Sample records for activation effects mitigated

  1. Evaluating the effectiveness of road mitigation measures

    NARCIS (Netherlands)

    Grift, van der E.A.; Ree, van R.; Fahrig, L.; Houlahan, J.E.; Jaeger, J.A.G.; Klar, N.; Francisco Madriñan, L.; Olson, L.


    The last 20 years have seen a dramatic increase in efforts to mitigate the negative effects of roads and traffic on wildlife, including fencing to prevent wildlife-vehicle collisions and wildlife crossing structures to facilitate landscape connectivity. While not necessarily explicitly articulated,

  2. Harmonics Mitigation Using Active Power Filter

    Directory of Open Access Journals (Sweden)

    Sourabh Gupta


    Full Text Available This paper is proposed to reconsider the development of active power filter (APF technologies that are routinely utilized to mitigate harmonics in utility power lines. This reconsider can furthermore be considered as a “tutorial-type paper” as it provides a holistic coverage of the APF technologies by omitting the tedious details, but without losing the major essence of the subject matter. It is wanted that by this approach, it would be likely to lure more power engineering readers to be involved in this important and growing area. The discussion starts with a short overview of harmonic distortion difficulties and their impacts on electric power and powered value. The operation of common APF topologies, namely the shunt, sequence and hybrid APFs are recounted in minutia. This is followed by a reconsider on different types of reference pointer estimation extraction methods. In specific, the application of the p-q and elongation p-q theorems to extract the quotation pointers are elaborated, as they are the most commonly discovered in practical APF systems eventually, an overview of the APF command schemes is provided. A short consideration on the APF-solar photovoltaic scheme is furthermore granted. At the end of the paper, important references are cited to aid readers who are interested to discover the subject in larger detail.

  3. Mitigation of the effects of sulphur pollution

    Energy Technology Data Exchange (ETDEWEB)

    Chang, B.; Wilson, R.


    As an introduction to the discussion of mitigation of the effects of SO/sub 2/, its health effect on man and the use of sulfates as indicators of the health hazard are first considered. The use of tall chimney stacks and intermittent control and other schemes to reduce the SO/sub 2/ release to the atmosphere are discussed. The problems of administration and forecasting are analyzed and legal problems associated with SO/sub 2/ control are reviewed. In an appendix an analysis of federal jurisdiction over interstate pollution and possible avenues of litigation open to the states is presented. (JSR)

  4. Addition of polyaluminiumchloride (PACl) to waste activated sludge to mitigate the negative effects of its sticky phase in dewatering-drying operations. (United States)

    Peeters, Bart; Dewil, Raf; Vernimmen, Luc; Van den Bogaert, Benno; Smets, Ilse Y


    This paper presents a new application of polyaluminiumchloride (PACl) as a conditioner for waste activated sludge prior its dewatering and drying. It is demonstrated at lab scale with a shear test-based protocol that a dose ranging from 50 to 150 g PACl/kg MLSS (mixed liquor suspended solids) mitigates the stickiness of partially dried sludge with a dry solids content between 25 and 60 %DS (dry solids). E.g., at a solids dryness of 46% DS the shear stress required to have the pre-consolidated sludge slip over a steel surface is reduced with 35%. The salient feature of PACl is further supported by torque data from a full scale decanter centrifuge used to dewater waste sludge. The maximal torque developed by the screw conveyor inside the decanter centrifuge is substantially reduced with 20% in the case the sludge feed is conditioned with PACl. The beneficial effect of waste sludge conditioning with PACl is proposed to be the result of the bound water associated with the aluminium polymers in PACl solutions which act as a type of lubrication for the intrinsically sticky sludge solids during the course of drying. It can be anticipated that PACl addition to waste sludge will become a technically feasible and very effective method to avoid worldwide fouling problems in direct sludge dryers, and to reduce torque issues in indirect sludge dryers as well as in sludge decanter centrifuges.

  5. Waste Management Policy Framework to Mitigate Terrorist Intrusion Activities

    Energy Technology Data Exchange (ETDEWEB)

    Redus, Kenneth, S.


    A policy-directed framework is developed to support US Department of Energy (DOE) counterterrorism efforts, specifically terrorist intrusion activities that affect of Environmental Management (EM) programs. The framework is called the Security Effectiveness and Resource Allocation Definition Forecasting and Control System (SERAD-FACS). Use of SERAD-FACS allows trade-offs between resources, technologies, risk, and Research and Development (R&D) efforts to mitigate such intrusion attempts. Core to SERAD-FACS is (1) the understanding the perspectives and time horizons of key decisionmakers and organizations, (2) a determination of site vulnerabilities and accessibilities, and (3) quantifying the measures that describe the risk associated with a compromise of EM assets. The innovative utility of SERAD-FACS is illustrated for three integrated waste management and security strategies. EM program risks, time delays, and security for effectiveness are examined to demonstrate the significant cost and schedule impact terrorist activities can have on cleanup efforts in the DOE complex.

  6. Best Mitigation Paths To Effectively Reduce Earth's Orbital Debris (United States)

    Wiegman, Bruce M.


    This slide presentation reviews some ways to reduce the problem posed by debris in orbit around the Earth. It reviews the orbital debris environment, the near-term needs to minimize the Kessler syndrome, also known as collisional cascading, a survey of active orbital debris mitigation strategies, the best paths to actively remove orbital debris, and technologies that are required for active debris mitigation.

  7. Mitigating reptile road mortality: fence failures compromise ecopassage effectiveness.

    Directory of Open Access Journals (Sweden)

    James H Baxter-Gilbert

    Full Text Available Roadways pose serious threats to animal populations. The installation of roadway mitigation measures is becoming increasingly common, yet studies that rigorously evaluate the effectiveness of these conservation tools remain rare. A highway expansion project in Ontario, Canada included exclusion fencing and ecopassages as mitigation measures designed to offset detrimental effects to one of the most imperial groups of vertebrates, reptiles. Taking a multispecies approach, we used a Before-After-Control-Impact study design to compare reptile abundance on the highway before and after mitigation at an Impact site and a Control site from 1 May to 31 August in 2012 and 2013. During this time, radio telemetry, wildlife cameras, and an automated PIT-tag reading system were used to monitor reptile movements and use of ecopassages. Additionally, a willingness to utilize experiment was conducted to quantify turtle behavioral responses to ecopassages. We found no difference in abundance of turtles on the road between the un-mitigated and mitigated highways, and an increase in the percentage of both snakes and turtles detected dead on the road post-mitigation, suggesting that the fencing was not effective. Although ecopassages were used by reptiles, the number of crossings through ecopassages was lower than road-surface crossings. Furthermore, turtle willingness to use ecopassages was lower than that reported in previous arena studies, suggesting that effectiveness of ecopassages may be compromised when alternative crossing options are available (e.g., through holes in exclusion structures. Our rigorous evaluation of reptile roadway mitigation demonstrated that when exclusion structures fail, the effectiveness of population connectivity structures is compromised. Our project emphasizes the need to design mitigation measures with the biology and behavior of the target species in mind, to implement mitigation designs in a rigorous fashion, and quantitatively

  8. Interharmonic mitigation of adjustable speed drives using an active DC-link capacitor

    DEFF Research Database (Denmark)

    Soltani, Hamid; Loh, Poh Chiang; Blaabjerg, Frede;


    operating frequency. As there is a growing discussion about the interharmonic effects on the grid and its limitation, the reduction and mitigation of these components is worthwhile especially when more drives are tied to the grid. This paper proposes a new dc-link active capacitor in order to reduce...

  9. Efficiency of parks in mitigating urban heat island effect

    DEFF Research Database (Denmark)

    Feyisa, Gudina Legese; Dons, Klaus; Meilby, Henrik


    Urban green infrastructure can to a certain extent mitigate urban warming. However, the cooling effect of plants varies with space, time and plant-specific properties. To contribute to our understanding of the cooling effect of vegetation on urban surface and air temperature, 21 parks in Addis...

  10. Mitigation of TNT and Destex explosion effects using water mist. (United States)

    Willauer, Heather D; Ananth, Ramagopal; Farley, John P; Williams, Frederick W


    The effects water mist has on the overpressures produced by the detonation of 50 lb equivalent of high explosives (HE) TNT and Destex in a chamber is reported. The overpressures for each charge density were measured with and without mist preemptively sprayed into the space. A droplet analyzer was placed in the chamber prior to the detonation experiments to characterize the water mist used to mitigate the explosion overpressures. The impulse, initial blast wave, and quasi-static overpressure measured in the blast mitigation experiments were reduced by as much as 40%, 36%, 35% for TNT and 43%, 25%, 33% for Destex when water mist was sprayed 60s prior to detonation at a concentration of 70 g/m(3) and droplet Sauter Mean Diameter (SMD) 54 microm. These results suggest that current water mist technology is a potentially promising concept for the mitigation of overpressure effects produced from the detonation of high explosives.

  11. Mitigating the Harmful Effects of Violent Television (United States)

    Rosenkoetter, Lawrence I.; Rosenkoetter, Sharon E.; Ozretich, Rachel A.; Acock, Alan C.


    In an effort to minimize the harmful effects of violent TV, a yearlong intervention was undertaken with children in Grades 1 through 3 (N = 177). The classroom-based intervention consisted of 31 brief lessons that emphasized the many ways in which television distorts violence. As hypothesized, the intervention resulted in a reduction in children's…

  12. Systematic effects in radon mitigation by sump/pump remediation

    Energy Technology Data Exchange (ETDEWEB)

    Groves-Kirkby, C.J.; Denman, A.R. [Northampton General Hospital, Medical Physics Dept. (United Kingdom); Groves-Kirkby, C.J.; Woolridge, A.C. [Northampton Univ., School of Health (United Kingdom); Woolridge, A.C.; Phillips, P.S.; Crockett, R.G.M. [Northampton Univ., School of Applied Sciences (United Kingdom); Tornberg, R. [Radon Centres Ltd., Grove Farm, Moulton, Northampton (United Kingdom)


    Sump/Pump remediation is widely used in the United Kingdom to mitigate indoor radon gas levels in residential properties. To quantify the effectiveness of this technology, a study was made of radon concentration data from a set of 173 homes situated in radon Affected Areas in and around Northamptonshire, U.K., re-mediated using conventional sump/pump tology. This approach is characterised by a high incidence of satisfactory mitigation outcomes, with more than 75% of the sample exhibiting mitigation factors (defined as the ratio of radon concentrations following and prior to remediation) of 0.2 or better. There is evidence of a systematic trend, where houses with higher initial radon concentrations have higher mitigation factors, suggesting that the total indoor radon concentration within a dwelling can be represented by two components, one susceptible to mitigation by sump/pump remediation, the other remaining essentially unaffected by these remediation strategies. The first component can be identified with ground-radon emanating from the subsoil and bedrock geologies, percolating through the foundations of the dwelling as a component of the soil-gas, potentially capable of being attenuated by sump/pump or radon-barrier remediation. The second contribution is attributed to radon emanating from materials used in the construction of the dwelling, principally concrete and gypsum plaster-board, with a further small contribution from the natural background level, and is essentially unaffected by ground-level remediation strategies. Modelling of such a two-component radon dependency using realistic ground-radon attenuation factors in conjunction with typical structural-radon levels yields behaviour in good agreement with the observed inverse-power dependence of mitigation factor on initial radon concentration. (authors)

  13. Exploring the Effect of Phyllanthus emblica L. on Cognitive Performance, Brain Antioxidant Markers and Acetylcholinesterase Activity in Rats: Promising Natural Gift for the Mitigation of Alzheimer's Disease (United States)

    Uddin, Md. Sahab; Mamun, Abdullah Al; Hossain, Md. Sarwar; Akter, Farjana; Iqbal, Mohammed Ashraful; Asaduzzaman, Md.


    Neurodegenerative diseases are incurable and debilitating conditions that result in the progressive degeneration of nerve cells, which affect the cognitive activity. Currently, as a result of multiple studies linking Alzheimer's disease (AD) to oxidative damage, the uses of natural antioxidant to prevent, delay, or enhance the pathological changes underlying the progression of AD has received considerable attention. Therefore, this study was aimed at examining the effect of ethanolic extracts of Phyllanthus emblica (EEPE) ripe (EEPEr) and EEPE unripe (EEPEu) fruits on cognitive functions, brain antioxidant enzymes, and acetylcholinesterase (AChE) activity in rat. The effects of EEPEr and EEPEu fruits (i.e., 100 and 200 mg/kg b.w.) were examined in Swiss albino male rats for 12 days and its effect on cognitive functions, brain antioxidant enzymes, and AChE activity determined. Learning and memory enhancing activity of EEPE fruit was examined by using passive avoidance test and rewarded alternation test. Antioxidant potentiality was evaluated by measuring the activity of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase, reduced glutathione (GSH), glutathione-S-transferase, and the contents of thiobarbituric acid reactive substances (TBARS) in entire brain tissue homogenates. AChE activity was determined using colorimetric method. Administration of the highest dose (i.e., 200 mg/kg b.w.) of EEPEr fruit significantly (p < 0.01) and both lowest and highest doses (i.e., 100 and 200 mg/kg b.w.) of EEPEu fruit markedly (p < 0.05, p < 0.001) increased step-through latency in rats on 6th, 11th, and 12th day with respect to the control group. For aforementioned doses, the percentage of memory retention (MR) was considerably (p < 0.05, p < 0.01) increased in rats on 10th, 11th, and 12th days with respect to the control group. The extract, particularly highest dose (i.e., 200 mg/kg b.w.) of EEPEr

  14. Mitigation of Wind Power Fluctuation by Active Current Control of Variable Speed Wind Turbines

    DEFF Research Database (Denmark)

    Zhang, Yunqian; Chen, Zhe; Hu, Weihao;


    Wind shear and tower shadow are the sources of power fluctuation of grid connected wind turbines during continuous operation. This paper presents a simulation model of a MW-level doubly fed induction generator (DFIG) based variable speed wind turbine with a partial-scale back-to-back power...... converter in Simulink. A simple and effective method of wind power fluctuations mitigation by active current control of DFIG is proposed. It smoothes the generator output active power oscillations by adjusting the active current of the DFIG, such that the power oscillation is stored as the kinetic energy...

  15. Technostress:negative effect on performance and possible mitigations


    Tarafdar, Monideepa; Pullins, Ellen; Ragu-Nathan, T. S


    We investigate the effect of conditions that create technostress, on technology-enabled innovation, technology-enabled performance and overall performance. We further look at the role of technology self-efficacy, organizational mechanisms that inhibit technostress and technology competence as possible mitigations to the effects of technostress creators. Our findings show a negative association between technostress creators and performance. We find that, while traditional effort-based mechanis...

  16. Mitigation of indirect environmental effects of GM crops. (United States)

    Pidgeon, J D; May, M J; Perry, J N; Poppy, G M


    Currently, the UK has no procedure for the approval of novel agricultural practices that is based on environmental risk management principles. Here, we make a first application of the 'bow-tie' risk management approach in agriculture, for assessment of land use changes, in a case study of the introduction of genetically modified herbicide tolerant (GMHT) sugar beet. There are agronomic and economic benefits, but indirect environmental harm from increased weed control is a hazard. The Farm Scale Evaluation (FSE) trials demonstrated reduced broad-leaved weed biomass and seed production at the field scale. The simplest mitigation measure is to leave a proportion of rows unsprayed in each GMHT crop field. Our calculations, based on FSE data, show that a maximum of 2% of field area left unsprayed is required to mitigate weed seed production and 4% to mitigate weed biomass production. Tilled margin effects could simply be mitigated by increasing the margin width from 0.5 to 1.5 m. Such changes are cheap and simple to implement in farming practices. This case study demonstrates the usefulness of the bow-tie risk management approach and the transparency with which hazards can be addressed. If adopted generally, it would help to enable agriculture to adopt new practices with due environmental precaution.

  17. Co-active receptor tyrosine kinases mitigate the effect of FGFR inhibitors in FGFR1-amplified lung cancers with low FGFR1 protein expression. (United States)

    Kotani, H; Ebi, H; Kitai, H; Nanjo, S; Kita, K; Huynh, T G; Ooi, A; Faber, A C; Mino-Kenudson, M; Yano, S


    Targeted therapies are effective in subsets of lung cancers with EGFR mutations and anaplastic lymphoma kinase (ALK) translocations. Large-scale genomics have recently expanded the lung cancer landscape with FGFR1 amplification found in 10-20% of squamous cell carcinomas (SCCs). However, the response rates have been low for biomarker-directed fibroblast growth factor receptor (FGFR) inhibitor therapy in SCC, which contrasts to the relatively high rates of response seen in EGFR mutant and ALK-translocated lung cancers treated with epidermal growth factor receptor (EGFR) inhibitors and ALK inhibitors, respectively. In order to better understand the low response rates of FGFR1-amplified lung cancers to FGFR inhibitors, relationships between gene copy number, mRNA expression and protein expression of FGFR1 were assessed in cell lines, tumor specimens and data from The Cancer Genome Atlas. The importance of these factors for the sensitivity to FGFR inhibitors was determined by analyzing drug screen data and conducting in vitro and in vivo experiments. We report that there was a discrepancy between FGFR1 amplification level and FGFR1 protein expression in a number of these cell lines, and the cancers with unexpectedly low FGFR1 expression were uniformly resistant to the different FGFR inhibitors. Further interrogation of the receptor tyrosine kinase activity in these discordant cell lines revealed co-activation of HER2 and platelet-derived growth factor receptor-α (PDGFRα) caused by gene amplification or ligand overexpression maintained phosphoinositide 3-kinase (PI3K) and MEK/ERK signaling even in the presence of FGFR inhibitor. Accordingly, co-inhibition of FGFR1 and HER2 or PDGFRα led to enhanced drug responses. In contrast, FGFR1-amplified high FGFR1 protein-expressing lung cancers are sensitive to FGFR inhibitor monotherapy by downregulating ERK signaling. Addition of a PI3K inhibitor to these high FGFR1 protein-expressing cancers further sensitized them to FGFR

  18. Cost effectiveness of GHG mitigation options and policy implication

    Energy Technology Data Exchange (ETDEWEB)

    Lim, K. S. [Korea Institute for Industrial Economics and Trade, Seoul (Korea, Republic of)


    This paper represents the summary findings and conclusions of several studies implemented about microeconomics and macroeconomics marginal costs of GHG abatement policies. Financial, economic, and, where possible, environmental microeconomics costs of reducing GHGs are estimated by a World Bank team. Six energy-related CO{sub 2} mitigation policy options are applied to estimate the macroeconomics costs of GHG emission reduction, the macroeconomics impacts on the Chinese economy. In terms of policy, conservation is a better option to cope with a restrictive mitigation constraint, assuming a developing country can achieve planned energy-saving targets. Without a CO{sub 2} emission constraint or with less restrictive CO{sub 2} emission constraints, however, the simulation results indicate that a conservation strategy may be less attractive than fuel substitution in a developing country, mainly due to the economic dampening effect of reduced production in the energy sectors. This finding suggests that an often-cited costless or negative-cost energy conservation policy may not be a better option when a less restrictive mitigation target is in force. This does not mean that the potential for energy efficiency improvements in a developing country is not worthwhile, but that the overall macroeconomics impacts should be considered before implementing the policy option. (author). 9 refs., 3 figs., 3 tabs.

  19. Mitigating the Urban Heat Island Effect in Megacity Tehran

    Directory of Open Access Journals (Sweden)

    Sahar Sodoudi


    Full Text Available Cities demonstrate higher nocturnal temperatures than surrounding rural areas, which is called “urban heat island” (UHI effect. Climate change projections also indicate increase in the frequency and intensity of heat waves, which will intensify the UHI effect. As megacity Tehran is affected by severe heatwaves in summer, this study investigates its UHI characteristics and suggests some feasible mitigation strategies in order to reduce the air temperature and save energy. Temperature monitoring in Tehran shows clear evidence of the occurrence of the UHI effect, with a peak in July, where the urban area is circa 6 K warmer than the surrounding areas. The mobile measurements show a park cool island of 6-7 K in 2 central parks, which is also confirmed by satellite images. The effectiveness of three UHI mitigation strategies high albedo material (HAM, greenery on the surface and on the roofs (VEG, and a combination of them (HYBRID has been studied using simulation with the microscale model ENVI-met. All three strategies show higher cooling effect in the daytime. The average nocturnal cooling effect of VEG and HYBRID (0.92, 1.10 K is much higher than HAM (0.16 K, although high-density trees show a negative effect on nocturnal cooling.

  20. Mitigating Doppler shift effect in HF multitone data modem (United States)

    Sonlu, Yasar


    Digital communications over High Frequency (HF) radio channels are getting important in recent years. Current HF requirements are for data transmission at rates 2.4 kbps or more to accommodate computer data links and digital secure voice. HF modems which were produced to meet these speeds are, serial modems and parallel modems. On the other hand, the HF sky-wave communication medium, the ionosphere, has some propagation problems such as multipath and Doppler shift. The effect of Doppler shift in a parallel modem which employs Differential Quadrature Phase Shift Keying (DQPSK) modulation is considered and a correction method to mitigate the Doppler Shift effect is introduced.

  1. Analysis of landslide mitigation effects using Ground Penetrating Radar (United States)

    Ristic, Aleksandar; Govedarica, Miro; Vrtunski, Milan; Petrovacki, Dusan


    Area of Ground Penetrating Radar (GPR) technology applications becomes wider nowadays. It includes utility mapping as important part of civil engineering applications, geological structure and soil analyses, applications in agriculture, etc. Characteristics of the technology make it suitable for structure analysis of shallow landslides, whose number and impact on environment is dominant in the region. Especially when shallow landslide endangers some man-made structures such as buildings, roads or bridges, analysis of GPR data can yield very useful results. The results of GPR data analysis of the shallow landslide are represented here. It is situated on the mountain Fruska Gora in Serbia. Despite its dimensions (50x20m) this landslide was interesting for analysis for two reasons: - The landslide occurred at the part of the single road between the cement factory and the marl mine. The cement factory "Lafarge" in Beocin (Fruska Gora) is the largest cement manufacturer in the country. One of major priorities of the factory management is to keep the function of this road. The road is heavily exploited and over the years it led to landslide movements and damaging of the road itself. - The landslide dates back to earlier period and the mitigation measures were performed twice. Laying the foundation of the retaining wall was not performed during the first mitigation measures. The second mitigation measures were performed in 2010 and included detailed geotechnical analysis of the location with the appropriate foundation laying. Since the GPR technology can produce high resolution images of subsurface it provides clear insight into the current state of surveyed location. That kind of analysis is necessary to maintain permanent functionality of the road and to check the status of mitigation measures. Furthermore, the location characteristics do not allow easy access so the possibilities of other analysis technologies application are limited. In order to assess the effects of

  2. Mitigation of Blast Effects on Aluminum Foam Protected Masonry Walls

    Institute of Scientific and Technical Information of China (English)

    SU Yu; WU Chengqing; GRIFFITH Mike


    Terrorist attacks using improvised explosive devices (lED) can result in unreinforced masonry (URM) wall collapse.Protecting URM wall from lED attack is very complicated.An effective solution to mitigate blast effects on URM wall is to retrofit URM walls with metallic foam sheets to absorb blast energy.However,mitigation of blast effects on metallic foam protected URM walls is currently in their infancy in the world.In this palaer,numerical models are used to simulate the performance of aluminum foam protected URM walls subjected to blast loads.A distinctive model,in which mortar and brick units of masonry are discritized individually,is used to model the performance of masonry and the contact between the masonry and steel face-sheet of aluminum foam is modelled using the interface element model.The aluminum foam is modelled by a nonlinear elastoplastic material model.The material models for masonry,aluminum foam and interface are then coded into a finite element program LS-DYNA3D to perform the numerical calculations of response and damage of aluminum foam protected URM walls under airblast loads.Discussion is made on the effectiveness of the aluminum foam protected system for URM wall against blast loads.

  3. Green Roof Technology- Mitigate Urban Heat Island (UHI Effect

    Directory of Open Access Journals (Sweden)

    Odli Z.S. M.


    Full Text Available Alterations on the land surfaces, which are attributed by human activities, especially in cities, cause many implications to the ecosystem. The increase of buildings in cities is reflecting the growth of human activities resulted in a significant temperature increase and warmer pattern in the urban area than the surrounding countryside. The phenomenon defined as urban heat island. This study investigates the application and efficiency of the green roof as an approach to mitigate urban heat island and reducing indoor temperature in a building. Two types of roof models, which consist of vegetative roof and non-vegetative roof, were built to investigate the efficiency of vegetated roof in reducing indoor temperature compared to the non-vegetated roof. The outdoor and indoor temperature and humidity of each roof model were monitored by using RH520 Thermo Hygrometer. The data was collected for three times in a week for 9 weeks at 9:00am to 5:00pm. It was found that the indoor average temperature data for vegetative roof could be reduced 2.4°C from the outdoor average temperature and 0.8°C for non-vegetative roof. The difference of temperature reduction for vegetative roof was greater than the nonvegetative roof, thus indicate that green roof was highly efficient in reducing indoor temperature and mitigate urban heat island impact.

  4. Strain Rate Effects in CFRP Used For Blast Mitigation

    Directory of Open Access Journals (Sweden)

    Sarah. L. Orton


    Full Text Available The purpose of this research is to gain a better understanding of strain rate effects in carbon fiber reinforced polymer (CFRP laminates exposed to blast loading. The use of CFRP offers an attractive option for mitigating structures exposed to blasts. However, the effect of high strain rates in CFRP composites commonly used in the civil industry is unknown. This research conducted tensile tests of 21 CFRP coupons using a hydraulically powered dynamic loader. The strain rates ranged from 0.0015 s−1 to 7.86 s−1 and are representative of strain rates that CFRP may see in a blast when used to strengthen reinforced concrete structures. The results of the testing showed no increase in the tensile strength or stiffness of the CFRP at the higher strain rates. In addition, the results showed significant scatter in the tensile strengths possibly due to the rate of loading or manufacture of the coupon.

  5. Mitigating the effects of measurement noise on Granger causality

    CERN Document Server

    Nalatore, Hariharan; Ding, Mingzhou


    Computing Granger causal relations among bivariate experimentally observed time series has received increasing attention over the past few years. Such causal relations, if correctly estimated, can yield significant insights into the dynamical organization of the system being investigated. Since experimental measurements are inevitably contaminated by noise, it is thus important to understand the effects of such noise on Granger causality estimation. The first goal of this paper is to provide an analytical and numerical analysis of this problem. Specifically, we show that, due to noise contamination, (1) spurious causality between two measured variables can arise and (2) true causality can be suppressed. The second goal of the paper is to provide a denoising strategy to mitigate this problem. Specifically, we propose a denoising algorithm based on the combined use of the Kalman filter theory and the Expectation-Maximization (EM) algorithm. Numerical examples are used to demonstrate the effectiveness of the den...

  6. Electrodes mitigating effects of defects in organic electronic devices (United States)

    Heller, Christian Maria Anton


    A compound electrode for organic electronic devices comprises a thin first layer of a first electrically conducting material and a second electrically conducting material disposed on the first layer. In one embodiment, the second electrically conducting material is formed into a plurality of elongated members. In another embodiment, the second material is formed into a second layer. The elongated members or the second layer has a thickness greater than that of the first layer. The second layer is separated from the first layer by a conducting material having conductivity less than at least the material of the first layer. The compound electrode is capable of mitigating adverse effects of defects, such as short circuits, in the construction of the organic electronic devices, and can be included in light-emitting or photovoltaic devices.

  7. Waveguide generated mitigation of speckle and scintillation on an actively illuminated target (United States)

    Moore, Trevor D.; Raynor, Robert A.; Spencer, Mark F.; Schmidt, Jason D.


    Active illumination is often used when passive illumination cannot produce enough signal intensity to be a reliable imaging method. However, an increase in signal intensity is often achieved by using highly coherent laser sources, which produce undesirable effects such as speckle and scintillation. The deleterious effects of speckle and scintillation are often so immense that the imaging camera cannot receive intelligible data, thereby rendering the active illumination technique useless. By reducing the spatial coherence of the laser beam that is actively illuminating the object, it is possible to reduce the corruption of the received data caused by speckle and scintillation. The waveguide method discussed in this paper reduces spatial coherence through multiple total internal reflections, which create multiple virtual sources of diverse path lengths. The differing path lengths between the virtual sources and the target allow for the temporal coherence properties of the laser to be translated into spatial coherence properties. The resulting partial spatial coherence helps to mitigate the self-interference of the beam as it travels through the atmosphere and reflects off of optically rough targets. This mitigation method results in a cleaner, intelligible image that may be further processed for the intended use, unlike its unmitigated counterpart. Previous research has been done to independently reduce speckle or scintillation by way of spatial incoherence, but there has been no focus on modeling the waveguide, specifically the image plane the waveguide creates. Utilizing a ray-tracing method we can determine the coherence length of the source necessary to create incoherent spots in the image plane, as well as accurately modeling the image plane.

  8. Feasibility of mitigating the effects of windfarms on primary radar

    Energy Technology Data Exchange (ETDEWEB)

    Butler, M.M.; Johnson, D.A.


    The objectives of the study were to investigate the feasibility of modifying civil and military radars to mitigate the effects from wind turbines, to provide costings for implementing changes to the radar and to produce guidelines for planning wind farms in the vicinity of radars. The effect of wind turbines on radar signals, assessed through computer modelling, is summarised. The key aspects of turbine design that can be modified to minimise these effects are described. A key issue is the fact that no two radar installations are alike, with settings being customised for local requirements. As a consequence, a detailed understanding of the design and features of each individual radar would be required in order to assess the impact of a wind farm proposal. The costs of a programme of modifications to the civil ATC (air traffic control) radar base will depend on many factors. An estimate of costs is provided, based on the assumption that only 30 of the UK radars would need modification and that a range of modifications from very simple to very complex will be required. A number of other approaches, outside of modification of the radar system, may require investigation during a windfarm planning application, such as layout and location of the wind farm or changing air traffic routes in the vicinity of the wind farm.

  9. The Effects of Stress Mitigation on Nondestructive Examination

    Energy Technology Data Exchange (ETDEWEB)

    Dennis C. Kunerth; Eric D. Larsen; Timothy R. Mcjunkin; Arthur D. Watkins


    Ultrasonic volumetric and eddy current and visual profile surface inspections of the completed weld securing the outer lid of the Yucca Mountain waste package are required after stress mitigation. However, the technique implemented may affect the ability of the different evaluation techniques to properly characterize the completed weld. An evaluation was performed to determine the extent the nondestructive evaluation techniques are affected by two candidate mitigation processes: controlled plasticity burnishing and laser peening. This report describes the work performed and summarizes the results.

  10. Carbon footprint mitigation on vacation : A norm activation model

    NARCIS (Netherlands)

    Vaske, J.J.; Jacobs, M.H.; Espinosa, T.K.


    The norm activation theory and past research suggest that ecologically appropriate behaviors increase when individuals (a) ascribe personal responsibility (AR) to protect the environment and (b) are aware of the consequences (AC) of their actions. We examined the influence of AR and AC on ecological

  11. An Integrated Assessment of Water Scarcity Effects on Energy and Land Use Decisions and Mitigation Policies (United States)

    Hejazi, M. I.; Kim, S. H.; Liu, L.; Liu, Y.; Calvin, K. V.; Leon, C.; Edmonds, J.; Kyle, P.; Patel, P.; Wise, M. A.; Davies, E. G.


    Water is essential for the world's food supply, for energy production, including bioenergy and hydroelectric power, and for power system cooling. Water is already scarce in many regions and could present a critical constraint as society attempts simultaneously to mitigate climate forcing and adapt to climate change, and to provide food for an increasing population. We use the Global Change Assessment Model (GCAM), where interactions between population, economic growth, energy, land and water resources interact simultaneously in a dynamically evolving system, to investigate how water scarcity affects energy and land use decisions as well as mitigation policies. In GCAM, competing claims on water resources from all claimants—energy, land, and economy—are reconciled with water resource availability—from renewable water, non-renewable groundwater sources and desalinated water—across 235 major river basins. Limits to hydrologic systems have significant effects on energy and land use induced emissions via constraints on decisions of their use. We explore these effects and how they evolve under climate change mitigation policies, which can significantly alter land use patterns, both by limiting land use change emissions and by increasing bioenergy production. The study also explores the mitigation scenarios in the context of the shared socioeconomic pathways (SSPs). We find that previous estimates of global water withdrawal projections are overestimated, as our simulations show that it is more economical in some basins to alter agricultural and energy activities rather than utilize non-renewable groundwater or desalinated water. This study highlights the fact that water is a binding factor in agriculture, energy and land use decisions in integrated assessment models (IAMs), and stresses the crucial role of water in regulating agricultural commodities trade and land-use and energy decisions.

  12. Climate Change Mitigation Activities in the Philippine Forestry Sector. Application of the COMAP Model

    Energy Technology Data Exchange (ETDEWEB)

    Lasco, Rodel D.; Pulhin, Florencia B. [Environmental Forestry Programme (ENFOR), College of Forestry and Natural Resources, University of the Philippines at Los Banos College, 4031 Laguna (Philippines)


    The forest sector in the Philippines has the potential to be a major sink for carbon (C). The present study was conducted to evaluate potential forestry mitigation options in the Philippines using the Comprehensive Mitigation Assessment Process (COMAP) model. The baseline scenario (BAU) assumes that current trends continue up to the year 2030 ('business-as-usual'). Two mitigation scenarios were evaluated: high scenario (HS) and low scenario (LS). The former is patterned largely from the government's forest master plan while the latter assumes a 50% lower success rate of the master plan. The results of the analyses show that by 2030, the total C stock of the Philippine forest sector in the baseline scenario decreases to 814 x 10{sup 6} Mg C, down by 37% compared to the 1990 level. The C stocks of the HS and LS mitigation scenarios were 22% and 18% higher than the BAU, respectively. Of the mitigation options assessed, long rotation plantations and forest protection activities produce the greatest C gain (199 and 104 x 10{sup 6} Mg, respectively under HS). The not present value (NPV) of benefits is highest in the bioenergy option with $24.48 per Mg C (excluding opportunity costs) at a real discount rate of 12%. However, the investment and life cycle costs are also highest using bioenergy. The study also estimated potential investments needed under the mitigation scenarios. The investment requirement for the LS amounts to $263 x 10{sup 6} while for the HS it is $748 x 10{sup 6}. Finally, policy issues and decisions that may be useful for the Philippines to evaluate LULUCF mitigation options under the UNFCCC Kyoto Protocol, are identified and discussed. 30 refs.

  13. Olive Oil effectively mitigates ovariectomy-induced osteoporosis in rats

    Directory of Open Access Journals (Sweden)

    Saleh Hanan A


    Full Text Available Abstract Background Osteoporosis, a reduction in bone mineral density, represents the most common metabolic bone disease. Postmenopausal women are particularly susceptible to osteoporosis when their production of estrogen declines. For these women, fracture is a leading cause of morbidity and mortality. This study was conducted to evaluate the protective effects of olive oil supplementation against osteoporosis in ovariectomized (OVX rats. Methods We studied adult female Wistar rats aged 12-14 months, divided into three groups: sham-operated control (SHAM, ovariectomized (OVX, and ovariectomized rats supplemented with extravirgin olive oil (Olive-OVX orally for 12 weeks; 4 weeks before ovariectomy and 8 weeks after. At the end of the experiment, blood samples were collected. Plasma levels of calcium, phosphorus, alkaline phosphatase (ALP, malondialdehyde (MDA, and nitrates were assayed. Specimens from both the tibia and the liver were processed for light microscopic examination. Histomorphometric analysis of the tibia was also performed. Results The OVX-rats showed a significant decrease in plasma calcium levels, and a significant increase in plasma ALP, MDA, and nitrates levels. These changes were attenuated by olive oil supplementation in the Olive-OVX rats. Light microscopic examination of the tibia of the OVX rats revealed a significant decrease in the cortical bone thickness (CBT and the trabecular bone thickness (TBT. In addition, there was a significant increase in the osteoclast number denoting bone resorption. In the Olive-OVX rats these parameters were markedly improved as compared to the OVX group. Examination of the liver specimens revealed mononuclear cellular infiltration in the portal areas in the OVX-rats which was not detected in the Olive-OVX rats. Conclusions Olive oil effectively mitigated ovariectomy-induced osteoporosis in rats, and is a promising candidate for the treatment of postmenopausal osteoporosis.

  14. 76 FR 14413 - Risk Mitigation Strategies To Address Potential Procoagulant Activity in Immune Globulin... (United States)


    ...) pathophysiology of arterial and venous thrombosis in this context; (3) research to identify specific procoagulant...) the role of activated Coagulation Factor XIa in IGIV-associated thrombosis; (6) test methods for... HUMAN SERVICES Food and Drug Administration Risk Mitigation Strategies To Address Potential...

  15. Assessment of Management to Mitigate Anthropogenic Effects on Large Whales (United States)

    Van Der Hoop, Julie M; Moore, Michael J; Barco, Susan G; Cole, Timothy VN; Daoust, Pierre-Yves; Henry, Allison G; McAlpine, Donald F; McLellan, William A; Wimmer, Tonya; Solow, Andrew R


    Abstract United States and Canadian governments have responded to legal requirements to reduce human-induced whale mortality via vessel strikes and entanglement in fishing gear by implementing a suite of regulatory actions. We analyzed the spatial and temporal patterns of mortality of large whales in the Northwest Atlantic (23.5°N to 48.0°N), 1970 through 2009, in the context of management changes. We used a multinomial logistic model fitted by maximum likelihood to detect trends in cause-specific mortalities with time. We compared the number of human-caused mortalities with U.S. federally established levels of potential biological removal (i.e., species-specific sustainable human-caused mortality). From 1970 through 2009, 1762 mortalities (all known) and serious injuries (likely fatal) involved 8 species of large whales. We determined cause of death for 43% of all mortalities; of those, 67% (502) resulted from human interactions. Entanglement in fishing gear was the primary cause of death across all species (n = 323), followed by natural causes (n = 248) and vessel strikes (n = 171). Established sustainable levels of mortality were consistently exceeded in 2 species by up to 650%. Probabilities of entanglement and vessel-strike mortality increased significantly from 1990 through 2009. There was no significant change in the local intensity of all or vessel-strike mortalities before and after 2003, the year after which numerous mitigation efforts were enacted. So far, regulatory efforts have not reduced the lethal effects of human activities to large whales on a population-range basis, although we do not exclude the possibility of success of targeted measures for specific local habitats that were not within the resolution of our analyses. It is unclear how shortfalls in management design or compliance relate to our findings. Analyses such as the one we conducted are crucial in critically evaluating wildlife-management decisions. The results of these analyses can

  16. Active Amplification of the Terrestrial Albedo to Mitigate Climate Change: An Exploratory Study

    CERN Document Server

    Hamwey, R M


    This study explores the potential to enhance the reflectance of solar insolation by the human settlement and grassland components of the Earth's terrestrial surface as a climate change mitigation measure. Preliminary estimates derived using a static radiative transfer model indicate that such efforts could amplify the planetary albedo enough to offset the current global annual average level of radiative forcing caused by anthropogenic greenhouse gases by as much as 30 percent or 0.76 W/m2. Terrestrial albedo amplification may thus extend, by about 25 years, the time available to advance the development and use of low-emission energy conversion technologies which ultimately remain essential to mitigate long-term climate change. However, additional study is needed to confirm the estimates reported here and to assess the economic and environmental impacts of active land-surface albedo amplification as a climate change mitigation measure.

  17. Flight path-driven mitigation of wavefront curvature effects in SAR images (United States)

    Doerry, Armin W.


    A wavefront curvature effect associated with a complex image produced by a synthetic aperture radar (SAR) can be mitigated based on which of a plurality of possible flight paths is taken by the SAR when capturing the image. The mitigation can be performed differently for different ones of the flight paths.

  18. Modeling the Heterogeneous Effects of GHG Mitigation Policies on Global Agriculture and Forestry (United States)

    Golub, A.; Henderson, B.; Hertel, T. W.; Rose, S. K.; Sohngen, B.


    Agriculture and forestry are envisioned as potentially key sectors for climate change mitigation policy, yet the depth of analysis of mitigation options and their economic consequences remains remarkably shallow in comparison to that for industrial mitigation. Farming and land use change - much of it induced by agriculture -account for one-third of global greenhouse gas (GHG) emissions. Any serious attempt to curtail these emissions will involve changes in the way farming is conducted, as well as placing limits on agricultural expansion into areas currently under more carbon-intensive land cover. However, agriculture and forestry are extremely heterogeneous, both in the technology and intensity of production, as well as in the GHG emissions intensity of these activities. And these differences, in turn, give rise to significant changes in the distribution of agricultural production, trade and consumption in the wake of mitigation policies. This paper assesses such distributional impacts via a global economic analysis undertaken with a modified version of the GTAP model. The paper builds on a global general equilibrium GTAP-AEZ-GHG model (Golub et al., 2009). This is a unified modeling framework that links the agricultural, forestry, food processing and other sectors through land, and other factor markets and international trade, and incorporates different land-types, land uses and related CO2 and non-CO2 GHG emissions and sequestration. The economic data underlying this work is the global GTAP data base aggregated up to 19 regions and 29 sectors. The model incorporates mitigation cost curves for different regions and sectors based on information from the US-EPA. The forestry component of the model is calibrated to the results of the state of the art partial equilibrium global forestry model of Sohngen and Mendelson (2007). Forest carbon sequestration at both the extensive and intensive margins are modeled separately to better isolate land competition between

  19. Effectiveness of carcass removal for mitigating avian botulism in prairie-pothole wetlands (United States)

    US Fish and Wildlife Service, Department of the Interior — Final report on a project to determine if refuge standard operational procedures for carcass pick-up are effective at mitigating avian botulism in the Sand Lake...

  20. Effectiveness of emergent and submergent aquatic plants in mitigating a nitrogen-permethrin mixture (United States)

    The current study assessed the effectiveness of varying combinations of two common aquatic vascular macrophytes, parrot feather (Myriophyllum aquaticum) and cattail (Typha latifolia) for mitigating contamination from a mixture of nitrogen (ammonium nitrate) and permethrin. Hydraulically connected we...

  1. Modeling effectiveness of gradual increases in source level to mitigate effects of sonar on marine mammals. (United States)

    Von Benda-Beckmann, Alexander M; Wensveen, Paul J; Kvadsheim, Petter H; Lam, Frans-Peter A; Miller, Patrick J O; Tyack, Peter L; Ainslie, Michael A


    Ramp-up or soft-start procedures (i.e., gradual increase in the source level) are used to mitigate the effect of sonar sound on marine mammals, although no one to date has tested whether ramp-up procedures are effective at reducing the effect of sound on marine mammals. We investigated the effectiveness of ramp-up procedures in reducing the area within which changes in hearing thresholds can occur. We modeled the level of sound killer whales (Orcinus orca) were exposed to from a generic sonar operation preceded by different ramp-up schemes. In our model, ramp-up procedures reduced the risk of killer whales receiving sounds of sufficient intensity to affect their hearing. The effectiveness of the ramp-up procedure depended strongly on the assumed response threshold and differed with ramp-up duration, although extending the duration of the ramp up beyond 5 min did not add much to its predicted mitigating effect. The main factors that limited effectiveness of ramp up in a typical antisubmarine warfare scenario were high source level, rapid moving sonar source, and long silences between consecutive sonar transmissions. Our exposure modeling approach can be used to evaluate and optimize mitigation procedures.

  2. RFI Mitigation Workshop (United States)


    The increased sensitivity of passive instrumentation in radio astronomy and remote sensing and the intensifying active use of the spectrum have led to an increasing level of radio frequency interference (RFI) of the active services on the passive use of the spectrum. Advances in technology and computing have opened up new possibilities for mitigating the effects of certain classes of interference in the observing data. Interference in allocated bands always leads to data loss for the passive users of the spectrum even if interference mitigation is applied. However, interference mitigation in non-allocated spectral bands may facilitate the partial use of this spectrum for passive (non-interfering) observations. There is no generic method to mitigate all types of interference, so a multi-layered system approach may be advisable to reduce detrimental effects for a congested interference environment. Specific mitigation methods implemented at different points in the data acquisition chain will thus result in a cumulative mitigation effect on the data. This third RFI Mitigation Workshop considered RFI mitigation in radio astronomy in all its facets with the aim of facilitating the implementation of instrumental and data processing techniques. This workshop aimed to take a forward look at applications for the next generation of radio instruments, such as the SKA and its pathfinders and LOFAR, as well as considering their application to existing instruments. This workshop has been organized by ASTRON and NAIC, with support from the Engineering Forum of FP7 RadioNet, the SKA Project Development Office, and in collaboration with CRAF and IUCAF.

  3. Multiple mitigation mechanisms: Effects of submerged plants on the toxicity of nine insecticides to aquatic animals. (United States)

    Brogan, William R; Relyea, Rick A


    Understanding the processes that regulate contaminant impacts in nature is an increasingly important challenge. For insecticides in surface waters, the ability of aquatic plants to sorb, or bind, hydrophobic compounds has been identified as a primary mechanism by which toxicity can be mitigated (i.e. the sorption-based model). However, recent research shows that submerged plants can also rapidly mitigate the toxicity of the less hydrophobic insecticide malathion via alkaline hydrolysis (i.e. the hydrolysis-based model) driven by increased water pH resulting from photosynthesis. However, it is still unknown how generalizable these mitigation mechanisms are across the wide variety of insecticides applied today, and whether any general rules can be ascertained about which types of chemicals may be mitigated by each mechanism. We quantified the degree to which the submerged plant Elodea canadensis mitigated acute (48-h) toxicity to Daphnia magna using nine commonly applied insecticides spanning three chemical classes (carbamates: aldicarb, carbaryl, carbofuran; organophosphates: malathion, diazinon, chlorpyrifos; pyrethroids: permethrin, bifenthrin, lambda-cyhalothrin). We found that insecticides possessing either high octanol-water partition coefficients (log Kow) values (i.e. pyrethroids) or high susceptibility to alkaline hydrolysis (i.e. carbamates and malathion) were all mitigated to some degree by E. canadensis, while the plant had no effect on insecticides possessing intermediate log Kow values and low susceptibility to hydrolysis (i.e. chlorpyrifos and diazinon). Our results provide the first general insights into which types of insecticides are likely to be mitigated by different mechanisms based on known chemical properties. We suggest that current models and mitigation strategies would be improved by the consideration of both mitigation models.

  4. General equilibrium effects of a supply side GHG mitigation option under the Clean Development Mechanism. (United States)

    Timilsina, Govinda R; Shrestha, Ram M


    The Clean Development Mechanism (CDM) under the Kyoto Protocol to the United Nations Framework Convention on Climate Change is considered a key instrument to encourage developing countries' participation in the mitigation of global climate change. Reduction of greenhouse gas (GHG) emissions through the energy supply and demand side activities are the main options to be implemented under the CDM. This paper analyses the general equilibrium effects of a supply side GHG mitigation option-the substitution of thermal power with hydropower--in Thailand under the CDM. A static multi-sector general equilibrium model has been developed for the purpose of this study. The key finding of the study is that the substitution of electricity generation from thermal power plants with that from hydropower plants would increase economic welfare in Thailand. The supply side option would, however, adversely affect the gross domestic product (GDP) and the trade balance. The percentage changes in economic welfare, GDP and trade balance increase with the level of substitution and the price of certified emission reduction (CER) units.

  5. The Effects of Mitigation Measures on Flood Damage Prevention in Korea

    Directory of Open Access Journals (Sweden)

    Cheol-Hee Son


    Full Text Available This study analyzed the characteristics of flood damages and the effects of structural and non-structural flood damage mitigation measures in Korea. First, a theoretical discussion of the structural and non-structural measures to mitigate flood damages was used to select the variables and devise the hypotheses. An analysis was conducted using the Auto-Regressive Integrated Moving-Average (ARIMA time series methodology, Korean socioeconomic data, and damage characteristics of major flood events. The effects of flood damage mitigation measures on the extent of flood damages were assessed using an intervention time series model. The major findings were that the intervention effects of structural and non-structural measures were statistically significant from 1958 to 2013 (a period of 55 years and that while the former were ineffective at mitigating flood damages, the latter were successful in doing so. Based on the above findings, policy suggestions for future flood damage mitigation measures in Korea were offered. For structural measures, the government should manage its existing facilities, recover ecosystems of damaged rivers, and devise mitigation measures for urban areas. For non-structural measures, the government should enhance its flood forecasting capacity, revise laws related to flood control and prevention, and update and rationalize land-use plans.

  6. Aircraft noise effects on sleep: Mechanisms, mitigation and research needs

    Directory of Open Access Journals (Sweden)

    Mathias Basner


    Full Text Available There is an ample number of laboratory and field studies which provide sufficient evidence that aircraft noise disturbs sleep and, depending on traffic volume and noise levels, may impair behavior and well-being during the day. Although clinical sleep disorders have been shown to be associated with increased risk of cardiovascular diseases, only little is known about the long-term effects of aircraft noise disturbed sleep on health. National and international laws and guidelines try to limit aircraft noise exposure facilitating active and passive noise control to prevent relevant sleep disturbances and its consequences. Adopting the harmonized indicator of the European Union Directive 2002/49/EC, the WHO Night Noise Guideline for Europe (NNG defines four Lnight , outside ranges associated with different risk levels of sleep disturbance and other health effects ( 55 dBA. Although traffic patterns differing in number and noise levels of events that lead to varying degrees of sleep disturbance may result in the same Lnight , simulations of nights with up to 200 aircraft noise events per night nicely corroborate expert opinion guidelines formulated in WHO′s NNG. In the future, large scale field studies on the effects of nocturnal (aircraft noise on sleep are needed. They should involve representative samples of the population including vulnerable groups like children and chronically ill subjects. Optimally, these studies are prospective in nature and examine the long-term consequences of noise-induced sleep disturbances. Furthermore, epidemiological case-control studies on the association of nocturnal (aircraft noise exposure and cardiovascular disease are needed. Despite the existing gaps in knowledge on long-term health effects, sufficient data are available for defining limit values, guidelines and protection concepts, which should be updated with the availability of new data.

  7. Refreshing the role of open water surfaces on mitigating the maximum urban heat island effect

    NARCIS (Netherlands)

    Steeneveld, G.J.; Koopmans, S.; Heusinkveld, B.G.; Theeuwes, N.E.


    During warm summer episodes citizens in urban areas are subject to reduced human thermal comfort and negative health effects. To mitigate these adverse effects, land use planners and urban designers have used the evaporative power of water bodies as a tool to limit the urban heat island effect (UHI)

  8. Downstream Intensification Effects Associated with CO2 Laser Mitigation of Fused Silica

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, M J; Bass, I L; Guss, G M; Widmayer, C C; Ravizza, F L


    Mitigation of 351nm laser-induced damage sites on fused silica exit surfaces by selective CO{sub 2} treatment has been shown to effectively arrest the exponential growth responsible for limiting the lifetime of optics in high-fluence laser systems. However, the perturbation to the optical surface profile following the mitigation process introduces phase contrast to the beam, causing some amount of downstream intensification with the potential to damage downstream optics. Control of the laser treatment process and measurement of the associated phase modulation is essential to preventing downstream 'fratricide' in damage-mitigated optical systems. In this work we present measurements of the surface morphology, intensification patterns and damage associated with various CO{sub 2} mitigation treatments on fused silica surfaces. Specifically, two components of intensification pattern, one on-axis and another off-axis can lead to damage of downstream optics and are related to rims around the ablation pit left from the mitigation process. It is shown that control of the rim structure around the edge of typical mitigation sites is crucial in preventing damage to downstream optics.

  9. Quantitative analysis on the urban flood mitigation effect by the extensive green roof system. (United States)

    Lee, J Y; Moon, H J; Kim, T I; Kim, H W; Han, M Y


    Extensive green-roof systems are expected to have a synergetic effect in mitigating urban runoff, decreasing temperature and supplying water to a building. Mitigation of runoff through rainwater retention requires the effective design of a green-roof catchment. This study identified how to improve building runoff mitigation through quantitative analysis of an extensive green-roof system. Quantitative analysis of green-roof runoff characteristics indicated that the extensive green roof has a high water-retaining capacity response to rainfall of less than 20 mm/h. As the rainfall intensity increased, the water-retaining capacity decreased. The catchment efficiency of an extensive green roof ranged from 0.44 to 0.52, indicating reduced runoff comparing with efficiency of 0.9 for a concrete roof. Therefore, extensive green roofs are an effective storm water best-management practice and the proposed parameters can be applied to an algorithm for rainwater-harvesting tank design.

  10. Numerical Simulation of Water Mitigation Effects on Shock Wave with SPH Method

    Institute of Scientific and Technical Information of China (English)

    MAO Yiming; FANG Qin; ZHANG Yadong; GAO Zhenru


    The water mitigation effect on the propagation of shock wave was investigated numerically.The traditionaf smoothed particle hydrodynamics(SPH)method was modified based on Riemann solution.The comparison of numerical results with the analytical solution indicated that the modified SPH method has more advantages than the traditional SPH method.Using the modified SPH algorithm.a series of one-dimensional planar wave propagation problems were investigated,focusing on the influence of the air-gap between the high-pressure air and water and the thickness of water.The humerical results showed that water mitigation effect is significant.Up to 60%shock wave pressure reduction could be achieved with the existence of water.and the shape of shock wave was also changed greatly.It is seemly that fhe small air-gap between the high-pressure air and water has more influence on water mitigation effect.

  11. Interventions to Mitigate the Psychological Effects of Media Violence on Aggressive Behavior. (United States)

    Eron, Leonard D.


    Describes and evaluates attempts to mitigate effect that watching television violence has on young children. Most relevant studies have been laboratory experiments, and there is no reported evidence that any intervention has been effective over long-term. Concludes that interventions combining cognitive and behavioral approaches have most promise,…

  12. Doubly Fed Induction Generator Based Wind Turbine Associated to a Shunt Active Power Filter for Current Harmonics Mitigation

    Directory of Open Access Journals (Sweden)

    Samira Dib,


    Full Text Available Integration of wind turbine based on doubly fed induction generator (DFIG into the electrical grid has become an important part of electrical generation in many countries and its importance is continuing to increase. The advantages of using a DFIG instead of other generators are already well known. A few of them are variousspeed generations, the decoupled control of active and reactive power and high power capacity. However, the ever-growing proliferation of power electronics based devices for source conditioning and motion control in modern industrial applications has increased the occurrence of harmonic currents in distribution systems. This harmonics have harmful and costly effects on DFIG such as, the increase of stator and rotor core losses and the increase of the operating temperature. In this paper, a shunt active power filter (SAPF is proposed to mitigate current harmonics generated by nonlinear loads and keeps the current at the point of common coupling (PCC sinusoidal. The simulation results using MATLAB/SIMULINK show a good performance of the SAPF for current harmonics mitigation.

  13. 78 FR 50435 - Agency Information Collection Activities; Proposed Collection; Comment Request: FEMA Mitigation... (United States)


    ... successful mitigation and flood insurance practices occurring in communities nationwide and provides a method...-0-25, Mitigation Best Practice Submission Worksheet. Abstract: FEMA uses the information provided... $616.20 Tribal Government. Individual or households; State, local or Mitigation Best Practice 45 1 45...

  14. Effective Antibiotic Resistance Mitigation during Cheese Fermentation ▿


    Li, Xinhui; Li, Yingli; Alvarez, Valente; Harper, Willis James; Wang, Hua H.


    Controlling antibiotic-resistant (ART) bacteria in cheese fermentation is important for food safety and public health. A plant-maintained culture was found to be a potential source for ART bacterial contamination in cheese fermentation. Antibiotics had a detectable effect on the ART population from contamination in the finished product. The decrease in the prevalence of antibiotic resistance (AR) in retail cheese samples from 2010 compared to data from 2006 suggested the effectiveness of targ...

  15. Potassium fertilization mitigates the adverse effects of drought on selected Zea mays cultivars (United States)

    In the present study, the role of potassium (K) in mitigating the adverse effects of drought stress (DS) on 2 maize (Zea mays L.) cultivars, ‘Shaandan 9’ (S9; drought-tolerant) and ‘Shaandan 911’ (S911; drought-sensitive), was assessed. K application increased dry matter (DM) across all growth stage...

  16. Mitigating the Effects of Negative Stereotyping of Aging and the Elderly in Primary Grade Reading Instruction. (United States)

    Gutknecht, Bruce


    Discusses depictions of aging and the elderly in primary grade reading instructional materials. Investigates the attitudes of primary grade students toward aging and the elderly. Suggests instructional approaches and materials that can mitigate the effects of negative stereotyping of aging and the elderly. (RS)

  17. The Effect of Greenhouse Gas Mitigation on Drought Impacts in the U.S. (United States)

    In this paper, we present a methodology for analyzing the economic benefits in the U.S. of changes in drought frequency and severity due to global greenhouse gas (GHG) mitigation. We construct reduced-form models of the effect of drought on agriculture and reservoir recreation i...

  18. Yeast probiotic supplementation mitigates some of the negative effects of heat stress in feedlot heifers (United States)

    Heat stress (HS) in feedlot cattle can be detrimental to performance, health and profitability; however, utilization of feed additives has the potential to mitigate some of these negative effects. Therefore, this study was designed to determine if supplementation of a combination live yeast and ye...

  19. Why herd size matters - mitigating the effects of livestock crashes.

    Directory of Open Access Journals (Sweden)

    Marius Warg Næss

    Full Text Available Analysing the effect of pastoral risk management strategies provides insights into a system of subsistence that have persevered in marginal areas for hundreds to thousands of years and may shed light into the future of around 200 million households in the face of climate change. This study investigated the efficiency of herd accumulation as a buffer strategy by analysing changes in livestock holdings during an environmental crisis in the Saami reindeer husbandry in Norway. We found a positive relationship between: (1 pre- and post-collapse herd size; and (2 pre-collapse herd size and the number of animals lost during the collapse, indicating that herd accumulation is an effective but costly strategy. Policies that fail to incorporate the risk-beneficial aspect of herd accumulation will have a limited effect and may indeed fail entirely. In the context of climate change, official policies that incorporate pastoral risk management strategies may be the only solution for ensuring their continued existence.

  20. Reduced greenhouse gas mitigation potential of no-tillage soils through earthworm activity. (United States)

    Lubbers, Ingrid M; van Groenigen, Kees Jan; Brussaard, Lijbert; van Groenigen, Jan Willem


    Concerns about rising greenhouse gas (GHG) concentrations have spurred the promotion of no-tillage practices as a means to stimulate carbon storage and reduce CO2 emissions in agro-ecosystems. Recent research has ignited debate about the effect of earthworms on the GHG balance of soil. It is unclear how earthworms interact with soil management practices, making long-term predictions on their effect in agro-ecosystems problematic. Here we show, in a unique two-year experiment, that earthworm presence increases the combined cumulative emissions of CO2 and N2O from a simulated no-tillage (NT) system to the same level as a simulated conventional tillage (CT) system. We found no evidence for increased soil C storage in the presence of earthworms. Because NT agriculture stimulates earthworm presence, our results identify a possible biological pathway for the limited potential of no-tillage soils with respect to GHG mitigation.

  1. Rollover Mitigation Controller Development for Three-Wheeled Vehicle Using Active Front Steering

    Directory of Open Access Journals (Sweden)

    Raja Amer Azim


    Full Text Available Three-wheeled vehicles are agile, less complex, but relatively more prone to rollover. The current study focuses on the rollover mitigation control design using active front steering for such vehicles. A lateral load transfer ratio (LLTR adapted for a three-wheeled platform is presented. Sliding mode control design strategy has been devised which results in pseudo-direct control for roll dynamics of the vehicle. The lag in vehicle roll angle response has been managed using adaptive sliding surface. This concept can be extended for other vehicle configurations. The proposed control scheme is investigated for efficacy using a full vehicle simulation model of CarSim software and National Highway Traffic Safety Administration’s proposed Fishhook maneuver. The controller is able to limit the rollover propensity even with vehicle parameter uncertainties.

  2. Effect of Foam Cladding for Blast Mitigation: Numerical Simulation

    Institute of Scientific and Technical Information of China (English)

    MA Guowei; YE Ziqing; ZHANG Xingui


    Two numerical simulations were performed to investigate the protective effect of the foam cladding.One simulation is based on a previous experimental study,which is a ballistic pendulum with and without a foam cladding subjected to close-range blast loading.The other model is a steel beam with and without a foam cladding under blast loading.The overpressure due to the blast event can be calculated by the empirical function ConWep or by an arbitrary Lagrangian-Eulerian (ALE)coupling model.The first approach is relatively simple and widely used.The second approach can model the propagation of the blast wave in the air and the interaction between the air and the solid.Itis found that the pendulum with the foam cladding always swings to a larger rotation angel compared to a bare pendulum.However,the steel beam with an appropriate foam cladding has a smaller deflection compared to the bare beam without a foam cladding.It is concluded that the protective effect of the foam cladding depends on the properties of the foam and the protected structure.

  3. Mitigating effects of salicylic acid against herbicidal stress

    Directory of Open Access Journals (Sweden)

    Singh N. B.


    Full Text Available Background, the context and purpose of the study: Pendimethalin [N-(1-ethyl propyl-2, 6-dinitro-3, 4 xylidine] is one of the most commonly used herbicides. It induces harmful effect on non-target plants besides controlling the weed emergence. Salicylic acid (SA plays an important role in abiotic stress tolerance. Present study was to assess the comparative efficacy of SA in combination with different concentrations of pendimethalin on black gram (Vigna mungo. The seeds of test plant were treated with field relevant concentrations (2, 5 and 10 ppm of pendimethalin (P and in combination with SA (0.5 mM to observe effect of SA against herbicide toxicity. Experiment was performed in petri dish as well as in pot culture. The toxic effect of pendimethalin and SA on seed germination (SG, radicle length (RL and mitotic index (MI was evaluated in petri dish culture. Seedling height, pigments, protein, sugar contents and lipid peroxidation (LP of 15 days old seedling were measured in pot culture. Total antioxidants (TA were monitored as plant defence against oxidative stress. Results, the main findings: Results showed that SG and seedling growth of Vigna mungo decreased under P1, P2 and P3 treatments. RL and MI were also reduced significantly (p<0.05 in treatments with herbicide and reduction was more pronounced in P3 treatment. A slight increase of SG and seedling growth was observed in P2 treatment compared to P1. Herbicide treatment remarkably declined pigment, protein and sugar contents of the seedlings when compared with control. TA and malondialdehyde (MDA content increase significantly under pendimethalin treated seedlings. Combined treatment (P+SA elevated growth of the seedlings. As a consequence of herbicidal stress, SA enhanced SG, RL, MI, pigment, protein and sugar content significantly. Under combined treatments,LP and TA were decreased when compared with pendimethalin treatment. Conclusions, brief summary and potential implications: SA

  4. Characterizing the Effects of Stormwater Mitigation on Nutrient Export and Stream Concentrations (United States)

    Bell, Colin D.; McMillan, Sara K.; Clinton, Sandra M.; Jefferson, Anne J.


    Urbanization increases nutrient loading and lowers residence times for processing of reactive solutes, including nitrate, total dissolved nitrogen, orthophosphate, and dissolved organic carbon), which leads to increased stream concentrations and mass export. Stormwater control measures mitigate the impacts of urbanization, and have the potential to improve stream water quality, however the net effect instream is not well understood. We monitored two urban and two suburban watersheds in Charlotte, NC to determine if mitigation controlled the fraction of total mass export during storm, if development classification as either urban or suburban (defined by the age, density and distribution of urban development) controlled storm nutrient and carbon dynamics, and if stormwater control measures were able to change stream water chemistry. While average concentrations during stormflow were generally greater than baseflow, indicating that storms are important times of solute export, the fraction of storm-derived export was unrelated to mitigation by stormwater control measures. Development classification was generally not an important control on export of N and dissolved organic carbon. However, event mean concentrations of orthophosphate were higher at the suburban sites, possibly from greater fertilizer application. Stormwater control measures influenced instream water chemistry at only one site, which also had the greatest mitigated area, but differences between stormwater control measure outflow and stream water suggest the potential for water quality improvements. Together, results suggest stormwater control measures have the potential to decrease solute concentrations from urban runoff, but the type, location, and extent of urban development in the watershed may influence the magnitude of this effect.

  5. Characterizing the Effects of Stormwater Mitigation on Nutrient Export and Stream Concentrations. (United States)

    Bell, Colin D; McMillan, Sara K; Clinton, Sandra M; Jefferson, Anne J


    Urbanization increases nutrient loading and lowers residence times for processing of reactive solutes, including nitrate, total dissolved nitrogen, orthophosphate, and dissolved organic carbon), which leads to increased stream concentrations and mass export. Stormwater control measures mitigate the impacts of urbanization, and have the potential to improve stream water quality, however the net effect instream is not well understood. We monitored two urban and two suburban watersheds in Charlotte, NC to determine if mitigation controlled the fraction of total mass export during storm, if development classification as either urban or suburban (defined by the age, density and distribution of urban development) controlled storm nutrient and carbon dynamics, and if stormwater control measures were able to change stream water chemistry. While average concentrations during stormflow were generally greater than baseflow, indicating that storms are important times of solute export, the fraction of storm-derived export was unrelated to mitigation by stormwater control measures. Development classification was generally not an important control on export of N and dissolved organic carbon. However, event mean concentrations of orthophosphate were higher at the suburban sites, possibly from greater fertilizer application. Stormwater control measures influenced instream water chemistry at only one site, which also had the greatest mitigated area, but differences between stormwater control measure outflow and stream water suggest the potential for water quality improvements. Together, results suggest stormwater control measures have the potential to decrease solute concentrations from urban runoff, but the type, location, and extent of urban development in the watershed may influence the magnitude of this effect.

  6. Mitigation Effect of Finite Larmor Radius on Rayleigh-Taylor Instability in Z-Pinch Implosions

    Institute of Scientific and Technical Information of China (English)

    邱孝明; 黄林; 简广德


    Based on the framework of magnetohydrodynamic theory, a simple model is proposed to study the mitigation effect of finite Larmor radius on the Rayleigh-Taylor instability in Z-pinch implosions. In this model, taking account of Ti ≥ Te in Z-pinch implosions we believe that the magnetohydrodynamic plasma responds to a perturbation (~ exp [i (k. x - ωt)]) at frequency (ω + ik2⊥ρ2iΩi) instead of frequency ω, where k2⊥ρ2i is due to the finite Larmor radius effects expressed from the generalkinetic theory of magnetized plasma. Therefore the linearized continuity and momentum equations for the perturbed mass-density and velocity include the finite Larmor radius effects. The calculations indicate that, in the wavenumber region of interest, the finite Larmor radius effects can mitigate the Rayleigh-Taylor instability in Z-pinch implosions.

  7. Cost-effective alternatives for mitigating Cryptosporidium risk in drinking water and enhancing ecosystem services (United States)

    Bryan, B. A.; Kandulu, J. M.


    Under the multibarrier paradigm, water quality management barriers that mitigate risk to consumers are required at multiple points from the catchment to the tap. We present a cost-effectiveness analysis of 13 catchment- and treatment-based management alternatives for mitigating Cryptosporidium risk in the Myponga water supply catchment, South Australia. A broad range of costs and benefits are identified and valued, including setup, operation and maintenance, and opportunity costs, and benefits for ecosystem services including water quality, biodiversity, carbon sequestration, and farm production services. The results suggest that the cost-effectiveness of investment in water quality management can be substantially enhanced by considering the costs of management and the benefits for ecosystem services, in addition to Cryptosporidium removal effectiveness. Cost-effectiveness of investment in management alternatives is dependent upon the desired level of Cryptosporidium removal effectiveness by both the catchment and treatment barriers. The combination of a spatially targeted 25% restriction in water course access of nondairy cattle and treatment by enhanced coagulation provides the most (net) cost-effective Cryptosporidium risk mitigation strategy. This combination may achieve 0.614 log removal at a net cost of A0.7 million and (net) cost-effectiveness of A1.14 million per log removal. Additional risk mitigation can be achieved through the addition of ultraviolet irradiation treatment, higher levels of water course access restriction for cattle, and the adoption of dung beetles in the catchment. Economic valuation of a range of costs and benefits of management priorities can support cost-effective water quality management investment decisions and inform elements of policy design such as cost-sharing arrangements and spatial targeting.

  8. Modeling the Effects of Harvest Alternatives on Mitigating Oak Decline in a Central Hardwood Forest Landscape.

    Directory of Open Access Journals (Sweden)

    Wen J Wang

    Full Text Available Oak decline is a process induced by complex interactions of predisposing factors, inciting factors, and contributing factors operating at tree, stand, and landscape scales. It has greatly altered species composition and stand structure in affected areas. Thinning, clearcutting, and group selection are widely adopted harvest alternatives for reducing forest vulnerability to oak decline by removing susceptible species and declining trees. However, the long-term, landscape-scale effects of these different harvest alternatives are not well studied because of the limited availability of experimental data. In this study, we applied a forest landscape model in combination with field studies to evaluate the effects of the three harvest alternatives on mitigating oak decline in a Central Hardwood Forest landscape. Results showed that the potential oak decline in high risk sites decreased strongly in the next five decades irrespective of harvest alternatives. This is because oak decline is a natural process and forest succession (e.g., high tree mortality resulting from intense competition would eventually lead to the decrease in oak decline in this area. However, forest harvesting did play a role in mitigating oak decline and the effectiveness varied among the three harvest alternatives. The group selection and clearcutting alternatives were most effective in mitigating oak decline in the short and medium terms, respectively. The long-term effects of the three harvest alternatives on mitigating oak decline became less discernible as the role of succession increased. The thinning alternative had the highest biomass retention over time, followed by the group selection and clearcutting alternatives. The group selection alternative that balanced treatment effects and retaining biomass was the most viable alternative for managing oak decline. Insights from this study may be useful in developing effective and informed forest harvesting plans for managing oak

  9. Modeling the Effects of Harvest Alternatives on Mitigating Oak Decline in a Central Hardwood Forest Landscape. (United States)

    Wang, Wen J; He, Hong S; Spetich, Martin A; Shifley, Stephen R; Thompson Iii, Frank R; Fraser, Jacob S


    Oak decline is a process induced by complex interactions of predisposing factors, inciting factors, and contributing factors operating at tree, stand, and landscape scales. It has greatly altered species composition and stand structure in affected areas. Thinning, clearcutting, and group selection are widely adopted harvest alternatives for reducing forest vulnerability to oak decline by removing susceptible species and declining trees. However, the long-term, landscape-scale effects of these different harvest alternatives are not well studied because of the limited availability of experimental data. In this study, we applied a forest landscape model in combination with field studies to evaluate the effects of the three harvest alternatives on mitigating oak decline in a Central Hardwood Forest landscape. Results showed that the potential oak decline in high risk sites decreased strongly in the next five decades irrespective of harvest alternatives. This is because oak decline is a natural process and forest succession (e.g., high tree mortality resulting from intense competition) would eventually lead to the decrease in oak decline in this area. However, forest harvesting did play a role in mitigating oak decline and the effectiveness varied among the three harvest alternatives. The group selection and clearcutting alternatives were most effective in mitigating oak decline in the short and medium terms, respectively. The long-term effects of the three harvest alternatives on mitigating oak decline became less discernible as the role of succession increased. The thinning alternative had the highest biomass retention over time, followed by the group selection and clearcutting alternatives. The group selection alternative that balanced treatment effects and retaining biomass was the most viable alternative for managing oak decline. Insights from this study may be useful in developing effective and informed forest harvesting plans for managing oak decline.

  10. Parents' experience of unintended childbearing: A qualitative study of factors that mitigate or exacerbate effects. (United States)

    Kavanaugh, Megan L; Kost, Kathryn; Frohwirth, Lori; Maddow-Zimet, Isaac; Gor, Vivian


    Births resulting from an unintended pregnancy affect individuals differentially, and some may experience more negative consequences than others. In this study, we sought to describe the mechanisms through which the severity of effects may be mitigated or exacerbated. We conducted in-depth interviews with 35 women and 30 men, all with a youngest child born resulting from an unintended pregnancy, in two urban sites in the United States. Respondents described both negative and positive effects of the child's birth in the areas of school; work and finances; partner relationships; personal health and outlook on life trajectories. Mechanisms through which unintended pregnancies mitigated or exacerbated certain effects fell at the individual (e.g. lifestyle modification), interpersonal (e.g. partner support) and structural (e.g. workplace flexibility) levels. These qualitative findings deepen understanding of the impact of unintended childbearing on the lives of women, men and families.

  11. Motion mitigation for lung cancer patients treated with active scanning proton therapy

    Energy Technology Data Exchange (ETDEWEB)

    Grassberger, Clemens, E-mail: [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 and Center for Proton Radiotherapy, Paul Scherrer Institute, Villigen-PSI 5232 (Switzerland); Dowdell, Stephen; Sharp, Greg; Paganetti, Harald [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 (United States)


    Purpose: Motion interplay can affect the tumor dose in scanned proton beam therapy. This study assesses the ability of rescanning and gating to mitigate interplay effects during lung treatments. Methods: The treatments of five lung cancer patients [48 Gy(RBE)/4fx] with varying tumor size (21.1–82.3 cm{sup 3}) and motion amplitude (2.9–30.6 mm) were simulated employing 4D Monte Carlo. The authors investigated two spot sizes (σ ∼ 12 and ∼3 mm), three rescanning techniques (layered, volumetric, breath-sampled volumetric) and respiratory gating with a 30% duty cycle. Results: For 4/5 patients, layered rescanning 6/2 times (for the small/large spot size) maintains equivalent uniform dose within the target >98% for a single fraction. Breath sampling the timing of rescanning is ∼2 times more effective than the same number of continuous rescans. Volumetric rescanning is sensitive to synchronization effects, which was observed in 3/5 patients, though not for layered rescanning. For the large spot size, rescanning compared favorably with gating in terms of time requirements, i.e., 2x-rescanning is on average a factor ∼2.6 faster than gating for this scenario. For the small spot size however, 6x-rescanning takes on average 65% longer compared to gating. Rescanning has no effect on normal lung V{sub 20} and mean lung dose (MLD), though it reduces the maximum lung dose by on average 6.9 ± 2.4/16.7 ± 12.2 Gy(RBE) for the large and small spot sizes, respectively. Gating leads to a similar reduction in maximum dose and additionally reduces V{sub 20} and MLD. Breath-sampled rescanning is most successful in reducing the maximum dose to the normal lung. Conclusions: Both rescanning (2–6 times, depending on the beam size) as well as gating was able to mitigate interplay effects in the target for 4/5 patients studied. Layered rescanning is superior to volumetric rescanning, as the latter suffers from synchronization effects in 3/5 patients studied. Gating minimizes the

  12. Application of super absorbent polymer and ascorbic acid to mitigate deleterious effects of cadmium in wheat


    Moghadam,Hamid Reza Tohidi


    ABSTRACT The growing use of chemical fertilizers, insecticides and pesticides can cause potential contamination with heavy metals to soil and groundwater, posing environmental and health threats. Heavy metals can also affect crop yield. A greenhouse experiment was conducted to explore the role of ascorbic acid foliar application and soil-applied super absorbent to mitigate adverse effects of cadmium (Cd), in terms of biochemical parameters in wheat. The experiment was installed in a completel...

  13. Preliminary Failure Modes and Effects Analysis of the US Massive Gas Injection Disruption Mitigation System Design

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader


    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a candidate design for the ITER Disruption Mitigation System. This candidate is the Massive Gas Injection System that provides machine protection in a plasma disruption event. The FMEA was quantified with “generic” component failure rate data as well as some data calculated from operating facilities, and the failure events were ranked for their criticality to system operation.

  14. Targeting the Renin–Angiotensin System Combined With an Antioxidant Is Highly Effective in Mitigating Radiation-Induced Lung Damage

    Energy Technology Data Exchange (ETDEWEB)

    Mahmood, Javed [Ontario Cancer Institute and the Campbell Family Institute for Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario (Canada); Radiation Medicine Program, STTARR Innovation Centre, Princess Margaret Cancer Centre, Toronto, Ontario (Canada); Jelveh, Salomeh [Radiation Medicine Program, STTARR Innovation Centre, Princess Margaret Cancer Centre, Toronto, Ontario (Canada); Zaidi, Asif [Ontario Cancer Institute and the Campbell Family Institute for Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario (Canada); Doctrow, Susan R. [Pulmonary Center, Department of Medicine, Boston University, Boston, Massachusetts (United States); Medhora, Meetha [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Hill, Richard P., E-mail: [Ontario Cancer Institute and the Campbell Family Institute for Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario (Canada); Departments of Medical Biophysics and Radiation Oncology, University of Toronto, Toronto, Ontario (Canada)


    Purpose: To investigate the outcome of suppression of the renin angiotensin system using captopril combined with an antioxidant (Eukarion [EUK]-207) for mitigation of radiation-induced lung damage in rats. Methods and Materials: The thoracic cavity of female Sprague-Dawley rats was irradiated with a single dose of 11 Gy. Treatment with captopril at a dose of 40 mg/kg/d in drinking water and EUK-207 given by subcutaneous injection (8 mg/kg daily) was started 1 week after irradiation (PI) and continuing until 14 weeks PI. Breathing rate was monitored until the rats were killed at 32 weeks PI, when lung fibrosis was assessed by lung hydroxyproline content. Lung levels of the cytokine transforming growth factor-β1 and macrophage activation were analyzed by immunohistochemistry. Oxidative DNA damage was assessed by 8-hydroxy-2-deoxyguanosine levels, and lipid peroxidation was measured by a T-BARS assay. Results: The increase in breathing rate in the irradiated rats was significantly reduced by the drug treatments. The drug treatment also significantly decreased the hydroxyproline content, 8-hydroxy-2-deoxyguanosine and malondialdehyde levels, and levels of activated macrophages and the cytokine transforming growth factor-β1 at 32 weeks. Almost complete mitigation of these radiation effects was observed by combining captopril and EUK-207. Conclusion: Captopril and EUK-207 can provide mitigation of radiation-induced lung damage out to at least 32 weeks PI after treatment given 1-14 weeks PI. Overall the combination of captopril and EUK-207 was more effective than the individual drugs used alone.

  15. Mitigating amphibian chytridiomycosis with bioaugmentation: characteristics of effective probiotics and strategies for their selection and use. (United States)

    Bletz, Molly C; Loudon, Andrew H; Becker, Matthew H; Bell, Sara C; Woodhams, Douglas C; Minbiole, Kevin P C; Harris, Reid N


    Probiotic therapy through bioaugmentation is a feasible disease mitigation strategy based on growing evidence that microbes contribute to host defences of plants and animals. Amphibians are currently threatened by the rapid global spread of the pathogen, Batrachochytrium dendrobatidis (Bd), which causes the disease chytridiomycosis. Bioaugmentation of locally occurring protective bacteria on amphibians has mitigated this disease effectively in laboratory trials and one recent field trial. Areas still naïve to Bd provide an opportunity for conservationists to proactively implement probiotic strategies to prevent further amphibian declines. In areas where Bd is endemic, bioaugmentation can facilitate repatriation of susceptible amphibians currently maintained in assurance colonies. Here, we synthesise the current research in amphibian microbial ecology and bioaugmentation to identify characteristics of effective probiotics in relation to their interactions with Bd, their host, other resident microbes and the environment. To target at-risk species and amphibian communities, we develop sampling strategies and filtering protocols that result in probiotics that inhibit Bd under ecologically relevant conditions and persist on susceptible amphibians. This filtering tool can be used proactively to guide amphibian disease mitigation and can be extended to other taxa threatened by emerging infectious diseases.

  16. Increased temperature mitigates the effects of ocean acidification in calcified green algae ( Halimeda spp.) (United States)

    Campbell, Justin E.; Fisch, Jay; Langdon, Chris; Paul, Valerie J.


    The singular and interactive effects of ocean acidification and temperature on the physiology of calcified green algae ( Halimeda incrassata, H. opuntia, and H. simulans) were investigated in a fully factorial, 4-week mesocosm experiment. Individual aquaria replicated treatment combinations of two pH levels (7.6 and 8.0) and two temperatures (28 and 31 °C). Rates of photosynthesis, respiration, and calcification were measured for all species both prior to and after treatment exposure. Pre-treatment measurements revealed that H. incrassata displayed higher biomass-normalized rates of photosynthesis and calcification (by 55 and 81 %, respectively) relative to H. simulans and H. opuntia. Furthermore, prior to treatment exposure, photosynthesis was positively correlated to calcification, suggesting that the latter process may be controlled by photosynthetic activity in this group. After treatment exposure, net photosynthesis was unaltered by pH, yet significantly increased with elevated temperature by 58, 38, and 37 % for H. incrassata, H. simulans, and H. opuntia, respectively. Both pH and temperature influenced calcification, but in opposing directions. On average, calcification declined by 41 % in response to pH reduction, but increased by 49 % in response to elevated temperature. Within each pH treatment, elevated temperature increased calcification by 23 % (at pH 8.0) and 74 % (at pH 7.6). Interactions between pH, temperature, and/or species were not observed. This work demonstrates that, in contrast to prior studies, increased temperature may serve to enhance the metabolic performance (photosynthesis and calcification) of some marine calcifiers, despite elevated carbon dioxide concentrations. Thus, in certain cases, ocean warming may mitigate the negative effects of acidification.

  17. Final Report 02-ERD-056 Active Load Control& Mitigation Using Microtabs: A Wind Energy Application

    Energy Technology Data Exchange (ETDEWEB)

    Nakafuji, D Y


    With public concern over the security and reliability of our existing electricity infrastructure and the resurgence of wind energy, the wind industry offers an immediate, first point of entry for the application and demonstration of an active load control technology. An innovative microtab approach is being investigated and demonstrated for active aerodynamic load control applications under the mid-year LDRD (June-Sept. 2002) effort. With many of these million dollar turbines failing at only half the design lifespans, conventional techniques for stiffening rotors, enlarging generators and gearboxes, and reinforcing towers are insufficient to accommodate the demands for bigger, taller and more powerful turbines. The DOE through the National Renewable Energy Laboratory (NREL) supports R&D efforts to develop lighter, more efficient and longer lasting wind turbines and advance turbine components. However, as wind turbine systems continue to increase in size and complexity, fundamental research and technology development has not kept pace with needs. New technologies to increase turbine life spans and to reduce costs are needed to realize wind electricity generation potentials. It is becoming quite evident that without a better understanding of static and dynamic response to normal and abnormal operating loads coupled with sophisticated flow analysis and control techniques, large turbine operating life and component life will be severely limited. Promising technologies include active load control and load alleviation systems to mitigate peak loads from damaging key components. This project addresses science and engineering challenges of developing enabling technologies for active load control for turbine applications using an innovative, translational microtab approach. Figure 1.1 illustrates the microtabs as applied on a wind turbine system. Extending wind turbine operating life is a crucial component for reducing the cost of wind-generated electricity, enabling wind

  18. The effectiveness of cool and green roofs as urban heat island mitigation strategies (United States)

    Li, Dan; Bou-Zeid, Elie; Oppenheimer, Michael


    Mitigation of the urban heat island (UHI) effect at the city-scale is investigated using the Weather Research and Forecasting (WRF) model in conjunction with the Princeton Urban Canopy Model (PUCM). Specifically, the cooling impacts of green roof and cool (white/high-albedo) roof strategies over the Baltimore-Washington metropolitan area during a heat wave period (7 June-10 June 2008) are assessed using the optimal set-up of WRF-PUCM described in the companion paper by Li and Bou-Zeid (2014). Results indicate that the surface UHI effect (defined based on the urban-rural surface temperature difference) is reduced significantly more than the near-surface UHI effect (defined based on urban-rural 2 m air temperature difference) when these mitigation strategies are adopted. In addition, as the green and cool roof fractions increase, the surface and near-surface UHIs are reduced almost linearly. Green roofs with relatively abundant soil moisture have comparable effect in reducing the surface and near-surface UHIs to cool roofs with an albedo value of 0.7. Significant indirect effects are also observed for both green and cool roof strategies; mainly, the low-level advection of atmospheric moisture from rural areas into urban terrain is enhanced when the fraction of these roofs increases, thus increasing the humidity in urban areas. The additional benefits or penalties associated with modifications of the main physical determinants of green or cool roof performance are also investigated. For green roofs, when the soil moisture is increased by irrigation, additional cooling effect is obtained, especially when the ‘unmanaged’ soil moisture is low. The effects of changing the albedo of cool roofs are also substantial. These results also underline the capabilities of the WRF-PUCM framework to support detailed analysis and diagnosis of the UHI phenomenon, and of its different mitigation strategies.

  19. Strategies, Protections and Mitigations for Electric Grid from Electromagnetic Pulse Effects

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Rita Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); Frickey, Steven Jay [Idaho National Lab. (INL), Idaho Falls, ID (United States)


    The mission of DOE’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electricity delivery system, enhance the security and reliability of America’s energy infrastructure and facilitate recovery from disruptions to the energy supply. One of the threats OE is concerned about is a high-altitude electro-magnetic pulse (HEMP) from a nuclear explosion and eletro-magnetic pulse (EMP) or E1 pulse can be generated by EMP weapons. DOE-OE provides federal leadership and technical guidance in addressing electric grid issues. The Idaho National Laboratory (INL) was chosen to conduct the EMP study for DOE-OE due to its capabilities and experience in setting up EMP experiments on the electric grid and conducting vulnerability assessments and developing innovative technology to increase infrastructure resiliency. This report identifies known impacts to EMP threats, known mitigations and effectiveness of mitigations, potential cost of mitigation, areas for government and private partnerships in protecting the electric grid to EMP, and identifying gaps in our knowledge and protection strategies.

  20. PRESS40: a project for involving students in active seismic risk mitigation (United States)

    Barnaba, Carla; Contessi, Elisa; Rosa Girardi, Maria


    To memorialize the anniversary of the 1976 Friuli earthquake, the Istituto Statale di Istruzione Superiore "Magrini Marchetti" in Gemona del Friuli (NE Italy), with the collaboration of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS), has promoted the PRESS40 Project (Prevenzione Sismica nella Scuola a 40 anni dal terremoto del Friuli, that in English sounds like "Seismic Prevention at School 40 years later the Friuli earthquake"). The project has developed in the 2015-2016 school year, starting from the 40th anniversary of the Friuli earthquake, and it aims to disseminate historical memory, seismic culture and awareness of seismic safety in the young generations, too often unconscious of past experiences, as recent seismic hazard perception tests have demonstrated. The basic idea of the PRESS40 Project is to involve the students in experimental activities to be active part of the seismic mitigation process. The Project is divided into two main parts, the first one in which students learn-receive knowledge from researchers, and the second one in which they teach-bring knowledge to younger students. In the first part of the project, 75 students of the "Magrini Marchetti" school acquired new geophysical data, covering the 23 municipalities from which they come from. These municipalities represent a wide area affected by the 1976 Friuli earthquake. In each locality a significant site was examined, represented by a school area. At least, 127 measurements of ambient noise have been acquired. Data processing and interpretation of all the results are still going on, under the supervision of OGS researchers.The second part of the project is planned for the early spring, when the students will present the results of geophysical survey to the younger ones of the monitored schools and to the citizens in occasion of events to commemorate the 40th anniversary of the Friuli earthquake.

  1. Recent advances in understanding and mitigating adipogenic and metabolic effects of antipsychotic drugs

    Directory of Open Access Journals (Sweden)

    Julia M Gohlke


    Full Text Available Although offering many benefits for several psychiatric disorders, antipsychotic drugs (APDs as a class have a major liability in their tendency to promote adiposity, obesity, and metabolic dysregulation in an already metabolically vulnerable population. The past decade has witnessed substantial research aimed at investigating the mechanisms of these adverse effects and mitigating them. On July 11 and 12, 2011, with support from 2 NIH institutes, leading experts convened to discuss current research findings and to consider future research strategies. Five areas where significant advances are being made emerged from the conference: (1 methodological issues in the study of APD effects; (2 unique characteristics and needs of pediatric patients; (3 genetic components underlying susceptibility to APD-induced metabolic effects; (4 APD effects on weight gain and adiposity in relation to their acute effects on glucose regulation and diabetes risk; and (5 the utility of behavioral, dietary, and pharmacological interventions in mitigating APD-induced metabolic side effects. This paper summarizes the major conclusions and important supporting data from the meeting.

  2. Submerged macrophytes mitigate direct and indirect insecticide effects in freshwater communities.

    Directory of Open Access Journals (Sweden)

    William R Brogan

    Full Text Available Understanding how ecological interactions mitigate the impacts of perturbations such as pesticides in biological communities is an important basic and applied question for ecologists. In aquatic ecosystems, new evidence from microcosm experiments suggests that submerged macrophytes can buffer cladocerans from pulse exposures to the widely used insecticide malathion, and that mitigation increases with macrophyte density. However, whether these results scale up to more complex aquatic communities where ecological interactions such as competition can alter toxicity is unknown. Further, macrophyte abilities to mitigate different insecticide exposure scenarios (i.e. single versus repeated pulses have never been tested. To address these gaps, we performed a factorial mesocosm experiment examining the influence of four macrophyte treatments (0, 10, 50, or 100 Elodea Canadensis shoots planted per mesocosm crossed with three malathion exposure scenarios (no insecticide, single pulse, repeated pulses on aquatic communities containing zooplankton, phytoplankton, periphyton, two snail species, and larval amphibians. In the absence of macrophytes, single malathion pulses caused short-term declines in cladoceran abundance followed by their rapid recovery, which precluded any indirect effects (i.e. trophic cascades. However, repeated malathion pulses caused cladoceran extinctions, resulting in persistent phytoplankton blooms and reduced abundance of one snail species. In contrast, with macrophytes present, even at low density, malathion had no effect on any taxa. We also discovered novel effects of macrophytes on the benthic food web. In the two highest macrophyte treatments, we observed trends of reduced periphyton biomass, decreased abundance of one snail species, and decreased amphibian time to and mass at metamorphosis. To our knowledge, this is the first evidence of negative submerged macrophyte effects on amphibians, a taxa of global conservation concern

  3. Mitigation of microtiter plate positioning effects using a block randomization scheme. (United States)

    Roselle, Christopher; Verch, Thorsten; Shank-Retzlaff, Mary


    Microtiter plate-based assays are a common tool in biochemical and analytical labs. Despite widespread use, results generated in microtiter plate-based assays are often impacted by positional bias, in which variability in raw signal measurements are not uniform in all regions of the plate. Since small positional effects can disproportionately affect assay results and the reliability of the data, an effective mitigation strategy is critical. Commonly used mitigation strategies include avoiding the use of outer regions of the plate, replicating treatments within and between plates, and randomizing placement of treatments within and between plates. These strategies often introduce complexity while only partially mitigating positional effects and significantly reducing assay throughput. To reduce positional bias more effectively, we developed a novel block-randomized plate layout. Unlike a completely randomized layout, the block randomization scheme coordinates placement of specific curve regions into pre-defined blocks on the plate based on key experimental findings and assumptions about the distribution of assay bias and variability. Using the block-randomized plate layout, we demonstrated a mean bias reduction of relative potency estimates from 6.3 to 1.1 % in a sandwich enzyme-linked immunosorbent assay (ELISA) used for vaccine release. In addition, imprecision in relative potency estimates decreased from 10.2 to 4.5 % CV. Using simulations, we also demonstrated the impact of assay bias on measurement confidence and its relation to replication strategies. We outlined the underlying concepts of the block randomization scheme to potentially apply to other microtiter-based assays.

  4. Mitigation of charged impurity effects in graphene field-effect transistors with polar organic molecules (Presentation Recording) (United States)

    Worley, Barrett C.; Kim, Seohee; Akinwande, Deji; Rossky, Peter J.; Dodabalapur, Ananth


    Recent developments in monolayer graphene production allow its use as the active layer in field-effect transistor technology. Favorable electrical characteristics of monolayer graphene include high mobility, operating frequency, and good stability. These characteristics are governed by such key transport physical phenomena as electron-hole transport symmetry, Dirac point voltage, and charged impurity effects. Doping of graphene occurs during device fabrication, and is largely due to charged impurities located at or near the graphene/substrate interface. These impurities cause scattering of charge carriers, which lowers mobility. Such scattering is detrimental to graphene transistor performance, but our group has shown that coating with fluoropolymer thin films or exposure to polar organic vapors can restore favorable electrical characteristics to monolayer graphene. By partially neutralizing charged impurities and defects, we can improve the mobility by approximately a factor of 2, change the Dirac voltage by fairly large amounts, and reduce the residual carrier density significantly. We hypothesize that this phenomena results from screening of charged impurities by the polar molecules. To better understand such screening interactions, we performed computational chemistry experiments to observe interactions between polar organic molecules and monolayer graphene. The molecules interacted more strongly with defective graphene than with pristine graphene, and the electronic environment of graphene was altered. These computational observations correlate well with our experimental results to support our hypothesis that polar molecules can act to screen charged impurities on or near monolayer graphene. Such screening favorably mitigates charge scattering, improving graphene transistor performance.

  5. High-Performance Laser Peening for Effective Mitigation of Stress Corrosion Cracking

    Energy Technology Data Exchange (ETDEWEB)

    Hackel, L; Hao-Lin, C; Wong, F; Hill, M


    Stress corrosion cracking (SCC) in the Yucca Mountain waste package closure welds is believed to be the greatest threat to long-term containment. Use of stress mitigation to eliminate tensile stresses resulting from welding can prevent SCC. A laser technology with sufficient average power to achieve high throughput has been developed and commercially deployed with high peak power and sufficiently high average power to be an effective laser peening system. An appropriately applied version of this process could be applied to eliminate SCC in the waste package closure welds.

  6. Mitigation of Radiation and EMI Effects on the Vacuum Control System of LHC

    CERN Document Server

    Pigny, G; Krakowski, P; Rio, B


    The 26 km of vacuum chambers where circulates the beam of the Large Hadron Collider (LHC) must be maintained under Ultra High Vacuum (UHV) to minimize the beam interactions with residual gases, and allow the operation of specific systems. The vacuum level is measured by several thousands of gauges along the accelerator. Bad vacuum quality may trigger a beam dump and close the associated sector valves. The effects of radiation or Electromagnetic Interferences (EMI) on components that may stop the machine must be evaluated and minimized. We report on the actions implemented to mitigate their impact on the vacuum control system.

  7. Modeling and simulation of induction motor drive system to investigate and mitigate of PWM inverter' s adverse effects

    Institute of Scientific and Technical Information of China (English)

    ESMAELI Abdolreza; SUN Li


    Modeling and simulation of induction motor drive system to investigate and mitigate the adverse effects of PWM inverter based on analysis, modeling and simulation are presented. The estimation of conducted disturbances and other adverse effects of PWM inverter by simulation offer a considerable gain from the economic point of view. For an accurate model of the motor drive system including mains, rectifier, inverter, motor and its long cables, the high frequency parasitic current paths are taken into account. The novel model and its parasitic values for three-phase induction motor system are presented. Finally a new solution for suppressing EMI, common mode voltage, leakage current, bearing current and shaft voltages is proposed and the results show the excellent performances of proposed solution including active and passive filters.

  8. Effectiveness of Space Debris Mitigation Guidelines: Economic Potential of LEO and Traffic Management Issues (United States)

    Belviso, Luciano

    Space debris probably represent one of the major issues for the future development and exploitation of space by all spacefaring nations. Considering the large range of possible mitigation techniques, some general criteria to evaluate them shall be taken into account: cost, effectiveness, technical and legal applicability in order to assess their effectiveness. Even though the Inter Agency Space Debris Coordination Committee (IADC) guidelines are considered as the basis for a new regulatory regime of mitigation, the problem concerning the legal instrument by which the international community would accept these guidelines remains still unsolved. In this paper, we will focus on the following issues: Economic potential of orbital regions. Since the international community lacks consensus to conclude a legally binding instrument, a voluntary adherence regime seems a possible way to apply mitigation measures. However, with mitigation efforts having only small effects into the future, expenditures are not easy to be justified today even if they could reduce the economic consequences of debris in the long period[1]. Some orbital regions, such as the Geostationary Orbit, are already the subject of international agreements, however, the properties of other regions of near-earth space are also distinct as far as their potential economic value is concerned[2]. Therefore, the applicability of mitigation techniques on the basis of cost-benefit analysis will be considered in this paper. Applicability of satellites traffic control. For satellites in Low Earth Orbit, the main hazard is posed by other object located in narrow sets of altitudes and inclinations[4]. Satellites control systems usually allow only a limited number of operation mostly related to small trajectory corrections and they can result not sufficient to avoid collisions with debris. That is why a complementary approach is required although this could represent an additional cost. In this paper we will consider the

  9. Cost-effectiveness analysis of policy instruments for greenhouse gas emission mitigation in the agricultural sector. (United States)

    Bakam, Innocent; Balana, Bedru Babulo; Matthews, Robin


    Market-based policy instruments to reduce greenhouse gas (GHG) emissions are generally considered more appropriate than command and control tools. However, the omission of transaction costs from policy evaluations and decision-making processes may result in inefficiency in public resource allocation and sub-optimal policy choices and outcomes. This paper aims to assess the relative cost-effectiveness of market-based GHG mitigation policy instruments in the agricultural sector by incorporating transaction costs. Assuming that farmers' responses to mitigation policies are economically rationale, an individual-based model is developed to study the relative performances of an emission tax, a nitrogen fertilizer tax, and a carbon trading scheme using farm data from the Scottish farm account survey (FAS) and emissions and transaction cost data from literature metadata survey. Model simulations show that none of the three schemes could be considered the most cost effective in all circumstances. The cost effectiveness depends both on the tax rate and the amount of free permits allocated to farmers. However, the emissions trading scheme appears to outperform both other policies in realistic scenarios.

  10. Effective mitigation of debris flows at Lemon Dam, La Plata County, Colorado (United States)

    deWolfe, Victor G.; Santi, Paul M.; Ey, J.; Gartner, Joseph E.


    To reduce the hazards from debris flows in drainage basins burned by wildfire, erosion control measures such as construction of check dams, installation of log erosion barriers (LEBs), and spreading of straw mulch and seed are common practice. After the 2002 Missionary Ridge Fire in southwest Colorado, these measures were implemented at Knight Canyon above Lemon Dam to protect the intake structures of the dam from being filled with sediment. Hillslope erosion protection measures included LEBs at concentrations of 220-620/ha (200-600% of typical densities), straw mulch was hand spread at concentrations up to 5.6 metric tons/hectare (125% of typical densities), and seeds were hand spread at 67-84 kg/ha (150% of typical values). The mulch was carefully crimped into the soil to keep it in place. In addition, 13 check dams and 3 debris racks were installed in the main drainage channel of the basin. The technical literature shows that each mitigation method working alone, or improperly constructed or applied, was inconsistent in its ability to reduce erosion and sedimentation. At Lemon Dam, however, these methods were effective in virtually eliminating sedimentation into the reservoir, which can be attributed to a number of factors: the density of application of each mitigation method, the enhancement of methods working in concert, the quality of installation, and rehabilitation of mitigation features to extend their useful life. The check dams effectively trapped the sediment mobilized during rainstorms, and only a few cubic meters of debris traveled downchannel, where it was intercepted by debris racks. Using a debris volume-prediction model developed for use in burned basins in the Western U.S., recorded rainfall events following the Missionary Ridge Fire should have produced a debris flow of approximately 10,000 m 3 at Knight Canyon. The mitigation measures, therefore, reduced the debris volume by several orders of magnitude. For comparison, rainstorm-induced debris

  11. Effective mitigation of debris flows at Lemon Dam, La Plata County, Colorado (United States)

    deWolfe, V.G.; Santi, P.M.; Ey, J.; Gartner, J.E.


    To reduce the hazards from debris flows in drainage basins burned by wildfire, erosion control measures such as construction of check dams, installation of log erosion barriers (LEBs), and spreading of straw mulch and seed are common practice. After the 2002 Missionary Ridge Fire in southwest Colorado, these measures were implemented at Knight Canyon above Lemon Dam to protect the intake structures of the dam from being filled with sediment. Hillslope erosion protection measures included LEBs at concentrations of 220-620/ha (200-600% of typical densities), straw mulch was hand spread at concentrations up to 5.6??metric tons/hectare (125% of typical densities), and seeds were hand spread at 67-84??kg/ha (150% of typical values). The mulch was carefully crimped into the soil to keep it in place. In addition, 13 check dams and 3 debris racks were installed in the main drainage channel of the basin. The technical literature shows that each mitigation method working alone, or improperly constructed or applied, was inconsistent in its ability to reduce erosion and sedimentation. At Lemon Dam, however, these methods were effective in virtually eliminating sedimentation into the reservoir, which can be attributed to a number of factors: the density of application of each mitigation method, the enhancement of methods working in concert, the quality of installation, and rehabilitation of mitigation features to extend their useful life. The check dams effectively trapped the sediment mobilized during rainstorms, and only a few cubic meters of debris traveled downchannel, where it was intercepted by debris racks. Using a debris volume-prediction model developed for use in burned basins in the Western U.S., recorded rainfall events following the Missionary Ridge Fire should have produced a debris flow of approximately 10,000??m3 at Knight Canyon. The mitigation measures, therefore, reduced the debris volume by several orders of magnitude. For comparison, rainstorm

  12. Simulating Urban Tree Effects on Air, Water, and Heat Pollution Mitigation: iTree-Hydro Model (United States)

    Yang, Y.; Endreny, T. A.; Nowak, D.


    Urban and suburban development changes land surface thermal, radiative, porous, and roughness properties and pollutant loading rates, with the combined effect leading to increased air, water, and heat pollution (e.g., urban heat islands). In this research we present the USDA Forest Service urban forest ecosystem and hydrology model, iTree Eco and Hydro, used to analyze how tree cover can deliver valuable ecosystem services to mitigate air, water, and heat pollution. Air pollution mitigation is simulated by dry deposition processes based on detected pollutant levels for CO, NO2, SO2, O3 and atmospheric stability and leaf area indices. Water quality mitigation is simulated with event mean concentration loading algorithms for N, P, metals, and TSS, and by green infrastructure pollutant filtering algorithms that consider flow path dispersal areas. Urban cooling considers direct shading and indirect evapotranspiration. Spatially distributed estimates of hourly tree evapotranspiration during the growing season are used to estimate human thermal comfort. Two main factors regulating evapotranspiration are soil moisture and canopy radiation. Spatial variation of soil moisture is represented by a modified urban topographic index and radiation for each tree is modified by considering aspect, slope and shade from surrounding buildings or hills. We compare the urban cooling algorithms used in iTree-Hydro with the urban canopy and land surface physics schemes used in the Weather Research and Forecasting model. We conclude by identifying biophysical feedbacks between tree-modulated air and water quality environmental services and how these may respond to urban heating and cooling. Improvements to this iTree model are intended to assist managers identify valuable tree services for urban living.


    Directory of Open Access Journals (Sweden)

    J. C. MOREKI


    Full Text Available This paper explores the effects of climate change on dairy production in Botswana and mitigation strategies are suggested. Dairy farming has not experienced growth over time rendering the country heavily dependent on milk imports. National dairy herd is estimated to be approximately 5000 and per capita consumption of milk about 32.5 litres per person per year. Currently, Botswana is experiencing average high temperatures and low rainfall, frequent droughts and scarcity of both ground and surface water, which all contribute to low livestock and crop productivity. Changes in rainfall patterns, frequent droughts, high incidences of animal diseases (e.g., mastitis and FMD and parasites, and high environmental temperatures cause significant decrease in livestock productivity. For dairy animals, there is a decline in milk yield and reduced animal weight gain due mainly to high temperatures and inadequate feeds. Mitigation strategies comprise using smaller dairy breeds such as Jersey and Brown Swiss and local Tswana breed, growing fodder crops and utilization of crop residues and constructing cow sheds. Thus, the effects of climate change on dairy cattle production are real and require immediate attention if they are to be minimized or managed properly to attain higher milk production.

  14. Automation bias: a systematic review of frequency, effect mediators, and mitigators. (United States)

    Goddard, Kate; Roudsari, Abdul; Wyatt, Jeremy C


    Automation bias (AB)--the tendency to over-rely on automation--has been studied in various academic fields. Clinical decision support systems (CDSS) aim to benefit the clinical decision-making process. Although most research shows overall improved performance with use, there is often a failure to recognize the new errors that CDSS can introduce. With a focus on healthcare, a systematic review of the literature from a variety of research fields has been carried out, assessing the frequency and severity of AB, the effect mediators, and interventions potentially mitigating this effect. This is discussed alongside automation-induced complacency, or insufficient monitoring of automation output. A mix of subject specific and freetext terms around the themes of automation, human-automation interaction, and task performance and error were used to search article databases. Of 13 821 retrieved papers, 74 met the inclusion criteria. User factors such as cognitive style, decision support systems (DSS), and task specific experience mediated AB, as did attitudinal driving factors such as trust and confidence. Environmental mediators included workload, task complexity, and time constraint, which pressurized cognitive resources. Mitigators of AB included implementation factors such as training and emphasizing user accountability, and DSS design factors such as the position of advice on the screen, updated confidence levels attached to DSS output, and the provision of information versus recommendation. By uncovering the mechanisms by which AB operates, this review aims to help optimize the clinical decision-making process for CDSS developers and healthcare practitioners.

  15. Mitigation of drought negative effect on ecosystem productivity by vegetation mixing (United States)

    Van den Hoof, Catherine; Lambert, Fabrice


    Vegetation diversity and interaction is thought to have a beneficial effect on ecosystem functioning, particularly improving ecosystem resistance to drought. This is of significant importance in the context of a warmer world, as extreme events such as droughts become more likely. Most of the studies performed so far on vegetation interaction are based on observations. Here we use the land surface model JULES to study the potential of vegetation mixing to mitigate the negative effect of drought events on the land surface through interaction, a mechanism which is difficult to study in situ at large scales. Using a set of simulations with mixed and unmixed vegetation, we show that the carbon, water, and energy fluxes are significantly affected by vegetation competition for water resources. The interaction is in general beneficial for the ecosystem carbon assimilation due to a better use of water resources. This benefit is highest when traits between vegetation types concerning resource competition overlap least. For a tree-grass combination, mixing improves carbon assimilation by 5% to 8% during summer. The benefit of mixing increases further under progressively more resource-limited conditions up to an inflection point with a benefit of 14%, after which it falls back to zero under extremely dry conditions. Mixing also tends to reduce the interannual variability of the ecosystem carbon sink and therefore improves the resistance of the ecosystem. Our results highlight the importance of vegetation interaction in climate simulations and impact studies and the potential of vegetation mixing as a mitigation tool.

  16. The Effectiveness of the Regulatory Regime for Black Carbon Mitigation in the Arctic

    Directory of Open Access Journals (Sweden)

    Daria Shapovalova


    Full Text Available In addition to being a hazardous air pollutant, Black Carbon is the second-largest contributor to Arctic warming. Its mitigation is being addressed at the international regulatory level by the Arctic Council and the Convention on Long-Range Transboundary Air Pollution (CLRTAP. Whilst the Convention and its protocols are binding documents, the Black Carbon regulation under their framework appears to have ‘soft law’ characteristics. At the same time, the voluntary Black Carbon and Methane Framework, adopted by the Arctic Council, demonstrates positive compliance and follow-up dynamics compared to earlier norm-creating attempts. This paper argues that the nature of the norm (binding or non-binding is not the decisive factor regarding effective implementation in the Arctic region. Current efforts to mitigate Black Carbon by means of a non-binding Arctic Council Black Carbon and Methane Framework represent an improvement in the Council's normative function and may have more effect on the behaviour of Arctic States than relevant provisions under the Gothenburg Protocol to the CLRTAP. To support this argument, the first section presents an overview of the Arctic Council as an actor in Arctic policy-making. It then provides an assessment of current efforts to combat Black Carbon carried out by the Arctic Council and the CLRTAP.

  17. Secondary effects of urban heat island mitigation measures on air quality (United States)

    Fallmann, Joachim; Forkel, Renate; Emeis, Stefan


    This study presents numerical simulations analysing the effect of urban heat island (UHI) mitigation measures on the chemical composition of the urban atmosphere. The mesoscale chemical transport model WRF-Chem is used to investigate the impact of urban greening and highly reflective surfaces on the concentrations of primary (CO, NO) as well as secondary pollutants (O3) inside the urban canopy. In order to account for the sub-grid scale heterogeneity of urban areas, a multi-layer urban canopy model is coupled to WRF-Chem. Using this canopy model at its full extend requires the introduction of several urban land use classes in WRF-Chem. The urban area of Stuttgart serves as a test bed for the modelling of a case scenario of the 2003 European Heat Wave. The selected mitigation measures are able to reduce the urban temperature by about 1 K and the mean ozone concentration by 5-8%. Model results however document also negative secondary effects on urban air quality, which are closely related to a decrease of vertical mixing in the urban boundary layer. An increase of primary pollutants NO and CO by 5-25% can be observed. In addition, highly reflective surfaces can increase peak ozone concentration by up to 12% due to a high intensity of reflected shortwave radiation accelerating photochemical reactions.

  18. Skin effect mitigation in laser processed multi-walled carbon nanotube/copper conductors

    Energy Technology Data Exchange (ETDEWEB)

    Keramatnejad, K.; Zhou, Y. S.; Gao, Y.; Rabiee Golgir, H.; Wang, M.; Lu, Y. F., E-mail: [Department of Electrical and Computer Engineering, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0511 (United States); Jiang, L. [School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100081 (China); Silvain, J.-F. [Institut de Chimie de la Matière Condensée de Bordeaux (ICMCB-CNRS) 87, Avenue du Docteur Albert Schweitzer F-33608 Pessac Cedex (France)


    In this study, laser-processed multi-walled carbon nanotube (MWCNT)/Cu conductors are introduced as potential passive components to mitigate the skin effect of Cu at high frequencies (0–10 MHz). Suppressed skin effect is observed in the MWCNT/Cu conductors compared to primitive Cu. At an AC frequency of 10 MHz, a maximum AC resistance reduction of 94% was observed in a MWCNT/Cu conductor after being irradiated at a laser power density of 189 W/cm{sup 2}. The reduced skin effect in the MWCNT/Cu conductors is ascribed to the presence of MWCNT channels which are insensitive to AC frequencies. The laser irradiation process is observed to play a crucial role in reducing contact resistance at the MWCNT-Cu interfaces, removing impurities in MWCNTs, and densifying MWCNT films.

  19. Impact and mitigation of space weather effects on GNSS receiver performance (United States)

    Sreeja, V.


    It is well known that Global Navigation Satellite System (GNSS) signals suffer from a number of vulnerabilities, out of which a potential severe vulnerability is the effect of space weather. Space weather effects on the signals transmitted by GNSS include the effect of ionospheric perturbations and solar radio bursts. Intense solar radio bursts occurring in the L-band can impact the tracking performance of GNSS receivers located in the sunlit hemisphere of the Earth and are therefore a potential threat to safety-critical systems based on GNSS. Consequently monitoring these events is important for suitable warnings to be issued in support to related services and applications. On the other hand, the space weather effects leading to ionospheric perturbations on the GNSS signals are either due to dispersion or scintillation caused by plasma density irregularities. Scintillation can cause cycle slips and degrade the positioning accuracy in GNSS receivers. The high-latitude scintillation occurrence is known to correlate with changes in the solar and interplanetary conditions along with a consequential impact on GNSS receiver tracking performance. An assessment of the GNSS receiver tracking performance under scintillation can be analysed through the construction of receiver phase-locked loop (PLL) tracking jitter maps. These maps can offer a potentially useful tool to provide users with the prevailing tracking conditions under scintillation over a certain area and also be used to help mitigate the effects of scintillation on GNSS positioning. This paper reviews some of recent research results related to the impact and mitigation of space weather effects on GNSS receiver performance.

  20. Adaptation of business activities to the requirements of climate change mitigation - Case carrier bags; Liiketoiminnan sopeuttaminen ilmastonmuutoksen hillinnaen vaatimuksiin (OPTIKASSI)

    Energy Technology Data Exchange (ETDEWEB)

    Dahlbo, H.; Mattila, T.; Korhonen, M.-R.; Myllymaa, T. (Finnish Environment Institute SYKE, Helsinki (Finland)); Soukka, R. (Lappeenranta Univ. of Technology, Department of Energy and Environmental Technology (Finland)); Kujanpaeae, M. (KCL Science and Consulting, Espoo (Finland))


    Shopping bags have been a prominent topic of debate lately. Many countries have banned disposable bags or imposed a tax on them. The motives have been to avoid littering, reduce reliance on oil, and curb climate change. Restrictions are also justified by the accumulation of plastic garbage in the oceans, and by the damage to marine organisms. The environmental effects of production, use, and disposal of shopping bags are small compared with other consumption. However, the choice of a shopping bag is repeated every week, and the consumer is not sure about the consequences of each alternative. To reduce this uncertainty the OPTIKASSI study was made. The study called 'Adaptation of business activities to the requirements of climate change mitigation . case shopping bags, OPTIKASSI project' was implemented to study shopping bag alternatives in Finnish grocery stores, and the effects of the bags on climate change and the possibilities to mitigate them. Finnish Environment Institute and Lappeenranta University of Technology were responsible for the study, funded by Tekes ClimBus Programme, and the bag producers Suominen Flexible Packaging Ltd, Plastiroll Oy (Ltd), UPM-Kymmene LtdWisapaper and CabassiOy. The goal of the OPTIKASSI project was to compile lifecycle based information about the climate effects of the most typical shopping bags. It was also desirable to find the best consumption and waste management solutions for bags made of various materials. Products compared were plastic bags of virgin material, and of recycled material, paper bags, canvas bags, and shopping bags of biodegradable plastic. According to the results the shopping bags are an insignificant part of the climate effects of a Finnish household, but negligent use of bags may multiply the effects. Based on scenario, sensitivity, and ambiguity studies: garbage bags should be replaced by plastic bags, and the bins packed full and tight, incineration is not sensible; paper bags should be

  1. Does Climate Change Mitigation Activity Affect Crude Oil Prices? Evidence from Dynamic Panel Model

    Directory of Open Access Journals (Sweden)

    Jude C. Dike


    Full Text Available This paper empirically investigates how climate change mitigation affects crude oil prices while using carbon intensity as the indicator for climate change mitigation. The relationship between crude oil prices and carbon intensity is estimated using an Arellano and Bond GMM dynamic panel model. This study undertakes a regional-level analysis because of the geographical similarities among the countries in a region. Regions considered for the study are Africa, Asia and Oceania, Central and South America, the EU, the Middle East, and North America. Results show that there is a positive relationship between crude oil prices and carbon intensity, and a 1% change in carbon intensity is expected to cause about 1.6% change in crude oil prices in the short run and 8.4% change in crude oil prices in the long run while the speed of adjustment is 19%.

  2. Assessing the Impact of Active Land Management in Mitigating Wildfire Threat to Source Water Supply Quality (United States)

    Bladon, K. D.; Silins, U.; Emelko, M. B.; Flannigan, M.; Dupont, D.; Robinne, F.; Wang, X.; Parisien, M. A.; Stone, M.; Thompson, D. K.; Tymstra, C.; Schroeder, D.; Kienzle, S. W.; Anderson, A.


    The vast majority of surface water supplies in Alberta originates in forested regions of the province, and supports approximately 94 municipal utilities, 208 communities, and 67% of the provincial population. These surface water supplies are highly vulnerable to contamination inputs and changing water conditions associated with wildfires. A provincial scale risk analysis framework is being used to investigate the magnitude and likelihood of wildfire occurrence in source water regions to evaluate the potential for altered water quality and quantity. The initial analysis identified which forested regions and which municipal drinking water treatment facilities are most at risk from wildfire. The efficacy of several current and potential landscape treatments to mitigate wildfire threats, along with the likely outcome of these treatments on mitigation of potential impacts of wildfire to drinking water treatment, are being modeled. A Monte Carlo modeling approach incorporating wildfire regime characteristics is used to simulate the ignition and growth of wildfires and generate outcome distributions for the different mitigation strategies. Cumulative changes in water quality at large river basin scales are being modeled and linked to water treatment impacts with the Soil and Water Assessment Tool (SWAT). A critical foundation of this approach is the close interaction of a large, trans-disciplinary team of researchers capable of integrating highly diverse issues of landscape wildfire dynamics, cross-scale water supply issues, and their linkage to downstream risks to drinking water treatment engineering.

  3. Mitigating the effect of noise in the hybrid input-output method of phase retrieval. (United States)

    Trahan, Russell; Hyland, David


    Here a modification to the hybrid input-output (HIO) method of phase retrieval is presented which aides in mitigating the negative effects of low signal-to-noise ratios (SNRs). Various type of interferometers measure diffraction patterns which are used to determine the Fourier transform modulus of an objective. Interferometry often suffers from very low SNRs making phase retrieval difficult because of the sensitivity of most phase retrieval algorithms to local minima. Here we analyze the effect of noise on the HIO method. The result is used as a rationale for the proposed modification to the HIO method. The algorithm presented here introduces a filtering scheme which removes much of the Fourier modulus noise. Examples are shown and the results are compared to the HIO method with and without the proposed modification. Comparisons are also made to other methods of filtering the Fourier modulus noise.

  4. Modelling and mitigating refractive propagation effects in precision pulsar timing observations

    CERN Document Server

    Shannon, R M


    To obtain the most accurate pulse arrival times from radio pulsars, it is necessary to correct or mitigate the effects of the propagation of radio waves through the warm and ionised interstellar medium. We examine both the strength of propagation effects associated with large-scale electron-density variations and the methodology used to estimate infinite-frequency arrival times. Using simulations of two-dimensional phase-varying screens, we assess the strength and non-stationarity of timing perturbations associated with large-scale density variations. We identify additional contributions to arrival times that are stochastic in both radio frequency and time and therefore not amenable to correction solely using times of arrival. We attribute this to the frequency dependence of the trajectories of the propagating radio waves. We find that this limits the efficacy of low-frequency (metre-wavelength) observations. Incorporating low-frequency pulsar observations into precision timing campaigns is increasingly probl...

  5. Vitamin D mitigates the adverse effects of obesity on breast cancer in mice. (United States)

    Swami, Srilatha; Krishnan, Aruna V; Williams, Jasmaine; Aggarwal, Abhishek; Albertelli, Megan A; Horst, Ronald L; Feldman, Brian J; Feldman, David


    Obesity is an established risk factor for postmenopausal breast cancer (BCa), insulin resistance, and vitamin D deficiency, and all contribute to increased synthesis of mammary estrogens, the drivers of estrogen receptor-positive (ER+) BCa growth. As both dietary vitamin D and calcitriol treatments inhibit breast estrogen synthesis and signaling, we hypothesized that vitamin D would be especially beneficial in mitigating the adverse effects of obesity on ER+BCa. To assess whether obesity exerted adverse effects on BCa growth and whether vitamin D compounds could reduce these unfavorable effects, we employed a diet-induced obesity (DIO) model in ovariectomized C57BL/6 mice. Breast tumor cells originally from syngeneic Mmtv-Wnt1 transgenic mice were then implanted into the mammary fat pads of lean and obese mice. DIO accelerated the initiation and progression of the mammary tumors. Treatments with either calcitriol or dietary vitamin D reduced the adverse effects of obesity causing a delay in tumor appearance and inhibiting continued tumor growth. Beneficial actions of treatments with vitamin D or calcitriol on BCa and surrounding adipose tissue included repressed Esr1, aromatase, and Cox2 expression; decreased tumor-derived estrogen and PGE2; reduced expression of leptin receptors; and increased adiponectin receptors. We demonstrate that vitamin D treatments decreased insulin resistance, reduced leptin, and increased adiponectin signaling and also regulated the LKB1/AMPK pathway contributing to an overall decrease in local estrogen synthesis in the obese mice. We conclude that calcitriol and dietary vitamin D, acting by multiple interrelated pathways, mitigate obesity-enhanced BCa growth in a postmenopausal setting.

  6. Modeling effects of urban heat island mitigation strategies on heat-related morbidity: a case study for Phoenix, Arizona, USA. (United States)

    Silva, Humberto R; Phelan, Patrick E; Golden, Jay S


    A zero-dimensional energy balance model was previously developed to serve as a user-friendly mitigation tool for practitioners seeking to study the urban heat island (UHI) effect. Accordingly, this established model is applied here to show the relative effects of four common mitigation strategies: increasing the overall (1) emissivity, (2) percentage of vegetated area, (3) thermal conductivity, and (4) albedo of the urban environment in a series of percentage increases by 5, 10, 15, and 20% from baseline values. In addition to modeling mitigation strategies, we present how the model can be utilized to evaluate human health vulnerability from excessive heat-related events, based on heat-related emergency service data from 2002 to 2006. The 24-h average heat index is shown to have the greatest correlation to heat-related emergency calls in the Phoenix (Arizona, USA) metropolitan region. The four modeled UHI mitigation strategies, taken in combination, would lead to a 48% reduction in annual heat-related emergency service calls, where increasing the albedo is the single most effective UHI mitigation strategy.

  7. Space Charge effects and mitigation in the CERN PS Booster, in view of the Upgrade

    CERN Document Server

    Benedetto, Elena; Forte, Vincenzo; Schmidt, Frank


    The CERN PS Booster (PSB) is presently running with a space charge tune spread larger than 0.5 at injection. Since the High Luminosity LHC (HL-LHC) will require beams with twice the intensity and brightness of today, the LHC Injector Upgrade (LIU) Project is putting in place an upgrade program for all the injector chain and, in particular, it relies on the important assumption that the PS Booster can successfully produce these beams after the implementation of the 160 MeV H- injection from Linac4. This contribution describes the studies (measure-ments and simulations) that have been carried out to con- firm that the PSB can indeed perform as needed in terms of beam brightness for the future HL-LHC runs. The importance of the mitigation measures already in place, such as the correction of the half-integer line, and the effects of non-linear resonances on the beam are also discussed.

  8. Mitigation of nonlinear transmission effects for OFDM 16-QAM optical signal using adaptive modulation. (United States)

    Skidin, Anton S; Sidelnikov, Oleg S; Fedoruk, Mikhail P; Turitsyn, Sergei K


    The impact of the fiber Kerr effect on error statistics in the nonlinear (high power) transmission of the OFDM 16-QAM signal over a 2000 km EDFA-based link is examined. We observed and quantified the difference in the error statistics for constellation points located at three power-defined rings. Theoretical analysis of a trade-off between redundancy and error rate reduction using probabilistic coding of three constellation power rings decreasing the symbol-error rate of OFDM 16-QAM signal is presented. Based on this analysis, we propose to mitigate the nonlinear impairments using the adaptive modulation technique applied to the OFDM 16-QAM signal. We demonstrate through numerical modelling the system performance improvement by the adaptive modulation for the large number of OFDM subcarriers (more than 100). We also show that a similar technique can be applied to single carrier transmission.

  9. What land covers are effective in mitigating a heat island in urban building rooftop? (United States)

    Lee, S.; Ryu, Y.


    Since the 20th century, due to the rapid urbanization many urban environment problems have got blossomed and above all heat island has been recognized as an important issue. There are several causes of urban heat island, but land cover change occupies the largest portion of them. Owing to urban expansion, vegetation is changed into asphalt pavements and concrete buildings, which reduces latent heat flux. To mitigate the problems, people enlarge vegetation covers such as planting street trees, making rooftop gardens and constructing parks or install white roofs that feature high albedo on a building. While the white roofs reflect about 70% of solar radiation and absorb less radiation, vegetation has low albedo but cools the air through transpiration and fixes carbon dioxide through photosynthesis. There are some studies concerning which one is more effective to mitigate heat island between the green roof and white roof. This study compares the green roof and white roof and additionally considers carbon fixation that has not been treated in other studies. Furthermore, this study ascertains an efficiency of solar-cell panel that is used for building roof recently. The panel produces electric power but has low albedo which could warm the air. The experiment is conducted at the rooftop in Seoul, Korea and compares green roof (grass), white roof (painted cover), black roof (solar panel) and normal painted roof. Surface temperature and albedo are observed for the four roof types and incoming shortwave, outgoing longwave and carbon flux are measured in green roof solely. In the case of solar panels, the electricity generation is calculated from the incoming radiation. We compute global warming potentials for the four roof types and test which roof type is most effective in reducing global warming potential.

  10. Assessing and Mitigating the Effects of Windblown Soil on Rare and Common Vegetation (United States)

    Gleason, Sean M.; Faucette, Dave T.; Toyofuku, Mai M.; Torres, Carlos A.; Bagley, Calvin F.


    Acting under the auspices of the US Endangered Species Act, we quantified wind erosion and its effects on rare and common plant species on a semi-arid military installation in Hawaii. Our goal was to develop management strategies, based on local data, to aid the conservation of rare and common indigenous plants and their habitats. We collected windblown soil coming off of roads and other disturbed soils to assess likely impacts to plants occurring at certain heights and distances from disturbed surfaces. We then subjected plants in a glasshouse to windblown dust treatments, designed from our field data to simulate erosion events, and evaluated the effect of these treatments on photosynthesis and survival. We also designed several field experiments to examine the in-situ effects of windblown soil and soil substrate on germination, growth rate, and survival of indigenous and nonindigenous plants. We conclude from these experiments that most direct effects of windblown soil to plants can be effectively mitigated by locating roads and training areas at least 40 m from sensitive plant habitats and through vegetation management to maintain at least 11% aerial cover on disturbed surfaces. Effects of soil type on germination, growth, and survival was species-specific, emphasizing the importance of species trials prior to, or during, rehabilitation efforts.

  11. Large-scale assessment of flood risk and the effects of mitigation measures along the Elbe River

    NARCIS (Netherlands)

    Kok, de J.L.; Grossmann, M.


    The downstream effects of flood risk mitigation measures and the necessity to develop flood risk management strategies that are effective on a basin scale call for a flood risk assessment methodology that can be applied at the scale of a large river. We present an example of a rapid flood risk asses

  12. Effects of Evapotranspiration on Mitigation of Urban Temperature by Vegetation and Urban Agriculture

    Institute of Scientific and Technical Information of China (English)

    QIU Guo-yu; LI Hong-yong; ZHANG Qing-tao; CHEN Wan; LIANG Xiao-jian; LI Xiang-ze


    The temperature difference between an urban space and surrounding non-urban space is called the urban heat island effect (UHI). Global terrestrial evapotranspiration (ET) can consume 1.4803×1023 joules (J) of energy annually, which is about 21.74%of the total available solar energy at the top of atmosphere, whereas annual human energy use is 4.935×1020 J, about 0.33%of annual ET energy consumption. Vegetation ET has great potential to reduce urban and global temperatures. Our literature review suggests that vegetation and urban agricultural ET can reduce urban temperatures by 0.5 to 4.0°C. Green roofs (including urban agriculture) and water bodies have also been shown to be effective ways of reducing urban temperatures. The cooling effects on the ambient temperature and the roof surface temperature can be 0.24-4.0°C and 0.8-60.0°C, respectively. The temperature of a water body (including urban aquaculture) can be lower than the temperature of the surrounding built environment by between 2 and 6°C, and a water body with a 16 m2 surface area can cool up to 2 826 m3 of nearby space by 1°C. Based on these findings, it can be concluded that the increase of evapotranspiration in cities, derived from vegetation, urban agriculture, and water body, can effectively mitigate the effect of urban heat islands.

  13. Shunt hybrid active power filter for harmonic mitigation: A practical design approach

    Indian Academy of Sciences (India)

    Unnikrishnan A K; Chandira Sekaran E; Subhash Joshi T G; Manju A S; Aby Joseph


    The increasing importance of Power Quality problems has been responsible for several improvements in Active Power Filter (APF) typologies in the last decade. The increased cost and switching losses make a pure shunt APF economically impractical for high power applications. In higher power levels shunt Hybrid Active Power Filter (HAPF) has been reported to be a useful approach to eliminate current harmonics caused by nonlinear loads. This paper presents a control strategy and design criteria for transformer-less shunt HAPF with special attention to the integration of series passive filter. The paper also compares the performance improvement of passive harmonic filter when modified as shunt HAPF. Experimental results obtained verify the viability and effectiveness of the proposed design criteria and control algorithm.

  14. Effectiveness of protected areas in mitigating fire within their boundaries: case study of Chiapas, Mexico. (United States)

    Román-Cuesta, María Rosa; Martínez-Vilalta, Jordi


    Since the severe 1982-1983 El Niño drought, recurrent burning has been reported inside tropical protected areas (TPAs). Despite the key role of fire in habitat degradation, little is known about the effectiveness of TPAs in mitigating fire incidence and burned areas. We used a GPS fire database (1995-2005) (n=3590 forest fires) obtained from the National Forest Commission to compare fire incidence (number of fires) and burned areas inside TPAs and their surrounding adjacent buffer areas in Southern Mexico (Chiapas). Burned areas inside parks ranged from 2% (Palenque) to 45% (Lagunas de Montebello) of a park's area, and the amount burned was influenced by two severe El Niño events (1998 and 2003). These two years together resulted in 67% and 46% of the total area burned in TPAs and buffers, respectively during the period under analysis. Larger burned areas in TPAs than in their buffers were exclusively related to the extent of natural habitats (flammable area excluding agrarian and pasture lands). Higher fuel loads together with access and extinction difficulties were likely behind this trend. A higher incidence of fire in TPAs than in their buffers was exclusively related to anthropogenic factors such as higher road densities and agrarian extensions. Our results suggest that TPAs are failing to mitigate fire impacts, with both fire incidence and total burned areas being significantly higher in the reserves than in adjacent buffer areas. Management plans should consider those factors that facilitate fires in TPAs: anthropogenic origin of fires, sensitivity of TPAs to El Niñio-droughts, large fuel loads and fuel continuity inside parks, and limited financial resources. Consideration of these factors favors lines of action such as alternatives to the use of fire (e.g., mucuna-maize system), climatic prediction to follow the evolution of El Niño, fuel management strategies that favor extinction practices, and the strengthening of local communities and ecotourism.

  15. Afforestation to mitigate climate change: impacts on food prices under consideration of albedo effects (United States)

    Kreidenweis, Ulrich; Humpenöder, Florian; Stevanović, Miodrag; Bodirsky, Benjamin Leon; Kriegler, Elmar; Lotze-Campen, Hermann; Popp, Alexander


    Ambitious climate targets, such as the 2 °C target, are likely to require the removal of carbon dioxide from the atmosphere. Afforestation is one such mitigation option but could, through the competition for land, also lead to food prices hikes. In addition, afforestation often decreases land-surface albedo and the amount of short-wave radiation reflected back to space, which results in a warming effect. In particular in the boreal zone, such biophysical warming effects following from afforestation are estimated to offset the cooling effect from carbon sequestration. We assessed the food price response of afforestation, and considered the albedo effect with scenarios in which afforestation was restricted to certain latitudinal zones. In our study, afforestation was incentivized by a globally uniform reward for carbon uptake in the terrestrial biosphere. This resulted in large-scale afforestation (2580 Mha globally) and substantial carbon sequestration (860 GtCO2) up to the end of the century. However, it was also associated with an increase in food prices of about 80% by 2050 and a more than fourfold increase by 2100. When afforestation was restricted to the tropics the food price response was substantially reduced, while still almost 60% cumulative carbon sequestration was achieved. In the medium term, the increase in prices was then lower than the increase in income underlying our scenario projections. Moreover, our results indicate that more liberalised trade in agricultural commodities could buffer the food price increases following from afforestation in tropical regions.

  16. Is the deleterious effect of cryotherapy on proprioception mitigated by exercise? (United States)

    Ribeiro, F; Moreira, S; Neto, J; Oliveira, J


    This study aimed to examine the acute effects of cryotherapy on knee position sense and to determine the time period necessary to normalize joint position sense when exercising after cryotherapy. 12 subjects visited the laboratory twice, once for cryotherapy followed by 30 min of exercise on a cycloergometer and once for cryotherapy followed by 30 min of rest. Sessions were randomly determined and separated by 48 h. Cryotherapy was applied in the form of ice bag, filled with 1 kg of crushed ice, for 20 min. Knee position sense was measured at baseline, after cryotherapy and every 5 min after cryotherapy removal until a total of 30 min. The main effect of cryotherapy was significant showing an increase in absolute (F7,154=43.76, pcryotherapy. The intervention after cryotherapy (rest vs. exercise) revealed a significant main effect only for absolute error (F7,154=4.05, pcryotherapy, the proprioceptive acuity reached the baseline values faster (10 min vs. 15 min). Our results indicated that the deleterious effect of cryotherapy on proprioception is mitigated by low intensity exercise, being the time necessary to normalize knee position sense reduced from 15 to 10 min.

  17. Consumer cost effectiveness of CO2 mitigation policies in restructured electricity markets (United States)

    Moore, Jared; Apt, Jay


    We examine the cost of carbon dioxide mitigation to consumers in restructured USA markets under two policy instruments, a carbon price and a renewable portfolio standard (RPS). To estimate the effect of policies on market clearing prices, we constructed hourly economic dispatch models of the generators in PJM and in ERCOT. We find that the cost effectiveness of policies for consumers is strongly dependent on the price of natural gas and on the characteristics of the generators in the dispatch stack. If gas prices are low (˜4/MMBTU), a technology-agnostic, rational consumer seeking to minimize costs would prefer a carbon price over an RPS in both regions. Expensive gas (˜7/MMBTU) requires a high carbon price to induce fuel switching and this leads to wealth transfers from consumers to low carbon producers. The RPS may be more cost effective for consumers because the added energy supply lowers market clearing prices and reduces CO2 emissions. We find that both policies have consequences in capacity markets and that the RPS can be more cost effective than a carbon price under certain circumstances: continued excess supply of capacity, retention of nuclear generators, and high natural gas prices.

  18. Mitigation of Electromagnetic Pulse (EMP) Effects from Short-Pulse Lasers and Fusion Neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Eder, D C; Throop, A; Brown, Jr., C G; Kimbrough, J; Stowell, M L; White, D A; Song, P; Back, N; MacPhee, A; Chen, H; DeHope, W; Ping, Y; Maddox, B; Lister, J; Pratt, G; Ma, T; Tsui, Y; Perkins, M; O' Brien, D; Patel, P


    Our research focused on obtaining a fundamental understanding of the source and properties of EMP at the Titan PW(petawatt)-class laser facility. The project was motivated by data loss and damage to components due to EMP, which can limit diagnostic techniques that can be used reliably at short-pulse PW-class laser facilities. Our measurements of the electromagnetic fields, using a variety of probes, provide information on the strength, time duration, and frequency dependence of the EMP. We measure electric field strengths in the 100's of kV/m range, durations up to 100 ns, and very broad frequency response extending out to 5 GHz and possibly beyond. This information is being used to design shielding to mitigate the effects of EMP on components at various laser facilities. We showed the need for well-shielded cables and oscilloscopes to obtain high quality data. Significant work was invested in data analysis techniques to process this data. This work is now being transferred to data analysis procedures for the EMP diagnostics being fielded on the National Ignition Facility (NIF). In addition to electromagnetic field measurements, we measured the spatial and energy distribution of electrons escaping from targets. This information is used as input into the 3D electromagnetic code, EMSolve, which calculates time dependent electromagnetic fields. The simulation results compare reasonably well with data for both the strength and broad frequency bandwidth of the EMP. This modeling work required significant improvements in EMSolve to model the fields in the Titan chamber generated by electrons escaping the target. During dedicated Titan shots, we studied the effects of varying laser energy, target size, and pulse duration on EMP properties. We also studied the effect of surrounding the target with a thick conducting sphere and cube as a potential mitigation approach. System generated EMP (SGEMP) in coaxial cables does not appear to be a significant at Titan. Our

  19. In vitro Screening of Essential Oil Active Compounds for Manipulation of Rumen Fermentation and Methane Mitigation. (United States)

    Joch, M; Cermak, L; Hakl, J; Hucko, B; Duskova, D; Marounek, M


    The objective of this study was to investigate the effects of 11 active compounds of essential oils (ACEO) on rumen fermentation characteristics and methane production. Two trials were conducted. In trial 1, ACEO (eugenol, carvacrol, citral, limonene, 1,4-cineole, p-cymene, linalool, bornyl acetate, α-pinene, and β-pinene) at a dose of 1,000 μL/L were incubated for 24 h in diluted rumen fluid with a 70:30 forage:concentrate substrate (16.2% crude protein; 36.6% neutral detergent fiber). Three fistulated Holstein cows were used as donors of rumen fluid. The reduction in methane production was observed with nine ACEO (up to 86% reduction) compared with the control (pproduction, and only bornyl acetate produced less methane per mol of VFA compared with the control (pproduction of two concentrations (500 and 2,000 μL/L) of bornyl acetate, the most promising ACEO from the first trial, were evaluated using the same in vitro incubation method that was used in the first trial. In trial 2, monensin was used as a positive control. Both doses of bornyl acetate decreased (pproduction and did not inhibit VFA production. Positive effects of bornyl acetate on methane and VFA production were more pronounced than the effects of monensin. These results confirm the ability of bornyl acetate to decrease methane production, which may help to improve the efficiency of energy use in the rumen.

  20. Mitigation of adverse effects on competitiveness and leakage of unilateral EU climate policy: An assessment of policy instruments

    NARCIS (Netherlands)

    Antimiani, A.; Costantini, V.; Kuik, O.J.; Paglialunga, E.


    The European Union (EU) has developed a strategy to mitigate climate change by cutting greenhouse gas (GHG) emissions and fostering low carbon technologies. However, the risk of implementing unilateral policies is that distortive effects are generated at the global scale affecting world energy price

  1. DAC to Mitigate the Effect of Periodic Disturbances on Drive Train using Collective Pitch for Variable Speed Wind Turbine

    DEFF Research Database (Denmark)

    Imran, Raja Muhammad; Hussain, Dil Muhammad Akbar; Soltani, Mohsen


    DAC is a linear control technique used to mitigate the effect of disturbance on the plant. It is a superposition of full state feedback and disturbance feedback. This paper presents a control technique based on Disturbance Accommodation Control (DAC) to reduce fatigue on drive train generated by ...

  2. Importance of biophysical effects on climate warming mitigation potential of biofuel crops over the conterminous United Sta (United States)

    Current quantification of Climate Warming Mitigation Potential (CWMP) of biomass-derived energy has focused primarily on its biogeochemical effects. This study used site-level observations of carbon, water, and energy fluxes of biofuel crops to parameterize and evaluate the Community Land Model (CLM...

  3. The Mitigating Effect of Citrullus colocynthis (L. Fruit Extract against Genotoxicity Induced by Cyclophosphamide in Mice Bone Marrow Cells

    Directory of Open Access Journals (Sweden)

    Mohammad Shokrzadeh


    Full Text Available Possible genoprotective effect of Citrullus colocynthis (L. (CCT fruits extract against cyclophosphamide- (CP-induced DNA damage in mice bone marrow cells was evaluated using micronucleus assay, as an index of induced chromosomal damage. Mice were preadministered with different doses of CCT via intraperitoneal injection for 7 consecutive days followed by injection with CP (70 mg/kg b.w. 1 hr after the last injection of CCT. After 24 hr, mice were scarified to evaluate the frequency of micronucleated polychromatic erythrocytes (MnPCEs. In addition, the number of polychromatic erythrocytes (PCEs among 1000 normochromatic erythrocytes (NCEs per animal was recorded to evaluate bone marrow. Pretreatment with CCT significantly reduced the number of MnPCEs induced by CP in bone marrow cells (P<0.0001. At 200 mg/kg, CCT had a maximum chemoprotective effect and reduced the number of MnPCEs by 6.37-fold and completely normalized the mitotic activity. CCT also led to marked proliferation and hypercellularity of immature myeloid elements after mice were treated with CP and mitigated the bone marrow suppression. Our study revealed that CCT has an antigenotoxic effect against CP-induced oxidative DNA damage in mice. Therefore, it could be used concomitantly as a supplement to protect people undergoing chemotherapy.

  4. Selecting optimal parallel microchannel configurations for active hot spot mitigation of multicore microprocessors in real time

    CERN Document Server

    Maganti, Lakshmi Sirisha; Sundararajan, T; Das, Sarit K


    Design of effective micro cooling systems to address the challenges of ever increasing heat flux from microdevices requires deep examination of real time problems and has been tackled in depth. The most common and apparently misleading assumption while designing micro cooling systems is that the heat flux generated by the device is uniform, but the reality is far from this. Detailed simulations have been performed by considering non uniform heat load employing the configurations U, I, Z for parallel microchannel systems with water and nanofluids as the coolants. An Intel Core i7 4770 3.40 GHz quad core processor has been mimicked using heat load data retrieved from a real microprocessor with non-uniform core activity. The study clearly demonstrates that there is a non-uniform thermal load induced temperature maldistribution along with the already existent flow maldistribution induced temperature maldistribution. The suitable configuration(s) for maximum possible overall heat removal for a hot zone while maxim...

  5. Modelling and mitigating refractive propagation effects in precision pulsar timing observations (United States)

    Shannon, R. M.; Cordes, J. M.


    To obtain the most accurate pulse arrival times from radio pulsars, it is necessary to correct or mitigate the effects of the propagation of radio waves through the warm and ionized interstellar medium. We examine both the strength of propagation effects associated with large-scale electron-density variations and the methodology used to estimate infinite frequency arrival times. Using simulations of two-dimensional phase-varying screens, we assess the strength and non-stationarity of timing perturbations associated with large-scale density variations. We identify additional contributions to arrival times that are stochastic in both radio frequency and time and therefore not amenable to correction solely using times of arrival. We attribute this to the frequency dependence of the trajectories of the propagating radio waves. We find that this limits the efficacy of low-frequency (metre-wavelength) observations. Incorporating low-frequency pulsar observations into precision timing campaigns is increasingly problematic for pulsars with larger dispersion measures.

  6. Equal graph partitioning on estimated infection network as an effective epidemic mitigation measure.

    Directory of Open Access Journals (Sweden)

    Jeremy Hadidjojo

    Full Text Available Controlling severe outbreaks remains the most important problem in infectious disease area. With time, this problem will only become more severe as population density in urban centers grows. Social interactions play a very important role in determining how infectious diseases spread, and organization of people along social lines gives rise to non-spatial networks in which the infections spread. Infection networks are different for diseases with different transmission modes, but are likely to be identical or highly similar for diseases that spread the same way. Hence, infection networks estimated from common infections can be useful to contain epidemics of a more severe disease with the same transmission mode. Here we present a proof-of-concept study demonstrating the effectiveness of epidemic mitigation based on such estimated infection networks. We first generate artificial social networks of different sizes and average degrees, but with roughly the same clustering characteristic. We then start SIR epidemics on these networks, censor the simulated incidences, and use them to reconstruct the infection network. We then efficiently fragment the estimated network by removing the smallest number of nodes identified by a graph partitioning algorithm. Finally, we demonstrate the effectiveness of this targeted strategy, by comparing it against traditional untargeted strategies, in slowing down and reducing the size of advancing epidemics.

  7. Functional diversity of catch mitigates negative effects of temperature variability on fisheries yields. (United States)

    Dee, Laura E; Miller, Steve J; Peavey, Lindsey E; Bradley, Darcy; Gentry, Rebecca R; Startz, Richard; Gaines, Steven D; Lester, Sarah E


    Temperature variation within a year can impact biological processes driving population abundances. The implications for the ecosystem services these populations provide, including food production from marine fisheries, are poorly understood. Whether and how temperature variability impacts fishery yields may depend on the number of harvested species and differences in their responses to varying temperatures. Drawing from previous theoretical and empirical studies, we predict that greater temperature variability within years will reduce yields, but harvesting a larger number of species, especially a more functionally diverse set, will decrease this impact. Using a global marine fisheries dataset, we find that within-year temperature variability reduces yields, but current levels of functional diversity (FD) of targeted species, measured using traits related to species' responses to temperature, largely offset this effect. Globally, high FD of catch could avoid annual losses in yield of 6.8% relative to projections if FD were degraded to the lowest level observed in the data. By contrast, species richness in the catch and in the ecosystem did not provide a similar mitigating effect. This work provides novel empirical evidence that short-term temperature variability can negatively impact the provisioning of ecosystem services, but that FD can buffer these negative impacts.

  8. Mitigating the Effects of Climate Change on the Water Resources of the Columbia River Basin

    Energy Technology Data Exchange (ETDEWEB)

    Payne, J.T.; Wood, A.W.; Hamlet, A.F.; Palmer, R.N.; Lettenmaier, D.P. [Department of Civil Engineering, 164 Wilcox Hall, P.O. Box 352700, University of Washington, Seattle, WA 98195-2700 (United States)


    The potential effects of climate change on the hydrology and water resources of the Columbia River Basin (CRB) were evaluated using simulations from the U.S. Department of Energy and National Center for Atmospheric Research Parallel Climate Model (DOE/NCAR PCM). This study focuses on three climate projections for the 21st century based on a 'business as usual' (BAU) global emissions scenario, evaluated with respect to a control climate scenario based on static 1995 emissions. Time-varying monthly PCM temperature and precipitation changes were statistically downscaled and temporally disaggregated to produce daily forcings that drove a macro-scale hydrologic simulation model of the Columbia River basin at 1/4-degree spatial resolution. For comparison with the direct statistical downscaling approach, a dynamical downscaling approach using a regional climate model (RCM) was also used to derive hydrologic model forcings for 20-year subsets from the PCM control climate (1995-2015) scenario and from the three BAU climate (2040-2060) projections. The statistically downscaled PCM scenario results were assessed for three analysis periods (denoted Periods 1-3: 2010-2039, 2040-2069, 2070-2098) in which changes in annual average temperature were +0.5, +1.3 and +2.1C, respectively, while critical winter season precipitation changes were -3, +5 and +1 percent. For RCM, the predicted temperature change for the 2040-2060 period was +1.2C and the average winter precipitation change was -3 percent, relative to the RCM control climate. Due to the modest changes in winter precipitation, temperature changes dominated the simulated hydrologic effects by reducing winter snow accumulation, thus shifting summer streamflow to the winter. The hydrologic changes caused increased competition for reservoir storage between firm hydropower and instream flow targets developed pursuant to the Endangered Species Act listing of Columbia River salmonids. We examined several alternative

  9. Assessing uncertainty in the cost-effectiveness of agricultural greenhouse gas mitigation


    Eory, Vera; Topp, Cairistiona F.E.; Moran, Dominic; Butler, Adam


    Information on the uncertainty of quantitative results feeding into public decision making is essential for designing robust policies. However, this information is often not available in relation to the economics of greenhouse gas (GHG) mitigation in agriculture. This paper analyses the uncertainty of the mitigation estimates provided by a Marginal Abatement Cost Curve (MACC). The case study is based on the GHG MACC developed for Scottish agricultural soils. The qualitative assessment disenta...

  10. Mitigation win-win (United States)

    Moran, Dominic; Lucas, Amanda; Barnes, Andrew


    Win-win messages regarding climate change mitigation policies in agriculture tend to oversimplify farmer motivation. Contributions from psychology, cultural evolution and behavioural economics should help to design more effective policy.

  11. Soil Moisture Active Passive (SMAP) Microwave Radiometer Radio-Frequency Interference (RFI) Mitigation: Initial On-Orbit Results (United States)

    Mohammed, Priscilla N.; Piepmeier, Jeffrey R.; Johnson, Joel T.; Aksoy, Mustafa; Bringer, Alexandra


    The Soil Moisture Active Passive (SMAP) mission, launched in January 2015, provides global measurements of soil moisture using a microwave radiometer. SMAPs radiometer passband lies within the passive frequency allocation. However, both unauthorized in-band transmitters as well as out-of-band emissions from transmitters operating at frequencies adjacent to this allocated spectrum have been documented as sources of radio frequency interference (RFI) to the L-band radiometers on SMOS and Aquarius. The spectral environment consists of high RFI levels as well as significant occurrences of low level RFI equivalent to 0.1 to 10 K. The SMAP ground processor reports the antenna temperature both before and after RFI mitigation is applied. The difference between these quantities represents the detected RFI level. The presentation will review the SMAP RFI detection and mitigation procedure and discuss early on-orbit RFI measurements from the SMAP radiometer. Assessments of global RFI properties and source types will be provided, as well as the implications of these results for SMAP soil moisture measurements.

  12. Investigation and Mitigation of the Crosstalk Effect in Terra MODIS Band 30

    Directory of Open Access Journals (Sweden)

    Junqiang Sun


    Full Text Available It has been previously reported that thermal emissive bands (TEB 27–29 in the Terra (T- MODerate resolution Imaging Spectroradiometer (MODIS have been significantly affected by electronic crosstalk. Successful linear theory of the electronic crosstalk effect was formulated, and it successfully characterized the effect via the use of lunar observations as viable inputs. In this paper, we report the successful characterization and mitigation of the electronic crosstalk for T-MODIS band 30 using the same characterization methodology. Though the phenomena of the electronic crosstalk have been well documented in previous works, the novel for band 30 is the need to also apply electronic crosstalk correction to the non-linear term in the calibration coefficient. The lack of this necessity in early works thus demonstrates the distinct difference of band 30, and, yet, in the same instances, the overall correctness of the characterization formulation. For proper result, the crosstalk correction is applied to the band 30 calibration coefficients including the non-linear term, and also to the earth view radiance. We demonstrate that the crosstalk correction achieves a long-term radiometric correction of approximately 1.5 K for desert targets and 1.0 K for ocean scenes. Significant striping removal in the Baja Peninsula earth view imagery is also demonstrated due to the successful amelioration of detector differences caused by the crosstalk effect. Similarly significant improvement in detector difference is shown for the selected ocean and desert targets over the entire mission history. In particular, band 30 detector 8, which has been flagged as “out of family” is restored by the removal of the crosstalk contamination. With the correction achieved, the science applications based on band 30 can be significantly improved. The linear formulation, the characterization methodology, and the crosstalk effect correction coefficients derived using lunar

  13. HST/WFC3: understanding and mitigating radiation damage effects in the CCD detectors (United States)

    Baggett, S. M.; Anderson, J.; Sosey, M.; Gosmeyer, C.; Bourque, M.; Bajaj, V.; Khandrika, H.; Martlin, C.


    At the heart of the Hubble Space Telescope Wide Field Camera 3 (HST/WFC3) UVIS channel is a 4096x4096 pixel e2v CCD array. While these detectors continue to perform extremely well after more than 7 years in low-earth orbit, the cumulative effects of radiation damage are becoming increasingly evident. The result is a continual increase of the hotpixel population and the progressive loss in charge-transfer efficiency (CTE) over time. The decline in CTE has two effects: (1) it reduces the detected source flux as the defects trap charge during readout and (2) it systematically shifts source centroids as the trapped charge is later released. The flux losses can be significant, particularly for faint sources in low background images. In this report, we summarize the radiation damage effects seen in WFC3/UVIS and the evolution of the CTE losses as a function of time, source brightness, and image-background level. In addition, we discuss the available mitigation options, including target placement within the field of view, empirical stellar photometric corrections, post-flash mode and an empirical pixel-based CTE correction. The application of a post-flash has been remarkably effective in WFC3 at reducing CTE losses in low-background images for a relatively small noise penalty. Currently, all WFC3 observers are encouraged to consider post-flash for images with low backgrounds. Finally, a pixel-based CTE correction is available for use after the images have been acquired. Similar to the software in use in the HST Advanced Camera for Surveys (ACS) pipeline, the algorithm employs an observationally-defined model of how much charge is captured and released in order to reconstruct the image. As of Feb 2016, the pixel-based CTE correction is part of the automated WFC3 calibration pipeline. Observers with pre-existing data may request their images from MAST (Mikulski Archive for Space Telescopes) to obtain the improved products.

  14. Crosstalk effect and its mitigation in thermal emissive bands of remote sensors (United States)

    Sun, J.; Madhavan, S.; Wang, M.


    It has been found that there is severe electronic noise in the Terra Moderate Resolution Imaging Spectroradiometer (MODIS) bands 27-30 which corresponds to wavelengths ranging between 6.7 μm to 9.73 μm. The cause for the issue has been identified to be crosstalk, which is significantly amplified since 2010 due to severe degradation in the electronic circuitry. The crosstalk effect causes unexpected discontinuity/change in the calibration coefficients and induces strong striping artifacts in the earth view (EV) images. Also it is noticed, that there are large long-term drifts in the EV brightness temperature (BT) in these bands. An algorithm using a linear approximation derived from on-orbit lunar observations has been developed to correct the crosstalk effect for them. It was demonstrated that the crosstalk correction can remarkably minimize the discontinuity/change in the calibration coefficients, substantially reduce the striping in the EV images, and significantly remove the long-term drift in the EV BT in all these bands. In this paper, we present the recent progresses in the crosstalk effect analysis and its mitigation. In addition, we will show that besides these four bands, the TEBs in other satellite remote sensors also have significant crosstalk contaminations. Further, it will be demonstrated that the crosstalk correction algorithm we developed can be successfully applied to all the contaminated TEBs to significantly reduce the crosstalk effects and substantially improve both the image quality and the radiometric accuracy of Level-1B (L1B) products for the bands.

  15. Simulation of beam-induced plasma for the mitigation of beam-beam effects

    Energy Technology Data Exchange (ETDEWEB)

    Ma, J.; Wang, G.; Samulyak, R.; Yu, K.; Litvinenko, V.


    One of the main challenges in the increase of luminosity of circular colliders is the control of the beam-beam effect. In the process of exploring beam-beam mitigation methods using plasma, we evaluated the possibility of plasma generation via ionization of neutral gas by proton beams, and performed highly resolved simulations of the beam-plasma interaction using SPACE, a 3D electromagnetic particle-in-cell code. The process of plasma generation is modelled using experimentally measured cross-section coefficients and a plasma recombination model that takes into account the presence of neutral gas and beam-induced electromagnetic fields. Numerically simulated plasma oscillations are consistent with theoretical analysis. In the beam-plasma interaction process, high-density neutral gas reduces the mean free path of plasma electrons and their acceleration. A numerical model for the drift speed as a limit of plasma electron velocity was developed. Simulations demonstrate a significant reduction of the beam electric field in the presence of plasma. Preliminary simulations using fully-ionized plasma have also been performed and compared with the case of beam-induced plasma.

  16. The Effects of Climate Sensitivity and Carbon Cycle Interactions on Mitigation Policy Stringency

    Energy Technology Data Exchange (ETDEWEB)

    Calvin, Katherine V.; Bond-Lamberty, Benjamin; Edmonds, James A.; Hejazi, Mohamad I.; Waldhoff, Stephanie T.; Wise, Marshall A.; Zhou, Yuyu


    Climate sensitivity and climate-carbon cycle feedbacks interact to determine how global carbon and energy cycles will change in the future. While the science of these connections is well documented, their economic implications are not well understood. Here we examine the effect of climate change on the carbon cycle, the uncertainty in climate outcomes inherent in any given policy target, and the economic implications. We examine three policy scenarios—a no policy “Reference” (REF) scenario, and two policies that limit total radiative forcing—with four climate sensitivities using a coupled integrated assessment model. Like previous work, we find that, within a given scenario, there is a wide range of temperature change and sea level rise depending on the realized climate sensitivity. We expand on this previous work to show that temperature-related feedbacks on the carbon cycle result in more mitigation required as climate sensitivity increases. Thus, achieving a particular radiative forcing target becomes increasingly expensive as climate sensitivity increases.

  17. Mitigating the Effects of Salinity by Foliar Application of Salicylic Acid in Fenugreek

    Directory of Open Access Journals (Sweden)

    Sumaira Babar


    Full Text Available Present research work was conducted to alleviate the salinity-induced harmful effect on biomass production and physiochemical attributes of fenugreek by foliar application of salicylic acid. Two varieties (Deli Kabul and Kasuri were grown in salt treated (100 mM NaCl and untreated (0 mM NaCl growth medium. Two levels of salicylic acid (0 mg L−1 and 100 mg L−1 were applied through foliar method. Salinity stress significantly reduced the growth biomass in both varieties. Higher shoot fresh weight was recorded in Deli Kabul, while lower in Kasuri. Such reduction in growth biomass was mitigated by the foliar application of SA in both plants. Salinity caused a marked reduction in gas exchange attributes including net CO2 assimilation rate, transpiration rate, stomatal conductance, and substomatal CO2 concentration. Exogenous applied salicylic acid also overcomes the reduction in gas exchange attributes of the plants. The varieties “Deli Kabul” and “Kasuri” showed higher and lower net CO2 assimilation rate, respectively. These results indicate that growth medium salinity induced reduction in biomass production, gas exchange attributes, and also chlorophyll contents whereas the application of SA through foliar method can be used to protect plant growth and improve these attributes under salt stress.

  18. [Preliminary assessment of the potential of biochar technology in mitigating the greenhouse effect in China]. (United States)

    Jiang, Zhi-Xiang; Zheng, Hao; Li, Feng-Min; Wang, Zhen-Yu


    The production of biochar by pyrolysis and its application to soil can sequester the CO2 which was absorbed by plants from atmosphere into soil, in addition it can also bring multiple benefits for agriculture production. On the basis of the available potential survey of the biomass residues from agriculture and forestry section, life cycle assessment was employed to quantify the potential of biochar technology in mitigation of greenhouse gases in our country. The results showed: In China, the amount of available biomass resource was 6.04 x 10(8) t every year and its net greenhouse effect potential was 5.32 x 10(8) t CO(2e) (CO(2e): CO2 equivalent), which was equivalent to 0.88 t CO(2e) for every ton biomass. The greatest of contributor to the total potential was plant carbon sequestration in soil as the form of biochar which accounts for 73.94%, followed by production of renewable energy and its percentage was 23.85%. In summary, production of biochar from agriculture and forestry biomass residues had a significant potential for our country to struggle with the pressure of greenhouse gas emission.

  19. China’s Three Warfares Strategy Mitigates Fallout From Cyber Espionage Activities

    Directory of Open Access Journals (Sweden)

    Emilio Iasiello


    Full Text Available China is engaged in longstanding cyber espionage against the U.S., as well as other nations, to collect sensitive public and private information in support of national objectives laid out in its 12th Five Year Plan. Foreign governments citing China’s malfeasance have rebuked these activities, a claim vehemently denied by Beijing. In response, China is leveraging the “Three Warfares” an integrated three-prong information warfare strategy to combat these accusations by leveraging Media, Legal, and Psychological components designed to influence the international community. While the United States has threatened the imposition of economic sanctions, Beijing has successfully parried consequential actions by arresting U.S.-identified hackers, thereby demonstrating its commitment toward preserving a stable and peaceful cyberspace. These interrelated “Three Warfares” disciplines have targeted the cognitive processes of the U.S. leadership, as well as the international public’s perception of China as a global threat, thereby having successfully forestalled the implementation of any effective punitive or economic deterrence strategy to include the imposition of cyber sanctions.

  20. Combating the effects of climatic change on forests by mitigation strategies

    Directory of Open Access Journals (Sweden)

    Dieter Matthias


    Full Text Available Abstract Background Forests occur across diverse biomes, each of which shows a specific composition of plant communities associated with the particular climate regimes. Predicted future climate change will have impacts on the vulnerability and productivity of forests; in some regions higher temperatures will extend the growing season and thus improve forest productivity, while changed annual precipitation patterns may show disadvantageous effects in areas, where water availability is restricted. While adaptation of forests to predicted future climate scenarios has been intensively studied, less attention was paid to mitigation strategies such as the introduction of tree species well adapted to changing environmental conditions. Results We simulated the development of managed forest ecosystems in Germany for the time period between 2000 and 2100 under different forest management regimes and climate change scenarios. The management regimes reflect different rotation periods, harvesting intensities and species selection for reforestations. The climate change scenarios were taken from the IPCC's Special Report on Emission Scenarios (SRES. We used the scenarios A1B (rapid and successful economic development and B1 (high level of environmental and social consciousness combined with a globally coherent approach to a more sustainable development. Our results indicate that the effects of different climate change scenarios on the future productivity and species composition of German forests are minor compared to the effects of forest management. Conclusions The inherent natural adaptive capacity of forest ecosystems to changing environmental conditions is limited by the long life time of trees. Planting of adapted species and forest management will reduce the impact of predicted future climate change on forests.

  1. Effectiveness of damped braces to mitigate seismic torsional response of unsymmetric-plan buildings (United States)

    Mazza, Fabio; Pedace, Emilia; Favero, Francesco Del


    The seismic retrofitting of unsymmetric-plan reinforced concrete (r.c.) framed buildings can be carried out by the incorporation of damped braces (DBs). Yet most of the proposals to mitigate the seismic response of asymmetric framed buildings by DBs rest on the hypothesis of elastic (linear) structural response. The aim of the present work is to evaluate the effectiveness and reliability of a Displacement-Based Design procedure of hysteretic damped braces (HYDBs) based on the nonlinear behavior of the frame members, which adopts the extended N2 method considered by Eurocode 8 to evaluate the higher mode torsional effects. The Town Hall of Spilinga (Italy), a framed structure with an L-shaped plan built at the beginning of the 1960s, is supposed to be retrofitted with HYDBs to attain performance levels imposed by the Italian seismic code (NTC08) in a high-risk zone. Ten structural solutions are compared by considering two in-plan distributions of the HYDBs, to eliminate (elastic) torsional effects, and different design values of the frame ductility combined with a constant design value of the damper ductility. A computer code for the nonlinear dynamic analysis of r.c. spatial framed structures is adopted to evaluate the critical incident angle of bidirectional earthquakes. Beams and columns are simulated with a lumped plasticity model, including flat surface modeling of the axial load-biaxial bending moment elastic domain at the end sections, while a bilinear law is used to idealize the behavior of the HYDBs. Damage index domains are adopted to estimate the directions of least seismic capacity, considering artificial earthquakes whose response spectra match those adopted by NTC08 at serviceability and ultimate limit states.

  2. State-level infrastructure and economic effects of switchgrass cofiring with coal in existing power plants for carbon mitigation. (United States)

    Morrow, William R; Griffin, W Michael; Matthews, H Scott


    This paper presents a linear programming (LP) methodology for estimating the cost of reducing a state's coal-fired power plant carbon dioxide emissions by cofiring switchgrass and coal. LP modeling allows interplay between regionally specific switchgrass production forecasts, coal plant locations, and individual coal plant historic performance data to determine an allocation of switchgrass minimizing cost or maximizing carbon reduction. The LP methodology is applied to two states, Pennsylvania (PA) and Iowa (IA), and results are presented with a discussion of modeling assumptions, techniques, and carbon mitigation policy implications. The LP methodology estimates that, in PA, 4.9 million tons of CO2/year could be mitigated at an average cost of less than $34/ton of CO2 and that, in IA, 7 million tons of CO2/year could be mitigated at an average Cost of Mitigation of $27/ton of CO2. Because the factors determining the cofiring costs vary so much between the two states, results suggest that cofiring costs will also vary considerably between different U.S. regions. A national level analysis could suggest a lowest-cost cofiring region. This paper presents techniques and assumptions that can simplify biomass energy policy analysis with little effect on analysis conclusions.

  3. Spatial Characteristics of Small Green Spaces' Mitigating Effects on Microscopic Urban Heat Islands (United States)

    Park, J.; Lee, D. K.; Jeong, W.; Kim, J. H.; Huh, K. Y.


    The purpose of the study is to find small greens' disposition, types and sizes to reduce air temperature effectively in urban blocks. The research sites were six high developed blocks in Seoul, Korea. Air temperature was measured with mobile loggers in clear daytime during summer, from August to September, at screen level. Also the measurement repeated over three times a day during three days by walking and circulating around the experimental blocks and the control blocks at the same time. By analyzing spatial characteristics, the averaged air temperatures were classified with three spaces, sunny spaces, building-shaded spaces and small green spaces by using Kruskal-Wallis Test; and small green spaces in 6 blocks were classified into their outward forms, polygonal or linear and single or mixed. The polygonal and mixed types of small green spaces mitigated averaged air temperature of each block which they belonged with a simple linear regression model with adjusted R2 = 0.90**. As the area and volume of these types increased, the effect of air temperature reduction (ΔT; Air temperature difference between sunny space and green space in a block) also increased in a linear relationship. The experimental range of this research is 100m2 ~ 2,000m2 of area, and 1,000m3 ~ 10,000m3 of volume of small green space. As a result, more than 300m2 and 2,300m3 of polygonal green spaces with mixed vegetation is required to lower 1°C; 650m2 and 5,000m3 of them to lower 2°C; about 2,000m2 and about 10,000m3 of them to lower 4°C air temperature reduction in an urban block.

  4. Mitigating Adverse Effects of a Human Mission on Possible Martian Indigenous Ecosystems (United States)

    Lupisella, M. L.


    Although human beings are, by most standards, the most capable agents to search for and detect extraterrestrial life, we are also potentially the most harmful. While there has been substantial work regarding forward contamination with respect to robotic missions, the issue of potential adverse effects on possible indigenous Martian ecosystems, such as biological contamination, due to a human mission has remained relatively unexplored and may require our attention now as this presentation will try to demonstrate by exploring some of the relevant scientific questions, mission planning challenges, and policy issues. An informal, high-level mission planning decision tree will be discussed and is included as the next page of this abstract. Some of the questions to be considered are: (1) To what extent could contamination due to a human presence compromise possible indigenous life forms? (2) To what extent can we control contamination? For example, will it be local or global? (3) What are the criteria for assessing the biological status of Mars, both regionally and globally? For example, can we adequately extrapolate from a few strategic missions such as sample return missions? (4) What should our policies be regarding our mission planning and possible interaction with what are likely to be microbial forms of extraterrestrial life? (5) Central to the science and mission planning issues is the role and applicability of terrestrial analogs, such as Lake Vostok for assessing drilling issues, and modeling techniques. Central to many of the policy aspects are scientific value, international law, public concern, and ethics. Exploring this overall issue responsibly requires an examination of all these aspects and how they interrelate. A chart is included, titled 'Mission Planning Decision Tree for Mitigating Adverse Effects to Possible Indigenous Martian Ecosystems due to a Human Mission'. It outlines what questions scientists should ask and answer before sending humans to Mars.

  5. Soil management system for water conservation and mitigation of global change effect (United States)

    Ospina, A.; Florentino, A.; Lorenzo, V.


    One of the main constraints in rained agriculture is the water availability for plant growth which depends largely on the ability of the soil to allow water flow, infiltration and its storage. In Venezuela, the interaction between aggressive climatic conditions, highly susceptible soils and inadequate management systems have caused soil degradation which together with global change threatened the food production sustainability. To address this problem, we need to implement conservationist management strategies that improve infiltration rate, permeability and water holding capacity in soil and reduce water loss by protecting the soil surface. In order to study the impact of different management systems on soil water balance in a Fluventic Haplustept, the effects of 11 years of tillage and crops rotation management were evaluated in a long term field experiment located in Turén (Portuguesa state). The evaluated tillage systems were no tillage (NT) and conventional tillage (CT) and crop rotation treatments were maize (Zea mays)-cotton (Gossypium hirsutum) and maize-bean (Vigna unguiculata). Treatments were established in plots arranged in a randomized block design with three replicates. The gravimetric moisture content was determined in the upper 20 cm of soil, at eight different sampling dates. Results showed increased in time of the water availability with the use of tillage and corn-cotton rotation and, better protection of the soil against raindrop impact with crop residues. Water retention capacity also increased and improved structural condition on soil surface such as infiltration, storage and water flow distribution in the rooting zone. We conclude that these strategies of land use and management would contribute to mitigate the climate change effects on food production in this region of Venezuela. Key words: Soil quality; rained agriculture; plant water availability

  6. Mitigation of ground motion effects via feedback systems in the Compact Linear Collider

    CERN Document Server

    Pfingstner, Jürgen; Schmickler, Hermann; Schulte, Daniel

    The Compact Linear Collider (CLIC) is a future multi-TeV electron positron collider, which is currently being designed at CERN. To achieve its ambitious goals, CLIC has to produce particle beams of the highest quality, which makes the accelerator very sensitive to ground motion. Four mitigation methods have been foreseen by the CLIC design group to cope with the feasibility issue of ground motion. This thesis is concerned with the design of one of these mitigation methods, named linac feedback (L-FB), but also with the simultaneous simulation and validation of all mitigation methods. Additionally, a technique to improve the quality of the indispensable system knowledge has been developed. The L-FB suppresses beam oscillations along the accelerator. Its design is based on the decoupling of the overall accelerator system into independent channels. For each channel an individual compensator is found with the help of a semi- automatic control synthesis procedure. This technique allows the designer to incorporate ...

  7. Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia. (United States)

    Yang, Dianer; Sun, Yu-Yo; Nemkul, Niza; Baumann, Jessica M; Shereen, Ahmed; Dunn, R Scott; Wills-Karp, Marsha; Lawrence, Daniel A; Lindquist, Diana M; Kuan, Chia-Yi


    Intrauterine infection exacerbates neonatal hypoxic-ischemic (HI) brain injury and impairs the development of cerebral cortex. Here we used low-dose lipopolysaccharide (LPS) pre-exposure followed by unilateral cerebral HI insult in 7-day-old rats to study the pathogenic mechanisms. We found that LPS pre-exposure blocked the HI-induced proteolytic activity of tissue-type plasminogen activator (tPA), but significantly enhanced NF-κB signaling, microglia activation, and the production of pro-inflammatory cytokines in newborn brains. Remarkably, these pathogenic responses were all blocked by intracerebroventricular injection of a stable-mutant form of plasminogen activator protein-1 called CPAI. Similarly, LPS pre-exposure amplified, while CPAI therapy mitigated HI-induced blood-brain-barrier damage and the brain tissue loss with a therapeutic window at 4 h after the LPS/HI insult. The CPAI also blocks microglia activation following a brain injection of LPS, which requires the contribution by tPA, but not the urinary-type plasminogen activator (uPA), as shown by experiments in tPA-null and uPA-null mice. These results implicate the nonproteolytic tPA activity in LPS/HI-induced brain damage and microglia activation. Finally, the CPAI treatment protects near-normal motor and white matter development despite neonatal LPS/HI insult. Together, because CPAI blocks both proteolytic and nonproteolytic tPA neurotoxicity, it is a promising therapeutics of neonatal HI injury either with or without infection.

  8. [Effects of elemental sulphur and dicyandiamide on mitigating NO3- -N leaching loss from vegetable soil]. (United States)

    Zhao, Yanwen; Liu, Changzhen; Hu, Zhengyi; Gao, Yimin; Wang, Cairong; Bi, Dongmei


    In a pot experiment with allium as test plant and NH4HCO3 as nitrogen source, this paper studied the effects of element sulphur (S0) and dicyandiamide (DCD) on mitigating the NO3- -N leaching loss from soil and on soil inorganic nitrogen (NO3- -N and NH4+ -N) content. The results showed that within the 12 weeks of the experiment, the cumulative leaching loss of soil NO3- -N in treatments S0 + DCD and S0 was 83%-86% and 83% lower, while that of soil NH4+ -N was 16.8-21.0 mg x pot(-1) and 20.4-25.0 mg x pot(-1) higher than CK, respectively, and the cumulative loss of soil (NH4+ + NO3-)-N was 60% lower. By the end of the experiment, soil inorganic nitrogen content in treatments S0 + DCD and S0 was 79.9%-85.4% and 74.9-82.6% higher than CK, respectively. The cumulative leaching loss of inorganic N in treatment S0 + DCD was 4.6%-14.4% and 15.4%-30.1% lower, and the soil inorganic nitrogen content by the end of the experiment was 6.1% and 16.8%-36.0% higher than that of treatments S0 and DCD, respectively. Similar results were obtained when S0 was replaced by Na2S2O3, but not by Na2SO4. The fact that the application of S0 could obviously decrease the NO3- -N leaching loss from soil could be contributed to the inhibitory effects of S2O3(2-) and S4O6(2-) originated from S0 oxidation in soil on the nitrification of NH4+ -N. S0 could retard the decomposition of DCD due to the effect of its oxidized products S2O3(2-) and S4O6(2-), and thus, extend the inhibitory effect of DCD on NH4+ -N nitrification. It is suggested that S0 combined with DCD could be used as an effective nitrification inhibitor to control the NO3- -N leaching loss from vegetable soils.

  9. Under-Body Blast Mitigation: Stand-Alone Seat Safety Activation System (United States)


    INTRODUCTION The challenge of protecting occupants during an underbody blast is being able to sense and activate systems (such as pyrotechnic...As such Constant-Flux Magnetostrictive Sensors shall be evaluated in a self-contained environment to provide the output during these events. By...Constant-Flux Magnetostrictive Sensors shall be evaluated in a self-contained environment to provide the output during these events. By activating the

  10. Method for mitigating the negative effect of vortex motion inside the suction chambers of centrifugal pumps

    Directory of Open Access Journals (Sweden)

    Adrian CIOCANEA


    Full Text Available The paper presents a method for mitigating the negative effect of vortex motion inside the suction chambers of centrifugal pumps in order to obtain better use of water resource and decrease the risk related to loss of prime. It was studied the influence of a rotating device on the vortex motion in the case of a vertical suction pipe. The device is consisting of three thin vertical cylinders symmetrically mounted on a horizontal rotating disk placed in front of the inlet section of the suction pipe. The experimental research was conducted for various diameters of the cylinders, water levels in the suction chamber and pump flow rates. It was assessed the vortex type, frequency of arising and living life of vortices. The experimental results are compared with the case the device is absent in order to assess the efficiency of the solution. By using the device a decrease of about 1215% of vortex arising is observed for most of the water levels in the suction chamber and for 80 -90 % of the centrifugal pump flow rates. If high flow rates and low water level in the suction chamber are simultaneously present, violent vortex motion is blocking the rotating device and the volume of air entered the pipe is massive - extreme regime. The flow pattern in the suction chamber was visualized using a laser sheet. At the inlet section of the suction pipe one can observe two main flow patterns: central vortex entrance for high water level in the suction chamber and reduce flow rates of the centrifugal pump and lateral vortex entrance for low water level and high flow rates. The conclusions of the experiment confirm the energy dissipation of the vortices arising in the suction chamber, due to utilization of the rotating device, in most of the centrifugal pump regimes.

  11. Atmospheric particulate mercury in the megacity Beijing: Efficiency of mitigation measures and assessment of health effects (United States)

    Schleicher, N. J.; Schäfer, J.; Chen, Y.; Blanc, G.; Chen, Y.; Chai, F.; Cen, K.; Norra, S.


    Atmospheric particulate mercury (HgP) was studied before, during, and after the Olympic Summer Games in Beijing, China, in August 2008 in order to investigate the efficiency of the emission control measures implemented by the Chinese Government. These source control measures comprised traffic reductions, increase in public transportation, planting of vegetation, establishment of parks, building freeze at construction sites, cleaner production techniques for industries and industry closures in Beijing and also in the surrounding areas. Strictest measures including the "odd-even ban" to halve the vehicle volume were enforced from the 20th of July to the 20th of September 2008. The Olympic period provided the unique opportunity to investigate the efficiency of these comprehensive actions implemented in order to reduce air pollution on a large scale. Therefore, the sampling period covered summer (August, September) and winter (December and January) samples over several years from December 2005 to September 2013. Average HgP concentrations in total suspended particulates (TSP) sampled in August 2008 were 81 ± 39 pg/m3 while TSP mass concentrations were 93 ± 49 μg/m3. This equals a reduction by about 63% for TSP mass and 65% for HgP, respectively, compared to the previous two years demonstrating the short-term success of the measures. However, after the Olympic Games, HgP concentrations increased again to pre-Olympic levels in August 2009 while values in August 2010 decreased again by 30%. Moreover, winter samples, which were 2- to 11-fold higher than corresponding August values, showed decreasing concentrations over the years indicating a long-term improvement of HgP pollution in Beijing. However, regarding adverse health effects, comparisons with soil guideline values and studies from other cities highlighted that HgP concentrations in TSP remained high in Beijing despite respective control measures. Consequently, future mitigation measures need to be tailored more

  12. A wedge-based approach to estimating health co-benefits of climate change mitigation activities in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Balbus, John M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Greenblatt, Jeffery B. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Chari, Ramya [Rand Corporation, Santa Monica, CA (United States); Millstein, Dev [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Ebi, Kristie L. [ClimAdapt, Inc., Los Altos, CA (United States)


    While it has been recognized that actions reducing greenhouse gas (GHG) emissions can have significant positive and negative impacts on human health through reductions in ambient fine particulate matter (PM2.5) concentrations, these impacts are rarely taken into account when analyzing specific policies. This study presents a new framework for estimating the change in health outcomes resulting from implementation of specific carbon dioxide (CO2) reduction activities, allowing comparison of different sectors and options for climate mitigation activities. Our estimates suggest that in the year 2020, the reductions in adverse health outcomes from lessened exposure to PM2.5 would yield economic benefits in the range of $6 to $14 billion (in 2008 USD), depending on the specific activity. This equates to between $40 and $93 per metric ton of CO2 in health benefits. Specific climate interventions will vary in the health co-benefits they provide as well as in potential harms that may result from their implementation. Rigorous assessment of these health impacts is essential for guiding policy decisions as efforts to reduce GHG emissions increase in scope and intensity.

  13. Mitigation of greenhouse gas emissions from reed canary grass in paludiculture: effect of groundwater level

    DEFF Research Database (Denmark)

    Karki, Sandhya; Elsgaard, Lars; Audet, Joachim


    Background and aims Combination of rewetting and wetland crop cultivation (paludiculture) is pursued as a wider carbon dioxide (CO2) mitigation option in drained peatland. However, information on the overall greenhouse gas (GHG) balance for paludiculture is lacking. We investigated the GHG balance...

  14. How effective is road mitigation at reducing road-kill? A meta-analysis

    NARCIS (Netherlands)

    Rytwinski, Trina; Soanes, Kylie; Jaeger, Jochen A.G.; Fahrig, Lenore; Findlay, C.S.; Houlahan, Jeff; Ree, van der Rodney; Grift, van der Edgar A.


    Road traffic kills hundreds of millions of animals every year, posing a critical threat to the
    populations of many species. To address this problem there are more than forty types of
    road mitigation measures available that aim to reduce wildlife mortality on roads (road-kill).
    For road p

  15. Modelling the cost-effectiveness of mitigation methods for multiple pollutants at farm scale. (United States)

    Gooday, R D; Anthony, S G; Chadwick, D R; Newell-Price, P; Harris, D; Duethmann, D; Fish, R; Collins, A L; Winter, M


    Reductions in agricultural pollution are essential for meeting nationally and internationally agreed policy targets for losses to both air and water. Numerous studies quantify the impact of relevant mitigation methods by field experimentation or computer modelling. The majority of these studies have addressed individual methods and frequently also individual pollutants. This paper presents a conceptual model for the synthesis of the evidence base to calculate the impact of multiple methods addressing multiple pollutants in order to identify least cost solutions for multiple policy objectives. The model is implemented as a farm scale decision support tool that quantifies baseline pollutant losses for identifiable sources, areas and pathways and incorporates a genetic algorithm based multi-objective procedure for determining optimal suites of mitigation methods. The tool is generic as baseline losses can be replaced with measured data and the default library of mitigation methods can be edited and expanded. The tool is demonstrated through application to two contrasting farm systems, using survey data on agricultural practices typical of England and Wales. These examples show how the tool could be used to help target the adoption of mitigation options for the control of diffuse pollution from agriculture. The feedback from workshops where Farmscoper was demonstrated is included to highlight the potential role of Farmscoper as part of the farm advisory process.

  16. Mitigating effects of the home environment on inattention and overactivity in children adopted from Romanian orphanages: a longitudinal study


    Audet, Karyn Nicole


    This longitudinal study examined the potential mitigating effects of the adoptive home environment on inattention and overactivity (I/O) in children adopted from Romanian orphanages. Three groups were studied: (1) Children who experienced at least 8 months of deprivation in an orphanage prior to being adopted to British Columbia (RO group), (2) Children adopted to British Columbia from Romanian orphanages prior to 4-months-of-age (EA group), and (3) Canadian born non-adopted children (CB grou...

  17. Forestry for mitigating the greenhouse effect : an ecological and economic assessment of the potential of land use to mitigate CO2 emissions in the Highlands of Chiapas, Mexico

    NARCIS (Netherlands)

    Jong, de B.H.J.


    The present study intends to answer some of the important questions that arise when translating projects that have an ecological potential to mitigate carbon excesses, into actual implementation of these projects in a farmer-dominated landscape. Farm and community forestry projects for greenhouse ga

  18. Spatial and temporal spread of flood mitigation measures implemented by private households along the Rhine and their effectiveness (United States)

    Bubeck, P.; Kreibich, H.; Botzen, W. J. W.; Aerts, J. C. J. H.


    Floods in Europe caused substantial economic damage in recent decades. In the future, flood risk is projected to increase in many places due to the effects of climate change and on-going socio-economic development in flood-prone areas. To reduce the economic impact of current and future floods, damage mitigation measures implemented by private households are increasingly considered as an important component of integrated flood risk management approaches. However, knowledge about the temporal and spatial spread of flood mitigation measures such as water barriers or adapted building use are often lacking. Moreover, estimates of the effectiveness of these measures are still scarce. To gain further insights into these aspects, we will present empirical data from a computer-aided telephone survey among 752 private households along the German part of the River Rhine. It will be discussed to what extent various types of flood mitigation measures have been implemented by private households in flood-prone areas over time. Currently, we find that several measures, e.g. flood-adapted building use are regularly employed by the population at risk (34 per cent). We will examine to what extent the deployment of these measures effectively contributes to damage reduction.

  19. Impact hazard mitigation: understanding the effects of nuclear explosive outputs on comets and asteroids

    Energy Technology Data Exchange (ETDEWEB)

    Clement, Ralph R C [Los Alamos National Laboratory; Plesko, Catherine S [Los Alamos National Laboratory; Bradley, Paul A [Los Alamos National Laboratory; Conlon, Leann M [Los Alamos National Laboratory


    The NASA 2007 white paper ''Near-Earth Object Survey and Deflection Analysis of Alternatives'' affirms deflection as the safest and most effective means of potentially hazardous object (PHO) impact prevention. It also calls for further studies of object deflection. In principle, deflection of a PHO may be accomplished by using kinetic impactors, chemical explosives, gravity tractors, solar sails, or nuclear munitions. Of the sudden impulse options, nuclear munitions are by far the most efficient in terms of yield-per-unit-mass launched and are technically mature. However, there are still significant questions about the response of a comet or asteroid to a nuclear burst. Recent and ongoing observational and experimental work is revolutionizing our understanding of the physical and chemical properties of these bodies (e.g ., Ryan (2000) Fujiwara et al. (2006), and Jedicke et al. (2006)). The combination of this improved understanding of small solar-system bodies combined with current state-of-the-art modeling and simulation capabilities, which have also improved dramatically in recent years, allow for a science-based, comprehensive study of PHO mitigation techniques. Here we present an examination of the effects of radiation from a nuclear explosion on potentially hazardous asteroids and comets through Monte Carlo N-Particle code (MCNP) simulation techniques. MCNP is a general-purpose particle transport code commonly used to model neutron, photon, and electron transport for medical physics reactor design and safety, accelerator target and detector design, and a variety of other applications including modeling the propagation of epithermal neutrons through the Martian regolith (Prettyman 2002). It is a massively parallel code that can conduct simulations in 1-3 dimensions, complicated geometries, and with extremely powerful variance reduction techniques. It uses current nuclear cross section data, where available, and fills in the gaps with

  20. Effects and Mitigation of Clear Sky Sampling on Recorded Trends in Land Surface Temperature (United States)

    Holmes, T. R.; Hain, C.; de Jeu, R.; Anderson, M. C.; Crow, W. T.


    Land surface temperature (LST) is a key input for physically-based retrieval algorithms of hydrological states and fluxes. Yet, it remains a poorly constrained parameter for global scale studies. The main two observational methods to remotely measure T are based on thermal infrared (TIR) observations and passive microwave observations (MW). TIR is the most commonly used approach and the method of choice to provide standard LST products for various satellite missions. MW-based LST retrievals on the other hand are not as widely adopted for land applications; currently their principle use is in soil moisture retrieval algorithms. MW and TIR technologies present two highly complementary and independent means of measuring LST. MW observations have a high tolerance to clouds but a low spatial resolution, and TIR has a high spatial resolution with temporal sampling restricted to clear skies. This paper builds on recent progress in characterizing the main structural differences between TIR LST and MW Ka-band observations, the MW frequency that is most suitable for LST sensing. By accounting for differences in diurnal timing (phase lag with solar noon), amplitude, and emissivity we construct a MW-based LST dataset that matches the diurnal characteristics of the TIR-based LSA SAF LST record. This new global dataset of MW-based LST currently spans the period of 2003-2013. In this paper we will present results of a validation of MW LST with in situ data with special emphasis on the effect of cloudiness on the performance. The ability to remotely sense the temperature of cloud covered land is what sets this MW-LST datasets apart from existing (much higher resolution) TIR-based products. As an example of this we will therefore explore how MW LST can mitigate the effect of clear-sky sampling in the context of trend and anomaly detection. We do this by contrasting monthly means of TIR-LST with its clear-sky and all-sky equivalent from an MW-LST and an NWP model.

  1. Soot effects on clouds and solar absorption: Understanding the differences in recently published soot mitigation experiments. (Invited) (United States)

    Bauer, S. E.; Menon, S.


    Attention has been drawn to black carbon aerosols, as a target for short-term mitigation of climate warming. This measure seems attractive because soot is assumed to warm the atmosphere and at the same time has a lifetime of just a few days. Therefore regulating soot emissions could, as a short-term action, potentially buy time by slowing global warming until regulations for longer lived greenhouse gases are set in place. Currently the scientific community debates the impacts of such mitigation measures, especially when considering indirect effects. We tested with the GISS/MATRIX model, a global climate model including detailed aerosol microphysics, the effect of reducing fossil fuel emissions and bio-fuel emissions and found that opposite changes in cloud droplet number concentration lead to positive cloud forcing numbers in the bio-fuel reduction case and negative forcing numbers in the diesel mitigation case. Similar experiments have been carried out and have recently been published by other modeling groups, finding partly similar partly contradicting results to our study. In this presentation we want to explain the differences in black carbon research carried out with complex microphysical models, by focusing on the treatment of mixing state, and separation between forcings and feedbacks.

  2. A Shock Mitigation of Pedestrian-Vehicle Impact Using Active Hood Lift System: Deploying Time Investigation

    Directory of Open Access Journals (Sweden)

    Tae-Hoon Lee


    Full Text Available This paper investigates the deploying time (or response time of an active hood lift system (AHLS of a passenger vehicle activated by gunpowder actuator. In this work, this is accomplished by changing principal design parameters of the latch part mechanism of the hood system. After briefly introducing the working principle of the AHLS operated by the gunpowder actuator, the governing equations of the AHLS are formulated for each different deploying motion. Subsequently, using the governing equations, the response time for deploying the hold lift system is determined by changing several geometric distances such as the distance from the rotational center of the pop-up guide to the point of the latch in the axial and vertical directions. Then, a comparison is made of the total response time to completely deploy the hood lift system with the existing conventional AHLS and proposed AHLS. In addition, the workable driving speed of the proposed AHLS is compared with the conventional one by changing the powder volume of the actuator.

  3. Effects of Building a Sand Barrier Berm to Mitigate the Effects of the Deepwater Horizon Oil Spill on Louisiana Marshes (United States)

    Lavoie, Dawn; Flocks, James G.; Kindinger, Jack G.; Sallenger, A.H.; Twichell, David C.


    The State of Louisiana requested emergency authorization on May 11, 2010, to perform spill mitigation work on the Chandeleur Islands and on all the barrier islands from Grand Terre Island eastward to Sandy Point to enhance the capability of the islands to reduce the movement of oil from the Deepwater Horizon oil spill to the marshes. The proposed action-building a barrier berm (essentially an artificial island fronting the existing barriers and inlets) seaward of the existing barrier islands and inlets-'restores' the protective function of the islands but does not alter the islands themselves. Building a barrier berm to protect the mainland wetlands from oil is a new strategy and depends on the timeliness of construction to be successful. Prioritizing areas to be bermed, focusing on those areas that are most vulnerable and where construction can be completed most rapidly, may increase chances for success. For example, it may be easier and more efficient to berm the narrow inlets of the coastal section to the west of the Mississippi River Delta rather than the large expanses of open water to the east of the delta in the southern parts of the Breton National Wildlife Refuge (NWR). This document provides information about the potential available sand resources and effects of berm construction on the existing barrier islands. The proposed project originally involved removing sediment from a linear source approximately 1 mile (1.6 km) gulfward of the barrier islands and placing it just seaward of the islands in shallow water (~2-m depth where possible) to form a continuous berm rising approximately 6 feet (~2 m) above sea level (North American Vertical Datum of 1988-NAVD88) with an ~110-yd (~100-m) width at water level and a slope of 25:1 to the seafloor. Discussions within the U.S. Geological Survey (USGS) and with others led to the determination that point-source locations, such as Hewes Point, the St. Bernard Shoals, and Ship Shoal, were more suitable 'borrow

  4. Activation of WIP1 phosphatase by HTLV-1 Tax mitigates the cellular response to DNA damage.

    Directory of Open Access Journals (Sweden)

    Tajhal Dayaram

    Full Text Available Genomic instability stemming from dysregulation of cell cycle checkpoints and DNA damage response (DDR is a common feature of many cancers. The cancer adult T cell leukemia (ATL can occur in individuals infected with human T cell leukemia virus type 1 (HTLV-1, and ATL cells contain extensive chromosomal abnormalities, suggesting that they have defects in the recognition or repair of DNA damage. Since Tax is the transforming protein encoded by HTLV-1, we asked whether Tax can affect cell cycle checkpoints and the DDR. Using a combination of flow cytometry and DNA repair assays we showed that Tax-expressing cells exit G(1 phase and initiate DNA replication prematurely following damage. Reduced phosphorylation of H2AX (γH2AX and RPA2, phosphoproteins that are essential to properly initiate the DDR, was also observed in Tax-expressing cells. To determine the cause of decreased DDR protein phosphorylation in Tax-expressing cells, we examined the cellular phosphatase, WIP1, which is known to dephosphorylate γH2AX. We found that Tax can interact with Wip1 in vivo and in vitro, and that Tax-expressing cells display elevated levels of Wip1 mRNA. In vitro phosphatase assays showed that Tax can enhance Wip1 activity on a γH2AX peptide target by 2-fold. Thus, loss of γH2AX in vivo could be due, in part, to increased expression and activity of WIP1 in the presence of Tax. siRNA knockdown of WIP1 in Tax-expressing cells rescued γH2AX in response to damage, confirming the role of WIP1 in the DDR. These studies demonstrate that Tax can disengage the G(1/S checkpoint by enhancing WIP1 activity, resulting in reduced DDR. Premature G(1 exit of Tax-expressing cells in the presence of DNA lesions creates an environment that tolerates incorporation of random mutations into the host genome.

  5. Aperture Effects on Spectroscopic Galaxy Activity Classification

    CERN Document Server

    Maragkoudakis, A; Ashby, M L N; Willner, S P


    Activity classification of galaxies based on long-slit and fiber spectroscopy can be strongly influenced by aperture effects. Here we investigate how activity classification for 14 nearby galaxies depends on the proportion of the host galaxy's light that is included in the aperture. We use both observed long-slit spectra and simulated elliptical-aperture spectra of different sizes. The degree of change varies with galaxy morphology and nuclear activity type. Starlight removal techniques can mitigate but not remove the effect of host galaxy contamination in the nuclear aperture. Galaxies with extra-nuclear star formation can show higher [O III] {\\lambda}5007/H{\\beta} ratios with increasing aperture, in contrast to the naive expectation that integrated light will only dilute the nuclear emission lines. We calculate the mean dispersion for the diagnostic line ratios used in the standard BPT diagrams with respect to the central aperture of spectral extraction to obtain an estimate of the uncertainties resulting f...

  6. Residual flood-risk: assessing the effectiveness of alternative large-scale mitigation strategies (United States)

    Carisi, Francesca; Domeneghetti, Alessio; Castellarin, Attilio


    The EU Flood Directive (2007/60/CE) requires institutions and public bodies, in order to formulate robust flood-risk management strategies for large European rivers, to address several fundamental tasks. For instance, they have to address the problem of flood-risk mitigation from a global perspective (i.e., entire middle-lower river reaches) by identifying critical reaches, inundation areas and corresponding overflow volumes. To this aim, we focus on the identification of large-scale flood risk mitigation strategies for the middle-lower reach of the Po river, the longest Italian river and the largest in terms of streamflow. We refer to the so-called residual flood-risk and in particular to its portion referring to the possibility to experience events associated with larger return periods than the reference one (e.g. ~200 years in our case). In particular, being a further levee heightening not technically viable nor economically conceivable for the case study, the study develops and tests the applicability of a quasi-2D hydraulic model for the identification of large-scale flood-risk mitigation strategies relative to a 500-year flood event. In particular, we consider and model in the study different geometrical configurations of the main embankment system for a ~400km reach stretching from Isola S.Antonio to the Po river delta in the Adriatic Sea: overtopping without levee breaching, overtopping and natural levee breaching, overtopping and forced levee breaching. The simulations enable the assessment of the overflowed volumes and water depths on flooded areas. Expected damages are estimated using simplified graphical tools, which we termed "Vulnerability Hypsometric Curves" (HVCs) and report the extent of the area for a given land use category that is located below a certain elevation. The analysis aims at finding the optimal configuration that minimizes the expected damages in the areas prone to flood. The outcomes of our study indicate that coupling a large

  7. The sperm whale sonar: Monitoring and use in mitigation of anthropogenic noise effects in the marine environment

    Energy Technology Data Exchange (ETDEWEB)

    Andre, Michel [Laboratory of Applied Bioacoustics, Technical University of Catalonia, Barcelona 08800 (Spain)], E-mail:


    Noise pollution in the marine environment is an emerging but serious concern. Its implications are less well understood than other global threats and largely undetectable to everyone but the specialist. In addition, the assessment of the acoustic impact of artificial sounds in the sea is not a trivial task, certainly because there is a lack of information on how the marine organisms process and analyse sounds and how relevant these sounds are for the balance and development of the populations. Further, this possible acoustic impact not only concerns the hearing systems but may also affect other sensory or systemic levels and result equally lethal for the animal concerned. If we add that the negative consequences of a short or long term exposure to artificial sounds may not be immediately observed one can understood how challenging it is to obtain objective data allowing an efficient control of the introduction of anthropogenic sound in the sea. To answer some of these questions, the choice to investigate cetaceans and their adaptation to an aquatic environment is not fortuitous. Cetaceans, because of their optimum use of sound as an ad-hoc source of energy and their almost exclusive dependence on acoustic information, represent not only the best bio-indicator of the effects of noise pollution in the marine environment, but also a source of data to improve and develop human underwater acoustic technology. Here, we present how the characteristics and performance of the sperm whale mid-range biosonar can be used to develop a mitigation solution based on passive acoustics and ambient noise imaging to prevent negative interactions with human activities by monitoring cetacean movements in areas of interest, e.g. deep-sea observatories.

  8. The sperm whale sonar: Monitoring and use in mitigation of anthropogenic noise effects in the marine environment (United States)

    André, Michel


    Noise pollution in the marine environment is an emerging but serious concern. Its implications are less well understood than other global threats and largely undetectable to everyone but the specialist. In addition, the assessment of the acoustic impact of artificial sounds in the sea is not a trivial task, certainly because there is a lack of information on how the marine organisms process and analyse sounds and how relevant these sounds are for the balance and development of the populations. Further, this possible acoustic impact not only concerns the hearing systems but may also affect other sensory or systemic levels and result equally lethal for the animal concerned. If we add that the negative consequences of a short or long term exposure to artificial sounds may not be immediately observed one can understood how challenging it is to obtain objective data allowing an efficient control of the introduction of anthropogenic sound in the sea. To answer some of these questions, the choice to investigate cetaceans and their adaptation to an aquatic environment is not fortuitous. Cetaceans, because of their optimum use of sound as an ad-hoc source of energy and their almost exclusive dependence on acoustic information, represent not only the best bio-indicator of the effects of noise pollution in the marine environment, but also a source of data to improve and develop human underwater acoustic technology. Here, we present how the characteristics and performance of the sperm whale mid-range biosonar can be used to develop a mitigation solution based on passive acoustics and ambient noise imaging to prevent negative interactions with human activities by monitoring cetacean movements in areas of interest, e.g. deep-sea observatories.

  9. Flight Services and Aircraft Access: Active Flow Control Vertical Tail and Insect Accretion and Mitigation Flight Test (United States)

    Whalen, Edward A.


    This document serves as the final report for the Flight Services and Aircraft Access task order NNL14AA57T as part of NASA Environmentally Responsible Aviation (ERA) Project ITD12A+. It includes descriptions of flight test preparations and execution for the Active Flow Control (AFC) Vertical Tail and Insect Accretion and Mitigation (IAM) experiments conducted on the 757 ecoDemonstrator. For the AFC Vertical Tail, this is the culmination of efforts under two task orders. The task order was managed by Boeing Research & Technology and executed by an enterprise-wide Boeing team that included Boeing Research & Technology, Boeing Commercial Airplanes, Boeing Defense and Space and Boeing Test and Evaluation. Boeing BR&T in St. Louis was responsible for overall Boeing project management and coordination with NASA. The 757 flight test asset was provided and managed by the BCA ecoDemonstrator Program, in partnership with Stifel Aircraft Leasing and the TUI Group. With this report, all of the required deliverables related to management of this task order have been met and delivered to NASA as summarized in Table 1. In addition, this task order is part of a broader collaboration between NASA and Boeing.

  10. Can migration mitigate the effects of ecosystem change? Patterns of dispersal, energy acquisition and allocation in Great Lakes lake whitefish (Coregonus clupeaformis) (United States)

    Rennie, Michael D.; Ebener, Mark P.; Wagner, Tyler


    Migration can be a behavioural response to poor or declining home range habitat quality and can occur when the costs of migration are overcome by the benefi ts of encountering higher-quality resources elsewhere. Despite dramatic ecosystem-level changes in the benthic food web of the Laurentian Great Lakes since the colonization of dreissenid mussels, coincident changes in condition and growth rates among benthivorous lake whitefi sh populations have been variable. We hypothesized that this variation could be in part mitigated by differences in migratory habits among populations, where increased migration distance can result in an increased probability of encountering high-quality habitat (relative to the home range). Results from four Great Lakes populations support this hypothesis; relative growth rates increased regularly with migration distance. The population with the largest average migration distance also had the least reduction in size-at-age during a period of signifi cant ecosystem change and among the highest estimated consumption and activity rates. In comparison, the population with the greatest declines in size-at-age was among the least mobile, demonstrating only moderate rates of consumption and activity. The least mobile population of lake whitefi sh was supported by a remnant Diporeia population and has experienced only moderate temporal growth declines. Our study provides evidence for the potential role of migration in mitigating the effects of ecosystem change on lake whitefi sh populations.

  11. Acrylamide mitigation strategies

    NARCIS (Netherlands)

    Palermo, M.; Gökmen, V.; Meulenaer, De B.; Ciesarová, Z.; Zhang, Y.; Pedreschi, F.; Fogliano, V.


    FoodDrinkEurope Federation recently released the latest version of the Acrylamide Toolbox to support manufacturers in acrylamide reduction activities giving indication about the possible mitigation strategies. The Toolbox is intended for small and medium size enterprises with limited R&D reso

  12. Investigating the effect of two methane-mitigating diets on the rumen microbiome using massively parallel sequencing. (United States)

    Ross, E M; Moate, P J; Marett, L; Cocks, B G; Hayes, B J


    Variation in the composition of microorganisms in the rumen (the rumen microbiome) of dairy cattle (Bos taurus) is of great interest because of possible links to methane emission levels. Feed additives are one method being investigated to reduce enteric methane production by dairy cattle. Here we report the effect of 2 methane-mitigating feed additives (grapemarc and a combination of lipids and tannin) on rumen microbiome profiles of Holstein dairy cattle. We used untargeted (shotgun) massively parallel sequencing of microbes present in rumen fluid to generate quantitative rumen microbiome profiles. We observed large effects of the feed additives on the rumen microbiome profiles using multiple approaches, including linear mixed modeling, hierarchical clustering, and metagenomic predictions. The effect on the fecal microbiome profiles was not detectable using hierarchical clustering, but was significant in the linear mixed model and when metagenomic predictions were used, suggesting a more subtle effect of the diets on the lower gastrointestinal microbiome. A differential representation analysis (analogous to differential expression in RNA sequencing) showed significant overlap in the contigs (which are genome fragments representing different microorganism species) that were differentially represented between experiments. These similarities suggest that, despite the different additives used, the 2 diets assessed in this investigation altered the microbiomes of the samples in similar ways. Contigs that were differentially represented in both experiments were tested for associations with methane production in an independent set of animals. These animals were not treated with a methane-mitigating diet, but did show substantial natural variation in methane emission levels. The contigs that were significantly differentially represented in response to both dietary additives showed a significant enrichment for associations with methane production. This suggests that these

  13. Highly Reflective Roofing Sheets Installed on a School Building to Mitigate the Urban Heat Island Effect in Osaka

    Directory of Open Access Journals (Sweden)

    Jihui Yuan


    Full Text Available Currently, strategies to mitigate urban heat island (UHI effects and reduce building energy consumption are implemented worldwide. In Japan, as an effective means of mitigating UHI effects and saving energy of buildings, highly reflective (HR roofs have increasingly been used. In this study, in order to evaluate the effect of HR roofs on building energy conservation, we investigated the solar reflectivity of a subject school roof in Osaka, Japan, in which HR roofing sheets were installed on the roof from 2010. Additionally, monthly and annual thermal loads, including the cooling load and heating load of the top floor of the school, were calculated using the thermal load calculation software New HASP/ACLD-β. Comparing the calculated thermal loads of the school after HR roofing sheet installation to before, the annual thermal load decreased about 25 MJ/m2/year, and the cooling load decreased about 112 MJ/m2/year. However, the heating load increased about 87 MJ/m2/year in winter. To minimize the annual thermal load, thermal insulation of the roof was also considered to be used together with HR roofing sheets. Thermal load calculations showed that the combination of HR roofing sheets and thermal insulation can be effective in further reducing the annual thermal load.

  14. Mitigation costs, distributional effects, and ancillary benefits of carbon policies in the Nordic countries, the U.K., and Ireland

    Energy Technology Data Exchange (ETDEWEB)

    Bye, B; Rosendahl, K.E. [Research Department, Statistics Norway, P.O. Box 8131 Dep., 0033 Oslo (Norway); Kverndokk, S. [Ragnar Frisch Centre for Economic Research, Gaustadalleen 21, 0349 Oslo (Norway)


    This paper provides a survey of top-down modelling analyses of carbon (C) abatement mitigation costs, distributional effects and ancillary benefits in the Nordic countries, the U.K. and Ireland. Special emphasis is placed on the effects of revenue recycling and tax exemptions. According to the analyses, modest emissions reductions can be met without substantial costs for the countries studied, and a strong double dividend is found in some analyses. The gross domestic product (GDP) or welfare effects are mostly in the range of -0.4 and 1.2% when C emissions are reduced by 20-30 per cent. Lowest costs are obtained without tax exemptions and with tax revenues used to reduce distortionary taxes. Ancillary benefits are mostly in the range 35-80/MgC{sup -1}, i.e., about the same order of magnitude as the mitigation costs. Distributional effects are mostly regressive, unless the tax revenues are distributed in lump-sum fashion with equal transfers to each household.

  15. Experimentation of several mitigation methods in Tasiujaq Airport to minimize the effects caused by the melting of permafrost

    DEFF Research Database (Denmark)

    Jørgensen, Anders Stuhr; Doré, Guy


    Since the beginning of the 1990s an important increase in the mean annual air temperatures has been recorded in Nunavik, Québec, Canada. This has lead to the degradation of permafrost, which is threatening the stability of airport and road embankments in the region. In the summer of 2007 a test......-site was established at Tasiujaq Airport to study the effect of three different mitigations methods: heat drain, air convection embankment, and gentle slope (8:1). The methods were constructed in the shoulder of the runway embankment, each method over a distance of 50 m. In each section thermistors were installed...

  16. Simulation study of HEMT structures with HfO2 cap layer for mitigating inverse piezoelectric effect related device failures

    Directory of Open Access Journals (Sweden)

    Deepthi Nagulapally


    Full Text Available The Inverse Piezoelectric Effect (IPE is thought to contribute to possible device failure of GaN High Electron Mobility Transistors (HEMTs. Here we focus on a simulation study to probe the possible mitigation of the IPE by reducing the internal electric fields and related elastic energy through the use of high-k materials. Inclusion of a HfO2 “cap layer” above the AlGaN barrier particularly with a partial mesa structure is shown to have potential advantages. Simulations reveal even greater reductions in the internal electric fields by using “field plates” in concert with high-k oxides.

  17. Biological seed priming mitigates the effects of water stress in sunflower seedlings. (United States)

    Singh, Narsingh Bahadur; Singh, Deepmala; Singh, Amit


    The sunflower (Helianthus annuus L. cv. PAC 36) seedlings were inoculated with plant growth promoting rhizobacteria (PGPR), viz. Azotobacter chroococcum (A+), Bacillus polymyxa (B+), separately and in combination of the two (AB+). Relative water content and seedling growth were maximum in AB+ seedlings under control. Water stress significantly decreased the RWC, growth and dry mass of non-inoculated seedlings. However, inoculated seedlings maintained higher growth even under water stress. Pigments and protein contents decreased under water stress, but higher amount of the same was observed in stressed AB+ seedlings. Enhanced activity of nitrate reductase was recorded in AB+ seedlings with maximum in control. Water stress significantly decreased the nitrate reductase activity. A significant increase in the activity of superoxide dismutase (SOD) in leaves was recorded under water stress except in B+ with maximum increase in non-inoculated seedlings. Catalase (CAT) activity decreased in stressed non-inoculated seedlings while increased in the leaves of A+ and AB+ seedlings. Almost similar trends were recorded for both leaves and cotyledons. PGPR improved the water status in stressed seedlings and thereby physiological and biochemical parameters and thus ameliorated the severe effects of water stress.

  18. Mitigating effect of Indian propolis against mitomycin C induced bone marrow toxicity. (United States)

    Kumari, Sandhya; Naik, Prashantha; Vishma, B L; Salian, Sujith Raj; Devkar, Raviraj Anand; Khan, Saleemulla; Mutalik, Srinivas; Kalthur, Guruprasad; Adiga, Satish Kumar


    A major drawback with cancer chemotherapy is its severe toxic effects on non-target tissues. Assessment of natural products for their protective effect against anticancer drugs-induced toxicity is gaining importance in cancer biology. The present study was aimed at assessing the protective effect of hydroethanolic extract of Indian propolis (HEIP) against mitomycin C (MMC)-induced genotoxicity and cytotoxicity. Swiss albino mice were injected with various doses of HEIP (100, 200, 300, 400, 600 and 800 mg/kg b. wt., i.p) 1 h prior to MMC (8 mg/kg, i.p.) injection. The geno- and cyto-toxicities were evaluated in mice by performing bone marrow micronucleus and TUNEL assays. In vitro antioxidant and lipid peroxidation inhibitory assays were carried out to understand the mechanism of the protective effects. The significant increase in the frequency of micronculeated cells (12.51 ± 0.48), apoptotic cells (23.43 ± 1.86) and reduction in P/N ratio (0.69 ± 0.04) compared with control indicated the potential geno- and cytotoxic effects of MMC in bone marrow. Pretreatment with HEIP resulted in the significant recovery of the toxic effects induced by MMC. HEIP at 400 mg/kg b. wt. was found to be the optimum dose imparting the maximum protective effects. The in vitro antioxidant and lipid peroxidation inhibitory assays suggest that the extract possesses substantial free radical scavenging activities. In conclusion, HEIP possesses substantial geno- and cyto-protective properties against MMC, which could be mediated through efficient free radical scavenging and inhibitory effect on lipid peroxidation.

  19. Status of R&D on mitigating the effects of pressure waves for the Spallation Neutron Source mercury target (United States)

    Riemer, Bernard W.; Wendel, Mark W.; Felde, David K.; Abdou, Ashraf A.; McClintock, David A.


    The Spallation Neutron Source (SNS) at the Oak Ridge National Laboratory has been conducting R&D on mitigating the effects of pressure waves in mercury spallation targets since 2001. More precisely, cavitation damage of the target vessel caused by the short beam pulse threatens to limit its lifetime more severely than radiation damage as well as limit its ultimate power capacity - and hence its neutron intensity performance. The R&D program has moved from verification of the beam-induced damage phenomena to study of material and surface treatments for damage resistance to the current emphasis on gas injection techniques for damage mitigation. Two techniques are being worked on: injection of small dispersed gas bubbles that mitigate the pressure waves volumetrically; and protective gas walls that isolate the vessel from the damaging effects of collapsing cavitation bubbles. The latter has demonstrated good damage mitigation during in-beam testing with limited pulses, and adequate gas wall coverage at the beam entrance window has been demonstrated with the SNS mercury target flow configuration using a full scale mercury test loop. A question on the required area coverage remains which depends on results from SNS target post irradiation examination. The small gas bubble technique has been less effective during past in-beam tests but those results were with un-optimized and un-verified bubble populations. Another round of in-beam tests with small gas bubbles is planned for 2011. The first SNS target was removed from service in mid 2009 and samples were cut from two locations at the target's beam entrance window. Through-wall damage was observed at the innermost mercury vessel wall (not a containment wall). The damage pattern suggested correlation with the local mercury flow condition which is nearly stagnant at the peak damage location. Detailed post irradiation examination of the samples is under way that will assess the erosion and measure irradiation-induced changes

  20. Impacts of greenhouse and local gases mitigation options on air pollution in the Buenos Aires Metropolitan Area: Valuation of human health effects


    Conte Grand, Mariana; Gaioli, Fabián; Perone, Elizabeth; Sörensson, Anna; Svensson, Tomas; Tarela, Pablo


    The objective of this work is to assess through the "avoided health cost method" what would be the economic benefits of undertaking greenhouse (and local) gases mitigation policies in the Buenos Aires Metropolitan Area. To do so, we have developed six steps: Mitigation Scenarios (which policies to undertake), Emissions Inventory according to those, an Ambient Air Pollution Model to calculate the physical impacts, Health Effects Estimation to assess the health consequences of reducing air poll...

  1. Quantifying the effectiveness of climate change mitigation through forest plantations and carbon sequestration with an integrated land-use model

    Directory of Open Access Journals (Sweden)

    Swart Rob J


    Full Text Available Abstract Background Carbon plantations are introduced in climate change policy as an option to slow the build-up of atmospheric carbon dioxide (CO2 concentrations. Here we present a methodology to evaluate the potential effectiveness of carbon plantations. The methodology explicitly considers future long-term land-use change around the world and all relevant carbon (C fluxes, including all natural fluxes. Both issues have generally been ignored in earlier studies. Results Two different baseline scenarios up to 2100 indicate that uncertainties in future land-use change lead to a near 100% difference in estimates of carbon sequestration potentials. Moreover, social, economic and institutional barriers preventing carbon plantations in natural vegetation areas decrease the physical potential by 75–80% or more. Nevertheless, carbon plantations can still considerably contribute to slowing the increase in the atmospheric CO2 concentration but only in the long term. The most conservative set of assumptions lowers the increase of the atmospheric CO2 concentration in 2100 by a 27 ppm and compensates for 5–7% of the total energy-related CO2 emissions. The net sequestration up to 2020 is limited, given the short-term increased need for agricultural land in most regions and the long period needed to compensate for emissions through the establishment of the plantations. The potential is highest in the tropics, despite projections that most of the agricultural expansion will be in these regions. Plantations in high latitudes as Northern Europe and Northern Russia should only be established if the objective to sequester carbon is combined with other activities. Conclusion Carbon sequestration in plantations can play an important role in mitigating the build-up of atmospheric CO2. The actual magnitude depends on natural and management factors, social barriers, and the time frame considered. In addition, there are a number of ancillary benefits for local

  2. Review: Soil management in mitigating the adverse effects of climate change

    Directory of Open Access Journals (Sweden)

    Aman Ullah BhattI


    Full Text Available Emission of Green House Gases (GHGs from various sources into the atmosphere causes rise in air temperature. This addition of GHGs has a great impact on the environment. Among the GHGs, carbon dioxide (CO2 is the major contributor. A variety of options exists for mitigation of GHGs emissions in agriculture. The most prominent options are improved soil management practices viz. integrated plant nutrient management, precision agriculture (variable rate fertilizer technology, use of nitrification inhibitors, crop residue management, moisture restoration and restoration of crop productivity of degraded lands, which increase crop production per unit area, enhancing crop production and withdraw atmospheric CO2 through enhanced photosynthesis. This paper shows that such improved soil management practices can restore the crop productivity of marginal lands and purify the air by withdrawing atmospheric CO2.

  3. Effect of Wind Intermittency on the Electric Grid: Mitigating the Risk of Energy Deficits

    CERN Document Server

    George, Sam O; Nguyen, Scott V


    Successful implementation of California's Renewable Portfolio Standard (RPS) mandating 33 percent renewable energy generation by 2020 requires inclusion of a robust strategy to mitigate increased risk of energy deficits (blackouts) due to short time-scale (sub 1 hour) intermittencies in renewable energy sources. Of these RPS sources, wind energy has the fastest growth rate--over 25% year-over-year. If these growth trends continue, wind energy could make up 15 percent of California's energy portfolio by 2016 (wRPS15). However, the hour-to-hour variations in wind energy (speed) will create large hourly energy deficits that require installation of other, more predictable, compensation generation capacity and infrastructure. Compensating for the energy deficits of wRPS15 could potentially cost tens of billions in additional dollar-expenditure for fossil and / or nuclear generation capacity. There is a real possibility that carbon dioxide and other greenhouse gas (GHG) emission reductions will miss the California ...

  4. Effects of climate uncertainties on welfare optimal investment streams into mitigation technologies (United States)

    Held, H.; Kriegler, E.; Lessmann, K.; Lorenz, A.


    We discuss a stylised portfolio of climate change mitigation options and ask the following question: what is the intertemporally optimal mix of these options under the boundary condition of a climate guardrail and uncertainty about the temperature response to rising carbon dioxide concentrations? We impose a guardrail that requires the increase of global mean temperature T to be limited to 2K with at least a minimum probability P (e.g., P=0.75). The uncertainty about the temperature response is captured by a PDF for climate sensitivity and ocean heat uptake. For economic optimisation, we use an ensemble-version of the growth model MIND [1]. As a key results we show that robust climate protection paths will require aggressive mitigation measures [2]. In this context it is also possible to ask for the economic potential of reducing uncertainty in climate sensitivity [3] and ocean heat uptake [4] that is generically by orders of magnitude larger than the costs induced by the related research programmes. References [1] O. Edenhofer., N. Bauer, E. Kriegler: The Impact of Technological Change on Climate Protection and Welfare: Insights from the Model MIND. Ecological Economics, 54 (2-3): 277-292 (2005). [2] H. Held, E. Kriegler, K. Lessmann, O. Edenhofer, Efficient Climate Policies under Technology and Climate Uncertainty, Energy Economics, in press. [3] T. Schneider von Deimling, H. Held, A. Ganopolski, S. Rahmstorf, Climate sensitivity estimated from ensemble simulations of glacial climates, Climate Dynamics 27, 149-163, DOI 10.1007/s00382-006-0126-8 (2006). [4] A. Lorenz, Diploma Thesis, U Potsdam (2007).

  5. Comparison Between Mitigation Effects of the Finite Larmor Radius and Sheared Axial Flow on Rayleigh-Taylor Instability in Z-Pinch implosions

    Institute of Scientific and Technical Information of China (English)

    邱孝明; 黄林; 简广德


    A magnetohydrodynamic (MHD) formulation is derived to investigate and compare the mitigation effects of both the sheared axial flow and finite Larmor radius (FLR) on the Rayleigh-Taylor (RT) instability in Z-pinch implosions. The sheared axial flow is introduced into MHD equations in a conventional way and the FLR effect into the equations via а/аt → -i(ω + ik2⊥ρi2Ωi), as proposed in our previous paper [Chin. Phys. Lett. 2002, 19:217] , where k2⊥ρ2i is referred to FLR effect from the general kinetic theory of magnetized plasma. Therefore the linearized continuity and momentum equations for the perturbed massdensity and velocity include both the sheared axial flow and the FLR effect. It is found that the effect of sheared axial flow with a lower peak velocity can mitigate RT instability in the whole wavenumber region and the effect of sheared axial flow with a higher one can mitigate RT instability only in the large wavenumber region (for normalized wavenumber κ> 2.4); The effect of FLR can mitigate RT instability in the whole wavenumber region and the mitigation effect is stronger than that of the sheared axial flow with a lower peak velocity in the almost whole wavenumber region.

  6. The Effectiveness of High Quality Supplementary Cementitious Materials for Mitigating ASR Expansion in Concrete with High Alkali Content

    Directory of Open Access Journals (Sweden)

    I. Prasetia


    Full Text Available Alkali silica reaction (ASR is influenced by external factors such as the surrounding environment of high alkalinity. Countries with cold climate have a high probability to be exposed to high concentrations of NaCl solution by the deicing salt. This condition will lead to serious ASR problems in concrete, if the aggregates contain reactive silica. The main research work in this paper is to investigate the effect of 15% replacement ratio of high quality fine fly ash (FA15% and 42% replacement ratio of blast furnace slag (BFS42% on the ASR mitigation in concrete with different alkali amount inside the pore solution. The experiments were conducted according to the accelerated mortar bars experiment following the JIS A1146 mortar bar test method. In addition, post-analysis such as observation of ASR gel formation by the Uranyl Acetate Fluorescence Method and observation of thin sections using a Polarizing Microscope were also conducted. The mortar bar tests show a very good mitigation effect of supplementary cementitious materials (SCMs. The results show that only small ASR expansions, which can be categorized as “innocuous”, occurred for specimens with 1.2% Na2Oeq using FA15% and BFS42%. However, larger alkali amount inside the system will require more SCMs amount.

  7. Contribution of forests and forestry to mitigation of greenhouse effects in Greece. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland. 28-30 Sep 2000

    Directory of Open Access Journals (Sweden)

    Radoglou, K.


    Full Text Available In Greece, there is no official inventory for the activity land use, land use change and forestry. The national forest inventory was completed in 1992. Using the data of this inventory, the carbon store of woody biomass of Greece has been estimated by FAO-TBFRA (2000 as 52.04 millions t C, of which 46.36 millions t C is above stump biomass and 8.67 millions t C is stump and root biomass. The four highest priority mitigation options in the forestry sector in Greece are afforestation and reforestation; forest management improvements; protection of existing forests from forest fires and human pressure and substitution of fossil fuels with sustainably produced biofuel.


    Energy Technology Data Exchange (ETDEWEB)

    Terry Brown; Song Jin


    Reclaimed mine lands have the potential to sequester carbon. The use of amendments to increase fertility and overall soil quality is encouraging. Waste amendments such as sewage sludge and clarifier sludge, as well as commercial compost were tested to determine their effects on carbon sequestration and humic acid formation in reclaimed mine lands. Sewage sludge and clarifier sludge have the potential to work as reclaimed mine lands amendments. C:N ratios need to be understood to determine probability of nutrient leaching and water contamination. Microbial activity on the humic acid fraction of sludge is directed toward the readily degradable constituents containing single chain functional groups. This finding indicate that amendments with lower molecular constituents such as aliphatic compounds are more amenable to microbial degradation, therefore serves as better nutrient sources to enhance the formation of vegetation in mine lands and leads to more efficient carbon sequestration.

  9. Neuromodulatory Effects of Hesperidin in Mitigating Oxidative Stress in Streptozotocin Induced Diabetes

    Directory of Open Access Journals (Sweden)

    Mohammad Ashafaq


    Full Text Available Oxidative stress has been implicated in pathogenesis of streptozotocin- (STZ- induced diabetes mellitus and its complication in central nervous system (CNS. Recent studies have provided insights on antioxidants and their emergence as potential therapeutic and nutraceutical. The present study examined the hypothesis that hesperidin (HP ameliorates oxidative stress and may be a limiting factor in the extent of CNS complication following diabetes. To test this hypothesis rats were divided into four groups: control, diabetic, diabetic-HP treated, and vehicle for HP treatment group. Diabetes mellitus was induced by a single injection of STZ (65 mg/kg body weight. Three days after STZ injection, HP was given (50 mg/kg b.wt. orally once daily for four weeks. The results of the present investigation suggest that the significant elevated levels of oxidative stress markers were observed in STZ-treated animals, whereas significant depletion in the activity of nonenzymatic antioxidants and enzymatic antioxidants was witnessed in diabetic rat brain. Neurotoxicity biomarker activity was also altered significantly. HP treatment significantly attenuated the altered levels of oxidative stress and neurotoxicity biomarkers. Our results demonstrate that HP exhibits potent antioxidant and neuroprotective effects on the brain tissue against the diabetic oxidative damage in STZ-induced rodent model.

  10. Effects of vegetation on debris flow mitigation: A case study from Gansu province, China (United States)

    Wang, Siyuan; Meng, Xingmin; Chen, Guan; Guo, Peng; Xiong, Muqi; Zeng, Runqiang


    Debris flows are traditionally controlled using civil engineering structures such as check dams. However, the misuse of such strategies may sometimes trigger environmental hazards such as the catastrophic landslide in 2010 in Zouqu county, China, and therefore other methods such as the use of vegetation as an eco-engineering tool are increasingly being adopted. The aim of the present research was to investigate the bioengineering effects of vegetation over time in an area prone to debris flows in Gansu province, China. We collected detailed data from 2012 to 2014 on vegetation type, density, and root system morphology, and measured profiles across the valley. In addition, we assessed the increased soil cohesion provided by the root development of three monospecific stands of Robinia pseudoacacia of different ages growing within the debris valley, and on a larger scale, their effects on channel morphology. These data were incorporated into a modified form of BSTEM (Bank Stability and Toe Erosion Model) and a cellular braided-stream model. The results indicate that with increasing age, the FOS (factor of safety) of the bank would be significantly increased, and that the flooded area in the valley caused by simulated flood events would be decreased by 18-24%, on average. Subsequently, field data were incorporated into a cellular model to simulate sediment movement and the effects of vegetation on the channel dynamics. The results demonstrate that the stability provided by vegetation could result in a less active valley system and that overall the development of debris-controlling vegetation could make a major contribution to ecosystem restoration. However, careful management is essential for making optimum use of the vegetation.

  11. Enhanced processing in arrays of optimally tuned nonlinear biomimetic sensors: A coupling-mediated Ringelmann effect and its dynamical mitigation (United States)

    Nikitin, Alexander P.; Bulsara, Adi R.; Stocks, Nigel G.


    Inspired by recent results on self-tunability in the outer hair cells of the mammalian cochlea, we describe an array of magnetic sensors where each individual sensor can self-tune to an optimal operating regime. The self-tuning gives the array its "biomimetic" features. We show that the overall performance of the array can, as expected, be improved by increasing the number of sensors but, however, coupling between sensors reduces the overall performance even though the individual sensors in the system could see an improvement. We quantify the similarity of this phenomenon to the Ringelmann effect that was formulated 103 years ago to account for productivity losses in human and animal groups. We propose a global feedback scheme that can be used to greatly mitigate the performance degradation that would, normally, stem from the Ringelmann effect.

  12. 32 CFR 651.15 - Mitigation and monitoring. (United States)


    ... uncertain (for example, new technology); (3) Major environmental controversy remains associated with the... an integral part of any mitigation system. (1) Enforcement monitoring ensures that mitigation is... effect of the mitigation. In establishing the monitoring system, the responsible agent should...

  13. Effects of Formulation on Microbicide Potency and Mitigation of the Development of Bacterial Insusceptibility. (United States)

    Cowley, Nicola L; Forbes, Sarah; Amézquita, Alejandro; McClure, Peter; Humphreys, Gavin J; McBain, Andrew J


    Risk assessments of the potential for microbicides to select for reduced bacterial susceptibility have been based largely on data generated through the exposure of bacteria to microbicides in aqueous solution. Since microbicides are normally formulated with multiple excipients, we have investigated the effect of formulation on antimicrobial activity and the induction of bacterial insusceptibility. We tested 8 species of bacteria (7 genera) before and after repeated exposure (14 passages), using a previously validated gradient plating system, for their susceptibilities to the microbicides benzalkonium chloride, benzisothiozolinone, chlorhexidine, didecyldimethyl ammonium chloride, DMDM-hydantoin, polyhexamethylene biguanide, thymol, and triclosan in aqueous solution (nonformulated) and in formulation with excipients often deployed in consumer products. Susceptibilities were also assessed following an additional 14 passages without microbicide to determine the stability of any susceptibility changes. MICs and minimum bactericidal concentrations (MBC) were on average 11-fold lower for formulated microbicides than for nonformulated microbicides. After exposure to the antimicrobial compounds, of 72 combinations of microbicide and bacterium there were 19≥4-fold (mean, 8-fold) increases in MIC for nonformulated and 8≥4-fold (mean, 2-fold) increases in MIC for formulated microbicides. Furthermore, there were 20≥4-fold increases in MBC (mean, 8-fold) for nonformulated and 10≥4-fold (mean, 2-fold) increases in MBC for formulated microbicides. Susceptibility decreases fully or partially reverted back to preexposure values for 49% of MICs and 72% of MBCs after further passage. In summary, formulated microbicides exhibited greater antibacterial potency than unformulated actives and susceptibility decreases after repeated exposure were lower in frequency and extent.

  14. High Spatial Resolution Thermal Remote Sensing of the Urban Heat Island Effect: Assessment of Risks to Human Health and Development of Mitigation Strategies for Sustainable Cities (United States)

    Quattrochi, Dale A.; Luvall, Jeffrey C.; Rickman, Douglas L.; Estes, Maurice G., Jr.; Laymon, Charles A.; Crosson, William; Howell, Burgess F.; Gillani, Noor V.; Arnold, James E. (Technical Monitor)


    The growth of cities, both in population and in areal extent, appears as an inexorable process. Urbanization continues at a rapid rate, and it is estimated that by the year 2025, 80% of the world's population will live in cities. One of the more egregious side effects of urbanization is the deterioration in air quality as a result of increased vehicular traffic, industrialization and related activities. In the United States alone, under the more stringent air quality guidelines established by the U.S. Environmental Protection Agency (EPA) in 1997, nearly 300 counties in 34 states will not meet the new air quality standards for ground level ozone. The mitigation of one the physical/environmental characteristics of urbanization known as the urban heat island (UHI) effect, is now being looked at more closely as a possible way to bring down ground level ozone levels in cities and assist states in improving air quality. The UHI results from the replacement of "natural" land covers (e.g., trees, grass) with urban land surface types, such as pavement and buildings. Heat stored in these surfaces is released into the air and results in a "dome" of elevated air temperatures that presides over cities. The effect of this dome of elevated air temperatures is known as the UHI, which is most prevalent about 2-3 hours after sunset on days with intense solar radiation and calm winds. Given the local and regional impacts of the UHI, there are significant potential affects on human health, particularly as related to heat stress and ozone on body temperature regulation and on the cardiovascular and respiratory systems. In this study we are using airborne and satellite remote sensing data to analyze how differences in the urban landscape influence or drive the development of the UHI over four U.S. cities. Additionally, we are assessing what the potential impact is on risks to human health, and developing mitigation strategies to make urban areas more environmentally sustainable.

  15. Remote Sensing of the Urban Heat Island Effect: Assessment of Risks to Human Health and Development of Mitigation Strategies for Sustainable Cities (United States)

    Quattrochi, Dale A.; Luvall, Jeffrey C.; Rickman, Douglas L.; Estes, Maurice G., Jr.; Laymon, Charles A.; Crosson, William; Howell, Burgess F.; Gillani, Noor V.; Arnold, James E. (Technical Monitor)


    The growth of cities, both in population and in areal extent, appears as an inexorable process. Urbanization continues at a rapid rate, and it is estimated that by the year 2025, 80% of the world's population will live in cities. One of the more egregious side effects of urbanization is the deterioration in air quality as a result of increased vehicular traffic, industrialization and related activities. In the United States alone, under the more stringent air quality guidelines established by the U.S. Environmental Protection Agency (EPA) in 1997, nearly 300 counties in 34 states will not meet the new air quality standards for ground level ozone. The mitigation of one the physical/environmental characteristics of urbanization known as the urban heat island (UHI) effect, is now being looked at more closely as a possible way to bring down ground level ozone levels in cities and assist states in improving air quality. The UHI results from the replacement of "natural" land covers (e.g., trees, grass) with urban land surface types, such as pavement and buildings. Heat stored in these surfaces is released into the air and results in a "dome" of elevated air temperatures that presides over cities. The effect of this dome of elevated air temperatures is known as the UHI, which is most prevalent about 2-3 hours after sunset on days with intense solar radiation and calm winds. Given the local and regional impacts of the UHI, there are significant potential affects on human health, particularly as related to heat stress and ozone on body temperature regulation and on the cardiovascular and respiratory systems. In this study we are using airborne and satellite remote sensing data to analyze how differences in the urban landscape influence or drive the development of the UHI over four U.S. cities. Additionally, we are assessing what the potential impact is on risks to human health, and developing mitigation strategies to make urban areas more environmentally sustainable.

  16. Quantifying process-based mitigation strategies in historical context: separating multiple cumulative effects on river meander migration.

    Directory of Open Access Journals (Sweden)

    Alexander K Fremier

    Full Text Available Environmental legislation in the US (i.e. NEPA requires defining baseline conditions on current rather than historical ecosystem conditions. For ecosystems with long histories of multiple environmental impacts, this baseline method can subsequently lead to a significantly altered environment; this has been termed a 'sliding baseline'. In river systems, cumulative effects caused by flow regulation, channel revetment and riparian vegetation removal significantly impact floodplain ecosystems by altering channel dynamics and precluding subsequent ecosystem processes, such as primary succession. To quantify these impacts on floodplain development processes, we used a model of river channel meander migration to illustrate the degree to which flow regulation and riprap impact migration rates, independently and synergistically, on the Sacramento River in California, USA. From pre-dam conditions, the cumulative effect of flow regulation alone on channel migration is a reduction by 38%, and 42-44% with four proposed water diversion project scenarios. In terms of depositional area, the proposed water project would reduce channel migration 51-71 ha in 130 years without current riprap in place, and 17-25 ha with riprap. Our results illustrate the utility of a modeling approach for quantifying cumulative impacts. Model-based quantification of environmental impacts allow scientists to separate cumulative and synergistic effects to analytically define mitigation measures. Additionally, by selecting an ecosystem process that is affected by multiple impacts, it is possible to consider process-based mitigation scenarios, such as the removal of riprap, to allow meander migration and create new floodplains and allow for riparian vegetation recruitment.

  17. Carbon dioxide enrichment: a technique to mitigate the negative effects of salinity on the productivity of high value tomatoes

    Directory of Open Access Journals (Sweden)

    Maria J. Sánchez-González


    Full Text Available The present study was conducted to determine the mitigating influence of greenhouse CO2 enrichment on the negative effects of salinity in Mediterranean conditions. Hybrid Raf (cv. Delizia tomato plants were exposed to two salinity levels of the nutrient solution (5 and 7 dS/m obtained by adding NaCl, and two CO2 concentrations (350 and 800 μmol/mol in which CO2 enrichment was applied during the daytime according to a strategy linked to ventilation. Increasing water salinity negatively affected the leaf area index (LAI, the specific leaf area (SLA, the water use efficiency (WUE, the radiation use efficiency (RUE and dry weight (DW accumulation resulting in lower marketable yield. The high salinity treatment (7 dS/m increased fruit firmness (N, total soluble solids content (SSC and titratable acidity (TA, whereas pH was reduced in the three ripening stages: mature green/breaker (G, turning (T, and pink/light red (P. Also, the increase in electrical conductivity of the nutrient solution led to a general change in intensity of the sensory characteristics of tomato fruits. On the other hand, CO2 enrichment did not affect LAI although SLA was reduced. RUE and DW accumulation were increased resulting in higher marketable yield, through positive effects on fruit number and their average weight. WUE was enhanced by CO2 supply mainly through increased growth and yield. Physical-chemical quality parameters such as fruit firmness, TA and pH were not affected by CO2 enrichment whereas SSC was enhanced. Greenhouse CO2 enrichment did mitigate the negative effect of saline conditions on productivity without compromising organoleptic and sensory fruit quality.

  18. Carbon dioxide enrichment: a technique to mitigate the negative effects of salinity on the productivity of high value tomatoes

    Energy Technology Data Exchange (ETDEWEB)

    Sánchez-González, M. J.; Sánchez-Guerrero, M.C.; Medrano, E.; Porras, M.E.; Baeza, E.J.; Lorenzo, P.


    The present study was conducted to determine the mitigating influence of greenhouse CO2 enrichment on the negative effects of salinity in Mediterranean conditions. Hybrid Raf (cv. Delizia) tomato plants were exposed to two salinity levels of the nutrient solution (5 and 7 dS/m) obtained by adding NaCl, and two CO2 concentrations (350 and 800 μmol/mol) in which CO2 enrichment was applied during the daytime according to a strategy linked to ventilation. Increasing water salinity negatively affected the leaf area index (LAI), the specific leaf area (SLA), the water use efficiency (WUE), the radiation use efficiency (RUE) and dry weight (DW) accumulation resulting in lower marketable yield. The high salinity treatment (7 dS/m) increased fruit firmness (N), total soluble solids content (SSC) and titratable acidity (TA), whereas pH was reduced in the three ripening stages: mature green/breaker (G), turning (T), and pink/light red (P). Also, the increase in electrical conductivity of the nutrient solution led to a general change in intensity of the sensory characteristics of tomato fruits. On the other hand, CO2 enrichment did not affect LAI although SLA was reduced. RUE and DW accumulation were increased resulting in higher marketable yield, through positive effects on fruit number and their average weight. WUE was enhanced by CO2 supply mainly through increased growth and yield. Physical-chemical quality parameters such as fruit firmness, TA and pH were not affected by CO2 enrichment whereas SSC was enhanced. Greenhouse CO2 enrichment did mitigate the negative effect of saline conditions on productivity without compromising organoleptic and sensory fruit quality. (Author)

  19. Defining operating rules for mitigation of drought effects on water supply systems (United States)

    Rossi, G.; Caporali, E.; Garrote, L.; Federici, G. V.


    Reservoirs play a pivotal role for water supply systems regulation and management especially during drought periods. Optimization of reservoir releases, related to drought mitigation rules is particularly required. The hydrologic state of the system is evaluated defining some threshold values, expressed in probabilistic terms. Risk deficit curves are used to reduce the ensemble of possible rules for simulation. Threshold values can be linked to specific actions in an operational context in different levels of severity, i.e. normal, pre-alert, alert and emergency scenarios. A simplified model of the water resources system is built to evaluate the threshold values and the management rules. The threshold values are defined considering the probability to satisfy a given fraction of the demand in a certain time horizon, and are validated with a long term simulation that takes into account the characteristics of the evaluated system. The threshold levels determine some curves that define reservoir releases as a function of existing storage volume. A demand reduction is related to each threshold level. The rules to manage the system in drought conditions, the threshold levels and the reductions are optimized using long term simulations with different hypothesized states of the system. Synthetic sequences of flows with the same statistical properties of the historical ones are produced to evaluate the system behaviour. Performances of different values of reduction and different threshold curves are evaluated using different objective function and performances indices. The methodology is applied to the urban area Firenze-Prato-Pistoia in central Tuscany, in Central Italy. The considered demand centres are Firenze and Bagno a Ripoli that have, accordingly to the census ISTAT 2001, a total of 395.000 inhabitants.

  20. Tsunami mitigation and preparedness activities in California: Chapter L in The SAFRR (Science Application for Risk Reduction) Tsunami Scenario (United States)

    Wilson, Rick; Miller, Kevin H.


    Scenario planning and final results associated with the U.S. Geological Survey Science Application for Risk Reduction (SAFRR) tsunami project are providing great benefits to the ongoing tsunami risk-reduction efforts of the California Tsunami Preparedness and Hazard Mitigation Program. This program, led by the California Governor’s Office of Emergency Services and the California Geological Survey, works with coastal communities to improve tsunami preparedness and mitigation at the local level through various efforts, such as improving tsunami hazard analysis, establishing consistent evacuation communications and planning, and leveraging national risk-reduction efforts associated with the National Tsunami Hazard Mitigation Program. The recent 2010 Chilean and 2011 Tohoku tsunamis did not cause notable inundation of dry land in California, but dozens of harbors sustained damages totaling nearly $100 million (Wilson and others, 2012a). Estimates associated with the SAFRR distant tsunami scenario suggest socioeconomic and environmental losses could be even larger. Information gathered from these events and the SAFRR scenario is guiding the development and implementation of new strategies for emergency response, maritime planning, and land-use planning, including a reassessment of the tsunami threat along the California coast;

  1. Assessing the bio-mitigation effect of integrated multi-trophic aquaculture on marine environment by a numerical approach. (United States)

    Zhang, Junbo; Kitazawa, Daisuke


    With increasing concern over the aquatic environment in marine culture, the integrated multi-trophic aquaculture (IMTA) has received extensive attention in recent years. A three-dimensional numerical ocean model is developed to explore the negative impacts of aquaculture wastes and assess the bio-mitigation effect of IMTA systems on marine environments. Numerical results showed that the concentration of surface phytoplankton could be controlled by planting seaweed (a maximum reduction of 30%), and the percentage change in the improvement of bottom dissolved oxygen concentration increased to 35% at maximum due to the ingestion of organic wastes by sea cucumbers. Numerical simulations indicate that seaweeds need to be harvested in a timely manner for maximal absorption of nutrients, and the initial stocking density of sea cucumbers >3.9 individuals m(-2) is preferred to further eliminate the organic wastes sinking down to the sea bottom.

  2. Regional climate change mitigation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Rowlands, Ian H. [UNEP Collaborating Centre on Energy and Environment, and Univ. of Waterloo (Canada)


    The purpose of this paper is to explore some of the key methodological issues that arise from an analysis of regional climate change mitigation options. The rationale for any analysis of regional mitigation activities, emphasising both the theoretical attractiveness and the existing political encouragement and the methodology that has been developed are reviewed. The differences arising from the fact that mitigation analyses have been taken from the level of the national - where the majority of the work has been completed to date - to the level of the international - that is, the `regional` - will be especially highlighted. (EG)


    Directory of Open Access Journals (Sweden)

    Ondieki Gekara


    Full Text Available The objective of this study was to research nutritional strategies to mitigate the effects of Negative Energy Balance (NEB on reproductive performance of early postpartum does. Twenty seven does in their second week of lactation and their kids were randomly assigned to three levels of supplement diet, replicated three times. The diets were: (1 Low Energy/Protein supplement level (LEP; Control, (2 Medium Energy/Protein supplement level (MEP, or (3 High Energy/Protein supplement level (HEP. The LEP (control diet was fed at 0.95%, MEP at 1.50% and HEP at 1.90% of BW on a DM basis. The study lasted 28 days. Supplement level did not (p>0.10 reverse the expected loss in doe body condition during the early stages of lactation. The does lost on average 0.056 kg day-1 through the duration of the study. The average body condition score of the does at the start of the experiment was 1.80 (on a scale of 1-5 and 1.75 at the end. The HEP kids tended (p0.10 between HEP and MEP or MEP and LEP kids. The HEP kids gained 0.087 kg day-1; MEP kids gained 0.061 kg day-1 whereas LEP kids gained 0.022 kg day-1. In conclusion, something in addition to high energy/protein supplement level may be needed to mitigate the effects of NEB which is in part responsible for delayed return of ovulatory events in early postpartum does.

  4. Multi-resolution statistical image reconstruction for mitigation of truncation effects: application to cone-beam CT of the head (United States)

    Dang, Hao; Webster Stayman, J.; Sisniega, Alejandro; Zbijewski, Wojciech; Xu, Jennifer; Wang, Xiaohui; Foos, David H.; Aygun, Nafi; Koliatsos, Vassilis E.; Siewerdsen, Jeffrey H.


    A prototype cone-beam CT (CBCT) head scanner featuring model-based iterative reconstruction (MBIR) has been recently developed and demonstrated the potential for reliable detection of acute intracranial hemorrhage (ICH), which is vital to diagnosis of traumatic brain injury and hemorrhagic stroke. However, data truncation (e.g. due to the head holder) can result in artifacts that reduce image uniformity and challenge ICH detection. We propose a multi-resolution MBIR method with an extended reconstruction field of view (RFOV) to mitigate truncation effects in CBCT of the head. The image volume includes a fine voxel size in the (inner) nontruncated region and a coarse voxel size in the (outer) truncated region. This multi-resolution scheme allows extension of the RFOV to mitigate truncation effects while introducing minimal increase in computational complexity. The multi-resolution method was incorporated in a penalized weighted least-squares (PWLS) reconstruction framework previously developed for CBCT of the head. Experiments involving an anthropomorphic head phantom with truncation due to a carbon-fiber holder were shown to result in severe artifacts in conventional single-resolution PWLS, whereas extending the RFOV within the multi-resolution framework strongly reduced truncation artifacts. For the same extended RFOV, the multi-resolution approach reduced computation time compared to the single-resolution approach (viz. time reduced by 40.7%, 83.0%, and over 95% for an image volume of 6003, 8003, 10003 voxels). Algorithm parameters (e.g. regularization strength, the ratio of the fine and coarse voxel size, and RFOV size) were investigated to guide reliable parameter selection. The findings provide a promising method for truncation artifact reduction in CBCT and may be useful for other MBIR methods and applications for which truncation is a challenge.

  5. Cross-sectoral assessment of mitigation options

    DEFF Research Database (Denmark)

    Halsnæs, K.


    The paper addresses the relationship between national economic and social development objectives and climate change mitigation, with national studies for Tanzania and Zimbabwe as the starting point. The main activities driving GHG emissions in these countries are evaluated in order to identify key...... options and polity areas where there may be synergistic effects between climate change mitigation and national development objectives, The country study for Tanzania has identified forestry and land use activities and the agricultural sectors as some of the main drivers in the future growth of greenhouse...... gas emissions, Forestry, land use and agriculture are at the same time key economic and social development areas, This means that options leading to improved performance of these activities can reduce future greenhouse gas emissions and imply increasing welfare, A potential for win-win options has...

  6. Image disparity in cross-spectral face recognition: mitigating camera and atmospheric effects (United States)

    Cao, Zhicheng; Schmid, Natalia A.; Li, Xin


    Matching facial images acquired in different electromagnetic spectral bands remains a challenge. An example of this type of comparison is matching active or passive infrared (IR) against a gallery of visible face images. When combined with cross-distance, this problem becomes even more challenging due to deteriorated quality of the IR data. As an example, we consider a scenario where visible light images are acquired at a short standoff distance while IR images are long range data. To address the difference in image quality due to atmospheric and camera effects, typical degrading factors observed in long range data, we propose two approaches that allow to coordinate image quality of visible and IR face images. The first approach involves Gaussian-based smoothing functions applied to images acquired at a short distance (visible light images in the case we analyze). The second approach involves denoising and enhancement applied to low quality IR face images. A quality measure tool called Adaptive Sharpness Measure is utilized as guidance for the quality parity process, which is an improvement of the famous Tenengrad method. For recognition algorithm, a composite operator combining Gabor filters, Local Binary Patterns (LBP), generalized LBP and Weber Local Descriptor (WLD) is used. The composite operator encodes both magnitude and phase responses of the Gabor filters. The combining of LBP and WLD utilizes both the orientation and intensity information of edges. Different IR bands, short-wave infrared (SWIR) and near-infrared (NIR), and different long standoff distances are considered. The experimental results show that in all cases the proposed technique of image quality parity (both approaches) benefits the final recognition performance.

  7. Importance of composition and hygroscopicity of BC particles to the effect of BC mitigation on cloud properties: Application to California conditions (United States)

    Bahadur, Ranjit; Russell, Lynn M.; Jacobson, Mark Z.; Prather, Kimberly; Nenes, Athanasios; Adams, Peter; Seinfeld, John H.


    Black carbon (BC) has many effects on climate including the direct effect on atmospheric absorption, indirect and semi-direct effects on clouds, snow effects, and others. While most of these are positive (warming), the first indirect effect is negative and quantifying its magnitude in addition to other BC feedbacks is important for supporting policies that mitigate BC. We use the detailed aerosol chemistry parcel model of Russell and Seinfeld (1998), observationally constrained by initial measured aerosol concentrations from five California sites, to provide simulated cloud drop number (CDN) concentrations against which two GCM calculations - one run at the global scale and one nested from the global-to-regional scale are compared. The GCM results reflect the combined effects of their emission inventories, advection schemes, and cloud parameterizations. BC-type particles contributed between 16 and 20% of cloud droplets at all sites even in the presence of more hygroscopic particles. While this chemically detailed parcel model result is based on simplified cloud dynamics and does not consider semi-direct or cloud absorption effects, the cloud drop number concentrations are similar to the simulations of both Chen et al. (2010b) and Jacobson (2010) for the average cloud conditions in California. Reducing BC particle concentration by 50% decreased the cloud droplet concentration by between 6% and 9% resulting in the formation of fewer, larger cloud droplets that correspond to a lower cloud albedo. This trend is similar to Chen et al. (2010b) and Jacobson (2010) when BC particles were modeled as hygroscopic. This reduction in CDN in California due to the decrease in activated BC particles supports the concern raised by Chen et al. (2010a) that the cloud albedo effect of BC particles has a cooling effect that partially offsets the direct forcing reduction if other warming effects of BC on clouds are unchanged. These results suggests that for regions like the California

  8. Neurotoxin Mitigation (United States)


    methylglyoxal involved in ligand binding and esterase activity. J Biol Chem 280:5724-5732. Benschop HP and Keijer JH (1966) On the mechanism of ageing of...identiWes hotspot site of modiWcation in human serum albumin by methylglyoxal involved in ligand binding and esterase activity, J. Biol. Chem. 280 (2005

  9. Long-term development and effectiveness of private flood mitigation measures: an analysis for the German part of the river Rhine (United States)

    Bubeck, P.; Botzen, W. J. W.; Kreibich, H.; Aerts, J. C. J. H.


    Flood mitigation measures implemented by private households have become an important component of contemporary integrated flood risk management in Germany and many other countries. Despite the growing responsibility of private households to contribute to flood damage reduction by means of private flood mitigation measures, knowledge on the long-term development of such measures, which indicates changes in vulnerability over time, and their effectiveness, is still scarce. To gain further insights into the long-term development, current implementation level and effectiveness of private flood mitigation measures, empirical data from 752 flood-prone households along the German part of the Rhine are presented. It is found that four types of flood mitigation measures developed gradually over time among flood-prone households, with severe floods being important triggers for an accelerated implementation. At present, still a large share of respondents has not implemented a single flood mitigation measure, despite the high exposure of the surveyed households to floods. The records of household's flood damage to contents and structure during two consecutive flood events with similar hazard characteristics in 1993 and 1995 show that an improved preparedness of the population led to substantially reduced damage during the latter event. Regarding the efficiency of contemporary integrated flood risk management, it is concluded that additional policies are required in order to further increase the level of preparedness of the flood-prone population. This especially concerns households in areas that are less frequently affected by flood events.

  10. N-acetyl cysteine mitigates the acute effects of cocaine-induced toxicity in astroglia-like cells.

    Directory of Open Access Journals (Sweden)

    Ramesh B Badisa

    Full Text Available Cocaine has a short half-life of only about an hour but its effects, predominantly on the central nervous system (CNS, are fairly long-lasting. Of all cells within the CNS, astrocytes may be the first to display cocaine toxicity owing to their relative abundance in the brain. Cocaine entry could trigger several early response changes that adversely affect their survival, and inhibiting these changes could conversely increase their rate of survival. In order to identify these changes and the minimal concentrations of cocaine that can elicit them in vitro, rat C6 astroglia-like cells were treated with cocaine (2-4 mM for 1h and assayed for alterations in gross cell morphology, cytoplasmic vacuolation, viability, reactive oxygen species (ROS generation, glutathione (GSH levels, cell membrane integrity, F-actin cytoskeleton, and histone methylation. We report here that all of the above identified features are significantly altered by cocaine, and may collectively represent the key pathology underlying acute toxicity-mediated death of astroglia-like cells. Pretreatment of the cells with the clinically available antioxidant N-acetyl cysteine (NAC, 5 mM for 30 min inhibited these changes during subsequent application of cocaine and mitigated cocaine-induced toxicity. Despite repeated cocaine exposure, NAC pretreated cells remained highly viable and post NAC treatment also increased viability of cocaine treated cells to a smaller yet significant level. We show further that this alleviation by NAC is mediated through an increase in GSH levels in the cells. These findings, coupled with the fact that astrocytes maintain neuronal integrity, suggest that compounds which target and mitigate these early toxic changes in astrocytes could have a potentially broad therapeutic role in cocaine-induced CNS damage.

  11. Interactive effects of nitric oxide and glutathione in mitigating copper toxicity of rice (Oryza sativa L.) seedlings. (United States)

    Mostofa, Mohammad Golam; Seraj, Zeba Islam; Fujita, Masayuki


    Nitric oxide (NO) and glutathione (GSH) are 2 vital components of the antioxidant system that play diverse roles in plant responses to abiotic stresses. Recently, we have reported that exogenous supply of both these molecules reduced copper (Cu) toxicity in rice seedlings. Individual as well as co-treatment of sodium nitroprusside (SNP: a NO donor) and GSH with Cu significantly mitigated the adverse effects of Cu, evident in the reduced level of oxidative markers such as H2O2, superoxide (O2(·-)), malondialdehyde (MDA), and proline (Pro). GSH content and most of the antioxidative and glyoxalase enzymes were up-regulated upon Cu stress, indicating their responses were co-related with the level of stress. Our results indicated that direct ROS scavenging, reduced Cu uptake, and the balanced antioxidative and glyoxalase systems, at least in part, successfully executed NO- and GSH-mediated alleviation of Cu toxicity in rice seedlings. In addition, the combined effect of adding SNP and GSH together was more efficient than the effect of adding them individually. Here, we are speculating that 1) GSH and Pro could be used as potential markers for copper stress, and 2) adding SNP and GSH might produce S-nitrosoglutathione (GSNO) which could be a source of bioactive NO and may affect many regulatory processes involved in Cu-stress tolerance. We further note that the combined effect of adding SNP and GSH was pronounced in inhibiting the uptake and translocation of Cu in rice seedlings.

  12. The latex sap of the 'Old World Plant' Lagenaria siceraria with potent lectin activity mitigates neoplastic malignancy targeting neovasculature and cell death. (United States)

    Vigneshwaran, V; Thirusangu, Prabhu; Madhusudana, S; Krishna, V; Pramod, Siddanakoppalu N; Prabhakar, B T


    Lifestyle and dietary modifications have contributed much to somatic genetic alteration which has concomitantly led to increase in malignant diseases. Henceforth, plant based and dietary interventions to mitigate and impede oncogenic transformation are in great demand. We investigated the latex sap (LSL) of the dietary Lagenaria siceraria vegetable, the first domesticated plant species with the potent lectin activity for its functional role against the tumor progression and its mechanism. LSL has markedly stimulated proliferation of lymphocytes and displayed strong cytotoxic activity against cancer both in-vitro and in-vivo. The tumor regression was paralleled with drastic reduction in tumoral neovasculature as evidenced from angiogenic parameters and abrogated related gene expressions. LSL has also triggered apoptotic signaling cascade in cancer cells through activation of caspase-3 mediated activation of endonuclease and inducing apoptotic cellular events. Collectively our study provides tangible evidences that latex sap from L. siceraria with immunopotentiating ability significantly regresses the tumor progression by targeting angiogenesis and inducing cell death.

  13. Monitoring and Mitigation Alternatives for Protection of North Atlantic Right Whales during Offshore Wind Farm Installation

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, Thomas J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Halvorsen, Michele B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Matzner, Shari [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Copping, Andrea E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Stavole, Jessica [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)


    Progress report on defining and determining monitoring and mitigation measures for protecting North Atlantic Right Whales from the effects of pile driving and other activities associated with installation of offshore wind farms.

  14. Assessment of stone columns as a mitigation technique of liquefaction-induced effects during Italian earthquakes (May 2012). (United States)

    Forcellini, Davide; Tarantino, Angelo Marcello


    Soil liquefaction has been observed worldwide during recent major earthquakes with induced effects responsible for much of the damage, disruption of function, and considerable replacement expenses for structures. The phenomenon has not been documented in recent time with such damage in Italian context before the recent Emilia-Romagna Earthquake (May 2012). The main lateral spreading and vertical deformations affected the stability of many buildings and impacted social life inducing valuable lessons on liquefaction risk assessment and remediation. This paper aims first of all to reproduce soil response to liquefaction-induced lateral effects and thus to evaluate stone column mitigation technique effectiveness by gradually increasing the extension of remediation, in order to achieve a satisfactory lower level of permanent deformations. The study is based on the use of a FE computational interface able to analyse the earthquake-induced three-dimensional pore pressure generation adopting one of the most credited nonlinear theories in order to assess realistically the displacements connected to lateral spreading.

  15. Mitigation of Effects of Occlusion on Object Recognition with Deep Neural Networks through Low-Level Image Completion. (United States)

    Chandler, Benjamin; Mingolla, Ennio


    Heavily occluded objects are more difficult for classification algorithms to identify correctly than unoccluded objects. This effect is rare and thus hard to measure with datasets like ImageNet and PASCAL VOC, however, owing to biases in human-generated image pose selection. We introduce a dataset that emphasizes occlusion and additions to a standard convolutional neural network aimed at increasing invariance to occlusion. An unmodified convolutional neural network trained and tested on the new dataset rapidly degrades to chance-level accuracy as occlusion increases. Training with occluded data slows this decline but still yields poor performance with high occlusion. Integrating novel preprocessing stages to segment the input and inpaint occlusions is an effective mitigation. A convolutional network so modified is nearly as effective with more than 81% of pixels occluded as it is with no occlusion. Such a network is also more accurate on unoccluded images than an otherwise identical network that has been trained with only unoccluded images. These results depend on successful segmentation. The occlusions in our dataset are deliberately easy to segment from the figure and background. Achieving similar results on a more challenging dataset would require finding a method to split figure, background, and occluding pixels in the input.

  16. Mitigation of Effects of Occlusion on Object Recognition with Deep Neural Networks through Low-Level Image Completion

    Directory of Open Access Journals (Sweden)

    Benjamin Chandler


    Full Text Available Heavily occluded objects are more difficult for classification algorithms to identify correctly than unoccluded objects. This effect is rare and thus hard to measure with datasets like ImageNet and PASCAL VOC, however, owing to biases in human-generated image pose selection. We introduce a dataset that emphasizes occlusion and additions to a standard convolutional neural network aimed at increasing invariance to occlusion. An unmodified convolutional neural network trained and tested on the new dataset rapidly degrades to chance-level accuracy as occlusion increases. Training with occluded data slows this decline but still yields poor performance with high occlusion. Integrating novel preprocessing stages to segment the input and inpaint occlusions is an effective mitigation. A convolutional network so modified is nearly as effective with more than 81% of pixels occluded as it is with no occlusion. Such a network is also more accurate on unoccluded images than an otherwise identical network that has been trained with only unoccluded images. These results depend on successful segmentation. The occlusions in our dataset are deliberately easy to segment from the figure and background. Achieving similar results on a more challenging dataset would require finding a method to split figure, background, and occluding pixels in the input.

  17. A new cost-effective method to mitigate ammonia loss from intensive cattle feedlots: application of lignite (United States)

    Chen, Deli; Sun, Jianlei; Bai, Mei; Dassanayake, Kithsiri B.; Denmead, Owen T.; Hill, Julian


    In open beef feedlot systems, more than 50% of dietary nitrogen (N) is lost as ammonia (NH3). Here we report an effective and economically-viable method to mitigate NH3 emissions by the application of lignite. We constructed two cattle pens (20 × 20 m) to determine the effectiveness of lignite in reducing NH3 emissions. Twenty-four steers were fed identical commercial rations in each pen. The treatment pen surface was dressed with 4.5 kg m-2 lignite dry mass while no lignite was applied in the control pen. We measured volatilised NH3 concentrations using Ecotech EC9842 NH3 analysers in conjunction with a mass balance method to calculate NH3 fluxes. Application of lignite decreased NH3 loss from the pen by approximately 66%. The cumulative NH3 losses were 6.26 and 2.13 kg N head-1 in the control and lignite treatment, respectively. In addition to the environmental benefits of reduced NH3 losses, the value of retained N nutrient in the lignite treated manure is more than $37 AUD head-1 yr-1, based on the current fertiliser cost and estimated cost of lignite application. We show that lignite application is a cost-effective method to reduce NH3 loss from cattle feedlots.

  18. Better executive function under stress mitigates the effects of recent life stress exposure on health in young adults. (United States)

    Shields, Grant S; Moons, Wesley G; Slavich, George M


    Executive function is a neuropsychological construct that enables controlled cognitive processing, which has been hypothesized to enhance individuals' resilience to stress. However, little empirical work has directly examined how executive function under different conditions mitigates the negative effects of stress exposure on health. To address this issue, we recruited 110 healthy young adults and assessed their recent life stress exposure, executive function in either a stressful or non-stressful context, and current health complaints. Based on existing research, we hypothesized that individuals exhibiting better executive function following a laboratory-based stressor (but not a control task) would demonstrate weaker associations between recent stress exposure and health because they perceived recent life stressors as being less severe. Consistent with this hypothesis, better executive function during acute stress, but not in the absence of stress, was associated with an attenuated link between participants' recent life stress exposure and their current health complaints. Moreover, this attenuating effect was mediated by lesser perceptions of stressor severity. Based on these data, we conclude that better executive function under stress is associated with fewer health complaints and that these effects may occur by reducing individuals' perceptions of stressor severity. The data thus suggest the possibility of reducing stress-related health problems by enhancing executive function.

  19. Climate Change Impacts and Greenhouse Gas Mitigation Effects on U.S. Hydropower Generation (United States)

    Climate change will have potentially significant effects on hydropower generation due to changes in the magnitude and seasonality of river runoff and increases in reservoir evaporation. These physical impacts will in turn have economic consequences through both producer revenues ...

  20. Tolazoline reversal of xylazine in bison (Bison bison): Mitigation of adverse effects (United States)

    Roffe, Thomas J.; Sweeney, Steven J.; Williams, Beth; Quist, Charlotte


    Tolazoline is a mixed alpha-1 and -2 adrenergic antagonist used to reverse the sedative, analgesic and muscle-relaxing effects of xylazine, a potent alpha adrenergic agonist. Tolazoline has been used in cattle and is superior to yohimbine, another alpha adrenergic antagonist, in this species. In white-tailed deer, tolazoline shortened recovery times and reversed xylazine-induced bradycardia, respiratory depression, and bloat following xylazine-ketamine anesthesia (Kreeger et al. 1986). We have used it for a number of years in moose without any detected adverse reactions. Caulkett et al. (2000) used tolazoline in wood bison to reverse the xylazine-induced effects of xylazine-tiletamine/zolazepam anesthesia and did not report any ill effects. However, the reported side effects of tolazoline in horses (species for which the drug was developed and is labeled) include abdominal discomfort, gastrointestinal hypermotility, diarrhea, tachycardia, ventricular dysrhythmia, hypertension and apprehensiveness.

  1. The effects of adaptation and mitigation on coastal flood impacts during the 21st century. An application of the DIVA and IMAGE models

    NARCIS (Netherlands)

    Hinkel, J.; Vuuren, D.P. van; Nicholls, R.J.; Klein, R.J.T.


    This paper studies the effects of mitigation and adaptation on coastal flood impacts. We focus on a scenario that stabilizes concentrations at 450 ppm-CO 2-eq leading to 42 cm of global mean sea-level rise in 1995-2100 (GMSLR) and an unmitigated one leading to 63 cm of GMSLR. We also consider sensit

  2. Mechanical robustness of the calcareous tubeworm Hydroides elegans: warming mitigates the adverse effects of ocean acidification. (United States)

    Li, Chaoyi; Meng, Yuan; He, Chong; Chan, Vera B S; Yao, Haimin; Thiyagarajan, V


    Development of antifouling strategies requires knowledge of how fouling organisms would respond to climate change associated environmental stressors. Here, a calcareous tube built by the tubeworm, Hydroides elegans, was used as an example to evaluate the individual and interactive effects of ocean acidification (OA), warming and reduced salinity on the mechanical properties of a tube. Tubeworms produce a mechanically weaker tube with less resistance to simulated predator attack under OA (pH 7.8). Warming (29°C) increased tube volume, tube mineral density and the tube's resistance to a simulated predatory attack. A weakening effect by OA did not make the removal of tubeworms easier except for the earliest stage, in which warming had the least effect. Reduced salinity (27 psu) did not affect tubes. This study showed that both mechanical analysis and computational modeling can be integrated with biofouling research to provide insights into how fouling communities might develop in future ocean conditions.

  3. Mitigating the effect of non-uniform loss on time reversal mirrors

    CERN Document Server

    Taddese, Biniyam Tesfaye; Ott, Edward; Anlage, Steven M


    Time reversal mirrors work perfectly only for lossless wave propagation. Here, the performance of time-reversal mirrors is quantitatively defined, and the adverse effect of dissipation on their performance is investigated. The technique of exponential amplification is proposed to overcome the effect of dissipation in the case of uniform loss distributions, and, to some extent, in the case of non-uniform loss distributions. A numerical model of a star graph was employed to test the applicability of this technique on realizations with various random spatial distributions of loss. The numerical results are also verified by an experimental result from an electromagnetic time-reversal mirror.

  4. Climate Change Impacts and Greenhouse Gas Mitigation Effects on US Water Quality (United States)

    Climate change will have potentially significant effects on freshwater quality due to increases in river and lake temperatures, changes in the magnitude and seasonality of river runoff, and more frequent and severe extreme events. These physical impacts will in turn have economic...

  5. Traffic related air pollution : spatial variation, health effects and mitigation measures

    NARCIS (Netherlands)

    Dijkema, M.B.A.


    Air pollution is probably the most intensely studied field in today’s environmental health research. The extensive body of literature on health effects associated with air pollution exposure has lead to prioritization of air pollution as public health risk factor and air quality regulations worldwid

  6. Assessing the effectiveness of vegetative environmental buffers in mitigating air pollutant emissions from poultry houses (United States)

    Over 560 million broilers are produced on the Delmarva Peninsula each year. However, emissions from poultry houses have come under intense scrutiny due to the potential human and environmental effects of the released particulate matter (PM), ammonia, and volatile organic compounds (VOCs). Ammonia an...

  7. Framework to determine the effectiveness of dietary exposure mitigation to chemical contaminants

    NARCIS (Netherlands)

    Fels, van der H.J.; Edwards, S.; Kennedy, M.; O'Hagan, A.; O'Mahony, C.; Scholz, G.; Steinberg, P.; Tennant, D.; Chiodini, A.


    In order to ensure the food safety, risk managers may implement measures to reduce human exposure to contaminants via food consumption. The evaluation of the effect of a measure is often an overlooked step in risk analysis process. The aim of this study was to develop a systematic approach for deter

  8. In vivo and in vitro effects of a blend of essential oils on rumen methane mitigation

    NARCIS (Netherlands)

    Castro-Montoya, J.; Peiren, N.; Cone, J.W.; Zweifel, B.; Fievez, V.; Campeneere, De S.


    The effect of Agolin Ruminant, a blend of essential oils, on methane (CH4) emissions were investigated in two in vivo experiments and in four in vitro experiments. In the in vivo experiments, four lactating dairy cows and four beef heifers were supplemented 0.2 g/d of the essential oils (ca. 2–4 ppm

  9. Public health activities for mitigation of radiation exposures and risk communication challenges after the Fukushima nuclear accident. (United States)

    Shimura, Tsutomu; Yamaguchi, Ichiro; Terada, Hiroshi; Robert Svendsen, Erik; Kunugita, Naoki


    Herein we summarize the public health actions taken to mitigate exposure of the public to radiation after the Fukushima accident that occurred on 11 March 2011 in order to record valuable lessons learned for disaster preparedness. Evacuations from the radiation-affected areas and control of the distribution of various food products contributed to the reduction of external and internal radiation exposure resulting from the Fukushima incident. However, risk communication is also an important issue during the emergency response effort and subsequent phases of dealiing with a nuclear disaster. To assist with their healing process, sound, reliable scientific information should continue to be disseminated to the radiation-affected communities via two-way communication. We will describe the essential public health actions following a nuclear disaster for the early, intermediate and late phases that will be useful for radiological preparedness planning in response to other nuclear or radiological disasters.

  10. A regional assessment of the cost and effectiveness of mitigation measures for reducing nutrient losses to water and greenhouse gas emissions to air from pastoral farms. (United States)

    Vibart, Ronaldo; Vogeler, Iris; Dennis, Samuel; Kaye-Blake, William; Monaghan, Ross; Burggraaf, Vicki; Beautrais, Josef; Mackay, Alec


    Using a novel approach that links geospatial land resource information with individual farm-scale simulation, we conducted a regional assessment of nitrogen (N) and phosphorous (P) losses to water and greenhouse gas (GHG) emissions to air from the predominant mix of pastoral industries in Southland, New Zealand. An evaluation of the cost-effectiveness of several nutrient loss mitigation strategies applied at the farm-scale, set primarily for reducing N and P losses and grouped by capital cost and potential ease of adoption, followed an initial baseline assessment. Grouped nutrient loss mitigation strategies were applied on an additive basis on the assumption of full adoption, and were broadly identified as 'improved nutrient management' (M1), 'improved animal productivity' (M2), and 'restricted grazing' (M3). Estimated annual nitrate-N leaching losses occurring under representative baseline sheep and beef (cattle) farms, and representative baseline dairy farms for the region were 10 ± 2 and 32 ± 6 kg N/ha (mean ± standard deviation), respectively. Both sheep and beef and dairy farms were responsive to N leaching loss mitigation strategies in M1, at a low cost per kg N-loss mitigated. Only dairy farms were responsive to N leaching loss abatement from adopting M2, at no additional cost per kg N-loss mitigated. Dairy farms were also responsive to N leaching loss abatement from adopting M3, but this reduction came at a greater cost per kg N-loss mitigated. Only dairy farms were responsive to P-loss mitigation strategies, in particular by adopting M1. Only dairy farms were responsive to GHG abatement; greater abatement was achieved by the most intensified dairy farm system simulated. Overall, M1 provided for high levels of regional scale N- and P-loss abatement at a low cost per farm without affecting overall farm production, M2 provided additional N-loss abatement but only marginal P-loss abatement, whereas M3 provided the greatest N-loss abatement, but

  11. Single event effects on digital integrated circuits: origins and mitigation techniques


    Velazco, Raoul; Franco Peláez, Francisco Javier


    New generation electronic devices have become more and more sensitive to the effects of the natural radiation coming from the surrounding environment. These radiation sources are cosmic rays and radioactive impurities, able to corrupt the content of memory cells or to induce transient pulses in combinational logic. The growing sensitivity seems to be related to two main factors: the lower and lower charge needed to define the logic levels in advanced devices and the increasing number of basic...

  12. Effect of industrial by-products containing electron acceptors on mitigating methane emission during rice cultivation. (United States)

    Ali, Muhammad Aslam; Lee, Chang Hoon; Kim, Sang Yoon; Kim, Pil Joo


    Three industrial by-products (fly ash, phosphogypsum and blast furnace slag), were evaluated for their potential re-use as soil amendments to reduce methane (CH(4)) emission resulting from rice cultivation. In laboratory incubations, CH(4) production rates from anoxic soil slurries were significantly reduced at amendment levels of 0.5%, 1%, 2% and 5% (wt wt(-1)), while observed CO(2) production rates were enhanced. The level of suppression in methane production was the highest for phosphogypsum, followed by blast slag and then fly ash. In the greenhouse experiment, CH(4) emission rates from the rice planted potted soils significantly decreased with the increasing levels (2-20 Mg ha(-1)) of the selected amendments applied, while rice yield simultaneously increased compared to the control treatment. At 10 Mg ha(-1) application level of the amendments, total seasonal CH(4) emissions were reduced by 20%, 27% and 25%, while rice grain yields were increased by 17%, 15% and 23% over the control with fly ash, phosphogypsum, and blast slag amendments, respectively. The suppression of CH(4) production rates as well as total seasonal CH(4) flux could be due to the increased concentrations of active iron, free iron, manganese oxides, and sulfate in the amended soil, which acted as electron acceptors and controlled methanogens' activity by limiting substrates availability. Among the amendments, blast furnace slag and fly ash contributed mainly to improve the soil nutrients balance and increased the soil pH level towards neutral point, but soil acidity was developed with phosphogypsum application. Conclusively, blast slag among the selected amendments would be a suitable soil amendment for reducing CH(4) emissions as well as sustaining rice productivity.

  13. Mitigating effects of hUCB-MSCs on the hematopoietic syndrome resulting from total body irradiation. (United States)

    Shim, Sehwan; Lee, Seung Bum; Lee, Jong-geol; Jang, Won-Suk; Lee, Sun-Joo; Park, Sunhoo; Lee, Seung-Sook


    This study evaluated the clinical and pathologic effects of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in the recovery from total body irradiation by comparing it with the effects of granulocyte-colony stimulating factor (G-CSF), an efficacious drug in the treatment of acute bone marrow radiation syndrome. BALB/c mice were treated with G-CSF or hUCB-MSCs after they were irradiated with 7 Gy cobalt-60 γ-rays. Circulating blood counts, histopathologic changes in the bone marrow, and plasma level of Flt-3L and transforming growth factor (TGF-β1) were monitored in the postirradiation period. Hematologic analysis revealed that the peripheral leukocyte counts were markedly increased in the hUCB-MSCs-treated group, whereas G-CSF-treated mice did not recover significantly. Moreover, differential counts showed that hUCB-MSC treatment has regenerative effects on white blood cells, lymphocytes, and monocytes compared with the irradiated group. Treatment with hUCB-MSCs or G-CSF significantly increased immunoreactivity of Ki-67 until 3 weeks after total body irradiation. However, at 3 weeks, the number of Ki-67 immunoreactive cells significantly increased in the hUCB-MSCs-treated group compared with the G-CSF-treated group. Furthermore, hUCB-MSC treatment significantly modulated plasma levels of the hematopoietic cytokines Flt-3L and TGF-β1, whereas G-CSF treatment failed to decrease the plasma Flt-3L levels at 2 weeks after irradiation. Based on the differences in circulating blood cell reconstitution and cell density of bone marrow, the authors suggest that MSC treatment is superior to G-CSF treatment for hematopoietic reconstitution following sublethal dose radiation exposure.

  14. Mitigation of timing offset effect in IM/DD based OFDMA-PON uplink multiple access. (United States)

    Jung, Sun-Young; Jung, Sang-Min; Park, Hyoung-Joon; Han, Sang-Kook


    In orthogonal frequency division multiple access based passive optical network (OFDMA-PON) uplink, synchronization between optical network units (ONUs) is very important to maintain orthogonality. The synchronization among uplink signals is considered as one of the main challenges in OFDMA-PON due to optical path difference. In this paper, the performance degradation according to timing offset between ONUs is experimentally analyzed. And we propose and demonstrate timing offset effect reduction in asynchronous multiple access by using CP extension and filter bank based multicarrier (FBMC) system in intensity modulation/direct detection (IM/DD) based OFDMA-PON uplink transmission.

  15. Mitigating the Effects of Salinity by Foliar Application of Salicylic Acid in Fenugreek


    Sumaira Babar; Ejaz Hussain Siddiqi; Iqbal Hussain; Khizar Hayat Bhatti; Rizwan Rasheed


    Present research work was conducted to alleviate the salinity-induced harmful effect on biomass production and physiochemical attributes of fenugreek by foliar application of salicylic acid. Two varieties (Deli Kabul and Kasuri) were grown in salt treated (100 mM NaCl) and untreated (0 mM NaCl) growth medium. Two levels of salicylic acid (0 mg L−1 and 100 mg L−1) were applied through foliar method. Salinity stress significantly reduced the growth biomass in both varieties. Higher shoot fresh ...

  16. Mitigation of hepatotoxic effects of arsenic trioxide through omega-3 fatty acid in rats. (United States)

    Mathews, Varghese V; Paul, Mv Sauganth; Abhilash, M; Manju, Alex; Abhilash, S; Nair, R Harikumaran


    Arsenic trioxide (As(2)O(3)) is an effective drug in the treatment of leukaemia and many solid tumours. In clinical trials, arsenic therapy is closely associated with hepatic toxicity. The present study was designed to investigate the efficacy of omega-3 fatty acid against As(2)O(3)-induced hepatotoxicity. A 4 mg/kg body weight (bw) of As(2)O(3) was orally administered to Wistar male rats for 45 days. Hepatotoxicity was evaluated by biochemical tests, antioxidant assays and histopathological examinations. Arsenic accumulation was found in the liver tissue of rats treated with As(2)O(3). Hepatoprotective efficacy of omega-3 fatty acid was analysed by the combination therapy with As(2)O(3). In vivo studies revealed a significant rise in lipid peroxidation with concomitant decline in reduced glutathione, glutathione-dependant antioxidant enzymes and antiperoxidative enzymes in the liver tissue of rats treated with arsenic. The supplementation of omega-3 fatty acid at a dose of 50 mg/kg bw with As(2)O(3) offers ameliorative effect against hepatocellular toxicity. Omega-3 fatty acid maintained hepatic marker enzymes, antioxidant enzymes and decreased lipid peroxidation. The combination treatment clearly reduced the hepatic structural abnormalities such as haemorrhage, necrosis and cholangiofibrosis in the rats treated with arsenic. This study concludes that the omega-3 fatty acid might be useful for the protection against As(2)O(3)-induced hepatotoxicity.

  17. Mitigation Effect of Proanthocyanidin on Secondary Heart Injury in Rats Caused by Mechanical Trauma (United States)

    Ma, Shuo; Chen, Chong; Cao, Tingting; Bi, Yue; Zhou, Jicheng; Li, Xintao; Yu, Deqin; Li, Shuzhuang


    Multiple organ dysfunctional syndrome secondary to mechanical trauma (MT) has attracted considerable research attention. The heart is one of the most important organs of the body, and secondary cardiac insufficiency caused by MT seriously affects the quality of life. This study aims to investigate whether proanthocyanidin can alleviate myocardial injury and improve heart function in the process of MT leading to secondary cardiac insufficiency. Noble-Collip drum wasused to prepare MT model in rats. And myocardial apoptosis index was calculated after TUNEL staining. Ventricular intubation was employed to detect heart function. Changes in myocardial ultrastructure were observed using an electron microscope. ELISA was used to detect the content of TNF-α and reactive oxygen species generated from monocytes and cardiomyocytes. The changes in Ca2+ concentration in cardiomyocyte were observed by confocal microscope. Compared with trauma group, the administration group had a decreased apoptosis index of cardiomyocytes, and increased ±dp/dtmax. Meanwhile, proanthocyanidin can inhibit monocytes’ TNF-α production, and reduce plasma TNF-α concentration. Moreover, proanthocyanidin can attenuate the excessive oxidative stress reaction of cardiomyocyte, and inhibit calcium overload in cardiomyocytes. In conclusion, proanthocyanidin can effectively ease myocardial damage and improve cardiac function, through anti-inflammatory and antioxidant effects in secondary cardiac insufficiency caused by MT. PMID:28294148

  18. Photoprotection by foliar anthocyanins mitigates effects of boron toxicity in sweet basil (Ocimum basilicum). (United States)

    Landi, Marco; Guidi, Lucia; Pardossi, Alberto; Tattini, Massimiliano; Gould, Kevin S


    Boron (B) toxicity is an important agricultural problem in arid environments. Excess edaphic B compromises photosynthetic efficiency, limits growth and reduces crop yield. However, some purple-leafed cultivars of sweet basil (Ocimum basilicum) exhibit greater tolerance to high B concentrations than do green-leafed cultivars. We hypothesised that foliar anthocyanins protect basil leaf mesophyll from photo-oxidative stress when chloroplast function is compromised by B toxicity. Purple-leafed 'Red Rubin' and green-leafed 'Tigullio' cultivars, grown with high or negligible edaphic B, were given a photoinhibitory light treatment. Possible effects of photoabatement by anthocyanins were simulated by superimposing a purple polycarbonate filter on the green leaves. An ameliorative effect of light filtering on photosynthetic quantum yield and on photo-oxidative load was observed in B-stressed plants. In addition, when green protoplasts from both cultivars were treated with B and illuminated through a screen of anthocyanic protoplasts or a polycarbonate film which approximated cyanidin-3-O-glucoside optical properties, the degree of photoinhibition, hydrogen peroxide production, and malondialdehyde content were reduced. The data provide evidence that anthocyanins exert a photoprotective role in purple-leafed basil mesophyll cells, thereby contributing to improved tolerance to high B concentrations.

  19. Mitigating the Effects of Family Poverty on Early Child Development through Parenting Interventions in Primary Care. (United States)

    Cates, Carolyn Brockmeyer; Weisleder, Adriana; Mendelsohn, Alan L


    Poverty related disparities in early child development and school readiness are a major public health crisis, the prevention of which has emerged in recent years as a national priority. Interventions targeting parenting and the quality of the early home language environment are at the forefront of efforts to address these disparities. In this article we discuss the innovative use of the pediatric primary care platform as part of a comprehensive public health strategy to prevent adverse child development outcomes through the promotion of parenting. Models of interventions in the pediatric primary care setting are discussed with evidence of effectiveness reviewed. Taken together, a review of this significant body of work shows the tremendous potential to deliver evidence-based preventive interventions to families at risk for poverty related disparities in child development and school readiness at the time of pediatric primary care visits. We also addresss considerations related to scaling and maximizing the effect of pediatric primary care parenting interventions and provide key policy recommendations.

  20. Nano-silicon dioxide mitigates the adverse effects of salt stress on Cucurbita pepo L. (United States)

    Siddiqui, Manzer H; Al-Whaibi, Mohamed H; Faisal, Mohammad; Al Sahli, Abdulaziz A


    Research into nanotechnology, an emerging science, has advanced in almost all fields of technology. The aim of the present study was to evaluate the role of nano-silicon dioxide (nano-SiO2 ) in plant resistance to salt stress through improvement of the antioxidant system of squash (Cucurbita pepo L. cv. white bush marrow). Seeds treated with NaCl showed reduced germination percentage, vigor, length, and fresh and dry weights of the roots and shoots. However, nano-SiO2 improved seed germination and growth characteristics by reducing malondialdehyde and hydrogen peroxide levels as well as electrolyte leakage. In addition, application of nano-SiO2 reduced chlorophyll degradation and enhanced the net photosynthetic rate (Pn ), stomatal conductance (gs ), transpiration rate, and water use efficiency. The increase in plant germination and growth characteristics through application of nano-SiO2 might reflect a reduction in oxidative damage as a result of the expression of antioxidant enzymes, such as catalase, peroxidase, superoxide dismutase, glutathione reductase, and ascorbate peroxidase. These results indicate that nano-SiO2 may improve defense mechanisms of plants against salt stress toxicity by augmenting the Pn , gs , transpiration rate, water use efficiency, total chlorophyll, proline, and carbonic anhydrase activity in the leaves of plants.

  1. Formation dry-out from CO2 injection into saline aquifers: Part 1, Effects of solids precipitation and their mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Pruess, Karsten; Muller, Nadja


    Injection of CO{sub 2} into saline aquifers may cause formation dry-out and precipitation of salt near the injection well, which may reduce formation porosity, permeability, and injectivity. This paper uses numerical simulation to explore the role of different processes and parameters in the salt precipitation process and to examine injection strategies that could mitigate the effects. The main physical mechanisms affecting the dry-out and salt precipitation process include (1) displacement of brine away from the injection well by injected CO{sub 2}, (2) dissolution (evaporation) of brine into the flowing CO{sub 2} stream, (3) upflow of CO{sub 2} due to gravity effects (buoyancy), (4) backflow of brine toward the injection point due to capillary pressure gradients that oppose the pressure gradient in the CO{sub 2}-rich ('gas') phase, and (5) molecular diffusion of dissolved salt. The different mechanisms operate on a range of spatial scales. CO{sub 2} injection at constant rate into a homogeneous reservoir with uniform initial conditions is simulated in 1-D radial geometry, to resolve multiscale processes by taking advantage of the similarity property, i.e., the evolution of system conditions as a function of radial distance R and time t depends only on the similarity variable R{sup 2}/t. Simulations in 2-D vertical cross sections are used to examine the role of gravity effects. We find that counterflow of CO{sub 2} and brine can greatly increase aqueous phase salinity and can promote substantial salt precipitation even in formations with low dissolved solids. Salt precipitation can accentuate effects of gravity override. We find that injecting a slug of fresh water prior to commencement of CO{sub 2} injection can reduce salt precipitation and permeability loss near the injection well.

  2. Isolating social influences on vulnerability to earthquake shaking: identifying cost-effective mitigation strategies. (United States)

    Bhloscaidh, Mairead Nic; McCloskey, John; Pelling, Mark; Naylor, Mark


    Until expensive engineering solutions become more universally available, the objective targeting of resources at demonstrably effective, low-cost interventions might help reverse the trend of increasing mortality in earthquakes. Death tolls in earthquakes are the result of complex interactions between physical effects, such as the exposure of the population to strong shaking, and the resilience of the exposed population along with supporting critical infrastructures and institutions. The identification of socio-economic factors that contribute to earthquake mortality is crucial to identifying and developing successful risk management strategies. Here we develop a quantitative methodology more objectively to assess the ability of communities to withstand earthquake shaking, focusing on, in particular, those cases where risk management performance appears to exceed or fall below expectations based on economic status. Using only published estimates of the shaking intensity and population exposure for each earthquake, data that is available for earthquakes in countries irrespective of their level of economic development, we develop a model for mortality based on the contribution of population exposure to shaking only. This represents an attempt to remove, as far as possible, the physical causes of mortality from our analysis (where we consider earthquake engineering to reduce building collapse among the socio-economic influences). The systematic part of the variance with respect to this model can therefore be expected to be dominated by socio-economic factors. We find, as expected, that this purely physical analysis partitions countries in terms of basic socio-economic measures, for example GDP, focusing analytical attention on the power of economic measures to explain variance in observed distributions of earthquake risk. The model allows the definition of a vulnerability index which, although broadly it demonstrates the expected income-dependence of vulnerability to

  3. The Effects of the Tractor and Semitrailer Routing Problem on Mitigation of Carbon Dioxide Emissions

    Directory of Open Access Journals (Sweden)

    Hongqi Li


    Full Text Available The incorporation of CO2 emissions minimization in the vehicle routing problem (VRP is of critical importance to enterprise practice. Focusing on the tractor and semitrailer routing problem with full truckloads between any two terminals of the network, this paper proposes a mathematical programming model with the objective of minimizing CO2 emissions per ton-kilometer. A simulated annealing (SA algorithm is given to solve practical-scale problems. To evaluate the performance of the proposed algorithm, a lower bound is developed. Computational experiments on various problems generated randomly and a realistic instance are conducted. The results show that the proposed methods are effective and the algorithm can provide reasonable solutions within an acceptable computational time.

  4. Protracted effects of juvenile stressor exposure are mitigated by access to palatable food.

    Directory of Open Access Journals (Sweden)

    Jennifer Christine MacKay

    Full Text Available Stressor experiences during the juvenile period may increase vulnerability to anxiety and depressive-like symptoms in adulthood. Stressors may also promote palatable feeding, possibly reflecting a form of self-medication. The current study investigated the short- and long-term consequences of a stressor applied during the juvenile period on anxiety- and depressive-like behavior measured by the elevated plus maze (EPM, social interaction and forced swim test (FST. Furthermore, the effects of stress on caloric intake, preference for a palatable food and indices of metabolic syndrome and obesity were assessed. Male Wistar rats exposed to 3 consecutive days of variable stressors on postnatal days (PD 27-29, displayed elevated anxiety-like behaviors as adults, which could be attenuated by consumption of a palatable high-fat diet. However, consumption of a palatable food in response to a stressor appeared to contribute to increased adiposity.

  5. Mitigation of Memory Effects in Beta Scintillation Cells for Radioactive Gas Detection

    Energy Technology Data Exchange (ETDEWEB)

    Seifert, Carolyn E; McIntyre, Justin I; Antolick, Kathryn C; Carman, April J; Cooper, Matthew W; Hayes, James C; Heimbigner, Tom R; Hubbard, C W; Litke, Kevin E; Ripplinger, Mike D; Suarez, Reynold


    The Automated Radioxenon Sampler/Analyzer (ARSA) developed at PNNL measures the relative concentrations of xenon isotopes using a coincidence system. Previous tests of the ARSA system have shown that latent radioactivity remains in the plastic cells after evacuation of the gases, leading to a “memory effect” in which the background count rate is dependent on the sample history. The increased background results in lower detection sensitivity. Two possible solutions to the memory effect are explored in this work: depositing a thin layer of metal on the plastic cell (“metallization”), and using an inorganic scintillating cell composed of yttrium aluminum perovskite (YAP). In both cases, the presence of inorganic material at the surface is intended to inhibit the diffusion of gases into the cell walls.

  6. Employee Communicative Actions and Companies' Communication Strategies to Mitigate the Negative Effects of Crises

    DEFF Research Database (Denmark)

    Mazzei, Alessandra; Ravazzani, Silvia


    Abstract: Can communication with employees lessen the negative effects of a crisis? In the pre-crisis stage, employee communication can strengthen internal commitment, while in the crisis stage it can reinforce the commitment by means of accommodative crisis communication strategies. Employee...... commitment is at the basis of positive employee communicative actions, like advocacy and positive referrals, which finally protect the company’s reputation. After a theoretical exploration of these issues, this chapter presents first a case study showing how continuous internal communication efforts...... and factual communication based on managers’ and company’s actions are crucial in order to build quality relationships with employees. In turn, this leads to positive employee communicative actions when a crisis occurs. Second, it illustrates a survey of Italian companies which examined internal crisis...

  7. Opioid-induced hyperalgesia in chronic pain patients and the mitigating effects of gabapentin. (United States)

    Stoicea, Nicoleta; Russell, Daric; Weidner, Greg; Durda, Michael; Joseph, Nicholas C; Yu, Jeffrey; Bergese, Sergio D


    Chronic pain patients receiving opioid drugs are at risk for opioid-induced hyperalgesia (OIH), wherein opioid pain medication leads to a paradoxical pain state. OIH involves central sensitization of primary and secondary afferent neurons in the dorsal horn and dorsal root ganglion, similar to neuropathic pain. Gabapentin, a gamma-aminobutyric acid (GABA) analog anticonvulsant used to treat neuropathic pain, has been shown in animal models to reduce fentanyl hyperalgesia without compromising analgesic effect. Chronic pain patients have also exhibited lower opioid consumption and improved pain response when given gabapentin. However, few human studies investigating gabapentin use in OIH have been performed in recent years. In this review, we discuss the potential mechanisms that underlie OIH and provide a critical overview of interventional therapeutic strategies, especially the clinically-successful drug gabapentin, which may reduce OIH.

  8. Opioid-Induced Hyperalgesia in Chronic Pain Patients and the Mitigating Effects of Gabapentin

    Directory of Open Access Journals (Sweden)

    Nicoleta eStoicea


    Full Text Available Chronic pain patients receiving opioid drugs are at risk for opioid-induced hyperalgesia (OIH, wherein opioid pain medication leads to a paradoxical pain state. OIH involves central sensitization of primary and secondary afferent neurons in the dorsal horn and dorsal root ganglion, similar to neuropathic pain. Gabapentin, a gamma-aminobutyric acid (GABA analogue anticonvulsant used to treat neuropathic pain, has been shown in animal models to reduce fentanyl hyperalgesia without compromising analgesic effect. Chronic pain patients have also exhibited lower opioid consumption and improved pain response when given gabapentin. However, few human studies investigating gabapentin use in OIH have been performed in recent years. In this review, we discuss the potential mechanisms that underlie OIH and provide a critical overview of interventional therapeutic strategies, especially the clinically-successful drug gabapentin, which may reduce OIH.

  9. Automatic Identification of Critical Data Items in a Database to Mitigate the Effects of Malicious Insiders (United States)

    White, Jonathan; Panda, Brajendra

    A major concern for computer system security is the threat from malicious insiders who target and abuse critical data items in the system. In this paper, we propose a solution to enable automatic identification of critical data items in a database by way of data dependency relationships. This identification of critical data items is necessary because insider threats often target mission critical data in order to accomplish malicious tasks. Unfortunately, currently available systems fail to address this problem in a comprehensive manner. It is more difficult for non-experts to identify these critical data items because of their lack of familiarity and due to the fact that data systems are constantly changing. By identifying the critical data items automatically, security engineers will be better prepared to protect what is critical to the mission of the organization and also have the ability to focus their security efforts on these critical data items. We have developed an algorithm that scans the database logs and forms a directed graph showing which items influence a large number of other items and at what frequency this influence occurs. This graph is traversed to reveal the data items which have a large influence throughout the database system by using a novel metric based formula. These items are critical to the system because if they are maliciously altered or stolen, the malicious alterations will spread throughout the system, delaying recovery and causing a much more malignant effect. As these items have significant influence, they are deemed to be critical and worthy of extra security measures. Our proposal is not intended to replace existing intrusion detection systems, but rather is intended to complement current and future technologies. Our proposal has never been performed before, and our experimental results have shown that it is very effective in revealing critical data items automatically.

  10. Riparian forest buffers mitigate the effects of deforestation on fish assemblages in tropical headwater streams. (United States)

    Lorion, Christopher M; Kennedy, Brian P


    Riparian forest buffers may play a critical role in moderating the impacts of deforestation on tropical stream ecosystems, but very few studies have examined the ecological effects of riparian buffers in the tropics. To test the hypothesis that riparian forest buffers can reduce the impacts of deforestation on tropical stream biota, we sampled fish assemblages in lowland headwater streams in southeastern Costa Rica representing three different treatments: (1) forested reference stream reaches, (2) stream reaches adjacent to pasture with a riparian forest buffer averaging at least 15 m in width on each bank, and (3) stream reaches adjacent to pasture without a riparian forest buffer. Land cover upstream from the study reaches was dominated by forest at all of the sites, allowing us to isolate the reach-scale effects of the three study treatments. Fish density was significantly higher in pasture reaches than in forest and forest buffer reaches, mostly due to an increase in herbivore-detritivores, but fish biomass did not differ among reach types. Fish species richness was also higher in pasture reaches than in forested reference reaches, while forest buffer reaches were intermediate. Overall, the taxonomic and trophic structure of fish assemblages in forest and forest buffer reaches was very similar, while assemblages in pasture reaches were quite distinct. These patterns were persistent across three sampling periods during our 15-month study. Differences in stream ecosystem conditions between pasture reaches and forested sites, including higher stream temperatures, reduced fruit and seed inputs, and a trend toward increased periphyton abundance, appeared to favor fish species normally found in larger streams and facilitate a native invasion process. Forest buffer reaches, in contrast, had stream temperatures and allochthonous inputs more similar to forested streams. Our results illustrate the importance of riparian areas to stream ecosystem integrity in the tropics

  11. Development of an Effective Transport Media for Juvenile Spring Chinook Salmon to Mitigate Stress and Improve Smolt Survival During Columbia River Fish Hauling Operations, 1985 Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Wedemeyer, Gary A.


    Selected transport media consisting of mineral salt additions (Na/sup +/, Cl/sup -/, Ca/sup + +/, PO/sub 4//sup -3/, HCO/sub 3//sup -/, and Mg/sup + +/), mineral salts plus tranquilizing concentrations of tricaine methane sulfonate (MS-222), or MS-222 alone were tested for their ability to mitigate stress and increase smolt survival during single and mixed species hauling of Columbia River spring chinook salmon (Oncorhynchus tshawytscha) and steelhead trout (Salmo gairdneri). Successful stress mitigation was afforded by several formulations as indicated by protection against life-threatening osmoregulatory and other physiological dysfunctions, and against immediate and delayed hauling mortality. Effects on the seawater survival and growth of smolts hauled in transport media were used as the overall criterion of success. Of the fourteen chemical formulations tested, 10 ppM MS-222 emerged as top-rated in terms of ability to mitigate physiological stress during single and mixed species transport of juvenile spring chinook salmon at hauling densities of 0.5 or 1.0 lb/gallon. Immediate and delayed mortalities from hauling stress were also reduced, but benefits to early marine growth and survival were limited to about the first month in seawater. The two physical factors tested (reduced light intensity and water temperature) were generally less effective than mineral salt additions in mitigating hauling stress, but the degree of protection afforded by reduced light intensity was nevertheless judged to be physiologically beneficial. 36 refs., 1 fig., 19 tabs.

  12. Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic Arabidopsis thaliana. (United States)

    Yuan, Xiaowei; Li, Yaxiao; Liu, Shiyang; Xia, Fei; Li, Xinzheng; Qi, Baoxiu


    IgASE1, a C₁₈ Δ(9)-specific polyunsaturated fatty acid elongase from the marine microalga Isochrysis galbana, is able to convert linoleic acid and α-linolenic acid to eicosadienoic acid and eicosatrienoic acid in Arabidopsis. Eicosadienoic acid and eicosatrienoic acid are precursors of arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid, which are synthesized via the Δ(8) desaturation biosynthetic pathways. This study shows that the IgASE1-expressing transgenic Arabidopsis exhibited altered morphology (decreased leaf area and biomass) and enhanced drought resistance compared to wild-type plants. The transgenic Arabidopsis were hypersensitive to abscisic acid (ABA) during seed germination, post-germination growth, and seedling development. They had elevated leaf ABA levels under well-watered and dehydrated conditions and their stomata were more sensitive to ABA. Exogenous application of eicosadienoic acid and eicosatrienoic acid can mimic ABA and drought responses in the wild type plants, similar to that found in the transgenic ones. The transcript levels of genes involved in the biosynthesis of ABA (NCED3, ABA1, AAO3) as well as other stress-related genes were upregulated in this transgenic line upon osmotic stress (300 mM mannitol). Taken together, these results indicate that these two eicosapolyenoic acids or their derived metabolites can mitigate the effects of drought in transgenic Arabidopsis, at least in part, through the action of ABA.

  13. Enterobacter asburiae KE17 association regulates physiological changes and mitigates the toxic effects of heavy metals in soybean. (United States)

    Kang, S-M; Radhakrishnan, R; You, Y-H; Khan, A-L; Lee, K-E; Lee, J-D; Lee, I-J


    This study aimed to elucidate the role played by Enterobacter asburiae KE17 in the growth and metabolism of soybeans during copper (100 μm Cu) and zinc (100 μm Zn) toxicity. When compared to controls, plants grown under Cu and Zn stress exhibited significantly lower growth rates, but inoculation with E. asburiae KE17 increased growth rates of stressed plants. The concentrations of plant hormones (abscisic acid and salicylic acid) and rates of lipid peroxidation were higher in plants under heavy metal stress, while total chlorophyll, carotenoid content and total polyphenol concentration were lower. While the bacterial treatment reduced the abscisic acid and salicylic acid content and lipid peroxidation rate of Cu-stressed plants, it also increased the concentration of photosynthetic pigments and total polyphenol. Moreover, the heavy metals induced increased accumulation of free amino acids such as aspartic acid, threonine, serine, glycine, alanine, leucine, isoleucine, tyrosine, proline and gamma-aminobutyric acid, while E. asburiae KE17 significantly reduced concentrations of free amino acids in metal-affected plants. Co-treatment with E. asburiae KE17 regulated nutrient uptake by enhancing nitrogen content and inhibiting Cu and Zn accumulation in soybean plants. The results of this study suggest that E. asburiae KE17 mitigates the effects of Cu and Zn stress by reprogramming plant metabolic processes.

  14. Experimental Investigation of the Root Cause Mechanism and Effectiveness of Mitigating Actions for Axial Offset Anomaly in Pressurized Water Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Said Abdel-Khalik


    Axial offset anomaly (AOA) in pressurized water reactors refers to the presence of a significantly larger measured negative axial offset deviation than predicted by core design calculations. The neutron flux depression in the upper half of high-power rods experiencing significant subcooled boiling is believed to be caused by the concentration of boron species within the crud layer formed on the cladding surface. Recent investigations of the root-cause mechanism for AOA [1,2] suggest that boron build-up on the fuel is caused by precipitation of lithium metaborate (LiBO2) within the crud in regions of subcooled boiling. Indirect evidence in support of this hypothesis was inferred from operating experience at Callaway, where lithium return and hide-out were, respectively, observed following power reductions and power increases when AOA was present. However, direct evidence of lithium metaborate precipitation within the crud has, heretofore, not been shown because of its retrograde solubility. To this end, this investigation has been undertaken in order to directly verify or refute the proposed root-cause mechanism of AOA, and examine the effectiveness of possible mitigating actions to limit its impact in high power PWR cores.

  15. A Decision Matrix Approach to Evaluating the Impacts of Land-Use Activities Undertaken to Mitigate Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    Kueppers, L.M.; Harte, J.; Smith, M.E. [Department of Environmental Science, Policy and Management, University of California Berkeley, 151 Hilgard Hall, Berkeley, CA 94720 (United States); Baer, P. [Energy and Resources Group, University of California Berkeley, 310 Barrows Hall, Berkeley, CA 94720 (United States); Haya, B.; Koteen, L.E. [Energy and Resources Group, University of California Berkeley, 310 Barrows Hall, Berkeley, CA 94720 (United States)


    Land-use activities that affect the global balance of greenhouse gases have been a topic of intense discussion during ongoing climate change treaty negotiations. Policy mechanisms that reward countries for implementing climatically beneficial land-use practices have been included in the Bonn and Marrakech agreements on implementation of the Kyoto Protocol. However some still fear that land-use projects focused narrowly on carbon gain will result in socioeconomic and environmental harm, and thus conflict with the explicit sustainable development objectives of the agreement. We propose a policy tool, in the form of a multi-attribute decision matrix, which can be used to evaluate potential and completed land-use projects for their climate, environmental and socioeconomic impacts simultaneously. Project evaluation using this tool makes tradeoffs explicit and allows identification of projects with multiple co-benefits for promotion ahead of others. Combined with appropriate public participation, accounting, and verification policies, a land-use activity decision matrix can help ensure that progressive land management practices are an effective part of the solution to global climate change.

  16. Lessons Learned from an Industry, Government and University Collaboration to Restore Stream Habitats and Mitigate Effects (United States)

    Jones, Nicholas E.; Scrimgeour, Garry J.; Tonn, William M.


    Restoration ecologists conduct both basic and applied research using a diversity of funding and collaborative models. Over the last 17 years we have assessed the effectiveness of a stream compensation project in Canada's north, where an independent university-based research program was a condition of the regulatory approval process. This resulted in a non-traditional university-government-industry partnership. Here we share seven lessons that we learned from our collective experiences with the research partnership and use the Ekati diamond mine as a case study to illustrate and support lessons learned. Our advice includes opinions on the importance of: engaging collaborators early, defining roles and responsibilities, data sharing and standardization, the use of natural streams to set restoration targets, expect setbacks and surprises, treating restoration as an opportunity to experiment, and how to define success. Many of the lessons learned are broadly applicable to those whom embark on research collaborations among industry, universities, and consulting companies within a regulatory framework and may be of particular value to collaborators in early stages of their career.

  17. A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation

    Directory of Open Access Journals (Sweden)

    Katherine H. Carruthers


    Full Text Available Background. Radiation therapy is a form of adjuvant care used in many oncological treatment protocols. However, nonmalignant neighboring tissues are harmed as a result of this treatment. Therefore, the goal of this study was to induce the production of survivin, an antiapoptotic protein, to determine if this protein could provide protection to noncancerous cells during radiation exposure. Methods. Using a murine model, a recombinant adenoassociated virus (rAAV was used to deliver survivin to the treatment group and yellow fluorescence protein (YFP to the control group. Both groups received targeted radiation. Visual inspection, gait analysis, and tissue histology were used to determine the extent of damage caused by the radiation. Results. The YFP group demonstrated ulceration of the irradiated area while the survivin treated mice exhibited only hair loss. Histology showed that the YFP treated mice experienced dermal thickening, as well as an increase in collagen that was not present in the survivin treated mice. Gait analysis demonstrated a difference between the two groups, with the YFP mice averaging a lower speed. Conclusions. The use of gene-modification to induce survivin expression in normal tissues allows for the protection of nontarget areas from the negative side effects normally associated with ionizing radiation.

  18. National-level infrastructure and economic effects of switchgrass cofiring with coal in existing power plants for carbon mitigation. (United States)

    Morrow, William R; Griffin, W Michael; Matthews, H Scott


    We update a previously presented Linear Programming (LP) methodology for estimating state level costs for reducing CO2 emissions from existing coal-fired power plants by cofiring switchgrass, a biomass energy crop, and coal. This paper presents national level results of applying the methodology to the entire portion of the United States in which switchgrass could be grown without irrigation. We present incremental switchgrass and coal cofiring carbon cost of mitigation curves along with a presentation of regionally specific cofiring economics and policy issues. The results show that cofiring 189 million dry short tons of switchgrass with coal in the existing U.S. coal-fired electricity generation fleet can mitigate approximately 256 million short tons of carbon-dioxide (CO2) per year, representing a 9% reduction of 2005 electricity sector CO2 emissions. Total marginal costs, including capital, labor, feedstock, and transportation, range from $20 to $86/ton CO2 mitigated,with average costs ranging from $20 to $45/ton. If some existing power plants upgrade to boilers designed for combusting switchgrass, an additional 54 million tons of switchgrass can be cofired. In this case, total marginal costs range from $26 to $100/ton CO2 mitigated, with average costs ranging from $20 to $60/ton. Costs for states east of the Mississippi River are largely unaffected by boiler replacement; Atlantic seaboard states represent the lowest cofiring cost of carbon mitigation. The central plains states west of the Mississippi River are most affected by the boiler replacement option and, in general, go from one of the lowest cofiring cost of carbon mitigation regions to the highest. We explain the variation in transportation expenses and highlight regional cost of mitigation variations as transportation overwhelms other cofiring costs.

  19. Flathead Lake Angler Survey; Monitoring Activities for the Hungry Horse Fisheries Mitigation Plan, 1992-1993 Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Evarts, Les; Hansen, Barry; DosSantos, Joe (Confederated Salish and Kootenai Tribes of the Flathead Nation, Pablo, MT)


    A roving creel survey was conducted on Flathead Lake in northwestern Montana from May 17, 1992 to May 19, 1993. The primary objective of the survey was to quantify the baseline fishery and exploitation rates existing prior to Hungry Horse Dam mitigation efforts. Anglers were counted on 308 occasions, comprising 5,618 fishing boats, 515 shore anglers, and 2,191 ice anglers. The party interviews represented 4,410 anglers, made up of 2,613 boat anglers, 787 shore anglers, and 1,010 ice anglers. A total of 47,883 angler days (190,108 angler hours) of pressure and a harvest of 42,979 fish (including lake trout, lake whitefish, yellow perch, bull trout, and westslope cutthroat trout) were estimated. Pressure was distributed between shore, boat, and ice anglers as 4%, 87%, and 9%, respectively. Seventynine percent of the total effort was directed at lake trout during the study period. Limited comparisons were made to previous creel surveys on Flathead Lake due to differences in methods and radical changes in the fishery. Potential sources of bias are explained in detail. Future creel surveys must employ methods consistent with this survey to obtain estimates that are statistically distinguishable.

  20. Pileup Mitigation Techniques

    CERN Document Server

    Klein, Matthew Henry; The ATLAS collaboration


    We report on recent progress in the ATLAS experiment in developing tools to mitigate the effects of pile-up. Forward pile-up jet tagging techniques, as well as constituent-level pile-up suppression algorithms are discussed in details. The impacts of these approaches on both jet energy and angular resolution, as well as jet substructure and boosted object tagging performance are discussed. Improvements to various physics channels of interest are discussed and the potential future of such algorithms — both online and offline, and both at the current LHC and a future high-luminosity LHC and beyond — is considered in detail

  1. Mitigation : Closed Basin Project (United States)

    US Fish and Wildlife Service, Department of the Interior — The upcoming meeting on waterfowl mitigation for the Closed Basin Project will have several people talk about possible changes to the waterfowl mitigation program. A...

  2. Investigation into solar drying of potato: effect of sample geometry on drying kinetics and CO2 emissions mitigation. (United States)

    Tripathy, P P


    Drying experiments have been performed with potato cylinders and slices using a laboratory scale designed natural convection mixed-mode solar dryer. The drying data were fitted to eight different mathematical models to predict the drying kinetics, and the validity of these models were evaluated statistically through coefficient of determination (R(2)), root mean square error (RMSE) and reduced chi-square (χ (2)). The present investigation showed that amongst all the mathematical models studied, the Modified Page model was in good agreement with the experimental drying data for both potato cylinders and slices. A mathematical framework has been proposed to estimate the performance of the food dryer in terms of net CO2 emissions mitigation potential along with unit cost of CO2 mitigation arising because of replacement of different fossil fuels by renewable solar energy. For each fossil fuel replaced, the gross annual amount of CO2 as well as net amount of annual CO2 emissions mitigation potential considering CO2 emissions embodied in the manufacture of mixed-mode solar dryer has been estimated. The CO2 mitigation potential and amount of fossil fuels saved while drying potato samples were found to be the maximum for coal followed by light diesel oil and natural gas. It was inferred from the present study that by the year 2020, 23 % of CO2 emissions can be mitigated by the use of mixed-mode solar dryer for drying of agricultural products.

  3. Densified biomass can cost-effectively mitigate greenhouse gas emissions and address energy security in thermal applications. (United States)

    Wilson, Thomas O; McNeal, Frederick M; Spatari, Sabrina; G Abler, David; Adler, Paul R


    Regional supplies of biomass are currently being evaluated as feedstocks in energy applications to meet renewable portfolio (RPS) and low carbon fuel standards. We investigate the life cycle greenhouse gas (GHG) emissions and associated abatement costs resulting from using densified switchgrass for thermal and electrical energy. In contrast to the large and positive abatement costs for using biomass in electricity generation ($149/Mg CO(2)e) due to the low cost of coal and high feedstock and power plant operation costs, abatement costs for replacing fuel oil with biomass in thermal applications are large and negative (-$52 to -$92/Mg CO(2)e), resulting in cost savings. Replacing fuel oil with biomass in thermal applications results in least cost reductions compared to replacing coal in electricity generation, an alternative that has gained attention due to RPS legislation and the centralized production model most often considered in U.S. policy. Our estimates indicate a more than doubling of liquid fuel displacement when switchgrass is substituted for fuel oil as opposed to gasoline, suggesting that, in certain U.S. locations, such as the northeast, densified biomass would help to significantly decarbonize energy supply with regionally sourced feedstock, while also reducing imported oil. On the basis of supply projections from the recently released Billion Ton Report, there will be enough sustainably harvested biomass available in the northeast by 2022 to offset the entirety of heating oil demand in the same region. This will save NE consumers between $2.3 and $3.9 billion annually. Diverting the same resource to electricity generation would cost the region $7.7 billion per year. While there is great need for finding low carbon substitutes for coal power and liquid transportation fuels in the U.S., we argue that in certain regions it makes cost- (and GHG mitigation-) effective sense to phase out liquid heating fuels with locally produced biomass first.

  4. Greenhouse gas emissions from solid waste in Beijing: The rising trend and the mitigation effects by management improvements. (United States)

    Yu, Yongqiang; Zhang, Wen


    Disposal of solid waste poses great challenges to city managements. Changes in solid waste composition and disposal methods, along with urbanisation, can certainly affect greenhouse gas emissions from municipal solid waste. In this study, we analysed the changes in the generation, composition and management of municipal solid waste in Beijing. The changes of greenhouse gas emissions from municipal solid waste management were thereafter calculated. The impacts of municipal solid waste management improvements on greenhouse gas emissions and the mitigation effects of treatment techniques of greenhouse gas were also analysed. Municipal solid waste generation in Beijing has increased, and food waste has constituted the most substantial component of municipal solid waste over the past decade. Since the first half of 1950s, greenhouse gas emission has increased from 6 CO2-eq Gg y(-1)to approximately 200 CO2-eq Gg y(-1)in the early 1990s and 2145 CO2-eq Gg y(-1)in 2013. Landfill gas flaring, landfill gas utilisation and energy recovery in incineration are three techniques of the after-emission treatments in municipal solid waste management. The scenario analysis showed that three techniques might reduce greenhouse gas emissions by 22.7%, 4.5% and 9.8%, respectively. In the future, if waste disposal can achieve a ratio of 4:3:3 by landfill, composting and incineration with the proposed after-emission treatments, as stipulated by the Beijing Municipal Waste Management Act, greenhouse gas emissions from municipal solid waste will decrease by 41%.

  5. Long-Term Field Data and Climate-Habitat Models Show That Orangutan Persistence Depends on Effective Forest Management and Greenhouse Gas Mitigation


    Stephen D Gregory; Brook, Barry W.; Goossens, Benoît; Ancrenaz, Marc; Alfred, Raymond; Ambu, Laurentius N.; Fordham, Damien A.


    Background Southeast Asian deforestation rates are among the world’s highest and threaten to drive many forest-dependent species to extinction. Climate change is expected to interact with deforestation to amplify this risk. Here we examine whether regional incentives for sustainable forest management will be effective in improving threatened mammal conservation, in isolation and when combined with global climate change mitigation. Methodology/Principal Findings Using a long time-series of ora...

  6. A regional classification of the effectiveness of depressional wetlands at mitigating nitrogen transport to surface waters in the Northern Atlantic Coastal Plain (United States)

    Ator, Scott W.; Denver, Judith M.; LaMotte, Andrew E.; Sekellick, Andrew J.


    Nitrogen from nonpoint sources contributes to eutrophication, hypoxia, and related ecological degradation in Atlantic Coastal Plain streams and adjacent coastal estuaries such as Chesapeake Bay and Pamlico Sound. Although denitrification in depressional (non-riparian) wetlands common to the Coastal Plain can be a significant landscape sink for nitrogen, the effectiveness of individual wetlands at removing nitrogen varies substantially due to varying hydrogeologic, geochemical, and other landscape conditions, which are often poorly or inconsistently mapped over large areas. A geographic model describing the spatial variability in the likely effectiveness of depressional wetlands in watershed uplands at mitigating nitrogen transport from nonpoint sources to surface waters was constructed for the Northern Atlantic Coastal Plain (NACP), from North Carolina through New Jersey. Geographic and statistical techniques were used to develop the model. Available medium-resolution (1:100,000-scale) stream hydrography was used to define 33,799 individual watershed catchments in the study area. Sixteen landscape metrics relevant to the occurrence of depressional wetlands and their effectiveness as nitrogen sinks were defined for each catchment, based primarily on available topographic and soils data. Cluster analysis was used to aggregate the 33,799 catchments into eight wetland landscape regions (WLRs) based on the value of three principal components computed for the 16 original landscape metrics. Significant differences in topography, soil, and land cover among the eight WLRs demonstrate the effectiveness of the clustering technique. Results were used to interpret the relative likelihood of depressional wetlands in each WLR and their likely effectiveness at mitigating nitrogen transport from upland source areas to surface waters. The potential effectiveness of depressional wetlands at mitigating nitrogen transport varies substantially over different parts of the NACP

  7. Active Flow Control (AFC) and Insect Accretion and Mitigation (IAM) System Design and Integration on the Boeing 757 ecoDemonstrator (United States)

    Alexander, Michael G.; Harris, F. Keith; Spoor, Marc A.; Boyland, Susannah R.; Farrell, Thomas E.; Raines, David M.


    This paper presents a systems overview of how the Boeing and NASA team designed, analyzed, fabricated, and integrated the Active Flow Control (AFC) technology and Insect Accretion Mitigation (IAM) systems on the Boeing 757 ecoDemonstrator. The NASA Environmentally Responsible Aviation (ERA) project partnered with Boeing to demonstrate these two technology systems on a specially outfitted Boeing 757 ecoDemonstrator during the spring of 2015. The AFC system demonstrated attenuation of flow separation on a highly deflected rudder and increased the side force generated. This AFC system may enable a smaller vertical tail to provide the control authority needed in the event of an engine failure during takeoff while still operating in a conventional manner over the rest of the flight envelope. The AFC system consisted of ducting to obtain air from the Auxiliary Power Unit (APU), a control valve to modulate the system mass flow, a heat exchanger to lower the APU air temperature, and additional ducting to deliver the air to the AFC actuators located on the vertical tail. The IAM system demonstrated how to mitigate insect residue adhesion on a wing's leading edge. Something as small as insect residue on a leading edge can cause turbulent wedges that interrupt laminar flow, resulting in an increase in drag and fuel use. The IAM system consisted of NASA developed Engineered Surfaces (ES) which were thin aluminum sheet substrate panels with coatings applied to the exterior. These ES were installed on slats 8 and 9 on the right wing of the 757 ecoDemonstrator. They were designed to support panel removal and installation in one crew shift. Each slat accommodated 4 panels. Both the AFC and IAM flight test were the culmination of several years of development and produced valuable data for the advancement of modern aircraft designs.

  8. Mitigation of nonlinear effects through frequency shift free mid-span spectral inversion using counter-propagating dual pumped FWM in fiber (United States)

    Anchal, Abhishek; Kumar, Pradeep; Landais, Pascal


    We propose and numerically verify a scheme of frequency-shift free mid-span spectral inversion (MSSI) for nonlinearity mitigation in an optical transmission system. Spectral inversion is accomplished by optical phase conjugation, realized by counter-propagating dual pumped four-wave mixing in a highly nonlinear fiber. We examine the performance of MSSI due to critical parameters such as nonlinear fiber length, pump and signal power. We demonstrate the near complete nonlinearity mitigation of 40 Gbps DQPSK modulated data transmitted over 1000 km standard single mode fiber using our method of MSSI. We perform simulation of bit-error rate as a function of optical signal to noise ratio to corroborate the effect of frequency-shift free MSSI.

  9. Safety Design Requirements for Active Hazard Mitigation Device (AHMD) Employed to Address Fast and Slow Cook-off Thermal Threats (United States)


    DOD Fuze Engineering Standardization Working Group U.S. Army Armament Research, Development, and Engineering Center ATTN: RDAR-EIZ / Building 6...ACTIVITY: DOD Fuze Engineering Standardization Working Group U.S. Army Armament Research, Development, and Engineering Center ATTN: RDAR-EIZ...addressed to: Chairman, DOD Fuze Engineering Standardization Working Group, U.S. Army Armament Research, Development, and Engineering Center (RDAR

  10. A Parametric Optimization Approach to Mitigating the Urban Heat Island Effect: A Case Study in Ancona, Italy

    Directory of Open Access Journals (Sweden)

    Roberta Cocci Grifoni


    Full Text Available The aim of this paper is to identify a parameterization method that considers existing connections and relationships between traditional indicators of environmental sustainability as a step in combating climate change via urban strategies. A typical Mediterranean city (Ancona, Italy is investigated with a multi-objective optimization platform called modeFrontier, which uses Pareto optimality. This concept formalizes the trade-off between a given set of mutually contradicting objectives, such as high thermal comfort and low energy consumption, to identify a set of Pareto solutions. A solution is Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the others. The optimization process employs given constraints (for example, meteorological scenarios with high temperature and low winds or morphological building parameters, custom procedural algorithms (recursive algorithms to generate the set of all non-dominated objective parameters, and genetic algorithms (inspired by the natural selection process to examine a wide urban space and identify interesting relationships among relevant variables for typical summer scenarios. Multi-objective optimizers involve many evaluations of two objectives (i.e., energy consumption and thermal comfort in this study while considering many analytical constraints. This approach entails a considerably more exhaustive search of environmental variables that can help the urban planning process to mitigate the urban heat island (UHI effect. Three quantitative metrics related to urban morphology and local climate conditions, as well as a thermal comfort indicator (the predicted mean vote, are defined and applied to Ancona to examine the potential for new sustainability in urban design. The results show that two parameters examined—compacity and a building-scale energy indicator—can offer insight when designing comfortable cities, while a citywide energy indicator shows

  11. Monitoring volcanic activity with satellite remote sensing to reduce aviation hazard and mitigate the risk: application to the North Pacific (United States)

    Webley, P. W.; Dehn, J.


    Volcanic activity across the North Pacific (NOPAC) occurs on a daily basis and as such monitoring needs to occur on a 24 hour, 365 days a year basis. The risk to the local population and aviation traffic is too high for this not to happen. Given the size and remoteness of the NOPAC region, satellite remote sensing has become an invaluable tool to monitor the ground activity from the regions volcanoes as well as observe, detect and analyze the volcanic ash clouds that transverse across the Pacific. Here, we describe the satellite data collection, data analysis, real-time alert/alarm systems, observational database and nearly 20-year archive of both automated and manual observations of volcanic activity. We provide examples of where satellite remote sensing has detected precursory activity at volcanoes, prior to the volcanic eruption, as well as different types of eruptive behavior that can be inferred from the time series data. Additionally, we illustrate how the remote sensing data be used to detect volcanic ash in the atmosphere, with some of the pro's and con's to the method as applied to the NOPAC, and how the data can be used with other volcano monitoring techniques, such as seismic monitoring and infrasound, to provide a more complete understanding of a volcanoes behavior. We focus on several large volcanic events across the region, since our archive started in 1993, and show how the system can detect both these large scale events as well as the smaller in size but higher in frequency type events. It's all about how to reduce the risk, improve scenario planning and situational awareness and at the same time providing the best and most reliable hazard assessment from any volcanic activity.

  12. Mitigating Higher Ed Cyber Attacks (United States)

    Rogers, Gary; Ashford, Tina


    In this presentation we will discuss the many and varied cyber attacks that have recently occurred in the higher ed community. We will discuss the perpetrators, the victims, the impact and how these institutions have evolved to meet this threat. Mitigation techniques and defense strategies will be covered as will a discussion of effective security…

  13. Remote ischemic preconditioning mitigates myocardial and neurological dysfunction via K(ATP) channel activation in a rat model of hemorrhagic shock. (United States)

    Hu, Xianwen; Yang, Zhengfei; Yang, Min; Qian, Jie; Cahoon, Jena; Xu, Jiefeng; Sun, Shijie; Tang, Wanchun


    Severe hemorrhagic shock and resuscitation is a state of global body ischemia and reperfusion that causes myocardial and cerebral dysfunction. We investigated whether remote ischemic preconditioning (RIPC) would reduce myocardial and cerebral ischemia and reperfusion injuries after hemorrhagic shock as the result of the K(ATP) channel activation. Twenty-one male rats were randomized into three groups: RIPC, RIPC with K(ATP) channel blocker, and control. Remote ischemic preconditioning was induced by four cycles of 5 min of limb ischemia followed by reperfusion for 5 min. Hemorrhagic shock was induced by removing 50% of the estimated total blood volume during an interval of 1 h. Thirty minutes after the completion of bleeding, the animals were reinfused with shed blood during the ensuing 30 min. The animals were monitored for 2 h and observed for an additional 72 h. Myocardial function was measured by echocardiography, and sublingual microcirculation was measured by a sidestream dark-field imaging device at baseline, 1 h after bleeding, 30 min after the completion of bleeding, 30 min after reinfusion, and hourly intervals thereafter. The survival and neurological function were evaluated at 12, 24, 48, and 72 h after reinfusion. At 2 h after reinfusion, ejection fraction and myocardial performance index were significantly better in the RIPC group than in the control group (P shock and resuscitation, RIPC mitigated myocardial and neurological dysfunction with improved survival by activation of the K(ATP) channel.

  14. Economics of Tsunami Mitigation in the Pacific Northwest (United States)

    Goettel, K. A.; Rizzo, A.; Sigrist, D.; Bernard, E. N.


    The death total in a major Cascadia Subduction Zone (CSZ) tsunami may be comparable to the Tohoku tsunami - tens of thousands. To date, tsunami risk reduction activities have been almost exclusively hazard mapping and evacuation planning. Reducing deaths in locations where evacuation to high ground is impossible in the short time between ground shaking and arrival of tsunamis requires measures such as vertical evacuation facilities or engineered pathways to safe ground. Yet, very few, if any, such tsunami mitigation projects have been done. In contrast, many tornado safe room and earthquake mitigation projects driven entirely or in largely by life safety have been done with costs in the billions of dollars. The absence of tsunami mitigation measures results from the belief that tsunamis are too infrequent and the costs too high to justify life safety mitigation measures. A simple analysis based on return periods, death rates, and the geographic distribution of high risk areas for these hazards demonstrates that this belief is incorrect: well-engineered tsunami mitigation projects are more cost-effective with higher benefit-cost ratios than almost all tornado or earthquake mitigation projects. Goldfinger's paleoseismic studies of CSZ turbidites indicate return periods for major CSZ tsunamis of about 250-500 years (USGS Prof. Paper 1661-F in press). Tsunami return periods are comparable to those for major earthquakes at a given location in high seismic areas and are much shorter than those for tornados at any location which range from >4,000 to >16,000 years for >EF2 and >EF4 tornadoes, respectively. The average earthquake death rate in the US over the past 100-years is about 1/year, or about 30/year including the 1906 San Francisco earthquake. The average death rate for tornadoes is about 90/year. For CSZ tsunamis, the estimated average death rate ranges from about 20/year (10,000 every 500 years) to 80/year (20,000 every 250 years). Thus, the long term deaths rates

  15. Mitigating effects of L-selenomethionine on low-dose iron ion radiation-induced changes in gene expression associated with cellular stress. (United States)

    Nuth, Manunya; Kennedy, Ann R


    Ionizing radiation associated with highly energetic and charged heavy (HZE) particles poses a danger to astronauts during space travel. The aim of the present study was to evaluate the patterns of gene expression associated with cellular exposure to low-dose iron ion irradiation, in the presence and absence of L-selenomethionine (SeM). Human thyroid epithelial cells (HTori-3) were exposed to low-dose iron ion (1 GeV/n) irradiation at 10 or 20 cGy with or without SeM pretreatment. The cells were harvested 6 and 16 h post-irradiation and analyzed by the Affymetrix U133Av2 gene chip arrays. Genes exhibiting a 1.5-fold expression cut-off and 5% false discovery rate (FDR) were considered statistically significant and subsequently analyzed using the Database for Annotation, Visualization and Integrated Discovery (DAVID) for pathway analysis. Representative genes were further validated by real-time RT-PCR. Even at low doses of radiation from iron ions, global genome profiling of the irradiated cells revealed the upregulation of genes associated with the activation of stress-related signaling pathways (ubiquitin-mediated proteolysis, p53 signaling, cell cycle and apoptosis), which occurred in a dose-dependent manner. A 24-h pretreatment with SeM was shown to reduce the radiation effects by mitigating stress-related signaling pathways and downregulating certain genes associated with cell adhesion. The mechanism by which SeM prevents radiation-induced transformation in vitro may involve the suppression of the expression of genes associated with stress-related signaling and certain cell adhesion events.

  16. Design and calibration of a semi-active control logic to mitigate structural vibrations in wind turbines

    DEFF Research Database (Denmark)

    Caterino, Nicola; Georgakis, Christos T.; Spizzuoco, Mariacristina;


    than ever. The main objective is limiting bending moment demand by relaxing the base restraint, without increasing the top displacement, so reducing the incidence of harmful "p-delta" effects. A variable restraint at the base, able to modify in real time its mechanical properties according...

  17. Silicon Mitigates Salinity Stress by Regulating the Physiology, Antioxidant Enzyme Activities, and Protein Expression in Capsicum annuum 'Bugwang'. (United States)

    Manivannan, Abinaya; Soundararajan, Prabhakaran; Muneer, Sowbiya; Ko, Chung Ho; Jeong, Byoung Ryong


    Silicon- (Si-) induced salinity stress resistance was demonstrated at physiological and proteomic levels in Capsicum annuum for the first time. Seedlings of C. annuum were hydroponically treated with NaCl (50 mM) with or without Si (1.8 mM) for 15 days. The results illustrated that saline conditions significantly reduced plant growth and biomass and photosynthetic parameters and increased the electrolyte leakage potential, lipid peroxidation, and hydrogen peroxide level. However, supplementation of Si allowed the plants to recover from salinity stress by improving their physiology and photosynthesis. During salinity stress, Si prevented oxidative damage by increasing the activities of antioxidant enzymes. Furthermore, Si supplementation recovered the nutrient imbalance that had occurred during salinity stress. Additionally, proteomic analysis by two-dimensional gel electrophoresis (2DE) followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) revealed that Si treatment upregulated the accumulation of proteins involved in several metabolic processes, particularly those associated with nucleotide binding and transferase activity. Moreover, Si modulated the expression of vital proteins involved in ubiquitin-mediated nucleosome pathway and carbohydrate metabolism. Overall, the results illustrate that Si application induced resistance against salinity stress in C. annuum by regulating the physiology, antioxidant metabolism, and protein expression.

  18. Defense Health Care: DOD Needs to Clarify Policies Related to Occupational and Environmental Health Surveillance and Monitor Risk Mitigation Activities (United States)


    and environmental health surveillance OEHSA Occupational and Environmental Health Site Assessment POEMS Periodic Occupational and...inhalation from burn pits in Iraq and Afghanistan, the Institute of Medicine was unable to determine whether long -term health effects are likely to result...Washington, D.C.: May 1, 2012). 5See Institute of Medicine for the Department of Veterans’ Affairs. Long -Term Health Consequences of Exposure to Burn

  19. Pilot-scale evaluation of ozone and biological activated carbon for trace organic contaminant mitigation and disinfection. (United States)

    Gerrity, Daniel; Gamage, Sujanie; Holady, Janie C; Mawhinney, Douglas B; Quiñones, Oscar; Trenholm, Rebecca A; Snyder, Shane A


    In an effort to validate the use of ozone for contaminant oxidation and disinfection in water reclamation, extensive pilot testing was performed with ozone/H(2)O(2) and biological activated carbon (BAC) at the Reno-Stead Water Reclamation Facility in Reno, Nevada. Three sets of samples were collected over a five-month period of continuous operation, and these samples were analyzed for a suite of trace organic contaminants (TOrCs), total estrogenicity, and several microbial surrogates, including the bacteriophage MS2, total and fecal coliforms, and Bacillus spores. Based on the high degree of microbial inactivation and contaminant destruction, this treatment train appears to be a viable alternative to the standard indirect potable reuse (IPR) configuration (i.e., membrane filtration, reverse osmosis, UV/H(2)O(2), and aquifer injection), particularly for inland applications where brine disposal is an issue. Several issues, including regrowth of coliform bacteria in the BAC process, must be addressed prior to full-scale implementation.

  20. The influence of mitigation on sage-grouse habitat selection within an energy development field. (United States)

    Fedy, Bradley C; Kirol, Christopher P; Sutphin, Andrew L; Maechtle, Thomas L


    Growing global energy demands ensure the continued growth of energy development. Energy development in wildlife areas can significantly impact wildlife populations. Efforts to mitigate development impacts to wildlife are on-going, but the effectiveness of such efforts is seldom monitored or assessed. Greater sage-grouse (Centrocercus urophasianus) are sensitive to energy development and likely serve as an effective umbrella species for other sagebrush-steppe obligate wildlife. We assessed the response of birds within an energy development area before and after the implementation of mitigation action. Additionally, we quantified changes in habitat distribution and abundance in pre- and post-mitigation landscapes. Sage-grouse avoidance of energy development at large spatial scales is well documented. We limited our research to directly within an energy development field in order to assess the influence of mitigation in close proximity to energy infrastructure. We used nest-location data (n = 488) within an energy development field to develop habitat selection models using logistic regression on data from 4 years of research prior to mitigation and for 4 years following the implementation of extensive mitigation efforts (e.g., decreased activity, buried powerlines). The post-mitigation habitat selection models indicated less avoidance of wells (well density β = 0.18 ± 0.08) than the pre-mitigation models (well density β = -0.09 ± 0.11). However, birds still avoided areas of high well density and nests were not found in areas with greater than 4 wells per km2 and the majority of nests (63%) were located in areas with ≤ 1 well per km2. Several other model coefficients differed between the two time periods and indicated stronger selection for sagebrush (pre-mitigation β = 0.30 ± 0.09; post-mitigation β = 0.82 ± 0.08) and less avoidance of rugged terrain (pre-mitigation β = -0.35 ± 0.12; post-mitigation β = -0.05 ± 0.09). Mitigation efforts implemented may

  1. The influence of mitigation on sage-grouse habitat selection within an energy development field.

    Directory of Open Access Journals (Sweden)

    Bradley C Fedy

    Full Text Available Growing global energy demands ensure the continued growth of energy development. Energy development in wildlife areas can significantly impact wildlife populations. Efforts to mitigate development impacts to wildlife are on-going, but the effectiveness of such efforts is seldom monitored or assessed. Greater sage-grouse (Centrocercus urophasianus are sensitive to energy development and likely serve as an effective umbrella species for other sagebrush-steppe obligate wildlife. We assessed the response of birds within an energy development area before and after the implementation of mitigation action. Additionally, we quantified changes in habitat distribution and abundance in pre- and post-mitigation landscapes. Sage-grouse avoidance of energy development at large spatial scales is well documented. We limited our research to directly within an energy development field in order to assess the influence of mitigation in close proximity to energy infrastructure. We used nest-location data (n = 488 within an energy development field to develop habitat selection models using logistic regression on data from 4 years of research prior to mitigation and for 4 years following the implementation of extensive mitigation efforts (e.g., decreased activity, buried powerlines. The post-mitigation habitat selection models indicated less avoidance of wells (well density β = 0.18 ± 0.08 than the pre-mitigation models (well density β = -0.09 ± 0.11. However, birds still avoided areas of high well density and nests were not found in areas with greater than 4 wells per km2 and the majority of nests (63% were located in areas with ≤ 1 well per km2. Several other model coefficients differed between the two time periods and indicated stronger selection for sagebrush (pre-mitigation β = 0.30 ± 0.09; post-mitigation β = 0.82 ± 0.08 and less avoidance of rugged terrain (pre-mitigation β = -0.35 ± 0.12; post-mitigation β = -0.05 ± 0.09. Mitigation efforts

  2. Climate adaptation as mitigation: the case of agricultural investments (United States)

    Lobell, David B.; Baldos, Uris Lantz C.; Hertel, Thomas W.


    Successful adaptation of agriculture to ongoing climate changes would help to maintain productivity growth and thereby reduce pressure to bring new lands into agriculture. In this paper we investigate the potential co-benefits of adaptation in terms of the avoided emissions from land use change. A model of global agricultural trade and land use, called SIMPLE, is utilized to link adaptation investments, yield growth rates, land conversion rates, and land use emissions. A scenario of global adaptation to offset negative yield impacts of temperature and precipitation changes to 2050, which requires a cumulative 225 billion USD of additional investment, results in 61 Mha less conversion of cropland and 15 Gt carbon dioxide equivalent (CO2e) fewer emissions by 2050. Thus our estimates imply an annual mitigation co-benefit of 0.35 GtCO2e yr-1 while spending 15 per tonne CO2e of avoided emissions. Uncertainty analysis is used to estimate a 5-95% confidence interval around these numbers of 0.25-0.43 Gt and 11-22 per tonne CO2e. A scenario of adaptation focused only on Sub-Saharan Africa and Latin America, while less costly in aggregate, results in much smaller mitigation potentials and higher per tonne costs. These results indicate that although investing in the least developed areas may be most desirable for the main objectives of adaptation, it has little net effect on mitigation because production gains are offset by greater rates of land clearing in the benefited regions, which are relatively low yielding and land abundant. Adaptation investments in high yielding, land scarce regions such as Asia and North America are more effective for mitigation. To identify data needs, we conduct a sensitivity analysis using the Morris method (Morris 1991 Technometrics 33 161-74). The three most critical parameters for improving estimates of mitigation potential are (in descending order) the emissions factors for converting land to agriculture, the price elasticity of land supply

  3. 2008 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report

    Energy Technology Data Exchange (ETDEWEB)

    C. T. Lindsey; K. A. Gano


    The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act cleanup of National Priorities List waste sites at Hanford. This report documents the results of revegetation and mitigation monitoring conducted in 2008 and includes 22 revegetation/restoration projects, one revegetation/mitigation project, and two bat habitat mitigation projects.

  4. 2007 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report

    Energy Technology Data Exchange (ETDEWEB)

    K. A. Gano; C. T. Lindsey


    The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) cleanup of National Priorities List waste sites at Hanford. This report documents the results of revegetation and mitigation monitoring conducted in 2007 and includes 11 revegetation/restoration projects, one revegetation/mitigation project, and 3 bat habitat mitigation projects.

  5. Wildlife mitigation and monitoring report Gunnison, Colorado, site

    Energy Technology Data Exchange (ETDEWEB)



    The Uranium Mill Tailings Remedial Action (UMTRA) Project is administered by the U.S. Department of Energy (DOE); its purpose is to cleanup uranium mill tailings and other contaminated material at 24 UMTRA Project sites in 10 states. This report summarizes the wildlife mitigation and monitoring program under way at the Gunnison UMTRA Project, Gunnison, Colorado. Remedial action at the Gunnison site was completed in December 1995 and is described in detail in the Gunnison completion report. The impacts of this activity were analyzed in the Gunnison environmental assessment (EA). These impacts included two important game species: the pronghorn antelope (Antilocapra americans) and sage grouse (Wentrocerus urophasianus). Haul truck traffic was predicted to limit antelope access to water sources north of the Tenderfoot Mountain haul road and that truck traffic along this and other haul roads could result in antelope road kills. Clearing land at the disposal cell, haul road and borrow site activities, and the associated human activities also were predicted to negatively impact (directly and indirectly) sage grouse breeding, nesting, loafing, and wintering habitat. As a result, an extensive mitigation and monitoring plan began in 1992. Most of the monitoring studies are complete and the results of these studies, written by different authors, appear in numerous reports. This report will: (1) Analyze existing impacts and compare them to predicted impacts. (2) Summarize mitigation measures. (3) Summarize all existing monitoring data in one report. (4) Analyze the effectiveness of the mitigation measures.

  6. Threatened Caribbean coral is able to mitigate the adverse effects of ocean acidification on calcification by increasing feeding rate.

    Directory of Open Access Journals (Sweden)

    Erica K Towle

    Full Text Available Global climate change threatens coral growth and reef ecosystem health via ocean warming and ocean acidification (OA. Whereas the negative impacts of these stressors are increasingly well-documented, studies identifying pathways to resilience are still poorly understood. Heterotrophy has been shown to help corals experiencing decreases in growth due to either thermal or OA stress; however, the mechanism by which it mitigates these decreases remains unclear. This study tested the ability of coral heterotrophy to mitigate reductions in growth due to climate change stress in the critically endangered Caribbean coral Acropora cervicornis via changes in feeding rate and lipid content. Corals were either fed or unfed and exposed to elevated temperature (30°C, enriched pCO2 (800 ppm, or both (30°C/800 ppm as compared to a control (26°C/390 ppm for 8 weeks. Feeding rate and lipid content both increased in corals experiencing OA vs. present-day conditions, and were significantly correlated. Fed corals were able to maintain ambient growth rates at both elevated temperature and elevated CO2, while unfed corals experienced significant decreases in growth with respect to fed conspecifics. Our results show for the first time that a threatened coral species can buffer OA-reduced calcification by increasing feeding rates and lipid content.

  7. Threatened Caribbean coral is able to mitigate the adverse effects of ocean acidification on calcification by increasing feeding rate. (United States)

    Towle, Erica K; Enochs, Ian C; Langdon, Chris


    Global climate change threatens coral growth and reef ecosystem health via ocean warming and ocean acidification (OA). Whereas the negative impacts of these stressors are increasingly well-documented, studies identifying pathways to resilience are still poorly understood. Heterotrophy has been shown to help corals experiencing decreases in growth due to either thermal or OA stress; however, the mechanism by which it mitigates these decreases remains unclear. This study tested the ability of coral heterotrophy to mitigate reductions in growth due to climate change stress in the critically endangered Caribbean coral Acropora cervicornis via changes in feeding rate and lipid content. Corals were either fed or unfed and exposed to elevated temperature (30°C), enriched pCO2 (800 ppm), or both (30°C/800 ppm) as compared to a control (26°C/390 ppm) for 8 weeks. Feeding rate and lipid content both increased in corals experiencing OA vs. present-day conditions, and were significantly correlated. Fed corals were able to maintain ambient growth rates at both elevated temperature and elevated CO2, while unfed corals experienced significant decreases in growth with respect to fed conspecifics. Our results show for the first time that a threatened coral species can buffer OA-reduced calcification by increasing feeding rates and lipid content.

  8. Investigation of radon entry and effectiveness of mitigation measures in seven houses in New Jersey: Midproject report

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, T.G.; Dudney, C.S.; Monar, K.P.; Landguth, D.C.; Wilson, D.L.; Hawthorne, A.R.; Hubbard, L.M.; Gadsby, K.J.; Bohac, D.L.; Decker, C.A.


    A detailed radon mitigation study is in progress in 14 homes in the New Jersey Piedmont area. The principal goals are the refinement of diagnostic measurements for selection and implementation of mitigation systems, and the reduction of radon concentrations to acceptable levels inside the study houses. Monitoring stations were installed in each home in October, 1986. Instrumented measurements included: basement and upstairs radon; differential pressures across the basement/subslag, basement/upstairs and basement/outdoor interfaces; temperatures at basement, upstairs and outdoor locations; and central air handler usage. A weather station was located at one house, monitoring wind speed and direction; barometric pressure; precipitation; soil temperature; and outdoor temperature and relative humidity. A time-averaged value of all of the above parameters was recorded every 30 min. Several additional parameters were monitored on an intermittent basis in all or selected homes. These include multizone air infiltration rates which have been measured in all homes using passive perfluorocarbon tracers (PFT) and in two homes using a constant concentration tracer gas system (CCTG). Total radon progeny, soil gas radon concentration and permeability characteristics, and gamma radiation levels were also monitored periodically in all study homes. 10 refs., 53 figs.

  9. Space Debris & its Mitigation (United States)

    Kaushal, Sourabh; Arora, Nishant


    Space debris has become a growing concern in recent years, since collisions at orbital velocities can be highly damaging to functioning satellites and can also produce even more space debris in the process. Some spacecraft, like the International Space Station, are now armored to deal with this hazard but armor and mitigation measures can be prohibitively costly when trying to protect satellites or human spaceflight vehicles like the shuttle. This paper describes the current orbital debris environment, outline its main sources, and identify mitigation measures to reduce orbital debris growth by controlling these sources. We studied the literature on the topic Space Debris. We have proposed some methods to solve this problem of space debris. We have also highlighted the shortcomings of already proposed methods by space experts and we have proposed some modification in those methods. Some of them can be very effective in the process of mitigation of space debris, but some of them need some modification. Recently proposed methods by space experts are maneuver, shielding of space elevator with the foil, vaporizing or redirecting of space debris back to earth with the help of laser, use of aerogel as a protective layer, construction of large junkyards around international space station, use of electrodynamics tether & the latest method proposed is the use of nano satellites in the clearing of the space debris. Limitations of the already proposed methods are as follows: - Maneuvering can't be the final solution to our problem as it is the act of self-defence. - Shielding can't be done on the parts like solar panels and optical devices. - Vaporizing or redirecting of space debris can affect the human life on earth if it is not done in proper manner. - Aerogel has a threshold limit up to which it can bear (resist) the impact of collision. - Large junkyards can be effective only for large sized debris. In this paper we propose: A. The Use of Nano Tubes by creating a mesh

  10. Simulation study of HEMT structures with HfO{sub 2} cap layer for mitigating inverse piezoelectric effect related device failures

    Energy Technology Data Exchange (ETDEWEB)

    Nagulapally, Deepthi; Joshi, Ravi P., E-mail: [Department of Electrical and Computer Engineering, Old Dominion University, Norfolk, VA 23529-0246 (United States); Pradhan, Aswini [Department of Engineering and Center for Materials Research, Norfolk State University, 700 Park Avenue, Norfolk, VA 23504 (United States)


    The Inverse Piezoelectric Effect (IPE) is thought to contribute to possible device failure of GaN High Electron Mobility Transistors (HEMTs). Here we focus on a simulation study to probe the possible mitigation of the IPE by reducing the internal electric fields and related elastic energy through the use of high-k materials. Inclusion of a HfO{sub 2} “cap layer” above the AlGaN barrier particularly with a partial mesa structure is shown to have potential advantages. Simulations reveal even greater reductions in the internal electric fields by using “field plates” in concert with high-k oxides.

  11. FEMA Hazard Mitigation Assistance Flood Mitigation Assistance (FMA) Data (United States)

    Department of Homeland Security — This dataset contains closed and obligated projects funded under the following Hazard Mitigation Assistance (HMA) grant programs: Flood Mitigation Assistance (FMA)....

  12. Towards an integrated scientific approach for carbon accounting in forestry. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland. 28-30 Sep 2000

    Directory of Open Access Journals (Sweden)

    Karjalainen T.


    Full Text Available In the COST E21-Action ""Contribution of Forests and Forestry to Mitigate Greenhouse Effects"", emphasis is put on the quantification of carbon storage in the forest ecosystems and on the understanding of linkages between human activities and climate change, particularly the role of forests and forestry. COST E21 integrates natural, socio-economic as well as methodological aspects relevant for reporting under the unitéd Nations Framework Convention on Climate Change and the Kyoto Protocol, as well as decision-making at the European level in the context of carbon mitigation in forest ecosystems. This Action is a pioneering attempt to co-ordinate research: to exchange experience and knowledge towards standardised greenhouse gas inventory accounting for forests over Europe. It will match, within four years (1999-2003, both scientific and political agendas. This paper gives a background presentation of the COST E21-Action, its work plan and its clearing house. It finally gives the outline of country specific information to the COST E21 as presented in this issue in a standard format.

  13. Effect of different molecular weight chitosans on the mitigation of acrylamide formation and the functional properties of the resultant Maillard reaction products. (United States)

    Chang, Yu-Wei; Sung, Wen-Chieh; Chen, Jing-Yi


    Mitigation of acrylamide formation and the functional properties of Maillard reaction products (MRPs) were investigated in a food model system. The system was composed of elements of mixtures and their combination including fructose, asparagine and different molecular weight chitosans. All solutions were heated, and then analyzed for acrylamide content, MRPs absorbance, pH, color, antioxidant capacity, antibacterial activity and kinematic viscosity. The fructose, asparagine and chitosan mixture had more MRPs compared to other mixtures. 1,1-Diphenyl-2-pricrylhydrazy (DPPH) radical scavenging activities, ferrous ion chelating abilities and reducing power results showed that all solutions containing a combination of two or three reactants had antioxidant capacities. Acrylamide content has a positive correlation with absorbance values at OD294 and OD420 but a negative correlation with the CIB L(∗) value of a solution (pacrylamide.

  14. Beach characteristics mitigate effects of onshore wind on horseshoe crab spawning: Implications for matching with shorebird migration in Delaware Bay (United States)

    Smith, D.R.; Jackson, N.L.; Nordstrom, K.F.; Weber, R.G.


    Disruption of food availability by unfavorable physical processes at energetically demanding times can limit recruitment of migratory species as predicted by the match-mismatch hypothesis. Identification and protection of disruption-resistant habitat could contribute to system resilience. For example, horseshoe crab Limulus polyphemus spawning and shorebird stopover must match temporally in Delaware Bay for eggs to be available to shorebirds. Onshore winds that generate waves can create a mismatch by delaying horseshoe crab spawning. We examined effects of beach characteristics and onshore winds on spawning activity at five beaches when water temperatures were otherwise consistent with early spawning activity. Onshore winds resulted in reduced spawning activity during the shorebird stopover, when spawning typically peaks in late May. During the period with high onshore wind, egg density was highest on the foreshore exposed to the lowest wave heights. Onshore wind was low in early June, and spawning and egg densities were high at all sites, but shorebirds had departed. Beaches that can serve as a refuge from wind and waves can be identified by physical characteristics and orientation to prevailing winds and should receive special conservation status, especially in light of predicted increases in climate change-induced storm frequency. These results point to a potential conservation strategy that includes coastal management for adapting to climate change-induced mismatch of migrations. ?? 2011 The Authors. Animal Conservation ?? 2011 The Zoological Society of London.

  15. Mitigating the effects of higher order multipole fields in the magnets of the Accelerator Test Facility 2 at KEK

    Institute of Scientific and Technical Information of China (English)

    BAI Sha; P. Bambade; WANG Dou; GAO Jie; M. Woodley; M. Masuzawa


    The ATF2 project is the final focus system prototype for the ILC and CLIC linear collider projects,with the purpose of reaching a 37nm vertical beam size at the interaction point.In the nanometer beam size regime,higher order multipoles in magnets become a crucial point for consideration.The strength and rotation angle of the ATF2 QEA magnets were reconstructed from the IHEP measurements and compared with the KEK ones to be identical.Based on the study of the skew multipoles sensitivity,we report on the analysis of the possible mitigation of the measured multipoles.A suggestion is given which will benefit the ATF2 present commissioning to reach the goal beam size,and also the reduced β optics in future.

  16. Mitigation analysis for Estonia

    Energy Technology Data Exchange (ETDEWEB)

    Martins, A.; Roos, J.; Pesur, A. [Inst. of Energy Research, Tallinn (Estonia)] [and others


    The present report provides data on the mitigation analysis of Estonia. The results for energy, forest and agricultural sectors and macro-economic analysis are given. The Government of Estonia has identified the development of energy production as the main strategical means in the movement towards market economy. Now 99% of electricity generation and about 25% of heat production in Estonia is based on oil shale combustion. To increase the efficiency of oil shale-fired power plants and decrease CO{sub 2} emissions, the State Enterprise (SE) Eesti Energia (Estonian Energy) is planning to reconstruct these power plants and introduce the Circulating Fluidized Bed (CFB) combustion technology for oil shale burning to replace the Pulverized Combustion (PC). According to the Estonian Forest Policy, two general objectives are of importance: sustainability in forestry and efficiency in forest management. For the reduction of greenhouse gases (GHG) emissions from agriculture, it is necessary to increase the efficiency of production resource usage. The growth of the GDP in 1995 was 2.9% as a result of large-scale privatization activities in Estonia and re-introduction of the available, but unused production capacities with the help of foreign and domestic investments. It is assumed that the medium growth rate of GDP reaches 6% in 1998.

  17. 12 CFR 702.108 - Risk mitigation credit. (United States)


    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective...

  18. Effects of three methane mitigation agents on parameters of kinetics of total and hydrogen gas production, ruminal fermentation and hydrogen balance using in vitro technique. (United States)

    Wang, Min; Wang, Rong; Yang, Shan; Deng, Jin Ping; Tang, Shao Xun; Tan, Zhi Liang


    Methane (CH4 ) can be mitigated through directly inhibiting methanogen activity and starving methanogens by hydrogen (H2 ) sink. Three types of mechanism (i.e. bromoethanesulphonate (BES), nitrate and emodin) and doses of CH4 mitigation agents were employed to investigate their pathways of CH4 inhibition. Results indicated that both BES and emodin inhibited CH4 production and altered H2 balance, which could be accompanied by decreased dry matter disappearance (DMD), fractional rate of gH2 formation, volatile fatty acid (VFA) production, ability to produce and use reducing equivalences and molecular H2 , and increased final asymptotic gH2 production, time to the peak of gH2 , discrete lag time of gH2 production and fermentation efficiency. However, emodin decreased gas volume produced by rapidly fermentable components of substrate and the rate of fermentation at early stage of incubation, while BES supplementation inhibited gas volume produced by both rapidly and slowly fermentable components of substrate and the rate of fermentation at middle or late stage of incubation. The nitrate supplementation inhibited CH4 production without affecting VFA profile, because of its dual role as H2 sink and being toxic to methanogens. Nitrate supplementation had more complicated pattern of fermentation, VFA production and profile and H2 balance in comparison to BES and emodin supplementation.

  19. Albeni Falls Wildlife Mitigation Project, 2008 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Soults, Scott [Kootenai Tribe of Idaho


    The Albeni Falls Interagency Work Group (AFIWG) was actively involved in implementing wildlife mitigation activities in late 2007, but due to internal conflicts, the AFIWG members has fractionated into a smaller group. Implementation of the monitoring and evaluation program continued across protected lands. As of 2008, The Albeni Falls Interagency Work Group (Work Group) is a coalition comprised of wildlife managers from three tribal entities (Kalispel Tribe, Kootenai Tribe, Coeur d Alene Tribe) and the US Army Corps of Engineers. The Work Group directs where wildlife mitigation implementation occurs in the Kootenai, Pend Oreille and Coeur d Alene subbasins. The Work Group is unique in the Columbia Basin. The Columbia Basin Fish and Wildlife Authority (CBFWA) wildlife managers in 1995, approved what was one of the first two project proposals to implement mitigation on a programmatic basis. The maintenance of this kind of approach through time has allowed the Work Group to implement an effective and responsive habitat protection program by reducing administrative costs associated with site-specific project proposals. The core mitigation entities maintain approximately 9,335 acres of wetland/riparian habitats in 2008.

  20. OEM Emergency Prevention and Mitigation Information (United States)

    U.S. Environmental Protection Agency — The Office of Emergency Management maintains information relevant to preventing emergencies before they occur, and/or mitigating the effects of emergency when they...

  1. From fatalism to mitigation: A conceptual framework for mitigating fetal programming of chronic disease by maternal obesity. (United States)

    Boone-Heinonen, Janne; Messer, Lynne C; Fortmann, Stephen P; Wallack, Lawrence; Thornburg, Kent L


    Prenatal development is recognized as a critical period in the etiology of obesity and cardiometabolic disease. Potential strategies to reduce maternal obesity-induced risk later in life have been largely overlooked. In this paper, we first propose a conceptual framework for the role of public health and preventive medicine in mitigating the effects of fetal programming. Second, we review a small but growing body of research (through August 2015) that examines interactive effects of maternal obesity and two public health foci - diet and physical activity - in the offspring. Results of the review support the hypothesis that diet and physical activity after early life can attenuate disease susceptibility induced by maternal obesity, but human evidence is scant. Based on the review, we identify major gaps relevant for prevention research, such as characterizing the type and dose response of dietary and physical activity exposures that modify the adverse effects of maternal obesity in the offspring. Third, we discuss potential implications of interactions between maternal obesity and postnatal dietary and physical activity exposures for interventions to mitigate maternal obesity-induced risk among children. Our conceptual framework, evidence review, and future research directions offer a platform to develop, test, and implement fetal programming mitigation strategies for the current and future generations of children.

  2. Clickers don't always help: Classroom context and goals can mitigate clicker effects on student learning (United States)

    Shapiro, Amy; O'Rielly, Grant; Sims-Knight, Judith


    Clickers are commonly used in large-enrollment introductory courses in order to encourage attendance, increase student engagement and improve learning. We report the results from a highly controlled study of factual and conceptual clicker questions in calculus-based introductory physics courses, on students' performance on the factual and conceptual exam questions they targeted. We found that clicker questions did not enhance student performance on either type of exam question. The use of factual clicker questions actually decreased student performance on conceptual exam questions, however. Directing students' attention to surface features of the course content may distract them from the important underlying concepts. The conceptual clicker questions were likely ineffective because the practice students got on homework questions had a stronger effect than the single question posed in class. Interestingly, the same studies in general education biology and psychology courses show a strong, positive effect of clickers on student learning. This study suggest that the usefulness of clickers should be weighed in the context of other course activities and goals. Secondary analyses will explore the effect of students' GPA, motivation and study strategies on the results. This work was supported by the Institute of Education Sciences, US Dept. of Education, through Grant R305A100625 to UMass Dartmouth. The opinions expressed are those of the authors and do not represent views of the Institute or the US Dept. of Education.


    Directory of Open Access Journals (Sweden)

    A. N. Barkovskiy


    Full Text Available The article presents major results of the work performed by St. Petersburg Research Institute of Radiation Hygiene after Professor P. V. Ramzaev on public contracts signed within the implementation of the Federal targeted program “ Mitigation of the radiation accidents’ consequences for the period until 2015” ( Direction IV “ Streamlining of monitoring systems and their elements and situation forecasting on radioactively contaminated territories paragraph 14 “The analyses and comprehensive evaluation of radiation situation changes on radioactively contaminated territories “ aimed at compilation of radioactively contaminated zones’ settlements list and Direction VI “Awareness raising and social -psychological rehabilitation of radiation- affected residents”, paragraph 20 “Creation of unified informational system on ensuring population’s radiation safety and overcoming radiation accidents’ consequences via development of the federal and regional informational resources’ systems” and “ Joint activities program on mitigation of the Chernobyl disaster within the Union State for the period until 2016” ( Direction II “ Streamlining of unified radiation protection system in radioactively contaminated territories” paragraph 2.1 “ The harmonization of requirements, methods and technologies aimed at mitigation of Russian and Belorussian population’s internal and external exposure, the development of radiation control and monitoring unified system”, sub-paragraph 2.1.1 “The development of unified assessment and forecast system for population exposure doses and rationing of radionuclide – containing foodstuffs, agricultural products and forest preserves based on the international approaches” over the period from 2011 to 2015.

  4. Managing multiple diffuse pressures on water quality and ecological habitat: Spatially targeting effective mitigation actions at the landscape scale. (United States)

    Joyce, Hannah; Reaney, Sim


    Catchment systems provide multiple benefits for society, including: land for agriculture, climate regulation and recreational space. Yet, these systems also have undesirable externalities, such as flooding, and the benefits they create can be compromised through societal use. For example, agriculture, forestry and urban land use practices can increase the export of fine sediment and faecal indicator organisms (FIO) delivered to river systems. These diffuse landscape pressures are coupled with pressures on the in stream temperature environment from projected climate change. Such pressures can have detrimental impacts on water quality and ecological habitat and consequently the benefits they provide for society. These diffuse and in-stream pressures can be reduced through actions at the landscape scale but are commonly tackled individually. Any intervention may have benefits for other pressures and hence the challenge is to consider all of the different pressures simultaneously to find solutions with high levels of cross-pressure benefits. This research presents (1) a simple but spatially distributed model to predict the pattern of multiple pressures at the landscape scale, and (2) a method for spatially targeting the optimum location for riparian woodland planting as mitigation action against these pressures. The model follows a minimal information requirement approach along the lines of SCIMAP ( This approach defines the critical source areas of fine sediment diffuse pollution, rapid overland flow and FIOs, based on the analysis of the pattern of the pressure in the landscape and the connectivity from source areas to rivers. River temperature was modeled using a simple energy balance equation; focusing on temperature of inflowing and outflowing water across a catchment. The model has been calibrated using a long term observed temperature record. The modelling outcomes enabled the identification of the severity of each pressure in relative rather

  5. The effectiveness of unitization in mitigating age-related relational learning impairments depends on existing cognitive status. (United States)

    D'Angelo, Maria C; Smith, Victoria M; Kacollja, Arber; Zhang, Felicia; Binns, Malcolm A; Barense, Morgan D; Ryan, Jennifer D


    Binding relations among items in the transverse patterning (TP) task is dependent on the integrity of the hippocampus and its extended network. Older adults have impaired TP learning, corresponding to age-related reductions in hippocampal volumes. Unitization is a training strategy that can mitigate TP impairments in amnesia by reducing reliance on hippocampal-dependent relational binding and increasing reliance on fused representations. Here we examined whether healthy older adults and those showing early signs of cognitive decline would also benefit from unitization. Although both groups of older adults had neuropsychological performance within the healthy range, their TP learning differed both under standard and unitized training conditions. Healthy older adults with impaired TP learning under standard training benefited from unitized training. Older adults who failed the Montreal Cognitive Assessment (MoCA) showed greater impairments under standard conditions, and showed no evidence of improvement with unitization. These individuals' failures to benefit from unitization may be a consequence of early deficits not seen in older adults who pass the MoCA.

  6. The impact of arbuscular mycorrhizal fungi in mitigating salt-induced adverse effects in sweet basil (Ocimum basilicum L.

    Directory of Open Access Journals (Sweden)

    Khalid M. Elhindi


    Full Text Available Salinity is one of the serious abiotic stresses adversely affecting the majority of arable lands worldwide, limiting the crop productivity of most of the economically important crops. Sweet basil (Osmium basilicum plants were grown in a non-saline soil (EC = 0.64 dS m−1, in low saline soil (EC = 5 dS m−1, and in a high saline soil (EC = 10 dS m−1. There were differences between arbuscular mycorrhizal (Glomus deserticola colonized plants (+AMF and non-colonized plants (−AMF. Mycorrhiza mitigated the reduction of K, P and Ca uptake due to salinity. The balance between K/Na and between Ca/Na was improved in +AMF plants. Growth enhancement by mycorrhiza was independent from plant phosphorus content under high salinity levels. Different growth parameters, salt stress tolerance and accumulation of proline content were investigated, these results showed that the use of mycorrhizal inoculum (AMF was able to enhance the productivity of sweet basil plants under salinity conditions. Mycorrhizal inoculation significantly increased chlorophyll content and water use efficiency under salinity stress. The sweet basil plants appeared to have high dependency on AMF which improved plant growth, photosynthetic efficiency, gas exchange and water use efficiency under salinity stress. In this study, there was evidence that colonization with AMF can alleviate the detrimental salinity stress influence on the growth and productivity of sweet basil plants.

  7. Possibilities for carbon sequestration in Irish forests. COST E21 Workshop. Contribution of forests and forestry to mitigate greenhouse effects. Joensuu (Finland. 28-30 Sep 2000

    Directory of Open Access Journals (Sweden)

    Byrne K.A.


    Full Text Available Ireland has a rapidly expanding forest estate which covers some 9/ of the land area. It is government policy to increase this to 17/ by the year 2030. Preliminary studies suggest that forestry activities have the potential to contribute significantly to the mitigation of greenhouse gas emissions. Although some studies have been carried out the determination of the carbon stores and sinks in Irish forests will require a considerable research effort in the future. A key aspect of such studies will be field based studies which measure all components of the carbon cycle and their relationship to climatic and environmental conditions as well as management practices. Many of these issues will be addressed in the recently announced research programme of the Council for Forest Research and Development (COFORD.

  8. Environmental Satellites: Planning Required to Mitigate Near-Term Risks and Ensure Long-Term Continuity (United States)


    work together. For example, climate measurements have allowed scientists to better understand the effect of deforestation on how the earth absorbs...development activities. Until the transition risks are effectively mitigated, and unless components are able to continue scheduled development, it...observations such as greenhouse gas levels (e.g., carbon dioxide), aerosol and dust particles, and moisture concentration. When these data are

  9. Contribution of neuroinflammation and immunity to brain aging and the mitigating effects of physical and cognitive interventions. (United States)

    Di Benedetto, Svetlana; Müller, Ludmila; Wenger, Elisabeth; Düzel, Sandra; Pawelec, Graham


    It is widely accepted that the brain and the immune system continuously interact during normal as well as pathological functioning. Human aging is commonly accompanied by low-grade inflammation in both the immune and central nervous systems, thought to contribute to many age-related diseases. This review of the current literature focuses first on the normal neuroimmune interactions occurring in the brain, which promote learning, memory and neuroplasticity. Further, we discuss the protective and dynamic role of barriers to neuroimmune interactions, which have become clearer with the recent discovery of the meningeal lymphatic system. Next, we consider age-related changes of the immune system and possible deleterious influences of immunosenescence and low-grade inflammation (inflammaging) on neurodegenerative processes in the normally aging brain. We survey the major immunomodulators and neuroregulators in the aging brain and their highly tuned dynamic and reciprocal interactions. Finally, we consider our current understanding of how physical activity, as well as a combination of physical and cognitive interventions, may mediate anti-inflammatory effects and thus positively impact brain aging.

  10. IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects. (United States)

    Liu, Y; Wu, Y; Wang, Y; Cai, Y; Hu, B; Bao, G; Fang, H; Zhao, L; Ma, S; Cheng, Q; Song, Y; Liu, Y; Zhu, Z; Chang, H; Yu, X; Sun, A; Zhang, Y; Vignali, D A A; Wu, D; Liu, H


    IL-35 is a newly discovered inhibitory cytokine secreted by regulatory T cells (Tregs) and may have therapeutic potential in several inflammatory disorders. Acute graft-versus-host disease (aGVHD) is a major complication of allogeneic hematopoietic stem cell transplantation and caused by donor T cells and inflammatory cytokines. The role of IL-35 in aGVHD is still unknown. Here we demonstrate that IL-35 overexpression suppresses CD4(+) effector T-cell activation, leading to a reduction in alloreactive T-cell responses and aGVHD severity. It also leads to the expansion of CD4(+)Foxp3(+) Tregs in the aGVHD target organs. Furthermore, IL-35 overexpression results in a selective decrease in the frequency of Th1 cells and an increase of IL-10-producing CD4(+) T cells in aGVHD target tissues. Serum levels of TNF-α, IFN-γ, IL-6, IL-22 and IL-23 decrease and IL-10 increases in response to IL-35. Most importantly, IL-35 preserves graft-versus-leukemia effect. Finally, aGVHD grade 2-4 patients have decreased serum IL-35 levels comparing with time-matched patients with aGVHD grade 0-1. Our findings indicate that IL-35 has an important role in reducing aGVHD through promoting the expansion of Tregs and repressing Th1 responses, and should be investigated as the therapeutic strategy for aGVHD.

  11. Statistical Analysis of the Effectiveness of Seawalls and Coastal Forests in Mitigating Tsunami Impacts in Iwate and Miyagi Prefectures. (United States)

    Nateghi, Roshanak; Bricker, Jeremy D; Guikema, Seth D; Bessho, Akane


    The Pacific coast of the Tohoku region of Japan experiences repeated tsunamis, with the most recent events having occurred in 1896, 1933, 1960, and 2011. These events have caused large loss of life and damage throughout the coastal region. There is uncertainty about the degree to which seawalls reduce deaths and building damage during tsunamis in Japan. On the one hand they provide physical protection against tsunamis as long as they are not overtopped and do not fail. On the other hand, the presence of a seawall may induce a false sense of security, encouraging additional development behind the seawall and reducing evacuation rates during an event. We analyze municipality-level and sub-municipality-level data on the impacts of the 1896, 1933, 1960, and 2011 tsunamis, finding that seawalls larger than 5 m in height generally have served a protective role in these past events, reducing both death rates and the damage rates of residential buildings. However, seawalls smaller than 5 m in height appear to have encouraged development in vulnerable areas and exacerbated damage. We also find that the extent of flooding is a critical factor in estimating both death rates and building damage rates, suggesting that additional measures, such as multiple lines of defense and elevating topography, may have significant benefits in reducing the impacts of tsunamis. Moreover, the area of coastal forests was found to be inversely related to death and destruction rates, indicating that forests either mitigated the impacts of these tsunamis, or displaced development that would otherwise have been damaged.

  12. Endogenous mitigation of H2S inside of the landfills. (United States)

    Fang, Yuan; Zhong, Zhong; Shen, Dongsheng; Du, Yao; Xu, Jing; Long, Yuyang


    Vast quantities of hydrogen sulfide (H2S) emitted from landfill sites require urgent disposal. The current study focused on source control and examined the migration and conversion behavior of sulfur compounds in two lab-scale simulated landfills with different operation modes. It aimed to explore the possible strategies and mechanisms for H2S endogenous mitigation inside of landfills during decomposition. It was found that the strength of H2S emissions from the landfill sites was dependent on the municipal solid waste (MSW) degradation speed and vertical distribution of sulfide. Leachate recirculation can shorten both the H2S influence period and pollution risk to the surrounding environment. H2S endogenous mitigation may be achieved by chemical oxidation, biological oxidation, adsorption, and/or precipitation in different stages. Migration and conversion mainly affected H2S release behavior during the initial stabilization phase in the landfill. Microbial activities related to sulfur, nitrogen, and iron can further promote H2S endogenous mitigation during the high reducing phase. Thus, H2S endogenous mitigation can be effectively enhanced via control of the aforementioned processes.

  13. A web-based tool for ranking landslide mitigation measures (United States)

    Lacasse, S.; Vaciago, G.; Choi, Y. J.; Kalsnes, B.


    As part of the research done in the European project SafeLand "Living with landslide risk in Europe: Assessment, effects of global change, and risk management strategies", a compendium of structural and non-structural mitigation measures for different landslide types in Europe was prepared, and the measures were assembled into a web-based "toolbox". Emphasis was placed on providing a rational and flexible framework applicable to existing and future mitigation measures. The purpose of web-based toolbox is to assist decision-making and to guide the user in the choice of the most appropriate mitigation measures. The mitigation measures were classified into three categories, describing whether the mitigation measures addressed the landslide hazard, the vulnerability or the elements at risk themselves. The measures considered include structural measures reducing hazard and non-structural mitigation measures, reducing either the hazard or the consequences (or vulnerability and exposure of elements at risk). The structural measures include surface protection and control of surface erosion; measures modifying the slope geometry and/or mass distribution; measures modifying surface water regime - surface drainage; measures mo¬difying groundwater regime - deep drainage; measured modifying the mechanical charac¬teristics of unstable mass; transfer of loads to more competent strata; retaining structures (to modify slope geometry and/or to transfer stress to compe¬tent layer); deviating the path of landslide debris; dissipating the energy of debris flows; and arresting and containing landslide debris or rock fall. The non-structural mitigation measures, reducing either the hazard or the consequences: early warning systems; restricting or discouraging construction activities; increasing resistance or coping capacity of elements at risk; relocation of elements at risk; sharing of risk through insurance. The measures are described in the toolbox with fact sheets providing a

  14. JIT Spraying and Mitigations

    CERN Document Server

    Bania, Piotr


    With the discovery of new exploit techniques, novel protection mechanisms are needed as well. Mitigations like DEP (Data Execution Prevention) or ASLR (Address Space Layout Randomization) created a significantly more difficult environment for exploitation. Attackers, however, have recently researched new exploitation methods which are capable of bypassing the operating system’s memory mitigations. One of the newest and most popular exploitation techniques to bypass both of the aforementioned security protections is JIT memory spraying, introduced by Dion Blazakis. In this article we will present a short overview of the JIT spraying technique and also novel mitigation methods against this innovative class of attacks. An anti-JIT spraying library was created as part of our shellcode execution prevention system.

  15. The potential effects of antioxidant feed additives in mitigating the adverse effects of corn naturally contaminated with Fusarium mycotoxins on antioxidant systems in the intestinal mucosa, plasma, and liver in weaned pigs. (United States)

    Van Le Thanh, Bich; Lemay, Michel; Bastien, Alexandre; Lapointe, Jérôme; Lessard, Martin; Chorfi, Younès; Guay, Frédéric


    Seventy-two piglets (6.0 kg BW) were randomly distributed within six different dietary treatments to evaluate the effect of deoxynivalenol (DON) and the potential of four antioxidant feed additives in mitigating the adverse effects of DON on growth performances and oxidative status. Dietary treatments were as follows: control diet 0.8 mg/kg DON; contaminated diet (DON-contaminated diet) 3.1 mg/kg DON; and four contaminated diets, each supplemented with a different antioxidant feed additive, DON + vitamins, DON + organic selenium (Se)/glutathione (GSH), DON + quercetin, and DON + COMB (vitamins + Se/GSH + quercetin from the other treatments). Although DON was the main mycotoxin in the contaminated diet, this diet also contained 1.8 mg/kg of zearalenone (ZEN). The "mycotoxin" effects therefore included the combined effect of these two mycotoxins, DON, and ZEN. The DON-ZEN ingestion did not affect growth performances, average daily gain (ADG), average daily feed intake (ADFI), and feed efficiency (G:F ratio), but partially induced oxidative stress in weaned pigs as shown by increased malondialdehyde (MDA) content in the plasma and superoxide dismutase (SOD) activity in liver (P  0.05). Supplementation with individual antioxidant feed additive had a limited effect in weaned pigs fed DON-ZEN-contaminated diets. Combination of antioxidants (vitamins A, C, and E, quercetin, and organic Se/GSH) reduced plasma and liver MDA content and SOD activity in liver (P < 0.05) of piglets fed DON-ZEN-contaminated diets. Furthermore, this combination also reduced MDA content in the ileum (P < 0.05), although activity of glutathione peroxidases (GPx), SOD or catalase (CAT) in the ileum was not affected by DON-ZEN contamination or antioxidant supplements. In conclusion, DON-ZEN contamination induced oxidative stress in weaned pigs and combination of antioxidant feed additives restored partially the oxidative status. Further studies will be necessary to assess whether the

  16. Rural methods to mitigate arsenic contaminated water


    Parajuli, Krishna


    Consumption of arsenic contaminated water is one of the burning issues in the rural world. Poor public awareness program about health effects of drinking arsenic contaminated water and the rural methods to mitigate this problem poses a great threat of arsenic poisoning many people of the rural world. In this thesis, arsenic removal efficiency and the working mechanism of four rural and economical arsenic mitigation technologies i.e. solar oxidation and reduction of arsenic (SORAS), Bucket tr...

  17. A conceptual framework for hydropeaking mitigation. (United States)

    Bruder, Andreas; Tonolla, Diego; Schweizer, Steffen P; Vollenweider, Stefan; Langhans, Simone D; Wüest, Alfred


    Hydropower plants are an important source of renewable energy. In the near future, high-head storage hydropower plants will gain further importance as a key element of large-scale electricity production systems. However, these power plants can cause hydropeaking which is characterized by intense unnatural discharge fluctuations in downstream river reaches. Consequences on environmental conditions in these sections are diverse and include changes to the hydrology, hydraulics and sediment regime on very short time scales. These altered conditions affect river ecosystems and biota, for instance due to drift and stranding of fishes and invertebrates. Several structural and operational measures exist to mitigate hydropeaking and the adverse effects on ecosystems, but estimating and predicting their ecological benefit remains challenging. We developed a conceptual framework to support the ecological evaluation of hydropeaking mitigation measures based on current mitigation projects in Switzerland and the scientific literature. We refined this framework with an international panel of hydropeaking experts. The framework is based on a set of indicators, which covers all hydrological phases of hydropeaking and the most important affected abiotic and biotic processes. Effects of mitigation measures on these indicators can be predicted quantitatively using prediction tools such as discharge scenarios and numerical habitat models. Our framework allows a comparison of hydropeaking effects among alternative mitigation measures, to the pre-mitigation situation, and to reference river sections. We further identified key issues that should be addressed to increase the efficiency of current and future projects. They include the spatial and temporal context of mitigation projects, the interactions of river morphology with hydropeaking effects, and the role of appropriate monitoring to evaluate the success of mitigation projects.

  18. Defeating the Active Shooter: Applying Facility Upgrades in Order to Mitigate the Effects of Active Shooters in High Occupancy Facilities (United States)


    infrastructure, at our borders, ports, and airports, and to enhance overall air, maritime, transportation, and space and cyber security.53...Climates which addresses this problem and makes useful suggestions for preventing school violence. First, a culture of safety in which bullying and...from Cho, who had previously stabbed the carpet in her room with a knife and was currently sending harassing instant messages and Facebook posts to

  19. Pedestrian injury mitigation by autonomous braking. (United States)

    Rosén, Erik; Källhammer, Jan-Erik; Eriksson, Dick; Nentwich, Matthias; Fredriksson, Rikard; Smith, Kip


    The objective of this study was to calculate the potential effectiveness of a pedestrian injury mitigation system that autonomously brakes the car prior to impact. The effectiveness was measured by the reduction of fatally and severely injured pedestrians. The database from the German In-Depth Accident Study (GIDAS) was queried for pedestrians hit by the front of cars from 1999 to 2007. Case by case information on vehicle and pedestrian velocities and trajectories were analysed to estimate the field of view needed for a vehicle-based sensor to detect the pedestrians one second prior to the crash. The pre-impact braking system was assumed to activate the brakes one second prior to crash and to provide a braking deceleration up to the limit of the road surface conditions, but never to exceed 0.6 g. New impact speeds were then calculated for pedestrians that would have been detected by the sensor. These calculations assumed that all pedestrians who were within a given field of view but not obstructed by surrounding objects would be detected. The changes in fatality and severe injury risks were quantified using risk curves derived by logistic regression of the accident data. Summing the risks for all pedestrians, relationships between mitigation effectiveness, sensor field of view, braking initiation time, and deceleration were established. The study documents that the effectiveness at reducing fatally (severely) injured pedestrians in frontal collisions with cars reached 40% (27%) at a field of view of 40 degrees. Increasing the field of view further led to only marginal improvements in effectiveness.

  20. Space Debris Mitigation Guidelines (United States)

    Johnson, Nicholas L.


    The purpose of national and international space debris mitigation guides is to promote the preservation of near-Earth space for applications and exploration missions far into the future. To accomplish this objective, the accumulation of objects, particularly in long-lived orbits, must be eliminated or curtailed.

  1. Mitigating the Stress of Drought on Soil Respiration by Selective Thinning: Contrasting Effects of Drought on Soil Respiration of Two Oak Species in a Mediterranean Forest

    Directory of Open Access Journals (Sweden)

    Chao-Ting Chang


    Full Text Available Drought has been shown to reduce soil respiration (SR in previous studies. Meanwhile, studies of the effect of forest management on SR yielded contrasting results. However, little is known about the combined effect of drought and forest management on SR. To investigate if the drought stress on SR can be mitigated by thinning, we implemented plots of selective thinning and 15% reduced rainfall in a mixed forest consisting of the evergreen Quercus ilex and deciduous Quercus cerrioides; we measured SR seasonally from 2004 to 2007. Our results showed a clear soil moisture threshold of 9%; above this value, SR was strongly dependent on soil temperature, with Q10 of 3.0–3.8. Below this threshold, the relationship between SR and soil temperature weakened. We observed contrasting responses of SR of target oak species to drought and thinning. Reduced rainfall had a strong negative impact on SR of Q. cerrioides, whereas the effect on SR for Q. ilex was marginal or even positive. Meanwhile, selective thinning increased SR of Q. cerrioides, but reduced that of Q. ilex. Overall, our results showed that the negative effect of drought on SR can be offset through selective thinning, but the effect is attenuated with time.

  2. Flicker Mitigation by Individual Pitch Control of Variable Speed Wind Turbines With DFIG

    DEFF Research Database (Denmark)

    Zhang, Yunqian; Chen, Zhe; Hu, Weihao;


    generatorto investigate the flicker emission and mitigation issues. An individual pitch control (IPC) strategy is proposed to reduce the flicker emission at different wind speed conditions. The IPC scheme is proposed and the individual pitch controller is designed according to the generator active power...... and the azimuth angle of the wind turbine. The simulations are performed on the NREL (National Renewable Energy Laboratory) 1.5-MW upwind reference wind turbine model. Simulation results show that damping the generator active power by IPC is an effective means for flicker mitigation of variable speed wind...

  3. Mitigating effects of ex situ application of rice straw on CH4 and N2O emissions from paddy-upland coexisting system (United States)

    Wang, Wei; Wu, Xiaohong; Chen, Anlei; Xie, Xiaoli; Wang, Yunqiu; Yin, Chunmei


    The in situ application of rice straw enhances CH4 emissions by a large margin. The ex situ application of rice straw in uplands, however, may mitigate total global warming potential (GWP) of CH4 and N2O emissions from paddy-upland coexisting systems. To evaluate the efficiency of this practice, two field trials were conducted in rice-rice-fallow and maize-rape cropping systems, respectively. Year-round measurements of CH4 and N2O emissions were conducted to evaluate the system-scaled GWP. The results showed that CH4 accounted for more than 98% of GWP in paddy. Straw removal from paddy decreased 44.7% (302.1 kg ha‑1 yr‑1) of CH4 emissions and 51.2% (0.31 kg ha‑1 yr‑1) of N2O emissions, thus decreased 44.8% (7693 kg CO2-eqv ha‑1 yr‑1) of annual GWP. N2O accounted for almost 100% of GWP in upland. Straw application in upland had insignificant effects on CH4 and N2O emissions, which increased GWP only by 91 kg CO2-eqv ha‑1 yr‑1. So, the transfer of straw from paddy to upland could decrease GWP by 7602 kg CO2-eqv ha‑1 yr‑1. Moreover, straw retention during late rice season contributed to 88.2% of annual GWP increment. It is recommended to transfer early rice straw to upland considering GWP mitigation, nutrient recycling and labor cost.

  4. Anxiogenic effects of developmental bisphenol A exposure are associated with gene expression changes in the juvenile rat amygdala and mitigated by soy.

    Directory of Open Access Journals (Sweden)

    Heather B Patisaul

    Full Text Available Early life exposure to Bisphenol A (BPA, a component of polycarbonate plastics and epoxy resins, alters sociosexual behavior in numerous species including humans. The present study focused on the ontogeny of these behavioral effects beginning in adolescence and assessed the underlying molecular changes in the amygdala. We also explored the mitigating potential of a soy-rich diet on these endpoints. Wistar rats were exposed to BPA via drinking water (1 mg/L from gestation through puberty, and reared on a soy-based or soy-free diet. A group exposed to ethinyl estradiol (50 µg/L and a soy-free diet was used as a positive estrogenic control. Animals were tested as juveniles or adults for anxiety-like and exploratory behavior. Assessment of serum BPA and genistein (GEN, a soy phytoestrogen, confirmed that internal dose was within a human-relevant range. BPA induced anxiogenic behavior in juveniles and loss of sexual dimorphisms in adult exploratory behavior, but only in the animals reared on the soy-free diet. Expression analysis revealed a suite of genes, including a subset known to mediate sociosexual behavior, associated with BPA-induced juvenile anxiety. Notably, expression of estrogen receptor beta (Esr2 and two melanocortin receptors (Mc3r, Mc4r were downregulated. Collectively, these results show that behavioral impacts of BPA can manifest during adolescence, but wane in adulthood, and may be mitigated by diet. These data also reveal that, because ERβ and melanocortin receptors are crucial to their function, oxytocin/vasopressin signaling pathways, which have previously been linked to human affective disorders, may underlie these behavioral outcomes.

  5. Green and cool roofs to mitigate urban heat island effects in the Chicago metropolitan area: evaluation with a regional climate model (United States)

    Sharma, A.; Conry, P.; Fernando, H. J. S.; Hamlet, Alan F.; Hellmann, J. J.; Chen, F.


    The effects of urban heat islands (UHIs) have a substantial bearing on the sustainability of cities and environs. This paper examines the efficacy of green and cool roofs as potential UHI mitigation strategies to make cities more resilient against UHI. We have employed the urbanized version of the Weather Research and Forecasting (uWRF) model at high (1 km) resolution with physically-based rooftop parameterization schemes (conventional, green and cool), a first-time application to the Chicago metropolitan area. We simulated a hot summer period (16-18 August 2013) and assessed (i) UHI reductions for different urban landuse with green/cool roofs, (ii) the interaction of lake breeze and UHI, and (iii) diurnal boundary layer dynamics. The performance of uWRF was evaluated using sensible heat flux and air temperature measurements from an urban mini-field campaign. The simulated roof surface energy balance captured the energy distribution with respective rooftop algorithms. Results showed that daytime roof temperature reduced and varied linearly with increasing green roof fractions, from less than 1 °C for the case of 25% green roof to ˜3 °C during peak daytime for 100% green roof. Diurnal transitions from land to lake breeze and vice versa had a substantial impact on the daytime cycle of roof surface UHI, which had a 3-4 hour lag in comparison to 2 m UHI. Green and cool roofs reduced horizontal and vertical wind speeds and affected lower atmosphere dynamics, including reduced vertical mixing, lower boundary layer depth, and weaker convective rolls. The lowered wind speeds and vertical mixing during daytime led to stagnation of air near the surface, potentially causing air quality issues. The selection of green and cool roofs for UHI mitigation should therefore carefully consider the competing feedbacks. The new results for regional land-lake circulations and boundary layer dynamics from this study may be extended to other urbanized areas, particularly to coastal

  6. Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases. (United States)

    Knutson, Mitchell D; Leeuwenburgh, Christiaan


    Studies show that the plant polyphenol resveratrol can extend the life span of yeast, worms, flies, and fish. It also mitigates the metabolic dysfunction of mice fed high-fat diets. Resveratrol appears to mediate these effects partly by activating SIRT1, a deacetylase enzyme that regulates the activity of several transcriptional factors and enzymes responsive to nutrient availability. However, few foods contain resveratrol and humans metabolize it extensively, resulting in very low systemic bioavailability. Substantial research effort now focuses on identifying and testing more bioavailable and potent activators of SIRT1 for use as pharmacologic interventions in aging and age-related disorders.

  7. Mitigating the Effects of Xuebijing Injection on Hematopoietic Cell Injury Induced by Total Body Irradiation with γ rays by Decreasing Reactive Oxygen Species Levels

    Directory of Open Access Journals (Sweden)

    Deguan Li


    Full Text Available Hematopoietic injury is the most common side effect of radiotherapy. However, the methods available for the mitigating of radiation injury remain limited. Xuebijing injection (XBJ is a traditional Chinese medicine used to treat sepsis in the clinic. In this study, we investigated the effects of XBJ on the survival rate in mice with hematopoietic injury induced by γ ray ionizing radiation (IR. Mice were intraperitoneally injected with XBJ daily for seven days after total body irradiation (TBI. Our results showed that XBJ (0.4 mL/kg significantly increased 30-day survival rates in mice exposed to 7.5 Gy TBI. This effect may be attributable to improved preservation of white blood cells (WBCs and hematopoietic cells, given that bone marrow (BM cells from XBJ-treated mice produced more granulocyte-macrophage colony forming units (CFU-GM than that in the 2 Gy/TBI group. XBJ also decreased the levels of reactive oxygen species (ROS by increasing glutathione (GSH and superoxide dismutase (SOD levels in serum and attenuated the increased BM cell apoptosis caused by 2 Gy/TBI. In conclusion, these findings suggest that XBJ enhances the survival rate of irradiated mice and attenuates the effects of radiation on hematopoietic injury by decreasing ROS production in BM cells, indicating that XBJ may be a promising therapeutic candidate for reducing hematopoietic radiation injury.

  8. Effectiveness of Agricultural Extension Activities

    Directory of Open Access Journals (Sweden)

    Ali AL-Sharafat


    Full Text Available Problem statement: Jordans agricultural extension service is seriously under-staffed and its effectiveness is consequently compromised. Reservations are being expressed about the performance and capability of the agricultural extension system in Jordan. The performance of this sector has been disappointing and has failed to transfer agricultural technology to the farmers. The main objective of this study is to assess the effectiveness of Jordans agricultural extension services. Approach: The effect of extension services on olive productivity in the study area was investigated. A total number of 60 olive producers were selected to be interviewed for this study. This number was enough to achieve the study objectives. The interviewed producers were distributed almost equally within olive production locations in the study area. The sample obtained through the simple random sampling technique. The two groups had been chosen and distributed randomly into an experimental group (30 farmers; 10 for each source of extension service and control group (30 farmers. The experimental group received extension services and the control group received no extension services. Two interview-cum-structured questionnaires were designed and used to collect information and data for this study. The first instrument was designed for farmers who received extension services and the second from farmers who received no extension services. Another questionnaire was designed for administrators of extension organizations concerned with providing extension services to farmers. To find the differences that may exist between two studied groups, One Way Analysis of Variance (ANOVA, t-test and LSD test via Statistical Package for Social Sciences software (SPSS were used. The average net profit obtained from an area of one dynamo of olive farm was the main item to be considered in determining the effectiveness of agricultural extension activities. Results and Conclusion: The results of

  9. Mitigating seabird bycatch during hauling by pelagic longline vessels.

    Directory of Open Access Journals (Sweden)

    Eric Gilman

    Full Text Available Bycatch in longline fisheries threatens the viability of some seabird populations. The Hawaii longline swordfish fishery reduced seabird captures by an order of magnitude primarily through mitigating bycatch during setting. Now, 75% of captures occur during hauling. We fit observer data to a generalized additive regression model with mixed effects to determine the significance of the effect of various factors on the standardized seabird haul catch rate. Density of albatrosses attending vessels during hauling, leader length and year had largest model effects. The standardized haul catch rate significantly increased with increased albatross density during hauling. The standardized catch rate was significantly higher the longer the leader: shorter leaders place weighted swivels closer to hooks, reducing the likelihood of baited hooks becoming available to surface-scavenging albatrosses. There was a significant linear increasing temporal trend in the standardized catch rate, possibly partly due to an observed increasing temporal trend in the local abundance of albatrosses attending vessels during hauling. Swivel weight, Beaufort scale and season were also significant but smaller model effects. Most (81% haul captures were on branchlines actively being retrieved. Future haul mitigation research should therefore focus on reducing bird access to hooks as crew coil branchlines, including methods identified here of shorter leaders and heavier swivels, and other potentially effective methods, including faster branchline coiling and shielding the area where hooks becomes accessible. The proportion of Laysan albatross (Phoebastria immutabilis captures that occurred during hauling was significantly, 1.6 times, higher than for black-footed albatrosses (P. nigripes, perhaps due to differences in the time of day of foraging and in daytime scavenging competitiveness; mitigating haul bycatch would therefore be a larger benefit to Laysans. Locally, findings

  10. Mitigating seabird bycatch during hauling by pelagic longline vessels. (United States)

    Gilman, Eric; Chaloupka, Milani; Wiedoff, Brett; Willson, Jeremy


    Bycatch in longline fisheries threatens the viability of some seabird populations. The Hawaii longline swordfish fishery reduced seabird captures by an order of magnitude primarily through mitigating bycatch during setting. Now, 75% of captures occur during hauling. We fit observer data to a generalized additive regression model with mixed effects to determine the significance of the effect of various factors on the standardized seabird haul catch rate. Density of albatrosses attending vessels during hauling, leader length and year had largest model effects. The standardized haul catch rate significantly increased with increased albatross density during hauling. The standardized catch rate was significantly higher the longer the leader: shorter leaders place weighted swivels closer to hooks, reducing the likelihood of baited hooks becoming available to surface-scavenging albatrosses. There was a significant linear increasing temporal trend in the standardized catch rate, possibly partly due to an observed increasing temporal trend in the local abundance of albatrosses attending vessels during hauling. Swivel weight, Beaufort scale and season were also significant but smaller model effects. Most (81%) haul captures were on branchlines actively being retrieved. Future haul mitigation research should therefore focus on reducing bird access to hooks as crew coil branchlines, including methods identified here of shorter leaders and heavier swivels, and other potentially effective methods, including faster branchline coiling and shielding the area where hooks becomes accessible. The proportion of Laysan albatross (Phoebastria immutabilis) captures that occurred during hauling was significantly, 1.6 times, higher than for black-footed albatrosses (P. nigripes), perhaps due to differences in the time of day of foraging and in daytime scavenging competitiveness; mitigating haul bycatch would therefore be a larger benefit to Laysans. Locally, findings identify opportunities

  11. Status Review of Wildlife Mitigation at Columbia Basin Hydroelectric Projects, Oregon Facilities, Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Bedrossian, Karen L.


    The report presents a review and documentation of existing information on wildlife resources at Columbia River Basin hydroelectric facilities within Oregon. Effects of hydroelectric development and operation; existing agreements; and past, current and proposed wildlife mitigation, enhancement, and protection activities were considered. (ACR)

  12. Smart disaster mitigation in Thailand (United States)

    Aimmanee, S.; Ekkawatpanit, C.; Asanuma, H.


    Thailand is notoriously exposed to several natural disasters, from heavy thunder storms to earthquakes and tsunamis, since it is located in the tropical area and has tectonic cracks underneath the ground. Besides these hazards flooding, despite being less severe, occurs frequently, stays longer than the other disasters, and affects a large part of the national territory. Recently in 2011 have also been recorded the devastating effects of major flooding causing the economic damages and losses around 50 billion dollars. Since Thailand is particularly exposed to such hazards, research institutions are involved in campaigns about monitoring, prevention and mitigation of the effects of such phenomena, with the aim to secure and protect human lives, and secondly, the remarkable cultural heritage. The present paper will first make a brief excursus on the main Thailand projects aimed at the mitigation of natural disasters, referring to projects of national and international relevance, being implemented, such as the ESCAP1999 (flow regime regulation and water conservation). Adaptable devices such as foldable flood barriers and hydrodynamically supported temporary banks have been utilized when flooding. In the second part of the paper, will be described some new ideas concerning the use of smart and biomimicking column structures capable of high-velocity water interception and velocity detection in the case of tsunami. The pole configuration is composite cylindrical shell structure embedded with piezoceramic sensor. The vortex shedding of the flow around the pole induces the vibration and periodically strains the piezoelectric element, which in turn generates the electrical sensorial signal. The internal space of the shell is filled with elastic foam to enhance the load carrying capability due to hydrodynamic application. This more rigid outer shell inserted with soft core material resemble lotus stem in nature in order to prolong local buckling and ovalization of column

  13. Using periodicity to mitigate ground vibration

    DEFF Research Database (Denmark)

    Andersen, Lars Vabbersgaard


    Introduction of trenches, barriers and wave impeding blocks on the transmission path between a source and receiver can be used for mitigation of ground vibration. However, to be effective a barrier must have a depth of about one wavelength of the waves to be mitigated. Hence, while great reductions...... for wave propagation, effectively reducing the transmission of energy in certain frequency bands known as stop bands or band gaps, thus only allowing propagation in the so-called pass bands. In this paper, a stratified ground with two soil layers is considered and two types of periodicity is analysed...... periodicity. Floquet analysis is then performed in order to quantify the number of propagating wave modes as well as modes with low degrees of attenuation. As a conclusion of the analysis, effective mitigation in the low frequency range can be established. The position of stop bands can be manipulated...

  14. Soft error mechanisms, modeling and mitigation

    CERN Document Server

    Sayil, Selahattin


    This book introduces readers to various radiation soft-error mechanisms such as soft delays, radiation induced clock jitter and pulses, and single event (SE) coupling induced effects. In addition to discussing various radiation hardening techniques for combinational logic, the author also describes new mitigation strategies targeting commercial designs. Coverage includes novel soft error mitigation techniques such as the Dynamic Threshold Technique and Soft Error Filtering based on Transmission gate with varied gate and body bias. The discussion also includes modeling of SE crosstalk noise, delay and speed-up effects. Various mitigation strategies to eliminate SE coupling effects are also introduced. Coverage also includes the reliability of low power energy-efficient designs and the impact of leakage power consumption optimizations on soft error robustness. The author presents an analysis of various power optimization techniques, enabling readers to make design choices that reduce static power consumption an...

  15. Wetland Mitigation Monitoring at the Fernald Preserve - 13200

    Energy Technology Data Exchange (ETDEWEB)

    Powell, Jane [Fernald Preserve Site Manager, DOE Office of Legacy Management, Harrison, Ohio (United States); Bien, Stephanie; Decker, Ashlee; Homer, John [Environmental Scientist, S.M. Stoller Corporation, Harrison, Ohio (United States); Wulker, Brian [Intern, S.M. Stoller Corporation, Harrison, Ohio (United States)


    The U.S. Department of Energy is responsible for 7.2 hectares (17.8 acres) of mitigation wetland at the Fernald Preserve, Ohio. Remedial activities affected the wetlands, and mitigation plans were incorporated into site-wide ecological restoration planning. In 2008, the Fernald Natural Resource Trustees developed a comprehensive wetland mitigation monitoring approach to evaluate whether compensatory mitigation requirements have been met. The Fernald Preserve Wetland Mitigation Monitoring Plan provided a guideline for wetland evaluations. The Ohio Environmental Protection Agency (Ohio EPA) wetland mitigation monitoring protocols were adopted as the means for compensatory wetland evaluation. Design, hydrologic regime, vegetation, wildlife, and biogeochemistry were evaluated from 2009 to 2011. Evaluations showed mixed results when compared to the Ohio EPA performance standards. Results of vegetation monitoring varied, with the best results occurring in wetlands adjacent to forested areas. Amphibians, particularly ambystomatid salamanders, were observed in two areas adjacent to forested areas. Not all wetlands met vegetation performance standards and amphibian biodiversity metrics. However, Fernald mitigation wetlands showed substantially higher ratings compared to other mitigated wetlands in Ohio. Also, soil sampling results remain consistent with other Ohio mitigated wetlands. The performance standards are not intended to be 'pass/fail' criteria; rather, they are reference points for use in making decisions regarding future monitoring and maintenance. The Trustees approved the Fernald Preserve Wetland Mitigation Monitoring Report with the provision that long-term monitoring of the wetlands continues at the Fernald Preserve. (authors)

  16. Effects of Low-Carbon Technologies and End-Use Electrification on Energy-Related Greenhouse Gases Mitigation in China by 2050

    Directory of Open Access Journals (Sweden)

    Zheng Guo


    Full Text Available Greenhouse gas emissions in China have been increasing in line with its energy consumption and economic growth. Major means for energy-related greenhouse gases mitigation in the foreseeable future are transition to less carbon intensive energy supplies and structural changes in energy consumption. In this paper, a bottom-up model is built to examine typical projected scenarios for energy supply and demand, with which trends of energy-related carbon dioxide emissions by 2050 can be analyzed. Results show that low-carbon technologies remain essential contributors to reducing emissions and altering emissions trends up to 2050. By pushing the limit of current practicality, emissions reduction can reach 20 to 28 percent and the advent of carbon peaking could shift from 2040 to 2030. In addition, the effect of electrification at end-use sectors is studied. Results show that electrifying transport could reduce emissions and bring the advent of carbon peaking forward, but the effect is less significant compared with low-carbon technologies. Moreover, it implies the importance of decarbonizing power supply before electrifying end-use sectors.

  17. Using fuzzy logic to mitigate the effect of multiple-sclerosis tremors on a wheelchair joystick controller

    NARCIS (Netherlands)

    Corbett, Dan; Zwaag, van der Berend Jan; Antoniou, Grigoris; Slaney, John


    We have designed a fuzzy logic wheelchair controller to minimise the effect of Multiple Sclerosis hand tremors on a wheelchair joystick controller. The aim is to give people with Multiple Sclerosis better control of an electric wheelchair by removing tremors from the joystick signal. This has been a

  18. Stand by Me: The Effects of Peer and Teacher Support in Mitigating the Impact of Bullying on Quality of Life (United States)

    Flaspohler, Paul D.; Elfstrom, Jennifer L.; Vanderzee, Karin L.; Sink, Holli E.; Birchmeier, Zachary


    Bullying is one of the most common forms of school violence. Engagement in bullying has been shown to have adverse effects on perpetrators and victims of bullying. In this study, the impact of bullying on well-being (quality of life/life satisfaction) was explored in a sample of elementary and middle school children (N = 4,331). Results suggest…

  19. Utilizing Model Eliciting Activities (MEA's) to engage middle school teachers and students in storm water management practices to mitigate human impacts of land development (United States)

    Tazaz, A.; Wilson, R. M.; Schoen, R.; Blumsack, S.; King, L.; Dyehouse, M.


    'The Integrating STEM Project' engaged 6-8 grade teachers through activities incorporating mathematics, science and technology incorporating both Next Generation Science Standards (NGSS) and Common Core State Standards-Mathematics (CCSS-Math). A group of researchers from Oceanography, Mathematics, and Education set out to provide middle school teachers with a 2 year intensive STEM integration professional development with a focus on environmental topics and to monitor the achievement outcomes in their students. Over the course of 2 years the researchers created challenging professional development sessions to expand teacher knowledge and teachers were tasked to transform the information gained during the professional development sessions for classroom use. One lesson resource kit presented to the teachers, which was directly applicable to the classroom, included Model Eliciting Activities (MEA's) to explore the positive and negative effects land development has on climate and the environment, and how land development impacts storm water management. MEA's were developed to encourage students to create models to solve complex problems and to allow teachers to investigate students thinking. MEA's are a great curriculum technique used in engineering fields to help engage students by providing hands on activities using real world data and problems. We wish to present the Storm Water Management Resource toolkit including the MEA and present the outcomes observed from student engagement in this activity.

  20. 2006 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report

    Energy Technology Data Exchange (ETDEWEB)

    A. L. Johnson; K. A. Gano


    The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act cleanup of National Priorities List waste sites at Hanford. One of the objectives of restoration is the revegetation of remediated waste sites to stabilize the soil and restore the land to native vegetation. The report documents the results of revegetation and mitigation monitoring conducted in 2006 and includes 11 revegetation/restoration projects, one revegetation/mitigation project, and 2 bat habitat mitigation projects.

  1. The effect of microphone wind noise on the amplitude modulation of wind turbine noise and its mitigation. (United States)

    Kendrick, Paul; von Hünerbein, Sabine; Cox, Trevor J


    Microphone wind noise can corrupt outdoor recordings even when wind shields are used. When monitoring wind turbine noise, microphone wind noise is almost inevitable because measurements cannot be made in still conditions. The effect of microphone wind noise on two amplitude modulation (AM) metrics is quantified in a simulation, showing that even at low wind speeds of 2.5 m/s errors of over 4 dBA can result. As microphone wind noise is intermittent, a wind noise detection algorithm is used to automatically find uncorrupted sections of the recording, and so recover the true AM metrics to within ±2/±0.5 dBA.

  2. Hydrogen-Rich Saline Attenuates Lipopolysaccharide-Induced Heart Dysfunction by Restoring Fatty Acid Oxidation in Rats by Mitigating C-Jun N-Terminal Kinase Activation. (United States)

    Tao, Bingdong; Liu, Lidan; Wang, Ni; Tong, Dongyi; Wang, Wei; Zhang, Jin


    Sepsis is common in intensive care units (ICU) and is associated with high mortality. Cardiac dysfunction complicating sepsis is one of the most important causes of this mortality. This dysfunction is due to myocardial inflammation and reduced production of energy by the heart. A number of studies have shown that hydrogen-rich saline (HRS) has a beneficial effect on sepsis. Therefore, we tested whether HRS prevents cardiac dysfunction by increasing cardiac energy. Four groups of rats received intraperitoneal injections of one of the following solutions: normal saline (NS), HRS, lipopolysaccharide (LPS), and LPS plus HRS. Cardiac function was measured by echocardiography 8 h after the injections. Gene and protein expression related to fatty acid oxidation (FAO) were measured by quantitative polymerase chain reaction (PCR) and Western blot analysis. The injection of LPS compromised heart function through decreased fractional shortening (FS) and increased left ventricular diameter (LVD). The addition of HRS increased FS, palmitate triphosphate, and the ratio of phosphocreatinine (PCr) to adenosine triphosphate (ATP) as well as decreasing LVD. The LPS challenge reduced the expression of genes related to FAO, including perioxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), perioxisome proliferator-activated receptor alpha (PPARα), Estrogen-related receptor alpha (ERRα), and their downstream targets, in mRNA and protein level, which were attenuated by HRS. However, HRS had little effect on glucose metabolism. Furthermore, HRS inhibited c-Jun N-terminal kinase (JNK) activation in the rat heart. Inhibition of JNK by HRS showed beneficial effects on LPS-challenged rats, at least in part, by restoring cardiac FAO.

  3. Sperm abnormalities induced by pre-pubertal exposure to cyclophosphamide are effectively mitigated by Moringa oleifera leaf extract. (United States)

    Nayak, G; Vadinkar, A; Nair, S; Kalthur, S G; D'Souza, A S; Shetty, P K; Mutalik, S; Shetty, M M; Kalthur, G; Adiga, S K


    Moringa oleifera L. is a medicinal plant with potential antioxidant property. This study was aimed at investigating the chemoprotective effect of Moringa oleifera leaf extract (MOE) on cyclophosphamide (CP)-induced testicular toxicity. Two-week-old male Swiss albino mice were intraperitoneally injected with phosphate-buffered saline, 50 mg kg(-1) of CP and 25 mg kg(-1) of MOE. In combination treatment, mice were injected with 25 mg kg(-1) of MOE 24 h prior to CP injection, 24 h prior and post-CP injection and 24 h post-CP injection for 5 consecutive days (10 mg kg(-1) ). Six weeks later, mice were sacrificed to assess epididymal sperm parameters. MOE alone did not have any significant effect on sperm parameters. However, acute injection of CP resulted in significant decline in motility (P < 0.001), increase in head abnormality (P < 0.01) and DNA damage (P < 0.05). Combining MOE with CP increased the sperm density, motility and reduced head defect and DNA damage, irrespective of the schedule and dosage of MOE. Administration of MOE prior to CP significantly elevated the level of superoxide dismutase and catalase with concomitant decrease in lipid peroxidation in the testicular tissue. In conclusion, MOE may have potential benefit in reducing the loss of male gonadal function following chemotherapy.

  4. Mitigation of self-excited oscillations at full load: CFD analysis of air admission and effects of runner design (United States)

    Chirkov, D.; Scherbakov, P.; Cherny, S.; Zakharov, A.; Skorospelov, V.; Turuk, P.


    In full and over load operating points some Francis turbines experience strong selfexcited pressure and power oscillations, which restrict the range of operation and maximum output of the turbine. Previously the authors proposed a 1D-3D two-phase model and numerical method for investigation of this phenomenon. In the present paper this model is further extended and applied to investigation of countermeasures, used for prevention of high load oscillations. First, the third phase - non-condensable air - is introduced into the model in order to investigate the effect of air admission. Then, several modifications of runner cone are examined, showing negligible effect on the amplitude and frequency of full load oscillations. Next, different modifications of runner blade shape are considered, giving different axial and circumferential velocity profiles downstream the runner. It is shown that variation of blade shape significantly affects the onset and intensity of self-excited oscillations. The obtained results indicate that proper runner design is able to eliminate high load instability without the need of air admission and reduction in turbine efficiency.

  5. Greenhouse gas mitigation in animal production

    DEFF Research Database (Denmark)

    De Boer, IJM; Cederberg, C; Eady, S;


    The animal food chain contributes significantly to emission of greenhouse gases (GHGs). We explored studies that addressed options to mitigate GHG emissions in the animal production chain and concluded that most studies focused on production systems in developed countries and on a single GHG....... They did not account for the complex interrelated effects on other GHGs or their relation with other aspects of sustainability, such as eutrophication, animal welfare, land use or food security. Current decisions on GHG mitigation in animal production, therefore, are hindered by the complexity...... and uncertainty of the combined effect of GHG mitigation options on climate change and their relation with other aspects of sustainability. There is an urgent need to integrate simulation models at animal, crop and farm level with a consequential life cycle sustainability assessment to gain insight...

  6. Mitigating tin whisker risks theory and practice

    CERN Document Server

    Handwerker, Carol A; Bath, Jasbir


    Discusses the growth mechanisms of tin whiskers and the effective mitigation strategies necessary to reduce whisker growth risks. This book covers key tin whisker topics, ranging from fundamental science to practical mitigation strategies. The text begins with a review of the characteristic properties of local microstructures around whisker and hillock grains to identify why these particular grains and locations become predisposed to forming whiskers and hillocks. The book discusses the basic properties of tin-based alloy finishes and the effects of various alloying elements on whisker formation, with a focus on potential mechanisms for whisker suppression or enhancement for each element. Tin whisker risk mitigation strategies for each tier of the supply chain for high reliability electronic systems are also described.

  7. Evaluating the effectiveness of active vehicle safety systems. (United States)

    Jeong, Eunbi; Oh, Cheol


    Advanced vehicle safety systems have been widely introduced in transportation systems and are expected to enhance traffic safety. However, these technologies mainly focus on assisting individual vehicles that are equipped with them, and less effort has been made to identify the effect of vehicular technologies on the traffic stream. This study proposed a methodology to assess the effectiveness of active vehicle safety systems (AVSSs), which represent a promising technology to prevent traffic crashes and mitigate injury severity. The proposed AVSS consists of longitudinal and lateral vehicle control systems, which corresponds to the Level 2 vehicle automation presented by the National Highway Safety Administration (NHTSA). The effectiveness evaluation for the proposed technology was conducted in terms of crash potential reduction and congestion mitigation. A microscopic traffic simulator, VISSIM, was used to simulate freeway traffic stream and collect vehicle-maneuvering data. In addition, an external application program interface, VISSIM's COM-interface, was used to implement the AVSS. A surrogate safety assessment model (SSAM) was used to derive indirect safety measures to evaluate the effectiveness of the AVSS. A 16.7-km freeway stretch between the Nakdong and Seonsan interchanges on Korean freeway 45 was selected for the simulation experiments to evaluate the effectiveness of AVSS. A total of five simulation runs for each evaluation scenario were conducted. For the non-incident conditions, the rear-end and lane-change conflicts were reduced by 78.8% and 17.3%, respectively, under the level of service (LOS) D traffic conditions. In addition, the average delay was reduced by 55.5%. However, the system's effectiveness was weakened in the LOS A-C categories. Under incident traffic conditions, the number of rear-end conflicts was reduced by approximately 9.7%. Vehicle delays were reduced by approximately 43.9% with 100% of market penetration rate (MPR). These results

  8. Compensatory interactions to stabilize multiple steady states or mitigate the effects of multiple deregulations in biological networks (United States)

    Yang, Gang; Campbell, Colin; Albert, Réka


    Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those corresponding to disease. Previous work designed compensatory interactions to stabilize an attractor of a Boolean network after single node damage. We generalize this method to a multinode damage scenario and to the simultaneous stabilization of multiple steady state attractors. We classify the emergent situations, with a special focus on combinatorial effects, and characterize each class through simulation. We explore how the structural and functional properties of the network affect its resilience and its possible repair scenarios. We demonstrate the method's applicability to two intracellular network models relevant to cancer. This work has implications in designing prevention strategies for complex disease.

  9. Mitigation of carbon dioxide by oleaginous microalgae for lipids and pigments production: Effect of light illumination and carbon dioxide feeding strategies. (United States)

    Thawechai, Tipawan; Cheirsilp, Benjamas; Louhasakul, Yasmi; Boonsawang, Piyarat; Prasertsan, Poonsuk


    Oleaginous microalgae Nannochloropsis sp. was selected as potential strain for CO2 mitigation into lipids and pigments. The synergistic effects of light intensity and photoperiod were evaluated to provide the adequate light energy for this strain. The saturation light intensity was 60μmol·photon·m(-2)s(-1). With full illumination, the biomass obtained was 0.850±0.16g·L(-1) with a lipid content of 44.7±1.2%. The pigments content increased with increasing light energy supply. Three main operating factors including initial cell concentration, CO2 content and gas flow rate were optimized through Response Surface Methodology. The feedings with low CO2 content at high gas flow rate gave the maximum biomass but with low lipid content. After optimization, the biomass and lipid production were increased up to 1.30±0.103g·L(-1) and 0.515±0.010g·L(-1), respectively. The CO2 fixation rate was as high as 0.729±0.04g·L(-1)d(-1). The fatty acids of Nannochloropsis sp. lipids were mainly C16-C18 indicating its potential use as biodiesel feedstocks.

  10. Space weathering effects in Diviner Lunar Radiometer multispectral infrared measurements of the lunar Christiansen Feature: Characteristics and mitigation (United States)

    Lucey, Paul G.; Greenhagen, Benjamin T.; Song, Eugenie; Arnold, Jessica A.; Lemelin, Myriam; Hanna, Kerri Donaldson; Bowles, Neil E.; Glotch, Timothy D.; Paige, David A.


    Multispectral infrared measurements by the Diviner Lunar Radiometer Experiment on the Lunar Renaissance Orbiter enable the characterization of the position of the Christiansen Feature, a thermal infrared spectral feature that laboratory work has shown is proportional to the bulk silica content of lunar surface materials. Diviner measurements show that the position of this feature is also influenced by the changes in optical and physical properties of the lunar surface with exposure to space, the process known as space weathering. Large rayed craters and lunar swirls show corresponding Christiansen Feature anomalies. The space weathering effect is likely due to differences in thermal gradients in the optical surface imposed by the space weathering control of albedo. However, inspected at high resolution, locations with extreme compositions and Christiansen Feature wavelength positions - silica-rich and olivine-rich areas - do not have extreme albedos, and fall off the albedo- Christiansen Feature wavelength position trend occupied by most of the Moon. These areas demonstrate that the Christiansen Feature wavelength position contains compositional information and is not solely dictated by albedo. An optical maturity parameter derived from near-IR measurements is used to partly correct Diviner data for space weathering influences.

  11. Mitigation of antagonistic effects on plant growth due to root co-colonization by dark septate endophytes and ectomycorrhiza. (United States)

    Reininger, Vanessa; Sieber, Thomas N


    Dark septate endophytes (DSE) are very common root colonizers of woody plant species. Ascomycetes of the Phialocephala fortinii s.l.-Acephala applanata species complex (PAC) are the main representatives of DSE fungi in forest ecosystems. PAC and mycorrhizal fungi share the same habitat, but interactions among PAC, mycorrhizal fungi and plants are poorly understood. We compared the effects of single and dual inoculation of Norway spruce seedlings with PAC and the ectomycorrhizal (ECM) fungus Hebeloma crustuliniforme on host growth, degree of mycorrhization and density of endophytic PAC biomass. Single colonization by H. crustuliniforme or PAC significantly reduced plant biomass. Dual colonization reduced or neutralized plant growth depression caused by single fungal colonization. The degree of mycorrhization was independent on PAC colonization, and mycorrhization significantly reduced endophytic PAC biomass. Plant biomass of dually colonized plants positively correlated with PAC biomass. These results demonstrate the ability of dual inoculation of PAC and H. crustuliniforme to neutralize plant growth depression caused by single fungal inoculation. Our explanations of enhanced plant growth in dually inoculated plants are the inhibition of PAC during root colonization by the ECM mantle and ECM-mediated access to plant growth-promoting nutrients resulting from the mineralization of the potting medium by PAC.

  12. Evaluating Mitigation Effects of Urban Heat Islands in a Historical Small Center with the ENVI-Met® Climate Model

    Directory of Open Access Journals (Sweden)

    Dario Ambrosini


    Full Text Available Urban morphology and increasing building density play a key role in the overall use of energy and promotion of environmental sustainability. The urban environment causes a local increase of temperature, a phenomenon known as Urban Heat Island (UHI. The purpose of this work is the study of the possible formation of an UHI and the evaluation of its magnitude, in the context of a small city, carried out with the ENVI-met® software. For this purpose, a simulation was needed, and this simulation is preparatory for a monitoring campaign on site, which will be held in the immediate future. ENVI-met® simulates the temporal evolution of several thermodynamics parameters on a micro-scale range, creating a 3D, non-hydrostatic model of the interactions between building-atmosphere-vegetation. The weather conditions applied simulate a typical Italian summer heat wave. Three different case-studies have been analyzed: Base Case, Cool Case and Green Case. Analysis of the actual state in the Base Case shows how even in an area with average building density, such as the old town center of a small city, fully developed UHI may rise with strong thermal gradients between built areas and open zones with plenty of vegetation. These gradients arise in a really tiny space (few hundreds of meters, showing that the influence of urban geometry can be decisive in the characterization of local microclimate. Simulations, carried out considering the application of green or cool roofs, showed small relevant effects as they become evident only in large areas heavily built up (metropolis subject to more intense climate conditions.

  13. Mitigation of effects of extreme drought during stage III of peach fruit development by summer pruning and fruit thinning. (United States)

    Lopez, Gerardo; Mata, Mercè; Arbones, Amadeu; Solans, Josep R; Girona, Joan; Marsal, Jordi


    A water deficit during stage III of fruit growth was established with the aim of determining if it is possible to achieve an improvement in tree water status by summer pruning and fruit thinning. The experiment was set up as a randomized block split-plot design across trials (irrigation) where pruning was assigned to the main plot and fruit thinning to the sub-plots. The irrigation treatments were (1) standard full irrigation (FI), and (2) suppression of irrigation during stage III of fruit growth until leaves visibly withered (LWI); the pruning treatments were (1) experimental summer pruning (EP), and (2) standard summer pruning (CP); and three fruit thinning intensities were applied to facilitate analysis of the effects of the treatments in relation to fruit load. Changes in amount of light intercepted and in tree stem water potential (Psi stem) were evaluated. The EP treatment reduced the amount of light intercepted by the tree. In the FI treatment, there was a significant reduction in fruit growth measured as both water accumulation and dry mass accumulation. Under FI conditions, reductions in fruit load as a result of EP were not accompanied by a significant improvement in Psi stem. In the LWI treatment, EP produced a significant improvement of 0.17 MPa in Psi stem, but there was no improvement in fruit growth compared with CP trees. A reduction in fruit load from 350 (commercial load) to 150 per tree significantly improved Psi stem by 0.3 MPa at the end of stage III of fruit growth. These results indicate that improvements in water status in response to pruning may be insufficient to promote fruit growth if the pruned trees are unable to provide an adequate supply of assimilates to the developing fruits.

  14. Existence of glia mitigated ketamine-induced neurotoxicity in neuron-glia mixed cultures of neonatal rat cortex and the glia-mediated protective effect of 2-PMPA. (United States)

    Zuo, Daiying; Wang, Chengna; Li, Zengqiang; Lin, Li; Duan, Zhenfang; Qi, Huan; Li, Lin; Sun, Feng; Wu, Yingliang


    The present study compared ketamine-induced neurotoxicity in the neuron-glia mixed cultures and neuronal cultures and further explored the neuroprotective effect of the NAAG peptidase inhibitor 2-(phosphonomethyl) pentanedioic acid (2-PMPA). Firstly, Rosenfeld's staining and immunofluorescence staining of microtubule-associated protein 2 (MAP2) and glial fibrillary acidic protein (GFAP) were used to address the difference of morphology in the mixed cultures and neuronal cultures. Our results showed that neurons and astrocytes grew in good conditions. The ratio of neurons and astrocytes in the mixed cultures was around 1:1, and the purity of neurons in the neuronal cultures is 91.3%. Furthermore, ketamine was used to test the hypothesis that the presence of a higher proportion of glia in the mixed cultures would be protective against ketamine-induced neurotoxicity in the mixed cultures compared with neuronal cultures. The results showed that ketamine-induced morphological changes, cell viability decrease and lactate dehydrogenase (LDH) levels increase were significantly mitigated in neuron-glia mixed cultures compared with neuronal cultures. Furthermore, 2-PMPA was included to further explore efficient protective drug for ketamine-induced neurotoxicity. Our results showed that 2-PMPA reduced ketamine-induced decrease of cell viability and increase of LDH levels in the mixed cultures but not in the neuronal cultures. Further morphological changes of neurons and astrocytes also indicated that 2-PMPA could improve ketamine damaged neurons in the mixed cultures instead of neuronal cultures. These results indicate that glia protect neurons from ketamine-induced neurotoxicity. These data further suggest that glia mediate the neuroprotective effect of 2-PMPA and 2-PMPA has the potential to treat ketamine-induced neurotoxicity in vivo. Delineating the mechanisms underlying the communication between neurons and glia and the neuroprotective effects of 2-PMPA in the mixed

  15. Maternal education mitigates the negative effects of higher income on the double burden of child stunting and maternal overweight in rural Mexico. (United States)

    Leroy, Jef L; Habicht, Jean-Pierre; González de Cossío, Teresa; Ruel, Marie T


    Globally, the rate at which maternal overweight and obesity increase with rising wealth is higher than the accompanying decline in the prevalence of child stunting, resulting in the double burden of malnutrition. The positive association between household wealth and child linear growth is larger in households with a more educated mother. However, whether a similar positive and synergistic association between maternal education and household wealth is observed for maternal body weight is unknown. Our objective was to assess the potential protective role of maternal education in the etiology of the double burden of malnutrition (stunted child with an overweight mother). We used data on 1547 nonpregnant mothers (aged 18-49 y) and their children (aged 0-5 y) collected in a cross-sectional survey in 235 rural communities in southern Mexico. Child height-for-age Z-score and maternal body weight were regressed on household wealth, women's schooling, and the interaction between both, controlling for relevant covariates. A similar model was used for the prevalence of double-burden pairs (stunted child with an overweight mother). In mothers with less than primary school, a doubling in wealth was not associated with improved child's height but was associated with an increase in mother's weight (3.7%, P effectively mitigated the negative effects of household wealth on the prevalence of double-burden households in rural Mexico. Where maternal schooling is low, poverty reduction must be accompanied by effective behavior change communication to prevent child stunting and to protect women from unhealthy weight gain.

  16. High effective silica fume alkali activator

    Indian Academy of Sciences (India)

    Vladimír Živica


    Growing demands on the engineering properties of cement based materials and the urgency to decrease unsuitable ecologic impact of Portland cement manufacturing represent significant motivation for the development of new cement corresponding to these aspects. One category represents prospective alkali activated cements. A significant factor influencing their properties is alkali activator used. In this paper we present a new high effective alkali activator prepared from silica fume and its effectiveness. According to the results obtained this activator seems to be more effective than currently used activators like natrium hydroxide, natrium carbonate, and water glass.

  17. Flood risk mitigation and anthropogenic modifications of a coastal plain in southern Italy: combined effects over the past 150 years

    Directory of Open Access Journals (Sweden)

    O. Petrucci


    Full Text Available A study of the effects of human modification of a coastal plain mainly involving land reclamation and flood protection is proposed. The approach involves historical, geomorphological and hydrological data as a whole, taking into account the equilibrium of rivers, plains and coastal areas.

    The test area, a telling example of profound economic and social transformation of a coastal plain, is the Piana di Sibari (Calabria, southern Italy, subject to major human modifications over the last 150 years. The study area, at most 300 m a.s.l., is 450 km2 wide and comprises 24 hydrographic basins.

    The approach is based on the creation and analysis of four databases: 1 a historical series of geo-coded flood damage (DAMAGES database, concerning damaging floods which occurred over the past few centuries in the study area; 2 a geocoded series of protection works for land reclamation, protection from floods and improvement of soil stability in steep areas (WORKS database, gathered from the archives of the agencies that carried out the works, organized in a GIS-format; 3 a historical series of maximum flood discharges and extreme rainy events (HYMAX database aimed at defining the trends of occurrence and the intensity of flooding; 4 a coastal line position and migration over time (COASTAL database, created using mainly literature data based on discontinuous data such as historical maps and images.

    The work describes the complex succession of floods, protection and reclamation works, human transformation of the plain and major land use changes over the last two centuries in the test area. The new characteristics of the plain and its modifications, including major engineering works, land-use transformation and urbanisation, are illustrated. The damaging floods of the last 200 years, the modifications of runoff and flooding due to works built over the basins, hydrological data and the records concerning coastal

  18. Effective mitigation of nitrate leaching and nitrous oxide emissions in intensive vegetable production systems using a nitrification inhibitor, dicyandiamide

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Min; Sun, Xuecheng; Hu, Chengxiao; Tan, Qiling; Zhao, Changsheng [Huazhong Agricultural Univ., Wuhan (China). Key Lab. of Subtropical Agricultural Resources and Environment; Di, Hong J. [Lincoln Univ., Christchurch (New Zealand). Center for Soil and Environment Research


    Vegetable production is one of the most intensive agricultural systems with high rates of nitrogen (N) fertilizer use and irrigation, conditions conducive for nitrate (NO{sub 3}{sup -}) leaching, and nitrous oxide (N{sub 2}O) emissions. The objective of this study was to determine the effectiveness of a nitrification inhibitor, dicyandiamide (DCD), in decreasing NO{sub 3}{sup -} leaching and N{sub 2}O emissions in vegetable production systems. Twenty-four undisturbed soil monolith lysimeters (610 mm in diameter; 700 mm in depth; surface area, 0.29 m{sup 2}) with two different soils, Huangzongrang (alfisol) and Chaotu (fluvisols), were collected and installed in a field lysimeter facility in Central China under irrigated vegetable production conditions. Urea fertilizer was applied at 650 kg N ha{sup -1}, and DCD was applied at 10 kg ha{sup -1} to the lysimeters planted with three kinds of vegetables (capsicum, Capsicum annuum L.; amaranth, Amaranthus mangostanus L.; radish, Raphanus sativus L.). The results showed that DCD reduced NO3- leaching by 58.5% and 36.2% and N{sub 2}O emissions factor by 83.8% and 72.7% in the two soils. The average NO{sub 3}{sup -}-N concentration in the drainage water was decreased from 4.9 mg NL{sup -1} to 2.3 mg NL{sup -1} and from 4.4 mg NL{sup -1} to 3.3 mg NL{sup -1}, in the Huangzongrang and Chaotu soils, respectively. In addition to the environmental benefits, the use of DCD also increased the yields of capsicum and radish in alfisol soil significantly (P < 0.01); only the amaranth yield in fluvisol soil was declined (P < 0.01), and the other vegetables yields were not affected. Total N concentrations of the three vegetables were increased significantly (P < 0.01) with the application of DCD with urea compared with urea alone. These results showed that the nitrification inhibitor DCD has the potential to significantly reduce NO{sub 3}{sup -} leaching and N{sub 2}O emissions and to make vegetable farming more environmentally

  19. Handbook of Climate Change Mitigation

    CERN Document Server

    Seiner, John; Suzuki, Toshio; Lackner, Maximilian


    There is a mounting consensus that human behavior is changing the global climate and its consequence could be catastrophic. Reducing the 24 billion metric tons of carbon dioxide emissions from stationary and mobile sources is a gigantic task involving both technological challenges and monumental financial and societal costs. The pursuit of sustainable energy resources, environment, and economy has become a complex issue of global scale that affects the daily life of every citizen of the world. The present mitigation activities range from energy conservation, carbon-neutral energy conversions, carbon advanced combustion process that produce no greenhouse gases and that enable carbon capture and sequestion, to other advanced technologies. From its causes and impacts to its solutions, the issues surrounding climate change involve multidisciplinary science and technology. This handbook will provide a single source of this information. The book will be divided into the following sections: Scientific Evidence of Cl...

  20. Stray voltage mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Jamali, B.; Piercy, R.; Dick, P. [Kinetrics Inc., Toronto, ON (Canada). Transmission and Distribution Technologies


    This report discussed issues related to farm stray voltage and evaluated mitigation strategies and costs for limiting voltage to farms. A 3-phase, 3-wire system with no neutral ground was used throughout North America before the 1930s. Transformers were connected phase to phase without any electrical connection between the primary and secondary sides of the transformers. Distribution voltage levels were then increased and multi-grounded neutral wires were added. The earth now forms a parallel return path for the neutral current that allows part of the neutral current to flow continuously through the earth. The arrangement is responsible for causing stray voltage. Stray voltage causes uneven milk production, increased incidences of mastitis, and can create a reluctance to drink water amongst cows when stray voltages are present. Off-farm sources of stray voltage include phase unbalances, undersized neutral wire, and high resistance splices on the neutral wire. Mitigation strategies for reducing stray voltage include phase balancing; conversion from single to 3-phase; increasing distribution voltage levels, and changing pole configurations. 22 refs., 5 tabs., 13 figs.

  1. Mitigative Effect of LaCl3 on the Seedling Growth of Dendranthema morifolium Under CrCl3 Stress%LaCl3对菊花幼苗生长过程中CrCl3胁迫的缓解效应

    Institute of Scientific and Technical Information of China (English)

    张子学; 李文文; 石海涛; 胡能兵; 崔广荣


    以滁菊为材料,采用组织培养的方法,研究LaCl3对滁菊生长过程中CrCl3胁迫的缓解效应,结果表明,在一定范围内LaCl3对CrCl3胁迫滁菊的生根数量、根长、株高和植株重量均具有缓解效应。当CrCl3胁迫浓度的提高到250mg/L时,其缓解效应不明显。同时,在一定范围内LaCl3对CrCl3胁迫滁菊的POD和SOD同工酶的活性均有促进作用,随着CrCl3胁迫浓度的提高,POD同工酶活性及其表达种类逐渐增加,SOD同工酶活性及其表达种类无明显变化。%By using tissue culture method, the mitigative effect of LaCl3 on the seedling growth of Dendranthema morifolium under CrCl3 stress was studied. The results showed that in the certain range, the mitigative effects on root length and root number and plant height, fresh weight were obvious, and when CrCl3 concentration reached 250mg/L, the mitigative effect of LaCl3 was not obvious. The isozymes activity of POD and SOD promoted by LaCl3 on the seedling under CrCl3 stress, and POD isozymes activity increased and expression types enhanced, while the SOD isozymes activity and expression types did not change obviously with the increasing of concentration of CrCl3 stress.

  2. Earthquake risk mitigation projects in central asia and india (United States)

    Hausler, E.; Petal, M.; Tobin, T.; Tucker, B.; Gupta, M.; Sharma, A.; Shaw, R.


    In the fall of 2002, GeoHazards International (GHI), a California-based nonprofit organization, launched two 3-year projects, each funded by the U.S. Agency for International Development, to improve the earthquake risk management of 23 cities in Central Asia and India. The objectives of these projects are to: * Assess the earthquake risk of each city, * Identify the most effective risk mitigation options for each city, * Raise awareness of that risk and those mitigation options, and * Initiate mitigation activities in some of these cities. A critical characteristic of these projects is that leaders of each local community will be deeply involved in realizing all four objectives. GHI will work with, in addition to local authorities, national government, academic and non-governmental organizations. In India, GHI’s partners are the Disaster Management Planning Hyogo Office, United Nations Centre for Regional Development (UNCRD) of Kobe, Japan, and the Sustainable Environment and Ecological Development Society (SEEDS), of Delhi, India. In India, we will work in 20 cities that were chosen, in a February 1, 2002 workshop (sponsored by Munich Reinsurance Company) in Delhi; the cities were selected by Indian earthquake professionals on the basis of the cities’ population, hazard, and economic, cultural and political significance. In Central Asia, we will focus on Tashkent, Uzbekistan; Dushanbe, Tadzhikistan; and Almaty, Kazakstan. GHI and its partners are looking for other organizations that would like to collaborate on these projects.

  3. Mitigating GHG emissions from ruminant livestock systems


    Klumpp, Katja; Doreau, Michel; Faverdin, Philippe; Jeuffroy, Marie-Helene; Bamière, Laure; Pardon, Lenaïc; Soussana, Jean-François; Pellerin, Sylvain


    Improving the net GHG budget of ruminant livestock systems without a reduction in productivity and economic sustainability, requires effective mitigation options in terms of abatement potential and costs. Grasslands and grassland management have a large potential to mitigate livestock GHG emissions at a low (or even negative) cost. A synthesis of eddy flux covariance data (i.e. 189 site years) shows on a mean net carbon storage equal to 0.76 ±0.1 MgC m-2yr-1, indicating a significant carbon s...

  4. Evaluation of the Effects of Mitigation on Methane and Ammonia Production by Using Origanum vulgare L. and Rosmarinus officinalis L. Essential Oils on in Vitro Rumen Fermentation Systems

    Directory of Open Access Journals (Sweden)

    Gabriella Cobellis


    Full Text Available The effects of increasing concentrations of oregano (Origanum vulgare L. and rosemary (Rosmarinus officinalis L. essentials oil (EO on ruminal gas emissions were tested in vitro using 50 mL serum bottles. Each bottle contained a 200 mg substrate (alfalfa hay and corn meal 1:1 and a 20 mL solution composed of a buffered medium and rumen fluid (1:2. The percentage of ruminal fermentation products was quantified by an infrared analyzer. The reduction of total gas production was 6% and 9% respectively when using the 1.5 and 2.0 g/L oregano EO measurements. The reduction of methane production was 55%, 72% and 71% respectively with regard to the 1.0, 1.5 and 2.0 g/L oregano EO doses, while rosemary EO (2.0 g/L reduced the methane production by 9%. The production of ammonia was significantly reduced (59%–78% by all treatments with the exception of rosemary EO at the lowest dose. Dry matter and neutral detergent fiber degradability was reduced by most of the treatments (respectively 4%–9% and 8%–24%. The total volatile fatty acids (VFA concentration was markedly decreased by oregano EO and was not affected by rosemary EO. Both EOs mitigated rumen fermentations, but oregano EO gave rise to the highest reduction in methane and ammonia production. However, further research is needed to evaluate the use of these essential oils as dietary supplements by taking into account the negative effects on feed degradability.

  5. The effect of climate change, population distribution, and climate mitigation on building energy use in the U.S. and China

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yuyu; Eom, Jiyong; Clarke, Leon E.


    A changing climate will affect the energy system in a number of ways, one of which is through changes in demands for heating and cooling in buildings. Understanding the potential effect of climate on heating and cooling demands must take into account not only the manner in which the building sector might evolve over time - including, for example, movements from rural to urban environments in developing countries - but also important uncertainty about the nature of climate change itself and the growth and movements of populations over time. In this study, we explored the uncertainty in climate change impacts on heating and cooling by constructing estimates of heating and cooling degree days for both a reference (no-policy) scenario and a climate mitigation scenario built from 0.5 degree latitude by 0.5 degree longitude resolution output from three different Global Climate Models (GCMs) and three gridded scenarios of population distribution. The implications that changing climate and population distribution might have for building energy consumption in the U.S. and China were then explored by using the heating and cooling degree days results as inputs to a detailed, building energy model, nested in the long-term global integrated assessment framework, Global Change Assessment Model (GCAM). Across the climate models and population distribution scenarios, the results indicate that unabated climate change would cause total final energy consumption to decrease modestly in both U.S. and China buildings by the end of the century, as decreased heating consumption is more than balanced by increased cooling using primarily electricity. However, the results also indicate that when indirect emissions from the power sector are also taken into account, climate change may have negligible effect on building sector CO2 emissions in the two countries. The variation in results due to variation of population distribution is noticeably smaller than variation due to the use of different

  6. Effects of Preoperative Non-Steroidal Anti-Inflammatory Drugs on Pain Mitigation and Patients’ Shoulder Performance Following Rotator Cuff Repair

    Directory of Open Access Journals (Sweden)

    Alireza Rouhani


    Full Text Available Purpose: Pain is one of the most important factors adversely affecting clinical outcomes of operated patients. The present study aims at evaluating effects of preoperative COX2 non-steroidal anti-inflammatory inhibitors on pain mitigation and performance of patients with shoulder rotator cuff tear. Methods: This case-control study was conducted on 60 patients suffering from rotator cuff injury candidate for arthroscopic repair. The patients were classified in two parallel and matched groups. One group (case group was treated using Celecoxib (200mg/12h started 48 hours before surgery and continued for 10 days after operation. In the control group, the placebo was prescribed in the same way. Postoperative pain, side effects, sleep disturbance, and short-term outcomes were compared between two groups using DASH questionnaire. Results: Postoperative pain in the Celecoxib group significantly decreased in comparison with the control one. The difference was statistically meaningful (P<0.001. Well motion ability was seen in 80% of patients of the Celecoxib group. It was 26.6% in the placebo group since pain inhibited them from exercising more motions. In this regard, there was a statistically meaningful difference between these two groups (P=0.02. Sleep disturbance was meaningfully at higher levels in the placebo group (P=0.001. Following up the patients for three months, it was made clear that performance of the Celecoxib group was better than that of the placebo one. Conclusion: COX2 inhibitors are well efficient in patients’ pain management after arthroscopic rotator cuff repair surgery. It results in less life complications, less sleep disturbances, improvement of patients’ short-term clinical outcome, and more quick recovery.

  7. Long-term field data and climate-habitat models show that orangutan persistence depends on effective forest management and greenhouse gas mitigation.

    Directory of Open Access Journals (Sweden)

    Stephen D Gregory

    Full Text Available BACKGROUND: Southeast Asian deforestation rates are among the world's highest and threaten to drive many forest-dependent species to extinction. Climate change is expected to interact with deforestation to amplify this risk. Here we examine whether regional incentives for sustainable forest management will be effective in improving threatened mammal conservation, in isolation and when combined with global climate change mitigation. METHODOLOGY/PRINCIPAL FINDINGS: Using a long time-series of orangutan nest counts for Sabah (2000-10, Malaysian Borneo, we evaluated the effect of sustainable forest management and climate change scenarios, and their interaction, on orangutan spatial abundance patterns. By linking dynamic land-cover and downscaled global climate model projections, we determine the relative influence of these factors on orangutan spatial abundance and use the resulting statistical models to identify habitat crucial for their long-term conservation. We show that land-cover change the degradation of primary forest had the greatest influence on orangutan population size. Anticipated climate change was predicted to cause reductions in abundance in currently occupied populations due to decreased habitat suitability, but also to promote population growth in western Sabah by increasing the suitability of presently unoccupied regions. CONCLUSIONS/SIGNIFICANCE: We find strong quantitative support for the Sabah government's proposal to implement sustainable forest management in all its forest reserves during the current decade; failure to do so could result in a 40 to 80 per cent regional decline in orangutan abundance by 2100. The Sabah orangutan is just one (albeit iconic example of a forest-dependent species that stands to benefit from sustainable forest management, which promotes conservation of existing forests.

  8. A new mechanism of macrophyte mitigation: how submerged plants reduce malathion's acute toxicity to aquatic animals. (United States)

    Brogan, William R; Relyea, Rick A


    A growing body of evidence suggests that aquatic plants can mitigate the toxicity of insecticides to sensitive aquatic animals. The current paradigm is that this ability is driven primarily by insecticide sorption to plant tissues, especially for hydrophobic compounds. However, recent work shows that submerged plants can strongly mitigate the toxicity of the relatively hydrophilic insecticide malathion, despite the fact that this compound exhibits a slow sorption rate to plants. To examine this disparity, we tested the hypothesis that the mitigating effect of submerged plants on malathion's toxicity is driven primarily by the increased water pH from plant photosynthesis causing the hydrolysis of malathion, rather than by sorption. To do this, we compared zooplankton (Daphnia magna) survival across five environmentally relevant malathion concentrations (0, 1, 4, 6, or 36 μg L(-1)) in test containers where we chemically manipulated water pH in the absence of plants or added the submerged plant (Elodea canadensis) but manipulated plant photosynthetic activity via shading or no shading. We discovered that malathion was equally lethal to Daphnia at all concentrations tested when photosynthetically inactive (i.e. shaded) plants were present (pH at time of dosing=7.8) or when pH was chemically decreased (pH=7.7). In contrast, when photosynthetically active (i.e. unshaded) plants were present (pH=9.8) or when pH was chemically increased (pH=9.5), the effects of 4 and 6 μg L(-1) of malathion on Daphnia were mitigated strongly and to an equal degree. These results demonstrate that the mitigating effect of submerged plants on malathion's toxicity can be explained entirely by a mechanism of photosynthesizing plants causing an increase in water pH, resulting in rapid malathion hydrolysis. Our findings suggest that current ecotoxicological models and phytoremediation strategies may be overlooking a critical mechanism for mitigating pesticides.

  9. Playing against nature: improving earthquake hazard mitigation (United States)

    Stein, S. A.; Stein, J.


    The great 2011 Tohoku earthquake dramatically demonstrated the need to improve earthquake and tsunami hazard assessment and mitigation policies. The earthquake was much larger than predicted by hazard models, and the resulting tsunami overtopped coastal defenses, causing more than 15,000 deaths and $210 billion damage. Hence if and how such defenses should be rebuilt is a challenging question, because the defences fared poorly and building ones to withstand tsunamis as large as March's is too expensive,. A similar issue arises along the Nankai Trough to the south, where new estimates warning of tsunamis 2-5 times higher than in previous models raise the question of what to do, given that the timescale on which such events may occur is unknown. Thus in the words of economist H. Hori, "What should we do in face of uncertainty? Some say we should spend our resources on present problems instead of wasting them on things whose results are uncertain. Others say we should prepare for future unknown disasters precisely because they are uncertain". Thus society needs strategies to mitigate earthquake and tsunami hazards that make economic and societal sense, given that our ability to assess these hazards is poor, as illustrated by highly destructive earthquakes that often occur in areas predicted by hazard maps to be relatively safe. Conceptually, we are playing a game against nature "of which we still don't know all the rules" (Lomnitz, 1989). Nature chooses tsunami heights or ground shaking, and society selects the strategy to minimize the total costs of damage plus mitigation costs. As in any game of chance, we maximize our expectation value by selecting the best strategy, given our limited ability to estimate the occurrence and effects of future events. We thus outline a framework to find the optimal level of mitigation by balancing its cost against the expected damages, recognizing the uncertainties in the hazard estimates. This framework illustrates the role of the

  10. Flood Risk, Flood Mitigation, and Location Choice: Evaluating the National Flood Insurance Program's Community Rating System. (United States)

    Fan, Qin; Davlasheridze, Meri


    Climate change is expected to worsen the negative effects of natural disasters like floods. The negative impacts, however, can be mitigated by individuals' adjustments through migration and relocation behaviors. Previous literature has identified flood risk as one significant driver in relocation decisions, but no prior study examines the effect of the National Flood Insurance Program's voluntary program-the Community Rating System (CRS)-on residential location choice. This article fills this gap and tests the hypothesis that flood risk and the CRS-creditable flood control activities affect residential location choices. We employ a two-stage sorting model to empirically estimate the effects. In the first stage, individuals' risk perception and preference heterogeneity for the CRS activities are considered, while mean effects of flood risk and the CRS activities are estimated in the second stage. We then estimate heterogeneous marginal willingness to pay (WTP) for the CRS activities by category. Results show that age, ethnicity and race, educational attainment, and prior exposure to risk explain risk perception. We find significant values for the CRS-creditable mitigation activities, which provides empirical evidence for the benefits associated with the program. The marginal WTP for an additional credit point earned for public information activities, including hazard disclosure, is found to be the highest. Results also suggest that water amenities dominate flood risk. Thus, high amenity values may increase exposure to flood risk, and flood mitigation projects should be strategized in coastal regions accordingly.

  11. The Role of Science in Advising the Decision Making Process: A Pathway for Building Effective Climate Change Mitigation Policies in Mexico at the Local Level

    Directory of Open Access Journals (Sweden)

    Roberto Barraza


    Full Text Available This study examines a pathway for building urban climate change mitigation policies by presenting a multi-dimensional and transdisciplinary approach in which technical, economic, environmental, social, and political dimensions interact. Now, more than ever, the gap between science and policymaking needs to be bridged; this will enable judicious choices to be made in regarding energy and climate change mitigation strategies, leading to positive social impacts, in particular for the populations at-risk at the local level. Through a case study in Juarez, Chihuahua, Mexico, we propose a multidimensional and transdisciplinary approach with the role of scientist as policy advisers to improve the role of science in decision-making on mitigation policies at the local level in Mexico.

  12. The Role of Science in Advising the Decision Making Process: A Pathway for Building Effective Climate Change Mitigation Policies in Mexico at the Local Level (United States)

    Barraza, Roberto; Velazquez-Angulo, Gilberto; Flores-Tavizón, Edith; Romero-González, Jaime; Huertas-Cardozo, José Ignacio


    This study examines a pathway for building urban climate change mitigation policies by presenting a multi-dimensional and transdisciplinary approach in which technical, economic, environmental, social, and political dimensions interact. Now, more than ever, the gap between science and policymaking needs to be bridged; this will enable judicious choices to be made in regarding energy and climate change mitigation strategies, leading to positive social impacts, in particular for the populations at-risk at the local level. Through a case study in Juarez, Chihuahua, Mexico, we propose a multidimensional and transdisciplinary approach with the role of scientist as policy advisers to improve the role of science in decision-making on mitigation policies at the local level in Mexico. PMID:27128933

  13. The Role of Science in Advising the Decision Making Process: A Pathway for Building Effective Climate Change Mitigation Policies in Mexico at the Local Level. (United States)

    Barraza, Roberto; Velazquez-Angulo, Gilberto; Flores-Tavizón, Edith; Romero-González, Jaime; Huertas-Cardozo, José Ignacio


    This study examines a pathway for building urban climate change mitigation policies by presenting a multi-dimensional and transdisciplinary approach in which technical, economic, environmental, social, and political dimensions interact. Now, more than ever, the gap between science and policymaking needs to be bridged; this will enable judicious choices to be made in regarding energy and climate change mitigation strategies, leading to positive social impacts, in particular for the populations at-risk at the local level. Through a case study in Juarez, Chihuahua, Mexico, we propose a multidimensional and transdisciplinary approach with the role of scientist as policy advisers to improve the role of science in decision-making on mitigation policies at the local level in Mexico.


    Directory of Open Access Journals (Sweden)

    George D. Curtis


    Full Text Available Hawai`i has a long, though sporadic history of deadly tsunami attacks.Since the 1946 tsunami disaster the State of Hawaii has developed increasingly sophisticated and effective mitigation strategies. The evolution and operation of these strategies is described in this paper. Tsunamis will no longer be Hawai`i’s deadliest natural hazard.

  15. On Mitigating Distributed Denial of Service Attacks (United States)

    Gao, Zhiqiang


    Denial of service (DoS) attacks and distributed denial of service (DDoS) attacks are probably the most ferocious threats in the Internet, resulting in tremendous economic and social implications/impacts on our daily lives that are increasingly depending on the well-being of the Internet. How to mitigate these attacks effectively and efficiently…

  16. Albeni Falls Wildlife Mitigation : Annual Report 2002.

    Energy Technology Data Exchange (ETDEWEB)

    Terra-Berns, Mary


    The Albeni Falls Interagency Work Group continued to actively engage in implementing wildlife mitigation actions in 2002. Regular Work Group meetings were held to discuss budget concerns affecting the Albeni Falls Wildlife Mitigation Program, to present potential acquisition projects, and to discuss and evaluate other issues affecting the Work Group and Project. Work Group members protected 1,386.29 acres of wildlife habitat in 2002. To date, the Albeni Falls project has protected approximately 5,914.31 acres of wildlife habitat. About 21% of the total wildlife habitat lost has been mitigated. Administrative activities have increased as more properties are purchased and continue to center on restoration, operation and maintenance, and monitoring. In 2001, Work Group members focused on development of a monitoring and evaluation program as well as completion of site-specific management plans. This year the Work Group began implementation of the monitoring and evaluation program performing population and plant surveys, data evaluation and storage, and map development as well as developing management plans. Assuming that the current BPA budget restrictions will be lifted in the near future, the Work Group expects to increase mitigation properties this coming year with several potential projects.

  17. 水杨酸对盐胁迫下油菜幼苗生长抑制的缓解效应%Effects of salicylic acid mitigating on the inhibition of salt stress to the rape seedling growth

    Institute of Scientific and Technical Information of China (English)

    常云霞; 陈璨; 王少尉; 陈龙


    以油菜品种"美国巨荚油王"为材料,采用室内水培实验研究了不同浓度SA处理对0.1mmol/LNaCl胁迫下油菜幼苗生长的影响.结果表明:盐胁迫下,油菜幼苗叶片内叶绿素含量及过氧化物酶活性明显降低,脯氨酸和丙二醛(MDA)含量明显增加.外施SA明显提高了盐胁迫下油菜幼苗叶片内叶绿素含量、过氧化物酶活性及脯氨酸含量,使膜脂过氧化产物MDA含量明显降低.外施SA可以缓解盐胁迫对幼苗生长的抑制作用,并以0.15mmol/L,0.2mmol/L SA缓解效果最好.%Using rape "American oil giant pods king"as the material, effects of the different concentration of salicylic acid on the growth of rape seedling under 0.1 mmol/L NaC1 stress was studied by hydroponic culture. The results showed as follow: under salt stress, the content of chlorophyll and the activity of POD were significantly decreased than those control, the content of proline and MDA were significantly increased. Exogenous SA can effectively mitigate the harmful effects from salt stress on plants, and the effect of 0.15 mmol/L and 0.2 mmol/L SA were optimal.

  18. Effectiveness of worksite physical activity counseling

    NARCIS (Netherlands)

    Proper, K.I.


    The aim of this thesis was to describe the effectiveness of a particular worksite physical activity intervention involving individual counseling of workers. First, a summary of the existing literature is given as to the effectiveness of worksite physical activity programs. A strong evidence was foun

  19. Novel Ice Mitigation Methods (United States)


    After the loss of Columbia, there was great concern in the Space Shuttle program for the impact of debris against the leading edges of the Orbiter wings. It was quickly recognized that, in addition to impacts by foam, ice that formed on the liquid-oxygen bellows running down the outside of the External Tank could break free during launch and hit this sensitive area. A Center Director s Discretionary Fund (CDDF) project would concentrate on novel ideas that were potentially applicable. The most successful of the new concepts for ice mitigation involved shape memory alloy materials. These materials can be bent into a given shape and, when heated, will return to their original shape.

  20. 44 CFR 201.6 - Local Mitigation Plans. (United States)


    ... HOMELAND SECURITY DISASTER ASSISTANCE MITIGATION PLANNING § 201.6 Local Mitigation Plans. The local... essential to the development of an effective plan. In order to develop a more comprehensive approach to... appropriate, of existing plans, studies, reports, and technical information. (c) Plan content. The plan...


    Directory of Open Access Journals (Sweden)

    J. A. Principe


    Full Text Available The impact of climate change in the Philippines was examined in the country's largest basin–the Cagayan River Basin–by predicting its sediment yield for a long period of time. This was done by integrating the Soil and Water Assessment Tool (SWAT model, Remote Sensing (RS and Geographic Information System (GIS. A set of Landsat imageries were processed to include an atmospheric correction and a filling procedure for cloud and cloud-shadow infested pixels was used to maximize each downloaded scene for a subsequent land cover classification using Maximum Likelihood classifier. The Shuttle Radar Topography Mission (SRTM-DEM was used for the digital elevation model (DEM requirement of the model while ArcGIS™ provided the platform for the ArcSWAT extension, for storing data and displaying spatial data. The impact of climate change was assessed by varying air surface temperature and amount of precipitation as predicted in the Intergovernmental Panel on Climate Change (IPCC scenarios. A Nash-Sutcliff efficiency (NSE > 0.4 and coefficient of determination (R2 > 0.5 for both the calibration and validation of the model showed that SWAT model can realistically simulate the hydrological processes in the study area. The model was then utilized for land cover change and climate change analyses and their influence on sediment yield. Results showed a significant relationship exists among the changes in the climate regime, land cover distributions and sediment yield. Finally, the study suggested land cover distribution that can potentially mitigate the serious negative effects of climate change to a regional watershed's sediment yield.

  2. Exploring Climate Change Effects on Watershed Sediment Yield and Land Cover-Based Mitigation Measures Using Swat Model, RS and Gis: Case of Cagayan River Basin, Philippines (United States)

    Principe, J. A.


    The impact of climate change in the Philippines was examined in the country's largest basin-the Cagayan River Basin-by predicting its sediment yield for a long period of time. This was done by integrating the Soil and Water Assessment Tool (SWAT) model, Remote Sensing (RS) and Geographic Information System (GIS). A set of Landsat imageries were processed to include an atmospheric correction and a filling procedure for cloud and cloud-shadow infested pixels was used to maximize each downloaded scene for a subsequent land cover classification using Maximum Likelihood classifier. The Shuttle Radar Topography Mission (SRTM)-DEM was used for the digital elevation model (DEM) requirement of the model while ArcGIS™ provided the platform for the ArcSWAT extension, for storing data and displaying spatial data. The impact of climate change was assessed by varying air surface temperature and amount of precipitation as predicted in the Intergovernmental Panel on Climate Change (IPCC) scenarios. A Nash-Sutcliff efficiency (NSE) > 0.4 and coefficient of determination (R2) > 0.5 for both the calibration and validation of the model showed that SWAT model can realistically simulate the hydrological processes in the study area. The model was then utilized for land cover change and climate change analyses and their influence on sediment yield. Results showed a significant relationship exists among the changes in the climate regime, land cover distributions and sediment yield. Finally, the study suggested land cover distribution that can potentially mitigate the serious negative effects of climate change to a regional watershed's sediment yield.

  3. How effective are slurry storage, cover or catch crops, woodland creation, controlled trafficking or break-up of compacted layers, and buffer strips as on-farm mitigation measures for delivering an improved water environment?

    Directory of Open Access Journals (Sweden)

    Randall Nicola P


    Full Text Available Abstract Background Agriculture has intensified over the last 50 years resulting in increased usage of fertilizers and agrochemicals, changes in cropping practices, land drainage and increased stocking rates. In Europe, this has resulted in declines in the quality of soils and waters due to increased run off and water pollution. Fifty percent of nitrates in European rivers are derived from agricultural sources in the UK this value is as high as 70%, where agriculture also contributes to approximately 28% of phosphates and 76% of sediments recorded in rivers. Catchments dominated by agricultural land use have increased levels of pesticides and bacterial pathogens. European member states have a policy commitment to tackle water pollution through the Water Framework Directive. An analysis of the effectiveness of water pollution mitigation measures should enable decision makers and delivery agencies to better facilitate catchment planning. The aim of this systematic review is to assess the effectiveness of slurry storage, cover/catch crops, woodland creation, controlled trafficking/break-up of compacted layers and buffer strips, as on farm mitigation measures, for delivering an improved water environment. Methods The systematic review will consist of a searchable systematic map database for all the named interventions. Where possible, quantitative analysis will be used to assess the effectiveness of interventions. Electronic databases, the internet, and organisational websites will be searched, and stakeholders will be contacted for studies that investigate the impact of the on-farm mitigation measures on water quality. All studies found will be assessed for suitability for inclusion in the next stage. Inclusion criteria will be based on subject, intervention, comparator and outcome. The details of included studies will be incorporated into the systematic map database, and studies scored for effectiveness of intervention and study design. Where

  4. Biotechnology System Facility: Risk Mitigation on Mir (United States)

    Gonda, Steve R., III; Galloway, Steve R.


    NASA is working with its international partners to develop space vehicles and facilities that will give researchers the opportunity to conduct scientific investigations in space. As part of this activity, NASA's Biotechnology Cell Science Program (BCSP) at the Johnson Space Center (JSC) is developing a world-class biotechnology laboratory facility for the International Space Station (ISS). This report describes the BCSP, including the role of the BTS. We identify the purpose and objectives of the BTS and a detailed description of BTS facility design and operational concept, BTS facility and experiment-specific hardware, and scientific investigations conducted in the facility. We identify the objectives, methods, and results of risk mitigation investigations of the effects of microgravity and cosmic radiation on the BTS data acquisition and control system. These results may apply to many other space experiments that use commercial, terrestrial-based data acquisition technology. Another focal point is a description of the end-to-end process of integrating and operating biotechnology experiments on a variety of space vehicles. The identification of lessons learned that can be applied to future biotechnology experiments is an overall theme of the report. We include a brief summary of the science results, but this is not the focus of the report. The report provides some discussion on the successful 130-day tissue engineering experiment performed in BTS on Mir and describes a seminal gene array investigation that identified a set of unique genes that are activated in space.

  5. Rolling stones; fast weathering of olivine in shallow seas for cost-effective CO2 capture and mitigation of global warming and ocean acidification

    NARCIS (Netherlands)

    Schuiling, R.D.; Boer, P.L. de


    Human CO2 emissions may drive the Earth into a next greenhouse state. They can be mitigated by accelerating weathering of natural rock under the uptake of CO2. We disprove the paradigm that olivine weathering in nature would be a slow process, and show that it is not needed to mill olivine to very f

  6. Mitigation effects of silicon rich amendments on heavy metal accumulation in rice (Oryza sativa L.) planted on multi-metal contaminated acidic soil (United States)

    The mechanisms of stabilization by silicon-rich amendments of cadmium, zinc, copper and lead in a multi-metal contaminated acidic soil and the mitigation of metal accumulation in rice were investigated in this study. The results from a pot experiment indicated that the application of fly ash (20 and...

  7. Mitigation of methane and nitrous oxide emissions from animal operations: I. A review of enteric methane mitigation options

    NARCIS (Netherlands)

    Hristov, A.N.; Oh, J.; Firkins, J.; Dijkstra, J.; Kebreab, E.; Waghorn, G.; Makkar, H.P.S.; Adesogan, A.T.; Yang, W.; Lee, C.; Gerber, P.J.; Henderson, B.L.; Tricarico, J.M.


    The goal of this review was to analyze published data related to mitigation of enteric methane (CH4) emissions from ruminant animals to document the most effective and sustainable strategies. Increasing forage digestibility and digestible forage intake was one of the major recommended CH4 mitigation

  8. U.S. regional greenhouse gas emissions analysis comparing highly resolved vehicle miles traveled and CO2 emissions: mitigation implications and their effect on atmospheric measurements (United States)

    Mendoza, D. L.; Gurney, K. R.


    Carbon dioxide (CO2) is the most abundant anthropogenic greenhouse gas and projections of fossil fuel energy demand show CO2 concentrations increasing indefinitely into the future. After electricity production, the transportation sector is the second largest CO2 emitting economic sector in the United States, accounting for 32.3% of the total U.S. emissions in 2002. Over 80% of the transport sector is composed of onroad emissions, with the remainder shared by the nonroad, aircraft, railroad, and commercial marine vessel transportation. In order to construct effective mitigation policy for the onroad transportation sector and more accurately predict CO2 emissions for use in transport models and atmospheric measurements, analysis must incorporate the three components that determine the CO2 onroad transport emissions: vehicle fleet composition, average speed of travel, and emissions regulation strategies. Studies to date, however, have either focused on one of these three components, have been only completed at the national scale, or have not explicitly represented CO2 emissions instead relying on the use of vehicle miles traveled (VMT) as an emissions proxy. National-level projections of VMT growth is not sufficient to highlight regional differences in CO2 emissions growth due to the heterogeneity of vehicle fleet and each state’s road network which determines the speed of travel of vehicles. We examine how an analysis based on direct CO2 emissions and an analysis based on VMT differ in terms of their emissions and mitigation implications highlighting potential biases introduced by the VMT-based approach. This analysis is performed at the US state level and results are disaggregated by road and vehicle classification. We utilize the results of the Vulcan fossil fuel CO2 emissions inventory which quantified emissions for the year 2002 across all economic sectors in the US at high resolution. We perform this comparison by fuel type,12 road types, and 12 vehicle types

  9. Report on farm scale eco-efficiency of mitigation and adaption options. D10.3

    DEFF Research Database (Denmark)

    Kristensen, Ib Sillebak; Olesen, Jørgen Eivind; Hutchings, Nicholas John;


    This deliverable collates the information on simulated effects of mitigation and adaptation options at the farm scale in Europe, primarily using the FarmAC model for the mitigation options, and applying semi quantitative modelling for the adaptation options....

  10. Toward to Disaster Mitigation Science (United States)

    Kaneda, Yoshiyuki; Shiraki, Wataru; Tokozakura, Eiji


    Destructive natural disasters such as earthquakes and tsunamis have occurred frequently in the world. For the reduction and mitigation of damages by destructive natural disasters, early detection of natural disasters and speedy and proper evacuations are indispensable. And hardware and software preparations for reduction and mitigation of natural disasters are quite important and significant. Finally, methods on restorations and revivals are necessary after natural disasters. We would like to propose natural disaster mitigation science for early detections, evacuations and restorations against destructive natural disasters. In natural disaster mitigation science, there are lots of research fields such as natural science, engineering, medical treatment, social science and literature/art etc. Especially, natural science, engineering and medical treatment are fundamental research fields for natural disaster mitigation, but social sciences such as sociology, psychology etc. are very important research fields for restorations after natural disasters. We have to progress the natural disaster mitigation science against destructive natural disaster mitigation. in the near future. We will present the details of natural disaster mitigation science.

  11. Melatonin mitigates mitochondrial malfunction. (United States)

    León, Josefa; Acuña-Castroviejo, Darío; Escames, Germane; Tan, Dun-Xian; Reiter, Russel J


    Melatonin, or N-acetyl-5-methoxytryptamine, is a compound derived from tryptophan that is found in all organisms from unicells to vertebrates. This indoleamine may act as a protective agent in disease conditions such as Parkinson's, Alzheimer's, aging, sepsis and other disorders including ischemia/reperfusion. In addition, melatonin has been proposed as a drug for the treatment of cancer. These disorders have in common a dysfunction of the apoptotic program. Thus, while defects which reduce apoptotic processes can exaggerate cancer, neurodegenerative disorders and ischemic conditions are made worse by enhanced apoptosis. The mechanism by which melatonin controls cell death is not entirely known. Recently, mitochondria, which are implicated in the intrinsic pathway of apoptosis, have been identified as a target for melatonin actions. It is known that melatonin scavenges oxygen and nitrogen-based reactants generated in mitochondria. This limits the loss of the intramitochondrial glutathione and lowers mitochondrial protein damage, improving electron transport chain (ETC) activity and reducing mtDNA damage. Melatonin also increases the activity of the complex I and complex IV of the ETC, thereby improving mitochondrial respiration and increasing ATP synthesis under normal and stressful conditions. These effects reflect the ability of melatonin to reduce the harmful reduction in the mitochondrial membrane potential that may trigger mitochondrial transition pore (MTP) opening and the apoptotic cascade. In addition, a reported direct action of melatonin in the control of currents through the MTP opens a new perspective in the understanding of the regulation of apoptotic cell death by the indoleamine.

  12. Experimental study designs to improve the evaluation of road mitigation measures for wildlife

    NARCIS (Netherlands)

    Rytwinski, T.; Van der Ree, van der R.; Cunnington, G.M.; Fahrig, L.; Findlay, C.S.; Houlahan, J.; Jaeger, J.A.G.; Soanes, K.; Grift, van der E.A.


    An experimental approach to road mitigation that maximizes inferential power is essential to ensure that mitigation is both ecologically-effective and cost-effective. Here, we set out the need for and standards of using an experimental approach to road mitigation, in order to improve knowledge of th


    Directory of Open Access Journals (Sweden)

    Sion Hannuna


    Full Text Available Around 52% of the population of India rely on farming for their livelihood which accounts for 17% of India’s GDP. Whilst most farmers are familiar with conventional farming practices, they are often ill positioned to promptly deal with diseases and plant infestations affecting their crops. Current advisory systems tend to be generic and are not tailored to specific plots or farms. This work comprises an agriculture advisory call center similar to a modern call center to provide an agriculture disease mitigation system. The information regarding an individual farm is collected using mobile phones. The image of diseased/infected crop is also captured using mobile phones and is made available to the expert to provide the advisory. To scale the advisory, an attempt is also made to automate the disease recognition process using image processing. Unfortunately, the photos taken will be sensitive to a number of factors including camera type and lighting incident on the scene. Ideally, the images would be processed in such a way as to provide the expert with a visual representation of the affected crops that reflects the true nature of the scene. We describe a framework for standardising the colour of plant images taken using both mobile phones and compact cameras within the context of the advisory system.

  14. Hungry Horse Dam Fisheries Mitigation, 1992-1993 Progress Report.

    Energy Technology Data Exchange (ETDEWEB)

    DosSantos, Joe; Vashro, Jim; Lockard, Larry


    In February of 1900, over forty agency representatives and interested citizens began development of the 1991 Mitigation Plan. This effort culminated in the 1993 Implementation Plan for mitigation of fish losses attributable to the construction and operation of Hungry Horse Dam. The primary purpose of this biennial report is to inform the public of the status of ongoing mitigation activities resulting from those planning efforts. A habitat improvement project is underway to benefit bull trout in Big Creek in the North Fork drainage of the Flathead River and work is planned in Hay Creek, another North Fork tributary. Bull trout redd counts have been expanded and experimental programs involving genetic evaluation, outmigrant monitoring, and hatchery studies have been initiated, Cutthroat mitigation efforts have focused on habitat improvements in Elliott Creek and Taylor`s Outflow and improvements have been followed by imprint plants of hatchery fish and/or eyed eggs in those streams. Rogers Lake west of Kalispell and Lion Lake, near Hungry Horse, were chemically rehabilitated. Cool and warm water fish habitat has been improved in Halfmoon Lake and Echo Lake. Public education and public interest is important to the future success of mitigation activities. As part of the mitigation team`s public awareness responsibility we have worked with numerous volunteer groups, public agencies, and private landowners to stimulate interest and awareness of mitigation activities and the aquatic ecosystem. The purpose of this biennial report is to foster public awareness of, and support for, mitigation activities as we move forward in implementing the Hungry Horse Dam Fisheries Mitigation Implementation Plan.

  15. Composite Materials for Hazard Mitigation of Reactive Metal Hydrides.

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, Joseph William; Cordaro, Joseph Gabriel; Sartor, George B.; Dedrick, Daniel E.; Reeder, Craig L.


    In an attempt to mitigate the hazards associated with storing large quantities of reactive metal hydrides, polymer composite materials were synthesized and tested under simulated usage and accident conditions. The composites were made by polymerizing vinyl monomers using free-radical polymerization chemistry, in the presence of the metal hydride. Composites with vinyl-containing siloxane oligomers were also polymerized with and without added styrene and divinyl benzene. Hydrogen capacity measurements revealed that addition of the polymer to the metal hydride reduced the inherent hydrogen storage capacity of the material. The composites were found to be initially effective at reducing the amount of heat released during oxidation. However, upon cycling the composites, the mitigating behavior was lost. While the polymer composites we investigated have mitigating potential and are physically robust, they undergo a chemical change upon cycling that makes them subsequently ineffective at mitigating heat release upon oxidation of the metal hydride. Acknowledgements The authors would like to thank the following people who participated in this project: Ned Stetson (U.S. Department of Energy) for sponsorship and support of the project. Ken Stewart (Sandia) for building the flow-through calorimeter and cycling test stations. Isidro Ruvalcaba, Jr. (Sandia) for qualitative experiments on the interaction of sodium alanate with water. Terry Johnson (Sandia) for sharing his expertise and knowledge of metal hydrides, and sodium alanate in particular. Marcina Moreno (Sandia) for programmatic assistance. John Khalil (United Technologies Research Corp) for insight into the hazards of reactive metal hydrides and real-world accident scenario experiments. Summary In an attempt to mitigate and/or manage hazards associated with storing bulk quantities of reactive metal hydrides, polymer composite materials (a mixture of a mitigating polymer and a metal hydride) were synthesized and tested

  16. Blue Creek Winter Range : Wildlife Mitigation Project : Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration; United States. Bureau of Indian Affairs; Spokane Tribe of the Spokane Reservation, Washington


    Bonneville Power Administration (BPA) proposes to fund that portion of the Washington Wildlife Agreement pertaining to the Blue Creek Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Spokane Tribe, Upper Columbia United Tribes, and the Bureau of Indian Affairs (BIA). If fully implemented, the proposed action would allow the sponsors to protect and enhance 2,631 habitat units of big game winter range and riparian shrub habitat on 2,185 hectares (5,400 acres) of Spokane Tribal trust lands, and to conduct long term wildlife management activities within the Spokane Indian Reservation project area. This Final Environmental Assessment (EA) examines the potential environmental effects of securing land and conducting wildlife habitat enhancement and long term management activities within the boundaries of the Spokane Indian Reservation. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat adversely affected by the construction of Grand Coulee Dam and its reservoir.

  17. Gas Explosions Mitigation by Ducted Venting



    The mitigation of effects of gas and dust explosions within industrial equipment is effective if venting the combustion products to safe location. The presence of relief duct is however likely to increase the severity of the explosion with respect to equipment vented to open atmosphere, due to secondary explosions occurring in the initial sections of duct, frictional drag and inertia of the gas column, acoustic and Helmholtz oscillations. The weights of these phenomena on explosion e...

  18. 21st century United States emissions mitigation could increase water stress more than the climate change it is mitigating. (United States)

    Hejazi, Mohamad I; Voisin, Nathalie; Liu, Lu; Bramer, Lisa M; Fortin, Daniel C; Hathaway, John E; Huang, Maoyi; Kyle, Page; Leung, L Ruby; Li, Hong-Yi; Liu, Ying; Patel, Pralit L; Pulsipher, Trenton C; Rice, Jennie S; Tesfa, Teklu K; Vernon, Chris R; Zhou, Yuyu


    There is evidence that warming leads to greater evapotranspiration and surface drying, thus contributing to increasing intensity and duration of drought and implying that mitigation would reduce water stresses. However, understanding the overall impact of climate change mitigation on water resources requires accounting for the second part of the equation, i.e., the impact of mitigation-induced changes in water demands from human activities. By using integrated, high-resolution models of human and natural system processes to understand potential synergies and/or constraints within the climate-energy-water nexus, we show that in the United States, over the course of the 21st century and under one set of consistent socioeconomics, the reductions in water stress from slower rates of climate change resulting from emission mitigation are overwhelmed by the increased water stress from the emissions mitigation itself. The finding that the human dimension outpaces the benefits from mitigating climate change is contradictory to the general perception that climate change mitigation improves water conditions. This research shows the potential for unintended and negative consequences of climate change mitigation.

  19. Genistein: A Boon for Mitigating Ischemic Stroke. (United States)

    Nabavi, Seyed Fazel; Daglia, Maria; Tundis, Rosa; Loizzo, Monica Rosa; Sobarzo-Sanchez, Eduardo; Orhan, Ilkay Erdogan; Nabavi, Seyed Mohammad


    In last decades, diet and dietary components have been regarded as important strategies to prevent the development or mitigate numerous chronic diseases, including inflammation, cardiovascular pathologies, cancer, etc. One of the most common dietary components of Asian population is soy. A plethora of research shows the promising effect of soy soy-based foodstuffs and genistein, which is one of the predominant isoflavone compounds, in the prevention and mitigation of stroke. Growing evidence shows that genistein, which is a selective estrogen receptor modulator, mitigates ischemic stroke-induced damages through the modification of oxidative stress and molecular pathways. The promising pharmacological role of genistein is attributed to its ability to suppress nuclear factor (NF)-kappa B and Akt signaling pathway, direct antioxidant action, and targeting estrogen and androgen-mediated molecular pathways which help to mitigate stroke damages and prolong cell survival. In this work, we systematically review the current reports on the therapeutic role of genistein against ischemic stroke and its molecular mechanism of actions.

  20. Investigations into un-mitigated troposphere and multipath effects on kinematic GPS for 3-dimensional monitoring of high rise buiding movements



    Monitoring is a process of observing any changes on a monitored subject. Deformation monitoring is a process which consists of four stages: specification, design, implementation and analysis [Kennie et al., 1990], with the structure being monitored on a daily, hourly or continuous basis for any changes in position, size and shape. With the Global Positioning System (GPS), a 24-hour all weather monitoring system can be established. However, for kinematic GPS, un-mitigated troposphere and multi...

  1. Flood Mitigation of Nyando River Using Duflow Modelling

    Directory of Open Access Journals (Sweden)

    J. Joleha


    Full Text Available Duflow surface water hydrodynamic model has been applied using a case study from Nyando catchment in the western part of Kenya in Africa to simulate various extreme flood behaviours and their retardation levels by using selected structural measures as flood mitigation techniques. The objective of this case study was to establish a design flood recommendable for mitigation, and to identify the most cost effective flood mitigation structure. Various design flows are simulated against the different proposed structures hence, the optimal structure can be recommended when economical, social and environmental constraints are considered in the decision making process. The proposed four flood mitigation structures flood plain extension, embankment (dykes, channel by-pass, and green-storage were simulated for 20-year recurrence interval flood to determine their individual responses in storing excess water. The result shows that building a green-storage is the best and optimal structure for flood mitigation.

  2. Carbon Sequestration to Mitigate Climate Change (United States)

    Sundquist, Eric; Burruss, Robert; Faulkner, Stephen; Gleason, Robert; Harden, Jennifer; Kharaka, Yousif; Tieszen, Larry; Waldrop, Mark


    Human activities, especially the burning of fossil fuels such as coal, oil, and gas, have caused a substantial increase in the concentration of carbon dioxide (CO2) in the atmosphere. This increase in atmospheric CO2 - from about 280 to more than 380 parts per million (ppm) over the last 250 years - is causing measurable global warming. Potential adverse impacts include sea-level rise; increased frequency and intensity of wildfires, floods, droughts, and tropical storms; changes in the amount, timing, and distribution of rain, snow, and runoff; and disturbance of coastal marine and other ecosystems. Rising atmospheric CO2 is also increasing the absorption of CO2 by seawater, causing the ocean to become more acidic, with potentially disruptive effects on marine plankton and coral reefs. Technically and economically feasible strategies are needed to mitigate the consequences of increased atmospheric CO2. The United States needs scientific information to develop ways to reduce human-caused CO2 emissions and to remove CO2 from the atmosphere.

  3. Effective Oral English Activities for ESL Classroom

    Institute of Scientific and Technical Information of China (English)



    Oral English has always been a major problem for Chinese Eng-lish as Second Language (ESL) students. In fact, most Chinese students do not practice oral English very often, while their reading and writing abilities have gained rapid progress. However, language is a system that includes both words and sounds for communicative use, neither of which can be neglected. While there are hundred forms of classroom activities, the usage of most effective o-ral activities has become a serious issue that an ESL teacher should focuses on. The review is based on research results on effective oral ESL activities. The research results on the factors should be considered when selecting/plan-ning oral activities and applying oral activities ESL classes.

  4. Eficácia da intervenção fonoaudiológica para atenuar o envelhecimento facial Effectiveness of speech therapy intervention for mitigating facial aging

    Directory of Open Access Journals (Sweden)

    Yasmin Frazão


    were obtained. Photographic and video documentation on the client's facial features were made. Based on this evaluation and the client's demands, we set out therapeutic targets. In each case, a specific individualized clinical proposal was offered considering the muscular synergy and also the presence or absence of skin flaccidity. Muscular exercises and massages on the face were carried through during twelve 50-minutes sessions. The clients were asked to maintain a customized routine of these procedures at home on a daily basis. RESULTS: after Speech Therapy Treatment, the signs of aging were noticeably mitigated. The results were successful by meeting the clients' expectations, and in addition, all clients reported being satisfied with the treatment. CONCLUSION: Speech Therapy Treatment's effectiveness was noticed through photographic and video documentation as the result of applying an individualized clinical proposal, specific for the orofacial motricity area, through an aesthetic emphasized focus.

  5. Modelling farm vulnerability to flooding: A step toward vulnerability mitigation policies appraisal (United States)

    Brémond, P.; Abrami, G.; Blanc, C.; Grelot, F.


    flood. In the case of farm activities, vulnerability mitigation consists in implementing measures which can be: physical (equipment or electric power system elevation), organizational (emergency or recovery plan) or financial (insurance). These measures aim at decreasing the total damage incurred by farmers in case of flooding. For instance, if equipment is elevated, it will not suffer direct damage such as degradation. As a consequence, equipment will be available to continue production or recovery tasks, thus, avoiding indirect damage such as delays, indebtedness… The effects of these policies on farms, in particular vulnerability mitigation cannot be appraised using current methodologies mainly because they do not consider farm as a whole and focus on direct damage at the land plot scale (loss of yield). Moreover, since vulnerability mitigation policies are quite recent, few examples of implementation exist and no feedback experience can be processed. Meanwhile, decision makers and financial actors require more justification of the efficiency of public fund by economic appraisal of the projects. On the Rhône River, decision makers asked for an economic evaluation of the program of farm vulnerability mitigation they plan to implement. This implies to identify the effects of the measures to mitigate farm vulnerability, and to classify them by comparing their efficacy (avoided damage) and their cost of implementation. In this presentation, we propose and discuss a conceptual model of vulnerability at the farm scale. The modelling, in Unified Modelling Language, enabled to represent the ties between spatial, organizational and temporal dimensions, which are central to understanding of farm vulnerability and resilience to flooding. Through this modelling, we encompass three goals: To improve the comprehension of farm vulnerability and create a framework that allow discussion with experts of different disciplines as well as with local farmers; To identify data which

  6. Adaptive Fuzzy PID Based Control Strategy For 3Phase 4Wire Shunt Active Filter To Mitigate Current Harmonics Of Grid Interconnection Of Renewable Energy Based Distribution System

    Directory of Open Access Journals (Sweden)



    Full Text Available This paper presents a new control strategy for controlling the shunt active power filter to compensate reactive power and to reduce the unwanted harmonics in the grid current. Shunt active filter act as a current source which is connected in parallel with a non-linear load and controlled to produce the required compensating current. The proposed control strategy is based on the fuzzy PID controller which is used for determining the reference compensating currents of the three-phase shunt active power filters. Simulations are carried out using MATLAB/SIMULINK to verify the performance of the proposed controller. The output shows the controller has fast dynamic response high accuracy of tracking DC voltage reference and robust to load parameters variations.

  7. Surface System Dust Mitigation Project (United States)

    National Aeronautics and Space Administration — The proposed effort will perform a detailed examination of dust mitigation and tolerance strategies for connections and mechanisms to be employed on the lunar...

  8. Benchmark of AC and DC Active Power Decoupling Circuits for Second-Order Harmonic Mitigation in Kilowatt-Scale Single-Phase Inverters

    DEFF Research Database (Denmark)

    Qin, Zian; Tang, Yi; Loh, Poh Chiang;


    efficiency and high power density is identified and comprehensively studied, and the commercially available film capacitors, the circuit topologies, and the control strategies adopted for active power decoupling are all taken into account. Then, an adaptive decoupling voltage control method is proposed...

  9. Benchmark of AC and DC active power decoupling circuits for second-order harmonic mitigation in kW-scale single-phase inverters

    DEFF Research Database (Denmark)

    Qin, Zian; Tang, Yi; Loh, Poh Chiang;


    studied, where the commercially available film capacitors, circuit topologies, and control strategies for active power decoupling are all taken into account. Then, an adaptive decoupling voltage control method is proposed to further improve the performance of dc decoupling in terms of efficiency...

  10. The effect of phosphorus binding clay (Phoslock) in mitigating cyanobacterial nuisance: A laboratory study on the effects on water quality variables and plankton

    NARCIS (Netherlands)

    Oosterhout, J.F.X.; Lurling, M.


    This laboratory study examined the lanthanum modified clay Phoslock® for its effectiveness to bind soluble reactive phosphorus (SRP), release of nutrients from this modified clay, its influence on water quality variables (pH, oxygen saturation %, conductivity and turbidity), effects on phytoplankton

  11. Mitigating amphibian chytridiomycosis in nature (United States)

    Garner, Trenton W. J.; Schmidt, Benedikt R.; Martel, An; Pasmans, Frank; Muths, Erin L.; Cunningham, Andrew A.; Weldon, Che; Fisher, Matthew C.; Bosch, Jaime


    Amphibians across the planet face the threat of population decline and extirpation caused by the disease chytridiomycosis. Despite consensus that the fungal pathogens responsible for the disease are conservation issues, strategies to mitigate their impacts in the natural world are, at best, nascent. Reducing risk associated with the movement of amphibians, non-amphibian vectors and other sources of infection remains the first line of defence and a primary objective when mitigating the threat of disease in wildlife. Amphibian-associated chytridiomycete fungi and chytridiomycosis are already widespread, though, and we therefore focus on discussing options for mitigating the threats once disease emergence has occurred in wild amphibian populations. All strategies have shortcomings that need to be overcome before implementation, including stronger efforts towards understanding and addressing ethical and legal considerations. Even if these issues can be dealt with, all currently available approaches, or those under discussion, are unlikely to yield the desired conservation outcome of disease mitigation. The decision process for establishing mitigation strategies requires integrated thinking that assesses disease mitigation options critically and embeds them within more comprehensive strategies for the conservation of amphibian populations, communities and ecosystems.

  12. Hellsgate Winter Range : Wildlife Mitigation Project. Final Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.


    Bonneville Power Administration (BPA) proposes to fund the Hellsgate Winter Range Wildlife Mitigation Project (Project) in a cooperative effort with the Colville Confederated Tribes and the Bureau of Indian Affairs (BIA). The proposed action would allow the sponsors to secure property and conduct wildlife management activities within the boundaries of the Colville Indian Reservation. This Final Environmental Assessment (EA) examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large project area. This area consists of several separated land parcels, of which 2,000 hectares (4,943 acres) have been purchased by BPA and an additional 4,640 hectares (11,466 acres) have been identified by the Colville Confederated Tribes for inclusion in the Project. Four proposed activities (habitat protection, habitat enhancement, operation and maintenance, and monitoring and evaluation) are analyzed. The proposed action is intended to meet the need for mitigation of wildlife and wildlife habitat that was adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs.

  13. Effect of farming practices for greenhouse gas mitigation and subsequent alternative land use on environmental impacts of beef cattle production systems. (United States)

    Nguyen, T T H; Doreau, M; Eugène, M; Corson, M S; Garcia-Launay, F; Chesneau, G; van der Werf, H M G


    This study evaluated effects of farming practice scenarios aiming to reduce greenhouse gas (GHG) emissions and subsequent alternative land use on environmental impacts of a beef cattle production system using the life cycle assessment approach. The baseline scenario includes a standard cow-calf herd with finishing heifers based on grazing, and a standard bull-fattening herd using a diet mainly based on maize silage, corresponding to current farm characteristics and management by beef farmers in France. Alternative scenarios were developed with changes in farming practices. Some scenarios modified grassland management (S1: decreasing mineral N fertiliser on permanent grassland; S2: decreasing grass losses during grazing) or herd management (S3: underfeeding of heifers in winter; S4: fattening female calves instead of being reared at a moderate growth rate; S5: increasing longevity of cows from 7 to 9 years; S6: advancing first calving age from 3 to 2 years). Other scenarios replaced protein sources (S7: partially replacing a protein supplement by lucerne hay for the cow-calf herd; S8: replacing soya bean meal with rapeseed meal for the fattening herd) or increased n-3 fatty acid content using extruded linseed (S9). The combination of compatible scenarios S1, S2, S5, S6 and S8 was also studied (S10). The impacts, such as climate change (CC, not including CO2 emissions/sequestration of land use and land-use change, LULUC), CC/LULUC (including CO2 emissions of LULUC), cumulative energy demand, eutrophication (EP), acidification and land occupation (LO) were expressed per kg of carcass mass and per ha of land occupied. Compared with the baseline, the most promising practice to reduce impacts per kg carcass mass was S10 (all reduced by 13% to 28%), followed by S6 (by 8% to 10%). For other scenarios, impact reduction did not exceed 5%, except for EP (up to 11%) and LO (up to 10%). Effects of changes in farming practices (the scenarios) on environmental impacts varied

  14. Integrated Debris Flow Disaster Mitigation -A Comprehensive Method for Debris Flow Disaster Mitigation

    Institute of Scientific and Technical Information of China (English)


    Integrated disaster mitigation needs interpreting torrent catchment areas as complex landscape systems. The history of valley-evolution shows the influence of climate and vegetation on the valley-evolution. The energy-concept (energy dissipation concept including the idea of the energy-line) is used for a simple explanation of debris flow. Examples of heavy debris flow disasters in controlled torrents in the Alps and Pyrenees give hints, which expanding the time scale can show that side-effects restrict or counteract the mitigation measures. A pallet of different mitigation measures to avoid or to reduce some of the side-effects is shown. The comprehensive method of disaster mitigation also includes the effect of vegetation. The pallet includes: avoiding hazards (hazard mapping, warning and alarming), appropriate land use and avoiding disaster-enhancing measures in the landscape and technical measures, which take into account their side-effects. The energy line is used as simple design theory. The Jiu-Jitsu Principle is explained too. With this comprehensive method a more sustainable reduction of disasters seems possible.

  15. Insider Threat Mitigation Workshop Instructional Materials

    Energy Technology Data Exchange (ETDEWEB)

    Gibbs, Philip [Brookhaven National Lab. (BNL), Upton, NY (United States); Larsen, Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); O' Brien, Mike [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rodriquez, Jose [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt theft of nuclear materials. This report is a compilation of workshop materials consisting of lectures on technical and administrative measures used in Physical Protection (PP) and Material Control and Accounting (MC&A) and methods for analyzing their effectiveness against a postulated insider threat.

  16. Framework for Analysis of Mitigation in Courts (United States)


    examinations in six Swedish (Andenaes, 1968; Inger, 1986) and five Bulgarian (Terziev, 1987) court trials. Altogether the bilingual corpus consists of 46 000...not be mitigated because they do not have unwelcome effect, which is problematic to apply especially in intercultural communication perspective...Acknowledgements I express my gratitude to Jens Allwood and The Swedish Foundation of International Cooperation in Research and Higher Education (STINT) for

  17. Earthquake Response Mitigation of RC Building Using Friction Pendulum System


    Sudarshan B. Sanap; Pradip D. Jadhao; S. M. Dumne


    Earthquake hazard mitigation is very sensitive issue now a day’s therefore researchers are struggling for optimum solution since last few decades. Base isolation technique is one of the effective techniques which give better results seismic hazard mitigation under earthquake excitation particularly in building structures, bridges and water tanks etc. Base isolation reduces not only the effects of earthquake acceleration to be transmitted to the structures, but also protects the content of ...

  18. 2010 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report

    Energy Technology Data Exchange (ETDEWEB)

    C. T. Lindsey, A. L. Johnson


    This report documents eh status of revegetation projects and natural resources mitigation efforts conducted for remediated waste sites and other activities associated with CERLA cleanup of National Priorities List waste sites at Hanford. This report contains vegetation monitoring data that were collected in the spring and summer of 2010 from the River Corridor Closure Contract’s revegetation and mitigation areas on the Hanford Site.

  19. 2011 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report

    Energy Technology Data Exchange (ETDEWEB)

    West, W. J.; Lucas, J. G.; Gano, K. A.


    This report documents the status of revegetation projects and natural resources mitigation efforts conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 cleanup of National Priorities List waste sites at Hanford. This report contains the vegetation monitoring data that was collected in the spring and summer of 2011 from the River Corridor Closure Contractor’s revegetation and mitigation areas on the Hanford Site.

  20. Ocean-Based Alkalinity Enhancement: Mitigation Potential, Side Effects and the Fate of Added Alkalinity Assessed in an Earth System Model (United States)

    Gonzalez, M. F.; Ilyina, T.


    Artificial ocean alkalinization (AOA) has been proposed as a mean to mitigate climate change and ocean acidification. Whilst the mitigation potential of this geo-engineering technology may sound promising, it poses environmental risks. Within the Priority Program "Climate Engineering" of the German Science Foundation (DFG), we investigate the mitigation potential of AOA to reduce atmospheric CO2 and counteract the consequences of ocean acidification. We are particularly interested in the residence time of the added alkalinity at the ocean surface because it must stay in the upper ocean in order to increase the oceanic CO2 uptake. The mitigation potential, risks and the unintended consequences of this geo-engineering method are also exhaustively studied. These questions are tackled through the analysis of different alkalinity enhancement scenarios in the state-of-the-art Earth system model of the Max Planck Institute for Meteorology (MPI-ESM) in a configuration based on the fifth phase of the Coupled Model Intercomparison Project (CMIP5). Model scenarios are designed so that AOA is performed to keep the atmospheric CO2 concentrations similar to values of the stabilization scenario RCP4.5, while fossil fuel CO2 emissions follow the pathway of the high-CO2 scenario RCP8.5. Alkalinity is added globally into the upper 12 meters of the ocean in different seasons and years. We found that on the time scale of relevance (i.e. from years to decades), season and location are key aspects to take into account in the implementation of AOA. This is because of inhomogeneous vertical mixing of added alkalinity due to the mixed layer depth which is established by the season. We also show that the rate of addition greatly determines impact and outcome of this geo-engineering method. Changes driven by the implementation of this method in the ocean biogeochemistry are also discussed. For instance, the associated changes in the carbon cycle, marine oxygen levels, saturation state of

  1. Accessing international financing for climate change mitigation - A guidebook for developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Limaye, D.R.; Zhu, X.


    This guidebook has been prepared by the UNEP Risoe Centre (URC) as part of its Technology Needs Assessment (TNA) project. The TNA project assists developing countries to identify national mitigation and adaptation technology priorities and to develop Technology Action Plans (TAPs) for mitigation of greenhouse gas (GHG) emissions and climate change adaptation. This guidebook provides information to help TNA countries better identify and access financial resources for the mitigation activities included in their national TAPs. This guidebook covers both mitigation 'projects' (such as a wind farm or a solar PV generation facility) and 'programmes' (such as a credit line for financing energy efficiency projects in small and medium-sized enterprises (SMEs), or bulk procurement and distribution of compact fluorescent lamps to households). The primary emphasis is on multilateral and bilateral sources of financing but the guidebook also includes an overview of private funding sources and public-private partnerships (PPPs). This guidebook only covers international financing for mitigation actions in developing countries. For example, EU funding for EU member countries and Chinese funding for mitigation in China are not covered in this guidebook. However, the EU funding for mitigation in developing countries and Chinese funding supporting mitigation in other developing countries are included. Special funds established in some developing countries by pooling financing support from developed countries are also covered in this guidebook. Information on the financing sources was compiled in a standard format and reviewed and analysed to categorise the financing sources. For the multilateral and bilateral financing sources, the available information was used to define their major characteristics (such as geographic coverage, technology/sector focus, funding sources, financing objectives, financing mechanisms, and management and governance). In addition, the

  2. Mitigating greenhouse gas emissions with agricultural land management changes: What practices hold the best potential? (United States)

    Eagle, A. J.; Olander, L.; Rice, C. W.; Haugen-Kozyra, K.; Henry, L. R.; Baker, J. S.; Jackson, R. B.


    Agricultural land management practices within the United States have significant potential to mitigate greenhouse gases (GHGs) in voluntary market or regulatory contexts - by sequestering soil carbon or reducing N2O or CH4 emissions. Before these practices can be utilized in active protocols or within a regulatory or farm bill framework, we need confidence in our ability to determine their impact on GHG emissions. We develop a side-by-side comparison of mitigation potential and implementation readiness for agricultural GHG mitigation practices, with an extensive literature review. We also consider scientific certainty, environmental and social co-effects, economic factors, regional specificity, and possible implementation barriers. Biophysical GHG mitigation potential from agricultural land management activities could reach more than 500 Mt CO2e/yr in the U.S. (7.1% of annual emissions). Up to 75% of the total potential comes from soil C sequestration. Economic potential is lower, given necessary resources to incentivize on-farm adaptations, but lower cost activities such as no-till, fertilizer N management, and cover crops show promise for near-term implementation in certain regions. Scientific uncertainty or the need for more research limit no-till and rice water management in some areas; and technical or other barriers need to be addressed before biochar, advanced crop breeding, and agroforestry can be widely embraced for GHG mitigation. Significant gaps in the current research and knowledge base exist with respect to interactions between tillage and N2O emissions, and with fertilizer application timing impacts on N2O emissions.


    Energy Technology Data Exchange (ETDEWEB)

    J.R. Paterek; G. Husmillo


    The overall program objective is to develop and evaluate environmental benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is one or more environmental benign, a.k.a. ''green'' products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter were monitoring the development of Desulfovibrio species biofilm using the continuous flow cell system, evaluation of pepper compounds by microtiter plate assay for mitigating and inhibiting biofilm formation, and testing the effective concentrations to verify the extent of corrosion on metal coupons. Biofilm formation of Desulfovibrio vulgaris and D. desulfuricans was monitored and documented over a 7-day period. The use of a continuous flow cell system proved to be efficient and non-destructive in studying biofilm growth. Live/Dead BacLight was an efficient stain to determine cell viability. The extracts showed 9-25% biofilm formation inhibition against the two organisms, and 18-19% activity in detaching the already formed biofilm. Preliminary data were obtained on the extent of corrosion of metal coupons when treated with pepper extracts as against the untreated ones. Confirmatory tests are underway. A presentation was prepared and give at the US DOE NETL meeting on gas and petroleum infrastructure. The presentation is include as an addition to this report.

  4. Eight years of Conservation Agriculture-based cropping systems research in Eastern Africa to conserve soil and water and mitigate effects of climate change (United States)

    Araya, Tesfay; Nyssen, Jan; Govaerts, Bram; Lanckriet, Sil; Baudron, Frédéric; Deckers, Jozef; Cornelis, Wim


    at large scale in a 180 ha catchment, would reduce to 581 t y-1, instead of 1109 t y-1 under the current farmer practice. Using NASA/GISS Model II precipitation projections of IPCC scenario A1FI, CA is estimated to reduce soil loss and runoff and mitigate the effect of increased rainfall due to climate change. For smallholder farmers in semi-arid agro-ecosystems, CA-based systems constitute a field rainwater and soil conservation improvement strategy that enhances crop and economic productivity and reduces siltation of reservoirs, especially under changing climate. The reduction in draught power requirement would enable a reduction in oxen density and crop residue demand for livestock feed, which would encourage smallholder farmers to increase biomass return to the soil. Adoption of CA-based systems in the study area requires further work to improve smallholder farmers' awareness on benefits, to guarantee high standards during implementation and to design appropriate weed management strategies.

  5. [Effect of exogenous sucrose on growth and active ingredient content of licorice seedlings under salt stress conditions]. (United States)

    Liu, Fu-zhi; Yang, Jun


    Licorice seedlings were taken as experimental materials, an experiment was conducted to study the effects of exogenous sucrose on growth and active ingredient content of licorice seedlings under NaCl stress conditions. The results of this study showed that under salt stress conditions, after adding a certain concentration of exogenous sucrose, the licorice seedlings day of relative growth rate was increasing, and this stress can be a significant weakening effect, indicating that exogenous sucrose salt stress-relieving effect. The total flavonoids and phenylalanine ammonia lyase (PAL) activity were significantly increased, the exogenous sucrose can mitigated the seedling roots under salt stress, the licorice flavonoid content in the enhanced growth was largely due to the activity of PAL an increased, when the concentration of exogenous sucrose wae 10 mmol x L(-1), PAL activity reaching a maximum, when the concentration of exogenous sucrose was 15 mmol x L(-1), PAL activity turned into a downward trend, the results indicating that this mitigation has concentration effect. After applying different concentrations of exogenous sugar, the contents of liquiritin changes with the change of flavonoids content was similar. After applying different concentrations of exogenous sucrose, the content of licorice acid under salt stress was higher than the levels were not reached during salt stress, the impact of exogenous sucrose concentration gradient of licorice acid accumulation was not obvious.

  6. Spreading depolarization in the brain of Drosophila is induced by inhibition of the Na+/K+-ATPase and mitigated by a decrease in activity of protein kinase G. (United States)

    Spong, Kristin E; Rodríguez, Esteban C; Robertson, R Meldrum


    Spreading depolarization (SD) is characterized by a massive redistribution of ions accompanied by an arrest in electrical activity that slowly propagates through neural tissue. It has been implicated in numerous human pathologies, including migraine, stroke, and traumatic brain injury, and thus the elucidation of control mechanisms underlying the phenomenon could have many health benefits. Here, we demonstrate the occurrence of SD in the brain of Drosophila melanogaster, providing a model system, whereby cellular mechanisms can be dissected using molecular genetic approaches. Propagating waves of SD were reliably induced by disrupting the extracellular potassium concentration ([K(+)]o), either directly or by inhibition of the Na(+)/K(+)-ATPase with ouabain. The disturbance was monitored by recording the characteristic surges in [K(+)]o using K(+)-sensitive microelectrodes or by monitoring brain activity by measuring direct current potential. With the use of wild-type flies, we show that young adults are more resistant to SD compared with older adults, evidenced by shorter bouts of SD activity and attenuated [K(+)]o disturbances. Furthermore, we show that the susceptibility to SD differs between wild-type flies and w1118 mutants, demonstrating that our ouabain model is influenced by genetic strain. Lastly, flies with low levels of protein kinase G (PKG) had increased latencies to onset of both ouabain-induced SD and anoxic depolarization compared with flies with higher levels. Our findings implicate the PKG pathway as a modulator of SD in the fly brain, and given the conserved nature of the signaling pathway, it could likely play a similar role during SD in the mammalian central nervous system.

  7. Novel CD28 antagonist mPEG PV1-Fab’ mitigates experimental autoimmune uveitis by suppressing CD4+ T lymphocyte activation and IFN-γ production (United States)

    Papotto, Pedro Henrique; Marengo, Eliana Blini; Sardinha, Luiz Roberto; Carvalho, Karina Inácio; de Carvalho, Ana Eduarda Zulim; Castillo-Mendez, Sheyla; Jank, Carina Calixto; Vanhove, Bernard; Goldberg, Anna Carla; Rizzo, Luiz Vicente


    Autoimmune Uveitis is an important chronic inflammatory disease and a leading cause of impaired vision and blindness. This ocular autoimmune disorder is mainly mediated by T CD4+ lymphocytes poising a TH1 phenotype. Costimulatory molecules are known to play an important role on T cell activation and therefore represent interesting therapeutical targets for autoimmune disorders. CD28 is the prototypical costimulatory molecule for T lymphocytes, and plays a crucial role in the initiation, and maintenance of immune responses. However, previous attempts to use this molecule in clinical practice achieved no success. Thus, we evaluated the efficacy of mPEG PV1-Fab’ (PV1), a novel selective CD28 antagonist monovalent Fab fragment in the treatment of Experimental Autoimmune Uveitis (EAU). Here, we showed that PV1 treatment decreases both average disease score and incidence of EAU. A decrease in the activation profile of both T CD4+ and T CD8+ eye-infiltrating lymphocytes was evidenced. In the periphery, T CD4+ cells from PV1-treated mice also showed a decrease in their activation status, with reduced expression of CD69, CD25, and PD-1 molecules. This suppression was not dependent on Treg cells, as both their frequency and absolute number were lower in PV1-treated mice. In addition, frequency of CD4+IFN-γ+ T cells was significantly lower in PV1-treated group, but not of IL-17-producing T cells. Moreover, after specific restimulation, PV1 blockade selectively blocked IFN-γ production by CD4+ lymphocytes Taken together, our data suggest that mPEG PV1-Fab’ acts mainly on IFN-γ-producing CD4+ T cells and emphasize that this specific CD28 blockade strategy is a potential specific and alternative tool for the treatment of autoimmune disorders in the eye. PMID:28248972

  8. Evidence-based effectiveness of vaccination against Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in feedlot cattle for mitigating the incidence and effect of bovine respiratory disease complex. (United States)

    Larson, R L; Step, D L


    Bovine respiratory disease complex is the leading cause of morbidity and mortality in feedlot cattle. A number of vaccines against bacterial respiratory pathogens are commercially available and researchers have studied their impact on morbidity, mortality, and other disease outcome measures in feedlot cattle. A systematic review will provide veterinarians with a rigorous and transparent evaluation of the published literature to estimate the extent of vaccine effect. Unfortunately, the published body of evidence does not provide a consistent estimate of the direction and magnitude of effectiveness in feedlot cattle vaccination against Mannheimia haemolytica, Pasteurella multocida, or Histophilus somni.

  9. Can increased organic consumption mitigate climate changes?

    DEFF Research Database (Denmark)

    Heerwagen, Lennart Ravn; Andersen, Laura Mørch; Christensen, Tove


    correlation between increasing organic budget shares and decreasing meat budget shares is found. People include food-related behaviour such as the purchase of organic food and reduced meat consumption as ways to mitigate climate change. However, other behavioural modifications such as reduction of car usage...... and household heating are perceived as more important strategies. Research limitations/implications – Other food-related mitigation strategies could be investigated. The climate effect of different diets – and how to motivate consumers to pursue them – could be investigated. Individual as opposed to household...... the climate-friendliness of consumption using consumption of organic food as a case. The authors link stated concerns for climate changes with actual food-related behaviour....

  10. Drag sails for space debris mitigation (United States)

    Visagie, Lourens; Lappas, Vaios; Erb, Sven


    The prudence for satellites to have a mitigation or deorbiting strategy has been brought about by the ever increasing amount of debris in Earth orbit. Drag augmentation is a potentially passive method for de-orbiting in LEO but its collision risk mitigation efficiency is sometimes underestimated by not taking all the relevant factors into account. This paper shows that using drag augmentation from a deployable drag-sail to de-orbit a satellite in LEO will lead to a reduction in collision risk. In order to support this finding, the models that are needed in order to evaluate the collision risk of a decaying object under drag conditions are presented. A comparison is performed between the simpler Area-Time-Product (ATP) and more precise collision risk analysis, and the effects that are overlooked in the simple ATP calculation are explained.

  11. Trientine Reduces BACE1 Activity and Mitigates Amyloidosis via the AGE/RAGE/NF-κB Pathway in a Transgenic Mouse Model of Alzheimer's Disease


    Wang, Chun-yan; Xie, Jing-Wei; Xu, Ye; WANG Tao; Cai, Jian-Hui; Wang,Xu; Zhao, Bao-Lu; AN Li; Wang, Zhan-You


    Aims: There is mounting evidence that the transition metal copper may play an important role in the pathophysiology of Alzheimer's disease (AD). Triethylene tetramine dihydrochloride (trientine), a CuII-selective chelator, is a commonly used treatment for Wilson's disease to decrease accumulated copper, and thereby decreases oxidative stress. In the present study, we evaluated the effects of a 3-month treatment course of trientine (Trien) on amyloidosis in 7-month-old β-amyloid (Aβ) precursor...

  12. Study of the activity of quaternary ammonium compounds in the mitigation of biofouling in heat exchangers-condensers cooled by seawater. (United States)

    Trueba, Alfredo; Otero, Félix M; González, José A; Vega, Luis M; García, Sergio


    The effectiveness of two quaternary ammonium compounds (QACs) (non-oxidising biocides) to reduce the growth of biofilm adhering to the tubes of a heat exchanger-condenser cooled by seawater was evaluated. Their effectiveness was compared to that of a conventional oxidising biocide (sodium hypochlorite [NaOCl]) under the same testing conditions. Each biocide was applied intermittently (6 h on, 6 h off) in a first shock stage (1.5 ppm over 8 days) and a second stabilising stage (0.5 ppm over 20 days). The results showed that the antifouling effectiveness of the first of the QACs (fifth generation) was comparable to that shown by the oxidising power of NaOCl. Although the reaction time was longer than that of NaOCl, both the compounds removed the biofilm, and the tube was practically restored to its clean condition. Treatment with the second of the QACs (fourth generation) allowed for the stabilisation of biofilm growth, but not for its removal. Ecotoxicology studies classified the QACs as environmentally harmless under the testing conditions.

  13. Advance in Evaluation the Effect of Carbon Sequestration Strategies on Greenhouse Gases Mitigation in Agriculture%农田固碳措施对温室气体减排影响的研究进展

    Institute of Scientific and Technical Information of China (English)

    石岳峰; 吴文良; 孟凡乔; 王大鹏; 张志华


    Agricultural field is an important source for three primary greenhouse gases (GHGs), including CO2, CH4 and N2O. Unreasonable agricultural managements increase CHGs and decrease the effect of soil carbon sequestration. Agricultural activities generate the largest share, 58% of the world's anthropogenic non-carbon dioxide (non-CO2) emission, and make up roughly 14% of all anthropogenic CHG emissions. And soil carbon pool is the most active carbon pools in ecosystems. In addition, soil carbon pool could be a source or sink of GHGs. Many researches indicated that the optimized agricultural practices play an important role not only in mitigating GHGs emission and increasing reserves of soil carbon pool, but also in improving soil quality. Both temperature, precipitation, vegetation types and application of fertilizers/straws, tillage and irrigation management practices can exert significant effects on carbon sequestration in soil. This paper analyzes the practices of conservation tillage/ no tillage, residue return, nitrogen fertilizer and water managements, agronomy managements and land-use change and proposes the reasonable ways on increasing carbon sequestration potential and mitigation GHGs mission. The stable or increasing of soil carbon sequestration plays an important role in guarantying global food security and mitigation climate change. Many of researches about soil carbon sequestration and greenhouse gas emissions are not system or limited to short-term studies in China, which increases the uncertainly for the correct evaluation of carbon sequestration management practices on greenhouse gas emissions.%农田是CO2,CH4和N2O三种温室气体的重要排放源,在全球范围内农业生产活动贡献了约14%的人为温室气体排放量,以及58%的人为非CO2排放,不合理的农田管理措施强化了农田温室气体排放源特征,弱化了农田固碳作用.土壤碳库作为地球生态系统中最活跃的碳库之一,同时也是温室气


    Arsenic effects on telomere and telomerase activity. T-C. Zhang, M. T. Schmitt, J. Mo, J. L. Mumford, National Research Council and U.S Environmental Protection Agency, NHEERL, Research Triangle Park, NC 27711Arsenic is a known carcinogen and also an anticancer agent for acut...

  15. Mitigation for the Construction and Operation of Libby Dam, 2003-2004 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Dunnigan, James; DeShazer, Jay; Garrow, Larry (Montana Department of Fish, Wildlife and Parks, Libby, MT)


    ''Mitigation for the Construction and Operation of Libby Dam'' is part of the Northwest Power and Conservation Council's (NPCC) resident fish and wildlife program. The program was mandated by the Northwest Planning Act of 1980, and is responsible for mitigating for damages to fish and wildlife caused by hydroelectric development in the Columbia River Basin. The objective of Phase I of the project (1983 through 1987) was to maintain or enhance the Libby Reservoir fishery by quantifying seasonal water levels and developing ecologically sound operational guidelines. The objective of Phase II of the project (1988 through 1996) was to determine the biological effects of reservoir operations combined with biotic changes associated with an aging reservoir. The objectives of Phase III of the project (1996 through present) are to implement habitat enhancement measures to mitigate for dam effects, to provide data for implementation of operational strategies that benefit resident fish, monitor reservoir and river conditions, and monitor mitigation projects for effectiveness. This project completes urgent and high priority mitigation actions as directed by the Kootenai Subbasin Plan. Montana FWP uses a combination of diverse techniques to collect a variety of physical and biological data within the Kootenai River Basin. These data serve several purposes including: the development and refinement of models used in management of water resources and operation of Libby Dam; investigations into the limiting factors of native fish populations, gathering basic life history information, tracking trends in endangered, threatened species, and the assessment of restoration or management activities intended to restore native fishes and their habitats.

  16. Mitigation for the Construction and Operation of Libby Dam, 2004-2005 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Dunnigan, James; DeShazer, Jay; Garrow, Larry (Montana Department of Fish, Wildlife and Parks, Libby, MT)


    ''Mitigation for the Construction and Operation of Libby Dam'' is part of the Northwest Power and Conservation Council's (NPCC) resident fish and wildlife program. The program was mandated by the Northwest Planning Act of 1980, and is responsible for mitigating damages to fish and wildlife caused by hydroelectric development in the Columbia River Basin. The objective of Phase I of the project (1983 through 1987) was to maintain or enhance the Libby Reservoir fishery by quantifying seasonal water levels and developing ecologically sound operational guidelines. The objective of Phase II of the project (1988 through 1996) was to determine the biological effects of reservoir operations combined with biotic changes associated with an aging reservoir. The objectives of Phase III of the project (1996 through present) are to implement habitat enhancement measures to mitigate for dam effects, to provide data for implementation of operational strategies that benefit resident fish, monitor reservoir and river conditions, and monitor mitigation projects for effectiveness. This project completes urgent and high priority mitigation actions as directed by the Kootenai Subbasin Plan. Montana Fish, Wildlife & Parks (MFWP) uses a combination of techniques to collect physical and biological data within the Kootenai River Basin. These data serve several purposes including: the development and refinement of models used in management of water resources and operation of Libby Dam; investigations into the limiting factors of native fish populations, gathering basic life history information, tracking trends in endangered and threatened species, and the assessment of restoration or management activities designed to restore native fishes and their habitats.

  17. Effect of Crime Prevention through Environmental Design (CPTED Measures on Active Living and Fear of Crime

    Directory of Open Access Journals (Sweden)

    Jae Seung Lee


    Full Text Available Crime prevention through environmental design (CPTED has become a popular urban planning approach to preventing crime and mitigating fear of crime through the improvement of physical neighborhood environments. CPTED is widely used to improve deteriorated neighborhoods that suffer from crime. However, few studies have empirically examined the complex relationships among CPTED, fear of crime, and active living. Our study, therefore, investigated the effects of CPTED measures on walking frequency and fear of crime, analyzing behavioral data of residents living in participatory neighborhood regeneration areas and matched neighborhoods. We analyzed survey data from 12 neighborhoods that implemented CPTED approaches and 12 matched neighborhoods in Seoul, Korea, using structural equation modeling, which could consistently estimate complex direct and indirect relationships between a latent variable (fear of crime and observable variables (CPTED measures and walking frequency. We designed the survey instrument as a smartphone app. Participants were recruited from 102 locations within the 24 selected neighborhoods; in total, 623 individuals returned surveys. The results revealed that sufficient closed-circuit television, street lighting, and maintenance played a significant role in mitigating fear of crime. This study has implications for planning and policy issues related to CPTED, mental health, and active living.

  18. Hellsgate Winter Range : Wildlife Mitigation Project. Preliminary Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.


    The Bonneville Power Administration proposes funding the Hellsgate Winter Range Wildlife Mitigation Project in cooperation with the Colville Convederated Tribes and Bureau of Indian Affairs. This Preliminary Environmental Assessment examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large project area. The Propose action is intended to meet the need for mitigation of wildlife and wild life habitat that was adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs.

  19. Mitigation of earthquake hazards using seismic base isolation systems

    Energy Technology Data Exchange (ETDEWEB)

    Wang, C.Y.


    This paper deals with mitigation of earthquake hazards using seismic base-isolation systems. A numerical algorithm is described for system response analysis of isolated structures with laminated elastomer bearings. The focus of this paper is on the adaptation of a nonlinear constitutive equation for the isolation bearing, and the treatment of foundation embedment for the soil-structure-interaction analysis. Sample problems are presented to illustrate the mitigating effect of using base-isolation systems.

  20. Avoided deforestation as a greenhouse gas mitigation tool: economic issues. (United States)

    Sohngen, Brent; Beach, Robert H; Andrasko, Kenneth


    Tropical deforestation is a significant contributor to accumulation of greenhouse gases (GHGs) in the atmosphere. GHG emissions from deforestation in the tropics were in the range of 1 to 2 Pg C yr(-1) for the 1990s, which is equivalent to as much as 25% of global anthropogenic GHG emissions. While there is growing interest in providing incentives to avoid deforestation and consequently reduce net carbon emissions, there is limited information available on the potential costs of these activities. This paper uses a global forestry and land use model to analyze the potential marginal costs of reducing net carbon emissions by avoiding deforestation in tropical countries. Our estimates suggest that about 0.1 Pg C yr(-1) of emissions reductions could be obtained over the next 30 to 50 yr for $5 per Mg C, and about 1.6 Pg C yr(-1) could be obtained over the same time frame for $100 per Mg C. In addition, the effects of carbon incentives on land use could be substantial. Relative to projected baseline conditions, we find that there would be around 3 million additional hectares (ha) of forestland in 2055 at $5 per Mg C and 422 million ha at $100 per Mg C. Estimates of reductions in area deforested, GHG mitigation potential, and annual land rental payments required are presented, all of which vary by region, carbon price paid, and time frame of mitigation.

  1. Effects of rippled fields due to ferritic inserts and ELM mitigation coils on energetic ion losses in a 15 MA inductive scenario in ITER (United States)

    Shinohara, K.; Tani, K.; Oikawa, T.; Putvinski, S.; Schaffer, M.; Loarte, A.


    The energetic ion loss has been assessed using the F3D-OFMC code for a 15 MA inductive scenario with Q = 10 and the latest information on the first wall geometry, the implementation of ferritic inserts (FI) and the ELM mitigation/control coils. Alpha particles and NB ions generated by the neutral beam injectors with the injection energy of 1 MeV are well confined and the heat load on the first wall is negligibly small and allowable for the magnetic background by the toroidal field coils and FI. However, an increase in the loss of these energetic ions is observed when the magnetic field by the ELM coils is applied. The increase in the loss fraction is larger for NB ions than for alpha particles under the ELM coil field. The origin of the expelled NB ions is dominantly trapped ions generated in the peripheral region due to a high-density plasma of the 15 MA scenario.

  2. Horizontal shaking table tests and analysis on structures with multi-dimensional earthquake isolation and mitigation devices

    Institute of Scientific and Technical Information of China (English)


    The viscoelastic multi-dimensional earthquake isolation and mitigation device is a new kind of passive control device, which has both earthquake isolation and earthquake mitigation abilities. In order to quantify the horizontal earthquake isolation and mitigation effect of this device on structures, shaking table tests on structures with and without the devices and the corresponding analysis on earthquake isolation and mitigation properties are carried out. It can be shown from the experimental and analytical results that the device has both earthquake isolation and earthquake mitigation effects on structures in horizontal direction, and its horizontal earthquake mitigation coefficients can be referred to those of the rubber bearing earthquake isolation structure.

  3. Evaporation mitigation by floating modular devices (United States)

    Hassan, M. M.; Peirson, W. L.


    Prolonged periods of drought and consequent evaporation from open water bodies in arid parts of Australia continue to be a threat to water availability for agricultural production. Over many parts of Australia, the annual average evaporation exceeds the annual precipitation by more than 5 times. Given its significance, it is surprising that no evaporation mitigation technique has gained widespread adoption to date. High capital and maintenance costs of manufactured products are a significant barrier to implementation. The use of directly recycled clean plastic containers as floating modular devices to mitigate evaporation has been investigated for the first time. A six-month trial at an arid zone site in Australia of this potential cost effective solution has been undertaken. The experiment was performed using clean conventional drinking water bottles as floating modules on the open water surface of 240-L tanks with three varying degrees of covering (nil, 34% and 68%). A systematic reduction in evaporation is demonstrated during the whole study period that is approximately linearly proportional to the covered surface. These results provide a potential foundation for robust evaporation mitigation with the prospect of implementing a cost-optimal design.

  4. A New Strategy for Mitigating Climate Change

    Energy Technology Data Exchange (ETDEWEB)

    Kaya, Y.; Akimoto, K./ Oda, J.


    This paper proposes a new strategy for mitigating climate change, both in short term and in long term. The basic character of the strategy is action oriented with multi-country collaboration, while the Framework Convention on Climate Change (FCCC) and Kyoto protocol is numerical target oriented within United Nation Framework. The introductory part of the paper briefly describes deficits of FCCC and Kyoto protocol and the needs of a different strategy for mitigating climate change. Then the short term strategy is focused on energy conservation and its effectiveness for mitigating climate change is illustrated by estimating the potential of reducing CO{sub 2} emission when intense collaboration is achieved for distributing main energy conservation measures in power generation and key industries among Asia Pacific Partnership countries. The long term strategy is developing novel types of renewables among countries. Geoheat and space solar power systems (SSPS) are candidates which may be developed among major developed countries. Necessity of international collaboration is stressed for R and D of these candidate renewables. (auth)

  5. The "Mozart effect" on epileptiform activity. (United States)

    Hughes, J R; Daaboul, Y; Fino, J J; Shaw, G L


    The "Mozart Effect," using the Piano Sonata in D Major (K.448), was examined in patients with seizures. In 23 of 29 instances significant decreases in epileptiform activity were noted from patients even in coma, with status epilepticus or with periodic lateralized epileptiform discharges (PLEDs). The effect may be immediate or require 40-300 sec to manifest itself. The change in the amount of ictal activity in one patient in coma was from 62% before the music to 21% during Mozart. Amplitudes of these discharges also have often decreased. Examples of PLEDs on both temporal areas are shown in which the effect was only on the left temporal area but in other patients only on the right temporal area. Brain maps during the music showed theta and alpha activity decreased on the central areas, while delta waves increased on the frontal midline area. The basis of this effect is likely that the superorganization of the cerebral cortex with its highly structured radial columns seen throughout both hemispheres may resonate with the superior architecture of Mozart's music.

  6. Effects of agricultural management on productivity, soil quality and climate change mitigation - evaluations within the EU Project (FP 7) CATCH-C (United States)

    Spiegel, Heide; Schlatter, Norman; Haslmayr, Hans-Peter; Baumgarten, Andreas; ten Berge, Hein


    Soils are the main basis for the production of food and feed. Furthermore, the production of biomass for energy and material use is becoming increasingly important. Goals for an optimal management of agricultural soils are, on the one hand, the maintenance or improvement of soil quality and, on the other hand, high productivity and climate change mitigation (reduction of GHG emissions and C sequestration). Thus, the EU project CATCH-C aims to evaluate current management practices concerning these three goals based on indicators derived from long-term field experiments of the project partners and from literature data. A maximum of 72 indicators for productivity, soil quality and the potential for carbon storage in the soil and the reduction of greenhouse gas emissions were selected by the project partners. As indicators for productivity, crop yields are determined in almost all field trials. The content of soil organic carbon (SOC) is an indicator for chemical, physical and biological soil quality and was analysed in the topsoil in all field trials. Less data exist for SOC contents in the subsoil. An important physical soil quality indicator is the bulk density, however, it is not determined in all field trials of the project partners. Therefore, information on SOC stocks, with relevance to carbon storage and climate change mitigation, is not available in all field experiments. Other physical indicators, such as penetration resistance, runoff coefficient and soil losses are evaluated. Essential biological indicators are microbial biomass and the number and weight of earthworms, which have been tested in several field trials. The evaluation of all these indicators will help to select "best management practices" and to address trade-offs and synergies for all indicators under consideration of major European farm type zones. CATCH-C is funded within the 7th Framework Programme for Research, Technological Development and Demonstration, Theme 2 - Biotechnologies

  7. Landslides risk mitigation along lifelines (United States)

    Capparelli, G.; Versace, P.; Artese, G.; Costanzo, S.; Corsonello, P.; Di Massa, G.; Mendicino, G.; Maletta, D.; Leone, S.; Muto, F.; Senatore, A.; Troncone, A.; Conte, E.; Galletta, D.


    The paper describes an integrated, innovative and efficient solution to manage risk issues associated to landslides interfering with infrastructures. The research project was submitted for financial support in the framework of the Multi -regional Operational Programme 2007-13: Research and Competitiveness funded by the Ministry of Research (MIUR) and co-funded by the European Regional Development Fund. The project is aimed to developing and demonstrating an integrated system of monitoring, early warning and mitigation of landslides risk. The final goal is to timely identify potentially dangerous landslides, and to activate all needed impact mitigation measures, including the information delivery. The essential components of the system include monitoring arrays, telecommunication networks and scenario simulation models, assisted by a data acquisition and processing centre, and a traffic control centres. Upon integration, the system will be experimentally validated and demonstrated over ca. 200 km of three highway sections, crossing the regions of Campania, Basilicata, Calabria and Sicily. Progress in the state of art is represented by the developments in the field of environmental monitoring and in the mathematical modeling of landslides and by the development of services for traffic management. The approach to the problem corresponds to a "systemic logics" where each developed component foresees different interchangeable technological solutions to maximize the operational flexibility. The final system may be configured as a simple to complex structure, including different configurations to deal with different scenarios. Specifically, six different monitoring systems will be realized: three "point" systems, made up of a network of locally measuring sensors, and three "area" systems to remotely measure the displacements of large areas. Each network will be fully integrated and connected to a unique data transmission system. Standardized and shared procedures for the

  8. Flicker Mitigation by Speed Control of Permanent Magnet Synchronous Generator Variable-Speed Wind Turbines

    Directory of Open Access Journals (Sweden)

    Yanting Hu


    Full Text Available Grid-connected wind turbines are fluctuating power sources that may produce flicker during continuous operation. This paper presents a simulation model of a MW-level variable speed wind turbine with a full-scale back-to-back power converter and permanent magnet synchronous generator (PMSG developed in the simulation tool of PSCAD/EMTDC. Flicker emission of this system is investigated. The 3p (three times per revolution power oscillation due to wind shear and tower shadow effects is the significant part in the flicker emission of variable speed wind turbines with PMSG during continuous operation. A new method of flicker mitigation by controlling the rotational speed is proposed. It smoothes the 3p active power oscillations from wind shear and tower shadow effects of the wind turbine by varying the rotational speed of the PMSG. Simulation results show that damping the 3p active power oscillation by using the flicker mitigation speed controller is an effective means for flicker mitigation of variable speed wind turbines with full-scale back-to-back power converters and PMSG during continuous operation.

  9. Mechanisms of Selenium Mitigating Stress and Accumulation of Heavy Metals in Plants

    Directory of Open Access Journals (Sweden)

    YUAN Si-li


    Full Text Available Selenium (Se plays an important role in improving plant stress resistance, mitigating heavy metal stress and reducing heavy metal uptake. This paper reviewed mechanisms involved with Se for mitigation of heavy metal stress and accumulation. Se could alleviate heavy metals stress because of the combined physiological and biochemical effects of the relevant products, including GSH-Px which could change toxic peroxides to non-toxic substances and remove free radicals induced by heavy metals. Se could activate phytochelatins synthase and increase the amount of precursors to phytochelatin (PC, and make plant produce more PC, and form more heavy metal-PC complexes. The formation of Se-heavy metal complexes reduced the biotoxicity of heavy metals. Se could produce antagonistic effect with a variety of heavy metals, and reduce the uptake of heavy metals.

  10. Mitigating uranium in groundwater: prospects and limitations. (United States)

    Noubactep, C; Meinrath, G; Dietrich, P; Merkel, B


    Removal of uranium(VI) by zerovalent iron has been suggested as a feasible pathway to control uranium contaminations in seepage waters. Available information in the literature however presents discrepant evidence on the process responsible for the mitigation effect. On basis of an EH-pH diagram of uranium and iron, it is outlined that these discrepancies may be explained by the aqueous chemistry of uranium and iron. Additional effects contributing to the complexity of the system are given. Solubilization experiments using scrap iron together with water works sludge, MnO2, and pyrite indicate that U(VI) is immobilized by iron corrosion products after about 50 days.

  11. Fur-bearers in the field : study examines cumulative effects of activity at Chinchaga

    Energy Technology Data Exchange (ETDEWEB)

    Jaremko, D.


    The challenges facing the oil and gas industry regarding cumulative environmental impacts were discussed. This issue has become important to the oil and gas industry, particularly as communities, governments, environmental groups and investors seek better understanding of the long-term consequences of development and how its effects can be mitigated. Long-term studies and baseline data are important. For the last 8 winters, Ernst Environmental Services (EES) has conducted wildlife monitoring at Chinchaga, which straddles the border between north-Western Alberta and northeastern British Columbia (BC). The area has been described as one of the last boreal wilderness areas in the province. It also has a very rich oil field. There are now more than 140 wells, and this boom has brought along much associated infrastructure, including pipelines, winter roads and a gas plant on the BC side. Each winter, as activity increases, EES uses snow-tracking, photo documentation, remote-camera monitoring and scat collection to capture data about the effects of drilling activities. Scat is collected for stress-level analysis. Although initial studies indicate that wolverines have not been displaced by oil and gas activity, new data has shown that wolverines have returned to territories where oil and gas activity has stopped. Data continues to support the idea that activity does not displace moose, marten, lynx or fisher populations. Using this data, the EES has made several recommendations about wildlife and industry interactions, including no use of recreational vehicles; no harassment of wildlife; the restriction of engine retarder brakes in specified areas; and no idling of vehicles. Additionally, well sites should not be located in old-growth areas, all activities should stop by March 15, and workers should be educated about the consequences of their actions. Controversies concerning the EES's methods were presented. It was suggested that the inefficacy of the procedure was

  12. Effect of physical activity on body composition

    Energy Technology Data Exchange (ETDEWEB)

    Zanzi, I; Ellis, K J; Aloia, J; Cohn, S H


    It has been noted that the deleterious effects on bone calcium of prolonged periods of inactivity, such as bed rest, are halted following resumption of activity. It would seem possible in light of the observations that have been made, that exercise may stimulate bone formation and perhaps counter, to some extent, bone loss as observed in the osteoporosis of aging. The present study was designed to determine the relation between total body calcium, total body potassium and bone mineral content of the radius to the degree of physical activity in a population of normal subjects. Measurement of the calcium was made by in-vivo total body neutron activation analysis. Bone mineral content of the radius and total body potassium, (an index of lean body mass) were measured by photon absorptiometry and the whole body counter, respectively.

  13. Radio Frequency Interference Mitigation at the WSRT

    CERN Document Server

    Fridman, P A; Millenaar, R P


    The sensitivity of radio astronomical stations is often limited by man-made radio frequency interference (RFI) due to a variety of terrestrial activities. An RFI mitigation subsystem (RFIMS) based on real-time digital signalprocessing is proposed here for the Westerbork Synthesis Radio Telescope based on a powerful field programmable gate array processor. In this system the radio astronomy signals polluted by RFI are "cleaned" with the RFIMS before routine back-end correlation processing takes place. The high temporal and frequency resolution of RFIMS allows the detection and excision of RFI better than do standard radio telescope back-end configurations.

  14. Antimicrobial Activity. (United States)


    Natural products of higher plants may possess a new source of antimicrobial agents with possibly novel mechanisms of action. They are effective in the treatment of infectious diseases while simultaneously mitigating many of the side effects that are often associated with conventional antimicrobials. A method using scanning electron microscope (SEM) to study the morphology of the bacterial and fungal microbes and thus determining antimicrobial activity is presented in the chapter.

  15. Effective diffusion of confined active Brownian swimmers (United States)

    Sandoval, Mario; Dagdug, Leonardo


    We find theoretically the effect of confinement and thermal fluctuations, on the diffusivity of a spherical active swimmer moving inside a two-dimensional narrow cavity of general shape. The explicit formulas for the effective diffusion coefficient of a swimmer moving inside two particular cavities are presented. We also compare our analytical results with Brownian Dynamics simulations and we obtain excellent agreement. L.D. thanks Consejo Nacional de Ciencia y Tecnologia (CONACyT) Mexico, for partial support by Grant No. 176452. M. S. thanks CONACyT and Programa de Mejoramiento de Profesorado (PROMEP) for partially funding this work under Grant No. 103.5/13/6732.

  16. Regulatory Effects of Fisetin on Microglial Activation


    Jing-Yuan Chuang; Pei-Chun Chang; Yi-Chun Shen; Chingju Lin; Cheng-Fang Tsai; Jia-Hong Chen; Wei-Lan Yeh; Ling-Hsuan Wu; Hsiao-Yun Lin; Yu-Shu Liu; Dah-Yuu Lu


    Increasing evidence suggests that inflammatory processes in the central nervous system that are mediated by microglial activation play a key role in neurodegeneration. Fisetin, a plant flavonol commonly found in fruits and vegetables, is frequently added to nutritional supplements due to its antioxidant properties. In the present study, treatment with fisetin inhibited microglial cell migration and ROS (reactive oxygen species) production. Treatment with fisetin also effectively inhibited LPS...

  17. Strategies to mitigate nitrous oxide emissions from herbivore production systems

    DEFF Research Database (Denmark)

    Schils, R L M; Eriksen, Jørgen; Ledgard, S F


    are necessary to avoid an increase in N2O emissions while meeting the growing global food demand. The production and emissions of N2O are closely linked to the efficiency of nitrogen (N) transfer between the major components of a livestock system, that is, animal, manure, soil and crop. Therefore, mitigation...... options in this paper have been structured along these N pathways. Mitigation technologies involving diet-based intervention include lowering the CP content or increasing the condensed tannin content of the diet. Animal-related mitigation options also include breeding for improved N conversion and high...... animal productivity. The main soil-based mitigation measures include efficient use of fertilizer and manure, including the use of nitrification inhibitors. In pasture-based systems with animal housing facilities, reducing grazing time is an effective option to reduce N2O losses. Crop-based options...

  18. Collaborative Monitoring and Hazard Mitigation at Fuego Volcano, Guatemala (United States)

    Lyons, J. J.; Bluth, G. J.; Rose, W. I.; Patrick, M.; Johnson, J. B.; Stix, J.


    A portable, digital sensor network has been installed to closely monitor changing activity at Fuego volcano, which takes advantage of an international collaborative effort among Guatemala, U.S. and Canadian universities, and the Peace Corps. The goal of this effort is to improve the understanding shallow internal processes, and consequently to more effectively mitigate volcanic hazards. Fuego volcano has had more than 60 historical eruptions and nearly-continuous activity make it an ideal laboratory to study volcanic processes. Close monitoring is needed to identify base-line activity, and rapidly identify and disseminate changes in the activity which might threaten nearby communities. The sensor network is comprised of a miniature DOAS ultraviolet spectrometer fitted with a system for automated plume scans, a digital video camera, and two seismo-acoustic stations and portable dataloggers. These sensors are on loan from scientists who visited Fuego during short field seasons and donated use of their sensors to a resident Peace Corps Masters International student from Michigan Technological University for extended data collection. The sensor network is based around the local volcano observatory maintained by Instituto National de Sismologia, Vulcanologia, Metrologia e Hidrologia (INSIVUMEH). INSIVUMEH provides local support and historical knowledge of Fuego activity as well as a secure location for storage of scientific equipment, data processing, and charging of the batteries that power the sensors. The complete sensor network came online in mid-February 2007 and here we present preliminary results from concurrent gas, seismic, and acoustic monitoring of activity from Fuego volcano.

  19. Greenhouse gas mitigation in agriculture. (United States)

    Smith, Pete; Martino, Daniel; Cai, Zucong; Gwary, Daniel; Janzen, Henry; Kumar, Pushpam; McCarl, Bruce; Ogle, Stephen; O'Mara, Frank; Rice, Charles; Scholes, Bob; Sirotenko, Oleg; Howden, Mark; McAllister, Tim; Pan, Genxing; Romanenkov, Vladimir; Schneider, Uwe; Towprayoon, Sirintornthep; Wattenbach, Martin; Smith, Jo


    Agricultural lands occupy 37% of the earth's land surface. Agriculture accounts for 52 and 84% of global anthropogenic methane and nitrous oxide emissions. Agricultural soils may also act as a sink or source for CO2, but the net flux is small. Many agricultural practices can potentially mitigate greenhouse gas (GHG) emissions, the most prominent of which are improved cropland and grazing land management and restoration of degraded lands and cultivated organic soils. Lower, but still significant mitigation potential is provided by water and rice management, set-aside, land use change and agroforestry, livestock management and manure management. The global technical mitigation potential from agriculture (excluding fossil fuel offsets from biomass) by 2030, considering all gases, is estimated to be approximately 5500-6000Mt CO2-eq.yr-1, with economic potentials of approximately 1500-1600, 2500-2700 and 4000-4300Mt CO2-eq.yr-1 at carbon prices of up to 20, up to 50 and up to 100 US$ t CO2-eq.-1, respectively. In addition, GHG emissions could be reduced by substitution of fossil fuels for energy production by agricultural feedstocks (e.g. crop residues, dung and dedicated energy crops). The economic mitigation potential of biomass energy from agriculture is estimated to be 640, 2240 and 16 000Mt CO2-eq.yr-1 at 0-20, 0-50 and 0-100 US$ t CO2-eq.-1, respectively.

  20. Fish and Wildlife Mitigation Plan (United States)



  1. Remote Sensing Technologies Mitigate Drought (United States)


    Ames Research Center has partnered with the California Department of Water Resources to develop satellite-based technologies to mitigate drought conditions. One project aims to help water managers adjust their irrigation to match the biological needs of each crop, and another involves monitoring areas where land is fallow so emergency relief can more quickly aid affected communities.

  2. The “New” Environmental Policy of the European Union: A Path to Development of a Circular Economy and Mitigation of the Negative Effects of Climate Change

    Directory of Open Access Journals (Sweden)

    Wysokińska Zofia


    Full Text Available This paper analyses the evolution of the new environmental policy of the European Union in the context of the efforts undertaken to moderate the negative effects of climate change. It describes all the activities in the European Union designed to implement new tools of the EU environmental policy, such as low carbon economy technologies, tools that improve the efficiency of managing the limited natural resources, the environmentally friendly transport package, etc. All of them are aimed at laying the foundations of the circular economy, which may also be referred to as a closed-loop economy, i.e., an economy that does not generate excessive waste and whereby any waste becomes a resource.

  3. Environmental Responses to Carbon Mitigation through Geological Storage

    Energy Technology Data Exchange (ETDEWEB)

    Cunningham, Alfred; Bromenshenk, Jerry


    In summary, this DOE EPSCoR project is contributing to the study of carbon mitigation through geological storage. Both deep and shallow subsurface research needs are being addressed through research directed at improved understanding of environmental responses associated with large scale injection of CO{sub 2} into geologic formations. The research plan has two interrelated research objectives. Objective 1: Determine the influence of CO{sub 2}-related injection of fluids on pore structure, material properties, and microbial activity in rock cores from potential geological carbon sequestration sites. Objective 2: Determine the Effects of CO{sub 2} leakage on shallow subsurface ecosystems (microbial and plant) using field experiments from an outdoor field testing facility.

  4. Harvesting SSL Certificate Data to Mitigate Web-Fraud

    CERN Document Server

    Mishari, Mishari Al; Defrawy, Karim El; Tsudik, Gene


    Web-fraud is one of the most unpleasant features of today's Internet. Two eminent examples of web-fraudulent activities are phishing and typosquatting. Phishing aims to elicit sensitive information from users by presenting them with mock-ups of legitimate web sites. Typosquatting is the nefarious practice of fielding web sites with names closely resembling those of legitimate and popular Internet destinations. Effects range from relatively benign (such as unwanted or unexpected ads) to downright sinister (especially, when typosquatting is combined with phishing). Prior work has assessed the risks of phishing and typosquatting and even attempted to profile and mitigate them. However, the problem remains largely unsolved. This paper presents a novel technique to detect web-fraud domains that utilize HTTPS. To achieve this, we conduct the first comprehensive study of SSL certificates for legitimate and popular domains, as opposed to those used for web-fraud. Drawing from extensive measurements, we build a classi...

  5. Ribavirin shows immunomodulatory effects on activated microglia. (United States)

    Savic, Danijela; Stojiljkovic, Mirjana; Lavrnja, Irena; Parabucki, Ana; Bjelobaba, Ivana; Nedeljkovic, Nadezda; Herdegen, Thomas; Pekovic, Sanja


    Abstract Ribavirin (RBV) is synthetic purine nucleoside analogue, licensed as anti-viral drug that displays immunomodulatory actions on various immune cells. Our previous ex vivo studies have demonstrated immunosuppressive effects of RBV on reactive T-lymphocytes in experimental autoimmune encephalomyelitis. Here, we examined the effects of RBV on inflammatory response of microglia. RBV potency to down-regulate microglia inflammatory response was assessed by measuring microglia cell body size, and the production of nitric oxide (NO) and pro- and anti-inflammatory cytokines. RBV exerted cytotoxic effects on LPS-stimulated microglia, leaving non-stimulated microglia unaffected. The exposure of activated microglia to RBV led to: decrease in the level of NO as a result of decreased cell number, lower average cell surface, the reduction of membrane ruffling, the suppression of interleukin-6 release and promoted interleukin-10 production. On the other hand, RBV promoted LPS-induced interleukin-1 beta release. Our results imply that RBV is a complex immunomodulator showing both anti- and pro-inflammatory effects on activated microglia.

  6. Integrating uncertainties for climate change mitigation (United States)

    Rogelj, Joeri; McCollum, David; Reisinger, Andy; Meinshausen, Malte; Riahi, Keywan


    The target of keeping global average temperature increase to below 2°C has emerged in the international climate debate more than a decade ago. In response, the scientific community has tried to estimate the costs of reaching such a target through modelling and scenario analysis. Producing such estimates remains a challenge, particularly because of relatively well-known, but ill-quantified uncertainties, and owing to limited integration of scientific knowledge across disciplines. The integrated assessment community, on one side, has extensively assessed the influence of technological and socio-economic uncertainties on low-carbon scenarios and associated costs. The climate modelling community, on the other side, has worked on achieving an increasingly better understanding of the geophysical response of the Earth system to emissions of greenhouse gases (GHG). This geophysical response remains a key uncertainty for the cost of mitigation scenarios but has only been integrated with assessments of other uncertainties in a rudimentary manner, i.e., for equilibrium conditions. To bridge this gap between the two research communities, we generate distributions of the costs associated with limiting transient global temperature increase to below specific temperature limits, taking into account uncertainties in multiple dimensions: geophysical, technological, social and political. In other words, uncertainties resulting from our incomplete knowledge about how the climate system precisely reacts to GHG emissions (geophysical uncertainties), about how society will develop (social uncertainties and choices), which technologies will be available (technological uncertainty and choices), when we choose to start acting globally on climate change (political choices), and how much money we are or are not willing to spend to achieve climate change mitigation. We find that political choices that delay mitigation have the largest effect on the cost-risk distribution, followed by

  7. Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy. (United States)

    Paran, Christopher W; Zou, Kai; Ferrara, Patrick J; Song, Haowei; Turk, John; Funai, Katsuhiko


    Muscular dystrophy is accompanied by a reduction in activity of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) that contributes to abnormal Ca(2+) homeostasis in sarco/endoplasmic reticulum (SR/ER). Recent findings suggest that skeletal muscle fatty acid synthase (FAS) modulates SERCA activity and muscle function via its effects on SR membrane phospholipids. In this study, we examined muscle's lipid metabolism in mdx mice, a mouse model for Duchenne muscular dystrophy (DMD). De novo lipogenesis was ~50% reduced in mdx muscles compared to wildtype (WT) muscles. Gene expressions of lipogenic and other ER lipid-modifying enzymes were found to be differentially expressed between wildtype (WT) and mdx muscles. A comprehensive examination of muscles' SR phospholipidome revealed elevated phosphatidylcholine (PC) and PC/phosphatidylethanolamine (PE) ratio in mdx compared to WT mice. Studies in primary myocytes suggested that defects in key lipogenic enzymes including FAS, stearoyl-CoA desaturase-1 (SCD1), and Lipin1 are likely contributing to reduced SERCA activity in mdx mice. Triple transgenic expression of FAS, SCD1, and Lipin1 (3TG) in mdx myocytes partly rescued SERCA activity, which coincided with an increase in SR PE that normalized PC/PE ratio. These findings implicate a defect in lipogenesis to be a contributing factor for SERCA dysfunction in muscular dystrophy. Restoration of muscle's lipogenic pathway appears to mitigate SERCA function through its effects on SR membrane composition.

  8. Leakage and comparative advantage implications of agricultural participation in greenhouse gas emission mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, H.C. [Western Ontario Univ., London, ON (Canada). Dept. of Economics; McCarl, B.A. [Texas A and M Univ., College Station, TX (United States). Dept. of Agricultural Economics; Schneider, U.A. [Hamburg Univ., Hamburg (Germany). Dept. of Geosciences and Economics; Chen, C.C. [National Chung Hsing Univ., Taichung, Taiwan (China). Dept. of Agricultural Economics


    Greenhouse gas (GHG) emissions reduction strategies may involve the agricultural sector through tree-planting initiatives, crop and livestock management changes and the production of biofuels. In a free trade arena, reduced domestic food production could stimulate increased production and exports in countries that are not pursuing mitigation options. As a result, net emission reductions in implementing countries may be offset by activities stimulated in other countries. The competitive effects of differential mitigation efforts on agricultural food production and international trade were investigated in this paper. A greenhouse gas (GHG) version of the United States (US) Agricultural Sector Model (ASM) was optimized with the addition of details on soil type dependent production and a global trade representation via spatial equilibrium models for 8 commodities. The combined model considered agricultural production, consumption, and trade in developed and developing countries simultaneously. Implementation was considered in 3 scenarios: (1) unilaterally by the US; (2) by all Kyoto Protocol Annex 1 countries; and (3) globally. Results indicated that compliance causes supply cut-backs in regulated countries and increases in non-regulated countries. Results also showed that US agricultural producers were likely to benefit from a Kyoto Protocol-like environment, but that consumers were likely to be negatively impacted in terms of their agricultural welfare. It was suggested that if national agricultural GHG mitigation policies are not synchronized with foreign GHG emission policies, substantial leakage may occur. Emission reductions in Annex 1 countries would most likely be accompanied by emission increases in developing countries. In addition, the abatement of GHG through the agricultural sector would result in higher agricultural commodity prices. It was observed that if implementation of an equivalent mitigation policy or clean development mechanism in all countries

  9. Effective equations governing an active poroelastic medium. (United States)

    Collis, J; Brown, D L; Hubbard, M E; O'Dea, R D


    In this work, we consider the spatial homogenization of a coupled transport and fluid-structure interaction model, to the end of deriving a system of effective equations describing the flow, elastic deformation and transport in an active poroelastic medium. The 'active' nature of the material results from a morphoelastic response to a chemical stimulant, in which the growth time scale is strongly separated from other elastic time scales. The resulting effective model is broadly relevant to the study of biological tissue growth, geophysical flows (e.g. swelling in coals and clays) and a wide range of industrial applications (e.g. absorbant hygiene products). The key contribution of this work is the derivation of a system of homogenized partial differential equations describing macroscale growth, coupled to transport of solute, that explicitly incorporates details of the structure and dynamics of the microscopic system, and, moreover, admits finite growth and deformation at the pore scale. The resulting macroscale model comprises a Biot-type system, augmented with additional terms pertaining to growth, coupled to an advection-reaction-diffusion equation. The resultant system of effective equations is then compared with other recent models under a selection of appropriate simplifying asymptotic limits.

  10. Industrial Energy Efficiency and Climate Change Mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Worrell, Ernst; Bernstein, Lenny; Roy, Joyashree; Price, Lynn; de la Rue du Can, Stephane; Harnisch, Jochen


    Industry contributes directly and indirectly (through consumed electricity) about 37% of the global greenhouse gas emissions, of which over 80% is from energy use. Total energy-related emissions, which were 9.9 GtCO2 in 2004, have grown by 65% since 1971. Even so, industry has almost continuously improved its energy efficiency over the past decades. In the near future, energy efficiency is potentially the most important and cost-effective means for mitigating greenhouse gas emissions from industry. This paper discusses the potential contribution of industrial energy efficiency technologies and policies to reduce energy use and greenhouse gas emissions to 2030.

  11. Mitigation of quantum dot cytotoxicity by microencapsulation.

    Directory of Open Access Journals (Sweden)

    Amelia Romoser

    Full Text Available When CdSe/ZnS-polyethyleneimine (PEI quantum dots (QDs are microencapsulated in polymeric microcapsules, human fibroblasts are protected from acute cytotoxic effects. Differences in cellular morphology, uptake, and viability were assessed after treatment with either microencapsulated or unencapsulated dots. Specifically, QDs contained in microcapsules terminated with polyethylene glycol (PEG mitigate contact with and uptake by cells, thus providing a tool to retain particle luminescence for applications such as extracellular sensing and imaging. The microcapsule serves as the "first line of defense" for containing the QDs. This enables the individual QD coating to be designed primarily to enhance the function of the biosensor.

  12. Mitigating Climate Change with Earth Orbital Sunshades (United States)

    Coverstone, Victoria; Johnson, Les


    An array of rotating sunshades based on emerging solar sail technology will be deployed in a novel Earth orbit to provide near-continuous partial shading of the Earth, reducing the heat input to the atmosphere by blocking a small percentage of the incoming sunlight, and mitigating local weather effects of anticipated climate change over the next century. The technology will provide local cooling relief during extreme heat events (and heating relief during extreme cold events) thereby saving human lives, agriculture, livestock, water and energy needs. A synthesis of the solar sail design, the sails' operational modes, and the selected orbit combine to provide local weather modification.

  13. Peaking of world oil production: Impacts, mitigation, & risk management

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, R.L. (SAIC); Bezdek, Roger (MISI); Wendling, Robert (MISI)


    The peaking of world oil production presents the U.S. and the world with an unprecedented risk management problem. As peaking is approached, liquid fuel prices and price volatility will increase dramatically, and, without timely mitigation, the economic, social, and political costs will be unprecedented. Viable mitigation options exist on both the supply and demand sides, but to have substantial impact, they must be initiated more than a decade in advance of peaking.... The purpose of this analysis was to identify the critical issues surrounding the occurrence and mitigation of world oil production peaking. We simplified many of the complexities in an effort to provide a transparent analysis. Nevertheless, our study is neither simple nor brief. We recognize that when oil prices escalate dramatically, there will be demand and economic impacts that will alter our simplified assumptions. Consideration of those feedbacks will be a daunting task but one that should be undertaken. Our aim in this study is to-- • Summarize the difficulties of oil production forecasting; • Identify the fundamentals that show why world oil production peaking is such a unique challenge; • Show why mitigation will take a decade or more of intense effort; • Examine the potential economic effects of oil peaking; • Describe what might be accomplished under three example mitigation scenarios. • Stimulate serious discussion of the problem, suggest more definitive studies, and engender interest in timely action to mitigate its impacts.

  14. Release mitigation spray safety systems for chemical demilitarization applications.

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, Jonathan; Tezak, Matthew Stephen; Brockmann, John E.; Servantes, Brandon; Sanchez, Andres L.; Tucker, Mark David; Allen, Ashley N.; Wilson, Mollye C.; Lucero, Daniel A.; Betty, Rita G.


    Sandia National Laboratories has conducted proof-of-concept experiments demonstrating effective knockdown and neutralization of aerosolized CBW simulants using charged DF-200 decontaminant sprays. DF-200 is an aqueous decontaminant, developed by Sandia National Laboratories, and procured and fielded by the US Military. Of significance is the potential application of this fundamental technology to numerous applications including mitigation and neutralization of releases arising during chemical demilitarization operations. A release mitigation spray safety system will remove airborne contaminants from an accidental release during operations, to protect personnel and limit contamination. Sandia National Laboratories recently (November, 2008) secured funding from the US Army's Program Manager for Non-Stockpile Chemical Materials Agency (PMNSCMA) to investigate use of mitigation spray systems for chemical demilitarization applications. For non-stockpile processes, mitigation spray systems co-located with the current Explosive Destruction System (EDS) will provide security both as an operational protective measure and in the event of an accidental release. Additionally, 'tented' mitigation spray systems for native or foreign remediation and recovery operations will contain accidental releases arising from removal of underground, unstable CBW munitions. A mitigation spray system for highly controlled stockpile operations will provide defense from accidental spills or leaks during routine procedures.

  15. Towards Incentivizing ISPs To Mitigate Botnets

    NARCIS (Netherlands)

    Lone, Q.B.; Moreira Moura, G.C.; Van Eeten, M.J.G.


    ISPs form a centralized point to control botnet infections. However, they do not have enough incentives to invest in mitigation of botnets. In this paper, we propose an approach based on comparative metrics to incentivize ISPs to mitigate botnets.

  16. IMS Mitigation Target Areas - 2010 [ds673 (United States)

    California Department of Resources — Mitigation Target Areas (MTA) were developed by the California Department of Fish and Game for the Interim Mitigation Strategy (IMS). The MTAs are an identification...

  17. FEMA Hazard Mitigation Grants Program Summary - API (United States)

    Department of Homeland Security — The Hazard Mitigation Grant Program (HMGP, CFDA Number: 97.039) provides grants to States and local governments to implement long-term hazard mitigation measures...

  18. FEMA Hazard Mitigation Grants Program Summary (United States)

    Department of Homeland Security — The Hazard Mitigation Grant Program (HMGP, CFDA Number: 97.039) provides grants to States and local governments to implement long-term hazard mitigation measures...

  19. Isoflavones: estrogenic activity, biological effect and bioavailability. (United States)

    Vitale, Daniela Cristina; Piazza, Cateno; Melilli, Barbara; Drago, Filippo; Salomone, Salvatore


    Isoflavones are phytoestrogens with potent estrogenic activity; genistein, daidzein and glycitein are the most active isoflavones found in soy beans. Phytoestrogens have similarity in structure with the human female hormone 17-β-estradiol, which can bind to both alpha and beta estrogen receptors, and mimic the action of estrogens on target organs, thereby exerting many health benefits when used in some hormone-dependent diseases. Numerous clinical studies claim benefits of genistein and daidzein in chemoprevention of breast and prostate cancer, cardiovascular disease and osteoporosis as well as in relieving postmenopausal symptoms. The ability of isoflavones to prevent cancer and other chronic diseases largely depends on pharmacokinetic properties of these compounds, in particular absorption and distribution to the target tissue. The chemical form in which isoflavones occur is important because it influences their bioavailability and, therefore, their biological activity. Glucose-conjugated isoflavones are highly polar, water-soluble compounds. They are hardly absorbed by the intestinal epithelium and have weaker biological activities than the corresponding aglycone. Different microbial families of colon can transform glycosylated isoflavones into aglycones. Clinical studies show important differences between the aglycone and conjugated forms of genistein and daidzein. The evaluation of isoflavone metabolism and bioavailability is crucial to understanding their biological effects. Lipid-based formulations such as drug incorporation into oils, emulsions and self-microemulsifying formulations have been introduced to increase bioavailability. Complexation with cyclodextrin also represent a valid method to improve the physicochemical characteristics of these substances in order to be absorbed and distributed to target tissues. We review and discuss pharmacokinetic issues that critically influence the biological activity of isoflavones.

  20. Effects of progesterone application on antioxidant enzyme activities and K+/Na+ ratio in bean seeds exposed to salt stress. (United States)

    Erdal, Serkan; Genisel, Mucip; Turk, Hulya; Gorcek, Zeynep


    This study aimed to investigate the influence of progesterone, a mammalian sex hormone, on germination of bean (Phaseolus vulgaris L.) seeds exposed to salt stress. The exogenous addition of 10(-6), 10(-8) and 10(-10) M progesterone to the stressing media in which bean seeds were germinated in combination with the salt (100 mM NaCl) stressor induced significant protective changes in the germination and early growth parameters. The mitigating effect of progesterone was evaluated by the measurement of radicle and plumule lengths, activities of antioxidant enzymes superoxide dismutase (SOD), peroxidase (POX) and catalase (CAT). In addition, it is the first study that exhibited changes in K/Na ratio. The obtained results showed that progesterone application stimulated germination and growth of salt-stressed seeds. Similarly, it stimulated significantly SOD, POX and CAT activities compared to both control and salt control. Salt stress significantly increased the lipid peroxidation compared to the control seeds. However, parallel to the increase in antioxidant activity, lipid peroxidation was significantly reduced by progesterone application. The best stimulatory effects on investigated parameters were recorded at 10(-8) M progesterone-applied seeds. On the other hand, salt stress reduced remarkably K/Na ratio by 50% in radicle and by 80% in plumule. However, progesterone application significantly mitigated the reduction in K/Na ratio. These findings clearly demonstrate that progesterone has a positive role in moderate detrimental effects induced by salt.

  1. The third hans cloos lecture. Urban landslides: Socioeconomic impacts and overview of mitigative strategies (United States)

    Schuster, R.L.; Highland, L.M.


    As a result of population pressures, hillsides in the world's urban areas are being developed at an accelerating rate. This development increases the risk for urban landslides triggered by rainfall or earthquake activity. To counter this risk, four approaches have been employed by landslide managers and urban planners: (1) restricting development in landslide-prone areas; (2) implementing and enforcing excavation, grading, and construction codes; (3) protecting existing developments by physical mitigation measures and (4) developing and installing monitoring and warning systems. Where they have been utilized, these approaches generally have been effective in reducing the risk due to landslide hazards. In addition to these practices, landslide insurance holds promise as a mitigative measure by reducing the financial impact of landslides on individual property owners. Until recently, however, such insurance has not been widely available and, where it is available, it is so expensive that it has been little used. ?? Springer-Verlag 2006.

  2. To protect or abandon: a participatory process on landslide risk mitigation (United States)

    Scolobig, A.; Bayer, J.; Cascini, L.; Ferlisi, S.


    With escalating costs of landslide risk mitigation and relief, a challenge for local authorities is to develop landslide risk mitigation measures that are viewed as efficient, feasible and fair by the many stakeholders involved. Innovative measures and the participation of stakeholders in the decision making process are essential elements in developing effective strategies to deal with the ever-changing spatial and temporal patterns of landslide risk. A stakeholder-led policy process, however, can face many social and economic challenges. One of the most difficult is deciding between costly protection measures or relocating homes. Particularly in areas with high population density, protection works are often not built because of economic/environmental constraints or private interests of the local residents. At the same time it not always possible to relocate households even if the costs are deemed less than protecting them. These issues turned out to be crucial in a recent participatory process for selecting risk mitigation measures in the town of Nocera Inferiore, Southern Italy, which experienced a landslide in 2005 causing three fatalities. The paper reports on this process which was structured in a series of meetings with a group of selected residents and several parallel activities open to the public. The preparatory work included semi-structured interviews carried out with key local stakeholders and a public survey eliciting residents' views on landslide risk mitigation. After describing the background of the landslide risk management problem in Nocera Inferiore, the paper focuses on three packages of risk mitigation measures (each of them not exceeding a total cost of 7 million Euro, namely the available funds) and the key trade-offs that emerged during the meetings with the residents. The participants reached a unanimous consensus on fundamental priorities, i.e. the improvement of the warning system, the implementation of an integrated system of monitoring

  3. Mitigative effects of spermidine on photosynthesis and carbon-nitrogen balance of cucumber seedlings under Ca(NO3)2 stress. (United States)

    Du, Jing; Shu, Sheng; Shao, Qiaosai; An, Yahong; Zhou, Heng; Guo, Shirong; Sun, Jin


    Ca(NO3)2 stress is one of the most serious constraints to plants production and limits the plants growth and development. Application of polyamines is a convenient and effective approach for enhancing plant salinity tolerance. The present investigation aimed to discover the photosynthetic carbon-nitrogen (C-N) mechanism underlying Ca(NO3)2 stress tolerance by spermidine (Spd) of cucumber (Cucumis sativus L. cv. Jinyou No. 4). Seedling growth and photosynthetic capacity [including net photosynthetic rate (P N), stomatal conductance (Gs), intercellular CO2 concentration (Ci), and transpiration rate (Tr)] were significantly inhibited by Ca(NO3)2 stress (80 mM). However, a leaf-applied Spd (1 mM) treatment alleviated the reduction in growth and photosynthesis in cucumber caused by Ca(NO3)2 stress. Furthermore, the application of exogenous Spd significantly decreased the accumulation of NO3 (-) and NH4 (+) caused by Ca(NO3)2 stress and remarkably increased the activities of N metabolism enzymes simultaneously. In addition, photosynthesis N-use efficiency (PNUE) and free amino acids were significantly enhanced by exogenous Spd in response to Ca(NO3)2 stress, thus promoting the biosynthesis of N containing compounds and soluble protein. Also, the amounts of several carbohydrates (including sucrose, fructose and glucose), total C content and the C/N radio increased significantly in the presence of Spd. Based on our results, we suggest that exogenous Spd could effectively accelerate nitrate transformation into amino acids and improve cucumber plant photosynthesis and C assimilation, thereby enhancing the ability of the plants to maintain their C/N balance, and eventually promote the growth of cucumber plants under Ca(NO3)2 stress.

  4. Regional transport sector mitigation options

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Peter [EECG Consultants, Gaborone (Botswana)


    The rationale for conducting climate change mitigation studies in the transport sector is on the premise that: The transport sector is the second largest consumer of fossil fuels in the region; The regional transport sector is an area with high opportunity for infrastructural development under UNFCCC financial mechanism; The regional transport sector is crucial in the SADC region for trade and coupled with the Trade Protocol will play a major role in development hence the need to make it efficient in terms of energy demand and provision of services; The sector offers many mitigation options but with a challenge to evaluate their energy saving and GHG saving potential and yet there is need to quantify possible emission reduction for possible future emission trading. This is also a sector with potential to qualify for financing through Clean Development Mechanism (CDM) recently stipulated in the Kyoto Protocol. (au)

  5. Effect of Combined Heavy Metal Pollution on Nitrogen Mineralization Potential,Urease and Phosphatase Activities in a Typic Udic Ferrisol

    Institute of Scientific and Technical Information of China (English)



    Individual and combined effects of Cu,Pb,Zn and Cd on N mineralization,urease and phosphatase were examined in a Typic Udic Ferrisol in laboratory by employing and uniform design and a single factor design,Soil pollution caused by heavy metals inhibited N mineralization (N0 value)and urease and phosphatase activities.The combined pollution of metals alleviated their toxicity to N mineralization to some extent whereas aggravated the toxicity to urease and phosphatase.Phosphorous application could mitigat the toxic effect of heavy metals on phosphatase activities,while alleviating effect of N application on the toxicity of heavy metals to urease was inconsistent.However,the mitigating effect of the fertilizers was limited in heavily polluted soils.

  6. Identifying and Mitigating Insider Threats

    DEFF Research Database (Denmark)

    Probst, Christian W.


    Organisations face many threats that coarsely can be separated in inside threats and outside threats. Threats from insiders are especially hard to counter since insiders have special knowledge and privileges. Therefore, malicious insider actions are hard to distinguish from benign actions. After...... discussing new definitions of insiders and insider threats, this article gives an overview of how to mitigate insider threats and discusses conflicting goals when dealing with insider threats....

  7. Hypoxia, Monitoring, and Mitigation System (United States)


    22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply...unlimited. 13. SUPPLEMENTARY NOTES The original document contains color images . 14. ABSTRACT The Hypoxia Monitoring, Alert and Mitigation System...was started in May. Optional Tasks 3, 4 and 5 have not been exercised . The second iteration of the arm mounted prototype is being fabricated and tested

  8. Environmental enrichment mitigates the sex-specific effects of gestational inflammation on social engagement and the hypothalamic pituitary adrenal axis-feedback system. (United States)

    Connors, E J; Shaik, A N; Migliore, M M; Kentner, A C


    Modest environmental enrichment (EE) is well recognized to protect and rescue the brain from the consequences of a variety of insults. Although animal models of maternal immune activation (MIA) are associated with several neurodevelopmental impairments in both the behavioral and cognitive functioning of offspring, the impact of EE in protecting or reversing these effects has not been fully evaluated. In the present study, female Sprague-Dawley rats were randomized into EE (pair-housed in a large multi-level cage with toys, tubes and ramps) or animal care control (ACC; pair-housed in standard cages) conditions. Each pair was bred, following assignment to their housing condition, and administered 100μg/kg of lipopolysaccharide (LPS) on gestational day 11. After birth, and until the end of the study, offspring were maintained in their respective housing conditions. EE protected against both the social and hypothalamic pituitary adrenal axis consequences of MIA in juvenile male rats, but surprisingly not against the spatial discrimination deficits or accompanying decrease in glutamate levels within the hippocampus (as measured via LCMS-MS). Based on these preliminary results, the mechanisms that underlie the sex-specific consequences that follow MIA appear to be dependent on environmental context. Together, this work highlights the importance of environmental complexity in the prevention of neurodevelopmental deficits following MIA.

  9. Optical and adhesive properties of dust deposits on solar mirrors and their effects on specular reflectivity and electrodynamic cleaning for mitigating energy-yield loss (United States)

    Mazumder, Malay; Yellowhair, Julius; Stark, Jeremy; Heiling, Calvin; Hudelson, John; Hao, Fang; Gibson, Hannah; Horenstein, Mark


    Large-scale solar plants are mostly installed in semi-arid and desert areas. In those areas, dust layer buildup on solar collectors becomes a major cause for energy yield loss. Development of transparent electrodynamic screens (EDS) and their applications for self-cleaning operation of solar mirrors are presented with a primary focus on the removal dust particles smaller than 30 µm in diameter while maintaining specular reflection efficiency surface. The electrodes are insulated from each other and are embedded within a thin transparent dielectric film. The electrodes are activated using three-phase high-voltage pulses at low current (electrostatic forces and propels the dust layer off of the collector's surface by a traveling wave. The cleaning process takes less than 2 minutes; needs energy less than 1 Wh/m2 without requiring any water or manual labor. The reflection efficiency can be restored > 95% of the original clean-mirror efficiency. We briefly present (1) loss of specular reflection efficiency as a function of particle size distribution of deposited dust, and (2) the effects of the electrode design and materials used for minimizing initial loss of specular reflectivity in producing EDS-integrated solar mirrors. Optimization of EDS by using a figure of merit defined by the ratio of dust removal efficiency to the initial loss of specular reflection efficiency is discussed.

  10. Mitigation potential and cost in tropical forestry - relative role for agroforestry

    Energy Technology Data Exchange (ETDEWEB)

    Makundi, Willy R.; Sathaye, Jayant A.


    This paper summarizes studies of carbon mitigation potential (MP) and costs of forestry options in seven developing countries with a focus on the role of agroforestry. A common methodological approach known as comprehensive mitigation assessment process (COMAP) was used in each study to estimate the potential and costs between 2000 and 2030. The approach requires the projection of baseline and mitigation land-use scenarios derived from the demand for forest products and forestland for other uses such as agriculture and pasture. By using data on estimated carbon sequestration, emission avoidance, costs and benefits, the model enables one to estimate cost effectiveness indicators based on monetary benefit per t C, as well as estimates of total mitigation costs and potential when the activities are implemented at equilibrium level. The results show that about half the MP of 6.9 Gt C (an average of 223 Mt C per year) between 2000 and 2030 in the seven countries could be achieved at a negative cost, and the other half at costs not exceeding $100 per t C. Negative cost indicates that non-carbon revenue is sufficient to offset direct costs of about half of the options. The agroforestry options analyzed bear a significant proportion of the potential at medium to low cost per t C when compared to other options. The role of agroforestry in these countries varied between 6% and 21% of the MP, though the options are much more cost effective than most due to the low wage or opportunity cost of rural labor. Agroforestry options are attractive due to the large number of people and potential area currently engaged in agriculture, but they pose unique challenges for carbon and cost accounting due to the dispersed nature of agricultural activities in the tropics, as well as specific difficulties arising from requirements for monitoring, verification, leakage assessment and the establishment of credible baselines.

  11. Climate change mitigation in Africa

    Energy Technology Data Exchange (ETDEWEB)

    Mackenzie, G.A.; Turkson, J.K.; Davidson, O.R. [eds.


    The UNEP Collaborating Centre on Energy and Environment (UCCEE) in conjunction with the Southern Centre for Energy and Environment (SCEE) hosted a conference on `Climate Change Mitigation in Africa` between 18 and 20 May. The Conference set out to address the following main objectives: to present to a wider audience the results of UNEP/GEF and related country studies; to present results of regional mitigation analysis; exchange of information with similar projects in the region; to expose countries to conceptual and methodological issues related to climate change mitigation; to provide input to national development using climate change related objectives. This volume contains reports of the presentations and discussions, which took place at the conference at Victoria Falls between 18 and 20 May 1998. Representatives of 11 country teams made presentations and in addition two sub-regions were discussed: the Maghreb region and SADC. The conference was attended by a total of 63 people, representing 22 African countries as well as international organisations. (EG)

  12. Regulatory Effects of Fisetin on Microglial Activation

    Directory of Open Access Journals (Sweden)

    Jing-Yuan Chuang


    Full Text Available Increasing evidence suggests that inflammatory processes in the central nervous system that are mediated by microglial activation play a key role in neurodegeneration. Fisetin, a plant flavonol commonly found in fruits and vegetables, is frequently added to nutritional supplements due to its antioxidant properties. In the present study, treatment with fisetin inhibited microglial cell migration and ROS (reactive oxygen species production. Treatment with fisetin also effectively inhibited LPS plus IFN-γ-induced nitric oxide (NO production, and inducible nitric oxide synthase (iNOS expression in microglial cells. Furthermore, fisetin also reduced expressions of iNOS and NO by stimulation of peptidoglycan, the major component of the Gram-positive bacterium cell wall. Fisetin also inhibited the enhancement of LPS/IFN-γ- or peptidoglycan-induced inflammatory mediator IL (interlukin-1 β expression. Besides the antioxidative and anti-inflammatory effects of fisetin, our study also elucidates the manner in fisetin-induced an endogenous anti-oxidative enzyme HO (heme oxygenase-1 expression. Moreover, the regulatory molecular mechanism of fisetin-induced HO-1 expression operates through the PI-3 kinase/AKT and p38 signaling pathways in microglia. Notably, fisetin also significantly attenuated inflammation-related microglial activation and coordination deficit in mice in vivo. These findings suggest that fisetin may be a candidate agent for the development of therapies for inflammation-related neurodegenerative diseases.

  13. Regulatory effects of fisetin on microglial activation. (United States)

    Chuang, Jing-Yuan; Chang, Pei-Chun; Shen, Yi-Chun; Lin, Chingju; Tsai, Cheng-Fang; Chen, Jia-Hong; Yeh, Wei-Lan; Wu, Ling-Hsuan; Lin, Hsiao-Yun; Liu, Yu-Shu; Lu, Dah-Yuu


    Increasing evidence suggests that inflammatory processes in the central nervous system that are mediated by microglial activation play a key role in neurodegeneration. Fisetin, a plant flavonol commonly found in fruits and vegetables, is frequently added to nutritional supplements due to its antioxidant properties. In the present study, treatment with fisetin inhibited microglial cell migration and ROS (reactive oxygen species) production. Treatment with fisetin also effectively inhibited LPS plus IFN-γ-induced nitric oxide (NO) production, and inducible nitric oxide synthase (iNOS) expression in microglial cells. Furthermore, fisetin also reduced expressions of iNOS and NO by stimulation of peptidoglycan, the major component of the Gram-positive bacterium cell wall. Fisetin also inhibited the enhancement of LPS/IFN-γ- or peptidoglycan-induced inflammatory mediator IL (interlukin)-1 β expression. Besides the antioxidative and anti-inflammatory effects of fisetin, our study also elucidates the manner in fisetin-induced an endogenous anti-oxidative enzyme HO (heme oxygenase)-1 expression. Moreover, the regulatory molecular mechanism of fisetin-induced HO-1 expression operates through the PI-3 kinase/AKT and p38 signaling pathways in microglia. Notably, fisetin also significantly attenuated inflammation-related microglial activation and coordination deficit in mice in vivo. These findings suggest that fisetin may be a candidate agent for the development of therapies for inflammation-related neurodegenerative diseases.

  14. Effect of powdered activated carbon on integrated submerged membrane bioreactor-nanofiltration process for wastewater reclamation. (United States)

    Woo, Yun Chul; Lee, Jeong Jun; Shim, Wang-Geun; Shon, Ho Kyong; Tijing, Leonard D; Yao, Minwei; Kim, Han-Seung


    The aim of this study was to determine the effect of powdered activated carbon (PAC) on the overall performance of a submerged membrane bioreactor (SMBR) system integrated with nanofiltration (NF) for wastewater reclamation. It was found that the trans-membrane pressure of SMBR increased continuously while that of the SMBR with PAC was more stable, mainly because water could still pass through the PACs and membrane even though foulants adhered on the PAC surface. The presence of PAC was able to mitigate fouling in SMBR as well as in NF. SMBR-NF with PAC obtained a higher flux of 8.1 LMH compared to that without PAC (6.6 LMH). In addition, better permeate quality was obtained with SMBR-NF integrated process added with PAC. The present results suggest that the addition of PAC in integrated SMBR-NF process could possibly lead to satisfying water quality and can be opera