Isti Nur; Windiani, Reni; Putranti, Ika Riswanti

    2015-01-01

    Thailand, Laos, Myanmar, China, Vietnam, and Cambodia createdCOMMIT and COMMIT SPA. During COMMIT SPAimplementation period 2011-2013, the number of human traffickingincreased in Thailand. Most of human trafficking victims in Thailandare exploited into sexual exploitation and forced labor. The studyaims to analyze causes of human trafficking increased duringCOMMIT SPA implementation. The study result is the increase ofhuman trafficking is caused by Thailand's interests by using sextrafficking ...

  5. [The impact of the spa therapy on reduction of the perception of pain intensity in patients with degenerative joints and disc disease].

    Science.gov (United States)

    Kuciel-Lewandowska, Jadwiga; Paprocka-Borowicz, Małgorzata

    2015-01-01

    Degenerative joints and disc disease is accompanied by chronic pain which is the main symptom of the disease. Medical spa therapy has the task of providing comprehensive treatment embracing diseases of limbs as well as other systems and the essential role of medical treatment, in particular spa therapy, is pain relief. The aim of the study was to evaluate the effect of the spa treatment on the level of pain perception in patients with degenerative joints and disc disease. The observation embraced 120 people with degenerative joints and disc disease treated in the spa. The study included a comprehensive therapy conducted over a 21-day stays at the spa Przerzeczyn-Zdrój with the application of selected physical treatments, physiotherapy and the use of therapeutic natural resources: peloid mud and healing radon-sulphide water. Moreover, there was psychological counseling and health education conducted. The study also included observation of 21 persons from the control group. However, the patients in the control group did not benefit from balneotherapy, psychological care and education. There was a standard VAS scale for pain and non-standard questionnaire of pain assessment constructed for the study purposes. The assessment of pain using the VAS scale and questionnaire of pain assessment both in the study group and the control group were performed before and after the treatment. The results were analyzed statistically, there was Statistica program in Polish version used. In the analysis of the obtained results there were two tests scheduled: the sign test, the Wilcoxon test and descriptive statistics. As a result of the spa therapy and treatments administered on an outpatient basis there was reduction of pain intensity observed. 1. Spa therapy and outpatient treatment reduce the level of pain in patients with degenerative joints and disc disease. 2. The reduction of pain level was more effective in case of therapy conducted in the spa.

  6. The rSPA Processes of River Water-quality Analysis System for Critical Contaminate Detection, Classification Multiple-water-quality-parameter Values and Real-time Notification

    OpenAIRE

    Chalisa VEESOMMAI; Yasushi KIYOKI

    2016-01-01

    The water quality analysis is one of the most important aspects of designing environmental systems. It is necessary to realize detection and classification processes and systems for water quality analysis. The important direction is to lead to uncomplicated understanding for public utilization. This paper presents the river Sensing Processing Actuation processes (rSPA) for determination and classification of multiple-water- parameters in Chaophraya river. According to rSPA processes of multip...

  7. State-wide surveillance of antibiotic resistance patterns and spa types of methicillin-resistant Staphylococcus aureus from blood cultures in North Rhine-Westphalia, 2011-2013.

    Science.gov (United States)

    Cuny, C; Layer, F; Werner, G; Harmsen, D; Daniels-Haardt, I; Jurke, A; Mellmann, A; Witte, W; Köck, R

    2015-08-01

    Methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of bacteraemia. We aimed to obtain a complete picture of severe MRSA infections by characterizing all MRSA isolates from bloodstream infections in the largest German federal state (North Rhine-Westphalia, 18 million inhabitants) using S. aureus protein A (spa) sequence-typing and antimicrobial susceptibility testing. MRSA isolates (n = 1952) were collected prospectively (2011-2013) and spa-typed. Among 181 different spa types, t003 (n = 746 isolates; 38.2%) and t032 (n = 594; 30.4%) were predominant. Analysis of the geographical occurrence of spa clonal complexes (spa-CCs) and spa types revealed divergent distribution between federal state districts for spa-CCs 003 (p resistant to fluoroquinolones, 78% to erythromycin, 70% to clindamycin, 4% to gentamicin, 2% to rifampicin, 0.4% to daptomycin, 0.1% to linezolid and 0% to vancomycin, respectively. Vancomycin MICs of 2 mg/L involved 0.5% of the isolates. In conclusion, the detection of regional molecular clusters added valuable information for epidemiological case tracing and allowed conclusions to be reached on the importance of newly emerging MRSA reservoirs, such as livestock (spa-CC011), for MRSA bacteraemia in some parts of the federal state. Susceptibility testing revealed broad resistance to substances used for oral treatment, but demonstrated that those antibiotics that are mostly applied for treatment of MRSA bacteraemia and important combination partners were highly susceptible. Copyright © 2015 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  8. Distribution of the Most Prevalent Spa Types among Clinical Isolates of Methicillin-Resistant and -Susceptible Staphylococcus aureus around the World: A Review

    Science.gov (United States)

    Asadollahi, Parisa; Farahani, Narges Nodeh; Mirzaii, Mehdi; Khoramrooz, Seyed Sajjad; van Belkum, Alex; Asadollahi, Khairollah; Dadashi, Masoud; Darban-Sarokhalil, Davood

    2018-01-01

    Background: Staphylococcus aureus, a leading cause of community-acquired and nosocomial infections, remains a major health problem worldwide. Molecular typing methods, such as spa typing, are vital for the control and, when typing can be made more timely, prevention of S. aureus spread around healthcare settings. The current study aims to review the literature to report the most common clinical spa types around the world, which is important for epidemiological surveys and nosocomial infection control policies. Methods: A search via PubMed, Google Scholar, Web of Science, Embase, the Cochrane library, and Scopus was conducted for original articles reporting the most prevalent spa types among S. aureus isolates. The search terms were “Staphylococcus aureus, spa typing.” Results: The most prevalent spa types were t032, t008 and t002 in Europe; t037 and t002 in Asia; t008, t002, and t242 in America; t037, t084, and t064 in Africa; and t020 in Australia. In Europe, all the isolates related to spa type t032 were MRSA. In addition, spa type t037 in Africa and t037and t437 in Australia also consisted exclusively of MRSA isolates. Given the fact that more than 95% of the papers we studied originated in the past decade there was no option to study the dynamics of regional clone emergence. Conclusion: This review documents the presence of the most prevalent spa types in countries, continents and worldwide and shows big local differences in clonal distribution. PMID:29487578

  9. Analisa Pengaruh Brand Image Terhadap Customer Loyalty Dengan Customer Satisfaction Sebagai Mediator Pada the Dreamland Luxury Villas and Spa, Bali.

    OpenAIRE

    Leliga, Felicia Juliani

    2013-01-01

    Penelitian ini dilakukan untuk mengetahui customer loyalty pada brand The Dreamland Luxury Villas and Spa, Bali melalui penilaian responden terhadap dimensi brand image yang terdiri dari brand strength, brand favorability, dan brand uniqueness, dengan menggunakan customer satisfaction sebagai variabel mediator. Dalam penelitian ini, penulis menggunakan metode kuantitatif dengan teknik partial least square (PLS). Dari hasil analisa, disimpulkan bahwa tidak ada pengaruh brand strength dan brand...

  10. The Present and Future of Szigetvár Spa – An Economic Analysis of Geothermal Energy Investment

    Directory of Open Access Journals (Sweden)

    Judit Pálné Schreiner

    2014-09-01

    Full Text Available In Hungary, geothermal energy has proved to be an economical source of energy for direct use. It highlights the pros and cons of including renewable energy in the power generation mix of Hungary, and the pros and cons of local application. This paper looks at the operation of Szigetvár Spa from both economic and social aspects. In this study, qualitative analysis is used for the basic economic and social introduction of the Spa, and then real options, based on quantitative methods, are described to identify the long-term financial consequences of the project. In 1966, thermal water was found in Szigetvár. In 1997, this thermal water was certified as medicinal water. The wellhead temperature of Szigetvár thermal water is 62°C in the 790 metres deep thermal well. It is used as so-called domestic hot water in the Szent István housing estate and in Szigetvár Spa. One of the problems with the project is that it is based on single stage thermal water utilization, another problem is that the waste water is too hot. This can be solved by exploiting the heat energy of thermal water more intensively. This way, maximum benefits can be gained from geothermal energy with minimum use of energy. Static and dynamic investment analyses were carried out to examine the spa from a financial aspect. The methods used include static payback period, average rate of return, levelized cost of electricity, net present value, profitability index, dynamic payback period, internal rate of return and real options. By pricing geothermal technology, it is possible to identify the strategic value of flexibility, to quantify what was previously left unquantified, and thus to show that geothermal investments are profitable not only from a social but also from a financial aspect as well.

  11. [Marketing macroenvironment of a sanatorium and spa facility as a study object and a factor of strategic decision making].

    Science.gov (United States)

    Babaskin, D V

    2009-01-01

    Analysis of marketing macroenvironment is an important stage in the formulation of the strategy for the development and operation of a therapeutic and preventive healthcare facility making possible rapid adjustment to sharply changing marketing conditions. The possibility of using expert evaluation for the analysis of the marketing macroenvironment of a sanatorium and spa facility and a concrete medical care service provided (peloidotherapy) is illustrated. The study covers five aspects of marketing macroenvironment, viz. socio-demographic, technological, economic, political and ecological.

  12. Impact of serum SP-A and SP-D levels on comparison and prognosis of idiopathic pulmonary fibrosis

    OpenAIRE

    Wang, Kai; Ju, Qing; Cao, Jing; Tang, Wenze; Zhang, Jian

    2017-01-01

    Abstract Background and objective: Idiopathic pulmonary fibrosis (IPF) has a poor prognosis in general; however, it is heterogeneous to detect relative biomarkers for predicting the disease progression. Serum biomarkers can be conveniently collected to detect and help to differentially diagnose IPF and predict IPF prognosis. This meta-analysis aimed to evaluate the use of serum surfactant proteins A and D (SP-A and SP-D) for differential diagnosis and prognosis of IPF. Methods: Relevant artic...

  13. On the influence of the alternation of two different cooling systems on dairy cow daily activities

    Directory of Open Access Journals (Sweden)

    Simona M.C. Porto

    2017-02-01

    Full Text Available Among the causes that influence cow welfare, heat stress induced by microclimatic conditions is one of the most relevant and many studies have investigated the efficacy of different cooling systems on animal health status. Nevertheless, the direct influence of the cooling systems on possible modifications of dairy cow behaviour has been addressed in a few studies and the related results were affected by the presence of a paddock, which gave a refuge from hot temperature. Since an alteration of the daily time budget spent by dairy cows in their usual activities can be associated with changes in their health status, this study investigated the effects of the alternation of two different cooling systems on lying, standing, and feeding behaviour of a group of dairy cows bred in a free-stall dairy house where animals had no access to a paddock. The barn was equipped with a fogging system associated with forced ventilation installed in the resting area and a sprinkler system associated with forced ventilation installed in the feeding area. The two systems were activated alternately. The results demonstrated that the management of the two cooling systems affected the analysed behaviours. Though the activation of the cooling system installed in the resting area encouraged the decubitus of animals in the stalls, the activation of that one of the feeding alley could not be able to influence the standing behaviour and had only a moderate positive influence on the feeding activity.

  14. The Influence of the Characteristics of Mathematical Outdoor Activities in Mobile Environments on Students' Emotions

    Directory of Open Access Journals (Sweden)

    Wajeeh M. Daher

    2012-04-01

    Full Text Available This research attempted to find out how the characteristics of outdoor activities carried out with the mobile phone influence students' emotions. The research findings point at the following components related to the activity as influencing students' emotions: The activity novelty, the activity theme (related to everyday life, related to a new subject related to the students themselves or to an issue or a subject that the students like to do, etc., the activity conditions (its physical part is easy/uneasy to perform, resources are available, etc., the outer environment conditions (hot, warm, cold, etc., the roles which the activity enables (these roles may or may not satisfy a student, the learning method enabled in the activity (exploring mathematical ideas independently, exploring mathematics collaboratively, etc., the challenge or competition associated with the activity (it needs persistence, attention, etc.. These components show that taking care of students' leaning emotions in outdoor mathematical activities can be achieved through paying attention to different aspects of the activity which are outlined above.

  15. Adsorption of phenol by activated carbon: Influence of activation methods and solution pH

    International Nuclear Information System (INIS)

    Beker, Ulker; Ganbold, Batchimeg; Dertli, Halil; Guelbayir, Dilek Duranoglu

    2010-01-01

    Cherry stone based activated carbon derived from a canning industry was evaluated for its ability to remove phenol from an aqueous solution in a batch process. A comparative adsorption on the uptake of phenol by using commercial activated carbon (Chemviron CPG-LF), and two non-functional commercial polymeric adsorbents (MN-200 and XAD-2) containing a styrene-divinylbenzene macroporous hyperreticulated network have been also examined. Equilibrium studies were conducted in 25 mg L -1 initial phenol concentrations, 6.5-9 solution pH and at temperature of 30 deg. C. The experimental data were analyzed by the Langmuir and Freundlich isotherm models. Besides, the cherry stone based activated carbons were carried out by using zinc chloride and KOH activation agents at different chemical ratios (activating agent/precursor), to develop carbons with well-developed porosity. The cherry stone activated carbon prepared using KOH as a chemical agent showed a high surface area. According to the results, activated carbons had excellent adsorptive characteristics in comparison with polymeric sorbents and commercial activated carbon for the phenol removal from the aqueous solutions.

  16. Influence of adrenaline on the activity of succinate dehydrogenase in peripheral blood lymphocytes of irradiated rats

    International Nuclear Information System (INIS)

    Koroleva, L.V.; Vasin, M.V.

    1988-01-01

    In experiments with albino mongrel female rats, the influence of adrenaline on succinate dehydrogenase (SDG) activity in the peripheral blood lymphocytes of irradiated and intact animals has been investigated. Two minutes after the intraperitoneal administration of adrenaline (1 mg/kg) to intact rats SDG activity sharply rises and 3-4 min it drastically falls. In 6 to 8 min the second peak in the enzyme activity is registered. Twenty minutes after irradiation of rats in the crano-caudal direction with a dose of 75 Gy delivered to head, the reaction to adrenaline, manifested by the rise in SDG activity, is absent

  17. Crystallization and X-ray diffraction analysis of SpaE, a basal pilus protein from the gut-adapted Lactobacillus rhamnosus GG.

    Science.gov (United States)

    Mishra, Arjun K; Megta, Abhin Kumar; Palva, Airi; von Ossowski, Ingemar; Krishnan, Vengadesan

    2017-06-01

    SpaE is the predicted basal pilin subunit in the sortase-dependent SpaFED pilus from the gut-adapted and commensal Lactobacillus rhamnosus GG. Thus far, structural characterization of the cell-wall-anchoring basal pilins has remained difficult and has been limited to only a few examples from pathogenic genera and species. To gain a further structural understanding of the molecular mechanisms that are involved in the anchoring and assembly of sortase-dependent pili in less harmful bacteria, L. rhamnosus GG SpaE for crystallization was produced by recombinant expression in Escherichia coli. Although several attempts to crystallize the SpaE protein were unsuccessful, trigonal crystals that diffracted to a resolution of 3.1 Å were eventually produced using PEG 3350 as a precipitant and high protein concentrations. Further optimization with a combination of additives led to the generation of SpaE crystals in an orthorhombic form that diffracted to a higher resolution of 1.5 Å. To expedite structure determination by SAD phasing, selenium-substituted (orthorhombic) SpaE crystals were grown and X-ray diffraction data were collected to 1.8 Å resolution.

  18. The effects of balance and postural stability exercises on spa based rehabilitation programme in patients with ankylosing spondylitis.

    Science.gov (United States)

    Gunay, Selim M; Keser, Ilke; Bicer, Zemzem T

    2018-01-01

    Ankylosing spondylitis (AS) can cause severe functional disorders that lead to loss of balance. The aim of this study was to investigate the effects of balance and postural stability exercises on spa based rehabilitation programme in AS subjects. Twenty-one participants were randomized to the study (n= 11) and control groups (n= 10). Patients balance and stability were assessed with the Berg Balance Scale (BBS), Timed Up and Go (TUG) Test, Single Leg Stance Test (SLST) and Functional Reach Test (FRT). AS spesicied measures were used for assessing to other parameters. The treatment plan for both groups consisted of conventional transcutaneous electrical nerve stimulation (TENS), spa and land-based exercises 5 days per week for 3 weeks. The study group performed exercises based on postural stability and balance with routine physiotherapy practice in thermal water and in exercise room. The TUG, SLST and FUT scores were significantly increased in the study group. In both groups, the BASMI, BASFI, BASDAI and ASQoL scores decreased significantly by the end of the treatment period (pbalance and stability exercises in addition to spa based routine approaches can increase the duration of maintaining balance and can improve the benefits of physiotherapy.

  19. spa Typing and Multilocus Sequence Typing Show Comparable Performance in a Macroepidemiologic Study of Staphylococcus aureus in the United States.

    Science.gov (United States)

    O'Hara, F Patrick; Suaya, Jose A; Ray, G Thomas; Baxter, Roger; Brown, Megan L; Mera, Robertino M; Close, Nicole M; Thomas, Elizabeth; Amrine-Madsen, Heather

    2016-01-01

    A number of molecular typing methods have been developed for characterization of Staphylococcus aureus isolates. The utility of these systems depends on the nature of the investigation for which they are used. We compared two commonly used methods of molecular typing, multilocus sequence typing (MLST) (and its clustering algorithm, Based Upon Related Sequence Type [BURST]) with the staphylococcal protein A (spa) typing (and its clustering algorithm, Based Upon Repeat Pattern [BURP]), to assess the utility of these methods for macroepidemiology and evolutionary studies of S. aureus in the United States. We typed a total of 366 clinical isolates of S. aureus by these methods and evaluated indices of diversity and concordance values. Our results show that, when combined with the BURP clustering algorithm to delineate clonal lineages, spa typing produces results that are highly comparable with those produced by MLST/BURST. Therefore, spa typing is appropriate for use in macroepidemiology and evolutionary studies and, given its lower implementation cost, this method appears to be more efficient. The findings are robust and are consistent across different settings, patient ages, and specimen sources. Our results also support a model in which the methicillin-resistant S. aureus (MRSA) population in the United States comprises two major lineages (USA300 and USA100), which each consist of closely related variants.

  20. Expression, purification, crystallization and preliminary crystallographic analysis of SpaA, a major pilin from Corynebacterium diphtheriae

    International Nuclear Information System (INIS)

    Kang, Hae Joo; Paterson, Neil G.; Baker, Edward N.

    2009-01-01

    SpaA, one of the major pilins of C. diphtheriae, has been expressed, purified and crystallized and X-ray diffraction data have been collected to 1.6 Å resolution. Bacterial pili are cell-surface organelles that are critically involved in adhesion to host cells, leading to the colonization of host tissues and the establishment of infections. Whereas the pili of Gram-negative bacteria have been extensively studied, those of Gram-positive bacteria came to light only recently after the discovery and characterization of Corynebacterium diphtheriae pili. These newly discovered pili are formed by the covalent polymerization of pilin subunits catalyzed by sortase enzymes, making them fundamentally different from the noncovalent pilin assemblies of Gram-negative bacteria. Here, the expression, crystallization and preliminary crystallographic analysis of SpaA, which forms the shaft of one of the three types of pili expressed by C. diphtheriae, are reported. SpaA 53–486 crystals diffracted to 1.6 Å resolution and belonged to space group P2 1 2 1 2 1 , with unit-cell parameters a = 34.9, b = 64.1, c = 198.7 Å, α = β = γ = 90°

  1. Giving children a voice: Exploring qualitative perspectives on factors influencing recess physical activity

    DEFF Research Database (Denmark)

    Pawlowski, Charlotte Skau; Schipperijn, Jasper; Tjørnhøj-Thomsen, Tine

    2018-01-01

    Facilitators and barriers to recess physical activity are not well understood. To date, research on recess physical activity has predominantly focused on quantitative measures typically focusing on a narrow set of predefined factors, often constructed by adults. To really understand the factors...... 11–12-year-old children. The socio-ecological model was used as the overall theoretical framework. Twelve factors were identified as influencing the children’s recess physical activity: bodily self-esteem and ability; gender; gendered school culture; peer influence; conflicts and exclusion; space...... and place experiences; lack of play facilities; outdoor play policy; use of electronic devices; recess duration; organised activities; and weather. These factors were located within different layers of the socio-ecological model, but were interdependent. The findings speak for implementing a combination...

  2. Analysing the influence of human activity on runoff in the Weihe River basin

    Directory of Open Access Journals (Sweden)

    C. Shen

    2015-05-01

    Full Text Available Changing runoff patterns can have profound effects on the economic development of river basins. To assess the impact of human activity on runoff in the Weihe River basin, principal component analysis (PCA was applied to a set of 17 widely used indicators of economic development to construct general combined indicators reflecting different types of human activity. Grey relational analysis suggested that the combined indicator associated with agricultural activity was most likely to have influenced the changes in runoff observed within the river basin during 1994–2011. Curve fitting was then performed to characterize the relationship between the general agricultural indicator and the measured runoff, revealing a reasonably high correlation (R2 = 0.393 and an exponential relationship. Finally, a sensitivity analysis was performed to assess the influence of the 17 individual indicators on the measured runoff, confirming that indicators associated with agricultural activity had profound effects whereas those associated with urbanization had relatively little impact.

  3. Development of scales to assess children's perceptions of friend and parental influences on physical activity

    Directory of Open Access Journals (Sweden)

    Brockman Rowan

    2009-10-01

    Full Text Available Abstract Background Many children do not meet physical activity guidelines. Parents and friends are likely to influence children's physical activity but there is a shortage of measures that are able to capture these influences. Methods A new questionnaire with the following three scales was developed: 1 Parental influence on physical activity; 2 Motives for activity with friends scale; and 3 Physical activity and sedentary group normative values. Content for each scale was informed by qualitative work. One hundred and seventy three, 10-11 year old children completed the new questionnaire twice, one week apart. Participants also wore an accelerometer for 5 days and mean minutes of moderate to vigorous physical activity, light physical activity and sedentary time per day were obtained. Test-retest reliability of the items was calculated and Principal Component analysis of the scales performed and sub-scales produced. Alphas were calculated for main scales and sub-scales. Correlations were calculated among sub-scales. Correlations between each sub-scale and accelerometer physical activity variables were calculated for all participants and stratified by sex. Results The Parental influence scale yielded four factors which accounted for 67.5% of the variance in the items and had good (α > 0.7 internal consistency. The Motives for physical activity scale yielded four factors that accounted for 66.1% and had good internal consistency. The Physical activity norms scale yielded 4 factors that accounted for 67.4% of the variance, with good internal consistency for the sub-scales and alpha of .642 for the overall scale. Associations between the sub-scales and physical activity differed by sex. Although only 6 of the 11 sub-scales were significantly correlated with physical activity there were a number of associations that were positively correlated >0.15 indicating that these factors may contribute to the explanation of children's physical activity

  4. Cellular uptake and processing of surfactant lipids and apoprotein SP-A by rat lung

    International Nuclear Information System (INIS)

    Young, S.L.; Wright, J.R.; Clements, J.A.

    1989-01-01

    The intracellular pathways and the kinetics of metabolism of surfactant apoprotein and lipid, which may be recycled from the alveolar space, are largely unknown. We used a lipid-apoprotein complex made from liposomes of pure lipids in a ratio found in mammalian pulmonary surfactant plus surfactant apoprotein (SP-A, Mr = 26,000-36,000) to test some possible relationships in the recycling of these major surfactant components between intrapulmonary compartments. After intratracheal instillation of 80 microliters of an apoprotein-liposome mixture with separate radiolabels in the lipid and the apoprotein, rats were killed at times from 8 min to 4 h later. The lungs were lavaged with saline, and subcellular fractions were isolated on discontinuous sucrose density gradients. Both the [ 14 C]lipid radiolabel and the 125 I-apoprotein radiolabel demonstrated a time-dependent increase in radioactivity recovered in a lamellar body-enriched fraction. Uptake of the radiolabels into other subcellular fractions did not exhibit a clear-cut time dependence; more of the protein than the lipid radiolabel was found in the Golgi-rich and microsomal fractions. We conclude that both the lipid and apoprotein portions of lung surfactant are taken up by lung cells and are incorporated into secretory granules of the cells

  5. Balneotherapy for chronic plaque psoriasis at Comano spa in Trentino, Italy.

    Science.gov (United States)

    Peroni, Anna; Gisondi, Paolo; Zanoni, Mauro; Girolomoni, Giampiero

    2008-07-01

    Thermal therapy is used worldwide in the treatment of psoriasis but few controlled studies have evaluated its efficacy and safety. We studied the efficacy and safety of balneotherapy compared to photobalneotherapy performed at Comano spa in Trentino, Italy, in chronic plaque psoriasis in a prospective, nonrandomized, open study. Three hundred adult patients with mild to severe chronic plaque psoriasis were assigned to either balneotherapy or photobalneotherapy with daily narrow-band ultraviolet B for a mean period of 1 or 2 weeks, reflecting the times that most patients can dedicate to thermal therapy. Patients were evaluated at baseline and end of treatment for psoriasis area and severity index (PASI) and body surface area; self-administered PASI (SAPASI) and Skindex-29 were evaluated at the same times, and also at 4 months by a mailed questionnaire. One-week balneotherapy or photobalneotherapy resulted in a significant reduction in PASI score (11.54% +/- 2.76 and 12.76% +/- 3.79, respectively; mean +/- standard deviation; p balneotherapy alone, with PASI reduction of 19.8% +/- 24.5 and 13.5% +/- 23.1 (p balneotherapy and photobalneotherapy could thus be offered to patients willing to temporarily discontinue pharmacologic therapy or as adjuvant therapy.

  6. Stable isotopic and mineralogical studies of hydrothermal alteration at Arima Spa, Southwest Japan

    International Nuclear Information System (INIS)

    Masuda, Harue; Osaka City Univ.; Sakai, Hitoshi; Chiba, Hitoshi; Matsuhisa, Yukihiro; Nakamura, Takeshi

    1986-01-01

    The waters of Arima Spa, Southwest Japan, have high salinity (Cl = 54 g/kg) and high isotopic ratios (deltaD = -32, and delta 18 O = +10 per mille), and issue from shallow wells drilled into altered rhyolitic pyroclastic rocks of Cretaceous age. Alteration of the host rocks occurred in two stages. The earlier regional alteration stage is characterized by the presence of 2M- and 1M-type muscovite, albite, chlorite, calcite and epidote, whereas muscovite and Fe-chlorite formation at the expense of partly albitized plagioclase and altered biotite or hornblende occurred in the following hydrothermal stage. Pyrite, sphalerite, galena and siderite are present in the central part of the hydrothermal alteration zone. Oxygen and hydrogen isotopic ratios of secondary muscovite show that regional alteration proceeded under the meteoric circulation, and that the hydrothermal fluid for the second stage had chemical and stable isotopic characteristics of non-meteoric origin similar to the present-day Arima brine. The oxygen and to a lesser extent the hydrogen isotopic ratios of the muscovite rapidly decrease with increasing distance from the central zone of hydrothermal alteration. The isotopic variation is best interpreted as reflecting rapidly decreasing fluid/rock ratios with increasing distance of fluid penetration from the narrow hydrothermal alteration zone into the surrounding area. The results are discussed. (author)

  7. Characteristics of thermal-mineral waters in Backa region (Vojvodina) and their exploitation in spa tourism

    Energy Technology Data Exchange (ETDEWEB)

    Kosic, Kristina; Pivac, Tatjana; Romelic, Jovan; Lazic, Lazar; Stojanovic, Vladimir [Faculty of Science, Department of Geography, Tourism and Hotel Management, University of Novi Sad, Trg Dositeja Obradovica 3, 21000 Novi Sad (RS)

    2011-01-15

    Hydropower, biomass, biogas, biofuels, wind power, solar energy and geothermal energy are the major resources to provide Backa region with most of its. Backa extends between 45 16' and 46 22' of the northern latitude and 18 36' and 20 37' of the eastern longitude. It occupies the north-eastern part of Vojvodina, i.e. the most north-western part of the Republic of Serbia. That is historical-geographic territory bordered on the Danube on its western and eastern side, the Tisa on its eastern side and with the state border towards Hungary on the north. In this paper, the focus will be on renewable sources, specifically geothermal energy in Backa region. The paper analyzes the characteristics of thermal-mineral waters in Backa, the condition and possibilities of their exploitation in spa tourism, and in other economic branches. The tradition of thermo-mineral waters exploitation in spas and public baths is rather long. Today, this type of thermo-mineral waters exploitation in Backa is the widest spread. Permanent, i.e. continuous exploiters of thermal-mineral waters in Backa are primarily balneal-rehabilitation centres and exploiters using the water for technological purposes. (author)

  8. Hydrogeothermal resources in spa areas of Serbia: Main properties and possible improvement of use

    Directory of Open Access Journals (Sweden)

    Dokmanović Petar B.

    2012-01-01

    Full Text Available Geological complexity of the territory of Serbia is a world curiosity: six main geo-tectonic regions and tens sub-regions are delineated in a small area of 88,000 km2. Geologic origin and regional structure of some areas has long been the subject of discussion. Notable magmatism and associated tectonic events in the Earth's crust provided for a fairly large hydrogeothermal resource potential, which is manifested in more than 250 warm (mainly mineral springs and more than 100 hydrothermal wells. Thermal springs and wells together discharge some 5 m3/s. This potential is used in part for balneal therapy (waters differ in temperature and chemical composition in the spa areas of Serbia. The amounts of thermal water unused therapeutically or the amounts of heat energy from unused geo-thermal water may be used in almost all spas for space heating/cooling and thus increase the efficiency of the thermal water energy utilization. This also will be cost-effective, reduce emission of noxious gases, and improve the environmental-health image of the resorts. The hydrogeothermal resources are described for 29 spas with 700 l/s total discharge capacity of water temperature between 25°C and 96ºC, or an overall heat energy of 78.40 MWt. Feasibility of additional energy utilization of thermal water in spas is generally considered.

  9. Influence of amendments on soil arsenic fractionation and phytoavailability by Pteris vittata L.

    Science.gov (United States)

    Yan, Xiulan; Zhang, Min; Liao, Xiaoyong; Tu, Shuxin

    2012-06-01

    Increasing availability of soil arsenic is of significance for accelerating phytoremediation efficiency of As-polluted sites. The effects of seven amendments, i.e., citrate, oxalate, EDTA, sodium polyacrylate (SPA), phosphate rock (PR), single superphosphate (SSP), and compost on fractionation and phytoavailability of soil As were investigated in lab culture experiment. The results showed that the addition of PR, SPA, EDTA or compost to soils significantly increased the concentration of NaHCO(3)-extractable As over a 120 d incubation period compared with the control (amendment-free) soil. Then, the four amendments were selected to add to As-contaminated soil growing Pteris vittata. It was concluded that As accumulation by the fern increased significantly under the treatments of PR and SPA by 25% and 31%, respectively. For As fractionation in soil, SPA increased Fe-As significantly by 51% and PR increased Ca-As significantly by 18%, while both the two amendments reduced occluded-As by 16% and 19%, respectively. Adding PR and SPA in soil increased the activities of urease and neutral phosphatase resulting from the improvement the fertility and physical structure of the soil, which benefits plant growth and As absorption of P. vittata. The results of the research revealed that both PR and SPA were effective amendments for improving phytoremediation of As-contaminated sites by P. vittata. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Post-Materialism as a Cultural Factor Influencing Entrepreneurial Activity across Nations

    OpenAIRE

    Uhlaner, L.M.; Thurik, A.R.; Hutjes, J.

    2002-01-01

    textabstractThe study of the determinants of entrepreneurship at the country level has been dominated by economic influences. The relative stability of differences in levels of entrepreneurship across coun-tries suggests that other forces such as certain institutional and/or cultural factors are at play. The objective of this paper is to explore how post-materialism explains differences in entrepreneurial activity across countries. Entrepreneurial activity is defined as the percent of a count...

  11. Influence of cure activator on the structure and properties of rubbers

    Directory of Open Access Journals (Sweden)

    O. V. Karmanova

    2013-01-01

    Full Text Available The influence of vulcanization activator type on the properties of the compositions and elastic-strength characteristics of rubber was studied. Found that the modification of zinc oxide as the basis of actual formation curing vulcanization agents leads to an increase of vulcanization active centers, providing an increase in the velocity of rubber vulcanization and improvement of physical and mechanical rubber’s properties.

  12. ACTIVITY OF LICHENS UNDER THE INFLUENCE OF SNOW AND ICE (18th Symposium on Polar Biology)

    OpenAIRE

    Ludger, KAPPEN; Burkhard, SCHROETER

    1997-01-01

    A major aim of our investigations is to explain the adaptation of vegetation to the peculiar environmental conditions in polar regions. Our concept describes the main limiting and favorable factors influencing photosynthetic production of cryptogams, mainly lichens. Snow and ice-usually stress factors to the activity of plants-can be effectively used by lichens because of their poikilohydrous nature. Light, the basic driving force for photosynthetic activity, may be deleterious under certain ...

  13. Engaging luxury consumers in social media : Does active consumer engagement influence brand image?

    OpenAIRE

    Åvall, Martina

    2017-01-01

    This study aimed to investigate the effects of active consumer engagement within social media based brand communities on the brand image and luxury consumers’ desire to pur-chase luxury goods. The purpose of this study was to prove that by actively engaging con-sumers on social media luxury brands can positively influence the way consumers perceive the brand and through it increase consumers’ intention to purchase their products and services. Secondary research was carried out through col...

  14. Influence of a 12.8-km military load carriage activity on lower limb gait mechanics and muscle activity.

    Science.gov (United States)

    Rice, Hannah; Fallowfield, Joanne; Allsopp, Adrian; Dixon, Sharon

    2017-05-01

    The high stress fracture occurrence in military populations has been associated with frequent load carriage activities. This study aimed to assess the influence of load carriage and of completing a load carriage training activity on gait characteristics. Thirty-two Royal Marine recruits completed a 12.8-km load carriage activity as part of their military training. Data were collected during walking in military boots, pre and post-activity, with and without the additional load (35.5 kg). Ground contact time, lower limb sagittal plane kinematics and kinetics, and electromyographic variables were obtained for each condition. When carrying load, there was increased ground contact time, increased joint flexion and joint moments, and increased plantar flexor and knee extensor muscle activity. Post-activity, there were no changes to kinematic variables, knee extensor moments were reduced, and there was evidence of plantar flexor muscle fatigue. The observed gait changes may be associated with stress fracture development. Practitioner Summary: This study identified gait changes due to load carriage and after a military load carriage training activity. Such activities are associated with lower limb stress fractures. A pre-post study design was used. Gait mechanics changed to a greater extent when carrying load, than after completion of the activity when assessed without load.

  15. The influence of alcohol consumption on sickness presenteeism and impaired daily activities. The WIRUS screening study.

    Science.gov (United States)

    Aas, Randi Wågø; Haveraaen, Lise; Sagvaag, Hildegunn; Thørrisen, Mikkel Magnus

    2017-01-01

    Alcohol use is a global health issue and may influence activity performance in a variety of domains, including the occupational and domestic spheres. The aim of the study was to examine the influence of annual drinking frequency and binge drinking (≥6 units at one occasion) on activity impairments both at work (sickness presenteeism) and outside the workplace. Employees (n = 3278), recruited from 14 Norwegian private and public companies, responded to a questionnaire containing questions from the Alcohol Use Disorders Identification Test (AUDIT) and the Workplace Productivity and Activity Impairment questionnaire (WPAI). Multiple hierarchical regression analyses revealed that binge drinking was associated with both sickness presenteeism and impaired daily activities, even after controlling for gender, age, educational level, living status and employment sector. Annual drinking frequency was associated with impaired daily activities, but not sickness presenteeism. Binge drinking seems to have a stronger influence on activity performance both at work and outside the workplace than drinking frequency. Interventions targeting alcohol consumption should benefit from focusing on binge drinking behavior.

  16. The influence of alcohol consumption on sickness presenteeism and impaired daily activities. The WIRUS screening study.

    Directory of Open Access Journals (Sweden)

    Randi Wågø Aas

    Full Text Available Alcohol use is a global health issue and may influence activity performance in a variety of domains, including the occupational and domestic spheres. The aim of the study was to examine the influence of annual drinking frequency and binge drinking (≥6 units at one occasion on activity impairments both at work (sickness presenteeism and outside the workplace.Employees (n = 3278, recruited from 14 Norwegian private and public companies, responded to a questionnaire containing questions from the Alcohol Use Disorders Identification Test (AUDIT and the Workplace Productivity and Activity Impairment questionnaire (WPAI.Multiple hierarchical regression analyses revealed that binge drinking was associated with both sickness presenteeism and impaired daily activities, even after controlling for gender, age, educational level, living status and employment sector. Annual drinking frequency was associated with impaired daily activities, but not sickness presenteeism.Binge drinking seems to have a stronger influence on activity performance both at work and outside the workplace than drinking frequency. Interventions targeting alcohol consumption should benefit from focusing on binge drinking behavior.

  17. Momentary assessment of contextual influences on affective response during physical activity.

    Science.gov (United States)

    Dunton, Genevieve Fridlund; Liao, Yue; Intille, Stephen; Huh, Jimi; Leventhal, Adam

    2015-12-01

    Higher positive and lower negative affective response during physical activity may reinforce motivation to engage in future activity. However, affective response during physical activity is typically examined under controlled laboratory conditions. This research used ecological momentary assessment (EMA) to examine social and physical contextual influences on momentary affective response during physical activity in naturalistic settings. Participants included 116 adults (mean age = 40.3 years, 73% female) who completed 8 randomly prompted EMA surveys per day for 4 days across 3 semiannual waves. EMA surveys measured current activity level, social context, and physical context. Participants also rated their current positive and negative affect. Multilevel models assessed whether momentary physical activity level moderated differences in affective response across contexts controlling for day of the week, time of day, and activity intensity (measured by accelerometer). The Activity Level × Alone interaction was significant for predicting positive affect (β = -0.302, SE = 0.133, p = .024). Greater positive affect during physical activity was reported when with other people (vs. alone). The Activity Level × Outdoors interaction was significant for predicting negative affect (β = -0.206, SE = 0.097, p = .034). Lower negative affect during physical activity was reported outdoors (vs. indoors). Being with other people may enhance positive affective response during physical activity, and being outdoors may dampen negative affective response during physical activity. (c) 2015 APA, all rights reserved).

  18. School Administrators' Perceptions of Factors that Influence Children's Active Travel to School

    Science.gov (United States)

    Price, Anna E.; Pluto, Delores M.; Ogoussan, Olga; Banda, Jorge A.

    2011-01-01

    Background: Increasing children's active travel to school may be 1 strategy for addressing the growing prevalence of obesity among school age children. Using the School Travel Survey, we examined South Carolina school district leaders' perceptions of factors that influence elementary and middle school students walking to school. Methods: Frequency…

  19. N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme Activity Implications for Hyperglycemia

    NARCIS (Netherlands)

    Riedl, Eva; Koeppel, Hannes; Pfister, Frederick; Peters, Verena; Sauerhoefer, Sibylle; Sternik, Paula; Brinkkoetter, Paul; Zentgraf, Hanswalter; Navis, Gerjan; Henning, Robert H.; Van Den Born, Jacob; Bakker, Stephan J. L.; Janssen, Bart; van der Woude, Fokko J.; Yard, Benito A.

    OBJECTIVE-The (CTG)(n) polymorphism in the serum carnosinase (CN-1) gene affects CN-1 secretion Since CN-1 is heavily glycosylated and glycosylation might influence protein secretion as well, we tested the role of N-glycosylation for CN-1 secretion and enzyme activity. We also tested whether CN-1

  20. Implementing an Active Learning Environment to Influence Students' Motivation in Biochemistry

    Science.gov (United States)

    Cicuto, Camila Aparecida Tolentino; Torres, Bayardo Baptista

    2016-01-01

    The Biochemistry: Biomolecules Structure and Metabolism course's goal is to promote meaningful learning through an active learning environment. Thus, study periods (SP) and discussion groups (DG) are used as a substitute for lecture classes. The goal of this study was to evaluate how this learning environment influences students' motivation (n =…

  1. Influence of layer eccentricity on the resonant properties of cylindrical active coated nano-particles

    DEFF Research Database (Denmark)

    Thorsen, R. O.; Arslanagic, Samel

    2015-01-01

    We report on the influence of the layer eccentricity on the resonant properties of active coated nano-particles made of a silver core and gain impregnated silica shell illuminated by a near-by magnetic line source. For a fixed over-all size of the particle, designs with small and large cores...

  2. Does Weight Status Influence Associations between Children's Fundamental Movement Skills and Physical Activity?

    Science.gov (United States)

    Hume, Clare; Okely, Anthony; Bagley, Sarah; Telford, Amanda; Booth, Michael; Crawford, David; Salmon, Jo

    2008-01-01

    This study sought to determine whether weight status influences the association among children's fundamental movement skills (FMS) and physical activity (PA). Two hundred forty-eight children ages 9-12 years participated. Proficiency in three object-control skills and two locomotor skills was examined. Accelerometers objectively assessed physical…

  3. The Influence of Body Discourses on Adolescents' (Non)Participation in Physical Activity

    Science.gov (United States)

    Beltrán-Carrillo, Vicente J.; Devís-Devís, José; Peiró-Velert, Carmen

    2018-01-01

    Drawing on semi-structured interviews with older adolescents, this article examines how healthism, ideal body discourses and performative body discourses influence their (non)participation in physical activity (PA) and their identity construction concerning exercise, sport and physical education. We illustrate that body transformation through PA,…

  4. How design-inclusive UXR influenced the integration of project activities. Three design cases from industry

    NARCIS (Netherlands)

    van Kollenburg, J.W.M.; Bogers, S.J.A.; Deckers, E.J.L.; Frens, J.W.; Hummels, C.C.M.

    2017-01-01

    In this paper, we discuss how the implementation of design-inclusive User Experience Research (UXR) has influenced the composition of UXR and design activities in the industrial setting of Philips Design. We present three design case studies that were executed in a time span of three years: a baby

  5. Factors influencing the determination of fluorite by means of neutron activation analysis

    International Nuclear Information System (INIS)

    Lutze, H.

    1975-01-01

    Proceeding from the necessity of a rapid analysis of fluorite by neutron activation of an unprepared drill core the influence of interfering elements, of inhomogeneous fluorite distribution, of the sample volume and of moisture are examined. Recommendations are given to overcome these interferences. (author)

  6. Outsourcing Extra-Curricular Activities: A Management Strategy in a Time of Neoliberal Influence

    Science.gov (United States)

    Ng, Shun Wing; Chan, Tsan Ming Kenneth; Yuen, Wai Kwan Gail

    2017-01-01

    Purpose: The purpose of this paper is to report on an exploratory study designed to illuminate the complexity of outsourcing extra-curricular activities (ECAs) in primary schools in a time of neoliberal influence and to examine the views of teaching professionals on the reasons, issues and considerations of outsourcing ECAs such as the dynamic…

  7. Influences of Technology-Related Playful Activity and Thought on Moral Development

    Science.gov (United States)

    Bergen, Doris; Davis, Darrel

    2011-01-01

    Many early developmental theorists such as Freud, Erikson, Piaget, and Vygotsky suggested that play--which the authors of this article define as both playful activity and playful thought--had the power to influence the moral emotions, behaviors, and reasoning of children. More recent researchers have also found evidence of moral development in…

  8. ANALYSIS OF THE EXTERNAL FACTORS OF INFLUENCE ON INNOVATION ACTIVITY OF AN INDUSTRIAL ENTERPRISE

    Directory of Open Access Journals (Sweden)

    I. A. Salikov

    2014-01-01

    Full Text Available Summary. For successful functioning and development of the enterprise is a need to strive as possible deeper and more dynamic influence on parameters and objects OK-environmental management, primarily due to increase their innovation activity. Innovative activity of enterprises influenced by many factors. They can be classified on the factors of direct influence (micro and factors of indirect impacts (macro. Factors of direct impact of the influence on the pace and scale of development of the enterprise, on its effectiveness, because the whole spectrum of these factors acts as a limiter. Macro factors create the General conditions of existence of the enterprise in the external environment. To analyses these factors approach was used to SNW-analysis. As a result of analysis, factors of micro and macro-were classified on: stimulating, it minesweepers and dissuasive. Also studied were the degree of influence of these factors on the innovative activity of the enterprise. Reviewed rating factors hindering the development of innovation activity of industrial enterprise in Russia. In the result of which identified factors that hinder the development of innovative activity, and justified in the direction of overcoming them. It should be noted that the distinction between enabling and constraining factors is rather thin and conditional. So, the factors initially restraining innovation, at a certain point can be transformed into a stimulus for its development. Accounting for these factors, creation of necessary conditions and introduction of innovations in various aspects of the functioning of industrial enterprises will allow them to provide competitor-term benefits and sustainable development in a rapidly changing environment and the external environment.

  9. Parental Activity as Influence on Childrenˋs BMI Percentiles and Physical Activity

    Directory of Open Access Journals (Sweden)

    Nanette Erkelenz, Susanne Kobel, Sarah Kettner, Clemens Drenowatz, Jürgen M. Steinacker and the Research Group "Join the Healthy Boat - Primary School"

    2014-09-01

    Full Text Available Parents play a crucial role in the development of their children’s lifestyle and health behaviour. This study aims to examine associations between parental physical activity (PA and children’s BMI percentiles (BMIPCT, moderate to vigorous PA (MVPA as well as participation in organised sports. Height and body weight was measured in 1615 in German children (7.1 ± 0.6 years, 50.3% male and converted to BMIPCT. Parental BMI was calculated based on self-reported height and body weight. Children’s MVPA and sports participation as well as parental PA were assessed via parental questionnaire. Analysis of covariance (ANCOVA, controlling for age and family income was used to examine the association between parental and children’s PA levels as well as BMIPCT. 39.7% of the parents classified themselves as physically active and 8.3% of children were classified as overweight or obese. Lower BMIPCT were observed with both parents being physically active (44.5 ± 26.3 vs. 50.2 ± 26.9 and 52.0 ± 28.4, respectively. There was no association between parental and children’s PA levels but children with at least one active parent displayed a higher participation in organised sports (102.0 ± 96.6 and 117.7 ± 123.6 vs. 73.7 ± 100.0, respectively. Children of active parents were less likely to be overweight and obese. The lack of association between subjectively assessed parental PA and child MVPA suggests that parental support for PA in children is more important than parents being a role model. More active parents, however, may be more likely to facilitate participation in organised sports. These results underline the importance of the inclusion of parents in health promotion and obesity prevention programmes in children.

  10. Activities pattern of planned settlement’s residence and its influence toward settlement design

    Science.gov (United States)

    Nirfalini Aulia, Dwira

    2018-03-01

    Everyday activity of residents in a housing area will create activities pattern. Utilization of public spaces in a housing area with repeating activities pattern will affect the design of public spaces. Changes in public space usage in a housing area happen as a result of residents’ activities pattern. The goal of this paper is to identify residents’ activity pattern and connect its influence towards public spaces utilization in planned housing in micro and urban area in macro. Housing residents classified into four respondent groups based on marriage status which is unmarried, single parents, the family without child and family with a child. The method used in this research is the qualitative descriptive approach. Research finding showed that housing area with housing facilities capable of creating happiness and convenience for its residents doing their activities in public spaces.

  11. Active-site titration analysis of surface influence on immobilized Candida antarctica Lipase B activity

    Science.gov (United States)

    Matrix morphology and surface polarity effects were investigated for Candida antarctica lipase B immobilization. Measurements of the amount of lipase immobilized (bicinchoninic acid method) and the catalyst’s tributyrin hydrolysis activity, coupled with a determination of the lipase’s functional fr...

  12. Perceived difficulties using everyday technology after acquired brain injury: influence on activity and participation.

    Science.gov (United States)

    Lindén, Anita; Lexell, Jan; Lund, Maria Larsson

    2010-12-01

    Using everyday technology (ET) is a prerequisite for activities and participation at home and in the community. It is well known that persons with an acquired brain injury (ABI) can have limitations in activities of daily living but our knowledge of their difficulties using ET is not known. Thirty-six persons (27 men and 9 women, mean age 44 years, age range 26-60) with an ABI (2-10 years post injury) were interviewed, using the Everyday Technology Use Questionnaire (ETUQ), about their perceived difficulties using ET and how these difficulties influenced their everyday activities and their possibilities to participate at home and in the community. A majority (78%) of the persons reported difficulties using ET. The most common difficulties were related to the use of telecommunication and computers. Despite these difficulties, a majority still used most objects and services independently. Twenty-six participants (72%) perceived that their difficulties using ET influenced their everyday activities and their possibility to participate at home and in the community. The results indicate that rehabilitation following an ABI should consider whether clients' use of ET influences their activity and participation and adopt interventions accordingly. The results also indicate that difficulties using ET need to be considered in the design of community services to prevent societal barriers.

  13. Mechanical activation of ceramic powders and its influence on the quality of the refractory linings

    International Nuclear Information System (INIS)

    Ceganac, Z.; Acimovic, Z.; Andric, Lj.; Petrov, M.; Mihajlovic, S.

    2003-01-01

    In the paper we present results of the investigation of the influence of mechanical activation of ceramic powders-talc and alumina, on the quality of refractory linings for casting applications. It is shown that additional fine grinding of ceramic powders increases the quality of the refractory lining. Grinding and activation of the particles with various granulations contributes to the creation of the homogenous continuous layer of refractory lining on the sand moulds and cores, as well as on the evaporating polystyrene patterns for applications in the Lost foam casting process. Refractory linings obtained within the activation of particles procedure have better adherence to moulds, cores and evaporating patterns. (Original)

  14. Influence of acid phosphatase activity on the saccharification of potato maltodextrins by Aspergillus niger glucoamylase

    Energy Technology Data Exchange (ETDEWEB)

    Zyla, K. (Akademia Rolnicza, Cracow (Poland). Dept. of Biotechnology)

    1990-01-01

    A preparation of Aspergillus niger acid phosphatase, which had the temperature optimum 60deg C, pH optimum 1.8-3.0; good stability at pH 4-5, the ability to hydrolyze glucose-6-phosphate at a high rate, and substantial lack of glucogenic activities, was used simultaneously with a glucoamylase in order to learn its influence on the saccharification of potato maltodextrins. The addition of the acid phosphatase activity in amounts that gave the 50 fold increase, as compared to phosphatase activity which naturally occurs in the gluocoamylase (GA) preparation 'AMG-200', was found to influence on the DE level, mainly at the high substrate concentration (40% d.s.) and low glucoamylase dosage (60-100 GAU/kg d.s.). It may also be possible, when using the acid phosphatase addition, to shorten the saccharification time. (orig.).

  15. Influence of Microtexture on Early Plastic Slip Activity in Ti-6Al-4V Polycrystals

    Science.gov (United States)

    Hémery, Samuel; Dang, Van Truong; Signor, Loïc; Villechaise, Patrick

    2018-06-01

    Microtextured regions are known to influence the fatigue performance of titanium alloys. Previous studies revealed that crack initiation, accounting for most of the fatigue life, is triggered by slip activity. The influence of microtextured regions on the early plastic slip activity was presently investigated by means of an in situ tensile test performed inside a scanning electron microscope on a bimodal Ti-6Al-4V polycrystalline specimen. A slip trace analysis was carried out in several regions with different crystallographic textures to highlight potentially different deformation behaviors. Significant stress heterogeneities were revealed through an early slip activation in microtextured regions with a predominant [0001] orientation. This point was shown to be related to a locally increased resolved shear stress. Consequences on behavior under cyclic loadings are finally discussed.

  16. Physical activity in adolescents: analysis of the social influence of parents and friends.

    Science.gov (United States)

    Cheng, Luanna Alexandra; Mendonça, Gerfeson; Farias Júnior, José Cazuza de

    2014-01-01

    To analyze the association between physical activity and social support from parents and friends on the physical activity level among adolescents. Data from 2,361 adolescents (56.6% females; mean age 16.4; SD = 1.2), from public and private high schools were analyzed. The physical activity level of the adolescents, parents, and friends were measured through a questionnaire. Parents' and friends' support and self-efficacy were measured using two previously tested scales. Data analysis was performed using the structural equation modeling in IBM® SPSS® Amos™ 20.0. Physical activity of friends was directly associated with physical activity level of adolescents. Physical activity of the father was associated with that of their sons, and the physical activity of mother was associated with that of their daughters. An indirect association was identified between the physical activity of parents and friends with physical activity level of the adolescents, mediated by social support. Social support was directly associated with physical activity in adolescents of both genders and indirectly mediated by self-efficacy. Parents and friends have a social influence on adolescents' level of physical activity through the mechanism of behavior modeling or through social support, mediated by self-efficacy. Copyright © 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  17. Physical activity in adolescents: analysis of the social influence of parents and friends

    Directory of Open Access Journals (Sweden)

    Luanna Alexandra Cheng

    2014-01-01

    Full Text Available OBJECTIVE: To analyze the association between physical activity and social support from parents and friends on the physical activity level among adolescents. METHODS: Data from 2,361 adolescents (56.6% females; mean age 16.4; SD = 1.2, from public and private high schools were analyzed. The physical activity level of the adolescents, parents, and friends were measured through a questionnaire. Parents' and friends' support and self-efficacy were measured using two previously tested scales. Data analysis was performed usingthe structural equation modeling in IBM(r SPSS(r AmosTM 20.0. RESULTS: Physical activity of friends was directly associated with physical activity level of adolescents. Physical activity of the father was associated with their sons, and the physical activity of mother was associated with their daughters. An indirect association was identified between the physical activity of parents and friends with physical activity level of the adolescents, mediated by social support. Social support was directly associated with physical activity in adolescents of both genders and indirectly mediated by self-efficacy. CONCLUSIONS: Parents and friends have a social influence on adolescents' level of physical activity through the mechanism of behavior modeling or through social support, mediated by self-efficacy.

  18. Self-Efficacy Manipulation Influences Physical Activity Enjoyment in Chinese Adolescents.

    Science.gov (United States)

    Hu, Liang; Cheng, Shoubin; Lu, Jiaying; Zhu, Lele; Chen, Ling

    2016-02-01

    In this study, we examined the effect of the manipulation of exercise self-efficacy on the enjoyment of physical activity in a sample of 44 Chinese adolescents (age = 14.27 ± .87 y), including 22 boys and 22 girls. The participants were randomized into a low-efficacy or high-efficacy condition, and their self-efficacy beliefs for engaging in moderate-intensity physical activity were manipulated by providing false feedback after a submaximal exercise test. The participants' self-efficacy was measured and compared before and after the exercise test and the participants' enjoyment of physical activity was assessed after the exercise test. It was found that exercise self-efficacy was successfully manipulated in the expected direction in both conditions, which significantly influenced the participants' enjoyment of physical activity. After the exercise test, the participants in the low-efficacy condition reported lower enjoyment scores relative to the high-efficacy participants. These results suggest that self-efficacy may have an important influence on the enjoyment of physical activity among Chinese adolescents. We recommend that physical activity promotion programs should be tailored to enhance adolescents' self-efficacy beliefs and enjoyment of the experience of physical activity.

  19. Influence of External Nitrogen on Nitrogenase Enzyme Activity and Auxin Production in Herbaspirillum seropedicae (Z78).

    Science.gov (United States)

    Yin, Tan Tzy; Pin, Ui Li; Ghazali, Amir Hamzah Ahmad

    2015-04-01

    The production of nitrogenase enzyme and auxins by free living diazotrophs has the potential to influence the growth of host plants. In this study, diazotrophs were grown in the presence of various concentrations of nitogen (N) to determine the optimal concentration of N for microbial growth stimulation, promotion of gaseous N (N2) fixation, and phytohormone production. Therefore, we investigate whether different levels of N supplied to Herbaspirillum seropedicae (Z78) have significant effects on nitrogenase activity and auxin production. The highest nitrogenase activity and the lowest auxin production of H. seropedicae (Z78) were both recorded at 0 gL(-1) of NH4Cl. Higher levels of external N caused a significant decrease in the nitrogenase activity and an increased production of auxins. In a subsequent test, two different inoculum sizes of Z78 (10(6) and 10(12) cfu/ml) were used to study the effect of different percentages of acetylene on nitrogenase activity of the inoculum via the acetylene reduction assay (ARA). The results showed that the optimal amount of acetylene required for nitrogenase enzyme activity was 5% for the 10(6) cfu/ml inoculum, whereas the higher inoculum size (10(12) cfu/ml) required at least 10% of acetylene for optimal nitrogenase activity. These findings provide a clearer understanding of the effects of N levels on diazotrophic nitrogenase activity and auxin production, which are important factors influencing plant growth.

  20. The influence of human physical activity and contaminated clothing type on particle resuspension.

    Science.gov (United States)

    McDonagh, A; Byrne, M A

    2014-01-01

    A study was conducted to experimentally quantify the influence of three variables on the level of resuspension of hazardous aerosol particles from clothing. Variables investigated include physical activity level (two levels, low and high), surface type (four different clothing material types), and time i.e. the rate at which particles resuspend. A mixture of three monodisperse tracer-labelled powders, with median diameters of 3, 5, and 10 microns, was used to "contaminate" the samples, and the resuspended particles were analysed in real-time using an Aerodynamic Particle Sizer (APS), and also by Neutron Activation Analysis (NAA). The overall finding was that physical activity resulted in up to 67% of the contamination deposited on clothing being resuspended back into the air. A detailed examination of the influence of physical activity level on resuspension, from NAA, revealed that the average resuspended fraction (RF) of particles at low physical activity was 28 ± 8%, and at high physical activity was 30 ± 7%, while the APS data revealed a tenfold increase in the cumulative mass of airborne particles during high physical activity in comparison to that during low physical activity. The results also suggest that it is not the contaminated clothing's fibre type which influences particle resuspension, but the material's weave pattern (and hence the material's surface texture). Investigation of the time variation in resuspended particle concentrations indicated that the data were separable into two distinct regimes: the first (occurring within the first 1.5 min) having a high, positive rate of change of airborne particle concentration relative to the second regime. The second regime revealed a slower rate of change of particle concentration and remained relatively unchanged for the remainder of each resuspension event. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Infiltration of the synovial membrane with macrophage subsets and polymorphonuclear cells reflects global disease activity in spondyloarthropathy

    NARCIS (Netherlands)

    Baeten, Dominique; Kruithof, Elli; de Rycke, Leen; Boots, Anemieke M.; Mielants, Herman; Veys, Eric M.; de Keyser, Filip

    2005-01-01

    Considering the relation between synovial inflammation and global disease activity in rheumatoid arthritis (RA) and the distinct but heterogeneous histology of spondyloarthropathy (SpA) synovitis, the present study analyzed whether histopathological features of synovium reflect specific phenotypes

  2. Solar rotation and activity in the past and their possible influence upon the evolution of life

    International Nuclear Information System (INIS)

    Geyer, E.H.

    1981-01-01

    It is proposed that the rotational angular momentum of the lower Main Sequence stars determines the intensity of their magnetic spot activity. As a consequence of this feedback coupling, the stellar rotation and the activity decay exponentially by magnetic braking of the induced stellar flare- and wind-activity. Therefore, the Sun should have rotated much faster and must have shown a very enhanced activity in its early history. This strong solar activity in the past could have influenced the evolution of terrestrial life, and may explain the stagnation of maritime life for about 2 x 10 9 yr, the diversification of species during the Cambrian formation, and the land conquest by life in the upper Silurian system. (Auth.)

  3. Solar rotation and activity in the past and their possible influence upon the evolution of life

    Energy Technology Data Exchange (ETDEWEB)

    Geyer, E H [Bonn Univ. (Germany, F.R.). Sternwarte

    1981-06-01

    It is proposed that the rotational angular momentum of the lower Main Sequence stars determines the intensity of their magnetic spot activity. As a consequence of this feedback coupling, the stellar rotation and the activity decay exponentially by magnetic braking of the induced stellar flare- and wind-activity. Therefore, the Sun should have rotated much faster and must have shown a very enhanced activity in its early history. This strong solar activity in the past could have influenced the evolution of terrestrial life, and may explain the stagnation of maritime life for about 2 x 10/sup 9/ yr, the diversification of species during the Cambrian formation, and the land conquest by life in the upper Silurian system.

  4. Treatment of knee OSTEOARTHRITIS in Spa Health resorts: where do we stand?

    Directory of Open Access Journals (Sweden)

    Salca Amalia

    2015-09-01

    Full Text Available Osteoarthrosis (OA includes degenerative joint disorders that affect articular cartilage in the first instance, followed by changes of all components of the joint. The disease is detected in a proportion of 33% by X-ray in patients aged over 60 years. Knee OA (KOA ranks first among chronic diseases from the point of view of patient disability. This article is a review of guidelines and articles regarding arthrosis, balneotherapy, and balneotherapy in KOA treatment. These were accessed on the Pubmed site in the period March-April 2015. The components of balneo-therapy to which the selected articles refer include mud packs, mineral waters, climate change. These are evaluated in association or in comparison with other methods used in the rehabilitation specialty area for the treatment of KOA: kinesitherapy, intra-articular infiltrations, hydrothermotherapy. The changes induced by these therapies on clinical evolution (pain relief, tenderness, functionality, quality of life, depression symptoms or certain serum parameters (biomarkers of oxidative stress, inflammation and cartilage destruction, vitamin D and other serum metabolites were recorded. The results of our review are consistent with the studies focused on spa modalities in all types of OA. All these data helped defining the role of balneotherapy as part of the rehabilitation program for the treatment of KOA, through the benefits specific to it. Conclusion: Balneotherapy has beneficial effects on patients with KOA, both clinically and serologic improvements. Further studies are needed to quantify these effects using KOA specific markers, to establish a hierarchy of balneotherapy methods based on their effects on KOA, as well as to refine indications depending on the stage of the disease.

  5. Spent fuel performance assessment (SPA) for a hypothetical repository in crystalline formations in Germany

    International Nuclear Information System (INIS)

    Luehrmann, L.; Noseck, U.; Storck, R.

    2000-07-01

    Within the framework of this project a first long-term safety assessment study for a generic German repository with spent nuclear fuel in granite host formations has been performed. Conceptual models have been developed and implemented into the numerical codes. These models describe the relevant processes in the near and far field of the repository. For the nuclide mobilisation and the diffusion-controlled transport through the bentonite barrier the computer code GRAPOS for far-field transport the code CHETMAD has been developed. Transport in the far field has been assumed to take place in a fracture network. As retardation mechanism matrix diffusion accompanied by linear equilibrium sorption on the rock matrix is considered. Both codes have been tested by intercomparison with codes of other countries. The dose rates have been calculated by the code EXCON considering the transport pathways into the biosphere. A reference scenario has been defined. It considers instantaneous saturation of the bentonite immediately after the operational phase of the repository, failure of all containers after 1000 years, diffusion through the bentonite, transport through fractured dykes, which represent a fast transport pathway in the low permeability region of the granite. The nuclide mobilization has been calculated according to a common source term which has been developed by all participants of the SPA project. It is assumed that 25% of the containers are connected to the considered transport pathway in the far field. The nuclides are transported to layers close to the surface. The contaminated water is pumped from a surface well and used for drinking, irrigation, cattle feed and fish ponds. (orig.) [de

  6. The influence of human physical activity and contaminated clothing type on particle resuspension

    International Nuclear Information System (INIS)

    McDonagh, A.; Byrne, M.A.

    2014-01-01

    A study was conducted to experimentally quantify the influence of three variables on the level of resuspension of hazardous aerosol particles from clothing. Variables investigated include physical activity level (two levels, low and high), surface type (four different clothing material types), and time i.e. the rate at which particles resuspend. A mixture of three monodisperse tracer-labelled powders, with median diameters of 3, 5, and 10 microns, was used to “contaminate” the samples, and the resuspended particles were analysed in real-time using an Aerodynamic Particle Sizer (APS), and also by Neutron Activation Analysis (NAA). The overall finding was that physical activity resulted in up to 67% of the contamination deposited on clothing being resuspended back into the air. A detailed examination of the influence of physical activity level on resuspension, from NAA, revealed that the average resuspended fraction (RF) of particles at low physical activity was 28 ± 8%, and at high physical activity was 30 ± 7%, while the APS data revealed a tenfold increase in the cumulative mass of airborne particles during high physical activity in comparison to that during low physical activity. The results also suggest that it is not the contaminated clothing's fibre type which influences particle resuspension, but the material's weave pattern (and hence the material's surface texture). Investigation of the time variation in resuspended particle concentrations indicated that the data were separable into two distinct regimes: the first (occurring within the first 1.5 min) having a high, positive rate of change of airborne particle concentration relative to the second regime. The second regime revealed a slower rate of change of particle concentration and remained relatively unchanged for the remainder of each resuspension event. -- Highlights: • Experimental investigation of the resuspension of hazardous particles from clothing. • Influence of human physical activity

  7. Activity, content, contributors, and influencers of the twitter discussion on urologic oncology.

    Science.gov (United States)

    Borgmann, Hendrik; Loeb, Stacy; Salem, Johannes; Thomas, Christian; Haferkamp, Axel; Murphy, Declan G; Tsaur, Igor

    2016-09-01

    To analyse the activity, content, contributors, and influencers of the Twitter discussion on urologic oncology. We performed a comprehensive quantitative and qualitative Twitter analysis for the hashtags #prostatecancer, #bladdercancer, #kidneycancer, and #testicularcancer. Symplur was used to analyse activity over different time periods and the top influencers of the Twitter discussion. Tweet Archivist and Twitonomy analysis tools were used to assess characteristics of content and contributors. Twitter discussion on urologic oncology in 2014 contained 100,987 tweets created by 39,326 participants. Mean monthly tweet activity was 6,603±2,183 for #prostatecancer, 866±923 for #testicularcancer, 457±477 for #bladdercancer and 401±504 for #kidneycancer. Twitter activity increased by 41% in 2013 and by 122% in 2014. The content analysis detected awareness, cancer, and risk as frequently mentioned words in urologic oncology tweets. Prevalently used related hashtags were the general hashtag #cancer, awareness hashtags, and the respective cancer/urology tag ontology hashtags. Contributors originated from 41 countries on 6 continents and had a mean of 5,864±4,747 followers. They tweeted from platforms on exclusively mobile devices (39%) more frequently than from desktop devices (29%). Health care organizations accounted for 58% of the top influencers in all cancers. The largest proportion of physicians were among the #prostatecancer and #kidneycancer (each 9%) influencers and individual contributors were most frequent in the discussion on #kidneycancer (57%) and #testicularcancer (50%). There is a significant and growing activity in the Twitter discussion on urologic oncology, particularly on #prostatecancer. The Twitter discussion is global, social, and mobile, and merits attention of stakeholders in health care as a promising communication tool. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Influence of healthcare institution managers' proactive approach to communication activities on patient satisfaction

    Directory of Open Access Journals (Sweden)

    Filipović Vinka

    2010-01-01

    Full Text Available Background/Aim. Over the recent years customer satisfaction program as a tool for patient satisfaction has been recognized as an important issue in healthcare services. The aim of this preliminary study was to explore an influence of healthcare institution managers' approach and attitudes to marketing and public relations activities (communication activities, in the context of implementation of customer satisfaction programs, on patient satisfaction. Methods. The study was conducted among managers from different state-owned healthcare institutions (healthcare centers, clinics, hospitals in Serbia. The structured questionnaire form, comprising both open and closed questions, was used as a main research tool. The total number of sent questionnaires was 120; 56 questionnaires were sent back, while 49 of them were valid. Results. It was shown that 42.9% of healthcare institutions apply proactive media approach, and that 35.7% of the organizations have a person who, besides his/her basic engagements, performs activities connected with marketing and public relations. Using Chi-square likelihood ratio test it is confirmed that these activities have a significant role in supporting customer satisfaction program implementation (p < 0.05. The results showed that in 69.4% cases, positive attitude of healthcare institutions managers toward marketing and public relations activities had positive influence on patient satisfaction (p < 0.05. Conclusion. Managers in healthcare sector in Serbia who used proactive approach toward media and who had already institutionalized communication activities with external stakeholders have a positive attitude to implementation of customer satisfaction program. Furthermore, managers' attitude toward communication activities has influence on patient satisfaction.

  9. Influence of early pH decline on calpain activity in porcine muscle

    DEFF Research Database (Denmark)

    Pomponio, Luigi; Ertbjerg, Per; Karlsson, Anders H

    2010-01-01

    myofibril fragmentation at 24 h post-mortem was observed, which was no longer evident in the later phase of the tenderization process. In conclusion, the rate of early pH decline influenced l-calpain activity and the rate but not the extent of myofibrillar degradation, suggesting an early effect......This study investigated the influence of post-mortem pH decline on calpain activity and myofibrillar degradation.From 80 pigs, 30 Longissimus dorsi (LD) muscles were selected on the basis of pH values at 3 h post-mortem and classified into groups of 10 as fast, intermediate and slow pH decline...... measured. A faster decrease in pH resulted in reduced level of l-calpain activity and increased autolysis of the enzyme, and hence an earlier loss of activity due to activation of l-calpain in muscles with a fast pH decline. Paralleling the l-calpain activation in muscles with a fast pH decline a higher...

  10. Incorporating Anthropogenic Influences into Fire Probability Models: Effects of Human Activity and Climate Change on Fire Activity in California.

    Science.gov (United States)

    Mann, Michael L; Batllori, Enric; Moritz, Max A; Waller, Eric K; Berck, Peter; Flint, Alan L; Flint, Lorraine E; Dolfi, Emmalee

    2016-01-01

    The costly interactions between humans and wildfires throughout California demonstrate the need to understand the relationships between them, especially in the face of a changing climate and expanding human communities. Although a number of statistical and process-based wildfire models exist for California, there is enormous uncertainty about the location and number of future fires, with previously published estimates of increases ranging from nine to fifty-three percent by the end of the century. Our goal is to assess the role of climate and anthropogenic influences on the state's fire regimes from 1975 to 2050. We develop an empirical model that integrates estimates of biophysical indicators relevant to plant communities and anthropogenic influences at each forecast time step. Historically, we find that anthropogenic influences account for up to fifty percent of explanatory power in the model. We also find that the total area burned is likely to increase, with burned area expected to increase by 2.2 and 5.0 percent by 2050 under climatic bookends (PCM and GFDL climate models, respectively). Our two climate models show considerable agreement, but due to potential shifts in rainfall patterns, substantial uncertainty remains for the semiarid inland deserts and coastal areas of the south. Given the strength of human-related variables in some regions, however, it is clear that comprehensive projections of future fire activity should include both anthropogenic and biophysical influences. Previous findings of substantially increased numbers of fires and burned area for California may be tied to omitted variable bias from the exclusion of human influences. The omission of anthropogenic variables in our model would overstate the importance of climatic ones by at least 24%. As such, the failure to include anthropogenic effects in many models likely overstates the response of wildfire to climatic change.

  11. Incorporating Anthropogenic Influences into Fire Probability Models: Effects of Human Activity and Climate Change on Fire Activity in California.

    Directory of Open Access Journals (Sweden)

    Michael L Mann

    Full Text Available The costly interactions between humans and wildfires throughout California demonstrate the need to understand the relationships between them, especially in the face of a changing climate and expanding human communities. Although a number of statistical and process-based wildfire models exist for California, there is enormous uncertainty about the location and number of future fires, with previously published estimates of increases ranging from nine to fifty-three percent by the end of the century. Our goal is to assess the role of climate and anthropogenic influences on the state's fire regimes from 1975 to 2050. We develop an empirical model that integrates estimates of biophysical indicators relevant to plant communities and anthropogenic influences at each forecast time step. Historically, we find that anthropogenic influences account for up to fifty percent of explanatory power in the model. We also find that the total area burned is likely to increase, with burned area expected to increase by 2.2 and 5.0 percent by 2050 under climatic bookends (PCM and GFDL climate models, respectively. Our two climate models show considerable agreement, but due to potential shifts in rainfall patterns, substantial uncertainty remains for the semiarid inland deserts and coastal areas of the south. Given the strength of human-related variables in some regions, however, it is clear that comprehensive projections of future fire activity should include both anthropogenic and biophysical influences. Previous findings of substantially increased numbers of fires and burned area for California may be tied to omitted variable bias from the exclusion of human influences. The omission of anthropogenic variables in our model would overstate the importance of climatic ones by at least 24%. As such, the failure to include anthropogenic effects in many models likely overstates the response of wildfire to climatic change.

  12. Measuring and influencing physical activity with smartphone technology: a systematic review.

    Science.gov (United States)

    Bort-Roig, Judit; Gilson, Nicholas D; Puig-Ribera, Anna; Contreras, Ruth S; Trost, Stewart G

    2014-05-01

    Rapid developments in technology have encouraged the use of smartphones in physical activity research, although little is known regarding their effectiveness as measurement and intervention tools. This study systematically reviewed evidence on smartphones and their viability for measuring and influencing physical activity. Research articles were identified in September 2013 by literature searches in Web of Knowledge, PubMed, PsycINFO, EBSCO, and ScienceDirect. The search was restricted using the terms (physical activity OR exercise OR fitness) AND (smartphone* OR mobile phone* OR cell phone*) AND (measurement OR intervention). Reviewed articles were required to be published in international academic peer-reviewed journals, or in full text from international scientific conferences, and focused on measuring physical activity through smartphone processing data and influencing people to be more active through smartphone applications. Two reviewers independently performed the selection of articles and examined titles and abstracts to exclude those out of scope. Data on study characteristics, technologies used to objectively measure physical activity, strategies applied to influence activity; and the main study findings were extracted and reported. A total of 26 articles (with the first published in 2007) met inclusion criteria. All studies were conducted in highly economically advantaged countries; 12 articles focused on special populations (e.g. obese patients). Studies measured physical activity using native mobile features, and/or an external device linked to an application. Measurement accuracy ranged from 52 to 100% (n = 10 studies). A total of 17 articles implemented and evaluated an intervention. Smartphone strategies to influence physical activity tended to be ad hoc, rather than theory-based approaches; physical activity profiles, goal setting, real-time feedback, social support networking, and online expert consultation were identified as the most useful

  13. Dating the period when intensive anthropogenic activity began to influence the Sanjiang Plain, Northeast China

    Science.gov (United States)

    Cong, Jinxin; Gao, Chuanyu; Zhang, Yan; Zhang, Shaoqing; He, Jiabao; Wang, Guoping

    2016-02-01

    Dating the start of intensive anthropogenic influence on ecosystems is important for identifying the conditions necessary for ecosystem recovery. However, few studies have focused on determining when anthropogenic influences on wetland began through sedimentary archives. To fill this critical gap in our knowledge, combustion sources and emission intensities, reconstructed via black carbon (BC) and polycyclic aromatic hydrocarbons (PAHs) were analyzed in two wetlands in the Sanjiang Plain in Northeast China. 14C provided age control for the sedimentary records. By combining previous sedimentary and archaeological studies, we attempt to date the beginning of intensive anthropogenic influences on the Sanjiang Plain. Our results showed that BC deposition fluxes increased from 0.02 to 0.7 g C/m2.yr during the last 10,000 years. An upward trend was apparent during the last 500 years. Before 1200 cal yr BP, human activities were minor, such that the wetland ecosystem in the Sanjiang Plain before this period may represent the reference conditions that for the recovery of these wetlands. As the human population increased after 1200 cal yr BP, combustion sources changed and residential areas became a major source of BC and PAHs. In this way, the wetland ecosystem gradually became more heavily influenced by human activities.

  14. The impact of active and passive peer influence on young adult smoking: an experimental study.

    Science.gov (United States)

    Harakeh, Zeena; Vollebergh, Wilma A M

    2012-03-01

    Peers influence adolescent and young adult smoking, but little is known about the underlying mechanisms. It is necessary to understand whether the current assumption of peer pressure is valid, or whether an alternative explanation as imitation is more appropriate. We examined whether passive (imitation) and/or active (pressure) peer influence affects young adult smoking. An experiment was conducted among 68 daily-smoking students aged 16-24. The actual study aim was masked. Participants had to do a 30-min music task with a confederate. The experiment consisted of a 2 (smoking condition: confederate smokes or not) by 2 (pressure condition: confederate offers the participant a cigarette or not) factorial design, resulting in four conditions: (1) no smoking and no pressure (N=15); (2) smoking but no pressure (N=16); (3) pressure but no smoking (N=20); and (4) smoking and pressure (N=17). The primary outcome tested was the total number of cigarettes smoked during this music assignment. Peer smoking significantly predicted the total number of cigarettes smoked by young adults while peer pressure did not. The interaction effect of peer pressure and peer smoking was not significant. Peer pressure did not have a significant additional contribution, over and above smoking of the peer. Passive (imitation) peer influence affected young adult smoking rather than active (pressure) peer influence. Thus, smoking cessation efforts should aim at preventing interaction with smoking peers and raising awareness about its impact. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  15. The influence of dairy consumption and physical activity on ultrasound bone measurements in Flemish children.

    Science.gov (United States)

    De Smet, Stephanie; Michels, Nathalie; Polfliet, Carolien; D'Haese, Sara; Roggen, Inge; De Henauw, Stefaan; Sioen, Isabelle

    2015-03-01

    The study's aim was to analyse whether children's bone status, assessed by calcaneal ultrasound measurements, is influenced by dairy consumption and objectively measured physical activity (PA). Moreover, the interaction between dairy consumption and PA on bone mass was studied. Participants of this cross-sectional study were 306 Flemish children (6-12 years). Body composition was measured with air displacement plethysmography (BodPod), dairy consumption with a Food Frequency Questionnaire, PA with an accelerometer (only in 234 of the 306 children) and bone mass with quantitative ultrasound, quantifying speed of sound (SOS), broadband ultrasound attenuation (BUA) and Stiffness Index (SI). Regression analyses were used to study the associations between dairy consumption, PA, SOS, BUA and SI. Total dairy consumption and non-cheese dairy consumption were positively associated with SOS and SI, but no significant association could be demonstrated with BUA. In contrast, milk consumption, disregarding other dairy products, had no significant effect on calcaneal bone measurements. PA [vigorous PA, moderate to vigorous physical activity (MVPA) and counts per minute] was positively associated and sedentary time was negatively associated with BUA and SI, but no significant influence on SOS could be detected. Dairy consumption and PA (sedentary time and MVPA) did not show any interaction influencing bone measurements. In conclusion, even at young age, PA and dairy consumption positively influence bone mass. Promoting PA and dairy consumption in young children may, therefore, maximize peak bone mass, an important protective factor against osteoporosis later in life.

  16. Dating the period when intensive anthropogenic activity began to influence the Sanjiang Plain, Northeast China

    Science.gov (United States)

    Cong, Jinxin; Gao, Chuanyu; Zhang, Yan; Zhang, Shaoqing; He, Jiabao; Wang, Guoping

    2016-01-01

    Dating the start of intensive anthropogenic influence on ecosystems is important for identifying the conditions necessary for ecosystem recovery. However, few studies have focused on determining when anthropogenic influences on wetland began through sedimentary archives. To fill this critical gap in our knowledge, combustion sources and emission intensities, reconstructed via black carbon (BC) and polycyclic aromatic hydrocarbons (PAHs) were analyzed in two wetlands in the Sanjiang Plain in Northeast China. 14C provided age control for the sedimentary records. By combining previous sedimentary and archaeological studies, we attempt to date the beginning of intensive anthropogenic influences on the Sanjiang Plain. Our results showed that BC deposition fluxes increased from 0.02 to 0.7 g C/m2.yr during the last 10,000 years. An upward trend was apparent during the last 500 years. Before 1200 cal yr BP, human activities were minor, such that the wetland ecosystem in the Sanjiang Plain before this period may represent the reference conditions that for the recovery of these wetlands. As the human population increased after 1200 cal yr BP, combustion sources changed and residential areas became a major source of BC and PAHs. In this way, the wetland ecosystem gradually became more heavily influenced by human activities. PMID:26907560

  17. Environmental, psychological, and social influences on physical activity among Japanese adults: structural equation modeling analysis.

    Science.gov (United States)

    Ishii, Kaori; Shibata, Ai; Oka, Koichiro

    2010-08-05

    An understanding of the contributing factors to be considered when examining how individuals engage in physical activity is important for promoting population-based physical activity. The environment influences long-term effects on population-based health behaviors. Personal variables, such as self-efficacy and social support, can act as mediators of the predictive relationship between the environment and physical activity. The present study examines the direct and indirect effects of environmental, psychological, and social factors on walking, moderate-intensity activity excluding walking, and vigorous-intensity activity among Japanese adults. The participants included 1,928 Japanese adults aged 20-79 years. Seven sociodemographic attributes (e.g., gender, age, education level, employment status), psychological variables (self-efficacy, pros, and cons), social variables (social support), environmental variables (home fitness equipment, access to facilities, neighborhood safety, aesthetic sensibilities, and frequency of observing others exercising), and the International Physical Activity Questionnaire were assessed via an Internet-based survey. Structural equation modeling was conducted to determine associations between environmental, psychological, and social factors with physical activity. Environmental factors could be seen to have indirect effects on physical activity through their influence on psychological and social variables such as self-efficacy, pros and cons, and social support. The strongest indirect effects could be observed by examining the consequences of environmental factors on physical activity through cons to self-efficacy. The total effects of environmental factors on physical activity were 0.02 on walking, 0.02 on moderate-intensity activity excluding walking, and 0.05 on vigorous-intensity activity. The present study indicates that environmental factors had indirect effects on walking, moderate-intensity activity excluding walking and

  18. Environmental, psychological, and social influences on physical activity among Japanese adults: structural equation modeling analysis

    Directory of Open Access Journals (Sweden)

    Ishii Kaori

    2010-08-01

    Full Text Available Abstract Background An understanding of the contributing factors to be considered when examining how individuals engage in physical activity is important for promoting population-based physical activity. The environment influences long-term effects on population-based health behaviors. Personal variables, such as self-efficacy and social support, can act as mediators of the predictive relationship between the environment and physical activity. The present study examines the direct and indirect effects of environmental, psychological, and social factors on walking, moderate-intensity activity excluding walking, and vigorous-intensity activity among Japanese adults. Methods The participants included 1,928 Japanese adults aged 20-79 years. Seven sociodemographic attributes (e.g., gender, age, education level, employment status, psychological variables (self-efficacy, pros, and cons, social variables (social support, environmental variables (home fitness equipment, access to facilities, neighborhood safety, aesthetic sensibilities, and frequency of observing others exercising, and the International Physical Activity Questionnaire were assessed via an Internet-based survey. Structural equation modeling was conducted to determine associations between environmental, psychological, and social factors with physical activity. Results Environmental factors could be seen to have indirect effects on physical activity through their influence on psychological and social variables such as self-efficacy, pros and cons, and social support. The strongest indirect effects could be observed by examining the consequences of environmental factors on physical activity through cons to self-efficacy. The total effects of environmental factors on physical activity were 0.02 on walking, 0.02 on moderate-intensity activity excluding walking, and 0.05 on vigorous-intensity activity. Conclusions The present study indicates that environmental factors had indirect effects on

  19. Combined influence of healthy diet and active lifestyle on cardiovascular disease risk factors in adolescents.

    Science.gov (United States)

    Cuenca-García, M; Ortega, F B; Ruiz, J R; González-Gross, M; Labayen, I; Jago, R; Martínez-Gómez, D; Dallongeville, J; Bel-Serrat, S; Marcos, A; Manios, Y; Breidenassel, C; Widhalm, K; Gottrand, F; Ferrari, M; Kafatos, A; Molnár, D; Moreno, L A; De Henauw, S; Castillo, M J; Sjöström, M

    2014-06-01

    To investigate the combined influence of diet quality and physical activity on cardiovascular disease (CVD) risk factors in adolescents, adolescents (n = 1513; 12.5-17.5 years) participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence study were studied. Dietary intake was registered using a 24-h recall and a diet quality index was calculated. Physical activity was assessed by accelerometry. Lifestyle groups were computed as: healthy diet and active, unhealthy diet but active, healthy diet but inactive, and unhealthy diet and inactive. CVD risk factor measurements included cardiorespiratory fitness, adiposity indicators, blood lipid profile, blood pressure, and insulin resistance. A CVD risk score was computed. The healthy diet and active group had a healthier cardiorespiratory profile, fat mass index (FMI), triglycerides, and high-density lipoprotein cholesterol (HDL-C) levels and total cholesterol (TC)/HDL-C ratio (all P ≤ 0.05). Overall, active adolescents showed higher cardiorespiratory fitness, lower FMI, TC/HDL-C ratio, and homeostasis model assessment index and healthier blood pressure than their inactive peers with either healthy or unhealthy diet (all P ≤ 0.05). Healthy diet and active group had healthier CVD risk score compared with the inactive groups (all P ≤ 0.02). Thus, a combination of healthy diet and active lifestyle is associated with decreased CVD risk in adolescents. Moreover, an active lifestyle may reduce the adverse consequences of an unhealthy diet. © 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. Does weight status influence perceptions of physical activity barriers among African-American women?

    Science.gov (United States)

    Genkinger, Jeanine M; Jehn, Megan L; Sapun, Marcella; Mabry, Iris; Young, Deborah Rohm

    2006-01-01

    Many African-American women fail to participate in regular physical activity. Weight status may influence physical activity barriers. This study examined the frequency and type of barriers. Participants in this study were enrolled in Project EXE-L (Exercising Ladies Excel), a six-month, church-based, randomized trial of moderate-intensity physical activity based in Baltimore city and county in Maryland. Participants were composed of African-American women who attended one of the participating churches, had friends who were church members, or who lived in neighborhoods surrounding one of the churches. Individuals who were between the ages of 25 and 70 years, were not regularly physically active (defined as not engaging in moderate-intensity activity more than three times per week), and were able to participate in moderate-intensity activity met eligibility criteria to participate in the trial. Barriers to physical activity were evaluated with the Steinhardt/Dishman Barriers for Habitual Physical Activity Scale at baseline. One hundred twenty women were classified as normal weight (body mass index [BMI]: or = 30 kg/m2). Obese participants were more likely to report "lack of motivation" as a barrier compared with normal-weight participants (63% vs 31%). Normal-weight and overweight participants were more likely to report no barriers compared with the obese (31%, 0%, 5%, respectively, P<.05). Barriers for African-American women may vary by BMI status. By defining these unique barriers, effective physical activity interventions can be developed.

  1. Influence of the piezoelectric parameters on the dynamics of an active rotor

    Science.gov (United States)

    Gawryluk, Jarosław; Mitura, Andrzej; Teter, Andrzej

    2018-01-01

    The main aim of this paper is an experimental and numerical analysis of the dynamic behavior of an active rotor with three composite blades. The study focuses on developing an effective FE modeling technique of a macro fiber composite element (denoted as MFC or active element) for the dynamic tests of active structures. The active rotor under consideration consists of a hub with a drive shaft, three grips and three glass-epoxy laminate blades with embedded active elements. A simplified FE model of the macro fiber composite element exhibiting the d33 piezoelectric effect is developed using the Abaqus software package. The discussed transducer is modeled as quasi-homogeneous piezoelectric material, and voltage is applied to the opposite faces of the element. In this case, the effective (equivalent) piezoelectric constant d33* is specified. Both static and dynamic tests are performed to verify the proposed model. First, static deflections of the active blade caused by the voltage signal are determined by numerical and experimental analyses. Next, a numerical modal analysis of the active rotor is performed. The eigenmodes and corresponding eigenfrequencies are determined by the Lanczos method. The influence of the model parameters (i.e., the effective piezoelectric constant d33 *, voltage signal, angular velocity) on the dynamics of the active rotor is examined. Finally, selected numerical results are validated in experimental tests. The experimental findings demonstrate that the structural stiffening effect caused by the active element strongly depends on the value of the effective piezoelectric constant.

  2. The Influence of Some Romanian Interest Groups Upon the Activity of Government and Parliament

    Directory of Open Access Journals (Sweden)

    Bianca COBÂRZAN

    2005-10-01

    Full Text Available The paper focuses on two specific interest groups, NGOs and trade unions, and on their influence upon the government and parliament. Our paper is based on an analyze of the activity of several interest groups during the period 2002-2004 and on the results of several researches and reports published on the last years. The analyze identifies petitioning for rule making, public meetings and debates, monitoring the activity of the public institutions and participating in advisory or regulatory committees as being the most common used mechanisms to influence the government and the parliament in Romania. Also, the analyze shows that administrative procedures affect the degree of bureaucratic autonomy. Overall, the results of this brief research show some pluralist forms of the interaction between the interest groups and the public institutions.

  3. Factors that influence exercise activity among women post hip fracture participating in the Exercise Plus Program.

    Science.gov (United States)

    Resnick, Barbara; Orwig, Denise; D'Adamo, Christopher; Yu-Yahiro, Janet; Hawkes, William; Shardell, Michelle; Golden, Justine; Zimmerman, Sheryl; Magaziner, Jay

    2007-01-01

    Using a social ecological model, this paper describes selected intra- and interpersonal factors that influence exercise behavior in women post hip fracture who participated in the Exercise Plus Program. Model testing of factors that influence exercise behavior at 2, 6 and 12 months post hip fracture was done. The full model hypothesized that demographic variables; cognitive, affective, physical and functional status; pain; fear of falling; social support for exercise, and exposure to the Exercise Plus Program would influence self-efficacy, outcome expectations, and stage of change both directly and indirectly influencing total time spent exercising. Two hundred and nine female hip fracture patients (age 81.0 +/- 6.9), the majority of whom were Caucasian (97%), participated in this study. The three predictive models tested across the 12 month recovery trajectory suggest that somewhat different factors may influence exercise over the recovery period and the models explained 8 to 21% of the variance in time spent exercising. To optimize exercise activity post hip fracture, older adults should be helped to realistically assess their self-efficacy and outcome expectations related to exercise, health care providers and friends/peers should be encouraged to reinforce the positive benefits of exercise post hip fracture, and fear of falling should be addressed throughout the entire hip fracture recovery trajectory.

  4. The influence of gemfibrozil on malondialdehyde level and paraoxonase 1 activity in wistar and fisher rats.

    Science.gov (United States)

    Macan, Marija; Marija, Macan; Konjevoda, Paško; Paško, Konjevoda; Lovric, Jasna; Jasna, Lovrić; Koprivanac, Marijan; Marijan, Koprivanac; Kelava, Marta; Marta, Kelava; Vrkic, Nada; Nada, Vrkić; Bradamante, Vlasta; Vlasta, Bradamante

    2011-06-01

    There are diverse experimental data about the influence of gemfibrozil (GEM) on the production of hydrogen peroxide (H(2)O(2)) and antioxidant enzymes. We investigated the influence of GEM treatment on the production of malondialdehyde (MDA) level in tissues of normolipidaemic Wistar and Fisher rats which is an index of lipid peroxidation. Because serum paraoxonase 1 (PON1) is an important enzyme with specific protective function on metabolism of lipid peroxides, we examined the influence of GEM on PON1 activity in liver and serum. MDA level and enzyme activities were also determined 10 days after withdrawal of GEM treatment. The significantly increased levels of MDA in liver, kidney and heart of both rat strains were obtained after 3 weeks of GEM treatment. We propose two possibilities for the increase of MDA levels caused by GEM, induction of peroxisome proliferation and activities of enzymes that participated in occurrence of H(2)O(2) and possible reduction of enzyme activities including in H(2)O(2) metabolism. Ten days after withdrawal of GEM treatment, MDA levels in all tissue levels of both rat strains were less in comparison with GEM treatment. GEM caused a significant drop of PON1 activity in serum and liver of Fisher rats, and in liver of Wistar rats. We suggest that GEM, through induction of lipid peroxidation, caused the damage of hepatocytes with consequent reduction of PON1 synthesis. The increase in PON1 activity in serum and tissues of both rat strains 10 days after withdrawal of GEM treatment shows the fast recovery of enzyme synthesis. © 2011 The Authors. Basic & Clinical Pharmacology & Toxicology © 2011 Nordic Pharmacological Society.

  5. Physical activity levels of community-dwelling older adults are influenced by winter weather variables.

    Science.gov (United States)

    Jones, G R; Brandon, C; Gill, D P

    2017-07-01

    Winter weather conditions may negatively influence participation of older adults in daily physical activity (PA). Assess the influence of winter meteorological variables, day-time peak ambient temperature, windchill, humidity, and snow accumulation on the ground to accelerometer measured PA values in older adults. 50 community-dwelling older adults (77.4±4.7yrs; range 71-89; 12 females) living in Southwestern Ontario (Latitude 42.9°N Longitude 81.2° W) Canada, wore a waist-borne accelerometer during active waking hours (12h) for 7 consecutive days between February and April 2007. Hourly temperature, windchill, humidity, and snowfall accumulation were obtained from meteorological records and time locked to hourly accelerometer PA values. Regression analysis revealed significant relationships between time of day, ambient daytime high temperature and a humidity for participation in PA. Windchill temperature added no additional influence over PA acclamation already influenced by ambient day-time temperature and the observed variability in PA patterns relative to snow accumulation over the study period was too great to warrant its inclusion in the model. Most PA was completed in the morning hours and increased as the winter month's transitioned to spring (February through April). An equation was developed to adjust for winter weather conditions using temperature, humidity and time of day. Accurate PA assessment during the winter months must account for the ambient daytime high temperatures, humidity, and time of day. These older adults were more physically active during the morning hours and became more active as the winter season transitioned to spring. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Cloud-to-ground lightning activity in Colombia and the influence of topography

    Science.gov (United States)

    Aranguren, D.; López, J.; Inampués, J.; Torres, H.; Betz, H.

    2017-02-01

    Lightning activity on the Colombian mountains, where the altitude varies from 0 to more than 5000 MSL, is studied based on VLF/LF lightning detection data and using a 2012-2013 dataset. The influence of altitude is observed by evaluating cloud-to-ground lightning incidence at different altitude intervals. The relationship between ground flash density and altitude gradient vectors is studied. Results show a clear dependence of the flash density on elevation.

  7. Plasma-catalytic reforming of ethanol: influence of air activation rate and reforming temperature

    International Nuclear Information System (INIS)

    Nedybaliuk, O.A.; Chernyak, V.Ya.; Fedirchuk, I.I.; Demchina, V.P.; Bortyshevsky, V.A.; Korzh, R.V.

    2016-01-01

    This paper presents the study of the influence that air activation rate and reforming temperature have on the gaseous products composition and conversion efficiency during the plasma-catalytic reforming of ethanol. The analysis of product composition showed that the conversion efficiency of ethanol has a maximum in the studied range of reforming temperatures. Researched system provided high reforming efficiency and high hydrogen energy yield at the lower temperatures than traditional conversion technologies

  8. The influence of thyroarytenoid and cricothyroid muscle activation on vocal fold stiffness and eigenfrequencies

    OpenAIRE

    Yin, Jun; Zhang, Zhaoyan

    2013-01-01

    The influence of the thyroarytenoid (TA) and cricothyroid (CT) muscle activation on vocal fold stiffness and eigenfrequencies was investigated in a muscularly controlled continuum model of the vocal folds. Unlike the general understanding that vocal fold fundamental frequency was determined by vocal fold tension, this study showed that vocal fold eigenfrequencies were primarily determined by vocal fold stiffness. This study further showed that, with reference to the resting state of zero stra...

  9. Analysis of Factors Influencing Activity-Based Costing Applications in the Hospitality Industry in Yenagoa, Nigeria

    OpenAIRE

    Appah, Ebimobowei; Bariweni Binaebi

    2013-01-01

    This research examines the factors influencing activity-based costing application in the hospitality industry in Yenagoa, Nigeria. To achieve this objective, primary and secondary data were used. The secondary data include books, journals, periodicals, unpublished research materials and the internet and the primary data include interview and a well structured questionnaire administered to one hundred and 165 respondents in the 50 hotels sampled from the population. The data collected from the...

  10. Reciprocal Reinforcement Between Wearable Activity Trackers and Social Network Services in Influencing Physical Activity Behaviors.

    Science.gov (United States)

    Chang, Rebecca Cherng-Shiow; Lu, Hsi-Peng; Yang, Peishan; Luarn, Pin

    2016-07-05

    Wearable activity trackers (WATs) are emerging consumer electronic devices designed to support physical activities (PAs), which are based on successful behavior change techniques focusing on goal-setting and frequent behavioral feedbacks. Despite their utility, data from both recent academic and market research have indicated high attrition rates of WAT users. Concurrently, evidence shows that social support (SS), delivered/obtained via social network services or sites (SNS), could increase adherence and engagement of PA intervention programs. To date, relatively few studies have looked at how WATs and SS may interact and affect PAs. The purpose of this study was to explore how these two Internet and mobile technologies, WATs and SNS, could work together to foster sustainable PA behavior changes and habits among middle-aged adults (40-60 years old) in Taiwan. We used purposive sampling of Executive MBA Students from National Taiwan University of Science and Technology to participate in our qualitative research. In-depth interviews and focus groups were conducted with a total of 15 participants, including 9 WAT users and 6 nonusers. Analysis of the collected materials was done inductively using the thematic approach with no preset categories. Two authors from different professional backgrounds independently annotated and coded the transcripts, and then discussed and debated until consensus was reached on the final themes. The thematic analysis revealed six themes: (1) WATs provided more awareness than motivation in PA with goal-setting and progress monitoring, (2) SS, delivered/obtained via SNS, increased users' adherence and engagement with WATs and vice versa, (3) a broad spectrum of configurations would be needed to deliver WATs with appropriately integrated SS functions, (4) WAT design, style, and appearance mattered even more than those of smartphones, as they are body-worn devices, (5) the user interfaces of WATs left a great deal to be desired, and (6

  11. Influence of Atmospheric Propagation on Performance of Laser Active Imaging System

    International Nuclear Information System (INIS)

    Li Yingchun; Sun Huayan; Guo Huichao; Zhao Yun

    2011-01-01

    Atmospheric propagation has serious influence on the performance of a good designed laser active imaging system. Atmospheric attenuation and turbulence are two main effects on laser atmospheric propagation. Imaging SNR (Signal-Noise-Ratio) and resolution are two key indexes to describe the performance of a laser active imaging system. Establishing the relation between system performance index and atmospheric propagation effect is significant. The paper analyzed the relation between imaging performance and atmospheric attenuation and turbulence through simulation. And also the experiments were done under different weather to validate the conclusion of simulation.

  12. Catalytic activity of metallic nanoisland coatings. The influence of size effects on the recombination properties

    International Nuclear Information System (INIS)

    Tomilina, O A; Berzhansky, V N; Shaposhnikov, A N; Tomilin, S V

    2016-01-01

    The results of investigations of the quantum-size effects influence on selective properties of heterogeneous nanocatalysts are presents. As etalon exothermic reaction was used the reaction of atomic hydrogen recombination. The nanostructured Pd and Pt films on Teflon substrate were used as a samples of heterogeneous nanocatalysts. It was shown that for nanoparticles with various sizes the catalytic activity has the periodic dependence. It has been found that for certain sizes of nanoparticles their catalytic activity is less than that of Teflon substrate. (paper)

  13. Influence of low dose ionizing radiation on amplification and antitumor activity of LAK/TIL cells

    International Nuclear Information System (INIS)

    Liu Wei; Hou Dianjun; Qiao Jianwei; Shang Ximei; Li Jieqing

    2000-01-01

    Objective: To study the influence of low dose ionization on amplification and antitumor activity of LAK/TIL cells. Methods: TIL cells isolated from Lewis lung cancer tissues and LAK cells from spleen of tumor-bearing mouse were irradiated with different low doses of X-rays and were cultured after irradiation. Results: Low dose ionizing radiation improved the amplification volume of LAK/TIL cells, decreased the cell death ratio in amplification process, and increased the toxicity of LAK/TIL cells, Conclusions: Low dose ionizing radiation can result in amplification of biologically activated lymphocytes, and decreases the death ratio of the cells in amplification process

  14. Influence of probiotics on the growth and digestive enzyme activity of white Pacific shrimp ( Litopenaeus vannamei)

    Science.gov (United States)

    Gómez, R. Geovanny D.; Shen, M. A.

    2008-05-01

    The influence of Bacillus probiotics on the digestive enzyme activity and the growth of Litopenaeus vannamei were determined in this study. The shrimp was treated with five percentages (1.5, 3.0, 4.5, 6.0 and 7.5) of probiotics ( Bacillus spp.) supplemented to the feed and cultured for 45d. The growth measured as the weight gain at the end of culturing was significantly ( Pshrimps than that of the control (without receiving probiotics). Activities of protease and amylase, two digestive enzymes of the midgut gland and the intestine were significantly ( Pshrimp than in the control.

  15. Perceptions, Expectations, and Informal Supports Influence Exercise Activity in Frail Older Adults

    Directory of Open Access Journals (Sweden)

    Louise Broderick

    2015-04-01

    Full Text Available This study aims to explore frail older adults’ perceptions of what influences their exercise behaviors. A qualitative descriptive design was used. Semi-structured, open-ended interviews were conducted with 29 frail older adults. Thematic content analysis established the findings. Frail older adults perceive exercise as a by-product of other purposeful activities such as manual work or social activities. Progression into frailty appears to be associated with a decline in non-family support, changing traditional roles within family support networks, and lower baseline activity levels. Frail older adults perceive exercise as incidental to more purposeful activities rather than an endpoint in itself. Therefore, exercise programs concentrating on functional outcomes may be more relevant for this population. Strategies that educate and promote social support networks may also benefit frail older adults.

  16. Influence of emotional valence and arousal on the spread of activation in memory.

    Science.gov (United States)

    Jhean-Larose, Sandra; Leveau, Nicolas; Denhière, Guy

    2014-11-01

    Controversy still persists on whether emotional valence and arousal influence cognitive activities. Our study sought to compare how these two factors foster the spread of activation within the semantic network. In a lexical decision task, prime words were varied depending on the valence (pleasant or unpleasant) or on the level of emotional arousal (high or low). Target words were carefully selected to avoid semantic priming effects, as well as to avoid arousing specific emotions (neutral). Three SOA durations (220, 420 and 720 ms) were applied across three independent groups. Results indicate that at 220 ms, the effect of arousal is significantly higher than the effect of valence in facilitating spreading activation while at 420 ms, the effect of valence is significantly higher than the effect of arousal in facilitating spreading activation. These findings suggest that affect is a sequential process involving the successive intervention of arousal and valence.

  17. Built Environment Influences of Children’s Physical Activity: Examining Differences by Neighbourhood Size and Sex

    Directory of Open Access Journals (Sweden)

    Christine A. Mitchell

    2016-01-01

    Full Text Available Neighbourhoods can facilitate or constrain moderate-to-vigorous physical activity (MVPA among children by providing or restricting opportunities for MVPA. However, there is no consensus on how to define a child’s neighbourhood. This study examines the influence of the neighbourhood built environment on objectively measured MVPA among 435 children (aged 9–14 years in London (ON, Canada. As there is no consensus on how to delineate a child’s neighbourhood, a geographic information system was used to generate measures of the neighbourhood built environment at two buffer sizes (500 m and 800 m around each child’s home. Linear regression models with robust standard errors (cluster were used to analyze the relationship between built environment characteristics and average daily MVPA during non-school hours on weekdays. Sex-stratified models assessed sex-specific relationships. When accounting for individual and neighbourhood socio-demographic variables, park space and multi-use path space were found to influence children’s MVPA. Sex-stratified models found significant associations between MVPA and park space, with the 800 m buffer best explaining boys’ MVPA and the 500 m buffer best explaining girls’ MVPA. Findings emphasize that, when designing built environments, programs, and policies to facilitate physical activity, it is important to consider that the size of the neighbourhood influencing a child’s physical activity may differ according to sex.

  18. The Influence of Climacteric Symptoms on Women’s Lives and Activities

    Directory of Open Access Journals (Sweden)

    Agnieszka Bień

    2015-04-01

    Full Text Available In the present study, we performed an analysis of the influence of climacteric symptoms on women’s lives and activities, i.e. their quality of life (QoL. The study was performed between October 2011 and February 2012. It included 148 women aged 44–62. The study used a diagnostic survey with questionnaires. The research instrument was the Blatt-Kupperman index. The respondents were asked to complete a questionnaire on socio-demographic data, quality of life, and the influence of climacteric symptoms on life and its various aspects. The respondents experiencing moderate or severe climacteric symptoms also had stronger feelings of failure (p = 0.005, feeling that opportunities are still available (p = 0.002, of losing their youth and beauty (p < 0.0001, compared to those who had slight or no symptoms. The intensity of climacteric symptoms significantly affects women’s lives and activities, i.e., their QoL. The reported intensity of climacteric symptoms is influenced by the respondents’ education, residence, marital status and professional activity. The more severe the climacteric symptoms, the lower the women’s quality of life, as evidenced for example by the feeling of failure and of losing one’s youth, beauty and opportunities.

  19. Influence of biological activity on sorption by using 65Zn and 109Cd into mangrove sediment

    International Nuclear Information System (INIS)

    Sondermann, Melissa N.; Barros, Joanna F.; Suzuki, Katia N.; Bellido, Alfredo V.B.; Lopes, Ricardo T.

    2015-01-01

    Evaluation of the chemical behavior of zinc and cadmium as well as the influence of biological activity in the sorption kinetics under microcosm experiments by mangrove sediments collected in Sepetiba Bay - Rio de Janeiro was carried out. The mentioned area was well contaminated due to the leaching from the tailing pile by the abandoned zinc processing company Inga Mercantil. Radiotracer 65 Zn and 109 Cd were used to follow their exchange across water-sediment interfaces up to 48 hours experiments in six mangrove sediment cores. To determine the benthic activity index (BAI) the cores were treated with formaldehyde (biocide) and it was found that the presence of the radiotracers in the deeper layers of sediment without formaldehyde treatment showed clearly the influence of benthic activity retention (benthic faunal and microbial effects), since the same pattern was not found in the treated sediment. The activity values obtained for 65 Zn and 109 Cd in the untreated sediment with formaldehyde on the first centimeter were 53.79±0.28 % and 67.34±0.16 % respectively, whereas for the treated ones, were 98.72 ± 0.29 % and 98.31 ± 0.24 % respectively. Thus, it was demonstrated that the use of formaldehyde, as biological activity inhibitor, ceases the bioturbation process and allowed the accumulation along the sediment. (author)

  20. The influence of extracurricular activities on middle school students' science learning in China

    Science.gov (United States)

    Zhang, Danhui; Tang, Xing

    2017-07-01

    Informal science learning has been found to have effects on students' science learning. Through the use of secondary data from a national assessment of 7410 middle school students in China, this study explores the relationship among five types of extracurricular science activities, learning interests, academic self-concept, and science achievement. Structural equation modelling was used to investigate the influence of students' self-chosen and school-organised extracurricular activities on science achievement through mediating interests and the academic self-concept. Chi-square tests were used to determine whether there was an opportunity gap in the student's engagement in extracurricular activities. The students' volunteer and school-organised participation in extracurricular science activities had a positive and indirect influence on their science achievement through the mediating variables of their learning interests and academic self-concept. However, there were opportunity gaps between different groups of students in terms of school location, family background, and especially the mother's education level. Students from urban areas with better-educated mothers or higher socioeconomic status are more likely to access diverse science-related extracurricular activities.

  1. Influence of grain activation conditions on functional characteristics of brown rice flour.

    Science.gov (United States)

    Singh, Arashdeep; Sharma, Savita; Singh, Baljit

    2017-09-01

    Grain activation is a natural processing technique that can be used to produce modified flours without chemical modification. Functional characteristics of brown rice flour as influenced by grain activation time and temperatures were investigated. Germination temperatures at 25 ℃, 30 ℃ and 35 ℃ and time for 12, 24, 36 and 48 h significantly influenced the functional properties of flour with modification of starch, protein and high enzymatic activity. Significant decrease in the bulk density, water absorption and swelling power of brown rice flour was observed in comparison to non-germinated flour. Gel consistency and oil absorption capacity of brown rice flour increased as the grain activation time and temperature were increased. Native flour had lowest emulsion and foaming properties, while increase in grain activation time and temperature enhanced the emulsifying and foaming properties of flour. Paste clarity of native flour was 54% which was reduced to 25.17%; however, increase in germination time and temperature increased the % synersis values of germinated flour. Native flour had least gelation concentration of 12% which increased to 25% after 48 h of germination at 35 ℃. Overall, germination can be used as a natural way to modify the functional properties of brown rice flours for their utilization in variety food products.

  2. Influence of tourism and traffic on the Eurasian lynx hunting activity and daily movements

    Directory of Open Access Journals (Sweden)

    Belotti, E.

    2012-01-01

    Full Text Available Human presence influences survival of large carnivores in several ways and even outdoor activities can be a source of disturbance. As ungulate prey provide the Eurasian lynx (Lynx lynx with food for several nights and the pattern of lynx activity is mainly shaped by searching for and consuming large prey, the need to move decreases strongly while the prey is eaten. However, during the day, human activity may drive lynx to move to safe shelters and habitat features such as dense vegetation may increase tolerance. In the Bohemian Forest (Czech Republic, we found 116 prey killed by five GPS–collared lynxes. We tested whether the kill sites were located farther from roads or tourist trails than a set of randomly generated locations and whether presence of roads or tourist trails and habitat structure influenced the distance ‘kill site to daytime resting sites’. At night, with low human activity, lynxes did not avoid roads and even selected the surroundings of tourist trails. The distance ‘kill site to daytime resting sites’ correlated negatively with presence of habitat concealment and distance to tourist trails, suggesting that outdoor activities may have to be considered in lynx management plans.

  3. Analysis of the radioactivity in the 'Elguea' spa, Villa Clara, Cuba; Analisis de la radiactividad en el balneario 'Elguea' , Villa Clara, Cuba

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez G, I.M.; Zerquera, J.T.; Carrazana G, J.; Capote F, E.; Rodriguez C, G. [CPHR, La Habana (Cuba)]. e-mail: isis@cphr.edu.cu

    2006-07-01

    The 'Elguea' spa, located in the north coast of the county of Villa Clara, Cuba, is considered one of those more important spas of Latin America. The waters of this spa are rich in salts of chlorine, sodium, bromine, sulfides and its contain radon. As a result of measurements of environmental gamma dose rates carried out in the area of the spa, its were considered levels of dose between 0.13 and 2.3 mSv. The obtained results motivated that it was carried out a characterization, from the radiological point of view, of the spa. This characterization is of supreme importance to be able to evaluate the impact that it has and the discharges of its waters on the environment, as well as, those dose that the population potentially affected can receive by these discharges. With this end its were carried out quantitative determinations of those existent natural more significant radionuclides in different environmental objects coming from the area of the spa and its surroundings, as well as one characterization gamma 'in situ' of the same one. The obtained results are present in this work. (Author)

  4. Lactobacillus rhamnosus GG and its SpaC pilus adhesin modulate inflammatory responsiveness and TLR-related gene expression in the fetal human gut

    Science.gov (United States)

    Ganguli, Kriston; Collado, Maria Carmen; Rautava, Jaana; Lu, Lei; Satokari, Reetta; von Ossowski, Ingemar; Reunanen, Justus; de Vos, Willem M.; Palva, Airi; Isolauri, Erika; Salminen, Seppo; Walker, W. Allan; Rautava, Samuli

    2015-01-01

    Background Bacterial contact in utero modulates fetal and neonatal immune responses. Maternal probiotic supplementation reduces the risk of immune-mediated disease in the infant. We investigated the immunomodulatory properties of live Lactobacillus rhamnosus GG and its SpaC pilus adhesin in human fetal intestinal models. Methods TNF-α mRNA expression was measured by qPCR in a human fetal intestinal organ culture model exposed to live L. rhamnosus GG and proinflammatory stimuli. Binding of recombinant SpaC pilus protein to intestinal epithelial cells was assessed in human fetal intestinal organ culture and the human fetal intestinal epithelial cell line H4 by immunohistochemistry and immunofluorescence, respectively. TLR-related gene expression in fetal ileal organ culture after exposure to recombinant SpaC was assessed by qPCR. Results Live L. rhamnosus GG significantly attenuates pathogen-induced TNF-α mRNA expression in the human fetal gut. Recombinant SpaC protein was found to adhere to the fetal gut and to modulate varying levels of TLR-related gene expression. Conclusion The human fetal gut is responsive to luminal microbes. L. rhamnosus GG significantly attenuates fetal intestinal inflammatory responses to pathogenic bacteria. The L. rhamnosus GG pilus adhesin SpaC binds to immature human intestinal epithelial cells and directly modulates intestinal epithelial cell innate immune gene expression. PMID:25580735

  5. Analysis of the radioactivity in the 'Elguea' spa, Villa Clara, Cuba; Analisis de la radiactividad en el balneario 'Elguea' , Villa Clara, Cuba

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez G, I M; Zerquera, J T; Carrazana G, J; Capote F, E; Rodriguez C, G [CPHR, La Habana (Cuba)

    2006-07-01

    The 'Elguea' spa, located in the north coast of the county of Villa Clara, Cuba, is considered one of those more important spas of Latin America. The waters of this spa are rich in salts of chlorine, sodium, bromine, sulfides and its contain radon. As a result of measurements of environmental gamma dose rates carried out in the area of the spa, its were considered levels of dose between 0.13 and 2.3 mSv. The obtained results motivated that it was carried out a characterization, from the radiological point of view, of the spa. This characterization is of supreme importance to be able to evaluate the impact that it has and the discharges of its waters on the environment, as well as, those dose that the population potentially affected can receive by these discharges. With this end its were carried out quantitative determinations of those existent natural more significant radionuclides in different environmental objects coming from the area of the spa and its surroundings, as well as one characterization gamma 'in situ' of the same one. The obtained results are present in this work. (Author)

  6. Interaction between the Stress Phase Angle (SPA and the Oscillatory Shear Index (OSI Affects Endothelial Cell Gene Expression.

    Directory of Open Access Journals (Sweden)

    Ronny Amaya

    Full Text Available Hemodynamic forces play an important role in the non-uniform distribution of atherosclerotic lesions. Endothelial cells are exposed simultaneously to fluid wall shear stress (WSS and solid circumferential stress (CS. Due to variations in impedance (global factors and geometric complexities (local factors in the arterial circulation a time lag arises between these two forces that can be characterized by the temporal phase angle between CS and WSS (stress phase angle-SPA. Asynchronous flows (SPA close to -180° that are most prominent in coronary arteries have been associated with localization of atherosclerosis. Reversing oscillatory flows characterized by an oscillatory shear index (OSI that is great than zero are also associated with atherosclerosis localization. In this study we examined the relationship between asynchronous flows and reversing flows in altering the expression of 37 genes relevant to atherosclerosis development. In the case of reversing oscillatory flow, we observed that the asynchronous condition upregulated 8 genes compared to synchronous hemodynamics, most of them proatherogenic. Upregulation of the pro-inflammatory transcription factor NFκB p65 was confirmed by western blot, and nuclear translocation of NFκB p65 was confirmed by immunofluorescence staining. A comparative study between non-reversing flow and reversing flow found that in the case of synchronous hemodynamics, reversing flow altered the expression of 11 genes, while in the case of asynchronous hemodynamics, reversing flow altered the expression of 17 genes. Reversing flow significantly upregulated protein expression of NFκB p65 for both synchronous and asynchronous conditions. Nuclear translocation of NFκB p65 was confirmed for synchronous and asynchronous conditions in the presence of flow reversal. These data suggest that asynchronous hemodynamics and reversing flow can elicit proatherogenic responses in endothelial cells compared to synchronous

  7. Transition into daylight saving time influences the fragmentation of the rest-activity cycle

    Directory of Open Access Journals (Sweden)

    Tuulio-Henriksson Annamari

    2006-01-01

    Full Text Available Abstract Background Daylight saving time is widely adopted. Little is known about its influence on the daily rest-activity cycles. We decided to explore the effects of transition into daylight saving time on the circadian rhythm of activity. Methods We monitored the rest-activity cycles with the use of wrist-worn accelerometer on a sample of ten healthy adults for ten days around the transition into summer time. Identical protocols were carried out on the same individuals in two consecutive years, yielding data on 200 person-days for analysis in this study. Results There was no significant effect on the rest-activity cycle in the sample as a whole. Fragmentation of the rest-activity cycle was enhanced in a subgroup of persons having sleep for eight hours or less (P = 0.04 but reduced in those who preferred to sleep for more than eight hours per night (P = 0.05. The average level of motor activity was increased in persons having the morning preference for daily activity patterns (P = 0.01. Conclusion Transition into daylight saving time may have a disruptive effect on the rest-activity cycle in those healthy adults who are short-sleepers or more of the evening type.

  8. PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos

    International Nuclear Information System (INIS)

    Ellison, Corie A.; Crane, Alice L.; Bonner, Matthew R.; Knaak, James B.; Browne, Richard W.; Lein, Pamela J.; Olson, James R.

    2012-01-01

    Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure conditions in humans. The current study sought to determine the influence of PON1 genotype on the activity of blood cholinesterase as well as the effect of CPF exposure on serum PON1 in workers occupationally exposed to CPF. Saliva, blood and urine were collected from agricultural workers (n = 120) from Egypt's Menoufia Governorate to determine PON1 genotype, blood cholinesterase activity, serum PON1 activity towards chlorpyrifos-oxon (CPOase) and paraoxon (POase), and urinary levels of the CPF metabolite 3,5,6-trichloro-2-pyridinol (TCPy). The PON1 55 (P ≤ 0.05) but not the PON1 192 genotype had a significant effect on CPOase activity. However, both the PON1 55 (P ≤ 0.05) and PON1 192 (P ≤ 0.001) genotypes had a significant effect on POase activity. Workers had significantly inhibited AChE and BuChE after CPF application; however, neither CPOase activity nor POase activity was associated with ChE depression when adjusted for CPF exposure (as determined by urinary TCPy levels) and stratified by PON1 genotype. CPOase and POase activity were also generally unaffected by CPF exposure although there were alterations in activity within specific genotype groups. Together, these results suggest that workers retained the capacity to detoxify chlorpyrifos-oxon under the exposure conditions experienced by this study population regardless of PON1 genotype and activity and that effects of CPF exposure on PON1 activity are minimal. -- Highlights: ► CPF exposure resulted in an increase in TCPy and decreases in BuChE and AChE. ► CPOase activity decreased in subjects with the PON1 55LM and PON1 55 MM genotypes. ► Neither PON1 genotype nor CPOase activity had an effect on BuChE or AChE inhibition.

  9. PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos

    Energy Technology Data Exchange (ETDEWEB)

    Ellison, Corie A., E-mail: cellison@buffalo.edu [Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Crane, Alice L., E-mail: alcrane@buffalo.edu [Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Bonner, Matthew R., E-mail: mrbonner@buffalo.edu [Department of Social and Preventive Medicine, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Knaak, James B., E-mail: jbknaak@aol.com [Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Browne, Richard W., E-mail: rwbrowne@buffalo.edu [Department of Biotechnical and Clinical Laboratory Sciences, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Lein, Pamela J., E-mail: pjlein@ucdavis.edu [Department of Molecular Biosciences, University of California School of Veterinary Medicine, Davis, CA 95618 (United States); Olson, James R., E-mail: jolson@buffalo.edu [Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214 (United States); Department of Social and Preventive Medicine, State University of New York at Buffalo, Buffalo, NY 14214 (United States)

    2012-12-15

    Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure conditions in humans. The current study sought to determine the influence of PON1 genotype on the activity of blood cholinesterase as well as the effect of CPF exposure on serum PON1 in workers occupationally exposed to CPF. Saliva, blood and urine were collected from agricultural workers (n = 120) from Egypt's Menoufia Governorate to determine PON1 genotype, blood cholinesterase activity, serum PON1 activity towards chlorpyrifos-oxon (CPOase) and paraoxon (POase), and urinary levels of the CPF metabolite 3,5,6-trichloro-2-pyridinol (TCPy). The PON1 55 (P ≤ 0.05) but not the PON1 192 genotype had a significant effect on CPOase activity. However, both the PON1 55 (P ≤ 0.05) and PON1 192 (P ≤ 0.001) genotypes had a significant effect on POase activity. Workers had significantly inhibited AChE and BuChE after CPF application; however, neither CPOase activity nor POase activity was associated with ChE depression when adjusted for CPF exposure (as determined by urinary TCPy levels) and stratified by PON1 genotype. CPOase and POase activity were also generally unaffected by CPF exposure although there were alterations in activity within specific genotype groups. Together, these results suggest that workers retained the capacity to detoxify chlorpyrifos-oxon under the exposure conditions experienced by this study population regardless of PON1 genotype and activity and that effects of CPF exposure on PON1 activity are minimal. -- Highlights: ► CPF exposure resulted in an increase in TCPy and decreases in BuChE and AChE. ► CPOase activity decreased in subjects with the PON1 55LM and PON1 55 MM genotypes. ► Neither PON1 genotype nor CPOase activity had an effect on BuChE or AChE inhibition.

  10. Topographic Transmissions and How To Talk About Them: The Case of the Southern Spa in Nineteenth-Century Russian Fiction

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    Benjamin Morgan

    2014-10-01

    Full Text Available The Caucasian spa resort is a significant setting in Russian literature of the nineteenth century. This paper will trace the origins and evolution of Russian fictional writing about watering places like Piatigorsk and Kislovodsk from romanticism until the turn of the twentieth century. At the same time it will consider the semiotic theories of Iurii Lotman’s Tartu-Moscow School and the ‘transtextual’ apparatus of the French narratologist Gérard Genette as ‘toolboxes’ for work on place in narrative.

  11. Impact of serum SP-A and SP-D levels on comparison and prognosis of idiopathic pulmonary fibrosis

    Science.gov (United States)

    Wang, Kai; Ju, Qing; Cao, Jing; Tang, Wenze; Zhang, Jian

    2017-01-01

    Abstract Background and objective: Idiopathic pulmonary fibrosis (IPF) has a poor prognosis in general; however, it is heterogeneous to detect relative biomarkers for predicting the disease progression. Serum biomarkers can be conveniently collected to detect and help to differentially diagnose IPF and predict IPF prognosis. This meta-analysis aimed to evaluate the use of serum surfactant proteins A and D (SP-A and SP-D) for differential diagnosis and prognosis of IPF. Methods: Relevant articles were searched in PubMed, Embase, and Chinese National Knowledge Infrastructure databases and reviewed by 2 independent readers. Standard mean difference (SMD) and 95% confidence interval (CI) were calculated to assess the difference in serum levels of SP-A/D among patients with IPF, when compared to patients with non-IPF interstitial lung disease (ILD), pulmonary infection, and healthy control. Hazard ratio (HR) and 95% CI were used to compare the relative risk of mortality. Results: Twenty-one articles (totalling 1289 IPF patients) were included in final meta-analysis. Serum SP-A levels were significantly higher in patients with IPF than in patients with non-IPF ILD (SMD: 1.108 [0.584, 1.632], P infection (SMD: 1.320 [0.999, 1.640], P SMD: 2.802 [1.901, 3.702], P SMD: 0.459 [−0.000, 0.919], P = .050). Serum SP-D levels were significantly higher in patients with IPF than in patients with pulmonary infection (SMD: 1.308 [0.813, 1.803], P SMD: 2.235 [1.739, 2.731], P < .001). Risk of death in patients with IPF and elevated serum SP-A was increased 39% compared to patients with low SP-A groups. Elevated SP-D increased risk by 111% when compared to low SP-D. In acute exacerbation of IPF, serum SP-A/D were higher than those in stable stage. The comparisons and prognosis might be different in Asian and Caucasian patients. Conclusions: Serum SP-A/D detection might be useful for differential diagnosis and prediction of survival in patients with IPF. PMID:28591049

  12. The influence of activities and nutrition status to university students' achievements

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    Fathonah, Siti

    2018-03-01

    The purpose of this research is to analyse the influence of activity and nutrition status to the achievement of students from Engineering Faculty of UNNES. The subject of this research is the students of Engineering Faculty of UNNES. Using proportional random sampling, there are 5% (214 students of 2015 batch) taken as the samples of the research. The methods of collecting the data were using documentation from akademik.unnes.ac.id on students' achievement, questionnaire to ask upon students' activity, and BMI measurement for nutrition status. The data analysis was using percentage description, chi-square analysis, and regression. The data obtained that the average grade points of engineering students are satisfying in the level of 3.29 with light activities with the energy of 2.220 kkal. The average sleeping time of the students were 5.68 hours, whereas the total of their studying and private activity were 18.18 hours. The status of students' nutrition is Normal weight with the details of 64.2% of students are Normal weight, 23.5% of them are wasting, 4.0% are overweight, and 5.2% are obesity. The activity and nutrition status were proven not significantly influencing students grade point of achievements. The suggestions proposed by the researcher are 1) the students need to increase their sleeping time to be 6-9 hours, and they need to habituate themselves in working out at least 3 times a week in 30 - 45 minutes, and 2) further research on nutrition status and students' achievements can focus on the influence of food consumption and students' clean lifestyle.

  13. Dual-Task Performance: Influence of Frailty, Level of Physical Activity, and Cognition.

    Science.gov (United States)

    Giusti Rossi, Paulo; Pires de Andrade, Larissa; Hotta Ansai, Juliana; Silva Farche, Ana Claudia; Carnaz, Leticia; Dalpubel, Daniela; Ferriolli, Eduardo; Assis Carvalho Vale, Francisco; de Medeiros Takahashi, Anielle Cristhine

    2018-03-08

    Cognition and level of physical activity have been associated with frailty syndrome. The development of tools that assess deficits related to physical and cognitive frailties simultaneously are of common interest. However, little is known about how much these aspects influence the performance of dual-task tests. Our aims were (a) to verify the influence of frailty syndrome and objectively measured physical activity and cognition on the Timed Up and Go (TUG) test and Timed Up and Go associated with dual-task (TUG-DT) performances; and (b) to compare TUG and TUG-DT performances between older adults who develop frailty syndrome. Sixty-four community-dwelling older adults were divided into frail, prefrail, and nonfrail groups, according to frailty phenotype. Assessments included anamnesis, screening of frailty syndrome, cognitive assessment (Addenbrooke's cognitive examination), placement of a triaxial accelerometer to assess level of physical activity, and TUG and TUG-DT (TUG associated with a motor-cognitive task of calling a phone number) performances. After 7 days, the accelerometer was removed. A multiple linear regression was applied to identify which independent variables could explain performances in the TUG and TUG-DT. Subsequently, the analysis of covariance test, adjusted for age, cognition, and level of physical activity covariates, was used to compare test performances. There were no differences in cognition between groups. Significant differences in the level of physical activity were found in the frail group. Compared with the frail group, the nonfrail group required less time and fewer steps to complete the TUG. Regarding the TUG-DT, cognition and age influenced the time spent and number of steps, respectively; however, no differences were found between groups. Frail older adults presented worse performance in the TUG when compared with nonfrail older adults. The dual-task test does not differentiate older adults with frailty syndrome, regardless of

  14. The influence of ergonomic devices on mechanical load during patient handling activities in nursing homes.

    Science.gov (United States)

    Koppelaar, Elin; Knibbe, Hanneke J J; Miedema, Harald S; Burdorf, Alex

    2012-07-01

    Mechanical load during patient handling activities is an important risk factor for low back pain among nursing personnel. The aims of this study were to describe required and actual use of ergonomic devices during patient handling activities and to assess the influence of these ergonomic devices on mechanical load during patient handling activities. For each patient, based on national guidelines, it was recorded which specific ergonomic devices were required during distinct patient handling activities, defined by transferring a patient, providing personal care, repositioning patients in the bed, and putting on and taking off anti-embolism stockings. During real-time observations over ~60 h among 186 nurses on 735 separate patient handling activities in 17 nursing homes, it was established whether ergonomic devices were actually used. Mechanical load was assessed through observations of frequency and duration of a flexed or rotated trunk >30° and frequency of pushing, pulling, lifting or carrying requiring forces 230 N from start to end of each separate patient handling activity. The number of patients and nurses per ward and the ratio of nurses per patient were used as ward characteristics with potential influence on mechanical load. A mixed-effect model for repeated measurements was used to determine the influence of ergonomic devices and ward characteristics on mechanical load. Use of ergonomic devices was required according to national guidelines in 520 of 735 (71%) separate patient handling activities, and actual use was observed in 357 of 520 (69%) patient handling activities. A favourable ratio of nurses per patient was associated with a decreased duration of time spent in awkward back postures during handling anti-embolism stocking (43%), patient transfers (33%), and personal care of patients (24%) and also frequency of manually lifting patients (33%). Use of lifting devices was associated with a lower frequency of forces exerted (64%), adjustable bed and

  15. Influence of post-treatment strategies on the properties of activated chars from broiler manure.

    Science.gov (United States)

    Lima, Isabel M; Boykin, Debbie L; Thomas Klasson, K; Uchimiya, Minori

    2014-01-01

    There are a myriad of carbonaceous precursors that can be used advantageously to produce activated carbons or chars, due to their low cost, availability and intrinsic properties. Because of the nature of the raw material, production of granular activated chars from broiler manure results in a significant ash fraction. This study was conducted to determine the influence of several pre- and post-treatment strategies in various physicochemical and adsorptive properties of the resulting activated chars. Pelletized samples of broiler litter and cake were pyrolyzed at 700 °C for 1h followed by a 45 min steam activation at 800 °C at different water flow rates from 1 to 5 mL min(-1). For each activation strategy, samples were either water-rinsed or acid-washed and rinsed or used as is (no acid wash/rinse). Activated char's physicochemical and adsorptive properties towards copper ions were selectively affected by both pre- and post-treatments. Percent ash reduction after either rinsing or acid washing ranged from 1.1 to 15.1% but washed activated chars were still alkaline with pH ranging from 8.4 to 9.1. Acid washing or water rinsing had no significant effect in the ability of the activated char to adsorb copper ions, however it significantly affected surface area, pH, ash content and carbon content. Instead, manure type (litter versus cake) and the activation water flow rate were determining factors in copper ion adsorption which ranged from 38 mg g(-1) to 104 mg g(-1) of activated char. Moreover, strong positive correlations were found between copper uptake and concentration of certain elements in the activated char such as phosphorous, sulfur, calcium and sodium. Rinsing could suffice as a post treatment strategy for ash reduction since no significant differences in the carbon properties were observed between rinsed and acid wash treatments. Published by Elsevier Ltd.

  16. Parental influences on child physical activity and screen viewing time: a population based study

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    Wolfenden Luke

    2010-10-01

    Full Text Available Abstract Background Parents can influence their children's physical activity participation and screen time.This study examined the relative significance of perceived parental barriers and self-efficacy in relation to children's physical activity participation and screen time viewing. The associations between these factors and the behaviours were analysed. Methods Cross-sectional population survey in New South Wales, Australia of parents of pre-school (N = 764, younger (Kindergarten, Grades 2 and 4; N = 1557 and older children (Grades 6, 8 and 10; N = 1665. Parents reported barriers and self-efficacy to influence their child's physical activity and screen time behaviours in a range of circumstances. Differences were examined by child's sex and age group, household income, maternal education and location of residence. The duration of physical activity and screen viewing was measured by parental report for pre-school and younger children and self-report for older children. Associations between parental factors and children's organised, non-organised and total activity and screen time were analysed. Results Cost, lack of opportunities for participation and transport problems were the barriers most often reported, particularly by low income parents and those in rural areas. The number of barriers was inversely related to children's time spent in organised activity, but not their non-organised activity. Higher parental self-efficacy was positively associated with organised physical activity in the younger and older children's groups and the non-organised activity of older children. School-age children (younger and older groups were less likely to meet physical activity guidelines when parents reported ≥4 barriers (OR 3.76, 95% CI 1.25-11.34 and OR 3.72, 95% CI 1.71-8.11 respectively. Low parental self-efficacy was also associated with the likelihood of children exceeding screen time guidelines for each age group (pre-school OR 0.62, 95% CI 0

  17. Influence of Fragrances on Human Psychophysiological Activity: With Special Reference to Human Electroencephalographic Response

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    Kandhasamy Sowndhararajan

    2016-11-01

    Full Text Available The influence of fragrances such as perfumes and room fresheners on the psychophysiological activities of humans has been known for a long time, and its significance is gradually increasing in the medicinal and cosmetic industries. A fragrance consists of volatile chemicals with a molecular weight of less than 300 Da that humans perceive through the olfactory system. In humans, about 300 active olfactory receptor genes are devoted to detecting thousands of different fragrance molecules through a large family of olfactory receptors of a diverse protein sequence. The sense of smell plays an important role in the physiological effects of mood, stress, and working capacity. Electrophysiological studies have revealed that various fragrances affected spontaneous brain activities and cognitive functions, which are measured by an electroencephalograph (EEG. The EEG is a good temporal measure of responses in the central nervous system and it provides information about the physiological state of the brain both in health and disease. The EEG power spectrum is classified into different frequency bands such as delta (0.5–4 Hz, theta (4–8 Hz, alpha (8–13 Hz, beta (13–30 Hz and gamma (30–50 Hz, and each band is correlated with different features of brain states. A quantitative EEG uses computer software to provide the topographic mapping of the brain activity in frontal, temporal, parietal and occipital brain regions. It is well known that decreases of alpha and beta activities and increases of delta and theta activities are associated with brain pathology and general cognitive decline. In the last few decades, many scientific studies were conducted to investigate the effect of inhalation of aroma on human brain functions. The studies have suggested a significant role for olfactory stimulation in the alteration of cognition, mood, and social behavior. This review aims to evaluate the available literature regarding the influence of fragrances on the

  18. Influence of Fragrances on Human Psychophysiological Activity: With Special Reference to Human Electroencephalographic Response

    Science.gov (United States)

    Sowndhararajan, Kandhasamy; Kim, Songmun

    2016-01-01

    The influence of fragrances such as perfumes and room fresheners on the psychophysiological activities of humans has been known for a long time, and its significance is gradually increasing in the medicinal and cosmetic industries. A fragrance consists of volatile chemicals with a molecular weight of less than 300 Da that humans perceive through the olfactory system. In humans, about 300 active olfactory receptor genes are devoted to detecting thousands of different fragrance molecules through a large family of olfactory receptors of a diverse protein sequence. The sense of smell plays an important role in the physiological effects of mood, stress, and working capacity. Electrophysiological studies have revealed that various fragrances affected spontaneous brain activities and cognitive functions, which are measured by an electroencephalograph (EEG). The EEG is a good temporal measure of responses in the central nervous system and it provides information about the physiological state of the brain both in health and disease. The EEG power spectrum is classified into different frequency bands such as delta (0.5–4 Hz), theta (4–8 Hz), alpha (8–13 Hz), beta (13–30 Hz) and gamma (30–50 Hz), and each band is correlated with different features of brain states. A quantitative EEG uses computer software to provide the topographic mapping of the brain activity in frontal, temporal, parietal and occipital brain regions. It is well known that decreases of alpha and beta activities and increases of delta and theta activities are associated with brain pathology and general cognitive decline. In the last few decades, many scientific studies were conducted to investigate the effect of inhalation of aroma on human brain functions. The studies have suggested a significant role for olfactory stimulation in the alteration of cognition, mood, and social behavior. This review aims to evaluate the available literature regarding the influence of fragrances on the

  19. Modulation of brain activity during action observation: influence of perspective, transitivity and meaningfulness.

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    Sébastien Hétu

    Full Text Available The coupling process between observed and performed actions is thought to be performed by a fronto-parietal perception-action system including regions of the inferior frontal gyrus and the inferior parietal lobule. When investigating the influence of the movements' characteristics on this process, most research on action observation has focused on only one particular variable even though the type of movements we observe can vary on several levels. By manipulating the visual perspective, transitivity and meaningfulness of observed movements in a functional magnetic resonance imaging study we aimed at investigating how the type of movements and the visual perspective can modulate brain activity during action observation in healthy individuals. Importantly, we used an active observation task where participants had to subsequently execute or imagine the observed movements. Our results show that the fronto-parietal regions of the perception action system were mostly recruited during the observation of meaningless actions while visual perspective had little influence on the activity within the perception-action system. Simultaneous investigation of several sources of modulation during active action observation is probably an approach that could lead to a greater ecological comprehension of this important sensorimotor process.

  20. S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity.

    Science.gov (United States)

    Zvejniece, Liga; Svalbe, Baiba; Vavers, Edijs; Makrecka-Kuka, Marina; Makarova, Elina; Liepins, Vilnis; Kalvinsh, Ivars; Liepinsh, Edgars; Dambrova, Maija

    2017-09-01

    S-phenylpiracetam is an optical isomer of phenotropil, which is a clinically used nootropic drug that improves physical condition and cognition. Recently, it was shown that S-phenylpiracetam is a selective dopamine transporter (DAT) inhibitor that does not influence norepinephrine (NE) or serotonin (5-HT) receptors. The aim of the present study was to study the effects of S-phenylpiracetam treatment on body weight gain, blood glucose and leptin levels, and locomotor activity. Western diet (WD)-fed mice and obese Zucker rats were treated daily with peroral administration of S-phenylpiracetam for 8 and 12weeks, respectively. Weight gain and plasma metabolites reflecting glucose metabolism were measured. Locomotor activity was detected in an open-field test. S-phenylpiracetam treatment significantly decreased body weight gain and fat mass increase in the obese Zucker rats and in the WD-fed mice. In addition, S-phenylpiracetam reduced the plasma glucose and leptin concentration and lowered hyperglycemia in a glucose tolerance test in both the mice and the rats. S-phenylpiracetam did not influence locomotor activity in the obese Zucker rats or in the WD-fed mice. The results demonstrate that S-phenylpiracetam reduces body weight gain and improves adaptation to hyperglycemia without stimulating locomotor activity. Our findings suggest that selective DAT inhibitors, such as S-phenylpiracetam, could be potentially useful for treating obesity in patients with metabolic syndrome with fewer adverse health consequences compared to other anorectic agents. Copyright © 2017. Published by Elsevier Inc.

  1. The influence of thyroarytenoid and cricothyroid muscle activation on vocal fold stiffness and eigenfrequencies

    Science.gov (United States)

    Yin, Jun; Zhang, Zhaoyan

    2013-01-01

    The influence of the thyroarytenoid (TA) and cricothyroid (CT) muscle activation on vocal fold stiffness and eigenfrequencies was investigated in a muscularly controlled continuum model of the vocal folds. Unlike the general understanding that vocal fold fundamental frequency was determined by vocal fold tension, this study showed that vocal fold eigenfrequencies were primarily determined by vocal fold stiffness. This study further showed that, with reference to the resting state of zero strain, vocal fold stiffness in both body and cover layers increased with either vocal fold elongation or shortening. As a result, whether vocal fold eigenfrequencies increased or decreased with CT/TA activation depended on how the CT/TA interaction influenced vocal fold deformation. For conditions of strong CT activation and thus an elongated vocal fold, increasing TA contraction reduced the degree of vocal fold elongation and thus reduced vocal fold eigenfrequencies. For conditions of no CT activation and thus a resting or slightly shortened vocal fold, increasing TA contraction increased the degree of vocal fold shortening and thus increased vocal fold eigenfrequencies. In the transition region of a slightly elongated vocal fold, increasing TA contraction first decreased and then increased vocal fold eigenfrequencies. PMID:23654401

  2. Influence of the environment in the body position attitude during the practice of the physical activity

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    Valia Alina Crespo Almeira

    2016-04-01

    Full Text Available The paper addresses the importance of postural attitude in environmental ergonomics considering that ergonomics is a multidisciplinary discipline that studies the systemic interactions between human machine in the development of different physical activities in their environment with the purpose of obtaining a state health, safety, mechanical efficiency and productivity to prevent repetitive strain injuries, positions held and musculoskeletal problems which can develop over time and can reach disabilities short or long term. Considering the influence of the environment on man to work: thermal, sound, light environments and its impact on health; anthropometric and biomechanical data: measures of bone, amplitudes segments of joint movements; the characteristics of muscular effort: The efficiency and effectiveness in physical activities in its various manifestations is contingent on first order to study the physical conditions such as; thermal environment, noise levels, air conditioning level, vibration hygienic conditions, including conditions schedules and secondly the attitude that sums the man in front of the activities which in one way or another affect job performance. It addresses the influence of postural attitude in environmental ergonomics while performing physical activities of man from the importance and prevalence of health problems related to the non-application of standards of environmental ergonomics.

  3. Influence of apolipoprotein-E gene on lipid profile, physical activity and body fat relationship

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    Thales Boaventura Rachid Nascimento

    2012-03-01

    Full Text Available Physical activity and body fat modify lipemia, and this effect seems to be influenced by apolipoprotein-E (APOE gene polymorphism. Thus, the purpose of this article was to review main results of studies that have analyzed the relation of APOE gene with physical activity and body fat on triglycerides, total cholesterol and low (LDL and high density lipoprotein (HDL concentrations. The Scientific Electronic Library Online – SciELO, Web of Science and PubMed database were used to locate the articles. The keywords used in combination were: apoe genotype, apolipoprotein-E polymorphism, physical exercise, physical activity, aerobic exercise, body fat and obesity. Originals scientific investigations performed with humans were included, and excluded those ones which involved samples with diseases, except obesity and/or lipemic disorders. It was observed a trend, that ε2 allele carriers are the ones with the greater improvements on lipemia from physical exercise. In addition, the body fat impact on the elevation of triglycerides and LDL are stronger in carriers of the ε2 and ε4 allele, respectively. Considering the small number of originals scientific investigations and their divergent results, reliable inferences can not be made about the APOE gene polymorphism influences on physical activity and body fat effect on lipemia. Thus, further studies with others populations and more volunteers for allele, as well as others exercise modalities and intensities, are necessary.

  4. Phenol removal onto novel activated carbons made from lignocellulosic precursors: influence of surface properties.

    Science.gov (United States)

    Nabais, J M Valente; Gomes, J A; Suhas; Carrott, P J M; Laginhas, C; Roman, S

    2009-08-15

    The adsorption of phenol from dilute aqueous solutions onto new activated carbons (AC) was studied. The novel activated carbon was produced from lignocellulosic (LC) precursors of rapeseed and kenaf. Samples oxidised with nitric acid in liquid phase were also studied. The results have shown the significant potential of rapeseed and kenaf for the activated carbon production. The activated carbons produced by carbon dioxide activation were mainly microporous with BET apparent surface area up to 1350 m(2)g(-1) and pore volume 0.5 cm(3)g(-1). The effects of concentration (0.1-2 mM) and pH (3-13) were studied. The phenol adsorption isotherms at 25 degrees C followed the Freundlich model with maximum adsorption capacities of approximately 80 and 50 mg g(-1) for the pristine and oxidised activated carbons, respectively. The influence of pH on the adsorption has two trends for pH below and above 10. It was possible to conclude that when phenol is predominantly in the molecular form the most probable mechanism is based on the pi-pi dispersion interaction between the phenol aromatic ring and the delocalised pi electrons present in the activated carbon aromatic structure. When phenolate is the major component the electrostatic repulsion that occurs at high pH values is the most important aspect of the adsorption mechanism.

  5. Phenol removal onto novel activated carbons made from lignocellulosic precursors: Influence of surface properties

    International Nuclear Information System (INIS)

    Valente Nabais, J.M.; Gomes, J.A.; Suhas; Carrott, P.J.M.; Laginhas, C.; Roman, S.

    2009-01-01

    The adsorption of phenol from dilute aqueous solutions onto new activated carbons (AC) was studied. The novel activated carbon was produced from lignocellulosic (LC) precursors of rapeseed and kenaf. Samples oxidised with nitric acid in liquid phase were also studied. The results have shown the significant potential of rapeseed and kenaf for the activated carbon production. The activated carbons produced by carbon dioxide activation were mainly microporous with BET apparent surface area up to 1350 m 2 g -1 and pore volume 0.5 cm 3 g -1 . The effects of concentration (0.1-2 mM) and pH (3-13) were studied. The phenol adsorption isotherms at 25 deg. C followed the Freundlich model with maximum adsorption capacities of approximately 80 and 50 mg g -1 for the pristine and oxidised activated carbons, respectively. The influence of pH on the adsorption has two trends for pH below and above 10. It was possible to conclude that when phenol is predominantly in the molecular form the most probable mechanism is based on the π-π dispersion interaction between the phenol aromatic ring and the delocalised π electrons present in the activated carbon aromatic structure. When phenolate is the major component the electrostatic repulsion that occurs at high pH values is the most important aspect of the adsorption mechanism.

  6. The length of a lantibiotic hinge region has profound influence on antimicrobial activity and host specificity

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    Liang eZhou

    2015-01-01

    Full Text Available Lantibiotics are ribosomally synthesized (methyllanthionine containing peptides which can efficiently inhibit the growth of Gram-positive bacteria. As lantibiotics kill bacteria efficiently and resistance to them is difficult to be obtained, they have the potential to be used in many applications, e.g. in pharmaceutical industry or food industry. Nisin can inhibit the growth of Gram-positive bacteria by binding to lipid II and by making pores in their membrane. The C-terminal part of nisin is known to play an important role during translocation over the membrane and forming pore complexes. However, as the thickness of bacterial membranes varies between different species and environmental conditions, this property could have an influence on the pore forming activity of nisin. To investigate this, the so-called hinge region of nisin (residues NMK was engineered to vary from one to six amino acid residues and specific activity against different indicators was compared. Antimicrobial activity in liquid culture assays showed that wild type nisin is most active, while truncation of the hinge region dramatically reduced the activity of the peptide. However, one or two amino acids extensions showed only slightly reduced activity against most indicator strains. Notably, some variants (+2, +1, -1, -2 exhibited higher antimicrobial activity than nisin in agar well diffusion assays against Lactococcus lactis MG1363, Listeria monocytogenes, Enterococcus faecalis VE14089, Bacillus sporothermodurans IC4 and Bacillus cereus 4153 at certain temperatures.

  7. Influence of the particle size of activated mineral carbon on the phenol and chlorophenol adsorption

    International Nuclear Information System (INIS)

    Garcia M, A.

    2001-01-01

    Water pollution by phenolic compounds is a problem that requires a solution since these phenolic compounds are not completely biodegradable, they accumulate through the food chains and they are quite toxic when enter in contact with living organisms. In human beings, ingestion or contact of the skin with this type of compounds produces irritation and damages mainly to the liver and kidneys. In fact, the Environmental Protection Agency of the United States (EPA assigned nine phenolic compounds among the 275 most toxic substances in 1991. Phenols are found in wastewater from agriculture and industry, because phenolic compounds are used as pesticides and in diverse industrial activities. The treatment of this type of water is not simple because they are generally composed of a mixture of residuals with different chemical nature A useful method for the removal of phenols is the adsorption by activated carbon, since this material has a great surface area and it can be regenerated. The adsorption process depends, among other factors, on the activated carbon characteristics. When they are modified, their capacity to remove pollutants from the water changes. The effect of activated carbon particle size on the removal of phenolic compounds has not been completely studied. Therefore, the aim of this work was to determine the influence of the mineral activated carbon particle size on the phenol and 4-chloro phenol adsorption in aqueous solution, on adsorption column system. The results of the present work indicate that the mineral activated carbon particle size has a very important influence on the adsorption of phenol and 4-chloro phenol. When the particles were smaller, the retention quantities of phenol and 4-chloro phenol increased. This behavior was related to the particle characteristics of the mineral activated carbon such as surface area and pore volume, while other factors such as elementary composition of the activated carbon did not influence the adsorption process

  8. Informal education and youth leisure. The influence of friends in the abandonment of physical sport activity

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    M Angeles Valdemoros San Emeterio

    2012-07-01

    Full Text Available The goal of this research is to determine whether the importance granted by friends to physical-sport activities influences adolescents’ dropout of physical-sport.A methodological triangulation was conducted, using quantitative and qualitative techniques. In the quantitative technique. the final sample comprised 1978 subjects, 51.7% girls and 48.3% boys. Descriptive analysis, inferential analysis (Cramer’s V, and multinomial regression analysis were performed on the data collected with the questionnaire.In the qualitative technique, four focus groups (n = 41were employed: parents, Physical Education teachers, teachers from other areas, and adolsescents. Results show that girls’ dropout rate is three times higher than that of the boys, and they are four times more likely to abandon this lifestyle than boys.The peer group is one of the most powerful informal education agents to influence adolescents’ physical-sport practice, but its influence varies by sex. If friends grant much, some, or very much importance to physical-sport practice, girls are less likely to drop out of such practice, but when boys’ friends grant no importance to physical-sport activity, they are five times more likely to drop out.

  9. Local Factors Influencing The Increase In Development Activity In Selected Cities Of Poland

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    Antczak-Stępniak Agata

    2015-09-01

    Full Text Available Development activity in Poland began to increase in the 1990's as a result of market-oriented reforms, with the process continuing to this day. The beginnings were, however, not easy due to, among others, the absence of many important legal regulations and the lack of commercial financing. The situation changed in the second half of the 1990's, positively affecting residential development activity. The years 2008 - 2009 were particularly relevant in the course of the studied trend as a sharp increase in the number of completed developer-built residential dwelling units was recorded at this time. After this period, a decline in the number of dwelling units completed by developers was recorded, which indicates its strong dependence on changes in the economic environment. Fluctuations in the number of dwelling units completed by developers were also visible before Poland's accession to the European Union. This means that the diversity of development activity is influenced by many factors.

  10. Normally occurring environmental and behavioral influences on gene activity: from central dogma to probabilistic epigenesis.

    Science.gov (United States)

    Gottlieb, G

    1998-10-01

    The central dogma of molecular biology holds that "information" flows from the genes to the structure of the proteins that the genes bring about through the formula DNA-->RNA-->Protein. In this view, a set of master genes activates the DNA necessary to produce the appropriate proteins that the organism needs during development. In contrast to this view, probabilistic epigenesis holds that necessarily there are signals from the internal and external environment that activate DNA to produce the appropriate proteins. To support this view, a substantial body of evidence is reviewed showing that external environmental influences on gene activation are normally occurring events in a large variety of organisms, including humans. This demonstrates how genes and environments work together to produce functional organisms, thus extending the author's model of probabilistic epigenesis.

  11. Influence of Pyrolytic Biochar on Settleability and Denitrification of Activated Sludge Process

    Institute of Scientific and Technical Information of China (English)

    Xiao-feng Sima; Bing-bing Li; Hong Jiang

    2017-01-01

    Biochar is a massively produced by-product of biomass pyrolysis to obtain renewable energy and has not been fully used.Incomplete separation of sludge and effluent and insufficient denitrification of sewage are two of main factors that influence the efficiency of activated sludge process.In this work,we proposed a new utilization of biochar and investigated the effect of biochar addition on the performance of settleability and denitrification of activated sludge.Results show that the addition of biochar can improve the settleability of activated sludge by changing the physicochemical characteristics of sludge (e.g.,flocculating ability,zeta-potential,hydrophobicity,and extracellular polymeric substances constituents).Moreover,the dissolved organic carbon released from biochar obtained at lower pyrolysis temperature can improve the nitrate removal efficiency to a certain extent.

  12. The influence of conformational fluctuations on enzymatic activity: modelling the functional motion of β-secretase

    International Nuclear Information System (INIS)

    Neri, M; Cascella, M; Micheletti, C

    2005-01-01

    Considerable insight into the functional activity of proteins and enzymes can be obtained by studying the low energy conformational distortions that the biopolymer can sustain. We carry out the characterization of these large scale structural changes for a protein of considerable pharmaceutical interest, the human β-secretase. Starting from the crystallographic structure of the protein, we use the recently introduced β-Gaussian model to identify, with negligible computational expenditure, the most significant distortions occurring in thermal equilibrium and the associated timescales. The application of this strategy helps us to gain considerable insight into the putative functional movements and, furthermore, allows us to identify a handful of key regions in the protein which have an important mechanical influence on the enzymatic activity despite being spatially distant from the active site. The results obtained within the Gaussian model are validated through an extensive comparison against an all-atom molecular dynamics simulation

  13. Physical activity, but not sedentary time, influences bone strength in late adolescence.

    Science.gov (United States)

    Tan, Vina Ps; Macdonald, Heather M; Gabel, Leigh; McKay, Heather A

    2018-03-20

    Physical activity is essential for optimal bone strength accrual, but we know little about interactions between physical activity, sedentary time, and bone outcomes in older adolescents. Physical activity (by accelerometer and self-report) positively predicted bone strength and the distal and midshaft tibia in 15-year-old boys and girls. Lean body mass mediated the relationship between physical activity and bone strength in adolescents. To examine the influence of physical activity (PA) and sedentary time on bone strength, structure, and density in older adolescents. We used peripheral quantitative computed tomography to estimate bone strength at the distal tibia (8% site; bone strength index, BSI) and tibial midshaft (50% site; polar strength strain index, SSI p ) in adolescent boys (n = 86; 15.3 ± 0.4 years) and girls (n = 106; 15.3 ± 0.4 years). Using accelerometers (GT1M, Actigraph), we measured moderate-to-vigorous PA (MVPA Accel ), vigorous PA (VPA Accel ), and sedentary time in addition to self-reported MVPA (MVPA PAQ-A ) and impact PA (ImpactPA PAQ-A ). We examined relations between PA and sedentary time and bone outcomes, adjusting for ethnicity, maturity, tibial length, and total body lean mass. At the distal tibia, MVPA Accel and VPA Accel positively predicted BSI (explained 6-7% of the variance, p accounting for lean mass. Sedentary time did not independently predict bone strength at either site. Greater tibial bone strength in active adolescents is mediated, in part, by lean mass. Despite spending most of their day in sedentary pursuits, adolescents' bone strength was not negatively influenced by sedentary time.

  14. Influence of Echinacea purpurea intake during pregnancy on fetal growth and tissue angiogenic activity.

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    Ewa Sommer

    2008-04-01

    Full Text Available The process of angiogenesis and control of blood vessels sprouting are fundamental to human health, as they play key roles in many physiological and pathological conditions. Intake of different pharmaceuticals with antiangiogenic activity by pregnant women may lead to severe developmental disturbances as it was described in case of thalidomide. It may also cause immunomodulatory effects as it was shown for antibiotics, theobromine, caffeic acid or catechins on the pregnant mice model. At present, Echinacea purpurea-based phytoceuticals are among the most popular herbals in the marketplace. Many compounds of Echinacea extracts (polysaccharides, alkamides, polyphenols, glycoproteins exert immunomodulatory, anti-oxidative and anti-inflammatory activity. Echinacea is one of the most powerful and effective remedies against many kinds of bacterial and viral infections. In previous studies we shown significant inhibitory effect of the Echinacea purpurea based remedy on tumour angiogenic activity using cutaneous angiogenesis test, and an inhibitory effect on L-1 sarcoma growth was observed . The aim of the present study was to establish whether pharmaceuticals containing alcoholic extracts of Echinacea purpurea given to pregnant mice influence angiogenic activity and tissue VEGF and bFGF production of their fetuses. We showed that angiogenic activity of tissue homogenates was increased in Esberitox group and diminished in case of Immunal forte as compared to standard diet group. In case of Echinapur group we did not find significant differences in angiogenic activity. VEGF and bFGF concentration were lower in all groups compared to the control. In the case of Echinapur and Esberitox number of fetuses in one litter were slightly lower as compared to control group, but the difference is on the border of statistical significance. In conclusion, there is some possibility that pharmaceuticals containing Echinacea purpurea might influence fetal development in

  15. Smooth pursuit adaptation (SPA exhibits features useful to compensate changes in the properties of the smooth pursuit eye movement system due to usage.

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    Suryadeep eDash

    2013-10-01

    Full Text Available Smooth-pursuit adaptation (SPA refers to the fact that pursuit gain in the early, still open-loop response phase of the pursuit eye movement can be adjusted based on experience. For instance, if the target moves initially at a constant velocity for approximately 100-200ms and then steps to a higher velocity, subjects learn to up-regulate the pursuit gain associated with the initial target velocity (gain-increase SPA in order to reduce the retinal error resulting from the velocity step. Correspondingly, a step to a lower target velocity leads to a decrease in gain (gain-decrease SPA. In this study we demonstrate that the increase in peak eye velocity during gain-increase SPA is a consequence of expanding the duration of the eye acceleration profile while the decrease in peak velocity during gain-decrease SPA results from reduced peak eye acceleration but unaltered duration. Furthermore, we show that carrying out stereotypical smooth pursuit eye movements elicited by constant velocity target ramps for several hundred trials (= test of pursuit resilience leads to a clear drop in initial peak acceleration, a reflection of oculomotor and/ or cognitive fatigue. However, this drop in acceleration gets compensated by an increase in the duration of the acceleration profile, thereby keeping initial pursuit gain constant. The compensatory expansion of the acceleration profile in the pursuit resilience experiment is reminiscent of the one leading to gain-increase SPA, suggesting that both processes tap one and the same neuronal mechanism warranting a precise acceleration/ duration trade-off. Finally, we show that the ability to adjust acceleration duration during pursuit resilience depends on the integrity of the oculomotor vermis (OMV as indicated by the complete loss of the duration adjustment following a surgical lesion of the OMV in one rhesus monkey we could study.

  16. [Estimation of effective doses derived from radon in selected SPA centers that use geothermal waters based on the information of radon concentrations].

    Science.gov (United States)

    Walczak, Katarzyna; Zmyślony, Marek

    2013-01-01

    Geothermal waters contain, among other components, soluble radon gas. Alpha radioactive radon is a health hazard to humans, especially when it gets into the respiratory tract. SPA facilities that use geothermal water can be a source of an increased radiation dose to people who stay there. Based on the available literature concerning radon concentrations, we assessed exposure to radon among people - workers and visitors of Spa centers that use geothermal waters. Radon concentrations were analyzed in 17 geothermal centers: in Greece (3 centers), Iran (5), China (4) and India (5). Doses recived by people in the SPA were estimated using the formula that 1 hour exposure to 1 Bq/m3 of radon concentration and equilibrium factor F = 0.4 corresponds to an effective dose of 3.2 nSv. We have found that radon levels in SPAs are from a few to several times higher than those in confined spaces, where geothermal waters are not used (e.g., residential buildings). In 82% of the analyzed SPAs, workers may receive doses above 1 mSv/year. According to the relevant Polish regulations, people receiving doses higher than 1 mSv/year are included in category B of radiation exposure and require regular dosimetric monitoring. Doses received by SPA visitors are much lower because the time of their exposure to radon released from geothermal water is rather short. The analysis of radon concentration in SPA facilities shows that the radiological protection of people working with geothermal waters plays an important role. It seems reasonable to include SPA workers staying close to geotermal waters into a dosimetric monitoring program.

  17. Estimation of effective doses derived from radon in selected SPA centers that use geothermal waters based on the information of radon concentrations

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    Katarzyna Walczak

    2013-04-01

    Full Text Available Background: Geothermal waters contain, among other components, soluble radon gas. Alpha radioactive radon is a health hazard to humans, especially when it gets into the respiratory tract. SPA facilities that use geothermal water can be a source of an increased radiation dose to people who stay there. Based on the available literature concerning radon concentrations, we assessed exposure to radon among people - workers and visitors of Spa centers that use geothermal waters. Material and Methods: Radon concentrations were analyzed in 17 geothermal centers: in Greece (3 centers, Iran (5, China (4 and India (5. Doses recived by people in the SPA were estimated using the formula that 1 hour exposure to 1 Bq/m3 of radon concentration and equilibrium factor F = 0.4 corresponds to an effective dose of 3.2 nSv. Results: We have found that radon levels in SPAs are from a few to several times higher than those in confined spaces, where geothermal waters are not used (e.g., residential buildings. In 82% of the analyzed SPAs, workers may receive doses above 1 mSv/year. According to the relevant Polish regulations, people receiving doses higher than 1 mSv/year are included in category B of radiation exposure and require regular dosimetric monitoring. Doses received by SPA visitors are much lower because the time of their exposure to radon released from geothermal water is rather short. Conclusions: The analysis of radon concentration in SPA facilities shows that the radiological protection of people working with geothermal waters plays an important role. It seems reasonable to include SPA workers staying close to geotermal waters into a dosimetric monitoring program. Med Pr 2013;64(2:193–198

  18. Molecular epidemiology of Staphylococcus aureus bacteremia in a single large Minnesota medical center in 2015 as assessed using MLST, core genome MLST and spa typing.

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    Kyung-Hwa Park

    Full Text Available Staphylococcus aureus is a leading cause of bacteremia in hospitalized patients. Whether or not S. aureus bacteremia (SAB is associated with clonality, implicating potential nosocomial transmission, has not, however, been investigated. Herein, we examined the epidemiology of SAB using whole genome sequencing (WGS. 152 SAB isolates collected over the course of 2015 at a single large Minnesota medical center were studied. Staphylococcus protein A (spa typing was performed by PCR/Sanger sequencing; multilocus sequence typing (MLST and core genome MLST (cgMLST were determined by WGS. Forty-eight isolates (32% were methicillin-resistant S. aureus (MRSA. The isolates encompassed 66 spa types, clustered into 11 spa clonal complexes (CCs and 10 singleton types. 88% of 48 MRSA isolates belonged to spa CC-002 or -008. Methicillin-susceptible S. aureus (MSSA isolates were more genotypically diverse, with 61% distributed across four spa CCs (CC-002, CC-012, CC-008 and CC-084. By MLST, there was 31 sequence types (STs, including 18 divided into 6 CCs and 13 singleton STs. Amongst MSSA isolates, the common MLST clones were CC5 (23%, CC30 (19%, CC8 (15% and CC15 (11%. Common MRSA clones were CC5 (67% and CC8 (25%; there were no MRSA isolates in CC45 or CC30. By cgMLST analysis, there were 9 allelic differences between two isolates, with the remaining 150 isolates differing from each other by over 40 alleles. The two isolates were retroactively epidemiologically linked by medical record review. Overall, cgMLST analysis resulted in higher resolution epidemiological typing than did multilocus sequence or spa typing.

  19. Numerical computation of central crack growth in an active particle of electrodes influenced by multiple factors

    Science.gov (United States)

    Zhang, Yuwei; Guo, Zhansheng

    2018-03-01

    Mechanical degradation, especially fractures in active particles in an electrode, is a major reason why the capacity of lithium-ion batteries fades. This paper proposes a model that couples Li-ion diffusion, stress evolution, and damage mechanics to simulate the growth of central cracks in cathode particles (LiMn2O4) by an extended finite element method by considering the influence of multiple factors. The simulation shows that particles are likely to crack at a high discharge rate, when the particle radius is large, or when the initial central crack is longer. It also shows that the maximum principal tensile stress decreases and cracking becomes more difficult when the influence of crack surface diffusion is considered. The fracturing process occurs according to the following stages: no crack growth, stable crack growth, and unstable crack growth. Changing the charge/discharge strategy before unstable crack growth sets in is beneficial to prevent further capacity fading during electrochemical cycling.

  20. Energy consumption during the building life cycle – influence of investment activities and operations

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    Vytlačil Dalibor

    2018-01-01

    Full Text Available The paper describes the dynamic model of maintenance and investments of a building structure and HVAC systems. The aim of the research is finding the time dependent curve for energy consumption and also the cash flow that depends on the investments to energy saving arrangements and operations. The solution is based on the system dynamics method. The method makes possible to interconnect technical and economic parts of the problem. The main parameter in the model is the energy consumption in the building per floor square meter and year. This parameter is influenced by a deterioration of the building structure and the components of the active elements. The investments realized with the aim to decrease the energy consumption is another influence. The example of the computer simulation of the building parameters during the life cycle is presented in the paper.