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Sample records for activation products mesures

  1. Absolute measurement of {beta} activities and application to the determination of neutronic densities; Mesure absolue d'activites {beta} et application a la determination des densites neutronique

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, R. [Commissariat a l' Energie Atomique, Lab. du Fort de Chatillon, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1951-01-15

    M. Berthelot, to my entrance to the ''Commissariat a l 'Energie Atomique'', proposed me to study the absolute measurement of neutron densities. Very quickly the problem of the absolute activity of {beta} sources became the central object of this work. In a first part, we will develop the methods of absolute determination for {beta} activities. The use of a 4{pi} counter permits to get the absolute activity of all beta radioactive source, susceptible to be put as thin leaf and of period superior than some minutes. The method is independent of the spectra of the measured radioelement. we will describe in the second part some applications which use neutron densities measurement, neutron sources intensities and ratio of cross sections of capture of thermal neutrons. (M.B.) [French] M. Berthelot, a mon entree au ''Commissariat a l 'Energie Atomique'', m'a propose d'etudier la mesure absolue des densites neutroniques. Tres rapidement le probleme de l'activite absolue des sources beta est devenu l'objet central de ce travail. Dans une premiere partie, on abordera les methodes de determination absolue des activites beta. L'utilisation d'un compteur 4{pi} permet d 'obtenir l'activite absolue de toute source radioactive beta, susceptible d'etre mise sous forme de feuille mince et de periode superieure a quelques minutes. La methode est independante du spectre du radioelement mesure. On decrira dans la seconde partie quelques applications a des mesures de densites neutroniques, d'intensites de sources de neutrons et de rapport de sections efficaces de capture de neutrons thermiques. (M.B.)

  2. Integral measurements of neutron production in spallation targets; Mesure integrale de la production de neutrons dans des cibles de spallation

    Energy Technology Data Exchange (ETDEWEB)

    Frehaut, J.; Deneuville, D.; Ledoux, X.; Lochard, J.P.; Longuet, J.L.; Petibon, E.; Alrick, K.; Bownan, D.; Cverna, F.; King, N.S.P.; Morgan, G.L. [Los Alamos National Lab., NM (United States); Greene, G.; Hanson, A.; Snead, L. [Brookhaven National Lab., Upton, NY (United States); Thompson, R. [Bechtel Nevada Corp., Las Vegas, NV (United States); Ward, T

    1998-12-31

    Measurements of neutron production for thick iron, tungsten and lead targets of different diameter prototypic for spallation systems have been made at SATURNE in an incident proton energy range from 400 MeV to 2 GeV. TIERCE code system calculations are in good agreement with experiment for iron and large diameter tungsten and lead targets. They overestimate the measured neutron production for tungsten and lead targets for diameter {<=}20 cm. (author) 10 refs.

  3. La mesure du danger

    CERN Document Server

    Manceron, Vanessa; Revet, Sandrine

    2014-01-01

    La mesure du danger permet d’explorer des dangers de nature aussi diverse que la délinquance, la pollution, l’écueil maritime, la maladie ou l’attaque sorcellaire, l’extinction d’espèces animales ou végétales, voire de la Planète tout entière. Au croisement de la sociologie, de l’anthropologie et de l’histoire, les différents articles analysent les pratiques concrètes de mesure pour tenter de comprendre ce qui se produit au cours de l’opération d’évaluation du danger sans préjuger de la nature de celui-ci. L’anthropologie a contribué à la réflexion sur l’infortune en s’intéressant aux temporalités de l’après : maladies, catastrophes, pandémies, etc. et en cherchant à rendre compte de l’expérience des victimes, de leur vie ordinaire bouleversée, de la recomposition du quotidien. Elle s’intéresse aussi aux autres types de mesures, les savoirs incorporés, qui reposent sur l’odorat, la vue ou le toucher et ceux qui ressortent d’une épistémologie « non ...

  4. Instruments de mesure en acoustique

    DEFF Research Database (Denmark)

    Tarnov, Viggo; Jacobsen, Finn

    2008-01-01

    La mesure en acoustique fait appel à des instruments qui mesurent, d'une part la pression, d'autre part l'intensité du signal. Ce dossier présentera, notamment, deux appareils spécialisés : les sonomètres et les microphones. Il abordera l'ensemble des informations majeures à connaître sur les...

  5. High-sensitivity gamma spectroscopy for extended sources. Application to activity measurements on the human body, on glass, and on soil; Spectrographie gamma a grande sensibilite pour sources etendues. Application a la mesure de l'activite du corps humain, du verre et du sol

    Energy Technology Data Exchange (ETDEWEB)

    Jouve, B

    1962-07-01

    The measurement and location by gamma spectroscopy of human body internal contaminations at maximum permissible levels, and, in certain cases, at lower activities such as that due to {sup 40}K was investigated. The characteristics of the high-sensitivity apparatus used are given, and several assemblies using large-volume NaI(Tl) scintillators are described. The relatively light shielding required for natural radioactivity permitted construction of mobile assembly. Conditions of use are described, and the results are given. All gamma emitting elements were measured in 15 min at levels lower than the tolerance dose. Gamma spectroscopy was also used to determine fission products in the earth and to study radioactive elements in the presence of other emitters. (author) [French] La spectrographie gamma du corps humain permet la mesure et la localisation des contaminations internes au niveau des doses de tolerance et, dans certains cas, celle d'activites plus faibles comme la radioactivite naturelle due principalement au potassium 40. Les caracteristiques des appareils a grande sensibilite permettant ces mesures sont exposees et on decrit plusieurs realisations originales utilisant un scintillateur NaI(Tl) de grand volume. L'epaisseur du blindage a ete limitee a 5 cm de plomb, ainsi, pour une protection suffisante contre les rayonnements ambiants, les appareils sont relativement legers et l'une des realisations a pu etre installee dans un laboratoire mobile. Les conditions d'utilisation (mouvement propre, etalonnage) et les resultats obtenus sont donnes; tous les radioelements emetteurs gamma sont mesurables en 15 minutes a un niveau inferieur a la dose de tolerance. On presente enfin des applications a la spectrographie gamma d'echantillons volumineux (poudres ou liquides) et de tres faible activite: elles interessent des domaines tres varies comme, par exemple, la geophysique (etude des retombees radioactives) ou l'industrie chimique

  6. Development of magnetic calorimeters for absolute activity measurement; Developpement de calorimetres magnetiques pour la mesure absolue d'activite

    Energy Technology Data Exchange (ETDEWEB)

    Loidl, M.; Leblanc, E.; Rodrigues, M.; Qasimi, A.; Bouchard, J.; Censier, B.; Branger, T.; Lacour, D. [CEA Saclay, LNE-LNHB, Lab. National Henri Becquerel, LIST, 91 - Gif-sur-Yvette (France)

    2009-07-01

    We have developed a prototype magnetic calorimeter, operated at very low temperature, for absolute activity measurement of low energy emitting radionuclides. A weighed source of {sup 55}Fe has been enclosed inside the detector absorber assuring a high detection efficiency. The result of a preliminary activity measurement carried out with this prototype is compatible with a measurement by liquid scintillation counting. Apart from the high detection efficiency, this approach is particularly interesting since it introduces a new method into a field where only few measuring techniques are available. (authors)

  7. Transmutation program: preliminary measurements about the production of spallation neutrons; Programme transmutation: resultats des mesures elementaires sur la production de neutrons de spallation

    Energy Technology Data Exchange (ETDEWEB)

    Leray, S. [Laboratoire National Saturne - Centre d`Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France); Beau, M. [CEA Centre d`Etudes de Bruyeres-le-Chatel, 91 (France); Boudard, A. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. d`Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l`Instrumentation Associee] [and others

    1996-12-31

    The programme to measure the double differential cross-sections for the production of neutrons induced by protons and deuterons on various targets is presented. Two different experimental techniques are used for these measurements: for the low energy part of the neutron spectrum, time-of-flight is employed between the incident tagged proton and a NE213-scintillator detecting the neutron. At high energies, the neutron energy spectrum is obtained through the detection of recoil protons in a magnetic spectrometer, after scattering in a liquid hydrogen convector. The first results are discussed. The Phase 2 in which the experimental set-up will be modified to allow for the measurement of complete angular distributions and the study of neutron energy spectra from thick targets is also presented. (authors) 13 refs.

  8. Mesure de la production de J/psi en collisions p-Pb au LHC avec le spectromètre à muons d'ALICE

    CERN Document Server

    Lakomov, Igor

    Hard probes represent one of the hottest topics of the modern high energy physics. The production mechanism of quarkonia (mesons composed of a charm or beauty quark and its antiquark) in hadronic collisions is of particular interest. The suppression of J/psi and other charmonium states was predicted as one of the first signatures of the Quark Gluon Plasma (QGP) formation and was seen at RHIC and SPS. It was also studied at the LHC in Pb-Pb collisions. However, other effects can affect the charmonium production in Pb-Pb collisions without the presence of the QGP. These effects are inherent to the use of nuclei and are called “Cold Nuclear Matter” (CNM) effects. They can be studied in p-Pb collisions. This thesis is dedicated to the studies of J/psi production in p-Pb collisions at the LHC at a center of mass energy of 5.02 TeV per nucleon pair. J/psi production is studied as a function of transverse momentum, rapidity and event activity. These results represent a significant step to better understanding of...

  9. MESURE DE LA PERFORMANCE GLOBALE DES ENTREPRISES

    OpenAIRE

    Renaud, Angèle; Berland, Nicolas

    2007-01-01

    International audience; L'engagement des entreprises dans le développement durable consiste à conjuguer performance et responsabilité. La performance financière ne suffit plus à apprécier la performance d'une entreprise. Dès lors, les entreprises doivent mesurer leurs progrès à partir d'une performance plus globale incluant, en dehors de la dimension économique, des dimensions sociale et environnementale. A présent, comment mesurer cette performance globale ? Existe-il des outils de mesure gl...

  10. Production Systems. Laboratory Activities.

    Science.gov (United States)

    Gallaway, Ann, Ed.

    This production systems guide provides teachers with learning activities for secondary students. Introductory materials include an instructional planning outline and worksheet, an outline of essential elements, domains and objectives, a course description, and a content outline. The guide contains 30 modules on the following topics: production…

  11. Mesures de production de la particule neutre et étrange $K^{0}_{S}$ dans l'expérience HARP

    CERN Document Server

    Prior, Gersende; Blondel, A

    2005-01-01

    The hadron production experiment HARP (PS214) carried out a programme of measurements of secondary hadrons at the European Organization for Nuclear Research (CERN) proton synchrotron (PS) during the years 2001 and 2002. It serves several purposes. On one side there is a need to acquire knowledge of pion yields for an optimal design of the proposed neutrino factories and superbeams. On the other one, we have to improve substantially the calculation of the atmospheric neutrino flux, used by past and forthcoming experiments designed to measure neutrino oscillations. HARP data will also provide a general input for simulation of particles traversing matter, as well as neutrino beam predictions for the K2K and MiniBooNE experiments. The subject of this thesis is to provide strange particle production, K0S, measurements, from HARP data. This study is of interest because, for neutrino beams, the charged kaon contamination induces an electron-neutrino type background in the muon-neutrino beam. The knowledge of such a ...

  12. Performance du spectrometre a muons d’ALICE. Production et mesure des bosons faibles dans des collisions d’ions lourds aupres du LHC

    CERN Document Server

    Conesa Del Valle, Zaida; Moreno, F Fernandez

    2007-01-01

    Nucleus-nucleus collisions are the unique tool available to investigate the QCD matter phase diagram in the laboratory. A lot of work has been devoted to explore it in different domains in the last 3 decades, and the forthcoming LHC collider will contribute to such research increasing the collision center-of-mass energy by a factor 30 and the energy densities by a factor 1-10 with respect to the RHIC collider [C+04, A+06].Only a comprehensive analysis of a wide spectrum of experimental observables can help to fully characterize the prospected matter. In particular, valuable information is expected from charm and beauty production, the situation from SPS and RHIC charmonia data being puzzling [GdC07, Lei07, A+00a, Sco07], and the c¯c (b¯b) yields per central nucleon-nucleon collision being increased from 10 (0.1) to 110 (5) from RHIC to LHC [C+04, MG07]. Whether quarkonia will thermalize, will develop collective motion, will be further suppressed or regenerated are still open questions that LHC data might re...

  13. Mesure de la section efficace de production des hadrons lourds avec le spectromètre à muons d'ALICE au LHC

    CERN Document Server

    Manceau, Loïc

    Lattice quantum chromodynamics calculations predict a transition from the phase of hadronic matter to quark and gluon plasma for a temperature T ∼ 173 MeV and a vanishing baryonic potential. Ultra-relativistic heavy ion collisions allow to highlight this phase transition. Heavy flavours can be used to probe the first instants of the collisions where the temperature is the highest. The LHC will provide proton-proton and lead-lead collisions at unprecedented large energy (√s = 14 TeV and √sNN = 5.5 TeV respectively). The ALICE detector is dedicated to heavy ion collisions but it can also measure proton-proton collisions. The detector includes a muon spectrometer. The spectrometer has been disigned to measure heavy flavours. This PhD thesis presents the performance of the spectrometer to measure beauty hadrons (B) and charmed hadrons (D) inclusive production cross-section in proton-proton collisions. The first step of the measurement consists in extracting heavy hadron decayed muon distributions. The next ...

  14. MESUR: metrics from scholarly usage of resources

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    The MESUR project is constructing a large-scale semantic model of the scholarly community that seamlessly integrates a wide range of bibliographic, citation and usage data. Functioning as a reference data set, this model is analyzed to characterize the intricate networks of typed relationships that exist in the scholarly community. The resulting ...

  15. MESUR metrics from scholarly usage of resources

    CERN Document Server

    CERN. Geneva; Van de Sompel, Herbert

    2007-01-01

    Usage data is increasingly regarded as a valuable resource in the assessment of scholarly communication items. However, the development of quantitative, usage-based indicators of scholarly impact is still in its infancy. The Digital Library Research & Prototyping Team at the Los Alamos National Laboratory's Research library has therefore started a program to expand the set of usage-based tools for the assessment of scholarly communication items. The two-year MESUR project, funded by the Andrew W. Mellon Foundation, aims to define and validate a range of usage-based impact metrics, and issue guidelines with regards to their characteristics and proper application. The MESUR project is constructing a large-scale semantic model of the scholarly community that seamlessly integrates a wide range of bibliographic, citation and usage data. Functioning as a reference data set, this model is analyzed to characterize the intricate networks of typed relationships that exist in the scholarly community. The resulting c...

  16. Contribution of the active control to the measurement of fluid-elastic coupling strengths; Apport du controle actif pour la mesure des forces de couplage fluide-elastique

    Energy Technology Data Exchange (ETDEWEB)

    Legendre, S

    1999-06-30

    A precise dimensioning of the tubes inside a steam generator requires a better knowledge of the fluid-elastic coupling phenomena. The direct method for the determination of fluid-elastic coupling coefficients allows to explore only a reduced range of flow velocities and is unsuitable for the low velocities and for velocities close to the critical instability velocity. The active damping control method has been validated both with air and water and offers the possibility to extend the range of flow velocities using an artificial supply of damping: 50% of increase in single-phase flow conditions with measurements performed beyond the critical instability velocity, a doubling of the explored range of velocities in two-phase flow conditions. For a 25% two-phase flow, a stabilization of the damping of the coupled fluid-structure system is observed beyond the critical instability velocity. Finally, the calculation of fluid-elastic dimensionless coefficients has permitted to show the influence of the reduced velocity on the fluid-elastic coupling in two-phase flow conditions. (J.S.)

  17. Commercial Product Activation Using RFID

    Science.gov (United States)

    Jedrey, Thomas

    2008-01-01

    Radio-frequency identification (RFID) would be used for commercial product activation, according to a proposal. What is new here is the concept of combining RFID with activation - more specifically, using RFID for activating commercial products (principally, electronic ones) and for performing such ancillary functions as tracking individual product units on production lines, tracking shipments, and updating inventories. According to the proposal, an RFID chip would be embedded in each product. The information encoded in the chip would include a unique number for identifying the product. An RFID reader at the point of sale would record the number of the product and would write digital information to the RFID chip for either immediate activation of the product or for later interrogation and processing. To be practical, an RFID product-activation system should satisfy a number of key requirements: the system should be designed to be integrable into the inventory-tracking and the data-processing and -communication infrastructures of businesses along the entire supply chain from manufacture to retail; the system should be resistant to sophisticated hacking; activation codes should be made sufficiently complexity to minimize the probability of activating stolen products; RFID activation equipment at points of sale must be capable to two-way RF communication for the purposes of reading information from, and writing information to, embedded RFID chips; the equipment at points of sale should be easily operable by sales clerks with little or no training; the point-of-sale equipment should verify activation and provide visible and/or audible signals indicating verification or lack thereof; and, the system should be able to handle millions of products per year with minimal human intervention, among other requirements.

  18. Minimizing activated carbons production cost

    International Nuclear Information System (INIS)

    Stavropoulos, G.G.; Zabaniotou, A.A.

    2009-01-01

    A detailed economic evaluation of activated carbons production process from various raw materials is undertaken using the conventional economic indices (ROI, POT, and NPV). The fundamental factors that affect production cost were taken into account. It is concluded that for an attractive investment in activated carbons production one should select the raw material with the highest product yield, adopt a chemical activation production scheme and should base product price on product-surface area (or more generally on product adsorption capacity for the adsorbate in consideration). A raw material that well meets the above-mentioned criteria is petroleum coke but others are also promising (charcoals, and carbon black). Production cost then can be optimized by determining its minimum value of cost that results from the intercept between the curves of plant capacity and raw material cost - if any. Taking into account the complexity of such a techno-economic analysis, a useful suggestion could be to start the evaluations from a plant capacity corresponding to the break-even point, i. e. the capacity at which income equals production cost. (author)

  19. Advanced Aerodynamic Measurement Technology (Technologies avancees de mesure aerodynamique)

    Science.gov (United States)

    1998-05-01

    Norwegian Defence Research Establ. P.O. Box 25 N-2007 Kjeller - NORWAY Dr. Roque CORRAL Departemento de Mecanica de Fluidos Industria de ...CONFERENCE PROCEEDINGS 601 Advanced Aerodynamic Measurement Technology (Technologies avancees de mesure aerodynamique) Papers presented and discussions...CONFERENCE PROCEEDINGS 601 Advanced Aerodynamic Measurement Technology (Technologies avancees de mesure aerodynamique) Apprcvrc /oi ■■■■- M

  20. Activation Product Inverse Calculations with NDI

    Energy Technology Data Exchange (ETDEWEB)

    Gray, Mark Girard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-27

    NDI based forward calculations of activation product concentrations can be systematically used to infer structural element concentrations from measured activation product concentrations with an iterative algorithm. The algorithm converges exactly for the basic production-depletion chain with explicit activation product production and approximately, in the least-squares sense, for the full production-depletion chain with explicit activation product production and nosub production-depletion chain. The algorithm is suitable for automation.

  1. Mesure de la section efficace de production des quarks beaux et charmés à partir de leur désintegration semileptonique en électrons avec l'experience ATLAS dans les collisions protons-protons a sqrt(s) = 7 TeV au LHC.

    CERN Document Server

    Bordoni, Stefania

    Le thème central de la thèse est la mesure de la section efficace de production des électrons venant de la désintégration des quarks lourds (b et c) avec l'expérience ATLAS dans les collisions proton-proton à sqrt(s)=7 TeV au LHC. La calibration du calorimètre électromagnétique et la reconstruction des électrons jouent un rôle cardinal dans l'analyse développée dans cette thèse. Ces thématiques sont traitées dans la première partie du manuscrit. L'étude des systématiques liées à la variation des constantes de calibration paramètrant la chaîne de lecture du calorimètre et qui affectent la reconstruction de l'énergie des cellules est presentée. La description des procédures de reconstruction des événements dans le détecteur ATLAS est ensuite traitée. Les cas de mauvaise reconstruction sont abordés et une étude de l'estimation du taux des faux leptons dans des événements multi-jets est présentée. La deuxième partie de la thèse est dédiée à la mesure de la section ef...

  2. Control of radioactive wastes and coupling of neutron/gamma measurements: use of radiative capture for the correction of matrix effects that penalize the fissile mass measurement by active neutron interrogation; Controle des dechets radioactifs et couplage de mesures neutron/gamma: exploitation de la capture radiative pour corriger les effets de matrice penalisant la mesure de la masse fissile par interrogation neutronique active

    Energy Technology Data Exchange (ETDEWEB)

    Loche, F

    2006-10-15

    In the framework of radioactive waste drums control, difficulties arise in the nondestructive measurement of fissile mass ({sup 235}U, {sup 239}Pu..) by Active Neutron Interrogation (ANI), when dealing with matrices containing materials (Cl, H...) influencing the neutron flux. The idea is to use the neutron capture reaction (n,{gamma}) to determine the matrix composition to adjust the ANI calibration coefficient value. This study, dealing with 118 litres, homogeneous drums of density less than 0,4 and composed of chlorinated and/or hydrogenated materials, leads to build abacus linking the {gamma} ray peak areas to the ANI calibration coefficient. Validation assays of these abacus show a very good agreement between the corrected and true fissile masses for hydrogenated matrices (max. relative standard deviation: 23 %) and quite good for chlorinated and hydrogenated matrices (58 %). The developed correction method improves the measured values. It may be extended to 0,45 density, heterogeneous drums. (author)

  3. Measurement of gluon polarization through spin asymmetry in the production of charmed mesons; Mesure de la polarisation des gluons par l'asymetrie de spin dans la production de mesons charmes

    Energy Technology Data Exchange (ETDEWEB)

    Panebianco, St

    2005-09-15

    The main aim of the COMPASS experiment is the measurement of the gluon polarization in the nucleon, which can be accessed by the spin asymmetry in the scattering of a polarized muon beam on a polarized nucleon target. The process sensitive to the gluon polarization is the photon-gluon fusion, which can be tagged in the cleanest way by looking at the production of D{sup 0} mesons. At COMPASS, D{sup 0} mesons are reconstructed from the invariant mass of their decay products. However, it is a rare process, dominated by a large combinatorial background. This thesis presents some studies devoted to the improvement of the charmed mesons reconstruction. The measurement of the efficiency and the space resolution of the 3 drift chamber stations of the COMPASS spectrometer is a necessary step in understanding the performances of the reconstruction of particle trajectories. The hadron identification, which is fundamental in the reconstruction of charmed meson decay, is performed by a RICH detector. A statistical treatment of signal and background, together with an upgrade project to replace the present front-end electronics, have been developed in order to improve the particle identification performances. The second part of this work concerns the spin asymmetry measurement, which requires the application of event selection criteria in order to minimize the noise over signal ratio in the D{sup 0} invariant mass, and the development of event-weighting methods to reduce the statistical error. This work presents a preliminary result, based on 2002-2004 statistics, which is the {delta}G/G measurement from open charm production. Although the error bars are large, the measured gluon polarization is compatible with zero. Given the present accuracy, this result is compatible with the existing direct measurements from other channels. However, it does not allow to distinguish between different theoretical models. (author)

  4. Action de divers diluants sur les produits pétroliers lourds : mesure, interprétation et prévision de la floculation des asphaltènes Action of Different Thinners on Heavy Petroleum Products: Measuring, Interpreting and Forecasting Asphaltene Flocculation

    Directory of Open Access Journals (Sweden)

    Hotier G.

    2006-11-01

    Full Text Available La mesure de la teneur normalisée en asphaltènes ne fournit pas de renseignements sur le moment d'apparition de la précipitation ni sur sa cinétique. Ces phénomènes ont une importance pratique indéniable et leur étude fait l'objet de ce travail. Dans cet article, on définit le seuil de floculation et l'on présente une méthode originale de mesure de ce dernier. On introduit ensuite la notion de potentiel de précipitation et l'on démontre ses propriétés d'additivité. Cette notion permet de prévoir, à partir d'un petit nombre d'essais, si la dilution d'un produit pétrolier lourd par une certaine quantité d'un diluant pur ou d'un mélange de diluants provoque ou non la floculation des asphaltènes. De plus, les potentiels de précipitation permettent de classer les différents diluants en fonction de leur aptitude à faire floculer ou à solubiliser les asphaltènes. A measurement of the standardized asphaltene content does not provide any information neither on the incipient flocculation moment nor on the precipitation kinetics. These phenomena are of undeniable practical importance, and they are examined in this article. Flocculation threshold is defined, and an original method of measuring it is described. Then the notion of precipitation potential is taken up, and its additivity properties are brought out. With only a small number of tests, this notion can be used to forecast whether the dilution of a heavy petroleum product by a given amount of pure thinner or by a mixture of thinners causes asphaltene flocculation or not. Furthermore, precipitation potentials can be used to classify different thinners as a function of their capacity to flocculate or solubilize asphaltenes.

  5. Developpement de mesures non destructives, par ondes ultrasonores, d'epaisseurs de fronts de solidification dans les reacteurs metallurgiques

    Science.gov (United States)

    Floquet, Jimmy

    Dans les cuves d'electrolyse d'aluminium, le milieu de reaction tres corrosif attaque les parois de la cuve, ce qui diminue leur duree de vie et augmente les couts de production. Le talus, qui se forme sous l'effet des pertes de chaleur qui maintiennent un equilibre thermique dans la cuve, sert de protection naturelle a la cuve. Son epaisseur doit etre controlee pour maximiser cet effet. Advenant la resorption non voulue de ce talus, les degats generes peuvent s'evaluer a plusieurs centaines de milliers de dollars par cuve. Aussi, l'objectif est de developper une mesure ultrasonore de l'epaisseur du talus, car elle serait non intrusive et non destructive. La precision attendue est de l'ordre du centimetre pour des mesures d'epaisseurs comprenant 2 materiaux, allant de 5 a 20 cm. Cette precision est le facteur cle permettant aux industriels de controler l'epaisseur du talus de maniere efficace (maximiser la protection des parois tout en maximisant l'efficacite energetique du procede), par l'ajout d'un flux thermique. Cependant, l'efficacite d'une mesure ultrasonore dans cet environnement hostile reste a demontrer. Les travaux preliminaires ont permis de selectionner un transducteur ultrasonore a contact ayant la capacite a resister aux conditions de mesure (hautes temperatures, materiaux non caracterises...). Differentes mesures a froid (traite par analyse temps-frequence) ont permis d'evaluer la vitesse de propagation des ondes dans le materiau de la cuve en graphite et de la cryolite, demontrant la possibilite d'extraire l'information pertinente d'epaisseur du talus in fine. Fort de cette phase de caracterisation des materiaux sur la reponse acoustique des materiaux, les travaux a venir ont ete realises sur un modele reduit de la cuve. Le montage experimental, un four evoluant a 1050 °C, instrumente d'une multitude de capteurs thermique, permettra une comparaison de la mesure intrusive LVDT a celle du transducteur, dans des conditions proches de la mesure

  6. Contribution to the precise measurement of the activity of non-point sources by the use of the well-type ionization chamber; Contribution a la mesure precise de l'activite de sources non ponctuelles au moyen de la chambre d'ionisation a puits

    Energy Technology Data Exchange (ETDEWEB)

    Dalmazzone, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-10-01

    The well-type ionisation chamber is commonly used to measure the activity of solid, liquid or gaseous {beta}, {gamma} and {beta}-{gamma} sources (the first by making use of Bremsstrahlung) over a wide activity range (from a few {mu}Ci to several Ci). The volume of these sources can be appreciable owing to the existence of large 'zones of equal sensitivity' verified by means of a Ra point source. However the response of the chamber is closely dependent on the geometry of the source, in particular its volume, for weakly penetrating radiations such as ({beta}'S, Bremsstrahlung and soft {gamma}'S (E{sub {gamma}} below 100 keV), because of the attenuating power of the materials making up the source, the measuring apparatus and the comparatively high ionising power of low-energy X and {gamma} rays (predominant photoelectric effect). As a result the concept of zones of equal sensitivity depends not only on the geometry of the chamber but also on that of the source and on the energy of the photons (X or {gamma}) emitted by it. We have thus made a systematic study of the importance of the source geometry in activity measurements with the well- type chamber, for 18 {beta}, {gamma} or {beta}-{gamma} emitting radionuclides. (author) [French] La chambre d'ionisation a puits est couramment utilisee pour mesurer l'activite de sources {beta} (par l'intermediaire des X de freinage), {gamma} et {beta} - {gamma} solides, liquides ou gazeuses dans un large domaine d'activite (de quelques {mu}Ci a quelques Ci). Ces sources peuvent avoir des volumes appreciables grace a l'existence de 'zones d'egales sensibilites' importantes verifiees a l'aide d'une source ponctuelle de Ra. Cependant la reponse de la chambre depend etroitement de la geometrie de la source, en particulier, de son volume, pour les rayonnements peu penetrants tels que {beta}, X de freinage et {gamma} mous (E{sub {gamma}} inferieure a une centaine de ke

  7. Improvement of personalized Monte Carlo-aided direct internal contamination monitoring: optimization of calculation times and measurement methodology for the establishment of activity distribution; Amelioration des mesures anthroporadiametriques personnalisees assistees par calcul Monte Carlo: optimisation des temps de calculs et methodologie de mesure pour l'etablissement de la repartition d'activite

    Energy Technology Data Exchange (ETDEWEB)

    Farah, Jad

    2011-10-06

    To optimize the monitoring of female workers using in vivo spectrometry measurements, it is necessary to correct the typical calibration coefficients obtained with the Livermore male physical phantom. To do so, numerical calibrations based on the use of Monte Carlo simulations combined with anthropomorphic 3D phantoms were used. Such computational calibrations require on the one hand the development of representative female phantoms of different size and morphologies and on the other hand rapid and reliable Monte Carlo calculations. A library of female torso models was hence developed by fitting the weight of internal organs and breasts according to the body height and to relevant plastic surgery recommendations. This library was next used to realize a numerical calibration of the AREVA NC La Hague in vivo counting installation. Moreover, the morphology-induced counting efficiency variations with energy were put into equation and recommendations were given to correct the typical calibration coefficients for any monitored female worker as a function of body height and breast size. Meanwhile, variance reduction techniques and geometry simplification operations were considered to accelerate simulations. Furthermore, to determine the activity mapping in the case of complex contaminations, a method that combines Monte Carlo simulations with in vivo measurements was developed. This method consists of realizing several spectrometry measurements with different detector positioning. Next, the contribution of each contaminated organ to the count is assessed from Monte Carlo calculations. The in vivo measurements realized at LEDI, CIEMAT and KIT have demonstrated the effectiveness of the method and highlighted the valuable contribution of Monte Carlo simulations for a more detailed analysis of spectrometry measurements. Thus, a more precise estimate of the activity distribution is given in the case of an internal contamination. (author)

  8. Development of a photonuclear activation file and measurement of delayed neutron spectra; Creation d'une bibliotheque d'activation photonucleaire et mesures de spectres d'emission de neutrons retardes

    Energy Technology Data Exchange (ETDEWEB)

    Giacri-Mauborgne, M.L

    2005-11-15

    This thesis work consists in two parts. The first part is the description of the creation of a photonuclear activation file which will be used to calculated photonuclear activation. To build this file we have used different data sources: evaluations but also calculations done using several cross sections codes (HMS-ALICE, GNASH, ABLA). This file contains photonuclear activation cross sections for more than 600 nuclides and fission fragments distributions for 30 actinides at tree different Bremsstrahlung energies and the delay neutron spectrum associated. These spectra are not in good agreement with experimental data. That is why we decided to launch measurement of delayed neutrons spectra from photofission. The second part of this thesis consists in demonstrating the possibility to do such measurements at the ELSA accelerator facility. To that purpose, we have developed the detection, the acquisition system and the analysis method of such spectra. These were tested for the measurement of the delayed neutron spectrum of uranium-238 after irradiation in a 2 MeV neutron flux. Finally, we have measured the delayed neutron spectrum of uranium-238 after irradiation in a 15 MeV Bremsstrahlung flux. We compare our results with experimental data. The experiment has allowed us to improve the value of {nu}{sub p}-bar with an absolute uncertainty below 7%, we propose {nu}{sub p}-bar = (3.03 {+-} 0.02) n/100 fissions, and to correct the Nikotin's parameters for the six group representation. Particularly, we have improved the data concerning the sixth group by taking into account results from different irradiation times.

  9. Les mesures de métrologie pour le CLIC

    CERN Document Server

    Cherif, A

    2008-01-01

    Le projet CLIC est en tout point un défi technique majeur ; c?est le cas également pour la mesure dimensionnelle. Quels sont les équipements et les méthodes qui permettent de caractériser les pièces avec une incertitude de mesure aussi réduite que possible, vu les tolérances micrométriques imposées ? Afin de répondre à cette question, une veille technologique a été maintenue sur une longue période. Les acteurs relevants ont été contactés pour bénéficier d?une ouverture sur les dernières avancées dans le domaine. Différentes techniques ont été étudiées et comparées telles que la digitalisation, la tomographie X, la mesure tridimensionnelle. L'assemblage de haute précision des composants est aussi primordial. Sa mise en ?uvre sous un microscope optique ou à l'aide d'une machine tridimensionnelle est en cours d?étude. L'exposé traitera aussi de la mesure de rugosité, un domaine où nous disposons de moyens adaptés aux exigences spécifiques du projet.

  10. Mesure de la section efficace différentielle de production du boson Z se désintégrant en paires électron-positon, dans l'expérience ATLAS

    CERN Document Server

    Doan, Thi Kieu Oanh; Theodore, T

    There are several reasons to study the $Z$ and $W$ bosons at LHC. The understanding of weak vector boson production tests the Standard Model predictions and is necessary to maximize the sensitivity to new physics at hadron colliders. Moreover, the $W$ and $Z$ boson productions play an important role in the calibration of the ATLAS (A Toroidal LHC ApparatuS) detector. The focus of my thesis work is on the study of a new variable which addresses the same physics issues as the $Z$ transverse momentum ($p^Z_T$). The relatively large cross section at LHC of the $Z$ production decaying into lepton pairs and its very low background enable a precise measurement of $p^Z_T$ which gives a very sensitive way of studying dynamical effects of the strong interaction, complementary to measurements of the associated production of the bosons with jets. At large $p^Z_T$ (greater than approximately 30 GeV), the radiation of a single parton with large transverse momentum dominates the cross section, and fixed-order perturbativ...

  11. Mesure de la section efficace de production de paires de quarks top dans le canal μ + jets + τ + b-jet(s) + Energie transverse manquante auprès de l'expérience DØ du Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Jammes, Jerome [Blaise Pascal Univ., Aubiere (France)

    2011-09-09

    The purpose of high energy physics is to improve our knowledge about the fundamental structure of matter, in particular about particles that constitute the world. One of these is the top quark, that was discovered in 1995 by the CDF and D0 collaborations at the Tevatron protons-antiprotons collider. One of the primary aim of the Tevatron has been then the fine study of the top quark properties, in particular the top-antitop production cross section. Different analysis have been performed in the leptons (μ,e,τ) + jets, dileptons, and all hadronic channels to determine accurately the values of these parameters, and thus to test the validity of the Standard Model. The main goal of this thesis is to verify one of the theoretical predictions of the Standard Model of particle physics, the top-antitop production cross section, at the Tevatron collider.

  12. Does Design Activity Stimulate Firm Productivity? (Japanese)

    OpenAIRE

    KAWAKAMI Atsushi; EDAMURA Kazuma

    2015-01-01

    This paper investigates the influence of firms' design activity to total factor productivity using firm-level data from the Basic Survey of Japanese Business Structure and Activities and the Survey on Research Activities of Private Corporations. We adopt two approaches for calculating design activity. First, we regard registered design as a design activity. Second, we calculate design investment from the Survey on Research Activities of Private Corporations and estimate the relation between d...

  13. Performance des jets et mesure de la section efficace de production de paires t tbar dans le canal tout hadronique auprès du détecteur ATLAS

    CERN Document Server

    Ghodbane, N

    In this report, we summarise our research program within the ATLAS collaboration between 2005-2012. We summarise our contribution to the integration of two of the Inner Detector sub-detectors, the SCT and the TRT. We describe also our contribution to the optimisation and tuning of the jet reconstruction in the harsh ATLAS environment. We compare the performances of these different algorithms. Finally, with the data collected at a centre of mass energy of 7 TeV, we extract the top-anti-top production cross section in the challenging all-hadronic decay channel.

  14. Mesure de la section efficace de production de paires de quarks top dans le canal lepton+tau+jets+MET dans l'experience D0 et interpretation en termes de boson de Higgs charge

    Energy Technology Data Exchange (ETDEWEB)

    Lacroix, Florent [Clermont-Ferrand U.

    2008-12-01

    The standard model of particle physics describes the matter as elementary particles interacting via strong and electroweak interactions. The top quark is the heaviest quark described by this model and has been discovered in 1995 by CDF and D collaborations in proton-antiproton collisions at the Tevatron. This thesis is devoted to the measurement of the top pair production cross-section via the strong interaction, in a final state composed of one lepton, one hadronic tau, two b-jets and missing transverse energy. This analysis uses the 1,2 fb

  15. Mesure de la section efficace de production de paires de photons isolés dans l'expérience ATLAS au LHC et étude des couplages à quatre photons

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00387311; Schoeffel, Laurent

    The LHC, which is the most powerful proton-proton collider in the world located at CERN (Switzerland), brings unprecedented opportunities to test our knowledge of the fundamental interactions at the TeV scale. In this work, two main projects have been achieved for this purpose. First, the production cross section measurement of at least two photons in the final state ($pp\\rightarrow\\gamma\\gamma+X$) is performed with data taken at a center-of-mass energy of 8 TeV by the ATLAS detector, which is one of the multipurpose detector installed around the LHC ring. Photons are interesting probes to test the theory of strong interactions (Quantum chromodynamics or QCD) since they couple significantly to quarks but do not hadronize and thus still allow to perform high resolution measurements. The measurement of their production rate at the LHC allows to test QCD in both the perturbative and the non-perturbative domain. It is also sensitive to the emission of soft particles in the initial-state, which is tricky to handle...

  16. Étude des performances du spectromètre à muons du détecteur Atlas au LHC, des cosmiques aux collisions. Mesure de la section efficace de production des dibosons WZ.

    CERN Document Server

    Le Menedeu, Eve

    2011-01-01

    ATLAS is one of the four experiments at the Large Hadron Collider (LHC), located at CERN, Geneva. As the LHC only delivered its first collisions in December 2009, at an energy of 7 TeV in the centre-of-mass, ATLAS recorded millions of cosmic events in 2008 and 2009 in order to better understand the detector. The first part of this PhD thesis deals with these cosmic events in order to estimate the muon spectrometer performances, particularly its efficiency and resolution. Next, using 7 TeV collisions, the efficiency is determined using a “Tag and Probe” method on Z events decaying into muons. In addition, the missing transverse energy is studied and a clear improvement of its resolution is achieved through a better treatment of the muons. Finally, muons, missing transverse energy, but also electrons, are used to estimate the production cross-section of WZ dibosons. Event selection, backgrounds estimation and systematics errors are provided. A computation of the WZ cross-section using 1.02 fb−1 of data an...

  17. Natural products and anti-inflammatory activity.

    Science.gov (United States)

    Yuan, Gaofeng; Wahlqvist, Mark L; He, Guoqing; Yang, Min; Li, Duo

    2006-01-01

    The aim of this review paper was to summarise some commonly available natural products and their anti-inflammatory activity. We have collected data from MEDLINE, Current Contents and scientific journals, which included 92 publications. There are numerous natural products detailed in this literature; however we have summarized a few of the most commonly available and potent ones. In this paper, the natural products with anti-inflammatory activity including curcumin, parthenolide, cucurbitacins, 1,8-cineole, pseudopterosins, lyprinol, bromelain, flavonoids, saponins, marine sponge natural products and Boswellia serrata gum resin were reviewed. Natural products play a significant role in human health in relation to the prevention and treatment of inflammatory conditions. Further studies are being conducted to investigate the mechanism of action, metabolism, safety and long term side effect of these natural products, as well as interactions between these natural products with food and drug components.

  18. Absolute measurement of {beta} emitters with a 4 {pi} counter; Mesure absolue des emetteurs {beta} au compteur 4 {pi}

    Energy Technology Data Exchange (ETDEWEB)

    Le Gallic, Y. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1959-06-15

    The object of this work is to investigate the conditions under which the activity of {beta}-emitting radionuclides may be measured with a maximum of precision, and as a result to study the relevant corrections. The various problems relating to activity measurements with a 4 {pi} counter have been examined successively: - comparison of 4 {pi}, GM and proportional counters; - study of the preparation of sources; - corrections on the counting of sources; - self-absorption; - correction for absorption. The precision obtained on these measurements varies from 1.2 to 3 per cent, with the result that the 4 {pi} counter can be considered a very satisfactory calibration instrument. (author) [French] Le but de ce travail est de rechercher les conditions permettant d'obtenir avec le maximum de precision, la mesure de l'activite des radionuclides se desintegrant par emission et par consequent d'etudier les corrections qui s'y rapportent. Nous avons examine successivement les differents problemes se rapportant aux mesures d'activite au compteur 4 {pi}: - Comparaison des compteurs 4 {pi}, GM et proportionnel; - etude de la preparation des sources; - corrections sur la numeration des sources; - auto-absorption; - correction d'absorption. La precision obtenue dans ces mesures, variant de 1,2 a 3 pour cent, on peut donc considerer le compteur 4 {pi} comme un instrument d'etalonnage tres satisfaisant. (auteur)

  19. Suomi NPP VIIRS active fire product status

    Science.gov (United States)

    Ellicott, E. A.; Csiszar, I. A.; Schroeder, W.; Giglio, L.; Wind, B.; Justice, C. O.

    2012-12-01

    We provide an overview of the evaluation and development of the Active Fires product derived from the Visible Infrared Imager Radiometer Suite (VIIRS) sensor on the Suomi National Polar-orbiting Partnership (SNPP) satellite during the first year of on-orbit data. Results from the initial evaluation of the standard SNPP Active Fires product, generated by the SNPP Interface Data Processing System (IDPS), supported the stabilization of the VIIRS Sensor Data Record (SDR) product. This activity focused in particular on the processing of the dual-gain 4 micron VIIRS M13 radiometric measurements into 750m aggregated data, which are fundamental for active fire detection. Following the VIIRS SDR product's Beta maturity status in April 2012, correlative analysis between VIIRS and near-simultaneous fire detections from the Moderate Resolution Imaging Spectroradiometer (MODIS) on the NASA Earth Observing System Aqua satellite confirmed the expected relative detection rates driven primarily by sensor differences. The VIIRS Active Fires Product Development and Validation Team also developed a science code that is based on the latest MODIS Collection 6 algorithm and provides a full spatially explicit fire mask to replace the sparse array output of fire locations from a MODIS Collection 4 equivalent algorithm in the current IDPS product. The Algorithm Development Library (ADL) was used to support the planning for the transition of the science code into IDPS operations in the future. Product evaluation and user outreach was facilitated by a product website that provided end user access to fire data in user-friendly format over North America as well as examples of VIIRS-MODIS comparisons. The VIIRS fire team also developed an experimental product based on 375m VIIRS Imagery band measurements and provided high quality imagery of major fire events in US. By August 2012 the IDPS product achieved Beta maturity, with some known and documented shortfalls related to the processing of

  20. THE SUBJECTIVE HUMAN PRODUCTIVITY IN LEARNING ACTIVITIES

    Directory of Open Access Journals (Sweden)

    Olga Yurievna Galiullina

    2015-06-01

    Full Text Available The article discusses the relationship of divergent thinking and achievement in learning activities. J. Guilford and some Russian scientists, divergent thinking is understood as a common creative ability. To be creators, to initiate and carry out initial practice and other forms of specifically human activity is to be subject. This ability – the main characteristic of subjectivity. Proved the importance of the relationship of divergent thinking and achievement in learning activities, for disclosure of subject student productivity. The study found «positive» relationship between divergent thinking and academic performance of students of the middle classes and the «negative» relationship among elementary school students. As we know from the writings of SL Rubinstein and N. Bernstein, training activities associated with the mastery of relevant skills. Formation of skills takes time. Therefore subjective productivity in educational activity is observed in the textbooks of the middle classes and does not manifest itself in elementary school students.

  1. JAERI's activities on photon production data

    International Nuclear Information System (INIS)

    Shibata, Keiichi; Maekawa, Fujio; Niita, Koji

    1996-01-01

    Summarized are activities on photon production data at JAERI. The activities consists of evaluation of photon production data for JENDL Fusion File, benchmark tests of JENDL and FENDL-1 data, and calculation of photon production data in the framework of the Quantum Molecular Dynamics. The capture cross sections of 12 C and 16 O were evaluated for JENDL Fusion File by taking account of the direct radiative capture calculations obtained by A. Mengoni (ENEA). The presently evaluated data are in good agreement with the measurements of Igashira et al. in the keV region, describing the behaviour of p-wave capture which is in proportion to υ. Photon production data on Fe and Ni were updated for JENDL Fusion File by using a statistical-model calculations. According to the results of benchmark tests, the calculations with the updated data reproduce the integral measurements on gamma-ray heating. Benchmark tests of evaluated photon production data have been continued by analyzing the integral experimental performed at OKTAVIAN and FNS. The calculations with JENDL Fusion File are in good agreement with the integral measurements. Preliminary calculation of photon production data in the high energy region has been done in the framework of the Quantum Molecular Dynamics approach. The quasi-deuteron model was used to describe photon absorption in the low energy region. Above pion production threshold, pion production channels were included in the calculation. The neutron-proton bremsstrahlung obtained with the one-boson-exchange model was incorporated into QMD codes. (Abstract only)

  2. Compte-rendu de Dozo (Björn-Olav, Mesures de l’écrivain

    Directory of Open Access Journals (Sweden)

    Samuel Coavoux

    2012-01-01

    Full Text Available Mesures de l’écrivain est avant tout un texte méthodologique : un préambule aux travaux réunis dans un ouvrage précédent, La vie littéraire à la toise. Il a pour objectif d’éclairer les conditions et le processus de production des données sur la vie littéraire belge contenues dans la base du Collectif interuniversitaire d’étude du littéraire (CIEL, ainsi que quelques méthodes statistiques d’analyse sociologique mobilisant ces données. Ce faisant, il s’agit de montrer quel peut être l’intérêt...

  3. Active agents in common skin care products.

    Science.gov (United States)

    Draelos, Zoe Diana

    2010-02-01

    Skin care products are numerous and perplexing, yet the majority fall into the moisturizer category. Moisturizers are substances designed to improve and maintain the skin barrier. They serve as a vehicle for the delivery of active ingredients that minimize facial lines of dehydration, deliver photoprotection, and provide antioxidant properties. Moisturizers are based on occlusive substances, such as petrolatum and dimethicone, and humectant substances, such as glycerin, with a variety of sunscreens and botanicals for added functionality and marketing impact. This article reviews these common active agents. The plethora of over-the-counter skin care products available for patient purchase is overwhelming, yet there is certain commonality among 80 percent of the formulations. The majority of the products are moisturizers with added ingredients to support marketing claims. Whether the product is a facial foundation, an antiaging night cream, a sunscreen, a topical antioxidant, or a skin-lightening serum, the formulation is basically a moisturizer. Sunscreen is the most biologically active antiaging ingredient in skin care products, but the antiinflammatory and antioxidant effects of botanicals possess tremendous marketing appeal.

  4. Planetary surface exploration MESUR/autonomous lunar rover

    Science.gov (United States)

    Stauffer, Larry; Dilorenzo, Matt; Austin, Dave; Ayers, Raymond; Burton, David; Gaylord, Joe; Kennedy, Jim; Laux, Richard; Lentz, Dale; Nance, Preston

    Planetary surface exploration micro-rovers for collecting data about the Moon and Mars have been designed by the Department of Mechanical Engineering at the University of Idaho. The goal of both projects was to design a rover concept that best satisfied the project objectives for NASA/Ames. A second goal was to facilitate student learning about the process of design. The first micro-rover is a deployment mechanism for the Mars Environmental Survey (MESUR) Alpha Particle/Proton/X-ray (APX) Instrument. The system is to be launched with the 16 MESUR landers around the turn of the century. A Tubular Deployment System and a spiked-legged walker have been developed to deploy the APX from the lander to the Martian Surface. While on Mars, the walker is designed to take the APX to rocks to obtain elemental composition data of the surface. The second micro-rover is an autonomous, roving vehicle to transport a sensor package over the surface of the moon. The vehicle must negotiate the lunar terrain for a minimum of one year by surviving impacts and withstanding the environmental extremes. The rover is a reliable track-driven unit that operates regardless of orientation that NASA can use for future lunar exploratory missions. This report includes a detailed description of the designs and the methods and procedures which the University of Idaho design teams followed to arrive at the final designs.

  5. Planetary surface exploration: MESUR/autonomous lunar rover

    Science.gov (United States)

    Stauffer, Larry; Dilorenzo, Matt; Austin, Dave; Ayers, Raymond; Burton, David; Gaylord, Joe; Kennedy, Jim; Lentz, Dale; Laux, Richard; Nance, Preston

    1992-06-01

    Planetary surface exploration micro-rovers for collecting data about the Moon and Mars was designed by the Department of Mechanical Engineering at the University of Idaho. The goal of both projects was to design a rover concept that best satisfied the project objectives for NASA-Ames. A second goal was to facilitate student learning about the process of design. The first micro-rover is a deployment mechanism for the Mars Environmental SURvey (MESUR) Alpha Particle/Proton/X-ray instruments (APX). The system is to be launched with the sixteen MESUR landers around the turn of the century. A Tubular Deployment System and a spiked-legged walker was developed to deploy the APX from the lander to the Martian surface. While on Mars the walker is designed to take the APX to rocks to obtain elemental composition data of the surface. The second micro-rover is an autonomous, roving vehicle to transport a sensor package over the surface of the moon. The vehicle must negotiate the lunar-terrain for a minimum of one year by surviving impacts and withstanding the environmental extremes. The rover is a reliable track-driven unit that operates regardless of orientation which NASA can use for future lunar exploratory missions. A detailed description of the designs, methods, and procedures which the University of Idaho design teams followed to arrive at the final designs are included.

  6. MESUR: USAGE-BASED METRICS OF SCHOLARLY IMPACT

    Energy Technology Data Exchange (ETDEWEB)

    BOLLEN, JOHAN [Los Alamos National Laboratory; RODRIGUEZ, MARKO A. [Los Alamos National Laboratory; VAN DE SOMPEL, HERBERT [Los Alamos National Laboratory

    2007-01-30

    The evaluation of scholarly communication items is now largely a matter of expert opinion or metrics derived from citation data. Both approaches can fail to take into account the myriad of factors that shape scholarly impact. Usage data has emerged as a promising complement to existing methods o fassessment but the formal groundwork to reliably and validly apply usage-based metrics of schlolarly impact is lacking. The Andrew W. Mellon Foundation funded MESUR project constitutes a systematic effort to define, validate and cross-validate a range of usage-based metrics of schlolarly impact by creating a semantic model of the scholarly communication process. The constructed model will serve as the basis of a creating a large-scale semantic network that seamlessly relates citation, bibliographic and usage data from a variety of sources. A subsequent program that uses the established semantic network as a reference data set will determine the characteristics and semantics of a variety of usage-based metrics of schlolarly impact. This paper outlines the architecture and methodology adopted by the MESUR project and its future direction.

  7. Trypanocidal Activity of Marine Natural Products

    Directory of Open Access Journals (Sweden)

    Amy J. Jones

    2013-10-01

    Full Text Available Marine natural products are a diverse, unique collection of compounds with immense therapeutic potential. This has resulted in these molecules being evaluated for a number of different disease indications including the neglected protozoan diseases, human African trypanosomiasis and Chagas disease, for which very few drugs are currently available. This article will review the marine natural products for which activity against the kinetoplastid parasites; Trypanosoma brucei brucei, T.b. rhodesiense and T. cruzi has been reported. As it is important to know the selectivity of a compound when evaluating its trypanocidal activity, this article will only cover molecules which have simultaneously been tested for cytotoxicity against a mammalian cell line. Compounds have been grouped according to their chemical structure and representative examples from each class were selected for detailed discussion.

  8. Production and characterization of granular activated carbon from activated sludge

    Directory of Open Access Journals (Sweden)

    Z. Al-Qodah

    2009-03-01

    Full Text Available In this study, activated sludge was used as a precursor to prepare activated carbon using sulfuric acid as a chemical activation agent. The effect of preparation conditions on the produced activated carbon characteristics as an adsorbent was investigated. The results indicate that the produced activated carbon has a highly porous structure and a specific surface area of 580 m²/g. The FT-IR analysis depicts the presence of a variety of functional groups which explain its improved adsorption behavior against pesticides. The XRD analysis reveals that the produced activated carbon has low content of inorganic constituents compared with the precursor. The adsorption isotherm data were fitted to three adsorption isotherm models and found to closely fit the BET model with R² equal 0.948 at pH 3, indicating a multilayer of pesticide adsorption. The maximum loading capacity of the produced activated carbon was 110 mg pesticides/g adsorbent and was obtained at this pH value. This maximum loading was found experimentally to steeply decrease as the solution pH increases. The obtained results show that activated sludge is a promising low cost precursor for the production of activated carbon.

  9. Determination of the concentration of {alpha} emitting radioactive aerosols; Mesure de la concentration des aerosols radioactifs emetteurs {alpha}

    Energy Technology Data Exchange (ETDEWEB)

    Labeyrie, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1953-06-15

    In the first part of this work the techniques used for the quantitative measurement of the concentrations of aerosols carrying short lived (radon or thoron daughters) or long lived (uranium) {alpha} radioactive emitters are described. In the second part the author investigates the problem of the determination of radon concentration in air by means of activity determinations on airborne dusts. Special reference is made to the measurement of the radon active deposit on two types of dusts (iron oxide (yellow) and uranium oxide) in small chambers (6 liters). In the third part are given data resulting from determinations of radon and thoron concentrations in atmospheric air in the south of Paris area using this method. (author) [French] Dans la premiere partie de ce travail on expose les techniques utilisees pour la mesure quantitative des concentrations d'aerosols contenant des emetteurs radioactifs {alpha}, tant pour ceux a vie courte (derives du radon ou du thoron) que pour ceux a vie longue (uranium). Dans la seconde partie on traite le probleme de la determination de la concentration de l'air en radon par la mesure de l'activite des poussieres ayant sejourne dans cet air. En particulier, on indique pour de petits volumes (6 litres) la proportion de depot actif du radon qui est fixee sur deux types de poussieres (limonite et oxyde d'uranium) en fonction de la concentration de celles-ci. Dans la troisieme partie on donne quelques exemples de mesure par cette methode de la concentration en radon et en thoron de l'atmosphere de la region parisienne. (auteur)

  10. ``Astrophysique sur Mesure'', E-learning in Astronomy and Astrophysics

    Science.gov (United States)

    Mosser, Benoît; Delsanti, Audrey; Guillaume, Damien; Balança, Christian; Balkowski, Chantal

    2011-06-01

    ``Astrophysique sur Mesure'' (astrophysics made-to-measure) is a set of e-learning programmes started 4 years ago at the Paris Observatory. In order to deliver attractive and efficient programmes, we have added many multimedia tools to usual lectures: animations, Java applets. The programmes are presented on two different platforms. The first one offers the content of all the lectures in free access. A second platform with restricted access is provided to registered students taking part in the e-learning program and benefiting from the help of tutors. The development of these programs helps to increase the sphere of influence of astronomy taught at the Paris Observatory, hence to increase the presence of astronomy in various degree courses. Instead of teaching classical astronomy lectures to a happy few, we can bring astronomy and astrophysics to a wider audience.

  11. Burner Characteristics for Activated Carbon Production

    Directory of Open Access Journals (Sweden)

    zakaria Supaat

    2017-01-01

    Full Text Available Carbonization process has become an important stage in developing activated carbon. However, existing burner are not efficient in time production which take 24 hours to15 days for charcoal production. Therefore, new design of burner/kilns is quite needed in order to produce larger number of charcoal in short time production, to improve charcoal quality regarding to the smooth surface area and pore volume. This research proposed new design burner which divided into two types which are vertical and horizontal types. Vertical is not completed by auto-rotating system while horizontal type is complete by auto-rotating and fume handling system. It developed using several equipment such as welding, oxy-cutting, drilling grinding and cutting machine. From the result of carbonization process shows that coconut shell charcoal need shorter time of 30 minutes as compared to palm shell charcoal of 2 h to completely carbonized. This result claim that the new design better than existing kiln that need longer time up to 24 h. The result of the palm and coconut shell charcoal believe will produce better properties of activated carbon in large surface area and higher total volume of pores. Therefore, this burner is high recommended for producing palm and coconut shell charcoal as well as other bio-based material.

  12. Activation product analysis in a mixed sample containing both fission and neutron activation products

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Samuel S.; Clark, Sue B.; Eggemeyer, Tere A.; Finn, Erin C.; Hines, C. Corey; King, Mathew D.; Metz, Lori A.; Morley, Shannon M.; Snow, Mathew S.; Wall, Donald E.; Seiner, Brienne N.

    2017-11-02

    Activation analysis of gold (Au) is used to estimate neutron fluence resulting from a criticality event; however, such analyses are complicated by simultaneous production of other gamma-emitting fission products. Confidence in neutron fluence estimates can be increased by quantifying additional activation products such as platinum (Pt), tantalum (Ta), and tungsten (W). This work describes a radiochemical separation procedure for the determination of these activation products. Anion exchange chromatography is used to separate anionic forms of these metals in a nitric acid matrix; thiourea is used to isolate the Au and Pt fraction, followed by removal of the Ta fraction using hydrogen peroxide. W, which is not retained on the first anion exchange column, is transposed to an HCl/HF matrix to enhance retention on a second anion exchange column and finally eluted using HNO3/HF. Chemical separations result in a reduction in the minimum detectable activity by a factor of 287, 207, 141, and 471 for 182Ta, 187W, 197Pt, and 198Au respectively, with greater than 90% recovery for all elements. These results represent the highest recoveries and lowest minimum detectable activities for 182Ta, 187W, 197Pt, and 198Au from mixed fission-activation product samples to date, enabling considerable refinement in the measurement uncertainties for neutron fluences in highly complex sample matrices.

  13. Une introduction à la convergence d'espaces métriques mesurés

    OpenAIRE

    Paulin, Frédéric

    2009-01-01

    Ce texte est une introduction élémentaire à la convergence d'espaces métriques compacts munis de mesures de probabilité, en suivant les textes de \\cite{Gro2,Fuk1,Vil,Stu,Jac}. Nous ne considérerons pas dans ces notes le cas d'espaces non compact et de mesures infinies, en renvoyant à ces références.

  14. Le temps mesurable, réversible, insaisissable ?

    CERN Document Server

    Fink, Martin; Leduc , Michèle

    2016-01-01

    Depuis l'Antiquité, la nature du temps a fasciné nombre de grands penseurs. Cet ouvrage expose ce que la physique est capable de dire aujourd'hui sur le sujet. La mesure du temps, ou plus exactement celle d'une durée, se fait grâce à des horloges atomiques dont l'exactitude peut atteindre une seconde sur plusieurs milliards d'années. Nous décrivons la façon dont s'effectue le transfert du temps qui permet la synchronisation d'horloges en différents points de la Terre ou de l'espace au milliardième de seconde près, ou même mieux. Les relativités, restreinte et générale, ont bouleversé notre conception du temps et ont un impact considérable sur certains problèmes de la vie quotidienne comme l'utilisation du GPS. On abandonne l'idée d'un temps absolu, le temps devient multiple et insaisissable, et peut-être même une illusion. Enfin la flèche du temps, ou l'irréversibilité, implique que les phénomènes physiques se déroulent toujours dans un sens déterminé, en relation avec la croissan...

  15. Mesure de la masse du boson $W^{\\pm}$ dans l'expérience ALEPH

    CERN Document Server

    Boumediene, D E

    2002-01-01

    Le modèle standard des interactions électrofaibles a permis d'unifier théoriquement deux des quatre interactions connues. Le boson W+- est décrit comme un ingrédient fondamental de cette théorie. Sa masse est un paramètre du modèle qui le conditionne. Inversement, cette masse peut être prédite. La comparaison d'une mesure suffisamment précise de cette masse avec les prédictions du modèle standard constitue alors un véritable test de la théorie et un défi expérimental. Par ailleurs, cette mesure peut être utilisée afin d'évaluer, dans le contexte du modèle standard voire de modèles super-symétriques, d'autres paramètres tels que la masse du boson de Higgs, à ce jour non découvert. Les mesures effectuées à LEP, au CERN permettront après combinaison d'atteindre une précision relative sur la masse du W+- de 0.02%. Cette mesure constitue une véritable mesure de précision. Cette thèse décrira la mesure effectuée dans l'expérience ALEPH. Toutes les techniques de mesure exploitées...

  16. Measurement of wave number spectrums; Mesure des spectres de nombres d'onde

    Energy Technology Data Exchange (ETDEWEB)

    Perceval, F. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-03-01

    To measure wave lengths in an ionized medium, the cross-correlation product of the signal collected by a fixed probe and that collected by a movable one exploring the medium, is carried out by an interferometer. In order to determine the various modes, we have made a device which computes the Fourier transform of the signal. The influence of the phase at the origin, of the damping of the signal and of the finite explored length has been studied in order to make a numerical calculation of the Fourier transform. (author) [French] Pour mesurer des longueurs d'onde dans un milieu ionise, nous effectuons a l'aide d'un interferometre un produit d'intercorrelation entre le signal collecte par une sonde fixe et celui d'une sonde mobile explorant le milieu. Afin de pouvoir determiner les differents modes constituant ces signaux, nous avons realise un dispositif qui effectue l'analyse de Fourier de tels enregistrements. L'influence de la phase a l'origine, de l'amortissement du signal et de la longueur finie d'exploration, a ete etudiee en vue du calcul numerique de la transformee de Fourier. (auteur)

  17. Urine: Waste product or biologically active tissue?

    Science.gov (United States)

    2018-03-01

    Historically, urine has been viewed primarily as a waste product with little biological role in the overall health of an individual. Increasingly, data suggest that urine plays a role in human health beyond waste excretion. For example, urine might act as an irritant and contribute to symptoms through interaction with-and potential compromise of-the urothelium. To explore the concept that urine may be a vehicle for agents with potential or occult bioactivity and to discuss existing evidence and novel research questions that may yield insight into such a role, the National Institute of Diabetes and Digestive and Kidney Disease invited experts in the fields of comparative evolutionary physiology, basic science, nephrology, urology, pediatrics, metabolomics, and proteomics (among others) to a Urinology Think Tank meeting on February 9, 2015. This report reflects ideas that evolved from this meeting and current literature, including the concept of urine quality, the biological, chemical, and physical characteristics of urine, including the microbiota, cells, exosomes, pH, metabolites, proteins, and specific gravity (among others). Additionally, the manuscript presents speculative, and hopefully testable, ideas about the functional roles of urine constituents in health and disease. Moving forward, there are several questions that need further understanding and pursuit. There were suggestions to consider actively using various animal models and their biological specimens to elaborate on basic mechanistic information regarding human bladder dysfunction. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

  18. Production, optimization, characterization and antifungal activity of ...

    African Journals Online (AJOL)

    SAM

    2014-04-02

    Apr 2, 2014 ... the present study, the antifungal activity of crude A. terrus chitinase was investigated against Apergillus niger, Aspergillus oryzae .... Chitinase activity was determined spectrophotometrically by estimating the amount of ..... characterization of two. Bifunctional chitinases lysozyme extracellularly produced by.

  19. Co-ordinating Product Developing Activities

    DEFF Research Database (Denmark)

    Terkelsen, Søren Bendix

    1996-01-01

    The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature......The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature...

  20. The Mediating Effects of Muscle Activities on the Relationship of Production Standard Time and Work Productivity

    Science.gov (United States)

    Nur, Nurhayati Mohd; Dawal, Siti Zawiah Md; Dahari, Mahidzal; Faraihan Zulkefli, Nur

    2017-10-01

    The aim of this study is to investigate the mediation effects of muscle activities on the relationship between production standard time and work productivity. The work productivity and muscle activities data are collected from twenty workers (10 males, 10 females) while performing industrial repetitive tasks at three different levels of production standard time corresponding to “normal”, “hard” and ‘very hard”. Mediation test was performed on the data and the results showed that muscle activities act as a mediator in the relationship between production standard time and work productivity. The result indicates the importance of assessing muscle activities in relation to work productivity at different levels of production standard time in order to optimize work productivity and reduce WMSDs risks.

  1. THE SUBJECTIVE HUMAN PRODUCTIVITY IN LEARNING ACTIVITIES

    OpenAIRE

    Olga Yurievna Galiullina

    2015-01-01

    The article discusses the relationship of divergent thinking and achievement in learning activities. J. Guilford and some Russian scientists, divergent thinking is understood as a common creative ability. To be creators, to initiate and carry out initial practice and other forms of specifically human activity is to be subject. This ability – the main characteristic of subjectivity. Proved the importance of the relationship of divergent thinking and achievement in learning activities, for disc...

  2. Identifying beauty quarks and measurement of the production cross-section of top quark pairs at {radical}s = 1.96 TeV in the D0 experiment; Etiquetage des quarks beaux et mesure de la section efficace de production de paires de quarks top a {radical}s=1,96 TeV dans l'experience DO

    Energy Technology Data Exchange (ETDEWEB)

    Greder, S

    2004-10-15

    The work presented in this thesis concerns the measurement of the top-anti-top production cross-section in the lepton + jets channel (electron and muon). The analysed data have been collected with the D0 detector between 2001 and 2004 at a center-of-mass energy of 1.96 TeV, at the Tevatron proton-antiproton collider located at Fermilab. These data correspond to an integrated luminosity of 160 pb-1 in each channel. Each top quark decays into a W boson and a b quark. The first part of this work has been focused on the elaboration of an algorithm, JLIP, aimed at identifying jets arising from b quark s decay products. This algorithm uses the impact parameter of the track s to assign a jet a probability that it originates from the primary interaction point. Its efficiency for top-anti-top events is about 45% with a rejected background of 99.7%. The second part of this work deals with the pre-selection step that allows isolating events which are likely to be compatible with a W+jets topology. Multi-jets and W+jets backgrounds are estimated from real data and simulation. The top pair production cross-section is extracted from candidate events that have at least three jets, one among them being tagged by the algorithm JLIP. Sources of systematics uncertainties have been studied in detail. Our results are the following, for the lepton + jets channel: {sigma}(tt-bar) = 8.28 (+1.31-1.21, stat) (+1.53-1.27, syst) (+0.53-0.53, lumi) pb. Results have been compared with the theoretical expectations and with other measurements performed in the D0 and CDF experiments. (author)

  3. Measurement of the production cross-section of heavy hadrons with the muon spectrometer of the ALICE detector at LHC; Mesure de la section efficace de production des hadrons lourds avec le spectrometre a muons d'ALICE au LHC

    Energy Technology Data Exchange (ETDEWEB)

    Manceau, L.

    2010-10-15

    Lattice quantum chromodynamics calculations predict a transition from the phase of hadronic matter to quark and gluon plasma for a temperature T {approx} 173 MeV and a vanishing baryonic potential. Ultra-relativistic heavy ion collisions allow to highlight this phase transition. Heavy flavours can be used to probe the first instants of the collisions where the temperature is the highest. The LHC will provide proton-proton and lead-lead collisions at unprecedented large energy ({radical}(s) = 14 TeV and {radical}(s{sub NN}) 5.5 TeV respectively). The ALICE detector is dedicated to heavy ion collisions but it can also measure proton-proton collisions. The detector includes a muon spectrometer. The spectrometer has been designed to measure heavy flavours. This work presents the performance of the spectrometer to measure beauty hadrons (B) and charmed hadrons (D) inclusive production cross-section in proton-proton collisions. The first step of the measurement consists in extracting heavy hadron decayed muon distributions. The next step consists in extrapolating these distributions to heavy hadrons inclusive production cross-section. This work also presents a preliminary study of the performance of the spectrometer for the measurement of the nuclear modification factor and the associated observable named R{sup B/D} in 0-10% central heavy ions collisions. Uncertainties and transverse impulsion range of extraction of the observables have been investigated. (author)

  4. Measures of Audiovisual Production Activities with Students.

    Science.gov (United States)

    Donoho, Grace

    1985-01-01

    Presents a case study of the library media program at Old High Elementary School, Bentonville, Arkansas, which uses production of audiovisual materials to build extrinsic motivation into reading programs for grades five and six and special education classes. Five measurement techniques used to evaluate the program's effectiveness are also…

  5. Performance of the Alice muon spectrometer. Weak boson production and measurement in heavy-ion collisions at LHC; Performance du spectrometre a muons d'ALICE. Production et mesure des bosons faibles dans des collisions d'ions lourds aupres du LHC

    Energy Technology Data Exchange (ETDEWEB)

    Conesa del valle, Z

    2007-07-15

    Lattice QCD predicts a transition from a hadronic phase to a Quark Gluon Plasma phase, QGP, for temperatures above 10{sup 13} K. Heavy-ion collisions are proposed to recreate it in laboratory. With such a purpose, the LHC (Large Hadron Collider) will provide Pb-Pb collisions at 5.5 TeV/u, and the ALICE experiment will permit to explore them. In particular, the ALICE muon spectrometer will permit to investigate the muon related probes (quarkonia, open beauty,...). The expected apparatus performances to measure muons and dimuons are discussed. A factorization technique is employed to unravel the different contributions to the global efficiency. Results indicate that the detector should be able to measure muons up to pT {approx} 100 GeV/c with a resolution of about 10 per cent. We show that weak bosons production could be measured for the first time in heavy-ion collisions. Single muon p{sub T} and dimuons invariant mass distributions will probe W and Z production. As mainly muons from b- and c-quarks decays will populate the intermediate-p{sub T} of 5 - 25 GeV/c, heavy quark in-medium energy loss calculations indicate that the single muon spectra would be suppressed by a factor 2-4 in the most central 0 - 10% Pb-Pb collisions at 5.5 TeV. However, for p{sub T} > 35 GeV/c the weak boson decays are predominant, and no suppression is expected. Estimations indicate that the b- and W-muons crossing point shifts down in transverse momenta by 5 to 7 GeV/c in the most central 0 - 10% Pb-Pb collisions at 5.5 TeV. (author)

  6. The Variation of Work Productivity and Muscle Activities at Different Levels of Production Target

    Science.gov (United States)

    Nur, Nurhayati Mohd; Dawal, Siti Zawiah Md; Dahari, Mahidzal; Zuhairah Mahmud Zuhudi, Nurul

    2017-10-01

    This paper aims to investigate the variation of work productivity and muscle activities among workers performing industrial repetitive tasks at four different levels of production target. The work productivity and muscle activities data were recorded from twenty workers at four levels of production target corresponding to “participative (PS1)”, “normal (PS2)”, “high (PS3)” and “very high (PS4)”. The results showed that worker productivity was found to increase at higher production target and there was a significant change (p activities were found to increase at higher production target and correspond to more discomfort and a higher rate of muscle fatigue. The results indicated that working with a higher production target results in higher worker productivity, but could lead to higher risk of WMSDs.

  7. Panorama 2009 - Exploration-production activities and markets

    International Nuclear Information System (INIS)

    2008-01-01

    After four years of heavy activity, growth on the upstream service and supply markets is slowing. At the end of 2008, the oil and gas price fell subsequent to the decline in demand for petroleum products. This is an indication that exploration-production activity will slow in 2009 and that the price of services - hence sales at service and supply companies - will drop

  8. Mesures en matière de taxation des produits du tabac en Afrique de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Mesures en matière de taxation des produits du tabac en Afrique de l'Ouest. En décembre 2007, le programme Recherche pour la lutte mondiale contre le tabac (RMCT) a entrepris une initiative afin de comprendre les facteurs cruciaux qui peuvent déterminer le succès de la lutte antitabac en Afrique subsaharienne.

  9. Qualification de l’instrumentation pour des mesures nanométriques

    CERN Document Server

    Bernard, E

    2009-01-01

    Prise en main de l’instrumentation dédiée aux mesures de vibrations dans le domaine du nanomètre et mise en service de nouveaux capteurs. Développement de l’acquisition des données sous Labview, et analyse des signaux dans le domaine fréquentiel sous Matlab.

  10. Mesure de la vitesse d'infiltration des eaux dans le sol : Cas des sols ...

    African Journals Online (AJOL)

    C'est donc une infiltration superficielle qui ne peut pas modifier la composition des eaux de l'aquifère. Ces sols sont alors favorables à une telle agriculture. Mots clés: mesure, vitesse, infiltration, sols, pollutions, eau, Niari, Congo. English Title: Measuring the speed of the water infiltration into the soil: case of the soil of the ...

  11. Measurement of double differential cross sections for light charged particles production in neutron induced reaction at 62.7 MeV on lead target; Mesures des sections efficaces doublement differentielles de production de particules chargees legeres lors de reactions induites par neutrons de 62.7 MeV sur cible de plomb

    Energy Technology Data Exchange (ETDEWEB)

    Kerveno, M

    2000-09-27

    In order to develop new options for nuclear waste management, studies are carrying out on the perfecting of hybrid systems (sub-critical reactor driven by accelerator). This thesis work takes place more precisely in the framework of nuclear data linked to hybrid systems development. Increasing the upper limit energy value (from 20 to 150 MeV) of data bases supposes that theoretical codes could have sufficient predictive power in this energy range. Thus it's necessary to measure new cross sections to constrain these codes. The experiment, performed at Louvain-la-Neuve Cyclotron, aims to determine the double differential cross sections for light charged particles production in neutron induced reactions at 62.7 MeV on natural lead target. The detection device consists of 6 NE102-CsI telescopes. Time of flight measurements are used to reconstruct the neutron energy spectra. The general framework (hybrid systems and associated nuclear data problematic) in which this work takes place is presented in a first part. The experimental set up used for our measurements is described in a second part. The three following parts are dedicated to the data analysis and double differential cross sections extraction. The particle discrimination, the energy calibration of detectors as the different corrections applied to the experimental spectra are related in details. And finally a comparative study between our experimental results and some theoretical predictions is presented. (author)

  12. Production of strange neutral particles and measurement of the polarization of {lambda} in the NOMAD experiment at CERN; Etude de la production des particules neutres etranges et mesure de la polarisation du {lambda} dans l'experience NOMAD au CERN

    Energy Technology Data Exchange (ETDEWEB)

    Lachaud, C

    2000-05-01

    The experiment NOMAD (CERN) is dedicated to the study of the neutrino-nucleon interaction. In these interactions many strange particles are produced: particularly K{sub s}{sup 0}, {lambda} and {lambda}-bar that are more easily detectable and this work is dedicated to them. The study of the polarization of {lambda} allows to go back to the measurements of spin transfer that are not well known. The identification of strange particles is difficult, 2 methods have been used in this work: likelihood ratios and {alpha}-asymmetry method. Once neutral strange particles were identified, their production rate (global and differential) have been made out, K{sup *{+-}}, and {sigma}{sup *{+-}} resonances and the decay of {xi} have been revealed. The second part of this work deals with the measurement of {lambda} polarization. The quality of the reconstruction of events and the cumulated statistics data allowed to give an accurate value of {lambda} polarization. A thorough study of the transverse polarization has been made and we see a dependence of the transverse impulse of {lambda} on the hadronic jet similar to that observed in hadronic collisions.

  13. Resonant production of sleptons in the run I of the DO experiment and identification of electrons in the run II; Recherche de production resonante de sleptons au Run I de D zero et identification et mesure des electrons au Run 2

    Energy Technology Data Exchange (ETDEWEB)

    Abdesselam, A

    2001-10-01

    This work deals with the resonant production of supersymmetric particles smuons and muon sneutrinos. The theoretical framework of this study rests on the model mSUGRA in which 5 parameters are considered: m{sub 0}, m{sub 1/2}, tan({beta}), A{sub 0}, sign({mu}) and one parameter for the violation of the R-parity. 2 analysis methods have been used: the traditional sequential analysis and the neuron network analysis that begins to be largely used in particle physics. This work is based on the experimental data collected during the run I of the experiment DO at the Tevatron (Fermilab, Usa). The value of luminosity is 94 pb{sup -1}. The general result is that no more events were detected than predicted by the standard model, so these results can be interpreted as a mean to draw limits for the values of the parameters. For instance values up to 230 GeV and 260 GeV are excluded for m{sub 0} and m{sub 1/2} respectively if the coupling constant {lambda}{sub 211} is worth 0.09, tan({beta}) = 2, sign({mu}) =-1 and A{sub 0} = 0. The interpretation can be made in terms of mass and the study shows that relative masses for {nu}-tilde{sub {mu}} and {chi}{sup 0}{sub 1} of 280 GeV and 112 GeV respectively are excluded with a 95% probability. Another part of this work deals with the identification of electron in the run II, different tools can be used, here the author chose the covariance matrix ( H matrix). (A.C.)

  14. Antiplasmodial activities of some products from Turreanthus ...

    African Journals Online (AJOL)

    We investigated the antiplasmodial activity of some pure compounds of Turreanthus africanus (Meliaceae), a plant that is used in traditional medicine to treat malaria in Southwest Cameroon. A phytochemical analysis of the methylene chloride: methanol (1:1) extract of the seeds of the plant yielded seven compounds.

  15. Production of activated carbon from microalgae

    OpenAIRE

    Hernández Férez, María del Remedio; Valdés Barceló, Francisco Javier; García, Angela N.; Marcilla, Antonio; Chápuli Fernández, Eloy

    2008-01-01

    Presentado como póster en el 11th Mediterranean Congress of Chemical Engineering, Barcelona 2008. Resumen publicado en el libro de actas del congreso. Activated carbon is an important filter material for the removal of different compounds such as hazardous components in exhaust gases, for purification of drinking water, waste water treatment, adsorption of pollution from liquid phases, in catalysis, electrochemistry or for gas storage and present an important demand. Theoretically, activat...

  16. Production and characterization of activated carbon from a ...

    African Journals Online (AJOL)

    In this study, the use of a bituminous coal for the production of activated carbons with chemical activation was investigated. The effects of process variables such as chemical reagents, activation temperature, impregnation ratio and carbonization temperature were investigated to optimize these parameters. The resultant ...

  17. BIOLOGICALLY ACTIVE SUBSTANCES OF SPIRIT PRODUCTION WASTE

    Directory of Open Access Journals (Sweden)

    A. S. Kayshev

    2014-01-01

    Full Text Available A content of biologically active compounds (BAC with signified pharmacological activity in distillers grains was proved. It is prospective for applications of these grains as a raw material resource of pharmaceuticals. A composition of BAC distillers grains received from wheat, corn, barley, millet at different spirit enterprises which use hydro fermentative grain processing. Considering polydispersity of distillers grains they were separated on solid and liquid phases preliminary. Physical and chemical characteristics of distillers grains' liquid base were identified. Elementary composition of distillers grains is signified by active accumulation of biogenic elements (phosphorus, potassium, magnesium, calcium, sodium, iron and low content of heavy metals. The solid phase of distillers grains accumulates carbon, hydrogen and nitrogen in high concentration. The liquid phase of distillers grains contains: proteins and amino acids (20-46%, reducing sugars (5,6%-17,5%, galacturonides (0,8-1,4%, ascorbic acid (6,2-11,4 mg%. The solid base of distillers grains contains: galacturonides (3,4-5,3%, fatty oil (8,4-11,1% with predomination of essential fatty acids, proteins and amino acids (2,1-2,5%, flavonoids (0,4-0,9%, tocopherols (3,4-7,7 mg%. A method of complex processing of distillers grains based on application of membrane filtering of liquid phase and liquid extraction by inorganic and organic solvents of solid phase, which allows almost full extraction of the sum of biologically active compounds (BAC from liquid phase (Biobardin BM and solid phase (Biobardin UL. Biobardin BM comprises the following elements: proteins and amino acids (41-69%, reducing sugars (3,5-15,6%, fatty oil (0,2-0,3%, flavonoids (0,2-0,7%, ascorbic acid (17-37 mg%. Biobardin UL includes: oligouronids (16,4-19,5%, proteins and amino acids (11-21%, fatty oil (3,2-4,9% which includes essential acids; flavonoids (0,6-1,5%, tocopherols (6,6-10,2 mg%, carotinoids (0,13-0,21 mg

  18. Antifouling Activity of Marine Natural Products

    KAUST Repository

    Qian, Pei-Yuan

    2012-01-01

    With the global ban of application of organotin-based marine coatings by International Maritime Organization in 2008, there is a practical and urgent need of identifying environmentally friendly low-toxic and nontoxic antifouling compounds for marine industries. Marine natural products have been considered as one of the most promising sources of antifouling compounds in recent years. In antifouling compound screening processes, bioassay systems often play most critical/vital roles in screening efforts. To meet various needs, a variety of bioassay systems have been developed and/or adopted in both research and commercial laboratories. In this chapter, we provide a brief outline of common bioassay procedures for both antimicrofouling and antimacrofouling assays, which can serve as a general guideline for setting up bioassay systems in laboratories engaged in antifouling compound screening. Some bioassay procedures currently practiced in various laboratories are not included in this book chapter for various reasons. Individual laboratories should modify bioassay protocols based on their research interests or needs. Nevertheless, we highly recommend the research laboratories to adapt high-throughput assays as much as possible for preliminary screening assays, followed by more complex bioassay processes using multiple target species. We argue strongly for studies in mode-of-action of antifouling compounds against settling propagules, which shall lead to discovery of molecular biomarkers (genes, proteins, receptors, or receptor system) and will allow us to design more targeted bioassay systems.

  19. Mesure et retroaction sur un qubit multi-niveaux en electrodynamique quantique en circuit non lineair

    Science.gov (United States)

    Boissonneault, Maxime

    L'electrodynamique quantique en circuit est une architecture prometteuse pour le calcul quantique ainsi que pour etudier l'optique quantique. Dans cette architecture, on couple un ou plusieurs qubits supraconducteurs jouant le role d'atomes a un ou plusieurs resonateurs jouant le role de cavites optiques. Dans cette these, j'etudie l'interaction entre un seul qubit supraconducteur et un seul resonateur, en permettant cependant au qubit d'avoir plus de deux niveaux et au resonateur d'avoir une non-linearite Kerr. Je m'interesse particulierement a la lecture de l'etat du qubit et a son amelioration, a la retroaction du processus de mesure sur le qubit de meme qu'a l'etude des proprietes quantiques du resonateur a l'aide du qubit. J'utilise pour ce faire un modele analytique reduit que je developpe a partir de la description complete du systeme en utilisant principalement des transfprmations unitaires et une elimination adiabatique. J'utilise aussi une librairie de calcul numerique maison permettant de simuler efficacement l'evolution du systeme complet. Je compare les predictions du modele analytique reduit et les resultats de simulations numeriques a des resultats experimentaux obtenus par l'equipe de quantronique du CEASaclay. Ces resultats sont ceux d'une spectroscopie d'un qubit supraconducteur couple a un resonateur non lineaire excite. Dans un regime de faible puissance de spectroscopie le modele reduit predit correctement la position et la largeur de la raie. La position de la raie subit les decalages de Lamb et de Stark, et sa largeur est dominee par un dephasage induit par le processus de mesure. Je montre que, pour les parametres typiques de l'electrodynamique quantique en circuit, un accord quantitatif requiert un modele en reponse non lineaire du champ intra-resonateur, tel que celui developpe. Dans un regime de forte puissance de spectroscopie, des bandes laterales apparaissent et sont causees par les fluctuations quantiques du champ electromagnetique

  20. Souci du social et action publique sur mesure

    Directory of Open Access Journals (Sweden)

    Bertrand Ravon

    2008-10-01

    Full Text Available L’engagement dans la lutte contre les problèmes sociaux s’est transformé. Avec l’individualisation et la territorialisation du traitement public des problèmes sociaux, se pose de plus en plus nettement la question d’une action publique de proximité, intersubjective. Mais plutôt que de renvoyer immédiatement les raisons de cette action publique sur mesure à une critique de la psychologisation des rapports sociaux ou du déclin des institutions, il s’agit de l’analyser comme une expérience publique, avec son lot d’actions et d’affects, de convictions et d’inquiétudes, de ressources et de préoccupations. La notion de souci s’impose alors pour tenir ce double mouvement de l’engagement, entre agir et subir, des épreuves qui nous conduisent dans l’action aux attentes qui nous y maintiennent. À partir de plusieurs exemples de formation de problèmes sociaux, l’article décline alors le souci des acteurs dans deux directions. D’une part, le souci de soi est analysé comme un engagement public au sens d’un travail d’orientation de soi dans un monde incertain via la reprise d’expériences sociales négatives. D’autre part, le souci commun est envisagé comme une « communauté de charge », c’est-à-dire comme un collectif d’action publique fondé non pas à partir de propriétés communes mais à partir d’affects partagés.“Concern” in the social sphere and public action adapted to the client: singular and critical public experience of social problemsCommitment in the struggle against social problems has changed. Along with the individualisation and territorial decentralisation of the public treatment of social problems, the question of very local and intersubjective public action has come more and more into focus. But rather than immediately relegating the reasons for this tailor-made version of social action to a critique of the increasing influence of psychological methods in social relations

  1. ACTIVE PACKAGING SYSTEM FOR MEAT AND MEAT PRODUCTS

    Directory of Open Access Journals (Sweden)

    Adriana Pavelková

    2012-10-01

    Full Text Available In the recent past, food packaging was used to enable marketing of products and to provide passive protection against environmental contaminations or influences that affect the shelf life of the products. However, unlike traditional packaging, which must be totally inert, active packaging is designed to interact with the contents and/or the surrounding environment. Interest in the use of active packaging systems for meat and meat products has increased in recent years. Active packaging systems are developed with the goal of extending shelf life for foods and increasing the period of time that the food is high quality. Developments in active packaging have led to advances in many areas, including delayed oxidation and controlled respiration rate, microbial growth, and moisture migration. Active packaging technologies include some physical, chemical, or biological action which changes interactions between a package, product, and/or headspace of the package in order to get a desired outcome. Active packaging systems discussed include oxygen scavengers, carbon dioxide scavengers and emitters, moisture control agents, flavour/odour absorbers and releasers  and antimicrobial packaging technologies. Active packaging is typically found in two types of systems; sachets and pads which are placed inside of packages, and active ingredients that are incorporated directly into packaging materials.  Recognition of the benefits of active packaging technologies by the food industry, development of economically viable packaging systems and increased consumer acceptance is necessary for commercial realisation of these packaging technologies.doi:10.5219/205

  2. Cyclic changes of steroid production activity in the ovary and ...

    African Journals Online (AJOL)

    The annual reproductive cycle of female Labeo capensiswas investigated using histochemical and endocrinological parameters. It was found that steroid production occurred in three localities in the ovary, namely, special theca cells, granulosa cells and interstitial cells. The 3β-HSD activity (steroid activity) in the granulosa ...

  3. Analysis awkward posture at food production activity using RULA ...

    African Journals Online (AJOL)

    If the workers continuously perform the activities throughout the working hours, they may experience prolonged standing which creates fatigue and causes an occupational hazard which includes slips and falls. The goal of this study was to identify awkward postures during food production activities. 40 workers with minimum ...

  4. Assessment of activation products in the Savannah River Site environment

    International Nuclear Information System (INIS)

    Carlton, W.H.; Denham, M.

    1996-07-01

    This document assesses the impact of radioactive activation products released from SRS facilities since the first reactor became operational late in 1953. The isotopes reported here are those whose release resulted in the highest dose to people living near SRS: 32 P, 51 Cr, 60 C, and 65 Zn. Release pathways, emission control features, and annual releases to the aqueous and atmospheric environments are discussed. No single incident has resulted in a major acute release of activation products to the environment. The releases were the result of normal operations of the reactors and separations facilities. Releases declined over the years as better controls were established and production was reduced. The overall radiological impact of SRS activation product atmospheric releases from 1954 through 1994 on the offsite maximally exposed individual can be characterized by a total dose of 0.76 mrem. During the same period, such an individual received a total dose of 14,400 mrem from non-SRS sources of ionizing radiation present in the environment. SRS activation product aqueous releases between 1954 and 1994 resulted in a total dose of 54 mrem to the offsite maximally exposed individual. The impact of SRS activation product releases on offsite populations also has been evaluated

  5. When Product Life Cycle Meets Customer Activity Cycle

    DEFF Research Database (Denmark)

    Tan, Adrian Ronald

    2007-01-01

    Manufacturing companies have traditionally focused their efforts on designing, developing and producing products to offer on the market. Today global competition and demands for greater company responsibility of products throughout their entire life cycle are driving manufacturing companies...... perspective value is created by supporting the customer’s activities related to the use of products. This is done through intangible services and knowledge intensification that ensures optimal operation and performance of products in relation to the individual customer’s activities. It is believed that PSS...... approaches can be a step on the path to sustainable development as this will enable and motivate companies to reuse, rationalise and enhance their products and services more efficiently throughout their life phases (Manzini & Vezzoli, 2002). Based on a year’s participation and observation in a development...

  6. MILK KEFIR: COMPOSITION, MICROBIAL CULTURES, BIOLOGICAL ACTIVITIES AND RELATED PRODUCTS

    Directory of Open Access Journals (Sweden)

    Maria Rosa Prado

    2015-10-01

    Full Text Available In recent years, there has been a strong focus on beneficial foods with probiotic microorganisms and functional organic substances. In this context, there is an increasing interest in the commercial use of kefir, since it can be marketed as a natural beverage that has health promoting bacteria. There are numerous commercially available kefir based-products. Kefir may act as a matrix in the effective delivery of probiotic microorganisms in different types of products. Also, the presence of kefir’s exopolysaccharides, known as kefiran, which has biological activity, certainly adds value to products. Kefiran can also be used separately in other food products and as a coating film for various food and pharmaceutical products. This article aims to update the information about kefir and its microbiological composition, biological activity of the kefir’s microflora and the importance of kefiran as a beneficial health substance.

  7. Milk kefir: composition, microbial cultures, biological activities, and related products.

    Science.gov (United States)

    Prado, Maria R; Blandón, Lina Marcela; Vandenberghe, Luciana P S; Rodrigues, Cristine; Castro, Guillermo R; Thomaz-Soccol, Vanete; Soccol, Carlos R

    2015-01-01

    In recent years, there has been a strong focus on beneficial foods with probiotic microorganisms and functional organic substances. In this context, there is an increasing interest in the commercial use of kefir, since it can be marketed as a natural beverage that has health promoting bacteria. There are numerous commercially available kefir based-products. Kefir may act as a matrix in the effective delivery of probiotic microorganisms in different types of products. Also, the presence of kefir's exopolysaccharides, known as kefiran, which has biological activity, certainly adds value to products. Kefiran can also be used separately in other food products and as a coating film for various food and pharmaceutical products. This article aims to update the information about kefir and its microbiological composition, biological activity of the kefir's microflora and the importance of kefiran as a beneficial health substance.

  8. Non-intrusive measurement of tritium activity in waste drums by modelling a {sup 3}He leak quantified by mass spectrometry; Mesure non intrusive de l'activite de futs de dechets trities par modelisation d'une fuite {sup 3}He et sa quantification par spectrometrie de masse

    Energy Technology Data Exchange (ETDEWEB)

    Demange, D

    2002-07-03

    This study deals with a new method that makes it possible to measure very low tritium quantities inside radioactive waste drums. This indirect method is based on measuring the decaying product, {sup 3}He, and requires a study of its behaviour inside the drum. Our model considers {sup 3}He as totally free and its leak through the polymeric joint of the drum as two distinct phenomena: permeation and laminar flow. The numerical simulations show that a pseudo-stationary state takes place. Thus, the {sup 3}He leak corresponds to the tritium activity inside the drum but it appears, however, that the leak peaks when the atmospheric pressure variations induce an overpressure in the drum. Nevertheless, the confinement of a drum in a tight chamber makes it possible to quantify the {sup 3}He leak. This is a non-intrusive measurement of its activity, which was experimentally checked by using reduced models, representing the drum and its confinement chamber. The drum's confinement was optimised to obtain a reproducible {sup 3}He leak measurement. The gaseous samples taken from the chamber were purified using selective adsorption onto activated charcoals at 77 K to remove the tritium and pre-concentrate the {sup 3}He. The samples were measured using a leak detector mass spectrometer. The adaptation of the signal acquisition and the optimisation of the analysis parameters made it possible to reach the stability of the external calibrations using standard gases with a {sup 3}He detection limit of 0.05 ppb. Repeated confinement of the reference drums demonstrated the accuracy of this method. The uncertainty of this non-intrusive measurement of the tritium activity in 200-liter drums is 15% and the detection limit is about 1 GBq after a 24 h confinement. These results led to the definition of an automated tool able to systematically measure the tritium activity of all storage waste drums. (authors)

  9. Structuring front-end innovation activities throughout strategic product planning

    Directory of Open Access Journals (Sweden)

    Thaisa Rodrigues

    Full Text Available Abstract Strategic product planning (SPP for new product development (NPD in the front-end of innovation (FEI is a great challenge for managers and practitioners. This article analyzes the structuring process of FEI activities during SPP. A research was carried out with 78 industries from both food and furniture in Brazil. Our study revealed that FEI activities are structured in an intricate network with a high level of complexity and interdependence. The large amount of activities and the complexity in structuring them denote that companies are concerned to reduce uncertainties and risks intensifying the planning phase.

  10. Bonheur et progrès : mesurer le bien-être au Bhoutan et au Canada ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    31 janv. 2011 ... Mesurer le bien-être. Au Bhoutan, ce tableau de bord porte un nom plein de charme. C'est le bonheur national brut (BNB). Le royaume est-himalayen, bouddhiste, compte environ 800 000 sujets. Enclavé entre les deux pays les plus populeux de la planète, il vient de mettre fin au long isolement qu'il s'était ...

  11. Conception, réalisation et validation d'un dispositif de mesure de ...

    African Journals Online (AJOL)

    RÉSUMÉ. Dans le cadre de ses travaux de recherche dans le domaine de la Compatibilité Electromagnétique (CEM), l'IRSEEM (Institut de Recherche en Systèmes Electroniques Embarqués) a développé un banc de mesure automatisé. Il permet de caractériser en totalité le champ électromagnétique proche rayonné par ...

  12. Mesure magnétique du sextupôle rotatif no.1-2083

    CERN Document Server

    Chritin, R; Patron, G; CERN. Geneva. SPS and LEP Division

    1998-01-01

    Lorsque cet aimant nous a été livré afin d'être soumis à un certain nombre de mesures, ses caractéristiques connues se limitaient à celles situées dans l'annexe 1. Il correspond à des sextupôles, INT 2170254 AB L orientables récupérés de l'ancienn

  13. Des collectivités forestières du Nigeria prennent des mesures pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Des collectivités forestières du Nigeria prennent des mesures pour réduire les émissions de carbone. 08 juin 2016. Image. Deforestation in Nigeria. Foreign and Commonwealth Office. En Afrique subsaharienne, il est crucial de conserver et de protéger les forêts pour assurer la durabilité des moyens de subsistance des ...

  14. Enriching step-based product information models to support product life-cycle activities

    Science.gov (United States)

    Sarigecili, Mehmet Ilteris

    The representation and management of product information in its life-cycle requires standardized data exchange protocols. Standard for Exchange of Product Model Data (STEP) is such a standard that has been used widely by the industries. Even though STEP-based product models are well defined and syntactically correct, populating product data according to these models is not easy because they are too big and disorganized. Data exchange specifications (DEXs) and templates provide re-organized information models required in data exchange of specific activities for various businesses. DEXs show us it would be possible to organize STEP-based product models in order to support different engineering activities at various stages of product life-cycle. In this study, STEP-based models are enriched and organized to support two engineering activities: materials information declaration and tolerance analysis. Due to new environmental regulations, the substance and materials information in products have to be screened closely by manufacturing industries. This requires a fast, unambiguous and complete product information exchange between the members of a supply chain. Tolerance analysis activity, on the other hand, is used to verify the functional requirements of an assembly considering the worst case (i.e., maximum and minimum) conditions for the part/assembly dimensions. Another issue with STEP-based product models is that the semantics of product data are represented implicitly. Hence, it is difficult to interpret the semantics of data for different product life-cycle phases for various application domains. OntoSTEP, developed at NIST, provides semantically enriched product models in OWL. In this thesis, we would like to present how to interpret the GD & T specifications in STEP for tolerance analysis by utilizing OntoSTEP.

  15. Novel condensation products having high activity to insolubilize proteins and protein-insolubilized products

    Energy Technology Data Exchange (ETDEWEB)

    Krasnobajew, V.; Boeniger, R.

    1980-01-01

    According to the invention a substantially more active product with respect to the fixing or insolubilization pf proteins, including enzymes, is obtained when 1,3 phenylenediamine is condensed with glutardialdehyde. One application of the process is the enzymatic hydrolysis of lactose in milk products by lactase.

  16. Risk of the different activities related to energy production

    International Nuclear Information System (INIS)

    Tenaglia, G.

    1983-01-01

    After recalling briefly the concept of risk and explaining the relevant terminology currently in use, the paper deals with the application of the concept of risk to the activities related to energy production. Particular emphasis is placed on the necessity of considering the entire cycle of an energy source, the different aspects that the negative consequences of an activity may entail, as well as the context, mainly territorial and socio-economical, in wich an activity is performed. Moreover the paper presents, schematically and in qualitative terms, the main risk of the different activities related to energy production. More details are given about potentially dangerous activities, nowdays emerging, like -for example- transportation and storage of flammable liquids, whether refrigerated or not. Finally, the difficulties of comparing risks having different probabilities and consequences are considered, as well as the meaning to be assigned, in any case, to comparison among riks [fr

  17. Production and characterization of cellulolytic activities produced by ...

    African Journals Online (AJOL)

    Hind

    2013-01-30

    Jan 30, 2013 ... Algerian hot spring was used for the production of cellulases by submerged fermentation on Mandels medium with ... These activities were stable at 50°C after 5 h incubation in a pH range of 3.0 to 6.0 and 4.0 to. 6.0, respectively. ... components in a complex in which the product of one enzyme reaction ...

  18. Entropy Production and Fluctuation Theorems for Active Matter

    Science.gov (United States)

    Mandal, Dibyendu; Klymko, Katherine; DeWeese, Michael R.

    2017-12-01

    Active biological systems reside far from equilibrium, dissipating heat even in their steady state, thus requiring an extension of conventional equilibrium thermodynamics and statistical mechanics. In this Letter, we have extended the emerging framework of stochastic thermodynamics to active matter. In particular, for the active Ornstein-Uhlenbeck model, we have provided consistent definitions of thermodynamic quantities such as work, energy, heat, entropy, and entropy production at the level of single, stochastic trajectories and derived related fluctuation relations. We have developed a generalization of the Clausius inequality, which is valid even in the presence of the non-Hamiltonian dynamics underlying active matter systems. We have illustrated our results with explicit numerical studies.

  19. Comparative assessment of antioxidant activity of chicory products

    Directory of Open Access Journals (Sweden)

    Z. A. Badretdinova

    2016-01-01

    Full Text Available There are various methods for determining the antioxidant activity. They are differing by the source of oxidation, oxidized compounds and methods for the measurement of oxidized compounds. Methods for determination of antioxidant activity provide a wide range of results, so the evaluation of the antioxidant activity should be carried out in several ways, and the results should be interpreted with caution. In assessing antioxidant capacity is necessary to consider not only the nature and content of the reducing agent in the test facility, but also the possibility of their mutual influence. The objects of research in this research work were Instant chicory (Leroux, Fried chicory (Leroux, Instant chicory (LLC Favorit, Instant chicory (LLC SlavKofe, Instant chicory with hawthorn (Iceberg Ltd and K, Instant chicory (LLC Flagistom, Instant chicory (Ltd. Around the World, Instant chicory (LLC Beta +, Chicory flour (Leroux, Chicory flour. Antioxidant activity of the products of chicory determined by spectrophotometric (using adrenaline and 2,2 – diphenyl- 1-picrylhydrazyl, and amperometric methods. These results indicate that chicory products possess antioxidant activity but not give fully correlated with each other results. The highest antioxidant activity have fried products from chicory – Instant chicory (LLC SlavKofe and Instant chicory with hawthorn (Iceberg Ltd and K. No fried products from chicory (Chicory flour (Leroux have lower antioxidant activity then fried products from chicory. Because during frying new compounds are formed – chikoreol, which comprises acetic and valeric acid, acrolein and furfural, furfuryl alcohol, diacetyl. Best convergence results provide spectrophotometric methods using epinephrine and 2,2 – diphenyl-1-picrylhydrazyl.

  20. Exploration and production activities and market - Panorama 2008

    International Nuclear Information System (INIS)

    2007-01-01

    Following two banner years for the oil service and supply sector, marked by strong activity and a substantial increase in prices, the Exploration and Production market continued at a frenetic pace in 2007, although certain local markets retreated. In 2008, activity should stay high and prices should start stabilizing. With services in short supply, companies in the sector have been able to shift the balance of power with oil firms in their favor

  1. Neutron activation analysis (NAA), radioisotope production via neutron activation (PNA) and fission product gas-jet (GJA)

    Energy Technology Data Exchange (ETDEWEB)

    Gaeggeler, H.W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1996-11-01

    Three different non-diffractive applications of neutrons are outlined, neutron activation analysis, production of radionuclides, mostly for medical applications, and production of short-lived fission nuclides with a so-called gas-jet. It is shown that all three devices may be incorporated into one single insert at SINQ due to their different requests with respect to thermal neutron flux. Some applications of these three facilities are summarized. (author) 3 figs., 1 tab., 8 refs.

  2. Activation of waste brewer's yeast Saccharomyces cerevisiae for bread production

    Directory of Open Access Journals (Sweden)

    Popov Stevan D.

    2005-01-01

    Full Text Available The waste brewer's yeast S. cerevisiae (activated and non-activated was compared with the commercial baker's yeast regarding the volume of developed gas in dough, volume and freshness stability of produced bread. The activation of waste brewer's yeast resulted in the increased volume of developed gas in dough by 100% compared to non-activated brewer's yeast, and the obtained bread is of more stable freshness compared to bread produced with baker's yeast. The activation of BY affects positively the quality of produced bread regarding bread volume. The volume of developed gas in dough prepared with the use of non-activated BY was not sufficient, therefore, it should not be used as fermentation agent, but only as an additive in bread production process for bread freshness preservation. Intense mixing of dough results in more compressible crumb 48 hrs after baking compared to high-speed mixing.

  3. Review: Production and functionality of active peptides from milk.

    Science.gov (United States)

    Muro Urista, C; Álvarez Fernández, R; Riera Rodriguez, F; Arana Cuenca, A; Téllez Jurado, A

    2011-08-01

    In recent years, research on the production of active peptides obtained from milk and their potential functionality has grown, to a great extent. Bioactive peptides have been defined as specific protein fragments that have a positive impact on body functions or conditions, and they may ultimately have an influence on health. Individual proteins of casein or milk-derived products such as cheese and yogurt have been used as a protein source to study the isolation and activity of peptides with several applications. Currently, the milk whey waste obtained in the production of cheese also represents a protein source from which active peptides could be isolated with potential industrial applications. The active properties of milk peptides and the results found with regard to their physiological effects have led to the classification of peptides as belonging to the group of ingredients of protein nature, appropriate for use in functional foods or pharmaceutical formulations. In this study, the main peptides obtained from milk protein and the past research studies about its production and biological activities will be explained. Second, an analysis will be made on the methods to determinate the biological activities, the separation of bioactive peptides and its structure identification. All of these form the base required to obtain synthetic peptides. Finally, we explain the experimental animal and human trials done in the past years. Nevertheless, more research is required on the design and implementation of equipment for the industrial production and separation of peptides. In addition, different authors suggest that more emphasis should therefore be given to preclinical studies, proving that results are consistent and that effects are demonstrated repeatedly by several research human groups.

  4. Antioxidant Activity of Natural Products against Aluminium Fluoride ...

    African Journals Online (AJOL)

    Evaluation of antioxidant potential of natural products against Aluminium fluoride (AlF4) induced oxidative stress in albino mice were represented in the present study. Gossypin, Quercetin dehydrate, (-)-Epicatechin gallate, Gallic acid and Suramin sulphate (G-protein inhibitor) were evaluated for antioxidant activity by ...

  5. Antioxidant activity of maillard reaction products from lysine-glucose ...

    African Journals Online (AJOL)

    Maillard reaction (MR) was carried out in L-lysine-D-glucose (Lys-Glu) model system heated at 120°C for 0 to 10 h without pH control. Optical property (UV-Vis absorbance and fluorescence) development of MR was monitored. Antioxidant activity of maillard reaction products (MRPs) was investigated by a series of in vitro ...

  6. production and characterization of activated carbon from leather ...

    African Journals Online (AJOL)

    dell

    39.70%) and sawdust (25.10 – 37.20%). Activated carbon from these precursors, were also evaluated for percentage ash, fixed carbon, pH and bulk density. Adsorption studies carried out with methylene blue indicate that low temperature carbonization of precursors such as leather buffing waste favour production of carbon ...

  7. Assessment of rural children in agricultural production activities in ...

    African Journals Online (AJOL)

    This study assessed the participation of rural children in agricultural production activities in Ogbomoso zone of Oyo state, Nigeria with a focus on the vocational concept, belief and development of the youth from the environment in tandem with the realities of the modern day in comparison with the occupation of the old ...

  8. Production and characterization of cellulolytic activities produced by ...

    African Journals Online (AJOL)

    The indigenous cellulolytic fungus Trichoderma longibrachiatum (GHL) isolated from soil near an Algerian hot spring was used for the production of cellulases by submerged fermentation on Mandels medium with cellulose Avicel (1%) as the sole carbon source. Endoglucanase and filter paper activities of the wild-type ...

  9. Eliciting Production of L2 Target Structures through Priming Activities

    Science.gov (United States)

    McDonough, Kim; Trofimovich, Pavel; Neumann, Heike

    2015-01-01

    This study focuses on the pedagogical applications of structural priming research in an English for academic purposes (EAP) context, investigating whether priming activities are an effective tool for eliciting production of target grammatical structures. University students across four EAP classes carried out a total of 6 information-exchange…

  10. Can aquatic worms enhance methane production from waste activated sludge?

    NARCIS (Netherlands)

    Serrano, Antonio; Hendrickx, Tim L.G.; Elissen, Hellen; Laarhoven, Bob; Buisman, Cees J.N.; Temmink, Hardy

    2016-01-01

    Although literature suggests that aquatic worms can help to enhance the methane production from excess activated sludge, clear evidence for this is missing. Therefore, anaerobic digestion tests were performed at 20 and at 30 °C with sludge from a high-loaded membrane bioreactor, the aquatic worm

  11. Optimization of companies’ activity on development of electronic product

    Directory of Open Access Journals (Sweden)

    K.V. Nalivaychenko

    2012-02-01

    Full Text Available The article considers modern processes of informatization of activity for business companies. There are generalized the makes of world companies, which create information technologies in global information environment: the electronic information product containing an universal development algorithm for it, is most effective. It is found that companies prefer opened program codes.

  12. Can aquatic worms enhance methane production from waste activated sludge?

    Science.gov (United States)

    Serrano, Antonio; Hendrickx, Tim L G; Elissen, Hellen H J; Laarhoven, Bob; Buisman, Cees J N; Temmink, Hardy

    2016-07-01

    Although literature suggests that aquatic worms can help to enhance the methane production from excess activated sludge, clear evidence for this is missing. Therefore, anaerobic digestion tests were performed at 20 and at 30°C with sludge from a high-loaded membrane bioreactor, the aquatic worm Lumbriculus variegatus, feces from these worms and with mixtures of these substrates. A significant synergistic effect of the worms or their feces on methane production from the high-loaded sludge or on its digestion rate was not observed. However, a positive effect on low-loaded activated sludge, which generally has a lower anaerobic biodegradability, cannot be excluded. The results furthermore showed that the high-loaded sludge provides an excellent feed for L. variegatus, which is promising for concepts where worm biomass is considered a resource for technical grade products such as coatings and glues. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Considerations for higher efficiency and productivity in research activities.

    Science.gov (United States)

    Forero, Diego A; Moore, Jason H

    2016-01-01

    There are several factors that are known to affect research productivity; some of them imply the need for large financial investments and others are related to work styles. There are some articles that provide suggestions for early career scientists (PhD students and postdocs) but few publications are oriented to professors about scientific leadership. As academic mentoring might be useful at all levels of experience, in this note we suggest several key considerations for higher efficiency and productivity in academic and research activities. More research is needed into the main work style features that differentiate highly productive scientists and research groups, as some of them could be innate and others could be transferable. As funding agencies, universities and research centers invest large amounts of money in order to have a better scientific productivity, a deeper understanding of these factors will be of high academic and societal impact.

  14. JV Task 90 - Activated Carbon Production from North Dakota Lignite

    Energy Technology Data Exchange (ETDEWEB)

    Steven Benson; Charlene Crocker; Rokan Zaman; Mark Musich; Edwin Olson

    2008-03-31

    The Energy & Environmental Research Center (EERC) has pursued a research program for producing activated carbon from North Dakota lignite that can be competitive with commercial-grade activated carbon. As part of this effort, small-scale production of activated carbon was produced from Fort Union lignite. A conceptual design of a commercial activated carbon production plant was drawn, and a market assessment was performed to determine likely revenue streams for the produced carbon. Activated carbon was produced from lignite coal in both laboratory-scale fixed-bed reactors and in a small pilot-scale rotary kiln. The EERC was successfully able to upgrade the laboratory-scale activated carbon production system to a pilot-scale rotary kiln system. The activated carbon produced from North Dakota lignite was superior to commercial grade DARCO{reg_sign} FGD and Rheinbraun's HOK activated coke product with respect to iodine number. The iodine number of North Dakota lignite-derived activated carbon was between 600 and 800 mg I{sub 2}/g, whereas the iodine number of DARCO FGD was between 500 and 600 mg I{sub 2}/g, and the iodine number of Rheinbraun's HOK activated coke product was around 275 mg I{sub 2}/g. The EERC performed both bench-scale and pilot-scale mercury capture tests using the activated carbon made under various optimization process conditions. For comparison, the mercury capture capability of commercial DARCO FGD was also tested. The lab-scale apparatus is a thin fixed-bed mercury-screening system, which has been used by the EERC for many mercury capture screen tests. The pilot-scale systems included two combustion units, both equipped with an electrostatic precipitator (ESP). Activated carbons were also tested in a slipstream baghouse at a Texas power plant. The results indicated that the activated carbon produced from North Dakota lignite coal is capable of removing mercury from flue gas. The tests showed that activated carbon with the greatest

  15. Entropy production of active particles and for particles in active baths

    Science.gov (United States)

    Pietzonka, Patrick; Seifert, Udo

    2018-01-01

    Entropy production of an active particle in an external potential is identified through a thermodynamically consistent minimal lattice model that includes the chemical reaction providing the propulsion and ordinary translational noise. In the continuum limit, a unique expression follows, comprising a direct contribution from the active process and an indirect contribution from ordinary diffusive motion. From the corresponding Langevin equation, this physical entropy production cannot be inferred through the conventional, yet here ambiguous, comparison of forward and time-reversed trajectories. Generalizations to several interacting active particles and passive particles in a bath of active ones are presented explicitly, further ones are briefly indicated.

  16. Distinct Patterns of Brain Activity Characterise Lexical Activation and Competition in Spoken Word Production

    NARCIS (Netherlands)

    Piai, V.; Roelofs, A.P.A.; Jensen, O.; Schoffelen, J.M.; Bonnefond, M.

    2014-01-01

    According to a prominent theory of language production, concepts activate multiple associated words in memory, which enter into competition for selection. However, only a few electrophysiological studies have identified brain responses reflecting competition. Here, we report a magnetoencephalography

  17. SOME IMPORTANTS DEFINITIONS AND MESUREMENT METHODS OF CORPORATE REPUTATION

    Directory of Open Access Journals (Sweden)

    MIHAELA SANDU

    2012-12-01

    Full Text Available Reputation is one of the most important intangible corporate active. In the literature we can find different definitions and methods of measurement for reputation. In this paper we will emphasize some of them. We will see how increased the importance of reputation in the last years. We will see how important this asset is for the company and how a positive reputation determines the competitive advantage for the company.

  18. 14C specific activity of farm products and marine products collected from the Rokkasho area in Aomori prefecture

    International Nuclear Information System (INIS)

    Muranaka, Takeshi; Honda, Kazuya

    1996-01-01

    We investigated 14 C specific activity of farm products and marine products which were collected from the Rokkasho area in Aomori prefecture from 1988 to 1990. The measured 14 C specific activity of farm products was almost equal to one another with the averaged 14 C specific activity of 0.261 [Bq/g·C]. On the other hand, 14 C specific activity of marine products was slightly lower than those of farm products. Especially that of squid was the lowest among studied marine products. This may be due to the low 14 C specific activity of the sea water surrounding squid. (author)

  19. ACTIVITY OF NATURAL PRODUCTS AGAINST SOME PHYTOPATHOGENIC FUNGI.

    Science.gov (United States)

    La Torre, A; Caradonia, F; Gianferro, M; Molinu, M G; Battaglia, V

    2014-01-01

    The requirement of environmental protection and food safety is perceived with always major interest by public opinion and it is consistent with European Union legislation on the sustainable use of pesticides (Directive 2009/128/EC). This directive requires member states to promote low pesticide-input, giving priority to non-chemical methods and low risk plant protection products. In order to contribute to the achievement of these objectives antifungal activity of natural substances, characterized by a good toxicological and ecotoxicological profile, was tested. Essential oil of Melaleuca alternifolia, essential oil of Syzygium aromaticum and extract from Mimosa tenuiflora were tested against Alternaria alternata, Botrytis cinerea and Fusarium oxysporum f. sp. lycopersici (races 1 and 2). In vitro tests involved determination of radial growth of the colonies of fungi in the presence of varying concentrations of tested products in agar media and determination of germination percentage in the presence of tested product at various concentrations. The products based on essential oil of M. alternifolia were also tested in vivo on tomato fruits wounded and artificially inoculated with A. alternata or with B. cinerea. The in vitro tests showed the antifungal activity of both essential oils instead the extract from M. tenuiflora exhibited poor antifungal activity and only against A. alternata and B. cinerea. The results on tomato fruits showed inhibition of grey mould and black mould by essential oil of M. alternifolia. The antifungal activity increased with increasing concentrations. In conclusion, the obtained results in the present study showed promising prospects for the utilisation of investigated products to reduce the using of antifungal chemicals and to achieve a more sustainable use of pesticides.

  20. Mesure de l'activité entrepreneuriale en Égypte et en Tunisie | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Mesure de l'activité entrepreneuriale en Égypte et en Tunisie. Ce projet permettra d'examiner l'évolution de l'activité entrepreneuriale dans la foulée du printemps arabe. L'entreprenariat est l'un des principaux moteurs du développement économique, mais on s'y est peu attardé dans la région, et le manque de données a ...

  1. On line tritium measurement; La mesure du tritium en ligne

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2011-07-01

    Berthold Technologies has developed a new beacon able to measure the activity of tritium in the atmosphere. The real-time measurement will allow the operator to be warned of the exceeding of radiation thresholds. The air sample to be measured is mixed with a counting gas (generally argon/methane) and pumped through a proportional counter. The device counts the electric impulses due to the interaction between the beta particles generated by the tritium and the counting gas. The detection threshold is 500 Bq/m{sup 3} for a counting time of 1 hour. The device also allows the operator to get an emission spectrum of the air sample. (A.C.)

  2. Mesures de taux de production d'éléments gazeux et volatiles lors de réactions induites par des protons de 1 et 1,4 GeV sur des cibles épaisses de plomb-bismuth liquides

    CERN Document Server

    Tall, Yoro

    2008-01-01

    The integrated project EUROTRANS (European Research Programme for the Transmutation of High Level Nuclear Waste in an Accelerator Driven System) of the 6th Euratom Framework Programme aims to demonstrate the transmutation of radioactive waste in ADS (Accelerator Driven Sub-critical system). It will carry out a first advanced design of an experimental facility to demonstrate the technical feasibility of transmutation, and will produce a conceptual design of an industrial facility dedicated to transmutation. An ADS consists of three fundamental elements: the accelerator of protons, the sub-critical core and the spallation target which one molten lead-bismuth concept is studied by the SUBATECH (physique SUBAtomique et des TECHnologies associées) laboratory in Nantes. The irradiation of molten lead-bismuth target with energetic proton beam generates volatile and radioactive residues. In order to determine experimentally the production rates of gas and volatile elements following a spallation reaction in a lead-b...

  3. Activation of air and concrete in medical isotope production facilities

    Science.gov (United States)

    Dodd, Adam C.; Shackelton, R. J.; Carr, D. A.; Ismail, A.

    2017-05-01

    Medical isotope facilities operating in the 10 to 25 MeV proton energy range have long been used to generate radioisotopes for medical diagnostic imaging. In the last few years the beam currents available in commercially available cyclotrons have increased dramatically, and so the activation of the materials within cyclotron vaults may now pose more serious radiological hazards. This will impact the regulatory oversight of cyclotron operations, cyclotron servicing and future decommissioning activities. Air activation could pose a hazard to cyclotron staff. With the increased cyclotron beam currents it was necessary to examine the issue more carefully. Therefore the ways in which radioactivity may be induced in air by neutron reactions and neutron captures were considered and it was found that the dominant mechanism is neutron capture on Ar-40. A study of the activation of the air by neutron capture on Ar-40 within a cyclotron vault was performed using the MCNP Monte Carlo code. The neutron source energy spectrum used was from the production of the widely used F-18 PET isotope. The results showed that the activation of the air within a cyclotron vault does not pose a significant radiological hazard at the beam intensities currently in use and shows how ventilation affects the results. A second MCNP study on the activation of ordinary concrete in cyclotron vaults by neutron capture was made with a view to determining the optimum thickness of borated polyethylene to reduce neutron activation on both the inner surfaces of the vault and around production targets. This is of importance in decommissioning cyclotrons and therefore in the design of new cyclotron vaults. The distribution of activation on the walls as a function of the source position was also studied. Results are presented for both borated and regular polyethylene, and F-18 and Tc-99 neutron spectra.

  4. Conformation-activity relationships of polyketide natural products.

    Science.gov (United States)

    Larsen, Erik M; Wilson, Matthew R; Taylor, Richard E

    2015-08-01

    Polyketides represent an important class of secondary metabolites that interact with biological targets connected to a variety of disease-associated pathways. Remarkably, nature's assembly lines, polyketide synthases, manufacture these privileged structures through a combinatorial mixture of just a few structural units. This review highlights the role of these structural elements in shaping a polyketide's conformational preferences, the use of computer-based molecular modeling and solution NMR studies in the identification of low-energy conformers, and the importance of conformational analogues in probing the bound conformation. In particular, this review covers several examples wherein conformational analysis complements classic structure-activity relationships in the design of biologically active natural product analogues.

  5. Panorama 2011: Exploration-production: activities and markets

    International Nuclear Information System (INIS)

    Saniere, A.; Serbutoviez, S.

    2011-01-01

    After a year of economic crisis in 2009, oil companies saw renewed demand and are reporting increased investment in 2010. Exploration-production activity is resuming, at a pace that varies by sector, but prices for goods and services remain depressed as a result of existing over-capacity. In particular, developments in Brazil and Iraq and growth in unconventional gas are helping to maintain the level of activity. Meanwhile, the catastrophic oil spill in the Gulf of Mexico is leading to tighter regulations and safety standards in offshore drilling. (author)

  6. Panorama 2010: Activities and markets in exploration-production

    International Nuclear Information System (INIS)

    Saniere, A.; Serbutoviez, S.

    2010-01-01

    At year-end 2008, a sharp decrease in oil and gas demand coupled with a credit crunch caused the postponement of many exploration-production projects. 2009 was marked by substantial over-capacity in terms of equipment and installations, which drove down the level of activity, the price of services and the income of suppliers. The year is nonetheless perceived as marking a lull in an upward cycle and capital expenditure is expected to rise slightly in 2010. (author)

  7. Accelerator Production and Separations for High Specific Activity Rhenium-186

    Energy Technology Data Exchange (ETDEWEB)

    Jurisson, Silvia S. [Univ. of Missouri, Columbia, MO (United States); Wilbur, D. Scott [Univ. of Washington, Seattle, WA (United States)

    2016-04-01

    Tungsten and osmium targets were evaluated for the production of high specific activity rhenium-186. Rhenium-186 has potential applications in radiotherapy for the treatment of a variety of diseases, including targeting with monoclonal antibodies and peptides. Methods were evaluated using tungsten metal, tungsten dioxide, tungsten disulfide and osmium disulfide. Separation of the rhenium-186 produced and recycling of the enriched tungsten-186 and osmium-189 enriched targets were developed.

  8. Dissolution test for low-activity waste product acceptance

    International Nuclear Information System (INIS)

    Ebert, W. L.

    1998-01-01

    We have measured the mean and standard deviation of the solution concentrations of B, Na, and Si attained in replicate dissolution tests conducted at temperatures of 20, 40, and 70 C, for durations of 3 and 7 days, and at glass/water mass ratios of 1:10 and 1:1. These and other tests were conducted to evaluate the adequacy of the test methods specified in privatization contracts and to develop a data base that can be used to evaluate the reliability of reported results for tests performed on the waste products. Tests were conducted with a glass that we formulated to be similar to low-activity waste products that will be produced during the remediation of Hanford tank wastes. Statistical analyses indicated that, while the mean concentrations of B, Na, and Si were affected by the values of test parameters, the standard deviation of replicate tests was not. The precision of the tests was determined primarily by uncertainties in the analysis of the test solutions. Replicate measurements of other glass properties that must be reported for Hanford low-activity waste products were measured to evaluate the possible adoption of the glass used in these tests as a standard test material for the product acceptance process

  9. NPASS: natural product activity and species source database for natural product research, discovery and tool development.

    Science.gov (United States)

    Zeng, Xian; Zhang, Peng; He, Weidong; Qin, Chu; Chen, Shangying; Tao, Lin; Wang, Yali; Tan, Ying; Gao, Dan; Wang, Bohua; Chen, Zhe; Chen, Weiping; Jiang, Yu Yang; Chen, Yu Zong

    2018-01-04

    There has been renewed interests in the exploration of natural products (NPs) for drug discovery, and continuous investigations of the therapeutic claims and mechanisms of traditional and herbal medicines. In-silico methods have been employed for facilitating these studies. These studies and the optimization of in-silico algorithms for NP applications can be facilitated by the quantitative activity and species source data of the NPs. A number of databases collectively provide the structural and other information of ∼470 000 NPs, including qualitative activity information for many NPs, but only ∼4000 NPs are with the experimental activity values. There is a need for the activity and species source data of more NPs. We therefore developed a new database, NPASS (Natural Product Activity and Species Source) to complement other databases by providing the experimental activity values and species sources of 35 032 NPs from 25 041 species targeting 5863 targets (2946 proteins, 1352 microbial species and 1227 cell-lines). NPASS contains 446 552 quantitative activity records (e.g. IC50, Ki, EC50, GI50 or MIC mainly in units of nM) of 222 092 NP-target pairs and 288 002 NP-species pairs. NPASS, http://bidd2.nus.edu.sg/NPASS/, is freely accessible with its contents searchable by keywords, physicochemical property range, structural similarity, species and target search facilities. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  10. Optimization of polyhydroxylalkanoates production from excess activated sludge

    International Nuclear Information System (INIS)

    Chua, H.; Yu, P.H.F.; Ma, C.K.

    2000-01-01

    Polyhydroxy alkanoates (PHAS) produced by microbial fermentation are biodegradable and can be used as environmentally-friendly substitutes for conventional plastics to resolve the environmental problems associated with plastics wastes. However, widespread applications of PHA are hampered by high production cost. In this study, activated sludge bacteria from a conventional wastewater treatment process were induced, by controlling the carbon-nitrogen (C:N) ratio in the reactor liquor, to accumulate PHA as a low-cost source of biodegradable plastic. Specific polymer yield increased to a maximum of O.27 g polymer/g dry cell mass when the C:N ratio was increased from 24 to 144, whereas specific growth yield decreased with increasing C:N ratio. An optimum C:N ratio of 96 provided the highest overall polymer production yield of 0.09 g polymer/g carbonaceous substrate consumed. Moreover, an intermittent nitrogen feeding program was established to further optimize the polymer volumetric productivity. The overall polymer production yield of O.11 g polymer/g carbonaceous substrate consumed was achieved under C:N ratio of 96 by feeding nitrogen in the reactor liquor once every 4 cycles. While reducing the production costs of biodegradable plastics, this technique also reduced the amount of excess sludge generated from the wastewater treatment process as the polymer portion of biomass was extracted for use. (Author)

  11. Sustaining Competitiveness Through product Development Activities Within Malaysian Automotive Suppliers

    Directory of Open Access Journals (Sweden)

    Norizah Mohamad

    2012-01-01

    Full Text Available The local automotive suppliers are facing a number of important challenges such asglobalisation, new requirement in market specifications and the competition brought about by theAsean Free Trade Area (AFTA agreements. In an effort to enhance the competitiveness of themanufacturing sector, the government has implemented the Second Industrial Master Plan, IMP2(1996-2005. The focus of the IMP2 is more on innovation and applications of new technologies, sothat industries can move up the value chain of their activities. Innovative capabilities achieved fromcompanies’ new product development activities have been recognized to be crucial for companies tosustain their competitiveness and organisational success. The importance of product development ismost obvious in the context of the discussion on the competitiveness of the Malaysian automotivesuppliers. The study will focus on the small medium enterprises (SMEs that make up more than 60 %of these automotive suppliers. The study is to determine the extensiveness of the suppliers’ productdevelopment activities by examining the involvement of the suppliers in customer’s productdevelopment activities. Consequently, the impact of this involvement to the competitiveness of thesuppliers is examined. The results were established based from a survey to parts and componentssuppliers of Proton, the Malaysian car national assembler. The study has shown that the SMEs wereinvolved from the early stages of the product development process that is during the design stage. Theproduct development efforts have shown to contribute towards increasing firms’ market share andfirms were also able to gain a better understanding of future product demand. A significant number ofthe suppliers have managed to penetrate the export market. Unfortunately, among the respondents,there is only one system supplier. This indicates that, either the technological capabilities of theSMEs still needed upgrading for the requirement as

  12. Plant products and secondary metabolites with acaricide activity against ticks.

    Science.gov (United States)

    Rosado-Aguilar, J A; Arjona-Cambranes, K; Torres-Acosta, J F J; Rodríguez-Vivas, R I; Bolio-González, M E; Ortega-Pacheco, A; Alzina-López, A; Gutiérrez-Ruiz, E J; Gutiérrez-Blanco, E; Aguilar-Caballero, A J

    2017-04-30

    The present review documents the results of studies evaluating the acaricidal activity of different plant products and secondary metabolites against ticks that are resistant and susceptible to conventional acaricides. Studies published from 1998 to 2016 were included. The acaricidal activity of plant extracts, essential oils and secondary compounds from plants have been evaluated using bioassays with ticks in the larval and adult stages. There is variable effectiveness according to the species of plant and the concentrations used, with observed mortalities ranging from 5 to 100% against the Rhipicephalus (Boophilus), Amblyomma, Dermacentor, Hyalomma, and Argas genera. A number of plants have been reported to cause high mortalities and/or affect the reproductive capacity of ticks in the adult phase. In the majority of these trials, the main species of plants evaluated correspond to the families Lamiaceae, Fabaceae, Asteraceae, Piperaceae, Verbenaceae, and Poaceae. Different secondary metabolites such as thymol, carvacrol, 1,8-cineol and n-hexanal, have been found to be primarily responsible for the acaricidal activity of different essential oils against different species of ticks, while nicotine, dibenzyldisulfide and dibenzyltrisulfide have been evaluated for plant extracts. Only thymol, carvacrol and 1,8-cineol have been evaluated for acaricidal activity under in vivo conditions. The information in the present review allows the conclusion that the secondary metabolites contained in plant products could be used as an alternative for the control of ticks that are susceptible or resistant to commercial acaricides. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Mesures magnétiques du dipôle DH-LEAR 1

    CERN Document Server

    Chritin, R; Patron, G; CERN. Geneva. SPS and LEP Division

    1998-01-01

    Ce dipôle fait partie d'un ensemble de deux aimants semblables récupérés du LEAR et destinés à être utilisés en dipôles verticaux dans le projet AD. Ce sont des aimants feuilletés, fixés sur un socle composé d'un bloc d'aluminium massif de 10cm d'épaisseur et d'une épaisse tôle en acier munie de pieds réglables. L'aimant en question a donc été mesuré avec ce socle. Les mesures réalisées ont consisté à vérifier les caractéristiques de cet aimant, et en particulier ses polarités électriques et magnétiques, sa courbe de magnétisation, ainsi que l'homogénéité de l'induction intégrée sur l'axe X. Un test d'échauffement a également permis de déterminer son courant d'utilisation maximum.

  14. Utilisation d'une sonde fluorimétrique benthique (la BenthoTorch, bbe) pour mesurer la croissance des diatomées, algues vertes et cyanobactéries périphytiques en plans d'eau

    OpenAIRE

    Roubeix, V.

    2015-01-01

    / Une sonde fluorimétrique benthique, la BenthoTorch (bbe) a été acquise par le pôle Onema-Irstea d'Hydroécologie des Plans d'eau pour développer un indice fonctionnel de production primaire dans les plans d'eau. Cet indice sera basé sur la dynamique de croissance du périphyton sur des substrats artificiels. Il constituerait un outil de diagnostic du fonctionnement écologique des systèmes lentiques, particulièrement utile dans le cadre du suivi de mesures de restauration. La BenthoTorch me...

  15. Mesure de la Polarisation des Lambda Produits dans les Collisions Positron-Electron AU Lep a L'aide du Detecteur Opal

    Science.gov (United States)

    Vandenplas, Denis

    Le Modele Standard est le cadre theorique general qui, jusqu'a present, a permis l'interpretation de tous les resultats experimentaux en physique des hautes energies. Cette theorie decrit, entre autres, la production d'une paire de particules elementaires, formee d'un quark et d'un antiquark, a partir de la desintegration de l'un des bosons mediateurs de l'interaction faible, le Z^0. Cependant, dans ce cas precis, la transformation subsequente des quarks primaires en particules reelles, un processus appele hadronisation, n'est decrite qu'a l'aide de modeles phenomenologiques. Afin de sonder les mecanismes de l'hadronisation, cette these presente la mesure du transfert du spin d'un quark etrange primaire a une particule appelee Lambda lors des desintegrations hadroniques du Z^0. L'etude a ete realisee dans le cadre de la collaboration OPAL, une des quatre experiences menees au collisionneur LEP, la ou des electrons et des positrons sont acceleres jusqu'a une energie commune, sqrt{s} = {rm E_ {cm}}, voisine de l'energie de production du rm Z^0, M_{Z ^0} egale a 91.3 GeV. La theorie electrofaible precise la direction du spin, c'est-a-dire la polarisation, d'un quark etrange primaire provenant de la desintegration d'un Z ^0. Quant a lui, le modele des quarks etablit que l'orientation du spin d'un Lambda est directement reliee a la polarisation du quark etrange dont il provient. La question est de determiner dans quelle mesure la polarisation du quark primaire est transmise au Lambda a la suite du processus de l'hadronisation, decrit dans le cadre de la ChromoDynamique Quantique. Une estimation, qui tient compte de tous ces differents aspects theoriques, evalue a 30% la polarisation des Lambda dont l'impulsion est superieure a 15 GeV/c. La mesure experimentale de la polarisation repose sur l'identification des Lambda a partir de la reconstitution de la desintegration Lambdato ppi^-. Ce processus, qui se deroule par le biais de l'interaction faible, viole la parite car

  16. Production and efficiency of organic compost generated by millipede activity

    Directory of Open Access Journals (Sweden)

    Luiz Fernando de Sousa Antunes

    2016-05-01

    Full Text Available ABSTRACT: The putrefactive activity of organisms such as diplopods in the edaphic macrof auna can be leveraged to promote the transformation of agricultural and urban waste into a low-cost substrate for the production of vegetable seedlings. This research aimed to evaluate: (1 the quantity of Gervais millipedes ( Trigoniulus corallinus needed to produce an acceptable quantity of organic compost; (2 the main physical and chemical characteristics of different compost types; and (3 compost efficiency in the production of lettuce seedlings. The first experiment lasted 90 days and was conducted using 6.5L of Gliricidia, 6.5L of Flemingia, 13.5L of grass cuttings, 4.5L of cardboard, 4.5L of coconut husk, and 4.5L of corncob. Treatments consisting of 0, 0.10, 0.30, 0.50, and 0.90L of millipedes were applied. This experiment compared millicompost and vermicompost, using four repetitions. After 23 days, the heights of grown lettuce plants and the weights of the fresh and dry mass of above ground lettuce and of the roots were assessed. A millipede volume of 0.1L proved to be sufficient for the production of an acceptable volume of organic compost. However, the addition of greater volumes leads to increased calcium, magnesium, and phosphorous content. Millicompost has similar physicochemical characteristics those of vermicompost, and both are equally efficient as a substrate for the production of lettuce seedlings.

  17. Hypocapnia induces caspase-3 activation and increases Abeta production.

    Science.gov (United States)

    Xie, Zhongcong; Moir, Robert D; Romano, Donna M; Tesco, Giuseppina; Kovacs, Dora M; Tanzi, Rudolph E

    2004-01-01

    At least half of all cases of early onset (<60) familial Alzheimer's disease (FAD) are caused by any of over 150 mutations in three genes: the amyloid precursor protein (APP), presenilin 1 (PS1), and presenilin 2 (PS2). Mutant forms of PS1 have been shown to sensitize cells to apoptotic cell death. We investigated the effects of hypocapnia, a risk factor for both cognitive and neurodevelopment deficits, on caspase-3 activation, apoptosis, and amyloid beta-protein (Abeta) production, and assessed the influence of the PS1Delta9 FAD mutation on these effects. For this purpose, we exposed stably transfected H4 human neuroglioma cells to conditions consistent with hypocapnia (PCO2<40 mm Hg) and hypocapnia plus hypoxia (PO2<21%). Hypocapnia (20 mm Hg CO2 for 6 h) induced caspase-3 activation and apoptosis; the PS1Delta9 FAD mutation significantly potentiated these effects. Moreover, the combination of hypocapnia (20 mm Hg CO2) and hypoxia (5%O2) induced caspase-3 activation and apoptosis in a synergistic manner. Hypocapnia (5 and 20 mm Hg CO2 for 6 h) also led to an increased Abeta production. The findings suggest that hypocapnia (e.g. during general anesthesia) could exacerbate AD neuropathogenesis. Copyright (c) 2004 S. Karger AG, Basel.

  18. Innovative activities for teaching anatomy of speech production.

    Science.gov (United States)

    Skinder-Meredith, Amy E

    2010-01-01

    Courses in anatomy have traditionally relied on lectures and cadaver dissection laboratories. In speech and hearing sciences, there tends to be less access to cadavers than in medical schools and other allied health professions. It is more typical to use anatomical models, diagrams and lecture slides. Regardless of the resources available, anatomy is a subject that lends itself to hands-on learning. This article briefly reviews teaching methods and describes a variety of innovative activities to enhance learning of anatomical concepts and clinical relevance of anatomy for speech production. Teaching strategies and activities were developed to capitalize on students' multimodal learning preferences as revealed by responses to a survey administered to 49 undergraduates in the beginning of an anatomy of speech production course. At the end of the semester, students completed a second survey. A five-point Likert scale was used to assess the usefulness of each activity as a learning tool or level of clinical relevance and the level of enjoyability. The responses were overwhelmingly positive with level of usefulness and level of clinical relevance rated higher on average than the level of enjoyment.

  19. Production of mullite from natural raw materials using mechanical activation

    International Nuclear Information System (INIS)

    Feitosa, G.; Pinheiro, D.G.; Chinelatto, A.L.; Chinelatto, A.S.A

    2009-01-01

    Mullite, ceramic structure consisting by alumina and silica, is present in different ceramic industry, as refractory, white ceramic, titles and advanced ceramics. This is because this material presents high resistance mechanical and high resistance in high temperatures, beyond low expansion coefficients and thermal conductivity. On the other hand, the mullite production needs high temperatures. This work had as objective the production of mullite from natural raw materials, using mechanical activation. Bauxite and quartz had been mixed in the stoichiometric composition and the mixture was submitted to high energy milling for different times. Then non milled powders and milled powders had been sintered in different temperatures. The characterization was made by X Ray diffraction and scanning electronic microscopy. The results demonstrated that the high energy milling affects the mullite formation, decreasing the temperature in that it is formed. (author)

  20. Land processes distributed active archive center product lifecycle plan

    Science.gov (United States)

    Daucsavage, John C.; Bennett, Stacie D.

    2014-01-01

    The U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center and the National Aeronautics and Space Administration (NASA) Earth Science Data System Program worked together to establish, develop, and operate the Land Processes (LP) Distributed Active Archive Center (DAAC) to provide stewardship for NASA’s land processes science data. These data are critical science assets that serve the land processes science community with potential value beyond any immediate research use, and therefore need to be accounted for and properly managed throughout their lifecycle. A fundamental LP DAAC objective is to enable permanent preservation of these data and information products. The LP DAAC accomplishes this by bridging data producers and permanent archival resources while providing intermediate archive services for data and information products.

  1. Plant compounds insecticide activity against Coleoptera pests of stored products

    Energy Technology Data Exchange (ETDEWEB)

    Moreira, Marcio Dionizio; Picanco, Marcelo Coutinho; Guedes, Raul Narciso Carvalho; Campos, Mateus Ribeiro de; Silva, Gerson Adriano; Martins, Julio Claudio [Universidade Federal de Vicosa (UFV), MG (Brazil). Dept. de Biologia Animal]. E-mail: marcio.dionizio@gmail.com; picanco@ufv.br; guedes@ufv.br; mateusc3@yahoo.com.br; agronomiasilva@yahoo.com.br

    2007-07-15

    The objective of this work was to screen plants with insecticide activity, in order to isolate, identify and assess the bioactivity of insecticide compounds present in these plants, against Coleoptera pests of stored products: Oryzaephilus surinamensis L. (Silvanidae), Rhyzopertha dominica F. (Bostrichidae) and Sitophilus zeamais Mots. (Curculionidae). The plant species used were: basil (Ocimum selloi Benth.), rue (Ruta graveolens L.), lion's ear (Leonotis nepetifolia (L.) R.Br.), jimson weed (Datura stramonium L.), baleeira herb (Cordia verbenacea L.), mint (Mentha piperita L.), wild balsam apple (Mormodica charantia L.), and billy goat weed or mentrasto (Ageratum conyzoides L.). The insecticide activity of hexane and ethanol extracts from those plants on R. dominica was evaluated. Among them, only hexane extract of A. conyzoides showed insecticide activity; the hexane extract of this species was successively fractionated by silica gel column chromatography, for isolation and purification of the active compounds. Compounds 5,6,7,8,3',4',5'-heptamethoxyflavone; 5,6,7,8,3'-pentamethoxy-4',5'-methilenedioxyflavone and coumarin were identified. However, only coumarin showed insecticide activity against three insect pests (LD{sub 50} from 2.72 to 39.71 mg g{sup -1} a.i.). The increasing order of insects susceptibility to coumarin was R. dominica, S. zeamais and O. surinamensis. (author)

  2. Hanford Immobilized Low-Activity Waste Product Acceptance Test Plan

    International Nuclear Information System (INIS)

    Peeler, D.

    1999-01-01

    'The Hanford Site has been used to produce nuclear materials for the U.S. Department of Energy (DOE) and its predecessors. A large inventory of radioactive and mixed waste, largely generated during Pu production, exists in 177 underground single- and double-shell tanks. These wastes are to be retrieved and separated into low-activity waste (LAW) and high-level waste (HLW) fractions. The DOE is proceeding with an approach to privatize the treatment and immobilization of Handord''s LAW and HLW.'

  3. Trypsin inhibitory activity of artemisinin and its biotransformed product

    International Nuclear Information System (INIS)

    Shahwar, D.; Raza, M.A.

    2013-01-01

    Summary: Artemisinin (1 ), a sesquiterpene lactone is an important constituent of anti-malarial drugs. In the present study, it was extracted from aerial parts of Artemisia roxburghiana Besser. Biotransformation of artemisinin ( 1 ) was carried out in the culture of Aspergillus niger GC-4 which yielded 5-hydroxy artemisinin (2 ) The structures of 1-2 were confirmed through spectral studies. Both compounds were screened against trypsin using colorimetric method. The biotransformed product 2 showed significant protease inhibitory activity with 53.5 +- 1.6% inhibition and IC/sub 50/ = 0.29 +- 0.02 mM as compared to artemisinin (20.4 +- 0.3% inhibition). (author)

  4. De l’apprentissage à la mesure du caring: réflexion épistémo-ontologique

    Directory of Open Access Journals (Sweden)

    PAWEL KROL

    2009-04-01

    Full Text Available Cet article, inspiré d’une perspective postmoderne, pose un regard critique sur le progrès et expose comment le développement frénétique et l’emploi peu questionné des technologies, ont concouru à l’objectivation de la personne, la déshumanisation des services de santé, la main mise sur la formation infirmière ainsi qu’ à l’instrumentalisation des pratiques de soins modernes. Cette réflexion épistémo-ontologique questionne l’étude de l’apprentissage du caring et problématise sa mesure où le postpositivisme semble s’imposer empiriquement, soulevant ainsi des interrogations quant à la cohérence épistémologique entre la théorie du caring et sa mesure. Enfin, nous avançons que la mesure la mesure du caring constitue une difficulté substantielle renfermant des incohérences épistémo-ontologiques qui demeurent incommensurables.

  5. Active Desiccant-Based Preconditioning Market Analysis and Product Development

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, J.

    2001-01-11

    The Phase 1 report (ORNL/Sub/94-SVO44/1), completed earlier in this program, involved a comprehensive field survey and market analysis comparing various specialized outdoor air handling units. This initial investigation included conventional cooling and reheat, conventional cooling with sensible recovery, total energy recovery systems (passive desiccant technology) and various active desiccant systems. The report concluded that several markets do promise a significant sales opportunity for a Climate Changer-based active desiccant system offering. (Climate Changer is a registered trademark of Trane Company.) This initial market analysis defined the wants and needs of the end customers (design engineers and building owners), which, along with subsequent information included in this report, have been used to guide the determination of the most promising active desiccant system configurations. This Phase 2 report begins with a summary of a more thorough investigation of those specific markets identified as most promising for active desiccant systems. Table 1 estimates the annual sales potential for a cost-effective product line of active desiccant systems, such as that built from Climate Changer modules. The Product Development Strategy section describes the active desiccant system configurations chosen to best fit the needs of the marketplace while minimizing system options. Key design objectives based on market research are listed in this report for these active desiccant systems. Corresponding performance goals for the dehumidification wheel required to meet the overall system design objectives are also defined. The Performance Modeling section describes the strategy used by SEMCO to design the dehumidification wheels integrated into the prototype systems currently being tested as part of the U.S. Department of Energy's Advanced Desiccant Technology Program. Actual performance data from wheel testing was used to revise the system performance and energy analysis

  6. Production and activities of chitinases and hydrophobins from Lecanicillium lecanii.

    Science.gov (United States)

    Rocha-Pino, Zaizy; Vigueras, Gabriel; Shirai, Keiko

    2011-08-01

    The production of chitinases and hydrophobins from Lecanicillium lecanii was influenced by the cultivation method and type of carbon source. Crude enzyme obtained from solid-substrate culture presented activities of exochitinases (32 and 51 kDa), endochitinases (26 kDa), β-N-acetylhexosaminidases (61, 80, 96 and 111 kDa). Additionally, submerged cultures produced exochitinases (32 and 45 kDa), endochitinases (10 and 26 kDa) and β-N-acetylhexosaminidases (61, 96 and 111 kDa). β-N-acetylhexosaminidases activity determined in solid-substrate culture with added chitin was ca. threefold (7.58 ± 0.57 U mg(-1)) higher than submerged culture (2.73 + 0.57 U mg(-1)). Similarly, hydrophobins displayed higher activities in solid-substrate culture (627.3 ± 2 μg protein mL(-1)) than the submerged one (57.4 ± 4.7 μg protein mL(-1)). Molecular weight of hydrophobins produced in solid-substrate culture was 7.6 kDa and they displayed surface activity on Teflon.

  7. QSAR Study of the Biologically Active Organosulfurs in Natural Products

    Directory of Open Access Journals (Sweden)

    Fakhr M. Abu-Awwad

    2010-01-01

    Full Text Available The biological activities of two sets of a total of 30 different polysulfides were investigated using QSAR. The semiempirical AM1 in Gaussian 2003 for windows was used to optimize the structures whereas a subsequent calculation of hundreds of various types of descriptors at the density functional (B3LYP/6-31G* using CODESSA package was employed. The known 15-lipoxygenase inhibitory activity data (IC50 of 19 polysulfides out of the whole data set were correlated in a multiple linear regression procedures with the computed descriptors. Statistically, the most significant overall correlations were five- and four- parameter equations with good statistical parameters; R2= 0.9981, R2CV = 0.9970 and R2=9967, R2CV = 0.9933 respectively. The models concluded that biological activity of polysulfides is mainly attributed to quantum-chemical, geometrical and topological descriptors with neither electrostatic contribution nor chief role of sulfur atoms. Also sulfur related descriptors were not the most significant contributors in the concluded models. The obtained models were efficiently employed to estimate the biological activities of the other 11 polysulfides available in natural products such as garlic and mushroom.

  8. Functional metabolomics reveals novel active products in the DHA metabolome

    Directory of Open Access Journals (Sweden)

    Masakazu eShinohara

    2012-04-01

    Full Text Available Endogenous mechanisms for successful resolution of an acute inflammatory response and the local return to homeostasis are of interest because excessive inflammation underlies many human diseases. In this review, we provide an update and overview of functional metabolomics that identified a new bioactive metabolome of docosahexaenoic acid (DHA. Systematic studies revealed that DHA was converted to DHEA-derived novel bioactive products as well as aspirin-triggered (AT forms of protectins. The new oxygenated DHEA derived products blocked PMN chemotaxis, reduced P-selectin expression and platelet-leukocyte adhesion, and showed organ protection in ischemia/reperfusion injury. These products activated cannabinoid receptor (CB2 receptor and not CB1 receptors. The AT-PD1 reduced neutrophil (PMN recruitment in murine peritonitis. With human cells, AT-PD1 decreased transendothelial PMN migration as well as enhanced efferocytosis of apoptotic human PMN by macrophages. The recent findings reviewed here indicate that DHEA oxidative metabolism and aspirin-triggered conversion of DHA produce potent novel molecules with anti-inflammatory and organ-protective properties, opening the DHA metabolome functional roles.

  9. Chocolate consumption, fecal water antioxidant activity, and hydroxyl radical production.

    Science.gov (United States)

    Record, Ian R; McInerney, Jennifer K; Noakes, Manny; Bird, Anthony R

    2003-01-01

    As part of a larger study into the effects of polyphenols derived from chocolate on bowel health we have compared the effects of consumption of chocolate containing either 200 mg of flavanols and related procyanidins or a similar chocolate containing less than 10 mg of polyphenols on fecal free radical production and antioxidant activity in 18 volunteers. In a double-blind crossover trail volunteers consumed chocolate for two 4-wk periods separated by a 4-wk washout period. During the time the volunteers consumed the chocolate they also consumed a low-polyphenol diet. Free radical production in the fecal water was lowered from 122 +/- 10 micromol/l/h to 94 +/- 9 micromol/l/h (P = 0.009) when the high procyanidin chocolate diet was consumed and from 117 +/- 14 micromol/l/h to 86 +/- 12 micromol/l/h when the low procyanidin chocolate was consumed (P = 0.014). Fecal water antioxidant capacity measured by either the Trolox equivalent antioxidant capacity or ferric reducing ability of plasma procedure was not significantly affected. Consumption of either chocolate reduced the production of free radicals in fecal water. This suggests that some component of the chocolate other than the flavanols and related procyanidins may have been effective.

  10. Sustainable production of biologically active molecules of marine based origin.

    Science.gov (United States)

    Murray, Patrick M; Moane, Siobhan; Collins, Catherine; Beletskaya, Tanya; Thomas, Olivier P; Duarte, Alysson W F; Nobre, Fernando S; Owoyemi, Ifeloju O; Pagnocca, Fernando C; Sette, L D; McHugh, Edward; Causse, Eric; Pérez-López, Paula; Feijoo, Gumersindo; Moreira, Ma T; Rubiolo, Juan; Leirós, Marta; Botana, Luis M; Pinteus, Susete; Alves, Celso; Horta, André; Pedrosa, Rui; Jeffryes, Clayton; Agathos, Spiros N; Allewaert, Celine; Verween, Annick; Vyverman, Wim; Laptev, Ivan; Sineoky, Sergei; Bisio, Angela; Manconi, Renata; Ledda, Fabio; Marchi, Mario; Pronzato, Roberto; Walsh, Daniel J

    2013-09-25

    The marine environment offers both economic and scientific potential which are relatively untapped from a biotechnological point of view. These environments whilst harsh are ironically fragile and dependent on a harmonious life form balance. Exploitation of natural resources by exhaustive wild harvesting has obvious negative environmental consequences. From a European industry perspective marine organisms are a largely underutilised resource. This is not due to lack of interest but due to a lack of choice the industry faces for cost competitive, sustainable and environmentally conscientious product alternatives. Knowledge of the biotechnological potential of marine organisms together with the development of sustainable systems for their cultivation, processing and utilisation are essential. In 2010, the European Commission recognised this need and funded a collaborative RTD/SME project under the Framework 7-Knowledge Based Bio-Economy (KBBE) Theme 2 Programme 'Sustainable culture of marine microorganisms, algae and/or invertebrates for high value added products'. The scope of that project entitled 'Sustainable Production of Biologically Active Molecules of Marine Based Origin' (BAMMBO) is outlined. Although the Union is a global leader in many technologies, it faces increasing competition from traditional rivals and emerging economies alike and must therefore improve its innovation performance. For this reason innovation is placed at the heart of a European Horizon 2020 Strategy wherein the challenge is to connect economic performance to eco performance. This article provides a synopsis of the research activities of the BAMMBO project as they fit within the wider scope of sustainable environmentally conscientious marine resource exploitation for high-value biomolecules. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. OSIRIS reactor radioprotection, radioprotection measurements performed during the power rise and the first 50 megawatt operation; Radioprotection de la pile OSIRIS, mesures de radioprotection effectuees au cours de la montee en puissance et des premiers fonctionnements a 50 megawatts

    Energy Technology Data Exchange (ETDEWEB)

    Fanton, B.; Lebouleux, P

    1967-12-01

    The authors supply the results of the measurements that have been made near the Osiris reactor during the power increase and during the first functioning at 50 megawatts. The measurements relate to the absorbed dose rates in the premises, the water activation and the atmospheric contamination. The influence of the heat layer of water movements and the water rate in the core chimney on the absorbed dose rate at the footbridge level overhanging the pile core has been studied. The modifications to the protection devices that have been proposed after the measurements and the effect of these modifications on the results of the measures are given then. The regeneration process of a water purification chain has been examined from the radiation protection point of view. It has been possible to make some twenty radionuclides obvious in the produced effluents and to determine the volume activity of these effluents for each radionuclide. The whole of results show that in a general way, the irradiation levels are low during the usual reactor functioning. [French] Les auteurs fournissent les resultats des mesures de radioprotection oui ont ete effectuees aupres de la pile Osiris pendant la montee en puissance et au cours des premiers fonctionnements a 50 megawatts. Les mesures portent sur les debits de dose absorbee dans les locaux, l'activation de l'eau et la contamination atmospherique. L'influence de la couche chaude des mouvements d'eau et du debit d'eau dans la cheminee du coeur sur le debit de dose absorbee au niveau de la passerelle surplombant le coeur de la pile, a ete etudiee. Les modifications aux dispositifs de protection, qui ont ete proposees a la suite des mesures, et l'effet de ces modifications sur les resultats des mesures sont indiques ensuite. Le processus de regeneration d'une chaine d'epuration de l'eau a ete examine sous l'angle de la radioprotection. Il a ete possible de mettre en evidence une vingtaine

  12. Mesure de la satisfaction des patients migrants en milieu hospitalier: analyse des lacunes existantes et recommandations

    OpenAIRE

    Stotzer, Urszula; Efionayi-Mäder, Denise; Wanner, Philippe

    2007-01-01

    L'étude porte sur les lacunes existantes en matière de mesure de la satisfaction des patients migrants en milieu hospitalier et formule des recommandations à l'adresse des établissements hospitaliers et autorités compétentes. Les résultats démontrent que les outils d'évaluation de la satisfaction des patients migrants comportent des problèmes liés à la fois à la procédure d'enquête et aux instruments, susceptibles de limiter la pertinence des résultats obtenus en vue de l'amélioration de la q...

  13. Un appareillage simple pour la mesure de la diffusivité thermique de plaques minces

    Science.gov (United States)

    Hadisaroyo, D.; Batsale, J. C.; Degiovanni, A.

    1992-01-01

    The aim of this work is to present a new method for the measurement of the thermal diffusivity of samples of low thickness (lower than 1mm). The unsteady one-dimensional heat transfer problem is considered in a straight fin using the Laplace transform for the time variable. Two temperature measurements are made versus time at two different absicas. It allows to set out two parameters: the characteristic time of the sample and the Biot number relative to the lateral heat exchange. The sensitivity of the parameters is studied and a domain of Laplace variable is determined for the identification. Ce travail propose une méthode originale de mesure de la diffusivité thermique de matériaux de faible épaisseur (inférieure à 1mm). L'équation de la chaleur est résolue en régime transitoire en utilisant les hypothèses de l'ailette et dans l'espace de Laplace. La mesure de température au cours du temps en deux points de l'échantillon permet de mettre en évidence deux paramètres : le temps caractéristique de l'échantillon et le nombre de Biot associé aux échanges. Une étude de sensibilité est effectuée et une méthode d'identification est déduite pour un certain domaine de la variable de Laplace. Un dispositif expérimental simple et une validation sont présentés dans le cas de matériaux métalliques. Une extension pour les isolants est en cours de montage.

  14. Capteurs monopodes pour mesures accélérométriques

    Science.gov (United States)

    Delaite, R.; Valentin, J.-P.

    1993-08-01

    A new design for accelerometric measurements sensors is described. It uses a plate vibrating in thickness shear mode, maintained by the means of a single holder located at the crystal edge. This mounting does cancel the mechanical and thermal stresses which generally modify the sensor output signal. So the ratio signal/noise of a thickness shear accelerometer is improved and the intrinsic sensitivity is multiplied by a factor 40, by comparison with the sensitivity of a thickness shear plate bonded by the means of two opposite holders. Un nouveau dispositif destiné aux mesures d'accélération est présenté. Il met en œuvre une lame vibrant en cisaillement d'épaisseur, fixée à sa structure de maintien par l'intermédiaire d'une unique liaison. Ce montage permet d'éliminer les contraintes mécaniques et thermiques qui perturbent habituellement le signal de mesure, et qui sont liées soit au montage des éléments du capteur, soit aux variations rapides de température qui interviennent lors de la mise en fonctionnement du capteur. Le rapport signal/bruit d'un accéléromètre à lame vibrant en cisaillement d'épaisseur s'en trouve amélioré et la sensibilité à l'accélération est multipliée par un facteur 40, comparée à celle d'un capteur qui serait constitué d'une lame vibrant en cisaillement d'épaisseur, fixée par deux liaisons diamétralement opposées.

  15. Study of the inclusive production of {phi}{sup 0} mesons and measurement of the branching ratio of the Z{sup 0} bosons into strange quarks pairs with the DELPHI detector at LEP; Etude de la production inclusive de mesons {phi}{sup 0} et mesure du rapport d`embranchement du boson Z{sup 0} en paires de quarks etranges aupres de l`experience DELPHI au LEP

    Energy Technology Data Exchange (ETDEWEB)

    Pages, P.

    1996-05-07

    The thesis work is relative to an analysis of data collected by the DELPHI detector at LET in 1992 and 1993, in order to study the inclusive production production of {phi}{sup 0} mesons, reconstructed according to the decay mode {phi}{sup 0} {yields} K{sup +}K{sup -}. The kaon identification, indispensable to do this reconstruction, was made by the Barrel RICH detector of DELPHI. This study was first done to test the {phi}{sup 0} production in the Lund string model, which is one of the models used to describe the production of hadrons in the e{sup +}e{sup -}processes. The experimental distribution of the differential cross section of the inclusive {phi}{sup 0} production was compared to the one predicted by the model and indicates that the model well reproduces the experimental data. The mean number of produced {phi}{sup 0} per hadronic event was found to be: 0.091 {+-} 0.013, in good agreement with the expected value: 0.091. Next, high momentum {phi}{sup 0} mesons were used for a measurement of the branching ratio of the Z{sup 0} bosons into strange quark pairs: {Gamma}{sub ss}-bar/{Gamma}{sub had}. Three {phi}{sup 0} mesons samples were selected, for which the purity in Z{sup 0}{yields} ss-bar events was greater than 60, 70 and 80 %. For each of these 3 samples, the obtained experimental values are respectively: 0.16 {+-} 0.04, 0.13{+-}0.04 et 0.12{+-}0.05. These values show relatively large uncertainties and indicate an agreement of at the most 2.6 standard deviations to the expected value: 0.22. (author). 63 refs.

  16. Distinct patterns of brain activity characterise lexical activation and competition in spoken word production.

    Directory of Open Access Journals (Sweden)

    Vitória Piai

    Full Text Available According to a prominent theory of language production, concepts activate multiple associated words in memory, which enter into competition for selection. However, only a few electrophysiological studies have identified brain responses reflecting competition. Here, we report a magnetoencephalography study in which the activation of competing words was manipulated by presenting pictures (e.g., dog with distractor words. The distractor and picture name were semantically related (cat, unrelated (pin, or identical (dog. Related distractors are stronger competitors to the picture name because they receive additional activation from the picture relative to other distractors. Picture naming times were longer with related than unrelated and identical distractors. Phase-locked and non-phase-locked activity were distinct but temporally related. Phase-locked activity in left temporal cortex, peaking at 400 ms, was larger on unrelated than related and identical trials, suggesting differential activation of alternative words by the picture-word stimuli. Non-phase-locked activity between roughly 350-650 ms (4-10 Hz in left superior frontal gyrus was larger on related than unrelated and identical trials, suggesting differential resolution of the competition among the alternatives, as reflected in the naming times. These findings characterise distinct patterns of activity associated with lexical activation and competition, supporting the theory that words are selected by competition.

  17. Production and biological activities of yellow pigments from Monascus fungi.

    Science.gov (United States)

    Chen, Gong; Wu, Zhenqiang

    2016-08-01

    Monascus yellow pigments (MYPs), are azaphilone compounds and one of the three main components of total Monascus pigments (MPs). Thirty-five hydrophilic or hydrophobic MYPs have been identified, with the majority being hydrophobic. Apart from screening special Monascus strains, some advanced approaches, such as extractive and high-cell-density fermentations, have been applied for developing or producing new MYPs, especially extracellular hydrophilic MYPs. The outstanding performance of MYPs in terms of resistance to photodegradation, as well as tolerance for temperature and pH, give natural MYPs reasonable prospects, compared with the orange and red MPs, for practical use in the present and future. Meanwhile, MYPs have shown promising potential for applications in the food and pharmaceutical industries based on their described bioactivities. This review briefly summarizes the reports to date on chemical structures, biological activities, biosynthetic pathways, production technologies, and physicochemical performances of MYPs. The existing problems for MYPs are discussed and research prospects proposed.

  18. Applications of bioassay for fission and activation products - Sept. 1980

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    This guide identifies the bases that will be used by the NRC staff in evaluating the need for license provisions to require bioassay programs in installations where employees may be subject to internal radiation exposure from the inhalation or ingestion of fission or neutron activation products. It also describes methods acceptable to the NRC staff for determining the persons to be included in a bioassay program, the sampling and measurement techniques to be used, the frequency of bioassay measurements to be made, actions to be taken based on designated levels of internal radioactivity, estimations of internal dose to be calculated from bioassay measurements, and record systems to be maintained appropriate to such bioassay programs

  19. World uranium exploration, resources, production and related activities

    International Nuclear Information System (INIS)

    Hanly, A.

    2014-01-01

    A Nuclear Energy Series publication entitled “World Uranium Exploration, Resources, Production and Related Activities” (WUERPRA) will soon be published by the IAEA. The objective of the publication is to provide a comprehensive compilation of historic uranium exploration, resources, production and related activities based primarily on information from the 1966 to 2009 editions of the publication “Uranium Resources, Production and Demand”, a joint publication of the International Atomic Energy Agency and the Nuclear Energy Agency/Organization for Economic Cooperation and Development commonly known as the ‘Red Book’. This has been supplemented by historic information from other reliable sources. The publications also include, where enough information was available, descriptions of the relative potential for discovery of new uranium resources on a per country basis. To recover complete historic information it is frequently necessary to refer to earlier editions of the Red Book, many of which may not be readily available. This publication aims to provide one comprehensive source for much of this type of information which will reduce the effort required to prepare future editions of the Red Book, as well as make the historic Red Book information, together with select related information from other sources, more readily available to all users with an interest in uranium. WUERPRA comprises 6 volumes containing 164 country reports, each organized by region; Volume 1: Africa (53 countries); Volume 2: Central, Eastern and Southeastern Europe (25 countries); Volume 3: Southeastern Asia, Pacific, East Asia (18 countries); Volume 4: Western Europe (22 countries); Volume 5: Middle East, Central and Southern Asia (19 countries), and; Volume 6: North America, Central America and South America (27 countries). The report also contains information on countries that have not reported to the Red Book. The poster will summarize select major highlights from each volume

  20. 78 FR 22843 - Foreign-Trade Zone 33-Pittsburgh, Pennsylvania, Authorization of Export Production Activity...

    Science.gov (United States)

    2013-04-17

    ..., Pennsylvania, Authorization of Export Production Activity, Tsudis Chocolate Company (Chocolate Confectionery Bars), Pittsburgh, Pennsylvania On December 4, 2012, Tsudis Chocolate Company, submitted a notification of proposed export production activity to the Foreign- Trade Zones (FTZ) Board for its facility...

  1. Measurements of gas and volatile element production rates from an irradiated molten lead and lead-bismuth spallation target with proton beams of 1 and 1.4 GeV; Mesures de taux de production d'elements gazeux et volatiles lors de reactions induites par des protons de 1 et 1,4 GeV sur des cibles epaisses de plomb et plomb-bismuth liquides

    Energy Technology Data Exchange (ETDEWEB)

    Tall, Y

    2008-03-15

    The integrated project EUROTRANS (European Research Programme for the Transmutation of High Level Nuclear Waste in an Accelerator Driven System) of the 6. EURATOM Framework Programme aims to demonstrate the transmutation of radioactive waste in ADS (Accelerator Driven Sub-critical system). It will carry out a first advanced design of an experimental facility to demonstrate the technical feasibility of transmutation, and will produce a conceptual design of an industrial facility dedicated to transmutation. An ADS consists of three fundamental elements: the accelerator of protons, the sub-critical core and the spallation target. SUBATECH (physique Sub-Atomique et des Technologies associees) laboratory is involved to the study of the chosen liquid lead-bismuth as a spallation ADS target. The irradiation of liquid lead-bismuth target with energetic proton beam generates in addition to neutrons, volatile and radioactive residues. In order to determine experimentally the production rates of gas and volatile elements following a spallation reaction in a lead-bismuth target, the experiment IS419 was performed at the ISOLDE facility at CERN (Centre Europeen de la Recherche Nucleaire). This experiment constitutes the frame of the thesis whose main objective is to assess and study the production and release rates of many gas and volatile element from the irradiated lead-bismuth target with an energetic proton beam. The obtained data are compared to Monte Carlo simulation code (MCNPX) results in order to test the intranuclear cascade model of Bertini and of Cugnon, and the evaporation options of Dresner and Schmidt. (author)

  2. Comparaison instrumentale de la mesure des précipitations en climat méditerranéen semi-aride

    OpenAIRE

    Brunel, Jean-Pierre

    1986-01-01

    La pluie est un élément important du cycle de l'eau mesuré à l'aide d'appareils très divers. A partir des données d'une station agrométéorologique du Nord de la Tunisie (zone semi-aride), il est montré dans quelles proportions peuvent varier les précipitations mesurées par différents capteurs. L'influence du vent est mise en évidence dans l'écart observé entre pluie mesurée au sol et pluie mesurée au-dessus du sol. (Résumé d'auteur)

  3. Measurement of the production cross-section of top quark pairs in the lepton+jets channel at D0 and ATLAS, and interpretation in terms of charged Higgs boson in ATLAS; Mesure de la section efficace de production de quarks top en paires dans le canal lepton+jets a D0 et a ATLAS et interpretation en terme de boson de Higgs charge dans ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Chevallier, F

    2007-05-15

    One of the main challenges of the current and future colliders TeVatron and LHC is the discovery of physics beyond the Standard Model. This goal may be accessible through precision measurements in the top quark sector. Deviations from theoretical predictions may bring to light the first indirect signs of new physics. The work exposed in this thesis deals with the production cross-section of top quark pairs via the strong interaction, within both D0 and ATLAS collaborations. Firstly, I have worked at D0 on the improvement of the reconstruction of soft electrons, in order to tag b-jets produced in top-anti top quarks events. Then I focused myself on the measurement of the top quark pair production cross-section with 420 pb{sup -1} of D0 data. The measured cross-section is in agreement with the Standard Model expectations. In the ATLAS experiment, I tried to develop a procedure in order to select top quark pair events, using the knowledge and the techniques from the D0 experiment. This work also high-lighted the main systematic sources that can affect the sensitivity of the measurement. After one year of data taking at low luminosity, this preliminary analysis obtains a sensitivity at a few percent level, leading to a good discovery potential of new physic signs, like charged Higgs bosons. These new particles appear in non minimal standard models, and modify the phenomenology of top pair events. This new analysis has shown a good sensitivity for some regions of the parameter space. (author)

  4. Production of biologically active recombinant human factor H in Physcomitrella.

    Science.gov (United States)

    Büttner-Mainik, Annette; Parsons, Juliana; Jérôme, Hanna; Hartmann, Andrea; Lamer, Stephanie; Schaaf, Andreas; Schlosser, Andreas; Zipfel, Peter F; Reski, Ralf; Decker, Eva L

    2011-04-01

    The human complement regulatory serum protein factor H (FH) is a promising future biopharmaceutical. Defects in the gene encoding FH are associated with human diseases like severe kidney and retinal disorders in the form of atypical haemolytic uremic syndrome (aHUS), membranoproliferative glomerulonephritis II (MPGN II) or age-related macular degeneration (AMD). There is a current need to apply intact full-length FH for the therapy of patients with congenital or acquired defects of this protein. Application of purified or recombinant FH (rFH) to these patients is an important and promising approach for the treatment of these diseases. However, neither protein purified from plasma of healthy individuals nor recombinant protein is currently available on the market. Here, we report the first stable expression of the full-length human FH cDNA and the subsequent production of this glycoprotein in a plant system. The moss Physcomitrella patens perfectly suits the requirements for the production of complex biopharmaceuticals as this eukaryotic system not only offers an outstanding genetical accessibility, but moreover, proteins can be produced safely in scalable photobioreactors without the need for animal-derived medium compounds. Transgenic moss lines were created, which express the human FH cDNA and target the recombinant protein to the culture supernatant via a moss-derived secretion signal. Correct processing of the signal peptide and integrity of the moss-produced rFH were verified via peptide mapping by mass spectrometry. Ultimately, we show that the rFH displays complement regulatory activity comparable to FH purified from plasma. © 2010 The Authors. Plant Biotechnology Journal © 2010 Society for Experimental Biology, Association of Applied Biologists and Blackwell Publishing Ltd.

  5. Evaluating Antimutagenic Activity of Probiotic Bacteria Isolated from Probiotic Products

    Directory of Open Access Journals (Sweden)

    R Kazemi Darsanki

    2012-07-01

    Full Text Available

    Background and Objectives: Probiotic bacteria are microbial nutrition supplements which have useful effects on human health by maintaining of bowel microbial balance. There are many studies that have been suggested the use of probiotic products as cancer risk reducer. The aim of this study, is isolation and detection of probiotic agents from yoghurt and probiotical tablet and evaluation of their abilities to decrease some effects of mutagenic and carcinogenic agents.

     

    Methods: In this study, probiotic bacteria were isolated from yogurt and probiotic tablet by using MRS in anaerobic condition (5% Co2 and gas peck and temperature of 37°c. Then, they were detected by using biochemical tests. Their anti mutagenic effects of supernatant culture were evaluated against mutagenic agents of azid Sodium and Potassium Permanganate by ames test (Salmonella typhimurium TA100 in presence and absence of S9.

     

    Results: Six probiotic bacteria were isolated from yogurt and probiotic tablet. Their anti mutagenic activity results based on ames test showed they can inhibit mutagenic agents more than 40% in some species, which is considered as a good result.

     

    Conclusion: The results of this study show that the use of probiotic bacteria found in different products such as yogurt and probiotic tablets, have proper anti mutagenic and anti carcinogenic effects. They change the micro flora of bowel and, as a result, reduce absorption of mutagenic and carcinogenic agents and help to maintain human health.

     

  6. Pipeline oil fire detection with MODIS active fire products

    Science.gov (United States)

    Ogungbuyi, M. G.; Martinez, P.; Eckardt, F. D.

    2017-12-01

    We investigate 85 129 MODIS satellite active fire events from 2007 to 2015 in the Niger Delta of Nigeria. The region is the oil base for Nigerian economy and the hub of oil exploration where oil facilities (i.e. flowlines, flow stations, trunklines, oil wells and oil fields) are domiciled, and from where crude oil and refined products are transported to different Nigerian locations through a network of pipeline systems. Pipeline and other oil facilities are consistently susceptible to oil leaks due to operational or maintenance error, and by acts of deliberate sabotage of the pipeline equipment which often result in explosions and fire outbreaks. We used ground oil spill reports obtained from the National Oil Spill Detection and Response Agency (NOSDRA) database (see www.oilspillmonitor.ng) to validate MODIS satellite data. NOSDRA database shows an estimate of 10 000 spill events from 2007 - 2015. The spill events were filtered to include largest spills by volume and events occurring only in the Niger Delta (i.e. 386 spills). By projecting both MODIS fire and spill as `input vector' layers with `Points' geometry, and the Nigerian pipeline networks as `from vector' layers with `LineString' geometry in a geographical information system, we extracted the nearest MODIS events (i.e. 2192) closed to the pipelines by 1000m distance in spatial vector analysis. The extraction process that defined the nearest distance to the pipelines is based on the global practices of the Right of Way (ROW) in pipeline management that earmarked 30m strip of land to the pipeline. The KML files of the extracted fires in a Google map validated their source origin to be from oil facilities. Land cover mapping confirmed fire anomalies. The aim of the study is to propose a near-real-time monitoring of spill events along pipeline routes using 250 m spatial resolution of MODIS active fire detection sensor when such spills are accompanied by fire events in the study location.

  7. Les fondements de la mesure du temps comment les fréquences atomiques règlent le monde

    CERN Document Server

    Audoin, Claude

    1998-01-01

    La mesure du temps fondée sur des propriétés atomiques est née en 1955, avec le premier étalon de fréquence à jet de césium. Depuis, les horloges atomiques ne cessent de progresser et sont au coeur de nombreuses activités, telles que les comparaisons de temps, l'unification mondiale de l'heure ou la recherche en astronomie, géodésie, géophysique, télécommunications, etc. Cet ouvrage fournira des réponses détaillées au lecteur intéressé par la mesure du temps appliquée aux divers domaines cités.

  8. Impurities in Drug Products and Active Pharmaceutical Ingredients.

    Science.gov (United States)

    Kątny, M; Frankowski, M

    2017-05-04

    Analytical methods should be selective and fast. In modern times, scientists strive to meet the criteria of green chemistry, so they choose analytical procedures that are as short as possible and use the least toxic solvents. It is quite obvious that the products intended for human consumption should be characterized as completely as possible. The safety of a drug is dependent mainly on the impurities that it contains. High pressure liquid chromatography and ultra-high pressure liquid chromatography have been proposed as the main techniques for forced degradation and impurity profiling. The aim of this article was to characterize the relevant classification of drug impurities and to review the methods of impurities determination for atorvastatin (ATV) and duloxetine (DLX) (both in active pharmaceutical ingredients and in different dosage forms). These drugs have an impact on two systems of the human body: cardiac and nervous. Simple characteristics of ATV and DLX, their properties and specificity of action on the human body, are also included in this review. The analyzed pharmaceuticals-ATV (brand name Lipiron) and DLX (brand name Cymbalta)-were selected for this study based on annual rankings prepared by Information Medical Statistics.

  9. Création d'outils pour la mesure de l'intégration des technologies de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Création d'outils pour la mesure de l'intégration des technologies de l'information et de la communication en éducation. Depuis quelques années, plusieurs ... Colombia, Mexico, Peru, Uruguay. Project Leader. Susana Martínez Restrepo. Institution. Fundación para la Educación Superior y el Desarrollo. Institution Country.

  10. Multi-criterial optimisation task of managing efficiency of production and economic activity of an enterprise

    OpenAIRE

    Malyarets Lyudmila M.; Senkevych Borys V.; Zhukov Andriy V.

    2013-01-01

    The article develops a multi-criterial optimisation task of managing efficiency of production and economic activity of an industrial enterprise. It justifies specification of the model of managing efficiency of production and economic activity of an industrial enterprise. In order to compose functions of a goal and partial criteria, it recommends to structure efficiency of production and economic activity of an enterprise by three components: efficiency of subsystems of production and economi...

  11. Smos Land Product Validation Activities at the Valencia Anchor Station

    Science.gov (United States)

    Lopez-Baeza, Ernesto

    ABSTRACT Soil moisture is a key parameter controlling the exchanges between the land surface and the atmosphere. In spite of being important for weather and climate modeling, this parameter is not well observed at a global scale. The SMOS (Soil Moisture and Ocean Salinity) Mission was designed by the European Space Agency (ESA) to measure soil moisture over continental surfaces as well as surface salinity over the oceans. Since 2001, the Valencia Anchor Station is currently being prepared for the validation of SMOS land products, namely soil moisture content and vegetation water content. The site has recently been selected by the Mission as a core validation site, mainly due to the reasonable homogeneous characteristics of the area which make it appropriate to undertake the validation of SMOS Level 2 land products during the Mission Commissioning Phase, before attempting more complex areas. Close to SMOS launch, ESA has defined and designed a SMOS V alidation Rehearsal C ampaign P lan which purpose is to repeat the Commissioning Phase execution with all centers, all tools, all participants, all structures, all data available, assuming all tools and structures are ready and trying to produce as close as possible the post-launch conditions. The aim is to test the readiness, the ensemble coordination and the speed of operations, and to avoid as far as possible any unexpected deficiencies of the plan and procedure during the real C ommissioning P hase campaigns. For the rehearsal activity, a control area of 10 x 10 km2 has been chosen at the Valencia Anchor Station study area where a network of ground soil moisture measuring stations is being set up based on the definition of homogeneous physio-hydrological units, attending to climatic, soil type, lithology, geology, elevation, slope and vegetation cover conditions. These stations are linked via a wireless communication system to a master post accessible via internet. The ground soil moisture stations will also be used

  12. A Study on Situated Cognition: Product Dissection's Effect on Redesign Activities

    Science.gov (United States)

    Grantham, Katie; Okudan Kremer, Gül E.; Simpson, Timothy W.; Ashour, Omar

    2013-01-01

    Situated cognition theory describes the context of a learning activity's effect on learner's cognition. In this paper, we use situated cognition theory to examine the effect of product dissection on product redesign activities. Two specific research questions are addressed: 1) Does situated cognition, in the form of product dissection, improve…

  13. Electromagnetic Isotope Separator: Magnetic Measurement: Results; Le separateur electromagnetique d'isotopes: mesures magnetiques: resultats

    Energy Technology Data Exchange (ETDEWEB)

    Boge, M.; Baud, A. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1968-07-01

    The electromagnetic isotope separator of the University of Grenoble can produce isotope with a great purity. It has two magnets with non homogeneous field. The magnetic fields have been corrected with shims in order to obtain an accuracy of {+-}10{sup -4} in the useful region. These shims have been determined experimentally by measurements. The great enrichment factors obtained, prove the quality of this apparatus. (author) [French] Le separateur electromagnetique d'isotopes de la Faculte des Sciences de Grenoble a prouve qu'il etait capable de produire des isotopes de grande purete. Ceci a ete rendu possible en grande partie grace a la qualite des deux electro-aimants identiques a champ inhomogene places en cascade. Les champs magnetiques ont ete corriges par des shims afin d'obtenir dans la zone utile de l'entrefer une precision de champ de l'ordre de {+-}10{sup -4}. Ces shims ont ete determines experimentalement par des mesures magnetiques tres precises. Les coefficients d'enrichissement eleves obtenus font de cet appareil un precieux outil de travail. (auteur)

  14. Design of Continuous Crystallizers for Production of Active Pharmaceutical Ingredients

    DEFF Research Database (Denmark)

    Capellades Mendez, Gerard; Christensen, Troels V.

    Manufacturing (CPM) could lead to significant reductions in the production costs and an improved consistency of the product quality. As a result, development of such processes has received a significant interest in the past decade. To be able to compete in a patent-driven industry with relatively small annual...... production rates, CPM should be conducted in versatile units that offer short process development times and can be used for production of different compounds. This PhD project deals with the development of novel crystallizer configurations and process design methods oriented to the crystallization of APIs...

  15. Applications of short-lived activation products in neutron activation analysis of bio-environmental specimens

    International Nuclear Information System (INIS)

    1987-03-01

    This report discusses the advantages and disadvantages, special techniques, and actual and potential applications of neutron activation analysis (NAA) utilizing short-lived neutron-induced products, with special reference to the analysis of samples of biological and environmental origin. Attention is devoted mainly to products having half-lives in roughly the range of 10 milliseconds to 60 seconds, but with some discussion of the usefulness of even shorter-lived species, and ones with half-lives as long as a few minutes. Important aspects of the analytical methodology include sample preparation, irradiation/transfer systems, activity measurements, data processing and analytical quality assurance. It is concluded that several trace elements can be determined in bio-environmental samples (as well as in samples of industrial, geochemical and other origin). In particular, this method provides analytical possibilities for several elements (e.g. B, F, Li and V) that are difficult to determine in some matrices at trace levels by any other technique. These conclusions are illustrated in an annex by results of calculations in which the applicability of the techniques to the analysis of several biological and environmental reference materials is evaluated by means of an advance computer prediction program. The report concludes with an annotated bibliography of relevant publications (including abstracts, where available) taken from the INIS database. (author)

  16. Propulsion and Energetics Panel Working Group 23 on Guide to the Measurement of the Transient Performance of Aircraft Turbine Engines and Components (Guide pour la mesure des performances en transitoire des turbomachines Aeronautiques et de leurs composants)

    Science.gov (United States)

    1994-03-01

    compression et du debit d’air au pompage, qui »rail d’un itaMl primordial pour la conception el le developpement de moteurs , et (ii) la mesure du temps ...compris de la vitesse de rotation el des tolerances, de la poussrfe, du couple et de I’utilisation du systime de cummande moteur pour la mesure...des procedures d’estimatmn d’incenitude des mesures tramiloircs. II se teranine par une etude deuiltee dc deux exemples; (i;) la mesure du taux de

  17. Interacting temperature and water activity modulate production of ...

    African Journals Online (AJOL)

    West African Journal of Applied Ecology ... Concentrations of DA were further modulated by interactions of temperature and aw. ... was at 0.98 aw and 35°C while the lowest was at 0.96 aw and 35°C. The abiotic interactions that supported biomass production appeared different from what was required for production of DA.

  18. High Activity catalysts for Polyols Production From C-6 Sugars

    Energy Technology Data Exchange (ETDEWEB)

    Todd Werpy; Alan Zacher; John Frye; Keith Peterson; Gary Neuenschwander; Eric Alderson; Daniel Muzatko; Jim White

    2003-05-06

    Over the course of this project, many significant discoveries have been made in the process for the conversion of sorbitol to value added products. The object was developing a process for the production of propylene glycol (PG), ethylene glycol (EG), and glycerol from sorbitol.

  19. VIIRS 375m, I-Band Active Fire Product NRT (Vector Data)

    Data.gov (United States)

    National Aeronautics and Space Administration — The VIIRS 375m active fire product is the latest product to be added to FIRMS. It provides data from the Visible Infrared Imaging Radiometer Suite (VIIRS) sensor...

  20. Production and characterization of activated carbon from a ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-10-20

    Oct 20, 2008 ... Key words: Activated carbons, activation, BET surface area, Fourier Transmittance Infrared Spectroscopy. (FTIR). INTRODUCTION. Activated carbon can be defined as carbonaceous material having high porosity and internal surface area and cannot be characterized by any distinctive chemical formula.

  1. Cyclic changes of steroid production activity in the ovary and ...

    African Journals Online (AJOL)

    1986-07-25

    Jul 25, 1986 ... cells and estradiol-17~ concentration in the plasma reached a peak during exogenous vitellogenesis. .... 3~-HSD activity; ><205. 3(3-Hydroxy steroid dehydrogenase (3~-HSD) activity in the adrenal gland of the rat. B. Activity 1 (Act: 1) x205. Interstitial cells ([SC); special Iheca cells (STC); Stage ITT oocyte ...

  2. Short-lived radionuclide production activities in continental Europe

    International Nuclear Information System (INIS)

    Helus, F.

    1985-01-01

    This paper summarizes the information about the production of short-lived radionuclides on medical cyclotrons in the European area. The author focuses on the production of some specific radionuclides that are made for the preparation of radiopharmaceuticals for medical, diagnostic, and tracer studies. The author has chosen to comment on those few short-lived radionuclides that are currently in demand on a regular basis, e.g., 123 I and 81 Rb and the neutron-deficient positron-emitting radionuclides 11 C, 13 N, and 15 O. The isotope-production data and rates mentioned are based on information requested from more than 50 European cyclotron laboratories

  3. Les principes distributifs des mesures d’insertion des jeunes à l’épreuve du longitudinal Youth integration measures and their criteria tested by a longitudinal approach

    Directory of Open Access Journals (Sweden)

    Léa Lima

    2009-07-01

    Full Text Available La sélection des bénéficiaires des mesures d’action sociale relève d’un problème éthique qui fait l’objet d’une intense activité cognitive et normative de la part d’acteurs publics outillés par l’expertise. Or, l’examen historique des principes distributifs mobilisés dans les politiques d’insertion des jeunes donne à voir la reformulation des référentiels de l’action publique dans un cadre longitudinal ainsi que ses effets sur les présupposés éthiques des politiques. Le principe de discrimination positive consistant à redistribuer les chances d’insertion en faveur des jeunes les moins formés a été énoncé au sein d’une représentation instantanéiste de l’insertion des jeunes. Il perd de sa validité avec l’institutionnalisation des trajectoires. L’éthique de l’accompagnement du parcours qui devient dominante dans les années 1990 perd de vue les inégalités entre groupes de niveau de formation au profit d’une démarche d’organisation de carrières ascendantes permises par les mesures d’action sociale disponibles.Targeting social programs is an ethical problem for administrators. Therefore, they develop an intense cognitive and normative activity with the help of experts in economics. The history of how funds are allocated in support of youth integration policies shows the longitudinal reframing of public policy and its impact on ethical principles. The principle of affirmative action consisting in redistributing offers among less qualified youth has been formulated according to a static representation of youth integration. It loses its validity with the institutionalization of individual itineraries. The ethic of pathway support that became dominant in the 1990s lost sight of the inequality between groups levels of qualification no longer appeared relevant and gave way to the organization of upwardly mobile careers made possible by the social programs at hand.

  4. Production of activated carbon from acorns and olive seeds

    Energy Technology Data Exchange (ETDEWEB)

    Lafi, W.K. [Amman College for Engineering Technology, Marka (Jordan)

    2001-07-01

    This study has been designed to produce activated carbon from acorns and olive seeds. The starting materials are low in cost and they are the cause of solid waste pollution problems in Jordan. A chemical procedure is used to produce the required activated carbon. The results indicate that activated carbon produced from acorns compares favourably with that from olive seeds which rank second, along side commercial type activated carbon which comes last with respect to adsorption capacity. However, the optimum activated temperature is 800 {sup o}C and the optimum regeneration temperature is also 800 {sup o}C. (Author)

  5. Effect of Celebrity Endorsement in Advertising Activities by Product Type

    Directory of Open Access Journals (Sweden)

    Karasiewicz Grzegorz

    2014-12-01

    Full Text Available This article seeks to answer two related questions: are celebrity endorsements more likely to be result in a higher evaluation of the product being advertised than use of an anonymous individual (e.g. a typical consumer; and, if present, do these positive effects vary by product category? To answer these two questions research was conducted on a 237 student sample employing a quasi-experiment consisting of four groups (two product categories and two types of endorsers using data collected through an online survey. The results indicate that celebrity endorsements do have a positive impact on the evaluation of durable goods, but do not affect the evaluation of frequently purchased products. This finding largely confirms the assumptions of the match-up model, the meaning transfer model, and the ELM model.

  6. Activity of disinfectants and biofilm production of Corynebacterium pseudotuberculosis

    OpenAIRE

    Sá, Maria da C.A.; Veschi, Josir L.A.; Santos, Grace B.; Amanso, Evandro S.; Oliveira, Samily A.S.; Mota, Rinaldo A.; Veneroni-Gouveia, Gisele; Costa, Mateus M.

    2013-01-01

    To verify the occurrence of caseous lymphadenitis in sheep and goats on farms of Pernambuco, Brazil, and in animals slaughtered in two Brazilian cities (Petrolina/PE and Juazeiro/BA), and to characterize the susceptibility profile of Corynebacterium pseudotuberculosis to disinfectants and antimicrobials, and its relationship with biofilm production were the objectives of this study. 398 samples were tested for sensitivity to antimicrobial drugs, disinfectants, and biofilm production. Among th...

  7. Competivity and management activities in die production systems

    Directory of Open Access Journals (Sweden)

    Mariana Rasina

    2010-12-01

    Full Text Available Currently for a production system to act on a global market must have a policy-oriented performance management to increase competitiveness. Performance management should be focused on improved performance by operating rules and principles, techniques, operating methods and tools for improving business performance. To track progress of production, performances should be a system of indicators, well made and systematically followed up.

  8. 78 FR 41911 - Foreign-Trade Zone 161-Sedgwick County, Kansas; Authorization of Production Activity; Siemens...

    Science.gov (United States)

    2013-07-12

    ... Activity; Siemens Energy, Inc. (Wind Turbine Nacelles and Hubs); Hutchinson, Kansas On March 7, 2013, Siemens Energy, Inc., an operator of FTZ 161, submitted a notification of proposed production activity to...

  9. Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis.

    Science.gov (United States)

    Crane, Erika A; Gademann, Karl

    2016-03-14

    Natural products have had an immense influence on science and have directly led to the introduction of many drugs. Organic chemistry, and its unique ability to tailor natural products through synthesis, provides an extraordinary approach to unlock the full potential of natural products. In this Review, an approach based on natural product derived fragments is presented that can successfully address some of the current challenges in drug discovery. These fragments often display significantly reduced molecular weights, reduced structural complexity, a reduced number of synthetic steps, while retaining or even improving key biological parameters such as potency or selectivity. Examples from various stages of the drug development process up to the clinic are presented. In addition, this process can be leveraged by recent developments such as genome mining, antibody-drug conjugates, and computational approaches. All these concepts have the potential to identify the next generation of drug candidates inspired by natural products. © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  10. Mesure de haute resolution de la fonction de distribution radiale du silicium amorphe pur

    Science.gov (United States)

    Laaziri, Khalid

    1999-11-01

    Cette these porte sur l'etude de la structure du silicium amorphe prepare par irradiation ionique. Elle presente des mesures de diffraction de rayons X sur de la poudre de silicium cristallin, du silicium amorphe relaxe et non relaxe, ainsi que tous les developpements mathematiques et physiques necessaires pour extraire la fonction de distribution radiale correspondant a chaque echantillon. Au Chapitre I, nous presentons une methode de fabrication de membranes minces de silicium amorphe pur. Il y a deux etapes majeures lors du processus de fabrication: l'implantation ionique, afin de creer une couche amorphe de plusieurs microns et l'attaque chimique, pour enlever le reste du materiau cristallin. Nous avons caracterise premierement les membranes de silicium amorphe par spectroscopie Raman pour verifier qu'il ne reste plus de trace de materiau cristallin dans les films amorphes. Une deuxieme caracterisation par detection de recul elastique (ERD-TOF) sur ces memes membranes a montre qu'il y a moins de 0.1% atomique de contaminants tels que l'oxygene, le carbone, et l'hydrogene. Au Chapitre II, nous proposons une nouvelle methode de correction de la contribution inelastique "Compton" des spectres de diffusion totale afin d'extraire les pics de diffusion elastique, responsable de la diffraction de Bragg. L'article presente tout d'abord une description simplifiee d'une theorie sur la diffusion inelastique dite "Impulse Approximation" (IA) qui permet de calculer des profils de Compton en fonction de l'energie et de l'angle de diffusion 2theta. Ces profils sont utilises comme fonction de lissage de la diffusion Compton experimentale. Pour lisser les pics de diffusion elastique, nous avons utilise une fonction pic de nature asymetrique. Aux Chapitre III, nous exposons de maniere detaillee les resultats des experiences de diffraction de rayons X sur les membranes de silicium amorphe et la poudre de silicium cristallin que nous avons preparees. Nous abordons aussi les

  11. Using waste of Tofu production improved antagonistic activities of a ...

    African Journals Online (AJOL)

    Mrs. Hoa

    2012-10-04

    Oct 4, 2012 ... screened for their antagonistic activity against 10 races of Xoo causing rice bacterial blight disease. Three actinomycete strains ... antagonistic activity of VN10-A-44 against the Xoo pathogen and to make use of tofu waste for large- ..... vitamins and some essential amino acids which are very important for ...

  12. Production and characterization of activated carbon from leather ...

    African Journals Online (AJOL)

    Powdered activated carbon (PAC) was prepared from leather buffing waste, sawdust and lignite by carbonization at temperatures between 500 – 800oC followed by steam activation. Experimental results reveal a general decrease in yield of carbon residue with increase in temperature of carbonization. Samples of lignite ...

  13. Production of isomers by the cyclic activation method

    International Nuclear Information System (INIS)

    Salaita, G.N.; Eapen, P.K.

    1974-01-01

    The isomeric states formation cross sections for 14.8 MeV neutron reactions in Mg, Al, As, Y, In, Hf, Tl, Pb, and Bi were measured using the cyclic activation technique and a high resolution Ge(Li) detector. Isomeric activities originating from the various isotopes of lead and thallium were separated by proper choice of cyclic timing parameters and energy discrimination. Long lived isomeric and ground state activities were investigated through conventional activation method. The isomeric cross section ratios, sigma/sub m//sigma/sub g/ for six elements, were measured and compared to the theoretical predictions of the Huizenga-Vandenbosch method. The half-lives of short-lived activities were determined using a wide range time-to-pulse height converter and a multi-channel analyzer

  14. Amélioration des propriétés de mesure d'un questionnaire de satisfaction des patients hospitalisés : application d'un modèle de mesure à variable latente centrale

    OpenAIRE

    Tricaud-Vialle, Sophie; Morineau, Alain

    2010-01-01

    International audience; Les modèles d'équations structurelles peuvent être utilisés pour valider questionnaires et indicateurs de satisfaction. Les modèles de mesure de la satisfaction ont très souvent la particularité de présenter, parmi les variables latentes, une variable privilégiée qui constitue le centre du modèle : cette variable latente, la satisfaction, est la variable endogène d'une équation dont toutes les autres latentes sont les variables exogènes. Ces autres variables latentes s...

  15. Interacting Temperature and Water Activity Modulate Production of ...

    African Journals Online (AJOL)

    Online2PDF.com

    Concentrations of DA were further modulated by interactions of temperature and aw. The retention time for DA in the ... was at 0.96 aw and 35°C. The abiotic interactions that supported biomass production appeared different from what was required for ... West African Journal of Applied Ecology, vol. 24(1), 2016: 31–42.

  16. Production of microbial glycolipid biosurfactants and their antimicrobial activity

    Science.gov (United States)

    Microbial glycolipids produced by bacteria or yeast as secondary metabolites, such as sophorolipids (SLs), rhamnolipids (RLs) and mannosylerythritol lipids (MELs) are “green” biosurfactants desirable in a bioeconomy. High cost of production is a major hurdle toward widespread commercial use of bios...

  17. Active Learning and Reflection in Product Development Engineering Education

    Science.gov (United States)

    Shekar, Aruna

    2007-01-01

    Traditional engineering courses at tertiary level have been traditionally theory-based, supported by laboratory work, but there is now a world-wide trend towards project-based learning. In product development education, project-based learning is essential in order to integrate the disciplines of design, marketing and manufacturing towards the…

  18. 78 FR 54449 - Subzone 8I, Authorization of Production Activity, Whirlpool Corporation (Washing Machines); Clyde...

    Science.gov (United States)

    2013-09-04

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-43-2013] Subzone 8I, Authorization of Production Activity, Whirlpool Corporation (Washing Machines); Clyde and Green Springs, Ohio On May 1, 2013, Whirlpool Corporation (Whirlpool) submitted a notification of proposed production activity to the Foreign...

  19. 78 FR 68814 - Subzone 183B; Authorization of Production Activity; Samsung Austin Semiconductor, LLC...

    Science.gov (United States)

    2013-11-15

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-70-2013] Subzone 183B; Authorization of Production Activity; Samsung Austin Semiconductor, LLC (Semiconductors); Austin, Texas On June 26, 2013, Samsung Austin Semiconductor, LLC submitted a notification of proposed export production activity to the...

  20. 77 FR 74170 - Authorization of Production Activity, Foreign-Trade Subzone 107A, Winnebago Industries, Inc...

    Science.gov (United States)

    2012-12-13

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-65-2012] Authorization of Production Activity, Foreign-Trade Subzone 107A, Winnebago Industries, Inc. (Polyurethane Coated Upholstery Fabric), Forest... Forest City and Charles City, Iowa, submitted a notification of proposed production activity to the...

  1. 21 CFR 357.810 - Active ingredients for deodorant drug products for internal use.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Active ingredients for deodorant drug products for internal use. 357.810 Section 357.810 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... HUMAN USE Deodorant Drug Products for Internal Use § 357.810 Active ingredients for deodorant drug...

  2. 77 FR 72816 - Foreign-Trade Zone 20-Suffolk, VA; Authorization of Production Activity; Usui International...

    Science.gov (United States)

    2012-12-06

    ... Foreign-Trade Zones Board Foreign-Trade Zone 20--Suffolk, VA; Authorization of Production Activity; Usui International Corporation (Diesel Engine Fuel Lines); Chesapeake, VA On June 28, 2012, the Virginia Port Authority, grantee of FTZ 20, submitted a notification of proposed production activity to the Foreign-Trade...

  3. Methodological approach to assessment of organizational resources of the productive activity

    Directory of Open Access Journals (Sweden)

    Alexander Miller

    2017-05-01

    Full Text Available The purpose of this article is to solve the problem connected with development of theoretical and methodological provisions of formation of the assessment procedure of organizational resources of the productive activity. Theoretical results of our research are: improvement of the concept of development of organizational resources of the productive activity; identifying the impact of organizational resources on the productive activity; justification of the basic principles of formation of the assessment system of efficiency of the organizational resources' use. We proposed a unified methodological approach allowing to combine the complexity of assessment of both quantity of core resources of the productive activity and organizational resources, which significantly develops traditional systems of the productive activity management based on identifying quantitative parameters of the subsystems, their assessment, comparison and analysis. We also substantiated our opinion on assessment of organizational resources' values. It is focused on the development of the productive activity and allows to use the developed tools of the methodological approach for forecast assessment of the impact of the quantity of core resources, used in the productive activity, and organizational resources of the productive activity on the economic results of the enterprise.

  4. Analysis of table egg production as a livelihood activity in Ekiti state ...

    African Journals Online (AJOL)

    This paper examines table egg production, as a livelihood activity in Ekiti Stat, Nigeriae Table egg production needs to be economically analyzed to determine its profitability. To be able to achieve this, variables such as socio-economics characteristics of the producers, cost and returns of table egg activity, constraints of ...

  5. Renforcer la résilience grâce à des mesures de lutte contre les ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    23 mars 2018 ... Une femme vérifiant son téléphone. Photo: Berhane Gebru. Deux étapes d'un projet réalisé en Afrique de l'Est axé sur ... Pour contribuer à la mise en œuvre de l'Accord de Paris, le Centre a notamment lancé un nouvel appel de propositions. Le projet Accélérer les mesures de lutte contre les changements ...

  6. L'état de l'environnement industriel français est-il objectivement mesurable ?

    OpenAIRE

    Gotteland, David; Boulé, Jean-Marie

    2004-01-01

    Working paper serie RMT (WPS 04-07); the environmental state is a frequently modelized variable in marketing research. This paper proposes updated scales and panorama of the objective state of 58 industrial branches defined by INSEE based on three characteristic dimensions: dynamism, complexity and capacity.; l'état de l'environnement est une variable fréquemment modélisée dans la recherche en marketing. A partir de ce constat, cet article propose une échelle de mesure et un panorama actualis...

  7. Nouvelles techniques de mesure des pluies, des débits liquides et solides sur parcelles agronomiques

    OpenAIRE

    Lamachère, Jean-Marie; Séguis, Luc

    1997-01-01

    Deux techniques différentes de mesure des pluies, des débits liquides et solides sur parcelles agronomiques sont présentés dans cet article. Le premier exemple correspond aux protocoles d'observations mis au point sur les grandes parcelles agronomiques (4 000 m2) de la région de Bidi, au nord-ouest du Burkina Faso. Ces protocoles s'appuient à la fois sur des observations directes, des prélèvements manuels et des enregistrements sur appareils mécaniques de précision. Les précisions obtenues su...

  8. Targeting and timing promotional activities : An agent-based model for the takeoff of new products

    NARCIS (Netherlands)

    Delre, S. A.; Jager, W.; Bijmolt, T. H. A.; Janssen, M. A.

    Many marketing efforts focus on promotional activities that support the launch of new products. Promotional strategies may play a crucial role in the early stages of the product life cycle, and determine to a large extent the diffusion of a new product. This paper proposes an agent-based model to

  9. Incremental product development : four essays on activities, resources, and actors

    OpenAIRE

    Olsen, Nina Veflen

    2006-01-01

    Most innovations are incremental, and incremental innovations play an important role for the firm. In spite of that, traditional NPD studies most often emphasize moderate to highly innovative product development projects. In this dissertation the overall objective is to increase our understanding of incremental innovation. The dissertation is organized around four essays that emphasize different aspects of incremental innovation. NPD in hotels, retailers and food manufact...

  10. Production of activated carbon from cellulosic fibers for environment protection

    International Nuclear Information System (INIS)

    Le Coq, L.; Faur, C.; Le Cloirec, P.; Phan Ngoc, H.

    2005-01-01

    Activated carbon fibers (ACF) have received an increasing attention in recent years as an adsorbent for purifying polluted gaseous and aqueous streams. Their preparation, characterization and application have been reported in many studies [1], which show that the porosity of ACF is dependent on activation conditions, as temperature, time or gas. ACF provide adsorption rates 2 to 50 times higher than Granular Activated Carbon [2], because of their low diameter (∼10 m) providing a larger external surface area in contact with the fluid compared with that of granules. Furthermore, their potential for the removal of various pollutants from water was demonstrated towards micro-organics like phenols [3], pesticides or dyes [4]. Generally, fibrous activated carbons are produced from natural or synthetic precursors by carbonization at 600-1000 C followed by an activation step by CO 2 oe steam at higher temperature [2]. Another way to produce the fibrous activated carbons is chemical activation with H 3 PO 4 , HNO 3 , KOH...[5]. Different types of synthetic or natural fibers have been used as precursors of fibrous activated carbons since 1970: polyacrylonitrile (PAN), polyphenol, rayon, cellulose phosphate, pitch, etc. Each of them has its own applications and limitations. The synthetic fibers being generally expensive, it would be interesting to find out low-cost precursors from local material resources. This work is a part of a research exchange program between the Vietnamese National Center of Natural Sciences and Technology (Vietnam) and the Ecole des Mines de Nantes (Gepea, France), with the aim to find some economical solutions for water treatment. Fibrous activated carbons are produced from natural cellulose fibers, namely jute and coconut fibers, which are abundant in Vietnam as well as in other tropical countries, have a low ash content and a low cost in comparison with synthetic fibers. Two methods are compared to produce activated carbons: 1) a physical

  11. Active Shop Scheduling Of Production Process Based On RFID Technology

    Directory of Open Access Journals (Sweden)

    Cuihua Chao

    2016-01-01

    Full Text Available In industry 4.0 environment, intelligent technology is almost applied to all parts of the manufacturing process, such as process design, job shop scheduling, etc.. This paper presents an efficient approach to job shop scheduling actively by using RFID to collect real-time manufacturing data. Identified the workpiece by RFID which needs to be machined, it can “ask for” the resource actively for the following process. With these active asking-for strategy, a double genetically encoded improved genetic algorithm is proposed for achieving active job shop scheduling solution during the actual manufacturing process. A case was used to evaluate its effectiveness. Meanwhile, , it can effectively and actively carry out job shop scheduling and has much better convergence effect comparing with basic genetic algorithm. And the job shop scheduler in management center can use the proposed algorithm to get the satisfied scheduling result timely by reducing waiting time and making begin time earlier during transmission between manufacturing process, which makes the scheduling result feasible and accurate.

  12. The influence of business strategy on new product activity : the mediating role of market orientation

    OpenAIRE

    Frambach, Ruud T.; Prabhu, Jaideep; Verhallen, Theo M.M.

    2000-01-01

    In this paper we examine how business strategy influences the nature and extent of firms’ market orientation and how this in turn influences the extent of firms’ new product activity. Specifically, we develop a framework linking firms’ relative emphasis on cost leadership, product differentiation and focus strategies on firms’ customer, competitor and supplier orientation as well as their new product development and introduction activity. We use this framework to develop relevant hypotheses w...

  13. Research and Production Corporation Radiy activities within Canadian nuclear market

    International Nuclear Information System (INIS)

    Bakhmach, I.; Siora, O.; Kharchenko, V.; Sklyar, V.; Andrashov, A.

    2011-01-01

    This paper presents key results of RPC Radiy activities within Canadian nuclear market. RPC Radiy (located in Kirovograd, Ukraine) is a vendor which designs and produces digital safety I and C platform as well as turnkey applications, based on the platform, for NPPs (safety systems). The main feature of the Radiy Platform is the application of Field Programmable Gates Arrays (FPGA) as programmable components for logic control operations. Since 2009 RPC Radiy started to explore the possibility to conduct the expansion to Canadian nuclear market. The activities performed by RPC Radiy related to this direction are resulted in several joint projects with Canadian companies. (author)

  14. Exploration and production activities and market - Panorama 2008; Activites et marches en exploration-production - Panorama 2008

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Following two banner years for the oil service and supply sector, marked by strong activity and a substantial increase in prices, the Exploration and Production market continued at a frenetic pace in 2007, although certain local markets retreated. In 2008, activity should stay high and prices should start stabilizing. With services in short supply, companies in the sector have been able to shift the balance of power with oil firms in their favor.

  15. Production of multiple extracellular enzyme activities by novel submerged culture of Aspergillus kawachii for ethanol production from raw cassava flour.

    Science.gov (United States)

    Sugimoto, Toshikazu; Makita, Tomohiro; Watanabe, Koutaro; Shoji, Hiroshi

    2012-04-01

    Cassava is a starch-containing root crop that is widely used as a raw material in a variety of industrial applications, most recently in the production of fuel ethanol. In the present study, ethanol production from raw (uncooked) cassava flour by simultaneous saccharification and fermentation (SSF) using a preparation consisting of multiple enzyme activities from Aspergillus kawachii FS005 was investigated. The multi-activity preparation was obtained from a novel submerged fermentation broth of A. kawachii FS005 grown on unmilled crude barley as a carbon source. The preparation was found to consist of glucoamylase, acid-stable α-amylase, acid carboxypeptidase, acid protease, cellulase and xylanase activities, and exhibited glucose and free amino nitrogen (FAN) production rates of 37.7 and 118.7 mg/l/h, respectively, during A. kawachii FS005-mediated saccharification of uncooked raw cassava flour. Ethanol production from 18.2% (w/v) dry uncooked solids of raw cassava flour by SSF with the multi-activity enzyme preparation yielded 9.0% (v/v) of ethanol and 92.3% fermentation efficiency. A feasibility study for ethanol production by SSF with a two-step mash using raw cassava flour and the multi-activity enzyme preparation manufactured on-site was verified on a pilot plant scale. The enzyme preparation obtained from the A. kawachii FS005 culture broth exhibited glucose and FAN production rates of 41.1 and 135.5 mg/l/h, respectively. SSF performed in a mash volume of about 1,612 l containing 20.6% (w/v) dry raw cassava solids and 106 l of on-site manufactured A. kawachii FS005 culture broth yielded 10.3% (v/v) ethanol and a fermentation efficiency of 92.7%.

  16. Production and characterization of activated carbon from wood wastes

    Science.gov (United States)

    Ramirez, A. P.; Giraldo, S.; Ulloa, M.; Flórez, E.; Y Acelas, N.

    2017-12-01

    Cedarwood (Cedrela Angustifolia) and teak (Tectona Grandis) woods are typically used for furniture manufacture because they have high durability, are light and easy to work. During these manufacturing process, large amount of these wastes is generated causing disposal environmental problems. In this paper, the residual wastes (sawdust) of Cedar (C) and Teak (T) are transformed into an activated material. The chemical composition of both biomass (C and T) was determinate by TGA (Thermogravimetric Analysis). Activated materials were characterized in surface area following the BET (Brunauer, Emmett and Teller) method, morphology using SEM (Scanning Electron Microscopy) and to know their functional groups a FTIR (Fourier Transform Infrared Spectroscopy) analysis was done. Their adsorption capacity was evaluated by removal of Methylene Blue (MB) and Congo Red (CR) from aqueous solutions.

  17. Special equipment for processing can-rupture measurements; Equipement specialise de traitement des mesures de rupture de gaines

    Energy Technology Data Exchange (ETDEWEB)

    Kaiser, J.; Phalippou, J.; Dumont, D.; Viellard, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    Recent installations for detecting can-rupture in nuclear reactors use, in the measurement processing section, a digital computer, either completely or partially. The reliability of the system is limited by that of the computer, which represents a common point for the processing of data from the detector. In order to satisfy the demands imposed by safety considerations for the operation of the equipment it is necessary to consider the possibility of installing a second computer in certain cases. The use of a computer involves the presence as interface between the detection equipment and the computer itself, of sealers operating as integrators for the pulses produced by the detector. By adding a certain number of circuits to these sealers, it is possible to carry out the work now demanded of the computer, as far as the calculation is concerned. This reasoning has led us to a so-called 'decentralized' solution involving the construction of specialized equipment in the region of the prospector itself. We believe that this solution, apart from the reliability point of view, has definite economic advantages. In our solution, the common point in the processing of the data is now situated not in the zone of the production of results but further down, in the printing out of these results. Even in the case of an incident at the common point, the results are produced, exposed and compared to the alarm thresholds. In the case of a breakdown of the specialized equipment, the results from this prospector are no longer available but the others continue to operate. It seems that this solution is more reliable than that employing universal computers. By using an interchangeable drawer system (MULTIBLOC) it is possible to replace rapidly any of the specialized equipment which breaks down. The systematic use of integrated circuits (TTL) ensures an increased reliability of the equipment. (author) [French] Les installations recentes de detection de rupture de gaines

  18. Enhancing efficiency of production cost on seafood process with activity based management method

    Science.gov (United States)

    Tarigan, U.; Tarigan, U. P. P.

    2018-02-01

    The efficiency of production costs has an important impact maintaining company presence in the business world, as well as in the face of increasingly sharp global competition. It was done by identifying and reducing non-value-added activities to decrease production costs and increase profits. The study was conducted at a company engaged in the production of squid (seafood). It has a higher product price than the market as Rp 50,000 per kg while the market price of squid is only Rp 35,000 per kg. The price of the product to be more expensive compared with market price, and thereby a lot more consumers choose the lower market price. Based on the discussions conducted, the implementation of Activity Based Management was seen in the reduction of activities that are not added value in the production process. Since each activities consumers cost, the reduction of nonvalue-added activities has effects on the decline of production cost. The production’s decline costs mainly occur in the reduction of material transfer costs. The results showed that there was an increase after the improvement of 2.60%. Increased production cost efficiency causes decreased production costs and increased profits.

  19. Activity of disinfectants and biofilm production of Corynebacterium pseudotuberculosis

    Directory of Open Access Journals (Sweden)

    Maria da C.A. Sá

    2013-11-01

    Full Text Available To verify the occurrence of caseous lymphadenitis in sheep and goats on farms of Pernambuco, Brazil, and in animals slaughtered in two Brazilian cities (Petrolina/PE and Juazeiro/BA, and to characterize the susceptibility profile of Corynebacterium pseudotuberculosis to disinfectants and antimicrobials, and its relationship with biofilm production were the objectives of this study. 398 samples were tested for sensitivity to antimicrobial drugs, disinfectants, and biofilm production. Among the 108 samples collected on the properties, 75% were positive for C. pseudotuberculosis. Slaughterhouse samples indicated an occurrence of caseous lymphadenitis in 15.66% and 6.31% for animals slaughtered in Petrolina and Juazeiro respectively. With respect to antimicrobials, the sensitivity obtained was 100% for florfenicol and tetracycline; 99.25% for enrofloxacin, ciprofloxacin and lincomycin; 98.99% for cephalothin; 98.74% for norfloxacin and sulfazotrim; 97.74% for gentamicin; 94.22% for ampicillin; 91.71% for amoxicillin; 91.21% for penicillin G; 89.19% for neomycin and 0% for novobiocin. In analyzes with disinfectants, the efficiency for chlorhexidine was 100%, 97.20% for quaternary ammonium, 87.40% for chlorine and 84.40% for iodine. 75% of the isolates were weak or non-biofilm producers. For the consolidated biofilm, found that iodine decreased biofilm formation in 13 isolates and quaternary ammonia in 11 isolates. The reduction of the biofilm formation was observed for iodine and quaternary ammonium in consolidated biofilm formation in 33% and 28% of the isolates, respectively. The results of this study highlight the importance of establishing measures to prevent and control the disease.

  20. Mesure directe de la distribution de température dans un cristal laser par thermographie infrarouge

    Science.gov (United States)

    Forget, S.; Chénais, S.; Druon, F.; Balembois, F.; Georges, P.

    2004-11-01

    La montée en puissance des lasers solides est fondamentalement limitée par des problèmes thermiques, qui découlent de la transformation d'une partie de l'énergie de pompe en chaleur. Nous présentons ici une méthode simple pour mesurer directement la température absolue à la surface d'un cristal, lorsqu'il est pompé longitudinalement par diode laser. La technique se base sur une caméra infrarouge sensible dans la bande 8-12 μm, et permet de cartographier de façon absolue la température avec une excellente résolution spatiale (de l'ordre de quelques dizaines de μm). Une étude systématique de l'influence du contact thermique sur la distribution de température est présentée, ainsi que la mesure des coefficients de transfert H pour quatre types de contacts thermiques largement utilisés.

  1. Mesure de la fraction d'evenements a quatre quarks dans les desintegrations multihadroniques du boson Z au LEP

    Science.gov (United States)

    Lefebvre, Eric

    Cette thèse propose de tester la Chromodynamique Quantique (QCD) en effectuant une mesure précise d'une des trois constantes fondamentales du groupe de symétrie SU(3) utilisé pour décrire la physique des interactions fortes. Cette constante fondamentale, appelée TF, est reliée à certains états finaux spécifiques des désintégrations du Z0. Ces états apparaissent sous forme de perturbations du deuxième ordre en as et sont illustrés par des diagrammes de Feynman. À cet ordre, la chromodynamique prévoit deux types de diagrammes de Feynman distincts; le premier contient, un quark, un antiquark et deux gluons, et le second, deux quarks et deux antiquarks. La constante TF est directement proportionnelle à la fraction d'événements à deux quarks et deux antiquarks qui est l'objet de notre mesure. Notre mesure est fondée sur l'étude des événements à quatre partons dans l'état final. Ces quatre partons, en s'hadronisant, produisent quatre jets de particules qui peuvent être détectés expérimentalement et identifiés à l'aide d'algorithmes de reconstruction des jets. Des observables angulaires nous permettent de faire une discrimination parmi les états finaux de la désintégration du Z0, et ainsi déterminer la valeur de la fraction d'événements à deux quarks et deux antiquarks fq. Cette fraction peut s'exprimer par le rapport de la fraction observée expérimentalement fexq sur la fraction théorique fthq , R4q=fex qfthq. Afin d'améliorer la mesure de cette fraction et de diminuer le bruit causé par une contamination des événements d'ordres supérieurs, nous avons développe une méthode d'extrapolation. Cette méthode s'appuie sur la caractérisation de l'espace de phase des événements, exprimée par les paramètres yij. Les mesures de R4q que nous obtenons sont: R4q=2,27+0,29 -0,56 à l'aide d'une méthode conventionnelle avec la condition de sélection y34 > 0,020 > y45, et R4q=1,22+0,56 -0,71 à l'aide de notre méthode d

  2. Production of N-13 labeled compounds with high specific activity

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Kazutoshi; Sasaki, Motoji; Yoshida, Yuichiro; Haradahira, Terushi; Inoue, Osamu [National Inst. of Radiological Sciences, Chiba (Japan)

    1997-03-01

    Nitrogen-13 was produced by irradiating ultra pure water saturated with a pure gas (N2, O2, He, H2) with 18 MeV protons. Ion species generated by irradiation were analyzed with radio ion chromatography systems. An automated equipment was developed to synthesize anhydrous (13N)NH3 as a synthetic precursor and (13N)p-nitrophenyl carbamate ((13N)NPC) as a model compound, using the (13N)NH3. The radiochemical yield and specific activity of (13N)NPC was high enough to carry out the receptor study with PET. (author)

  3. The Japanese Amateur Textual Production Scene: Activities and Participation

    Directory of Open Access Journals (Sweden)

    Alvaro David Hernández Hernández

    2016-12-01

    Full Text Available Animation, manga (Japanese comic books, and video games are some of the most popular media in Japan. The huge community of fans and amateur creators that concentrate twice a year at the massive event called Comic Market is one expression of this popularity. In this paper I focus on the Japanese culture of amateur manga, anime or other derivative texts, and present analysis of the way in which members relate to media texts and other members, in order to reveal two different orientations towards action within this culture: one that centers on individual activities, and the other on collective participation. To do this, I focus first on the Japanese amateur culture that is often called dōjin culture to find two basic perspectives. One regards this culture as forming communities or based on social interaction, and the other denies commonality in the relationships between members and stresses individual drive. Then, I focus on a similar distinction that shapes the main discourses concerning Japanese subculture and otaku, both categories within which dōjin culture can be categorized. Here I pay particular attention to two different orientations towards the value of media texts, which provide a reference for understanding the aforementioned opposition between commonality and individuality. In my conclusions, I suggest that this amateur culture can be regarded as an institution of textual appropriation, shaped by two orientations: activities and participation. 

  4. Antioxidant activity and phenolic content of agricultural by-products from wine production

    OpenAIRE

    Cataneo, Ciriele Boeira; Universidade Federal de Santa Catarina; Caliari, Vinícius; Epagri; Gonzaga, Luciano Valdemiro; Universidade Federal de Santa Catarina; Kuskoski, Eugênia Marta; Universidade Federal de Santa Catarina; Fett, Roseane; Universidade Federal de Santa Catarina

    2008-01-01

    The present work aimed to investigate the antioxidant properties of byproducts derived from wine production. The varieties of PINOT GRIS and COUDERC 13 grapes, collected in Videira-SC, were analyzed as natural sources of polyphenols and other prophylactic agents (antioxidants) for application in food and phytochemical industries. The biomass used for extracts was ground and dried in different temperatures (45oC, 60oC e 80oC), using acetone 80% as solvent. The phenolic compounds were quantitat...

  5. Plan now to make your retirement active, productive.

    Science.gov (United States)

    Schlepp, S

    1989-12-01

    In his book Planning to the Years Ahead, Lester I. Tenney, PhD, professor emeritus at Arizona State University, Tempe, links Abraham Maslow's hierarchy of needs to retirement planning. According to Maslow, economic and security needs can be achieved through a family environment (eg, food clothing, shelter), and social acceptance, self-worth, and self-satisfaction can be achieved from social interaction, work, or leisure activities. After the basic needs of food, clothing, and shelter have been achieved, people are able to move to the next level of achieving safety and security. The level of dependency that people have on satisfying these needs through work will determine how well they are at adapting to retirement. The more people depend on work alone, the harder will be the adjustment; people who are less dependent on work will find retirement easier to accept.

  6. Activation of frontal neocortical areas by vocal production in marmosets

    Directory of Open Access Journals (Sweden)

    Cristiano S Simões

    2010-09-01

    Full Text Available Primates often rely on vocal communication to mediate social interactions. Although much is known about the acoustic structure of primate vocalizations and the social context in which they are usually uttered, our knowledge about the neocortical control of audio-vocal interactions in primates is still incipient, being mostly derived from lesion studies in squirrel monkeys and macaques. To map the neocortical areas related to vocal control in a New World primate species, the common marmoset, we employed a method previously used with success in other vertebrate species: Analysis of the expression of the immediate-early gene Egr-1 in freely behaving animals. The neocortical distribution of Egr-1 immunoreactive cells in three marmosets that were exposed to the playback of conspecific vocalizations and vocalized spontaneously (H/V group was compared to data from three other marmosets that also heard the playback but did not vocalize (H/n group. The anterior cingulate cortex, the dorsomedial prefrontal cortex and the ventrolateral prefrontal cortex presented a higher number of Egr-1 immunoreactive cells in the H/V group than in H/n animals. Our results provide direct evidence that the ventrolateral prefrontal cortex, the region that comprises Broca's area in humans and has been associated with auditory processing of species-specific vocalizations and orofacial control in macaques, is engaged during vocal output in marmosets. Altogether, our results support the notion that the network of neocortical areas related to vocal communication in marmosets is quite similar to that of Old world primates. The vocal production role played by these areas and their importance for the evolution of speech in primates are discussed.

  7. A novel AMPK activator hernandezine inhibits LPS-induced TNFα production.

    Science.gov (United States)

    Li, Ping; Li, Xiaofang; Wu, Yonghong; Li, Manxiang; Wang, Xiaochuang

    2017-09-15

    Here, we found that hernandezine, a novel AMPK activator, inhibited LPS-induced TNFα expression/production in human macrophage cells (THP-1 and U937 lines). Activation of AMPK is required for hernandezine-induced anti-LPS response. AMPKα shRNA or dominant negative mutation (T172A) blocked hernandezine-induced AMPK activation, which almost completely reversed anti-LPS activity by hernandezine. Exogenous expression of the constitutively activate AMPKα (T172D, caAMPKα) also suppressed TNFα production by LPS. Remarkably, hernandezine was unable to further inhibit LPS-mediated TNFα production in caAMPKα-expressing cells. Hernandezine inhibited LPS-induced reactive oxygen species (ROS) production and nuclear factor kappa B (NFκB) activation. Treatment of hernandezine in ex-vivo cultured primary human peripheral blood mononuclear cells (PBMCs) also largely attenuated LPS-induced TNFα production. Together, we conclude that AMPK activation by hernandezine inhibits LPS-induced TNFα production in macrophages/monocytes.

  8. Active Pesticide Production Points, Region 9, 2013, US EPA Region 9

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data layer represents Active Pesticide Producing Establishments in USEPA Region 9 (AZ, CA, HI and NV) that reported production for the year 2013. Pesticide...

  9. Pesticide Active Ingredient Production Industry: National Emission Standards for Hazardous Air Pollutants (NESHAP)

    Science.gov (United States)

    This action promulgates national emission standards for hazardous air pollutants (NESHAP) for the pesticide active ingredient (PAI) production source category under section 112 of the Clean Air Act as amended (CAA or Act).

  10. Methodical Approach to Diagnostics of Efficiency of Production Economic Activity of an Enterprise

    Directory of Open Access Journals (Sweden)

    Zhukov Andrii V.

    2014-03-01

    Full Text Available The article offers developments of a methodical approach to diagnostics of efficiency of production economic activity of an enterprise, which, unlike the existing ones, is realised through the following stages: analysis of the enterprise external environment; analysis of the enterprise internal environment; identification of components of efficiency of production economic activity for carrying out complex diagnostics by the following directions: efficiency of subsystems of the enterprise production economic activity, efficiency of use of separate types of resources and socio-economic efficiency; scorecard formation; study of tendencies of change of indicators; identification of cause-effect dependencies between the main components of efficiency for diagnosing reasons of its level; diagnosing deviations of indicator values from their optimal values; development of a managerial decision on preserving and increasing efficiency of production economic activity of the enterprise.

  11. Measurement and analysis of radioactive substances; Mesure et analyse de substances radioactives

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    Here are gathered the abstracts presented to the 3. summer university of the year 2001 whose main themes were the destructive (5 conferences) and nondestructive (8 conferences) analyses applied to nuclear industry. The points of view of different organisms (as DSIN: Directorate for the Safety of Nuclear Installations, IPSN: Institute of Nuclear Protection and Safety, OPRI: Office of Protection against Ionizing Radiations, TUI: Institute for Transuranium Elements, COGEMA, EDF: Electric Utilities, ANDRA: French National Agency for Radioactive Waste Management, CRLC Val d'Aurelle, France) concerning the needs involved in nuclear facilities control, the methods of radionuclide speciation in use internationally, the measurements and analyses of radioactive substances are given too as well as some general concepts concerning 1)the laser-matter interaction 2)the ions production 3)the quality applied to the measurements and analyses 4)the standard in activity metrology. (O.M.)

  12. Production of high specific activity 123I for protein iodination for medical use

    International Nuclear Information System (INIS)

    Legoux, Y.; Cieur, M.; Crouzel, C.; Syrota, A.

    1985-01-01

    Iodine-123 is produced via xenon-133 by irradiation of a sodium iodide target with 108 MeV deuterons from the synchrocyclotron of IPN. The on-line production method is described. The specific activity of the iodine is determined by neutron activation analysis and by a radioimmunological method. The conditions labelling different proteins (insulin, angiotensin) are given and also the purification method to obtain a product ready for injection to patients. (author)

  13. [Features of memory and intellectual activity among the elderly with different reading productivity].

    Science.gov (United States)

    Yemelianova, T V; Sokolova, L V; Dzhos, Yu S

    The aim of this work was the study of indicators of memory and intellectual activity among the elderly with different reading productivity. The results of the study showed that the elderly were distinguished by a greater number of errors when performing tasks on oral-aural, visual memory and visual-spatial activities. The mistakes made by subjects with low reading productivity may indicate dysfunction of tone and wakefulness, of receiving, processing and storing information, as well as weakening of hemispheric interaction.

  14. Activity Analysis: Bridging the Gap between Production Economics Theory and Practical Farm Management Procedures

    OpenAIRE

    Longworth, John W.; Menz, Kenneth M.

    1980-01-01

    This paper is addressed to the traditional problem of demonstrating the relevance of production theory to management-oriented people. Activity analysis, it is argued, is the most appropriate pedagogic framework within which to commence either a production economics or a farm management course. Production economics theory has not been widely accepted as a useful method for the analysis of practical management problems. The theory has been traditionally presented in terms of continuous function...

  15. Tumor necrosis factor induces the production of urokinase-type plasminogen activator by human endothelial cells

    NARCIS (Netherlands)

    Hinsbergh, V.W.M. van; Berg, E.A. van den; Fiers, W.; Dooijewaard, G.

    1990-01-01

    Endothelial cells play an important role in the regulation of fibrinolysis by the production of several key regulatory proteins. The cytokines tumor necrosis factor (TNF), lymphotoxin, and interleukin-1 (IL-1), but not interleukin-6, increase the production of plasminogen activator inhibitor-1

  16. The Chemistry of Self-Heating Food Products: An Activity for Classroom Engagement

    Science.gov (United States)

    Oliver-Hoyo, Maria T.; Pinto, Gabriel; Llorens-Molina, Juan Antonio

    2009-01-01

    Two commercial self-heating food products have been used to apply chemical concepts such as stoichiometry, enthalpies of reactions and solutions, and heat transfer in a classroom activity. These products are the self-heating beverages sold in Europe and the Meals, Ready to Eat or MREs used primarily by the military in the United States. The main…

  17. 78 FR 28577 - Notification of Proposed Production Activity, LLFlex, LLC, Subzone 29J (Foil Backed Paperboard...

    Science.gov (United States)

    2013-05-15

    ... Foreign-Trade Zones Board Notification of Proposed Production Activity, LLFlex, LLC, Subzone 29J (Foil...) was received on May 6, 2013. The subzone currently has authority to produce aluminum foil liner stock. The current request would add foil backed paperboard to the list of approved finished products...

  18. 78 FR 55057 - Subzone 29J, Authorization of Production Activity, LLFlex, LLC; (Foil Backed Paperboard...

    Science.gov (United States)

    2013-09-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Subzone 29J, Authorization of Production Activity, LLFlex, LLC; (Foil Backed Paperboard), Louisville, Kentucky On May 6, 2013, LLFlex, LLC submitted a notification of proposed production...

  19. Calculation of radiation production of high specific activity isotopes 192Ir and 60Co

    International Nuclear Information System (INIS)

    Zhou Quan; Zhong Wenfa; Xu Xiaolin

    1997-01-01

    The high specific activity isotopes: 192 Ir and 60 Co in the high neutron flux reactor are calculated with the method of reactor physics. The results of calculation are analyzed in two aspects: the production of isotopes and the influence to parameters of the reactor, and hence a better case is proposed as a reference to the production

  20. A hands-on activity for teaching product-process matrix: roadmap and application

    Directory of Open Access Journals (Sweden)

    Luciano Costa Santos

    2014-08-01

    Full Text Available The product-process matrix is a well-known framework proposed by Hayes and Wheelwright (1979 that is commonly used to identify processes types and to analyze the alignment of these processes with the products of a company. For didactic purposes, the matrix helps undergraduates beginners from Production Engineering to understand the logic of production systems, providing knowledge that will be essential for various course subjects. Considering the high level of abstraction of the concepts underlying the product-process matrix, this paper presents a way to facilitate the learning of them through the application of a hands-on activity which relies on the active learning philosophy. The proposed dynamic uses colored plastic sheets and PVC pipes as main materials, differing from the original proposal of Penlesky and Treleven (2005 . In addition to presenting an extremely simple exercise, which encourages its application in the classroom, another contribution of this paper is to define a complete roadmap for conducting the activity. This roadmap describes the assembly of fictitious products in customization and standardization scenarios for the comparison of two processes types of product-process matrix, job shop and assembly line. The activity revealed very successful after its application to two groups of Production Engineering undergraduates, confirmed with positive feedback from the students surveyed.

  1. The influence of business strategy on new product activity: the role of market orientation

    NARCIS (Netherlands)

    Frambach, R.T.; Prabhu, Jaideep; Verhallen, T.M.M.

    2003-01-01

    In this paper, we propose that business strategy influences new product activity both directly and indirectly via its influence on market orientation. Accordingly, we develop a framework linking firms' relative emphasis on cost leadership, product differentiation and focus strategies to firms'

  2. Production of activated carbon from peanut hill using phosphoric acid and microwave activation

    Directory of Open Access Journals (Sweden)

    Weerawat Clowutimon

    2015-06-01

    Full Text Available The optimum conditions for preparing activated carbon from peanut hulls by phosphoric acid and microwave activation were studied. Factors investigated in this study were temperature of carbonization at 300, 350, 400 and 450๐ C, and time of carbonization at 30, 60 and 90 minutes. The optimum yield was observed that carbonization temperature of 400๐ C and time at 60 minutes, respectively. The yield of charcoal was 39% and the f ix carbon was 69%. Then the charcoal was activated by phosphoric acid and microwave irradiation, respectively. The effect of the weight per volume ratios of charcoal to activating acid (1:1, 1:2 and 2:1(W/V, microwave power at (activated 300, 500 and 700 watts, and activated time (30, 60 and 90 seconds were studied. The results showed that the optimum conditions for activating peanut charcoal were 1:2 (W/V charcoal per activating acid, microwave power 700 watts for 90 seconds. The results yielding maximum surface area by BET method was 303.1 m2 /g and pore volume was 0.140 cm3 /g. An efficiency of maximum iodine adsorption was 418 mg iodine/g activated carbon. Comparing the adsorption efficiency of non- irradiated and irradiated activated carbon, the efficiency of irradiated activated carbon improved up to 31%, due to its larger surface area and pore volume.

  3. Effects of Lipotropic Products on Productive Performance, Liver Lipid and Enzymes Activity in Broiler Chickens

    Directory of Open Access Journals (Sweden)

    Khosravinia H

    2015-12-01

    Full Text Available In a 42-d experiment, 576 one-day-old Vencobb 308 broiler chicks were used to investigate the effects of lecithin extract (0.5 g/kg, choline chloride 60% (1 g/kg and Bio choline (1 g/kg in diets of moderate and high energy in a 4 × 2 factorial arrangement on performance and certain physiological traits in broiler chickens. The inclusion of Bio choline and lecithin extract in the diet significantly increased average daily gain and improved feed conversion ratio  in overall (1 to 42 d period (P < 0.05. Performance efficiency index was improved in the birds fed with Bio choline compared to those fed control diet. Broilers fed diets containing Bio choline and lecithin extract had less abdominal fat percentage than those fed choline chloride or control diet. Regardless of dietary energy level, supplementation of diet with Bio choline, choline chloride and lecithin extract significantly decreased liver lipid concentration (P < 0.05. Aspartate aminotransferase activity increased in the serum of broilers fed high energy diets while it was decreased in the birds received diets containing choline chloride. Lipotropic compounds decreased serum aspartate aminotransferase activity in the birds fed on high energy diets. The addition of Bio choline and lecithin extract to diet significantly decreased serum γ–glutamyltransferase activity (P < 0.05. Results of the present study revealed that dietary supplementation of commercial lipotropic compounds could remove potential detrimental effects from high energy diets through reducing liver fat and maintaining liver health.

  4. Inhibitory Activities of Alkyl Syringates and Related Compounds on Aflatoxin Production.

    Science.gov (United States)

    Furukawa, Tomohiro; Iimura, Kurin; Kimura, Taichi; Yamamoto, Toshiyoshi; Sakuda, Shohei

    2016-06-07

    Inhibitors of aflatoxin production of aflatoxigenic fungi are useful for preventing aflatoxin contamination in crops. As methyl syringate weakly inhibits aflatoxin production, aflatoxin production inhibitory activities of additional alkyl syringates with alkyl chains from ethyl to octyl were examined. Inhibitory activity toward aflatoxin production of Aspergillus flavus became stronger as the length of the alkyl chains on the esters became longer. Pentyl, hexyl, heptyl, and octyl syringates showed strong activity at 0.05 mM. Heptyl and octyl parabens, and octyl gallate also inhibited aflatoxin production as strongly as octyl syringate. Alkyl parabens and alkyl gallates inhibit the complex II activity of the mitochondrial respiration chain; thus, whether alkyl syringates inhibit complex II activity was examined. Inhibitory activities of alkyl syringates toward complex II also became stronger as the length of the alkyl chains increased. The complex II inhibitory activity of octyl syringate was comparable to that of octyl paraben and octyl gallate. These results suggest that alkyl syringates, alkyl parabens, and alkyl gallates, including commonly used food additives, are useful for aflatoxin control.

  5. Inhibitory Activities of Alkyl Syringates and Related Compounds on Aflatoxin Production

    Directory of Open Access Journals (Sweden)

    Tomohiro Furukawa

    2016-06-01

    Full Text Available Inhibitors of aflatoxin production of aflatoxigenic fungi are useful for preventing aflatoxin contamination in crops. As methyl syringate weakly inhibits aflatoxin production, aflatoxin production inhibitory activities of additional alkyl syringates with alkyl chains from ethyl to octyl were examined. Inhibitory activity toward aflatoxin production of Aspergillus flavus became stronger as the length of the alkyl chains on the esters became longer. Pentyl, hexyl, heptyl, and octyl syringates showed strong activity at 0.05 mM. Heptyl and octyl parabens, and octyl gallate also inhibited aflatoxin production as strongly as octyl syringate. Alkyl parabens and alkyl gallates inhibit the complex II activity of the mitochondrial respiration chain; thus, whether alkyl syringates inhibit complex II activity was examined. Inhibitory activities of alkyl syringates toward complex II also became stronger as the length of the alkyl chains increased. The complex II inhibitory activity of octyl syringate was comparable to that of octyl paraben and octyl gallate. These results suggest that alkyl syringates, alkyl parabens, and alkyl gallates, including commonly used food additives, are useful for aflatoxin control.

  6. La mesure des performances corporelles extraordinaires dans les métiers du sport, du luxe et de l’art

    Directory of Open Access Journals (Sweden)

    Stéphane Héas

    2009-10-01

    Full Text Available La mesure des performances est aujourd’hui omniprésente dans les sports. Cette quantification corporelle n’étonne plus outre mesure. Elle est devenue sociologique. Les affaires de dopage ne fragilisent pas cette tendance. Les performances sportives de l’élite mondiale sont devenues très éloignées de ce que le commun des mortels peut envisager. Elles sont incroyables et pourtant réelles. Parfois, une fraction de seconde seulement sépare le bonheur de la victoire de la désillusion d’une défaite. En dehors des arènes sportives, d’autres performances sont réalisées. C’est le cas par exemple des équilibristes, des «nez» dans de nombreux secteurs (viniculture, cosmétique, etc., des contorsionnistes, des imitateurs, etc. A travers 21 entretiens, nous esquissons l’étendue des performances réalisées, donc leurs mesures multiples. Comment ces performances, le plus souvent chiffrées (en nombre de fragrances testées par jour, en minutes d’équilibre maintenu sur un rouleau, etc., sont-elles vécues? Les exercices et les excès corporels sont devenus leur quotidien, la mesure, leur étalon… qu’ils tentent de maintenir ou de varier avec l’âge, à mesure que leurs capacités déclinent.

  7. Processes for the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity

    DEFF Research Database (Denmark)

    2016-01-01

    The present invention generally relates to the field of biotechnology as it applies to the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity. More particularly, the present invention pertains to polypeptides having tyrosine ammonia lyase activity and high...... substrate specificity towards tyrosine, which makes them particularly suitable in the production of p-coumaric acid and other hydroxycinnamic acids. The present invention thus provides processes for the production of p-coumaric acid and other hydroxycinnamic acids employing these polypeptides as well...

  8. Briquetting and carbonization of biomass products for the sustainable productions of activated carbons

    Science.gov (United States)

    Khorasgani, Nasrin B.; Karimibavani, Bahareh; Alamir, Mohammed; Alzahrani, Naif; McClain, Amy P.; Asmatulu, Ramazan

    2017-04-01

    One of the most environmental concerns is the climate change because of the greenhouse gasses, such as CO2, N2O, CH4, and fluorinated gases. The big majority of CO2 is coming from burning of fossil fuels to generate steam, heat and power. In order to address some of the major environmental concerns of fossil fuels, a number of different alternatives for renewable energy sources have been considered, including sunlight, wind, rain, tides and geothermal heat and biomass. In the present study, two different biomass products (three leaves and grasses) were collected from the local sources, cleaned, chopped, and mixed with corn starch as a binder prior to the briquetting process at different external loads in a metallic mold. A number of tests, including drop, ignition and mechanical compression were conducted on the prepared briquettes before and after stabilizations and carbonization processes at different conditions. The test results indicated that briquetting pressure and carbonizations are the primary factors to produce stable and durable briquettes for various industrial applications. Undergraduate students have been involved in every step of the project and observed all the details of the process during the laboratory studies, as well as data collection, analysis and presentation. This study will be useful for the future trainings of the undergraduate engineering students on the renewable energy and related technologies.

  9. Report made on behalf of the inquiry commission for the enforcement of the measures preconized for the safety of the maritime transport of hazardous or polluting products and for the evaluation of their efficiency; Rapport fait au nom de la commission d'enquete sur l'application des mesures preconisees en matiere de securite du transport maritime des produits dangereux ou polluants et l'evaluation de leur efficacite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    On February 5, 2003, three years after the creation of an inquiry commission about the Erika tanker-ship wreck, the principle of a new inquiry commission about the safety of maritime transports was decided by the French house of commons. Its mission is: to evaluate the efficiency of the existing measures of prevention of marine pollution by hydrocarbons, to examine if the preconized safety measures for the transport of dangerous or polluting products are effectively enforced, and to evaluate the status of the transposition of the European directives relative to the control of hazardous ships. This document is the first tome of the report made on behalf of this inquiry commission. It comprises four parts dealing with: 1 - the Prestige tanker-ship wreck and the pollution of Spanish and French coasts: similarities with the Erika wreck but differences in the conditions of crisis management, diverging accident analyses, problems encountered in Spain, a significantly improved management of the crisis by the French administration, the public opinion and the local economy, the global increase of maritime transport and the reduction of accidents frequency; 2 - the real improvements after the Erika wreck: the significant advances but their partial implementation, the acceleration of actions following the Prestige wreck; 3 - the expected and realistic perspectives: the sustain of the political will at the national scale, the concretizing of the European decisions and the follow up of the retained trends, the need for more outstanding evolutions at the international scale; 4 - the international liability and compensation regime: its limitation to the hydrocarbons pollution, the lack of victims indemnification in the case of chemical pollution, the need for an increase of the liability of all actors of the maritime transport and the improvement of the compensation system, a community compensation fund to compensate the inefficiencies of the international compensation mechanisms

  10. Production of Low Calorie Bakery Product with Pleasant Flavour, Antioxidant and Antimicrobial Activities

    Directory of Open Access Journals (Sweden)

    Hussein Ahmed M.S.

    2014-12-01

    Full Text Available Aromatic plants are considered sources of antioxidants, antimicrobial and favouring agents. Four aromatic plants (Thymus vulgaris L., Foeniculum vulgare, Pimpinella anisum L. and Trigonellafoenum-graecum L. were analysed in the study. Yoghurt was used to produce a low calorie pie. Chemical and rheological parameters, baking performance, staling rate and sensory properties of the pie were investigated. Volatile aroma compounds were anal-ysed with GC and GC/ MS, and antioxidant activity was evaluated by DPPH and β-carotene assays. The incorporation of yoghurt and some aromatic plants in the pie improved protein, fat, fibre, ash, and minerals contents and allowed achieving about 19% reduction in calories. Sensory evaluation of pie containing the mixture of aromatic plants showed its superior sensory quality. In addition, it could be concluded that aromatic plants were able to inhibit the growth of yeast, mould and bacteria and to prolong the storage periods of pie compared with the control.

  11. 78 FR 13857 - Foreign-Trade Zone 93-Raleigh-Durham, NC; Authorization of Production Activity; Revlon Consumer...

    Science.gov (United States)

    2013-03-01

    ...; Revlon Consumer Products Corporation (Hair Coloring Products); Oxford, NC On October 10, 2012, Revlon... activity to the Foreign-Trade Zones (FTZ) Board on behalf of Revlon Consumer Products Corporation, within...

  12. Effects of cysteine on growth, protease production, and catalase activity of Pseudomonas fluorescens.

    OpenAIRE

    Himelbloom, B H; Hassan, H M

    1986-01-01

    Cysteine inhibits growth of and protease production by Pseudomonas fluorescens NC3. Catalase activity in P. fluorescens NC3 was increased by cysteine. The addition of exogenous hydrogen peroxide did not increase catalase activity, thus suggesting a role for the endogenous generation of hydrogen peroxide via the autoxidation of cysteine.

  13. Radiometric measurement of lead-201 and thallium-201 activity in industrial production of thallium chlorides

    International Nuclear Information System (INIS)

    Skokov, V.S.; Azbel', G.A.

    1989-01-01

    The spectrometric methods and equipment for 201 Pb and 201 Tl activity control in the prepared thallium chloride in industrial production are described. Estimation of thallium-201 activity is carried out in accord with the square of summary photopeak caused by γ-quanta at 167 keV energy. Attenuation is paid to spectrometer calibration. 5 refs.; 2 figs.; 2 tabs

  14. Compatibility of accounting information systems (AISs with activities in production cycle

    Directory of Open Access Journals (Sweden)

    Farnaz Vali Moghaddam Zanjani

    2013-01-01

    Full Text Available The intricacies of economic activities and growing increase in competition have made commercial units with the duty of production and financial data processing, orienting themselves with production cycle. This is considered as the heart of organization such that they could be more effective in decision-making. The method adopted in this research is descriptive – survey and it attempts to attain the objectives the researchers based on four independent variables including Production design, Programming, production operations and cost accounting. To test the hypotheses, the study adopts one sample T test method and to investigate uniformity of effects of each variable, Kruscal-Wallis test is employed. The results obtained from the tests indicate that AISs are not compatible with production cycle, where, in turn, has led to rejection of modern costing systems such as activity based costing (ABC.

  15. Advance Planning, Programming and Production Control as key Activities Now the Environmental Education

    Directory of Open Access Journals (Sweden)

    Geraldo Cardoso de Oliveira Neto

    2015-06-01

    Full Text Available This work addresses the evolution of Planning, Programming and Control of Production (PPCP as essential activities of the company towards the insertion of environmental education. The approach is based on an exploratory research and a critical bibliographic revision. Two main objectives were established: i a new way of production organization, by considering cleaner production from company utilities to production capacity, technology and outsourcing and ii infrastructure changes related to market attendance and environmental education dissemination. Needs that arise can be grouped as follows: utilities adequacy, cleaner technologies and ecochains implementation; instruction and dissemination of environmental education; and necessity of the adoption of new paradigms.

  16. Mesure de vitesse acoustique dans un écoulement de conduite turbulent par LDV et TR-PIV

    OpenAIRE

    Léon , Olivier; Piot , Estelle; Sebbane , Delphine; Simon , Frank

    2016-01-01

    International audience; Ces travaux visent à montrer la faisabilité de la mesure de composantes de vitesse acoustique, i.e. amplitude et phase, dans un écoulement de conduite pleinement turbulent par TR-PIV et LDV, pour des conditions d’essais présentant des amplitudes sonores d’au moins 130dB, des nombres de Mach de l’ordre de 0.1 et des taux de turbulence supérieurs à 5%. L’objectif à long terme est de mettre en oeuvre la technique TR-PIV dans des conditions d’essais rencontrées dans l’étud...

  17. Chemical Characterization, Antioxidant and Enzymatic Activity of Brines from Scandinavian Marinated Herring Products

    DEFF Research Database (Denmark)

    Gringer, Nina; Osman, Ali; Nielsen, Henrik Hauch

    2014-01-01

    Brines generated during the last marination step in the production of marinated herring (Clupea harengus) were chemically characterized and analyzed for antioxidant and enzyme activities. The end-products were vinegar cured, spice cured and traditional barrel-salted herring with either salt...... or spices. The chemical characterization encompassed pH, dry matter, ash, salt, fatty acids, protein, polypeptide pattern, iron and nitrogen. The antioxidant activity was tested with three assays measuring: iron chelation, reducing power and radical scavenging activity. The enzymatic activity for peroxidase...... and protease were also tested. Results revealed that the brine can contain up to 56.7 mg protein/ mL, up to 20.1 mg fatty acid/mL, good antioxidant activity, high amounts of the antioxidative amino acids lysine, alanine, and glycine, and high enzymatic activity. The potential of using the protein-rich fraction...

  18. Antifeedant activity of xanthohumol and supercritical carbon dioxide extract of spent hops against stored product pests.

    Science.gov (United States)

    Jackowski, J; Hurej, M; Rój, E; Popłoński, J; Kośny, L; Huszcza, E

    2015-08-01

    Xanthohumol, a prenylated flavonoid from hops, and a supercritical carbon dioxide extract of spent hops were studied for their antifeedant activity against stored product insect pests: Sitophilus granarius L., Tribolium confusum Duv. and Trogoderma granarium Everts. Xanthohumol exhibited medium deterrent activity against the adults of S. granarius L. and larvae of T. confusum Duv. The spent hops extract was more active than xanthohumol towards the adults of T. confusum Duv. The potential application of the crude spent hops extract as a feeding deterrent against the stored product pests is proposed.

  19. Production of activated carbons from waste tyres for low temperature NOx control

    OpenAIRE

    Al-Rahbi, AS; Williams, PT

    2016-01-01

    Waste tyres were pyrolysed in a bench scale reactor and the product chars were chemically activated with alkali chemical agents, KOH, K2CO3, NaOH and Na2CO3 to produce waste tyre derived activated carbons. The activated carbon products were then examined in terms of their ability to adsorb NOx (NO) at low temperature (25°C) from a simulated industrial process flue gas. This study investigates the influence of surface area and porosity of the carbons produced with the different alkali chemical...

  20. Investigating the Structure-Activity Relationship of the Insecticidal Natural Product Rocaglamide.

    Science.gov (United States)

    Hall, Roger G; Bruce, Ian; Cooke, Nigel G; Diorazio, Louis J; Cederbaum, Fredrik; Dobler, Markus R; Irving, Ed

    2017-12-01

    The natural product Rocaglamide (1), isolated from the tree Aglaia elliptifolia, is a compelling but also challenging lead structure for crop protection. In laboratory assays, the natural product shows highly interesting insecticidal activity against chewing pests and beetles, but also phytotoxicity on some crop plants. Multi-step syntheses with control of stereochemistry were required to probe the structure-activity relationship (SAR), and seek simplified analogues. After a significant research effort, just two areas of the molecule were identified which allow modification whilst maintaining activity, as will be highlighted in this paper.

  1. Participation of Urban Women in Agricultural Production Activities in the Sokoto Metropolis, Nigeria

    Directory of Open Access Journals (Sweden)

    Barau, A. A.

    2017-10-01

    Full Text Available This study examines the participation of urban women in agricultural production activities in the Sokoto metropolis, Nigeria. Both primary data and secondary information were used in the study. The primary data were obtained using a structured questionnaire, administered to 72 respondents selected using the snowball sampling technique. Descriptive and inferential statistics were used to analyze the primary data generated. These include frequency and percentage, and Pearson product moment correlation, respectively. The results show that most of the urban women (38.9 % were in the active age range and had a family size of 1-5 persons (73.6 %. The majority attained tertiary education (62.5 % and have relatively low income (61.1 %, with monthly earnings of 5,000-99,000 Naira. The majority of the women were involved in agricultural production activities all year round (52.8 % with the highest participation seen in poultry farming (43.1 %. Although most of the women were motivated to participate for several reasons, it was mostly for the increased income (33.3 %. It was also found that the major constraint faced was inadequate capital (43.1 %. Age, marital status, educational attainment, household size and farm size were negatively and not significantly (p<5 % related to the participation of urban women in agricultural production activities. Monthly income was however, positively related to the urban women’s participation in agricultural production activities and was also significant (p<5 %. In general, urban women participate in agricultural production activities on a small scale all year round. Proper orientation and awareness programs, provision of credit and women-targeted agricultural programs would go a long way to improving the participation of urban women in agricultural production activities.

  2. Influence of activated carbon amended ASBR on anaerobic fermentative hydrogen production

    DEFF Research Database (Denmark)

    Xie, Li; Wang, Lei; Zhou, Qi

    2013-01-01

    The effect of activated carbon amended ASBR on fermentative bio-hydgrogen production from glucose was evaluated at hydraulic retention time (HRTs) ranging from 48 h to 12 h with initial pH of 6.0 at the system temperature of 60°C. Experimental results showed that the performance of activated carbon...... amended anazrobic seguencs batch reactor (ASBRs) was more stable than that of ASBRs without activated carbon addition regarding on hydrogen production and pH. Higher hydrogen yield(HY) and hydrogen producing rate(HPR) were observed in the activated carbon amended ASBRs, with 65%, 63%, 54%, 56% enhancement......%~66% and 30%~34% of total soluble metabolic products(SMP), respectively, indicating that the dominant H2 producers in the mixed culture belonged to acidogenic bacteria that underwent butyrate-type fermentation. In addition, higher concentration of volatile fatty acid (VFA) generation was observed...

  3. Listening to Puns Elicits the Co-Activation of Alternative Homophone Meanings during Language Production.

    Directory of Open Access Journals (Sweden)

    Sebastian Benjamin Rose

    Full Text Available Recent evidence suggests that lexical-semantic activation spread during language production can be dynamically shaped by contextual factors. In this study we investigated whether semantic processing modes can also affect lexical-semantic activation during word production. Specifically, we tested whether the processing of linguistic ambiguities, presented in the form of puns, has an influence on the co-activation of unrelated meanings of homophones in a subsequent language production task. In a picture-word interference paradigm with word distractors that were semantically related or unrelated to the non-depicted meanings of homophones we found facilitation induced by related words only when participants listened to puns before object naming, but not when they heard jokes with unambiguous linguistic stimuli. This finding suggests that a semantic processing mode of ambiguity perception can induce the co-activation of alternative homophone meanings during speech planning.

  4. Waste production and regional growth of marine activities an econometric model.

    Science.gov (United States)

    Bramati, Maria Caterina

    2016-11-15

    Coastal regions are characterized by intense human activity and climatic pressures, often intensified by competing interests in the use of marine waters. To assess the effect of public spending on the regional economy, an econometric model is here proposed. Not only are the regional investment and the climatic risks included in the model, but also variables related to the anthropogenic pressure, such as population, economic activities and waste production. Feedback effects of economic and demographic expansion on the pollution of coastal areas are also considered. It is found that dangerous waste increases with growing shipping and transportation activities and with growing population density in non-touristic coastal areas. On the other hand, the amount of non-dangerous wastes increases with marine mining, defense and offshore energy production activities. However, lower waste production occurs in areas where aquaculture and touristic industry are more exploited, and accompanied by increasing regional investment in waste disposal. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Statistics of Infima and Stopping Times of Entropy Production and Applications to Active Molecular Processes

    Science.gov (United States)

    Neri, Izaak; Roldán, Édgar; Jülicher, Frank

    2017-01-01

    We study the statistics of infima, stopping times, and passage probabilities of entropy production in nonequilibrium steady states, and we show that they are universal. We consider two examples of stopping times: first-passage times of entropy production and waiting times of stochastic processes, which are the times when a system reaches a given state for the first time. Our main results are as follows: (i) The distribution of the global infimum of entropy production is exponential with mean equal to minus Boltzmann's constant; (ii) we find exact expressions for the passage probabilities of entropy production; (iii) we derive a fluctuation theorem for stopping-time distributions of entropy production. These results have interesting implications for stochastic processes that can be discussed in simple colloidal systems and in active molecular processes. In particular, we show that the timing and statistics of discrete chemical transitions of molecular processes, such as the steps of molecular motors, are governed by the statistics of entropy production. We also show that the extreme-value statistics of active molecular processes are governed by entropy production; for example, we derive a relation between the maximal excursion of a molecular motor against the direction of an external force and the infimum of the corresponding entropy-production fluctuations. Using this relation, we make predictions for the distribution of the maximum backtrack depth of RNA polymerases, which follow from our universal results for entropy-production infima.

  6. Statistics of Infima and Stopping Times of Entropy Production and Applications to Active Molecular Processes

    Directory of Open Access Journals (Sweden)

    Izaak Neri

    2017-02-01

    Full Text Available We study the statistics of infima, stopping times, and passage probabilities of entropy production in nonequilibrium steady states, and we show that they are universal. We consider two examples of stopping times: first-passage times of entropy production and waiting times of stochastic processes, which are the times when a system reaches a given state for the first time. Our main results are as follows: (i The distribution of the global infimum of entropy production is exponential with mean equal to minus Boltzmann’s constant; (ii we find exact expressions for the passage probabilities of entropy production; (iii we derive a fluctuation theorem for stopping-time distributions of entropy production. These results have interesting implications for stochastic processes that can be discussed in simple colloidal systems and in active molecular processes. In particular, we show that the timing and statistics of discrete chemical transitions of molecular processes, such as the steps of molecular motors, are governed by the statistics of entropy production. We also show that the extreme-value statistics of active molecular processes are governed by entropy production; for example, we derive a relation between the maximal excursion of a molecular motor against the direction of an external force and the infimum of the corresponding entropy-production fluctuations. Using this relation, we make predictions for the distribution of the maximum backtrack depth of RNA polymerases, which follow from our universal results for entropy-production infima.

  7. Safety aspects of activation products in a compact Tokamak Fusion Power Plant

    International Nuclear Information System (INIS)

    Willenberg, H.J.; Bickford, W.E.

    1978-10-01

    Neutron activation of materials in a compact tokamak fusion reactor has been investigated. Results of activation product inventory, dose rate, and decay heat calculations in the blanket and injectors are presented for a reactor design with stainless steel structures. Routine transport of activated materials into the plasma and vacuum systems is discussed. Accidental release of radioactive materials as a result of liquid lithium spills is also considered

  8. Development of highly microporous activated carbon from the alcoholic beverage industry organic by-products

    International Nuclear Information System (INIS)

    Nieto-Delgado, C.; Terrones, M.; Rangel-Mendez, J.R.

    2011-01-01

    This work has the aim to employ the agave bagasse, a waste from Tequila and Mescal industries, to obtain a product of high commercial value such as activated carbon. The activated carbon production methodology was based on a chemical activation, by using ZnCl 2 and H 3 PO 4 as activating agent and agave bagasse as a natural source of carbon. The activation temperature (150-450 o C), activation time (0-60 min) and weight ratio of activating agent to precursor (0.2-4) were studied. The produced carbon materials were characterized by scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and nitrogen physisorption at -196 o C. In addition, the activating agent recovery was evaluated. We were able to obtain highly microporous activated carbons with micropore volumes between 0.24 and 1.20 cm 3 /g and a surface area within 300 and 2139 m 2 /g. These results demonstrated the feasibility to treat the industrial wastes of the Tequila and Mescal industries, being this wastes an excellent precursor to produce highly microporous activated carbons that can be processed at low activation temperatures in short times, with the possibility of recycling the activating agent.

  9. Effect of azithromycin on enhancement of methane production from waste activated sludge.

    Science.gov (United States)

    Nguyen, Minh Tuan; Maeda, Toshinari; Mohd Yusoff, Mohd Zulkhairi; Ogawa, Hiroaki I

    2014-07-01

    In the methane production from waste activated sludge (WAS), complex bacterial interactions in WAS have been known as a major contribution to methane production. Therefore, the influence of bacterial community changes toward methane production from WAS was investigated by an application of antibiotics as a simple means for it. In this study, azithromycin (Azm) as an antibiotic was mainly used to observe the effect on microbial changes that influence methane production from WAS. The results showed that at the end of fermentation, Azm enhanced methane production about twofold compared to control. Azm fostered the growth of acid-producing bacterial communities, which synthesized more precursors for methane formation. DGGE result showed that the hydrolysis as well as acetogenesis stage was improved by the dominant of B1, B2 and B3 strains, which are Clostridium species. In the presence of Azm, the total population of archaeal group was increased, resulting in higher methane productivity achievement.

  10. Nanocapsular Dispersion of Cinnamaldehyde for Enhanced Inhibitory Activity against Aflatoxin Production by Aspergillus flavus

    Directory of Open Access Journals (Sweden)

    Hongbo Li

    2015-04-01

    Full Text Available Cinnamaldehyde (CA is marginally soluble in water, making it challenging to evenly disperse it in foods, and resulting in lowered anti-A. flavus efficacy. In the present study, nano-dispersed CA (nano-CA was prepared to increase its aqueous solubility. Free and nano-dispersed CA were compared in terms of their inhibitory activity against fungal growth and aflatoxin production of A. flavus both in Sabouraud Dextrose (SD culture and in peanut butter. Our results indicated that free CA inhibited the mycelia growth and aflatoxin production of A. flavus with a minimal inhibitory concentration (MIC value of 1.0 mM, but promoted the aflatoxin production at some concentrations lower than the MIC. Nano-CA had a lower MIC value of 0.8 mM against A. flavus, and also showed improved activity against aflatoxin production without the promotion at lower dose. The solidity of peanut butter had an adverse impact on the antifungal activity of free CA, whereas nano-dispersed CA showed more than 2-fold improved activity against the growth of A. flavus. Free CA still promoted AFB1 production at the concentration of 0.25 mM, whereas nano-CA showed more efficient inhibition of AFB1 production in the butter.

  11. Development, Implementation and Experimental Validations of Activation Products Models for Water Pool Reactors

    International Nuclear Information System (INIS)

    Petriw, S.N.

    2001-01-01

    Some parameters were obtained both calculations and experiments in order to determined the source of the meaning activation products in water pool reactors. In this case, the study was done in RA-6 reactor (Centro Atomico Bariloche - Argentina).In normal operation, neutron flux on core activates aluminium plates.The activity on coolant water came from its impurities activation and meanly from some quantity of aluminium that, once activated, leave the cladding and is transported by water cooling system.This quantity depends of the 'recoil range' of each activation reaction.The 'staying time' on pool (the time that nuclides are circulating on the reactor pool) is another characteristic parameter of the system.Stationary state activity of some nuclides depends of this time.Also, several theoretical models of activation on coolant water system are showed, and their experimental validations

  12. Analysis of inducers of xylanase and cellulase activities production by Ganoderma applanatum LPB MR-56.

    Science.gov (United States)

    Salmon, Denise Naomi Xavier; Spier, Michele Rigon; Soccol, Carlos Ricardo; Vandenberghe, Luciana Porto de Souza; Weingartner Montibeller, Valesca; Bier, Mário César Jucoski; Faraco, Vincenza

    2014-08-01

    This manuscript describes the analysis of the effect of cellulose, carboxymethylcellulose (CMC), xylan, and xylose as inducers of cellulase and xylanase activity production by Ganoderma applanatum MR-56 and the optimization of their production in liquid cultures by statistical methods. The Plackett-Burman screening design was applied to identify the most significant inducers of xylanase and cellulase activities production by G. applanatum MR-56. The most significant effect on xylanase and cellulase activities production was exercised by cellulose, even if xylose and CMC were also effective at some times. The combined effect of cellulose, yeast extract, and pH was analyzed by a 2(3) factorial experimental design with four central points that showed that the maximum tested cellulose (1 % w/v) and yeast extract (5 g L(-1)) concentrations gave the maximum production of xylanase (8.24 U mL(-1)) and cellulase (3.29 U mL(-1)) activity at pH 6 and 4, respectively. These values achieved for cellulase and xylanase activity represent 12-25 fold and 36 fold higher values than the maximum so far reported for other strains of G. applanatum, respectively. Copyright © 2014 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.

  13. Mesure Objective De L'attenuation et De L'effet D'occlusion Des Protecteurs Auditifs a Partir Des Potentiels Evoques Stationnaires et Multiples =

    Science.gov (United States)

    Valentin, Olivier

    Selon l'Organisation mondiale de la sante, le nombre de travailleurs exposes quotidiennement a des niveaux de bruit prejudiciables a leur audition est passe de 120 millions en 1995 a 250 millions en 2004. Meme si la reduction du bruit a la source devrait etre toujours privilegiee, la solution largement utilisee pour lutter contre le bruit au travail reste la protection auditive individuelle. Malheureusement, le port des protecteurs auditifs n'est pas toujours respecte par les travailleurs car il est difficile de fournir un protecteur auditif dont le niveau d'attenuation effective est approprie a l'environnement de travail d'un individu. D'autre part, l'occlusion du canal auditif induit une modification de la perception de la parole, ce qui cree un inconfort incitant les travailleurs a retirer leurs protecteurs. Ces deux problemes existent parce que les methodes actuelles de mesure de l'effet d'occlusion et de l'attenuation sont limitees. Les mesures objectives basees sur des mesures microphoniques intra-auriculaires ne tiennent pas compte de la transmission directe du son a la cochlee par conduction osseuse. Les mesures subjectives au seuil de l'audition sont biaisees a cause de l'effet de masquage aux basses frequences induit par le bruit physiologique. L'objectif principal de ce travail de these de doctorat est d'ameliorer la mesure de l'attenuation et de l'effet d'occlusion des protecteurs auditifs intra-auriculaires. L'approche generale consiste a : (i) verifier s'il est possible de mesurer l'attenuation des protecteurs auditifs grâce au recueil des potentiels evoques stationnaires et multiples (PEASM) avec et sans protecteur auditif (protocole 1), (ii) adapter cette methodologie pour mesurer l'effet d'occlusion induit par le port de protecteur auditifs intra-auriculaires (protocole 2), et (iii) valider chaque protocole par l'intermediaire de mesures realisees sur sujets humains. Les resultats du protocole 1 demontrent que les PEASM peuvent etre utilises pour

  14. Pharmacodynamic Evaluation of the Activities of Six Parenteral Vancomycin Products Available in the United States

    Science.gov (United States)

    Boyne, Michael T.; Patel, Vikram; Huntley, Clayton; Liu, Weiguo; Fikes, Steven; Kurhanewicz, Stephanie; Rodriquez, Jaime; Robbins, Nichole; Brown, David; Baluya, Dodge; Drusano, G. L.

    2014-01-01

    A recent report found that generic parenteral vancomycin products may not have in vivo efficacies equivalent to those of the innovator in a neutropenic murine thigh infection model despite having similar in vitro microbiological activities and murine serum pharmacokinetics. We compared the in vitro and in vivo activities of six of the parenteral vancomycin products available in the United States. The in vitro assessments for the potencies of the vancomycin products included MIC/minimal bactericidal concentration (MBC) determinations, quantifying the impact of human and murine serum on the MIC values, and time-kill studies. Also, the potencies of the vancomycin products were quantified with a biological assay, and the human and mouse serum protein binding rates for the vancomycin products were measured. The in vivo studies included dose-ranging experiments with the 6 vancomycin products for three isolates of Staphylococcus aureus in a neutropenic mouse thigh infection model. The pharmacokinetics of the vancomycin products were assessed in infected mice by population pharmacokinetic modeling. No differences were seen across the vancomycin products with regard to any in vitro evaluation. Inhibitory sigmoid maximal bacterial kill (Emax) modeling of the relationship between vancomycin dosage and the killing of the bacteria in mice in vivo yielded similar Emax and EC50 (drug exposure driving one-half Emax) values for bacterial killing. Further, there were no differences in the pharmacokinetic clearances of the 6 vancomycin products from infected mice. There were no important pharmacodynamic differences in the in vitro or in vivo activities among the six vancomycin products evaluated. PMID:25385113

  15. Enhancing methane production from waste activated sludge using a novel indigenous iron activated peroxidation pre-treatment process.

    Science.gov (United States)

    Zhou, Xu; Wang, Qilin; Jiang, Guangming

    2015-04-01

    Methane production from anaerobic digestion of waste activated sludge (WAS) is limited by the slow hydrolysis rate and/or poor methane potential of WAS. This study presents a novel pre-treatment strategy based on indigenous iron (in WAS) activated peroxidation to enhance methane production from WAS. Pre-treatment of WAS for 30 min at 50mg H2O2/g total solids (dry weight) and pH 2.0 (iron concentration in WAS was 7 mg/g TS) substantially enhanced WAS solubilization. Biochemical methane potential tests demonstrated that methane production was improved by 10% at a digestion time of 16d after incorporating the indigenous iron activated peroxidation pre-treatment. Model-based analysis indicated that indigenous iron activated peroxidation pre-treatment improved the methane potential by 13%, whereas the hydrolysis rate was not significantly affected. The economic analysis showed that the proposed pre-treatment method can save the cost by $112,000 per year in a treatment plant with a population equivalent of 300,000. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Cascading activation from lexical processing to letter-level processing in written word production.

    Science.gov (United States)

    Buchwald, Adam; Falconer, Carolyn

    2014-01-01

    Descriptions of language production have identified processes involved in producing language and the presence and type of interaction among those processes. In the case of spoken language production, consensus has emerged that there is interaction among lexical selection processes and phoneme-level processing. This issue has received less attention in written language production. In this paper, we present a novel analysis of the writing-to-dictation performance of an individual with acquired dysgraphia revealing cascading activation from lexical processing to letter-level processing. The individual produced frequent lexical-semantic errors (e.g., chipmunk → SQUIRREL) as well as letter errors (e.g., inhibit → INBHITI) and had a profile consistent with impairment affecting both lexical processing and letter-level processing. The presence of cascading activation is suggested by lower letter accuracy on words that are more weakly activated during lexical selection than on those that are more strongly activated. We operationalize weakly activated lexemes as those lexemes that are produced as lexical-semantic errors (e.g., lethal in deadly → LETAHL) compared to strongly activated lexemes where the intended target word (e.g., lethal) is the lexeme selected for production.

  17. Methodology assessment of the total beta activity in tobacco and tobacco products and certain results

    International Nuclear Information System (INIS)

    Georgieva, A.; Srentz, A.

    2016-01-01

    The presence of alpha and beta radionuclides in tobacco and tobacco products is a frequently discussed issue. However, any information in publications about them and their presence in tobacco products is too scarce. World Health care Organization monitors the influence of tobacco smoking on human health. In 2003, a Framework Convention on Tobacco Control was accepted with the aim to protect human health, which was signed by 179 countries, including Bulgaria. The first debates on the presence of radionuclides in tobacco products are raised in Moscow in 2014. These were instigated by data on the findings of polonium-210, reported by USA and Russia. The aim of the report is to outline a methodology to detect the presence of beta-active radionuclides in tobacco and its products. Keywords: beta activity, geiger counter, samples with infinite thickness, tobacco samples

  18. Hydrogen bio-production of carbohydrate fermentation by anaerobic activated sludge process

    Energy Technology Data Exchange (ETDEWEB)

    Ren, N.

    1996-12-31

    Hydrogen gas is expected to be one of the most important clean fuel. The production of hydrogen by biotechnology is one of the ways to obtain low-priced hydrogen gas. According to the types of microorganism, the process of hydrogen production could be divided into photosynthetic and fermentative methods. From the viewpoint of the feasibility of industrial production, the fermentative method of hydrogen production will be the main direction of development. The new type of hydrogen production technology of organic wastewater fermentation by anaerobic activated sludge process was advanced. By the use of the continuous hydrogen bio-production reactor developed by authors and the substrates such as molasses, corn starch and powdered sugar, the effects of some operational parameters such as organic loading rate on the hydrogen production rate were studied, and the ethanol type fermentation of carbohydrate in the process of H{sub 2}-producing acidogenic fermentation was discovered. Under optimal conditions, the gas yield was 0.3m{sup 3} gas/ kg influent COD, the H{sub 2} production rate was 0.42-0.47 L H{sub 2} / L - h, and the specific H{sub 2} production rate was 36-40 mL H{sub 2}/g MLVSS {circ} h. There were only H{sub 2} and CO{sub 2} in fermentation gas that was of 45%-49% of H{sub 2} content. The H{sub 2} production process by use of ethanol type fermentation could obtain high-yield hydrogen gas. This hydrogen bio-production technology using anaerobic activated sludge as H{sub 2} producing bacterium was fast to start-up, easy to operate and cheep to produce hydrogen gas.

  19. Production of activated carbons from waste tyres for low temperature NOx control.

    Science.gov (United States)

    Al-Rahbi, Amal S; Williams, Paul T

    2016-03-01

    Waste tyres were pyrolysed in a bench scale reactor and the product chars were chemically activated with alkali chemical agents, KOH, K2CO3, NaOH and Na2CO3 to produce waste tyre derived activated carbons. The activated carbon products were then examined in terms of their ability to adsorb NOx (NO) at low temperature (25°C) from a simulated industrial process flue gas. This study investigates the influence of surface area and porosity of the carbons produced with the different alkali chemical activating agents on NO capture from the simulated flue gas. The influence of varying the chemical activation conditions on the porous texture and corresponding NO removal from the flue gas was studied. The activated carbon sorbents were characterized in relation to BET surface area, micropore and mesopore volumes and chemical composition. The highest NO removal efficiency for the waste tyre derived activated carbons was ∼75% which was obtained with the adsorbent treated with KOH which correlated with both the highest BET surface area and largest micropore volume. In contrast, the waste tyre derived activated carbons prepared using K2CO3, NaOH and Na2CO3 alkali activating agents appeared to have little influence on NO removal from the flue gases. The results suggest problematic waste tyres, have the potential to be converted to activated carbons with NOx removal efficiency comparable with conventionally produced carbons. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Synthesis and Neurotrophic Activity Studies of Illicium Sesquiterpene Natural Product Analogues.

    Science.gov (United States)

    Richers, Johannes; Pöthig, Alexander; Herdtweck, Eberhardt; Sippel, Claudia; Hausch, Felix; Tiefenbacher, Konrad

    2017-03-02

    Neurotrophic natural products hold potential as privileged structures for the development of therapeutic agents against neurodegeneration. However, only a few studies have been conducted to investigate a common pharmacophoric motif and structure-activity relationships (SARs). Here, an investigation of structurally more simple analogues of neurotrophic sesquiterpenes of the illicium family is presented. A concise synthetic route enables preparation of the carbon framework of (±)-Merrilactone A and (±)-Anislactone A/B on a gram scale. This has allowed access to a series of structural analogues by modification of the core structure, including variation of oxidation levels and alteration of functional groups. In total, 15 derivatives of the natural products have been synthesized and tested for their neurite outgrowth activities. Our studies indicate that the promising biological activity can be retained by structurally simpler natural product analogues, which are accessible by a straightforward synthetic route. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Corrosion products, activity transport and deposition in boiling water reactor recirculation systems

    International Nuclear Information System (INIS)

    Alder, H.P.; Buckley, D.; Grauer, R.; Wiedemann, K.H.

    1992-01-01

    The deposition of activated corrosion products in the recirculation loops of Boiling Water Reactors produces increased radiation levels which lead to a corresponding increase in personnel radiation dose during shut down and maintenance. The major part of this dose rate is due to cobalt-60. Based on a comprehensive literature study concerning this theme, it has been attempted to identify the individual stages of the activity build-up and to classify their importance. The following areas are discussed in detail: The origins of the corrosion products and of cobalt-59 in the reactor feedwaters; the consolidation of the cobalt in the fuel pins deposits (activation); the release and transport of cobalt-60; the build-up of cobalt-60 in the corrosion products in the recirculation loops. Existing models of the build-up of circuit radioactivity are discussed and the operating experiences from selected reactors are summarized. 90 refs, figs and tabs

  2. Hybrid cement based on the alkali activation of by-products of coal

    OpenAIRE

    Rivera,Jhonathan F; Mejia,Johanna M; Mejia de Gutierrez,Ruby; Gordillo,Marisol

    2014-01-01

    This study focuses on the production of an alternative cementitious material with low environmental impact through the evaluation of two-coal combustion by-products. Hybrid cements based on the alkali activation of fly ash, (FA) and boiler slag (BS) blend with a proportion of Portland cement (OPC) up to 30% were produced. FA and BS contain an unburned material up to 16%. Response Surface Methodology (RSM) was used to optimize the compressive strength. BS geopolymer achieved high compressive s...

  3. Development of Distinction Method of Production Area of Ginsengs by Using a Neutron Activation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Jin; Chung, Yong Sam; Sun, Gwang Min; Lee, Yu Na; Yoo, Sang Ho [KAERI, Daejeon (Korea, Republic of)

    2010-05-15

    Distinction of production area of Korean ginsengs has been tried by using neutron activation techniques such as an instrumental neutron activation analysis (INAA) and a prompt gamma activation analysis (PGAA). A distribution of elements has varied according to the part of plant clue to the difference of enrichment effect and influence from a soil where the plants have been grown. So correlation study between plants and soil has been an Issue. In this study, the distribution of trace elements within a Korean ginseng was investigated by using an instrumental neutron activation analysis

  4. A Study on an Executive Technique and Activation of Clean Production in Chemical Industry

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Seong Yong; Lee, Hee Seok; Kim, Kang Seok [Korea Environment Institute, Seoul (Korea)

    2000-12-01

    Clean production does not only make the sustainable development possible through preventing the deterioration of the environmental pollution from the expansion of industrialization but also enhance the company's competitiveness. Clean production is required by all industrial fields but is the most important in chemical industry. The Government has made efforts to change the domestic industrial structure to the environmental-friendly structure through developing the research. However, the domestic industry has not yet activated overall except some large companies, which has concretized the activation of clean production. Especially, the medium and small companies are more sluggish due to the inferiority of capital and technology. With recognizing that the main body of clean production is a company, the effort based on the Government and the academic world, without companies' positive, will cannot help being limited in effects. Therefore, it is necessary to trigger the schemes that urge the companies' motivation to show the effects from the support that have concentrated in hardware like technology until now. It seems to be very important that the guidebook for clean production, which a company can easily adopt, is developed and spread. This report provides the guidebook for clean production that managers and engineers can easily understand and approach in a producing field and presents the scheme to promote clean production, for chemical industry that is seriously required clean production. Even if the presented contents are not perfect, they can be applied to the development of the Government's policy and the administrative activities of companies for clean production as a useful data. 53 refs., 5 figs., 30 tabs.

  5. Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B

    Directory of Open Access Journals (Sweden)

    Jacquie L. Harper

    2015-08-01

    Full Text Available In an effort to more accurately define the mechanism of cell death and to establish structure-activity relationship requirements for the marine meroterpenoid alkaloids thiaplidiaquinones A and B, we have evaluated not only the natural products but also dioxothiazine regioisomers and two precursor quinones in a range of bioassays. While the natural products were found to be weak inducers of ROS in Jurkat cells, the dioxothiazine regioisomer of thiaplidiaquinone A and a synthetic precursor to thiaplidiaquinone B were found to be moderately potent inducers. Intriguingly, and in contrast to previous reports, the mechanism of Jurkat cell death (necrosis vs. apoptosis was found to be dependent upon the positioning of one of the geranyl sidechains in the compounds with thiaplidiaquinone A and its dioxothiazine regioisomer causing death dominantly by necrosis, while thiaplidiaquinone B and its dioxothiazine isomer caused cell death via apoptosis. The dioxothiazine regioisomer of thiaplidiaquinone A exhibited more potent in vitro antiproliferative activity against human tumor cells, with NCI sub-panel selectivity towards melanoma cell lines. The non-natural dioxothiazine regioisomers were also more active in antiplasmodial and anti-farnesyltransferase assays than their natural product counterparts. The results highlight the important role that natural product total synthesis can play in not only helping understand the structural basis of biological activity of natural products, but also the discovery of new bioactive scaffolds.

  6. Studies of activation products in the terrestrial environment of three swedish nuclear power stations

    International Nuclear Information System (INIS)

    Ingemansson, T.; Erlandsson, B.; Mattsson, S.

    1982-01-01

    Samples of sewage sludge, lichen (Cladonia alpestris), soil and ground level air have been analysed for activation products released to the atmosphere from the three Swedish nuclear power stations at Simpevarp near Oskarshamn, Ringhals and Barsebaeck. The activity concentration of the activation products in the sludge can be arranged in the following sequence: 60 Co > 65 Zn > 58 Co 54 Mn. There is agreement between the time variation of the activity concentration in the sludge and the reported releases to the air from the power stations. The measured activity ratio 58 Co/ 60 Co in sludge does not significantly differ from that reported in the releases to the air. The activity concentration in sludge sedimented from incoming waste water has been used to get better time resolution than using only digested sludge from the final step of the plant. These studies have shown that the activity concentration of 60 Co increases substantially with the first rain run-off that reaches the sewage plant and then falls off rapidly. Measurements on samples of lichen and underlying soil show that the radioactive cobalt isotopes ( 58 Co and 60 Co) have a short mean residence time in the lichen carpet compared to most fission products present in global fall-out. (author)

  7. Studies of the structure-antioxidant activity relationships and antioxidant activity mechanism of iridoid valepotriates and their degradation products.

    Science.gov (United States)

    Wang, Feifei; Zhang, Yumei; Wu, Shouhai; He, Yi; Dai, Zhong; Ma, Shuangcheng; Liu, Bin

    2017-01-01

    Oxidative stress has been associated with diverse diseases, including obesity, cancer and neurodegeneration. In fact, Valeriana jatamansi Jones (valerian) and its extracts possess strong antioxidant activities that extend their application in clinical practice to the treatment of these illnesses, even though the underlying mechanisms are not well understood. Iridoid valepotriate, a characteristic iridoid ester in valerian with poor chemical stability, possesses considerable antioxidant components. The original compounds and their degradation products have been found to exhibit strong antioxidant activities. However, the relationship between their structure and antioxidant effects and the mechanism underlying their oxidation resistance remain unclear. A forced degradation study using three iridoid valepotriates (valtrate, acevaltrate and 1-β acevaltrate) was performed in this work, and the structures of their degradation products were estimated by TLC-MS and LC-MS. Comparison of the antioxidant activities of the iridoid valepotriates before and after forced degradation revealed that degradation reduced the activities of the iridoid valepotriates in free radical scavenging and cytotoxic and cell apoptosis tests. The results suggested that the oxirane nucleus is important for defining the antioxidant profile of iridoid valepotriate. We uncovered possible mechanisms that could explain the antioxidant activities, including the generation of two hydroxyl groups through intramolecular transfer of an H• from an oxirane ring and a reduction in ROS levels through interactions with GABAergic signalling pathways.

  8. Studies of the structure-antioxidant activity relationships and antioxidant activity mechanism of iridoid valepotriates and their degradation products

    Science.gov (United States)

    Wang, Feifei; Zhang, Yumei; Wu, Shouhai; He, Yi; Dai, Zhong; Liu, Bin

    2017-01-01

    Oxidative stress has been associated with diverse diseases, including obesity, cancer and neurodegeneration. In fact, Valeriana jatamansi Jones (valerian) and its extracts possess strong antioxidant activities that extend their application in clinical practice to the treatment of these illnesses, even though the underlying mechanisms are not well understood. Iridoid valepotriate, a characteristic iridoid ester in valerian with poor chemical stability, possesses considerable antioxidant components. The original compounds and their degradation products have been found to exhibit strong antioxidant activities. However, the relationship between their structure and antioxidant effects and the mechanism underlying their oxidation resistance remain unclear. A forced degradation study using three iridoid valepotriates (valtrate, acevaltrate and 1-β acevaltrate) was performed in this work, and the structures of their degradation products were estimated by TLC-MS and LC-MS. Comparison of the antioxidant activities of the iridoid valepotriates before and after forced degradation revealed that degradation reduced the activities of the iridoid valepotriates in free radical scavenging and cytotoxic and cell apoptosis tests. The results suggested that the oxirane nucleus is important for defining the antioxidant profile of iridoid valepotriate. We uncovered possible mechanisms that could explain the antioxidant activities, including the generation of two hydroxyl groups through intramolecular transfer of an H• from an oxirane ring and a reduction in ROS levels through interactions with GABAergic signalling pathways. PMID:29232391

  9. Determination of Total Arsenic in Seaweed Products by Neutron Activation Analysis

    International Nuclear Information System (INIS)

    Salim, N.; Santoso, M.; Yanuar, A.; Damayanti; Kartawinata, T.G.

    2013-01-01

    Seaweed products are widely consumed as food nowadays. Seaweeds are known to contain arsenic due to their capability to accumulate arsenic from the environment. Arsenic is a known toxic element which naturally occurs in the environment. Ingestion of high levels of arsenic will cause several adverse health effects. Arsenic in food occurs at trace concentrations which require sensitive and selective analysis methods to perform elemental analysis on. Validated neutron activation analysis was used to determine the arsenic contents in seaweed products namely catoni from domestic product and nori from foreign products. The total arsenic concentration in the samples analyzed ranges from 0.79 mg/kg to 30.14 mg/kg with mean concentration 14.39 mg/kg. The estimated exposure to arsenic contributed by the analyzed products is from 0.07% up to 8.54% of the established provisional tolerable daily intake (PTDI) which is still far below the maximum tolerable level. (author)

  10. Modification of powdered activated carbon for the production of carbon nano fibers (CNFs)

    International Nuclear Information System (INIS)

    Ahmed, Y.M.; Al-Mamun, A.; Muyibi, S.A.; Al-Khatib, M.F.R.; Jameel, A.T.; Al-Saadi, M.A.

    2009-01-01

    Full text: In the present work, powdered activated carbon (PAC) was modified and used for the production of carbon nano fibers (CNFs). The modification of PAC was done by the impregnation of nickel on the surface of the activated carbon using the wet impregnation method. Variable weight percentage ratios of the catalyst (nickel) ratio were used. The nano fibers were synthesized on the surface of modified PAC by using the Chemical Vapor Deposition (CVD) method at a temperature of ∼680 degree Celsius for one hour in the presence of acetylene as a carbon source. FESEM, TEM, and TGA were used for the characterization of the product. (author)

  11. Consumer available permanent hair dye products cause major allergic immune activation in an animal model

    DEFF Research Database (Denmark)

    Bonefeld, Charlotte Menne; Larsen, Jeppe Madura; Dabelsteen, Sally

    2010-01-01

    a modified version of the local lymph node assay. The colour gel and developer (oxidant) were tested separately and in combination. Response was measured by ear swelling and cytokine production in ear tissue and serum by enzyme-linked immunosorbent assay. The immune cellular response in the draining lymph......-cell proliferation within the draining lymph nodes. Treatment with the mixture induced at least 20% more skin inflammation, cytokine production and CD4+ T-cell activation compared with the colour gel alone. Conclusions Consumer available PPD-containing permanent hair dyes can be potent and rapid immune activators...

  12. The IAEA activities supporting implementation of best practice in uranium production cycle

    International Nuclear Information System (INIS)

    Slezak, J.

    2010-01-01

    'Full text:' Since the International Atomic Energy Agency's foundation in 1957, the Agency has had an increasing interest in uranium production cycle (UPC) developments. Recent activities cover tasks on uranium geology & deposits, exploration, mining & processing including environmental issues. The two projects titles are (1) Updating uranium resources, supply and demand and nuclear fuel cycle databases and (2) Supporting good practices in the UPC in particular for new countries. Based o the recent experience, one of the new activities is focused at human resources development to improve application of best practice called Uranium Production Cycle Network (UPNet). (author)

  13. Heterologous production of active ribonuclease inhibitor in Escherichia coli by redox state control and chaperonin coexpression

    Directory of Open Access Journals (Sweden)

    Neubauer Peter

    2011-08-01

    Full Text Available Abstract Background Eukaryotic Ribonuclease inhibitor (RI, belonging to the RNH1 family, is distinguished by unique features - a high sensitivity to oxidation due to the large number of reduced cysteins and a high hydrophobicity, which made most production approaches so far unsuccessful or resulted in very low yields. In this work efficient in vivo folding of native RI in the Escherichia coli cytoplasm was obtained by external addition of a reducing agent in tandem with oxygen limitation and overproduction of a molecular chaperonin. After optimisation of the production conditions in the shake flask scale the process was scaled up to high cell densities by applying a glucose limited fed-batch procedure. Results RI production in a T7 RNA polymerase based system results in accumulation of aggregated inactive product in inclusion bodies. Combination of addition of the reductant DTT, low production temperature and coexpression of the chaperonin GroELS resulted in high level production of approximately 25 mg g-1 CDW active RI in E. coli ER2566 pET21b, corresponding to approximately 800 kU g-1 cell wet weight. Further conditional screening under fed-batch-like conditions with the EnBase® technology and scale up into the bioreactor scale resulted in an efficient high cell density glucose and oxygen limited fed-batch process with a final cell dry weight of 25 g L-1 and a total RI yield of app. 625 mg L-1 (volumetric activity of 80,000 kU L-1. The E. coli based production constructs showed a very high robustness. The recombinant culture maintained its productivity despite the combination of the toxic growth conditions, the substrate limited production mode in tandem with a high level expression of several recombinant proteins, the set of molecular chaperonins and the target protein (RI. Conclusions High level production of active RI in E. coli in a T7 RNA polymerase expression system depends on the following factors: (i addition of a reducing agent, (ii

  14. Soil Moisture Active Passive (SMAP) Mission Level 4 Carbon (L4_C) Product Specification Document

    Science.gov (United States)

    Glassy, Joe; Kimball, John S.; Jones, Lucas; Reichle, Rolf H.; Ardizzone, Joseph V.; Kim, Gi-Kong; Lucchesi, Robert A.; Smith, Edmond B.; Weiss, Barry H.

    2015-01-01

    This is the Product Specification Document (PSD) for Level 4 Surface and Root Zone Soil Moisture (L4_SM) data for the Science Data System (SDS) of the Soil Moisture Active Passive (SMAP) project. The L4_SM data product provides estimates of land surface conditions based on the assimilation of SMAP observations into a customized version of the NASA Goddard Earth Observing System, Version 5 (GEOS-5) land data assimilation system (LDAS). This document applies to any standard L4_SM data product generated by the SMAP Project.

  15. Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products.

    Science.gov (United States)

    Myers, Sharon L; Yang, Chun Z; Bittner, George D; Witt, Kristine L; Tice, Raymond R; Baird, Donna D

    2015-05-01

    Use of personal care products is widespread in the United States but tends to be greater among African Americans than whites. Of special concern is the possible hazard of absorption of chemicals with estrogenic activity (EA) or anti-EA (AEA) in these products. Such exposure may have adverse health effects, especially when it occurs during developmental windows (e.g., prepubertally) when estrogen levels are low. We assessed the ethanol extracts of eight commonly used hair and skin products popular among African Americans for EA and AEA using a cell proliferation assay with the estrogen sensitive MCF-7:WS8 cell line derived from a human breast cancer. Four of the eight personal care products tested (Oil Hair Lotion, Extra-dry Skin Lotion, Intensive Skin Lotion, Petroleum Jelly) demonstrated detectable EA, whereas three (Placenta Hair Conditioner, Tea-Tree Hair Conditioner, Cocoa Butter Skin Cream) exhibited AEA. Our data indicate that hair and skin care products can have EA or AEA, and suggest that laboratory studies are warranted to investigate the in vivo activity of such products under chronic exposure conditions as well as epidemiologic studies to investigate potential adverse health effects that might be associated with use of such products.

  16. Clinical research in dermatology: resources and activities associated with a higher scientific productivity.

    Science.gov (United States)

    Molina-Leyva, Alejandro; Descalzo, Miguel A; García-Doval, Ignacio

    2018-03-06

    Clinical research papers and their derived metrics can be useful to assess the scientific production of medical and research centers. Diverse factors are probably associated to differences in scientific production. But there are scarce studies analyzing them. Resources are limited and have to be distributed efficiently. The objective of this study is to explore what resources and activities are potentially associated with a higher scientific productivity. A bibliometric study was performed to obtain information about scientific productivity. Papers included had to meet criteria to be considered clinical research in dermatology, additionally had to be published between the years 2005-2014, had to be included in Pubmed or Embase and had to include a Spanish center of dermatology as the correspondence address. Information about research resources and activities of the year 2015 was gathered by means of an online survey sent to the authors identified in the bibliometric study. The search strategy returned 8617 papers and only 1104 of them (12.81%) met the inclusion criteria. 63 out of 113 centers responded to the survey (55.75%). Factors associated with a higher scientific productivity were: the size of the resident program, the amount of time specifically dedicated to research, a lower clinical workload, and the number of clinical trials performed in the last year. We have demonstrated that some factors are associated with a higher scientific productivity. Residency program, more research staff, clinical workload redistribution and research motivation/initiatives are key strategies that could improve scientific productivity of a center.

  17. Integration of active pharmaceutical ingredient solid form selection and particle engineering into drug product design.

    Science.gov (United States)

    Ticehurst, Martyn David; Marziano, Ivan

    2015-06-01

    This review seeks to offer a broad perspective that encompasses an understanding of the drug product attributes affected by active pharmaceutical ingredient (API) physical properties, their link to solid form selection and the role of particle engineering. While the crucial role of active pharmaceutical ingredient (API) solid form selection is universally acknowledged in the pharmaceutical industry, the value of increasing effort to understanding the link between solid form, API physical properties and drug product formulation and manufacture is now also being recognised. A truly holistic strategy for drug product development should focus on connecting solid form selection, particle engineering and formulation design to both exploit opportunities to access simpler manufacturing operations and prevent failures. Modelling and predictive tools that assist in establishing these links early in product development are discussed. In addition, the potential for differences between the ingoing API physical properties and those in the final product caused by drug product processing is considered. The focus of this review is on oral solid dosage forms and dry powder inhaler products for lung delivery. © 2015 Royal Pharmaceutical Society.

  18. Antimicrobial activity of thin metallic silver flakes, waste products of a manufacturing process.

    Science.gov (United States)

    Anzano, Manuela; Tosti, Alessandra; Lasagni, Marina; Campiglio, Alfredo; Pitea, Demetrio; Collina, Elena

    2011-01-01

    The aim of the research was to develop new products and processes from a manufacturing waste from an Italian metallurgic company. The company produced thin silver metallic films and the production scraps were silver flakes. The possibility to use the silver flakes in water disinfection processes was studied. The antimicrobial activity of the flakes was investigated in batch using Escherichia coli as Gram-negative microorganism model. The flakes did not show any antimicrobial activity, so they were activated with two different processes: thermal activation in reducing atmosphere and chemical activation, obtaining, respectively, reduced flakes (RF) and chemical flakes (CF). The flakes, activated with either treatment, showed antimicrobial activity against E. coli. The kill rate was dependent on the type of activated flakes. The chemical flakes were more efficient than reduced flakes. The kill rate determined for 1 g of CF, 1.0 +/- 0.2 min(-1), was greater than the kill rate determined for 1 g of RF, 0.069 +/- 0.004 min(-1). This was confirmed also by the minimum inhibitory concentration values. It was demonstrated that the antimicrobial capability was dependent on flakes amount and on the type of aqueous medium. Furthermore, the flakes maintained their properties also when used a second time. Finally, the antimicrobial activities of flakes were tested in an effluent of a wastewater treatment plant where a variety of heterotrophic bacteria were present.

  19. Improved Bioethanol Production Using Activated Carbon-treated Acid Hydrolysate from Corn Hull in Pachysolen tannophilus.

    Science.gov (United States)

    Seo, Hyeon-Beom; Kim, Seungseop; Lee, Hyeon-Yong; Jung, Kyung-Hwan

    2009-06-01

    To optimally convert corn hull, a byproduct from corn processing, into bioethanol using Pachysolen tannophlius, we investigated the optimal conditions for hydrolysis and removal of toxic substances in the hydrolysate via activated carbon treatment as well as the effects of this detoxification process on the kinetic parameters of bioethanol production. Maximum monosaccharide concentrations were obtained in hydrolysates in which 20 g of corn hull was hydrolyzed in 4% (v/v) H2SO4. Activated carbon treatment removed 92.3% of phenolic compounds from the hydrolysate. When untreated hydrolysate was used, the monosaccharides were not completely consumed, even at 480 h of culture. When activated carbon-treated hydrolysate was used, the monosaccharides were mostly consumed at 192 h of culture. In particular, when activated carbon-treated hydrolysate was used, bioethanol productivity (P) and specific bioethanol production rate (Qp) were 2.4 times and 3.4 times greater, respectively, compared to untreated hydrolysate. This was due to sustained bioethanol production during the period of xylose/arabinose utilization, which occurred only when activated carbon-treated hydrolysate was used.

  20. Activation of Protease-Activated Receptor 2-Mediated Signaling by Mast Cell Tryptase Modulates Cytokine Production in Primary Cultured Astrocytes

    Directory of Open Access Journals (Sweden)

    Xiaoning Zeng

    2013-01-01

    Full Text Available Protease-activated receptor 2 (PAR-2, which is abundantly expressed in astrocytes, is known to play major roles in brain inflammation. However, the influence of the natural agonist of PAR-2, tryptase, on proinflammatory mediator releasedfrom astrocytes remains uninvestigated. In the present study, we found that tryptase at lower concentrations modestly reduced intracellular ROS production but significantly increased IL-6 and TNF-α secretion at higher concentrations without affecting astrocytic viability and proliferation. The actions of tryptase were alleviated by specific PAR-2 antagonist FSLLRY-NH2 (FS, indicating that the actions of tryptase were via PAR-2. PI3K/AKT inhibitor LY294002 reversed the effect of tryptase on IL-6 production, whereas inhibitors specific for p38, JNK, and ERK1/2 abolished the effect of tryptase on TNF-α production, suggesting that different signaling pathways are involved. Moreover, tryptase-induced activation of MAPKs and AKT was eliminated by FS, implicating that PAR-2 is responsible for transmitting tryptase biosignals to MAPKs and AKT. Tryptase provoked also expression of TGF-β and CNTF in astrocytes. The present findings suggest for the first time that tryptase can regulate the release of cytokines from astrocytes via PAR-2-MAPKs or PAR-2-PI3K/AKT signaling pathways, which reveals PAR-2 as a new target actively participating in the regulation of astrocytic functions.

  1. Factors affecting release of ethanol vapour in active modified atmosphere packaging systems for horticultural products

    Directory of Open Access Journals (Sweden)

    Weerawate Utto

    2014-04-01

    Full Text Available The active modified atmosphere packaging (active MAP system , which provides interactive postharvest control , using ethanol vapour controlled release, is one of the current interests in the development of active packaging for horticultural products. A number of published research work have discussed the relationship between the effectiveness of ethanol vapour and its concentration in the package headspace, including its effect on postharvest decay and physiological controls. This is of importance because a controlled release system should release and maintain ethanol vapour at effective concentrations during the desired storage period. A balance among the mass transfer processes of ethanol vapour in the package results in ethanol vapour accumulation in the package headspace. Key factors affecting these processes include ethanol loading, packaging material, packaged product and storage environment (temperature and relative h umidity. This article reviews their influences and discusses future work required to better understand their influences on ethanol vapour release and accumulations in active MAP.

  2. Macrophage activation induced by Brucella DNA suppresses bacterial intracellular replication via enhancing NO production.

    Science.gov (United States)

    Liu, Ning; Wang, Lin; Sun, Changjiang; Yang, Li; Tang, Bin; Sun, Wanchun; Peng, Qisheng

    2015-12-01

    Brucella DNA can be sensed by TLR9 on endosomal membrane and by cytosolic AIM2-inflammasome to induce proinflammatory cytokine production that contributes to partially activate innate immunity. Additionally, Brucella DNA has been identified to be able to act as a major bacterial component to induce type I IFN. However, the role of Brucella DNA in Brucella intracellular growth remains unknown. Here, we showed that stimulation with Brucella DNA promote macrophage activation in TLR9-dependent manner. Activated macrophages can suppresses wild type Brucella intracellular replication at early stage of infection via enhancing NO production. We also reported that activated macrophage promotes bactericidal function of macrophages infected with VirB-deficient Brucella at the early or late stage of infection. This study uncovers a novel function of Brucella DNA, which can help us further elucidate the mechanism of Brucella intracellular survival. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Phytase Activity of Lactic Acid Bacteria Isolated from Dairy and Pharmaceutical Probiotic Products

    Directory of Open Access Journals (Sweden)

    Zohreh Khodaii

    2013-01-01

    Full Text Available Phytate, the major storage form of phosphorus in plant seeds, can form insoluble complexes with minerals such as iron, zinc and calcium thus reducing their bioavailability. Phytase enzymes are often used to upgrade the nutritional quality of phytate-rich foods and feeds such as grains. The phytate-degrading activity of 43 lactic acid bacteria including isolates from commercial probiotic preparations, dairy products and type strains were measured. The phytate-degrading activity of bifidobacteria and lactobacillus isolates from pharmaceutical probiotics, dairy products and type strains were determined. The enzyme activity of probotic bacteria ranged between 1.1-5.4 mU and was strain not species specific. Phytase activity may thus be a useful additional attribute of probiotics to be used as food supplements.

  4. Improved Bioethanol Production Using Activated Carbon-treated Acid Hydrolysate from Corn Hull in Pachysolen tannophilus

    OpenAIRE

    Seo, Hyeon-Beom; Kim, Seungseop; Lee, Hyeon-Yong; Jung, Kyung-Hwan

    2009-01-01

    To optimally convert corn hull, a byproduct from corn processing, into bioethanol using Pachysolen tannophlius, we investigated the optimal conditions for hydrolysis and removal of toxic substances in the hydrolysate via activated carbon treatment as well as the effects of this detoxification process on the kinetic parameters of bioethanol production. Maximum monosaccharide concentrations were obtained in hydrolysates in which 20 g of corn hull was hydrolyzed in 4% (v/v) H2SO4. Activated carb...

  5. Consensus Modeling for Prediction of Estrogenic Activity of Ingredients Commonly Used in Sunscreen Products

    Directory of Open Access Journals (Sweden)

    Huixiao Hong

    2016-09-01

    Full Text Available Sunscreen products are predominantly regulated as over-the-counter (OTC drugs by the US FDA. The “active” ingredients function as ultraviolet filters. Once a sunscreen product is generally recognized as safe and effective (GRASE via an OTC drug review process, new formulations using these ingredients do not require FDA review and approval, however, the majority of ingredients have never been tested to uncover any potential endocrine activity and their ability to interact with the estrogen receptor (ER is unknown, despite the fact that this is a very extensively studied target related to endocrine activity. Consequently, we have developed an in silico model to prioritize single ingredient estrogen receptor activity for use when actual animal data are inadequate, equivocal, or absent. It relies on consensus modeling to qualitatively and quantitatively predict ER binding activity. As proof of concept, the model was applied to ingredients commonly used in sunscreen products worldwide and a few reference chemicals. Of the 32 chemicals with unknown ER binding activity that were evaluated, seven were predicted to be active estrogenic compounds. Five of the seven were confirmed by the published data. Further experimental data is needed to confirm the other two predictions.

  6. New approaches to estimation of peat deposits for production of biologically active compounds

    Science.gov (United States)

    Stepchenko, L. M.; Yurchenko, V. I.; Krasnik, V. G.; Syedykh, N. J.

    2009-04-01

    It is known, that biologically active preparations from peat increase animals productivity as well as resistance against stress-factors and have adaptogeneous, antioxidant, immunomodulative properties. Optymal choice of peat deposits for the production of biologically active preparations supposes the detailed comparative analysis of peat properties from different deposits. For this the cadastre of peat of Ukraine is developed in the humic substances laboratory named after prof. Khristeva L.A. (Dnipropetrovsk Agrarian University, Ukraine). It based on the research of its physical and chemical properties, toxicity and biological activity, and called Biocadastre. The Biocadastre is based on the set of parameters, including the descriptions of physical and chemical properties (active acidity, degree of decomposition, botanical composition etc.), toxicity estimation (by parabyotyc, infusorial, inhibitor and other tests), biological activity indexes (growth-promoting, antioxidative, adaptogeneous, immunomodulative antistress and other actions). The blocks of Biocadastre indexes are differentiated, taking into account their use for creation the preparations for vegetable, animals and microorganisms. The Biocadastre will allow to choose the peat deposits, most suitable for the production of different biologically active preparations, both wide directed and narrow spectrum of action, depending on application fields (medicine, agriculture, veterinary medicine, microbiological industry, balneology, cosmetology).

  7. YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Tsong-Long, E-mail: htl@mail.cgu.edu.tw [Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan (China); Chinese Herbal Medicine Research Team, Healthy Aging Research Center, Chang Gung University, Kweishan, Taoyuan, Taiwan (China); Tang, Ming-Chi [Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan (China); Kuo, Liang-Mou [Department of General Surgery, Chang Gung Memorial Hospital at Chia-Yi, Taiwan (China); Chang, Wen-De; Chung, Pei-Jen; Chang, Ya-Wen; Fang, Yao-Ching [Graduate Institute of Natural Products, College of Medicine, Chang Gung University, Taoyuan, Taiwan (China)

    2012-04-15

    Alveolar macrophages play significant roles in the pathogenesis of several inflammatory lung diseases. Increases in exhaled nitric oxide (NO) are well documented to reflect disease severity in the airway. In this study, we investigated the effect of 3-(5′-hydroxymethyl-2′-furyl)-1-benzyl indazole (YC-1), a known activator of soluble guanylyl cyclase, on prostaglandin (PG)E{sub 1} (a stable PGE{sub 2} analogue) and forskolin (a adenylate cyclase activator) induced NO production and inducible NO synthase (iNOS) expression in rat alveolar macrophages (NR8383). YC-1 did not directly cause NO production or iNOS expression, but drastically potentiated PGE{sub 1}- or forskolin-induced NO production and iNOS expression in NR8383 alveolar macrophages. Combination treatment with YC-1 and PGE{sub 1} significantly increased phosphorylation of the cAMP response element-binding protein (CREB), but not nuclear factor (NF)-κB activation. The combined effect on NO production, iNOS expression, and CREB phosphorylation was reversed by a protein kinase (PK)A inhibitor (H89), suggesting that the potentiating functions were mediated through a cAMP/PKA signaling pathway. Consistent with this, cAMP analogues, but not the cGMP analogue, caused NO release, iNOS expression, and CREB activation. YC-1 treatment induced an increase in PGE{sub 1}-induced cAMP formation, which occurred through the inhibition of cAMP-specific phosphodiesterase (PDE) activity. Furthermore, the combination of rolipram (an inhibitor of PDE4), but not milronone (an inhibitor of PDE3), and PGE{sub 1} also triggered NO production and iNOS expression. In summary, YC-1 potentiates PGE{sub 1}-induced NO production and iNOS expression in alveolar macrophages through inhibition of cAMP PDE activity and activation of the cAMP/PKA/CREB signaling pathway. Highlights: ► YC-1 potentiated PGE1-induced iNOS expression in alveolar macrophages. ► The combination of YC-1 and PGE1 increased CREB but not NFκB activation.

  8. Effect of Tityus serrulatus venom on cytokine production and the activity of murine macrophages

    Directory of Open Access Journals (Sweden)

    Vera L. Petricevich

    2002-01-01

    Full Text Available The purpose of this study was to investigate the effects of Tityus serrulatus venom (TSV on murine peritoneal macrophages evaluated in terms of activation. The effects of crude TSV were analysed by detection of cytokines, oxygen intermediate metabolites (H2O2 and nitric oxide (NO in supernatants of peritoneal macrophages. Several functional bioassays were employed including an in vitro model for envenomating: cytotoxicity of TSV was assessed using the lyses percentage. Tumor necrosis factor (TNF activity was assayed by measuring its cytotoxic activity on L-929 cells, and interleukin-6 (IL-6 and interferon-γ (IFN-γ were assayed by enzyme-linked immunosorbent assay, whereas NO levels were detected by Griess colorimetric reactions in culture supernatant of macrophages incubated with TSV and subsequently exposed to either lipopolysaccharide or IFN-γ. Incubation of macrophages with TSV increased production of IL-6 and IFN-γ in a dose-dependent manner. TNF production was not detected in supernatants treated with TSV at any concentration. The increase in IL-6 secretion was not associated with concentration-dependent cytoxicity of TSV on these cells. These data suggest that the cytotoxicity does not appear to be the main cause of an increased cytokine production by these cells. Although NO is an important effector molecule in macrophage microbicidal activity, the inducing potential of the test compounds for its release was found to be very moderate, ranging from 125 to 800 mM. Interestingly, NO levels of peritoneal macrophages were increased after IFN-γ. Moreover, NO production had an apparent effect on macrophage activity. The results obtained here also shown that the TSV induces an important elevation in H2O2 release. These results combined with NO production suggest that TSV possesses significant immunomodulatory activities capable of stimulating immune functions in vitro.

  9. ON THE NON-KOLMOGOROV NATURE OF FLARE-PRODUCTIVE SOLAR ACTIVE REGIONS

    Energy Technology Data Exchange (ETDEWEB)

    Mandage, Revati S. [Physics and Astronomy Department, Rice University, 6100 Main MS-61, Houston, TX 77005-1827 (United States); McAteer, R. T. James, E-mail: mcateer@nmsu.edu [Department of Astronomy, New Mexico State University, MSC 4500, Las Cruces, NM 88001 (United States)

    2016-12-20

    A magnetic power spectral analysis is performed on 53 solar active regions, observed from 2011 August to 2012 July. Magnetic field data obtained from the Helioseismic and Magnetic Imager, inverted as Active Region Patches, are used to study the evolution of the magnetic power index as each region rotates across the solar disk. Active regions are classified based on the numbers and sizes of solar flares they produce in order to study the relationship between flare productivity and the magnetic power index. The choice of window size and inertial range plays a key role in determining the correct magnetic power index. The overall distribution of magnetic power indices has a range of 1.0–2.5. Flare-quiet regions peak at a value of 1.6. However, flare-productive regions peak at a value of 2.2. Overall, the histogram of the distribution of power indices of flare-productive active regions is well separated from flare-quiet active regions. Only 12% of flare-quiet regions exhibit an index greater than 2, whereas 90% of flare-productive regions exhibit an index greater than 2. Flare-quiet regions exhibit a high temporal variance (i.e., the index fluctuates between high and low values), whereas flare-productive regions maintain an index greater than 2 for several days. This shows the importance of including the temporal evolution of active regions in flare prediction studies, and highlights the potential of a 2–3 day prediction window for space weather applications.

  10. Mesure des fluctuations de température dans un résonateur équipant un système thermoacoustique

    OpenAIRE

    Poignand , Gaëlle; Berson , Arganthaël; Blanc Benon , Philippe; Comte-Bellot , Geneviève; Jondeau , Emmanuel

    2010-01-01

    National audience; Dans les systèmes thermoacoustiques, les fluctuations de température présentent un caractère fortement non-linéaire aux extrémités du stack. La connaissance de ces fluctuations est essentielle dans la détermination et l'optimisation des transferts de chaleur entre le stack et les échangeurs de chaleur et demande la mise au point de nouvelles méthodes de mesure. Cette étude présente une méthode de mesures des fluctuations de température le long d'un résonateur thermoacoustiq...

  11. Michel Ledoux - Isopérimétrie dans les espaces métriques mesurés : Colloquium MathAlp 2016

    OpenAIRE

    Ledoux , Michel; Bastien , Fanny

    2016-01-01

    Le problème isopérimétrique (à volume donné, minimiser la mesure de bord, et déterminer les ensembles extrémaux), remonte aux temps les plus anciens. Tout à la fois, il peut se formuler de façon générale dans un espace métrique mesuré, et dans le même temps assez peu d’exemples explicites, en particuliers de minimiseurs, sont connus. Les questions se portent ainsi vers des propriétés de comparaison avec les des espaces modèles, comme ceux de la géométrie, euclidienne, sphérique et hyperboliqu...

  12. Effect of ph and temperature on the activity of phytase products used in broiler nutrition

    Directory of Open Access Journals (Sweden)

    L de P Naves

    2012-09-01

    Full Text Available The activity of three commercial microbial phytase (Aspergillus oryzae, A. niger, and Saccharomyces cerevisae products used in broiler nutrition was determined at different pH (2.0 to 9.0 and temperature (20 to 90°C values. Enzymatic activity was determined according to the reaction of the phytase with its substrate (sodium phytate, in four replicates, and was expressed in units of phytase activity (FTU. A. oryzae phytase exhibited optimal activity at pH 4.0 and 40°C, but its absolute activity was the lowest of the three phytases evaluated. A. niger phytase exhibited maximal activity close to pH 5.0 and 45ºC, whereas S. cerevisae phytase presented its highest activity at pH close to 4.5 and temperatures ranging between 50 and 60°C. It was concluded that A. niger and S. cerevisae phytase products exhibited the highest absolute activities in vitro at pH and temperature values (pH lower than 5.0 and 41ºC corresponding to the ideal physiological conditions of broilers, which would theoretically allow high hydrolysis rate of the phytate contained in the feed.

  13. Characterization of Co-Cultivation of Cyanobacteria on Growth, Productions of Polysaccharides and Extracellular Proteins, Nitrogenase Activity, and Photosynthetic Activity.

    Science.gov (United States)

    Xue, Chuizhao; Wang, Libo; Wu, Tong; Zhang, Shiping; Tang, Tao; Wang, Liang; Zhao, Quanyu; Sun, Yuhan

    2017-01-01

    Cyanobacteria as biofertilizers are benefit to reduce the use of chemical fertilizers and reestablish the ecological system in soil. In general, several strains of cyanobacteria were involved in the biofertilizers. The co-cultivation of cyanobacteria were characterized on growth profile, production of polysaccharides and extracellular proteins, nitrogenase activity, and photosynthetic activity for three selected N 2 -fixing cyanobacteria, Anabaena cylindrica (B1611 and F243) and Nostoc sp. (F280). After eight-day culture, the highest dry weights were obtained in F280 pure culture and co-cultivation of B1611 and F280. Higher production of extracellular proteins and cell-bonding polysaccharides (CPS) were observed in co-cultivations compared with pure culture. The highest released polysaccharides (RPS) contents were obtained in pure culture of F280 and co-cultivation of F280 and F243. Galactose and glucose were major components of CPS and RPS in all samples. Trehalose was a specific component of RPS in F280 pure culture. Based on the monosaccharide contents of CPS and RPS, F280 was the dominant species in the related treatments of co-cultivation. The nitrogenase activities in all treatments exhibited a sharp rise at the late stage while a significant decrease existed when three cyanobacteria strains were mixed. Photosynthetic activities for all treatments were determined with rapid light curve, and the related parameters were estimated.

  14. Studies on Possible Activation of Microbial Laccase Production Using Gamma Irradiation

    International Nuclear Information System (INIS)

    ElKenawy, N.M.A.

    2013-01-01

    Enzyme production is an essential discipline in biotechnology. Laccase enzyme is an oxidoreductase that catalyzes the oxidation of various aromatic compounds, with the simultaneous reduction of oxygen into water. Although the enzyme is present in plants, insects and bacteria, the most important source is fungi and particularly the Basidiomycetes. In fungi, the enzyme plays a role in the removal of potentially toxic phenols arising during fungal morphogenesis, sporulation, phytopathogensis and virulence. In this work, the production of fungal laccase was optimized from a local isolate of Pleurotus ostreatus using solid state fermentation. Factorial design was used to study the effect of several nutrients and inducer on enzyme activity. Purification, characterization of the enzyme, the effect of temperature and ph were studied. The effect of gamma radiation on fungal growth and enzyme production was investigated. The optimization of the production conditions yielded an enzyme with activity over 32,054 IU/gram of fermented substrate. Factorial design was capable of establishing the conditions that multiplied the activity of the enzyme several folds and consequently, reducing the cost of production. The enzyme was capable of decolorizing several dyes with over 80 % reduction in color in case of methyl orange and trypan blue. The decolorisation of dyes is a simple method to assess the aromatic degrading capability of laccase. The enzyme was also used in the synthesis of gold nanoparticles, proving that laccase from Pleurotus ostreatus has a strong potential in several industrial applications, which opens a door towards using of fungal laccase in further biotechnological processes.

  15. Virtual screening on natural products for discovering active compounds and target information.

    Science.gov (United States)

    Shen, Jianhua; Xu, Xiaoying; Cheng, Feng; Liu, Hong; Luo, Xiaomin; Shen, Jingkang; Chen, Kaixian; Zhao, Weimin; Shen, Xu; Jiang, Hualiang

    2003-11-01

    Natural products, containing inherently large-scale structural diversity than synthetic compounds, have been the major resources of bioactive agents and will continually play as protagonists for discovering new drugs. However, how to access this diverse chemical space efficiently and effectively is an exciting challenge for medicinal chemists and pharmacologists. While virtual screening, which has shown a great promise in drug discovery, will play an important role in digging out lead (active) compounds from natural products. This review focuses on the strategy of virtual screening based on molecular docking and, with successful examples from our laboratory, illustrates the efficiency of virtual screening in discovering active compounds from natural products. On the other hand, the sequencing of the human genome and numerous pathogen genomes has resulted in an unprecedented opportunity for discovering potential new drug targets. Chemogenomics has appeared as a new technology to initiate target discovery by using active compounds as probes to characterize proteome functions. Natural products are the ideal probes for such research. Binding affinity fingerprint is a powerful chemogenomic descriptor to characterize both small molecules and pharmacologically relevant proteins. Therefore, this review also discusses binding affinity fingerprint strategy for identifying target information from the genomic data by using natural products as the probes.

  16. Influence of water activity, temperature and time on mycotoxins production on barley rootlets.

    Science.gov (United States)

    Ribeiro, J M M; Cavaglieri, L R; Fraga, M E; Direito, G M; Dalcero, A M; Rosa, C A R

    2006-02-01

    The objective of this study was to determine the ochratoxin (OT) and aflatoxin (AF) production by three strains of Aspergillus spp. under different water activities, temperature and incubation time on barley rootlets (BR). Aspergillus ochraceus and Aspergillus flavus were able to produce mycotoxins on BR. Aspergillus ochraceus produced ochratoxin A (OTA) at 0.80 water activity (a(w)), at 25 and 30 degrees C as optimal environmental conditions. The OTA production varies at different incubation days depending on a(w). Aflatoxin B(1) (AFB1) accumulation was obtained at 25 degrees C, at 0.80 and 0.95 a(w), after 14 and 21 incubation days respectively. Temperature was a critical factor influencing OTA and AFB(1) production. This study demonstrates that BR support OTA and AFB(1) production at relatively low water activity (0.80 a(w)) and high temperatures (25-30 degrees C). The study of ecophysiological parameters and their interactions would determine the prevailing environmental factors, which enhance the mycotoxin production on BR used as animal feed.

  17. Advertisements for children's entertainment products in a popular parenting magazine: sedentary or active?

    Science.gov (United States)

    Basch, Corey H; Kecojevic, Aleksandar; Cadorett, Valerie; Basch, Charles E

    2017-01-01

    Background: The purpose of this study was to describe advertisements of children's entertainment products in a popular magazine, Parents, and to determine if they illustrated behavior that was physically active or sedentary. Methods: The sample was comprised of Parents magazines (January 2010 to December 2015). Coding involved determining if the advertisement was promoting sedentary or active behavior. Results: Nearly all of the 169 advertisements in the sample (n = 166; 97.6%) were for products that depicted sedentary behavior. The most common types of entertainment products advertised were DVDs (n = 72), plastic stacking products (n = 18), books (n=14), and electronic devices (n = 13). The most popular theme that appeared in the advertisements was the entertainment product would enhance intelligence (n = 85; 50.3%, 95% CI: 0.43-0.58). The overwhelming majority (n = 136; 80.5%. 95% CI: 0.76-0.87) of the advertisements involved the presence of a character. Conclusion: This type of advertising does not contribute to the nation's goals of increasing physical activity among youth.

  18. Application industrielle de ITIRM pour visualiser et mesurer la qualité de surface lors de la fabrication de composants optiques de haute qualité

    NARCIS (Netherlands)

    Bijl, R.J.M. van der; Fähnle, O.W.; Brug, H. van; Debruyne, S.; Braat, J.J.M.

    2000-01-01

    iTIRM est une nouvelle méthode quantitative pour mesurer la qualité de surface des composants optiques. A cause de son caractère non destructif, il est possible d'utiliser iTIRM pour contrôler la qualité de surface lors des procédés de doucissage et de polissage. Par conséquent, iTIRM est un outil

  19. Mesures de procédure spéciales et respect des droits de l'homme Rapport général

    NARCIS (Netherlands)

    Vervaele, J.A.E.

    2009-01-01

    Le but du rapport général est de mener une analyse comparative des rapports nationaux en vue de présenter les processus de transformation des systèmes de justice pénale internes, en particulier du procès pénal, étant donné que des mesures procédurales spéciales sont introduites pour appréhender le

  20. Contribution of activation products to occupational exposure following treatment using high-energy photons in radiotherapy

    International Nuclear Information System (INIS)

    Petrovic, N.; Krestic-Vesovic, J.; Stojanovic, D.; Ciraj-Bjelac, O.; Lazarevic, D.; Kovacevic, M.

    2011-01-01

    When high-energy photon beams are used for irradiation in radiotherapy, neutrons that are the result of photonuclear reactions create activation products that affect the occupational dose of radiotherapy staff. For the assessment of activation products in situ gamma spectroscopy was performed parallel to dose-rate measurements following irradiation, by using a high-energy photon beam from a linear accelerator Elekta Precise (Elekta, Stockholm (Sweden)) used in radiotherapy. The major identified activation products were the following radioisotopes: 2 '8Al, 24 Na, 56 Mn, 5 4 M n, 187 W, 64 Cu and 62 Cu. Based on the typical workload and dose-rate measurement, the assessed additional annual occupational dose ranged from 1.7 to 0.25 mSv. As the measured dose rate arising from the activation products rapidly decreases as a function of time, the assessed additional dose is negligible after 10 min following irradiation. To keep the occupational dose as low as reasonably achievable, it is recommended to delay entrance to the therapy room at least 2-4 min, when high-energy photons are used. This would reduce the effective dose by 30 %. (authors)

  1. Predicting the initial freezing point and water activity of meat products from composition data

    NARCIS (Netherlands)

    Sman, van der R.G.M.; Boer, E.P.J.

    2005-01-01

    In this paper we predict the water activity and initial freezing point of food products (meat and fish) based on their composition. The prediction is based on thermodynamics (the Clausius-Clapeyron equation, the Ross equation and an approximation of the Pitzer equation). Furthermore, we have taken

  2. 77 FR 74170 - Foreign-Trade Zone 84-Houston, TX; Notification of Proposed Production Activity; Mitsubishi...

    Science.gov (United States)

    2012-12-13

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-88-2012] Foreign-Trade Zone 84--Houston, TX...); Houston, TX The Port of Houston Authority, grantee of FTZ 84, submitted a notification of proposed production activity on behalf of Mitsubishi Caterpillar Forklift America Inc. (MCFA), located in Houston...

  3. Learning as the Construction and Re-Mediation of Activity Systems: Environmental Management in Biogas Production

    Science.gov (United States)

    Pereira Querol, Marco A.; Suutari, Timo; Seppanen, Laura

    2010-01-01

    The purpose of this paper is to present theoretical tools for understanding the dynamics of change and learning during the emergence and development of environmental management activities. The methodology consists of a historical analysis of a case of biogas production that took place in the Southwest region of Finland. The theoretical tools used…

  4. Cross-Language Activation in Children's Speech Production: Evidence from Second Language Learners, Bilinguals, and Trilinguals

    Science.gov (United States)

    Poarch, Gregory J.; van Hell, Janet G.

    2012-01-01

    In five experiments, we examined cross-language activation during speech production in various groups of bilinguals and trilinguals who differed in nonnative language proficiency, language learning background, and age. In Experiments 1, 2, 3, and 5, German 5- to 8-year-old second language learners of English, German-English bilinguals,…

  5. Neutron activation analysis of zinc in forages used in intensive dairy cattle production systems

    International Nuclear Information System (INIS)

    Armelin, M.J.A.; Piasentin, R.M.; Primavesi, O.

    2002-01-01

    Instrumental neutron activation analysis (INAA) was applied for the determination of Zn concentration in the main tropical grass forages used in intensive dairy cattle production systems, in Brazil. Smaller Zn concentration could be verified in the rainy period. Comparison of results obtained in these analyses of forages dry matter with daily requirements pointed towards deficiency of Zn in the forages. (author)

  6. 77 FR 55455 - Foreign-Trade Zone 235-Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence...

    Science.gov (United States)

    2012-09-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 235--Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence Innovations, LLC, (Fragrance Bottling), Holmdel, NJ Cosmetic Essence Innovations, LLC (CEI...

  7. 77 FR 26737 - Foreign-Trade Zone 235-Lakewood, NJ: Notification of Proposed Production Activity; Cosmetic...

    Science.gov (United States)

    2012-05-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 235--Lakewood, NJ: Notification of Proposed Production Activity; Cosmetic Essence Innovations, LLC (Fragrance Bottling); Holmdel, NJ Cosmetic Essence Innovations...

  8. 78 FR 24158 - Foreign-Trade Zone (FTZ) 75-Phoenix, Arizona; Notification of Proposed Production Activity...

    Science.gov (United States)

    2013-04-24

    ...; polyethylene films (ballotini); insulation (kapton) films; thermal isolator washers; articles of rubber (rings...(b), FTZ activity would be limited to the specific foreign-status materials and components and... the foreign status materials and components used in export production. On its domestic sales, OSC...

  9. Cross-language activation in children's speech production: Evidence from second language learners, bilinguals, and trilinguals

    NARCIS (Netherlands)

    Poarch, G.J.; Hell, J.G. van

    2012-01-01

    In five experiments, we examined cross-language activation during speech production in various groups of bilinguals and trilinguals who differed in nonnative language proficiency, language learning background, and age. In Experiments 1, 2, 3, and 5, German 5- to 8-year-old second language learners

  10. 78 FR 70532 - Notification of Proposed Production Activity, Hitachi Automotive Systems Americas, Inc., Subzone...

    Science.gov (United States)

    2013-11-26

    ... Activity, Hitachi Automotive Systems Americas, Inc., Subzone 29F, (Automotive Electric-Hybrid Drive System... products (lithium-ion hybrid battery pack assemblies, electrical power steering modules, and electronic... hybrid battery pack assemblies, rotors A&B, stators A&B, electrical power steering modules, and...

  11. Effect of eosinophils activated with Alternaria on the production of extracellular matrix from nasal fibroblasts.

    Science.gov (United States)

    Shin, Seung-Heon; Ye, Mi-Kyung; Choi, Sung-Yong; Kim, Yee-Hyuk

    2016-06-01

    Eosinophils and fibroblasts are known to play major roles in the pathogenesis of nasal polyps. Fungi are commonly found in nasal secretion and are associated with airway inflammation. To investigate whether activated eosinophils by airborne fungi can influence the production of extracellular matrix (ECM) from nasal fibroblasts. Inferior turbinate and nasal polyp fibroblasts were stimulated with Alternaria or Aspergillus, respectively, for 24 hours and ECM messenger RNA (mRNA) and protein expressions were measured. Eosinophils isolated from healthy volunteers were stimulated with Alternaria or Aspergillus for 4 hours then superoxide, eosinophil peroxidase, and transforming growth factor β1 were measured. Then activated eosinophils were cocultured with nasal fibroblasts for 24 hours, and ECM mRNA expressions were measured. Alternaria strongly enhanced ECM mRNA expression and protein production from nasal fibroblasts. Alternaria also induced the production of superoxide, eosinophil peroxidase, and transforming growth factor β1 from eosinophils, and activated eosinophils enhanced ECM mRNA expression when they were cocultured without the Transwell insert system. Eosinophils activated with Alternaria enhanced ECM mRNA expression from nasal polyp fibroblasts. Alternaria plays an important role in tissue fibrosis in the pathogenesis of nasal polyps by directly or indirectly influencing the production of ECM from nasal fibroblasts. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  12. Production-on-the-Go Practice: Storyboarding as a Retrospective and Redundant School Literacy Activity

    Science.gov (United States)

    Tan, Lynde

    2013-01-01

    Storyboarding is one common strategy used in teaching young people digital media. This paper argues that in adolescents' literacy practices, they engage in production on the go. The metaphor is described in this paper to put forward the argument that storyboarding can be a retrospective and redundant literacy activity in adolescents' school…

  13. 78 FR 72861 - Foreign-Trade Zone (FTZ) 20-Suffolk, Virginia, Notification of Proposed Production Activity...

    Science.gov (United States)

    2013-12-04

    ... and boxes; plastic fuel tanks; metal filters; pipes (parts of generators); radiators and caps; tow bar... Authority, grantee of FTZ 20, submitted a notification of proposed production activity to the FTZ Board on... to the requirements of the regulations of the FTZ Board (15 CFR 400.22) was received on November 21...

  14. Pigment and amylase production in Penicillium sp NIOM-02 and its radical scavenging activity

    Digital Repository Service at National Institute of Oceanography (India)

    Dhale, M.A.; VijayRaj, A.S.

    )) in culture medium No. 5 and the zymogram analysis revealed its molecular mass (53 kDa). The taka-amylase like character of amylase was determined by acarbose incorporated studies in the culture media. Production of pigment and radical scavenging activity...

  15. Microbial electrolysis contribution to anaerobic digestion of waste activated sludge, leading to accelerated methane production

    DEFF Research Database (Denmark)

    Liu, Wenzong; Cai, Weiwei; Guo, Zechong

    2016-01-01

    Methane production rate (MPR) in waste activated sludge (WAS) digestion processes is typically limitedby the initial steps of complex organic matter degradation, leading to a limited MPR due to sludgefermentation speed of solid particles. In this study, a novel microbial electrolysis AD reactor (ME...

  16. Effects of sleep deprivation on event-related fields and alpha activity during rhythmic force production

    NARCIS (Netherlands)

    Boonstra, T.W.; Daffertshofer, A.; Beek, P.J.

    2005-01-01

    The influence of sleep deprivation (SD) on event-related fields and the distribution of power over the scalp of MEG imaged brain activity was studied during acoustically paced rhythmic force production. At the behavioral level, SD resulted in a reduction of the lag (negative asynchrony) between

  17. 78 FR 28577 - Notification of Proposed Production Activity: Whirlpool Corporation Subzone 8I; (Washing Machines...

    Science.gov (United States)

    2013-05-15

    ... machine parts to the list of approved finished products and would also add imported components to the...; refrigeration parts; dishwashing machine parts; drying machine parts; water inlet valves; AC/DC fan motors; AC... Activity: Whirlpool Corporation Subzone 8I; (Washing Machines): Clyde and Green Springs, Ohio Whirlpool...

  18. Learner uptake and acquisition in three grammar-oriented production activities

    NARCIS (Netherlands)

    Reinders, Hayo

    This study investigates the effects of three types of production activities on uptake (operationalized as correct suppliance of the target structure during the treatment) and acquisition of negative adverbs in English. It also investigates the relationship between uptake and acquisition. The three

  19. The effects of an active live yeast product on the growth performance ...

    African Journals Online (AJOL)

    A study was conducted to evaluate the effects of a rumen-specific, active live yeast (Saccharomyces cerevisiae; SC CNCM I-1077), alone or in combination with an ionophore (lasalocid-Na) in standard feedlot diets, on production performance and carcass quality of lambs. Sixty South African (S.A.) Mutton Merino lambs, ...

  20. Marketing activities to support ‘Moderately Novel’ product innovation: Insights from the chemical industry

    NARCIS (Netherlands)

    Smits, A.A.J.; Vissers, G.A.N.; Dankbaar, B.

    2015-01-01

    Scholars often follow a contingency approach to study which marketing activities are suitable for a particular type of product innovation project, thereby making a distinction between incremental and radical innovation only. ‘Moderately novel’ projects, which have intermediate levels of newness,

  1. Overview of approaches to sustain forest productivity during forest road development and timber harvesting activities

    Science.gov (United States)

    Charles R. Blinn; Rick Dahlamn; James A. Mattson; Michael A. Thompson

    1999-01-01

    Various approaches are available to minimize impacts on forest productivity during forest road building and timber harvesting activities. These approaches include a variety of practices and technologies. They include practices such as reducing road and trail development, using designated trails, and leaving slash at the stump on nutrient deficient sites. Technology...

  2. 77 FR 50462 - Notification of Proposed Production Activity; Winnebago Industries, Inc., Subzone 107A...

    Science.gov (United States)

    2012-08-21

    ... July 24, 2012. The subzone currently has authority to produce and warehouse recreational vehicles under.... Production under FTZ procedures for this activity could exempt Winnebago from customs duty payments on the... choose the duty rate during customs entry procedures that applies to motor homes (duty rate 2.5%) for the...

  3. The effects of an active live yeast product on the growth performance ...

    African Journals Online (AJOL)

    uvp

    Abstract. A study was conducted to evaluate the effects of a rumen-specific, active live yeast (Saccharomyces cerevisiae; SC CNCM I-1077), alone or in combination with an ionophore (lasalocid-Na) in standard feedlot diets, on production performance and carcass quality of lambs. Sixty South African (S.A.) Mutton Merino.

  4. Interleukin-2 stimulates osteoclastic activity: Increased acid production and radioactive calcium release

    International Nuclear Information System (INIS)

    Ries, W.L.; Seeds, M.C.; Key, L.L.

    1989-01-01

    Recombinant human interleukin-2 (IL-2) was studied to determine effects on acid production by individual osteoclasts in situ on mouse calvarial bones. This analysis was performed using a microspectrofluorimetric technique to quantify acid production in individual cells. Radioactive calcium release was determined using calvarial bones in a standard tissue culture system. This allowed us to correlate changes in acid production with a measure of bone resorption. IL-2 stimulated acid production and bone resorbing activity. Both effects were inhibited by calcitonin. No stimulation of bone resorption occurred when IL-2-containing test media was incubated with a specific anti-IL-2 antibody and ultrafiltered. Our data demonstrated a correlation between acid production and bone resorbing activity in mouse calvaria exposed to parathyroid hormone (PTH). The data obtained from cultured mouse calvaria exposed to IL-2 demonstrated similar stimulatory effects to those seen during PTH exposure. These data suggest that calvaria exposed to IL-2 in vitro have increased osteoclastic acid production corresponding with increased bone resorption. (author)

  5. Insects: an underrepresented resource for the discovery of biologically active natural products

    Directory of Open Access Journals (Sweden)

    Lauren Seabrooks

    2017-07-01

    Full Text Available Nature has been the source of life-changing and -saving medications for centuries. Aspirin, penicillin and morphine are prime examples of Nature׳s gifts to medicine. These discoveries catalyzed the field of natural product drug discovery which has mostly focused on plants. However, insects have more than twice the number of species and entomotherapy has been in practice for as long as and often in conjunction with medicinal plants and is an important alternative to modern medicine in many parts of the world. Herein, an overview of current traditional medicinal applications of insects and characterization of isolated biologically active molecules starting from approximately 2010 is presented. Insect natural products reviewed were isolated from ants, bees, wasps, beetles, cockroaches, termites, flies, true bugs, moths and more. Biological activities of these natural products from insects include antimicrobial, antifungal, antiviral, anticancer, antioxidant, anti-inflammatory and immunomodulatory effects.

  6. Study on Effects of Electron Donors on Phosphine Production from Anaerobic Activated Sludge

    Directory of Open Access Journals (Sweden)

    Jianping Cao

    2017-07-01

    Full Text Available The effects of different types and concentrations of electron donors (glucose, starch, methanol and sodium acetate on the formation of phosphine from anaerobic activated sludge that has been domesticated for a prolonged period were studied in small batch experiments. The results show that types and concentrations of electron donor have significant effects on the production of phosphine from anaerobic activated sludge. Among them, glucose was the most favourable electron donor, whereas sodium acetate was the least favourable electron donor for the removal of phosphorus and the production of phosphine. Higher concentrations of electron donors were more favourable for the reduction of phosphate into phosphine, and supplying more than nine times the amount of electron donor as theoretically required for the reduction of phosphate into phosphine was favourable for the production of phosphine.

  7. 78 FR 30270 - Foreign-Trade Zone (FTZ) 61-San Juan, Puerto Rico, Notification of Proposed Production Activity...

    Science.gov (United States)

    2013-05-22

    .... The facility is used for the production of various prescription and over-the-counter pharmaceutical... to various prescription and over-the-counter pharmaceutical products, including: Anti-cancer; anti..., Puerto Rico, Notification of Proposed Production Activity, Janssen Ortho LLC (Pharmaceutical Products...

  8. CALCUL DU DEPHASAGE A LA REFLEXION ET DES INDICES OPTIQUES DE L’ALLIAGE AMORPHE PD30Y70 A PARTIR DE LA MESURE DE SA REFLEXION

    Directory of Open Access Journals (Sweden)

    H BELBAH

    2002-06-01

    Full Text Available Les couches minces de l’alliage amorphe de composition Pd30Y70 sont déposées par pulvérisation cathodique sur des substrats en silice, sous un vide de 10-7 Torr. Les couches obtenues sont opaques et par conséquent leur transmission est nulle. Le spectre de réflexion de Pd30Y70  est mesuré dans le domaine d’énergie entre 0,5 et 6,2 eV. Cette mesure sert au calcul du déphasage à la réflexion de l’alliage à partir de l’intégrale de Kramers-Kronig. Les valeurs mesurées de la réflexion et les valeurs calculées du déphasage à la réflexion permettent de remonter aux constantes optiques (indices de réfraction et d’extinction de l’alliage et à sa structure électronique à partir des spectres d’absorption optique calculés. Le spectre d’absorption optique de Pd30Y70 amorphe est dominé par deux structures dont l’une est due aux états 4d de Pd centrée autour de 4 eV et l’autre aux états 4d de Y aux basses énergies.

  9. Aspects et mesure de la qualité de vie : évolution et renouvellement des tableaux de bord métropolitains

    Directory of Open Access Journals (Sweden)

    Pierre J. Hamel

    2008-02-01

    Full Text Available La mesure de la qualité de vie à l’intérieur des espaces urbains préoccupe les administrations publiques depuis nombre d’années. Cet article passe en revue les modèles de mesure de la qualité de vie développés par les métropoles canadiennes. Il s’interroge sur l’évolution de ces modèles de mesure et sur leur capacité à rendre compte des différentes problématiques désormais associées à la notion de qualité de vie comme le développement social, l’environnement, la société du risque, les ambiances urbaines ou la compétitivité urbaine.For a number of years now, government bodies at all levels have been concerned with measuring quality of life within urban areas. This paper reviews the models used by Canada’s metropolises to measure quality of life. It examines how the models have evolved and their capacity to consider various issues which have become associated with the notion of quality of life, such as social development, environment, risk society, urban surroundings, or urban competitiveness.

  10. Electronic temperature measurement on the deca II plasma using the Bremsstrahlung; Mesure de la temperature electronique du plasma de deca II par etude du rayonnement de freinage

    Energy Technology Data Exchange (ETDEWEB)

    Dumas, A. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1967-06-01

    The electronic temperature of the DECA II machine's plasma is determined by studying the Bremsstrahlung. Two types of detectors are used for this measurement, a set scintillator-photo-multiplicator and a photoelectric effect detector with a massive silver target. The method used is the classical 'absorbent method', The absorbents used are thin formvar foils whose thickness is between 600 and 12 500 angstrom. The measurements done in two different working conditions of the DECA II machine have given: Te {approx_equal} 200 eV in the first case and Te {approx_equal} 70 eV in the second case. (author) [French] Nous avons determine la temperature electronique du plasma de la machine DECA II par l'etude du rayonnement de freinage. Pour cette mesure nous avons utilise deux types de detecteurs: des ensembles scintillateur-photomultiplicateur et un detecteur a effet photoelectrique a cible massive en argent. La methode utilisee pour cette mesure est la classique methode des absorbants. Nous avons utilise des feuilles de format tres mince (de 600 a 12 500 angstrom) comme absorbant. Les mesures faites dans deux regimes de travail differents de la machine DECA II nous ont conduit a: Te {approx_equal} 200 eV dans un cas et Te {approx_equal} eV dans l'autre cas. (auteur)

  11. Mesure des stades de developpement du sapin baumier (Abies balsamea [L.] Mill.) par teledetection des maxima locaux sur images a tres haute resolution

    Science.gov (United States)

    Demers, Alain

    L'objectif principal de cette these est d'identifier les parametres cles pour lier le developpement morphologique de la cime du sapin baumier (Abies balsamea [L.] Mill.) aux patrons de reflectance qu'elle genere sur une image aerienne a haute resolution. La quantite et la distribution spatiale des aiguilles dans le sapin dependent de la structure des branches. Un mecanisme de ramification particulier (la reiteration) ressort comme le parametre cle pour lier l'augmentation de la biomasse foliaire et la forme de la branche. Les reiterats forment des agglomerats de feuillage qui engendrent des inegalites dans les patrons de reflectance de la cime. La reflectance est plus elevee ou il y a une forte concentration de reiterats (maximum local). On demontre que le developpement du sapin baumier se mesure au moyen de l'analyse des maxima locaux de la cime sur une image. La biomasse de l'arbre se mesure par la teledetection et l'analyse des patrons de reflectance de la cime, c'est-a-dire la mesure du niveau de reiteration par le decompte des maxima locaux de la cime. Cette etude demontre qu'il est possible de proceder a l'inventaire du volume de bois d'un peuplement par la teledetection de l'architecture des arbres.

  12. Mesure asymétrie avant-arriere des quarks lourds a LEP1 avec le détecteur OPAL

    CERN Document Server

    Lafoux, H

    A partir de l'ensemble des données accumulées par OPAL au cours de la première phase de fonctionnement du LEP, nous avons mesuré l'asymétrie avant-arrière des quarks b et c au voisinage du pic du Zo. Utilisant une méthode traditionnelle, basée sur la détection des leptons produits dans les désintégrations semi-leptoniques des hadrons lourds, nous avons cherché à optimiser chaque étape de la mesure, en mettant en œuvre les algorithmes les plus appropriés. Le recours aux réseaux de neurones artificiels s'est en particulier avéré d'une grande utilité lorsque le problème à résoudre impliquait la prise en compte simultanée de multiples sources d'informations, d'origine et de nature très variées. Nos résultats sont en bon accord avec ceux des autres mesures effectuées à LEP et compatibles avec les prédictions du Modèle Standard pour un quark top de 174 ± 31 GeV/c2 et un boson de Higgs de masse comprise entre 60 et 1000 GeV/c2

  13. Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells.

    Science.gov (United States)

    Carvalho, Larissa A C; Lopes, João P P B; Kaihami, Gilberto H; Silva, Railmara P; Bruni-Cardoso, Alexandre; Baldini, Regina L; Meotti, Flavia C

    2018-06-01

    Uric acid is the end product of purine metabolism in humans and is an alternative physiological substrate for myeloperoxidase. Oxidation of uric acid by this enzyme generates uric acid free radical and urate hydroperoxide, a strong oxidant and potentially bactericide agent. In this study, we investigated whether the oxidation of uric acid and production of urate hydroperoxide would affect the killing activity of HL-60 cells differentiated into neutrophil-like cells (dHL-60) against a highly virulent strain (PA14) of the opportunistic pathogen Pseudomonas aeruginosa. While bacterial cell counts decrease due to dHL-60 killing, incubation with uric acid inhibits this activity, also decreasing the release of the inflammatory cytokines interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF- α). In a myeloperoxidase/Cl - /H 2 O 2 cell-free system, uric acid inhibited the production of HOCl and bacterial killing. Fluorescence microscopy showed that uric acid also decreased the levels of HOCl produced by dHL-60 cells, while significantly increased superoxide production. Uric acid did not alter the overall oxidative status of dHL-60 cells as measured by the ratio of reduced (GSH) and oxidized (GSSG) glutathione. Our data show that uric acid impairs the killing activity of dHL-60 cells likely by competing with chloride by myeloperoxidase catalysis, decreasing HOCl production. Despite diminishing HOCl, uric acid probably stimulates the formation of other oxidants, maintaining the overall oxidative status of the cells. Altogether, our results demonstrated that HOCl is, indeed, the main relevant oxidant against bacteria and deviation of myeloperoxidase activity to produce other oxidants hampers dHL-60 killing activity. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  14. The Influence of Consumer Goals and Marketing Activities on Product Bundling

    Science.gov (United States)

    Haijun, Wang

    Upon entering a store, consumers are faced with the questions of whether to buy, what to buy, and how much to buy. Consumers include products from different categories in their decision process. Product categories can be related in different ways. Product bundling is a process that involves the choice of at least two non-substitutable items. In this research, the consumers' explicit product bundling activity at the point of sale is focused. We focuses on the retailers' perspective and therefore leaves out consumers' brand choice decisions, concentrating on purchase incidence and quantity. At the base of the current model of the exist researches, we integrate behavioural choice analysis and predictive choice modelling through the underlying behavioural models, called random utility maximization (RUM) models. The methodological contribution of this research lies therein to combine a nested logit choice model with a latent variable factor model. We point out several limitations for both theory and practice at the end.

  15. Biological activities of Agave by-products and their possible applications in food and pharmaceuticals.

    Science.gov (United States)

    López-Romero, Julio Cesar; Ayala-Zavala, Jesús Fernando; González-Aguilar, Gustavo Adolfo; Peña-Ramos, Etna Aida; González-Ríos, Humberto

    2017-10-11

    Agave leaves are considered a by-product of alcoholic beverage production (tequila, mezcal and bacanora) because they are discarded during the production process, despite accounting for approximately 50% of the total plant weight. These by-products constitute a potential source of Agave extracts rich in bioactive compounds, such as saponins, phenolic compounds and terpenes, and possess different biological effects, as demonstrated by in vitro and in vivo tests (e.g. antimicrobial, antifungal, antioxidant, anti-inflammatory, antihypertensive, immunomodulatory, antiparasitic and anticancer activity). Despite their positive results in biological assays, Agave extracts have not been widely evaluated in food systems and pharmaceutical areas, and these fields represent a potential route to improve the usage of Agave plants as food additives and agents for treating medical diseases. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  16. Alternative radiochemical heavy ion activation methods for the production and separation of thallium radionuclides

    International Nuclear Information System (INIS)

    Nayak, Dalia; Lahiri, Susanta.; Ramaswami, A.

    2002-01-01

    Heavy ion activation of natural gold foil with a 7 Li beam results in the formation of carrier-free 199-201 Pb radionuclides along with their corresponding decay products, 199-201 Tl, in the matrix. At 49 MeV projectile energy, the production of 199 Tl through its precursor 199 Pb is maximal, while that of other thallium radionuclides is minimal. Another way for the direct production of carrier-free thallium radionuclides is to irradiate natural platinum foil with a 7 Li beam; on this case, production of 199 Tl is maximal at 43 MeV projectile energy. The carrier-free thallium radionuclides have been separated from the bulk target matrix gold and platinum by liquid-liquid extraction using trioctylamine as a liquid anion exchanger

  17. Cash transfer programme, productive activities and labour supply: Evidence from randomized experiment in Kenya

    Science.gov (United States)

    Asfaw, Solomon; Davis, Benjamin; Dewbre, Josh; Handa, Sudhanshu; Winters, Paul

    2015-01-01

    This paper reports analysis of the impact of Kenya’s Cash Transfer for Orphans and Vulnerable Children Programme on the household decisions on productive activities using data from a randomized experimental design. Results show that the programme had a positive and significant impact on food consumption coming from home production, accumulation of productive assets, especially on the ownership of small livestock and on formation of nonfarm enterprise, especially for females. The programme has provided more flexibility to families in terms of labour allocation decisions, particularly for those who are geographically isolated. The programme was also found to have reduced child labour, an important objective of the programme. However we find very little impact of the programme on direct indicators of crop production. PMID:25663712

  18. Efficient production of infectious viruses requires enzymatic activity of Epstein-Barr virus protein kinase.

    Science.gov (United States)

    Murata, Takayuki; Isomura, Hiroki; Yamashita, Yoriko; Toyama, Shigenori; Sato, Yoshitaka; Nakayama, Sanae; Kudoh, Ayumi; Iwahori, Satoko; Kanda, Teru; Tsurumi, Tatsuya

    2009-06-20

    The Epstein-Barr virus (EBV) BGLF4 gene product is the only protein kinase encoded by the virus genome. In order to elucidate its physiological roles in viral productive replication, we here established a BGLF4-knockout mutant and a revertant virus. While the levels of viral DNA replication of the deficient mutant were equivalent to those of the wild-type and the revertant, virus production was significantly impaired. Expression of the BGLF4 protein in trans fully complemented the low yield of the mutant virus, while expression of a kinase-dead (K102I) form of the protein failed to restore the virus titer. These results demonstrate that BGLF4 plays a significant role in production of infectious viruses and that the kinase activity is crucial.

  19. Sympathomimetic Activity of a Hoodia gordonii Product: A Possible Mechanism of Cardiovascular Side Effects

    Directory of Open Access Journals (Sweden)

    Orsolya Roza

    2013-01-01

    Full Text Available Hoodia gordonii, a popular appetite suppressant, is widely used as an ingredient in many food supplements despite the fact that supporting scientific evidence is scarce. Recently alarming side effects of H. gordonii products (increased blood pressure and elevated pulse rate have been reported. The aim of our study was to elucidate the underlying mechanism of these symptoms. A H. gordonii-containing product was tested for sympathomimetic activity. Isolated organ experiments on rat uterine rings revealed smooth muscle relaxant effect with a substantial component mediated through β-adrenergic receptors. Chromatographic comparison of the analyzed product and authentic plant material confirmed that the herbal product contained Hoodia spp. extract, and its cardiovascular effects may be linked to the compounds of the plant.

  20. Common commercial and consumer products contain activators of the aryl hydrocarbon (dioxin receptor.

    Directory of Open Access Journals (Sweden)

    Bin Zhao

    Full Text Available Activation of the Ah receptor (AhR by halogenated aromatic hydrocarbons (HAHs, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin, can produce a wide variety of toxic and biological effects. While recent studies have shown that the AhR can bind and be activated by structurally diverse chemicals, how widespread of these AhR agonists are in environmental, biological and synthetic materials remains to be determined. Using AhR-based assays, we demonstrate the presence of potent AhR agonists in a variety of common commercial and consumer items. Solvent extracts of paper, rubber and plastic products contain chemicals that can bind to and stimulate AhR DNA binding and/or AhR-dependent gene expression in hepatic cytosol, cultured cell lines, human epidermis and zebrafish embryos. In contrast to TCDD and other persistent dioxin-like HAHs, activation of AhR-dependent gene expression by these extracts was transient, suggesting that the agonists are metabolically labile. Solvent extracts of rubber products produce AhR-dependent developmental toxicity in zebrafish in vivo, and inhibition of expression of the metabolic enzyme CYP1A, significantly increased their toxic potency. Although the identity of the responsible AhR-active chemicals and their toxicological impact remain to be determined, our data demonstrate that AhR active chemicals are widely distributed in everyday products.

  1. Spatiotemporal dynamics of word retrieval in speech production revealed by cortical high-frequency band activity.

    Science.gov (United States)

    Riès, Stephanie K; Dhillon, Rummit K; Clarke, Alex; King-Stephens, David; Laxer, Kenneth D; Weber, Peter B; Kuperman, Rachel A; Auguste, Kurtis I; Brunner, Peter; Schalk, Gerwin; Lin, Jack J; Parvizi, Josef; Crone, Nathan E; Dronkers, Nina F; Knight, Robert T

    2017-06-06

    Word retrieval is core to language production and relies on complementary processes: the rapid activation of lexical and conceptual representations and word selection, which chooses the correct word among semantically related competitors. Lexical and conceptual activation is measured by semantic priming. In contrast, word selection is indexed by semantic interference and is hampered in semantically homogeneous (HOM) contexts. We examined the spatiotemporal dynamics of these complementary processes in a picture naming task with blocks of semantically heterogeneous (HET) or HOM stimuli. We used electrocorticography data obtained from frontal and temporal cortices, permitting detailed spatiotemporal analysis of word retrieval processes. A semantic interference effect was observed with naming latencies longer in HOM versus HET blocks. Cortical response strength as indexed by high-frequency band (HFB) activity (70-150 Hz) amplitude revealed effects linked to lexical-semantic activation and word selection observed in widespread regions of the cortical mantle. Depending on the subsecond timing and cortical region, HFB indexed semantic interference (i.e., more activity in HOM than HET blocks) or semantic priming effects (i.e., more activity in HET than HOM blocks). These effects overlapped in time and space in the left posterior inferior temporal gyrus and the left prefrontal cortex. The data do not support a modular view of word retrieval in speech production but rather support substantial overlap of lexical-semantic activation and word selection mechanisms in the brain.

  2. Blockade of leukotriene production by a single oral dose of MK-0591 in active ulcerative colitis

    DEFF Research Database (Denmark)

    Hillingsø, Jens; Kjeldsen, J; Laursen, L S

    1995-01-01

    -ethyl)thio)-5(quinolin+ ++-2ylmethyl-oxy)-1H-indol-2yl)-2,2-dimethyl-propanoate) exerts its effect by binding to the 5-lipoxygenase activating protein, thereby inhibiting the translocation and activation of 5-lipoxygenase. METHODS: Concentrations of leukotriene B4 (LTB4) and prostaglandin E2 (PGE2) in rectal...... that a single oral 250 mg dose of MK-0591 results in nearly complete blockade of systemic leukotriene production and LTB4 formation in the target tissue of inflammation (the rectum). Controlled multiple-dose trials to assess the clinical efficacy of this novel 5-lipoxygenase-activating protein inhibitor seem......BACKGROUND: 5-Lipoxygenase products of arachidonic acid metabolism are thought to play a central role in the secondary amplification of the inflammatory response in a number of human inflammatory diseases, such as ulcerative colitis. MK-0591 (3-(1((4-chlorophenyl)methyl)-3((1,1-dimethyl...

  3. Preliminary Study on Kano Model in the Conceptual Design Activities for Product Lifecycle Improvement

    Science.gov (United States)

    Fahrul Hassan, Mohd; Rahman, M. R. A.; Arifin, A. M. T.; Ismail, A. E.; Rasidi Ibrahim, M.; Zulafif Rahim, M.; Fauzi Ahmad, Md

    2017-08-01

    Product manufactured with short life cycle had only one major issue, it can lead to increasing volume of waste. Day by day, this untreated waste had consumed many landfill spaces, waiting for any possible alternatives. Lack of product recovery knowledge and recyclability features imprinted into product design are one of the main reason behind all this. Sustainable awareness aspect should not just be implied into people’s mind, but also onto product design. This paper presents a preliminary study on Kano model method in the conceptual design activities to improve product lifecycle. Kano model is a survey-type method, used to analyze and distinguished product qualities or features, also how the customers may have perceived them. Three important attributes of Kano model are performance, attractive and must-be. The proposed approach enables better understanding of customer requirements while providing a way for Kano model to be integrated into engineering design to improve product’s end-of-life. Further works will be continued to provide a better lifecycle option (increase percentage of reuse, remanufacture or recycle, whereby decrease percentage of waste) of a product using Kano model approach.

  4. Total Content of Phenolics and Antioxidant Activity in Crispbreads with Plant By-product addition

    Directory of Open Access Journals (Sweden)

    Konrade Daiga

    2017-11-01

    Full Text Available Vegetable processing in food industry results in significant amount of by-products – peel, mark, bark, seeds still rich in bioactive compounds. Apple, carrot and pumpkin peel and mark may be used for production of crispbreads as functional ingredients. The objective of this study is to investigate the stability of total phenolic content (TPC and antioxidant activity after high temperature and short time (HTST extrusion cooking of a wheat and rice-based crispbreads with addition of apple, carrot and pumpkin by-products obtained after juice extraxtion and dried. Raw materials for crispbread production were wheat flour, rice flour, wheat bran (72%, 24% and 4% respectively with addition of microwave–vacuum dried by-product powder in different amount (5%, 10%, 15%, 20%. Extrusion process was performed by using a laboratory singlescrew extruder GÖTTFERT 1 screw Extrusiometer L series (Germany. Total phenolic content (TPC was determined using the Folin Ciocalteu method. Antioxidant activity was evaluated by free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH antioxidant scavenging activity using a modified colorimetric method. Comparing different raw formulations, it was observed that the TPC of the apple by-product flour was significantly higher (p < 0.05 than in carrot and pumpkin flour. TPC in cereal-based crispbread was 36.06±1.15 before extrusion and 13.90±1.01 mg GAEg-1 DW (milligram Gallic acid equivalent per 100 g of dry weight (mg GAE 100 g−1 DW after extrusion. Addition of apple BPF increased TPC in crispbreads to 106.25±2.08, carrot BPF 84.73±3.45 and pumpkin BPF to 108.82±1.04 mg GAEg−1 DW. Antioxidant activity of control sample was 1.07±0.01mg TE (Trolox equivalents g−1 DW but in samples with addition of 20% apple by-products, it reached 3.77±0.02 TE g−1 DW for samples wih 20% carrot by-products reached 2.52±0.03TE g−1 DW and for samples wih 20% pumpkin by-products reached 3.77±0.02 TE g−1 DW.

  5. Isolation of Lactic Acid Bacteria with High Biological Activity from Local Fermented Dairy Products

    Directory of Open Access Journals (Sweden)

    B. Munkhtsetseg

    2009-12-01

    Full Text Available The thirty-two strains of lactic acid bacteria were isolated from the Mongolian traditional fermented dairy products, among them 25 strains show antimicrobial activity against test microorganisms including Escherichia coli , Staphylococcus aureus , Enterococcus faecalis , Pseudom о nas aeruginosa . Protease sensitivity assay demonstrated that the antimicrobial substances produced by isolates А 23, Т 2 are bacteriocins as their antibacterial activities were eliminated completely after treatment with protease. Identi fi cation of bacteria is being carried out. Among the isolates 22 strains show protease enzyme producing activity. The selected strains isolated from mare’s fermented milk (airag or kumis and yoghurt (tarag show the speci fi c protease activity from 7.9 μ g/ml to 11.9 μ g/ml. The strain T2, isolated from yoghurt exhibited the highest proteolytic activity.

  6. Calculating Program for Decommissioning Work Productivity based on Decommissioning Activity Experience Data

    International Nuclear Information System (INIS)

    Song, Chan-Ho; Park, Seung-Kook; Park, Hee-Seong; Moon, Jei-kwon

    2014-01-01

    KAERI is performing research to calculate a coefficient for decommissioning work unit productivity to calculate the estimated time decommissioning work and estimated cost based on decommissioning activity experience data for KRR-2. KAERI used to calculate the decommissioning cost and manage decommissioning activity experience data through systems such as the decommissioning information management system (DECOMMIS), Decommissioning Facility Characterization DB System (DEFACS), decommissioning work-unit productivity calculation system (DEWOCS). In particular, KAERI used to based data for calculating the decommissioning cost with the form of a code work breakdown structure (WBS) based on decommissioning activity experience data for KRR-2.. Defined WBS code used to each system for calculate decommissioning cost. In this paper, we developed a program that can calculate the decommissioning cost using the decommissioning experience of KRR-2, UCP, and other countries through the mapping of a similar target facility between NPP and KRR-2. This paper is organized as follows. Chapter 2 discusses the decommissioning work productivity calculation method, and the mapping method of the decommissioning target facility will be described in the calculating program for decommissioning work productivity. At KAERI, research on various decommissioning methodologies of domestic NPPs will be conducted in the near future. In particular, It is difficult to determine the cost of decommissioning because such as NPP facility have the number of variables, such as the material of the target facility decommissioning, size, radiographic conditions exist

  7. Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria

    Science.gov (United States)

    Chiou, Shu-Yuan; Ha, Choi-Lan; Wu, Pei-Shan; Yeh, Chiu-Ling; Su, Ying-Shan; Li, Man-Po; Wu, Ming-Jiuan

    2015-01-01

    Camellia tenuifloria is an indigenous Camellia species used for the production of camellia oil in Taiwan. This study investigated for the first time the potential antioxidant, anti-tyrosinase and anti-inflammatory activities of oil production byproducts, specifically those of the fruit shell, seed shell, and seed pomace from C. tenuifloria. It was found that the crude ethanol extract of the seed shell had the strongest DPPH scavenging and mushroom tyrosinase inhibitory activities, followed by the fruit shell, while seed pomace was the weakest. The IC50 values of crude extracts and fractions on monophenolase were smaller than diphenolase. The phenolic-rich methanol fraction of seed shell (SM) reduced nitric oxide (NO) production, and inducible nitric oxide synthase (iNOS) expression in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. It also repressed the expression of IL-1β, and secretion of prostaglandin E2 (PGE2) and IL-6 in response to LPS. SM strongly stimulated heme oxygenase 1 (HO-1) expression and addition of zinc protoporphyrin (ZnPP), a HO-1 competitive inhibitor, reversed the inhibition of NO production, indicating the involvement of HO-1 in its anti-inflammatory activity. The effects observed in this study provide evidence for the reuse of residues from C. tenuifloria in the food additive, medicine and cosmetic industries. PMID:26690417

  8. Antioxidant, Anti-Tyrosinase and Anti-Inflammatory Activities of Oil Production Residues from Camellia tenuifloria

    Directory of Open Access Journals (Sweden)

    Shu-Yuan Chiou

    2015-12-01

    Full Text Available Camellia tenuifloria is an indigenous Camellia species used for the production of camellia oil in Taiwan. This study investigated for the first time the potential antioxidant, anti-tyrosinase and anti-inflammatory activities of oil production byproducts, specifically those of the fruit shell, seed shell, and seed pomace from C. tenuifloria. It was found that the crude ethanol extract of the seed shell had the strongest DPPH scavenging and mushroom tyrosinase inhibitory activities, followed by the fruit shell, while seed pomace was the weakest. The IC50 values of crude extracts and fractions on monophenolase were smaller than diphenolase. The phenolic-rich methanol fraction of seed shell (SM reduced nitric oxide (NO production, and inducible nitric oxide synthase (iNOS expression in lipopolysaccharide (LPS-stimulated RAW 264.7 cells. It also repressed the expression of IL-1β, and secretion of prostaglandin E2 (PGE2 and IL-6 in response to LPS. SM strongly stimulated heme oxygenase 1 (HO-1 expression and addition of zinc protoporphyrin (ZnPP, a HO-1 competitive inhibitor, reversed the inhibition of NO production, indicating the involvement of HO-1 in its anti-inflammatory activity. The effects observed in this study provide evidence for the reuse of residues from C. tenuifloria in the food additive, medicine and cosmetic industries.

  9. Penrose pair production as a power source of quasars and active galactic nuclei. [black hole mechanisms

    Science.gov (United States)

    Kafatos, M.; Leiter, D.

    1979-01-01

    Penrose pair production in massive canonical Kerr black holes (those with a/M equal to 0.998) is proposed as a way to explain the nature of the vast fluctuating energy production associated with active galactic nuclei and quasars. It is assumed that a Kerr black hole with a mass of the order of 100 million solar masses lies at the center of an active nucleus and that an accretion disk is formed. Penrose pair production in the inner ergosphere of such a massive canonical Kerr black hole is analyzed. The results indicate that: (1) particle pairs are ejected within a 40 deg angle relative to the equator; (2) the particle energy is of the order of 1 GeV per pair; (3) the pressure of the electron-positron relativistic gas is proportional to the electron-positron number density; (4) pair production may occur in bursts; and (5) the overall lifetime of an active nucleus would depend on the time required to exhaust the disk of its matter content. A test of the theory is suggested which involves observation of the 0.5-MeV pair-annihilation gamma rays that would be generated by annihilating particle pairs.

  10. Calculating Program for Decommissioning Work Productivity based on Decommissioning Activity Experience Data

    Energy Technology Data Exchange (ETDEWEB)

    Song, Chan-Ho; Park, Seung-Kook; Park, Hee-Seong; Moon, Jei-kwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    KAERI is performing research to calculate a coefficient for decommissioning work unit productivity to calculate the estimated time decommissioning work and estimated cost based on decommissioning activity experience data for KRR-2. KAERI used to calculate the decommissioning cost and manage decommissioning activity experience data through systems such as the decommissioning information management system (DECOMMIS), Decommissioning Facility Characterization DB System (DEFACS), decommissioning work-unit productivity calculation system (DEWOCS). In particular, KAERI used to based data for calculating the decommissioning cost with the form of a code work breakdown structure (WBS) based on decommissioning activity experience data for KRR-2.. Defined WBS code used to each system for calculate decommissioning cost. In this paper, we developed a program that can calculate the decommissioning cost using the decommissioning experience of KRR-2, UCP, and other countries through the mapping of a similar target facility between NPP and KRR-2. This paper is organized as follows. Chapter 2 discusses the decommissioning work productivity calculation method, and the mapping method of the decommissioning target facility will be described in the calculating program for decommissioning work productivity. At KAERI, research on various decommissioning methodologies of domestic NPPs will be conducted in the near future. In particular, It is difficult to determine the cost of decommissioning because such as NPP facility have the number of variables, such as the material of the target facility decommissioning, size, radiographic conditions exist.

  11. Melanocortin peptides inhibit production of proinflammatory cytokines and nitric oxide by activated microglia.

    Science.gov (United States)

    Delgado, R; Carlin, A; Airaghi, L; Demitri, M T; Meda, L; Galimberti, D; Baron, P; Lipton, J M; Catania, A

    1998-06-01

    Inflammatory processes contribute to neurodegenerative disease, stroke, encephalitis, and other central nervous system (CNS) disorders. Activated microglia are a source of cytokines and other inflammatory agents within the CNS and it is therefore important to control glial function in order to preserve neural cells. Melanocortin peptides are pro-opiomelanocortin-derived amino acid sequences that include alpha-melanocyte-stimulating hormone (alpha-MSH) and adrenocorticotropic hormone (ACTH). These peptides have potent and broad anti-inflammatory effects. We tested effects of alpha-MSH (1-13), alpha-MSH (11-13), and ACTH (1-24) on production of tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), and nitric oxide (NO) in a cultured murine microglial cell line (N9) stimulated with lipopolysaccharide (LPS) plus interferon gamma (IFN-gamma). Melanocortin peptides inhibited production of these cytokines and NO in a concentration-related fashion, probably by increasing intracellular cAMP. When stimulated with LPS + IFN-gamma, microglia increased release of alpha-MSH. Production of TNF-alpha, IL-6, and NO was greater in activated microglia after innmunoneutralization of endogenous alpha-MSH. The results suggest that alpha-MSH is an autocrine factor in microglia. Because melanocortin peptides inhibit production of pro-inflammatory mediators by activated microglia they might be useful in treatment of inflammatory/degenerative brain disorders.

  12. Measurement of the total ionisation intensity near the ground and separation of the various components; Mesure de l'intensite totale d'ionisation au voisinage du sol et separation de ses differentes composantes

    Energy Technology Data Exchange (ETDEWEB)

    Grevet, Ph. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1965-06-01

    The aim of this work is to measure the total amount of ion-pairs produced in the air per unit time and unit volume. It is possible, furthermore, by using continuous recording to study the variations in the ionisation due to {alpha}, {beta} and {gamma} radiation at a height of one metre. The apparatus which has been developed consists of two chambers of 120 litres: one, hermetically sealed detects the {gamma} component, the other with a circulation of the ambient air detects the {alpha} and {gamma}; it is thus possible by difference to evaluate the {alpha} component. The chambers and the associated electronic equipment have been designed for continuous operation in the open air. Another chamber without walls can be used for measuring directly the total ionisation intensity and from this an approximate calculation may be made of the {beta} component. A series of recordings has been made near Saclay where the natural radio-activity level is moderate, and in regions of low and high activity (near the sea and in the CEA's mining divisions). It has thus been possible to show the variation in the {gamma} component as a function of the geographic position of the measurement (from 3.7 to 6.3 l/cm{sup 3}.s), the very large variations of the {alpha} component at a given place with changing meteorological conditions (from 1.5 to 45 l/cm{sup 3}.s at Saclay for example) an the far smaller variations in the {beta} component. (author) [French] Le but de ce travail est de mesurer la quantite totale de paires d'ions produite dans l'air par unite de temps et de volume. Des enregistrements continus permettent, de plus, d'etudier les variations a 1 m du sol de cette ionisation due aux rayonnements {alpha}, {beta} et {gamma}. L'appareillage mis au point est forme de deux chambres de 120 litres: l'une hermetiquement fermee detecte la composante {gamma}; l'autre avec circulation de l'air ambiant detecte {alpha} + {gamma} ce qui permet d

  13. Soluble microbial products (SMPs release in activated sludge systems: a review

    Directory of Open Access Journals (Sweden)

    Azami Hamed

    2012-12-01

    Full Text Available Abstract This review discusses the characterization, production and implications of soluble microbial products (SMPs in biological wastewater treatment. The precise definition of SMPs is open to talk about, but is currently regarded as “the pool of organic compounds that are released into solution from substrate metabolism and biomass decay”'. Some of the SMPs have been identified as humic acids, polysaccharides, proteins, amino acids, antibiotics, extracellular enzymes and structural components of cells and products of energy metabolism. They adversely affect the kinetic activity, flocculating and settling properties of sludge. This review outlines some important findings with regard to biodegradability and treatability of SMPs and also the effect of process parameters on their production. As SMPs are produced during biological treatment process, their trace amounts normally remain in the effluent that defines the highest COD removal efficiency. Their presence in effluent represents a high potential risk of toxic by-product formation during chlorine disinfection. Studies have indicated that among all wastewater post-treatment processes, the adsorption by granular activated carbon combined with biologically induced degradation is the most effective method for removal of SMPs. However, it may be concludes that the knowledge regarding SMPs is still under progress and more work is required to fully understand their contribution to the treatment process.

  14. CHEMICAL, PHYSICAL AND SENSORY ANALYSIS OF ACTIVITY DIFFERENT YEAST SPECIES ON IDENTICAL SUBSTRATE IN WINE PRODUCTION

    Directory of Open Access Journals (Sweden)

    Vladimír Vietoris

    2013-02-01

    Full Text Available Rizling vlašský is the second most important variety in Slovakia. The science of wine production includes a summary of knowledge and experience in the field of grape growing and wine making, or the production of different types of wines using specific methods of production. Wine quality is the result of the interaction between yeast, bacteria and microscopic funguses. In this research, we studied the effects of active dry wine yeasts on chemical, physical and sensory parameters in wine production. We have applied five kinds of yeasts (FERMIVIN, FERMIVIN PDV, FERMICRU AR2, FERMIFLOR and FERMICRU VB1. It can be concluded that the application of active dry wine yeasts is beneficial for the production of rizling vlašský. The best showing were yeasts FERMIFLOR and FERMIVIN PDM. In the last sample where they were left the original yeasts the varietal aroma was preserved. It can be noted that the wine was right technologically produced and all wines were harmonious with a pleasant fresh taste.

  15. POST-LAUNCHING MONITORING ACTIVITIES FOR NEW TRANSACTIONAL BANKING PRODUCTS ADDRESSED TO SMES (CONSIDERATIONS

    Directory of Open Access Journals (Sweden)

    Giuca Simona-Mihaela

    2014-07-01

    Full Text Available The current paper has the aim to provide guidelines for post-launching monitoring activities and steps related to new transactional banking products addressed to SMEs. While the pre-launching activities have the purpose of accurately defining the objectives, assumptions and estimations, the purpose of the post-launching plan is to identify: if the final objectives of a product launching have been met, on one hand, to analyze results in the sense of identifying an efficient action plan in order to overcome the lack of results (if case, but most important, to identify opportunities for optimizing the products and for communicating properly the value proposition. This paper also presents schemes for monitoring the results from a business case and for motivating the sales force, as an essential step in increasing the sales. Therefore, alternatives of incentive campaigns are presented, as sustainable campaigns with to purpose to achieve an expected success rate. As an additional support guideline for the sales force, some scenarios and post-sales actions are presented, together with an example of portfolio analysis considering potential per client. Considering the methods and details presented in the current paper, one can identify the importance and find out how to monitor the results after launching a new transactional product addressed to SMEs, can understand and design an incentive scheme and also define actions to be taken in order to increase revenues from a newly launched transactional product.

  16. Biosurfactants production potential of native strains of Bacillus cereus and their antimicrobial, cytotoxic and antioxidant activities.

    Science.gov (United States)

    Basit, Madiha; Rasool, Muhammad Hidayat; Naqvi, Syed Ali Raza; Waseem, Muhammad; Aslam, Bilal

    2018-01-01

    Present study was designed to evaluate the biosurfactant production potential by native strains of Bacillus cereus as well as determine their antimicrobial and antioxidant activities. The strains isolated from garden soil were characterized as B. cereus MMIC 1, MMIC 2 and MMIC 3. Biosurfactants were extracted as grey white precipitates. Optimum conditions for biosurfactant production were 37°C, the 7th day of incubation, 0.5% NaCl, pH 7.0. Moreover, corn steep liquor was the best carbon source. Biuret test, Thin Layer Chromatography (TLC), agar double diffusion and Fourier Transform Infrared Spectroscopy (FTIR) characterized the biosurfactants as cationic lipopeptides. Biosurfactants exhibited significant antibacterial and antifungal activity against S. aureus, E. coli, P. aeruginosa, K. pneumoniae, A. niger and C. albicans at 30 mg/ml. Moreover, they also possessed antiviral activity against NDV at 10 mg/ml. Cytotoxicity assay in BHK-21 cell lines revealed 63% cell survival at 10 mg/ml of biosurfactants and thus considered as safe. They also showed very good antioxidant activity by ferric-reducing activity and DPPH scavenging activity at 2 mg/ml. Consequently, the study offers an insight for the exploration of new bioactive molecules from the soil. It was concluded that lipopeptide biosurfactants produced from native strains of B. cereus may be recommended as safe antimicrobial, emulsifier and antioxidant agent.

  17. Cytochrome P450-inhibitory activity of parabens and phthalates used in consumer products.

    Science.gov (United States)

    Ozaki, Hitomi; Sugihara, Kazumi; Watanabe, Yoko; Ohta, Shigeru; Kitamura, Shigeyuki

    2016-01-01

    The in vitro cytochrome P450 (CYP)-inhibitory effects of 11 parabens and 7 phthalates used in consumer products, as well as their hydrolytic metabolites, were investigated, using rat liver microsomes as an enzyme source. The effects on individual CYP isozymes were evaluated by assaying inhibition of activities towards specific substrates, i.e., ethoxyresorufin O-dealkylase (EROD), methoxyresorufin O-dealkylase (MROD), pentoxyresorufin O-dealkylase (PROD), 7-benzyloxy-4-trifluoromethylcoumarin dealkylase (BFCD), 7-methoxy-4-trifluoromethylcoumarin dealkylase (MFCD) and 7-ethoxy-4-trifluoromethylcoumarin dealkylase (EFCD) activities. These activities were dose-dependently inhibited, most potently by medium-side-chain parabens (C6-9) and phthalates (C4-6), and less potently by shorter- and longer-side-chain esters. The hydrolytic product of parabens, 4-hydroxybenzoic acid, was not inhibitory, while those of phthalates, phthalic acid monoesters, showed lower inhibitory activity than the parent phthalates. Parabens showed relatively potent inhibition of MFCD activity, considered to be mainly due to CYP2C, and phthalates showed relatively potent inhibition of PROD activity, considered to be mainly due to CYP2B.

  18. Mesure De La Fraction D'evenements A Quatre Quarks Dans Les Desintegrations Multihadroniques Du Boson Z Au Lep

    CERN Document Server

    Lefebvre, E

    1999-01-01

    Cette thèse propose de tester la Chromodynamique Quantique (QCD) en effectuant une mesure précise d'une des trois constantes fondamentales du groupe de symétrie SU(3) utilisé pour décrire la physique des interactions fortes. Cette constante fondamentale, appelée TF, est reliée à certains états finaux spécifiques des désintégrations du Z0. Ces états apparaissent sous forme de perturbations du deuxième ordre en as et sont illustrés par des diagrammes de Feynman. À cet ordre, la chromodynamique prévoit deux types de diagrammes de Feynman distincts; le premier contient, un quark, un antiquark et deux gluons, et le second, deux quarks et deux antiquarks. La constante TF est directement proportionnelle à la fraction d'événements à deux quarks et deux antiquarks qui est l'objet de notr...

  19. La thèse de Feldstein-Horioka: Ue mesure de la mobilité internationale du capital

    Directory of Open Access Journals (Sweden)

    de Sousa Andrade Alberto Joao

    2007-01-01

    Full Text Available (portugalski Nous présentons la thèse de Feldstein-Horioka (F-H sur la mobilité du capital et les développements qu’elle a suscités. Il s’agit d’une thèse qui est très ouverte à la possibilité de réfutation et dont l’histoire illustre bien la pensée méthodologique nonnaïve de Karl Popper: les discussions sur sa réfutation, en parallèle avec les tentatives de consolidation ("d’immunisation", au sens de K. Popper, ont conduit à de nouvelles lectures sur la mobilité du capital. Ces efforts de consolidation (d’ "immunization" ont conduit cette thèse à intégrer des nouvelles méthodologies économétriques et à changer partiellement son objet, en mesurant aussi la soutenabilité externe. La thèse de F-H constitue un cas exemplaire d’intégration de l’analyse théorique et d’analyse empirique.

  20. Optimization for the Production of Surfactin with a New Synergistic Antifungal Activity

    Science.gov (United States)

    Liu, Mei; Dai, Huanqin; Song, Fuhang; Yu, Zhenyan; Wang, Shujin; Hu, Jiangchun; Kokare, Chandrakant R.; Zhang, Lixin

    2012-01-01

    Background Two of our long term efforts are to discover compounds with synergistic antifungal activity from metabolites of marine derived microbes and to optimize the production of the interesting compounds produced by microorganisms. In this respect, new applications or mechanisms of already known compounds with a high production yield could be continually identified. Surfactin is a well-known lipopeptide biosurfactant with a broad spectrum of antimicrobial and antiviral activity; however, there is less knowledge on surfactin’s antifungal activity. In this study, we investigated the synergistic antifungal activity of C15-surfactin and the optimization of its production by the response surface method. Methodology/Principal Findings Using a synergistic antifungal screening model, we found that the combination of C15-surfactin and ketoconazole (KTC) showed synergistic antifungal effect on Candida albicans SC5314 when the concentrations of C15-surfactin and KTC were 6.25 µg/mL and 0.004 µg/mL, respectively. These concentrations were lower than their own efficient antifungal concentrations, which are >100 µg/mL and 0.016 µg/mL, respectively. The production of C15-surfactin from Bacillus amyloliquefaciens was optimized by the response surface methodology in shaker flask cultivation. The Plackett-Burman design found sucrose, ammonium nitrate and NaH2PO4.2H2O to have significant effects on C15-surfactin production. The optimum values of the tested variables were 21.17 g/L sucrose, 2.50 g/L ammonium nitrate and 11.56 g/L NaH2PO4·2H2O. A production of 134.2 mg/L, which were in agreement with the prediction, was observed in a verification experiment. In comparison to the production of original level (88.6 mg/L), a 1.52-fold increase had been obtained. Conclusion/Significance This work first found that C15-surfactin was an efficient synergistic antifungal agent, and demonstrated that response surface methodology was an effective method to improve the production of C15

  1. Optimization for the production of surfactin with a new synergistic antifungal activity.

    Directory of Open Access Journals (Sweden)

    Xiangyang Liu

    Full Text Available Two of our long term efforts are to discover compounds with synergistic antifungal activity from metabolites of marine derived microbes and to optimize the production of the interesting compounds produced by microorganisms. In this respect, new applications or mechanisms of already known compounds with a high production yield could be continually identified. Surfactin is a well-known lipopeptide biosurfactant with a broad spectrum of antimicrobial and antiviral activity; however, there is less knowledge on surfactin's antifungal activity. In this study, we investigated the synergistic antifungal activity of C(15-surfactin and the optimization of its production by the response surface method.Using a synergistic antifungal screening model, we found that the combination of C(15-surfactin and ketoconazole (KTC showed synergistic antifungal effect on Candida albicans SC5314 when the concentrations of C(15-surfactin and KTC were 6.25 µg/mL and 0.004 µg/mL, respectively. These concentrations were lower than their own efficient antifungal concentrations, which are >100 µg/mL and 0.016 µg/mL, respectively. The production of C(15-surfactin from Bacillus amyloliquefaciens was optimized by the response surface methodology in shaker flask cultivation. The Plackett-Burman design found sucrose, ammonium nitrate and NaH(2PO(4 x 2H(2O to have significant effects on C(15-surfactin production. The optimum values of the tested variables were 21.17 g/L sucrose, 2.50 g/L ammonium nitrate and 11.56 g/L NaH(2PO(4·2H(2O. A production of 134.2 mg/L, which were in agreement with the prediction, was observed in a verification experiment. In comparison to the production of original level (88.6 mg/L, a 1.52-fold increase had been obtained.This work first found that C(15-surfactin was an efficient synergistic antifungal agent, and demonstrated that response surface methodology was an effective method to improve the production of C(15-surfactin.

  2. The antioxidant activity of kombucha fermented milk products with stinging nettle and winter savory

    Directory of Open Access Journals (Sweden)

    Vitas Jasmina S.

    2013-01-01

    Full Text Available This paper investigates the antioxidant activity of fermented milk products obtained by kombucha fermentation. Two starter cultures were used as follows: starter obtained after kombucha fermentation on sweetened stinging nettle extract; as well as starter obtained after kombucha fermentation on sweetened winter savory extract. The starters were added to milk with 0.8, 1.6 and 2.8% milk fat. Fermentation was carried out at 37, 40 and 43oC and stopped when the pH reached 4.5. Antioxidant activity to hydroxyl and DPPH radicals was monitored using response surface methodology. Kombucha fermented milk products with stinging nettle (KSN and with winter savory (KWS showed the same antioxidant response to hydroxyl and different response to DPPH radicals. Synergetic effect of milk fat and fermentation temperature to antioxidant activity to hydroxyl radicals for both types of kombucha fermented milk products (KSN and KWS was established. Optimum processing conditions in term of antioxidant activity are: milk fat around 2.8% and process temperature around 41 and 43°C for KSN and KWS respectively.

  3. Antibacterial and Antidiarrheal Activities of Plant Products against Enterotoxinogenic Escherichia coli

    Directory of Open Access Journals (Sweden)

    J. Daniel Dubreuil

    2013-11-01

    Full Text Available Enterotoxigenic Escherichia coli (ETEC produces two types of enterotoxins: heat-labile (LT and heat-stable (STa and STb. These molecules are involved in the induction of secretory diarrhea in animals including humans. This condition is currently treated using a fluid replacement therapy and antibiotics. This treatment is often not available to people in developing countries, and several die from the condition provoke by ETEC. Over the years, plants and plant extracts have been use as traditional medicine to treat various gastrointestinal ailments including diarrhea. Many of these plant products have been claimed to be active against diarrhea, however few have been extensively studied. The main objective of this review was to gather the scattered information on the antidiarrheal activities reported for various plant products on ETEC. This includes two major effects: (1 The inhibitory effect on bacterial growth or viability and (2 The interference with ETEC enterotoxins activity upon the intestinal epithelium. We will focus on plant products and extracts for which we have major indications of their biological activity against ETEC and their enterotoxins. Because Vibrio cholerae toxin (CT is structurally, antigenically and mechanistically related to LT, it will also be discussed in this review.

  4. Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.

    Science.gov (United States)

    Deshmukh, Hitesh S; Shaver, Colleen; Case, Lisa M; Dietsch, Maggie; Wesselkamper, Scott C; Hardie, William D; Korfhagen, Thomas R; Corradi, Massimo; Nadel, Jay A; Borchers, Michael T; Leikauf, George D

    2008-04-01

    Chronic obstructive pulmonary disease (COPD), a global public health problem, is characterized by progressive difficulty in breathing, with increased mucin production, especially in the small airways. Acrolein, a constituent of cigarette smoke and an endogenous mediator of oxidative stress, increases airway mucin 5, subtypes A and C (MUC5AC) production; however, the mechanism remains unclear. In this study, increased mMUC5AC transcripts and protein were associated with increased lung matrix metalloproteinase 9 (mMMP9) transcripts, protein, and activity in acrolein-exposed mice. Increased mMUC5AC transcripts and mucin protein were diminished in gene-targeted Mmp9 mice [Mmp9((-/-))] or in mice treated with an epidermal growth factor receptor (EGFR) inhibitor, erlotinib. Acrolein also decreased mTissue inhibitor of metalloproteinase protein 3 (an MMP9 inhibitor) transcript levels. In a cell-free system, acrolein increased pro-hMMP9 cleavage and activity in concentrations (100-300 nM) found in sputum from subjects with COPD. Acrolein increased hMMP9 transcripts in human airway cells, which was inhibited by an MMP inhibitor, EGFR-neutralizing antibody, or a mitogen-activated protein kinase (MAPK) 3/2 inhibitor. Together these findings indicate that acrolein can initiate cleavage of pro-hMMP9 and EGFR/MAPK signaling that leads to additional MMP9 formation. Augmentation of hMMP9 activity, in turn, could contribute to persistent excessive mucin production.

  5. Chemical Compositions and Antioxidant Activities of Polysaccharides from the Sporophores and Cultured Products of Armillaria mellea

    Directory of Open Access Journals (Sweden)

    Shanshan Zhang

    2015-03-01

    Full Text Available Armillaria mellea is a traditional Chinese medicinal and edible mushroom. Many cultured products of A. mellea have been used to develop commercial medicines in recent years. The chemical composition and activities of the major bioactive chemical components—polysaccharides—may be different because of differences in the raw materials used. Four polysaccharides (SP, CMP, CFBP and CFMP were obtained from wild sporophores and cultured products (including mycelia, fermentation broth and fermentation mixture of A. mellea. Their yields, carbohydrate contents, monosaccharide compositions, FT-IR spectra, NMR spectroscopy and antioxidant activities were investigated. All of the polysaccharides were composed of xylose, glucose and galactose without protein. Glucose was the dominant monosaccharide in SP, CMP and CFMP, whereas galactose was the dominant monosaccharide in CFBP. SP and CMP showed higher scavenging DPPH• and ABTS•+ activities and reducing power among four polysaccharides. The carbohydrate content and corresponding glucose percentage were positive influences on the antioxidant activities, whereas the corresponding xylose and galactose percentage were negative influences. A. mellea polysaccharides are potential natural antioxidants. Polysaccharides from cultured products, especially mycelia, are good substitutes for SP and are also potential sources for both dietary supplements and food industries.

  6. Chemical compositions and antioxidant activities of polysaccharides from the sporophores and cultured products of Armillaria mellea.

    Science.gov (United States)

    Zhang, Shanshan; Liu, Xiaoqian; Yan, Lihua; Zhang, Qiwei; Zhu, Jingjing; Huang, Na; Wang, Zhimin

    2015-03-31

    Armillaria mellea is a traditional Chinese medicinal and edible mushroom. Many cultured products of A. mellea have been used to develop commercial medicines in recent years. The chemical composition and activities of the major bioactive chemical components-polysaccharides-may be different because of differences in the raw materials used. Four polysaccharides (SP, CMP, CFBP and CFMP) were obtained from wild sporophores and cultured products (including mycelia, fermentation broth and fermentation mixture) of A. mellea. Their yields, carbohydrate contents, monosaccharide compositions, FT-IR spectra, NMR spectroscopy and antioxidant activities were investigated. All of the polysaccharides were composed of xylose, glucose and galactose without protein. Glucose was the dominant monosaccharide in SP, CMP and CFMP, whereas galactose was the dominant monosaccharide in CFBP. SP and CMP showed higher scavenging DPPH• and ABTS•+ activities and reducing power among four polysaccharides. The carbohydrate content and corresponding glucose percentage were positive influences on the antioxidant activities, whereas the corresponding xylose and galactose percentage were negative influences. A. mellea polysaccharides are potential natural antioxidants. Polysaccharides from cultured products, especially mycelia, are good substitutes for SP and are also potential sources for both dietary supplements and food industries.

  7. Research regarding biodegradable properties of food polymeric products under microorganism activity

    Science.gov (United States)

    Opran, Constantin; Lazar, Veronica; Fierascu, Radu Claudiu; Ditu, Lia Mara

    2018-02-01

    Aim of this research is the structural analysis by comparison of the biodegradable properties of two polymeric products made by non-biodegradable polymeric material (polypropylene TIPPLEN H949 A) and biodegradable polymeric material (ECOVIO IS 1335), under microorganism activity in order to give the best solution for the manufacture of food packaging biodegradable products. It presents the results of experimental determinations on comparative analysis of tensile strength for the two types of polymers. The sample weight variations after fungal biodegradation activity revealed that, after 3 months, there are no significant changes in polymeric substratum for non-biodegradable polymeric. The microscopically analysis showed that the fungal filaments did not strongly adhered on the non-biodegradable polymeric material, instead, both filamentous fungi strains adhered and covered the surface of the biodegradable sample with germinated filamentous conidia. The spectral analysis of polymer composition revealed that non-biodegradable polymer polypropylene spectra are identical for control and for samples that were exposed to fungal activity, suggesting that this type of sample was not degraded by the fungi strains. Instead, for biodegradable polymer sample, it was observed significant structural changes across multiple absorption bands, suggesting enzyme activity manifested mainly by Aspergillus niger strain. Structural analysis of interdisciplinary research results, lead, to achieving optimal injection molded technology emphasizing technological parameters, in order to obtain food packaging biodegradable products.

  8. Air activity variations as estimation of inhalation dose for the gases fission products

    International Nuclear Information System (INIS)

    Mousavi Shirazi, A; Jahanfarnia, G.; Rahgoshay, M.; Aghanajafi, C.; Sardari, D.

    2008-01-01

    This article presents that dissolved impurities are responsible for water activity and the release of fission gases Radon and Thoron into the reactor hall atmosphere. In normal operation of the reactor at 400 kilowatts, wide fluctuations in airborne activity (gross beta) between 15,000-200,000 dpm/m 3 have been noticed. The aerosol concentration, reactor hall temperature, relative humidity and ventilation rate are the factors influencing the levels of airborne activity in the reactor hall atmosphere. These parameters are discussed in relation to the observed air activities. The diffusion coefficient of the decay products and the unattached fraction of the decay products are necessary parameters for the estimation of lung dose. These have been measured. Internal exposure results from the deposition of radioactive material within the body through inhalation, ingestion and absorption. A recent study has indicated that inhalation is the main route of entry, and nearly 75% of the cases of internal contamination are attributable to inhalation. It has been demonstrated that the inert fission gases like Radon and Thoron do not contribute significantly to the dose due to inhalation to the working personnel in reactors, but their decay products which are particulate β emitters, contribute significant inhalation dose

  9. Effect of process variables on the production of Polyhydroxyalkanoates by activated sludge

    Directory of Open Access Journals (Sweden)

    Mokhtarani Nader

    2012-09-01

    Full Text Available Abstract Polyhydroxyalkanoates are known to be temporarily stored by microorganisms in activated sludge, especially in anaerobic-aerobic processes. Due to the problems resulted from the disposals of plastic wastes and excess sludge of wastewater treatment plants, the production of polyhydroxyalkanoates by treating activated sludge and determining the effect of process variables were the main issues of this paper. In this research, an anaerobic-aerobic sequencing batch reactor was used to make microorganism adapted and a batch aerobic reactor was used for enriching them. The variables affecting polyhydroxyalkanoates production including aeration time, sludge retention time, and volatile fatty acids concentration of the influent in sequencing batch reactor, and also carbon to nitrogen ratio and cultivation time in polymer production reactor, were investigated using Taguchi statistical approach to determine optimum conditions. The maximum polymer production of 29% was achieved at sludge retention time of 5–10 days, aeration time of 2 hours, supplementation of 40% of volatile fatty acids in the influent and increasing of carbon to nitrogen ratio of polymer production reactor to above 25 g/g. Based on the results, in optimum conditions, the volatile fatty acids concentration which increased the production of polyhydroxyalkanoates up to 49% was the most effective variable. Carbon to nitrogen ratio, sludge retention time and aeration time were ranked as the next affecting parameters. Although the polyhydroxyalkanoates content achieved in present study is much lower than that by pure culture, but the proposed method may still serve well as an environmental friendly means to convert waste into valuable product.

  10. Effect of Process Variables on the Production of Polyhydroxyalkanoates by Activated Sludge

    Directory of Open Access Journals (Sweden)

    Nader Mokhtarani

    2012-09-01

    Full Text Available Polyhydroxyalkanoates are known to be temporarily stored by microorganisms in activated sludge, especially in anaerobic-aerobic processes. Due to the problems resulted from the disposals of plastic wastes and excess sludge of wastewater treatment plants, the production of polyhydroxyalkanoates by treating activated sludge anddetermining the effect of process variables were the main issues of this paper. In this research, an anaerobic-aerobic sequencing batch reactor was used to make microorganism adapted and a batch aerobic reactor was used for enriching them. The variables affecting polyhydroxyalkanoates production including aeration time, sludge retention time, and volatile fatty acids concentration of the influent in sequencing batch reactor, and also carbon to nitrogenratio and cultivation time in polymer production reactor, were investigated using Taguchi statistical approach to determine optimum conditions. The maximum polymer production of 29% was achieved at sludge retention time of 5–10 days, aeration time of 2 hours, supplementation of 40% of volatile fatty acids in the influent and increasing of carbon to nitrogen ratio of polymer production reactor to above 25 g/g. Based on the results, in optimum conditions, the volatile fatty acids concentration which increased the production of polyhydroxyalkanoates up to 49% was the most effective variable. Carbon to nitrogen ratio, sludge retention time and aeration time were ranked as the next affecting parameters. Although the polyhydroxyalkanoates content achieved in present study is muchlower than that by pure culture, but the proposed method may still serve well as an environmental friendly means to convert waste into valuable product.

  11. The Siderophore Product Ornibactin Is Required for the Bactericidal Activity of Burkholderia contaminans MS14.

    Science.gov (United States)

    Deng, Peng; Foxfire, Adam; Xu, Jianhong; Baird, Sonya M; Jia, Jiayuan; Delgado, Keren H; Shin, Ronald; Smith, Leif; Lu, Shi-En

    2017-04-15

    Burkholderia contaminans MS14 was isolated from soil in Mississippi. When it is cultivated on nutrient broth-yeast extract agar, the colonies exhibit bactericidal activity against a wide range of plant-pathogenic bacteria. A bacteriostatic compound with siderophore activity was successfully purified and was determined by nuclear magnetic resonance spectroscopy to be ornibactin. Isolation of the bactericidal compound has not yet been achieved; therefore, the exact nature of the bactericidal compound is still unknown. During an attempt to isolate the bactericidal compound, an interesting relationship between the production of ornibactin and the bactericidal activity of MS14 was characterized. Transposon mutagenesis resulted in two strains that lost bactericidal activity, with insertional mutations in a nonribosomal peptide synthetase (NRPS) gene for ornibactin biosynthesis and a luxR family transcriptional regulatory gene. Coculture of these two mutant strains resulted in restoration of the bactericidal activity. Furthermore, the addition of ornibactin to the NRPS mutant restored the bactericidal phenotype. It has been demonstrated that, in MS14, ornibactin has an alternative function, aside from iron sequestration. Comparison of the ornibactin biosynthesis genes in Burkholderia species shows diversity among the regulatory elements, while the gene products for ornibactin synthesis are conserved. This is an interesting observation, given that ornibactin is thought to have the same defined function within Burkholderia species. Ornibactin is produced by most Burkholderia species, and its role in regulating the production of secondary metabolites should be investigated. IMPORTANCE Identification of the antibacterial product from strain MS14 is not the key feature of this study. We present a series of experiments that demonstrate that ornibactin is directly involved in the bactericidal phenotype of MS14. This observation provides evidence for an alternative function for

  12. Mineral composition of fruit by-products evaluated by neutron activation analysis

    International Nuclear Information System (INIS)

    Gabriela de Matuoka e Chiocchetti; Nadai Fernandes de, E.A.; Macio Arruda Bacchi; Rogerio Augusto Pazim; Silvana Regina Vicino Sarries; Thais Melega Tome

    2013-01-01

    Brazil is one of the largest producers of fruits cropping 40 million tons per year. In agro-food processing, approximately 50 % of raw material is discarded generating large amounts of by-products. The lack of information on the nutritional quality of agroindustrial by-products precludes their potential use in the manufacture of food products accessible to all. In this context, the objective of this work was to investigate the nutritional quality of by-products of the industrial processing of fruits. Samples of bagasse, peel and seeds of several fruits (banana, camu camu, coconut, cupuacu, guava, jackfruit, mango, orange, papaya, pineapple, and soursop) were analysed by neutron activation analysis for the determination of Br, Ca, Co, Cr, Cs, Fe, K, La, Na, Rb, Sc and Zn. In general, higher levels of minerals were found in the by-products rather than in the pulps of fruits. This indicates that the use of the by-products should be encouraged, thereby reducing the economic and environmental impact of waste generated by agroindustrial processing. (author)

  13. Radiation tolerant passive and active optical fiber products for use in space environments

    Science.gov (United States)

    Hill, Mark; Hankey, Judith; Gray, Rebecca

    2017-11-01

    This paper reports the radiation performance results of several new product types designed for high radiation environments. The products tested include radiation hardened highly birefringent (HiBi) passive products for polarised applications and radiation tolerant active erbium doped fiber products for amplifiers. Radiation hardened, short beatlength HiBi fiber products have been developed for high accuracy polarisation maintaining (PM) gyros and sensors at both 1310nm and 1550nm operation in the space environment. The fibers have been tested up to 5kGy (500krad) - levels which could be expected in extreme, extra-terrestrial space environments. Results show a consistently low Radiation Induced Attenuation (RIA) of fibers are intended for use in multichannel amplifiers in optical intersatellite communications. The structure of the fibers have been designed to deliver an accelerated recovery of radiation damage through photo-annealing using only the residual energy already available in an amplifier using a 980nm pumping regime. These products have been tested up to 200Gy (20krad) - levels which can be expected in Earth orbit environments over a 20-30 mission lifetime. Results show up to 100% recovery under continuous use for dose rates of 0.11rad/hr. It has also been demonstrated through analysis of the optical spectral output that this effect reverses the gain tilt, or spectral narrowing, induced by radiation damage through the C and L band. These combined fiber characteristics allow performance stability of the amplifier over the lifetime of the space mission.

  14. Mass Spectrometric Collisional Activation and Product Ion Mobility of Human Serum Neutral Lipid Extracts

    Science.gov (United States)

    Hankin, Joseph A.; Barkley, Robert M.; Zemski-Berry, Karin; Deng, Yiming; Murphy, Robert C.

    2016-01-01

    A novel method for lipid analysis called CTS (collisional activation and traveling wave mass spectrometry) involving tandem mass spectrometry of all precursor ions with ion mobility determinations of all product ions was applied to a sample of human serum. The resulting four dimensional data set (precursor ion, product ion, ion mobility values, and intensity) was found to be useful for characterization of lipids as classes as well as identification of specific species. Utilization of ion mobility measurements of the product ions is a novel approach for lipid analysis. The trends and patterns of product mobility values when visually displayed yield information on lipid classes and specific species independent of mass determination. The collection of a comprehensive set of data that incorporates all precursor-product relationships combined with ion mobility measurements of all products enables data analysis where different molecular properties can be juxtaposed and analyzed to assist with class and species identification. Overall, CTS is powerful, specific, and comprehensive method for lipid analysis. PMID:27213895

  15. Deterrent activity of hops flavonoids and their derivatives against stored product pests.

    Science.gov (United States)

    Jackowski, J; Popłoński, J; Twardowska, K; Magiera-Dulewicz, J; Hurej, M; Huszcza, E

    2017-10-01

    Five flavonoids from hops, two of their derivatives, along with naringenin used as a model compound, were tested for their antifeedant activity against three coleopteran stored product pests: Sitophilus granarius L., Tribolium confusum Duv. and Trogoderma granarium Everts. The introduction, into the tested flavonoid molecules, of additional structural fragments such as prenyl or dimethylpyran moiety, is proposed to significantly alter the deterrent activity of the compounds. The prenyl moiety in flavonoids increased the deterrent activity of these compounds in all three of the grain feeding species used in the tests. It is also concluded that the introduction of dimethylpyran moiety to the flavonoid structure increases its deterrent activity in S. granarius and T. confusum, but in one of the test insects, T. granarium, an increased feeding was observed in response to the introduction of dimethylpyran moiety to the flavonoid structure.

  16. Pregnancy enhances the sensitivity of glomerular ecto-adenosine triphosphate-diphosphohydrolase to products of activated polymorphonuclear leukocytes

    NARCIS (Netherlands)

    Faas, MM; Bakker, WW; Baller, JFW; Schuiling, GA

    To test the hypothesis that pregnancy enhances the sensitivity of glomerular ecto-adenosine triphosphate-diphosphohydrolase to products of activated polymorphonuclear leukocytes, cryostat-cut kidney sections of pregnant and cycling rats were exposed to activated polymorphonuclear leukocytes and

  17. Mesure et déterminants de l'efficacité technique des pisciculteurs du ...

    African Journals Online (AJOL)

    Fish farming can contribute to reduce the imports and induce income diversification in rural areas. In recent years, there has been an increase in the investments by young people in fish farming in Benin. This study aimed at measuring the technical efficiency of Benin's fish farms. The stochastic frontier production was ...

  18. Endothelial production of MCP-1: modulation by heparin and consequences for mononuclear cell activation.

    Science.gov (United States)

    Douglas, M S; Ali, S; Rix, D A; Zhang, J G; Kirby, J A

    1997-12-01

    Heparin is a polyanionic glycosaminoglycan (GAG) that can bind with high affinity to a range of cytokines including interferon-gamma (IFN-gamma) and members of the chemokine superfamily. This GAG also possesses immunomodulatory activity in vivo and can antagonize the capacity of IFN-gamma to induce class II MHC antigen expression, and to up-regulate intercellular adhesion molecule-1, by cultured endothelial cells. Previous studies have shown that binding to cell-surface heparan sulphate is essential for optimal activity of IFN-gamma and that free heparin competitively inhibits this sequestration process. The present study was performed to increase our understanding of the immunosuppressive activity of heparin by investigation of potential antagonism of the production and function of monocyte chemotactic peptide-1 (MCP-1), a chemokine important for mononuclear leucocyte recruitment across vascular endothelium. It was found that mixture of heparin with IFN-gamma inhibited up-regulation of the signal transducer and activator of transcription protein, STAT-1 produced normally by treatment of endothelial cells with IFN-gamma. An inhibition of MCP-1 production was observed that was specifically caused by mixture of IFN-gamma with heparin-like, and therefore cytokine-binding, GAGs. It was also shown that mixture of heparin-like GAGs with MCP-1 inhibited the rapid tyrosine phosphorylation of phosphatidylinositol 3-kinase which is normally produced by treatment of mononuclear leucocytes with this chemokine. Blockade of this intracellular signalling event was associated with a reduction in the normal transendothelial migration response towards MCP-1. Results from this study indicate that soluble, heparin-like GAGs can block IFN-gamma-dependent up-regulation of MCP-1 production by cultured endothelial cells, and can also antagonize the leucocyte-activating and migration-promoting properties of pre-existing MCP-1. These activities may contribute to the immunomodulatory

  19. Fluency-dependent cortical activation associated with speech production and comprehension in second language learners.

    Science.gov (United States)

    Shimada, K; Hirotani, M; Yokokawa, H; Yoshida, H; Makita, K; Yamazaki-Murase, M; Tanabe, H C; Sadato, N

    2015-08-06

    This functional magnetic resonance imaging (fMRI) study investigated the brain regions underlying language task performance in adult second language (L2) learners. Specifically, we identified brain regions where the level of activation was associated with L2 fluency levels. Thirty Japanese-speaking adults participated in the study. All participants were L2 learners of English and had achieved varying levels of fluency, as determined by a standardized L2 English proficiency test, the Versant English Test (Pearson Education Inc., 2011). When participants performed the oral sentence building task from the production tasks administered, the dorsal part of the left inferior frontal gyrus (dIFG) showed activation patterns that differed depending on the L2 fluency levels: The more fluent the participants were, the more dIFG activation decreased. This decreased activation of the dIFG might reflect the increased automaticity of a syntactic building process. In contrast, when participants performed an oral story comprehension task, the left posterior superior temporal gyrus (pSTG) showed increased activation with higher fluency levels. This suggests that the learners with higher L2 fluency were actively engaged in post-syntactic integration processing supported by the left pSTG. These data imply that L2 fluency predicts neural resource allocation during language comprehension tasks as well as in production tasks. This study sheds light on the neural underpinnings of L2 learning by identifying the brain regions recruited during different language tasks across different modalities (production vs. comprehension). Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Brazilian natural fiber (jute as raw material for activated carbon production

    Directory of Open Access Journals (Sweden)

    CARLA F.S. ROMBALDO

    2014-12-01

    Full Text Available Jute fiber is the second most common natural cellulose fiber worldwide, especially in recent years, due to its excellent physical, chemical and structural properties. The objective of this paper was to investigate: the thermal degradation of in natura jute fiber, and the production and characterization of the generated activated carbon. The production consisted of carbonization of the jute fiber and activation with steam. During the activation step the amorphous carbon produced in the initial carbonization step reacted with oxidizing gas, forming new pores and opening closed pores, which enhanced the adsorptive capacity of the activated carbon. N2 gas adsorption at 77K was used in order to evaluate the effect of the carbonization and activation steps. The results of the adsorption indicate the possibility of producing a porous material with a combination of microporous and mesoporous structure, depending on the parameters used in the processes, with resulting specific surface area around 470 m2.g–1. The thermal analysis indicates that above 600°C there is no significant mass loss.

  1. Low Water Activity Induces the Production of Bioactive Metabolites in Halophilic and Halotolerant Fungi

    Directory of Open Access Journals (Sweden)

    Nina Gunde-Cimerman

    2010-12-01

    Full Text Available The aim of the present study was to investigate indigenous fungal communities isolated from extreme environments (hypersaline waters of solar salterns and subglacial ice, for the production of metabolic compounds with selected biological activities: hemolysis, antibacterial, and acetylcholinesterase inhibition. In their natural habitats, the selected fungi are exposed to environmental extremes, and therefore the production of bioactive metabolites was tested under both standard growth conditions for mesophilic microorganisms, and at high NaCl and sugar concentrations and low growth temperatures. The results indicate that selected halotolerant and halophilic species synthesize specific bioactive metabolites under conditions that represent stress for non-adapted species. Furthermore, adaptation at the level of the chemical nature of the solute lowering the water activity of the medium was observed. Increased salt concentrations resulted in higher hemolytic activity, particularly within species dominating the salterns. The appearance of antibacterial potential under stress conditions was seen in the similar pattern of fungal species as for hemolysis. The active extracts exclusively affected the growth of the Gram-positive bacterium tested, Bacillus subtilis. None of the extracts tested showed inhibition of acetylcholinesterase activity.

  2. Development of an accelerator driven neutron activator for medical radioisotope production

    Energy Technology Data Exchange (ETDEWEB)

    Abbas, Kamel [Via Fermi 2749, I-21020 Ispra (Italy)], E-mail: kamel.abbas@jrc.it; Buono, Stefano; Burgio, Nunzio; Cotogno, Giulio; Gibson, Neil; Maciocco, Luca; Mercurio, Giovanni; Santagata, Alfonso; Simonelli, Federica; Tagziria, Hamid [Via Fermi 2749, I-21020 Ispra (Italy)

    2009-04-01

    A compact, accelerator driven, neutron activator based on a modified version of the Adiabatic Resonance Crossing (ARC) concept has been developed, with the aim of efficiently utilising ion-beam generated neutrons for the production of radioactive nanoparticles for brachytherapy. Extensive Monte Carlo simulations have been carried out to optimise the design of the activator, which is based on a hybrid approach, coupling a lead buffer and a graphite reflector. Computational Fluid Dynamic methods have been used for the thermal-hydraulic design of the neutron-generating beryllium target to ensure efficient water cooling under high proton beam currents. The facility has been tested under various experimental configurations, and the activation yields of different materials, measured with {gamma}-spectrometry techniques, have been compared with theoretical predictions. In this paper the main elements of the activator are described, and calculated and measured results for pure Au, Mo, Ho, and Re foils as well as for Re and Ho nanoparticle samples are presented. A satisfactory agreement between experiment and theory was found, confirming that the improved ARC activator developed in this work is suitable for isotope production for certain applications such as brachytherapy.

  3. Demonstration of physical phenomenas and scavenging activity from d-psicose and methionine maillard reaction products

    Directory of Open Access Journals (Sweden)

    Arum Tiyas Suminar

    2017-01-01

    Full Text Available Maillard reaction has been well understood as a non-enzymatic reaction between reducing sugars and amino acids to generate the Maillard reaction products (MRPs. This study is aimed to demonstrate the browning intensity, color development, spectra measurements, scavenging activity, and the correlation between browning intensity and scavenging activity of the MRPs generated from D-Psicose and Methionine (Psi-Met at 50℃. The browning intensity of MRPs was investigated based on the absorbance using spectrophotometer at 420 nm, the color development was observed using digital colorimeter to gained L*a*b* value then calculated as browning index, the spectra development was analyzed using spectrophotometer at 190 - 750 nm, and the scavenging activity was determined with ABTS method using spectrophotometer at 734 nm. The browning intensity, color development, and scavenging activity were improved along with the increase in heating process. Based on spectra analysis, MRPs from Psi-Met was initially detected at 21 h and Psi at 24 h of heating treatment, which indicating that Psi-Met have faster and better reaction than Psi during heating process. Positive non-linear and significant correlation between browning intensity and scavenging activity were assigned. This finding may provide beneficial information of D-psicose and MRPs to the next scientific research and to the food industries which applies MRPs in their products.

  4. Heat production and quantitative oxidation of nutrients by physical activity in humans

    DEFF Research Database (Denmark)

    Thorbek, G; Chwalibog, André; Jakobsen, K

    1994-01-01

    The effect of physical activity on heat production and oxidation of nutrients was measured by means of indirect calorimetry. The experiment included 6 male and 4 female healthy subjects who, during a 24-hour stay in the respiration chambers, performed, in the morning and afternoon, 15 min cycling...... of 66.2 kJ by cycling caused on average a heat increment of 309 kJ, yielding the mean energetic efficiency for the performed work of 0.22. The activity caused an increment of 11.5 g oxidized carbohydrate and 2.6 g oxidized fat....

  5. Production of activated carbon from Victorian brown coal and its application in gold recovery

    Energy Technology Data Exchange (ETDEWEB)

    Jobson, G.; Swinbourne, D.

    1985-01-01

    A research grant was awarded by the Coal Council of Victoria to support investigations into the manufacture of a Victorian brown coal-based activated carbon suitable for Carbon-in-Pulp (CIP) gold recovery operations. This project was started on 31.1.84 and was completed by 27.9.85. The general aim of this study was to develop the technology needed for production of an indigenous activated carbon which could be a substitute for the carbons presently imported for use in CIP operations. There was a considerable economic incentive to achieve a carbon based on an inexpensive resource such as Victorian brown coal.

  6. Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity

    DEFF Research Database (Denmark)

    Hjelmgaard, Thomas; Persson, T.; Rasmussen, Thomas Bovbjerg

    2003-01-01

    The synthesis of 5- and 3-(1'-hydroxyalkyl)-substituted 5H-furan-2-ones 4a-d and 8a-d as well as 5-alkylidene-5H-furan-2-ones 5a-d is described. A study of the structure-activity relationship of these furanone-based natural product analogues towards two different quorum sensing systems is reporte....... Although the synthesized compounds are not as potent quorum sensing inhibitors as some natural counterparts and a synthetic analogue hereof, interesting structure-activity relationships are seen....

  7. Future active layer dynamics and carbon dioxide production from thawing permafrost layers in Northeast Greenland

    DEFF Research Database (Denmark)

    Hollesen, Jørgen; Elberling, Bo; Jansson, P.E.

    2011-01-01

    from a moist permafrost soil in High-Arctic Greenland with observed heat production and carbon dioxide (CO2) release rates from decomposition of previously frozen organic matter. Observations show that the maximum thickness of the active layer at the end of the summer has increased 1 cm yr-1 since 1996......Thawing permafrost and the resulting mineralization of previously frozen organic carbon (C) is considered an important future feedback from terrestrial ecosystems to the atmosphere. Here, we use a dynamic process oriented permafrost model, the CoupModel, to link surface and subsurface temperatures......–105 cm as a result of a 2–6 °C warming. An additional increase in the maximum active layer thickness of a few centimetres may be expected due to heat production from decomposition of organic matter. Simulated future soil temperatures and water contents are subsequently used with measured basal soil...

  8. Sesquiterpenoids and Diterpenoids from the Wood of Cunninghamia konishii and Their Inhibitory Activities against NO Production.

    Science.gov (United States)

    Chang, Chi-I; Chen, Chien-Chih; Chao, Che-Yi; Wang, Sheng-Yang; Chang, Hsun-Shuo; Sung, Ping-Jyun; Huang, Guan-Jhong; Li, Yen-Cheng; Kuo, Yueh-Hsiung

    2016-04-13

    Three new sesquiterpenoids, 2α-hydroxy-3,3,6α,9β-tetramethyltricyclo[4,3,2(1,4)]undecane (1), 11-acetoxyeudesman-4β-ol (4), and 2α,3β-dihydroxy-4β-methyl-6,8,10-cadinatriene (6), four known sesquiterpenoids (2, 3, 5, and 7), together with eight known diterpenoids (8-15), were isolated from the wood of Cunninghamia konishii. Their structures were determined by detailed analysis of spectroscopic data and comparison with the data of known analogues. Four sesquiterpenoids (1, 4, 5, and 6) and all the diterpenoids (8-15) were evaluated for inhibition of nitric oxide production in lipopolysaccharides (LPS)-activated RAW 264.7 macrophages and the results showed that compounds 10 and 15 exhibited moderate inhibitory activities against nitric oxide production.

  9. Production and application of therapeutic radioisotopes. Activity on the related nuclear reaction data

    International Nuclear Information System (INIS)

    Tarkanyi, F.

    2002-01-01

    Full text: The Charged Particle Nuclear Data (CPND) Group in the ATOMKI has been involved in measurement, compilation, evaluation and application of nuclear reaction data for more than 15 years. The main field of activity is charged particle induced reactions. The research is mainly focused on non-energy related applications: medical radioisotope production, monitoring the parameters of charged particle beams, thin layer activation to control wear and corrosion. Last years we have started to extend our activities to measurements of fast neutron reaction data and charged particle reaction data related to waste transmutation. The CPND Group itself has extended experimental experience at the Debrecen MGC 20E cyclotron and at other accelerators in collaboration with universities in Hungary or laboratories in Germany (INC, Forschungszentrum Juelich), Belgium (Cyclotron Laboratory, Vrije Universiteit of Brussels), Japan (CYRIC, Tohoku University, Sendai and National Institute of Radiological Sciences, Chiba), Finland (Cyclotron Lab., Abo Akademi, Turku), Czech Republic (Nuclear Research Institute, Rez) and South-Africa (National Accelerator Centre, Faure). Activities in the field of compilation and data evaluation are done in close collaboration with IAEA in the frame of independent projects and of the Nuclear Reaction Data Center Network. Eight scientists (six physicists and two chemists) are contributing to the nuclear data project (most of them only part-time). An important field of the nuclear data activity actually lies in the medical radioisotope production. The members of ATOMKI CPND group are involved in every day radioisotope production of diagnostic radioisotopes for PET and SPECT. The team was also involved in the IAEA-CRP on development of a recommended database for production of diagnostic radioisotopes reactions for nuclear medicine by charged particle induced reactions and presently is engaged in the extension and upgrading of this database. In the field

  10. Brazilian Propolis: A Natural Product That Improved the Fungicidal Activity by Blood Phagocytes

    Science.gov (United States)

    Possamai, Muryllo Mendes; Honorio-França, Adenilda Cristina; Reinaque, Ana Paula Barcelos; França, Eduardo Luzia; Souto, Paula Cristina de Souza

    2013-01-01

    Natural product incorporation into microcarriers increases the bioavailability of these compounds, consequently improving their therapeutic properties. Natural products, particularly those from bees such as propolis, are widely used in popular medicine. Propolis is a powerful treatment for several diseases. In this context, the present study evaluated the effect of propolis Scaptotrigona sp. and its fractions, alone or adsorbed to polyethylene glycol (PEG) microspheres, on the activity of human phagocytes against Candida albicans. The results show that propolis exerts a stimulatory effect on these cells to assist in combating the fungus, especially as the crude extract is compared with the fractions. However, when incorporated into microspheres, these properties were significantly potentiated. These results suggest that propolis adsorbed onto PEG microspheres has immunostimulatory effects on phagocytes in human blood. Therefore, propolis may potentially be an additional natural product that can be used for a variety of therapies. PMID:23509737

  11. Trace element determination in beauty products by k0-instrumental neutron activation analysis

    International Nuclear Information System (INIS)

    Sneyers, L.; Verheyen, L.; Vermaercke, P.; Bruggeman, M.

    2009-01-01

    A recent study on trace elements in beauty products and cosmetics sold on the Asian market has shown the presence of high levels of U, Th and rare earth elements in so called 'Hormesis cosmetics'. For the purpose of comparison, some more information about trace elements in European cosmetics would be useful. In this paper the results obtained using k 0 -standardised Instrumental Neutron Activation Analysis (k 0 -INAA) for more than 20 trace elements in 20 different beauty products collected from the European market are presented. We found traces of Ba, As and Sb which is in breach with European legislation. For some of the other elements like Cr and Co further speciation is needed in order to evaluate their presence in beauty products. (author)

  12. Removal of the Fermentation Inhibitor, Furfural, Using Activated Carbon in Cellulosic-Ethanol Production

    KAUST Repository

    Zhang, Kuang

    2011-12-21

    Ethanol can be produced from lignocellulosic biomass through fermentation; however, some byproducts from lignocellulosics, such as furfural compounds, are highly inhibitory to the fermentation and can substantially reduce the efficiency of ethanol production. In this study, commercial and polymer-derived activated carbons were utilized to selectively remove the model fermentation inhibitor, furfural, from water solution during bioethanol production. The oxygen functional groups on the carbon surface were found to influence the selectivity of sorbents between inhibitors and sugars during the separation. After inhibitors were selectively removed from the broth, the cell growth and ethanol production efficiency was recovered noticeably in the fermentation. A sorption/desorption cycle was designed, and the sorbents were regenerated in a fixed-bed column system using ethanol-containing standard solution. Dynamic mass balance was obtained after running four or five cycles, and regeneration results were stable even after twenty cycles. © 2011 American Chemical Society.

  13. A computer code PACTOLE to predict activation and transport of corrosion products in a PWR

    International Nuclear Information System (INIS)

    Beslu, P.; Frejaville, G.; Lalet, A.

    1978-01-01

    Theoretical studies on activation and transport of corrosion products in a PWR primary circuit have been concentrated, at CEA on the development of a computer code : PACTOLE. This code takes into account the major phenomena which govern corrosion products transport: 1. Ion solubility is obtained by usual thermodynamics laws in function of water chemistry: pH at operating temperature is calculated by the code. 2. Release rates of base metals, dissolution rates of deposits, precipitation rates of soluble products are derived from solubility variations. 3. Deposition of solid particles is treated by a model taking into account particle size, brownian and turbulent diffusion and inertial effect. Erosion of deposits is accounted for by a semi-empirical model. After a review of calculational models, an application of PACTOLE is presented in view of analyzing the distribution of in core. (author)

  14. A procedure for the production of steel exhibiting a low specific activity of gamma emitters

    International Nuclear Information System (INIS)

    Dolenek, J.; Raska, P.; Kodrle, L. et al.

    1989-01-01

    Steel exhibiting low specific gamma activity can be obtained from a metallic charge containing liquid and solid pig iron produced from ores, sinters, coke, limestone and other components. This charge is worked up in a metallurgical fining unit using predetermined amounts of slag-forming substances such as lime, limestone and dolomite; fining ore can also be present. The smelt must be kept in constant motion. The pig iron smelt for the production of this steel contains 0.1-1.1% Si and 0.1-1.0% Mn. All equipment with which the charge and steel will come in contact must be free from remains of previous productions and, preferrably, fitted with new lining. This concerns runners, pig iron transportation mixers, ladles and the production unit. (P.A.)

  15. Decoding of articulatory gestures during word production using speech motor and premotor cortical activity.

    Science.gov (United States)

    Mugler, Emily M; Goldrick, Matthew; Rosenow, Joshua M; Tate, Matthew C; Slutzky, Marc W

    2015-01-01

    Brain-machine interfaces that directly translate attempted speech from the speech motor areas could change the lives of people with complete paralysis. However, it remains uncertain exactly how speech production is encoded in cortex. Improving this understanding could greatly improve brain-machine interface design. Specifically, it is not clear to what extent the different levels of speech production (phonemes, or speech sounds, and articulatory gestures, which describe the movements of the articulator muscles) are represented in the motor cortex. Using electrocorticographic (ECoG) electrodes on the cortical surface, we recorded neural activity from speech motor and premotor areas during speech production. We decoded both gestures and phonemes using the neural signals. Overall classification accuracy was higher for gestures than phonemes. In particular, gestures were better represented in the primary sensorimotor cortices, while phonemes were better represented in more anterior areas.

  16. MAG4 versus alternative techniques for forecasting active region flare productivity

    Science.gov (United States)

    Falconer, David A; Moore, Ronald L; Barghouty, Abdulnasser F; Khazanov, Igor

    2014-01-01

    MAG4 is a technique of forecasting an active region's rate of production of major flares in the coming few days from a free magnetic energy proxy. We present a statistical method of measuring the difference in performance between MAG4 and comparable alternative techniques that forecast an active region's major-flare productivity from alternative observed aspects of the active region. We demonstrate the method by measuring the difference in performance between the “Present MAG4” technique and each of three alternative techniques, called “McIntosh Active-Region Class,” “Total Magnetic Flux,” and “Next MAG4.” We do this by using (1) the MAG4 database of magnetograms and major flare histories of sunspot active regions, (2) the NOAA table of the major-flare productivity of each of 60 McIntosh active-region classes of sunspot active regions, and (3) five technique performance metrics (Heidke Skill Score, True Skill Score, Percent Correct, Probability of Detection, and False Alarm Rate) evaluated from 2000 random two-by-two contingency tables obtained from the databases. We find that (1) Present MAG4 far outperforms both McIntosh Active-Region Class and Total Magnetic Flux, (2) Next MAG4 significantly outperforms Present MAG4, (3) the performance of Next MAG4 is insensitive to the forward and backward temporal windows used, in the range of one to a few days, and (4) forecasting from the free-energy proxy in combination with either any broad category of McIntosh active-region classes or any Mount Wilson active-region class gives no significant performance improvement over forecasting from the free-energy proxy alone (Present MAG4). Key Points Quantitative comparison of performance of pairs of forecasting techniques Next MAG4 forecasts major flares more accurately than Present MAG4 Present MAG4 forecast outperforms McIntosh AR Class and total magnetic flux PMID:26213517

  17. Progress in fission product nuclear data. Information about activities in the field of measurements and compilations/evaluations of fission product nuclear data (FPND)

    International Nuclear Information System (INIS)

    Lammer, G.

    1978-07-01

    This is the fourth issue of a report series on Fission Product Nuclear Data (FPND) which is published by the Nuclear Data Section (NDS) of the International Atomic Energy Agency (IAEA). The purpose of this series is to inform scientists working on FPND, or using such data, about all activities in this field which are planned, ongoing, or have recently been completed. The main part of this report consists of unaltered original contributions which the authors have sent to IAEA/NDS. The types of activities being included in this report are measurements, compilations and evaluations of: Fission product yields (neutron induced and spontaneous fission); neutron reaction cross sections of fission products; data related to the radioactive decay of fission products; delayed neutron data of fission products; and lumped fission product data (decay heat, absorption etc.)

  18. An overview of the activated corrosion product reduction program for US power reactors

    International Nuclear Information System (INIS)

    Murphy, T.D.

    1977-01-01

    Recent studies have shown that radiation levels associated with reactor coolant components are increasing at US nuclear power plants. Recent experience also shows that occupational radiation exposure to personnel is also increasing. This paper discusses one aspect of reducing exposure to personnel, that is, recent developments in the reduction of existing corrosion product radioactivity in reactor coolant systems and the minimization of the formation and buildup of such activity.(orig.) [de

  19. Strategies for production of active eukaryotic proteins in bacterial expression system

    OpenAIRE

    Orawan Khow; Sunutcha Suntrarachun

    2012-01-01

    Bacteria have long been the favorite expression system for recombinant protein production. However, the flaw of the system is that insoluble and inactive proteins are co-produced due to codon bias, protein folding, phosphorylation, glycosylation, mRNA stability and promoter strength. Factors are cited and the methods to convert to soluble and active proteins are described, for example a tight control of Escherichia coli milieu, refolding from inclusion body and through fusion technology.

  20. Aureobasidium pullulans Fermented Feruloyl Oligosaccharide: Optimization of Production, Preliminary Characterization, and Antioxidant Activity

    OpenAIRE

    Xiaohong Yu; Zhenxin Gu

    2013-01-01

    Wheat bran (WB) was subjected to processing with Aureobasidium pullulans (A. pullulans) under selected conditions to partially break down the xylan into soluble products (mainly feruloyl oligosaccharides, FOs). The objective of this study was to investigate the technology for one-step fermentation of WB by A. pullulans without melanin secretion to produce FOs as well as to determine their structural features and antioxidant activity. Initial pH, inoculation quantity, and fermentation temperat...

  1. Microbial Consortium with High Cellulolytic Activity (MCHCA for enhanced biogas production.

    Directory of Open Access Journals (Sweden)

    Krzysztof ePoszytek

    2016-03-01

    Full Text Available The use of lignocellulosic biomass as a substrate in agricultural biogas plants is very popular and yields good results. However, the efficiency of anaerobic digestion, and thus biogas production, is not always satisfactory due to the slow or incomplete degradation (hydrolysis of plant matter. To enhance the solubilization of the lignocellulosic biomass various physical, chemical and biological pretreatment methods are used.The aim of this study was to select and characterize cellulose-degrading bacteria, and to construct a microbial consortium, dedicated for degradation of maize silage and enhancing biogas production from this substrate.Over one hundred strains of cellulose-degrading bacteria were isolated from: sewage sludge, hydrolyzer from an agricultural biogas plant, cattle slurry and manure. After physiological characterization of the isolates, sixteen strains (representatives of Bacillus, Providencia and Ochrobactrum genera were chosen for the construction of a Microbial Consortium with High Cellulolytic Activity, called MCHCA. The selected strains had a high endoglucanase activity (exceeding 0.21 IU/mL CMCase activity and a wide range of tolerance to various physical and chemical conditions. Lab-scale simulation of biogas production using the selected strains for degradation of maize silage was carried out in a two-bioreactor system, similar to those used in agricultural biogas plants.The obtained results showed that the constructed MCHCA consortium is capable of efficient hydrolysis of maize silage, and increases biogas production by even 38%, depending on the inoculum used for methane fermentation. The results in this work indicate that the mesophilic Microbial Consortium with High Cellulolytic Activity has a great potential for application on industrial scale in agricultural biogas plants.

  2. Search for related substances in market products containing enalapril maleate as the active principle.

    Science.gov (United States)

    Pilatti, C; Ercolano, I; Torre, M C; Chiale, C; Spinetto, M

    1999-06-01

    This study's main object was the determination of substances, by means of high-performance liquid chromatography (HPLC), that are related to enalapril maleate in medicinal tablets. The research was on products containing a 20 mg active principle with a 12-month delta t and on those batches near their expiration date with an enalapril maleate concentration of 10, 5, and 2.5 mg.

  3. Design and application of natural product derived probes for activity based protein profiling

    OpenAIRE

    Battenberg, Oliver Alexander

    2015-01-01

    The identification of new antibacterial protein targets by activity based protein profiling (ABPP) is an important approach to face the increasing emergence of resistant bacteria. The scope of this work focuses on three new strategies for the labeling of antibacterial protein-targets with natural product derived ABPP-probes: A.) Evaluation of the intrinsic photo-reactivity of α-pyrones and pyrimidones for use as photo-crosslinkers. B.) Synthesis of a benzophenone-tag that combines photo-cross...

  4. Energy recovery during advanced wastewater treatment: simultaneous estrogenic activity removal and hydrogen production through solar photocatalysis.

    Science.gov (United States)

    Zhang, Wenlong; Li, Yi; Wang, Chao; Wang, Peifang; Wang, Qing

    2013-03-01

    Simultaneous estrogenic activity removal and hydrogen production from secondary effluent were successfully achieved using TiO(2) microspheres modified with both platinum nanoparticles and phosphates (P-TiO(2)/Pt) for the first time. The coexistence of platinum and phosphate on the surface of TiO(2) microspheres was confirmed by transmission electron microscope, energy-dispersive X-ray and X-ray photoelectron spectroscopy analyses. P-TiO(2)/Pt microspheres showed a significantly higher photocatalytic activity than TiO(2) microspheres and TiO(2) powders (P25) for the removal of estrogenic activity from secondary effluent with the removal ratio of 100%, 58.2% and 48.5% in 200 min, respectively. Moreover, the marked production of hydrogen (photonic efficiency: 3.23 × 10(-3)) was accompanied by the removal of estrogenic activity only with P-TiO(2)/Pt as photocatalysts. The hydrogen production rate was increasing with decreased DO concentration in secondary effluent. Results of reactive oxygen species (ROS) evaluation during P-TiO(2)/Pt photocatalytic process showed that O(2)(-)and OH were dominant ROS in aerobic phase, while OH was the most abundant ROS in anoxic phase. Changes of effluent organic matter (EfOM) during photocatalysis revealed that aromatic, hydrophobic, and high molecular weight fractions of EfOM were preferentially transformed into non-humic, hydrophilic, and low MW fractions (e.g. aldehydes and carboxylic acids), which were continuously utilized as electron donors in hydrogen production process. Copyright © 2012 Elsevier Ltd. All rights reserved.

  5. Synthesis of furanone-based natural product analogues with quorum sensing antagonist activity

    DEFF Research Database (Denmark)

    Hjelmgaard, Thomas; Persson, T.; Rasmussen, Thomas Bovbjerg

    2003-01-01

    The synthesis of 5- and 3-(1'-hydroxyalkyl)-substituted 5H-furan-2-ones 4a-d and 8a-d as well as 5-alkylidene-5H-furan-2-ones 5a-d is described. A study of the structure-activity relationship of these furanone-based natural product analogues towards two different quorum sensing systems is reported...

  6. Hypothalamic peroxisome proliferator-activated receptor gamma regulates ghrelin production and food intake.

    Science.gov (United States)

    Li, Qingjie; Yu, Quan; Lin, Li; Zhang, Heng; Peng, Miao; Jing, Chunxia; Xu, Geyang

    2018-04-09

    Peroxisome proliferator-activated receptor-γ (PPARγ) regulates fatty acid storage, glucose metabolism, and food intake. Ghrelin, a gastric hormone, provides a hunger signal to the central nervous system to stimulate appetite. However, the effects of PPARγ on ghrelin production are still unclear. In the present study, the effects of PPARγ on ghrelin production were examined in lean- or high-fat diet-induced obese (DIO) C57BL/6J mice and mHypoE-42 cells, a hypothalamic cell line. 3rd intracerebroventricular injection of adenoviral-directed overexpression of PPARγ (Ad-PPARγ) reduced hypothalamic and plasma ghrelin, food intake in both lean C57BL/6J mice and diet-induced obese mice. These changes were associated with a significant increase in mechanistic target of rapamycin complex 1 (mTORC1) activity. Overexpression of PPARγ enhanced mTORC1 signaling and suppressed ghrelin production in cultured mHypoE-42 cells. Our results suggest that hypothalamic PPARγ plays a vital role in ghrelin production and food intake in mice. Copyright © 2018 Elsevier Ltd. All rights reserved.

  7. Effects of Flavonoids on Rumen Fermentation Activity, Methane Production, and Microbial Population

    Directory of Open Access Journals (Sweden)

    Ehsan Oskoueian

    2013-01-01

    Full Text Available This research was carried out to evaluate the effects of flavone, myricetin, naringin, catechin, rutin, quercetin, and kaempferol at the concentration of 4.5% of the substrate (dry matter basis on the rumen microbial activity in vitro. Mixture of guinea grass and concentrate (60 : 40 was used as the substrate. The results showed that all the flavonoids except naringin and quercetin significantly ( decreased the dry matter degradability. The gas production significantly ( decreased by flavone, myricetin, and kaempferol, whereas naringin, rutin, and quercetin significantly ( increased the gas production. The flavonoids suppressed methane production significantly (. The total VFA concentration significantly ( decreased in the presence of flavone, myricetin, and kaempferol. All flavonoids except naringin and quercetin significantly ( reduced the carboxymethyl cellulase, filter paperase, xylanase, and β-glucosidase activities, purine content, and the efficiency of microbial protein synthesis. Flavone, myricetin, catechin, rutin, and kaempferol significantly ( reduced the population of rumen microbes. Total populations of protozoa and methanogens were significantly ( suppressed by naringin and quercetin. The results of this research demonstrated that naringin and quercetin at the concentration of 4.5% of the substrate (dry matter basis were potential metabolites to suppress methane production without any negative effects on rumen microbial fermentation.

  8. Biological effects of activation products and other chemicals released from fusion power plants

    Energy Technology Data Exchange (ETDEWEB)

    Strand, J.A.; Poston, T.M.

    1976-09-01

    Literature reviews indicate that existing information is incomplete, often contradictory, and of questionable value for the prediction and assessment of ultimate impact from fusion-associated activation products and other chemical releases. It is still uncertain which structural materials will be used in the blanket and first wall of fusion power plants. However, niobium, vanadium, vanadium-chromium alloy, vanadium-titanium alloy, sintered aluminum product, and stainless steel have been suggested. The activation products of principal concern will be the longer-lived isotopes of /sup 26/Al, /sup 49/V, /sup 51/Cr, /sup 54/Mn, /sup 55/Fe, /sup 58/Co, /sup 60/Co, /sup 93/Nb, and /sup 94/Nb. Lithium released to the environment either during the mining cycle, from power plant operation or accident, may be in the form of a number of compound types varying in solubility and affinity for biological organisms. The effects of a severe liquid metal fire or explosion involving Na or K will vary according to inherent abiotic and biotic features of the affected site. Saline, saline-alkaline, and sodic soils of arid lands would be particularly susceptible to alkaline stress. Beryllium released to the environment during the mining cycle or reactor accident situation could be in the form of a number of compound types. Adverse effects to aquatic species from routine chemical releases (biocides, corrosion inhibitors, dissolution products) may occur in the discharge of both fission and fusion power plant designs.

  9. Optimization of keratinase production and enzyme activity using response surface methodology with Streptomyces sp7.

    Science.gov (United States)

    Tatineni, Radhika; Doddapaneni, Kiran Kumar; Potumarthi, Ravi Chandra; Mangamoori, Lakshmi Narasu

    2007-01-01

    A two-step response surface methodology (RSM) study was conducted for the optimization of keratinase production and enzyme activity from poultry feather by Streptomyces sp7. Initially different combinations of salts were screened for maximal production of keratinase at a constant pH of 6.5 and feather meal concentration of 5 g/L. A combination of K2HPO4, KH2PO4, and NaCl gave a maximum yield of keratinase (70.9 U/mL) production. In the first step of the RSM study, the selected five variables (feather meal, K2HPO4, KH2PO4, NaCl, and pH) were optimized by a 25 full-factorial rotatable central composite design (CCD) that resulted in 95 U/mL of keratinase production. The results of analysis of variance and regression of a second-order model showed that the linear effects of feather meal concentration (pNaCl (penzyme activity. These optima were pH 11.0, 45 degrees C, and 300 rpm.

  10. Compartmentalized system with membrane-bound glycerol kinase. Activity and product distribution versus asymmetrical substrate supply.

    Science.gov (United States)

    Girard, A; Merchie, B; Maïsterrena, B

    1991-03-15

    An artificial-membrane-bound glycerokinase chosen as a membrane-bound two-substrate-enzyme model has been used to separate two unequal compartments of a specially designed diffusion cell. An interesting feature is the asymmetry of compartments and the existence of a diffusion layer adjacent to only one face of the enzymic membrane. In such a situation the apparent enzyme activity and the product distribution in the system have been studied versus all the possibilities of combination of ATP and glycerol supply. Our approach has lead us to differentiate two different roles played by a diffusion layer adjacent to a permeable enzymic membrane. Depending on the spatial origin of the enzymic substrates (i.e. from which compartment they derive), the diffusion layer can play either the role of a passive additional resistance to that of the membrane or the role of a third compartment in which the reaction product can partially accumulate before splitting on both parts of the membrane. Our results mainly demonstrate that a membrane-bound enzyme activity and the resulting product distribution occurring in a compartmentalized system may be regulated by the cumulative effect due to the asymmetry in volumes of the compartments, the presence of a diffusion layer and the different possibilities of substrate supply. With the topography studied, which is close to that reported for many 'in vivo' situations, the product may be diffused lead to vectorial metabolism processes.

  11. Effects of Chlorophenoxy Herbicides and Their Main Transformation Products on DNA Damage and Acetylcholinesterase Activity

    Science.gov (United States)

    Benfeito, Sofia; Silva, Tiago; Garrido, Jorge; Andrade, Paula B.; Sottomayor, M. J.; Borges, Fernanda; Garrido, E. Manuela

    2014-01-01

    Persistent pesticide transformation products (TPs) are increasingly being detected among different environmental compartments, including groundwater and surface water. However, there is no sufficient experimental data on their toxicological potential to assess the risk associated with TPs, even if their occurrence is known. In this study, the interaction of chlorophenoxy herbicides (MCPA, mecoprop, 2,4-D and dichlorprop) and their main transformation products with calf thymus DNA by UV-visible absorption spectroscopy has been assessed. Additionally, the toxicity of the chlorophenoxy herbicides and TPs was also assessed evaluating the inhibition of acetylcholinesterase activity. On the basis of the results found, it seems that AChE is not the main target of chlorophenoxy herbicides and their TPs. However, the results found showed that the transformation products displayed a higher inhibitory activity when compared with the parent herbicides. The results obtained in the DNA interaction studies showed, in general, a slight effect on the stability of the double helix. However, the data found for 4-chloro-2-methyl-6-nitrophenol suggest that this transformation product can interact with DNA through a noncovalent mode. PMID:24795892

  12. A Tensor-Product-Kernel Framework for Multiscale Neural Activity Decoding and Control

    Science.gov (United States)

    Li, Lin; Brockmeier, Austin J.; Choi, John S.; Francis, Joseph T.; Sanchez, Justin C.; Príncipe, José C.

    2014-01-01

    Brain machine interfaces (BMIs) have attracted intense attention as a promising technology for directly interfacing computers or prostheses with the brain's motor and sensory areas, thereby bypassing the body. The availability of multiscale neural recordings including spike trains and local field potentials (LFPs) brings potential opportunities to enhance computational modeling by enriching the characterization of the neural system state. However, heterogeneity on data type (spike timing versus continuous amplitude signals) and spatiotemporal scale complicates the model integration of multiscale neural activity. In this paper, we propose a tensor-product-kernel-based framework to integrate the multiscale activity and exploit the complementary information available in multiscale neural activity. This provides a common mathematical framework for incorporating signals from different domains. The approach is applied to the problem of neural decoding and control. For neural decoding, the framework is able to identify the nonlinear functional relationship between the multiscale neural responses and the stimuli using general purpose kernel adaptive filtering. In a sensory stimulation experiment, the tensor-product-kernel decoder outperforms decoders that use only a single neural data type. In addition, an adaptive inverse controller for delivering electrical microstimulation patterns that utilizes the tensor-product kernel achieves promising results in emulating the responses to natural stimulation. PMID:24829569

  13. Influence Determination of Social Responsibility to the Productivity Enterprise Activity Level

    Directory of Open Access Journals (Sweden)

    Sergii Kavun

    2016-07-01

    Full Text Available The purpose of this paper is to develop a scientific and methodical approach for determination of the comprehensive social responsibility indicator in this paper based on estimation of influence degree for the economical, ecological, social and labour, standard and legal components. There is allowance for determining of some level of enterprise social responsibility. In addition, there is a basis for development some ways of their increasing. The essence of the used approach is clotting of the individual indicators set to four intermediate indicators of the economic, ecological, social and labor, standard and legal components, which can be boiled down to the generalizing activity productivity indicator based on the matrix and range approach. An economical and mathematical model of the social responsibility influence level to the enterprise activity productivity level, which is based on enterprise propose harmonization with the participants’ interests, was being built. The paper proposes the mathematical model, which allows detecting a necessary time period for enterprise activity productivity ensuring due to social responsibility implementation.

  14. Enhanced butanol production and reduced autolysin activity after chloramphenicol treatment of Clostridium acetobutylicum ATCC 824

    Energy Technology Data Exchange (ETDEWEB)

    Zhou Xiangdong; Traxler, R.W. (Rhode Island Univ., Kingston, RI (United States). Dept. of Food Science and Nutrition)

    1992-06-01

    Release of autolysin during the late exponential growth phase of Clostridium acetobutylicum resulted in early lysis of the culture and reduction of solvent formation. A simple and effective way of reducing autolysin activity and increasing solvent production is partial inhibition of protein synthesis with chloramphenicol (CAP). The extracellular autolytic activity in the culture, determined by following loss of turbidity of washed clostridial cells in 0.04 M sodium phosphate buffer at 37deg C, was decreased by 40% after CAP treatment. This caused an extension of cell viability by 12 h and an increase in butanol production by 30%. The optimal time of CAP addition was 12 h of incubation, and the optimal antibiotic concentration was 120 {mu}g/ml. The effects of CAP on the fermentation are due to the inhibition of protein synthesis leading to a decrease in autolysin level in the culture. The results obtained provide economic advantages for industrial production of solvents by minimizing autolysin activity and maximizing solvent yield during the critical solvent-producing phase. (orig.).

  15. Selective enrichment and production of highly urease active bacteria by non-sterile (open) chemostat culture.

    Science.gov (United States)

    Cheng, Liang; Cord-Ruwisch, Ralf

    2013-10-01

    In general, bioprocesses can be subdivided into naturally occurring processes, not requiring sterility (e.g., beer brewing, wine making, lactic acid fermentation, or biogas digestion) and other processes (e.g., the production of enzymes and antibiotics) that typically require a high level of sterility to avoid contaminant microbes overgrowing the production strain. The current paper describes the sustainable, non-sterile production of an industrial enzyme using activated sludge as inoculum. By using selective conditions (high pH, high ammonia concentration, and presence of urea) for the target bacterium, highly active ureolytic bacteria, physiologically resembling Sporosarcina pasteurii were reproducibly enriched and then continuously produced via chemostat operation of the bioreactor. When using a pH of 10 and about 0.2 M urea in a yeast extract-based medium, ureolytic bacteria developed under aerobic chemostat operation at hydraulic retention times of about 10 h with urease levels of about 60 μmol min⁻¹ ml⁻¹ culture. For cost minimization at an industrial scale the costly protein-rich yeast extract medium could be replaced by commercial milk powder or by lysed activated sludge. Glutamate, molasses, or glucose-based media did not result in the enrichment of ureolytic bacteria by the chemostat. The concentration of intracellular urease was sufficiently high such that the produced raw effluent from the reactor could be used directly for biocementation in the field.

  16. Characterization of biogas bibliography measures on sites; Caracterisation des Biogaz bibliographie mesures sur sites

    Energy Technology Data Exchange (ETDEWEB)

    Poulleau, J.

    2002-10-15

    The aim of this study is to define the pollutants emissions related to the combustion of biogas of different sources: motors, furnaces, flares...The project is presented in three parts: a bibliographic study on the chemical characterization of the biogas, a first series of measures on production sites and a second series of measures on a site of valorization and destruction of biogas. (A.L.B.)

  17. Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review.

    Science.gov (United States)

    Wang, Limei; Waltenberger, Birgit; Pferschy-Wenzig, Eva-Maria; Blunder, Martina; Liu, Xin; Malainer, Clemens; Blazevic, Tina; Schwaiger, Stefan; Rollinger, Judith M; Heiss, Elke H; Schuster, Daniela; Kopp, Brigitte; Bauer, Rudolf; Stuppner, Hermann; Dirsch, Verena M; Atanasov, Atanas G

    2014-11-01

    Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia associated with the metabolic syndrome and type 2 diabetes. In spite of being effective in normalization of blood glucose levels, the currently used PPARγ agonists from the thiazolidinedione type have serious side effects, making the discovery of novel ligands highly relevant. Natural products have proven historically to be a promising pool of structures for drug discovery, and a significant research effort has recently been undertaken to explore the PPARγ-activating potential of a wide range of natural products originating from traditionally used medicinal plants or dietary sources. The majority of identified compounds are selective PPARγ modulators (SPPARMs), transactivating the expression of PPARγ-dependent reporter genes as partial agonists. Those natural PPARγ ligands have different binding modes to the receptor in comparison to the full thiazolidinedione agonists, and on some occasions activate in addition PPARα (e.g. genistein, biochanin A, sargaquinoic acid, sargahydroquinoic acid, resveratrol, amorphastilbol) or the PPARγ-dimer partner retinoid X receptor (RXR; e.g. the neolignans magnolol and honokiol). A number of in vivo studies suggest that some of the natural product activators of PPARγ (e.g. honokiol, amorfrutin 1, amorfrutin B, amorphastilbol) improve metabolic parameters in diabetic animal models, partly with reduced side effects in comparison to full thiazolidinedione agonists. The bioactivity pattern as well as the dietary use of several of the identified active compounds and plant extracts warrants future research regarding their therapeutic potential and the possibility to modulate PPARγ activation by dietary interventions or food supplements. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  18. TRIM11 negatively regulates IFNβ production and antiviral activity by targeting TBK1.

    Directory of Open Access Journals (Sweden)

    Younglang Lee

    Full Text Available The innate immune response is a host defense mechanism against infection by viruses and bacteria. Type I interferons (IFNα/β play a crucial role in innate immunity. If not tightly regulated under normal conditions and during immune responses, IFN production can become aberrant, leading to inflammatory and autoimmune diseases. In this study, we identified TRIM11 (tripartite motif containing 11 as a novel negative regulator of IFNβ production. Ectopic expression of TRIM11 decreased IFNβ promoter activity induced by poly (I:C stimulation or overexpression of RIG-I (retinoic acid-inducible gene-I signaling cascade components RIG-IN (constitutively active form of RIG-I, MAVS (mitochondrial antiviral signaling protein, or TBK1 (TANK-binding kinase-1. Conversely, TRIM11 knockdown enhanced IFNβ promoter activity induced by these stimuli. Moreover, TRIM11 overexpression inhibited the phosphorylation and dimerization of IRF3 and expression of IFNβ mRNA. By contrast, TRIM11 knockdown increased the IRF3 phosphorylation and IFNβ mRNA expression. We also found that TRIM11 and TBK1, a key kinase that phosphorylates IRF3 in the RIG-I pathway, interacted with each other through CC and CC2 domain, respectively. This interaction was enhanced in the presence of the TBK1 adaptor proteins, NAP1 (NF-κB activating kinase-associated protein-1, SINTBAD (similar to NAP1 TBK1 adaptor or TANK (TRAF family member-associated NF-κB activator. Consistent with its inhibitory role in RIG-I-mediated IFNβ signaling, TRIM11 overexpression enhanced viral infectivity, whereas TRIM11 knockdown produced the opposite effect. Collectively, our results suggest that TRIM11 inhibits RIG-I-mediated IFNβ production by targeting the TBK1 signaling complex.

  19. Soil Moisture Active Passive Mission L4_C Data Product Assessment (Version 2 Validated Release)

    Science.gov (United States)

    Kimball, John S.; Jones, Lucas A.; Glassy, Joseph; Stavros, E. Natasha; Madani, Nima; Reichle, Rolf H.; Jackson, Thomas; Colliander, Andreas

    2016-01-01

    underlying FT and soil moisture constraints to these processes, 2) documenting primary connections between terrestrial water, energy and carbon cycles, and 3) improving understanding of terrestrial carbon sink activity in northern ecosystems. There are no L1 science requirements for the L4_C product; however self-imposed requirements have been established focusing on NEE as the primary product field for validation, and on demonstrating L4_C accuracy and success in meeting product science requirements (Jackson et al. 2012). The other L4_C product fields also have strong utility for carbon science applications; however, analysis of these other fields is considered secondary relative to primary validation activities focusing on NEE. The L4_C targeted accuracy requirements are to meet or exceed a mean unbiased accuracy (ubRMSE) for NEE of 1.6 g C/sq m/d or 30 g C/sq m/yr, emphasizing northern (45N) boreal and arctic ecosystems; this is similar to the estimated accuracy level of in situ tower eddy covariance measurement-based observations (Baldocchi 2008).

  20. Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts

    Science.gov (United States)

    Reich, K. M.; McAllister, T. N.; Gudi, S.; Frangos, J. A.

    1997-01-01

    Interstitial fluid flow may play a role in load-induced bone remodeling. Previously, we have shown that fluid flow stimulates osteoblast production of cAMP inositol trisphosphate (IP3), and PGE2. Flow-induced increases in cAMP and IP3 were shown to be a result of PG production. Thus, PGE2 production appears to be an important component in fluid flow induced signal transduction. In the present study, we investigated the mechanism of flow-induced PGE2 synthesis. Flow-induced a 20-fold increase in PGE2 production in osteoblasts. Increases were also observed with ALF4-(10mM) (98-fold), an activator of guanidine nucleotide-binding proteins (G proteins), and calcium ionophore A23187 (2 microM) (100-fold) in stationary cells. We then investigated whether flow stimulation is mediated by G proteins and increases in intracellular calcium. Flow-induced PGE2 production was inhibited by the G protein inhibitors GDP beta S (100 microM) and pertussis toxin (1 microgram/ml) by 83% and 72%, respectively. Chelation of extracellular calcium by EGTA (2 mM) and intracellular calcium by quin-2/AM (30 microM) blocked flow stimulation by 87% and 67%, respectively. These results suggest that G proteins and calcium play an important role in mediating mechanochemical signal transduction in osteoblasts.

  1. TWO ACTIVE STAGES OF AMBROSIA BEETLE, Platypus quercivorus MURAYAMA ESTIMATED FROM FRASS PRODUCTION

    Directory of Open Access Journals (Sweden)

    Hagus Tarno

    2012-10-01

    Full Text Available Beetle activity deep inside wood was studied in field (Mt. Yoshida, Kyoto and laboratory conditions by monitoring the type and amount of frass ejected from beetle galleries of Platypus quercivorus. Twenty-one galleries were selected from five infested Quercus serrata trees for field studies. In the laboratory, frass production was monitored for three galleries using a computer-aided electrical balance (A&D Co. Ltd.. Long-term patterns of frass production from field observation revealed that there are three distinguishable stages; a fibrous frass stage, an intermediate stage, and a powdery frass stage. The duration of the fibrous frass production was clearly different between galleries, ranging from five to twenty one days. The intermediate stage was also different from gallery to gallery, ranging from two to twenty days. Accordingly, the starting time of the third stage, powdery frass production, ranged from the 19th to the 27th day. Under laboratory conditions, the long-term patterns of frass production revealed that in galleries of logs no. 1 and 2 the fibrous frass period was stopped on the 23rd and 22nd day, respectively. Field monitoring revealed there was a negative relationship between the length of fibrous frass stage and the length of the intermediate stage.

  2. An efficient method to improve the production of methane from anaerobic digestion of waste activated sludge.

    Science.gov (United States)

    Li, Xiaolan; Xu, Xueqin; Huang, Shansong; Zhou, Yun; Jia, Haijiang

    2017-10-01

    Methane production from waste activated sludge (WAS) anaerobic digestion is always low due to slow hydrolysis rate and inappropriate ratio of carbon to nitrogen (C/N). In this work, a novel approach, i.e., co-digestion of WAS and tobacco waste (TW) using ozone pretreatment, to greatly enhance the production of methane is reported. Experimental results showed the optimal C/N and ozone dosage for methane production was 24:1 and 90 mg/g suspended solids, and the corresponding methane production was 203.6 mL/g volatile suspended solids, which was 1.3-fold that in mono-WAS digestion. Further investigation showed the co-digestion of WAS and TW was beneficial to the consumptions of protein and cellulose; also, the presence of ozone enhanced the disruption of organic substrates and production of short chain fatty acids, which provided sufficient digestion substrates for methane generation. Analysis of microbial community structure suggested that members of the phyla Bacteroidetes and Firmicutes were the dominant species when ozone pretreatment was applied. The findings obtained in this work might be of great importance for the treatment of WAS and TW.

  3. Productivity

    DEFF Research Database (Denmark)

    Spring, Martin; Johnes, Geraint; Hald, Kim Sundtoft

    Productivity is increasingly critical for developed economies. It has always been important: as Paul Krugman puts it, “Productivity isn’t everything, but in the long run it is almost everything. A country’s ability to improve its standard of living over time depends almost entirely on its ability...... to raise its output per worker”(Krugman, 1994). Analyses of productivity have, by and large, been the preserve of economists. Operations Management (OM) is rooted in a similar concern for the efficient use of scarce resources; Management Accounting (MA) is concerned with the institutionalised measurement...... and management of productivity. Yet the three perspectives are rarely connected. This paper is a sketch of a literature review seeking to identify, contrast and reconcile these three perspectives. In so doing, it aims to strengthen the connections between policy and managerial analyses of productivity....

  4. Mesurements of intracellular ATP provide new insight into the regulation of glycolysis in the yeast Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Ytting, Cecilie Karkov; Fuglsang, Anja Thoe; Hiltunen, J. Kalervo

    2012-01-01

    Glycolysis in the yeast Saccharomyces cerevisiae exhibits temporal oscillation under anaerobic or semianaerobic conditions. Previous evidence indicated that at least two membrane-bound ATPases, the mitochondrial F0F1 ATPase and the plasma membrane P-type ATPase (Pma1p), were important in regulating...... of the temporal behaviour of intracellular ATP in a yeast strain with oscillating glycolysis showed that, in addition to oscillation in intracellular ATP, there is an overall slow decrease in intracellular ATP because the ATP consumption rate exceeds the ATP production in glycolysis. Measurements of the temporal...... activity is under strict control. In the absence of glucose ATPase activity is switched off, and the intracellular ATP concentration is high. When glucose is added to the cells the ATP concentration starts to decrease, because ATP consumption exceeds ATP production by glycolysis. Finally, when glucose...

  5. 77 FR 65360 - Foreign-Trade Zone 168-Dallas/Ft. Worth, TX; Notification of Proposed Production Activity...

    Science.gov (United States)

    2012-10-26

    ... Production Activity, Richemont North America, Inc. dba Cartier (Eyewear Assembly/Kitting), Grand Prairie, TX... notification of proposed production activity on behalf of Richemont North America, Inc. dba Cartier (Cartier..., Washington, DC 20230-0002, and in the ``Reading Room'' section of the Board's Web site, which is accessible...

  6. 77 FR 28569 - Foreign-Trade Zone 92-Gulfport, MS Notification of Proposed Production Activity; Gulf Ship, LLC...

    Science.gov (United States)

    2012-05-15

    ... Foreign-Trade Zones Board Foreign-Trade Zone 92--Gulfport, MS Notification of Proposed Production Activity... FTZ 92, submitted a notification of proposed production activity on behalf of Gulf Ship, LLC (Gulf... Commerce, 1401 Constitution Avenue NW., Washington, DC 20230-0002, and in the ``Reading Room'' section of...

  7. 77 FR 65856 - Foreign-Trade Subzone 93G-Oxford, NC; Notification of Proposed Production Activity Revlon...

    Science.gov (United States)

    2012-10-31

    ... Activity Revlon Consumer Products Corporation (Cosmetics and Personal Care Products) Revlon Consumer... activity for its facility in Oxford, North Carolina. The notification conforming to the requirements of the...., Washington, DC 20230-0002, and in the ``Reading Room'' section of the Board's Web site, which is accessible...

  8. 77 FR 73415 - Authorization of Export Production Activity, Foreign-Trade Subzone 12A, TST NA Trim, LLC (Fabric...

    Science.gov (United States)

    2012-12-10

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-62-2012] Authorization of Export Production Activity, Foreign-Trade Subzone 12A, TST NA Trim, LLC (Fabric/Leather Lamination and Cutting), Hidalgo, TX... of proposed production activity to the Foreign-Trade Zones (FTZ) Board on behalf of TST NA Trim, LLC...

  9. 78 FR 56859 - Foreign-Trade Zone 267-Fargo, North Dakota; Authorization of Production Activity; CNH America...

    Science.gov (United States)

    2013-09-16

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-51-2013] Foreign-Trade Zone 267--Fargo, North Dakota; Authorization of Production Activity; CNH America, LLC, (Construction and Agricultural Equipment..., submitted a notification of proposed production activity to the Foreign-Trade Zones (FTZ) Board on behalf of...

  10. 78 FR 68814 - Subzone 114F, Authorization of Production Activity, Easton-Bell Sports, Inc., (Sports Equipment...

    Science.gov (United States)

    2013-11-15

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-74-2013] Subzone 114F, Authorization of Production Activity, Easton-Bell Sports, Inc., (Sports Equipment), Rantoul, Illinois On June 27, 2013, Easton-Bell Sports, Inc. submitted a notification of proposed production activity to the Foreign-Trade Zones...

  11. 78 FR 59650 - Subzone 9F, Authorization of Production Activity, The Gas Company, LLC dba Hawai'i Gas...

    Science.gov (United States)

    2013-09-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-53-2013] Subzone 9F, Authorization of Production Activity, The Gas Company, LLC dba Hawai'i Gas, (Synthetic Natural Gas), Kapolei, Hawaii On May 22, 2013, The Gas Company, LLC dba Hawai'i Gas submitted a notification of proposed production activity to...

  12. beta. -endorphin augments the cytolytic activity and interferon production of natural killer cells

    Energy Technology Data Exchange (ETDEWEB)

    Mandler, R.N.; Biddison, W.E.; Mandler, R.; Serrate, S.A.

    1986-02-01

    The in vitro effects of the neurohormone ..beta..-endorphin (b-end) on natural killer (NK) activity and interferon (IFN) production mediated by large granular lymphocytes (LGL) were investigated. LGL-enriched fractions from peripheral blood mononuclear cells (PBMC) from normal human volunteers were obtained by fractionation over discontinuous Percoll gradients. LGL were preincubated with or without various concentrations of b-end or the closely related peptides ..cap alpha..-endorphin (a-end), ..gamma..-endorphin (g-end), or D-ALA/sub 2/-..beta..-endorphin (D-ALA/sub 2/-b-end), a synthetic b-end analogue. NK activity was assayed on /sup 51/Cr-labeled K562 target cells. Preincubation of LGL effectors (but not K562 targets) for 2 to 18 hr with concentrations of b-end between 10/sup -7/ M and 10/sup -10/ M produced significant augmentation of NK cytolytic activity (mean percentage increase: 63%). The classic opiate antagonist naloxone blocked the enhancing effect when used at a 100-fold molar excess relative to b-end. These findings demonstrate that b-end enhances NK activity and IFN production of purified LGL, and suggests that b-end might bind to an opioid receptor on LGL that can be blocked by naloxone. These results lend support to the concepts of regulation of the immune response by neurohormones and the functional relationship between the nervous and immune systems.

  13. Antiadherent and Antibiofilm Activity of Humulus lupulus L. Derived Products: New Pharmacological Properties

    Directory of Open Access Journals (Sweden)

    Marcin Rozalski

    2013-01-01

    Full Text Available New antimicrobial properties of products derived from Humulus lupulus L. such as antiadherent and antibiofilm activities were evaluated. The growth of gram-positive but not gram-negative bacteria was inhibited to different extents by these compounds. An extract of hop cones containing 51% xanthohumol was slightly less active against S. aureus strains (MIC range 31.2–125.0 μg/mL than pure xanthohumol (MIC range 15.6–62.5 μg/mL. The spent hop extract, free of xanthohumol, exhibited lower but still relevant activity (MIC range 1-2 mg/mL. There were positive coactions of hop cone, spent hop extracts, and xanthohumol with oxacillin against MSSA and with linezolid against MSSA and MRSA. Plant compounds in the culture medium at sub-MIC concentrations decreased the adhesion of Staphylococci to abiotic surfaces, which in turn caused inhibition of biofilm formation. The rate of mature biofilm eradication by these products was significant. The spent hop extract at MIC reduced biofilm viability by 42.8%, the hop cone extract by 74.8%, and pure xanthohumol by 86.5%. When the hop cone extract or xanthohumol concentration was increased, almost complete biofilm eradication was achieved (97–99%. This study reveals the potent antibiofilm activity of hop-derived compounds for the first time.

  14. STABILIZATION OF ACTIVE SLUDGE AFTER WASTEWATER TREATMENT CONTAMINATED BY PETROLEUM PRODUCTS

    Directory of Open Access Journals (Sweden)

    Olena Semenova

    2016-06-01

    Full Text Available Purpose: Biochemical purification of wastewater containing refined petroleum products takes place due to the oxidation of pollutants by active sludge organisms. As a result of this process the intense consumption of pollutants by active sludge and its growth occurs. Therefore, the possibility to use active sludge containing refined petroleum products after wastewater treatment requires its stabilization. Methods: In this work the oxidation by a 30% hydrogen peroxide solution was studied for its use as a stabilizer. Chemical oxidizers, including hydrogen peroxide destroy organic polymers retaining free water thus promoting water release from the structure of sludge particles. On the other hand remains of fine structured oxidized biopolymers can lead to filter clogging, that is, reduce moisture exchange of sludge. Results: The experiment was carried out to find out the correlation between the doses of hydrogen peroxide and the resistivity value of sludge filtration. Discussion: Stabilized active sludge can be used as a fuel for boiler rooms, which in its turn will reduce natural gas consumption for the enterprise needs.

  15. Potassium humate inhibits complement activation and the production of inflammatory cytokines in vitro

    Energy Technology Data Exchange (ETDEWEB)

    van Rensburg, C.E.J.; Naude, P.J. [University of Pretoria, Pretoria (South Africa)

    2009-08-15

    The effects of brown coal derived potassium humate on lymphocyte proliferation, cytokine production and complement activation were investigated in vitro. Potassium humate increased lymphocyte proliferation of phytohaemaglutinin A (PHA) and pokeweed mitogen (PWM) stimulated mononuclear lymphocytes (MNL) in vitro from concentrations of 20 to 80 {mu} g/ml, in a dose dependant manner. On the other hand potassium humate, at 40 {mu} g/ml, significantly inhibited the release of TNF-alpha, IL-1 beta, IL-6 and IL-10 by PHA stimulated MNL. Regarding complement activation it was found that potassium humate inhibits the activation of both the alternative and classical pathways without affecting the stability of the red blood cell membranes. These results indicate that the anti-inflammatory potential of potassium humate could be partially due to the inhibition of pro-inflammatory cytokines responsible for the initiation of these reactions as well as inhibition of complement activation. The increased lymphocyte proliferation observed, might be due to increased IL-2 production as previously been documented.

  16. Activation of macrophages by silicones: phenotype and production of oxidant metabolites

    Directory of Open Access Journals (Sweden)

    Sodero Natalia

    2002-07-01

    Full Text Available Abstract Background The effect of silicones on the immune function is not fully characterized. In clinical and experimental studies, immune alterations associated with silicone gel seem to be related to macrophage activation. In this work we examined in vivo, phenotypic and functional changes on peritoneal macrophages early (24 h or 48 h and late (45 days after the intraperitoneal (i.p. injection of dimethylpolysiloxane (DMPS (silicone. We studied the expression of adhesion and co-stimulatory molecules and both the spontaneous and the stimulated production of reactive oxygen intermediates and nitric oxide (NO. Results The results presented here demonstrate that the fluid compound DMPS induced a persistent cell recruitment at the site of the injection. Besides, cell activation was still evident 45 days after the silicone injection: activated macrophages exhibited an increased expression of adhesion (CD54 and CD44 and co-stimulatory molecules (CD86 and an enhanced production of oxidant metabolites and NO. Conclusions Silicones induced a persistent recruitment of leukocytes at the site of the injection and macrophage activation was still evident 45 days after the injection.

  17. Modeling effects of DO and SRT on activated sludge decay and production.

    Science.gov (United States)

    Liu, Guoqiang; Wang, Jianmin

    2015-09-01

    The effect of dissolved oxygen (DO) on the endogenous decay of active heterotrophic biomass and the hydrolysis of cell debris were studied. With the inclusion of a hydrolysis process for the cell debris, mathematical models that are capable of quantifying the effects of DO and sludge retention time (SRT) on concentrations of active biomass and cell debris in activated sludge are presented. By modeling the biomass cultivated with unlimited DO, the values of endogenous decay coefficient for heterotrophic biomass, the hydrolysis constant of cell debris, and the fraction of decayed biomass that became cell debris were determined to be 0.38 d(-1), 0.013 d(-1), and 0.28, respectively. Results from modeling the biomass cultivated under different DO conditions suggested that the experimental low DO (∼0.2 mg/L) did not inhibit the endogenous decay of heterotrophic biomass, but significantly inhibited the hydrolysis of cell debris with a half-velocity constant value of 2.1 mg/L. Therefore, the increase in sludge production with low DO was mainly contributed by cell debris rather than the active heterotrophic biomass. Maximizing sludge production during aerobic wastewater treatment could reduce aeration energy consumption and improve biogas energy recovery potential. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Monthly results of measurements: January 1995; Tableaux mensuels des mesures. Janvier 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: Mars 2000; Tableaux mensuels des mesures. Mars 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  20. Monthly results of measurements: Aug 1997; Tableaux mensuels des mesures. Aout 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  1. Monthly results of measurements: Dec 1996; Tableaux mensuels des mesures. Decembre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  2. Monthly results of measurements: October 1994; Tableaux mensuels des mesures. Octobre 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  3. Monthly results of measurements: December 1997; Tableaux mensuels des mesures. Decembre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  4. Monthly results of measurements: July 1997; Tableaux mensuels des mesures. Juillet 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  5. Monthly results of measurements: Feb 1997; Tableaux mensuels des mesures. Fevrier 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  6. Monthly results of measurements: May 1997; Tableaux mensuels des mesures. Mai 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  7. Monthly results of measurements: Jan 1997; Tableaux mensuels des mesures. Janvier 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  8. Monthly results of measurements: Jun 1997; Tableaux mensuels des mesures. Juin 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  9. Monthly results of measurements: November 1998; Tableaux mensuels des mesures. Novembre 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  10. Monthly results of measurements. Apr 1999; Tableaux mensuels des mesures. Avril 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  11. Monthly results of measurements: Feb 2000; Tableaux mensuels des mesures. Fevrier 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  12. Monthly results of measurements: Jan 2001; Tableaux mensuels des mesures. Janvier 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  13. Monthly results of measurements: Apr 2001; Tableaux mensuels des mesures. Avril 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  14. Monthly results of measurements: Jan 2000; Tableaux mensuels des mesures. Janvier 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  15. Monthly results of measurements: Dec 2000; Tableaux mensuels des mesures. Decembre 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  16. Monthly results of measurements: Mar 2001; Tableaux mensuels des mesures. Mars 2001

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  17. Monthly results of measurements: April 2000; Tableaux mensuels des mesures. Avril 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: October 1996; Tableaux mensuels des mesures. Octobre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  19. Monthly results of measurements: March 1996; Tableaux mensuels des mesures. Mars 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  20. Monthly results of measurements: February 1995; Tableaux mensuels des mesures. Fevrier 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  1. Monthly results of measurements: December 1994; Tableaux mensuels des mesures. Decembre 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  2. Monthly results of measurements: March 1997; Tableaux mensuels des mesures. Mars 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  3. Monthly results of measurements: July 1995; Tableaux mensuels des mesures. Juillet 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  4. Monthly results of measurements: July 1999; Tableaux mensuels des mesures. Juillet 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  5. Monthly results of measurements: Aug 2000; Tableaux mensuels des mesures. Aout 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  6. Monthly results of measurements. Mar 1999; Tableaux mensuels des mesures. Mars 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    his report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  7. Monthly results of measurements: Oct 1999; Tableaux mensuels des mesures. Octobre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain(milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  8. Monthly results of measurements: January 1998; Tableaux mensuels des mesures. Janvier 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  9. Monthly results of measurements: May 1998; Tableaux mensuels des mesures. Mai 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  10. Monthly results of measurements: Sep 1996; Tableaux mensuels des mesures. Septembre 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  11. Monthly results of measurements. Jun 1996; Tableaux mensuels des mesures. Juin 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  12. Monthly results of measurements. May 1996; Tableaux mensuels des mesures. Mai 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  13. Monthly results of measurements: February 1996; Tableaux mensuels des mesures. Fevrier 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  14. Monthly results of measurements: Dec 1999; Tableaux mensuels des mesures. Decembre 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  15. Monthly results of measurements: Aug 1999; Tableaux mensuels des mesures. Aout 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    his report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  16. Monthly results of measurements: November 1997; Tableaux mensuels des mesures. Novembre 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables

  17. Monthly results of measurements: May 2000; Tableaux mensuels des mesures. Mai 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.

  18. Monthly results of measurements: Jul 1998; Tableaux mensuels des mesures. Juillet 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  19. Monthly tables of measurements. October 2000; Tableaux mensuels des mesures. Octobre 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-10-01

    This report of the O.P.R.I. (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables. (N.C.)

  20. Monthly results of measurements: January 1999; Tableaux mensuels des mesures. Janvier 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    This report of the OPRI (Office of Protection against Ionizing Radiations) exposes the principal results concerning the routine monitoring of environmental radioactivity in France: atmospheric dusts, rainwater, surface water, underground water, sewage water, drinking water, food chain (milk, vegetables, fishes), sea water around nuclear sites and other sites. The activities of various radioisotopes are presented in tables.