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Sample records for activation analysis body

  1. Analysis of Relationship between the Body Mass Composition and Physical Activity with Body Posture in Children

    Directory of Open Access Journals (Sweden)

    Justyna Wyszyńska

    2016-01-01

    Full Text Available Introduction. Excessive body mass in turn may contribute to the development of many health disorders including disorders of musculoskeletal system, which still develops intensively at that time. Aim. The aim of this study was to assess the relationship between children’s body mass composition and body posture. The relationship between physical activity level of children and the parameters characterizing their posture was also evaluated. Material and Methods. 120 school age children between 11 and 13 years were enrolled in the study, including 61 girls and 59 boys. Each study participant had the posture evaluated with the photogrammetric method using the projection moiré phenomenon. Moreover, body mass composition and the level of physical activity were evaluated. Results. Children with the lowest content of muscle tissue showed the highest difference in the height of the inferior angles of the scapulas in the coronal plane. Children with excessive body fat had less slope of the thoracic-lumbar spine, greater difference in the depth of the inferior angles of the scapula, and greater angle of the shoulder line. The individuals with higher level of physical activity have a smaller angle of body inclination. Conclusion. The content of muscle tissue, adipose tissue, and physical activity level determines the variability of the parameter characterizing the body posture.

  2. Body composition as measured by in vivo neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S.H.; Sawitsky, A.; Vartsky, D.; Yasumura, S.; Zanzi, I.; Gartenhaus, W.; Ellis, K.J.

    1979-01-01

    A large scale study is currently underway on the changes in body composition resulting from the cachexia of malignancy. The ultimate objective of the overall project is to assess the changes in body composition associated with hyperalimentation and other modes of nutritional support to cancer patients. The first phase of this study is now in progress. In this phase, a study is being made of a control group of normal patients to provide baseline data against which data from cancer patients can be evaluated. Total body nitrogen and potassium are measured in a group of normal men and women, and are analyzed as a function of age. Additionally, changes in skeletal mass (total body calcium) are also recorded, and body water is measured simultaneously with the use of tritiated water.

  3. Analysis of Body Shapes and Physical Activity Dominant Patterns in a Coloring Books Collection

    Directory of Open Access Journals (Sweden)

    Vladimir Martínez Bello

    2014-06-01

    Full Text Available Curriculum materials play an important role in the construction of the concept of the body to the extent that they are transmitters of knowledge, ideas and values. The aim of the study was to analyse whether the images in a collection of coloring books entitled The Boys´ Doodles Book and The girl´s Doodles Book show sexist stereotypes about body models and dominant patterns of physical activity. An independent observational group studied the images of the body through content analysis with a coding scheme using categories (gender, age, somatotype, space and type of physical activity previously adopted by experts. The Boys´ Doodles Book shows an adult man with different body types, while women are not represented. In both books, the bodies do not maintain a preferred location. The Girls´Doodles Book represents a higher percentage of girls with a slender body, while men, who were under-represented, assume different body types. The Girls´Doodles Book tends to represent women in physical activities or sports with an artistic component. In conclusion, the images in both coloring books, promote sexist body shapes and physical activities. It is a warning to parents and mothers, as well as publishing houses, libraries and government agencies to critically analyse underlying patterns on coloring books.

  4. Apparatus for the measurement of total body nitrogen using prompt neutron activation analysis with californium-252.

    Science.gov (United States)

    Mackie, A; Hannan, W J; Smith, M A; Tothill, P

    1988-01-01

    Details of clinical apparatus designed for the measurement of total body nitrogen (as an indicator of body protein), suitable for the critically ill, intensive-care patient are presented. Californium-252 radio-isotopic neutron sources are used, enabling a nitrogen measurement by prompt neutron activation analysis to be made in 40 min with a precision of +/- 3.2% for a whole body dose equivalent of 0.145 mSv. The advantages of Californium-252 over alternative neutron sources are discussed. A comparison between two irradiation/detection geometries is made, leading to an explanation of the geometry adopted for the apparatus. The choice of construction and shielding materials to reduce the count rate at the detectors and consequently to reduce the pile-up contribution to the nitrogen background is discussed. Salient features of the gamma ray spectroscopy system to reduce spectral distortion from pulse pile-up are presented.

  5. Effect of physical activity on body composition

    Energy Technology Data Exchange (ETDEWEB)

    Zanzi, I; Ellis, K J; Aloia, J; Cohn, S H

    1980-01-01

    It has been noted that the deleterious effects on bone calcium of prolonged periods of inactivity, such as bed rest, are halted following resumption of activity. It would seem possible in light of the observations that have been made, that exercise may stimulate bone formation and perhaps counter, to some extent, bone loss as observed in the osteoporosis of aging. The present study was designed to determine the relation between total body calcium, total body potassium and bone mineral content of the radius to the degree of physical activity in a population of normal subjects. Measurement of the calcium was made by in-vivo total body neutron activation analysis. Bone mineral content of the radius and total body potassium, (an index of lean body mass) were measured by photon absorptiometry and the whole body counter, respectively.

  6. The effect of school-based physical activity interventions on body mass index: a meta-analysis of randomized trials

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Guerra

    2013-09-01

    Full Text Available This study reviewed the effectiveness of school-based physical activity interventions aimed at reducing overweight, obesity and hypertension in children. We searched 14 databases and analyzed studies published between April 2009 and September 2012. Only randomized controlled trials performed at the school level that included elements of physical activity but did not include nutritional co-interventions were analyzed. Studies were assessed by two recommended tools (EPHPP and GRADE, and the standardized mean differences with 95% confidence intervals were collected for a random-effect meta-analysis. A total of 12 papers were included in the meta-analysis, and these were divided according to three outcomes: body mass index (11 trials, n  =  4,273, −0.02, 95% CI: −0.13 to 0.17, p  =  0.8; body weight (5 trials, n  =  1,330, −0.07, 95% CI: −0.18 to 0.04, p  =  0.2; and blood pressure (6 trials, n  =  1,549, including systolic (0.11, 95% CI: −0.10 to 0.31, p  =  0.3 and diastolic pressure (−0.00, 95% CI: −0.10 to 0.10, p  =  0.9. This meta-analysis of data from 11 randomized, school-based physical activity interventions suggests that, regardless of the potential benefits of physical activity in the school environment, the interventions did not have a statistically significant effect. However, it is difficult to generalize from these results because the duration, intensity and type of physical activity used in the interventions varied greatly.

  7. Sport-based physical activity intervention on body weight in children and adolescents: a meta-analysis.

    Science.gov (United States)

    Kim, Kyungun; Ok, Gina; Jeon, Soeun; Kang, Minsoo; Lee, Sukho

    2017-02-01

    Controversial results reported in past research pertaining to the effectiveness of sport-based physical activity interventions on weight loss. The purpose of this study was to assess the impact of sport-based physical activity intervention on body weight in children and adolescents using a meta-analysis. Academic Search Complete, Education Source, ERIC, Medline, ProQuest, PsycINFO and SportDiscus databases were searched from January 2000 to April 2015. Eighteen studies met following inclusion criteria: sport-based intervention studies; subjects aged 6-18 years; reported body weight; published in peer-reviewed journals written in English. The mean intervention duration was 17.72 weeks. The overall effect size (ES) was 0.52 (Cohen's d (ES) = 0.52, 95% CI = 0.08, 0.95, P = 0.021), using a random effects model. Moderator analyses results showed that the Q statistic for the sport type (individual sport or team sport, Qbetween (Qb) = 14.52, df = 1, P = 0.001) and diet control (Qbetween (Qb) = 8.85, df = 1, P = 0.001), explained the heterogeneity of ESs. Our study showed that there was a moderate overall effect of sport-based physical activity intervention on body weight reduction. The team sport type (ES = 1.05, 95% CI = 0.44, 1.66) and diet control group (ES = 0.84, 95% CI = 0.26, 1.41) appeared to be more effective in reducing body weight.

  8. The functional architecture of the human body: assessing body representation by sorting body parts and activities.

    Science.gov (United States)

    Bläsing, Bettina; Schack, Thomas; Brugger, Peter

    2010-05-01

    We investigated mental representations of body parts and body-related activities in two subjects with congenitally absent limbs (one with, the other without phantom sensations), a wheelchair sports group of paraplegic participants, and two groups of participants with intact limbs. To analyse mental representation structures, we applied Structure Dimensional Analysis. Verbal labels indicating body parts and related activities were presented in randomized lists that had to be sorted according to a hierarchical splitting paradigm. Participants were required to group the items according to whether or not they were considered related, based on their own body perception. Results of the groups of physically intact and paraplegic participants revealed separate clusters for the lower body, upper body, fingers and head. The participant with congenital phantom limbs also showed a clear separation between upper and lower body (but not between fingers and hands). In the participant without phantom sensations of the absent arms, no such modularity emerged, but the specific practice of his right foot in communication and daily routines was reflected. Sorting verbal labels of body parts and activities appears a useful method to assess body representation in individuals with special body anatomy or function and leads to conclusions largely compatible with other assessment procedures.

  9. Physical activity, body composition and lipids changes in adolescents: analysis from the MyHeART Study.

    Science.gov (United States)

    Majid, Hazreen Abdul; Amiri, Mohammadreza; Mohd Azmi, Nahar; Su, Tin Tin; Jalaludin, Muhammad Yazid; Al-Sadat, Nabilla

    2016-01-01

    Insufficient physical activity and growing obesity levels among Malaysian adolescents are becoming a public health concern. Our study is to identify the trends of self-reported physical activity (PA) levels, blood lipid profiles, and body composition (BC) indices from a cohort of 820 adolescents. The self-reported PA was assessed using a validated Malay version of the PA Questionnaire for Older Children (PAQ-C). Fasting blood samples were collected to investigate their lipid profiles. Height, weight, waist and hip circumferences as well as body fat percentage were measured. The baseline and the first follow-up were conducted in 2012 and 2014, respectively. A downward trend in the PA level was seen in all categories with a significant reduction among all rural adolescents (P = 0.013) and more specifically, PA among girls residing in rural areas dropped significantly (P = 0.006). Either a significant reduction in high-density lipoprotein (HDL) or a significant increment in BC indices (i.e., body mass index [BMI], waist circumference [WC], hip circumference, and body fat percentage [BF %]) were seen in this group. Female adolescents experienced more body fat increment with the reduction of physical activity. If not intervened early, adolescents from rural areas may increase their risk of developing cardiovascular diseases earlier.

  10. A STUDY ESTABLISHING THE IMPORTANCE OF INDIVIDUALIZED EXERCISE PRESCRIPTION IN PHYSIOTHERAPY FOR ACHIEVING PHYSICAL FITNESS BY COMPARATIVE ANALYSIS OF BODY COMPOSITION, PHYSICAL CHARACTERISTICS AND PHYSICAL ACTIVITY

    OpenAIRE

    Dr. Rohit Subhedar; Dr. Pallavi Dave; Dr. Priyanka Mishra; Dr. Dirgha Mehta

    2015-01-01

    Background: This study deals with the evaluation of body composition and fitness of individuals who differ in their physical characteristics viz. weight, height, Age, Sex, Body Frame and physical activity levels viz. Heavy, Moderate, Light, and thereby identify the ideal combination of physical characteristics and physical activity required in Prescribing Exercises for attaining “THE PERFECT BODY COMPOSITION”. Method: Assessments of physical characteristics, physical activity and body comp...

  11. A Human Body Analysis System

    Directory of Open Access Journals (Sweden)

    Girondel Vincent

    2006-01-01

    Full Text Available This paper describes a system for human body analysis (segmentation, tracking, face/hands localisation, posture recognition from a single view that is fast and completely automatic. The system first extracts low-level data and uses part of the data for high-level interpretation. It can detect and track several persons even if they merge or are completely occluded by another person from the camera's point of view. For the high-level interpretation step, static posture recognition is performed using a belief theory-based classifier. The belief theory is considered here as a new approach for performing posture recognition and classification using imprecise and/or conflicting data. Four different static postures are considered: standing, sitting, squatting, and lying. The aim of this paper is to give a global view and an evaluation of the performances of the entire system and to describe in detail each of its processing steps, whereas our previous publications focused on a single part of the system. The efficiency and the limits of the system have been highlighted on a database of more than fifty video sequences where a dozen different individuals appear. This system allows real-time processing and aims at monitoring elderly people in video surveillance applications or at the mixing of real and virtual worlds in ambient intelligence systems.

  12. Total body carbon and oxygen masses: evaluation of dual-energy x-ray absorptiometry estimation by in vivo neutron activation analysis

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    Wang, ZiMian; Pierson, Richard N., Jr.

    2010-10-01

    Oxygen and carbon are the first and second abundant elements, respectively, in the human body by mass. Although many physiological and pathological processes are accompanied with alteration of total body oxygen (TBO) and carbon (TBC) masses, in vivo measurements of the two elements are limited. Up to now, almost all available information of TBC and TBO is based on in vivo neutron activation (IVNA) analysis which is very expensive and involves moderate radiation exposure. The aim of the present study was to develop and evaluate an alternative strategy for TBC and TBO estimation. Mechanistic models were derived for predicting TBC and TBO masses from dual-energy x-ray absorptiometry (DXA) and total body water (TBW). Twenty-eight adult subjects were studied. IVNA-measured TBC and TBO masses were used as the criterion. TBC masses predicted by DXA-alone and by DXA-TBW models were 20.8 ± 7.1 kg and 20.6 ± 6.8 kg, respectively, close to the IVNA-measured value (19.5 ± 6.3 kg). There were strong correlations (both with r > 0.95, P 0.97, P < 0.001) were strong between the predicted and measured TBO masses. Bland-Altman analysis validated the applicability of DXA-based models to predict TBC and TBO masses. As both DXA and TBW dilutions are widely available, low-risk, low-cost techniques, the present study provides a safe and practical method for estimating elemental composition in vivo.

  13. A Low Speed Model Analysis and Demonstration of Active Control Systems for Rigid-Body and Flexible Mode Stability

    Science.gov (United States)

    1974-06-01

    might be to sum the signals directly using complex algebra . This approach may better be handled in a digital system. Servovalve Magnetic Coupling The...France, 1969. *’ 18. L- Coven and C. F. Durbin , A Cmprehensive Eigensolution Program for Structural Vibration Analysis TEV 142. Boeing Document D6

  14. Active children and quiet bodies wanted!

    DEFF Research Database (Denmark)

    Jensen, Jens-Ole

    2015-01-01

    Active children and quiet bodies wanted! A new school law was implemented in the Danish primary and secondary school system from August 2014. The main purpose of the law is to: – challenge all pupils to become as skilled as possible, – lower the consequences of social background in order to achieve...... better results and – strengthen the confidence to and the wellbeing in the school. These objectives should among other initiatives be achieved by a longer and more diversified school day. Physical activities and movements have been seen as an important tool to create more varied forms of teaching...... education the physical activities and movements should be integrated in the academic subjects as active teaching and brain breaks etc. or as organized activities during the extended school day. By doing fieldwork and interviewing pupils from grade 0-2 the study investigate how these changes are experienced...

  15. Self-objectification, body self-consciousness during sexual activities, and sexual satisfaction in college women.

    Science.gov (United States)

    Claudat, Kim; Warren, Cortney S

    2014-09-01

    Few studies examine the mechanisms that link body image to sexual satisfaction in women. Using the tenets of objectification theory, this study investigated the relationships between body surveillance, body shame, body self-consciousness during sexual activities, and sexual satisfaction in an ethnically diverse sample of American female college students (N=368), while controlling for relationship status and body mass index. Results based on self-report measures of these constructs suggested that body shame and body self-consciousness during sexual activity were negatively correlated with sexual satisfaction. Additionally, path analysis indicated that body surveillance predicted increased body self-consciousness during sexual activity, partially mediated by body shame. Body self-consciousness, in turn, predicted decreased sexual satisfaction. Overall, study findings highlight the negative consequences of body image concerns for women's sexual satisfaction.

  16. Telomerase activity coevolves with body mass, not lifespan

    Science.gov (United States)

    Seluanov, Andrei; Chen, Zhuoxun; Hine, Christopher; Sasahara, Tais H. C.; Ribeiro, Antonio A. C. M.; Catania, Kenneth C.; Presgraves, Daven C.; Gorbunova, Vera

    2009-01-01

    Summary In multicellular organisms, telomerase is required to maintain telomere length in the germline but is dispensable in the soma. Mice, for example, express telomerase in somatic and germline tissues, while humans express telomerase almost exclusively in the germline. As a result, when telomeres of human somatic cells reach a critical length the cells enter irreversible growth arrest called replicative senescence. Replicative senescence is believed to be an anticancer mechanism that limits cell proliferation. The difference between mice and humans led to the hypothesis that repression of telomerase in somatic cells has evolved as a tumor-suppressor adaptation in large, long-lived organisms. We tested whether regulation of telomerase activity coevolves with lifespan and body mass using comparative analysis of 15 rodent species with highly diverse lifespans and body masses. Here we show that telomerase activity does not coevolve with lifespan but instead coevolves with body mass: larger rodents repress telomerase activity in somatic cells. These results suggest that large body mass presents a greater risk of cancer than long lifespan, and large animals evolve repression of telomerase activity to mitigate that risk. PMID:17173545

  17. Influence of age, menopause status, body mass index and physical activity on body composition and body fat distribution in midlife women

    Institute of Scientific and Technical Information of China (English)

    Wei Dai-min; Yu Qi; Zhang Ying; Chen Feng-ling

    2012-01-01

    Objective: To investigate the influence of age,menopause status,body mass index (BMI) and physical activity on body composition and body fat distribution in Chinese midlife women.Methods: The healthy women who underwent anniversary health checkup in Peking Union Medical College Hospital were recruited cross-sectionally.The level of physical activity was determined via International Physical Activity Questionnaire-Short in Chinese Version.The body composition and fat distribution were measured by dualenergy X-ray absorptiometry.Results: A total of 162 women with average age 52 years (40-62 years) were recruited.Multivariate linear regression analysis was performed to test the relationship between age,menopause status,BMI and physical activity and parameters of body composition and body fat distribution.The total fat tissue percentage was positively associated with BMI (standardized partial regression coefficient: b=0.70),menopause status (b=0.19,grading variables 1,2,3 were assigned to represent for reproductive group,menopausal transition group and postmenopausal group,respectively),and negatively associated with physical activity energy expenditure (b=-0.17) with model determination coefficient 0.55.Total body fat-free-tissue mass was positively associated with BMI (b =0.61),negatively associated with menopause status (b =-0.14) with model determination coefficient 0.39.The ratio of trunk fat-tissue mass/total body fat-tissue mass (Tr/T) was positively associated with BMI (b=0.32) and menopause status (b= 0.30) with model determination coefficient 0.20.After adjusted the effects of BMI,menopause status and physical activity,age was not significantly related with total fat tissue percentage,body fat-free-tissue mass,nor ratio of (Tr/T).Conclusion: Menopause impacts body composition and body fat distribution independently.During the process of female reproductive aging,body fat tissue mass and centrally distributed fat tissue mass increase,while body fatfree

  18. Characterization of abandoned rocket body families for active removal

    Science.gov (United States)

    Pardini, Carmen; Anselmo, Luciano

    2016-09-01

    A new ranking index was developed and applied to a wide set of rocket body families, characterized by stage dry masses greater than 500 kg and by the presence of at least 5 stages abandoned in LEO. The upper stages selected accounted for more than 80% of the unclassified rocket bodies in LEO and nearly 95% of the associated dry mass. The detailed results obtained for 657 objects clearly identified the most critical altitude-inclination bands and stage models, to be targeted first if and when a debris remediation strategy including the active removal of intact abandoned objects were deemed necessary. Apart from the evaluation of the criticality regarding the long-term evolution of the debris environment, resulting in a priority listing for optimal active removal, the application of the new ranking index is not limited to debris remediation. In fact, if applied before launch to spacecraft and rocket bodies to be disposed in orbit, at the end of mission, it would provide an additional debris mitigation analysis tool for evaluating competing disposal options. Concerning the rocket bodies abandoned in LEO, 274 resulted to have a criticality equal or larger than the average intact object abandoned in an 800 km sun-synchronous orbit. Among them, 243 belonged to the Russian Federation and Ukraine, 25 to China, 5 to Europe and 1 to Japan. In addition to being concentrated in relatively few and narrow altitude-inclinations bands, the most numerous rocket body families often present a quite uniform distribution in right ascension of the ascending node, which is especially convenient for multiple target removal missions.

  19. Immunological network activation by low-dose rate irradiation. Analysis of cell populations and cell surface molecules in whole body irradiated mice

    Energy Technology Data Exchange (ETDEWEB)

    Ina, Yasuhiro; Sakai, Kazuo [Central Research Inst. of Electric Power Industry, Low Dose Radiation Research Center, Komae, Tokyo (Japan)

    2003-07-01

    The effects of low-dose rate whole body irradiation on biodefense and immunological systems were investigated using female C57BL/6 (B6) mice. These B6 mice were exposed continuously to {gamma}-rays from a {sup 137}Cs source in the long-term low-dose rate irradiation facility at CRIEPI for 0 - 12 weeks at a dose rate of 0.95 mGy/hr. In the bone marrow, thymus, spleen, lymph nodes, and peripheral blood of the irradiated mice, changes in cell populations and cell surface molecules were examined. The cell surface functional molecules (CD3, CD4, CD8, CD19, CD45R/B220, ICAM-1, Fas, NK-1.1, CXCR4, and CCR5), and activation molecules (THAM, CD28, CD40, CD44H, CD70, B7-1, B7-2, OX-40 antigen, CTLA-4, CD30 ligand, and CD40 ligand) were analyzed by flow cytometry. The percentage of CD4{sup +} T cells and cell surface CD8 molecule expressions on the CD8{sup +} T cells increased significantly to 120-130% after 3 weeks of the irradiation, compared to non-irradiated control mice. On the other hand, the percentage of CD45R/B220{sup +} CD40{sup +} B cells, which is one of the immunological markers of inflammation, infection, tumor, and autoimmune disease, decreased significantly to 80-90% between the 3rd to 5th week of irradiation. There was no significant difference in other cell population rates and cell surface molecule expression. Furthermore, abnormal T cells bearing mutated T cell receptors induced by high-dose rate irradiation were not observed throughout this study. These results suggest that low-dose rate irradiation activates the immunological status of the whole body. (author)

  20. The Effect of Physical Exercise on Postural Stability in Sighted Individuals and Those Who Are Visually Impaired: An Analysis Adjusted for Physical Activity and Body Mass Index.

    Science.gov (United States)

    Sadowska, Dorota; Stemplewski, Rafał; Szeklicki, Robert

    2015-10-01

    The aim of this study was to assess the effect of physical exercise on postural stability in sighted participants and individuals who are visually impaired, adjusted for potential modulatory effects of physical activity level and body mass index (BMI). The study included 23 participants who were severely visually impaired and 23 sighted participants. Postural stability measurements were taken with open eyes (session I) and with closed eyes (session II). During each session, the mean velocity of the center of pressure (COP) displacements was determined using a force plate both before and after physical exercise. During testing with open eyes, the 2 groups did not differ significantly in terms of their postural response to physical exercise. When examined with closed eyes, the individuals who were visually impaired showed markedly greater postexercise increase in mean velocity of the COP displacement in the mediolateral direction. This intergroup difference was likely a consequence of significantly higher preexercise values of posturographic parameters observed in the sighted participants. More pronounced postexercise changes in the postural stability of sighted participants were associated with lower levels of physical activity and higher values of BMI. Further research is needed to explain the character of the abovementioned relationships in individuals who are visually impaired.

  1. Mushroom Bodies Suppress Locomotor Activity in Drosophila melanogaster

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    Martin, Jean-René; Ernst, Roman; Heisenberg, Martin

    1998-01-01

    Locomotor activity of single, freely walking flies in small tubes is analyzed in the time domain of several hours. To assess the influence of the mushroom bodies on walking activity, three independent noninvasive methods interfering with mushroom body function are applied: chemical ablation of the mushroom body precursor cells; a mutant affecting Kenyon cell differentiation (mushroom body miniature1); and the targeted expression of the catalytic subunit of tetanus toxin in subsets of Kenyon cells. All groups of flies with mushroom body defects show an elevated level of total walking activity. This increase is attributable to the slower and less complete attenuation of activity during the experiment. Walking activity in normal and mushroom body-deficient flies is clustered in active phases (bouts) and rest periods (pauses). Neither the initiation nor the internal structure, but solely the termination of bouts seems to be affected by the mushroom body defects. How this finding relates to the well-documented role of the mushroom bodies in olfactory learning and memory remains to be understood. PMID:10454382

  2. The Relationship between Physical Activity Level, Body Mass Index, and Body Fat Percentages in Urban and Rural Elementary School Students

    Science.gov (United States)

    Orhan, Özlem

    2015-01-01

    The purpose of this study is to compare the physical activity levels, physical activity types, Body Mass Index (BMI) and body fat percentage (BF%) values of elementary school students living in rural and urban. Body height (BH), body weight (BW), BF% and BMI data were measured. Physical activity questionnaire was conducted to determine the…

  3. Physical Activity and Body Mass Index

    Science.gov (United States)

    Nelson, Candace C.; Wagner, Gregory R.; Caban-Martinez, Alberto J.; Buxton, Orfeu M.; Kenwood, Christopher T.; Sabbath, Erika L.; Hashimoto, Dean M.; Hopcia, Karen; Allen, Jennifer; Sorensen, Glorian

    2014-01-01

    Background The workplace is an important domain for adults, and many effective interventions targeting physical activity and weight reduction have been implemented in the workplace. However, the U.S. workforce is aging and few studies have examined the relationship of BMI, physical activity, and age as they relate to workplace characteristics. Purpose This paper reports on the distribution of physical activity and BMI by age in a population of hospital-based healthcare workers and investigates the relationships among workplace characteristics, physical activity, and BMI. Methods Data from a survey of patient care workers in two large academic hospitals in the Boston area were collected in late 2009 and analyzed in early 2013. Results In multivariate models, workers reporting greater decision latitude (OR=1.02; 95% CI=1.01, 1.03) and job flexibility (OR=1.05; 95% CI=1.01, 1.10) reported greater physical activity. Overweight and obesity increased with age (p<0.01), even after adjusting for workplace characteristics. Sleep deficiency (OR=1.56; 95% CI=1.15, 2.12) and workplace harassment (OR= 1.62; 95% CI=1.20, 2.18) were also associated with obesity. Conclusions These findings underscore the persistent impact of the work environment for workers of all ages. Based on these results, programs or policies aimed at improving the work environment, especially decision latitude, job flexibility and workplace harassment should be included in the design of worksite-based health promotion interventions targeting physical activity or obesity. PMID:24512930

  4. Sedentary Activity and Body Composition of Middle School Girls: The Trial of Activity for Adolescent Girls

    Science.gov (United States)

    Pratt, Charlotte; Webber, Larry S.; Baggett, Chris D.; Ward, Dianne; Pate, Russell R.; Murray, David; Lohman, Timothy; Lytle, Leslie; Elder, John P.

    2008-01-01

    This study describes the relationships between sedentary activity and body composition in 1,458 sixth-grade girls from 36 middle schools across the United States. Multivariate associations between sedentary activity and body composition were examined with regression analyses using general linear mixed models. Mean age, body mass index, and…

  5. Space, body, time and relationship experiences of recess physical activity

    DEFF Research Database (Denmark)

    Pawlowski, Charlotte Skau; Andersen, Henriette Bondo; Tjørnhøj-Thomsen, Tine

    2016-01-01

    BACKGROUND: Increasing recess physical activity has been the aim of several interventions, as this setting can provide numerous physical activity opportunities. However, it is unclear if these interventions are equally effective for all children, or if they only appeal to children who are already...... the classroom as a space for physical activity, designing schoolyards with smaller secluded spaces and varied facilities, improving children's self-esteem and body image, e.g., during physical education, and creating teacher organised play activities during recess....

  6. Physical activity, body weight and cancer. Effects and methodology

    NARCIS (Netherlands)

    Steins Bisschop, C.N.

    2014-01-01

    Physical activity is an important determinant of general health, but seems to provide similar benefits after a diagnosis of disease, e.g. cancer. In this thesis, we investigated relations between physical activity, body weight and disease risk in the general population (Part I), and we studied some

  7. Whole-Body Listening: Developing Active Auditory Skills.

    Science.gov (United States)

    Truesdale, Susanne P.

    1990-01-01

    "Whole-body" activities are presented to teach first grade students what they must do to listen. The lesson plan covers the differences between hearing and listening, the active nature of listening, poor listening behaviors, and how teachers can tell who is a good listener. (JDD)

  8. Multichannel analysis of forward scattered body waves

    Science.gov (United States)

    Neal, Scott Lawrence

    We describe a series of innovations which are the basis for a multichannel approach to direct imaging of forward scattered body waves recorded on broadband seismic arrays. The foundation is a method through which the irregularly sampled observed seismograms are interpolated onto an arbitrarily fine grid by means of a convolution between a spatial window function and the actual station locations. The result is a weighted stack which employs all the data to compute a robust and stable multichannel estimate of the wavefield. Deconvolution of the stacked data is shown to be equivalent to a multichannel deconvolution, with spatially variable weights equal to those used in stacking. Application to data from the Lodore array in Colorado and Wyoming shows variations in crustal structure across the array and also images upper mantle discontinuities. A second innovation focuses on the design of deconvolution operators that account for the loss of high frequency components of P-to- S conversions. Two variants are presented, the first increases linearly with P-to-S lag time, the second is based on convolutional quelling and a t* attenuation model. Both methods account for the high attentuation of S waves in the upper mantle. The quelling approach however, has two advantages; it is physically based, and it provides a unified framework for the combination of stacking and deconvolution. We apply multichannel stacking to derive three quantities from the observed data and the associated receiver functions: (1) correlation between stacks of the entire array and local subarray stacks, (2) RMS amplitude of the receiver functions, and (3) Pms-to- P amplitude variations. Application of these attributes to data from recent broadband array deployments in southern Africa, Colorado and Wyoming, and the Tien Shan of central Asia shows these attributes to be highly correlated with the geology of the study areas and to be indicative of major lithospheric discontinuities beneath an array

  9. Active dehydration impairs upper and lower body anaerobic muscular power.

    Science.gov (United States)

    Jones, Leon C; Cleary, Michelle A; Lopez, Rebecca M; Zuri, Ron E; Lopez, Richard

    2008-03-01

    We examined the effects of active dehydration by exercise in a hot, humid environment on anaerobic muscular power using a test-retest (euhydrated and dehydrated) design. Seven subjects (age, 27.1 +/- 4.6 years; mass, 86.4 +/- 9.5 kg) performed upper and lower body Wingate anaerobic tests prior to and after a 1.5-hour recovery from a heat stress trial of treadmill exercise in a hot, humid environment (33.1 +/- 3.1C = 55.1 +/- 8.9% relative humidity) until a 3.1 +/- 0.3% body mass loss was achieved. Dehydration was confirmed by a significant body mass loss (P dehydrated compared to the euhydrated condition. Compared to the euhydrated condition, the dehydrated condition mean power was significantly (P = 0.014) decreased 7.17% in the upper body and 19.20% in the lower body. Compared to the euhydrated condition, the dehydrated condition peak power was significantly (P = 0.013) decreased 14.48% in the upper body and 18.36% in the lower body. No significant differences between the euhydrated and dehydrated conditions were found for decrease in power output (P = 0.219, power = 0.213). Our findings suggest that dehydration of 2.9% body mass decreases the ability to generate upper and lower body anaerobic power. Coaches and athletes must understand that sports performance requiring anaerobic strength and power can be impaired by inadequate hydration and may contribute to increased susceptibility to musculoskeletal injury.

  10. Active and passive stabilization of body pitch in insect flight.

    Science.gov (United States)

    Ristroph, Leif; Ristroph, Gunnar; Morozova, Svetlana; Bergou, Attila J; Chang, Song; Guckenheimer, John; Wang, Z Jane; Cohen, Itai

    2013-08-01

    Flying insects have evolved sophisticated sensory-motor systems, and here we argue that such systems are used to keep upright against intrinsic flight instabilities. We describe a theory that predicts the instability growth rate in body pitch from flapping-wing aerodynamics and reveals two ways of achieving balanced flight: active control with sufficiently rapid reactions and passive stabilization with high body drag. By glueing magnets to fruit flies and perturbing their flight using magnetic impulses, we show that these insects employ active control that is indeed fast relative to the instability. Moreover, we find that fruit flies with their control sensors disabled can keep upright if high-drag fibres are also attached to their bodies, an observation consistent with our prediction for the passive stability condition. Finally, we extend this framework to unify the control strategies used by hovering animals and also furnish criteria for achieving pitch stability in flapping-wing robots.

  11. Analysis and Modelling of Muscles Motion during Whole Body Vibration

    Directory of Open Access Journals (Sweden)

    La Gatta A

    2010-01-01

    Full Text Available The aim of the study is to characterize the local muscles motion in individuals undergoing whole body mechanical stimulation. In this study we aim also to evaluate how subject positioning modifies vibration dumping, altering local mechanical stimulus. Vibrations were delivered to subjects by the use of a vibrating platform, while stimulation frequency was increased linearly from 15 to 60 Hz. Two different subject postures were here analysed. Platform and muscles motion were monitored using tiny MEMS accelerometers; a contra lateral analysis was also presented. Muscle motion analysis revealed typical displacement trajectories: motion components were found not to be purely sinusoidal neither in phase to each other. Results also revealed a mechanical resonant-like behaviour at some muscles, similar to a second-order system response. Resonance frequencies and dumping factors depended on subject and his positioning. Proper mechanical stimulation can maximize muscle spindle solicitation, which may produce a more effective muscle activation.

  12. Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.

    Science.gov (United States)

    Schipper-Krom, Sabine; Juenemann, Katrin; Jansen, Anne H; Wiemhoefer, Anne; van den Nieuwendijk, Rianne; Smith, Donna L; Hink, Mark A; Bates, Gillian P; Overkleeft, Hermen; Ovaa, Huib; Reits, Eric

    2014-01-01

    Neurodegenerative disorders such as Huntington's disease are hallmarked by neuronal intracellular inclusion body formation. Whether proteasomes are irreversibly recruited into inclusion bodies in these protein misfolding disorders is a controversial subject. In addition, it has been proposed that the proteasomes may become clogged by the aggregated protein fragments, leading to impairment of the ubiquitin-proteasome system. Here, we show by fluorescence pulse-chase experiments in living cells that proteasomes are dynamically and reversibly recruited into inclusion bodies. As these recruited proteasomes remain catalytically active and accessible to substrates, our results challenge the concept of proteasome sequestration and impairment in Huntington's disease, and support the reported absence of proteasome impairment in mouse models of Huntington's disease.

  13. Mushroom bodies enhance initial motor activity in Drosophila.

    Science.gov (United States)

    Serway, Christine N; Kaufman, Rebecca R; Strauss, Roland; de Belle, J Steven

    2009-01-01

    The central body (or central complex, CCX) and the mushroom bodies (MBs) are brain structures in most insect phyla that have been shown to influence aspects of locomotion. The CCX regulates motor coordination and enhances activity while MBs have, thus far, been shown to suppress motor activity levels measured over time intervals ranging from hours to weeks. In this report, we investigate MB involvement in motor behavior during the initial stages (15 minutes) of walking in Buridan's paradigm. We measured aspects of walking in flies that had MB lesions induced by mutations in six different genes and by chemical ablation. All tested flies were later examined histologically to assess MB neuroanatomy. Mutant strains with MB structural defects were generally less active in walking than wild-type flies. Most mutants in which MBs were also ablated with hydroxyurea (HU) showed additional activity decrements. Variation in measures of velocity and orientation to landmarks among wild-type and mutant flies was attributed to pleiotropy, rather than to MB lesions. We conclude that MBs upregulate activity during the initial stages of walking, but suppress activity thereafter. An MB influence on decision making has been shown in a wide range of complex behaviors. We suggest that MBs provide appropriate contextual information to motor output systems in the brain, indirectly fine tuning walking by modifying the quantity (i.e., activity) of behavior.

  14. Analysis of the body composition of Paralympic athletes: Comparison of two methods.

    Science.gov (United States)

    Lemos, Valdir De Aquino; Alves, Eduardo Da Silva; Schwingel, Paulo Adriano; Rosa, João Paulo Pereira; Silva, Andressa Da; Winckler, Ciro; Vital, Roberto; De Almeida, Alexandre Aparecido; Tufik, Sergio; De Mello, Marco Túlio

    2016-11-01

    Body composition is a physiological variable associated with physical activity and, in some cases, is related to athletic performance. Our objectives were to describe the body composition of participants in three distinct Paralympic sports and to compare the values of body density and estimated body fat obtained from the Paralympic athletes on the National Team by air-displacement plethysmography (ADP) and by the anthropometric method (skinfolds (SFs)). The sample consisted of 70 volunteers of both genders. The body composition of the volunteers was evaluated using the ADP in a Bod Pod(®) and seven SFs. There were no significant differences between the values obtained by ADP and SF for body fat percentage (p = .58) and body density (p = .49). Analysis by Bland-Altman plots showed mean differences of 0.56 ± 4.94 (-9.12-10.23) and -0.0017 ± 0.0113 (-0.024-0.020) for body fat percentage and body density, respectively. In conclusion, body composition analyses of Paralympic athletes by the ADP and SF methods show similar results, and ADP should be used as the first option when available. When the use of ADP is not possible, estimating body density and fat percentage by SF is a viable alternative for Paralympic athletes when future comparisons will use the same analysis method.

  15. Multi-Body Dynamics and Modal Analysis of Compliant Gear Bodies

    Science.gov (United States)

    Vinayak, H.; Singh, R.

    1998-02-01

    This paper extends the multi-body dynamics modelling strategy for rigid gears to include compliant gear bodies in multi-mesh transmissions. Only external, fixed center, helical or spur gears are considered. This formulation combines distributed gear mesh stiffness and gear blank compliance models in a multi-body dynamics framework resulting in a set of non-linear differential equations with time-varying coefficients. Linearization and other simplifications are applied to yield the resulting linear time-invariant equations of motion. Several solution techniques are then used to determine eigensolutions and forced harmonic responses. The resulting normal mode solutions are compared to those obtained by the finite element analysis for several examples of transmission containing flexible gears. These include ring-gears and bodies with discontinuities. A parametric study has been performed to assess the effect of gear orientation on the dynamics of transmissions. Finally analytical predictions are compared to the results of a laboratory experiment.

  16. Body-Selective Areas in the Visual Cortex are less active in Children than in Adults

    Directory of Open Access Journals (Sweden)

    Paddy D Ross

    2014-11-01

    Full Text Available Our ability to read other people’s non-verbal signals gets refined throughout childhood and adolescence. How this is paralleled by brain development has been investigated mainly with regards to face perception, showing a protracted functional development of the face-selective visual cortical areas. In view of the importance of whole-body expressions in interpersonal communication it is important to understand the development of brain areas sensitive to these social signals.Here we used functional magnetic resonance imaging (fMRI to compare brain activity in a group of 24 children (age 6-11 and 26 adults while they passively watched short videos of body or object movements. We observed activity in similar regions in both groups; namely the extra-striate body area (EBA, fusiform body area (FBA, posterior superior temporal sulcus (pSTS, amygdala and premotor regions. Adults showed additional activity in the inferior frontal gyrus. Within the main body-selective regions (EBA, FBA and pSTS, the strength and spatial extent of fMRI signal change was larger in adults than in children. Multivariate Bayesian analysis showed that the spatial pattern of neural representation within those regions did not change over age.Our results indicate, for the first time, that body perception, like face perception, is still maturing through the second decade of life.

  17. Analysis of modal frequency optimization of railway vehicle car body

    Directory of Open Access Journals (Sweden)

    Wenjing Sun

    2016-04-01

    Full Text Available High structural modal frequencies of car body are beneficial as they ensure better vibration control and enhance ride quality of railway vehicles. Modal sensitivity optimization and elastic suspension parameters used in the design of equipment beneath the chassis of the car body are proposed in order to improve the modal frequencies of car bodies under service conditions. Modal sensitivity optimization is based on sensitivity analysis theory which considers the thickness of the body frame at various positions as variables in order to achieve optimization. Equipment suspension design analyzes the influence of suspension parameters on the modal frequencies of the car body through the use of an equipment-car body coupled model. Results indicate that both methods can effectively improve the modal parameters of the car body. Modal sensitivity optimization increases vertical bending frequency from 9.70 to 10.60 Hz, while optimization of elastic suspension parameters increases the vertical bending frequency to 10.51 Hz. The suspension design can be used without alteration to the structure of the car body while ensuring better ride quality.

  18. Light physical activity increased body fat percentage in elderly Javanese

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    Fatmah Fatmah

    2016-02-01

    Full Text Available The prevalence of obesity in Indonesia is rapidly increasing, particularly in older people. Obesity is characterized by increased percentage of body fat in the form of visceral fat and non-visceral or subcutaneous fat. The aim of this study was to analyze body fat percentage (BFP and associated risk factors, i.e. type of residence (rural or urban, physical activity, gender, age, intakes of energy and fat, and socio-economic background (educational level and occupational status. This cross-sectional study was conducted on 812 older persons (517 females and 295 males from December 2007- February 2008 in the cities of Surabaya, Semarang, Yogyakarta, Wonogiri, Gunung Kidul, and Magetan subdistricts. BFP was assessed using an Omron Fat Analyzer. Nutritional intakes were collected through interviews using semi-quantitative food frequency questionnaire (FFQ. To obtain overall total energy expenditure for physical activity (PA, the energy expenditures for exercise (sports PA, daily activities, and leisure time PA were added together. The study results indicated that urban residence and light PA at age 55 years constituted risk factors for high BFP. Light PA at 55 years of age was the most influential risk factor, since it was 4.3 times greater than vigorous PA at the same age (OR=4.3; 95% Confidence interval 2.6-7.1 It is recommended to implement nutritional counseling about adequate intakes for increased PA in all age groups (adolescents, adults, older persons, particularly in urban areas with their greater risk of high BFP.

  19. Body Composition, Physical Activity and Active Transportation in Adolescents of Metropolitan Region of Curitiba, Brazil

    Directory of Open Access Journals (Sweden)

    Leandra Ulbrict

    2014-06-01

    Full Text Available Background: Physical activity is a part of a healthy lifestyle, however sed entary habits are currently prevalent among adolescents which impacts rates of overweight and obesity in this group. This study aims to describe the relationship of physical activity with the use of active transportation to school (ATS and its relationshi p with body composition in adolescents. Materials and Methods: Information about physical activity, sedentary behavior and active transportation were collected through two survey instruments, one completed by a responsible parent/guardian and other by the adolescent. Body composition was assessed by dual - energy x - ray absorptiometry (DXA. Excess body fat was defined as ≥ 25% in male and ≥ 30% among female adolescents. Less than 60 minutes of moderate to vigorous daily physical activity defined one as sede ntary and greater than 2 hours of screen time per day was defined as excessive. Results: The prevalence of excess body fat was 46.5%. Only 24.7% of the sample performed recommended amounts of physical activity and 92.3% engaged in excess screen time. Appro ximately one - fifth of our sample (19.2% used ATS. The main barriers to active transport were traffic, distance and safety. Those that used ATS had lower body fat and fewer hours of sedentary behavior.

  20. Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

    Directory of Open Access Journals (Sweden)

    Bonnet Amandine

    2012-09-01

    Full Text Available Abstract Background The Tax protein encoded by Human T-lymphotropic virus type 1 (HTLV-1 is a powerful activator of the NF-κB pathway, a property critical for HTLV-1-induced immortalization of CD4+ T lymphocytes. Tax permanently stimulates this pathway at a cytoplasmic level by activating the IκB kinase (IKK complex and at a nuclear level by enhancing the binding of the NF-κB factor RelA to its cognate promoters and by forming nuclear bodies, believed to represent transcriptionally active structures. In previous studies, we reported that Tax ubiquitination and SUMOylation play a critical role in Tax localization and NF-κB activation. Indeed, analysis of lysine Tax mutants fused or not to ubiquitin or SUMO led us to propose a two-step model in which Tax ubiquitination first intervenes to activate IKK while Tax SUMOylation is subsequently required for promoter activation within Tax nuclear bodies. However, recent studies showing that ubiquitin or SUMO can modulate Tax activities in either the nucleus or the cytoplasm and that SUMOylated Tax can serve as substrate for ubiquitination suggested that Tax ubiquitination and SUMOylation may mediate redundant rather than successive functions. Results In this study, we analyzed the properties of a new Tax mutant that is properly ubiquitinated, but defective for both nuclear body formation and SUMOylation. We report that reducing Tax SUMOylation and nuclear body formation do not alter the ability of Tax to activate IKK, induce RelA nuclear translocation, and trigger gene expression from a NF-κB promoter. Importantly, potent NF-κB promoter activation by Tax despite low SUMOylation and nuclear body formation is also observed in T cells, including CD4+ primary T lymphocytes. Moreover, we show that Tax nuclear bodies are hardly observed in HTLV-1-infected T cells. Finally, we provide direct evidence that the degree of NF-κB activation by Tax correlates with the level of Tax ubiquitination, but not

  1. Influence of transaction costs on controlling activity of territorial taxation bodies

    Directory of Open Access Journals (Sweden)

    Natalya A. Bondareva

    2016-01-01

    Full Text Available Objective to disclose and justify transaction costs of controlling activities of the territorial taxation bodies and their impact on tax control under the need for effective functioning and optimal decision making with a view of reducing the state expenditures on tax control. Methods general scientific synthesis deduction induction generalization testing interviewing observation forecasting scientific abstraction statistical analysis logic and methods of grouping and classification expert assessment. Results the analysis and grouping of transaction costs of controlling activities of the territorial taxation bodies have been carried out. It was found that the most time and resource consuming are onsite tax inspections. The factors that have a significant impact on the efficiency of tax control were revealed. It is proved that the release of material and time resources contributes to the transformation of the tax bodies. Scientific novelty the main problem of implementation of the onsite tax control is its costs. The existing studies do not give a systematic list of tax control costs of the territorial tax bodies in general and transaction costs of tax control in particular. The author shows that the reduction of transaction costs as factors of influence on the tax control will free up the working time of the inspectors and will bring economic benefits and also will allow to consolidate territorial tax bodies and change the status of a tax inspector. Practical significance reducing the cost of tax control is becoming increasingly important in terms of saving financial resources of the state.

  2. Isolation of biologically active nanomaterial (inclusion bodies from bacterial cells

    Directory of Open Access Journals (Sweden)

    Peternel Špela

    2010-09-01

    Full Text Available Abstract Background In recent years bacterial inclusion bodies (IBs were recognised as highly pure deposits of active proteins inside bacterial cells. Such active nanoparticles are very interesting for further downstream protein isolation, as well as for many other applications in nanomedicine, cosmetic, chemical and pharmaceutical industry. To prepare large quantities of a high quality product, the whole bioprocess has to be optimised. This includes not only the cultivation of the bacterial culture, but also the isolation step itself, which can be of critical importance for the production process. To determine the most appropriate method for the isolation of biologically active nanoparticles, three methods for bacterial cell disruption were analyzed. Results In this study, enzymatic lysis and two mechanical methods, high-pressure homogenization and sonication, were compared. During enzymatic lysis the enzyme lysozyme was found to attach to the surface of IBs, and it could not be removed by simple washing. As this represents an additional impurity in the engineered nanoparticles, we concluded that enzymatic lysis is not the most suitable method for IBs isolation. During sonication proteins are released (lost from the surface of IBs and thus the surface of IBs appears more porous when compared to the other two methods. We also found that the acoustic output power needed to isolate the IBs from bacterial cells actually damages proteins structures, thereby causing a reduction in biological activity. High-pressure homogenization also caused some damage to IBs, however the protein loss from the IBs was negligible. Furthermore, homogenization had no side-effects on protein biological activity. Conclusions The study shows that among the three methods tested, homogenization is the most appropriate method for the isolation of active nanoparticles from bacterial cells.

  3. AMAB: Automated measurement and analysis of body motion

    NARCIS (Netherlands)

    Poppe, Ronald; Zee, van der Sophie; Heylen, Dirk K.J.; Taylor, Paul J.

    2014-01-01

    Technologies that measure human nonverbal behavior have existed for some time, and their use in the analysis of social behavior has become more popular following the development of sensor technologies that record full-body movement. However, a standardized methodology to efficiently represent and an

  4. Body mass index in Parkinson's disease: a meta-analysis.

    NARCIS (Netherlands)

    Marck, M.A. van der; Dicke, H.C.; Uc, E.Y.; Kentin, Z.H.; Borm, G.F.; Bloem, B.R.; Overeem, S.; Munneke, M.

    2012-01-01

    Prior work suggested that patients with Parkinson's disease (PD) have a lower Body Mass Index (BMI) than controls, but evidence is inconclusive. We therefore conducted a meta-analysis on BMI in PD. We searched MEDLINE, EMBASE, Cinahl and Scopus to identify cohort studies on BMI in PD, published befo

  5. Physical activity, body composition and metabolic syndrome in young adults.

    Directory of Open Access Journals (Sweden)

    Minna K Salonen

    Full Text Available Low physical activity (PA is a major risk factor for cardiovascular and metabolic disorders in all age groups. We measured intensity and volume of PA and examined the associations between PA and the metabolic syndrome (MS, its components and body composition among young Finnish adults.The study comprises 991 men and women born 1985-86, who participated in a clinical study during the years 2009-11 which included assessments of metabolism, body composition and PA. Objectively measured (SenseWear Armband five-day PA data was available from 737 participants and was expressed in metabolic equivalents of task (MET.The prevalence of MS ranged between 8-10%. Higher total mean volume (MET-hours or intensity (MET were negatively associated with the risk of MS and separate components of MS, while the time spent at sedentary level of PA was positively associated with MS.MS was prevalent in approximately every tenth of the young adults at the age of 24 years. Higher total mean intensity and volume rates as well as longer duration spent at moderate and vigorous PA level had a beneficial impact on the risk of MS. Longer time spent at the sedentary level of PA increased the risk of MS.

  6. Modeling for Deformable Body and Motion Analysis: A Review

    Directory of Open Access Journals (Sweden)

    Hailang Pan

    2013-01-01

    Full Text Available This paper surveys the modeling methods for deformable human body and motion analysis in the recent 30 years. First, elementary knowledge of human expression and modeling is introduced. Then, typical human modeling technologies, including 2D model, 3D surface model, and geometry-based, physics-based, and anatomy-based approaches, and model-based motion analysis are summarized. Characteristics of these technologies are analyzed. The technology accumulation in the field is outlined for an overview.

  7. Effect of Physical Activity on BMI and Percent Body Fat of Chinese Girls.

    Science.gov (United States)

    Fu, Frank H.; And Others

    1995-01-01

    This study investigated the effect of regular physical activity on body mass index (BMI) and percent body fat of Chinese girls grouped by age and physical activity patterns. Measurements of skinfold, height, and weight, and BMI calculations, found differences in BMI and percent body fat between active and inactive girls. (SM)

  8. Body fluid identification by integrated analysis of DNA methylation and body fluid-specific microbial DNA.

    Science.gov (United States)

    Choi, Ajin; Shin, Kyoung-Jin; Yang, Woo Ick; Lee, Hwan Young

    2014-01-01

    Identification of body fluids found at crime scenes provides important information that can support a link between sample donors and actual criminal acts. Previous studies have reported that DNA methylation analysis at several tissue-specific differentially methylated regions (tDMRs) enables successful identification of semen, and the detection of certain bacterial DNA can allow for identification of saliva and vaginal fluid. In the present study, a method for detecting bacterial DNA was integrated into a previously reported multiplex methylation-sensitive restriction enzyme-polymerase chain reaction. The developed multiplex PCR was modified by the addition of a new semen-specific marker and by including amplicons for the 16S ribosomal RNA gene of saliva- and vaginal fluid-specific bacteria to improve the efficacy to detect a specific type of body fluid. Using the developed multiplex system, semen was distinguishable by unmethylation at the USP49, DACT1, and PFN3 tDMRs and by hypermethylation at L81528, and saliva could be identified by detection of saliva-specific bacteria, Veillonella atypica and/or Streptococcus salivarius. Additionally, vaginal fluid and menstrual blood were differentiated from other body fluids by hypomethylation at the PFN3 tDMR and the presence of vaginal fluid-specific bacteria, Lactobacillus crispatus and/or Lactobacillus gasseri. Because the developed multiplex system uses the same biological source of DNA for individual identification profiling and simultaneously analyses various types of body fluid in one PCR reaction, this method will facilitate more efficient body fluid identification in forensic casework.

  9. Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies

    NARCIS (Netherlands)

    Schipper-Krom, S.; Juenemann, K.; Jansen, A.H.; Wiemhoefer, A.; van den Nieuwendijk, R.; Smith, D.L.; Hink, M.A.; Bates, G.P.; Overkleeft, H.; Ovaa, H.; Reits, E.

    2014-01-01

    Neurodegenerative disorders such as Huntington's disease are hallmarked by neuronal intracellular inclusion body formation. Whether proteasomes are irreversibly recruited into inclusion bodies in these protein misfolding disorders is a controversial subject. In addition, it has been proposed that th

  10. Mid-L/D Lifting Body Entry Demise Analysis

    Science.gov (United States)

    Ling, Lisa

    2017-01-01

    The mid-lift-to-drag ratio (mid-L/D) lifting body is a fully autonomous spacecraft under design at NASA for enabling a rapid return of scientific payloads from the International Space Station (ISS). For contingency planning and risk assessment for the Earth-return trajectory, an entry demise analysis was performed to examine three potential failure scenarios: (1) nominal entry interface conditions with loss of control, (2) controlled entry at maximum flight path angle, and (3) controlled entry at minimum flight path angle. The objectives of the analysis were to predict the spacecraft breakup sequence and timeline, determine debris survival, and calculate the debris dispersion footprint. Sensitivity analysis was also performed to determine the effect of the initial pitch rate on the spacecraft stability and breakup during the entry. This report describes the mid-L/D lifting body and presents the results of the entry demise and sensitivity analyses.

  11. Structural analysis of the JT-60SA cryostat vessel body

    Energy Technology Data Exchange (ETDEWEB)

    Botija, José, E-mail: jose.botija@ciemat.es [Association EURATOM – CIEMAT, Avda. Complutense 40, 28040 Madrid (Spain); Alonso, Javier; Fernández, Pilar; Medrano, Mercedes; Ramos, Francisco; Rincon, Esther; Soleto, Alfonso [Association EURATOM – CIEMAT, Avda. Complutense 40, 28040 Madrid (Spain); Davis, Sam; Di Pietro, Enrico; Tomarchio, Valerio [Fusion for Energy, JT-60SA European Home Team, 85748 Garching bei Munchen (Germany); Masaki, Kei; Sakasai, Akira; Shibama, Yusuke [JAEA – Japan Atomic Energy Agency, Naka Fusion Institute, Ibaraki 311-0193 (Japan)

    2013-10-15

    Highlights: ► Structural analysis to validate the JT-60SA cryostat vessel body design. ► Design code ASME 2007 “Boiler and Pressure Vessel Code. Section VIII”. ► First buckling mode: load multiplier of 10.644, higher than the minimum factor 4.7. ► Elastic and elastic–plastic stress analysis meets ASME against plastic collapse. ► Bolted fasteners have been analyzed showing small gaps closed by strong welding. -- Abstract: The JT-60SA cryostat is a stainless steel vacuum vessel (14 m diameter, 16 m height) which encloses the Tokamak providing the vacuum environment (10{sup −3} Pa) necessary to limit the transmission of thermal loads to the components at cryogenic temperature. It must withstand both external atmospheric pressure during normal operation and internal overpressure in case of an accident. The paper summarizes the structural analyses performed in order to validate the JT-60SA cryostat vessel body design. It comprises several analyses: a buckling analysis to demonstrate stability under the external pressure; an elastic and an elastic–plastic stress analysis according to ASME VIII rules, to evaluate resistance to plastic collapse including localized stress concentrations; and, finally, a detailed analysis with bolted fasteners in order to evaluate the behavior of the flanges, assuring the integrity of the vacuum sealing welds of the cryostat vessel body.

  12. Developmental quantitative genetic analysis of body weights and morphological traits in the turbot, Scophthalmusmaximus

    Institute of Scientific and Technical Information of China (English)

    WANG Xinan; MA Aijun; MA Deyou

    2015-01-01

    In order to elucidate the genetic mechanism of growth traits in turbot during ontogeny, developmental genetic analysis of the body weights, total lengths, standard lengths and body heights of turbots was conducted by mixed genetic models with additive-dominance effects, based on complete diallel crosses with four different strains of Scophthalmus maximus from Denmark, Norway, Britain, and France. Unconditional genetic analysis revealed that the unconditional additive effects for the four traits were more significant than unconditional dominance effects, meanwhile, the alternative expressions were also observed between the additive and dominant effects for body weights, total lengths and standard lengths. Conditional analysis showed that the developmental periods with active gene expression for body weights, total lengths, standard lengths and body heights were 15–18, 15 and 21–24, 15 and 24, and 21 and 27 months of age, respectively. The proportions of unconditional/conditional variances indicated that the narrow-sense heritabilities of body weights, total lengths and standard lengths were all increased systematically. The accumulative effects of genes controlling the four quantitative traits were mainly additive effects, suggesting that the selection is more efficient for the genetic improvement of turbots. The conditional genetic procedure is a useful tool to understand the expression of genes controlling developmental quantitative traits at a specific developmental period (t-1→t) during ontogeny. It is also important to determine the appropriate developmental period (t-1→t) for trait measurement in developmental quantitative genetic analysis in fish.

  13. Attribution of emotions to body postures: an independent component analysis study of functional connectivity in autism.

    Science.gov (United States)

    Libero, Lauren E; Stevens, Carl E; Kana, Rajesh K

    2014-10-01

    The ability to interpret others' body language is a vital skill that helps us infer their thoughts and emotions. However, individuals with autism spectrum disorder (ASD) have been found to have difficulty in understanding the meaning of people's body language, perhaps leading to an overarching deficit in processing emotions. The current fMRI study investigates the functional connectivity underlying emotion and action judgment in the context of processing body language in high-functioning adolescents and young adults with autism, using an independent components analysis (ICA) of the fMRI time series. While there were no reliable group differences in brain activity, the ICA revealed significant involvement of occipital and parietal regions in processing body actions; and inferior frontal gyrus, superior medial prefrontal cortex, and occipital cortex in body expressions of emotions. In a between-group analysis, participants with autism, relative to typical controls, demonstrated significantly reduced temporal coherence in left ventral premotor cortex and right superior parietal lobule while processing emotions. Participants with ASD, on the other hand, showed increased temporal coherence in left fusiform gyrus while inferring emotions from body postures. Finally, a positive predictive relationship was found between empathizing ability and the brain areas underlying emotion processing in ASD participants. These results underscore the differential role of frontal and parietal brain regions in processing emotional body language in autism.

  14. Lidar point density analysis: implications for identifying water bodies

    Science.gov (United States)

    Worstell, Bruce B.; Poppenga, Sandra; Evans, Gayla A.; Prince, Sandra

    2014-01-01

    Most airborne topographic light detection and ranging (lidar) systems operate within the near-infrared spectrum. Laser pulses from these systems frequently are absorbed by water and therefore do not generate reflected returns on water bodies in the resulting void regions within the lidar point cloud. Thus, an analysis of lidar voids has implications for identifying water bodies. Data analysis techniques to detect reduced lidar return densities were evaluated for test sites in Blackhawk County, Iowa, and Beltrami County, Minnesota, to delineate contiguous areas that have few or no lidar returns. Results from this study indicated a 5-meter radius moving window with fewer than 23 returns (28 percent of the moving window) was sufficient for delineating void regions. Techniques to provide elevation values for void regions to flatten water features and to force channel flow in the downstream direction also are presented.

  15. Multi-Body Analysis of a Tiltrotor Configuration

    Science.gov (United States)

    Ghiringhelli, G. L.; Masarati, P.; Mantegazza, P.; Nixon, M. W.

    1997-01-01

    The paper describes the aeroelastic analysis of a tiltrotor configuration. The 1/5 scale wind tunnel semispan model of the V-22 tiltrotor aircraft is considered. The analysis is performed by means of a multi-body code, based on an original formulation. The differential equilibrium problem is stated in terms of first order differential equations. The equilibrium equations of every rigid body are written, together with the definitions of the momenta. The bodies are connected by kinematic constraints, applied in form of Lagrangian multipliers. Deformable components are mainly modelled by means of beam elements, based on an original finite volume formulation. Multi-disciplinar problems can be solved by adding user-defined differential equations. In the presented analysis the equations related to the control of the swash-plate of the model are considered. Advantages of a multi-body aeroelastic code over existing comprehensive rotorcraft codes include the exact modelling of the kinematics of the hub, the detailed modelling of the flexibility of critical hub components, and the possibility to simulate steady flight conditions as well as wind-up and maneuvers. The simulations described in the paper include: 1) the analysis of the aeroelastic stability, with particular regard to the proprotor/pylon instability that is peculiar to tiltrotors, 2) the determination of the dynamic behavior of the system and of the loads due to typical maneuvers, with particular regard to the conversion from helicopter to airplane mode, and 3) the stress evaluation in critical components, such as the pitch links and the conversion downstop spring.

  16. THE RESULTS OF THE ANALYSIS OF THE STUDENTS’ BODY COMPOSITION BY BIOIMPEDANCE METHOD

    Directory of Open Access Journals (Sweden)

    Dmitry S. Blinov

    2016-06-01

    Full Text Available Introduction. Tissues of the human body can conduct electricity. Liquid medium (water, blood, the contents of hollow bodies, have a low impedance, i.e. good conductors, while denser tissue (muscle, nerves, etc. resistance is significantly higher. The biggest impedance have fat and bone tissues. The bioimpendancemetry – a method which allows to determine the composition of the human body by measuring electrical resistance (impedance of its tissues. Relevance. This technique is indispensable to dieticians and fitness trainers. In addition, the results of the study can provide invaluable assistance in the appointment of effective treatment physicians, gynecologists, orthopedists, and other specialists. The bioimpedance method helps to determine the risks of developing diabetes type 2, atherosclerosis, hypertension, diseases of the musculoskeletal system, disorders of the endocrine system, gall-stone disease and etc. Materials and Methods. In the list of parameters of body composition assessed by bioimpedance analysis method, included absolute and relative indicators. Depending on the method of measurement of the absolute rates were determined for the whole body. To absolute performance were: fat and skinny body mass index, active cell and skeletal muscle mass, total body water, cellular and extracellular fluid. Along with them were calculated relatively (normalized to body weight, lean mass, or other variables indicators of body composition. Results. In the result of the comparison of anthropometric and bioimpedance method found that growth performance, vital capacity, weight, waist circumference, circumfer¬ence of waist and hip, basal metabolism, body fat mass, normalized on growth, lean mass, percentage skeletal muscle mass in boys and girls with normal and excessive body weight had statistically significant differences. Discussion and Conclusions. In the present study physical development with consideration of body composition in students

  17. Naive Dimensional Analysis for Three-Body Forces Without Pions

    CERN Document Server

    Griesshammer, H W

    2005-01-01

    For systems of three identical particles in which short-range forces produce shallow two-particle bound states, and in particular for the ``pion-less'' Effective Field Theory of Nuclear Physics, I extend and systematise the power-counting of three-body forces to all partial-waves and orders, including external currents. With low-energy observables independent of the details of short-distance dynamics, the typical strength of a three-body force is determined from the superficial degree of divergence of the three-body diagrams which contain only two-body forces. This na\\"ive dimensional analysis must be amended as the asymptotic solution to the leading-order Faddeev equation depends for large off-shell momenta crucially on the partial wave and spin-combination of the system. It is shown by analytic construction to be weaker in most channels with angular momentum smaller than 3 than expected. This demotes many three-nucleon forces to high orders. Observables like the quartet-S-scattering length are less sensitiv...

  18. Physical activity, body weight, and resumption of menses in anorexia nervosa.

    Science.gov (United States)

    El Ghoch, Marwan; Calugi, Simona; Pellegrini, Massimo; Chignola, Elisa; Dalle Grave, Riccardo

    2016-12-30

    Few data are available on long-term outcomes and increased physical activity at the end of inpatient treatment in patients with anorexia nervosa. Hence we assessed the association between physical activity, measured objectively by Sense Wear Armband (SWA), and body mass index (BMI; kg/m(2)) and menses resumption at one-year follow-up in 32 females with anorexia nervosa who had restored normal body weight by the end of a specialist inpatient treatment. Combined logistic regression models used to evaluate the relationship between variables at discharge, BMI and resumption of menses at one-year follow-up revealed no significant association between BMI at one-year follow-up and physical activity patterns at inpatient discharge. However, total daily steps at inpatient discharge were significantly lower in patients who had resumed menstruation, as confirmed by logistic regression analysis. A small reduction in daily steps at inpatient discharge (~1000 steps) was found to increase the probability of menses resumption at one-year follow-up by ~3%. These data provide preliminary indications as to the potential usefulness of assessing daily steps to predict the resumption of menses at one-year follow-up in patients with anorexia nervosa who restore body weight by the end of inpatient treatment, although confirmation on larger samples is urgently required.

  19. Enabling Large-body Active Debris Removal Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Research suggests that: (1) orbital debris has reached the point that, even with no future launches, collisions among large-body debris will lead to unstable growth...

  20. Context-Aware Active Authentication using Touch Gestures, Typing Patterns and Body Movement

    Science.gov (United States)

    2016-03-01

    15. SUBJECT TERMS Active Authentication, behavioral biometrics, keystroke dynamics 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU...CONTEXT-AWARE ACTIVE AUTHENTICATION USING TOUCH GESTURES, TYPING PATTERNS, AND BODY MOVEMENT LOUISIANA TECH UNIVERSITY MARCH 2016...TITLE AND SUBTITLE Context-Aware Active Authentication using Touch Gestures, Typing Patterns, and Body Movement 5a. CONTRACT NUMBER FA8750-13-2

  1. Lyapunov vs. geometrical stability analysis of the Kepler and the restricted three body problems

    DEFF Research Database (Denmark)

    Yahalom, A.; Levitan, J.; Lewkowicz, M.

    2011-01-01

    of the standard Lyapunov analysis and the strength of the geometrical analysis. Moreover, we apply this approach to the three body problem in which the third body is restricted to move on a circle of large radius which induces an adiabatic time dependent potential on the second body. This causes the second body...

  2. Fuzzy cluster analysis of the provenance of ancient Yaozhou porcelain body

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The technique of neutron activation analysis (NAA) has been employed to measure the content of 29 kinds of elements in the sample of Yaozhou porcelain bodies. Then a fuzzy cluster analysis has been conducted to the NAA data and a diagram of the dynamic fuzzy cluster analysis has been achieved. The results indicate that the batch of ancient Yaozhou porcelain bodies, which were of different overglaze color and were produced by different kilns during a period of over 800 years from the Tang Dynasty (618-907 A.D.) to the Yuan Dynasty (1271-1368 A.D.), has shared a stable and concentrated raw material source. Provenances of porcelain bodies from different times, though having their specific independence, enjoy a close relationship and are not far from one another. Provenances of porcelain bodies made during the Tang Dynasty and the Five Dynasties (907-960 A.D.) are found to be closer to one another, while those of the Song (960-1279 A.D.) and the Jin Dynasty (1115-1234 A.D.) are comparatively concentrated in certain areas and are different from those of the Tang Dynasty. Both the tri-colored glazed pottery made in Yaozhou kilns during the Tang Dynasty and the Yaozhou porcelain bodies of the Tang period are from the same provenance.

  3. Improved Aerodynamic Analysis for Hybrid Wing Body Conceptual Design Optimization

    Science.gov (United States)

    Gern, Frank H.

    2012-01-01

    This paper provides an overview of ongoing efforts to develop, evaluate, and validate different tools for improved aerodynamic modeling and systems analysis of Hybrid Wing Body (HWB) aircraft configurations. Results are being presented for the evaluation of different aerodynamic tools including panel methods, enhanced panel methods with viscous drag prediction, and computational fluid dynamics. Emphasis is placed on proper prediction of aerodynamic loads for structural sizing as well as viscous drag prediction to develop drag polars for HWB conceptual design optimization. Data from transonic wind tunnel tests at the Arnold Engineering Development Center s 16-Foot Transonic Tunnel was used as a reference data set in order to evaluate the accuracy of the aerodynamic tools. Triangularized surface data and Vehicle Sketch Pad (VSP) models of an X-48B 2% scale wind tunnel model were used to generate input and model files for the different analysis tools. In support of ongoing HWB scaling studies within the NASA Environmentally Responsible Aviation (ERA) program, an improved finite element based structural analysis and weight estimation tool for HWB center bodies is currently under development. Aerodynamic results from these analyses are used to provide additional aerodynamic validation data.

  4. AN ANALYSIS OF 3D FINITE CRACKED BODIES

    Institute of Scientific and Technical Information of China (English)

    Tao Weiming; Guo Yimu; Cao Zhiyuan

    2001-01-01

    The new-type traction boundary integral equations developed by Hu and with no hyper singular integral are applied to analysis of 3D finite cracked bodies. A numerical algorithm for general 3D problems and a semi-analytical one for axisymmetric problems are presented. Some examples of thick plates and cylindrical columns including penny-shaped crack(s), and rectangular plates including an elliptical crack normal to the surface are analyzed. The comparison between present results and those in literature shows the high accuracy and effectiveness of the present method.

  5. Analysis of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Wu, Hsi-Yung T.; Shaw, Peter; Przekop, Adam

    2013-01-01

    The hybrid wing body center section test article is an all-composite structure made of crown, floor, keel, bulkhead, and rib panels utilizing the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) design concept. The primary goal of this test article is to prove that PRSEUS components are capable of carrying combined loads that are representative of a hybrid wing body pressure cabin design regime. This paper summarizes the analytical approach, analysis results, and failure predictions of the test article. A global finite element model of composite panels, metallic fittings, mechanical fasteners, and the Combined Loads Test System (COLTS) test fixture was used to conduct linear structural strength and stability analyses to validate the specimen under the most critical combination of bending and pressure loading conditions found in the hybrid wing body pressure cabin. Local detail analyses were also performed at locations with high stress concentrations, at Tee-cap noodle interfaces with surrounding laminates, and at fastener locations with high bearing/bypass loads. Failure predictions for different composite and metallic failure modes were made, and nonlinear analyses were also performed to study the structural response of the test article under combined bending and pressure loading. This large-scale specimen test will be conducted at the COLTS facility at the NASA Langley Research Center.

  6. Numeric calculation of celestial bodies with spreadsheet analysis

    Science.gov (United States)

    Koch, Alexander

    2016-04-01

    The motion of the planets and moons in our solar system can easily be calculated for any time by the Kepler laws of planetary motion. The Kepler laws are a special case of the gravitational law of Newton, especially if you consider more than two celestial bodies. Therefore it is more basic to calculate the motion by using the gravitational law. But the problem is, that by gravitational law it is not possible to calculate the state of motion with only one step of calculation. The motion has to be numerical calculated for many time intervalls. For this reason, spreadsheet analysis is helpful for students. Skills in programmes like Excel, Calc or Gnumeric are important in professional life and can easily be learnt by students. These programmes can help to calculate the complex motions with many intervalls. The more intervalls are used, the more exact are the calculated orbits. The sutdents will first get a quick course in Excel. After that they calculate with instructions the 2-D-coordinates of the orbits of Moon and Mars. Step by step the students are coding the formulae for calculating physical parameters like coordinates, force, acceleration and velocity. The project is limited to 4 weeks or 8 lessons. So the calcualtion will only include the calculation of one body around the central mass like Earth or Sun. The three-body problem can only be shortly discussed at the end of the project.

  7. Optical Signature Analysis of Tumbling Rocket Bodies via Laboratory Measurements

    Science.gov (United States)

    Cowardin, H.; Lederer, S.; Liou, J.-C.

    2012-01-01

    The NASA Orbital Debris Program Office has acquired telescopic lightcurve data on massive intact objects, specifically spent rocket bodies, in order to ascertain tumble rates in support of the Active Debris Removal (ADR) task to help remediate the LEO environment. Rotation rates are needed to plan and develop proximity operations for potential future ADR operations. To better characterize and model optical data acquired from ground-based telescopes, the Optical Measurements Center (OMC) at NASA/JSC emulates illumination conditions in space using equipment and techniques that parallel telescopic observations and source-target-sensor orientations. The OMC employs a 75-watt Xenon arc lamp as a solar simulator, an SBIG CCD camera with standard Johnson/Bessel filters, and a robotic arm to simulate an object's position and rotation. The light source is mounted on a rotary arm, allowing access any phase angle between 0 -- 360 degrees. The OMC does not attempt to replicate the rotation rates, but focuses on how an object is rotating as seen from multiple phase angles. The two targets studied are scaled (1:48), SL-8 Cosmos 3M second stages. The first target is painted in the standard government "gray" scheme and the second target is primary white, as used for commercial missions. This paper summarizes results of the two scaled rocket bodies, each rotated about two primary axes: (a) a spin-stabilized rotation and (b) an end-over-end rotation. The two rotation states are being investigated as a basis for possible spin states of rocket bodies, beginning with simple spin states about the two primary axes. The data will be used to create a database of potential spin states for future works to convolve with more complex spin states. The optical signatures will be presented for specific phase angles for each rocket body and shown in conjunction with acquired optical data from multiple telescope sources.

  8. Sugar intake, soft drink consumption and body weight among British children: further analysis of National Diet and Nutrition Survey data with adjustment for under-reporting and physical activity.

    Science.gov (United States)

    Gibson, Sigrid; Neate, Deborah

    2007-09-01

    We investigated associations between body mass index (BMI) and intake of non-milk extrinsic sugars (NMES) and caloric soft drinks using weighed 7-day food records, nutrient intakes, BMI measurements and 7-day physical activity (PA) diaries from the UK National Dietary and Nutritional Survey of Young People (n=1,294 aged 7-18 years). NMES and caloric soft drinks (excluding 100% fruit juice) were quantified by their contribution to energy intake. BMI z-scores were calculated from UK reference curves and International Obesity Task Force (IOTF) cut-off values were used to define overweight. The BMI z-score was weakly inversely correlated with percentage energy from NMES after adjustment for under-reporting and dieting (r=-0.06, P=0.03). The percentage of energy from soft drinks was not associated with the BMI z-score or PA. After excluding under-reporters and dieters, the heaviest children (top quintile: Q5 of BMI z-scores) consumed more total energy (+1,220 kJ/day) than those in the lowest quintile (Q1), but only 60 kJ (5%) was from soft drinks. In logistic regression (adjusted for age and gender, under-reporting, and dieting), overweight was positively associated with energy intake (MJ) (odds ratio [OR]=1.58, confidence interval [CI]=1.42-1.77) and sedentary activity (h) (OR=1.11, CI=1.01-1.23), and inversely associated with moderate/vigorous activity (h) (OR=0.71, CI=0.58-0.86). In the macronutrient model, high fat and protein intake (top tertile vs lowest tertile, g/day) were positively associated with overweight (OR>2.5, Psoft drinks were weakly associated with overweight (OR=1.39, CI=0.96-2.0, P=0.08), while other sources of NMES showed no association (OR=0.81, CI=0.52-1.27, P=0.4). Risk associated with caloric soft drinks appeared non-linear with an increase in odds only for very high consumers (top quintile, mean 870 kJ/day; OR=1.67, CI=1.04-2.66, P=0.03). These data are not consistent with any specific role for NMES or caloric soft drinks in obesity among

  9. Phosphoproteomic analysis of the Chlamydia caviae elementary body and reticulate body forms.

    Science.gov (United States)

    Fisher, Derek J; Adams, Nancy E; Maurelli, Anthony T

    2015-08-01

    Chlamydia are Gram-negative, obligate intracellular bacteria responsible for significant diseases in humans and economically important domestic animals. These pathogens undergo a unique biphasic developmental cycle transitioning between the environmentally stable elementary body (EB) and the replicative intracellular reticulate body (RB), a conversion that appears to require extensive regulation of protein synthesis and function. However, Chlamydia possess a limited number of canonical mechanisms of transcriptional regulation. Ser/Thr/Tyr phosphorylation of proteins in bacteria has been increasingly recognized as an important mechanism of post-translational control of protein function. We utilized 2D gel electrophoresis coupled with phosphoprotein staining and MALDI-TOF/TOF analysis to map the phosphoproteome of the EB and RB forms of Chlamydia caviae. Forty-two non-redundant phosphorylated proteins were identified (some proteins were present in multiple locations within the gels). Thirty-four phosphorylated proteins were identified in EBs, including proteins found in central metabolism and protein synthesis, Chlamydia-specific hypothetical proteins and virulence-related proteins. Eleven phosphorylated proteins were identified in RBs, mostly involved in protein synthesis and folding and a single virulence-related protein. Only three phosphoproteins were found in both EB and RB phosphoproteomes. Collectively, 41 of 42 C. caviae phosphoproteins were present across Chlamydia species, consistent with the existence of a conserved chlamydial phosphoproteome. The abundance of stage-specific phosphoproteins suggests that protein phosphorylation may play a role in regulating the function of developmental-stage-specific proteins and/or may function in concert with other factors in directing EB-RB transitions.

  10. A numerical analysis of the unsteady flow past bluff bodies

    Science.gov (United States)

    Fernando, M. S. U. K.; Modi, V. J.

    1990-01-01

    The paper describes in detail a relatively sophisticated numerical approach, using the Boundary Element Method in conjunction with the Discrete Vortex Model, to represent the complex unsteady flow field around a bluff body with separating shear layers. Important steps in the numerical analysis of this challenging problem are discussed and a performance evaluation algorithm established. Of considerable importance is the effect of computational parameters such as number of elements representing the geometry, time-step size, location of the nascent vortices, etc., on the accuracy of results and the associated cost. As an example, the method is applied to the analysis of the flow around a stationary Savonius rotor. A detailed parametric study provides fundamental information concerning the starting torque time histories, evolution of the wake, Strouhal number, etc. A comparison with the wind tunnel test data shows remarkable correlation suggesting considerable promise for the approach.

  11. Physical activity and bone mineral accrual in boys with different body mass parameters during puberty: a longitudinal study.

    Directory of Open Access Journals (Sweden)

    Donvina Vaitkeviciute

    Full Text Available The aim of our longitudinal study was to investigate the relationships between physical activity and bone mass in boys with different body mass status during the years surrounding pubertal growth spurt. Two hundred and six boys entering puberty took part in this study. The subjects were divided into underweight (BMI 26.02 groups at baseline according to age related categories. Whole-body DXA scans were performed at baseline, after 12 and 24 months to assess body composition (lean body mass, fat mass, and total body (TB, lumbar spine (LS and femoral neck (FN bone mineral density (BMD parameters. Physical activity was measured by 7-day accelerometry. For longitudinal analysis, multilevel fixed effects regression models were constructed. Biological age, height and lean body mass had an effect for explanation of TB BMD, FN BMD and LS BMD. Moderate to vigorous physical activity (MVPA, vigorous physical activity (VPA and sedentary time (SED had the significant effect only on FN BMD. Being an underweight boy at the baseline indicated greater chance (p<0.01 to have lower TB BMD in the future (2 years at follow up development, compared to normal weight (estimates = -0.038, overweight (estimates = -0.061 and obese boys (estimates = -0.106.

  12. A Hierarchical Approach to Real-time Activity Recognition in Body Sensor Networks

    DEFF Research Database (Denmark)

    Wang, Liang; Gu, Tao; Tao, Xianping

    2012-01-01

    Real-time activity recognition in body sensor networks is an important and challenging task. In this paper, we propose a real-time, hierarchical model to recognize both simple gestures and complex activities using a wireless body sensor network. In this model, we rst use a fast and lightweight al...

  13. Body composition of active persons with spinal cord injury and with poliomyelitis

    Science.gov (United States)

    This study sought to evaluate the body composition of subjects with active spinal cord injuries and polio. Two groups of males and females, active, free-living, of similar ages and body mass index (BMI), were distributed according to the source of deficiency: SCI – low spinal cord injury (T5-T12) an...

  14. The effect of active video gaming on children's physical activity, behavior preferences and body composition.

    Science.gov (United States)

    Graves, Lee E F; Ridgers, Nicola D; Atkinson, Greg; Stratton, Gareth

    2010-11-01

    Active video game interventions typically provide children a single game that may become unappealing. A peripheral device (jOG) encourages step-powered gaming on multiple games. This trial evaluated the effect of jOG on children's objectively measured PA, body fat and self-reported behaviors. 42 of 58 eligible children (8-10 y) randomly assigned to an intervention (jOG) or control (CON) completed the trial. Intervention children received two jOG devices for home use. Analyses of covariance compared the intervention effect at 6 and 12 weeks from baseline. No differences were found between groups for counts per minute (CPM; primary outcome) at 6 and 12 weeks (p > .05). Active video gaming increased (adjusted change 0.95 (95% CI 0.25, 1.65) h·d⁻¹, p .05) at 6 weeks relative to CON. No body fat changes were observed between groups. Targeted changes in video game use did not positively affect PA. Larger trials are needed to verify the impact of active video games on children's PA and health.

  15. Body fat related to daily physical activity and insulin concentrations in non-diabetic children

    DEFF Research Database (Denmark)

    Dencker, Magnus; Thorsson, Ola; Karlsson, Magnus K

    2007-01-01

    This study explored the associations between body fat versus daily physical activity and insulin concentrations in non-diabetic young children in a cross-sectional study of 172 children (93 boys and 79 girls) aged 8-11 years. Blood samples were analysed for serum insulin and daily physical activity...... was measured by accelerometers. Time spent performing vigorous activity was estimated from accelerometer data by using established cut-off points. Dual-energy x-ray absorptiometry (DXA) was used to quantify abdominal fat mass (AFM) and total body fat (TBF), also calculated as percentage of body weight (BF......%). Body fat distribution was calculated as AFM/TBF. Body fat distribution was independently linked to both insulin concentrations and physical activity. In contrast, TBF, AFM, and BF% were linked to physical activity only and not to insulin concentrations. In conclusion in this population of non...

  16. Dissection of human vitreous body elements for proteomic analysis.

    Science.gov (United States)

    Skeie, Jessica M; Mahajan, Vinit B

    2011-01-23

    The vitreous is an optically clear, collagenous extracellular matrix that fills the inside of the eye and overlies the retina. (1,2) Abnormal interactions between vitreous substructures and the retina underlie several vitreoretinal diseases, including retinal tear and detachment, macular pucker, macular hole, age-related macular degeneration, vitreomacular traction, proliferative vitreoretinopathy, proliferative diabetic retinopathy, and inherited vitreoretinopathies. (1,2) The molecular composition of the vitreous substructures is not known. Since the vitreous body is transparent with limited surgical access, it has been difficult to study its substructures at the molecular level. We developed a method to separate and preserve these tissues for proteomic and biochemical analysis. The dissection technique in this experimental video shows how to isolate vitreous base, anterior hyaloid, vitreous core, and vitreous cortex from postmortem human eyes. One-dimensional SDS-PAGE analyses of each vitreous component showed that our dissection technique resulted in four unique protein profiles corresponding to each substructure of the human vitreous body. Identification of differentially compartmentalized proteins will reveal candidate molecules underlying various vitreoretinal diseases.

  17. Revisiting global body politics in Nepal: A reflexive analysis.

    Science.gov (United States)

    Harcourt, Wendy

    2016-01-01

    Using the example of a human rights training in Nepal, the author looks at global body politics in a reflexive piece on her engagement in development practices that translate western feminist ideas on gender inequality and empowerment via UN human rights policies into non-western contexts. It firsts look at postcolonial and critical literature on feminist engagement in gender and development processes including a discussion on the concept of global body politics before examining briefly the framing of gender-based violence in Nepal. The core of the paper is a reflexive analysis and interrogation of the training in Nepal in order to bring out the tensions and contradictions around western developmental, feminist and human rights discourses. The discussion looks at how difficult it is for feminist, human rights and developmental discourses and practices to unmoor themselves from the notion of the 'expert' and those who do the rights/work/righting rights training and those who are perennially seen as requiring training. The conclusion reflects on possibilities of other epistemic practices found in intercultural dialogues.

  18. Monitoring activities of daily living based on wearable wireless body sensor network.

    Science.gov (United States)

    Kańtoch, E; Augustyniak, P; Markiewicz, M; Prusak, D

    2014-01-01

    With recent advances in microprocessor chip technology, wireless communication, and biomedical engineering it is possible to develop miniaturized ubiquitous health monitoring devices that are capable of recording physiological and movement signals during daily life activities. The aim of the research is to implement and test the prototype of health monitoring system. The system consists of the body central unit with Bluetooth module and wearable sensors: the custom-designed ECG sensor, the temperature sensor, the skin humidity sensor and accelerometers placed on the human body or integrated with clothes and a network gateway to forward data to a remote medical server. The system includes custom-designed transmission protocol and remote web-based graphical user interface for remote real time data analysis. Experimental results for a group of humans who performed various activities (eg. working, running, etc.) showed maximum 5% absolute error compared to certified medical devices. The results are promising and indicate that developed wireless wearable monitoring system faces challenges of multi-sensor human health monitoring during performing daily activities and opens new opportunities in developing novel healthcare services.

  19. Analysis Of Dynamic Dent Resistance Of Auto Body Panel

    Science.gov (United States)

    Deolgaonkar, S. S.; Nandedkar, V. M.

    2007-04-01

    In automotive industry there is increasing demand for higher quality exterior panels, better functional properties and lower weight. The demand for weight reduction has led to thinner sheets, greater use of high strength steels and a change from steel to aluminum grades. This thickness reduction, which causes decrease in the dent resistance, promoted examination of the dent resistance against static and dynamic concentrated loads. This paper describes an investigation of the suitability of explicit dynamic FE analysis as a mean to determine the dynamic dent properties of the panel. This investigation is carried out on the body panel of utility vehicle and covers two parts, in first experimental analysis is carried out on developed test rig, which is interfaced with the computer. This test rig measures deflection with accuracy of .001mm. The experimental results are then compared with the simulation results, which is the second part. Simulation is carried with non-linear transient dynamic explicit analysis using Ansys -Ls Dyna. The experimental results show great accuracy with simulation results. The effect of change in thickness and geometry of the existing fender is then studied with help of simulation technique. By considering the best possible option overall weight of fender is reduced by 7.07 % by keeping the dent resistance of the panel constant.

  20. Inadequacy of Body Weight-Based Recommendations for Individual Protein Intake—Lessons from Body Composition Analysis

    OpenAIRE

    Corinna Geisler; Prado, Carla M.; Müller, Manfred J.

    2016-01-01

    Current body weight-based protein recommendations are ignoring the large variability in body composition, particularly lean mass (LM), which drives protein requirements. We explored and highlighted the inter-individual variability of weight versus body composition-adjusted protein intakes by secondary analysis in three cohorts of (1) 574 healthy adults (mean ± SD age: 41.4 ± 15.2 years); (2) 403 cirrhotic patients (age: 44.7 ± 12.3 years) and (3) 547 patients with lung cancer (age: 61.3 ± 8.2...

  1. Activate Your Body (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2016-09-15

    As people age, it gets tougher to be physically active. While cutting back on certain activities is inevitable, finding ways to exercise on a regular basis is important for maintaining good health. In this podcast, Dr. Kathy Watson discusses the importance of older adults maintaining an active lifestyle.  Created: 9/15/2016 by MMWR.   Date Released: 9/15/2016.

  2. 200 terms for 'embodied activity'. The body in interaction: terminology for the body in ROLSI papers

    DEFF Research Database (Denmark)

    Nevile, Maurice Richard

    2016-01-01

    In this guest blog, Maurice Nevile tracks the way that articles in ROLSI have coped with the complex task of choosing what terms to use in describing …. well, what to call it? Bodily movement? Embodied activity? Gesture? Each of these (and many more) have pros and cons as descriptors. But with th...

  3. Recognizing Multi-user Activities using Body Sensor Networks

    DEFF Research Database (Denmark)

    Gu, Tao; Wang, Liang; Chen, Hanhua

    2011-01-01

    The advances of wireless networking and sensor technology open up an interesting opportunity to infer human activities in a smart home environment. Existing work in this paradigm focuses mainly on recognizing activities of a single user. In this work, we address the fundamental problem of recogni...

  4. Tyrosinase activity and isoform composition in separate tissues during development of Agaricus bisporus fruit bodies

    NARCIS (Netherlands)

    Leeuwen, van J.; Wichers, H.J.

    1999-01-01

    During growth of Agaricus bisporus fruit bodies the amount of active tyrosinase increased. The amount of active tyrosinase can be related to the degree of browning, as opposed to the fully activated tyrosinase level. Isoelectric focusing revealed that active and latent tyrosinase isoforms having dif

  5. Active Ageing: An Analysis

    Directory of Open Access Journals (Sweden)

    Alina-Cristina Nuta

    2011-10-01

    Full Text Available The problem of ageing is a highly topical for Romania and for European Union. In this framework, to create and implement some strategies for active ageing is an important objective. The international and regional forums set (supported by official statistics that the number of older people growing rapidly. Romania needs some programmes (with labour, social, economic, health care aspects to deal with the demographic changes, programs that will reform the existing working life structures and legislation. Despite the actual pension reform, which tries to close the opportunity of early retirement (by penalizing the total pension flows, or increasing the retirement age, etc., the labour system does not sets some important targets for this area.

  6. Body mass index in Parkinson's disease: a meta-analysis.

    Science.gov (United States)

    van der Marck, Marjolein A; Dicke, Heleen C; Uc, Ergun Y; Kentin, Zippora H A; Borm, George F; Bloem, Bastiaan R; Overeem, Sebastiaan; Munneke, Marten

    2012-03-01

    Prior work suggested that patients with Parkinson's disease (PD) have a lower Body Mass Index (BMI) than controls, but evidence is inconclusive. We therefore conducted a meta-analysis on BMI in PD. We searched MEDLINE, EMBASE, Cinahl and Scopus to identify cohort studies on BMI in PD, published before February 2011. Studies that reported mean BMI for PD patients and healthy controls were eligible. Twelve studies were included, with a total of 871 patients and 736 controls (in three studies controls consisted of subjects from other published studies). Our primary aim was to assess differences in BMI between patients and controls; this was analyzed with random effects meta-analysis. Our secondary aim was to evaluate the relation with disease severity (Hoehn and Yahr stage) and disease duration, using random effects meta-regression. PD patients had a significantly lower BMI than controls (overall effect 1.73, 95% CI 1.11-2.35, Pnutritional status should be part of PD management.

  7. A refractometry-based glucose analysis of body fluids.

    Science.gov (United States)

    Zirk, Kai; Poetzschke, Harald

    2007-05-01

    In principle, refractometry appears to be a suitable method for the measurement of glucose concentrations in body fluids (such as blood and the intercellular fluid), even though the refractive index of the measured samples, as an additive property, is not specific. But, if certain conditions are fulfilled, the glucose content can be calculated using the refractive index in combination with values from a further measurement. This study describes the determination of the glucose content using refractometry in human blood serum derivates, which were selected - due to their ready availability - to be used as a model for interstitial fluid. Refractometry of body fluids requires the elimination of disturbing components from the measurement sample. First of all, a homogenous fluid (i.e. consisting of one phase) is required, so that all cells and components in suspension need to be separated out. Furthermore, certain dissolved macromolecular components which are known to disturb the measurement process must also be removed. In human serum samples which had been ultrafiltrated with a range of ultrafilters of different pore sizes, a comparative evaluation showed that only ultrafiltration through a filter with a separation limit of between 3 and 30kDa resulted in maximal reduction of the refractive index (compared to native serum), whereas ultrafilters with greater separation limits did not. The total content of osmotically active solutes (the tonicity) also exerts a clear influence. However, exemplary measurements in blood plasma fluid from one volunteer showed that the electrical conductivity is (without an additive component) directly proportional to the osmolality: physiological changes in the state of body hydration (hyperhydration and dehydration) do not lead to any considerable changes in the relation between ionised and uncharged solute particles, but instead result in a sufficiently clear dilution or concentration of the blood fluid's low molecular components. This

  8. Refolding techniques for recovering biologically active recombinant proteins from inclusion bodies.

    Science.gov (United States)

    Yamaguchi, Hiroshi; Miyazaki, Masaya

    2014-02-20

    Biologically active proteins are useful for studying the biological functions of genes and for the development of therapeutic drugs and biomaterials in a biotechnology industry. Overexpression of recombinant proteins in bacteria, such as Escherichia coli, often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. As inclusion bodies contain relatively pure and intact proteins, protein refolding is an important process to obtain active recombinant proteins from inclusion bodies. However, conventional refolding methods, such as dialysis and dilution, are time consuming and, often, recovered yields of active proteins are low, and a trial-and-error process is required to achieve success. Recently, several approaches have been reported to refold these aggregated proteins into an active form. The strategies largely aim at reducing protein aggregation during the refolding procedure. This review focuses on protein refolding techniques using chemical additives and laminar flow in microfluidic chips for the efficient recovery of active proteins from inclusion bodies.

  9. The articulated body. Physical activity, fitness and neew technologies of health

    DEFF Research Database (Denmark)

    Otto, Lene

    2010-01-01

    of anticipations of fit bodies as essential to individual health. I identify a physical activity discourse in which new modes of knowing, experiencing and doing bodies involve new types of health technologies in which bodies must be connected to mechanical and electronic appliances, inscribed with biomedical...... discourses. The growing significance of obesity has meant that scientific measurements of physical activity and fitness are ubiquitous in the Western world. Health promotion campaigns persuade the population to meet expectations of normality by encouraging participation in a certain number of minutes...... of physical exercise every day. These practices serve to maintain a particular way of understanding the body and how it can (or should) be enacted. Focusing on the role of physical activity and fitness in health promotion, I explore how physical exercise as a social-material technology, through which the body...

  10. Turtles (Chelodina longicollis) regulate muscle metabolic enzyme activity in response to seasonal variation in body temperature.

    Science.gov (United States)

    Seebacher, F; Sparrow, J; Thompson, M B

    2004-04-01

    Fluctuations in the thermal environment may elicit different responses in animals: migration to climatically different areas, regulation of body temperature, modification of biochemical reaction rates, or assuming a state of dormancy. Many ectothermic reptiles are active over a range of body temperatures that vary seasonally. Here we test the hypothesis that metabolic enzyme activity acclimatises seasonally in freshwater turtles (Chelodina longicollis) in addition to, or instead of, behavioural regulation of body temperatures. We measured body temperatures in free-ranging turtles (n = 3) by radiotelemetry, and we assayed phosphofructokinase (PFK), lactate dehydrogenase (LDH), citrate synthase (CS) and cytochrome c oxidase (CCO) activities in early autumn (March, n = 10 turtles), late autumn (May, n = 7) and mid-winter (July, n = 7) over a range of assay temperatures (10 degrees C, 15 degrees C, 20 degrees C, 25 degrees C). Body temperatures were either not different from, or higher than expected from a theoretical null-distribution of a randomly moving animal. Field body temperatures at any season were lower, however, than expected from animals that maximised their sun exposure. Turtles maintained constant PFK, LDH and CCO activities in different months, despite body temperature differences of nearly 13.0 degrees C between March (average daily body temperature = 24.4 degrees C) and July (average = 11.4 degrees C). CS activity did not vary between March and May (average daily body temperature = 20.2 degrees C), but it decreased in July. Thus C. longicollis use a combination of behavioural thermoregulation and biochemical acclimatisation in response to seasonally changing thermal conditions. Ectothermic reptiles were often thought not to acclimatise biochemically, and our results show that behavioural attainment of a preferred body temperature is not mandatory for activity or physiological performance in turtles.

  11. Influence of body temperature on the evoked activity in mouse visual cortex.

    Science.gov (United States)

    Tang, Bin; Kalatsky, Valery A

    2013-06-01

    Optical imaging of intrinsic signals and conventional electrophysiological methods were used to investigate the correlation between the evoked activity in mouse visual cortex and core body temperature. The results show that hypothermia (25-36 °C) decreases the intensity of optical imaging in the visual cortex and the imaging signal reversibly disappears at 25 °C. Hyperthermia (39-41 °C) increases the intensity but decreases the quality of cortical imaging when body temperature is above 40 °C. The change of optical imaging was in line with that of neuronal activities and local field potentials (LFPs) directly recorded from the visual cortex at 25-39 °C. Hypothermia decreases neuron firing rate and LFPs amplitude. Most of the recorded neurons ceased firing to visual stimulation at 25 °C. Hyperthermia increases neuronal firing rate and LFPs amplitude. Both are reduced when body temperature is above 40 °C, though neither change was statistically significant. These results suggest: (1) Body temperature has an important impact on the visual cortical evoked activities and optical imaging generally reflects these effects when body temperature is between 25 and 39 °C; (2) Optical imaging may not properly reflect the neuronal activity when body temperature is over 40 °C. It is important to maintain core body temperature within 3 °C of the normal body temperature to obtain verifiable results.

  12. Interplay between body stabilisation and quadriceps muscle activation capacity.

    Science.gov (United States)

    Bampouras, Theodoros M; Reeves, Neil D; Baltzopoulos, Vasilios; Maganaris, Constantinos N

    2017-03-22

    The study aimed to distinguish the effect of stabilisation and muscle activation on quadriceps maximal isometric voluntary contraction (MVC) torque generation. Nine subjects performed (a) an MVC with restrained leg and pelvis (Typical MVC), (b) a Typical MVC with handgrip (Handgrip MVC), (c) an MVC focusing on contracting the knee extensors only (Isolated knee extension MVC), and (d) an MVC with unrestrained leg and pelvis (Unrestrained MVC). Torque and activation capacity between conditions were compared with repeated measures ANOVA and dependent t-tests. EMG (from eleven remote muscles) was compared using Friedman's and Wilcoxon. Typical MVC (277.2±49.6Nm) and Handgrip MVC (261.0±55.4Nm) were higher than Isolated knee extension MVC (210.2±48.3Nm, pMVC (195.2±49.7Nm, pMVC (83.1±15.9%) activation was higher than Isolated knee extension MVC (68.9±24.3%, pMVC and Handgrip MVC (81.8±17.4%) were higher than Unrestrained MVC (64.9±16.2%, pMVC consistently lower than Typical MVC or Handgrip MVC. Stabilisation of the involved segments is the prime concern allowing fuller activation of the muscle, reinforcing the need for close attention to stabilisation during dynamometry-based knee joint functional assessment.

  13. Physical Activity Plays an Important Role in Body Weight Regulation

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Chaput

    2011-01-01

    Full Text Available Emerging literature highlights the need to incorporate physical activity into every strategy intended to prevent weight gain as well as to maintain weight loss over time. Furthermore, physical activity should be part of any plan to lose weight. The stimulus of exercise provides valuable metabolic adaptations that improve energy and macronutrient balance regulation. A tight coupling between energy intake and energy expenditure has been documented at high levels of physical exercise, suggesting that exercise may improve appetite control. The regular practice of physical activity has also been reported to reduce the risk of stress-induced weight gain. A more personalized approach is recommended when planning exercise programs in a clinical weight loss setting in order to limit the compensatory changes associated to exercise-induced weight loss. With modern environment promoting overeating and sedentary behavior, there is an urgent need for a concerted action including legislative measures to promote healthy active living in order to curb the current epidemic of chronic diseases.

  14. Analysis of an idealized body-vortex systems

    DEFF Research Database (Denmark)

    Pedersen, Johan Rønby; Aref, Hassan

    2008-01-01

    We explore the class of dynamical systems consisting of a body, N point vortices, and one or more passive particles in an ideal, unbounded, planar fluid. The body is represented by a closed curve and is free to move in response to the fluid motion. The vortices have fixed strengths and are intended...... in hand. They can be analyzed using techniques from the theory of dynamical systems with a finite number of degrees of freedom. The simplest such system, a single point vortex and a circular body, is integrable. If we add vortices, or change other features of the system such as the body shape, the motion...

  15. Daily physical activity related to aerobic fitness and body fat in an urban sample of children

    DEFF Research Database (Denmark)

    Dencker, M; Thorsson, O; Karlsson, M K;

    2008-01-01

    -energy x-ray absorptiometry. TBF was calculated as percentage of total body mass (BF%). Body fat distribution was calculated as AFM/TBF. Aerobic fitness was measured by indirect calorimetry during a maximal cycle ergometer exercise test. Daily physical activity was assessed by accelerometers for 4 days......This study evaluates associations between objectively measured daily physical activity vs aerobic fitness and body fat in children aged 8-11 years. A cross-sectional study of 225 children aged 7.9-11.1 years was performed. Abdominal fat mass (AFM) and total body fat (TBF) were quantified by dual...... and daily accumulation of moderate-to-vigorous and vigorous activity was calculated. Significant relationships (Pfitness (r=0.38), whereas moderate-to-vigorous activity displayed weaker relationships...

  16. Lung volumes related to physical activity, physical fitness, aerobic capacity and body mass index in students

    Directory of Open Access Journals (Sweden)

    Mihailova A.

    2016-01-01

    Reduced lung volumes were associated with lower aerobic fitness, lower physical fitness and lower amount of weekly physical activity. Healthier body mass index was associated with higher aerobic fitness (relative VO2max in both female and male.

  17. Whole-Body MRI versus PET in assessment of multiple myeloma disease activity.

    LENUS (Irish Health Repository)

    Shortt, Conor P

    2009-04-01

    The purpose of this study was to compare FDG PET; whole-body MRI; and the reference standard, bone marrow aspiration and biopsy, to determine the best imaging technique for assessment of disease activity in multiple myeloma.

  18. A Comparing of Body Composition Components in Physically Active and Inactive Male Students of Sharoud University of Technology

    Directory of Open Access Journals (Sweden)

    Hassan Bahrololoum

    2010-01-01

    Full Text Available Introduction: Obesity is a serious health problem that reduces life expectancy by increasing one's risk of developing coronary artery disease, hypertension, type 2 diabetes, obstructive pulmonary disease, osteoarthritis and certain types of cancer. Moreover, body composition is divided into fat and fat free mass components. Research shows that physical activity is an important factor that affects body composition. This research aimed at estimating and comparing the body composition components of physically active and inactive male student of Shahroud University of technologyMethods: Participants of this study were 70 inactive male students with average age of (20.86±1.72 years and 65 physically active male students with average age of (20.86±1.72 years. The participants were randomly selected through stratified sampling procedure from various faculties and different admission years. Body composition was estimated with Body composition analyzer system that measured body composition components using bioelectrical impedance method.Results: Data analysis with SPSS-15 software revealed that: average of BF% in physically active sample was (13.43±3.15 and average of inactive samples was (16.73±6.16 which statistically showed significant difference (P<0.001 ; the LBM in physically active samples was (60.27±8.05 Kg and average of inactive samples was (56.43±7.6 Kg which statistically showed significant difference (P<0.005; the average of BMI in physically active sample was (22.62±2.8 kgm and average of inactive samples was (22.25±3.84 kgm which statistically did not show significant difference (P=0.519; the WHR average of physically active samples was (0.798±.03m and average of inactive samples was (0.81±.06m and there was not a significant difference between the two groups. Conclusion: These results revealed that body composition of physically active students were better than that of the inactive ones, so it can be concluded that there is a

  19. Methyl jasmonate affects morphology, number and activity of endoplasmic reticulum bodies in Raphanus sativus root cells.

    Science.gov (United States)

    Gotté, Maxime; Ghosh, Rajgourab; Bernard, Sophie; Nguema-Ona, Eric; Vicré-Gibouin, Maïté; Hara-Nishimura, Ikuko; Driouich, Azeddine

    2015-01-01

    The endoplasmic reticulum (ER) bodies are ER-derived structures that are found in Brassicaceae species and thought to play a role in defense. Here, we have investigated the occurrence, distribution and function of ER bodies in root cells of Raphanus sativus using a combination of microscopic and biochemical methods. We have also assessed the response of ER bodies to methyl jasmonate (MeJA), a phytohormone that mediates plant defense against wounding and pathogens. Our results show that (i) ER bodies do occur in different root cell types from the root cap region to the differentiation zone; (ii) they do accumulate a PYK10-like protein similar to the major marker protein of ER bodies that is involved in defense in Arabidopsis thaliana; and (iii) treatment of root cells with MeJA causes a significant increase in the number of ER bodies and the activity of β-glucosidases. More importantly, MeJA was found to induce the formation of very long ER bodies that results from the fusion of small ones, a phenomenon that has not been reported in any other study so far. These findings demonstrate that MeJA impacts the number and morphology of functional ER bodies and stimulates ER body enzyme activities, probably to participate in defense responses of radish root. They also suggest that these structures may provide a defensive system specific to root cells.

  20. Age, Physical Activity, Physical Fitness, Body Composition, and Incidence of Orthopedic Problems.

    Science.gov (United States)

    Research Quarterly for Exercise and Sport, 1989

    1989-01-01

    Effects of age, physical activity, physical fitness, and body mass index (BMI) on the occurrence of orthopedic problems were examined. For men, physical fitness, BMI, and physical activity were associated with orthopedic problems; for women, physical activity was the main predictor. Age was not a factor for either gender. (JD)

  1. Maternal Physical Activity and Insulin Action in Pregnancy and Their Relationships With Infant Body Composition

    OpenAIRE

    Pomeroy, Jeremy; Renström, Frida; Gradmark, Anna M.; Mogren, Ingrid; Persson, Margareta; Bluck, Les; Wright, Antony; Kahn, Steven E; Domellöf, Magnus; Franks, Paul W.

    2013-01-01

    OBJECTIVE We sought to assess the association between maternal gestational physical activity and insulin action and body composition in early infancy. RESEARCH DESIGN AND METHODS At 28–32 weeks' gestation, pregnant women participating in an observational study in Sweden underwent assessments of height, weight, and body composition, an oral glucose tolerance test, and 10 days of objective physical activity assessment. Thirty mothers and infants returned at 11–19 weeks postpartum. Infants under...

  2. Factors associated with body image dissatisfaction in Portuguese adolescents: obesity, sports activity and TV watching

    Directory of Open Access Journals (Sweden)

    Eduarda Maria Rocha Teles de Castro Coelho

    2016-10-01

    Full Text Available This cross-sectional study intended to determine the prevalence of body image dissatisfaction and associated factors in Portuguese adolescents (N=529, 10-18 years, 53.7% male and 46.3% female. The prevalence of body dissatisfaction (estimated through Collins's silhouettes was 58%. Multivariate logistic regression analyses showed that the variables associated were: obesity, watch TV over 2 hours/day and practice sport activities 4 or more days/week. In male, obesity and watch TV over 2 hours/day were related to body dissatisfaction and among female only obesity had statistical significance. It is necessary to considered different public health interventions for men and women in order to reduce this high body image dissatisfaction.   Keywords: Body image, adolescence, gender, obesity, sports activity

  3. MBD3 localizes at promoters, gene bodies and enhancers of active genes.

    Science.gov (United States)

    Shimbo, Takashi; Du, Ying; Grimm, Sara A; Dhasarathy, Archana; Mav, Deepak; Shah, Ruchir R; Shi, Huidong; Wade, Paul A

    2013-01-01

    The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin structure by nucleosome remodeling and histone deacetylation activities. Recent reports describing localization of NuRD provide new insights that question previous models on NuRD action, but are not in complete agreement. Here, we provide location analysis of endogenous MBD3, a component of NuRD complex, in two human breast cancer cell lines (MCF-7 and MDA-MB-231) using two independent genomic techniques: DNA adenine methyltransferase identification (DamID) and ChIP-seq. We observed concordance of the resulting genomic localization, suggesting that these studies are converging on a robust map for NuRD in the cancer cell genome. MBD3 preferentially associated with CpG rich promoters marked by H3K4me3 and showed cell-type specific localization across gene bodies, peaking around the transcription start site. A subset of sites bound by MBD3 was enriched in H3K27ac and was in physical proximity to promoters in three-dimensional space, suggesting function as enhancers. MBD3 enrichment was also noted at promoters modified by H3K27me3. Functional analysis of chromatin indicated that MBD3 regulates nucleosome occupancy near promoters and in gene bodies. These data suggest that MBD3, and by extension the NuRD complex, may have multiple roles in fine tuning expression for both active and silent genes, representing an important step in defining regulatory mechanisms by which NuRD complex controls chromatin structure and modification status.

  4. Activity of processes on the visible surfaces of Solar System bodies

    Science.gov (United States)

    Vidmachenko, A. P.

    2016-10-01

    We consider the physical processes on the surfaces of Solar System bodies, which lead to visible changes in their reflective characteristics. It is shown that each body in the Solar system has a set of chemical elements and their compounds, converting of which indicates significant activity in such a significant temperature change range from 700 K (for Mercury) to 30 K for Pluto. That is, all objects in the Solar system show a significant activity. However, they are very individual for the list and the type of the processes that take place on each body in the Solar system.

  5. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    DEFF Research Database (Denmark)

    Felix, Janine F; Bradfield, Jonathan P; Monnereau, Claire;

    2016-01-01

    A large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown. We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores. We...

  6. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    NARCIS (Netherlands)

    J.F. Felix (Janine); J.P. Bradfield (Jonathan); C. Monnereau; R.J.P. van der Valk (Ralf); E. Stergiakouli (Evie); A. Chesi (Alessandra); R. Gaillard (Romy); B. Feenstra (Bjarke); E. Thiering (Elisabeth); E. Kreiner-Møller (Eskil); A. Mahajan (Anubha); Niina Pitkänen; R. Joro (Raimo); A. Cavadino (Alana); V. Huikari (Ville); S. Franks (Steve); M. Groen-Blokhuis (Maria); D.L. Cousminer (Diana); J.A. Marsh (Julie); T. Lehtimäki (Terho); J.A. Curtin (John); J. Vioque (Jesus); T.S. Ahluwalia (Tarunveer Singh); R. Myhre (Ronny); T.S. Price (Thomas); Natalia Vilor-Tejedor; L. Yengo (Loic); N. Grarup (Niels); I. Ntalla (Ioanna); W.Q. Ang (Wei); M. Atalay (Mustafa); H. Bisgaard (Hans); A.I.F. Blakemore (Alexandra); A. Bonnefond (Amélie); L. Carstensen (Lisbeth); J.G. Eriksson (Johan G.); C. Flexeder (Claudia); L. Franke (Lude); F. Geller (Frank); M. Geserick (Mandy); A.L. Hartikainen; C.M.A. Haworth (Claire M.); J.N. Hirschhorn (Joel N.); A. Hofman (Albert); J.-C. Holm (Jens-Christian); M. Horikoshi (Momoko); J.J. Hottenga (Jouke Jan); J. Huang (Jian); H.N. Kadarmideen (Haja N.); M. Kähönen (Mika); W. Kiess (Wieland); T.A. Lakka (Timo); T.A. Lakka (Timo); A. Lewin (Alex); L. Liang (Liming); L.-P. Lyytikäinen (Leo-Pekka); B. Ma (Baoshan); P. Magnus (Per); S.E. McCormack (Shana E.); G. Mcmahon (George); F.D. Mentch (Frank); C.M. Middeldorp (Christel); C.S. Murray (Clare S.); K. Pahkala (Katja); T.H. Pers (Tune); R. Pfäffle (Roland); D.S. Postma (Dirkje); C. Power (Christine); A. Simpson (Angela); V. Sengpiel (Verena); C. Tiesler (Carla); M. Torrent (Maties); A.G. Uitterlinden (André); J.B.J. van Meurs (Joyce); R. Vinding (Rebecca); J. Waage (Johannes); J. Wardle (Jane); E. Zeggini (Eleftheria); B.S. Zemel (Babette S.); G.V. Dedoussis (George); O. Pedersen (Oluf); P. Froguel (Philippe); J. Sunyer (Jordi); R. Plomin (Robert); B. Jacobsson (Bo); T. Hansen (Torben); J.R. Gonzalez (Juan R.); A. Custovic; O.T. Raitakari (Olli T.); C.E. Pennell (Craig); Elisabeth Widén; D.I. Boomsma (Dorret); G.H. Koppelman (Gerard); S. Sebert (Sylvain); M.-R. Jarvelin (Marjo-Riitta); E. Hypponen (Elina); M.I. McCarthy (Mark); V. Lindi (Virpi); N. Harri (Niinikoski); A. Körner (Antje); K. Bønnelykke (Klaus); J. Heinrich (Joachim); M. Melbye (Mads); F. Rivadeneira Ramirez (Fernando); H. Hakonarson (Hakon); S.M. Ring (Susan); G.D. Smith; T.I.A. Sørensen (Thorkild I.A.); N. Timpson (Nicholas); S.F. Grant; V.W.V. Jaddoe (Vincent W. V.); H.J. Kalkwarf (Heidi J.); J.M. Lappe (Joan M.); V. Gilsanz (Vicente); S.E. Oberfield (Sharon E.); J.A. Shepherd (John A.); A. Kelly (Andrea)

    2016-01-01

    textabstractA large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown.We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation sc

  7. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

    NARCIS (Netherlands)

    Felix, Janine F; Bradfield, Jonathan P; Monnereau, Claire; van der Valk, Ralf J P; Stergiakouli, Evie; Chesi, Alessandra; Gaillard, Romy; Feenstra, Bjarke; Thiering, Elisabeth; Kreiner-Møller, Eskil; Mahajan, Anubha; Pitkänen, Niina; Joro, Raimo; Cavadino, Alana; Huikari, Ville; Franks, Steve; Groen-Blokhuis, Maria M; Cousminer, Diana L; Marsh, Julie A; Lehtimäki, Terho; Curtin, John A; Vioque, Jesus; Ahluwalia, Tarunveer S; Myhre, Ronny; Price, Thomas S; Vilor-Tejedor, Natalia; Yengo, Loïc; Grarup, Niels; Ntalla, Ioanna; Ang, Wei; Atalay, Mustafa; Bisgaard, Hans; Blakemore, Alexandra I; Bonnefond, Amelie; Carstensen, Lisbeth; Eriksson, Johan; Flexeder, Claudia; Franke, Lude; Geller, Frank; Geserick, Mandy; Hartikainen, Anna-Liisa; Haworth, Claire M A; Hirschhorn, Joel N; Hofman, Albert; Holm, Jens-Christian; Horikoshi, Momoko; Hottenga, Jouke Jan; Huang, Jinyan; Kadarmideen, Haja N; Kähönen, Mika; Kiess, Wieland; Lakka, Hanna-Maaria; Lakka, Timo A; Lewin, Alexandra M; Liang, Liming; Lyytikäinen, Leo-Pekka; Ma, Baoshan; Magnus, Per; McCormack, Shana E; McMahon, George; Mentch, Frank D; Middeldorp, Christel M; Murray, Clare S; Pahkala, Katja; Pers, Tune H; Pfäffle, Roland; Postma, Dirkje S; Power, Christine; Simpson, Angela; Sengpiel, Verena; Tiesler, Carla M T; Torrent, Maties; Uitterlinden, André G; van Meurs, Joyce B; Vinding, Rebecca; Waage, Johannes; Wardle, Jane; Zeggini, Eleftheria; Zemel, Babette S; Dedoussis, George V; Pedersen, Oluf; Froguel, Philippe; Sunyer, Jordi; Plomin, Robert; Jacobsson, Bo; Hansen, Torben; Gonzalez, Juan R; Custovic, Adnan; Raitakari, Olli T; Pennell, Craig E; Widén, Elisabeth; Boomsma, Dorret I; Koppelman, Gerard H; Sebert, Sylvain; Järvelin, Marjo-Riitta; Hyppönen, Elina; McCarthy, Mark I; Lindi, Virpi; Harri, Niinikoski; Körner, Antje; Bønnelykke, Klaus; Heinrich, Joachim; Melbye, Mads; Rivadeneira, Fernando; Hakonarson, Hakon; Ring, Susan M; Smith, George Davey; Sørensen, Thorkild I A; Timpson, Nicholas J; Grant, Struan F A; Jaddoe, Vincent W V

    2015-01-01

    A large number of genetic loci are associated with adult body mass index. However, the genetics of childhood body mass index are largely unknown. We performed a meta-analysis of genome-wide association studies of childhood body mass index, using sex- and age-adjusted standard deviation scores. We in

  8. Fitness, daily activity and body composition in children with newly diagnosed, untreated asthma

    DEFF Research Database (Denmark)

    Vahlkvist, S; Pedersen, S

    2009-01-01

    Background: Information about how the asthma disease affects the life style and health in children is sparse. Aim: To measure fitness, daily physical activity and body composition in children with newly diagnosed, untreated asthma and healthy controls, and to assess the association between...... the level of asthma control and these parameters. Methods: Daily physical activity measured using accelerometry, cardiovascular fitness and body composition (per cent fat, per cent lean tissue and bone mineral density) were measured in 57 children with newly diagnosed, untreated asthma and in 157 healthy...... fitness and daytime spent in intensive activity. Overweight children are physically less active than normal weight children....

  9. Sepsis-induced morbidity in mice: effects on body temperature, body weight, cage activity, social behavior and cytokines in brain.

    Science.gov (United States)

    Granger, Jill I; Ratti, Pietro-Luca; Datta, Subhash C; Raymond, Richard M; Opp, Mark R

    2013-07-01

    Infection negatively impacts mental health, as evidenced by the lethargy, malaise, and cognitive deficits experienced during illness. These changes in central nervous system processes, collectively termed sickness behavior, have been shown in animal models to be mediated primarily by the actions of cytokines in brain. Most studies of sickness behavior to date have used bolus injection of bacterial lipopolysaccharide (LPS) or selective administration of the proinflammatory cytokines interleukin-1β (IL-1β) or IL-6 as the immune challenge. Such models, although useful for determining mechanisms responsible for acute changes in physiology and behavior, do not adequately represent the more complex effects on central nervous system (CNS) processes of a true infection with replicating pathogens. In the present study, we used the cecal ligation and puncture (CLP) model to quantify sepsis-induced alterations in several facets of physiology and behavior of mice. We determined the impact of sepsis on cage activity, body temperature, food and water consumption and body weights of mice. Because cytokines are critical mediators of changes in behavior and temperature regulation during immune challenge, we also quantified sepsis-induced alterations in cytokine mRNA and protein in brain during the acute period of sepsis onset. We now report that cage activity and temperature regulation in mice that survive are altered for up to 23 days after sepsis induction. Food and water consumption are transiently reduced, and body weight is lost during sepsis. Furthermore, sepsis decreases social interactions for 24-48 h. Finally, mRNA and protein for IL-1β, IL-6, and tumor necrosis factor-α (TNFα) are upregulated in the hypothalamus, hippocampus, and brain stem during sepsis onset, from 6h to 72 h post sepsis induction. Collectively, these data indicate that sepsis not only acutely alters physiology, behavior and cytokine profiles in brain, but that some brain functions are impaired for

  10. Body-related self-conscious emotions relate to physical activity motivation and behavior in men.

    Science.gov (United States)

    Castonguay, Andree L; Pila, Eva; Wrosch, Carsten; Sabiston, Catherine M

    2015-05-01

    The aim of this study was to examine the associations between the body-related self-conscious emotions of shame, guilt, and pride and physical activity motivation and behavior among adult males. Specifically, motivation regulations (external, introjected, indentified, intrinsic) were examined as possible mediators between each of the body-related self-conscious emotions and physical activity behavior. A cross-sectional study was conducted with adult men (N = 152; Mage = 23.72, SD = 10.92 years). Participants completed a questionnaire assessing body-related shame, guilt, authentic pride, hubristic pride, motivational regulations, and leisure-time physical activity. In separate multiple mediation models, body-related shame was positively associated with external and introjected regulations and negatively correlated with intrinsic regulation. Guilt was positively linked to external, introjected, and identified regulations. Authentic pride was negatively related to external regulation and positively correlated with both identified and intrinsic regulations and directly associated with physical activity behavior. Hubristic pride was positively associated with intrinsic regulation. Overall, there were both direct and indirect effects via motivation regulations between body-related self-conscious emotions and physical activity (R(2) shame = .15, guilt = .16, authentic pride = .18, hubristic pride = .16). These findings highlight the importance of targeting and understanding self-conscious emotions contextualized to the body and links to motivation and positive health behavior among men.

  11. Spacecraft motion analysis about rapid rotating small body

    Institute of Scientific and Technical Information of China (English)

    史雪岩; 崔祜涛; 崔平远; 栾恩杰

    2003-01-01

    The orbital dynamics equation of a spacecraft around an irregular sphere small body is established based on the small body' s gravitational potential approximated with a tri-axial ellipsoid. According to the Jacobi integral constant, the spacecraft zero-velocity curves in the vicinity of the small body is described and feasible motion region is analyzed. The limited condition and the periapsis radius corresponding to different eccentricity against impact surface are presented. The stability of direct and retrograde equator orbits is analyzed based on the perturbation solutions of mean orbit elements.

  12. sEMG during Whole-Body Vibration Contains Motion Artifacts and Reflex Activity

    Directory of Open Access Journals (Sweden)

    Karin Lienhard

    2015-01-01

    Full Text Available The purpose of this study was to determine whether the excessive spikes observed in the surface electromyography (sEMG spectrum recorded during whole-body vibration (WBV exercises contain motion artifacts and/or reflex activity. The occurrence of motion artifacts was tested by electrical recordings of the patella. The involvement of reflex activity was investigated by analyzing the magnitude of the isolated spikes during changes in voluntary background muscle activity. Eighteen physically active volunteers performed static squats while the sEMG was measured of five lower limb muscles during vertical WBV using no load and an additional load of 33 kg. In order to record motion artifacts during WBV, a pair of electrodes was positioned on the patella with several layers of tape between skin and electrodes. Spectral analysis of the patella signal revealed recordings of motion artifacts as high peaks at the vibration frequency (fundamental and marginal peaks at the multiple harmonics were observed. For the sEMG recordings, the root mean square of the spikes increased with increasing additional loads (p < 0.05, and was significantly correlated to the sEMG signal without the spikes of the respective muscle (r range: 0.54 - 0.92, p < 0.05. This finding indicates that reflex activity might be contained in the isolated spikes, as identical behavior has been found for stretch reflex responses evoked during direct vibration. In conclusion, the spikes visible in the sEMG spectrum during WBV exercises contain motion artifacts and possibly reflex activity.

  13. Analysis of Precision of Activation Analysis Method

    DEFF Research Database (Denmark)

    Heydorn, Kaj; Nørgaard, K.

    1973-01-01

    The precision of an activation-analysis method prescribes the estimation of the precision of a single analytical result. The adequacy of these estimates to account for the observed variation between duplicate results from the analysis of different samples and materials, is tested by the statistic T......, which is shown to be approximated by a χ2 distribution. Application of this test to the results of determinations of manganese in human serum by a method of established precision, led to the detection of airborne pollution of the serum during the sampling process. The subsequent improvement in sampling...... conditions was shown to give not only increased precision, but also improved accuracy of the results....

  14. Inadequacy of Body Weight-Based Recommendations for Individual Protein Intake-Lessons from Body Composition Analysis.

    Science.gov (United States)

    Geisler, Corinna; Prado, Carla M; Müller, Manfred J

    2016-12-31

    Current body weight-based protein recommendations are ignoring the large variability in body composition, particularly lean mass (LM), which drives protein requirements. We explored and highlighted the inter-individual variability of weight versus body composition-adjusted protein intakes by secondary analysis in three cohorts of (1) 574 healthy adults (mean ± SD age: 41.4 ± 15.2 years); (2) 403 cirrhotic patients (age: 44.7 ± 12.3 years) and (3) 547 patients with lung cancer (age: 61.3 ± 8.2 years). LM was assessed using different devices (magnetic resonance imaging, dual-energy X-ray absorptiometry, computer tomography, total body potassium and bioelectrical impedance), body weight-based protein intake, its ratio (per kg LM) and mean protein requirement were calculated. Variability in protein intake in all cohorts ranged from 0.83 to 1.77 g protein per kg LM per day using (theoretical protein intake of 60 g protein per day). Calculated mean protein requirement was 1.63 g protein per kg LM per day; consequently, 95.3% of healthy subjects, 100% of cirrhotic and 97.4% of cancer patients would present with a low protein intake per kg LM. Weight-adjusted recommendations are inadequate to address the LM specific differences in protein needs of healthy subjects or clinical populations. Absolute protein intake seems to be more relevant compared to the relative proportion of protein, which in turn changes with different energy needs.

  15. Inadequacy of Body Weight-Based Recommendations for Individual Protein Intake—Lessons from Body Composition Analysis

    Directory of Open Access Journals (Sweden)

    Corinna Geisler

    2016-12-01

    Full Text Available Current body weight-based protein recommendations are ignoring the large variability in body composition, particularly lean mass (LM, which drives protein requirements. We explored and highlighted the inter-individual variability of weight versus body composition-adjusted protein intakes by secondary analysis in three cohorts of (1 574 healthy adults (mean ± SD age: 41.4 ± 15.2 years; (2 403 cirrhotic patients (age: 44.7 ± 12.3 years and (3 547 patients with lung cancer (age: 61.3 ± 8.2 years. LM was assessed using different devices (magnetic resonance imaging, dual-energy X-ray absorptiometry, computer tomography, total body potassium and bioelectrical impedance, body weight-based protein intake, its ratio (per kg LM and mean protein requirement were calculated. Variability in protein intake in all cohorts ranged from 0.83 to 1.77 g protein per kg LM per day using (theoretical protein intake of 60 g protein per day. Calculated mean protein requirement was 1.63 g protein per kg LM per day; consequently, 95.3% of healthy subjects, 100% of cirrhotic and 97.4% of cancer patients would present with a low protein intake per kg LM. Weight-adjusted recommendations are inadequate to address the LM specific differences in protein needs of healthy subjects or clinical populations. Absolute protein intake seems to be more relevant compared to the relative proportion of protein, which in turn changes with different energy needs.

  16. Inadequacy of Body Weight-Based Recommendations for Individual Protein Intake—Lessons from Body Composition Analysis

    Science.gov (United States)

    Geisler, Corinna; Prado, Carla M.; Müller, Manfred J.

    2016-01-01

    Current body weight-based protein recommendations are ignoring the large variability in body composition, particularly lean mass (LM), which drives protein requirements. We explored and highlighted the inter-individual variability of weight versus body composition-adjusted protein intakes by secondary analysis in three cohorts of (1) 574 healthy adults (mean ± SD age: 41.4 ± 15.2 years); (2) 403 cirrhotic patients (age: 44.7 ± 12.3 years) and (3) 547 patients with lung cancer (age: 61.3 ± 8.2 years). LM was assessed using different devices (magnetic resonance imaging, dual-energy X-ray absorptiometry, computer tomography, total body potassium and bioelectrical impedance), body weight-based protein intake, its ratio (per kg LM) and mean protein requirement were calculated. Variability in protein intake in all cohorts ranged from 0.83 to 1.77 g protein per kg LM per day using (theoretical protein intake of 60 g protein per day). Calculated mean protein requirement was 1.63 g protein per kg LM per day; consequently, 95.3% of healthy subjects, 100% of cirrhotic and 97.4% of cancer patients would present with a low protein intake per kg LM. Weight-adjusted recommendations are inadequate to address the LM specific differences in protein needs of healthy subjects or clinical populations. Absolute protein intake seems to be more relevant compared to the relative proportion of protein, which in turn changes with different energy needs. PMID:28042853

  17. "The moving body": a sustainable project to improve children's physical activity at kindergarten.

    Science.gov (United States)

    Serpentino, Carmela

    2011-10-01

    Physical activity promotes children's awareness of the body. Children, to experience and to learn, need to be physically active and their innate physical activity is playing. Playing together means building relationships with peers, means learning how to use tools and space, means addressing egocentric behaviour toward rules' respect; in summary, it means learning "social conviviality and respect". The aim of the project "The moving body" was to favour children's physical and cognitive development and their social relationships. Gross motor physical abilities were assessed in 270 children attending the kindergarten. The children were grouped according their level of motor abilities to promote learning through older children's imitation. Structured games and playing were alternated to free time, and words such as physical activity, movement, and so on, were never used. Every month the children were asked to draw their own body to assess their body shape perception and their ability in representing it. All the children improved their physical abilities as compared to the beginning of the project; they strengthened their creativity and fantasy, inventing new and imaginative games, became more confident in their own capacities, and they learned how to deal and overcome, with a greater autonomy, difficult tasks. The body shape perception, and its representation as drawing, showed, especially among children 3 years old, remarkable progress. The importance of physical activity and play in kindergarten activities was evidenced through the significant improvement of children's several specific motor and psychosocial competences.

  18. The role of body-related self-conscious emotions in motivating women's physical activity.

    Science.gov (United States)

    Sabiston, Catherine M; Brunet, Jennifer; Kowalski, Kent C; Wilson, Philip M; Mack, Diane E; Crocker, Peter R E

    2010-08-01

    The purpose of this study was to test a model where body-related self-conscious emotions of shame, guilt, and pride were associated with physical activity regulations and behavior. Adult women (N = 389; M age = 29.82, SD = 15.20 years) completed a questionnaire assessing body-related pride, shame, and guilt, motivational regulations, and leisure-time physical activity. The hypothesized measurement and structural models were deemed adequate, as was a revised model examining shame-free guilt and guilt-free shame. In the revised structural model, body-related pride was positively significantly related to identified and intrinsic regulations. Body-related shame-free guilt was significantly associated with external, introjected, and identified regulations. Body-related guilt-free shame was significantly positively related to external and introjected regulation, and negatively associated with intrinsic regulation. Identified and intrinsic regulations were significantly positively related to physical activity (R2 = .62). These findings highlight the importance of targeting and understanding the realm of body-related self-conscious emotions and the associated links to regulations and physical activity behavior.

  19. Values, body weight, and well being: the influence of the protestant ethic and consumerism on physical activity, eating, and body image.

    Science.gov (United States)

    Vanden Heede, Fred; Pelican, Suzanne; Holmes, Betty; Moore, Sylvia A; Buchanan, David

    This article explores how people's values shape their experiences and emotions with respect to physical activity, eating, and body image. It describes the results of a grounded theory analysis of individual and focus group interviews conducted as part of a community-based health improvement project, Wellness IN the Rockies (WIN the Rockies). The analysis links core theoretical constructs, including habitus, sedimentation, and natural attitude, to larger socio-cultural and historical trends embodied in the Protestant ethic and the rise of consumerism, illuminating how these values shape people's everyday understanding of their experiences. Key analytic frameworks focus on the socialization processes involved in inculcating values, identity formation, and moralization as they relate to health attitudes and behaviors. Major implications of the results are discussed, especially the need to enhance self-understanding about social values in health education.

  20. Body image satisfaction and the view of active old women about the influence of physical exercise in their self-image

    Directory of Open Access Journals (Sweden)

    Josinéia Gresele Coradini

    2013-06-01

    Full Text Available The aim of this paper was to analyze the body image satisfaction with 24 active elderly women, and to understand the view of these people about the connection between physical exercise and their body image. All of them answered to the scale proposed by Stunkard, Sorenson and Schlusinger, 1983 and to a semi-structured interview. 87.50% of the women were unsatisfied about the body image. From the reading and analysis of the speeches, it was formed two major categories and four subcategories. Thus, most of the elderly women are unsatisfied about their body image, but the proportionate benefits by the exercises are recognized.

  1. Finite Element Based Solution of Laplace's Equation Applied to Electrical Activity of the Human Body

    Directory of Open Access Journals (Sweden)

    Zainab T. Baqer

    2010-01-01

    Full Text Available Computer models are used in the study of electrocardiography to provide insight into physiological phenomena that are difficult to measure in the lab or in a clinical environment. The electrocardiogram is an important tool for the clinician in that it changes characteristically in a number of pathological conditions. Many illnesses can be detected by this measurement. By simulating the electrical activity of the heart one obtains a quantitative relationship between the electrocardiogram and different anomalies. Because of the inhomogeneous fibrous structure of the heart and the irregular geometries of the body, finite element method is used for studying the electrical properties of the heart. This work describes the implementation of the Conjugate Gradient iterative method for the solution of large linear equation systems resulting from the finite element method. A diagonal Jacobi preconditioner is used in order to accelerate the convergence. Gaussian elimination is also implemented and compared with the Precondition Conjugate Gradient (PCG method and with the iterative method. Different types of matrix storage schemes are implemented such as the Compressed Sparse Row (CSR to achieve better performance. In order to demonstrate the validity of the finite element analysis, the technique is adopted to solve Laplace's equation that describes the electrical activity of the human body with Dirichlet and Neumann boundary conditions. An automatic mesh generator is built using C++ programming language. Initially a complete finite element program is built to solve Laplace's equation. The same accuracy is obtained using these methods. The results show that the CSR format reduces computation time compared to the order format. The PCG method is better for the solution of large linear system (sparse matrices than the Gaussian Elimination and back substitution method, while Gaussian elimination is better than iterative method.

  2. Loading and reflexes : the influence of body weight and active movements on reflex responses in humans

    NARCIS (Netherlands)

    Bastiaanse, Catharina Maria

    2003-01-01

    This thesis describes six studies on the influence of active movements and body loading on reflex responses. To measure those influences healthy subjects were asked to walk with different loadings (e.g. a backpack) or with different active movements (e.g. arm swing) while different reflex responses

  3. Forced desynchrony of circadian rhythms of body temperature and activity in rats

    NARCIS (Netherlands)

    Strijkstra, AM; Meerlo, P; Beersma, DGM

    1999-01-01

    The daily rhythm in body temperature is thought to be the result of the direct effects of activity and the effects of an endogenous circadian clock. Forced desynchrony (FD) is a tool used in human circadian rhythm research to disentangle endogenous and activity-related effects on daily rhythms. In t

  4. Body mass indices analysis in the German Giant Ram breed

    Directory of Open Access Journals (Sweden)

    Silvia Patruica

    2015-05-01

    Full Text Available The study of the main body mass indices in the giant German ram breed was performed between 6.06.2014 and 10.06.2014 in a rabbitry from Diniaș town, Timiș County. The biological material was represented by 16 adult rabbit females and 10 adult males, with the average body weight of 7 kg, raised in semi-intensive system. There have been performed the following body measurements: oblique and horizontal length of the trunk, the length of thorax, the length of head, the length of ears, of neck, and of tail, the height at weithers and rump, the height of thorax and stern, the width of chest, of thorax, of rump at hip and ischia, the wide width of forehead, the thoracic circumference and the circumference of shin. Giant German Ram males have registered higher values in the body size index, in the pelvic-thoracic index, and in the rump angle index compared to females from the same breed, which have registered higher values in the index of transverse body size, in the index of massiveness, in the pelvic-thoracic index, and in the cephalic index.

  5. Comparison of variations between percentage of body fat, body mass index and daily physical activity among young Japanese and Thai female students

    Directory of Open Access Journals (Sweden)

    Morinaka Tomoko

    2012-08-01

    Full Text Available Abstract Background In our series of investigations concerning the causes of seasonal change in fat accumulation in young university students, we could not find any contribution of seasonal variation in the ratio of carbohydrate and fat metabolism to that of body fat percentage in Japanese and Thai participants. After our previous study, we examined the effect of daily physical activity on body fat percentage to look for the major causes of seasonal change in fat accumulation in young university students. Findings In this study, we measured participants’ (young Japanese and Thai university students daily physical activity by a uniaxial accelerometer in addition to the measurements of body fat percentage and body mass index by a bioelectrical impedance meter. We found that there was significant and moderate negative correlation between body fat percentage and daily step counts among Japanese but not Thai participants. We observed significant, moderate and positive correlations between the percentage of body fat and body mass index among Japanese and Thai participants. Conclusions Daily physical activity plays an important role in the seasonal variation of body fat percentage of Japanese female students. Our present study also confirmed the importance of daily physical activity for controlling body mass index and for the prevention of obesity.

  6. Predictors of body appearance cognitive distraction during sexual activity in a sample of men with ED.

    Science.gov (United States)

    Pascoal, P M; Raposo, C F; Oliveira, L B

    2015-01-01

    Our aim is to scrutinize the extent to which aspects of body dissatisfaction and relationship variables predict body appearance cognitive distraction during sexual activity (BACDSA) in a sample of men diagnosed with ED. A total of 65 heterosexual Portuguese participants with ED completed a survey that included questions on socio-demographic data as well as body-related and relationship measures. We used the Global Body Dissatisfaction (GBD) Subscale of the Body Attitudes Test; a version of the Contour Drawing Rating Scale; a single item on partner's opinion perceived about one's body appearance; the Global Measure of Relationship Satisfaction; and the Inclusion of Other in Self Scale. Open questions assessed focus on specific body parts during sexual activity and relationship length. Hierarchical multiple regression indicated that only GBD was a significant predictor of BACDSA, contrary to the relationship measures that showed no significant predictive effect (R(2) =0.47). Our results support the important role of individual factors on explanatory models of sexual dysfunctions, suggesting that interventions addressing individual factors that affect BACDSA may be of preference.

  7. DYNAMIC ANALYSIS OF FLEXIBLE BODY WITH DEFINITE MOVING ATTITUTE

    Institute of Scientific and Technical Information of China (English)

    YANG Yuan-ming; ZHANG Wei; SONG Tian-xia; CHEN Chuan-yao

    2006-01-01

    The nonlinear dynamic control equation of a flexible multi-body system with definite moving attitude is discussed. The motion of the aircraft in space is regarded as known and the influence of the flexible structural members in the aircraft on the motion and attitude of the aircraft is analyzed. By means of a hypothetical mode, the deformation of flexible members is regarded as composed of the line element vibration in the axial direction of rectangular coordinates in space. According to Kane's method in dynamics, a dynamic equation is established, which contains the structural stiffness matrix that represents the elastic deformation and the geometric stiffness matrix that represents the nonlinear deformation of the deformed body. Through simplification the dynamic equation of the influence of the planar flexible body with a windsurfboard structure on the spacecraft motion is obtained. The numerical solution for this kind of equation can be realized by a computer.

  8. Sensitivity analysis of random two-body interactions

    CERN Document Server

    Johnson, Calvin W

    2010-01-01

    The input to the configuration-interaction shell model includes many dozens or hundreds of independent two-body matrix elements. Previous studies have shown that when fitting to experimental low-lying spectra, the greatest sensitivity is to only a few linear combinations of matrix elements. Here we consider interactions drawn from the two-body random ensemble, or TBRE, and find that the low-lying spectra are also most sensitive to only a few linear combinations of two-body matrix elements, in a fashion nearly indistinguishable from an interaction empirically fit to data. We find in particular the spectra for both the random and empirical interactions are sensitive to similar matrix elements, which we analyze using monopole and contact interactions.

  9. The proteins of intra-nuclear bodies: a data-driven analysis of sequence, interaction and expression

    Directory of Open Access Journals (Sweden)

    Bodén Mikael

    2010-04-01

    Full Text Available Abstract Background Cajal bodies, nucleoli, PML nuclear bodies, and nuclear speckles are morpohologically distinct intra-nuclear structures that dynamically respond to cellular cues. Such nuclear bodies are hypothesized to play important regulatory roles, e.g. by sequestering and releasing transcription factors in a timely manner. While the nucleolus and nuclear speckles have received more attention experimentally, the PML nuclear body and the Cajal body are still incompletely characterized in terms of their roles and protein complement. Results By collating recent experimentally verified data, we find that almost 1000 proteins in the mouse nuclear proteome are known to associate with one or more of the nuclear bodies. Their gene ontology terms highlight their regulatory roles: splicing is confirmed to be a core activity of speckles and PML nuclear bodies house a range of proteins involved in DNA repair. We train support-vector machines to show that nuclear proteins contain discriminative sequence features that can be used to identify their intra-nuclear body associations. Prediction accuracy is highest for nucleoli and nuclear speckles. The trained models are also used to estimate the full protein complement of each nuclear body. Protein interactions are found primarily to link proteins in the nuclear speckles with proteins from other compartments. Cell cycle expression data provide support for increased activity in nucleoli, nuclear speckles and PML nuclear bodies especially during S and G2 phases. Conclusions The large-scale analysis of the mouse nuclear proteome sheds light on the functional organization of physically embodied intra-nuclear compartments. We observe partial support for the hypothesis that the physical organization of the nucleus mirrors functional modularity. However, we are unable to unambiguously identify proteins' intra-nuclear destination, suggesting that critical drivers behind of intra-nuclear translocation are yet to

  10. Familial lipoprotein lipase-activity deficiency: study of total body fatness and subcutaneous fat tissue distribution.

    Science.gov (United States)

    Brun, L D; Gagné, C; Julien, P; Tremblay, A; Moorjani, S; Bouchard, C; Lupien, P J

    1989-10-01

    Total body fatness and subcutaneous fat tissue distribution were evaluated in 19 hyperchylomicronemic patients. Eleven were males, aged 10 to 57 years, and eight were females, aged 13 to 46 years. Familial lipoprotein-lipase-activity deficiency was diagnosed by the absence of lipoprotein-lipase activity in the plasma withdrawn ten and 20 minutes after intravenous injection of ten units of heparin per kilogram of body weight. The 19 patients had skin-fold measurements for evaluation of subcutaneous fat distribution. Fifteen also underwent body density measurements by underwater weighing. Percent body fat was calculated from body density. These anthropometric data were plotted against the regression curves of 1638 normal controls of both sexes (aged 10 to 54 years) for fat tissue weight, percent body fat, subcutaneous fat/total fat mass ratio and trunk/extremity skin-fold ratio. Impairments in the process of building fat tissue reserves could not be shown in the 19 hyperchylomicronemic patients, in spite of the absence of lipoprotein-lipase activity in their postheparin plasma. It is hypothesized that normal fat tissue mass in these patients could be due partly to de novo synthesis of fatty acids by adipocytes, hydrolysis of plasma triglycerides by hepatic lipase, and/or contribution of a specific fat-tissue lipase to the catabolism of plasma triglyceride-rich lipoproteins.

  11. Analysis of physical activities in Taekwondo Pumsae.

    Science.gov (United States)

    Lee, Sang-Bock; Cha, Eun-Jong; Lee, Tae-Soo

    2008-01-01

    Exercise is very important element for successful aging. Among many sports events, Korea is the suzerain of Taekwondo. When competing (Taekwondo Free Fighting) after learning Poomse as basic movements and inuring them, people compete with movements depending on situation. Among Poomses of Taekwondo, Taegeuk Poomse consists of very basic movements from 1 Jang to 8 Jang and they are for inuring to body. In order to prescribe Taegeuk Jang, which is the basic movement of Taekwondo that Korea is the suzerain, as an exercise for successful aging, it is necessary to analyze physical activity level of each Taegeuk Jang (From 1 Jang through 8 Jang) and suggest the same. Therefore, in this study, I analyzed physical activity level of each Jang of Taegeuk Poomse by attaching Armband made by Body Media Company on brachia and legs below knee of Taekwondo trainees. The result of the analysis of the whole momentum from Taegeuk 1 Jang to 8 Jang is as follows: First, the average absolute value of acceleration variation of vertical direction signal (L-MAD): 5.15. Second, the average absolute value of acceleration variation of horizontal direction signal (T-MAD): 3.44. Finally, the average of calorie consumption per minute (AEE/Min): 5.06 Cal. The obtained result corresponds to proper exercise condition for successful aging and it can be utilized as data for exercise prescription for the young and the old.

  12. A triboelectric motion sensor in wearable body sensor network for human activity recognition.

    Science.gov (United States)

    Hui Huang; Xian Li; Ye Sun

    2016-08-01

    The goal of this study is to design a novel triboelectric motion sensor in wearable body sensor network for human activity recognition. Physical activity recognition is widely used in well-being management, medical diagnosis and rehabilitation. Other than traditional accelerometers, we design a novel wearable sensor system based on triboelectrification. The triboelectric motion sensor can be easily attached to human body and collect motion signals caused by physical activities. The experiments are conducted to collect five common activity data: sitting and standing, walking, climbing upstairs, downstairs, and running. The k-Nearest Neighbor (kNN) clustering algorithm is adopted to recognize these activities and validate the feasibility of this new approach. The results show that our system can perform physical activity recognition with a successful rate over 80% for walking, sitting and standing. The triboelectric structure can also be used as an energy harvester for motion harvesting due to its high output voltage in random low-frequency motion.

  13. Two-body threshold spectral analysis, the critical case

    DEFF Research Database (Denmark)

    Skibsted, Erik; Wang, Xue Ping

    We study in dimension $d\\geq2$ low-energy spectral and scattering asymptotics for two-body $d$-dimensional Schrödinger operators with a radially symmetric potential falling off like $-\\gamma r^{-2},\\;\\gamma>0$. We consider angular momentum sectors, labelled by $l=0,1,\\dots$, for which $\\gamma...

  14. Circadian characteristics of spontaneous physical activity and body temperature in narcoleptic patients

    Directory of Open Access Journals (Sweden)

    Xing XU

    2016-08-01

    Full Text Available Objective To assess circadian characteristics of spontaneous physical activity and deep body temperature in narcoleptic patients.  Methods Fourteen narcoleptic patients and 14 healthy age- and sex-matched control subjects were enrolled. Nocturnal polysomnography (PSG was recorded, followed by standard multiple sleep latency test (MSLT. Then all subjects were required to wear the actigraphy (actiwatch at home with continuous monitoring of spontaneous physical activity for 1-2 weeks and complete the daily sleep record. All subjects' deep body temperatures were measured at 20 time points.  Results In comparison with control subjects, PSG data suggested narcoleptic patients had significantly longer time in bed at night (P = 0.008, decreased sleep efficiency (P = 0.001, increased awakenings (P = 0.000, extended wake time after sleep onset (P = 0.000 and sleep onset rapid eye movement period (SOREMP, P = 0.002. MSLT data suggested decreased average sleep latency (P = 0.000 and increased SOREMPs (P = 0.000. Actigraphy data suggested increased nocturnal activity and nocturnal activity per hour (P = 0.000, for all, decreased daytime activity and daytime activity per hour (P = 0.000, for all and increased nocturnal activity per hour/daytime activity per hour (P = 0.000, for all. The deep body temperature in both groups showed significant circadian rhythms. The differences in mesor, amplitude and peak phase of deep body temperature between 2 groups had no statistical significance (P = 0.177, 0.730, 0.488.  Conclusions Narcoleptic patients are characterized by impaired circadian rhythm of sleep-wake and spontaneous physical activity. The limited effects on deep body temperature suggest the relative conservation of thermoregulation in narcolepsy. DOI: 10.3969/j.issn.1672-6731.2016.07.010

  15. Effects of a single bout of lower-body aerobic exercise on muscle activation and performance during subsequent lower- and upper-body resistance exercise workouts.

    Science.gov (United States)

    Tan, Jeremy G; Coburn, Jared W; Brown, Lee E; Judelson, Daniel A

    2014-05-01

    A single bout of lower-body aerobic exercise may negatively affect a subsequent lower-body resistance exercise workout. However, less is known regarding the effects of a lower-body aerobic workout on muscle activation and performance during a subsequent upper-body resistance exercise workout. Therefore, the purpose of this study was to compare muscle activation and performance during lower- and upper-body resistance exercise workouts after a single bout of lower-body aerobic exercise on an elliptical machine. Fourteen men (mean age = 24.1 ± 2.3 years, height = 180.8 ± 6.9 cm, body mass = 91.9 ± 16.4 kg) completed 4 trials in random order. Two trials consisted of 30 minutes on the elliptical machine, using the lower body only, at 70% of age-predicted maximum heart rate before either a back squat or bench press workout, consisting of 3 sets to failure performed at 75% 1 repetition maximum. The other 2 trials consisted of only the back squat or bench press resistance workouts. To quantify muscle activation, bipolar surface electromyography electrodes were placed on the rectus femoris and vastus lateralis or pectoralis major. Acute lower-body aerobic exercise on an elliptical machine significantly reduced the number of repetitions completed for the back squat but not the bench press exercise. There was no significant difference in muscle activation between the elliptical and no elliptical conditions. However, for both exercises and conditions, muscle activation increased significantly between the first and final repetitions for the first 2 sets but not for the third set. These results suggest that to optimize the quality of a lower-body resistance-training workout, the workout should not be preceded by lower-body aerobic exercise.

  16. Instrumental neutron activation analysis of some ayurvedic medicines: Pt. 1

    Energy Technology Data Exchange (ETDEWEB)

    Rajurkar, N.S.; Vinchurkar, M.S. (Poona Univ., Pune (India). Dept. of Chemistry)

    1992-12-01

    Several medicines have been manufactured and prescribed to overcome mineral deficiencies in the human body. Such medicines are mixtures of several components. The present work is undertaken to analyze various Ayurvedic medicines, mainly of herbal origin and used for different purposes, for their elemental contents, by neutron activation analysis. (author).

  17. Analysis of body water compartments after a short sauna bath using bioelectric impedance analysis.

    Science.gov (United States)

    Servidio, M-F; Mohamed, E I; Maiolo, C; Hereba, A T; Perrone, F; Garofano, P; Iacopino, L

    2003-10-01

    Studies have suggested that long-term sauna bathing may lower blood pressure in persons with hypertension by causing a direct loss of extracellular water and plasma minerals. The objective of the present study was to evaluate the effect of short-term sauna bathing on body water compartments as estimated by bioelectric impedance analysis (BIA). We recruited 15 men [mean age (+/-SD) of 23.93+/-5.12 years and mean body mass index (BMI) of 23.25+/-2.84 kg/m(2)] and 10 women matched for age and BMI. Total body resistance, reactance, and impedance were measured for all participants using BIA, at baseline, after a short sauna bath, and after a rest period. Total, extracellular, and intracellular water compartments were calculated using BIA formulae. There were no significant differences for any of the body water compartments when comparing the measurements taken before and after the sauna bath and after the rest period. However, it remains to be determined whether or not BIA is sensitive to rapid changes in water volume.

  18. RELIABLE ROBUST CONTROLLER FOR HALF-CAR ACTIVE SUSPENSION SYSTEMS BASED ON HUMAN-BODY DYNAMICS

    Directory of Open Access Journals (Sweden)

    Mohammad Gudarzi

    2016-08-01

    Full Text Available The paper investigates a non-fragile robust control strategy for a half-car active suspension system considering human-body dynamics. A 4-DoF uncertain vibration model of the driver’s body is combined with the car’s model in order to make the controller design procedure more accurate. The desired controller is obtained by solving a linear matrix inequality formulation. Then the performance of the active suspension system with the designed controller is compared to the passive one in both frequency and time domain simulations. Finally, the effect of the controller gain variations on the closed-loop system performance is investigated numerically.

  19. The contribution of physical activity and media use during childhood and adolescence to adult women's body image.

    Science.gov (United States)

    Slater, Amy; Tiggemann, Marika

    2006-07-01

    This study aimed to investigate the effects of both past and current physical activity and media use on women's body image. A sample of 144 female undergraduate students completed measures of current physical activity, media use and body image, as well as providing retrospective reports of their physical activity participation and media usage during childhood and adolescence. Regression analyses showed that childhood experiences of physical activity and media use predicted adult body-image concerns more strongly than current activities. It was concluded that early experiences of both physical activity and media use during childhood and adolescence play an important role in the development of adult women's body image.

  20. Promoting fit bodies, healthy eating and physical activity among Indigenous Australian men: a study protocol

    Directory of Open Access Journals (Sweden)

    Ricciardelli Lina A

    2012-01-01

    Full Text Available Abstract Background Overall the physical health of Indigenous men is among the worst in Australia. Research has indicated that modifiable lifestyle factors, such as poor nutrition and physical inactivity, appear to contribute strongly to these poor health conditions. To effectively develop and implement strategies to improve the health of Australia's Indigenous peoples, a greater understanding is needed of how Indigenous men perceive health, and how they view and care for their bodies. Further, a more systematic understanding of how sociocultural factors affect their health attitudes and behaviours is needed. This article presents the study protocol of a community-based investigation into the factors surrounding the health and body image of Indigenous Australian men. Methods and design The study will be conducted in a collaborative manner with Indigenous Australian men using a participatory action research framework. Men will be recruited from three locations around Australia (metropolitan, regional, and rural and interviewed to understand their experiences and perspectives on a number of issues related to health and health behaviour. The information that is collected will be analysed using modified grounded theory and thematic analysis. The results will then be used to develop and implement community events in each location to provide feedback on the findings to the community, promote health enhancing strategies, and determine future action and collaboration. Discussion This study will explore both risk and protective factors that affect the health of Indigenous Australian men. This knowledge will be disseminated to the wider Indigenous community and can be used to inform future health promotion strategies. The expected outcome of this study is therefore an increased understanding of health and health change in Indigenous Australian men, the development of strategies that promote healthy eating and positive patterns of physical activity and, in

  1. Human Deception Detection from Whole Body Motion Analysis

    Science.gov (United States)

    2015-12-01

    development of assessment capabilities of these whole body movements for potential operational deployment. 2 Distribution A: Approved for...upon movement frequencies rather than spatial movement qualities. It was anticipated that, if predictive cues related to the spectral motion...replication analyses of the new samples based on the original findings from Year 1. The findings for the temporal/ spatial data from year 3 provided some

  2. Body Fat and Physical Activity Modulate the Association Between Sarcopenia and Osteoporosis in Elderly Korean Women

    Science.gov (United States)

    Lee, Inhwan; Cho, Jinkyung; Jin, Youngyun; Ha, Changduk; Kim, Taehee; Kang, Hyunsik

    2016-01-01

    This study examined whether modifiable lifestyle factors, such as body fatness and physical activity, modulate the association between sarcopenia and osteoporosis. In a cross-sectional design, 269 postmenopausal women, aged 65 years and older, underwent dual-energy X-ray absorptiometry (DEXA) scans to measure their body fat percentage, total fat mass, total fat-free mass, appendicular lean mass, bone mineral density (BMD) and bone mineral content. The participants wore a uniaxial accelerometer for seven consecutive days to quantify daily physical activity. The collected data were analyzed using descriptive statistics, Pearson correlation, and a binary logistic regression. Pearson correlation analyses showed that total neck/femur BMD was positively associated with weight-adjusted appendicular skeletal muscle mass (ASM) and objectively-measured physical activities. ASM was positively associated with body fatness. Binary logistic regression analyses showed that the odds ratio (OR) of sarcopenia for osteopenia and/or osteoporosis was substantially attenuated but remained marginally significant when adjusted for age and postmenopausal period (OR = 2.370 and p = 0.050). However, the OR was no longer significant when additionally adjusted for body fatness (OR = 2.218 and p = 0.117) and physical activity (OR = 1.240 and p = 0.448). The findings of the study showed that, in this sample of elderly Korean women, modifiable lifestyle risk factors such as body fatness and physical inactivity played an important role in determining the association between sarcopenia and osteopenia/osteoporosis. Key points Osteoporosis and sarcopenia are major health conditions responsible for an increased risk of bone fractures and reduced functional capacity, respectively, in older adults. We investigated whether lifestyle-related risk factors modulate the association between sarcopenia and osteoporosis in older Korean adults. The current findings of the study suggest that physical activity and

  3. Refolding Techniques for Recovering Biologically Active Recombinant Proteins from Inclusion Bodies

    Directory of Open Access Journals (Sweden)

    Hiroshi Yamaguchi

    2014-02-01

    Full Text Available Biologically active proteins are useful for studying the biological functions of genes and for the development of therapeutic drugs and biomaterials in a biotechnology industry. Overexpression of recombinant proteins in bacteria, such as Escherichia coli, often results in the formation of inclusion bodies, which are protein aggregates with non-native conformations. As inclusion bodies contain relatively pure and intact proteins, protein refolding is an important process to obtain active recombinant proteins from inclusion bodies. However, conventional refolding methods, such as dialysis and dilution, are time consuming and, often, recovered yields of active proteins are low, and a trial-and-error process is required to achieve success. Recently, several approaches have been reported to refold these aggregated proteins into an active form. The strategies largely aim at reducing protein aggregation during the refolding procedure. This review focuses on protein refolding techniques using chemical additives and laminar flow in microfluidic chips for the efficient recovery of active proteins from inclusion bodies.

  4. The effect of music video clips on adolescent boys' body image, mood, and schema activation.

    Science.gov (United States)

    Mulgrew, Kate E; Volcevski-Kostas, Diana; Rendell, Peter G

    2014-01-01

    There is limited research that has examined experimentally the effects of muscular images on adolescent boys' body image, with no research specifically examining the effects of music television. The aim of the current study was to examine the effects of viewing muscular and attractive singers in music video clips on early, mid, and late adolescent boys' body image, mood, and schema activation. Participants were 180 boys in grade 7 (mean age = 12.73 years), grade 9 (mean age = 14.40 years) or grade 11 (mean age = 16.15 years) who completed pre- and post-test measures of mood and body satisfaction after viewing music videos containing male singers of muscular or average appearance. They also completed measures of schema activation and social comparison after viewing the clips. The results showed that the boys who viewed the muscular clips reported poorer upper body satisfaction, lower appearance satisfaction, lower happiness, and more depressive feelings compared to boys who viewed the clips depicting singers of average appearance. There was no evidence of increased appearance schema activation but the boys who viewed the muscular clips did report higher levels of social comparison to the singers. The results suggest that music video clips are a powerful form of media in conveying information about the male ideal body shape and that negative effects are found in boys as young as 12 years.

  5. Estimation of physical activity and prevalence of excessive body mass in rural and urban Polish adolescents.

    Science.gov (United States)

    Hoffmann, Karolina; Bryl, Wiesław; Marcinkowski, Jerzy T; Strażyńska, Agata; Pupek-Musialik, Danuta

    2011-01-01

    Excessive body mass and sedentary lifestyle are well-known factors for cardiovascular risk, which when present in the young population may have significant health consequences, both in the short- and long-term. The aim of the study was to evaluate the prevalence of overweight, obesity, and sedentary lifestyle in two teenage populations living in an urban or rural area. An additional aim was to compare their physical activity. The study was designed and conducted in 2009. The study population consisted of 116 students aged 15-17 years - 61 males (52.7%) and 55 females (47.3%), randomly selected from public junior grammar schools and secondary schools in the Poznań Region. There were 61 respondents from a rural area - 32 males (52.5%) and 29 females (47.5%), whereas 55 teenagers lived in an urban area - 29 males (47.5%) and 26 females (47.3%). Students were asked to complete a questionnaire, which was especially prepared for the study and contained questions concerning health and lifestyle. A basic physical examination was carried out in all 116 students, including measurements of the anthropometric features. Calculations were performed using the statistical package STATISTICA (data analysis software system), Version. 8.0. When comparing these two populations, no statistically significant differences were detected in the ratio of weight-growth, with the exception of the fact that the urban youths had a larger hip circumference (97.1 v. 94.3 cm, p0.05), the problem of excessive weight affected both sexes in a similar proportion (25% boys and 24.1% girls, p>0.05). In this paper it is shown that there were differences concerning physical activity of teenagers living in urban and rural areas. Urban students much more often declared an active lifestyle (72.7% v.42.6%, pactivity (not counting compulsory physical education classes).

  6. Active video games: the mediating effect of aerobic fitness on body composition

    Directory of Open Access Journals (Sweden)

    Maddison Ralph

    2012-05-01

    Full Text Available Abstract Background Increased understanding of why and how physical activity impacts on health outcomes is needed to increase the effectiveness of physical activity interventions. A recent randomized controlled trial of an active video game (PlayStation EyeToy™ intervention showed a statistically significant treatment effect on the primary outcome, change from baseline in body mass index (BMI, which favored the intervention group at 24 weeks. In this short paper we evaluate the mediating effects of the secondary outcomes. Objective To identify mediators of the effect of an active video games intervention on body composition. Methods Data from a two-arm parallel randomized controlled trial of an active video game intervention (n = 322 were analyzed. The primary outcome was change from baseline in BMI. A priori secondary outcomes were considered as potential mediators of the intervention on BMI, including aerobic fitness (VO2Max, time spent in moderate-to-vigorous physical activity (MVPA, and food snacking at 24 weeks. Results Only aerobic fitness at 24 weeks met the conditions for mediation, and was a significant mediator of BMI. Conclusion Playing active video games can have a positive effect on body composition in overweight or obese children and this effect is most likely mediated through improved aerobic fitness. Future trials should examine other potential mediators related to this type of intervention. Trial registration Australian New Zealand Clinical Trials Registry Website: http://www.anzctr.org.au Study ID number: ACTRN12607000632493

  7. ORG ANIZATIONAL AND ADMINISTRATIVE ACTIVITIES OF THE HEAD OF THE INVESTIGATIVE BODY, THE BODY OF INQUIRY AND THE HEAD OF THE INVESTIGATION GROUP ON FORMATION AND FUNCTIONING OF THE INVESTIGATIVE TEAM

    Directory of Open Access Journals (Sweden)

    Bastrygin A. S.

    2016-04-01

    Full Text Available The author has analyzed scientific and technical literature, plus materials of judicial and investigative practice, criminal procedural law, different views of scientists, as well as his own judgments on the proposed changes and additions to the content of the article 163 of Criminal Procedure Code. The analysis allows the author to declare the need to invite the heads of the investigative bodies of the various departments and units to carry out more in-depth additional analysis of the items and norms of the criminal procedural law governing the activities of the detective, the head of the investigative body, the head of the investigation team, the investigator, the chief of the inquiry body, the body of inquiry unit and the head of the group of investigators. However, the article 163 of Criminal Procedure Code provides for organizational and administrative activity of the head of the investigative body in terms of decision-making on the establishment of the investigation team, in determining the psychologically compatible, pushing and experienced investigators, members of the investigation team, as well as the approving of the head of the investigative group. Moreover, according to the p. 3 of part 1 of the art. 39 of the Russian Criminal Procedure Code, a head of the investigative body has the right to give instructions about the direction of the investigation and certain investigative actions

  8. Use of bioelectrical impedance analysis to determine body composition changes in HIV-associated wasting.

    Science.gov (United States)

    Klauke, Stephan; Fischer, Harald; Rieger, Armin; Frühauf, Lukas; Staszewski, Schlomo; Althoff, Peter-Henning; Helm, Eilke Brigitte

    2005-04-01

    AIDS wasting syndrome results in loss of lean body mass and body cell mass. This 12-week, open-label study used bioelectrical impedance analysis to measure body composition changes in 24 patients with AIDS wasting syndrome receiving recombinant human growth hormone (r-hGH). The primary endpoint was percentage monthly change in body weight before/after r-hGH. Secondary endpoints included change from baseline in body composition (bioelectrical impedance analysis), isometric strength and CD4+ count. Twenty patients completed the study: r-hGH resulted in mean weight gains (+2.7%, P = 0.146), and significant increases in mean body cell mass (+8.0%, P = 0.0211), lean body mass (+4.8%, P = 0.0373) and water (+5.5%, P r-hGH was generally well tolerated; the most frequent adverse events were fever (7.3%) and diarrhoea (6.3%). Thus, bioelectrical impedance analysis can detect improved body cell mass independent of changes in body weight resulting from r-hGH treatment in patients with AIDS wasting syndrome.

  9. A scaling analysis for thermal fragmentation on small airless bodies

    Science.gov (United States)

    El Mir, Charles; Hazeli, Kavan; Ramesh, KT; Delbo, Marco

    2016-10-01

    The presence of regolith on airless bodies has typically been attributed to impact ejecta re-accumulation and gradual breakdown of boulders by micrometeoritic impacts. However, ejecta velocities for small kilometer-sized asteroids often exceed the gravitational escape velocity, limiting to a great extent the amount of retained debris following a high-velocity impact event. Close-surface images of small (sub-km) asteroid surfaces have shown the presence of a coarse-grained regolith layer on these bodies, suggesting that a different mechanism could be involved in the regolith generation process.Recently, the existence of regolith on sufficiently small planetary bodies has also been attributed to cyclic stresses that develop within boulders due to the large diurnal temperature variation, which eventually lead to fracture by thermal fatigue. It was demonstrated that thermal fatigue can be orders of magnitude faster than fragmentation by classical impact mechanisms, in terms of breaking down cm-sized rocks on small airless bodies. Larger (10 cm-size) rocks were shown to potentially break up faster than smaller (cm) rocks, an observation that is in contrast to the predictions of mechanical disruption models. This observation is justified by the existence of higher internal thermal stresses resulting from the larger temperature gradient in bigger rocks, but it is not clear that this conclusion can be extrapolated or scaled for meter-sized boulders.In the current study, we present a computational and analytical approach that examines thermally driven crack growth within asteroidal rocks over a large range of lengthscales. We first examine the main length and timescales involved in the thermally-driven fatigue crack growth, and identify a critical lengthscale comparable to the thermal skin depth, after which thermal fatigue becomes slower, providing bounds on the thermal fragmentation mechanism. We also develop a simple scaling method to estimate the time required for

  10. Gender-Specific Associations between Personality Traits, Physical Activity, and Body Size Dissatisfaction

    Science.gov (United States)

    Lodewyk, Ken; Sullivan, Philip

    2017-01-01

    A recently validated trait personality framework is the HEXACO (honesty-humility, emotionality, extraversion, agreeableness, conscientiousness, and openness to experience). Little is yet known about how the HEXACO personality dimensions and its subsets--particularly the dimension of honesty-humility--relates to physical activity and body size…

  11. Changes in daily rhythms of body temperature and activity after a single social defeat in rats

    NARCIS (Netherlands)

    Meerlo, P; DeBoer, SF; Koolhaas, JM; Daan, S; VandenHoofdakker, RH

    1996-01-01

    The long-term consequences of social stress on daily rhythms of body temperature and activity in rats were studied by means of radiotelemetry with intraperitoneally implanted transmitters. Rats were subjected to a single social defeat by placing them into the territory of a male conspecific for 1 h.

  12. Creatine Kinase Activity Weakly Correlates to Volume Completed Following Upper Body Resistance Exercise

    Science.gov (United States)

    Machado, Marco; Willardson, Jeffrey M.; Silva, Dailson P.; Frigulha, Italo C.; Koch, Alexander J.; Souza, Sergio C.

    2012-01-01

    In the current study, we examined the relationship between serum creatine kinase (CK) activity following upper body resistance exercise with a 1- or 3-min rest between sets. Twenty men performed two sessions, each consisting of four sets with a 10-repetition maximum load. The results demonstrated significantly greater volume for the 3-min…

  13. Developmental Coordination Disorder, Gender, and Body Weight: Examining the Impact of Participation in Active Play

    Science.gov (United States)

    Cairney, John; Kwan, Matthew Y. W.; Hay, John A.; Faught, Brent E.

    2012-01-01

    Background: To examine whether differences in participation in active play (PAP) can account for gender differences in the relationship between Developmental Coordination Disorder (DCD) and body weight/fat (BMI and percentage fat) in youth. Methods: A cross-sectional investigation of students in grades four through eight (n = 590). Height, weight…

  14. Physical Activity, Body Composition, and Perceived Quality of Life of Adults with Visual Impairments

    Science.gov (United States)

    Holbrook, Elizabeth A.; Caputo, Jennifer L.; Perry, Tara L.; Fuller, Dana K.; Morgan, Don W.

    2009-01-01

    Relatively little is known about the health and fitness of adults with visual impairments. This article documents the physical activity levels and body-composition profiles of young and middle-aged adults with visual impairments and addresses the concomitant effects of these factors on perceived quality of life. (Contains 2 tables.)

  15. Telomere Shortening Unrelated to Smoking, Body Weight, Physical Activity, and Alcohol Intake

    DEFF Research Database (Denmark)

    Weischer, Maren; Bojesen, Stig E; Nordestgaard, Børge G

    2014-01-01

    -year inter-observational tobacco consumption, body weight, physical activity, or alcohol intake. Prospectively during a further 10 years follow-up after the second examination, quartiles of telomere length change did not associate with risk of all-cause mortality, cancer, chronic obstructive pulmonary...

  16. Links between Adolescent Physical Activity, Body Mass Index, and Adolescent and Parent Characteristics

    Science.gov (United States)

    Williams, Susan Lee; Mummery, W. Kerry

    2011-01-01

    Identification of the relationships between adolescent overweight and obesity and physical activity and a range of intrapersonal and interpersonal factors is necessary to develop relevant interventions which target the health needs of adolescents. This study examined adolescent body mass index (BMI) and participation in moderate and vigorous…

  17. Analysis of annual exposure of private farmers to noise and whole body vibration

    Directory of Open Access Journals (Sweden)

    Leszek Solecki

    2012-06-01

    Full Text Available Based on a literature review for the period of 1982– 2011, an analysis was performed of studies by various researchers concerning the exposure of private farmers to noise and vibration of the whole body with particular consideration of the annual exposure to these factors. The main sources of noise occurring in agriculture are: agricultural tractors mounted with a set of farm machinery, self-propelled machines, machinery for the production of fodder and workshop equipment. The review of literature showed that the highest values of equivalent exposure to noise (EA, T or noise doses (d were noted during the summer-autumn season and in spring. Mean noise levels for the entire year (of over 90 dB-A, considerably exceeded permissible values.The primary sources of the whole body vibration are agricultural vehicles including agricultural tractors of various types and self-propelled agricultural vehicles. In these vehicles vibration transmitted from the seat to the whole body is of basic importance. The measurements of vibration acceleration indicated that mechanical vibration on seats was produced while performing following activities: hay tedding and raking, sowing of fertilizers, aggregation of soil, grass mowing and cultivation. All of them may create a considerable health risk. These work activities are performed at elevated working speeds of tractors, most often along with hardened or uneven surfaces. In relation to the standard values (A(840.8 m/s2, the mean daily vibration acceleration values remain below the permissible levels during all months of the year. However, considering the occurrence of mechanical shocks of high values (above the Maximum Acceptable Intensity on agricultural vehicles there is a high risk for the spine problems among operators of agricultural vehicles.

  18. Mining Emerging Sequential Patterns for Activity Recognition in Body Sensor Networks

    DEFF Research Database (Denmark)

    Gu, Tao; Wang, Liang; Chen, Hanhua

    2010-01-01

    Body Sensor Networks oer many applications in healthcare, well-being and entertainment. One of the emerging applications is recognizing activities of daily living. In this paper, we introduce a novel knowledge pattern named Emerging Sequential Pattern (ESP)|a sequential pattern that discovers...... signicant class dierences|to recognize both simple (i.e., sequential) and complex (i.e., interleaved and concurrent) activities. Based on ESPs, we build our complex activity models directly upon the sequential model to recognize both activity types. We conduct comprehensive empirical studies to evaluate...

  19. Is spinal excitability of the triceps surae mainly affected by muscle activity or body position?

    Science.gov (United States)

    Cattagni, T; Martin, A; Scaglioni, G

    2014-06-15

    The aim of this study was to determine how muscle activity and body orientation contribute to the triceps surae spinal transmission modulation, when moving from a sitting to a standing position. Maximal Hoffmann-reflex (Hmax) and motor potential (Mmax) were evoked in the soleus (SOL), medial and lateral gastrocnemius in 10 male subjects and in three conditions, passive sitting, active sitting and upright standing, with the same SOL activity in active sitting and upright standing. Moreover volitional wave (V) was evoked in the two active conditions (i.e., active sitting and upright standing). The results showed that SOL Hmax/Mmax was lower in active sitting than in passive sitting, while for the gastrocnemii it was not significantly altered. For the three plantar flexors, Hmax/Mmax was lower in upright standing than in active sitting, whereas V/Mmax was not modulated. SOL H-reflex is therefore affected by the increase in muscle activity and change in body orientation, while, in the gastrocnemii, it was only affected by a change in posture. In conclusion, passing from a sitting to a standing position affects the Hmax/Mmax of the whole triceps surae, but the mechanisms responsible for this change differ among the synergist muscles. The V/Mmax does not change when upright stance is assumed. This means that the increased inhibitory activity in orthostatic position is compensated by an increased excitatory inflow to the α-motoneurons of central and/or peripheral origin.

  20. Black-body anomaly: analysis of temperature offsets

    Science.gov (United States)

    Szopa, M.; Hofmann, R.; Giacosa, F.; Schwarz, M.

    2008-04-01

    Based on the postulate that photon propagation is governed by a dynamically broken SU(2) gauge symmetry (scale ˜10-4 eV) we make predictions for temperature offsets due to a low-temperature (a few times the present CMB temperature) spectral anomaly at low frequencies. Temperature offsets are extracted from least-square fits of the anomalous black-body spectra to their conventional counterparts. We discuss statistical errors, compare our results with those obtained from calibration data of the FIRAS instrument, and point out that our predicted offsets are screened by experimental errors given the frequency range used by FIRAS to perform their spectral fits. We also make contact with the WMAP observation by blueshifting their frequency bands. Although our results hint towards a strong dynamical component in the CMB dipole and an explanation of low-l suppression, it is important in view of its particle-physics implications that the above postulate be verified/falsified by an independent low-temperature black-body precision experiment.

  1. Embodying analysis: the body and the therapeutic process.

    Science.gov (United States)

    Martini, Salvatore

    2016-02-01

    This paper considers the transfer of somatic effects from patient to analyst, which gives rise to embodied countertransference, functioning as an organ of primitive communication. By means of processes of projective identification, the analyst experiences somatic disturbances within himself or herself that are connected to the split-off complexes of the analysand. The analysty's own attempt at mind-body integration ushers the patient towards a progressive understanding and acceptance of his or her inner suffering. Such experiences of psychic contagion between patient and analyst are related to Jung's 'psychology of the transference' and the idea of the 'subtle body' as an unconscious shared area. The re-attribution of meaning to pre-verbal psychic experiences within the 'embodied reverie' of the analyst enables the analytic dyad to reach the archetypal energies and structuring power of the collective unconscious. A detailed case example is presented of how the emergence of the vitalizing connection between the psyche and the soma, severed through traumatic early relations with parents or carers, allows the instinctual impulse of the Self to manifest, thereby reactivating the process of individuation.

  2. Dairy consumption and insulin resistance: the role of body fat, physical activity, and energy intake.

    Science.gov (United States)

    Tucker, Larry A; Erickson, Andrea; LeCheminant, James D; Bailey, Bruce W

    2015-01-01

    The relationship between dairy consumption and insulin resistance was ascertained in 272 middle-aged, nondiabetic women using a cross-sectional design. Participants kept 7-day, weighed food records to report their diets, including dairy intake. Insulin resistance was assessed using the homeostatic model assessment (HOMA). The Bod Pod was used to measure body fat percentage, and accelerometry for 7 days was used to objectively index physical activity. Regression analysis was used to determine the extent to which mean HOMA levels differed across low, moderate, and high dairy intake categories. Results showed that women in the highest quartile of dairy consumption had significantly greater log-transformed HOMA values (0.41 ± 0.53) than those in the middle-two quartiles (0.22 ± 0.55) or the lowest quartile (0.19 ± 0.58) (F = 6.90, P = 0.0091). The association remained significant after controlling for each potential confounder individually and all covariates simultaneously. Adjusting for differences in energy intake weakened the relationship most, but the association remained significant. Of the 11 potential confounders, only protein intake differed significantly across the dairy categories, with those consuming high dairy also consuming more total protein than their counterparts. Apparently, high dairy intake is a significant predictor of insulin resistance in middle-aged, nondiabetic women.

  3. Dairy Consumption and Insulin Resistance: The Role of Body Fat, Physical Activity, and Energy Intake

    Directory of Open Access Journals (Sweden)

    Larry A. Tucker

    2015-01-01

    Full Text Available The relationship between dairy consumption and insulin resistance was ascertained in 272 middle-aged, nondiabetic women using a cross-sectional design. Participants kept 7-day, weighed food records to report their diets, including dairy intake. Insulin resistance was assessed using the homeostatic model assessment (HOMA. The Bod Pod was used to measure body fat percentage, and accelerometry for 7 days was used to objectively index physical activity. Regression analysis was used to determine the extent to which mean HOMA levels differed across low, moderate, and high dairy intake categories. Results showed that women in the highest quartile of dairy consumption had significantly greater log-transformed HOMA values (0.41 ± 0.53 than those in the middle-two quartiles (0.22 ± 0.55 or the lowest quartile (0.19 ± 0.58 (F = 6.90, P = 0.0091. The association remained significant after controlling for each potential confounder individually and all covariates simultaneously. Adjusting for differences in energy intake weakened the relationship most, but the association remained significant. Of the 11 potential confounders, only protein intake differed significantly across the dairy categories, with those consuming high dairy also consuming more total protein than their counterparts. Apparently, high dairy intake is a significant predictor of insulin resistance in middle-aged, nondiabetic women.

  4. Physical activity, body mass index, and brain atrophy in Alzheimer's disease.

    Science.gov (United States)

    Boyle, Christina P; Raji, Cyrus A; Erickson, Kirk I; Lopez, Oscar L; Becker, James T; Gach, H Michael; Longstreth, W T; Teverovskiy, Leonid; Kuller, Lewis H; Carmichael, Owen T; Thompson, Paul M

    2015-01-01

    The purpose of this study was to use a novel imaging biomarker to assess associations between physical activity (PA), body mass index (BMI), and brain structure in normal aging, mild cognitive impairment, and Alzheimer's dementia. We studied 963 participants (mean age: 74.1 ± 4.4 years) from the multisite Cardiovascular Health Study including healthy controls (n = 724), Alzheimer's dementia patients (n = 104), and people with mild cognitive impairment (n = 135). Volumetric brain images were processed using tensor-based morphometry to analyze regional brain volumes. We regressed the local brain tissue volume on reported PA and computed BMI, and performed conjunction analyses using both variables. Covariates included age, sex, and study site. PA was independently associated with greater whole brain and regional brain volumes and reduced ventricular dilation. People with higher BMI had lower whole brain and regional brain volumes. A PA-BMI conjunction analysis showed brain preservation with PA and volume loss with increased BMI in overlapping brain regions. In one of the largest voxel-based cross-sectional studies to date, PA and lower BMI may be beneficial to the brain across the spectrum of aging and neurodegeneration.

  5. Compensatory activity in the extrastriate body area of Parkinson's disease patients.

    Science.gov (United States)

    van Nuenen, Bart F L; Helmich, Rick C; Buenen, Noud; van de Warrenburg, Bart P C; Bloem, Bastiaan R; Toni, Ivan

    2012-07-11

    Compensatory mechanisms are a crucial component of the cerebral changes triggered by neurodegenerative disorders. Identifying such compensatory mechanisms requires at least two complementary approaches: localizing candidate areas using functional imaging, and showing that interference with these areas has behavioral consequences. Building on recent imaging evidence, we use this approach to test whether a visual region in the human occipito-temporal cortex-the extrastriate body area-compensates for altered dorsal premotor activity in Parkinson's disease (PD) during motor-related processes. We separately inhibited the extrastriate body area and dorsal premotor cortex in 11 PD patients and 12 healthy subjects, using continuous theta burst stimulation. Our goal was to test whether these areas are involved in motor compensatory processes. We used motor imagery to isolate a fundamental element of motor planning, namely subjects' ability to incorporate the current state of their body into a motor plan (mental hand rotation). We quantified this ability through a posture congruency effect (i.e., the improvement in subjects' performance when their current body posture is congruent to the imagined movement). Following inhibition of the right extrastriate body area, the posture congruency effect was lost in PD patients, but not in healthy subjects. In contrast, inhibition of the left dorsal premotor cortex reduced the posture congruency effect in healthy subjects, but not in PD patients. These findings suggest that the right extrastriate body area plays a compensatory role in PD by supporting a function that is no longer performed by the dorsal premotor cortex.

  6. Relationship of Physical Activity Facilitators and Body Mass Index in Kashan Elderly

    Directory of Open Access Journals (Sweden)

    Zahra Khalili

    2015-12-01

    Full Text Available Introduction: There are many factors that affect the level of physical activity and body mass index of the elderly. The current study aimed to assess the relationship of  physical activity facilitators and body mass index of Kashan elderly. Methods: The cross-sectional study sampled 400 elderly older than 60 referred to 10 healthcare centers in Kashan, 2014, via multistage quota method. Participations were tested under demographic characters, body mass index(BMI level, and exercise benefits part of exercise benefits and barrier scale (persian  version for measurig  physical activity facilitators. Data were analyzed in SPSS software, descriptive statistic, Spearman correlation test, Chi-Square and Ordinal regression. Results: Of the participations73.6% were overweight or obese. Median and interquartile range (IQR of  physical activity facilitators was 75 and 33 respectively. The most prominent  physical activity facilitators was" physical activity increases my physical ability, (83.2%. There was a significantly inverse relationship between  physical activity facilitators  score and BMI of participants (r=-0.233, P=0.001. Ordinal regression evealed that mostly predictor of  BMI among  physical activity facilitators was "physical activity improves the quality of my work " (OR=8.683, P=0.001. Conclusion: Results identified  physical activity facilitators directly is related to improve physical circumstances of the elderly people. Surly poviding  physical activity facilitators through educational and interventional programs may improve the health status of aging population.

  7. Bone Mineral Density and Body Composition of Adult Premenopausal Women with Three Levels of Physical Activity

    Directory of Open Access Journals (Sweden)

    Fernando D. Saraví

    2013-01-01

    Full Text Available Weight-bearing and resistance physical activities are recommended for osteoporosis prevention, but it is unclear whether an intensity level above current recommendations has a positive effect on adult premenopausal women. Body composition and bone mineral density (BMD by DXA were compared in three groups of women as follows: Sedentary, Maintenance exercise, and federated Sport Team (n=16 for each group. Physical activity was estimated from the International Physical Activity Questionnaire (IPAQ. The groups did not differ in age, height, weight, or body mass index. Bone mineral content and non-fat soft tissue mass were higher and fat mass was lower in the Sport Team group than in the other groups. The same was true for BMD of total skeleton, lumbar spine, femoral neck, and total hip. A test for linear trend of body composition and BMD showed significant results when including all three groups. Simple and multiple regression analyses showed significant associations between physical activity level (or alternatively, years of participation in programmed physical activity and bone mass measures at all sites except for the middle third of radius. It is concluded that a level of physical activity higher than that usually recommended benefits bone health in adult premenopausal women.

  8. Many-body microhydrodynamics of colloidal particles with active boundary layers

    Science.gov (United States)

    Singh, Rajesh; Ghose, Somdeb; Adhikari, R.

    2015-06-01

    Colloidal particles with active boundary layers—regions surrounding the particles where non-equilibrium processes produce large velocity gradients—are common in many physical, chemical and biological contexts. The velocity or stress at the edge of the boundary layer determines the exterior fluid flow and, hence, the many-body interparticle hydrodynamic interaction. Here, we present a method to compute the many-body hydrodynamic interaction between N spherical active particles induced by their exterior microhydrodynamic flow. First, we use a boundary integral representation of the Stokes equation to eliminate bulk fluid degrees of freedom. Then, we expand the boundary velocities and tractions of the integral representation in an infinite-dimensional basis of tensorial spherical harmonics and, on enforcing boundary conditions in a weak sense on the surface of each particle, obtain a system of linear algebraic equations for the unknown expansion coefficients. The truncation of the infinite series, fixed by the degree of accuracy required, yields a finite linear system that can be solved accurately and efficiently by iterative methods. The solution linearly relates the unknown rigid body motion to the known values of the expansion coefficients, motivating the introduction of propulsion matrices. These matrices completely characterize hydrodynamic interactions in active suspensions just as mobility matrices completely characterize hydrodynamic interactions in passive suspensions. The reduction in the dimensionality of the problem, from a three-dimensional partial differential equation to a two-dimensional integral equation, allows for dynamic simulations of hundreds of thousands of active particles on multi-core computational architectures. In our simulation of 104 active colloidal particle in a harmonic trap, we find that the necessary and sufficient ingredients to obtain steady-state convective currents, the so-called ‘self-assembled pump’, are (a) one-body

  9. Antifreeze Activity of Xylomannan from the Mycelium and Fruit Body of Flammulina velutipes.

    Science.gov (United States)

    Kawahara, Hidehisa; Matsuda, Yoshiyuki; Sakaguchi, Takuya; Arai, Naoki; Koide, Yoshihide

    2016-01-01

    An identified class of antifreeze, a xylomannan-based thermal hysteresis (TH)-producing glycolipid, has been discovered from diverse taxa, including plants, insects, and amphibians. We isolated xylomannan from the mycelium and fruit body of the basidiomycete Flammulina velutipes using successive hot extraction with water, 2% and 25% aqueous KOH, and gel filtration chromatography. The xylomannan from the fruit body had a recrystallization inhibiting (RI) activity (RI=0.44) at 0.5 mg/mL. The dried weight yield of the fruit body (7.7×10(-2)%, w/w) was higher than that of the mycelium. Although the purified xylomannan from both soures were composed of mannose and xylose in a 2 : 1 molar ratio, the molecular weight of the xylomannan from the mycelium and fruit body was 320,000 and 240,000, respectively. The RI activity of mycelial xylomannan was higher than that from the fruit body (RI=0.57) at 45 µg/mL. Although this RI activity was able to remain constant after exposure to various conditions, we confirmed that the decrease of RI activity was stimulated by the decrease of molecular weight that was caused by heating during the alkaline condition. The survival rate of the CHO cells at -20℃ for two days increased to 97% due to the addition of 20 µg/mL of purified xylomannan. This was the first report to indicate that xylomannan from the mycelium of Flammulina velutipes had a high level of ice recrystallization inhibiting activity like antifreeze proteins from plants and had rhe potential to become a new material for cell storage.

  10. INVESTIGETING THE EFFECTS OF STANDING TRAINING ON BODY FUNCTIONS AND ACTIVITY FOR NONAMBULATORY CHILDREN WITH MYELOMENINGOCELE

    Directory of Open Access Journals (Sweden)

    Ozge Cankaya

    2017-09-01

    Full Text Available Background: It was indicated in many studies that verticalization have positive effects such as preventing fractures,regulating cardiopulmonary functions, increasing the head control, and the facilitation of postural muscles in pediatric patients, however, no study showing the effect of supported standing in patients with myelomeningocele on body functions and activity was encountered. The aim of this study is to examine the effects of structured supported standing training in children with myelomeningocele on body functions and activity according to ICF-CY. Methods: Twenty-five children with MMC aged between 3 and 17, who were divided into two groups-SST and control. The supported standing training was given to supported standing group 2 hours a day for 8 weeks in addition to the routine physical therapy program. Body functions were assessed with the Trunk Impairment Scale, and activity levels were assessed with the Gross Motor Function Measurement-88 and Pediatric Functional Independence Measurement at the beginning of the study, at the end of 8 weeks and at the end of 12 weeks from beginning. Results: The results of the structured supported standing training program during 8 weeks showed that children’s body functions and activity increased statistically significantly in SST group (p0.05. Conclusion: The results show that supported standing training effects the body functions and activity positively. It is recommended to educate the families for the supported standing training to be added to the routine physiotherapy and rehabilitation program for children with MMC and continue the training at home.

  11. Moving human full body and body parts detection, tracking, and applications on human activity estimation, walking pattern and face recognition

    Science.gov (United States)

    Chen, Hai-Wen; McGurr, Mike

    2016-05-01

    We have developed a new way for detection and tracking of human full-body and body-parts with color (intensity) patch morphological segmentation and adaptive thresholding for security surveillance cameras. An adaptive threshold scheme has been developed for dealing with body size changes, illumination condition changes, and cross camera parameter changes. Tests with the PETS 2009 and 2014 datasets show that we can obtain high probability of detection and low probability of false alarm for full-body. Test results indicate that our human full-body detection method can considerably outperform the current state-of-the-art methods in both detection performance and computational complexity. Furthermore, in this paper, we have developed several methods using color features for detection and tracking of human body-parts (arms, legs, torso, and head, etc.). For example, we have developed a human skin color sub-patch segmentation algorithm by first conducting a RGB to YIQ transformation and then applying a Subtractive I/Q image Fusion with morphological operations. With this method, we can reliably detect and track human skin color related body-parts such as face, neck, arms, and legs. Reliable body-parts (e.g. head) detection allows us to continuously track the individual person even in the case that multiple closely spaced persons are merged. Accordingly, we have developed a new algorithm to split a merged detection blob back to individual detections based on the detected head positions. Detected body-parts also allow us to extract important local constellation features of the body-parts positions and angles related to the full-body. These features are useful for human walking gait pattern recognition and human pose (e.g. standing or falling down) estimation for potential abnormal behavior and accidental event detection, as evidenced with our experimental tests. Furthermore, based on the reliable head (face) tacking, we have applied a super-resolution algorithm to enhance

  12. Respiratory function, physical activity and body composition in adult rural population

    Directory of Open Access Journals (Sweden)

    Krystyna Rożek-Piechura

    2014-06-01

    Full Text Available objective. The aim of this study was to evaluate functioning of the respiratory system and to estimate the correlation between the function parameters of the respiratory system and the level of physical activity and body composition in the adult rural population. The study involved a group of 116 people from rural population aged 35–60 years, staying on 3-week rehabilitation camps. They were divided into two groups: men (29 and women (87. The somatic features: body height, body weight, Body Mass Index (BMI and body copmposition were analysed, on the status of smoking and declared level of physical activity (PA was checked. For the evaluation of the functional parameters of the respiratory system the pattern of flow volume curve was used. The following parameters were determined: vital capacity (VC, forced vital capacity (FVC, forced expiratory volume in one second (FEV1, peak expiratory flow (PEF, MEF50 (maximum expiratory flow at 50% of VC and Tiffenau index. Hand grip and maximum torque of the knee join flexor and extensor muscles was measured. As expected, men had significantly higher levels of respiratory parameters. In analyzing the status of smoking cigarettes, it can be stated that the majority of subjects are smokers. conclusions. The values of functional parameters of the respiratory system were suitable for the age they were within the norm and did not show lung ventilation disorder. Most subjects of the study declared low physical activity which may be due to manual work on the farm. Smoking cigarettes significantly lowered the value of such parameters as FEV1, PEF and MEF50 only in the male group but the values did not indicate ventilatory disorder. Parameters of the respiratory system show the highest correlations with the parameters of muscle strength. Significant correlations with body compositions parameters (FFM, water have been noticed too.

  13. "BodyWorks": A Parent-Focused Program to Promote Healthful Eating and Physical Activity for Children and Adolescents

    Science.gov (United States)

    Borden, Valerie Melino; Labiner-Wolfe, Judith; Blake, Susan M.; Marr, Amanda; Rowe, Jonelle; Wasserman, Jill

    2012-01-01

    The "BodyWorks" program was designed to help parents improve family eating and activity behaviors. "BodyWorks" was associated with significant gains in parents' knowledge about nutrition and activity, and greater self-efficacy to set family nutrition goals, plan physical activities, and change eating habits. (Contains 1 table.)

  14. Adolescent body satisfaction: the role of perceived parental encouragement for physical activity

    Directory of Open Access Journals (Sweden)

    Downs Danielle

    2009-12-01

    Full Text Available Abstract Background Parents play an important role in the development of children's health behaviors, but less is known about the role of parental encouragement for physical activity (PA on youth PA behavior and body image satisfaction. The purposes of this study were to: (1 longitudinally assess whether adolescent PA at age 15 mediates the effect of perceived parental encouragement for PA at age 15 for predicting adolescent body satisfaction at age 16, while controlling for body mass index (BMI, and (2 examine the extent to which adolescent sex moderates this association. Methods Participants were 379 boys and girls assessed at 15 and 16 years of age, who completed surveys as part of a larger longitudinal study in their health/physical education classes in a school district in Central Pennsylvania. Participants completed measures of their perception of parental encouragement for PA, PA behavior, body satisfaction, and height and weight to calculate BMI at age 15 and 16 (i.e., 10th and 11th grades. Pearson correlations were used to examine the association among the study variables and hierarchical regression analyses were used to predict body satisfaction at age 16. Results Perceived encouragement for PA from fathers, but not mothers, at age 15, was significantly associated with adolescent PA at age 15 and body satisfaction scores at age 16. Adolescents reporting higher PA behavior and perceived encouragement for PA from fathers at age 15 had higher body satisfaction scores at age 16. Moreover, adolescent PA at age 15 mediated the association between perceived fathers' encouragement for PA at age 15 and adolescent body satisfaction at age 16, when controlling for BMI. Examining the moderating effect of adolescent sex on this association revealed that adolescent PA no longer mediated the association between perceived encouragement for PA from fathers and adolescent body satisfaction, and sex moderated this association. Discussion These findings

  15. Some remarks on the stability analysis in Robe's three body problem

    Directory of Open Access Journals (Sweden)

    R. Meire

    1982-01-01

    Full Text Available An improved technique is presented for the stability analysis of Robe's 3-body problem which gives more accurate results for the transition curves in the parameter plane than does Robe's paper.

  16. Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies.

    Directory of Open Access Journals (Sweden)

    Hua-Bing Li

    2013-04-01

    Full Text Available Polycomb bodies are foci of Polycomb proteins in which different Polycomb target genes are thought to co-localize in the nucleus, looping out from their chromosomal context. We have shown previously that insulators, not Polycomb response elements (PREs, mediate associations among Polycomb Group (PcG targets to form Polycomb bodies. Here we use live imaging and 3C interactions to show that transgenes containing PREs and endogenous PcG-regulated genes are targeted by insulator proteins to different nuclear structures depending on their state of activity. When two genes are repressed, they co-localize in Polycomb bodies. When both are active, they are targeted to transcription factories in a fashion dependent on Trithorax and enhancer specificity as well as the insulator protein CTCF. In the absence of CTCF, assembly of Polycomb bodies is essentially reduced to those representing genomic clusters of Polycomb target genes. The critical role of Trithorax suggests that stable association with a specialized transcription factory underlies the cellular memory of the active state.

  17. Real-time Human Activity Recognition using a Body Sensor Network

    DEFF Research Database (Denmark)

    Wang, Liang; Gu, Tao; Chen, Hanhua

    2010-01-01

    . In this model, we first use a fast, lightweight template matching algorithm to detect gestures at the sensor node level, and then use a discriminative pattern based real-time algorithm to recognize high-level activities at the portable device level. We evaluate our algorithms over a real-world dataset......Real-time activity recognition using body sensor networks is an important and challenging task and it has many potential applications. In this paper, we propose a realtime, hierarchical model to recognize both simple gestures and complex activities using a wireless body sensor network....... The results show that the proposed system not only achieves good performance (an average precision of 94.9%, an average recall of 82.5%, and an average real-time delay of 5.7 seconds), but also significantly reduces the network communication cost by 60.2%....

  18. Modification effects of physical activity and protein intake on heritability of body size and composition

    DEFF Research Database (Denmark)

    Silventoinen, Karri; Hasselbalch, Ann Louise; Lallukka, Tea

    2009-01-01

    BACKGROUND: The development of obesity is still a poorly understood process that is dependent on both genetic and environmental factors. OBJECTIVE: The objective was to examine how physical activity and the proportion of energy as protein in the diet modify the genetic variation of body mass index....... The participants reported the frequency and intensity of their leisure time physical activity. Waist circumference and BMI were measured. Percentage body fat was assessed in Denmark by using a bioelectrical impedance method. The data were analyzed by using gene-environment interaction models for twin data...... with the Mx statistical package (Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA). RESULTS: High physical activity was associated with lower mean values, and a high proportion of protein in the diet was associated with higher mean BMI, waist...

  19. Musculoskeletal disorders in construction: A review and a novel system for activity tracking with body area network.

    Science.gov (United States)

    Valero, Enrique; Sivanathan, Aparajithan; Bosché, Frédéric; Abdel-Wahab, Mohamed

    2016-05-01

    Human body motions have been analysed for decades with a view on enhancing occupational well-being and performance of workers. On-going progresses in miniaturised wearable sensors are set to revolutionise biomechanical analysis by providing accurate and real-time quantitative motion data. The construction industry has a poor record of occupational health, in particular with regard to work-related musculoskeletal disorders (WMSDs). In this article, we therefore focus on the study of human body motions that could cause WMSDs in construction-related activities. We first present an in-depth review of existing assessment frameworks used in practice for the evaluation of human body motion. Subsequently different methods for measuring working postures and motions are reviewed and compared, pointing out the technological developments, limitations and gaps; Inertial Measurement Units (IMUs) are particularly investigated. Finally, we introduce a new system to detect and characterise unsafe postures of construction workers based on the measurement of motion data from wearable wireless IMUs integrated in a body area network. The potential of this system is demonstrated through experiments conducts in a laboratory as well as in a college with actual construction trade trainees.

  20. The Body Action Coding System II: Muscle activations during the perception and expression of emotion

    Directory of Open Access Journals (Sweden)

    Elisabeth M.J. Huis in 't Veld

    2014-09-01

    Full Text Available Research into the expression and perception of emotions has mostly focused on facial expressions. Recently, body postures have become increasingly important in research, but knowledge on muscle activity during the perception or expression of emotion is lacking. The current study continues the development of a Body Action Coding System (BACS, which was initiated in a previous study, and described the involvement of muscles in the neck, shoulders and arms during expression of fear and anger. The current study expands the BACS by assessing the activity patterns of three additional muscles. Surface electromyography of muscles in the neck (upper trapezius descendens, forearms (extensor carpi ulnaris, lower back (erector spinae longissimus and calves (peroneus longus were measured during active expression and passive viewing of fearful and angry body expressions. The muscles in the forearm were strongly active for anger expression and to a lesser extent for fear expression. In contrast, muscles in the calves were recruited slightly more for fearful expressions. It was also found that muscles automatically responded to the perception of emotion, without any overt movement. The observer’s forearms responded to the perception of fear, while the muscles used for leaning backwards were activated when faced with an angry adversary. Lastly, the calf responded immediately when a fearful person was seen, but responded slower to anger. There is increasing interest in developing systems that are able to create or recognize emotional body language for the development of avatars, robots, and online environments. To that end, multiple coding systems have been developed that can either interpret or create bodily expressions based on static postures, motion capture data or videos. However, the BACS is the first coding system based on muscle activity.

  1. The Body Action Coding System II: muscle activations during the perception and expression of emotion.

    Science.gov (United States)

    Huis In 't Veld, Elisabeth M J; van Boxtel, Geert J M; de Gelder, Beatrice

    2014-01-01

    Research into the expression and perception of emotions has mostly focused on facial expressions. Recently, body postures have become increasingly important in research, but knowledge on muscle activity during the perception or expression of emotion is lacking. The current study continues the development of a Body Action Coding System (BACS), which was initiated in a previous study, and described the involvement of muscles in the neck, shoulders and arms during expression of fear and anger. The current study expands the BACS by assessing the activity patterns of three additional muscles. Surface electromyography of muscles in the neck (upper trapezius descendens), forearms (extensor carpi ulnaris), lower back (erector spinae longissimus) and calves (peroneus longus) were measured during active expression and passive viewing of fearful and angry body expressions. The muscles in the forearm were strongly active for anger expression and to a lesser extent for fear expression. In contrast, muscles in the calves were recruited slightly more for fearful expressions. It was also found that muscles automatically responded to the perception of emotion, without any overt movement. The observer's forearms responded to the perception of fear, while the muscles used for leaning backwards were activated when faced with an angry adversary. Lastly, the calf responded immediately when a fearful person was seen, but responded slower to anger. There is increasing interest in developing systems that are able to create or recognize emotional body language for the development of avatars, robots, and online environments. To that end, multiple coding systems have been developed that can either interpret or create bodily expressions based on static postures, motion capture data or videos. However, the BACS is the first coding system based on muscle activity.

  2. Modulation of anticipatory postural activity for multiple conditions of a whole-body pointing task.

    Science.gov (United States)

    Tolambiya, A; Chiovetto, E; Pozzo, T; Thomas, E

    2012-05-17

    This is a study on associated postural activities during the anticipatory segments of a multijoint movement. Several previous studies have shown that they are task dependant. The previous studies, however, have mostly been limited in demonstrating the presence of modulation for one task condition, that is, one aspect such as the distance of the target or the direction of reaching. Real-life activities like whole-body pointing, however, can vary in several ways. How specific is the adaptation of the postural activities for the diverse possibilities of a whole-body pointing task? We used a classification paradigm to answer this question. We examined the anticipatory postural electromyograms for four different types of whole-body pointing tasks. The presence of task-dependent modulations in these signals was probed by performing four-way classification tests using a support vector machine (SVM). The SVM was able to achieve significantly higher than chance performance in correctly predicting the movements at hand (Chance performance 25%). Using only anticipatory postural muscle activity, the correct movement at hand was predicted with a mean rate of 62%. Because this is 37% above chance performance, it suggests the presence of postural modulation for diverse conditions. The anticipatory activities consisted of both activations and deactivations. Movement prediction with the use of the activating muscles was significantly better than that obtained with the deactivating muscles. This suggests that more specific modulations for the movement at hand take place through activation, whereas the deactivation is more general. The study introduces a new method for investigating adaptations in motor control. It also sheds new light on the quantity and quality of information available in the feedforward segments of a voluntary multijoint motor activity.

  3. Animal physiology. Summer declines in activity and body temperature offer polar bears limited energy savings.

    Science.gov (United States)

    Whiteman, J P; Harlow, H J; Durner, G M; Anderson-Sprecher, R; Albeke, S E; Regehr, E V; Amstrup, S C; Ben-David, M

    2015-07-17

    Polar bears (Ursus maritimus) summer on the sea ice or, where it melts, on shore. Although the physiology of "ice" bears in summer is unknown, "shore" bears purportedly minimize energy losses by entering a hibernation-like state when deprived of food. Such a strategy could partially compensate for the loss of on-ice foraging opportunities caused by climate change. However, here we report gradual, moderate declines in activity and body temperature of both shore and ice bears in summer, resembling energy expenditures typical of fasting, nonhibernating mammals. Also, we found that to avoid unsustainable heat loss while swimming, bears employed unusual heterothermy of the body core. Thus, although well adapted to seasonal ice melt, polar bears appear susceptible to deleterious declines in body condition during the lengthening period of summer food deprivation.

  4. Body side-specific control of motor activity during turning in a walking animal.

    Science.gov (United States)

    Gruhn, Matthias; Rosenbaum, Philipp; Bockemühl, Till; Büschges, Ansgar

    2016-04-27

    Animals and humans need to move deftly and flexibly to adapt to environmental demands. Despite a large body of work on the neural control of walking in invertebrates and vertebrates alike, the mechanisms underlying the motor flexibility that is needed to adjust the motor behavior remain largely unknown. Here, we investigated optomotor-induced turning and the neuronal mechanisms underlying the differences between the leg movements of the two body sides in the stick insect Carausius morosus. We present data to show that the generation of turning kinematics in an insect are the combined result of descending unilateral commands that change the leg motor output via task-specific modifications in the processing of local sensory feedback as well as modification of the activity of local central pattern generating networks in a body-side-specific way. To our knowledge, this is the first study to demonstrate the specificity of such modifications in a defined motor task.

  5. The Study of Some Cracks on the Panels of a Minibus Body Using Modal Analysis

    Science.gov (United States)

    Iozsa, D.; Micu, D. A.

    2016-11-01

    The body vibrations caused by the disturbing forces which acts on this one cause many problems connected, generaly, with the passengers confort (mechanical vibrations, noises) and also connected with the body reliability. The paper presents the study of some craks appeared on the roof panels of the body of a minibus and the study of some attempts to improve the behaviour. The study was made using the modal analysis in two steps. First was studied the behaviour of the hole structure and than was studied only the panel where cracks appear. The analysis of the first four eigenmodes confirmed cause of the cracks. Finally, it was offered an improved solution.

  6. Study on Dimension Chain Generation for Auto-body Tolerance Analysis

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    For auto-body product, assembly dimensional quality evaluation using tolerance analysis method is a challenging task because there are plenty of elements impacting on the variation stack-up and propagation during assembly process. Traditional method of dimension chain generation based on tolerance charting technique can not suit the case of auto-body assembly. This paper proposed a method to generate dimension chain based on developing a jot chain model of assembly, which can be integrated with important information needed for variation analysis, such as joints types and assembly sequences. The implementation of such a procedure will contribute to rapid evaluation of body dimensional quality in the design stage.

  7. Viewing the motion of human body parts activates different regions of premotor, temporal, and parietal cortex.

    Science.gov (United States)

    Wheaton, Kylie J; Thompson, James C; Syngeniotis, Ari; Abbott, David F; Puce, Aina

    2004-05-01

    Activation of premotor and temporoparietal cortex occurs when we observe others movements, particularly relating to objects. Viewing the motion of different body parts without the context of an object has not been systematically evaluated. During a 3T fMRI study, 12 healthy subjects viewed human face, hand, and leg motion, which was not directed at or did not involve an object. Activation was identified relative to static images of the same human face, hand, and leg in both individual subject and group average data. Four clear activation foci emerged: (1) right MT/V5 activated to all forms of viewed motion; (2) right STS activated to face and leg motion; (3) ventral premotor cortex activated to face, hand, and leg motion in the right hemisphere and to leg motion in the left hemisphere; and (4) anterior intraparietal cortex (aIP) was active bilaterally to viewing hand motion and in the right hemisphere leg motion. In addition, in the group data, a somatotopic activation pattern for viewing face, hand, and leg motion occurred in right ventral premotor cortex. Activation patterns in STS and aIP were more complex--typically activation foci to viewing two types of human motion showed some overlap. Activation in individual subjects was similar; however, activation to hand motion also occurred in the STS with a variable location across subjects--explaining the lack of a clear activation focus in the group data. The data indicate that there are selective responses to viewing motion of different body parts in the human brain that are independent of object or tool use.

  8. Technical activity profile and influence of body anthropometry on playing performance in female elite team handball

    DEFF Research Database (Denmark)

    Michalsik, Lars B; Aagaard, Per; Madsen, Klavs

    2015-01-01

    To determine the physical demands placed on female elite team handball (TH) players in relation to playing position and body anthropometry, female elite TH primarily field players were monitored during match-play using video recording and subsequent computerized technical match analysis during 5.......4 screenings, received 14.6 ± 9.2 tackles in total, and performed 7.7 ± 3.7 shots while in offense, along with 3.5 ± 3.8 blockings, 1.9 ± 2.7 claspings, and 6.2 ± 3.8 hard tackles in defense. Mean body height, body mass, and age in the Danish Premier Female Team Handball League were 175.4 ± 6.1 cm, 69.5 ± 6...

  9. Black-Body Anomaly: Analysis of Temperature Offsets

    CERN Document Server

    Szopa, Michal; Giacosa, Francesco; Schwarz, Markus

    2007-01-01

    Based on the postulate that photon propagation is governed by a dynamically broken SU(2) gauge symmetry (scale $\\sim 10^{-4} $eV) we make predictions for temperature offsets due to a low-temperature (a few times the present CMB temperature) spectral anomaly at low frequencies. Temperature offsets are extracted from least-square fits of the anomalous black-body spectra to their conventional counterparts. We discuss statistical errors, compare our results with those obtained from calibration data of the FIRAS instrument, and point out that our predicted offsets are screened by experimental errors given the frequency range used by FIRAS to perform their spectral fits. We also make contact with the WMAP observation by blueshifting their frequency bands. Although our results hint towards a strong dynamical component in the CMB dipole and an explanation of low-$l$ suppression it is important in view of its particle-physics implications that the above postulate be verified/falsified by an independent low-temperature...

  10. Three-Body Model Analysis of Subbarrier alpha Transfer Reaction

    CERN Document Server

    Fukui, Tokuro; Yahiro, Masanobu

    2011-01-01

    Subbarrier alpha transfer reaction 13C(6Li,d)17O(6.356 MeV, 1/2+) at 3.6 MeV is analyzed with a alpha + d + 13C three-body model, and the asymptotic normalization coefficient (ANC) for alpha + 13C --> 17O(6.356 MeV, 1/2+), which essentially determines the reaction rate of 13C(alpha,n)16O, is extracted. Breakup effects of 6Li in the initial channel and those of 17O in the final channel are investigated with the continuum-discretized coupled-channels method (CDCC). The former is found to have a large back-coupling to the elastic channel, while the latter turns out significantly small. The transfer cross section calculated with Born approximation to the transition operator, including breakup states of 6Li, gives (C_{alpha 13C}{17O*})^2 =1.03 \\pm 0.29 fm^{-1}. This result is consistent with the value obtained by the previous DWBA calculation.

  11. Relationship of serum somatomedin-like activity and fibroblast proliferative activity with age and body weight gain in sheep.

    Science.gov (United States)

    Olsen, R F; Wangsness, P J; Patton, W H; Martin, R J

    1981-01-01

    The relationship between serum growth factors and body weight gain was examined in five Dorset lambs. The lambs were weighed and bled by jugular puncture at 2-week intervals between 2 and 18 weeks of age. Somatomedin-like activity (Sm) declined from initially high concentrations at 2 weeks to fairly constant concentrations between 6 and 18 weeks. Relative weight gain--i.e., gain expressed as a percentage of body weight--declined in a manner similar to that of Sm. Mean relative weight gain and mean Sm for the eight 2-week intervals were significantly related (r = .84). Absolute body weight gain--i.e., gain expressed in kilograms--remained fairly constant throughout the study and was not significantly correlated to Sm (r = .15). Serum fibroblast proliferative activity (FPA) was measured as a possible indicator of collective activities of serum growth factors. FPA initially followed a pattern similar to that of Sm, decreasing between 2 and 6 weeks and plateauing until 12 weeks. After 12 weeks, FPA increased to concentrations similar to those observed at 2 weeks. The increase in FPA after 12 weeks was apparently due to an increase in a non-Sm growth factor and had no obvious relationship to body weight changes. Results of the in vitro cell assay system might have been more meaningful if cell type(s) other than WI-38 fibroblasts (e.g., myogenic cells) had been used for estimating collective activities of serum mitogenic factors. The data suggest that serum Sm-like activity may be important in the regulation of growth in sheep.

  12. Health perceptions, self and body image, physical activity and nutrition among undergraduate students in Israel.

    Directory of Open Access Journals (Sweden)

    Liat Korn

    Full Text Available PURPOSE: This study examines health perceptions, self and body image, physical exercise and nutrition among undergraduate students. METHODS: A structured, self-reported questionnaire was administered to more than 1500 students at a large academic institute in Israel. The study population was heterogenic in both gender and fields of academic study. RESULTS: High correlations between health perceptions, appropriate nutrition, and positive self and body image were found. The relationships between these variables differed between the subpopulation in the sample and the different genders. Engagement in physical exercise contributed to positive body image and positive health perceptions more than engagement in healthy nutrition. Nutrition students reported higher frequencies of positive health perceptions, positive self and body image and higher engagement in physical exercise in comparison to all other students in the sample. CONCLUSIONS: This study suggests, as have many before, that successful health promotion policy should reflect a collectivist rather than an individualist ethos by providing health prerequisites through a public policy of health-promotion, where the academic settings support a healthy lifestyle policy, by increasing availability of a healthy, nutritious and varied menu in the cafeterias, and offering students various activities that enhance healthy eating and exercise. IMPLICATIONS AND CONTRIBUTION: This study examined health perceptions, self-image, physical exercise and nutrition among undergraduate students and found high correlations between these topics. Nutrition students reported higher frequencies of positive health perceptions, and positive self and body image and engaged more in physical exercise when compared with all other students in the sample.

  13. Assessment of body composition by dual-energy X-ray absorptiometry, bioimpedance analysis and anthropometrics in children

    DEFF Research Database (Denmark)

    Tompuri, Tuomo T; Lakka, Timo A; Hakulinen, Mikko;

    2015-01-01

    We compared InBody720 segmental multifrequency bioimpedance analysis (SMF-BIA) with Lunar Prodigy Advance dual-energy X-ray absorptiometry (DXA) in assessment of body composition among 178 predominantly prepubertal children. Segmental agreement analysis of body compartments was carried out, and i......, and inter-relationships of anthropometric and other measures of body composition were defined. Moreover, the relations of different reference criteria for excess body fat were evaluated....

  14. The neural basis of body form and body action agnosia.

    Science.gov (United States)

    Moro, Valentina; Urgesi, Cosimo; Pernigo, Simone; Lanteri, Paola; Pazzaglia, Mariella; Aglioti, Salvatore Maria

    2008-10-23

    Visual analysis of faces and nonfacial body stimuli brings about neural activity in different cortical areas. Moreover, processing body form and body action relies on distinct neural substrates. Although brain lesion studies show specific face processing deficits, neuropsychological evidence for defective recognition of nonfacial body parts is lacking. By combining psychophysics studies with lesion-mapping techniques, we found that lesions of ventromedial, occipitotemporal areas induce face and body recognition deficits while lesions involving extrastriate body area seem causatively associated with impaired recognition of body but not of face and object stimuli. We also found that body form and body action recognition deficits can be double dissociated and are causatively associated with lesions to extrastriate body area and ventral premotor cortex, respectively. Our study reports two category-specific visual deficits, called body form and body action agnosia, and highlights their neural underpinnings.

  15. Body Massage Performance Investigation by Brain Activity Analysis

    Directory of Open Access Journals (Sweden)

    Kang-Ming Chang

    2012-01-01

    Full Text Available Massage has been widely applied to improve health and reduce stress. However, the performance difference between hands-on treatment and treatment by mechanical devices has been little mentioned. Therefore, the main aim of this paper is to investigate a subject's EEG performance under massage treatment applied by hand and treatment applied by mechanical devices. Massage was applied to four acupoints for three minutes each. The massage acupoint sequence was from left Jian-wai-yu, right Jian-wai-yu, left Zuo-fei-yu, and finally right Zuo-fei-yu. An EEG system of 32 channels was used. Twenty-four volunteers, mainly college students, were enrolled. EEG rhythm powers of each massage sessions were derived. Two-way ANOVA revealed that there were also significant interactions between the massage stage and the massage type on delta (P<0.01, theta (P<0.05, and beta rhythms (P<0.01, and there were significant differences at different stages for the mechanical massage group (F=5.557, P<0.01. The mechanical massage group had more significant differences than the hands-on group for stage coherence of around coherence on alpha rhythm. Further rhythm power scalp topography between two massage methods is also investigated.

  16. Ring-element analysis of layered orthotropic bodies

    DEFF Research Database (Denmark)

    Jørgensen, O.

    1993-01-01

    to be determined in the finite element analysis. The element chosen is an eight node isoparametric element of the serendipity family. The Fourier series show very high rate of convergence for the problems solved. The investigation shows that the computational work is remarkably reduced in relation...

  17. Antioxidant activity of water extracts from fruit body of Lentinus edodes enriched with selenium

    Directory of Open Access Journals (Sweden)

    Savić Milena D.

    2011-01-01

    Full Text Available Shiitake (Lentinus edodes belongs to medically important and delicious fungi. It is recognizable for its healing properties, excellent taste and rich aroma. According to the traditional Japanese and Chinese medicine, shiitake mushroom significantly increases the strength and vitality of the body. Shiitake contains immunostimulants, compounds that lower cholesterol, prevents clogging of blood vessels, regulates the pressure, balances blood sugar levels, regulates digestion, and improves the performance of respiratory organs by its antirheumatic and antiallergic activities. Shiitake is recommended to use as food, prevention and cure, usually in a form of a spice (dried and ground or tea. It can be consumed fresh, too. The objective of this study was to test the effect of enrichment in selenium on antioxidant, reducing and free radical scavenging activity of water extracts from fruit body of Lentinus edodes. The fungus was enhanced by adding organic selenium, zinc (II complex with the ligand 2.6-bis diacetylpyridine (selenosemicarbazon and inorganic compounds (Na2SeO3 of selenium in nutritional substrate where the fungus was grown. The total selenium content in fruit body was around 50 ppm for the sample enriched with selenium originating from organic sources, and 80 ppm for the sample enriched with selenium from inorganic sources. Samples were prepared by extraction of fruiting bodies in heated water. The results indicated that water extracts of whole fruit bodies, from both control and mushrooms supplemented with selenium, had quite good antioxidant activity. However, there was no significant difference between the samples supplemented with selenium content and those that were not.

  18. Weight-bearing physical activity, calcium intake, systemic glucocorticoids, chronic inflammation, and body constitution as determinants of lumbar and femoral bone mineral in juvenile chronic arthritis.

    Science.gov (United States)

    Kotaniemi, A; Savolainen, A; Kröger, H; Kautiainen, H; Isomäki, H

    1999-01-01

    The associations between the lumbar and femoral bone mineral and several body constitutional, lifestyle, and disease related variables were studied in 111 children with juvenile chronic arthritis (JCA) by factor and multiple linear regression analyses. In addition to the measurement of bone mineral density (BMD), bone width and bone mineral volumetric density (BMDvol) were determined by dual-x-ray absorptiometry (DXA). Factor analysis of 13 explanatory variables yielded six non-correlating factors, named as body size, physical activity, calcium intake, glucocorticoids, disease duration, and disease activity. These six factors were used as new variables to explain BMD, BMDvol, and bone width by multiple linear regression analyses. These showed body size, physical activity, and calcium intake as significant positive and disease activity and glucocorticoids as significant negative determinants of BMD in JCA. The analyses revealed also considerable differences in the relationships between factors and BM Dvol or bone width.

  19. Is Being a Boy and Feeling Fat a Barrier for Physical Activity? The Association between Body Image, Gender and Physical Activity among Adolescents

    NARCIS (Netherlands)

    Kopcakova, Jaroslava; Veselska, Zuzana Dankulincova; Geckova, Andrea Madarasova; van Dijk, Jitse P.; Reijneveld, Sijmen A.

    2014-01-01

    Regular physical activity leads to physical and mental health benefits. Previous studies have shown physical activity to be associated with body image and gender. The aim of this cross-sectional study was to explore the associations of body image with physical activity of adolescents and whether gen

  20. [Role of oxytocin in activation of spontaneous electrical activity of uterine body and uterine tubes in non-pregnant rats].

    Science.gov (United States)

    Kazarian, K V; Unanian, N G; Meliksetian, I B; Akopian, R R; Saakian, A A

    2011-01-01

    The work studies effects of various doses of oxytocin (0.01, 0.1, 1 and 10 microg/kg) on duration of discharges of spontaneous electrical activity and frequency of spikes in various parts of uterine tubes and of uterine body of non-pregnant rats. Under these conditions, changes in these parameters for ovarian parts of the uterine tubes had similar character unlike those in cervical parts of the tubes and in the middle part of the uterine body, so the latter parts can be grouped together owing to peculiarities of their changes. The longest duration of genesis of electric discharges has been shown for the ovarian part of uterine tubes at a concentration of 10 microg/kg of oxytocin. Morphological experiments revealed that among all studies areas the ovarian parts of uterine tubes were characterized by the highest amount of atypical cells that have the maximally pronounced functional activity.

  1. Influence of Hatha yoga on physical activity constraints, physical fitness, and body image of breast cancer survivors: a pilot study.

    Science.gov (United States)

    Van Puymbroeck, Marieke; Schmid, Arlene; Shinew, Kimberly J; Hsieh, Pei-Chun

    2011-01-01

    Breast cancer survivors often experience changes in their perception of their bodies following surgical treatment. These changes in body image may increase self-consciousness and perceptions of physical activity constraints and reduce participation in physical activity. While the number of studies examining different types of yoga targeting women with breast cancer has increased, studies thus far have not studied the influence that Hatha yoga has on body image and physical activity constraints. The objective of this study was to explore the changes that occur in breast cancer survivors in terms of body image, perceived constraints, and physical fitness following an 8-week Hatha yoga intervention. This study used a nonrandomized two-group pilot study, comparing an 8-week Hatha yoga intervention with a light exercise group, both designed for women who were at least nine months post-treatment for breast cancer. Both quantitative and qualitative data were collected in the areas of body image, physical activity constraints, and physical fitness. Findings indicated that quantitatively, yoga participants experienced reductions in physical activity constraints and improvements in lower- and upper-body strength and flexibility, while control participants experienced improvements in abdominal strength and lower-body strength. Qualitative findings support changes in body image, physical activity constraints, and physical fitness for the participants in the yoga group. In conclusion, Hatha yoga may reduce constraints to physical activity and improve fitness in breast cancer survivors. More research is needed to explore the relationship between Hatha yoga and improvements in body image.

  2. Learning dictionaries of sparse codes of 3D movements of body joints for real-time human activity understanding.

    Directory of Open Access Journals (Sweden)

    Jin Qi

    Full Text Available Real-time human activity recognition is essential for human-robot interactions for assisted healthy independent living. Most previous work in this area is performed on traditional two-dimensional (2D videos and both global and local methods have been used. Since 2D videos are sensitive to changes of lighting condition, view angle, and scale, researchers begun to explore applications of 3D information in human activity understanding in recently years. Unfortunately, features that work well on 2D videos usually don't perform well on 3D videos and there is no consensus on what 3D features should be used. Here we propose a model of human activity recognition based on 3D movements of body joints. Our method has three steps, learning dictionaries of sparse codes of 3D movements of joints, sparse coding, and classification. In the first step, space-time volumes of 3D movements of body joints are obtained via dense sampling and independent component analysis is then performed to construct a dictionary of sparse codes for each activity. In the second step, the space-time volumes are projected to the dictionaries and a set of sparse histograms of the projection coefficients are constructed as feature representations of the activities. Finally, the sparse histograms are used as inputs to a support vector machine to recognize human activities. We tested this model on three databases of human activities and found that it outperforms the state-of-the-art algorithms. Thus, this model can be used for real-time human activity recognition in many applications.

  3. Towards an understanding of regulating Cajal body activity by protein modification.

    Science.gov (United States)

    Hebert, Michael D; Poole, Aaron R

    2016-10-07

    The biogenesis of small nuclear ribonucleoproteins (snRNPs), small Cajal body-specific RNPs (scaRNPs), small nucleolar RNPs (snoRNPs) and the telomerase RNP involves Cajal bodies (CBs). Although many components enriched in the CB contain post-translational modifications (PTMs), little is known about how these modifications impact individual protein function within the CB and, in concert with other modified factors, collectively regulate CB activity. Since all components of the CB also reside in other cellular locations, it is also important that we understand how PTMs affect the subcellular localization of CB components. In this review, we explore the current knowledge of PTMs on the activity of proteins known to enrich in CBs in an effort to highlight current progress as well as illuminate paths for future investigation.

  4. Toward an understanding of regulating Cajal body activity by protein modification.

    Science.gov (United States)

    Hebert, Michael D; Poole, Aaron R

    2016-10-07

    The biogenesis of small nuclear ribonucleoproteins (snRNPs), small Cajal body-specific RNPs (scaRNPs), small nucleolar RNPs (snoRNPs) and the telomerase RNP involves Cajal bodies (CBs). Although many components enriched in the CB contain post-translational modifications (PTMs), little is known about how these modifications impact individual protein function within the CB and, in concert with other modified factors, collectively regulate CB activity. Since all components of the CB also reside in other cellular locations, it is also important that we understand how PTMs affect the subcellular localization of CB components. In this review, we explore the current knowledge of PTMs on the activity of proteins known to enrich in CBs in an effort to highlight current progress as well as illuminate paths for future investigation.

  5. An Active Cooperation-Aware Spectrum Allocation Mechanism for Body Sensor Networks

    Directory of Open Access Journals (Sweden)

    Fu Jiang

    2015-01-01

    Full Text Available A cognitive radio-based spectrum allocation scheme using an active cooperative-aware mechanism is proposed in this paper. The scheme ensures that the primary user and secondary users cooperate actively for their own benefits. The primary user releases some spectrum resources to secondary users to actively stimulate them to actively join the cooperative transmission of the primary user, and secondary users help the primary user to relay data in return, as well as its self-data transmission at the same time. The Stackelberg game is used to evenly and jointly optimize the utilities of both the primary and secondary users. Simulation results show that the proposed active cooperation-aware mechanism could improve the body sensor network performance.

  6. An active cooperation-aware spectrum allocation mechanism for body sensor networks.

    Science.gov (United States)

    Jiang, Fu; Guo, Ying; Peng, Jun; Hu, Jiankun

    2015-01-28

    A cognitive radio-based spectrum allocation scheme using an active cooperative-aware mechanism is proposed in this paper. The scheme ensures that the primary user and secondary users cooperate actively for their own benefits. The primary user releases some spectrum resources to secondary users to actively stimulate them to actively join the cooperative transmission of the primary user, and secondary users help the primary user to relay data in return, as well as its self-data transmission at the same time. The Stackelberg game is used to evenly and jointly optimize the utilities of both the primary and secondary users. Simulation results show that the proposed active cooperation-aware mechanism could improve the body sensor network performance.

  7. Coevolution of telomerase activity and body mass in mammals: from mice to beavers.

    Science.gov (United States)

    Gorbunova, Vera; Seluanov, Andrei

    2009-01-01

    Telomerase is repressed in the majority of human somatic tissues. As a result human somatic cells undergo replicative senescence, which plays an important role in suppressing tumorigenesis, and at the same time contributes to the process of aging. Repression of somatic telomerase activity is not a universal phenomenon among mammals. Mice, for example, express telomerase in somatic tissues, and mouse cells are immortal when cultured at physiological oxygen concentration. What is the status of telomerase in other animals, beyond human and laboratory mouse, and why do some species evolve repression of telomerase activity while others do not? Here we discuss the data on telomere biology in various mammalian species, and a recent study of telomerase activity in a large collection of wild rodent species, which showed that telomerase activity coevolves with body mass, but not lifespan. Large rodents repress telomerase activity, while small rodents maintain high levels of telomerase activity in somatic cells. We discuss a model that large body mass presents an increased cancer risk, which drives the evolution of telomerase suppression and replicative senescence.

  8. Length of activity season drives geographic variation in body size of a widely distributed lizard

    OpenAIRE

    Horváthová, Terézia; Cooney, Christopher R.; Fitze, Patrick S; Oksanen, Tuula; Jelic, Dusan; Ghira, Ioan; Uller, Tobias; Jandzik, David

    2013-01-01

    Understanding the factors that drive geographic variation in life history is an important challenge in evolutionary ecology. Here, we analyze what predicts geographic variation in life-history traits of the common lizard, Zootoca vivipara, which has the globally largest distribution range of all terrestrial reptile species. Variation in body size was predicted by differences in the length of activity season, while we found no effects of environmental temperature per se. Females experiencing r...

  9. Status of bone mineral content and body composition in boys engaged in intensive physical activity

    Directory of Open Access Journals (Sweden)

    Madić Dejan

    2010-01-01

    Full Text Available Background/Aim. It is well known that physical activity has an anabolic effect on bone tissue. But there is a lack of information about the effect of intensive physical activity in childhood, particularly at the prepubertal stage. To examine the influence of training on body composition and bone mineral density we have studied a group of prepubertal soccer players as well as a group of inactive prepubertal boys at the starting phase of their peak bone mass acquisition. Methods. A total of 62 healthy prepubertal boys took part in this study. They were divided into two groups. The first one consisted of 32 soccer players (aged 10.7 ± 0.5 years, who had been playing football for at least 1 year (10-15 h per week. The second group a control group 30 boys (aged 11.2 ± 0.7 years doing 1.5 h per week physical activity at school. Body composition was assessed by a Body Fat Analyzer 'BES 200 Z'. Bone mineral density measurements of the left and the right calcaneus were done by using ultrasound densitometer 'Sahara' (Hologic, Inc., MA, USA. Results. There were significant differences between soccer players and the control group in fat mass (p = 0.01. Besides, a significant difference was determined between the group of athletes and the control group in bone mineral density of both calcaneal bones (p = 0.01. Conclusion. The results of this study confirm the significant effects of physical activity on reducing body mass and increasing bone density. Considering that football training can be very easily implemented in the broader population of children and young people, which does not apply to many other sports, it should be used more in the prevention of obesity and osteoporosis.

  10. Role of physical activity and sleep duration in growth and body composition of preschool-aged children

    Science.gov (United States)

    The impact of physical activity patterns and sleep duration on growth and body composition of preschool-aged children remains unresolved. Aims were (1) to delineate cross-sectional associations among physical activity components, sleep, total energy expenditure (TEE), and body size and composition; ...

  11. Regression analysis between body and head measurements of Chinese alligators (Alligator sinensis in the captive population

    Directory of Open Access Journals (Sweden)

    Wu, X. B.

    2006-06-01

    Full Text Available Four body-size and fourteen head-size measurements were taken from each Chinese alligator (Alligator sinensis according to the measurements adapted from Verdade. Regression equations between body-size and head-size variables were presented to predict body size from head dimension. The coefficients of determination of captive animals concerning body- and head-size variables can be considered extremely high, which means most of the head-size variables studied can be useful for predicting body length. The result of multivariate allometric analysis indicated that the head elongates as in most other species of crocodilians. The allometric coefficients of snout length (SL and lower ramus (LM were greater than those of other variables of head, which was considered to be possibly correlated to fights and prey. On the contrary, allometric coefficients for the variables of obita (OW, OL and postorbital cranial roof (LCR, were lower than those of other variables.

  12. Effects of a water aerobics program on the body composition of active middle-aged women

    OpenAIRE

    Manzano, Juan José; Clemente, Christian; Grager, Asunción; Olcina, Guillermo

    2011-01-01

    Objective: Describe and analyze changes in body composition of middle-aged women after participating in a water aerobics physical activity program and a subsequent detraining period. Materials and Methods: The group analyzed consisted of 17 women from Arroyo de San Serván (Badajoz), who were physically active (had participated in fitness gymnastics programs one to three sessions per week for the past three months), with an average age of 53.6 ± 9.1 years. The program was comprised of sixty mi...

  13. Mathematical modeling of spinning elastic bodies for modal analysis.

    Science.gov (United States)

    Likins, P. W.; Barbera, F. J.; Baddeley, V.

    1973-01-01

    The problem of modal analysis of an elastic appendage on a rotating base is examined to establish the relative advantages of various mathematical models of elastic structures and to extract general inferences concerning the magnitude and character of the influence of spin on the natural frequencies and mode shapes of rotating structures. In realization of the first objective, it is concluded that except for a small class of very special cases the elastic continuum model is devoid of useful results, while for constant nominal spin rate the distributed-mass finite-element model is quite generally tractable, since in the latter case the governing equations are always linear, constant-coefficient, ordinary differential equations. Although with both of these alternatives the details of the formulation generally obscure the essence of the problem and permit very little engineering insight to be gained without extensive computation, this difficulty is not encountered when dealing with simple concentrated mass models.

  14. The Dynamic Response Analysis of Auto Body Sheets to Node Loads

    Directory of Open Access Journals (Sweden)

    Luo Yun

    2014-01-01

    Full Text Available The 3D vehicle body model was built using UG NX6.0, then it was imported into the Workbench of Finite Elment Analyis Software ANSYS V12.1. In the Workbench, the modal analysis and harmonic response analysis of auto body sheets with 4 kinds of node load environment are implemented. Meanwhile the harmonic response analysis of engine’s single sine vibration is obtained in stimulation processing based on the modal calculation. Then the rule of influence on the auto body sheets to node load environment was explored further. Node load environment increased the resonance amplitude of harmonic response analysis. What’s more, the resonance amplitude increased as the increasing of node loads, which would increase the probability of vehicle structure failure.

  15. Increased neural activity of a mushroom body neuron subtype in the brains of forager honeybees.

    Directory of Open Access Journals (Sweden)

    Taketoshi Kiya

    Full Text Available Honeybees organize a sophisticated society, and the workers transmit information about the location of food sources using a symbolic dance, known as 'dance communication'. Recent studies indicate that workers integrate sensory information during foraging flight for dance communication. The neural mechanisms that account for this remarkable ability are, however, unknown. In the present study, we established a novel method to visualize neural activity in the honeybee brain using a novel immediate early gene, kakusei, as a marker of neural activity. The kakusei transcript was localized in the nuclei of brain neurons and did not encode an open reading frame, suggesting that it functions as a non-coding nuclear RNA. Using this method, we show that neural activity of a mushroom body neuron subtype, the small-type Kenyon cells, is prominently increased in the brains of dancer and forager honeybees. In contrast, the neural activity of the two mushroom body neuron subtypes, the small-and large-type Kenyon cells, is increased in the brains of re-orienting workers, which memorize their hive location during re-orienting flights. These findings demonstrate that the small-type Kenyon cell-preferential activity is associated with foraging behavior, suggesting its involvement in information integration during foraging flight, which is an essential basis for dance communication.

  16. To use or not to use torpor? Activity and body temperature as predictors

    Science.gov (United States)

    Christian, Nereda; Geiser, Fritz

    2007-06-01

    When food is limited and/or environmental conditions are unfavourable, many mammals reduce activity and use torpor to save energy. Nevertheless, reliable predictors for torpor occurrence, especially in the wild, are currently not available. Interrelations between torpor use and other energy conserving strategies are also poorly understood. We tested the hypothesis that reductions in normothermic body temperature ( T b) and the period of activity before torpor events could be used as predictors for torpor occurrence in sugar gliders, Petaurus breviceps (body mass, ˜125 g), known to display daily torpor in the wild. Occurrence of torpor was preceded by significant (˜10-25%) reductions of the duration of the activity phase. Moreover, the normothermic resting T b fell by an average of 1.2°C over 3 days before a torpor event, relative to individuals that did not display torpor. Our new findings suggest that before entering torpor, sugar gliders, which appear to use torpor as an emergency measure rather than a routine energy saving strategy, systematically reduce activity times and normothermic resting T bs to lower energy expenditure and perhaps to avoid employing torpor. Thus, reduced activity and normothermic T b may provide a predictive tool for the occurrence of daily torpor in the wild.

  17. Body weight satisfaction and disordered eating among youth who are active in sport in Singapore

    Directory of Open Access Journals (Sweden)

    Michael Chia

    2015-04-01

    Full Text Available Purpose : The research examined the relationship between body weight satisfaction and disordered eating among youth who are active in sport in Singapore. Method : 137 youths (82 boys and 55 girls; age 12-13 enrolled in school sport completed two self-report questionnaires- SCOFF for disordered eating and body weight satisfaction- on two separate occasions that were six months apart (T1 vs. T2. Results : Body mass index for age classifications revealed that 5.1% were severely underweight; 1.5% underweight; 88.3% acceptable weight; 4.4% overweight and 0.7% were severely overweight. Conclusions : (i the prevalence of disordered eating was 46% at baseline measurement and this remained stable at 45.3% six months later; (ii there was no sex difference for disordered eating on the two measurement occasions (T1 vs. T2, p>0.05; (iii the prevalence of youths unsure of their bodyweight satisfaction was 26.6-21.2% which compared to 88.3% adjudged to be of healthy weight; across T1 and T2, more male subjects wanted to gain bodyweight while more female subjects wanted to lose bodyweight; and (iv subjects who were dissatisfied with their bodyweight had significantly greater odds of being at risk for developing DE. Holistic education programmes based upon body image and nutrition, are recommended.

  18. A 10-Month Physical Activity Intervention Improves Body Composition in Young Black Boys

    Directory of Open Access Journals (Sweden)

    Cheryl A. Howe

    2011-01-01

    Full Text Available Objective. To determine if a 10-month after-school physical activity (PA intervention could prevent deleterious changes in body composition and cardiovascular (CV fitness in young black boys. Methods. Following baseline measures, 106 boys (8–12 yrs were randomized to either a control group or an intervention group, further divided into attenders (ATT and nonattenders (NATT, participating in ≥60% or <60% of the intervention, respectively. The daily intervention consisted of skills development (25 min, vigorous PA (VPA, 35 min, and strengthening/stretching (20 min components. Body composition was measured by dual-energy X-ray absorptiometry. Results. Following the intervention, the ATT exhibited an increase in moderate-to-vigorous PA and a significant reduction in BMI, fat mass, and %BF compared to the control group. A significant association among the intervention energy expenditure and changes in body composition and CV fitness was observed only in the ATT group. Conclusion. An after-school PA program of sufficient length and intensity can promote healthy changes in body composition and fitness levels in black boys who attend at least 3 days/week.

  19. Active numerical model of human body for reconstruction of falls from height.

    Science.gov (United States)

    Milanowicz, Marcin; Kędzior, Krzysztof

    2017-01-01

    Falls from height constitute the largest group of incidents out of approximately 90,000 occupational accidents occurring each year in Poland. Reconstruction of the exact course of a fall from height is generally difficult due to lack of sufficient information from the accident scene. This usually results in several contradictory versions of an incident and impedes, for example, determination of the liability in a judicial process. In similar situations, in many areas of human activity, researchers apply numerical simulation. They use it to model physical phenomena to reconstruct their real course over time; e.g. numerical human body models are frequently used for investigation and reconstruction of road accidents. However, they are validated in terms of specific road traffic accidents and are considerably limited when applied to the reconstruction of other types of accidents. The objective of the study was to develop an active numerical human body model to be used for reconstruction of accidents associated with falling from height. Development of the model involved extension and adaptation of the existing Pedestrian human body model (available in the MADYMO package database) for the purposes of reconstruction of falls from height by taking into account the human reaction to the loss of balance. The model was developed by using the results of experimental tests of the initial phase of the fall from height. The active numerical human body model covering 28 sets of initial conditions related to various human reactions to the loss of balance was developed. The application of the model was illustrated by using it to reconstruct a real fall from height. From among the 28 sets of initial conditions, those whose application made it possible to reconstruct the most probable version of the incident was selected. The selection was based on comparison of the results of the reconstruction with information contained in the accident report. Results in the form of estimated

  20. Dose evaluation based on 24Na activity in the human body at the JCO criticality accident in Tokai-mura.

    Science.gov (United States)

    Momose, T; Tsujimura, N; Tasaki, T; Kanai, K; Kurihara, O; Hayashi, N; Shinohara, K

    2001-09-01

    24Na in the human body, activated by neutrons emitted at the JCO criticality accident, was observed for 62 subjects, where 148 subjects were measured by the whole body counter of JNC Tokai Works. The 148 subjects, including JCO employees and the contractors, residents neighboring the site and emergency service officers, were measured by the whole-body counter. The neutron-energy spectrum around the facility was calculated using neutron transport codes (ANISN and MCNP), and the relation between an amount of activated sodium in human body and neutron dose was evaluated from the calculated neutron energy spectrum and theoretical neutron capture probability by the human body. The maximum 24Na activity in the body was 7.7 kBq (83 Bq(24Na)/g(23Na)) and the relevant effective dose equivalent was 47 mSv.

  1. The “Iron Screen”: Progressive Development of an Interpretative Analysis of Body Iron Status

    OpenAIRE

    Beck, J. Robert; Turpin, Edward H.; Rawnsley, Howard M

    1982-01-01

    The Iron Screen, a sequential Bayesian decision-making model for the assessment of body iron stores in man, is a special example of the blending of computer support, decision analysis, and multivariate statistical techniques in medicine. This model, originally developed and tested in patients with chronic diseases and a question of iron deficiency anemia, has recently been broadened to include all pateints for whom body iron stores must be determined. In this report we describe operational ex...

  2. Time-Domain Analysis of a Wire Antenna Near Arbitrarily Shaped Conductor Bodies

    Institute of Scientific and Technical Information of China (English)

    Zheng; Li-Zhi; Xiao; Bo-xun; 等

    2003-01-01

    A time domain electrical field integral equation (TDEFIE) is formulated for the problem of a thin wire antenna in the presence of conductor bodies, and this equation is solved by the method in time marching algorithm. The analysis is valid for any arbitrarily shaped, oriented and positioned wire antennas relative to arbitrarily shaped conductor bodies. Current at the excited point, input admittance and radiation pattern are given and agree with the results computed by the method in frequency domain.

  3. Time-Domain Analysis of a Wire Antenna Near Arbitrarily Shaped Conductor Bodies

    Institute of Scientific and Technical Information of China (English)

    Zheng Li-zhi; Xiao Bo-xur; Zhu Guo-qiang; Yang Zi-jie

    2003-01-01

    A time domain electrical field integral equation (TDEFIE) is formulated for the problem of a thin wire antenna in the presence of conductor bodies, and this equation is solved by the method of time marching algorithm. The analysis is valid for any arbitrarily shaped, oriented and positioned wire antennas relative to arbitrarily shaped conductor bodies. Current at the excited point, input admittance and radiation pattern are given and agree with the results computed by the method in frequency domain.

  4. Balance Maintenance in the Upright Body Position: Analysis of Autocorrelation

    Directory of Open Access Journals (Sweden)

    Stodolka¹ Jacek

    2016-04-01

    Full Text Available The present research aimed to analyze values of the autocorrelation function measured for different time values of ground reaction forces during stable upright standing. It was hypothesized that if recording of force in time depended on the quality and way of regulating force by the central nervous system (as a regulator, then the application of autocorrelation for time series in the analysis of force changes in time function would allow to determine regulator properties and its functioning. The study was performed on 82 subjects (students, athletes, senior and junior soccer players and subjects who suffered from lower limb injuries. The research was conducted with the use of two Kistler force plates and was based on measurements of ground reaction forces taken during a 15 s period of standing upright while relaxed. The results of the autocorrelation function were statistically analyzed. The research revealed a significant correlation between a derivative extreme and velocity of reaching the extreme by the autocorrelation function, described as gradient strength. Low correlation values (all statistically significant were observed between time of the autocorrelation curve passing through 0 axis and time of reaching the first peak by the said function. Parameters computed on the basis of the autocorrelation function are a reliable means to evaluate the process of flow of stimuli in the nervous system. Significant correlations observed between the parameters of the autocorrelation function indicate that individual parameters provide similar properties of the central nervous system.

  5. Three-dimensional morphological analysis method for geologic bodies and its parallel implementation

    Science.gov (United States)

    Mao, Xiancheng; Zhang, Bin; Deng, Hao; Zou, Yanhong; Chen, Jin

    2016-11-01

    It has been found that the spatial locations and distributions of orebodies, especially for certain hydrothermal mineral deposits, are closely related to the shape of intrusive geologic bodies. For complex and large-scale geologic bodies, however, it is challenging to achieve rigorous and quantitative morphological analysis by standard geological surface reconstruction and trend-surface analysis methods. This paper presents a novel, quantitative morphological analysis method for general geologic bodies of closed 2-manifold surface based on mathematical morphology. Through the processes of morphological filtering, set operations and three-dimensional Euclidean distance transform (3D-EDT), the global trend shape, local convex and concave zones as well as degree of surface undulation of a geologic body are extracted respectively. All of the three analysis phases are speeded up via parallel algorithms implemented by using the message passing interface (MPI) standard. The proposed method is tested with a case study of the Xinwuli intrusion with complex shape in Fenghuangshan deposit of the Tongling district, China. The results demonstrate that the method is an effective and efficient way to achieve quantitative morphological analysis, thereby decreasing the time necessary to find the association between morphological parameters of geologic bodies and mineralization.

  6. From body art to anticancer activities: perspectives on medicinal properties of henna.

    Science.gov (United States)

    Pradhan, Rohan; Dandawate, Prasad; Vyas, Alok; Padhye, Subhash; Biersack, Bernhard; Schobert, Rainer; Ahmad, Aamir; Sarkar, Fazlul H

    2012-12-01

    Nature has been a rich source of therapeutic agents for thousands of years and an impressive number of modern drugs have been isolated from natural sources based on the uses of these plants in traditional medicine. Henna is one such plant commonly known as Persian Henna or Lawsonia inermis, a bushy, flowering tree, commonly found in Australia, Asia and along the Mediterranean coasts of Africa. Paste made from the leaves of Henna plant has been used since the Bronze Age to dye skin, hairs and fingernails especially at the times of festivals. In recent times henna paste has been used for body art paintings and designs in western countries. Despite such widespread use in dyeing and body art painting, Henna extracts and constituents possess numerous biological activities including antioxidant, anti-inflammatory, antibacterial and anticancer activities. The active coloring and biologically active principle of Henna is found to be Lawsone (2- hydroxy-1, 4-naphthoquinone) which can serve as a starting building block for synthesizing large number of therapeutically useful compounds including Atovaquone, Lapachol and Dichloroallyl lawsone which have been shown to possess potent anticancer activities. Some other analogs of Lawsone have been found to exhibit other beneficial biological properties such as antioxidant, anti-inflammatory, antitubercular and antimalarial. The ability of Lawsone to undergo the redox cycling and chelation of trace metal ions has been thought to be partially responsible for some of its biological activities. Despite such diverse biological properties and potent anticancer activities the compound has remained largely unexplored and hence in the present review we have summarized the chemistry and biological activities of Lawsone along with its analogs and metal complexes.

  7. Early aqueous activity on the ordinary and carbonaceous chondrite parent bodies recorded by fayalite.

    Science.gov (United States)

    Doyle, Patricia M; Jogo, Kaori; Nagashima, Kazuhide; Krot, Alexander N; Wakita, Shigeru; Ciesla, Fred J; Hutcheon, Ian D

    2015-06-23

    Chronology of aqueous activity on chondrite parent bodies constrains their accretion times and thermal histories. Radiometric (53)Mn-(53)Cr dating has been successfully applied to aqueously formed carbonates in CM carbonaceous chondrites. Owing to the absence of carbonates in ordinary (H, L and LL), and CV and CO carbonaceous chondrites, and the lack of proper standards, there are no reliable ages of aqueous activity on their parent bodies. Here we report the first (53)Mn-(53)Cr ages of aqueously formed fayalite in the L3 chondrite Elephant Moraine 90161 as Myr after calcium-aluminium-rich inclusions (CAIs), the oldest Solar System solids. In addition, measurements using our synthesized fayalite standard show that fayalite in the CV3 chondrite Asuka 881317 and CO3-like chondrite MacAlpine Hills 88107 formed and Myr after CAIs, respectively. Thermal modelling, combined with the inferred conditions (temperature and water/rock ratio) and (53)Mn-(53)Cr ages of aqueous alteration, suggests accretion of the L, CV and CO parent bodies ∼1.8-2.5 Myr after CAIs.

  8. Anaphylaxis Imaging: Non-Invasive Measurement of Surface Body Temperature and Physical Activity in Small Animals.

    Directory of Open Access Journals (Sweden)

    Krisztina Manzano-Szalai

    Full Text Available In highly sensitized patients, the encounter with a specific allergen from food, insect stings or medications may rapidly induce systemic anaphylaxis with potentially lethal symptoms. Countless animal models of anaphylaxis, most often in BALB/c mice, were established to understand the pathophysiology and to prove the safety of different treatments. The most common symptoms during anaphylactic shock are drop of body temperature and reduced physical activity. To refine, improve and objectify the currently applied manual monitoring methods, we developed an imaging method for the automated, non-invasive measurement of the whole-body surface temperature and, at the same time, of the horizontal and vertical movement activity of small animals. We tested the anaphylaxis imaging in three in vivo allergy mouse models for i milk allergy, ii peanut allergy and iii egg allergy. These proof-of-principle experiments suggest that the imaging technology represents a reliable non-invasive method for the objective monitoring of small animals during anaphylaxis over time. We propose that the method will be useful for monitoring diseases associated with both, changes in body temperature and in physical behaviour.

  9. Physical activity and bone health in schoolchildren: the mediating role of fitness and body fat.

    Directory of Open Access Journals (Sweden)

    Ana Torres-Costoso

    Full Text Available The relationship between physical activity (PA and bone health is well known, although the role of percent body fat (%BF and fitness as confounders or mediators in this relationship remains uncertain.To examine whether the association between PA and bone mineral content (BMC is mediated by %BF and cardiorespiratory fitness (CRF.In this cross sectional study, BMC, total %BF (by DXA, vigorous PA (VPA, CRF, age and height were measured in 132 schoolchildren (62 boys, aged 8-11 years. ANCOVA was used to test differences in BMC by %BF, CRF and VPA, controlling for different sets of confounders. Simple mediation analyses and serial multiple mediation analyses were fitted to examine whether the relationship between PA and BMC is mediated by %BF and fitness.Children with high %BF had higher total body BMC than their peers after controlling for all sets of confounders. Children with good CRF or VPA had significantly less total body BMC after controlling for age and sex but in children with good CRF this inverse relation disappeared after adjusting by %BF. %BF and CRF both act as a full mediator in the association between VPA and BMC, after inclusion of the potential confounders in the models.Fitness and %BF seem to have a mediator role on the relationship between physical activity and bone mass.

  10. Assessment of physical activity of the human body considering the thermodynamic system.

    Science.gov (United States)

    Hochstein, Stefan; Rauschenberger, Philipp; Weigand, Bernhard; Siebert, Tobias; Schmitt, Syn; Schlicht, Wolfgang; Převorovská, Světlana; Maršík, František

    2016-01-01

    Correctly dosed physical activity is the basis of a vital and healthy life, but the measurement of physical activity is certainly rather empirical resulting in limited individual and custom activity recommendations. Certainly, very accurate three-dimensional models of the cardiovascular system exist, however, requiring the numeric solution of the Navier-Stokes equations of the flow in blood vessels. These models are suitable for the research of cardiac diseases, but computationally very expensive. Direct measurements are expensive and often not applicable outside laboratories. This paper offers a new approach to assess physical activity using thermodynamical systems and its leading quantity of entropy production which is a compromise between computation time and precise prediction of pressure, volume, and flow variables in blood vessels. Based on a simplified (one-dimensional) model of the cardiovascular system of the human body, we develop and evaluate a setup calculating entropy production of the heart to determine the intensity of human physical activity in a more precise way than previous parameters, e.g. frequently used energy considerations. The knowledge resulting from the precise real-time physical activity provides the basis for an intelligent human-technology interaction allowing to steadily adjust the degree of physical activity according to the actual individual performance level and thus to improve training and activity recommendations.

  11. Food reward in active compared to inactive men: Roles for gastric emptying and body fat.

    Science.gov (United States)

    Horner, Katy M; Finlayson, Graham; Byrne, Nuala M; King, Neil A

    2016-06-01

    Habitual exercise could contribute to weight management by altering processes of food reward via the gut-brain axis. We investigated hedonic processes of food reward in active and inactive men and characterised relationships with gastric emptying and body fat. Forty-four men (active: n=22; inactive: n=22, BMI range 21-36kg/m(2); percent fat mass range 9-42%) were studied. Participants were provided with a standardised fixed breakfast and an ad libitum lunch meal 5h later. Explicit liking, implicit wanting and preference among high-fat, low-fat, sweet and savoury food items were assessed immediately post-breakfast (fed state) and again pre-lunch (hungry state) using the Leeds Food Preference Questionnaire. Gastric emptying was assessed by (13)C-octanoic acid breath test. Active individuals exhibited a lower liking for foods overall and a greater implicit wanting for low-fat savoury foods in the fed state, compared to inactive men. Differences in the fed state remained significant after adjusting for percent fat mass. Active men also had a greater increase in liking for savoury foods in the interval between breakfast and lunch. Faster gastric emptying was associated with liking for savoury foods and with an increase in liking for savoury foods in the postprandial interval. In contrast, greater implicit wanting for high-fat foods was associated with slower gastric emptying. These associations were independent of each other, activity status and body fat. In conclusion, active and inactive men differ in processes of food reward. The rate of gastric emptying may play a role in the association between physical activity status and food reward, via the gut-brain axis.

  12. Body size, physical activity and risk of breast cancer - a case control study in Jangsu Province of China.

    Science.gov (United States)

    Gao, Chang-Ming; Tajima, Kazuo; Ding, Jian-Hua; Tang, Jin-Hai; Wu, Jian-Zhong; Li, Su-Ping; Cao, Hai-Xia; Liu, Yan-Ting; Su, Ping; Qian, Yun; Chang, Jun; Takezaki, Toshiro

    2009-01-01

    To evaluate the relationship between body size, physical activity and risk of breast cancer, we conducted a case-control study with 669 cases and 682 population-based controls in Jiangsu Province of China. A structured questionnaire was used to elicit detailed information. All subjects completed an in-person interview. The body mass index (BMI) was calculated based on weights and heights. Unconditional logistic regression analysis was performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) as measures of risk for breast cancer. Current height, weight and weight at around age 20 years were significantly positively correlated with risk of breast cancer. Obese women (current BMI > or = 25 kg/m2) were at significantly increased risk for developing breast cancer (adjusted OR= 1.35, 95%CI: 1.01-1.81), but, between BMI at around age 20 years and risk of breast cancer showed an inverse association (P for trend = 0.001). Women who had middle physical force work were at significantly lowered OR (0.62, 95%CI: 0.41-0.93) compared with women of headwork. Using women who standing or ambulation per day less than one hour as the reference, women who standing or ambulation more than one hour had a decreased risk of breast cancer. Using women who slept less than 5 hours per day as the reference, the women who slept 5-8 hours were at significantly decreased risk of breast cancer. Women who had habit of recreational physical activity were at significantly decreased risk (adjusted OR= 0.68, 95%CI: 0.53-0.88), with an inverse association between the exercise times per week and risk of breast cancer (P for trend = 0.025). These findings support that breast cancer risk is associated with body size, and that moderate occupational and recreational physical activity has protective effects on breast cancer.

  13. Analysis of measured data of human body based on error correcting frequency

    Science.gov (United States)

    Jin, Aiyan; Peipei, Gao; Shang, Xiaomei

    2014-04-01

    Anthropometry is to measure all parts of human body surface, and the measured data is the basis of analysis and study of the human body, establishment and modification of garment size and formulation and implementation of online clothing store. In this paper, several groups of the measured data are gained, and analysis of data error is gotten by analyzing the error frequency and using analysis of variance method in mathematical statistics method. Determination of the measured data accuracy and the difficulty of measured parts of human body, further studies of the causes of data errors, and summarization of the key points to minimize errors possibly are also mentioned in the paper. This paper analyses the measured data based on error frequency, and in a way , it provides certain reference elements to promote the garment industry development.

  14. Medical application of in vivo neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Zanzi, I.; Aloia, J.F.

    1978-01-01

    The clinical usefulness of total body neutron activation analysis (TBNAA) was clearly established at an IAEA panel meeting in Vienna in 1972. It is best demonstrated by the studies involving the measurement of total-body calcium. This measurement provides data useful for the diagnosis and management of metabolic bone disorders. It should be emphasized, however, that while most of the applications to date have involved calcium and phosphorus, the measurement of sodium, chlorine and nitrogen also appear to be useful clinically. Total-body calcium measurements utilizing TBNAA have been used in studies of osteoporosis to establish absolute and relative deficits of calcium in patients with this disease in comparison to a normal contrast population. Changes in total-body calcium (skeletal mass) have also been useful for quantitating the efficacy of various therapies in osteoporosis. Serial measurements over periods of years provide long-term balance data by direct measurement with a higher precision (+- 2%) than is possible by the use of any other technique. In the renal osteodystrophy observed in patients with renal failure, disorders of both calcium and phosphorus, as well as electrolyte disturbances, have been studied. The measure of total-body levels of these elements gives the clinician useful data upon which to design dialysis therapy. The measurement of bone changes in endocrine dysfunction has been studied, particularly in patients with thyroid and parathyroid disorders. In parathyroidectomy, the measurement of total-body calcium, post-operatively, can indicate the degree of bone resorption. Skeletal metabolism and body composition in acromegaly and Cushing's disease have also been investigated by TBNAA. Levels of cadmium in liver and kidney have also been measured in-vivo by prompt-gamma neutron activation and associated with hypertension, emphysema and cigarette smoking.

  15. ASYMMETRIC VORTICES FLOW OVER SLENDER BODY AND ITS ACTIVE CONTROL AT HIGH ANGLE OF ATTACK

    Institute of Scientific and Technical Information of China (English)

    DENG Xueying; WANG Yankui

    2004-01-01

    The studies of asymmetric vortices flow over slender body and its active control at high angles of attack have significant importance for both academic field and engineering area. This paper attempts to provide an update state of art to the investigations on the fields of forebody asymmetric vortices. This review emphasizes the correlation between micro-perturbation on the model nose and its response and evolution behaviors of the asymmetric vortices. The critical issues are discussed,which include the formation and evolution mechanism of asymmetric multi-vortices; main behaviors of asymmetric vortices flow including its deterministic feature and vortices flow structure; the evolution and development of asymmetric vortices under the perturbation on the model nose; forebody vortex active control especially discussed micro-perturbation active control concept and technique in more detail. However present understanding in this area is still very limited and this paper tries to identify the key unknown problems in the concluding remarks.

  16. Active video gaming improves body coordination in survivors of childhood brain tumours

    DEFF Research Database (Denmark)

    Sabel, M.; Sjölund, A.; Broeren, J.

    2016-01-01

    Purpose: We investigated whether active video gaming (AVG) could bring about regular, enjoyable, physical exercise in children treated for brain tumours, what level of physical activity could be reached and if the children’s physical functioning improved. Methods: Thirteen children, aged 7–17 years...... compared to their healthy peers. Active video gaming (AVG), supported by Internet coaching, is a feasible home-based intervention in children treated for brain tumours, promoting enjoyable, regular physical exercise of moderate intensity. In this pilot study, AVG with Nintendo Wii improved Body......-blinded assessments of physical functioning were done, using the Bruininks–Osteretsky Test of Motor Performance, second edition, evaluating participants before and after the intervention period, as well as comparing the randomisation groups after the first period. Results: All patients completed the study. AVG...

  17. A New Approach and Analysis of Modeling the Human Body in RFID-Enabled Body-Centric Wireless Systems

    Directory of Open Access Journals (Sweden)

    Karoliina Koski

    2014-01-01

    Full Text Available Body-centric wireless systems demand wearable sensor and tag antennas that have robust impedance matching and provide enough gain for a reliable wireless communication link. In this paper, we discuss a novel and practical technique for the modeling of the human body in UHF RFID body-centric wireless systems. What makes this technique different is that we base the human model on measured far-field response from a reference tag attached to the human body. Hereby, the human body model accounts for the encountered human body effects on the tag performance. The on-body measurements are fast, which allows establishing a catalog of human body models for different tag locations and human subjects. Such catalog would provide a ready simulation model for a wide range of wireless body-centric applications in order to initiate a functional design. Our results demonstrate that the suggested modeling technique can be used in the design and optimization of wearable antennas for different real-case body-centric scenarios.

  18. Association between body weight, physical activity and food choices among metropolitan transit workers

    Directory of Open Access Journals (Sweden)

    Hannan Peter J

    2007-11-01

    Full Text Available Abstract Background Associations between body weight, physical activity and dietary intake among a population of metropolitan transit workers are described. Methods Data were collected during October through December, 2005, as part of the baseline measures for a worksite weight gain prevention intervention in four metro transit bus garages. All garage employees were invited to complete behavioral surveys that assessed food choices and physical activity, and weight and height were directly measured. Seventy-eight percent (N = 1092 of all employees participated. Results The prevalence of obesity (BMI >= 30 kg/m2 was 56%. Over half of the transit workers reported consuming fruit (55% and vegetables (59% ≥ 3/week. Reported fast food restaurant frequency was low (13% visited ≥ 3/week. Drivers reported high levels of physical activity (eg. walking 93 minutes/day. However, an objective measure of physical activity measured only 16 minutes moderate/vigorous per day. Compared to other drivers, obese drivers reported significantly less vigorous physical activity, more time sitting, and more time watching television. Healthy eating, physical activity and weight management were perceived to be difficult at the worksite, particularly among obese transit workers, and perceived social support for these behaviors was modest. However, most workers perceived weight management and increased physical activity to be personally important for their health. Conclusion Although transit workers' self-report of fruit and vegetable intake, and physical activity was high, perceived access to physical activity and healthful eating opportunities at the worksite was low. Obese workers were significantly less physically active and were more likely to report work environmental barriers to physical activity.

  19. Analysis of body posture in children with mild to moderate asthma.

    Science.gov (United States)

    Belli, Juliana Fernanda Canhadas; Chaves, Thaís Cristina; de Oliveira, Anamaria Siriani; Grossi, Débora Bevilaqua

    2009-10-01

    The mechanical alterations related to the excessive use of accessory respiratory muscles and the mouth breathing observed in children with asthma may lead to the development of alterations in head posture, shoulders, thoracic region and, consequently, in alterations of body posture. The purpose of this study was to assess body posture changes of children with asthma compared to a non-asthmatic control group matched for gender, age, weight, and height. Thirty children with asthma and 30 non-asthmatic children aged 7 to 12 years were enrolled in this study. Digital photographic records were obtained for analysis of the body posture of the children by computed photogrammetry. The intraclass correlation coefficient and Student's t test (p postural alterations compared to non-asthmatic controls since the only angle for which there was a significant difference between groups showed weak reproducibility. The findings of this study do not support the notion that children with asthma present alterations in body posture.

  20. Validation of bioelectrical-impedance analysis as a measurement of change in body composition in obesity

    Energy Technology Data Exchange (ETDEWEB)

    Kushner, R.F.; Kunigk, A.; Alspaugh, M.; Andronis, P.T.; Leitch, C.A.; Schoeller, D.A. (Univ. of Chicago, IL (USA))

    1990-08-01

    The bioelectrical-impedance-analysis (BIA) method accurately measures body composition in weight-stable subjects. This study validates the use of BIA to measure change in body composition. Twelve obese females underwent weight loss at a mean rate of 1.16 kg/wk. Body composition was measured by deuterium oxide dilution (D2O), BIA, and skinfold anthropometry (SFA) at baseline and at 5% decrements in weight. Highly significant correlations were obtained between D2O and BIA (r = 0.971) and between D2O and SFA (r = 0.932). Overall, BIA predicted change in fat-free mass with greater accuracy (to 0.4 kg) and precision (+/- 1.28 kg) than did anthropometry (to 0.8 kg and +/- 2.58 kg, respectively). We conclude that BIA is a useful clinical method for measuring change in body composition.

  1. Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature.

    Directory of Open Access Journals (Sweden)

    Jasmine Sethi

    Full Text Available Histamine regulates arousal, circadian rhythms, and thermoregulation. Activation of H3 histamine receptors expressed by preoptic GABAergic neurons results in a decrease of their firing rate and hyperthermia. Here we report that an increase in the A-type K⁺ current in preoptic GABAergic neurons in response to activation of H3 histamine receptors results in decreased firing rate and hyperthermia in mice. The Kv4.2 subunit is required for these actions in spite of the fact that Kv4.2⁻/⁻ preoptic GABAergic neurons display A-type currents and firing characteristics similar to those of wild-type neurons. This electrical remodeling is achieved by robust upregulation of the expression of the Kv4.1 subunit and of a delayed rectifier current. Dynamic clamp experiments indicate that enhancement of the A-type current by a similar amount to that induced by histamine is sufficient to mimic its robust effect on firing rates. These data indicate a central role played by the Kv4.2 subunit in histamine regulation of body temperature and its interaction with pERK1/2 downstream of the H3 receptor. We also reveal that this pathway provides a mechanism for selective modulation of body temperature at the beginning of the active phase of the circadian cycle.

  2. Role of estrogen receptor binding and transcriptional activity in the stimulation of hyperestrogenism and nuclear bodies.

    Science.gov (United States)

    Clark, J H; Hardin, J W; Padykula, H A; Cardasis, C A

    1978-06-01

    The effects of estradiol and nafoxidine on nuclear estrogen receptor binding, RNA polymerase activities, and uterine ultrastructure were studied. Animals were either injected with estradiol, implanted with estradiol/paraffin pellets, or injected with nafoxidine. Animals treated with nafoxidine or estradiol implants showed sustained long-term nuclear retention of estrogen receptor and increased nuclear RNA polymerase activities for up to 72 hr. A single injection of estradiol caused initial increases in these variables which returned to control levels by 24 hr after hormone treatment. Uterine tissue was examined by light and electron microscopy 72 hr after hormone treatments. Uteri from eith estradiol-implanted or nafoxidine-treated animals showed markedly increased hypertrophy of the luminal epithelial cells. Nuclei in sections of the uteri of these hyperestrogenized animals displayed a large number and wide array of nuclear bodies composed of a filamentous capsule and granular cores. We conclude that hyperestrogenization, a condition that eventually results in abnormal cell growth, is correlated with increased and sustained nuclear binding of the estrogen receptor, increased and sustained RNA polymerase activity, and the appearance of nuclear bodies.

  3. Body Image and Nutritional Status Are Associated with Physical Activity in Men and Women: The ELSA-Brasil Study.

    Science.gov (United States)

    Coelho, Carolina G; Giatti, Luana; Molina, Maria D C B; Nunes, Maria A A; Barreto, Sandhi M

    2015-05-29

    The association of body image dissatisfaction and obesity with physical activity is likely to differ according to gender. To investigate this hypothesis, we conducted a cross-sectional study among the ELSA-Brasil cohort members aged 34-65 years (n=13,286). The body image dissatisfaction was present even among normal weight individuals of both sexes and was associated with lesser chances of practicing moderate physical activity in women and intense physical activity in men. Men and women with central obesity were less prone to practice physical activity of high or moderate intensity. Overweight and obese men were more likely to report vigorous physical activity while obese women were less likely to report this level of physical activity. Body images as well as nutritional status are related to physical activity in both sexes, but the association with physical activity differs by gender.

  4. Body Clock

    Institute of Scientific and Technical Information of China (English)

    刘洪毓

    2000-01-01

    Body clocks” are biological methods of controling body activities.Every living thing has one. In humans, a body clock controls normal periods of sleeping and waking. It controls the time swhen you are most likely to feel pain.Eating, sleeping and exercising at about the same time each day will help keep body activities normal. But changes in your life, a new job, for example, destroy the balance and thus cause health problems.

  5. Finite element crash simulations of the human body: Passive and active muscle modelling

    Indian Academy of Sciences (India)

    S Mukherjee; A Chawla; B Karthikeyan; A Soni

    2007-08-01

    Conventional dummy based testing procedures suffer from known limitations. This report addresses issues in finite element human body models in evaluating pedestrian and occupant crash safety measures. A review of material properties of soft tissues and characterization methods show a scarcity of material properties for characterizing soft tissues in dynamic loading. Experiments imparting impacts to tissues and subsequent inverse finite element mapping to extract material properties are described. The effect of muscle activation due to voluntary and non-voluntary reflexes on injuries has been investigated through finite element modelling.

  6. Early activation of the coagulation system during lower body negative pressure

    DEFF Research Database (Denmark)

    Zaar, M; Johansson, P I; Nielsen, L B;

    2009-01-01

    We considered that a moderate reduction of the central blood volume (CBV) may activate the coagulation system. Lower body negative pressure (LBNP) is a non-invasive means of reducing CBV and, thereby, simulates haemorrhage. We tested the hypothesis that coagulation markers would increase following...... moderate hypovolemia by exposing 10 healthy male volunteers to 10 min of 30 mmHg LBNP. Thoracic electrical impedance increased during LBNP (by 2.6 +/- 0.7 Omega, mean +/- SD; P rate was unchanged during LBNP, while mean arterial pressure decreased (84 +/- 5 to 80...

  7. Design of continuous circulation sub for gas drilling and the mechanical analysis on the sub body

    Directory of Open Access Journals (Sweden)

    Ding Feng

    2016-01-01

    Full Text Available Gas drilling, as an important part of underbalanced drilling, can increase drilling speed. But in the process of conventional gas drilling, it tends to cause cutting settlement, borehole collapse, sticking and other safety hazards because gas circulation has to be interrupted. Therefore, this paper presents a continuous circulation sub which can be installed and removed easily. With this sub, gas circulation will not be interrupted when drilling tools are connected and removed. This sub is composed of body, main valve, bypass valve and side entry sub. The structure design of its key components (i.e. main and bypass valves were fulfilled. Based on statics analysis on the sub body, its force situations under extension, torsion and internal pressure were simulated by using the ANSYS finite element analysis software. It is shown that its stress distribution trend is consistent with its elastic–plastic mechanics analysis results. Stress concentrates around the two round holes of the sub body, and the maximum deformation amount is still at the stage of elastic deformation. The analysis results are in line with the elastic–plastic mechanics analysis results, and the requirement of body strength is satisfied. This paper provides a new program to guarantee the drilling safety of extended-reach wells, underbalanced wells and narrow-density window wells.

  8. Measurement of lean body mass using bioelectrical impedance analysis: a consideration of the pros and cons.

    Science.gov (United States)

    Sergi, Giuseppe; De Rui, Marina; Stubbs, Brendon; Veronese, Nicola; Manzato, Enzo

    2016-08-27

    The assessment of body composition has important applications in the evaluation of nutritional status and estimating potential health risks. Bioelectrical impedance analysis (BIA) is a valid method for the assessment of body composition. BIA is an alternative to more invasive and expensive methods like dual-energy X-ray absorptiometry, computerized tomography, and magnetic resonance imaging. Bioelectrical impedance analysis is an easy-to-use and low-cost method for the estimation of fat-free mass (FFM) in physiological and pathological conditions. The reliability of BIA measurements is influenced by various factors related to the instrument itself, including electrodes, operator, subject, and environment. BIA assumptions beyond its use for body composition are the human body is empirically composed of cylinders, FFM contains virtually all the water and conducting electrolytes in the body, and its hydration is constant. FFM can be predicted by BIA through equations developed using reference methods. Several BIA prediction equations exist for the estimation of FFM, skeletal muscle mass (SMM), or appendicular SMM. The BIA prediction models differ according to the characteristics of the sample in which they have been derived and validated in addition to the parameters included in the multiple regression analysis. In choosing BIA equations, it is important to consider the characteristics of the sample in which it has been developed and validated, since, for example, age- and ethnicity-related differences could sensitively affect BIA estimates.

  9. Geometric dimension model of virtual astronaut body for ergonomic analysis of man-machine space system

    Science.gov (United States)

    Qianxiang, Zhou

    2012-07-01

    It is very important to clarify the geometric characteristic of human body segment and constitute analysis model for ergonomic design and the application of ergonomic virtual human. The typical anthropometric data of 1122 Chinese men aged 20-35 years were collected using three-dimensional laser scanner for human body. According to the correlation between different parameters, curve fitting were made between seven trunk parameters and ten body parameters with the SPSS 16.0 software. It can be concluded that hip circumference and shoulder breadth are the most important parameters in the models and the two parameters have high correlation with the others parameters of human body. By comparison with the conventional regressive curves, the present regression equation with the seven trunk parameters is more accurate to forecast the geometric dimensions of head, neck, height and the four limbs with high precision. Therefore, it is greatly valuable for ergonomic design and analysis of man-machine system.This result will be very useful to astronaut body model analysis and application.

  10. Facebook photo activity associated with body image disturbance in adolescent girls.

    Science.gov (United States)

    Meier, Evelyn P; Gray, James

    2014-04-01

    The present study examined the relationship between body image and adolescent girls' activity on the social networking site (SNS) Facebook (FB). Research has shown that elevated Internet "appearance exposure" is positively correlated with increased body image disturbance among adolescent girls, and there is a particularly strong association with FB use. The present study sought to replicate and extend upon these findings by identifying the specific FB features that correlate with body image disturbance in adolescent girls. A total of 103 middle and high school females completed questionnaire measures of total FB use, specific FB feature use, weight dissatisfaction, drive for thinness, thin ideal internalization, appearance comparison, and self-objectification. An appearance exposure score was calculated based on subjects' use of FB photo applications relative to total FB use. Elevated appearance exposure, but not overall FB usage, was significantly correlated with weight dissatisfaction, drive for thinness, thin ideal internalization, and self-objectification. Implications for eating disorder prevention programs and best practices in researching SNSs are discussed.

  11. Physical activity practice, body image and visual impairment: a comparison between Brazilian and Italian children and adolescents.

    Science.gov (United States)

    Greguol, Márcia; Gobbi, Erica; Carraro, Attilio

    2014-01-01

    The aim of this study was to analyze the physical activity and body image of children and adolescents with visual impairment (VI) in Brazil and Italy. For this, 41 children and adolescents with VI (19 Brazilian and 22 Italian) aged 10.22 ± 2.19 years old (18 girls and 23 boys) answered the Physical Activity Questionnaire for Children (PAQ-C), the Offer Self-Image Questionnaire (OSIQ), and an instrument with information about the disability, body weight and height. We analyzed the relationship between data from PAQ-C and OSIQ, as well as the gender, level of disability (blindness or low vision) and country using independent Mann-Whitney test. Body mass index (BMI) values were higher for Brazilian youths, with more than half of them classified as overweight and obese. Italian youths exhibited values of body image that were more positive and only 27% presented overweight or obesity. Blind children and adolescents were less active than those with low vision, but no differences were found between countries or genders. In Brazil, we detected significant correlations (p>0.05) between physical activity, body image and BMI, which more active youths presenting lower values of BMI and a better perception of body image. Physical activity seems to have a positive influence on body image and BMI for children and adolescents with VI, thus it should be encouraged especially for those with higher disability degrees.

  12. Statistical and Multidimensional Body Composition Parameter Analysis in Young Childhood Cancer Survivors

    Directory of Open Access Journals (Sweden)

    Topczewska Magdalena

    2014-12-01

    Full Text Available This article concerns the problem of assessing selected body compo- sition parameters after completion of antitumor therapy and comparing them with the same parameters of healthy children. A high percentage of overweight and obesity, as well as abnormal fat distribution in convalescents with cancer shows a significant adverse effect of therapy on body composition and suggests the need for early intervention in terms of diet and exercise, which would help patients to quickly achieve the proper parameters of body composition. Two main problems will be mentioned during the presented data analysis. Firstly, in each group there was a small number of observations. Because of this, the real differences between examined subgroups may have been omitted. Secondarily, many variables are correlated and are not normally distributed. Therefore, be- side the standard statistical tests to compare two groups, principal component analysis was applied to reduce the dimensions of the attribute space and to attempt to classify two groups of patients.

  13. Lipoprotein-associated phospholipase A2 (Lp-PLA2 activity, platelet-activating factor acetylhydrolase (PAF-AH in leukocytes and body composition in healthy adults

    Directory of Open Access Journals (Sweden)

    Pitsavos Christos

    2009-06-01

    Full Text Available Abstract Background Lipoprotein-associated phospholipase A2 (Lp-PLA2 also known as serum platelet activating factor acetylhydrolase (PAF-AH activity constitutes a novel risk marker for cardiovascular disease. Leukocytes constitute one main cellular source of circulating Lp-PLA2. The aim of the present study was to evaluate the association of both serum and leukocyte PAF-AH activities with fat distribution and lean tissue. One hundred healthy volunteers without cardiovascular disease history participated in this study (n = 52 men, 44 ± 13 years and n = 48 women, 43 ± 13 years. Body composition was assessed with dual-energy X-ray absorptiometry, while anthropometrical indices were also measured. The activity of Lp-PLA2 and levels of lipid and glycemic parameters were determined in fasting samples. Results Mean Lp-PLA2 activity was 24.8 ± 4.5 and 19.6 ± 5.0 nmol/min/mL in men and women, respectively (P 2 activity in men after adjusting for LDL-cholesterol, age, smoking, hs-CRP and physical activity, whereas no associations were found with PAF-AH leukocyte homogenates activity. Hierarchical analysis revealed that the variables with the highest explanatory ability of Lp-PLA2 activity in men, were DXA deriving L1–L4 region of interest and arms fat (increase in R2 = 0.136, P = 0.005 and increase in R2 = 0.118, P = 0.009, respectively, followed by trunk fat and total fat. In women, no association of body composition variables with Lp-PLA2 nor PAF-AH leukocyte homogenates activity was found. Conclusion Lp-PLA2 activity is differentiated across levels of adiposity and topology of adipose tissue, whereas no association was found regarding PAF-AH leukocyte homogenates activity. Our findings suggest that Lp-PLA2 may compensate for the adiposity-associated increases in inflammatory and oxidative burden, in men.

  14. Noise-based body-wave seismic tomography in an active underground mine.

    Science.gov (United States)

    Olivier, G.; Brenguier, F.; Campillo, M.; Lynch, R.; Roux, P.

    2014-12-01

    Over the last decade, ambient noise tomography has become increasingly popular to image the earth's upper crust. The seismic noise recorded in the earth's crust is dominated by surface waves emanating from the interaction of the ocean with the solid earth. These surface waves are low frequency in nature ( noise recorded at higher frequencies are typically from anthropogenic sources, which are short lived, spatially unstable and not well suited for constructing seismic Green's functions between sensors with conventional cross-correlation methods. To examine the use of ambient noise tomography for smaller scale applications, continuous data were recorded for 5 months in an active underground mine in Sweden located more than 1km below surface with 18 high frequency seismic sensors. A wide variety of broadband (10 - 3000 Hz) seismic noise sources are present in an active underground mine ranging from drilling, scraping, trucks, ore crushers and ventilation fans. Some of these sources generate favorable seismic noise, while others are peaked in frequency and not usable. In this presentation, I will show that the noise generated by mining activity can be useful if periods of seismic noise are carefully selected. Although noise sources are not temporally stable and not evenly distributed around the sensor array, good estimates of the seismic Green's functions between sensors can be retrieved for a broad frequency range (20 - 400 Hz) when a selective stacking scheme is used. For frequencies below 100 Hz, the reconstructed Green's functions show clear body-wave arrivals for almost all of the 153 sensor pairs. The arrival times of these body-waves are picked and used to image the local velocity structure. The resulting 3-dimensional image shows a high velocity structure that overlaps with a known ore-body. The material properties of the ore-body differ from the host rock and is likely the cause of the observed high velocity structure. For frequencies above 200 Hz, the

  15. Height and body mass influence on human body outlines: a quantitative approach using an elliptic Fourier analysis.

    Science.gov (United States)

    Courtiol, Alexandre; Ferdy, Jean Baptiste; Godelle, Bernard; Raymond, Michel; Claude, Julien

    2010-05-01

    Many studies use representations of human body outlines to study how individual characteristics, such as height and body mass, affect perception of body shape. These typically involve reality-based stimuli (e.g., pictures) or manipulated stimuli (e.g., drawings). These two classes of stimuli have important drawbacks that limit result interpretations. Realistic stimuli vary in terms of traits that are correlated, which makes it impossible to assess the effect of a single trait independently. In addition, manipulated stimuli usually do not represent realistic morphologies. We describe and examine a method based on elliptic Fourier descriptors to automatically predict and represent body outlines for a given set of predicted variables (e.g., sex, height, and body mass). We first estimate whether these predictive variables are significantly related to human outlines. We find that height and body mass significantly influence body shape. Unlike height, the effect of body mass on shape differs between sexes. Then, we show that we can easily build a regression model that creates hypothetical outlines for an arbitrary set of covariates. These statistically computed outlines are quite realistic and may be used as stimuli in future studies.

  16. A body-fixed-sensor-based analysis of power during sit-to-stand movements

    NARCIS (Netherlands)

    Zijlstra, Wiebren; Bisseling, Robertus Wilhelmus; Schlumbohm, Stephan; Baldus, Heribert

    2010-01-01

    This study presents an analysis of power exertion for lifting the body's centre of mass (CoM) during rising from a chair. Five healthy young (21-44 years) and 12 healthy older (70-79 years) subjects performed sit-to-stand (STS) movements while data were measured with force-plates underneath chair an

  17. Implementation of gamma-ray instrumentation for solid solar system bodies using neutron activation method

    Energy Technology Data Exchange (ETDEWEB)

    Litvak, M.L., E-mail: litvak@mx.iki.rssi.ru [Space Research Institute, RAS, Moscow 117997 (Russian Federation); Golovin, D.V. [Space Research Institute, RAS, Moscow 117997 (Russian Federation); Jun, I. [Jet Propulsion Laboratory, Pasadena, CA (United States); Kozyrev, A.S.; Mitrofanov, I.G.; Sanin, A.B. [Space Research Institute, RAS, Moscow 117997 (Russian Federation); Shvetsov, V.N.; Timoshenko, G.N.; Zontikov, A. [Joint Institute for Nuclear Research, Dubna (Russian Federation)

    2016-06-21

    In this paper we present the results of ground tests performed with a flight model and with industry prototypes of passive and active gamma ray spectrometers with the objective of understanding their capability to distinguish the elemental composition of planetary bodies in the solar system. The gamma instrumentation, which was developed for future space missions was used in the measurements at a special ground test facility where a simulant of planetary material was fabricated with a martian-like composition. In this study, a special attention was paid to the gamma lines from activation reaction products generated by a pulsed neutron generator. The instrumentation was able to detect and identify gamma lines attributed to O, Na, Mg, Al, Si, K, Ca and Fe.

  18. Antioxidant and Antityrosinase Activities of Various Extracts from the Fruiting Bodies of Lentinus lepideus

    Directory of Open Access Journals (Sweden)

    Tae Soo Lee

    2011-03-01

    Full Text Available Lentinus lepideus is an edible mushroom currently available in Korea. The acetone, methanol and hot water extracts were prepared and assayed for their antioxidant and antityrosinase inhibitory activities. The hot water extract showed the strongest β-carotene-linoleic acid inhibition compared to the other extracts. At 8 mg/mL, the methanolic extract showed a high reducing power of 1.21. The acetone and methanol extracts were more effective in scavenging DPPH radicals than the hot water extract. The strongest chelating effect was obtained from the methanolic extract. Xanthine oxidase and tyrosinase inhibitory activities of the acetonic, methanol and hot water extracts increased with increasing concentration. Gallic acid, chlorogenic acid, vanillin, naringin, naringenin, formononetin, and biochanin-A were detected in the acetonitrile and hydrochloric acid (5:1 solvent extract. This study suggests that fruiting bodies of L. lepideus can potentially be used as a readily accessible source of natural antioxidants.

  19. Breakdown of the equivalence between active gravitational mass and energy for a quantum body

    CERN Document Server

    Lebed, Andrei G

    2016-01-01

    We determine active gravitational mass operator of the simplest composite quantum body - a hydrogen atom - within the semiclassical approach to the Einstein equation for a gravitational field. We show that the expectation value of the mass is equivalent to energy for stationary quantum states. On the other hand, it occurs that, for quantum superpositions of stationary states with constant expectation values of energy, the expectation values of the gravitational mass exhibit time-dependent oscillations. This breaks the equivalence between active gravitational mass and energy and can be observed as a macroscopic effect for a macroscopic ensemble of coherent quantum states of the atoms. The corresponding experiment could be the first direct observation of quantum effects in General Relativity.

  20. STR analysis of human DNA from maggots fed on decomposing bodies: Assessment of the time period for successful analysis

    Directory of Open Access Journals (Sweden)

    Daniel Gachuiri Njau

    2016-09-01

    Full Text Available Frequently, forensic entomology is applied in the use of insect maggots for the identification of specimens or remains of humans. Maggot crop analysis could be valuable in criminal investigations when maggots are found at a crime scene and a corpse is absent. Human short tandem repeat (STR has previously been used to support the association of maggots to a specific corpse but not in the period at which the body has been decomposing. The aim of this research was to assess the time period for successful STR analyses of human DNA from third instar maggots (Protophormia terraenovae obtained from decomposing human corpses as well as to investigate the human DNA turnover and degradation in the maggot crop after they are removed from food and/or are fed on a beef (a new/different food source. Results showed that the amount of human DNA recovered from maggots decreased with time in all cases. For maggots fed on beef, the human DNA could only be recovered up to day two and up to day four for the starved maggots. STR analyses of human DNA from maggots’ crop content using 16 loci generated profiles that matched those of reference samples although some of the alleles were not amplifiable therefore generating partial profiles for the samples starved for 4 days and those fed on beef. This may be due to nuclease activity present in the gut of larvae that may have caused degradation of DNA and consequently reduction in DNA yield. It was possible to identify the decomposing body using STRs as markers.

  1. Reciprocal effects among changes in weight, body image, and other psychological factors during behavioral obesity treatment: a mediation analysis

    Directory of Open Access Journals (Sweden)

    Barata José T

    2009-02-01

    Full Text Available Abstract Background Changes in body image and subjective well-being variables (e.g. self-esteem are often reported as outcomes of obesity treatment. However, they may, in turn, also influence behavioral adherence and success in weight loss. The present study examined associations among obesity treatment-related variables, i.e., change in weight, quality of life, body image, and subjective well-being, exploring their role as both mediators and outcomes, during a behavioral obesity treatment. Methods Participants (BMI = 31.1 ± 4.1 kg/m2; age = 38.4 ± 6.7 y were 144 women who attended a 12-month obesity treatment program and a comparison group (n = 49, who received a general health education program. The intervention included regular group meetings promoting lasting behavior changes in physical activity and dietary intake. Body image, quality of life, subjective well-being, and body weight were measured at baseline and treatment's end. Mediation was tested by multiple regression and a resampling approach to measure indirect effects. Treatment group assignment was the independent variable while changes in weight and in psychosocial variables were analyzed alternatively as mediators and as dependent variables. Results At 12 months, the intervention group had greater weight loss (-5.6 ± 6.8% vs. -1.2 ± 4.6%, p Conclusion Changes in weight and body image may reciprocally affect each other during the course of behavioral obesity treatment. No evidence of reciprocal relationships was found for the other models under analysis; however, weight changes partially explained the effects of treatment on quality of life and self-esteem. Weight and psychosocial changes co-occur during treatment and will probably influence each other dynamically, in ways not yet adequately understood. Results from this study support the inclusion of intervention contents aimed at improving body image in weight management programs.

  2. Evaluation of upper body muscle activity during cardiopulmonary resuscitation performance in simulated microgravity

    Science.gov (United States)

    Waye, A. B.; Krygiel, R. G.; Susin, T. B.; Baptista, R.; Rehnberg, L.; Heidner, G. S.; de Campos, F.; Falcão, F. P.; Russomano, T.

    2013-09-01

    Performance of efficient single-person cardiopulmonary resuscitation (CPR) is vital to maintain cardiac and cerebral perfusion during the 2-4 min it takes for deployment of advanced life support during a space mission. The aim of the present study was to investigate potential differences in upper body muscle activity during CPR performance at terrestrial gravity (+1Gz) and in simulated microgravity (μG). Muscle activity of the triceps brachii, erector spinae, rectus abdominis and pectoralis major was measured via superficial electromyography in 20 healthy male volunteers. Four sets of 30 external chest compressions (ECCs) were performed on a mannequin. Microgravity was simulated using a body suspension device and harness; the Evetts-Russomano (ER) method was adopted for CPR performance in simulated microgravity. Heart rate and perceived exertion via Borg scores were also measured. While a significantly lower depth of ECCs was observed in simulated microgravity, compared with +1Gz, it was still within the target range of 40-50 mm. There was a 7.7% decrease of the mean (±SEM) ECC depth from 48 ± 0.3 mm at +1Gz, to 44.3 ± 0.5 mm during microgravity simulation (p muscular and cardiovascular deconditioning that occurs during space travel.

  3. Algorithm for Active Suppression of Radiation and Acoustical Scattering Fields by Some Physical Bodies in Liquids

    Directory of Open Access Journals (Sweden)

    Vladimir V. Arabadzhi

    2009-03-01

    Full Text Available An algorithm for the suppression of the radiation and scattering fields created by vibration of the smooth closed surface of a body of arbitrary shape placed in a liquid is designed and analytically explored. The frequency range of the suppression allows for both large and small wave sizes on the protected surface. An active control system is designed that consists of: (a a subsystem for fast formation of a desired distribution of normal oscillatory velocities or displacements (on the basis of pulsed Huygens' sources and (b a subsystem for catching and targeting of incident waves on the basis of a grid (one layer of monopole microphones, surrounding the surface to be protected. The efficiency and stability of the control algorithm are considered. The algorithm forms the control signal during a time much smaller than the minimum time scale of the waves to be damped. The control algorithm includes logical and nonlinear operations, thus excluding interpretation of the control system as a traditional combination of linear electric circuits, where all parameters are constant (in time. This algorithm converts some physical body placed in a liquid into one that is transparent to a special class of incident waves. The active control system needs accurate information on its geometry, but does not need either prior or current information about the vibroacoustical characteristics of the protected surface, which in practical cases represents a vast amount of data.

  4. Physical Activity and Compensation of Body Posture Disorders in Children Aged Seven

    Directory of Open Access Journals (Sweden)

    Hricková Katarína

    2016-09-01

    Full Text Available Introduction. Physical activity is an indelible part of human life, but the impact of industrial changes on society has led to a hypokinetic lifestyle not only in adults but also in children and youth. This paper aims to present the results of a study of the body posture of 7-year-olds, which is an essential part of their physical development evaluation. The aim of our study was to expand our knowledge of the occurrence of body posture disorders in 7-year-olds, as well as to develop an appropriate movement programme which would help improve the current situation. Material and methods. The research sample consisted of 393 first-graders from 4 grammar schools in Kosice. We used muscle testing according to Janda and Tichy to obtain data on individual muscle weaknesses and postural deviations. Results. Our research confirmed the findings of several other researchers who had pointed out that muscle weaknesses and postural deviations can be observed already in preschoolers. Due to a lack of physical activity and movement, muscle weakness in preschool children results in more serious health issues at school age and later in adulthood. Conclusions. We managed to stabilise and even to correct the weaknesses we observed by implementing a movement programme focusing on the diagnosed muscle weakness.

  5. Modelling soft tissue for kinematic analysis of multi-segment human body models.

    Science.gov (United States)

    Benham, M P; Wright, D K; Bibb, R

    2001-01-01

    Traditionally biomechanical models represent the musculoskeletal system by a series of rigid links connected by rigidly defined rotational joints. More recently though the mechanics of joints and the action of soft tissues has come under closer scrutiny: biomechanical models might now include a full range of physiological structures. However, soft tissue representation, within multi-segment human body models, presents significant problems; not least in computational speed. We present a method for representing soft tissue physiology which provides for soft tissue wrapping around multiple bony objects; while showing forces at the insertion points, as well as normal reactions due to contact between the soft and bony tissues. These soft tissue representations may therefore be used to constrain the joint, as ligaments would, or to generate motion, like a muscle, so that joints may be modelled which more accurately simulate musculoskeletal motion in all degrees of freedom--rotational and translational. This method produces soft tissues that do not need to be tied to a certain path or route between the bony structures, but may move with the motion of the model; demonstrating a more realistic analysis of soft tissue activity in the musculoskeletal system. The combination of solid geometry models of the skeletal structure, and these novel soft tissue representations, may also provide a useful approach to synthesised human motion.

  6. Accuracy of segmental bioelectrical impedance analysis for predicting body composition in pre- and postmenopausal women.

    Science.gov (United States)

    Tanaka, Noriko I; Hanawa, Satoshi; Murakami, Haruka; Cao, Zhen-Bo; Tanimoto, Michiya; Sanada, Kiyoshi; Miyachi, Motohiko

    2015-01-01

    This study aimed to compare the accuracy for predicting body composition using single-frequent segmental bioelectrical impedance analysis (BIA) between pre- and postmenopausal women. A total f 559 Japanese women aged 30-88yr were divided into 4 groups by questionnaire: natural menopause, pathological menopause, regular menstruation, or irregular menstruation. The measurement values by dual-energy X-ray absorptiometry were used as a reference of the body composition. In terms of the results, regardless of the menopausal status, BIA slightly but significantly overestimated the percentage of body fat (standard error of estimate: 5.3%-6.7%) and the leg lean soft tissue mass (LSTM; 5.1%-6.1%), and underestimated the LSTM in the whole body (6.2%-7.6%) and arm (2.8%-3.7%). The absolute values of the predictive error for leg LSTM were significantly higher in postmenopausal groups than in the premenopausal ones. The corresponding values for the whole body and arm LSTM, and the percentage of body fat were higher in premenopausal groups than in postmenopausal ones. In conclusion, the predictive accuracy of BIA for postmenopausal women is not inferior to that for premenopausal ones, unless we target the leg LSTM.

  7. Changes in the visceral fat bodies associated with haematopoiesis and lipid metabolism, in relation to tail regeneration in the scincid lizard, Mabuya carinata: a histomorphological analysis.

    Science.gov (United States)

    Shah, R V; Kinariwala, R V; Ramachandran, A V

    1982-01-01

    In order to understand the role of visceral fat bodies in regeneration, a histomorphological analysis of the fat bodies in Mabuya during its tail regeneration was undertaken. The investigation revealed 2 interesting aspects; a visible shrinkage of the fat bodies and a fall in the histosomatic index (HSI), as well as an enhancement in haemopoietic activity and infiltration of lymphocytes in the fat bodies during the 1st 7 days of tail regeneration. These observations are taken to indicate the involvement of visceral fat bodies in the regenerative mechanics. The appearance of lymphocytes on the 5th and 7th days and their subsequent disappearance together with lipid depletion are construed from the functioning of lymphocytes in lipid transport during their passage to the wound site.

  8. Impact of the use of different skinfold calipers for the analysis of the body composition

    Directory of Open Access Journals (Sweden)

    Cyrino Edilson Serpeloni

    2003-01-01

    Full Text Available With the advances in the studies of body composition, it has been observed that several factors can interfere with the estimates of relative body fat using the skinfold thicknesses method. Therefore, the purpose of this study was to investigate the impact of the use of different skinfold calipers for the analysis of body composition by skinfold thicknesses measurements. Two hundred and fifty nine male subjects (23.3 ± 2.9 years took part of the study. Nine skinfold thicknesses were measured (abdominal, subscapular, suprailiac, triceps, biceps, midaxillary, chest, medial calf, and thigh using the Lange (USA and the Cescorf (Brazil calipers with accuracy of 1.0 and 0.1 mm, respectively. Significant differences were found in the comparison between the two calipers on all the investigated skinfold thicknesses (1.8 to 31.0% with highest values obtained by the Lange caliper (p < 0.01. When these values were applied to four different predictive equations, developed by different researchers, the body fat estimate was significantly modified (p < 0.01, resulting in differences of 5.2 to 6.9%. Results indicate that the use of different skinfold calipers may maximize the errors of estimation produced by different predictive equations used for the analysis of body composition.

  9. Analysis of adipose tissue distribution using whole-body magnetic resonance imaging

    Science.gov (United States)

    Wald, Diana; Schwarz, Tobias; Dinkel, Julien; Delorme, Stefan; Teucher, Birgit; Kaaks, Rudolf; Meinzer, Hans-Peter; Heimann, Tobias

    2011-03-01

    Obesity is an increasing problem in the western world and triggers diseases like cancer, type two diabetes, and cardiovascular diseases. In recent years, magnetic resonance imaging (MRI) has become a clinically viable method to measure the amount and distribution of adipose tissue (AT) in the body. However, analysis of MRI images by manual segmentation is a tedious and time-consuming process. In this paper, we propose a semi-automatic method to quantify the amount of different AT types from whole-body MRI data with less user interaction. Initially, body fat is extracted by automatic thresholding. A statistical shape model of the abdomen is then used to differentiate between subcutaneous and visceral AT. Finally, fat in the bone marrow is removed using morphological operators. The proposed method was evaluated on 15 whole-body MRI images using manual segmentation as ground truth for adipose tissue. The resulting overlap for total AT was 93.7% +/- 5.5 with a volumetric difference of 7.3% +/- 6.4. Furthermore, we tested the robustness of the segmentation results with regard to the initial, interactively defined position of the shape model. In conclusion, the developed method proved suitable for the analysis of AT distribution from whole-body MRI data. For large studies, a fully automatic version of the segmentation procedure is expected in the near future.

  10. Resting energy expenditure and body composition in children with cancer: indirect calorimetry and bioimpedance analysis

    Directory of Open Access Journals (Sweden)

    M. V. Konovalova

    2014-07-01

    Full Text Available Resting energy expenditure (REE by indirect calorimetry and body composition by bioimpedance analysis are studied in three groups of children aged 5–18 years. Group 1 (n = 181 – patients in remission of cancer, group 2 (n = 55 – children with oncology diseases receiving chemotherapy or who are in the early period after hematopoietic stem cell transplantation, group 3 (n = 63 – children with non-malignant diseases of the gastrointestinal tract. To eliminate the influence of age and gender on the intergroup comparisons, body composition parameters were expressed as standardized values (z-scores relative to a reference group of healthy Russian children (n = 138,191. Group 1 was characterized by excess fat content with intact lean body mass, and groups 2 and 3 by protein depletion, more pronounced in Group 2 with a higher percentage of body fat. All used conventional formulas (WHO, Harris–Benedict and others in groups 1 and 3 underestimated REE as compared with indirect calorimetry. A new formula for REE, giving an unbiased estimate in the group 1 was proposed: REE (kcal/day = 28.7 × BCM (kg +10.5 × Height (cm – 38.6 × Age (years – 134, where BCM – body cell mass according to bioimpedance analysis (R2 = 0.67, the standard deviation of 196 kcal/day.

  11. Small-Body Extensions for the Satellite Orbit Analysis Program (SOAP)

    Science.gov (United States)

    Carnright, Robert; Stodden, David; Coggi, John

    2008-01-01

    An extension to the SOAP software allows users to work with tri-axial ellipsoid-based representations of planetary bodies, primarily for working with small, natural satellites, asteroids, and comets. SOAP is a widely used tool for the visualization and analysis of space missions. The small body extension provides the same visualization and analysis constructs for use with small bodies. These constructs allow the user to characterize satellite path and instrument cover information for small bodies in both 3D display and numerical output formats. Tri-axial ellipsoids are geometric shapes the diameters of which are different in each of three principal x, y, and z dimensions. This construct provides a better approximation than using spheres or oblate spheroids (ellipsoids comprising two common equatorial diameters as a distinct polar diameter). However, the tri-axial ellipsoid is considerably more difficult to work with from a modeling perspective. In addition, the SOAP small-body extensions allow the user to actually employ a plate model for highly irregular surfaces. Both tri-axial ellipsoids and plate models can be assigned to coordinate frames, thus allowing for the modeling of arbitrary changes to body orientation. A variety of features have been extended to support tri-axial ellipsoids, including the computation and display of the spacecraft sub-orbital point, ground trace, instrument footprints, and swathes. Displays of 3D instrument volumes can be shown interacting with the ellipsoids. Longitude/latitude grids, contour plots, and texture maps can be displayed on the ellipsoids using a variety of projections. The distance along an arbitrary line of sight can be computed between the spacecraft and the ellipsoid, and the coordinates of that intersection can be plotted as a function of time. The small-body extension supports the same visual and analytical constructs that are supported for spheres and oblate spheroids in SOAP making the implementation of the more

  12. Small Bodies, Big Concepts: Engaging Teachers and Their Students in Visual Analysis of Comets and Asteroids

    Science.gov (United States)

    Cobb, W. H.; Buxner, S.; Lebofsky, L. A.; Ristvey, J.; Weeks, S.; Zolensky, M.

    2011-12-01

    Small Bodies, Big Concepts is a multi-disciplinary, professional development project that engages 5th - 8th grade teachers in high end planetary science using a research-based pedagogical framework, Designing Effective Science Instruction (DESI). In addition to developing sound background knowledge with a focus on visual analysis, teachers' awareness of the process of learning new content is heightened, and they use that experience to deepen their science teaching practice. Culling from NASA E/PO educational materials, activities are sequenced to enhance conceptual understanding of big ideas in space science: what do we know, how do we know it, why do we care? Helping teachers develop a picture of the history and evolution of our understanding of the solar system, and honing in on the place of comets and asteroids in helping us answer old questions and discover new ones, teachers see the power and excitement underlying planetary science as human endeavor. Research indicates that science inquiry is powerful in the classroom and mission scientists are real-life models of science inquiry in action. Using guest scientist facilitators from the Planetary Science Institute, NASA Johnson Space Center, Lockheed Martin, and NASA E/PO professionals from McREL and NASA AESP, teachers practice framing scientific questions, using current visual data, and adapting NASA E/PO activities related to current exploration of asteroids and comets in our Solar System. Cross-curricular elements included examining research-based strategies for enhancing English language learners' ability to engage in higher order questions and a professional astronomy artist's insight into how visual analysis requires not just our eyes engaged, but our brains: comparing, synthesizing, questioning, evaluating, and wondering. This summer we pilot tested the SBBC curriculum with thirteen 5th- 10th grade teachers modeling a variety of instructional approaches over eight days. Each teacher developed lesson plans

  13. Body composition of 80-years old men and women and its relation to muscle strength, physical activity and functional ability

    DEFF Research Database (Denmark)

    Pederse, agnes N; Ovesen, Lars; Schroll, M;

    2002-01-01

    OBJECTIVE: To measure body composition and analyse the relation to muscle strength, physical activity and functional ability in healthy, old subjects, and to relate the results to an optimal BMI level for the elderly. SETTING: Subjects aged 80 years living at home from the 1914-population...... proposed guidelines for the elderly of an optimal BMI interval of 24-29 kg/m2. We found relations between body composition, muscle strength, physical activity and functional ability....

  14. Features of muscular activity at carrying out body drop by female judo-wrestlers of highly qualification

    Directory of Open Access Journals (Sweden)

    Elipkhanov S.B.

    2012-09-01

    Full Text Available The aim of this study was evaluating muscles activity at carrying out body drop, lengths of muscles and velocity of changing their lengths. Was used 2D and 3D video analysis. Three participant of Russia female national judo team (age before 23 years took part in experiment. Has been established at carrying out reception to the right side greatest changes of length are observed at left and right muscle rectus abdominis and right muscle obliquus externus abdominis, middle and lower parts of left muscle gluteus maximus, back parts of left and right muscle deltoideus. The highest velocity of contraction are noticed at muscle obliquus externus abdominis (especially at the right, middle and lower parts of left muscle gluteus maximus and middle part of left muscle deltoideus.

  15. Conference on Instrumental Activation Analysis: IAA 89

    Science.gov (United States)

    Vobecky, M.; Obrusnik, I.

    1989-05-01

    The proceedings contain 40 abstracts of papers all of which have been incorporated in INIS. The papers were centred on the applications of radioanalytical methods, especially on neutron activation analysis, x ray fluorescence analysis, PIXE analysis and tracer techniques in biology, medicine and metallurgy, measuring instruments including microcomputers, and data processing methods.

  16. Moderate-vigorous physical activity across body mass index in females: moderating effect of endocannabinoids and temperament.

    Directory of Open Access Journals (Sweden)

    Fernando Fernández-Aranda

    Full Text Available Endocannabinoids and temperament traits have been linked to both physical activity and body mass index (BMI however no study has explored how these factors interact in females. The aims of this cross-sectional study were to 1 examine differences among distinct BMI groups on daytime physical activity and time spent in moderate-vigorous physical activity (MVPA, temperament traits and plasma endocannabinoid concentrations; and 2 explore the association and interaction between MVPA, temperament, endocannabinoids and BMI.Physical activity was measured with the wrist-worn accelerometer Actiwatch AW7, in a sample of 189 female participants (43 morbid obese, 30 obese, and 116 healthy-weight controls. The Temperament and Character Inventory-Revised questionnaire was used to assess personality traits. BMI was calculated by bioelectrical impedance analysis via the TANITA digital scale. Blood analyses were conducted to measure levels of endocannabinoids and endocannabinoid-related compounds. Path-analysis was performed to examine the association between predictive variables and MVPA.Obese groups showed lower MVPA and dysfunctional temperament traits compared to healthy-weight controls. Plasma concentrations of 2-arachidonoylglyceryl (2-AG were greater in obese groups. Path-analysis identified a direct effect between greater MVPA and low BMI (b = -0.13, p = .039 and high MVPA levels were associated with elevated anandamide (AEA levels (b = 0.16, p = .049 and N-oleylethanolamide (OEA levels (b = 0.22, p = .004, as well as high Novelty seeking (b = 0.18, p<.001 and low Harm avoidance (b = -0.16, p<.001.Obese individuals showed a distinct temperament profile and circulating endocannabinoids compared to controls. Temperament and endocannabinoids may act as moderators of the low MVPA in obesity.

  17. The three-step process of self-objectification: potential implications for adolescents' body consciousness during sexual activity.

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    Vandenbosch, Laura; Eggermont, Steven

    2014-01-01

    A three-wave panel study with intervals of six months was conducted to examine the relationships between internalization of appearance ideals, body surveillance, valuing appearance over competence, and body consciousness during sexual activity among 238 Belgian adolescents who had engaged in sexual intercourse. Consistent with predictions, structural equation modeling indicated that greater internalization of appearance ideals at Wave 1 contributed to increased body surveillance and valuing appearance over competence at Wave 2. Body surveillance at Wave 2 and internalization at Wave 1 predicted higher body consciousness during sexual activity at Wave 3. Gender did not moderate these results, as model paths were similar in strength for girls and boys. These results further implicate the consequences of internalizing sociocultural practices that objectify boys and girls regarding adolescents' initial sexual experiences.

  18. Daily scheduled high fat meals moderately entrain behavioral anticipatory activity, body temperature, and hypothalamic c-Fos activation.

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    Christian M Gallardo

    Full Text Available When fed in restricted amounts, rodents show robust activity in the hours preceding expected meal delivery. This process, termed food anticipatory activity (FAA, is independent of the light-entrained clock, the suprachiasmatic nucleus, yet beyond this basic observation there is little agreement on the neuronal underpinnings of FAA. One complication in studying FAA using a calorie restriction model is that much of the brain is activated in response to this strong hunger signal. Thus, daily timed access to palatable meals in the presence of continuous access to standard chow has been employed as a model to study FAA in rats. In order to exploit the extensive genetic resources available in the murine system we extended this model to mice, which will anticipate rodent high fat diet but not chocolate or other sweet daily meals (Hsu, Patton, Mistlberger, and Steele; 2010, PLoS ONE e12903. In this study we test additional fatty meals, including peanut butter and cheese, both of which induced modest FAA. Measurement of core body temperature revealed a moderate preprandial increase in temperature in mice fed high fat diet but entrainment due to handling complicated interpretation of these results. Finally, we examined activation patterns of neurons by immunostaining for the immediate early gene c-Fos and observed a modest amount of entrainment of gene expression in the hypothalamus of mice fed a daily fatty palatable meal.

  19. Discriminant Analysis of Raman Spectra for Body Fluid Identification for Forensic Purposes

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    Vitali Sikirzhytski

    2010-03-01

    Full Text Available Detection and identification of blood, semen and saliva stains, the most common body fluids encountered at a crime scene, are very important aspects of forensic science today. This study targets the development of a nondestructive, confirmatory method for body fluid identification based on Raman spectroscopy coupled with advanced statistical analysis. Dry traces of blood, semen and saliva obtained from multiple donors were probed using a confocal Raman microscope with a 785-nm excitation wavelength under controlled laboratory conditions. Results demonstrated the capability of Raman spectroscopy to identify an unknown substance to be semen, blood or saliva with high confidence.

  20. Effects of a recreational physical activity summer camp on body composition, metabolic syndrome and physical fitness in obese children.

    Science.gov (United States)

    Roriz DE Oliveira, Mafalda S; Teixeira Seabra, André F; Ribeiro Maia, José A

    2016-01-01

    This study sought to examine the effects of a recreational physical activity summer camp on body composition, metabolic syndrome, and physical fitness in obese children. Forty-eight children (8-10 years; Body Mass Index ≥85th percentile) completed 4-weeks of a structured recreational physical activity program summer camp (5 hours/day, 5 days/week). Over the 4-weeks, significant reductions (Psummer camp yields several body-composition, metabolic-syndrome, and physical fitness benefits in obese children and should represent an effective support for their health development.

  1. The daily pattern of heart rate, body temperature, locomotor activity, and autonomic nervous activity in congenitally bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.

    Science.gov (United States)

    Akita, Megumi; Kuwahara, Masayoshi; Nishibata, Ryoji; Mikami, Hiroki; Tsubone, Hirokazu

    2004-04-01

    We studied the characteristics of the rhythmicity of heart rate (HR), body temperature (BT), locomotor activity (LA) and autonomic nervous activity in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs. For this purpose, HR, BT, LA, and electrocardiogram (ECG) were recorded from conscious and unrestrained guinea pigs using a telemetry system. Autonomic nervous activity was analyzed by power spectral analysis of heart rate variability. Nocturnal patterns, in which the values in the dark phase (20:00-06:00) were higher than those in the light phase (06:00-20:00), were observed in HR, BT and LA in both strains of guinea pigs. The autonomic nervous activity in BHS guinea pigs showed a daily pattern, although BHR guinea pigs did not show such a rhythmicity. The high frequency (HF) power in BHS guinea pigs was higher than that in BHR guinea pigs throughout the day. Moreover, the low frequency/high frequency (LF/HF) ratio in BHS guinea pigs was lower than that in BHR guinea pigs throughout the day. These results suggest that parasympathetic nervous activity may be predominant in BHS guinea pigs.

  2. Evaluation of segmental body composition by gender in obese children using bioelectric impedance analysis method

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    İhsan Çetin

    2015-12-01

    Full Text Available Objective: In this study, it was aimed to evaluate segmental body composition of children diagnosed with obesity using bioelectrical impedance analysis method in terms of different gender. Methods: 48 children, aged between 6-15 years, 21 of whom were boys while 27 were girls, diagnosed with obesity in Erciyes University Medical Faculty Department of Pediatric Endocrinology Outpatient Clinic were included in our study from April to June in 2011. Those over 95 percentile were defined as obese group. Tanita BC-418 device was used to analyze the body composition. Results: As a result of bioelectrical impedance analysis, lean body mass and body muscle mass were found to be statistically significantly higher in obese girls compared with obese boys. However, lean mass of the left arm, left leg muscle mass and basal metabolic rate were found to be statistically significantly lower in obese girls compared with obese boys. Conclusion: Consequently, it may be suggest that segmental analysis, where gender differences are taken into account, can provide proper exercise pattern and healthy way of weight loss in children for prevention of obesity and associated diseases including obesity and type 2 diabetics and cardiovascular diseases.

  3. Prospective study of body mass index, height, physical activity and incidence of bladder cancer in US men and women.

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    Holick, Crystal N; Giovannucci, Edward L; Stampfer, Meir J; Michaud, Dominique S

    2007-01-01

    We evaluated prospectively the association between body mass index (BMI), height, recreational physical activity and the risk of bladder cancer among US adults. Data were used from 2 ongoing cohorts, the Health Professionals Follow-up Study and the Nurses' Health Study, with 3,542,012 years of follow-up and 866 incident bladder cancer cases (men = 507; women = 359) for the anthropometric analysis and 1,890,476 years of follow-up and 706 incident bladder cancer cases (men = 502; women = 204) for the physical activity analysis. Cox proportional hazard models were used to estimate incidence rate ratios (RR) and 95% confidence intervals (CI) between BMI, height, physical activity and bladder cancer risk adjusting for age, pack-years of cigarette smoking and current smoking. Estimates from each cohort were pooled using a random-effects model. We observed no association between baseline BMI and bladder cancer risk, even when we compared a BMI of > or =30 kg/m(2) to a BMI of 18-22.9 kg/m(2) [pooled multivariate (MV) RR, 1.16; 95% CI: 0.89-1.52]. A weak, but statistically significant, association was observed for the same comparison after excluding bladder cancer cases diagnosed within the first 4 years of follow-up (pooled MV RR, 1.33; 95% CI: 1.01-1.76). Height was not related to bladder cancer risk (pooled MV RR, 0.82; 95% CI: 0.65-1.03, top vs. bottom quintile). Total recreational physical activity also was not associated with the risk of bladder cancer (pooled MV RR, 0.97; 95% CI: 0.77-1.24, top vs. bottom quintile). Our findings do not support a role for BMI, height or physical activity in bladder carcinogenesis.

  4. Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model

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    Song, Jingjing; Wang, Yingwu; Teng, Meiyu; Cai, Guangsheng; Xu, Hongkai; Guo, Hanxiao; Liu, Yang; Wang, Di; Teng, Lesheng

    2015-01-01

    Cordyceps militaris has been used extensively as a crude drug and a folk tonic food in East Asia due to its various pharmacological activities. Our study aims to investigate the effect of Cordyceps militaris fruit body extract (CM) on antifatigue in mouse model. Two week CM administration significantly delayed fatigue phenomenon which is confirmed via rotating rod test, forced swimming test and forced running test. Compared to nontreated mouse, CM administration increased ATP levels and antioxidative enzymes activity and reduced the levels of lactic acid, lactic dehydrogenase, malondialdehyde, and reactive oxygen species. Further data suggests that CM-induced fatigue recovery is mainly through activating 5′-AMP-activated protein kinase (AMPK) and protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathways and regulating serum hormone level. Moreover, CM-enhanced the phosphorylation of AMPK contributes to its antioxidant effect. Our data provides experimental evidence in supporting clinical use of CM as an effective agent against fatigue. PMID:26351509

  5. Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model

    Directory of Open Access Journals (Sweden)

    Jingjing Song

    2015-01-01

    Full Text Available Cordyceps militaris has been used extensively as a crude drug and a folk tonic food in East Asia due to its various pharmacological activities. Our study aims to investigate the effect of Cordyceps militaris fruit body extract (CM on antifatigue in mouse model. Two week CM administration significantly delayed fatigue phenomenon which is confirmed via rotating rod test, forced swimming test and forced running test. Compared to nontreated mouse, CM administration increased ATP levels and antioxidative enzymes activity and reduced the levels of lactic acid, lactic dehydrogenase, malondialdehyde, and reactive oxygen species. Further data suggests that CM-induced fatigue recovery is mainly through activating 5′-AMP-activated protein kinase (AMPK and protein kinase B (AKT/mammalian target of rapamycin (mTOR pathways and regulating serum hormone level. Moreover, CM-enhanced the phosphorylation of AMPK contributes to its antioxidant effect. Our data provides experimental evidence in supporting clinical use of CM as an effective agent against fatigue.

  6. Affect differentially modulates brain activation in uni- and multisensory body-voice perception.

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    Jessen, Sarah; Kotz, Sonja A

    2015-01-01

    Emotion perception naturally entails multisensory integration. It is also assumed that multisensory emotion perception is characterized by enhanced activation of brain areas implied in multisensory integration, such as the superior temporal gyrus and sulcus (STG/STS). However, most previous studies have employed designs and stimuli that preclude other forms of multisensory interaction, such as crossmodal prediction, leaving open the question whether classical integration is the only relevant process in multisensory emotion perception. Here, we used video clips containing emotional and neutral body and vocal expressions to investigate the role of crossmodal prediction in multisensory emotion perception. While emotional multisensory expressions increased activation in the bilateral fusiform gyrus (FFG), neutral expressions compared to emotional ones enhanced activation in the bilateral middle temporal gyrus (MTG) and posterior STS. Hence, while neutral stimuli activate classical multisensory areas, emotional stimuli invoke areas linked to unisensory visual processing. Emotional stimuli may therefore trigger a prediction of upcoming auditory information based on prior visual information. Such prediction may be stronger for highly salient emotional compared to less salient neutral information. Therefore, we suggest that multisensory emotion perception involves at least two distinct mechanisms; classical multisensory integration, as shown for neutral expressions, and crossmodal prediction, as evident for emotional expressions.

  7. Risk of decline in functional activities in dementia with Lewy bodies and Alzheimer disease.

    Science.gov (United States)

    Gill, Dawn P; Koepsell, Thomas D; Hubbard, Rebecca A; Kukull, Walter A

    2011-01-01

    We examined the risk of 1-year decline in 4 everyday activities in patients with dementia with Lewy bodies (DLB), relative to patients with Alzheimer disease (AD). Data were from the National Alzheimer's Coordinating Center, gathered from 32 Alzheimer's Disease Centers. Participants (n=1880) were: aged 60+ years, demented with a primary clinical diagnosis of probable AD or DLB, and had a global Clinical Dementia Rating of 0.5 to 2. The activities were measured with the Functional Activities Questionnaire. In modified Poisson regression models adjusted for demographics, baseline activity, years from symptom onset, cognitive impairment, and comorbidities; DLB participants aged 67 to 81 years had 1.5 to 2 times increased risk of decline in performing basic kitchen tasks, engaging in games/hobbies, and paying attention/understanding, relative to AD participants of the same age (P<0.05). There was no significant difference between AD and DLB participants beyond this age range. For decline in ability to go shopping alone, there was also no significant difference between AD and DLB participants. In summary, the functional course of DLB, relative to AD, may depend on the age of the patient. These findings may provide anticipatory guidance to families and healthcare providers, which may be useful in the planning of care strategies.

  8. The Impact Analysis of Water Body Landscape Pattern on Urban Heat Island: A Case Study of Wuhan City

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    Bohan Yang

    2015-01-01

    Full Text Available Based on the LST and the landscape metrics of water body with remote sensing technique and spatial analysis, the relationship between the mean LST and the attributes of water body was revealed via Pearson’s correlation analysis and multiple stepwise regression analysis. Result showed that, in 32 class-based metrics we selected, the proportion of water body, average water body size, the isolation and fragmentation of water body, and other eight metrics have high correlation with the LST. As a resultant force, the quantity, shape, and spatial distribution of water body affect the forming of temperature. We found that the quantity and spatial pattern of city water body could be allocated reasonably to maximize its cooling effect.

  9. MoBILAB: An open source toolbox for analysis and visualization of mobile brain/body imaging data

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    Alejandro eOjeda

    2014-03-01

    Full Text Available A new paradigm for human brain imaging, mobile brain/body imaging (MoBI, involves synchronous collection of human brain activity (via electroencephalography, EEG and behavior (via body motion capture, eye tracking, etc., plus environmental events (scene and event recording to study joint brain/body dynamics supporting natural human cognition supporting performance of naturally motivated human actions and interactions in 3-D environments (Makeig et al., 2009⁠. Processing complex, concurrent, multi-modal, multi-rate data streams requires a signal-processing environment quite different from one designed to process single-modality time series data. Here we describe MoBILAB (more details available at sccn.ucsd.edu/wiki/MoBILAB, an open source, cross platform toolbox running on MATLAB (The Mathworks, Inc. that supports analysis and visualization of any mixture of synchronously recorded brain, behavioral, and environmental time series plus time-marked event stream data. MoBILAB can serve as a pre-processing environment for adding behavioral and other event markers to EEG data for further processing, and/or as a development platform for expanded analysis of simultaneously recorded data streams.

  10. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  11. USING BENCH PRESS LOAD TO PREDICT UPPER BODY EXERCISE LOADS IN PHYSICALLY ACTIVE INDIVIDUALS

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    Del P. Wong

    2013-03-01

    Full Text Available This study investigated whether loads for assistance exercises of the upper body can be predicted from the loads of the bench press exercise. Twenty-nine physically active collegiate students (age: 22.6 ± 2.5; weight training experience: 2.9 ± 2.1 years; estimated 1RM bench press: 54.31 ± 14.60 kg; 1RM: body weight ratio: 0.80 ± 0.22; BMI: 22.7 ± 2.1 kg·m-2 were recruited. The 6RM loads for bench press, barbell bicep curl, overhead dumbbell triceps extension, hammer curl and dumbbell shoulder press were measured. Test-retest reliability for the 5 exercises as determined by Pearson product moment correlation coefficient was very high to nearly perfect (0.82-0.98, p < 0.01. The bench press load was significantly correlated with the loads of the 4 assistance exercises (r ranged from 0.80 to 0.93, p < 0.01. Linear regression revealed that the bench press load was a significant (R2 range from 0.64 to 0.86, p < 0.01 predictor for the loads of the 4 assistance exercises. The following 6RM prediction equations were determined: (a Hammer curl = Bench press load (0.28 + 6.30 kg, (b Barbell biceps curl = Bench press load (0.33 + 6.20 kg, (c Overhead triceps extension = Bench press load (0.33 - 0.60 kg, and (d Dumbbell shoulder press = Bench press load (0.42 + 5.84 kg. The difference between the actual load and the predicted load using the four equations ranged between 6.52% and 8.54%, such difference was not significant. Fitness professionals can use the 6RM bench press load as a time effective and accurate method to predict training loads for upper body assistance exercises.

  12. Aero-thermal analysis of lifting body configurations in hypersonic flow

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    Kumar, Sachin; Mahulikar, Shripad P.

    2016-09-01

    The aero-thermal analysis of a hypersonic vehicle is of fundamental interest for designing its thermal protection system. The aero-thermal environment predictions over several critical regions of the hypothesized lifting body vehicle, including the stagnation region of the nose-cap, cylindrically swept leading edges, fuselage-upper, and fuselage-lower surfaces, are discussed. The drag (Λ=70°) and temperature (Λ=80°) minimized sweepback angles are considered in the configuration design of the two hypothesized lifting body shape hypersonic vehicles. The main aim of the present study is to analyze and compare the aero-thermal characteristics of these two lifting body configurations at same heat capacity. Accordingly, a Computational Fluid Dynamics simulation has been carried out at Mach number (M∞=7), H=35 km altitude with zero Angle of Attack. Finally, the material selection for thermal protection system based on these predictions and current methodology is described.

  13. Biochemical analysis of fruiting bodies of Volvariella volvacea strain Vv pk, grown on six different substrates

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    Imran Ul Haq, Muhammad Aslam Khan, Sajid Aleem Khan

    2011-11-01

    Full Text Available A local strain of Volvariella volvacea Vv pk, locally known as Chinese mushroom was cultivated on six different agricultural wastes including paddy straw, cotton waste, banana leaves, corn stovers, sugarcane baggasse and pulses straw. The study was conducted to know that how much a substrate contributes in the nutritional value of the fruiting bodies of the mushroom harvested from such substrate and to recommend the best substrate for the commercial cultivation of the mushroom with high levels of protein, crude fibre and certain other elements. The biochemical analysis of the fruiting bodies harvested from the substrates was done to estimate the moisture percentage, crude fat, protein, fiber, and ash contents. Maximum protein (34.17%, ash (10.8 and crude fiber percentage (11.9% was observed in the fruiting bodies harvested from cotton waste. So, cotton waste is recommended as an effective substrate to grow Chinese mushroom on commercial scale.

  14. Effects of wire-bottom caging on heart rate, activity and body temperature in telemetry-implanted rats.

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    Giral, Marta; García-Olmo, Dolores C; Kramer, Klaas

    2011-10-01

    Some experimental procedures are associated with placement of animals in wire-bottom cages. The goal of this study was to evaluate stress-related physiological parameters (heart rate [HR], body temperature [BT], locomotor activity [LA], body weight [BW] and food consumption) in rats under two housing conditions, namely in wire-bottom cages and in bedding-bottom cages. Telemetry devices were surgically implanted in male Sprague-Dawley rats. HR, BT and LA were recorded at 5 min intervals. Analysis under each housing condition was performed from 16:00 to 08:00 h of the following day (4 h light, 12 h dark). During almost all of the light phase, the HR of rats housed in wire-bottom cages remained high (371 ± 35 bpm; mean ± SD; n = 6) and was significantly different from that of rats housed in bedding-bottom cages (340 ± 29 bpm; n = 6; P wire-bottom cages, BT tended to fluctuate more widely during the dark phase. LA decreased when animals were housed in wire-bottom cages, in particular during the dark phase. Moreover, there was a significant difference with respect to the gain in BW: BW of rats housed in bedding-bottom cages increased 12 ± 2 g, whereas that of rats in wire-bottom cages decreased by 2 ± 3 g (P wire-bottom cages overnight leads to immediate alterations of HR, BW and LA, which might be related to a stress response.

  15. Expression and purification of biologically active recombinant human paraoxonase 1 from inclusion bodies of Escherichia coli.

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    Bajaj, Priyanka; Tripathy, Rajan K; Aggarwal, Geetika; Pande, Abhay H

    2015-11-01

    Human PON1 (h-PON1) is a Ca(2+)-dependent serum enzyme and can hydrolyze (and inactivate) a wide range of substrates. It is a multifaceted enzyme and exhibit anti-inflammatory, anti-oxidative, anti-atherogenic, anti-diabetic, anti-microbial, and organophosphate (OP)-detoxifying properties. Thus, h-PON1 is a strong candidate for the development of therapeutic intervention against these conditions in humans. Insufficient hydrolyzing activity of native h-PON1 against desirable substrate affirms the urgent need to develop improved variant(s) of h-PON1 having enhanced activity. Production of recombinant h-PON1 (rh-PON1) using an Escherichia coli expression system is a key to develop such variant(s). However, generation of rh-PON1 using E. coli expression system has been elusive until now because of the aggregation of over-expressed rh-PON1 protein in inactive form as inclusion bodies (IBs) in the bacterial cells. In this study, we have over-expressed rh-PON1(wt) and rh-PON1(H115W;R192K) proteins as IBs in E. coli, and refolded the inactive enzymes present in the IBs to their active form using in vitro refolding. The active enzymes were isolated from the refolding mixture by ion-exchange chromatography. The catalytic properties of the refolded enzymes were similar to their soluble counterparts. Our results show that the pure and the active variant of rh-PON1 enzyme having enhanced hydrolyzing activity can be produced in large quantities using E. coli expression system. This method can be used for the industrial scale production of rh-PON1 enzymes and will aid in developing h-PON1 as a therapeutic candidate.

  16. Metabolic Profiles and Free Radical Scavenging Activity of Cordyceps bassiana Fruiting Bodies According to Developmental Stage

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    Hyun, Sun-Hee; Lee, Seok-Young; Sung, Gi-Ho; Kim, Seong Hwan; Choi, Hyung-Kyoon

    2013-01-01

    The metabolic profiles of Cordyceps bassiana according to fruiting body developmental stage were investigated using gas chromatography-mass spectrometry. We were able to detect 62 metabolites, including 48 metabolites from 70% methanol extracts and 14 metabolites from 100% n-hexane extracts. These metabolites were classified as alcohols, amino acids, organic acids, phosphoric acids, purine nucleosides and bases, sugars, saturated fatty acids, unsaturated fatty acids, or fatty amides. Significant changes in metabolite levels were found according to developmental stage. Relative levels of amino acids, purine nucleosides, and sugars were higher in development stage 3 than in the other stages. Among the amino acids, valine, isoleucine, lysine, histidine, glutamine, and aspartic acid, which are associated with ABC transporters and aminoacyl-tRNA biosynthesis, also showed higher levels in stage 3 samples. The free radical scavenging activities, which were significantly higher in stage 3 than in the other stages, showed a positive correlation with purine nucleoside metabolites such as adenosine, guanosine, and inosine. These results not only show metabolic profiles, but also suggest the metabolic pathways associated with fruiting body development stages in cultivated C. bassiana. PMID:24058459

  17. Metabolic profiles and free radical scavenging activity of Cordyceps bassiana fruiting bodies according to developmental stage.

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    Sun-Hee Hyun

    Full Text Available The metabolic profiles of Cordyceps bassiana according to fruiting body developmental stage were investigated using gas chromatography-mass spectrometry. We were able to detect 62 metabolites, including 48 metabolites from 70% methanol extracts and 14 metabolites from 100% n-hexane extracts. These metabolites were classified as alcohols, amino acids, organic acids, phosphoric acids, purine nucleosides and bases, sugars, saturated fatty acids, unsaturated fatty acids, or fatty amides. Significant changes in metabolite levels were found according to developmental stage. Relative levels of amino acids, purine nucleosides, and sugars were higher in development stage 3 than in the other stages. Among the amino acids, valine, isoleucine, lysine, histidine, glutamine, and aspartic acid, which are associated with ABC transporters and aminoacyl-tRNA biosynthesis, also showed higher levels in stage 3 samples. The free radical scavenging activities, which were significantly higher in stage 3 than in the other stages, showed a positive correlation with purine nucleoside metabolites such as adenosine, guanosine, and inosine. These results not only show metabolic profiles, but also suggest the metabolic pathways associated with fruiting body development stages in cultivated C. bassiana.

  18. Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

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    Rinas Ursula

    2004-09-01

    Full Text Available Abstract Recent advances in generating active proteins through refolding of bacterial inclusion body proteins are summarized in conjunction with a short overview on inclusion body isolation and solubilization procedures. In particular, the pros and cons of well-established robust refolding techniques such as direct dilution as well as less common ones such as diafiltration or chromatographic processes including size exclusion chromatography, matrix- or affinity-based techniques and hydrophobic interaction chromatography are discussed. Moreover, the effect of physical variables (temperature and pressure as well as the presence of buffer additives on the refolding process is elucidated. In particular, the impact of protein stabilizing or destabilizing low- and high-molecular weight additives as well as micellar and liposomal systems on protein refolding is illustrated. Also, techniques mimicking the principles encountered during in vivo folding such as processes based on natural and artificial chaperones and propeptide-assisted protein refolding are presented. Moreover, the special requirements for the generation of disulfide bonded proteins and the specific problems and solutions, which arise during process integration are discussed. Finally, the different strategies are examined regarding their applicability for large-scale production processes or high-throughput screening procedures.

  19. Comparison of body fat in Brazilian adult females by bioelectrical impedance analysis

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    Altamir, Vaz; Frère, Slaets Annie France; Ramírez Leonardo, López

    2012-12-01

    Body-fat is essential for human body, provided that its amount is at healthy levels. If in-excess body-fat is deleterious, its lack is otherwise also harmful. Estimated percent body-fat performed with commercially available devices measuring bioimpedance have many advantages, such as easy measurement and low cost. However, these measurements are based on standard models and equations that are not disclosed by manufacturers, and this leads to questioning the validity of these estimates for Brazilian females. The aim of this study was to compare electrical tetrapolar and octapolar impedance results obtained with commercially available equipment: Maltron BF-906 and OMRON 510-W. Data analysis involved descriptive and inferential statistics. Devices used in this study to estimate body fat quantity have not shown any significant differences in results; this is a major issue when selecting equipment based on three factors: study focus, available financial resources, and target population. Results obtained from the two devices have not shown any significant differences, which lead to the conclusion that either device may be reliably used.

  20. How close do we live to water? A global analysis of population distance to freshwater bodies.

    Science.gov (United States)

    Kummu, Matti; de Moel, Hans; Ward, Philip J; Varis, Olli

    2011-01-01

    Traditionally, people have inhabited places with ready access to fresh water. Today, over 50% of the global population lives in urban areas, and water can be directed via tens of kilometres of pipelines. Still, however, a large part of the world's population is directly dependent on access to natural freshwater sources. So how are inhabited places related to the location of freshwater bodies today? We present a high-resolution global analysis of how close present-day populations live to surface freshwater. We aim to increase the understanding of the relationship between inhabited places, distance to surface freshwater bodies, and climatic characteristics in different climate zones and administrative regions. Our results show that over 50% of the world's population lives closer than 3 km to a surface freshwater body, and only 10% of the population lives further than 10 km away. There are, however, remarkable differences between administrative regions and climatic zones. Populations in Australia, Asia, and Europe live closest to water. Although populations in arid zones live furthest away from freshwater bodies in absolute terms, relatively speaking they live closest to water considering the limited number of freshwater bodies in those areas. Population distributions in arid zones show statistically significant relationships with a combination of climatic factors and distance to water, whilst in other zones there is no statistically significant relationship with distance to water. Global studies on development and climate adaptation can benefit from an improved understanding of these relationships between human populations and the distance to fresh water.

  1. Using bench press load to predict upper body exercise loads in physically active individuals.

    Science.gov (United States)

    Wong, Del P; Ngo, Kwan-Lung; Tse, Michael A; Smith, Andrew W

    2013-01-01

    This study investigated whether loads for assistance exercises of the upper body can be predicted from the loads of the bench press exercise. Twenty-nine physically active collegiate students (age: 22.6 ± 2.5; weight training experience: 2.9 ± 2.1 years; estimated 1RM bench press: 54.31 ± 14.60 kg; 1RM: body weight ratio: 0.80 ± 0.22; BMI: 22.7 ± 2.1 kg·m(-2)) were recruited. The 6RM loads for bench press, barbell bicep curl, overhead dumbbell triceps extension, hammer curl and dumbbell shoulder press were measured. Test-retest reliability for the 5 exercises as determined by Pearson product moment correlation coefficient was very high to nearly perfect (0.82-0.98, p press load was significantly correlated with the loads of the 4 assistance exercises (r ranged from 0.80 to 0.93, p press load was a significant (R(2) range from 0.64 to 0.86, p press load (0.28) + 6.30 kg, (b) Barbell biceps curl = Bench press load (0.33) + 6.20 kg, (c) Overhead triceps extension = Bench press load (0.33) - 0.60 kg, and (d) Dumbbell shoulder press = Bench press load (0.42) + 5.84 kg. The difference between the actual load and the predicted load using the four equations ranged between 6.52% and 8.54%, such difference was not significant. Fitness professionals can use the 6RM bench press load as a time effective and accurate method to predict training loads for upper body assistance exercises. Key pointsThe bench press load was significantly correlated with the loads of the 4 assistance exercises.No significant differences were found between the actual load and the predicted load in the four equations.6RM bench press load can be a time effective and accurate method to predict training loads for upper body assistance exercises.

  2. Osteoblast activity on anodized titania nanotubes: effect of simulated body fluid soaking time.

    Science.gov (United States)

    Bayram, Cem; Demirbilek, Murat; Calişkan, Nazli; Demirbilek, Melike Erol; Denkbaş, Emir Baki

    2012-06-01

    Early phase osseointegration is crucial for orthopedic implants. For the improvement of osseointegrative properties of orthopedic implants several surface modification methods such as acid etching, hydroxyapatite (HA) coating and sandblasting can be applied. In this article titanium implants were anodized to possess nanotubular titania structures on the surface. Titania nanotube structures with a 45-50 nm of average inner diameter were obtained and to enhance bioactivity, samples were soaked in 10X simulated body fluid (SBF) for apatite deposition on surface for different time periods (1, 2, 3, 5, 8 hours). Apatitic calcium phosphate deposited surfaces were analyzed with infrared spectrometry and wettability studies. Effect of soaking time on osteoblast cell was investigated by cell viability, alkaline phosphatase activity tests and morphological evaluations. As a result, 3 hours of soaking time was found as the optimum time period (p anodized titanium implants however excess and/or uncontrolled HA coating of titania layer limits the bioactive potential of the implant.

  3. Antitumor and Antioxidant Activities of the Extracts from Fruiting Body of Phellinus linteus.

    Science.gov (United States)

    Lee, June Woo; Baek, Seong Jin; Bae, Woo Chul; Park, Jeong Min; Kim, Yong Seok

    2006-12-01

    Fruiting bodies of Phellinus linteus were extracted by hot water and alkali methods. Sugar contents of PL-H (hot water extract) and PL-A (alkali water extract) were 81.1%, 37.4% and protein contents were 6.2%, 21.8%, respectively. Amino acid pattern showed that two extracts contained large amount of aspartic acid and alanine. Two extracts showed characteristic IR absorption pattern for glycosidic bond at 890 cm(-1). PL-H was divided two fractions by gel filtration chromatography and the molecular weights of each fraction were estimated to be about 10 kD and 225 kD, respectively and also PL-A was estimated 10 kD. Two extracts showed strong antitumor, immunomodulating and antioxidant activities, and were compared with commercialized glycopeptide anticancer drugs.

  4. Effects of Mooring Systems on the Performance of a Wave Activated Body Energy Converter

    DEFF Research Database (Denmark)

    Zanuttigh, Barbara; Angelelli, Elisa; Kofoed, Jens Peter

    2013-01-01

    Aim of this paper is to analyse the power and hydraulic performance of a floating Wave Energy Converter with the purpose at optimising its design for installation in arrays. The paper presents new experiments carried out in 1:30 scale on a single device of the Wave Activated Body type in the deep......-water wave tank at Aalborg University. Power production and wave transmission were examined by changing the mooring system, the wave attack and the device orientation with respect to the incoming waves.. To assure the best performance the device size may be “tuned” based on the local peak wave length...... and the mooring system should be selected to allow the device for large movements....

  5. Experimental assessment of the mooring influence on the power output of floating Wave Activated Body WECs

    DEFF Research Database (Denmark)

    2013-01-01

    The paper presents the preliminary results of new physical tests carried out in the directional wave basin of Aalborg University (DK). The devices under exams are two floating 7 Degrees of Freedom Wave Activated Bodies moored with a spread system composed by 4 steel chains. The devices were subject...... to ordinary North Sea wave climate conditions and deployed in 1:60 scale. The main purpose of this paper is to analyse the performance of a Wave Energy Converter considering the interdependencies among energy production, loads on real moorings and device movements. The mooring effects on power production...... and on device movements are specifically investigated by varying the chain pre-tension level. Results suggest that the power production optimization is achieved with a slack mooring system providing a quasi-static response to the ordinary wave attacks...

  6. Pain in long-term breast cancer survivors: the role of body mass index, physical activity, and sedentary behavior.

    Science.gov (United States)

    Forsythe, Laura P; Alfano, Catherine M; George, Stephanie M; McTiernan, Anne; Baumgartner, Kathy B; Bernstein, Leslie; Ballard-Barbash, Rachel

    2013-01-01

    Although pain is common among post-treatment breast cancer survivors, studies that are longitudinal, identify a case definition of clinically meaningful pain, or examine factors contributing to pain in survivors are limited. This study describes longitudinal patterns of pain in long-term breast cancer survivors, evaluating associations of body mass index (BMI), physical activity, sedentary behavior with mean pain severity and above-average pain. Women newly diagnosed with stages 0-IIIA breast cancer (N = 1183) were assessed, on average, 6 months (demographic/clinical characteristics), 30 months (demographics), 40 months (demographics, pain), 5 years (BMI, physical activity, and sedentary behavior), and 10 years (demographics, pain, BMI, physical activity, and sedentary behavior) post-diagnosis. This analysis includes survivors who completed pain assessments 40 months post-diagnosis (N = 801), 10 years post-diagnosis (N = 563), or both (N = 522). Above-average pain was defined by SF-36 bodily pain scores ≥1/2 standard deviation worse than age-specific population norms. We used multiple regression models to test unique associations of BMI, physical activity, and sedentary behavior with pain adjusting for demographic and clinical factors. The proportion of survivors reporting above-average pain was higher at 10 years than at 40 months (32.3 vs. 27.8 %, p 5 %) was positively associated, while meeting physical activity guidelines was inversely associated, with above-average pain (OR, 95 % CI = 1.76, 1.03-3.01 and 0.40, 0.20-0.84, respectively) (p < 0.05). Weight gain and lack of physical activity place breast cancer survivors at risk for pain long after treatment ends. Weight control and exercise interventions should be tested for effects on long-term pain in these women.

  7. WISE/NEOWISE observations of Active Bodies in the Main Belt

    CERN Document Server

    Bauer, James M; Grav, Tommy; Walker, Russell G; Masiero, Joseph R; Blauvelt, Erin K; McMillan, Robert S; Fernández, Yan R; Meech, Karen J; Lisse, Carey M; Cutri, Roc M; Dailey, John W; Tholen, David J; Riesen, Timm; Urban, Laurie; Khayat, Alain; Pearman, George; Scotti, James V; Kramer, Emily; Cherry, De'Andre; Gautier, Thomas; Gomillion, Stephanie; Watkins, Jessica; Wright, Edward L

    2011-01-01

    We report results based on mid-infrared photometry of 5 active main belt objects (AMBOs) detected by the Wide-field Infrared Survey Explorer (WISE) spacecraft. Four of these bodies, P/2010 R2 (La Sagra), 133P/Elst-Pizarro, (596) Scheila, and 176P/LINEAR, showed no signs of activity at the time of the observations, allowing the WISE detections to place firm constraints on their diameters and albedos. Geometric albedos were in the range of a few percent, and on the order of other measured comet nuclei. P/2010 A2 was observed on April 2-3, 2010, three months after its peak activity. Photometry of the coma at 12 and 22 {\\mu}m combined with ground-based visible-wavelength measurements provides constraints on the dust particle mass distribution (PMD), dlogn/dlogm, yielding power-law slope values of {\\alpha} = -0.5 +/- 0.1. This PMD is considerably more shallow than that found for other comets, in particular inbound particle fluence during the Stardust encounter of comet 81P/Wild 2. It is similar to the PMD seen for...

  8. WISE/NEOWISE OBSERVATIONS OF ACTIVE BODIES IN THE MAIN BELT

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, James M.; Mainzer, A. K.; Masiero, Joseph R.; Blauvelt, Erin K.; Cherry, De' Andre [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, MS 183-401, Pasadena, CA 91109 (United States); Grav, Tommy [Planetary Science Institute, 1700 East Fort Lowell, Suite 106, Tucson, AZ 85719-2395 (United States); Walker, Russell G. [Monterey Institute for Research in Astronomy, 200 Eighth Street, Marina, CA 93933 (United States); McMillan, Robert S.; Scotti, James V. [Lunar and Planetary Laboratory, University of Arizona, 1629 East University Boulevard, Kuiper Space Science Building 92, Tucson, AZ 85721-0092 (United States); Fernandez, Yan R.; Kramer, Emily [Department of Physics, University of Central Florida, 4000 Central Florida Boulevard, P.S. Building, Orlando, FL 32816-2385 (United States); Meech, Karen J.; Tholen, David J.; Riesen, Timm; Urban, Laurie; Khayat, Alain [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Manoa, HI 96822 (United States); Lisse, Carey M. [Applied Physics Laboratory, Johns Hopkins University, 11100 Johns Hopkins Road, Laurel, MD 20723-6099 (United States); Cutri, Roc M.; Dailey, John W.; Pearman, George, E-mail: bauer@scn.jpl.nasa.gov [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Collaboration: WISE Team; and others

    2012-03-01

    We report results based on mid-infrared photometry of five active main belt objects (AMBOs) detected by the Wide-field Infrared Survey Explorer (WISE) spacecraft. Four of these bodies, P/2010 R2 (La Sagra), 133P/Elst-Pizarro, (596) Scheila, and 176P/LINEAR, showed no signs of activity at the time of the observations, allowing the WISE detections to place firm constraints on their diameters and albedos. Geometric albedos were in the range of a few percent, and on the order of other measured comet nuclei. P/2010 A2 was observed on 2010 April 2-3, three months after its peak activity. Photometry of the coma at 12 and 22 {mu}m combined with ground-based visible-wavelength measurements provides constraints on the dust particle mass distribution (PMD), dlog n/dlog m, yielding power-law slope values of {alpha} = -0.5 {+-} 0.1. This PMD is considerably more shallow than that found for other comets, in particular inbound particle fluence during the Stardust encounter of comet 81P/Wild 2. It is similar to the PMD seen for 9P/Tempel 1 in the immediate aftermath of the Deep Impact experiment. Upper limits for CO{sub 2} and CO production are also provided for each AMBO and compared with revised production numbers for WISE observations of 103P/Hartley 2.

  9. Analysis of the reverse recovery oscillation of superjunction MOSFET body diode

    Science.gov (United States)

    Xue, Peng; Fu, Guicui

    2017-03-01

    The voltage and current oscillations occasionally occur during the reverse recovery transient of the superjunction MOSFET body diode. This paper identifies the unique reverse recovery oscillation characteristics of the superjunction MOSFET body diode. Base on the experimental investigation and theoretical analysis, the various reverse recovery oscillation mechanisms are clarified. At first, with a discrete 650 V/47 A superjunction MOSFET utilized, the high-frequency and low-frequency oscillation characteristics during the reverse recovery transient are obtained by the double-pulse test. After the theoretical analysis, it is found that the superjunction MOSFET body diode has various oscillation mechanisms depending on its drift region injection level. Under high-level injection condition, the high-frequency oscillation occurs due to the plasma extraction transient-time (PETT) effect. Under low-level injection condition, the body diode's snappy reverse recovery results in the low-frequency LC oscillation. In the end of the paper, the oscillation behaviors under both high and low level injection conditions are reproduced by the mixed-mode numerical simulation, the simulation results validate the proposed oscillation mechanisms.

  10. Effects of Dietary Carbohydrate-lipid Ratio on Growth, Body Composition and Digestive Enzyme Activities of Juvenile Peanut Worm,Sipunculus nudus

    Institute of Scientific and Technical Information of China (English)

    Zhang; Qin; Xu; Mingzhu; Tong; Tong; Tong; Wanping; Dong; Lanfang; Cheng; Guangping; Zou; Jie; Jiang; Yan

    2014-01-01

    [Objective] This study was conducted to investigate the effects of dietary carbohydrate-lipid( C / L) ratios on growth performance,body composition and digestive enzyme activities of juvenile peanut worm. [Methods]Juvenile peanut worm with average body weight of( 16. 77 ± 0. 40) mg were fed with five isonitrogenous and isoenergetic diets formulated to contain different carbohydrate / lipid( C / L) ratios( 0. 68,1. 02,1. 62,2. 61 or 4. 35) for 8 weeks. [Results] The dietary C / L ratios had no significant effects on survival of juvenile peanut worm( P > 0. 05). With the increasing of dietary C / L ratios,weight growth rate( WGR)and specific growth rate( SGR) increased when dietary C / L ratios were between 0. 68 and 2. 61,and then decreased significantly with dietary C / L ratio further increased. When the dietary C / L ratio was 2. 61( carbohydrate level was 20. 64%,lipid level was 7. 92%) both WGR and SGR produced the maximum value,they were 451. 78 ± 16. 85% and 3. 41 ± 0. 06 % / d,respectively. The dietary C / L ratios had significant effects on body moisture,body protein content and body lipid content( P < 0. 05),but no significant effects on body ash content of juvenile peanut worm( P > 0. 05). Different C / L ratios had significant effects on amylase activity and lipases activity of juvenile peanut worm( P < 0. 05),but no significant effects on protease activity( P > 0. 05). [Conclusion]The regression model analysis showed that the most suitable dietary C / L ratio which can make juvenile peanut worm acquire the best weight growth rate is 2. 42.

  11. Metabolic features of Protochlamydia amoebophila elementary bodies--a link between activity and infectivity in Chlamydiae.

    Directory of Open Access Journals (Sweden)

    Barbara S Sixt

    Full Text Available The Chlamydiae are a highly successful group of obligate intracellular bacteria, whose members are remarkably diverse, ranging from major pathogens of humans and animals to symbionts of ubiquitous protozoa. While their infective developmental stage, the elementary body (EB, has long been accepted to be completely metabolically inert, it has recently been shown to sustain some activities, including uptake of amino acids and protein biosynthesis. In the current study, we performed an in-depth characterization of the metabolic capabilities of EBs of the amoeba symbiont Protochlamydia amoebophila. A combined metabolomics approach, including fluorescence microscopy-based assays, isotope-ratio mass spectrometry (IRMS, ion cyclotron resonance Fourier transform mass spectrometry (ICR/FT-MS, and ultra-performance liquid chromatography mass spectrometry (UPLC-MS was conducted, with a particular focus on the central carbon metabolism. In addition, the effect of nutrient deprivation on chlamydial infectivity was analyzed. Our investigations revealed that host-free P. amoebophila EBs maintain respiratory activity and metabolize D-glucose, including substrate uptake as well as host-free synthesis of labeled metabolites and release of labeled CO2 from (13C-labeled D-glucose. The pentose phosphate pathway was identified as major route of D-glucose catabolism and host-independent activity of the tricarboxylic acid (TCA cycle was observed. Our data strongly suggest anabolic reactions in P. amoebophila EBs and demonstrate that under the applied conditions D-glucose availability is essential to sustain metabolic activity. Replacement of this substrate by L-glucose, a non-metabolizable sugar, led to a rapid decline in the number of infectious particles. Likewise, infectivity of Chlamydia trachomatis, a major human pathogen, also declined more rapidly in the absence of nutrients. Collectively, these findings demonstrate that D-glucose is utilized by P. amoebophila

  12. A novel ribonuclease with antiproliferative activity from fresh fruiting bodies of the edible mushroom Hypsizigus marmoreus.

    Science.gov (United States)

    Guan, G P; Wang, H X; Ng, T B

    2007-12-01

    An 18-kDa ribonuclease (RNase) with a novel N-terminal sequence was purified from fresh fruiting bodies of the mushroom Hypsizigus marmoreus. The purification protocol comprised ion exchange chromatography on DEAE cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose and Q-Sepharose and gel filtration by fast protein liquid chromatography on Superdex 75. The starting buffer was 10 mM Tris-HCl buffer (pH 7.2), 10 mM Tris-HCl buffer (pH 7.2), 10 mM NH(4)OAc buffer (pH 5), 10 mM NH(4)HCO(3) buffer (pH 9.4) and 200 mM NH(4)HCO(3) (pH 8.5), respectively. Absorbed proteins were desorbed using NaCl added to the starting buffer. A 42-fold purification of the enzyme was achieved. The RNase was unadsorbed on DEAE cellulose, Affi-gel blue gel and CM-cellulose but adsorbed on Q-Sepharose. It exhibited maximal RNase activity at pH 5 and 70 degrees C. Some RNase activity was detectable at 100 degrees C. It demonstrated the highest ribonucleolytic activity (196 U/mg) toward poly C, the next highest activity (126 U/mg) toward poly A, and much weaker activity toward poly U (48 U/mg) and poly G (41 U/mg). The RNase inhibited [(3)H-methyl]-thymidine uptake by leukemia L1210 cells with an IC(50) of 60 microM.

  13. Activation analysis of meteorites. 3

    Energy Technology Data Exchange (ETDEWEB)

    Nagai, H.; Honda, M.; Sato, H. [Nihon Univ., College of Humanities and Sciences, Tokyo (Japan); Ebihara, M.; Oura, Y.; Setoguchi, M. [Tokyo Metropolitan Univ., Faculty of Science, Tokyo (Japan)

    2001-07-01

    A long-lived cosmogenic nuclide, {sup 53}Mn in extra-terrestrial materials has been determined in the DR-1 hole of the JRR-3M reactor, applying the well-thermalized neutron flux. The neutron flux intensities are variable with the depths whereas the fast thermal ratios are not quite variable. By this method, {sup 53}Mn contents in iron meteorites and metal phases in general could be routinely determined in many samples. The chemical separation method has been modified and a convenient short circuit method has been proposed to shorten the process. The short method is to count the activities of {sup 54}Mn just after the irradiation without further purification of manganese. (author)

  14. Correlation between percentage of body fat measured by the Slaughter equation and bio impedance analysis technique in Mexican schoolchildren

    Directory of Open Access Journals (Sweden)

    Mariana Orta Duarte

    2014-01-01

    Full Text Available Introduction: Obesity is considered one of the most serious public health problems of the 21st century in children and adolescents. The percentile or Z-score of the body mass index is widely used in children and adolescents to define and assess overweight and obesity, but it does not determine the percentage of total body fat. Other anthropometric measurements that determine total body fat are skinfold thickness and methods of body composition assessment such as bio impedance analysis, both of which are rapid and inexpensive. Objetive: The aim of the study was to correlate the percentage of body fat determined by the Slaughter equation with the percentage of body fat determined by the bio impedance analysis technique, and the body mass index in schoolchildren. Methods: The design of the study is cross-sectional and it was performed on a random selection of 74 children (9.47 ± 1.55 years old attending a primary school in Colima, Mexico during 2011. The percentage of body fat was measured by the Slaughter equation and bio impedance analysis technique. Body mass index was calculated. Inferential statistics were performed with the non-paired Student's t test, Pearson's correlation for quantitative variables (percentage of body fat by the Slaughter equation and bio impedance analysis and the Fisher exact test for qualitative variables. Results: A significant correlation (r = 0.74; p < 0.001 was identified between the percentage of fat measured by the Slaughter equation and bio impedance analysis. We also identified a significant correlation between the percentage of fat measured by the Slaughter equation and body mass index (r = 0. 85; p < 0.001 and the percentage of fat measured by bio impedance analysis and body mass index (r = 0.78; p < 0.001. Conclusion: Given that we identified a significant positive correlation between BIA and STE, we conclude that both are adequate alternatives for measuring the percentage of body fat among schoolchildren in

  15. Effect of physical activity on body mineral density%运动对骨密度的影响分析

    Institute of Scientific and Technical Information of China (English)

    黄雅雯

    2012-01-01

    目的 研究运动对身体成分和骨密度的影响.方法 随机选取体育专业并有规律运动学生100名为运动组,非体育专业并无规律运动学生100名为对照组,检测研究对象身体成分和量密度相关指标值.结果 性别和运动分别是影响BMI、体脂百分比、腰臀比、骨强度值、T值和Z值的因素.并且运动对体脂百分比和骨密度各指标影响有显著性差异(P<0.05).结论 有规律的运动对人体骨密度有一定的影响,并起到积极作用.%Objective To study on the effect of physical activity on body content and body mineral density. Methods We randomly selected 100 students with physical activity as sports group, and 100 students without physical activity as controls, and their body content and body mineral density were detected. Results Sex and physical activity are the influencing factors for the BMI, body fat, WHR, bone strength value, T value and Z value. Physical activity had significantly influencing on the body fat and bone strength(P<0.05). Conclusion Sports activity had a certain effect on the body mineral density and play an activity role on it.

  16. [Analysis of body mass index in different sector workers for over ten years].

    Science.gov (United States)

    Perbellini, L; Zonzin, C; Baldo, M

    2010-01-01

    A critical review of the literature on obesity and overweight underlines that a low educational level, a low social-economic status, certain working conditions, the lack of physical activity in leisure time, together with the availability of food, are the main factors favouring increased prevalence of obesity. Certain jobs also contribute significantly to this problem. Automation, the use of machines for heavy works and sedentary activities favour body weight increase. Jobs that are a source of stress, such as work with night shift can cause metabolic disorders leading to an increased prevalence of obesity. The main aim of this article is to study the trend of body weight in different working area during ten years, comparing this parameter to different factors such as job, blood pressure, smoke, alcool and health diseases.

  17. Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity.

    Science.gov (United States)

    Suh, Wonse; Nam, Gyeongsug; Yang, Woo Seok; Sung, Gi-Ho; Shim, Sang Hee; Cho, Jae Youl

    2017-03-01

    Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by NF-κB and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor (TNF)-α. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.

  18. The study of external dose rate and retained body activity of patients receiving 131I therapy for differentiated thyroid carcinoma.

    Science.gov (United States)

    Zhang, Haiying; Jiao, Ling; Cui, Songye; Wang, Liang; Tan, Jian; Zhang, Guizhi; He, Yajing; Ruan, Shuzhou; Fan, Saijun; Zhang, Wenyi

    2014-10-21

    Radiation safety is an integral part of targeted radionuclide therapy. The aim of this work was to study the external dose rate and retained body activity as functions of time in differentiated thyroid carcinoma patients receiving 131I therapy. Seventy patients were stratified into two groups: the ablation group (A) and the follow-up group (FU). The patients' external dose rate was measured, and simultaneously, their retained body radiation activity was monitored at various time points. The equations of the external dose rate and the retained body activity, described as a function of hours post administration, were fitted. Additionally, the release time for patients was calculated. The reduction in activity in the group receiving a second or subsequent treatment was more rapid than the group receiving only the initial treatment. Most important, an expeditious method was established to indirectly evaluate the retained body activity of patients by measuring the external dose rate with a portable radiation survey meter. By this method, the calculated external dose rate limits are 19.2, 8.85, 5.08 and 2.32 μSv·h-1 at 1, 1.5, 2 and 3 m, respectively, according to a patient's released threshold level of retained body activity <400 MBq. This study is beneficial for radiation safety decision-making.

  19. The Study of External Dose Rate and Retained Body Activity of Patients Receiving 131I Therapy for Differentiated Thyroid Carcinoma

    Directory of Open Access Journals (Sweden)

    Haiying Zhang

    2014-10-01

    Full Text Available Radiation safety is an integral part of targeted radionuclide therapy. The aim of this work was to study the external dose rate and retained body activity as functions of time in differentiated thyroid carcinoma patients receiving 131I therapy. Seventy patients were stratified into two groups: the ablation group (A and the follow-up group (FU. The patients’ external dose rate was measured, and simultaneously, their retained body radiation activity was monitored at various time points. The equations of the external dose rate and the retained body activity, described as a function of hours post administration, were fitted. Additionally, the release time for patients was calculated. The reduction in activity in the group receiving a second or subsequent treatment was more rapid than the group receiving only the initial treatment. Most important, an expeditious method was established to indirectly evaluate the retained body activity of patients by measuring the external dose rate with a portable radiation survey meter. By this method, the calculated external dose rate limits are 19.2, 8.85, 5.08 and 2.32 μSv·h−1 at 1, 1.5, 2 and 3 m, respectively, according to a patient’s released threshold level of retained body activity <400 MBq. This study is beneficial for radiation safety decision-making.

  20. Self-Objectification and the Use of Body Image Coping Strategies: The Role of Shame in Highly Physically Active Women.

    Science.gov (United States)

    Bailey, K Alysse; Lamarche, Larkin; Gammage, Kimberley L; Sullivan, Philip J

    2016-01-01

    We investigated the mediating role of body shame in the relationship between self-objectification and body image coping strategies in highly physically active university women. Bivariate correlations revealed body shame was positively related to self-objectification, appearance fixing, and avoidance coping but unrelated to positive rational acceptance. In addition, self-objectification was positively related to appearance fixing and avoidance coping but unrelated to positive rational acceptance. Mediation analyses showed that body shame partially mediated the relationship between self-objectification and avoidance and appearance fixing coping but did not mediate the relationship between self-objectification and positive rational acceptance. Future research should examine other potential mediators or moderators in this relationship and explore the role of positive body image framed within self-objectification theory.

  1. Effects of Resveratrol on Daily Rhythms of Locomotor Activity and Body Temperature in Young and Aged Grey Mouse Lemurs

    Directory of Open Access Journals (Sweden)

    Fabien Pifferi

    2013-01-01

    Full Text Available In several species, resveratrol, a polyphenolic compound, activates sirtuin proteins implicated in the regulation of energy balance and biological clock processes. To demonstrate the effect of resveratrol on clock function in an aged primate, young and aged mouse lemurs (Microcebus murinus were studied over a 4-week dietary supplementation with resveratrol. Spontaneous locomotor activity and daily variations in body temperature were continuously recorded. Reduction in locomotor activity onset and changes in body temperature rhythm in resveratrol-supplemented aged animals suggest an improved synchronisation on the light-dark cycle. Resveratrol could be a good candidate to restore the circadian rhythms in the elderly.

  2. Analysis of annual exposure of private farmers to noise and whole body vibration

    OpenAIRE

    2012-01-01

    Based on a literature review for the period of 1982– 2011, an analysis was performed of studies by various researchers concerning the exposure of private farmers to noise and vibration of the whole body with particular consideration of the annual exposure to these factors. The main sources of noise occurring in agriculture are: agricultural tractors mounted with a set of farm machinery, self-propelled machines, machinery for the production of fodder and workshop equipm...

  3. Infants' Emerging Sensitivity to Emotional Body Expressions: Insights from Asymmetrical Frontal Brain Activity

    Science.gov (United States)

    Missana, Manuela; Grossmann, Tobias

    2015-01-01

    Sensitive responding to others' emotional body expressions is an essential social skill in humans. Using event-related brain potentials, it has recently been shown that the ability to discriminate between emotional body expressions develops between 4 and 8 months of age. However, it is not clear whether the perception of emotional body expressions…

  4. The effects of feed restriction on physical activity, body weight, physiology, haematology and immunology in female mink

    DEFF Research Database (Denmark)

    Damgaard, Birthe Marie; Dalgaard, Tina Sørensen; Larsen, Torben;

    2012-01-01

    The aim of the present study was to investigate if adult mink females characterised as having a high or low residual feed intake (RFI) differed in their response to feed restriction with regard to activity, body weight loss and physiological parameters. For RFI-High, the activity was higher prior...

  5. The Influence of Whole-Body Vibration on Creatine Kinase Activity and Jumping Performance in Young Basketball Players

    Science.gov (United States)

    Fachina, Rafael; da Silva, Antônio; Falcão, William; Montagner, Paulo; Borin, João; Minozzo, Fábio; Falcão, Diego; Vancini, Rodrigo; Poston, Brach; de Lira, Claudio

    2013-01-01

    Purpose: To quantify creatine kinase (CK) activity changes across time following an acute bout of whole-body vibration (WBV) and determine the association between changes in CK activity and jumping performance. Method: Twenty-six elite young basketball players were assigned to 3 groups: 36-Hz and 46-Hz vibration groups (G36 and G46, respectively)…

  6. Effect of Physically Active Academic Lessons on Body Mass Index and Physical Fitness in Primary School Children

    Science.gov (United States)

    de Greeff, Johannes W.; Hartman, Esther; Mullender-Wijnsma, Marijke J.; Bosker, Roel J.; Doolaard, Simone; Visscher, Chris

    2016-01-01

    Background: Preventing overweight and improving physical fitness in primary school children is a worldwide challenge, and physically active intervention programs usually come with the cost of academic instruction time. This study aimed to investigate effects of physically active academic lessons on body mass index (BMI) and physical fitness in…

  7. Effect of change in physical activity on body fatness over a 10-y period in the Doetinchem Cohort Study

    NARCIS (Netherlands)

    May, Anne M.; Bueno-de-Mesquita, H. Bas; Boshuizen, Hendrick; Spijkerman, Annemieke M. W.; Peeters, Petra H. M.; Verschuren, W. M. Monique

    2010-01-01

    Background: Obesity is related to many adverse health-related outcomes. Objective: We investigated whether changes in physical activity were related to less gain in either body weight or waist circumference (WC). Design: The association between prospectively assessed physical activity and either bod

  8. Neutron Activation Analysis of Water - A Review

    Science.gov (United States)

    Buchanan, John D.

    1971-01-01

    Recent developments in this field are emphasized. After a brief review of basic principles, topics discussed include sources of neutrons, pre-irradiation physical and chemical treatment of samples, neutron capture and gamma-ray analysis, and selected applications. Applications of neutron activation analysis of water have increased rapidly within the last few years and may be expected to increase in the future.

  9. CHANGING TRENDS IN LIFESTYLE BEHAVIOUR AND PHYSICAL ACTIVITY ON BODY MASS INDEX AMONG MEDICAL STUDENTS

    Directory of Open Access Journals (Sweden)

    Viji

    2016-03-01

    Full Text Available BACKGROUND Early sleep, early waking up, regular breakfast and light-to-moderate exercise all constitute healthy habits. Balanced diet, regular sleep and adequate physical activity are major factors in the promotion and maintenance of good health in human life. Regrettably these habits are not very frequent among medical students, because of exceptionally tiring schedule, protracted studies and burden of performing well in medical colleges. The study aims to correlate the trends in breakfast habits, mid-day snacking, sleeping habits and physical activity in relation to body mass index among medical students. METHOD This was a single centre cross-sectional questionnaire based study conducted at Jubilee Mission Medical College & Research Institute, Thrissur, Kerala. The target population was 1 st year MBBS students. We collected data from 234 students. The study duration was from August 2014 till September 2015. Convenient sampling was implied for the collection of data. RESULTS Mean age of participants was 20.85 ± 0.9 years, while mean BMI of participants was 24.7 ± 6.31 kg/m2. Average sleep duration was 7.1 hours ± 3.9 hours while average physical activity was 208 min/week ± 92 min/week. We observed that females (63.4% tend to skip breakfast twice more than males (27.9%. Students who had regular breakfast were found to have a lower BMI than those who did not. Moreover, those who took breakfast were found to be more physically active than those who skipped breakfast. CONCLUSION Since it was found that a regular consumption of breakfast, adequate sleep and exercise not only lowers BMI but also makes a person more physically fit. Therefore, it is recommended to start the day with a healthy breakfast having all the essential nutrients.

  10. The impact of adolescent girls' life concerns and leisure activities on body dissatisfaction, disordered eating, and self-esteem.

    Science.gov (United States)

    Tiggemann, M

    2001-06-01

    The aim of this study was to situate adolescent girls' body dissatisfaction, disordered eating, and self-esteem in the context of their life concerns and leisure activities. Questionnaires containing measures of life concerns, leisure activities, body dissatisfaction, disordered eating, and self-esteem were administered to 306 girls with a mean age of 16 years. It was found that although academic success and intelligence were rated as the most important life concerns, an emphasis on slimness was most strongly linked to body dissatisfaction, disordered eating, and global self-esteem. An emphasis on popularity with girls also was related to body dissatisfaction, and hours spent watching television were related to lower self-esteem. In contrast, emphasis on sport seemed to serve a protective function. It was concluded that adolescent girls who have a high concern for slimness should be assisted in decreasing this emphasis in order to improve their general well-being.

  11. Effects of meal frequency on weight loss and body composition: a meta-analysis.

    Science.gov (United States)

    Schoenfeld, Brad Jon; Aragon, Alan Albert; Krieger, James W

    2015-02-01

    It has been hypothesized that eating small, frequent meals enhances fat loss and helps to achieve better weight maintenance. Several observational studies lend support to this hypothesis, with an inverse relationship noted between the frequency of eating and adiposity. The purpose of this narrative review is to present and discuss a meta-analysis with regression that evaluated experimental research on meal frequency with respect to changes in fat mass and lean mass. A total of 15 studies were identified that investigated meal frequency in accordance with the criteria outlined. Feeding frequency was positively associated with reductions in fat mass and body fat percentage as well as an increase in fat-free mass. However, sensitivity analysis of the data showed that the positive findings were the product of a single study, casting doubt as to whether more frequent meals confer beneficial effects on body composition. In conclusion, although the initial results of this meta-analysis suggest a potential benefit of increased feeding frequencies for enhancing body composition, these findings need to be interpreted with circumspection.

  12. Analysis of body composition of the abdomen at the level of the 4th lumbar vertebral body by CT

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, Tetsujiro

    1988-10-01

    Body composition of the area at the level of the 4th lumbar vertebral section was studied on X-ray CT images in 62 normal volunteers (32 men and 30 women ), whose ages ranged from 20 and 79 years. The total cross-sectional area was smallest in persons in their twenties, irrespecstive of sex, and began to increase after the age of 30. The abdominal cavity and muscles had the highest cross-sectional ratio (34%) to the total body, followed by subcutaneous fat in men. In women, the subcutaneous fat and abdominal cavity had a ratio of 34% to the total body. According to age groups, men in their twenties and thirties had the highest ratio of the muscle to the total body, followed by that of abdominal cavity and subcutaneous fat. In the group older than 40, the ratio of organs to the total body was as follows: the abdominal cavity>muscle>subcutaneous fat. Since the age of 70, each ratio of the muscle or subcutaneous fat to the total body was the same. Women between their twenties and fifties had the highest ratio of subcutaneous fat to the total body. Since the age of 60, the ratio of the abdominal cavity became highest. The subcutaneous fat and abdominal cavity tended to increase with aging; and the muscles tended to decrease. The real area of the vertebra increased slightly, but the vertebral foramen tended to decrease with aging. In men, mean areas of the muscles were as follows: abdominis lateralis>erector spinae>psoas major>quadratus lumborum and transversospinalis>rectus abdominis muscle. The same tendency was observed for women, except for the quadratus lumborum and rectus abdominis muscle. According to Rohrer index, the real areas of all components except the vertebral foramen tended to increase in the order of types A, C, and D in men. In women, the real area of the subcutaneous fat increased as well in the order of types A, C, and D. (Namekawa, K).

  13. Handling and storage of human body fluids for analysis of extracellular vesicles

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    Yuana Yuana

    2015-11-01

    Full Text Available Because procedures of handling and storage of body fluids affect numbers and composition of extracellular vesicles (EVs, standardization is important to ensure reliable and comparable measurements of EVs in a clinical environment. We aimed to develop standard protocols for handling and storage of human body fluids for EV analysis. Conditions such as centrifugation, single freeze–thaw cycle, effect of time delay between blood collection and plasma preparation and storage were investigated. Plasma is the most commonly studied body fluid in EV research. We mainly focused on EVs originating from platelets and erythrocytes and investigated the behaviour of these 2 types of EVs independently as well as in plasma samples of healthy subjects. EVs in urine and saliva were also studied for comparison. All samples were analysed simultaneously before and after freeze–thawing by resistive pulse sensing, nanoparticle tracking analysis, conventional flow cytometry (FCM and transmission (scanning electron microscopy. Our main finding is that the effect of centrifugation markedly depends on the cellular origin of EVs. Whereas erythrocyte EVs remain present as single EVs after centrifugation, platelet EVs form aggregates, which affect their measured concentration in plasma. Single erythrocyte and platelet EVs are present mainly in the range of 100–200 nm, far below the lower limit of what can be measured by conventional FCM. Furthermore, the effects of single freeze–thaw cycle, time delay between blood collection and plasma preparation up to 1 hour and storage up to 1 year are insignificant (p>0.05 on the measured concentration and diameter of EVs from erythrocyte and platelet concentrates and EVs in plasma, urine and saliva. In conclusion, in standard protocols for EV studies, centrifugation to isolate EVs from collected body fluids should be avoided. Freezing and storage of collected body fluids, albeit their insignificant effects, should be performed

  14. Impact of genetic strain on body fat loss, food consumption, metabolism, ventilation, and motor activity in free running female rats

    Science.gov (United States)

    Nuclear magnetic resonance (NMR) based body composition analysis is an idea means of assessing changes in relative proportions of fat, lean, and fluid in rodents non­ invasively. While the data are not as accurate as convent ional chemical analysis, the systems allow one to follo...

  15. The role of the media in body image concerns among women: a meta-analysis of experimental and correlational studies.

    Science.gov (United States)

    Grabe, Shelly; Ward, L Monique; Hyde, Janet Shibley

    2008-05-01

    Research suggests that exposure to mass media depicting the thin-ideal body may be linked to body image disturbance in women. This meta-analysis examined experimental and correlational studies testing the links between media exposure to women's body dissatisfaction, internalization of the thin ideal, and eating behaviors and beliefs with a sample of 77 studies that yielded 141 effect sizes. The mean effect sizes were small to moderate (ds = -.28, -.39, and -.30, respectively). Effects for some outcome variables were moderated by publication year and study design. The findings support the notion that exposure to media images depicting the thin-ideal body is related to body image concerns for women.

  16. Growth activity of epidermal cells from different parts of human body

    Institute of Scientific and Technical Information of China (English)

    CHAI Jia-ke; SHENG Zhi-yong; MA Zhong-feng; YANG Hong-ming; LIU Qiang; Liang Li-ming

    2007-01-01

    Background Most epidermal cells used in skin tissue engineering are obtained from the skins of fetuses or prepuces,which can not be widely used in culturing and transplanting autologous epidermis for patients with extensive burn wounds. To solve the problem, in this study, we cultured epidermal cells from different parts of human body in vitro, and detected their growth activity.Methods Normal epidermal cells obtained from the prepuce, scalp, and axilla of male patients, were cultured and passaged. Their growth characteristics including adherent rate and growth activity were compared. Data were analyzed by homogeneity test of variance.Results In primary culture, the growth of epidermal cells from the prepuce was significantly faster than that of the epidermal cells from the scalp and axilla. In the cells obtained from the prepuce, 80% confluence was achieved on day 12, while on day 16 and day 20 in the cells from the scalp and axilla, respectively. However, no significant difference was detected in their growth and proliferation in the second passage.Conclusions Although the growth of epidermal cells obtained from the scalp and axilla is slower than that from the prepuce in primary culture, stable cell line can be established and used in preparation of auto-epidermal grafts for patients with extensive burn wounds. Therefore, the scalp and axillary skin should be considered as important sources of epidermal cells other than the prepuce.

  17. Whole body muscle activity during the FIFA 11+ program evaluated by positron emission tomography.

    Directory of Open Access Journals (Sweden)

    Junsuke Nakase

    Full Text Available PURPOSE: This study investigated the effect of the FIFA 11+ warm-up program on whole body muscle activity using positron emission tomography. METHODS: Ten healthy male volunteers were divided into a control group and a group that performed injury prevention exercises (The 11+. The subjects of the control group were placed in a sitting position for 20 min and 37 MBq of (18F-fluorodeoxyglucose (FDG was injected intravenously. The subjects then remained seated for 45 min. The subjects of the exercise group performed part 2 of the 11+for 20 min, after which FDG was injected. They then performed part 2 of the 11+for 20 min, and rested for 25 min in a sitting position. Positron emission tomography-computed tomography images were obtained 50 min after FDG injection in each group. Regions of interest were defined within 30 muscles. The standardized uptake value was calculated to examine the FDG uptake of muscle tissue per unit volume. RESULTS: FDG accumulation within the abdominal rectus, gluteus medius and minimus were significantly higher in the exercise group than in the control group (P<0.05. CONCLUSION: The hip abductor muscles and abdominal rectus were active during part 2 of the FIFA 11+ program.

  18. Lumbar back muscle activity of helicopter pilots and whole-body vibration.

    Science.gov (United States)

    de Oliveira, C G; Simpson, D M; Nadal, J

    2001-10-01

    Several studies have attributed the prevalence of low back pain (LBP) in helicopter pilots mainly to poor posture in-flight and whole-body vibration, with the latter hypothesis particularly related to a cyclic response of the erector spine (ES) muscle to vibration. This work aims to determine if helicopter vibration and the pilot's normal posture during flight have significant effects on the electromyogram (EMG) of the ES muscle. The bilateral surface EMG of the ES muscle at the L3 level was collected in 10 young pilots before and during a short flight in UH-50 helicopters. The vibration was monitored by a triaxial accelerometer fixed to the pilots' seat. Prior to the flight, the EMG was recorded for relaxed seated and standing postures with 0 degrees (P0) and 35 degrees (P35) of trunk flexion. The effect of the posture during the flight was tested by comparing left and right EMG (normalized with respect to P35). The in-flight muscle stress was evaluated by histograms of EMG activity, and compared to P0 values. Only one pilot in ten showed significant (pvibration and the EMG over cycles of vibration, and no consistent causal effect was found. The pilots' posture did not show significant asymmetric muscular activity, and low EMG levels were observed during most of the duration of the flight. The results do not provide evidence that LBP in helicopter pilots is caused by ES muscle stress in the conditions studied.

  19. Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

    2016-01-01

    This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

  20. The Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor Gamma Gene Modifies the Association of Physical Activity and Body Mass Changes in Polish Women

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    Aleksandra Zarebska

    2014-01-01

    Full Text Available Peroxisome proliferator-activated receptor γ is a key regulator of adipogenesis, responsible for fatty acid storage and maintaining energy balance in the human body. Studies on the functional importance of the PPARG Pro12Ala polymorphic variants indicated that the observed alleles may influence body mass measurements; however, obtained results were inconsistent. We have decided to check if body mass changes observed in physically active participants will be modulated by the PPARG Pro12Ala genotype. The genotype distribution of the PPARG Pro12Ala allele was examined in a group of 201 Polish women measured for selected body mass variables before and after the completion of a 12-week training program. The results of our experiment suggest that PPARG genotype can modulate training-induced body mass measurements changes: after completion of the training program, Pro12/Pro12 homozygotes were characterised by a greater decrease of body fat mass measurements in comparison with 12Ala allele carriers. These results indicate that the PPARG 12Ala variant may impair the training-induced positive effects on body mass measurements; however, the detailed mechanism of such interaction remained unclear and observed correlation between PPARG genotype and body mass differential effects should be interpreted with caution.

  1. Proteomic analysis of oil body membrane proteins accompanying the onset of desiccation phase during sunflower seed development.

    Science.gov (United States)

    Thakur, Anita; Bhatla, Satish C

    2015-01-01

    A noteworthy metabolic signature accompanying oil body (OB) biogenesis during oilseed development is associated with the modulation of the oil body membranes proteins. Present work focuses on 2-dimensional polyacrylamide gel electrophoresis (2-D PAGE)-based analysis of the temporal changes in the OB membrane proteins analyzed by LC-MS/MS accompanying the onset of desiccation (20-30 d after anthesis; DAA) in the developing seeds of sunflower (Helianthus annuus L.). Protein spots unique to 20-30 DAA stages were picked up from 2-D gels for identification and the identified proteins were categorized into 7 functional classes. These include proteins involved in energy metabolism, reactive oxygen scavenging, proteolysis and protein turnover, signaling, oleosin and oil body biogenesis-associated proteins, desiccation and cytoskeleton. At 30 DAA stage, exclusive expressions of enzymes belonging to energy metabolism, desiccation and cytoskeleton were evident which indicated an increase in the metabolic and enzymatic activity in the cells at this stage of seed development (seed filling). Increased expression of cruciferina-like protein and dehydrin at 30 DAA stage marks the onset of desiccation. The data has been analyzed and discussed to highlight desiccation stage-associated metabolic events during oilseed development.

  2. Psychoneuroendocrine immunology: perception of stress can alter body temperature and natural killer cell activity.

    Science.gov (United States)

    Hiramoto, R N; Solvason, H B; Hsueh, C M; Rogers, C F; Demissie, S; Hiramoto, N S; Gauthier, D K; Lorden, J F; Ghanta, V K

    1999-01-01

    Psychoimmunology has been credited with using the mind as a way to alter immunity. The problem with this concept is that many of the current psychoimmunology techniques in use are aimed at alleviating stress effects on the immune system rather than at direct augmentation of immunity by the brain. Studies in animals provide a model that permits us to approach the difficulties associated with gaining an understanding of the CNS-immune system connection. A particular advantage of using animals over humans is that psychological and social contributions play a less prominent role for animals than for human subjects, since the animals are all inbred and reared under identical controlled conditions. If the insightful information provided by animal studies is correct, then psychotherapy for the treatment of diseases might be made more effective if some aspect of this knowledge is included in the design of the treatment. We emphasize conditioning as a regimen and an acceptable way to train the brain to remember an output pathway to raise immunity. We propose that a specific drug or perception (mild stress, represented by rotation, total body heating or handling) could substitute and kindle the same output pathway without the need for conditioning. If this view is correct, then instead of using conditioning, it may be possible to use an antigen to activate desired immune cells, and substitute a drug or an external environmental sensory stimulus (perception) to energize the output pathway to these cells. Alternatively, monitoring alterations of body temperature in response to a drug or perception might allow us to follow how effectively the brain is performing in altering immunity. Studies with animals suggest that there are alternative ways to use the mind to raise natural or acquired immunity in man.

  3. Immune activity, body condition and human-associated environmental impacts in a wild marine mammal.

    Directory of Open Access Journals (Sweden)

    Patrick M Brock

    Full Text Available Within individuals, immunity may compete with other life history traits for resources, such as energy and protein, and the damage caused by immunopathology can sometimes outweigh the protective benefits that immune responses confer. However, our understanding of the costs of immunity in the wild and how they relate to the myriad energetic demands on free-ranging organisms is limited. The endangered Galapagos sea lion (Zalophus wollebaeki is threatened simultaneously by disease from domestic animals and rapid changes in food availability driven by unpredictable environmental variation. We made use of this unique ecology to investigate the relationship between changes in immune activity and changes in body condition. We found that during the first three months of life, changes in antibody concentration were negatively correlated with changes in mass per unit length, skinfold thickness and serum albumin concentration, but only in a sea lion colony exposed to anthropogenic environmental impacts. It has previously been shown that changes in antibody concentration during early Galapagos sea lion development were higher in a colony exposed to anthropogenic environmental impacts than in a control colony. This study allows for the possibility that these relatively large changes in antibody concentration are associated with negative impacts on fitness through an effect on body condition. Our findings suggest that energy availability and the degree of plasticity in immune investment may influence disease risk in natural populations synergistically, through a trade-off between investment in immunity and resistance to starvation. The relative benefits of such investments may change quickly and unpredictably, which allows for the possibility that individuals fine-tune their investment strategies in response to changes in environmental conditions. In addition, our results suggest that anthropogenic environmental impacts may impose subtle energetic costs on

  4. Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies

    Science.gov (United States)

    West, Janne; Dahlqvist Leinhard, Olof; Romu, Thobias; Collins, Rory; Garratt, Steve; Bell, Jimmy D.; Borga, Magnus; Thomas, Louise

    2016-01-01

    Introduction Quantitative and accurate measurements of fat and muscle in the body are important for prevention and diagnosis of diseases related to obesity and muscle degeneration. Manually segmenting muscle and fat compartments in MR body-images is laborious and time-consuming, hindering implementation in large cohorts. In the present study, the feasibility and success-rate of a Dixon-based MR scan followed by an intensity-normalised, non-rigid, multi-atlas based segmentation was investigated in a cohort of 3,000 subjects. Materials and Methods 3,000 participants in the in-depth phenotyping arm of the UK Biobank imaging study underwent a comprehensive MR examination. All subjects were scanned using a 1.5 T MR-scanner with the dual-echo Dixon Vibe protocol, covering neck to knees. Subjects were scanned with six slabs in supine position, without localizer. Automated body composition analysis was performed using the AMRA Profiler™ system, to segment and quantify visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (ASAT) and thigh muscles. Technical quality assurance was performed and a standard set of acceptance/rejection criteria was established. Descriptive statistics were calculated for all volume measurements and quality assurance metrics. Results Of the 3,000 subjects, 2,995 (99.83%) were analysable for body fat, 2,828 (94.27%) were analysable when body fat and one thigh was included, and 2,775 (92.50%) were fully analysable for body fat and both thigh muscles. Reasons for not being able to analyse datasets were mainly due to missing slabs in the acquisition, or patient positioned so that large parts of the volume was outside of the field-of-view. Discussion and Conclusions In conclusion, this study showed that the rapid UK Biobank MR-protocol was well tolerated by most subjects and sufficiently robust to achieve very high success-rate for body composition analysis. This research has been conducted using the UK Biobank Resource. PMID:27662190

  5. Physical Activity and Health Perception in Aging: Do Body Mass and Satisfaction Matter? A Three-Path Mediated Link

    Science.gov (United States)

    Capranica, Laura; Stager, Joel; Forte, Roberta; Falbo, Simone; Di Baldassarre, Angela; Segura-Garcia, Cristina; Pesce, Caterina

    2016-01-01

    Although ageing people could benefit from healthy diet and physical activity to maintain health and quality of life, further understandings of the diet- and physical activity-related mechanisms that may cause changes in health and quality of life perception are necessary. The purpose of the study was to investigate the effect of eating attitudes, body mass and image satisfaction, and exercise dependence in the relationship between physical activity and health and quality of life perception in older individuals. Hundred and seventy-nine late middle-aged, (55–64 yrs), young-old (65–74 yrs), and old (75–84 yrs) senior athletes (n = 56), physically active (n = 58) or sedentary adults (n = 65) were submitted to anthropometric evaluations (body mass, height) and self-reported questionnaires: Body Image Dimensional Assessment, Exercise Dependence Scale, Eating Attitude Test, and Short Form Health Survey (Physical Component Summary [PCS] and Mental Component Summary [MCS] of and health and quality of life perception). Senior athletes, physically active, and sedentary participants subgroups differed (Pathletes showed, compared to their sedentary counterparts, further differences (Pmental health. The novelty of the three-path mediated link between physical activity level and mental health perception suggests that the beneficial effect of a physically active lifestyle on weight control can positively impinge on the cognitive-emotional dimension of mental health by ensuring the maintenance, also at older age, of a satisfactory body image. PMID:27611689

  6. Resistance training priming activity improves upper body power output in rugby players: Implications for game day performance.

    Science.gov (United States)

    Mason, Billy R J; Argus, Christos K; Norcott, Ben; Ball, Nick

    2016-07-05

    'Priming' or pre-activation strategies performed in the hours leading into competition have been suggested to improve game day performance. Therefore, this study assessed the effectiveness of a resistance training priming activity on eliciting changes in lower- and upper-body power output, along with perceptual measures. To assess these changes, 13 state level rugby players (aged 18.5 ± 0.5 years) completed a test retest protocol using a counterbalanced crossover design. Perceptual (readiness to perform questionnaire) and performance measures (20 kg counter-movement jump (CMJ), 20 kg bench throw) were completed prior to either a control (rest) or priming activity (four sets of three banded back squats and banded bench press). Following a one hour and 45 minute recovery period, perceptual and performance measures were repeated. Readiness to perform showed no meaningful differences pre and post intervention. Bench throw peak power (8.5 ± 5.8%, 90% confidence limit; ppriming activity when compared to the control trial. CMJ peak power (3.4 ± 4.9%; p>0.05) had a small decrease following the priming activity when compared with the control trial. Therefore, completing a priming activity one hour and 45 minutes prior to competition is recommended to improve upper body power output. However, further research into lower body priming protocols should be conducted before implementing a lower body priming activity prior to competition.

  7. Effects of obesity on occupant responses in frontal crashes: a simulation analysis using human body models.

    Science.gov (United States)

    Shi, Xiangnan; Cao, Libo; Reed, Matthew P; Rupp, Jonathan D; Hu, Jingwen

    2015-01-01

    The objective of this study is to investigate the effects of obesity on occupant responses in frontal crashes using whole-body human finite element (FE) models representing occupants with different obesity levels. In this study, the geometry of THUMS 4 midsize male model was varied using mesh morphing techniques with target geometries defined by statistical models of external body contour and exterior ribcage geometry. Models with different body mass indices (BMIs) were calibrated against cadaver test data under high-speed abdomen loading and frontal crash conditions. A parametric analysis was performed to investigate the effects of BMI on occupant injuries in frontal crashes based on the Taguchi method while controlling for several vehicle design parameters. Simulations of obese occupants predicted significantly higher risks of injuries to the thorax and lower extremities in frontal crashes compared with non-obese occupants, which is consistent with previous field data analyses. These higher injury risks are mainly due to the increased body mass and relatively poor belt fit caused by soft tissues for obese occupants. This study demonstrated the feasibility of using a parametric human FE model to investigate the obesity effects on occupant responses in frontal crashes.

  8. Antler and Body Size in Black-Tailed Deer: An Analysis of Cohort Effects

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    Johanna C. Thalmann

    2015-01-01

    Full Text Available For long-lived species, environmental factors experienced early in life can have lasting effects persisting into adulthood. Large herbivores can be susceptible to cohort-wide declines in fitness as a result of decreases in forage availability, because of extrinsic factors, including extreme climate or high population densities. To examine effects of cohort-specific extrinsic factors on size of adults, we performed a retrospective analysis on harvest data of 450 male black-tailed deer (Odocoileus hemionus columbianus over 19 years in central California, USA. We determined that population density of females had a more dominant effect than did precipitation on body size of males. Harvest of female deer resulted in increases in the overall size of males, even though a 6-year drought occurred during that treatment period. Body size was most influenced by female population density early in life, while antler size was highly affected by both weather early in life and the year directly before harvest. This study provides insights that improve our understanding of the role of cohort effects in body and antler size by cervids; and, in particular, that reduction in female population density can have a profound effect on the body and antler size of male deer.

  9. Dynamic Stability Analysis of Blunt Body Entry Vehicles Using Time-Lagged Aftbody Pitching Moments

    Science.gov (United States)

    Kazemba, Cole D.; Braun, Robert D.; Schoenenberger, Mark; Clark, Ian G.

    2013-01-01

    This analysis defines an analytic model for the pitching motion of blunt bodies during atmospheric entry. The proposed model is independent of the pitch damping sum coefficient present in the standard formulation of the equations of motion describing pitch oscillations of a decelerating blunt body, instead using the principle of a time-lagged aftbody moment as the forcing function for oscillation divergence. Four parameters, all with intuitive physical relevance, are introduced to fully define the aftbody moment and the associated time delay. It is shown that the dynamic oscillation responses typical to blunt bodies can be produced using hysteresis of the aftbody moment in place of the pitch damping coefficient. The approach used in this investigation is shown to be useful in understanding the governing physical mechanisms for blunt body dynamic stability and in guiding vehicle and mission design requirements. A validation case study using simulated ballistic range test data is conducted. From this, parameter identification is carried out through the use of a least squares optimizing routine. Results show good agreement with the limited existing literature for the parameters identified, suggesting that the model proposed could be validated by an experimental ballistic range test series. The trajectories produced by the identified parameters were found to match closely those from the MER ballistic range tests for a wide array of initial conditions and can be identified with a reasonable number of ballistic range shots and computational effort.

  10. An Efficient Full-Wave Electromagnetic Analysis for Capacitive Body-Coupled Communication

    Directory of Open Access Journals (Sweden)

    Muhammad Irfan Kazim

    2015-01-01

    Full Text Available Measured propagation loss for capacitive body-coupled communication (BCC channel (1 MHz to 60 MHz is limitedly available in the literature for distances longer than 50 cm. This is either because of experimental complexity to isolate the earth-ground or design complexity in realizing a reliable communication link to assess the performance limitations of capacitive BCC channel. Therefore, an alternate efficient full-wave electromagnetic (EM simulation approach is presented to realistically analyze capacitive BCC, that is, the interaction of capacitive coupler, the human body, and the environment all together. The presented simulation approach is first evaluated for numerical/human body variation uncertainties and then validated with measurement results from literature, followed by the analysis of capacitive BCC channel for twenty different scenarios. The simulation results show that the vertical coupler configuration is less susceptible to physiological variations of underlying tissues compared to the horizontal coupler configuration. The propagation loss is less for arm positions when they are not touching the torso region irrespective of the communication distance. The propagation loss has also been explained for complex scenarios formed by the ground-plane and the material structures (metals or dielectrics with the human body. The estimated propagation loss has been used to investigate the link-budget requirement for designing capacitive BCC system in CMOS sub-micron technologies.

  11. Static and dynamic stability analysis using 3D-DDA with incision body scheme

    Institute of Scientific and Technical Information of China (English)

    Wang Jianquan; Lin Gao; Liu Jun

    2006-01-01

    Discontinuous deformation analysis (DDA) provides a powerful numerical tool for the analysis of discontinuous media. This method has been widely applied to the 2D analysis of discontinuous deformation. However, it is hindered from analyzing 3D rock engineering problems mainly due to the lack of reliable 3D contact detection algorithms for polyhedra.Contact detection is a key in 3-D DDA analysis. The limitations and advantages of existing contact detection schemes are discussed in this paper, and a new approach, called the incision body (IB), is proposed, taking into account the advantages of the existing methods. A computer code 3DIB, which uses the IB scheme as a 3D contact detection algorithm, was programmed with Visual C++. Static and dynamic stability analysis for three realistic engineering problems has been carried out. Furthermore, the focus is on studying the stability of a gravity dam on jointed rock foundation and dynamic stability of a fractured gravity dam subject to earthquake shaking. The simulation results show that the program 3DIB and incision body scheme are capable of detecting 3D block contacts correctly and hence simulating the open-close and slide process of jointed block masses. In addition, the code 3DIB could provide an effective tool for evaluating the safety of 3D dam structures, which is quite important for engineering problems.

  12. Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: a meta-analysis of randomised controlled trials.

    Science.gov (United States)

    Booth, Alison O; Huggins, Catherine E; Wattanapenpaiboon, Naiyana; Nowson, Caryl A

    2015-10-14

    This meta-analysis of randomised controlled trials assessed the effect of Ca on body weight and body composition through supplementation or increasing dairy food intake. Forty-one studies met the inclusion criteria (including fifty-one trial arms; thirty-one with dairy foods (n 2091), twenty with Ca supplements (n 2711). Ca intake was approximately 900 mg/d higher in the supplement groups compared with control. In the dairy group, Ca intake was approximately 1300 mg/d. Ca supplementation did not significantly affect body weight (mean change ( - 0·17, 95% CI - 0·70, 0·37) kg) or body fat (mean change ( - 0·19, 95% CI - 0·51, 0·13) kg) compared to control. Similarly, increased dairy food intake did not affect body weight ( - 0·06, 95% CI - 0·54, 0·43) kg or body fat change ( - 0·36, 95% CI - 0·80, 0·09) kg compared to control. Sub-analyses revealed that dairy supplementation resulted in no change in body weight (nineteen studies, n 1010) ( - 0·32, 95% CI - 0·93, 0·30 kg, P= 0·31), but a greater reduction in body fat (thirteen studies, n 564) ( - 0·96, 95% CI - 1·46, - 0·46 kg, P supplements or increasing dairy intake to approximately 3 servings daily (approximately 1300 mg of Ca/d) is not an effective weight reduction strategy in adults. There is, however, an indication that approximately 3 servings of dairy may facilitate fat loss on weight reduction diets in the short term.

  13. Dynamic analysis on generalized linear elastic body subjected to large scale rigid rotations

    Institute of Scientific and Technical Information of China (English)

    刘占芳; 颜世军; 符志

    2013-01-01

    The dynamic analysis of a generalized linear elastic body undergoing large rigid rotations is investigated. The generalized linear elastic body is described in kine-matics through translational and rotational deformations, and a modified constitutive relation for the rotational deformation is proposed between the couple stress and the curvature tensor. Thus, the balance equations of momentum and moment are used for the motion equations of the body. The floating frame of reference formulation is applied to the elastic body that conducts rotations about a fixed axis. The motion-deformation coupled model is developed in which three types of inertia forces along with their incre-ments are elucidated. The finite element governing equations for the dynamic analysis of the elastic body under large rotations are subsequently formulated with the aid of the constrained variational principle. A penalty parameter is introduced, and the rotational angles at element nodes are treated as independent variables to meet the requirement of C1 continuity. The elastic body is discretized through the isoparametric element with 8 nodes and 48 degrees-of-freedom. As an example with an application of the motion-deformation coupled model, the dynamic analysis on a rotating cantilever with two spatial layouts relative to the rotational axis is numerically implemented. Dynamic frequencies of the rotating cantilever are presented at prescribed constant spin velocities. The maximal rigid rotational velocity is extended for ensuring the applicability of the linear model. A complete set of dynamical response of the rotating cantilever in the case of spin-up maneuver is examined, it is shown that, under the ultimate rigid rotational velocities less than the maximal rigid rotational velocity, the stress strength may exceed the material strength tolerance even though the displacement and rotational angle responses are both convergent. The influence of the cantilever layouts on their responses and

  14. Does body mass index (BMI) influence the Ankylosing Spondylitis Disease Activity Score in axial spondyloarthritis?

    Science.gov (United States)

    Rubio Vargas, Roxana; van den Berg, Rosaline; van Lunteren, Miranda; Ez-Zaitouni, Zineb; Bakker, Pauline A C; Dagfinrud, Hanne; Ramonda, Roberta; Landewé, Robert; Molenaar, Esmeralda; van Gaalen, Floris A; van der Heijde, Désirée

    2016-01-01

    Objective Obesity is associated with elevated C reactive protein (CRP) levels. The Ankylosing Spondylitis Disease Activity Score (ASDAS) combines patient-reported outcomes (PROs) and CRP. We evaluated the effect of body mass index (BMI) on CRP and on ASDAS, and studied if ASDAS can be used in obese axial spondyloarthritis (axSpA) patients to assess disease activity. Methods Baseline data of patients with chronic back pain of short duration included in the SPondyloArthritis Caught Early (SPACE) cohort were used. Collected data included BMI and ASDAS. Patients were classified according to the ASAS axSpA classification criteria and BMI (overweight ≥25 and obese ≥30). Correlation and linear regression analyses were performed to assess the relation between BMI and ASDAS. Linear regression models were performed to assess if age or gender were effect modifiers in the relation between BMI and CRP, and between BMI and ASDAS. Results In total, 428 patients were analysed (n=168 axSpA; n=260 no-axSpA). The mean age was 31.1 years, 36.9% were male, 26.4% were overweight and 13.3% obese, median CRP was 3 mg/L and the mean ASDAS was 2.6. Gender was the only factor modifying the relationship between BMI and CRP as BMI had an influence on CRP only in females (β=0.35; p<0.001). Correlations between BMI and CRP or PROs were generally weak, and only significant for CRP in female patients. BMI was not related to ASDAS in axSpA patients. Conclusions ASDAS is not affected by BMI in axSpA patients. Therefore, based on our data it is not necessary to take BMI in consideration when assessing disease activity using ASDAS in axSpA patients. PMID:27403336

  15. Energetic proton irradiation history of the HED parent body regolith and implications for ancient solar activity

    Science.gov (United States)

    Rao, M. N.; Garrison, D. H.; Palma, R. L.; Bogard, D. D.

    1997-07-01

    Previous studies have shown that the Kapoeta howardite, as well as several other meteorites, contain excess concentrations of cosmogenic neon in the darkened, solar-irradiated phase compared to the light, non-irradiated phase. The two explanations offered for the nuclear production of these Ne excesses in the parent body regolith are either from galactic particle (GCR) irradiation or from a greatly enhanced flux of energetic solar protons (SCR), as compared to the recent solar flux. Combining new isotopic data we obtained on acid-etched, separated feldspar from Kapoeta light and dark phases with literature data, we show that the cosmogenic 21Ne /22Ne ratio of light phase feldspar (0.80) is consistent with only GCR irradiation in space for ~3 Myr. However, the 21Ne/22Ne ratio (0.68) derived for irradiation of dark phase feldspar in the Kapoeta regolith indicates that cosmogenic Ne was produced in roughly equal proportions from galactic and solar protons. Considering a simple model of an immature Kapoeta parent body regolith, the duration of this early galactic exposure was only ~3-6 Myr, which would be an upper limit to the solar exposure time of individual grains. Concentrations of cosmogenic 21Ne in pyroxene separates and of cosmogenic 126Xe in both feldspar and pyroxene are consistent with this interpretation. The near-surface irradiation time of individual grains in the Kapoeta regolith probably varied considerably due to regolith mixing to an average GCR irradiation depth of ~10 cm. Because of the very different depth scales for production of solar ~Fe tracks, SCR Ne, and GCR Ne, the actual regolith exposure times for average grains probably differed correspondingly. However, both the SCR 21Ne and solar track ages appear to be longer because of enhanced production by early solar activity. The SCR/GCR production ratio of 21Ne inferred from the Kapoeta data is larger by a at least a factor of 10 and possibly as much as a factor of ~50 compared to recent solar

  16. Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells.

    Science.gov (United States)

    Into, Takeshi; Kanno, Yosuke; Dohkan, Jun-ichi; Nakashima, Misako; Inomata, Megumi; Shibata, Ken-ichiro; Lowenstein, Charles J; Matsushita, Kenji

    2007-03-16

    The endothelial cell-specific granule Weibel-Palade body releases vasoactive substances capable of modulating vascular inflammation. Although innate recognition of pathogens by Toll-like receptors (TLRs) is thought to play a crucial role in promotion of inflammatory responses, the molecular basis for early-phase responses of endothelial cells to bacterial pathogens has not fully been understood. We here report that human aortic endothelial cells respond to bacterial lipoteichoic acid (LTA) and synthetic bacterial lipopeptides, but not lipopolysaccharide or peptidoglycan, to induce Weibel-Palade body exocytosis, accompanied by release or externalization of the storage components von Willebrand factor and P-selectin. LTA could activate rapid Weibel-Palade body exocytosis through a TLR2- and MyD88-dependent mechanism without de novo protein synthesis. This process was at least mediated through MyD88-dependent phosphorylation and activation of phospholipase Cgamma. Moreover, LTA activated interleukin-1 receptor-associated kinase-1-dependent delayed exocytosis with de novo protein synthesis and phospholipase Cgamma-dependent activation of the NF-kappaB pathway. Increased TLR2 expression by transfection or interferon-gamma treatment increased TLR2-mediated Weibel-Palade body exocytosis, whereas reduced TLR2 expression under laminar flow decreased the response. Thus, we propose a novel role for TLR2 in induction of a primary proinflammatory event in aortic endothelial cells through Weibel-Palade body exocytosis, which may be an important step for linking innate recognition of bacterial pathogens to vascular inflammation.

  17. Causality Analysis of Inertial Body Sensors for Multiple Sclerosis Diagnostic Enhancement.

    Science.gov (United States)

    Gong, Jiaqi; Qi, Yanjun; Goldman, Myla D; Lach, John

    2016-09-01

    Inertial body sensors have emerged in recent years as an effective tool for evaluating mobility impairment resulting from various diseases, disorders, and injuries. For example, body sensors have been used in 6-min walk (6 MW) tests for multiple sclerosis (MS) patients to identify gait features useful in the study, diagnosis, and tracking of the disease. However, most studies to date have focused on features localized to the lower or upper extremities and do not provide a holistic assessment of mobility. This paper presents a causality analysis method focused on the coordination between extremities to identify subtle whole-body mobility impairment that may aid disease diagnosis. This method was developed for and utilized in an MS pilot study with 41 subjects (28 persons with MS (PwMS) and 13 healthy controls) performing 6 MW tests. Compared with existing methods, the causality analysis provided better discrimination between healthy controls and PwMS and a deeper understanding of MS disease impact on mobility.

  18. Activity of Ligninolytic Enzymes during Growth and Fruiting Body Development of White Rot Fungi Omphalina sp. and Pleurotus ostreatus

    Directory of Open Access Journals (Sweden)

    HAPPY WIDIASTUTI

    2008-12-01

    Full Text Available The activity of ligninolytic enzymes of white rot fungi (WRF Omphalina sp. and Pleurotus ostreatus was observed during somatic and fruiting body development in solid substrate fermentation using empty fruit bunches of oil palm (EFB. The enzyme activity was dominated by laccase both of Omphalina sp. and P. ostreatus. The laccase activity on somatic phase (mycelium growth was higher compared to that of fruiting body formation phase. The laccase activity of Omphalina sp. was slightly higher compared to that of P. ostreatus. The peak activity of manganese peroxidase (MnP for Omphalina sp. was observed two weeks after inoculation, while P. ostreatus had two peaks i.e. two and four weeks after inoculation period. The MnP activity of P. ostreatus was higher compared to that of Omphalina sp. Omphalina sp. growth in EFB did not secrete lignin peroxidase (LiP in contrast to P. ostreatus. The peak of LiP activity of P. ostreatus was reached two and four weeks after inoculation. The MnP and LiP activities declined during the development of fruiting bodies while laccase increased both in Omphalina sp. and P. ostreatus. It seems that the activities of ligninolytic enzyme profile were regulated in line with developmental phase of growth both in Omphalina sp. and P. ostreatus.

  19. Internal air flow analysis of a bladeless micro aerial vehicle hemisphere body using computational fluid dynamic

    Energy Technology Data Exchange (ETDEWEB)

    Othman, M. N. K., E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Zuradzman, M. Razlan, E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Hazry, D., E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Khairunizam, Wan, E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Shahriman, A. B., E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Yaacob, S., E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my; Ahmed, S. Faiz, E-mail: najibkhir86@gmail.com, E-mail: zuradzman@unimap.edu.my, E-mail: hazry@unimap.edu.my, E-mail: khairunizam@unimap.edu.my, E-mail: shahriman@unimap.edu.my, E-mail: s.yaacob@unimap.edu.my, E-mail: syedfaiz@unimap.edu.my, E-mail: abadal@unimap.edu.my [Centre of Excellence for Unmanned Aerial Systems, Universiti Malaysia Perlis, 01000 Kangar, Perlis (Malaysia); and others

    2014-12-04

    This paper explain the analysis of internal air flow velocity of a bladeless vertical takeoff and landing (VTOL) Micro Aerial Vehicle (MAV) hemisphere body. In mechanical design, before produce a prototype model, several analyses should be done to ensure the product's effectiveness and efficiency. There are two types of analysis method can be done in mechanical design; mathematical modeling and computational fluid dynamic. In this analysis, I used computational fluid dynamic (CFD) by using SolidWorks Flow Simulation software. The idea came through to overcome the problem of ordinary quadrotor UAV which has larger size due to using four rotors and the propellers are exposed to environment. The bladeless MAV body is designed to protect all electronic parts, which means it can be used in rainy condition. It also has been made to increase the thrust produced by the ducted propeller compare to exposed propeller. From the analysis result, the air flow velocity at the ducted area increased to twice the inlet air. This means that the duct contribute to the increasing of air velocity.

  20. Body composition of chronic renal patients: anthropometry and bioimpedance vector analysis

    Directory of Open Access Journals (Sweden)

    Viviane Soares

    2013-12-01

    Full Text Available OBJECTIVE: to compare the body composition of patients undergoing hemodialysis with that of healthy individuals using different methods. METHOD: cross-sectional study assessing male individuals using anthropometric markers, electrical bioimpedance and vector analysis. RESULTS: the healthy individuals presented larger triceps skinfold and arm circumference (p<0.001. The bioimpedance variables also presented significant higher values in this group. Significant difference was found in the confidence interval of the vector analysis performed for both the patients and healthy individuals (p<0.0001. The tolerance intervals showed that 55.20% of the patients were dehydrated, 10.30% presented visible edema, and 34.50% were within normal levels of hydration. Bioimpedance and vector analysis revealed that 52% of the patients presented decreased cell mass while 14.00% presented increased cell mass. CONCLUSIONS: the differences in the body composition of patients and healthy individuals were revealed through bioimpedance and vector analysis but not through their measures of arm circumference and arm muscle area.

  1. Internal air flow analysis of a bladeless micro aerial vehicle hemisphere body using computational fluid dynamic

    Science.gov (United States)

    Othman, M. N. K.; Zuradzman, M. Razlan; Hazry, D.; Khairunizam, Wan; Shahriman, A. B.; Yaacob, S.; Ahmed, S. Faiz; Hussain, Abadalsalam T.

    2014-12-01

    This paper explain the analysis of internal air flow velocity of a bladeless vertical takeoff and landing (VTOL) Micro Aerial Vehicle (MAV) hemisphere body. In mechanical design, before produce a prototype model, several analyses should be done to ensure the product's effectiveness and efficiency. There are two types of analysis method can be done in mechanical design; mathematical modeling and computational fluid dynamic. In this analysis, I used computational fluid dynamic (CFD) by using SolidWorks Flow Simulation software. The idea came through to overcome the problem of ordinary quadrotor UAV which has larger size due to using four rotors and the propellers are exposed to environment. The bladeless MAV body is designed to protect all electronic parts, which means it can be used in rainy condition. It also has been made to increase the thrust produced by the ducted propeller compare to exposed propeller. From the analysis result, the air flow velocity at the ducted area increased to twice the inlet air. This means that the duct contribute to the increasing of air velocity.

  2. Acoustic analysis of lightweight auto-body based on finite element method and boundary element method

    Institute of Scientific and Technical Information of China (English)

    LIANG Xinhua; ZHU Ping; LIN Zhongqin; ZHANG Yan

    2007-01-01

    A lightweight automotive prototype using alter- native materials and gauge thickness is studied by a numeri- cal method. The noise, vibration, and harshness (NVH) performance is the main target of this study. In the range of 1-150 Hz, the frequency response function (FRF) of the body structure is calculated by a finite element method (FEM) to get the dynamic behavior of the auto-body structure. The pressure response of the interior acoustic domain is solved by a boundary element method (BEM). To find the most contrib- uting panel to the inner sound pressure, the panel acoustic contribution analysis (PACA) is performed. Finally, the most contributing panel is located and the resulting structural optimization is found to be more efficient.

  3. Artificial Neural Network based Body Posture Classification from EMG signal analysis

    Directory of Open Access Journals (Sweden)

    Rajesh Kumar Tripathy

    2013-04-01

    Full Text Available  This paper deals with the body posture Classification from EMG signal analysis using artificial neural network (ANN. The various statistical features extracted from each EMG signal corresponding to different muscles associated with the different body postures are framed using LABVIEW software. Further-more, these features are taken as the input towards the ANN classifier and thus the corresponding output for the respective classifier predicts the postures like Bowing, Handshaking, and Hugging. The performance of the classifier is determined by the classification rate (CR. The outcome of result indicates that the CR of Multilayer Feed Forward Neural Network (MFNN type of ANN is rounded up to a percentage of 71.02%.

  4. Interrelationships between morphometric variables and rounded fish body yields evaluated by path analysis

    Directory of Open Access Journals (Sweden)

    Rafael Vilhena Reis Neto

    2012-07-01

    Full Text Available The objective of this study was to verify which morphometric measures and ratios are more directly associated with the weight and body yields of rounded fish. A total of 225 specimens of rounded fish (59 pacus, 61 tambaquis, 52 tambacus and 53 paquis with average weight of 972.43 g (±115.52 g were sampled, stunned, slaughtered, weighed, measured, and processed for morphometric and processing yield analysis. The morphometric measures taken were: standard length (CP; head length (CC; head height (AC; body height (A1; and body width (L1. For completeness, the following morphometric ratios were calculated: CC/CP, AC/CP, A1/CP, L1/CP, CC/A1, AC/A1, L1/A1, CC/AC and L1/CC. The yields of carcass, filet, rib and filet with rib were estimated after processing. Initially, a "stepwise" procedure was performed in order to eliminate multicollinearity problems among the morphometric variables, and the phenotypic correlations were then calculated for the dependent variables (weight and body yields and independent variables (morphometric measurements and ratios. These correlations were later deployed in direct and indirect effects through path analysis, and the direct and indirect contributions of each variable were measured in percentage terms. The CC and A1 measures were important for determining the weight of rounded fish. The CC/A1 ratio was the variable most directly associated with carcass yield. For filet, filet with rib and rib yields, the L1/CC ratio was found to be more appropriate and can be used directly.

  5. Controlled localization of functionally active proteins to inclusion bodies using leucine zippers.

    Directory of Open Access Journals (Sweden)

    Su-Lim Choi

    Full Text Available Inclusion bodies (IBs are typically non-functional particles of aggregated proteins. However, some proteins in fusion with amyloid-like peptides, viral coat proteins, and cellulose binding domains (CBDs generate IB particles retaining the original functions in cells. Here, we attempted to generate CBD IBs displaying functional leucine zipper proteins (LZs as bait for localizing cytosolic proteins in E. coli. When a red fluorescent protein was tested as a target protein, microscopic observations showed that the IBs red-fluoresced strongly. When different LZ pairs with KDs of 8-1,000 µM were tested as the bait and prey, the localization of the red fluorescence appeared to change following the affinities between the LZs, as observed by fluorescence imaging and flow cytometry. This result proposed that LZ-tagged CBD IBs can be applied as an in vivo matrix to entrap cytosolic proteins in E. coli while maintaining their original activities. In addition, easy detection of localization to IBs provides a unique platform for the engineering and analyses of protein-protein interactions in E. coli.

  6. A Review of the Role of Anticholinergic Activity in Lewy Body Disease and Delirium.

    Science.gov (United States)

    Kitajima, Yuka; Hori, Koji; Konishi, Kimiko; Tani, Masayuki; Tomioka, Hiroi; Akashi, Norihisa; Hosoi, Misa; Inamoto, Atsuko; Hasegawa, Sayaka; Kikuchi, Nodoka; Takahashi, Akari; Hachisu, Mitsugu

    2015-01-01

    We have previously proposed a hypothesis in which we argue that anticholinergic activity (AA) appears endogenously in Alzheimer's disease (AD). Acetylcholine (ACh) controls both cognitive function and inflammation. Consequently, when the downregulation of ACh reaches critical levels, the inflammatory system is upregulated and proinflammatory cytokines with AA appear. However, factors other than downregulation of ACh can produce AA; even if ACh downregulation does not reach critical levels, AA can still appear if one of these other AA-producing factors is added. These factors can include neurocognitive disorders other than AD, such as delirium and Lewy body disease (LBD). In delirium, ACh downregulation fails to reach critical levels, but AA appears due to the use of medicines, physical illnesses or mental stress (termed 'AA inserts'). In LBD, we speculate that AA appears endogenously, even in the absence of severe cognitive dysfunction, for 2 reasons. One reason is that patterns of ACh deterioration are different in LBD from those in AD, with synergistic actions between amyloid and α-synuclein thought to cause additional or severe symptoms that accelerate the disease course. The second reason is that AA occurs through disinhibition by reduced cortisol levels that result from severe autonomic parasympathetic dysfunction in LBD.

  7. Body dimensions, exercise capacity and physical activity level of adolescent Nandi boys in western Kenya

    DEFF Research Database (Denmark)

    Larsen, Henrik Bøgh; Christensen, Dirk Lund; Nolan, T

    2004-01-01

    maximal oxygen uptake (VO(2 max)) of 50 (range: 45-60) mL kg(-1) min(-1), whereas the village boys reached a value of 55 (37-63) mL kg(-1) min(-1) ( pVO(2 max). The running economy, determined as the oxygen cost at a given running speed, was 221 mL kg(-1) km(-1) (597 mL kg(-0.75) km(-1...... in the field: 44.2 (0-128) vs 1.3 (0-11) min, pVO(2 max) was found when pooling the data from the town and the village boys (R = 0.55, p... that the body dimensions of adolescent Nandi town and village boys corresponds well with findings in Kenyan elite runners. They are very slender with relatively long legs. In addition, the VO(2 max) of the village boys was higher than that of the town boys, which is probably due to a higher physical activity...

  8. a Modal Analysis of Whole-Body Vertical Vibration, Using a Finite Element Model of the Human Body

    Science.gov (United States)

    Kitazaki, S.; Griffin, M. J.

    1997-02-01

    A two-dimensional model of human biomechanical responses to whole-body vibration has been developed, by using the finite element method. Beam, spring and mass elements were used to model the spine, viscera, head, pelvis and buttocks tissue in the mid-sagittal plane. The model was developed by comparison of the vibration mode shapes with those previously measured in the laboratory. At frequencies below 10 Hz, the model produced seven modes which coincided well with the measurements. The principal resonance of the driving point response at about 5 Hz consisted of an entire body mode, in which the head, spinal column and the pelvis move almost rigidly, with axial and shear deformation of tissue beneath the pelvis occurring in phase with a vertical visceral mode. The second principal resonance at about 8 Hz corresponded to a rotational mode of the pelvis, with a possible contribution from a second visceral mode. A shift of the principal resonance of the driving point response, when changing posture, was achieved only by changing the axial stiffness of the buttocks tissue. It is suggested that an increase in contact area between the buttocks and the thighs and the seat surface, when changing posture from erect to slouched, may decrease the axial stiffness beneath the pelvis, with a non-linear force-deflection relationship of tissue resulting in decreases in the natural frequencies. A change in posture from erect to slouched also increased shear deformation of tissue beneath the pelvis in the entire body mode, and the natural frequency was decreased as a result of the much lower shear stiffness of tissue compared to the axial stiffness.

  9. "Mortui vivos docent" or who gives his body to science? The analysis of the personal questionnaires of Polish donors in the Conscious Body Donation Program.

    Directory of Open Access Journals (Sweden)

    Grzegorz Bajor

    Full Text Available The Conscious Body Donation Program conducted since 2003 by the Department of Human Anatomy, Medical University of Silesia in Katowice was the first innovative project aimed at obtaining informed donors' bodies for the purpose of teaching anatomy in Poland. The aim of this prospective study was to determine the declared donors' characteristics and to establish the possible motivation for body donation. A total of 244 application files were reviewed and the following information was analyzed: donor's age, age at which the decision to donate the body was made, donor's place of residence and declared nationality, family background, education and profession, family structure and religion. Our results showed that mainly elderly people decided to donate their bodies (68.5 ± 11.84 years, living mostly in large and medium-sized cities. Men--donors often lived in small towns. Most of the donors were of blue-collar parentage, completed secondary education and at the time of taking decision to donate where married and retired. Widows were more likely to make the decision to donate than widowers. Most of our donors were Catholic. Our analysis of the profile of Polish donors may be useful to understand better for which groups of people death is not to be perceived as the end, and may become a value, which can be beneficial to living people.

  10. "Mortui vivos docent" or who gives his body to science? The analysis of the personal questionnaires of Polish donors in the Conscious Body Donation Program.

    Science.gov (United States)

    Bajor, Grzegorz; Likus, Wirginia; Kuszewski, Piotr; Kostro, Karol; Łoś, Andrzej; Kłakus, Piotr

    2015-01-01

    The Conscious Body Donation Program conducted since 2003 by the Department of Human Anatomy, Medical University of Silesia in Katowice was the first innovative project aimed at obtaining informed donors' bodies for the purpose of teaching anatomy in Poland. The aim of this prospective study was to determine the declared donors' characteristics and to establish the possible motivation for body donation. A total of 244 application files were reviewed and the following information was analyzed: donor's age, age at which the decision to donate the body was made, donor's place of residence and declared nationality, family background, education and profession, family structure and religion. Our results showed that mainly elderly people decided to donate their bodies (68.5 ± 11.84 years), living mostly in large and medium-sized cities. Men--donors often lived in small towns. Most of the donors were of blue-collar parentage, completed secondary education and at the time of taking decision to donate where married and retired. Widows were more likely to make the decision to donate than widowers. Most of our donors were Catholic. Our analysis of the profile of Polish donors may be useful to understand better for which groups of people death is not to be perceived as the end, and may become a value, which can be beneficial to living people.

  11. The association between body-built and injury occurrence in pre-professional ballet dancers – Separated analysis for the injured body-locations

    Directory of Open Access Journals (Sweden)

    Petra Zaletel

    2017-02-01

    Full Text Available Objectives: This study has aimed at identifying prevalence of injury-occurrence in 24 pre-professional-ballet-dancers (females, 16–18 years of age, and identifying the associations between the body-built and prevalence of injuries. Material and Methods: The sample of variables included: body mass, body height, and 3 somatotype characteristics (mesomorph, ectomorph and endomorph and data on injuries over the preceding year. Results: Dancers were mostly ectomorphic-mesomorph (endomorphy: 2.6±0.54, mesomorphy: 3.99±0.77, ectomorphy: 3.23±0.54. The most commonly injured locations were the foot (17% of all injuries and ankle (17%. Majority of the injuries occurred while practising but 37% of hip-injuries occurred while performing. Ankle-injuries resulted in longest absence from ballet. Endomorphy was related to ankle-injury (odds ratio (OR = 1.9, 95% confidence interval (CI: 1.4–2.3, ectomorphy to foot injury (OR = 1.7, 95% CI: 1.1–2.9, and body-mass to injury to the toes (OR = 1.7, 95% CI: 1.4–3.1. Conclusions: The results of this study allow for recognizing those dancers who are particularly vulnerable to injuries of certain body location. A more profound analysis of the possible mechanisms that lead to hip-injury during performance is needed. Int J Occup Med Environ Health 2017;30(1:151–159

  12. Transcriptional network analysis in frontal cortex in Lewy body diseases with focus on dementia with Lewy bodies.

    Science.gov (United States)

    Santpere, Gabriel; Garcia-Esparcia, Paula; Andres-Benito, Pol; Lorente-Galdos, Belen; Navarro, Arcadi; Ferrer, Isidro

    2017-03-21

    The present study investigates global transcriptional changes in frontal cortex area 8 in incidental Lewy Body disease (iLBD), Parkinson disease (PD) and Dementia with Lewy bodies (DLB). We identified different co-expressed gene sets associated with disease stages, and gene ontology categories enriched in gene modules and differentially expressed genes including modules or gene clusters correlated to iLBD comprising upregulated dynein genes and taste receptors, and down-regulated innate inflammation. Focusing on DLB, we found modules with genes significantly enriched in functions related to RNA and DNA production, mitochondria and energy metabolism, purine metabolism, chaperone and protein folding system, and synapses and neurotransmission (particularly the GABAergic system). The expression of more than fifty selected genes was assessed with RT-qPCR. Our findings provide, for the first time, evidence of molecular cortical alterations in iLBD and involvement of several key metabolic pathways and gene hubs in DLB which may underlie cognitive impairment and dementia. This article is protected by copyright. All rights reserved.

  13. Strength Training Improves Body Image and Physical Activity Behaviors among Midlife and Older Rural Women

    Science.gov (United States)

    Seguin, Rebecca A.; Eldridge, Galen; Lynch, Wesley; Paul, Lynn C.

    2013-01-01

    The effect of strength training on body image is understudied. The Strong Women Program, a 10-week, twice weekly strength-training program, was provided by Extension agents to 341 older rural women (62 ± 12 years); changes in body image and other psychosocial variables were evaluated. Paired-sample t-test analyses were conducted to assess mean…

  14. Multi-flexible-body analysis for application to wind turbine control design

    Science.gov (United States)

    Lee, Donghoon

    The objective of the present research is to build a theoretical and computational framework for the aeroelastic analysis of flexible rotating systems, more specifically with special application to a wind turbine control design. The methodology is based on the integration of Kane's approach for the analysis of the multi-rigid-body subsystem and a mixed finite element method for the analysis of the flexible-body subsystem. The combined analysis is then strongly coupled with an aerodynamic model based on Blade Element Momentum theory for inflow model. The unified framework from the analysis of subsystems is represented as, in a symbolic manner, a set of nonlinear ordinary differential equations with time-variant, periodic coefficients, which describe the aeroelastic behavior of whole system. The framework can be directly applied to control design due to its symbolic characteristics. The solution procedures for the equations are presented for the study of nonlinear simulation, periodic steady-state solution, and Floquet stability of the linearized system about the steady-state solution. Finally the linear periodic system equation can be obtained with both system and control matrices as explicit functions of time, which can be directly applicable to control design. The structural model is validated by comparison of its results with those from software, some of which is commercial. The stability of the linearized system about periodic steady-state solution is different from that obtained about a constant steady-state solution, which have been conventional in the field of wind turbine dynamics. Parametric studies are performed on a wind turbine model with various pitch angles, precone angles, and rotor speeds. Combined with composite material, their effects on wind turbine aeroelastic stability are investigated. Finally it is suggested that the aeroelastic stability analysis and control design for the whole system is crucial for the design of wind turbines, and the

  15. Small and inconsistent effects of whole body vibration on athletic performance : a systematic review and meta-analysis

    NARCIS (Netherlands)

    Hortobagyi, Tibor; Lesinski, Melanie; Fernandez-del-Olmo, Miguel; Granacher, Urs

    2015-01-01

    We quantified the acute and chronic effects of whole body vibration on athletic performance or its proxy measures in competitive and/or elite athletes. Systematic literature review and meta-analysis. Whole body vibration combined with exercise had an overall 0.3 % acute effect on maximal voluntary l

  16. Skin Sensitive Difference of Human Body Sections under Clothing--Multiple Analysis of Skin Surface Temperature Changes

    Institute of Scientific and Technical Information of China (English)

    李俊; 吴海燕; 张渭源

    2003-01-01

    A new researching method on clothing comfort perception is developed.By it the skin surface temperature changes and subjective psychological perception of human body sections stimulated by the same cold stimulation are studied.With the multiple comparison analysis method the changing laws of skin temperature of main human body sections is obtained.

  17. Fusion-activated Ca(2+ entry: an "active zone" of elevated Ca(2+ during the postfusion stage of lamellar body exocytosis in rat type II pneumocytes.

    Directory of Open Access Journals (Sweden)

    Pika Miklavc

    Full Text Available Ca(2+ is essential for vesicle fusion with the plasma membrane in virtually all types of regulated exocytoses. However, in contrast to the well-known effects of a high cytoplasmic Ca(2+ concentration ([Ca(2+](c in the prefusion phase, the occurrence and significance of Ca(2+ signals in the postfusion phase have not been described before.We studied isolated rat alveolar type II cells using previously developed imaging techniques. These cells release pulmonary surfactant, a complex of lipids and proteins, from secretory vesicles (lamellar bodies in an exceptionally slow, Ca(2+- and actin-dependent process. Measurements of fusion pore formation by darkfield scattered light intensity decrease or FM 1-43 fluorescence intensity increase were combined with analysis of [Ca(2+](c by ratiometric Fura-2 or Fluo-4 fluorescence measurements. We found that the majority of single lamellar body fusion events were followed by a transient (t(1/2 of decay = 3.2 s rise of localized [Ca(2+](c originating at the site of lamellar body fusion. [Ca(2+](c increase followed with a delay of approximately 0.2-0.5 s (method-dependent and in the majority of cases this signal propagated throughout the cell (at approximately 10 microm/s. Removal of Ca(2+ from, or addition of Ni(2+ to the extracellular solution, strongly inhibited these [Ca(2+](c transients, whereas Ca(2+ store depletion with thapsigargin had no effect. Actin-GFP fluorescence around fused LBs increased several seconds after the rise of [Ca(2+](c. Both effects were reduced by the non-specific Ca(2+ channel blocker SKF96365.Fusion-activated Ca(2+entry (FACE is a new mechanism that leads to [Ca(2+](c transients at the site of vesicle fusion. Substantial evidence from this and previous studies indicates that fusion-activated Ca(2+ entry enhances localized surfactant release from type II cells, but it may also play a role for compensatory endocytosis and other cellular functions.

  18. Different body mass index grade on the risk of developing glioma: a meta-analysis

    Institute of Scientific and Technical Information of China (English)

    Zifeng Dai; Qilin Huang; Haipeng Liu

    2015-01-01

    Background: Previous studies reported conflicting results about the risk of developing glioma and different body mass index.So we decided to execute a meta-analysis to solve the dispute.Methods: Comprehensive literature retrieval was carried in PubMed, MEDLINE, and EMBASE up to September 15, 2014.Hand literature information retrieval was not carried.Six studies were fit for this meta-analysis.Pooled hazard ratio (HR) and 95 % confidence interval (CI) of different body mass index grade were performed by fixed/random-effects models, except for normal weight which was referent.Results: Data of 3726 cases were included.Compared with normal weight (20 kg.m-2 < body mass index (BMI) ≤ 24.9 kg.m-2), the underweight (BMI ≤ 20 kg.m-2) might have lower incidence on the risk of developing glioma (HR =1.08, 95 % CI ranged 0.74 to 1.58, P =0.678).While the overweight (25 kg.m-2 < BMI ≤ 29.9 kg.m-2)and obesity (BMI ≥ 30 kg.m-2) were performed as a risk factor of developing glioma.The pooled HR of overweight group was 1.12 (95 % CI ranged 1.02 to 1.22, P=0.013);the pooled HR of obesity was 1.14 (95 % CI ranged 1.02 to 1.27, P =0.017).Sensitivity analysis approved that our results were stable.There was no publication bias of these studies.Conclusions: Underweight could decrease the risk of developing glioma.Excess BMI was considered as a risk factor to develop glioma.

  19. Physical Activity Advertisements That Feature Daily Well-Being Improve Autonomy and Body Image in Overweight Women but Not Men

    Directory of Open Access Journals (Sweden)

    Michelle L. Segar

    2012-01-01

    Full Text Available The reasons for exercising that are featured in health communications brand exercise and socialize individuals about why they should be physically active. Discovering which reasons for exercising are associated with high-quality motivation and behavioral regulation is essential to promoting physical activity and weight control that can be sustained over time. This study investigates whether framing physical activity in advertisements featuring distinct types of goals differentially influences body image and behavioral regulations based on self-determination theory among overweight and obese individuals. Using a three-arm randomized trial, overweight and obese women and men (aged 40–60 yr, n=1690 read one of three ads framing physical activity as a way to achieve (1 better health, (2 weight loss, or (3 daily well-being. Framing effects were estimated in an ANOVA model with pairwise comparisons using the Bonferroni correction. This study showed that there are immediate framing effects on physical activity behavioral regulations and body image from reading a one-page advertisement about physical activity and that gender and BMI moderate these effects. Framing physical activity as a way to enhance daily well-being positively influenced participants’ perceptions about the experience of being physically active and enhanced body image among overweight women, but not men. The experiment had less impact among the obese study participants compared to those who were overweight. These findings support a growing body of research suggesting that, compared to weight loss, framing physical activity for daily well-being is a better gain-frame message for overweight women in midlife.

  20. Physical activity advertisements that feature daily well-being improve autonomy and body image in overweight women but not men.

    Science.gov (United States)

    Segar, Michelle L; Updegraff, John A; Zikmund-Fisher, Brian J; Richardson, Caroline R

    2012-01-01

    The reasons for exercising that are featured in health communications brand exercise and socialize individuals about why they should be physically active. Discovering which reasons for exercising are associated with high-quality motivation and behavioral regulation is essential to promoting physical activity and weight control that can be sustained over time. This study investigates whether framing physical activity in advertisements featuring distinct types of goals differentially influences body image and behavioral regulations based on self-determination theory among overweight and obese individuals. Using a three-arm randomized trial, overweight and obese women and men (aged 40-60 yr, n = 1690) read one of three ads framing physical activity as a way to achieve (1) better health, (2) weight loss, or (3) daily well-being. Framing effects were estimated in an ANOVA model with pairwise comparisons using the Bonferroni correction. This study showed that there are immediate framing effects on physical activity behavioral regulations and body image from reading a one-page advertisement about physical activity and that gender and BMI moderate these effects. Framing physical activity as a way to enhance daily well-being positively influenced participants' perceptions about the experience of being physically active and enhanced body image among overweight women, but not men. The experiment had less impact among the obese study participants compared to those who were overweight. These findings support a growing body of research suggesting that, compared to weight loss, framing physical activity for daily well-being is a better gain-frame message for overweight women in midlife.

  1. Effects of glucagon-like peptide-1 receptor agonists on body weight: a meta-analysis.

    Science.gov (United States)

    Monami, Matteo; Dicembrini, Ilaria; Marchionni, Niccolò; Rotella, Carlo M; Mannucci, Edoardo

    2012-01-01

    Glucagon-Like Peptide-1 receptor agonists (GLP-1RAs), approved as glucose-lowering drugs for the treatment of type 2 diabetes, have also been shown to reduce body weight. An extensive Medline, Cochrane database, and Embase search for "exenatide," "liraglutide," "albiglutide," "semaglutide," and "lixisenatide" was performed, collecting all randomized clinical trials on humans up to December 15, 2011, with a duration of at least 24 weeks, comparing GLP-1 receptor agonists with either placebo or active drugs. Twenty two (7,859 patients) and 7 (2,416 patients) trials with available results on body weight at 6 and 12 months, respectively, were included. When compared with placebo, GLP-1RAs determine a reduction of BMI at 6 months of -1.0 [-1.3; -0.6] kg/m(2). Considering the average BMI at baseline (32.4 kg/m(2)) these data means a weight reduction of about 3% at 6 months. This result could seem modest from a clinical standpoint; however, it could be affected by many factors contributing to an underestimation of the effect of GLP-1RA on body weight, such as non adequate doses, inclusion criteria, efficacy of GLP-1RA on reducing glycosuria, and association to non-pharmacological interventions not specifically aimed to weight reduction.

  2. Effects of Glucagon-Like Peptide-1 Receptor Agonists on Body Weight: A Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Matteo Monami

    2012-01-01

    Full Text Available Glucagon-Like Peptide-1 receptor agonists (GLP-1RAs, approved as glucose-lowering drugs for the treatment of type 2 diabetes, have also been shown to reduce body weight. An extensive Medline, Cochrane database, and Embase search for “exenatide,” “liraglutide,” “albiglutide,” “semaglutide,” and “lixisenatide” was performed, collecting all randomized clinical trials on humans up to December 15, 2011, with a duration of at least 24 weeks, comparing GLP-1 receptor agonists with either placebo or active drugs. Twenty two (7,859 patients and 7 (2,416 patients trials with available results on body weight at 6 and 12 months, respectively, were included. When compared with placebo, GLP-1RAs determine a reduction of BMI at 6 months of −1.0 [−1.3; −0.6] kg/m2. Considering the average BMI at baseline (32.4 kg/m2 these data means a weight reduction of about 3% at 6 months. This result could seem modest from a clinical standpoint; however, it could be affected by many factors contributing to an underestimation of the effect of GLP-1RA on body weight, such as non adequate doses, inclusion criteria, efficacy of GLP-1RA on reducing glycosuria, and association to non-pharmacological interventions not specifically aimed to weight reduction.

  3. Associations among self-perceived work and life stress, trouble sleeping, physical activity, and body weight among Canadian adults.

    Science.gov (United States)

    Sampasa-Kanyinga, Hugues; Chaput, Jean-Philippe

    2017-03-01

    We investigated the associations among self-perceived work and life stress, trouble sleeping, physical activity and body weight among Canadian adults, and tested whether trouble sleeping and physical activity moderated the relationship between work/life stress and body weight, and whether work/life stress and physical activity moderated the relationship between trouble sleeping and body weight. Data on 13,926 Canadian adults aged 20years and older were derived from the nationally representative 2012 Canadian Community Health Survey. After adjusting for age, sex, education level, household income, marital status and job insecurity, self-perceived work and life stress and trouble sleeping were associated with a higher BMI. The associations of work and life stress with higher BMI were independent of trouble sleeping and physical activity in addition to other covariates, while that of trouble sleeping and higher BMI was independent of work and life stress. Results further indicated that trouble sleeping among inactive participants was related to a higher BMI; however, this relationship was almost null for adults who self-reported being physically active for about 8h/week. These findings suggest that work and life stress are both associated with excess weight in adults, regardless of physical activity level, while the link of trouble sleeping with BMI varies by physical activity level. Future research is necessary to determine whether reducing work and life stress and improving sleep habits would benefit the prevention of weight gain and obesity.

  4. Noise Analysis of an Lightweight Auto-body Using FEM/BEM

    Institute of Scientific and Technical Information of China (English)

    LI Zai-wei; ZHU Ping; LIANG Xin-hua

    2007-01-01

    Since numeric simulation can save much costs, it is widely used in automobile design. Besides, noise, vibration and harshness(NVH) performance is one major target for enginer to design a competitive product. In this paper, NVH performance of a lightweight auto-body prototype using alternative materials and gauge thickness were studied by finite element method (FEM) and boundary element method (BEM). In order to find the most contributing panel to the peak value of response, the panel acoustic contribution analysis (PACA) was performed and the most effective modification area was located. Finally, the sound pressure was reduced by putting damping material on these parts.

  5. Nuclear Pairing from Two-body Microscopic Forces: Analysis of the Cooper Pair Wavefunctions

    CERN Document Server

    Finelli, P; Holt, J W

    2014-01-01

    In a recent paper we studied the behavior of the pairing gaps $\\Delta_F$ as a function of the Fermi momentum $k_F$ for neutron and nuclear matter in all relevant angular momentum channels where superfluidity is believed to naturally emerge. The calculations employed realistic chiral nucleon-nucleon potentials with the inclusion of three-body forces and self-energy effects. In this contribution, after a detailed description of the numerical method we employed in the solution of the BCS equations, we will show a preliminary analysis of the Cooper pair wavefunctions.

  6. Scaling analysis of paces of fetal breathing, gross-body and extremity movements

    OpenAIRE

    Govindan, R. B.; Wilson, J D; Murphy, P; Russel, W.A.; Lowery, C L

    2007-01-01

    Using detrended fluctuation analysis (DFA), we studied the scaling properties of the time instances (occurrence) of the fetal breathing, gross-body, and extremity movements scored on a second by second basis from the recorded ultrasound measurements of 49 fetuses. The DFA exponent α of all the three movements of the fetuses varied between 0.63 and 1.1. We found an increase in α obtained for the movement due to breathing as a function of the gestational age while this trend was not observed fo...

  7. Body electrical loss analysis (BELA) in the assessment of visceral fat: a demonstration

    OpenAIRE

    Blomqvist Kim H; Lundbom Jesper; Lundbom Nina; Sepponen Raimo E

    2011-01-01

    Abstract Background Body electrical loss analysis (BELA) is a new non-invasive way to assess visceral fat depot size through the use of electromagnetism. BELA has worked well in phantom measurements, but the technology is not yet fully validated. Methods Ten volunteers (5 men and 5 women, age: 22-60 y, BMI: 21-30 kg/m2, waist circumference: 73-108 cm) were measured with the BELA instrument and with cross-sectional magnetic resonance imaging (MRI) at the navel level, navel +5 cm and navel -5 c...

  8. Association of Body Mass Index with Depression, Anxiety and Suicide-An Instrumental Variable Analysis of the HUNT Study.

    Directory of Open Access Journals (Sweden)

    Johan Håkon Bjørngaard

    Full Text Available While high body mass index is associated with an increased risk of depression and anxiety, cumulative evidence indicates that it is a protective factor for suicide. The associations from conventional observational studies of body mass index with mental health outcomes are likely to be influenced by reverse causality or confounding by ill-health. In the present study, we investigated the associations between offspring body mass index and parental anxiety, depression and suicide in order to avoid problems with reverse causality and confounding by ill-health.We used data from 32,457 mother-offspring and 27,753 father-offspring pairs from the Norwegian HUNT-study. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale and suicide death from national registers. Associations between offspring and own body mass index and symptoms of anxiety and depression and suicide mortality were estimated using logistic and Cox regression. Causal effect estimates were estimated with a two sample instrument variable approach using offspring body mass index as an instrument for parental body mass index.Both own and offspring body mass index were positively associated with depression, while the results did not indicate any substantial association between body mass index and anxiety. Although precision was low, suicide mortality was inversely associated with own body mass index and the results from the analysis using offspring body mass index supported these results. Adjusted odds ratios per standard deviation body mass index from the instrumental variable analysis were 1.22 (95% CI: 1.05, 1.43 for depression, 1.10 (95% CI: 0.95, 1.27 for anxiety, and the instrumental variable estimated hazard ratios for suicide was 0.69 (95% CI: 0.30, 1.63.The present study's results indicate that suicide mortality is inversely associated with body mass index. We also found support for a positive association between body mass index and depression, but not

  9. Numerical acoustic analysis of a turbulent flow around a bluff body

    Science.gov (United States)

    Cianferra, Marta; Ianniello, Sandro; Armenio, Vincenzo

    2016-11-01

    A body invested by a fluid flow gives rise to vortical and turbulent three-dimensional fields, whose structure depends on the shape of the body itself and the Reynolds number. Then, pressure fluctuations occur in the field and propagate far away as noise. The acoustic analogy based on the Ffowcs Williams-Hawkings (FWH) equation represents a rigorous way to deal with the problem, enabling the evaluation of noise through a post-processing of fluid dynamic data. Moreover, the presence of separate source terms theoretically allows to identify the dominant generating noise mechanisms taking place in the flow, which, of course, repre- sents a key information in view of any possible reduction or alteration of the acoustic field. This paper deals with a numerical, FWH-based acoustic analysis of a turbulent flow around a bluff body and, in particular, a 3D square cylinder in a uniform velocity field. The fluid dynamic solution is obtained through Large eddy simulations carried out using a standard Smagorinsky model at different Reynolds numbers. The acoustic solution is pursued by different integral solution forms of the FWH equation, in the attempt of recognizing the main noise sources and pointing out the potentiality and possible weak-points of the alternative numerical approaches.

  10. Prompt gamma-ray activation analysis (PGAA)

    Energy Technology Data Exchange (ETDEWEB)

    Kern, J. [Fribourg Univ. (Switzerland). Inst. de Physique

    1996-11-01

    The paper deals with a brief description of the principles of prompt gamma-ray activation analysis (PGAA), with the detection of gamma-rays, the PGAA project at SINQ and with the expected performances. 8 figs., 3 tabs., 10 refs.

  11. Transforming Teacher Education, An Activity Theory Analysis

    Science.gov (United States)

    McNicholl, Jane; Blake, Allan

    2013-01-01

    This paper explores the work of teacher education in England and Scotland. It seeks to locate this work within conflicting sociocultural views of professional practice and academic work. Drawing on an activity theory framework that integrates the analysis of these seemingly contradictory discourses with a study of teacher educators' practical…

  12. Physical activity, diet and gene-environment interactions in relation to body mass index and waist circumference

    DEFF Research Database (Denmark)

    Karnehed, Nina; Tynelius, Per; Heitmann, Berit L

    2006-01-01

    OBJECTIVE: The aim of the present study was to examine the relationships between genetic susceptibility to obesity, physical activity (PA), dietary fibre, sugar and fat intakes and 4-year changes in body mass index (BMI) and attained waist circumference (WC) in a cohort of 287 monozygotic and 189...

  13. Whole body 3-methylhistidine production and proteinase activities in porcine muscle after protein-free feeding and realimentation.

    NARCIS (Netherlands)

    Hemel-Grooten, van den H.N.A.; Rathmacher, J.A.; Garssen, G.J.; Schreurs, V.V.A.M.; Verstegen, M.W.A.

    1998-01-01

    Whole body 3-methylhistidine (3MH) production rates and proteinase activities in porcine skeletal muscles were studied during a protein-free feeding period and subsequent realimentation. Out of 54 castrated male pigs (35 kg on day 0), six pigs were slaughtered on day 0, and 48 were randomly divided

  14. A Second Chance: Meanings of Body Weight, Diet, and Physical Activity to Women Who Have Experienced Cancer

    Science.gov (United States)

    Maley, Mary; Warren, Barbour S.; Devine, Carol M.

    2013-01-01

    Objective: To understand the meanings of diet, physical activity, and body weight in the context of women's cancer experiences. Design: Grounded theory using 15 qualitative interviews and 3 focus groups. Setting: Grassroots community cancer organizations in the northeastern United States. Participants: Thirty-six white women cancer survivors; 86%…

  15. Mind magic: a pilot study of preventive mind-body-based stress reduction in behaviorally inhibited and activated children

    NARCIS (Netherlands)

    Jellesma, F.C.; Cornelis, J.

    2012-01-01

    Purpose of study: The aim of this pilot study was to examine a mind-body-based preventive intervention program and to determine relationships between children's behavioral inhibition system (BIS) and behavioral activation system, stress, and stress reduction after the program. Design of study: Child

  16. IMPACT OF GENETIC STRAIN ON BODY FAT LOSS, FOOD CONSUMPTION, METABOLISM, VENTILATION, AND MOTOR ACTIVITY IN FREE RUNNING FEMALE RATS

    Science.gov (United States)

    Physiologic data associated with different strains of common laboratory rat strains.This dataset is associated with the following publication:Gordon , C., P. Phillips , and A. Johnstone. Impact of Genetic Strain on Body Fat Loss, Food Consumption, Metabolism, Ventilation, and Motor Activity in Free Running Female Rats. PHYSIOLOGY AND BEHAVIOR. Elsevier Science Ltd, New York, NY, USA, 153: 56-63, (2016).

  17. Inter-relationships among physical activity, body fat, and motor performance in 6- to 8-year-old Danish children

    DEFF Research Database (Denmark)

    Morrison, Kyle M; Bugge, Anna; El-Naaman, Bianca

    2012-01-01

    This study examined the interrelationships among physical activity (PA), percent body fat (%BF), and motor performance (MP) in 498 6- to 8-year-old Danish children. PA was assessed by accelerometer, %BF was calculated from skinfolds, and the Koordinations Test für Kinder along with a throwing...

  18. Private farmers’ annual exposure to whole body vibration from the aspect of the type of agricultural and transport activities performed

    OpenAIRE

    Leszek Solecki

    2012-01-01

    The objective of the study was hygienic evaluation of farmers’ exposure to whole body vibration from the aspect of the type of agricultural and transport activities performed during the whole year. Twenty farms were selected for the study using arable land of over 10 ha, engaged in mixed production (plant-animal). The scope of the study covered measurements of mechanical vibration (acceleration) on seats of agricultural vehicles while performing various field and transport activities, t...

  19. INHIBITING GERANYLGERANYLATION INCREASES NEURITE BRANCHING AND DIFFERENTIALLY ACTIVATES COFILIN IN CELL BODIES AND GROWTH CONES

    Science.gov (United States)

    Samuel, Filsy; Reddy, Jairus; Kaimal, Radhika; Segovia, Vianey; Mo, Huanbiao; Hynds, DiAnna L.

    2014-01-01

    Inhibitors of the mevalonate pathway, including the highly prescribed statins, reduce the production of cholesterol and isoprenoids such as geranylgeranyl pyrophosphates. The Rho family of small guanine triphosphatases (GTPases) requires isoprenylation, specifically geranylgeranylation, for activation. Because Rho GTPases are primary regulators of actin filament rearrangements required for process extension, neurite arborization and synaptic plasticity, statins may affect cognition or recovery from nervous system injury. Here, we assessed how manipulating geranylgeranylation affects neurite initiation, elongation and branching in neuroblastoma growth cones. Treatment with the statin, lovastatin (20 μM) decreased measures of neurite initiation by 17.0% to 19.0% when a source of cholesterol was present and increased neurite branching by 4.03 to 9.54 fold (regardless of exogenous cholesterol). Neurite elongation was increased by treatment with lovastatin only in cholesterol-free culture conditions. Treatment with lovastatin decreased growth cone actin filament content by up to 24.3%. In all cases, co-treatment with the prenylation precursor, geranylgeraniol (10 μM), reversed the effect of lovastatin. In prior work, statin effects on outgrowth were linked to modulating the actin depolymerizing factor, cofilin. In our assays, treatment with lovastatin or geranylgeraniol decreased cofilin phosphorylation in whole cell lysates. However, lovastatin increased cofilin phosphorylation in cell bodies and decreased it in growth cones, indicating differential regulation in specific cell regions. Together, we interpret these data to suggest that protein geranylgeranylation likely regulates growth cone actin filament content and subsequent neurite outgrowth through mechanisms that also affect actin nucleation and polymerization. PMID:24515839

  20. Whole Body Irradiation Induces Cutaneous Dendritic Cells Depletion via NF-κB Activation

    Directory of Open Access Journals (Sweden)

    Yanyong Yang

    2013-07-01

    Full Text Available Background: Effect of ionizing radiation on cutaneous dendritic cells (cDC is critical to its influence on immune status of the skin, which plays an important role in the progression and recovery of radiation skin sickness. This study was to study the influence of whole body irradiation (WBI on the cDC. Methods: Density of epidermal and dermal DC was determined with a fluorescent microscopy and the DC numbers in lymph node were measured by flow cytometry. A FITC induced migration assay was also used to study the migration of DC. The expressions of cytokines and chemokines were evaluated by Realtime PCR, and the protein level of was measured by Western blot. Results: WBI caused depletion of cDC in epidermal as well as dermal and augmented FITC-induced migration of DC to the draining lymph node (LN. The number of DC migrated from ear explants to the CCL19-containing medium also increased after exposure to WBI. It was also found that WBI increased mRNA level of CCL19/CCL21 as well as CCR7 in LN and skin tissue. The expressions of TNFa, IL-1a, IL-1ß, and IL-6 in skin tissues were also greatly induced by WBI in a dose dependent manner. Finally, we found that WBI induced translocation of nuclear factor κB (NF-κB and that the radiation-induced migration of DC was blocked by NF-κB inhibitor or TLR4 knockout. Conclusion: WBI caused cDC depletion through induction of DC migration to the draining LN, which might result from the activation of NF-κB and the induction of inflammatory microenvironment within the skin.

  1. Analysis of Aggregation Delay for Multisource Sensor Data with On-Off Traffic Pattern in Wireless Body Area Networks

    Science.gov (United States)

    Kim, Un-Ha; Kong, Eutteum; Choi, Hyun-Ho; Lee, Jung-Ryun

    2016-01-01

    Data aggregation plays an important role to improve the transmission efficiency in wireless body area networks (WBANs); however, it inherently induces additional aggregation delay. Therefore, the effect of packet aggregation on WBAN applications, which are vulnerable to delay, must be analyzed rigorously. In this paper, we analyze the packet aggregation delay for multisource sensor data with an on-off traffic pattern in WBANs. Considering two operational parameters of the aggregation threshold and aggregation timer, we calculate the probability that a packet aggregation occurs during a unit time and then derive the average aggregation delay in closed-form. The analysis results show that the aggregation delay increases as the aggregation timer or aggregation threshold increases, but is bounded below a certain level according to the number of active sensors and their on-off traffic attribute. This implies that the data aggregation technique can maximize the transmission efficiency while satisfying a given delay requirement in the WBAN system. PMID:27706029

  2. Crashworthiness Analysis of a Minibus Body in White Through Reverse Engineering

    Institute of Scientific and Technical Information of China (English)

    王青春; 范子杰; 桂良进; 陈宗渝; 宋宏伟

    2004-01-01

    To investigate the crashworthiness of a minibus body in white (BIW) and create a digital model for further analysis and improvement, the crash behavior of the BIW was quantitatively analyzed using reverse engineering.Each part of the BIW was identified and digitalized to conduct a finite element model.A frontal crash was simulated numerically using the explicit finite element analysis software LS-DYNA.BIW crash tests were conducted to validate the finite element model.The computational results agree well with the test data, not only for the collapse mode, but also in the force-time and acceleration-time correlation curves.The methods used to create the finite element model can be used to further improve or develop safer vehicles.

  3. Dynamic analysis of a floating body in the fluid by using the smoothed particle hydrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Jun, Chul Woong; Sohn, Jeong Hyun; Lee, Kyung Chang [Pukyong National University, Busan (Korea, Republic of)

    2015-07-15

    This paper describes a method for the prediction of behavior of a floating-type structure using an experiment and numerical analysis according to the various marine conditions. The sloshing simulation is considered to verify the behavior of fluid. The fluid is expressed by a set of particles, the motion of fluid is calculated by using SPH (Smoothed particle hydrodynamics). Numerical results are compared with experiments. A wave tank and linear shaker are used in order to express the sloshing environment. Monaghan boundary force is employed to calculate the interacting force between fluid and boundary. Four wave periods are used to consider the various marine conditions in the fluid-structure interacting simulation. The longitudinal motion of a floating body is compared to each other. As a result, the solution of numerical analysis shows the similar tendency compared to the experiment results.

  4. Cross-linguistic Analysis of Body Part Metaphor Conceptualization from a Cognitive Semiosis Perspective

    Directory of Open Access Journals (Sweden)

    Sara Atef-Vahid

    2013-09-01

    Full Text Available In accordance with Lakovian cognitive linguistics in metaphoric analysis, this paper aims to explore the human cognitive capacity of metaphoric conceptualization of body parts. A contrastive analysis on the cognitive features of metaphorical expressions utilizing various body parts pertaining to the ‘head’ domain, e.g., face and tongue in the English and Farsi languages is carriedout. After a cross-linguistic comparison of metaphors in both languages, five main linguistic categories emerge. Similarities and differences of metaphor construction, mappings and mechanisms in both languages used to convey common concepts are highlighted using these categories. While corroborating Lakoff’s approach whereby metaphors constitute an inherent part oflanguage itself, it is shown that there is a universal cognitive grid from which different languages externalize the world differently through semiosis. Therefore, the main aim is to show how language invariance and variation may be explained within a cognitive framework. These universals are due to cognitive constraints, whereas languages owe their variation to the optionsthey have out of the cognitively available pool. They are limited to their selections which are restrained by cultural and perhaps religious factors of semiotic mechanisms which are cognitively accessible to them.

  5. A novel method for the measurement of linear body segment parameters during clinical gait analysis.

    Science.gov (United States)

    Geil, Mark D

    2013-09-01

    Clinical gait analysis is a valuable tool for the understanding of motion disorders and treatment outcomes. Most standard models used in gait analysis rely on predefined sets of body segment parameters that must be measured on each individual. Traditionally, these parameters are measured using calipers and tape measures. The process can be time consuming and is prone to several sources of error. This investigation explored a novel method for rapid recording of linear body segment parameters using magnetic-field based digital calipers commonly used for a different purpose in prosthetics and orthotics. The digital method was found to be comparable to traditional in all linear measures and data capture was significantly faster with the digital method, with mean time savings for 10 measurements of 2.5 min. Digital calipers only record linear distances, and were less accurate when diameters were used to approximate limb circumferences. Experience in measuring BSPs is important, as an experienced measurer was significantly faster than a graduate student and showed less difference between methods. Comparing measurement of adults vs. children showed greater differences with adults, and some method-dependence. If the hardware is available, digital caliper measurement of linear BSPs is accurate and rapid.

  6. Analysis of coelom development in the sea urchin Holopneustes purpurescens yielding a deuterostome body plan.

    Science.gov (United States)

    Morris, Valerie B

    2016-01-01

    An analysis of early coelom development in the echinoid Holopneustes purpurescens yields a deuterostome body plan that explains the disparity between the pentameral plan of echinoderms and the bilateral plans of chordates and hemichordates, the three major phyla of the monophyletic deuterostomes. The analysis shows an early separation into a medial hydrocoele and lateral coelomic mesoderm with an enteric channel between them before the hydrocoele forms the pentameral plan of five primary podia. The deuterostome body plan thus has a single axial or medial coelom and a pair of lateral coeloms, all surrounding an enteric channel, the gut channel. Applied to the phyla, the medial coelom is the hydrocoele in echinoderms, the notochord in chordates and the proboscis coelom in hemichordates: the lateral coeloms are the coelomic mesoderm in echinoderms, the paraxial mesoderm in chordates and the lateral coeloms in hemichordates. The plan fits frog and chick development and the echinoderm fossil record, and predicts genes involved in coelomogenesis as the source of deuterostome macroevolution.

  7. Analysis of coelom development in the sea urchin Holopneustes purpurescens yielding a deuterostome body plan

    Directory of Open Access Journals (Sweden)

    Valerie B. Morris

    2016-03-01

    Full Text Available An analysis of early coelom development in the echinoid Holopneustes purpurescens yields a deuterostome body plan that explains the disparity between the pentameral plan of echinoderms and the bilateral plans of chordates and hemichordates, the three major phyla of the monophyletic deuterostomes. The analysis shows an early separation into a medial hydrocoele and lateral coelomic mesoderm with an enteric channel between them before the hydrocoele forms the pentameral plan of five primary podia. The deuterostome body plan thus has a single axial or medial coelom and a pair of lateral coeloms, all surrounding an enteric channel, the gut channel. Applied to the phyla, the medial coelom is the hydrocoele in echinoderms, the notochord in chordates and the proboscis coelom in hemichordates: the lateral coeloms are the coelomic mesoderm in echinoderms, the paraxial mesoderm in chordates and the lateral coeloms in hemichordates. The plan fits frog and chick development and the echinoderm fossil record, and predicts genes involved in coelomogenesis as the source of deuterostome macroevolution.

  8. Analysis of structure of lumbar spine dorsopathy morbidity in able-bodied age patients

    Directory of Open Access Journals (Sweden)

    Manin M.V.

    2015-06-01

    Full Text Available The analysis of structure of lumbar spine dorsopathy morbidity among able-bodied population of the Dnepropetrovsk area for substantiation of differentiated approach to the choice of exercise therapy methods was a research objective. The structure of dorsopathy morbidity in 371 patients in 2009-2013 period is analysed in the work. The paper presents analysis of the most frequent morphological changes in the structures of the spine, their localization and clinical course. Link of clinical manifestations of dorsopathy with structural changes of the backbone, the disease experience is revealed, efficiency of rehabilitation by means of physiotherapy exercises depending on qualitative and quantitative signs of disease is defined. Results of the research specify that more than 40% of patients were on repeated treatment, clinical manifestation in 62% of patients was observed at the most able-bodied age (from 30 to 50 years, according to the disease experience number of aggravations per a year increased, in 57,5% of cases administration of medical physical culture was limited due to development of an accompanying pathology, in 40% of cases against positive dynamics of painful syndrome insufficient changes in volume of movements of the spine segments throughout treatment were marked. It testifies to necessity of working out algorithm of differentiated approach to the choice of means medical physical culture in treatment of lumbar spine dorsopathy.

  9. Body painting to promote self-active learning of hand anatomy for preclinical medical students

    OpenAIRE

    Jariyapong, Pitchanee; Punsawad, Chuchard; Bunratsami, Suchirat; Kongthong, Paranyu

    2016-01-01

    Background: The purpose of this study was to use the body painting method to teach hand anatomy to a group of preclinical medical students.Methods: Students reviewed hand anatomy using the traditional method and body painting exercise. Feedback and retention of the anatomy-related information were examined by a questionnaire and multiple-choice questions, respectively, immediately and 1 month after the painting exercise.Results: Students agreed that the exercise was advantageous and helped fa...

  10. Mediating relationship between body mass index and the direct measures of the Theory of Planned Behaviour on physical activity intention.

    Science.gov (United States)

    Caperchione, Cristina M; Duncan, Mitch J; Mummery, Kerry; Steele, Rebekah; Schofield, Grant

    2008-03-01

    This research examines (a) the interrelationships between body mass index (BMI), the direct measures of the Theory of Planned Behaviour (TPB) and physical activity intention and (b) the potential mediation effects of the direct measures of the TPB in the relationship between BMI and physical activity intention in a sample of Australian adults. A total sample of 1,062 respondents participated in a computer-assisted telephone-interview (CATI) survey comprised of a standardised introduction; questions regarding TPB and physical activity; and standard demographic questions. BMI for each participant was calculated from self-reported height and weight. Separate regression analyses were performed to examine the mediating effects of each of the direct measures of the TPB on the predictive relationship between the BMI and physical activity intention, as proposed by Baron and Kenny (Journal of Personality and Social Psychology, 51(6), 1173 - 1182, 1986). Findings indicated that the direct measure of attitude and perceived behavioural control mediated the relationship between BMI and physical activity intention. However, the direct measure of subjective norm failed to act as a mediating mechanism. To date there has been no research that has examined the mechanism by which body mass may affect physical activity behaviour. Given the current focus for health promotion specialists on promoting physical activity as a strategy for reducing overweight and obesity, a theoretical understanding of weight-related barriers to physical activity may aid in the development of future interventions and community physical activity programs, particularly those targeting overweight and obese populations.

  11. Bone mineral density and body composition in a myelomeningocele children population: effects of walking ability and sport activity.

    Science.gov (United States)

    Ausili, E; Focarelli, B; Tabacco, F; Fortunelli, G; Caradonna, P; Massimi, L; Sigismondi, M; Salvaggio, E; Rendeli, C

    2008-01-01

    Myelomeningocele causes serious locomotor disability, osteoporosis and pathologic fractures. The aim of this study was to investigate the relationship between body composition, bone mineral density, walking ability and sport activity in myelomeningocele children. 60 patients aged between 5 and 14 yrs with myelomeningocele (22 ambulatory and 38 non-ambulatory), were studied. Fat mass and fat-free-mass were calculated by anthropometry. The bone mineral density at lumbar and femoral neck were evaluated. Bone mineral density at the lumbar and femoral neck was lower than in the normal population. In the non-ambulaty group, bone mineral density was approximately 1 SD lower than in the ambulatory one (p sport activity had a better bone mineral density and body fat compared with other patients with the same disability. Patients with myelomeningocele have decreased bone mineral density and are at higher risk of pathologic bone fractures. All subjects showed an excess of fat as percentage of body weight and are shorter than normal children. The measurement of bone mineral density may help to identify those patients at greatest risk of suffering of multiple fractures. Walk ability and sport activity, associated with the development of muscle mass, are important factors in promoting bone and body growth, to reduce the risk of obesity and of pathological fractures.

  12. DNA damage focus analysis in blood samples of minipigs reveals acute partial body irradiation.

    Directory of Open Access Journals (Sweden)

    Andreas Lamkowski

    Full Text Available Radiation accidents frequently involve acute high dose partial body irradiation leading to victims with radiation sickness and cutaneous radiation syndrome that implements radiation-induced cell death. Cells that are not lethally hit seek to repair ionizing radiation (IR induced damage, albeit at the expense of an increased risk of mutation and tumor formation due to misrepair of IR-induced DNA double strand breaks (DSBs. The response to DNA damage includes phosphorylation of histone H2AX in the vicinity of DSBs, creating foci in the nucleus whose enumeration can serve as a radiation biodosimeter. Here, we investigated γH2AX and DNA repair foci in peripheral blood lymphocytes of Göttingen minipigs that experienced acute partial body irradiation (PBI with 49 Gy (± 6% Co-60 γ-rays of the upper lumbar region. Blood samples taken 4, 24 and 168 hours post PBI were subjected to γ-H2AX, 53BP1 and MRE11 focus enumeration. Peripheral blood lymphocytes (PBL of 49 Gy partial body irradiated minipigs were found to display 1-8 DNA damage foci/cell. These PBL values significantly deceed the high foci numbers observed in keratinocyte nuclei of the directly γ-irradiated minipig skin regions, indicating a limited resident time of PBL in the exposed tissue volume. Nonetheless, PBL samples obtained 4 h post IR in average contained 2.2% of cells displaying a pan-γH2AX signal, suggesting that these received a higher IR dose. Moreover, dispersion analysis indicated partial body irradiation for all 13 minipigs at 4 h post IR. While dose reconstruction using γH2AX DNA repair foci in lymphocytes after in vivo PBI represents a challenge, the DNA damage focus assay may serve as a rapid, first line indicator of radiation exposure. The occurrence of PBLs with pan-γH2AX staining and of cells with relatively high foci numbers that skew a Poisson distribution may be taken as indicator of acute high dose partial body irradiation, particularly when samples are available

  13. Activity Analysis and Cost Analysis in Medical Schools.

    Science.gov (United States)

    Koehler, John E.; Slighton, Robert L.

    There is no unique answer to the question of what an ongoing program costs in medical schools. The estimates of program costs generated by classical methods of cost accounting are unsatisfactory because such accounting cannot deal with the joint production or joint cost problem. Activity analysis models aim at calculating the impact of alternative…

  14. Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men.

    Science.gov (United States)

    Sugita, Jun; Yoneshiro, Takeshi; Hatano, Takuya; Aita, Sayuri; Ikemoto, Takeshi; Uchiwa, Hideyo; Iwanaga, Toshihiko; Kameya, Toshimitsu; Kawai, Yuko; Saito, Masayuki

    2013-08-01

    Brown adipose tissue (BAT) is responsible for cold- and diet-induced thermogenesis, and thereby contributes to the control of whole-body energy expenditure (EE) and body fat content. BAT activity can be assessed by fluoro-2-deoxyglucose (FDG)-positron emission tomography (PET) in human subjects. Grains of paradise (GP, Aframomum melegueta), a species of the ginger family, contain pungent, aromatic ketones such as 6-paradol, 6-gingerol and 6-shogaol. An alcohol extract of GP seeds and 6-paradol are known to activate BAT thermogenesis in small rodents. The present study aimed to examine the effects of the GP extract on whole-body EE and to analyse its relation to BAT activity in men. A total of nineteen healthy male volunteers aged 20-32 years underwent FDG-PET after 2 h of exposure to cold at 19°C with light clothing. A total of twelve subjects showed marked FDG uptake into the adipose tissue of the supraclavicular and paraspinal regions (BAT positive). The remaining seven showed no detectable uptake (BAT negative). Within 4 weeks after the FDG-PET examination, whole-body EE was measured at 27°C before and after oral ingestion of GP extract (40 mg) in a single-blind, randomised, placebo-controlled, crossover design. The resting EE of the BAT-positive group did not differ from that of the BAT-negative group. After GP extract ingestion, the EE of the BAT-positive group increased within 2 h to a significantly greater (Pwhole-body EE through the activation of BAT in human subjects.

  15. Multiscale statistical analysis of coronal solar activity

    CERN Document Server

    Gamborino, Diana; Martinell, Julio J

    2016-01-01

    Multi-filter images from the solar corona are used to obtain temperature maps which are analyzed using techniques based on proper orthogonal decomposition (POD) in order to extract dynamical and structural information at various scales. Exploring active regions before and after a solar flare and comparing them with quiet regions we show that the multiscale behavior presents distinct statistical properties for each case that can be used to characterize the level of activity in a region. Information about the nature of heat transport is also be extracted from the analysis.

  16. Influence of age, menopause status, body mass index and physical activity on body composition and body fat distribution in midlife women%中年妇女年龄、月经状态、体重指数及体力活动对机体组成及脂肪分布的影响

    Institute of Scientific and Technical Information of China (English)

    魏代敏; 郁琦; 张颖; 陈凤领

    2012-01-01

    Objective: To investigate the influence of age, menopause status, body mass index (BMI) and physical activity on body composition and body fat distribution in Chinese midlife women. Methods: The healthy women who underwent anniversary health checkup in Peking Union Medical College Hospital were recruited cross-sectionally. The level of physical activity was determined via International Physical Activity Questionare-Short in Chinese Version. The body composition and fat distribution were measured by dual-energy X-ray absorptiometry. Results: A total of 162 women with average age 52 years (40-62 years) were collected. Multiple linear regression analysis was performed to test the relationship between age, menopause status, BMI and physical activity and parameters of body composition & body fat distribution. The total fat tissue percentage was positively associated with BMI (standardized partial regression coefficient; b = 0. 70), menopause status (b = 0. 19, grading variable 1, 2, 3) were assigned to represent for reproductive group, menopausal transition group and postmenopausal group, respectively, and negatively associated with physical activity energy expenditure (b=-0. 17) with model determination coefficient 0. 55. Total body fat-free mass was positively associated with BMI (b = 0. 61) , negatively associated with menopause status (b=-0. 14) with model determination coefficient 0. 39. The ratio of trunk fat tissue/total body fat tissue was positively related with BMI (b = 0. 32) and menopause status (b = 0. 30) with model determination coefficient 0. 20. After adjusted the effects of BMI, menopause status and physical activity, age was not significantly related with total fat tissue percentage, body fat-free mass, nor ratio of trunk fat tissue/total body fat tissue. Conclusions: Menopause impact body composition and body fat distribution independently. During the process of female reproductive aging, body fat tissue mass increases and becomes more susceptible to

  17. The Effect of Reduced Physical Activity and Retraining on Blood Lipids and Body Composition in Young and Older Adult Men

    DEFF Research Database (Denmark)

    Nørregaard, Jesper; Gram, Martin; Vigelsø, Andreas

    2015-01-01

    We studied the effect of physical inactivity and subsequent re-training on cardiovascular risk factors in seventeen young (Y; 23.4±0.5) and fifteen older adult (O; 68.1±1.1 yrs.) men who underwent 14 days of one leg immobilization followed by six weeks of training. Body weight remained unchanged....... Daily physical activity decreased by 31±9 (Y) and 37±9 (O) % (P... increased with reduced activity (Pphysical activity for two weeks increases blood lipids in both Y and O men. Six weeks of training improved...

  18. Mechanisms of Earth activity forsed by external celestial bodies:energy budjet and nature of cyclicity

    Science.gov (United States)

    Barkin, Yu. V.; Ferrandiz, J. M.

    2003-04-01

    In given report we discuss tidal and non-tidal mechanisms of forced tectonic (endogenous) activity of the Earth caused by gravitational attraction of the Moon, Sun and the planets. On the base of the classical solution of the problem of elasticity for model of the Earth with concentric mass distribution the evaluations of the tidal energy and power of Earth lunar-solar deformations, including their joint effect, were obtained. Important role of the joint energetic effect of rotational deformation of the Earth with lunar and solar tides was illustrated. Gravitational interaction of the Moon and Sun with non-spherical, non-homogeneous shells of the Earth generates big additional mechanical forces and moments of the interaction of the neighboring shells (rigid core, liquid core, mantle, lithosphere and separate plates). Acting of these forces and moments in the different time scales on the corresponding sells generates cyclic perturbations of the tensional state of the shells, their deformations, small relative translational displacements and small relative rotational oscillations of the shells. In geological period of time it leads to a fundamental tectonic reconstruction of the Earth. These additional forces and moments of the cyclic celestial-mechanical nature produce cyclic deformations of the all layers of the body and organize and control practically all natural processes. The additional force between mantle and core is cyclic and characterized by the wide basis of frequencies typical for orbital motions (of the Sun, Moon and planets), for rotational motion of the Earth, Moon and Sun and for many from observed natural processes. The problem about small relative translatory-rotary motion of the two shells separated by the thin viscous-elastic layer is studied. The differential equations of motion were obtained and have been studied in particular cases (plane motion of system; case of two axisymmetrical interacting shells and oth.) by approximate methods of small

  19. Dietary fibre consumption and insulin resistance - the role of body fat and physical activity.

    Science.gov (United States)

    Breneman, Charity B; Tucker, Larry

    2013-07-28

    The present study was conducted to determine the association between fibre intake and insulin resistance in 264 women using a cross-sectional design. Insulin resistance was indexed using homeostasis model assessment of insulin resistance (HOMA-IR) (US formula: fasting insulin (μU/ml) × fasting glucose (mg/dl)/405 international formula: fasting glucose (mmol/l) × fasting insulin (μU/l)/22.5). Fibre and energy consumption were assessed using 7 d weighed food records. Fibre was expressed as g/4184 kJ (1000 kcal). Body fat percentage (BF%) was measured using the BOD POD, and physical activity (PA) was ascertained using Actigraph accelerometers (Health One Technology) worn for seven consecutive days. Women with high total fibre intakes (F= 4·58, P= 0·0332) or high soluble fibre intakes (F= 7·97, P= 0·0051) had significantly less insulin resistance than their counterparts. Participants with high insoluble fibre intakes did not differ from their counterparts (F= 0·7, P= 0·6875). Adjusting for either PA or BF% weakened the relationships significantly. Controlling for BF% nullified the total fibre–HOMA-IR link (F= 1·96, P= 0·1631) and attenuated the association between soluble fibre and HOMA-IR by 32 % (F= 6·86, P= 0·0094). To create dichotomous variables, fibre intake and HOMA-IR were each divided into two categories using the median (low and high). In women who had high soluble fibre intake (upper 50 %), the OR of having an elevated HOMA-IR level was 0·58 (95 % CI 0·36, 0·94) times that of women with low soluble fibre intake (lower 50 %). After controlling for all of the potential confounding factors simultaneously, the OR was 0·52 (95 % CI 0·29, 0·93). High fibre intake, particularly soluble fibre, is significantly related to lower levels of insulin resistance in women. Part of this association is a function of differences in PA and BF%.

  20. The formation of multivesicular bodies in activated blastocysts is influenced by autophagy and FGF signaling in mice

    Science.gov (United States)

    Shin, Hyejin; Bang, Soyoung; Kim, Jiyeon; Jun, Jin Hyun; Song, Haengseok; Lim, Hyunjung Jade

    2017-01-01

    Dormant blastocysts during delayed implantation undergo autophagic activation, which is an adaptive response to prolonged survival in utero during less favorable environment. We observed that multivesicular bodies (MVBs) accumulate in the trophectoderm of dormant blastocysts upon activation for implantation. Since autophagosomes are shown to fuse with MVBs and efficient autophagic degradation requires functional MVBs, we examined if MVB formation in activated blastocysts are associated with protracted autophagic state during dormancy. We show here that autophagic activation during dormancy is one precondition for MVB formation in activated blastocysts. Furthermore, the blockade of FGF signaling with PD173074 partially interferes with MVB formation in these blastocysts, suggesting the involvement of FGFR signaling in this process. We believe that MVB formation in activated blastocysts after dormancy is a potential mechanism of clearing subcellular debris accumulated during prolonged autophagy. PMID:28155881

  1. GabaB receptors activation in the NTS blocks the glycemic responses induced by carotid body receptor stimulation.

    Science.gov (United States)

    Lemus, Mónica; Montero, Sergio; Cadenas, José Luis; Lara, José Jesús; Tejeda-Chávez, Héctor Rafael; Alvarez-Buylla, Ramón; de Alvarez-Buylla, Elena Roces

    2008-08-18

    The carotid body receptors participate in glucose regulation sensing glucose levels in blood entering the cephalic circulation. The carotid body receptors information, is initially processed within the nucleus tractus solitarius (NTS) and elicits changes in circulating glucose and brain glucose uptake. Previous work has shown that gamma-aminobutyric acid (GABA) in NTS modulates respiratory reflexes, but the role of GABA within NTS in glucose regulation remains unknown. Here we show that GABA(B) receptor agonist (baclofen) or antagonists (phaclofen and CGP55845A) locally injected into NTS modified arterial glucose levels and brain glucose retention. Control injections outside NTS did not elicit these responses. In contrast, GABA(A) agonist and antagonist (muscimol or bicuculline) produced no significant changes in blood glucose levels. When these GABAergic drugs were applied before carotid body receptors stimulation, again, only GABA(B) agonist or antagonist significantly affected glycemic responses; baclofen microinjection significantly reduced the hyperglycemic response and brain glucose retention observed after carotid body receptors stimulation, while phaclofen produced the opposite effect, increasing significantly hyperglycemia and brain glucose retention. These results indicate that activation of GABA(B), but not GABA(A), receptors in the NTS modulates the glycemic responses after anoxic stimulation of the carotid body receptors, and suggest the presence of a tonic inhibitory mechanism in the NTS to avoid hyperglycemia.

  2. Immunohistochemical and morphometric analysis of immunoglobulin light-chain immunoreactive amyloid in psammoma bodies of the human choroid plexus.

    Science.gov (United States)

    Jovanović, Ivan; Ugrenović, Sladjana; Vasović, Ljiljana; Stojanović, Ivan

    2014-03-01

    The aim of this research was to establish the presence of amyloid and to quantify immunohistochemical reactions of kappa and lambda light chains of psammoma bodies of the choroid plexus. Choroid plexus tissue obtained from 14 right lateral ventricles postmortem was processed histologically and stained with Congo red, thioflavin T, and monoclonal antibodies for kappa and lambda light chains. Morphological analysis was performed with a light microscope at lens magnifications of 4×, 10×, 20×, 25×, and 40×. The morphometric characteristics of psammoma bodies that were kappa and lambda positive and negative were analyzed with ImageJ. Histological analysis showed that the psammoma bodies, stromal blood vessel walls, and some epithelial cells reacted positively with Congo red and thioflavin T. Psammoma bodies were predominantly positive for lambda light chains. Lambda positivity was detected inside some stromal blood vessels, which pointed to a probable systemic origin for these light chains. Morphometric analysis showed that the mean optical densities of lambda- and kappa-positive psammoma bodies were significantly higher than those that gave a negative reaction. The percentage of lambda-positive psammoma bodies was significantly higher than the percentage of lambda-negative psammoma bodies in 80% of the cases, while the reaction with kappa light chains was negative in the majority of the cases. Linear regression analysis showed a significant increase in the percentage of lambda-positive psammoma bodies and their mean optical density with age. Finally, it can be concluded that the positive reaction of psammoma bodies in the choroid plexus with respect to amyloid and lambda light chains may point to the presence of light-chain amyloid in their structures.

  3. Exercise motives and positive body image in physically active college women and men: Exploring an expanded acceptance model of intuitive eating.

    Science.gov (United States)

    Tylka, Tracy L; Homan, Kristin J

    2015-09-01

    The acceptance model of intuitive eating posits that body acceptance by others facilitates body appreciation and internal body orientation, which contribute to intuitive eating. Two domains of exercise motives (functional and appearance) may also be linked to these variables, and thus were integrated into the model. The model fit the data well for 406 physically active U.S. college students, although some pathways were stronger for women. Body acceptance by others directly contributed to higher functional exercise motives and indirectly contributed to lower appearance exercise motives through higher internal body orientation. Functional exercise motives positively, and appearance exercise motives inversely, contributed to body appreciation. Whereas body appreciation positively, and appearance exercise motives inversely, contributed to intuitive eating for women, only the latter association was evident for men. To benefit positive body image and intuitive eating, efforts should encourage body acceptance by others and emphasize functional and de-emphasize appearance exercise motives.

  4. Analysis of the Relationship between Physical Self-Concept and Body Image Dissatisfaction in Female Students

    Directory of Open Access Journals (Sweden)

    Sirus Alipoor

    2009-01-01

    Full Text Available Problem statement: Body image is a psychological construct which refers to self-concept including self image and feelings an individual perceives about his or her body. Body image can significantly affect the way an individual perceives about his or her body. Studies on relationship between physical self-concept and body image in some countries showed that the women's body dissatisfaction has led to increase in eating disorders. The question was raised whether such a relationship may exist in Iran. Approach: The purpose of this study was to investigate the relationship between physical self-concept and body Image dissatisfaction in female. The importance of body image in Iranian culture has, recently, became more significant to the extent that tremendous expenditure of time, effort and money has been paid by people, particularly by women, seeking to alert their appearances to resemble an idea image. A survey of 140 female students selected through random sampling was conducted in Shahid Chamran University of Ahvaz, southern Iran. To collect data, a questionnaire including Demographic Information form the Physical Self-Perception Profile (PSPP and Nine Figure Silhouette Scale was used. The physical self-perception profile have five subscales, which were sport competence (SPORT, body attractiveness (BODY, physical condition (CONDITION and physical strength (STRENGTH and one subscale that assesses a global perception of overall Physical Self-Worth (PSW. Results: The finding of the research indicated that there is a significant negative correlation between the physical self-concept and body image dissatisfaction. The correlations magnitude ranged between 0.49-0.79 for body image dissatisfaction. Body image dissatisfaction correlated strongest with physical self-worth and with body physical self-concept in female students in Iran. Thinness had the most influential impact on body image dissatisfaction. The findings also showed discrepancy between the

  5. Impact of body mass index, physical activity, and other clinical factors on cardiorespiratory fitness (from the Cooper Center longitudinal study).

    Science.gov (United States)

    Lakoski, Susan G; Barlow, Carolyn E; Farrell, Stephen W; Berry, Jarett D; Morrow, James R; Haskell, William L

    2011-07-01

    Cardiorespiratory fitness (CRF) is widely accepted as an important reversible cardiovascular risk factor. In the present study, we examined the nonmodifiable and modifiable determinants of CRF within a large healthy Caucasian population of men and women. The study included 20,239 patients presenting to Cooper Clinic (Dallas, Texas) for a comprehensive medical examination from 2000 through 2010. CRF was determined by maximal treadmill exercise testing. Physical activity categories were 0 metabolic equivalent tasks (METs)/min/week (no self-reported moderate or vigorous intensity physical activity), 1 to 449 METs/min/week (not meeting physical activity guideline), 450 to 749 METs/min/week (meeting guideline), and ≥750 METs/min/week (exceeding guideline). Linear regression modeling was used to determine the most robust clinical factors associated with achieved treadmill time. Age, gender, body mass index (BMI), and physical activity were the most important factors associated with CRF, explaining 56% of the variance (R(2) = 0.56). The addition of all other factors combined (current smoking, systolic blood pressure, blood glucose, high-density and low-density lipoprotein cholesterol, health status) were associated with CRF (p physical activity on CRF, such that normal-weight (BMI physical activity compared to obese subjects (BMI ≥30 kg/m(2)). Percent body fat, not lean body mass, was the key factor driving this interaction. In conclusion, BMI was the most important clinical risk factor associated with CRF other than nonmodifiable risk factors age and gender. For a similar amount of physical activity, normal-weight subjects achieved a higher CRF level compared to obese subjects. These data suggest that obesity may offset the benefits of physical activity on achieved CRF, even in a healthy population of men and women.

  6. The Combined Strength of Thermodynamics and Comparative Planetology: Application of Activity Models to Core Formation in Terrestrial Bodies

    Science.gov (United States)

    Righter, K.; Pando, K. M.; Danielson, L. R.

    2015-01-01

    Recent models for accretion of terrestrial bodies involve metal-silicate equilibrium as the metallic core formed during growth. Most elements considered are either refractory or well studied elements for which effects of pressure, temperature, oxygen fugacity, and metallic liquid composition are well known. There are a large number of elements that are both siderophile and volatile, whose fate in such models is unknown, largely due to a lack of data at comparable conditions and com-positions (FeNi core with light elements such as S, C, Si, and O). We have focused on Ge, In, As, Sb and determined the effect of Si and C on metal-silicate partitioning, and developed a thermo-dynamic model that allows application of these new data to a wide range of planetary bodies. New experiments: We have previously carried out experiments with FeSi metallic liquid at C-saturated conditions at 1600 and 1800 C [4]. In a new series of experiments we investigate the effect of Si in carbon-free systems at 1600 C for comparison. Experiments were carried out at 1 GPa in MgO capsules using the same basaltic starting composition as in previous studies. The MgO capsule reacts with the silicate melt to form more MgO-rich liquids that have 22-26 wt% MgO. Experimental met-als and silicates were analyzed using a combination of electron microprobe analysis and laser ablation ICP-MS. Results: The new results can be interpreted by considering Ge as an example, in the simple exchange equilibrium Fe + GeO = FeO + Ge, where the equilibrium constant Kd can be examined as a function of Si content of the metal. The slope of lnKd vs. (1-XSi) for this new series allows derivation of the epsilon interaction parameter for each of these four elements and Si (both C-saturated and C-free).All four elements have positive epsilon values, indicating that Si causes a decrease in the partition coefficients; values are 6.6, 6.5, 27.8 and 25.2 for In, Ge, As, and Sb, respectively, at 1 GPa and 1600 C. As an example of

  7. Development of methods for body composition studies

    Energy Technology Data Exchange (ETDEWEB)

    Mattsson, Soeren [Department of Radiation Physics, Lund University, Malmoe University Hospital, SE-205 02 Malmoe (Sweden); Thomas, Brian J [School of Physical and Chemical Sciences, Queensland University of Technology, Brisbane, QLD 4001 (Australia)

    2006-07-07

    This review is focused on experimental methods for determination of the composition of the human body, its organs and tissues. It summarizes the development and current status of fat determinations from body density, total body water determinations through the dilution technique, whole and partial body potassium measurements for body cell mass estimates, in vivo neutron activation analysis for body protein measurements, dual-energy absorptiometry (DEXA), computed tomography (CT) and magnetic resonance imaging (MRI, fMRI) and spectroscopy (MRS) for body composition studies on tissue and organ levels, as well as single- and multiple-frequency bioimpedance (BIA) and anthropometry as simple easily available methods. Methods for trace element analysis in vivo are also described. Using this wide range of measurement methods, together with gradually improved body composition models, it is now possible to quantify a number of body components and follow their changes in health and disease. (review)

  8. Processing of food, body and emotional stimuli in anorexia nervosa: a systematic review and meta-analysis of functional magnetic resonance imaging studies.

    Science.gov (United States)

    Zhu, Yikang; Hu, Xiaochen; Wang, Jijun; Chen, Jue; Guo, Qian; Li, Chunbo; Enck, Paul

    2012-11-01

    The characteristics of the cognitive processing of food, body and emotional information in patients with anorexia nervosa (AN) are debatable. We reviewed functional magnetic resonance imaging studies to assess whether there were consistent neural basis and networks in the studies to date. Searching PubMed, Ovid, Web of Science, The Cochrane Library and Google Scholar between January 1980 and May 2012, we identified 17 relevant studies. Activation likelihood estimation was used to perform a quantitative meta-analysis of functional magnetic resonance imaging studies. For both food stimuli and body stimuli, AN patients showed increased hemodynamic response in the emotion-related regions (frontal, caudate, uncus, insula and temporal) and decreased activation in the parietal region. Although no robust brain activation has been found in response to emotional stimuli, emotion-related neural networks are involved in the processing of food and body stimuli among AN. It suggests that negative emotional arousal is related to cognitive processing bias of food and body stimuli in AN.

  9. Appraisal of Antioxidant and Anti-Inflammatory Activities of Various Extracts from the Fruiting Bodies of Pleurotus florida

    Directory of Open Access Journals (Sweden)

    Kyung Hoan Im

    2014-03-01

    Full Text Available Pleurotus florida has been widely used for nutritional and medicinal purposes. The present study was conducted to evaluate the antioxidant and anti-inflammatory effects of the fruiting bodies of P. florida extracted with acetone, methanol, and hot water. The antioxidant activities of the acetone and methanol extracts of P. florida showed stronger inhibition of β-carotene-linoleic acid compared to that of the hot water extract. The acetone extract (8 mg/mL showed a high reducing power of 1.86. The acetone and methanol extracts showed more effective DPPH radical scavenging activities than the hot water extract. The chelating effect of the extracts at lower concentrations was significantly effective compared to that of the positive control. Thirteen phenolic compounds were detected from acetonitrile and hydrochloric acid solvent extracts. Nitric oxide (NO production and inducible nitric oxide synthase (iNOS expression in lipolysaccahride (LPS stimulated RAW 264.7 cells, a murine macrophage cell line, were inhibited significantly by the mushroom extracts in a concentration dependent manner. The anti-inflammatory activity on carrageenan-induced edema in the rat hind-paw reduced significantly by the mushroom extracts. Therefore, we have demonstrated that P. florida fruiting bodies possess antioxidant and anti-inflammatory activites related to their inhibitory activities on NO production, iNOS protein expression, and carrageenan-induced paw edema in rats. The results suggest that the fruiting bodies of P. florida are a good source of natural antioxidant and anti-inflammatory agents.

  10. Impact of Different Body Positions on Bioelectrical Activity of the Pelvic Floor Muscles in Nulliparous Continent Women

    Directory of Open Access Journals (Sweden)

    Daria Chmielewska

    2015-01-01

    Full Text Available We examined pelvic floor muscles (PFM activity (%MVC in twenty nulliparous women by body position during exercise as well as the activation of abdominal muscles and the gluteus maximus during voluntary contractions of the PFMs. Pelvic floor muscle activity was recorded using a vaginal probe during five experimental trials. Activation of transversus abdominis, rectus abdominis, and gluteus maximus during voluntary PFM contractions was also assessed. Significant differences in mean normalized amplitudes of baseline PFM activity were revealed between standing and lying (P<0.00024 and lying and ball-sitting positions (P<0.0053. Average peak, average time before peak, and average time after peak did not differ significantly during the voluntary contractions of the PFMs. Baseline PFM activity seemed to depend on the body position and was the highest in standing. Pelvic floor muscles activity during voluntary contractions did not differ by position in continent women. Statistically significant differences between the supine lying and sitting positions were only observed during a sustained 60-second contraction of the PFMs.

  11. Physical activity, fitness and body composition of Finnish police officers: a 15-year follow-up study.

    Science.gov (United States)

    Sörensen, L; Smolander, J; Louhevaara, V; Korhonen, O; Oja, P

    2000-01-01

    This study evaluated changes in the physical activity, fitness and body composition of 103 police officers during a 15-year follow-up. The absolute aerobic capacity was similar in 1981 and 1996, muscular performance had declined, and body weight had increased approximately 0.5 kg/year. More than half the subjects (53%) had increased their leisure-time physical activity in 1996. The correlation was significant between physical activity in 1981 and physical fitness in 1996, but weak between physical activity in 1996 and fitness in 1996. It was also significant between waist circumference and waist/hip ratio in 1996 and physical activity during the previous 5 and 15 years. No significant correlations were found between physical activity and work ability or perceived physical or mental job stress. The physical fitness of middle-aged police officers seems to be predicted strongly by physical activity in early adulthood. Therefore health and fitness promotion measures should start at that time. This, together with regular systematic training, should help to sustain work ability of middle-aged police officers.

  12. Analysis of Body Composition and Food Habits of Spanish Celiac Women.

    Science.gov (United States)

    Churruca, Itziar; Miranda, Jonatan; Lasa, Arrate; Bustamante, María Á; Larretxi, Idoia; Simon, Edurne

    2015-07-08

    The purpose of the present work was both to analyze composition of Spanish celiac women and to study the food habits and gluten-free diet of these celiac patients, in order to determine whether they achieve a balanced and healthy diet as well as to highlight nutritional qualitative and/or quantitative differences. 54 adult celiac women (34 ± 13 years) took part in the six-month study. Height, weight and body composition were measured. An analysis of energy consumption and of the macronutrient distribution of their diet was carried out. Their fulfillment of micronutrient intake recommendations was verified. Participants showed a Body Mass Index of 21.6 ± 2.4 kg/m2. Energy Intake was slightly lower than the Dietary Reference Intakes. Excessive protein apart from over-consumption of fat was observed. More than three quarters of participants consumed meat in excess. Carbohydrate consumption along with that of fiber was below recommended levels. Vitamin D, iron, and iodine had a low percentage of recommendation compliance. In general, participants followed the recommendations of dairy products and fruit intake whereas vegetable consumption was not enough for the vast majority. We conclude that although the diet of celiac women does not differ much from the diet of general population, some considerations, such as reducing fat and protein consumption and increasing fiber intake, must be taken into account.

  13. Analysis of Body Composition and Food Habits of Spanish Celiac Women

    Science.gov (United States)

    Churruca, Itziar; Miranda, Jonatan; Lasa, Arrate; Bustamante, María Á.; Larretxi, Idoia; Simon, Edurne

    2015-01-01

    The purpose of the present work was both to analyze composition of Spanish celiac women and to study the food habits and gluten-free diet of these celiac patients, in order to determine whether they achieve a balanced and healthy diet as well as to highlight nutritional qualitative and/or quantitative differences. 54 adult celiac women (34 ± 13 years) took part in the six-month study. Height, weight and body composition were measured. An analysis of energy consumption and of the macronutrient distribution of their diet was carried out. Their fulfillment of micronutrient intake recommendations was verified. Participants showed a Body Mass Index of 21.6 ± 2.4 kg/m2. Energy Intake was slightly lower than the Dietary Reference Intakes. Excessive protein apart from over-consumption of fat was observed. More than three quarters of participants consumed meat in excess. Carbohydrate consumption along with that of fiber was below recommended levels. Vitamin D, iron, and iodine had a low percentage of recommendation compliance. In general, participants followed the recommendations of dairy products and fruit intake whereas vegetable consumption was not enough for the vast majority. We conclude that although the diet of celiac women does not differ much from the diet of general population, some considerations, such as reducing fat and protein consumption and increasing fiber intake, must be taken into account. PMID:26184289

  14. Analysis of Body Composition and Food Habits of Spanish Celiac Women

    Directory of Open Access Journals (Sweden)

    Itziar Churruca

    2015-07-01

    Full Text Available The purpose of the present work was both to analyze composition of Spanish celiac women and to study the food habits and gluten-free diet of these celiac patients, in order to determine whether they achieve a balanced and healthy diet as well as to highlight nutritional qualitative and/or quantitative differences. 54 adult celiac women (34 ± 13 years took part in the six-month study. Height, weight and body composition were measured. An analysis of energy consumption and of the macronutrient distribution of their diet was carried out. Their fulfillment of micronutrient intake recommendations was verified. Participants showed a Body Mass Index of 21.6 ± 2.4 kg/m2. Energy Intake was slightly lower than the Dietary Reference Intakes. Excessive protein apart from over-consumption of fat was observed. More than three quarters of participants consumed meat in excess. Carbohydrate consumption along with that of fiber was below recommended levels. Vitamin D, iron, and iodine had a low percentage of recommendation compliance. In general, participants followed the recommendations of dairy products and fruit intake whereas vegetable consumption was not enough for the vast majority. We conclude that although the diet of celiac women does not differ much from the diet of general population, some considerations, such as reducing fat and protein consumption and increasing fiber intake, must be taken into account.

  15. Rotational kinematics of a rigid body about a fixed axis: development and analysis of an inventory

    Science.gov (United States)

    Mashood, K. K.; Singh, Vijay A.

    2015-07-01

    We present the development, administration, and analysis of a focused inventory on the rotational kinematics of a rigid body around a fixed axis. The inventory, which is made up of 13 multiple-choice questions, was developed on the basis of interactions with students and teachers. The systematic and iterative aspects of the construction of the inventory are illustrated. The questions, which were validated, were administered to a set of teachers (N = 25) and two groups of preuniversity students (N = 74 and 905) in India. Students, as well as teachers, exhibited difficulties in applying the operational definition of angular velocity to a rigid body. Many erroneously assumed that an angular acceleration cannot exist without a net torque. Patterns of reasoning resulting in errors were identified and categorized under four broad themes. These include inappropriate extensions of familiar procedural practices, reasoning cued by primitive elements in thought, lack of differentiation between related but distinct concepts, and indiscriminate use of equations. The inventory was also administered to introductory-level students (N = 384) at the University of Washington. Popular distractors to most items were similar to the Indian students.

  16. An IMU-to-Body Alignment Method Applied to Human Gait Analysis

    Directory of Open Access Journals (Sweden)

    Laura Susana Vargas-Valencia

    2016-12-01

    Full Text Available This paper presents a novel calibration procedure as a simple, yet powerful, method to place and align inertial sensors with body segments. The calibration can be easily replicated without the need of any additional tools. The proposed method is validated in three different applications: a computer mathematical simulation; a simplified joint composed of two semi-spheres interconnected by a universal goniometer; and a real gait test with five able-bodied subjects. Simulation results demonstrate that, after the calibration method is applied, the joint angles are correctly measured independently of previous sensor placement on the joint, thus validating the proposed procedure. In the cases of a simplified joint and a real gait test with human volunteers, the method also performs correctly, although secondary plane errors appear when compared with the simulation results. We believe that such errors are caused by limitations of the current inertial measurement unit (IMU technology and fusion algorithms. In conclusion, the presented calibration procedure is an interesting option to solve the alignment problem when using IMUs for gait analysis.

  17. Comparative Analysis of the Current Status, Own Body Perception and Positive Experience From Diagnosed Breast Cancer

    Directory of Open Access Journals (Sweden)

    Zornitza Ganeva

    2013-04-01

    Full Text Available Comparative analysis of the current status, own body perception and positive experience within a period of up to 1 year from diagnosing ofwomen with breast cancer (N = 41; mean age 35.25 in the 1st, 2nd and 3rd stages of the disease progress, of Bulgarian origin, was made.Reliability and validity of the scales were described. They were analysed with respect to: 1 medical characteristics (partial or total surgery,surgical removal of lymph nodes, presence or absence of metastases in them, 2 classical therapies (chemotherapy, radiation therapy andhormonal therapy administered or not and 3 application or not of alternative therapies (herbal medicine, physical load, administration ofmassage, lymph drainage, use of nutritional supplements, observance of diet. The results showed that the more therapies the personssurveyed were undergone the more unsatisfactory they assessed their current general status. The bigger the size of the surgery performedto remove the tumour the more positive idea of their own bodies they had. The more time after the surgical treatment passed the more thepositive experience accumulated from the oncologic diagnosis grew.

  18. Granules Harboring Translationally Active mRNAs Provide a Platform for P-Body Formation following Stress

    Directory of Open Access Journals (Sweden)

    Jennifer Lui

    2014-11-01

    Full Text Available The localization of mRNA to defined cytoplasmic sites in eukaryotic cells not only allows localized protein production but also determines the fate of mRNAs. For instance, translationally repressed mRNAs localize to P-bodies and stress granules where their decay and storage, respectively, are directed. Here, we find that several mRNAs are localized to granules in unstressed, actively growing cells. These granules play a key role in the stress-dependent formation of P-bodies. Specific glycolytic mRNAs are colocalized in multiple granules per cell, which aggregate during P-body formation. Such aggregation is still observed under conditions or in mutants where P-bodies do not form. In unstressed cells, the mRNA granules appear associated with active translation; this might enable a coregulation of protein expression from the same pathways or complexes. Parallels can be drawn between this coregulation and the advantage of operons in prokaryotic systems.

  19. Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis

    Science.gov (United States)

    de Blasio, Francesca; de Blasio, Francesco; Miracco Berlingieri, Giulia; Bianco, Andrea; La Greca, Marta; Franssen, Frits M E; Scalfi, Luca

    2016-01-01

    Background Multifrequency bioelectrical impedance analysis (MF-BIA) is a technique that measures body impedance (Z) at different frequencies (5, 10, 50, 100, and 250 kHz). Body composition may be estimated using empirical equations, which include BIA variables or, alternatively, raw BIA data may provide direct information on water distribution and muscle quality. Objectives To compare raw MF-BIA data between COPD patients and controls and to study their relationship with respiratory and functional parameters in COPD patients. Methods MF-BIA was performed (Human Im-Touch analyzer) in 212 COPD patients and 115 age- and BMI-matched controls. Fat-free mass (FFM) and fat mass were estimated from BIA data, and low- to high-frequency (5 kHz/250 kHz) impedance ratio was calculated. Physical fitness, lung function and respiratory muscle strength were also assessed in COPD patients. Results After adjusting for age, weight, and body mass index, FFM and the 5/250 impedance ratio were lower in COPD patients (P<0.001) and were negatively affected by disease severity. In both male and female patients, the 5/250 impedance ratio was significantly correlated mainly with age (r=−0.316 and r=−0.346, respectively). Patients with a 5/250 impedance ratio below median value had lower handgrip strength (P<0.001), 6-minute walk distance (P<0.005), respiratory muscle strength (P<0.005), forced expiratory volume in 1 second (P<0.05) and vital capacity (P<0.005). Finally, the 5/250 impedance ratio was reduced (P<0.05) in patients with Global Initiative for Chronic Obstructive Lung Disease (GOLD) III and IV (compared to those with GOLD I and II) or a BODE index between 6 and 10 points (compared to those with BODE index between 1 and 5 points). Conclusion MF-BIA may be a useful tool for assessing body composition and nutritional status in COPD patients. In particular, the impedance ratio could give valuable information on cellular integrity and muscle quality.

  20. Bones, body parts, and sex appeal: An analysis of #thinspiration images on popular social media.

    Science.gov (United States)

    Ghaznavi, Jannath; Taylor, Laramie D

    2015-06-01

    The present study extends research on thinspiration images, visual and/or textual images intended to inspire weight loss, from pro-eating disorder websites to popular photo-sharing social media websites. The article reports on a systematic content analysis of thinspiration images (N=300) on Twitter and Pinterest. Images tended to be sexually suggestive and objectifying with a focus on ultra-thin, bony, scantily-clad women. Results indicated that particular social media channels and labels (i.e., tags) were characterized by more segmented, bony content and greater social endorsement compared to others. In light of theories of media influence, results offer insight into the potentially harmful effects of exposure to sexually suggestive and objectifying content in large online communities on body image, quality of life, and mental health.

  1. Using frequency analysis to improve the precision of human body posture algorithms based on Kalman filters.

    Science.gov (United States)

    Olivares, Alberto; Górriz, J M; Ramírez, J; Olivares, G

    2016-05-01

    With the advent of miniaturized inertial sensors many systems have been developed within the last decade to study and analyze human motion and posture, specially in the medical field. Data measured by the sensors are usually processed by algorithms based on Kalman Filters in order to estimate the orientation of the body parts under study. These filters traditionally include fixed parameters, such as the process and observation noise variances, whose value has large influence in the overall performance. It has been demonstrated that the optimal value of these parameters differs considerably for different motion intensities. Therefore, in this work, we show that, by applying frequency analysis to determine motion intensity, and varying the formerly fixed parameters accordingly, the overall precision of orientation estimation algorithms can be improved, therefore providing physicians with reliable objective data they can use in their daily practice.

  2. Experimental and theoretical analysis of vortex breakdown in the wake of the 25∘ Ahmed body

    Science.gov (United States)

    Jermann, Cyril; Meliga, Philippe; Pujals, Gregory; Gallaire, Francois; Serre, Eric

    2014-11-01

    We study experimentally and theoretically the wake of the 25circ; Ahmed body, considered a suitable test-case to reproduce the two counter-rotating longitudinal vortices widely encountered in automotive aerodynamics. The three-dimensional experimental mean flow is reconstructed at high Reynolds number (Re = 2 . 8 ×106) from a series of cross-flow time-averaged planes acquired with a moving automated Stereo-PIV system. We observe a sharp decay of the axial velocity and vorticity in the near-wake, 0 . 5 times the projected length of the slanted surface downstream the square back, where the streamwise vortices is subjected to a strong adverse pressure gradient and the turbulent kinetic energy exhibits a peak in the vortex core. A stability analysis of the experimental velocity shows that the flow undergoes vortex breakdown roughly at the same position, through a transition from supercritical (x 0 . 5) conditions and the accumulation of upstream propagating axisymmetric waves.

  3. High-Speed Linear Raman Spectroscopy for Instability Analysis of a Bluff Body Flame

    Science.gov (United States)

    Kojima, Jun; Fischer, David

    2013-01-01

    We report a high-speed laser diagnostics technique based on point-wise linear Raman spectroscopy for measuring the frequency content of a CH4-air premixed flame stabilized behind a circular bluff body. The technique, which primarily employs a Nd:YLF pulsed laser and a fast image-intensified CCD camera, successfully measures the time evolution of scalar parameters (N2, O2, CH4, and H2O) in the vortex-induced flame instability at a data rate of 1 kHz. Oscillation of the V-shaped flame front is quantified through frequency analysis of the combustion species data and their correlations. This technique promises to be a useful diagnostics tool for combustion instability studies.

  4. Pediatric body composition analysis with dual-energy X-ray absorptiometry

    Energy Technology Data Exchange (ETDEWEB)

    Helba, Maura; Binkovitz, Larry A. [Nationwide Children' s Hospital, Department of Radiology, Columbus, OH (United States)

    2009-07-15

    Pediatric applications of body composition analysis (BCA) have become of increased interest to pediatricians and other specialists. With the increasing prevalence of morbid obesity and with an increased awareness of anorexia nervosa, pediatric specialists are utilizing BCA data to help identify, treat, and prevent these conditions. Dual-energy X-ray absorptiometry (DXA) can be used to determine the fat mass (FM) and lean tissue mass (LTM), as well as bone mineral content (BMC). Among the readily available BCA techniques, DXA is the most widely used and it has the additional benefit of precisely quantifying regional FM and LTM. This review evaluates the strengths and limitations of DXA as a pediatric BCA method and considers the utilization of DXA to identify trends and variations in FM and LTM measurements in obese and anorexic children. (orig.)

  5. Using Multimodal Learning Analytics to Identify Patterns of Interactions in a Body-Based Mathematics Activity

    Science.gov (United States)

    Smith, Carmen; King, Barbara; Gonzalez, Diana

    2016-01-01

    Elementary students' difficulties with angles in geometry are well documented, but we know little about how they conceptualize angles while solving problems and how their thinking changes over time. In this study, we examined 26 third and fourth grade students completing a body-based angle task supported by the Kinect for Windows. We used…

  6. Increase in vagal activity during hypotensive lower-body negative pressure in humans

    DEFF Research Database (Denmark)

    Sander-Jensen, K; Mehlsen, J; Stadeager, C

    1988-01-01

    Progressive central hypovolemia is characterized by a normotensive, tachycardic stage followed by a reversible, hypotensive stage with slowing of the heart rate (HR). We investigated circulatory changes and arterial hormone concentrations in response to lower-body negative pressure (LBNP) in six ...

  7. Simultaneous collection of body temperature and activity data in burrowing mammals : a new technique

    NARCIS (Netherlands)

    Long, Ryan A.; Hut, Roelof A.; Barnes, Brian M.

    2007-01-01

    Integrating physiological and behavioral observations into ecological field studies of animals can provide novel insights into relationships among animal behavior, physiology, and ecology. We describe and evaluate a new technique for simultaneously collecting body temperature (T-b) and burrow use da

  8. Temporal phasing of locomotor activity, heart rate rhythmicity, and core body temperature is disrupted in VIP receptor 2-deficient mice.

    Science.gov (United States)

    Hannibal, Jens; Hsiung, Hansen M; Fahrenkrug, Jan

    2011-03-01

    Neurons of the brain's biological clock located in the hypothalamic suprachiasmatic nucleus (SCN) generate circadian rhythms of physiology (core body temperature, hormone secretion, locomotor activity, sleep/wake, and heart rate) with distinct temporal phasing when entrained by the light/dark (LD) cycle. The neuropeptide vasoactive intestinal polypetide (VIP) and its receptor (VPAC2) are highly expressed in the SCN. Recent studies indicate that VIPergic signaling plays an essential role in the maintenance of ongoing circadian rhythmicity by synchronizing SCN cells and by maintaining rhythmicity within individual neurons. To further increase the understanding of the role of VPAC2 signaling in circadian regulation, we implanted telemetric devices and simultaneously measured core body temperature, spontaneous activity, and heart rate in a strain of VPAC2-deficient mice and compared these observations with observations made from mice examined by wheel-running activity. The study demonstrates that VPAC2 signaling is necessary for a functional circadian clock driving locomotor activity, core body temperature, and heart rate rhythmicity, since VPAC2-deficient mice lose the rhythms in all three parameters when placed under constant conditions (of either light or darkness). Furthermore, although 24-h rhythms for three parameters are retained in VPAC2-deficient mice during the LD cycle, the temperature rhythm displays markedly altered time course and profile, rising earlier and peaking ∼4-6 h prior to that of wild-type mice. The use of telemetric devices to measure circadian locomotor activity, temperature, and heart rate, together with the classical determination of circadian rhythms of wheel-running activity, raises questions about how representative wheel-running activity may be of other behavioral parameters, especially when animals have altered circadian phenotype.

  9. Temporal phasing of locomotor activity, heart rate rhythmicity, and core body temperature is disrupted in VIP receptor 2-deficient mice

    DEFF Research Database (Denmark)

    Hannibal, Jens; Hsiung, Hansen M; Fahrenkrug, Jan

    2011-01-01

    ) cycle. The neuropeptide vasoactive intestinal polypetide (VIP) and its receptor (VPAC2) are highly expressed in the SCN. Recent studies indicate that VIPergic signaling plays an essential role in the maintenance of ongoing circadian rhythmicity by synchronizing SCN cells and by maintaining rhythmicity......Neurons of the brain's biological clock located in the hypothalamic suprachiasmatic nucleus (SCN) generate circadian rhythms of physiology (core body temperature, hormone secretion, locomotor activity, sleep/wake, and heart rate) with distinct temporal phasing when entrained by the light/dark (LD...... within individual neurons. To further increase the understanding of the role of VPAC2 signaling in circadian regulation, we implanted telemetric devices and simultaneously measured core body temperature, spontaneous activity, and heart rate in a strain of VPAC2-deficient mice and compared...

  10. Hybrid-Wing-Body Vehicle Composite Fuselage Analysis and Case Study

    Science.gov (United States)

    Mukhopadhyay, Vivek

    2014-01-01

    Recent progress in the structural analysis of a Hybrid Wing-Body (HWB) fuselage concept is presented with the objective of structural weight reduction under a set of critical design loads. This pressurized efficient HWB fuselage design is presently being investigated by the NASA Environmentally Responsible Aviation (ERA) project in collaboration with the Boeing Company, Huntington Beach. The Pultruded Rod-Stiffened Efficient Unitized Structure (PRSEUS) composite concept, developed at the Boeing Company, is approximately modeled for an analytical study and finite element analysis. Stiffened plate linear theories are employed for a parametric case study. Maximum deflection and stress levels are obtained with appropriate assumptions for a set of feasible stiffened panel configurations. An analytical parametric case study is presented to examine the effects of discrete stiffener spacing and skin thickness on structural weight, deflection and stress. A finite-element model (FEM) of an integrated fuselage section with bulkhead is developed for an independent assessment. Stress analysis and scenario based case studies are conducted for design improvement. The FEM model specific weight of the improved fuselage concept is computed and compared to previous studies, in order to assess the relative weight/strength advantages of this advanced composite airframe technology

  11. Halo statistics analysis within medium volume cosmological N-body simulation

    Directory of Open Access Journals (Sweden)

    Martinović N.

    2015-01-01

    Full Text Available In this paper we present halo statistics analysis of a ΛCDM N body cosmological simulation (from first halo formation until z = 0. We study mean major merger rate as a function of time, where for time we consider both per redshift and per Gyr dependence. For latter we find that it scales as the well known power law (1 + zn for which we obtain n = 2.4. The halo mass function and halo growth function are derived and compared both with analytical and empirical fits. We analyse halo growth through out entire simulation, making it possible to continuously monitor evolution of halo number density within given mass ranges. The halo formation redshift is studied exploring possibility for a new simple preliminary analysis during the simulation run. Visualization of the simulation is portrayed as well. At redshifts z = 0−7 halos from simulation have good statistics for further analysis especially in mass range of 1011 − 1014 M./h. [176021 ’Visible and invisible matter in nearby galaxies: theory and observations

  12. Analysis of land use changes near large water bodies in Ukraine using GIS.

    Science.gov (United States)

    Bogdanets, Vyacheslav; Vlaev, Anatoliy

    2015-01-01

    Analysis of land use and land cover changes in Ukraine were evaluated with special attention given to the interaction of land and water resources. The rational fresh water management in agriculture under future climate change conditions is of great importance. The hydrological regime of a river has huge impact on the environment of the surrounding area. Creating reservoirs, changes the landscape of river valleys and lake basins. Changes in the hydrological regime of the river and the process taking place in the coastal zone are reflected in land cover, wildlife and micro-climatic conditions. In the area closer to the shore line of the reservoir, there is greater amplitude of fluctuations in the level of ground water due to low rate of filtration behind fluctuations in the level of the reservoir. The interaction of water reservoirs with the environment, especially with the nature of the catchment area is substantially different from the natural water bodies. Analysis was done using GIS and remotely sensed data of land use near large water reservoirs and processed statistically. The ratio of arable lands and forested territories and future analysis of land use has been discussed.

  13. Association between body mass index and erosive esophagitis: A meta-analysis

    Institute of Scientific and Technical Information of China (English)

    Nan Cai; Guo-Zhong Ji; Zhi-Ning Fan; Yan-Feng Wu; Fa-Ming Zhang; Zhi-Fei Zhao; Wei Xu; Zheng Liu

    2012-01-01

    AIM:To conduct a meta-analysis to estimate the determinants of the association between erosive esophagitis (EE) and body mass index (BMI).METHODS:We identified the studies using PubMed.Studies were selected for analysis based on certain inclusion and exclusion criteria.Data were extracted from each study on the basis of predefined items.Metaanalyses were performed to verify the risk factors,such as obesity and gender.RESULTS:Twenty-one studies were included in this systematic review.These studies demonstrated an association between increasing BMI and the presence of EE [95% confidence interval (CI):1.35-1.88,overweight,odds ratio (OR) =1.60,P value homogeneity 0.003,95% CI:1.65-2.55,obese,OR =2.05,P <0.01].The heterogeneity disappeared by stratifying for gender.No publication bias was observed in this metaanalysis by the Egger method.CONCLUSION:This analysis demonstrates a positive association between BMI and the presence of EE,especially in males.The risk seems to progressively increase with increasing weight.

  14. Maternal Body Mass Index and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis

    Science.gov (United States)

    Wang, Ying; Tang, Shiming; Xu, Shunsheng; Weng, Shenhong; Liu, Zhongchun

    2016-01-01

    Controversial results of the association between maternal body mass index (BMI) and risk of autism spectrum disorder (ASD) in offspring were reported among several studies. This meta-analysis was conducted to estimate the overall association between maternal BMI and risk of ASD in offspring. PubMed, EMBASE, Web of Science, and the Cochrane Library were searched until January 2016. Cohort and case-control studies addressing the association between maternal BMI and risk of ASD in offspring were included. We used random-effect models to estimate the summary relative risks (RRs), we also performed a dose-response meta-analysis to estimate the trend from the correlated log RR estimates across levels of BMI quantitatively. Totally, 6 cohort studies and 1 case-control study involving 8,403 cases and 509,167 participants were included for analysis. The summary RR (95% confidence interval) for ASD in offspring in relation to maternal underweight, overweight, and obesity vs. normal weight during pre-pregnancy or pregnancy, was 1.07 (0.93, 1.23), 1.28 (1.19, 1.36) and 1.36 (1.03, 1.78), respectively. A linear dose-response relationship was found, with a pooled RR of 1.16 (1.01, 1.33) for each 5 kg/m2. increment in maternal BMI. The present study suggests that excessive maternal BMI is associated with increased ASD risk in offspring. PMID:27687989

  15. Hydrogen sulfide activates the carotid body chemoreceptors in cat, rabbit and rat ex vivo preparations.

    Science.gov (United States)

    Jiao, Yingfu; Li, Qian; Sun, Biying; Zhang, Guohua; Rong, Weifang

    2015-03-01

    We and others previously reported experimental evidence suggesting an important role for hydrogen sulfide (H2S) in oxygen sensing in murine carotid body chemoreceptors. More recent data implicated abnormal H2S-mediated chemoreceptor signaling in pathological conditions such as chronic heart failure and hypertension. However, the idea of H2S as a mediator of oxygen-sensing in chemoreceptors has been challenged. In particular, it was shown that exogenous H2S inhibited the release of neurotransmitters (ACh and ATP) from the cat carotid body, raising the possibility that there exists significant species difference in H2S-mediated signaling in chemoreceptors. This study was designed specifically to determine the effect of H2S on chemoreceptors in different species. We conducted multiunit extracellular recordings of the sinus nerve in the ex vivo carotid body preparation taken from the rat, the cat and the rabbit. As observed in the mouse carotid body, H2S donors (NaHS or Na2S) evoked qualitatively similar excitatory responses of the afferent sinus nerves of the species studied here. The excitatory effects of the H2S donors were concentration-dependent and reversible. The sinus nerve responses to H2S donors were prevented by blockade of the transmission between type I cells and the afferent terminals, as was the response to hypoxia. These results demonstrate that exogenous H2S exerts qualitatively similar excitatory effects on chemoreceptor afferents of different species. The role of endogenous H2S-mediated signaling in carotid body function in different species awaits further investigation.

  16. Body weight management effect of burdock (Arctium lappa L.) root is associated with the activation of AMP-activated protein kinase in human HepG2 cells.

    Science.gov (United States)

    Kuo, Daih-Huang; Hung, Ming-Chi; Hung, Chao-Ming; Liu, Li-Min; Chen, Fu-An; Shieh, Po-Chuen; Ho, Chi-Tang; Way, Tzong-Der

    2012-10-01

    Burdock (Arcticum lappa L.) root is used in folk medicine and also as a vegetable in Asian countries. In the present study, burdock root treatment significantly reduced body weight in rats. To evaluate the bioactive compounds, we successively extracted the burdock root with ethanol (AL-1), and fractionated it with n-hexane (AL-2), ethyl acetate (AL-3), n-butanol (AL-4), and water (AL-5). Among these fractions, AL-2 contained components with the most effective hypolipidemic potential in human hepatoma HepG2 cells. AL-2 decreased the expression of fatty acid synthase (FASN) and inhibited the activity of acetyl-coenzyme A carboxylase (ACC) by stimulating AMP-activated protein kinase (AMPK) through the LKB1 pathway. Three active compounds were identified from the AL-2, namely α-linolenic acid, methyl α-linolenate, and methyl oleate. These results suggest that burdock root is expected to be useful for body weight management.

  17. Outcomes for Spine Stereotactic Body Radiation Therapy and an Analysis of Predictors of Local Recurrence

    Energy Technology Data Exchange (ETDEWEB)

    Bishop, Andrew J.; Tao, Randa [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Rebueno, Neal C. [Department of Radiation Dosimetry, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Christensen, Eva N.; Allen, Pamela K. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wang, Xin A. [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Amini, Behrang [Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Tannir, Nizar M. [Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Tatsui, Claudio E.; Rhines, Laurence D. [Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li, Jing [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chang, Eric L. [Department of Radiation Oncology, USC Norris Cancer Hospital, Keck School of Medicine of USC, Los Angeles, California (United States); Brown, Paul D. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Ghia, Amol J., E-mail: ajghia@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2015-08-01

    Purpose: To investigate local control, survival outcomes, and predictors of local relapse for patients treated with spine stereotactic body radiation therapy. Methods and Materials: We reviewed the records of 332 spinal metastases consecutively treated with stereotactic body radiation therapy between 2002 and 2012. The median follow-up for all living patients was 33 months (range, 0-111 months). Endpoints were overall survival and local control (LC); recurrences were classified as either in-field or marginal. Results: The 1-year actuarial LC and overall survival rates were 88% and 64%, respectively. Patients with local relapses had poorer dosimetric coverage of the gross tumor volume (GTV) compared with patients without recurrence (minimum dose [Dmin] biologically equivalent dose [BED] 23.9 vs 35.1 Gy, P<.001; D98 BED 41.8 vs 48.1 Gy, P=.001; D95 BED 47.2 vs 50.5 Gy, P=.004). Furthermore, patients with marginal recurrences had poorer prescription coverage of the GTV (86% vs 93%, P=.01) compared with those with in-field recurrences, potentially because of more upfront spinal canal disease (78% vs 24%, P=.001). Using a Cox regression univariate analysis, patients with a GTV BED Dmin ≥33.4 Gy (median dose) (equivalent to 14 Gy in 1 fraction) had a significantly higher 1-year LC rate (94% vs 80%, P=.001) compared with patients with a lower GTV BED Dmin; this factor was the only significant variable on multivariate Cox analysis associated with LC (P=.001, hazard ratio 0.29, 95% confidence interval 0.14-0.60) and also was the only variable significant in a separate competing risk multivariate model (P=.001, hazard ratio 0.30, 95% confidence interval 0.15-0.62). Conclusions: Stereotactic body radiation therapy offers durable control for spinal metastases, but there is a subset of patients that recur locally. Patients with local relapse had significantly poorer tumor coverage, which was likely attributable to treatment planning directives that prioritized the

  18. Body size, physical activity and risk of colorectal cancer with or without the CpG island methylator phenotype (CIMP.

    Directory of Open Access Journals (Sweden)

    Laura A E Hughes

    Full Text Available BACKGROUND: We investigated how body size and physical activity influence the risk of the CpG island methylator phenotype (CIMP in colorectal cancer (CRC. METHODS: In the Netherlands Cohort Study (n = 120,852, risk factors were self-reported at baseline in 1986. After 7.3 years of follow-up, 603 cases and 4,631 sub-cohort members were available. CIMP status according to the Weisenberger markers was determined using methylation specific PCR on DNA from paraffin embedded tumor tissue. Hazard rate ratios (HR and 95% confidence intervals for CIMP (27.7% and non-CIMP (72.3% tumors were calculated according to BMI, BMI at age 20, BMI change, trouser/skirt size, height, and physical activity. RESULTS: BMI modeled per 5 kg/m(2 increase was associated with both CIMP and non-CIMP tumors, however, HRs were attenuated when additionally adjusted for trouser/skirt size. Trouser/skirt size, per 2 size increase, was associated with both tumor subtypes, even after adjustment for BMI (CIMP HR: 1.20, 95%CI: 1.01-1.43; non-CIMP HR: 1.14, 95%CI: 1.04-1.28. Height per 5 cm was associated with both tumor sub-types, but HRs were attenuated when adjusted for body weight. BMI at age 20 was positively associated with increased risk of CIMP tumors and the association was significantly less pronounced for non-CIMP tumors (P-heterogeneity = 0.01. Physical activity was inversely associated with both subtypes, but a dose-response association was observed only for non-CIMP tumors (P-trend = 0.02. CONCLUSIONS: Body size, especially central adiposity, may increase the risk of both CIMP and non-CIMP tumors. Body fat at young age may differentially influence risk. Physical activity appears to decrease the risk of CRC regardless of these molecular subtypes.

  19. Lewy Body Disease

    Science.gov (United States)

    Lewy body disease is one of the most common causes of dementia in the elderly. Dementia is the loss ... enough to affect normal activities and relationships. Lewy body disease happens when abnormal structures, called Lewy bodies, ...

  20. Constructing the 'gender-specific body': A critical discourse analysis of publications in the field of gender-specific medicine.

    Science.gov (United States)

    Annandale, Ellen; Hammarström, Anne

    2011-11-01

    Gender-specific medicine, a new and increasingly influential ethos within medical research and practice, has received little critical attention to date. The objective of this article is to critically examine the attributes of gender-specific medicine as imparted by its advocates. Through a critical discourse analysis of its two leading academic journals, we identify five interrelated discourses: of male/female difference; of hegemonic biology; of men's disadvantages; of biological and social reductionism; and of the fragmented body. Together these comprise a master discourse of the 'gender-specific body'. The discourse of the 'gender-specific body' is discussed in relation to the current neoliberal political agenda which frames healthcare as a market good and locates health and illness in individual bodies rather than in the wider social arrangements of society. We argue that the 'gender-specific body' threatens not only to turn back the clock to a vision of the biological body as fixed and determinate, but to extend this ever deeper into the social imagination. Lost in the process is any meaningful sense of the human body as a relatively open system which develops in interaction with its social world. We propose that, as it gains momentum, the 'gender-specific body' is likely progressively to circumscribe our thinking about the health of women and men in potentially problematic ways.

  1. TIMED: a computer program for calculating cumulated activity of a radionuclide in the organs of the human body at a given time, t, after deposition

    Energy Technology Data Exchange (ETDEWEB)

    Watson, S.B.; Snyder, W.S.; Ford, M.R.

    1976-12-01

    TIMED is a computer program designed to calculate cumulated radioactivity in the various source organs at various times after radionuclide deposition. TIMED embodies a system of differential equations which describes activity transfer in the lungs, gastrointestinal tract, and other organs of the body. This system accounts for delay of transfer of activity between compartments of the body and radioactive daughters.

  2. Effect of dietary genistein on growth performance, digestive enzyme activity, and body composition of Nile tilapia Oreochromis niloticus

    Science.gov (United States)

    Chen, Dong; Wang, Wei; Ru, Shaoguo

    2015-01-01

    An 8-week feeding experiment was performed to evaluate the effect of dietary genistein on growth performance, body composition, and digestive enzymes activity of juvenile Nile tilapia ( Oreochromis niloticus). Four isonitrogenous and isoenergetic diets were formulated containing four graded supplements of genistein: 0, 30, 300, and 3 000 μg/g. Each diet was randomly assigned in triplicate to tanks stocked with 15 juvenile tilapia (10.47±1.24 g). The results show that 30 and 300 μg/g dietary genistein had no significant effect on growth performance of Nile tilapia, but the higher level of genistein (3 000 μg/g) significantly depressed the final body weight and specific growth rate. There was no significant difference in survival rate, feed intake, feed efficiency ratio or whole body composition among all dietary treatments. An assay of digestive enzymes showed that the diet containing 3 000 μg/ggenistein decreased stomach and hepatopancreas protease activity, and amylase activity in the liver and intestine, while a dietary level of 300 μg/g genistein depressed stomach protease and intestine amylase activities. However, no significant difference in stomach amylase activity was found among dietary treatments. Overall, the results of the present study indicate that a high level of dietary genistein (3 000 μg/g, or above) would significantly reduce the growth of Nile tilapia, partly because of its inhibitory effect on the activity of major digestive enzymes. Accordingly, the detrimental effects of genistein, as found in soybean products, should not be ignored when applied as an alternative ingredient source in aquaculture.

  3. In Vivo Analysis of Cajal Body Movement, Separation, and Joining in Live Human Cells

    OpenAIRE

    Platani, Melpomeni; Goldberg, Ilya; Swedlow, Jason R.; Lamond, Angus I.

    2000-01-01

    Cajal bodies (also known as coiled bodies) are subnuclear organelles that contain specific nuclear antigens, including splicing small nuclear ribonucleoproteins (snRNPs) and a subset of nucleolar proteins. Cajal bodies are localized in the nucleoplasm and are often found at the nucleolar periphery. We have constructed a stable HeLa cell line, HeLaGFP-coilin, that expresses the Cajal body marker protein, p80 coilin, fused to the green fluorescent protein (GFP-coilin). The localization pattern ...

  4. The Influence of Fashion Magazines on the Body Image Satisfaction of College Women: An Exploratory Analysis.

    Science.gov (United States)

    Turner, Sherry L.; Hamilton, Heather; Jacobs, Meija; Angood, Laurie M.; Dwyer, Deanne Hovde

    1997-01-01

    Examines the impact of exposure to fashion magazines on women's (n=24) body image satisfaction. Results indicate that women who viewed fashion magazines prior to completing a body image satisfaction survey, preferred to weigh less, and were less satisfied with their bodies, than peers (n=15) who read news magazines before the survey. (RJM)

  5. In vivo analysis of Cajal body movement, separation, and joining in live human cells.

    Science.gov (United States)

    Platani, M; Goldberg, I; Swedlow, J R; Lamond, A I

    2000-12-25

    Cajal bodies (also known as coiled bodies) are subnuclear organelles that contain specific nuclear antigens, including splicing small nuclear ribonucleoproteins (snRNPs) and a subset of nucleolar proteins. Cajal bodies are localized in the nucleoplasm and are often found at the nucleolar periphery. We have constructed a stable HeLa cell line, HeLa(GFP-coilin), that expresses the Cajal body marker protein, p80 coilin, fused to the green fluorescent protein (GFP-coilin). The localization pattern and biochemical properties of the GFP-coilin fusion protein are identical to the endogenous p80 coilin. Time-lapse recordings on 63 nuclei of HeLa(GFP-coilin) cells showed that all Cajal bodies move within the nucleoplasm. Movements included translocations through the nucleoplasm, joining of bodies to form larger structures, and separation of smaller bodies from larger Cajal bodies. Also, we observed Cajal bodies moving to and from nucleoli. The data suggest that there may be at least two classes of Cajal bodies that differ in their size, antigen composition, and dynamic behavior. The smaller size class shows more frequent and faster rates of movement, up to 0.9 microm/min. The GFP-coilin protein is dynamically associated with Cajal bodies as shown by changes in their fluorescence intensity over time. This study reveals an unexpectedly high level of movement and interactions of nuclear bodies in human cells and suggests that these movements may be driven, at least in part, by regulated mechanisms.

  6. Exergy Analysis of Human Respiration Under Physical Activity

    Directory of Open Access Journals (Sweden)

    Jurandir Itizo Yanagihara

    2010-09-01

    Full Text Available

    This paper presents an exergy analysis of the human body under physical activity. A model of the respiratory system and a model of the thermal system were used for this purpose. These models consider heat and mass transfers in lungs, tissues and blood. Each component of these models is represented by a uniform compartment governed by equations for diffusion, convection, O2 consumption, CO2/heat generation and heat and mass transfer with the environment. The models allow the calculation of the exergy destruction in the lung and tissues, and the contribution of each entropy generation mechanism in the total generation. Furthermore, a discussion is proposed regarding the efficiency of the human body under physical exercise.

  7. Non-verbal Full Body Emotional and Social Interaction: A Case Study on Multimedia Systems for Active Music Listening

    Science.gov (United States)

    Camurri, Antonio

    Research on HCI and multimedia systems for art and entertainment based on non-verbal, full-body, emotional and social interaction is the main topic of this paper. A short review of previous research projects in this area at our centre are presented, to introduce the main issues discussed in the paper. In particular, a case study based on novel paradigms of social active music listening is presented. Active music listening experience enables users to dynamically mould expressive performance of music and of audiovisual content. This research is partially supported by the 7FP EU-ICT Project SAME (Sound and Music for Everyone, Everyday, Everywhere, Every Way, www.sameproject.eu).

  8. Body-selective areas in the visual cortex are less active in children than in adults

    OpenAIRE

    Paddy D Ross; de Gelder, Beatrice; Crabbe, Frances; Grosbras, Marie-Helene

    2014-01-01

    Our ability to read other people’s non-verbal signals gets refined throughout childhood and adolescence. How this is paralleled by brain development has been investigated mainly with regards to face perception, showing a protracted functional development of the face-selective visual cortical areas. In view of the importance of whole-body expressions in interpersonal communication it is important to understand the development of brain areas sensitive to these social signals. Here we used funct...

  9. Comparison of body-powered voluntary opening and voluntary closing prehensor for activities of daily life

    OpenAIRE

    Kelsey Berning; Sarah Cohick; Reva Johnson, MS; Laura Ann Miller, PhD, CP; Jonathon W. Sensinger, PhD

    2014-01-01

    Persons with an upper-limb amputation who use a body-powered prosthesis typically control the prehensor through contralateral shoulder movement, which is transmitted through a Bowden cable. Increased cable tension either opens or closes the prehensor; when tension is released, some passive element, such as a spring, returns the prehensor to the default state (closed or open). In this study, we used the Southampton Hand Assessment Procedure to examine functional differences between these two t...

  10. Collection and analysis of active particles

    Energy Technology Data Exchange (ETDEWEB)

    DeLong, C.W.

    1950-01-27

    When it became apparent that particles were emanating from the stacks of the separations plants, it become important that the source, size, activity and composition of the particles be determined in order to evaluate the hazard to persons working in and neer the stack areas. The present report will give the results of radiochemical analysis of particles collected by electrostatic precipitation from ``B`` plant canyon ventilation air, not from the off-gas ventilation line. Of importance is the fact the particles analyzed consist not only of particles from the ventilation air but also, unavoidably, of rust from the iron manifold used to conduct the gases to the precipitator. This makes a determination of the activity versus weight ratio impossible, but should not invalidate the radiochemical data.

  11. Locatable-body temperature monitoring based on semi-active UHF RFID tags.

    Science.gov (United States)

    Liu, Guangwei; Mao, Luhong; Chen, Liying; Xie, Sheng

    2014-03-26

    This paper presents the use of radio-frequency identification (RFID) technology for the real-time remote monitoring of body temperature, while an associated program can determine the location of the body carrying the respective sensor. The RFID chip's internal integrated temperature sensor is used for both the human-body temperature detection and as a measurement device, while using radio-frequency communication to broadcast the temperature information. The adopted RFID location technology makes use of reference tags together with a nearest neighbor localization algorithm and a multiple-antenna time-division multiplexing location system. A graphical user interface (GUI) was developed for collecting temperature and location data for the data fusion by using RFID protocols. With a puppy as test object, temperature detection and localization experiments were carried out. The measured results show that the applied method, when using a mercury thermometer for comparison in terms of measuring the temperature of the dog, has a good consistency, with an average temperature error of 0.283 °C. When using the associated program over the area of 12.25 m2, the average location error is of 0.461 m, which verifies the feasibility of the sensor-carrier location by using the proposed program.

  12. Comparison of body-powered voluntary opening and voluntary closing prehensor for activities of daily life.

    Science.gov (United States)

    Berning, Kelsey; Cohick, Sarah; Johnson, Reva; Miller, Laura Ann; Sensinger, Jonathon W

    2014-01-01

    Persons with an upper-limb amputation who use a body-powered prosthesis typically control the prehensor through contralateral shoulder movement, which is transmitted through a Bowden cable. Increased cable tension either opens or closes the prehensor; when tension is released, some passive element, such as a spring, returns the prehensor to the default state (closed or open). In this study, we used the Southampton Hand Assessment Procedure to examine functional differences between these two types of prehensors in 29 nondisabled subjects (who used a body-powered bypass prosthesis) and 2 persons with unilateral transradial amputations (who used a conventional body-powered device). We also administered a survey to determine whether subjects preferred one prehensor or the other for specific tasks, with a long-term goal of assessing whether a prehensor that could switch between both modes would be advantageous. We found that using the voluntary closing prehensor was 1.3 s faster (p = 0.02) than using the voluntary opening prehensor, across tasks, and that there was consensus among subjects on which types of tasks they preferred to do with each prehensor type. Twenty-five subjects wanted a device that could switch between the two modes in order to perform particular tasks.

  13. Toddlers actively reorganize their whole body coordination to maintain walking stability while carrying an object.

    Science.gov (United States)

    Hsu, Wen-Hao; Miranda, Daniel L; Chistolini, Trevor L; Goldfield, Eugene C

    2016-10-01

    Balanced walking involves freely swinging the limbs like pendula. However, children immediately begin to carry objects as soon as they can walk. One possibility for this early skill development is that whole body coordination during walking may be re-organized into loosely coupled collections of body parts, allowing children to use their arms to perform one function, while the legs perform another. Therefore, this study examines: 1) how carrying an object affects the coordination of the arms and legs during walking, and 2) if carrying an object influences stride length and width. Ten healthy toddlers with 3-12 months of walking experience were recruited to walk barefoot while carrying or not carrying a small toy. Stride length, width, speed, and continuous relative phase (CRP) of the hips and of the shoulders were compared between carrying conditions. While both arms and legs demonstrated destabilization and stabilization throughout the gait cycle, the arms showed a reduction in intra-subject coordination variability in response to carrying an object. Carrying an object may modify the function of the arms from swinging for balance to maintaining hold of an object. The observed period-dependent changes of the inter-limb coordination of the hips and of the shoulders also support this interpretation. Overall, these findings support the view that whole-body coordination patterns may become partitioned in particular ways as a function of task requirements.

  14. Comparison of body-powered voluntary opening and voluntary closing prehensor for activities of daily life

    Directory of Open Access Journals (Sweden)

    Kelsey Berning

    2014-05-01

    Full Text Available Persons with an upper-limb amputation who use a body-powered prosthesis typically control the prehensor through contralateral shoulder movement, which is transmitted through a Bowden cable. Increased cable tension either opens or closes the prehensor; when tension is released, some passive element, such as a spring, returns the prehensor to the default state (closed or open. In this study, we used the Southampton Hand Assessment Procedure to examine functional differences between these two types of prehensors in 29 nondisabled subjects (who used a body-powered bypass prosthesis and 2 persons with unilateral transradial amputations (who used a conventional body-powered device. We also administered a survey to determine whether subjects preferred one prehensor or the other for specific tasks, with a long-term goal of assessing whether a prehensor that could switch between both modes would be advantageous. We found that using the voluntary closing prehensor was 1.3 s faster (p = 0.02 than using the voluntary opening prehensor, across tasks, and that there was consensus among subjects on which types of tasks they preferred to do with each prehensor type. Twenty-five subjects wanted a device that could switch between the two modes in order to perform particular tasks.

  15. Physical Workload Analysis Among Small Industry Activities Using Postural Data.

    Science.gov (United States)

    Rabiul Ahasan, M; Väyrynen, Seppo; Kirvesoja, Heli

    1996-01-01

    Small industry workers are often involved in manual handling operations that require awkward body postures, therefore, musculoskeletal disorders and occupational injuries are a major problem. In this study, various types of tasks were recorded with a video camera to chart and analyze different postures by computerized OWAS (Ovako Working Posture Analysing System). Collected data showed that poor postures were adopted not only for lifting or hammering operation but also for other tasks; mostly with bent and twisted back. The main aim was to determine the physical workload by identifying harmful postures and to develop recommendations for improving the existing situation. Forty-eight male workers from eight different units (M age = 37 years) participated. The performed activities were then divided into 26 subtasks. Altogether, 1,534 postures were selected for analysis and then classified into different OAC (OWAS Action Categories). From all observations, unhealthy postures, for which corrective measures had to be considered immediately (i.e., 10.6% classified as OAC III, and 3.3% as OAC IV), were found. The applied method was useful in determining the physical workload by locating potential activities due to harmful postures, providing a detailed description with analysis, and suggesting successful means to reduce postural load.

  16. Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations.

    Science.gov (United States)

    Khundakar, Ahmad A; Hanson, Peter S; Erskine, Daniel; Lax, Nichola Z; Roscamp, Joseph; Karyka, Evangelia; Tsefou, Eliona; Singh, Preeti; Cockell, Simon J; Gribben, Andrew; Ramsay, Lynne; Blain, Peter G; Mosimann, Urs P; Lett, Deborah J; Elstner, Matthias; Turnbull, Douglass M; Xiang, Charles C; Brownstein, Michael J; O'Brien, John T; Taylor, John-Paul; Attems, Johannes; Thomas, Alan J; McKeith, Ian G; Morris, Christopher M

    2016-06-30

    Dementia with Lewy bodies (DLB) patients frequently experience well formed recurrent complex visual hallucinations (RCVH). This is associated with reduced blood flow or hypometabolism on imaging of the primary visual cortex. To understand these associations in DLB we used pathological and biochemical analysis of the primary visual cortex to identify changes that could underpin RCVH. Alpha-synuclein or neurofibrillary tangle pathology in primary visual cortex was essentially absent. Neurone density or volume within the primary visual cortex in DLB was also unchanged using unbiased stereology. Microarray analysis, however, demonstrated changes in neuropeptide gene expression and other markers, indicating altered GABAergic neuronal function. Calcium binding protein and GAD65/67 immunohistochemistry showed preserved interneurone populations indicating possible interneurone dysfunction. This was demonstrated by loss of post synaptic GABA receptor markers including gephyrin, GABARAP, and Kif5A, indicating reduced GABAergic synaptic activity. Glutamatergic neuronal signalling was also altered with vesicular glutamate transporter protein and PSD-95 expression being reduced. Changes to the primary visual cortex in DLB indicate that reduced GABAergic transmission may contribute to RCVH in DLB and treatment using targeted GABAergic modulation or similar approaches using glutamatergic modification may be beneficial.

  17. A multi-tissue type genome-scale metabolic network for analysis of whole-body systems physiology

    Directory of Open Access Journals (Sweden)

    Feist Adam M

    2011-10-01

    Full Text Available Abstract Background Genome-scale metabolic reconstructions provide a biologically meaningful mechanistic basis for the genotype-phenotype relationship. The global human metabolic network, termed Recon 1, has recently been reconstructed allowing the systems analysis of human metabolic physiology and pathology. Utilizing high-throughput data, Recon 1 has recently been tailored to different cells and tissues, including the liver, kidney, brain, and alveolar macrophage. These models have shown utility in the study of systems medicine. However, no integrated analysis between human tissues has been done. Results To describe tissue-specific functions, Recon 1 was tailored to describe metabolism in three human cells: adipocytes, hepatocytes, and myocytes. These cell-specific networks were manually curated and validated based on known cellular metabolic functions. To study intercellular interactions, a novel multi-tissue type modeling approach was developed to integrate the metabolic functions for the three cell types, and subsequently used to simulate known integrated metabolic cycles. In addition, the multi-tissue model was used to study diabetes: a pathology with systemic properties. High-throughput data was integrated with the network to determine differential metabolic activity between obese and type II obese gastric bypass patients in a whole-body context. Conclusion The multi-tissue type modeling approach presented provides a platform to study integrated metabolic states. As more cell and tissue-specific models are released, it is critical to develop a framework in which to study their interdependencies.

  18. Bilateral flight muscle activity predicts wing kinematics and 3-dimensional body orientation of locusts responding to looming objects.

    Science.gov (United States)

    McMillan, Glyn A; Loessin, Vicky; Gray, John R

    2013-09-01

    We placed locusts in a wind tunnel using a loose tether design that allowed for motion in all three rotational degrees of freedom during presentation of a computer-generated looming disc. High-speed video allowed us to extract wing kinematics, abdomen position and 3-dimensional body orientation. Concurrent electromyographic (EMG) recordings monitored bilateral activity from the first basalar depressor muscles (m97) of the forewings, which are implicated in flight steering. Behavioural responses to a looming disc included cessation of flight (wings folded over the body), glides and active steering during sustained flight in addition to a decrease and increase in wingbeat frequency prior to and during, respectively, an evasive turn. Active steering involved shifts in bilateral m97 timing, wing asymmetries and whole-body rotations in the yaw (ψ), pitch (χ) and roll (η) planes. Changes in abdomen position and hindwing asymmetries occurred after turns were initiated. Forewing asymmetry and changes in η were most highly correlated with m97 spike latency. Correlations also increased as the disc approached, peaking prior to collision. On the inside of a turn, m97 spikes occurred earlier relative to forewing stroke reversal and bilateral timing corresponded to forewing asymmetry as well as changes in whole-body rotation. Double spikes in each m97 occurred most frequently at or immediately prior to the time the locusts turned, suggesting a behavioural significance. These data provide information on mechanisms underlying 3-dimensional flight manoeuvres and will be used to drive a closed loop flight simulator to study responses of motion-sensitive visual neurons during production of realistic behaviours.

  19. Body mass index and risk of pneumonia: a systematic review and meta-analysis.

    Science.gov (United States)

    Phung, D T; Wang, Z; Rutherford, S; Huang, C; Chu, C

    2013-10-01

    The aims of our meta-analysis were to examine the pattern and gender's influence on body mass index (BMI) - pneumonia relationship. Published studies were searched from PubMed, Web of Science, Cochrane Library databases using keywords of pneumonia, BMI and epidemiologic studies. Random-effects analysis was applied to estimate pooled effect sizes from individual studies. The Cochrane Q-test and index of heterogeneity (I(2) ) were used to evaluate heterogeneity, and Egger's test was used to evaluate publication bias. Random-effects meta-regression was applied to examine the pattern and gender's influence on BMI-pneumonia relationship. A total of 1,531 studies were initially identified, and 25 studies finally were included. The pooled relative risk (RR) and meta-regression model revealed a J-shaped relationship between BMI and risk of community-acquired pneumonia (underweight, RR 1.8, 95% confidence interval [CI], 1.4-2.2, P pneumonia (underweight, RR 1.9, 95% CI, 1.2-3, P pneumonia was found across the BMI groups. Gender difference did not make significant contribution in modifying BMI-pneumonia risk relationship.

  20. Response of Autonomic Nervous System to Body Positions: Fourier and Wavelet Analysis

    CERN Document Server

    Xu, A; Federici, A; Stramaglia, S; Simone, F; Zenzola, A; Santostasi, R; Xu, Aiguo

    2003-01-01

    Two mathematical methods, the Fourier and wavelet transforms, were used to study the short term cardiovascular control system. Time series, picked from electrocardiogram and arterial blood pressure lasting 6 minutes, were analyzed in supine position (SUP), during the first (HD1), and the second half (HD2) of $90^{\\circ}$ head down tilt and during recovery (REC). The wavelet transform was performed using the Haar function of period $T=2^j$ ($% j=1$,2,$... $,6) to obtain wavelet coefficients. Power spectra components were analyzed within three bands, VLF (0.003-0.04), LF (0.04-0.15) and HF (0.15-0.4) with the frquency unit cycle/interval. Wavelet transform demonstrated a higher discrimination among all analyzed periods than the Fourier transform. For the Fourier analysis, the LF of R-R intervals and VLF of systolic blood pressure show more evident difference for different body positions. For the wavelet analysis, the systolic blood pressures show much more evident difference than the R-R intervals. This study s...

  1. Treatment of traumatised refugees with basic body awareness therapy versus mixed physical activity as add-on treatment

    DEFF Research Database (Denmark)

    Nordbrandt, Maja Sticker; Carlsson, Jessica; Lindberg, Laura Glahder

    2015-01-01

    . In clinical studies, physical activity has shown a positive effect on psychiatric illnesses such as depression and anxiety and for patients with chronic pain. However, scientific knowledge about physical activity as part of the treatment for traumatised refugees is very limited and no guidelines exist......-based Cognitive Behavioural Therapy. The first group only receives treatment as usual while the second and the third groups receive either Basic-Body Awareness Therapy or mixed physical activity as add-on treatments. Each physical activity is provided for an individual 1-hour consultation per week......, for the duration of 20 weeks. The study is being conducted at the Competence Centre for Transcultural Psychiatry, Mental Health Centre Ballerup in the Capital Region of Denmark. The primary endpoint of the study is symptoms of Post Traumatic Stress Disorder; the secondary endpoints are depression and anxiety...

  2. A historical discourse analysis of the cancerous and non-cancerous body in secondary biology textbooks

    Science.gov (United States)

    Bowers, Neil Thomas

    This dissertation applies the archeological concepts developed by Michel Foucault to a study of thirteen biology textbooks (1993-2004) in order to develop an understanding of 'purchased truths' concerning cancer. This study focuses on the construction of the health/illness dialogue concerning cancer within the textbooks and not the meaning that the individual makes from reading the text; as such this study concerns itself with social truths rather than the search for an individual awareness of names, dates, or places. This study investigates the practices that allow the creation of dialogues that are inserted into a biology textbook and looks at how discursive formations create the 'truth regime' from which the biology textbook is said to speak. Using the Foucaultian themes of 'event', 'emergence', 'enunciation', and 'exteriority' a new reading of topics concerning cancer emerge from biology textbooks. Cancer is a disease that will impact the lives of countless individuals but coverage devoted to the pathology of cancer in secondary biology textbooks is very limited and no study textbook devoted a whole chapter to the discussion of cancer. There is an identified reduction in the number of pages and depth of coverage devoted to cancer in the newer biology texts compared to the older texts. Humans are pictured more than plants or animals in presentations concerning cancer with emphasis being placed on the digitalization of human cells via the scanning electron microscope. When the whole body is presented it is seldom located within the technology of disease diagnosis and treatment but rather is posed for specific social control. Just as each digitized picture of the cancerous cell in the texts is used to create a story so too are the pictures of the whole body in action. Possible story lines offered by the publishing houses concerning the reaction of the body to cancer are shown to intermingle with risk factor analysis to project a sense of Foucaultian

  3. Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster

    Directory of Open Access Journals (Sweden)

    Jordan Katherine W

    2010-05-01

    Full Text Available Abstract Background Obesity and phenotypic traits associated with this condition exhibit significant heritability in natural populations of most organisms. While a number of genes and genetic pathways have been implicated to play a role in obesity associated traits, the genetic architecture that underlies the natural variation in these traits is largely unknown. Here, we used 40 wild-derived inbred lines of Drosophila melanogaster to quantify genetic variation in body weight, the content of three major metabolites (glycogen, triacylglycerol, and glycerol associated with obesity, and metabolic rate in young flies. We chose these lines because they were previously screened for variation in whole-genome transcript abundance and in several adult life-history traits, including longevity, resistance to starvation stress, chill-coma recovery, mating behavior, and competitive fitness. This enabled us not only to identify candidate genes and transcriptional networks that might explain variation for energy metabolism traits, but also to investigate the genetic interrelationships among energy metabolism, behavioral, and life-history traits that have evolved in natural populations. Results We found significant genetically based variation in all traits. Using a genome-wide association screen for single feature polymorphisms and quantitative trait transcripts, we identified 337, 211, 237, 553, and 152 novel candidate genes associated with body weight, glycogen content, triacylglycerol storage, glycerol levels, and metabolic rate, respectively. Weighted gene co-expression analyses grouped transcripts associated with each trait in significant modules of co-expressed genes and we interpreted these modules in terms of their gene enrichment based on Gene Ontology analysis. Comparison of gene co-expression modules for traits in this study with previously determined modules for life-history traits identified significant modular pleiotropy between glycogen content

  4. Standardization of a Volumetric Displacement Measurement for Two-Body Abrasion Scratch Test Data Analysis

    Science.gov (United States)

    Street, K. W. Jr.; Kobrick, R. L.; Klaus, D. M.

    2011-01-01

    A limitation has been identified in the existing test standards used for making controlled, two-body abrasion scratch measurements based solely on the width of the resultant score on the surface of the material. A new, more robust method is proposed for analyzing a surface scratch that takes into account the full three-dimensional profile of the displaced material. To accomplish this, a set of four volume- displacement metrics was systematically defined by normalizing the overall surface profile to denote statistically the area of relevance, termed the Zone of Interaction. From this baseline, depth of the trough and height of the plowed material are factored into the overall deformation assessment. Proof-of-concept data were collected and analyzed to demonstrate the performance of this proposed methodology. This technique takes advantage of advanced imaging capabilities that allow resolution of the scratched surface to be quantified in greater detail than was previously achievable. When reviewing existing data analysis techniques for conducting two-body abrasive scratch tests, it was found that the ASTM International Standard G 171 specified a generic metric based only on visually determined scratch width as a way to compare abraded materials. A limitation to this method was identified in that the scratch width is based on optical surface measurements, manually defined by approximating the boundaries, but does not consider the three-dimensional volume of material that was displaced. With large, potentially irregular deformations occurring on softer materials, it becomes unclear where to systematically determine the scratch width. Specifically, surface scratches on different samples may look the same from a top view, resulting in an identical scratch width measurement, but may vary in actual penetration depth and/or plowing deformation. Therefore, two different scratch profiles would be measured as having identical abrasion properties, although they differ

  5. Influence of perceived sport competence and body attractiveness on physical activity and other healthy lifestyle habits in adolescents.

    Science.gov (United States)

    Moreno-Murcia, Juan Antonio; Hellín, Pedro; González-Cutre, David; Martínez-Galindo, Celestina

    2011-05-01

    The purpose of this study was to test an explanatory model of the relationships between physical self-concept and some healthy habits. A sample of 472 adolescents aged 16 to 20 answered different questionnaires assessing physical self-concept, physical activity, intention to be physically active and consumption of alcohol and tobacco. The results of the structural equation model showed that perceived sport competence positively correlated with current physical activity. Body attractiveness positively correlated with physical activity in boys and negatively in girls. Current physical activity positively correlated with the intention to be physically active in the future and negatively with the consumption of alcohol and tobacco. Nevertheless, this last relationship was only significant in boys. The results are discussed in connection with the promotion of healthy lifestyle guidelines among adolescents. This model shows the importance of physical self-concept for engaging in physical activity in adolescence. It also suggests that physical activity is associated with the intention to continue being physically active and with healthy lifestyle habits.

  6. Evaluation of the minimum detectable activity of whole-body and thyroid counters of the in vivo monitoring laboratory of IPEN/CNEN-SP

    Energy Technology Data Exchange (ETDEWEB)

    Santos, L.R.; Xavier, M.; Kakoi, A.A.Y.; Silva Junior, I.A.; Cardoso, J.C.S., E-mail: dossantos.lucasrodrigues@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2012-07-01

    Quality assurance in whole-body measurement includes quality control with procedure descriptions, detector calibrations, instrument control and evaluation internally or by outside persons. The In Vivo Monitoring Laboratory of IPEN/CNEN-SP (LMIV) provides a direct way activity measure of internally incorporated radionuclides in occupationally exposed workers. LMIV has two NaI(Tl) of 8x4'' and 2x2'' to perform the monitoring of whole-body and thyroid, respectively. The acquisition and analysis software was Genie2000 3.2, Canberra. The system calibration was carried out with Eu-152, Am-241 and Co-60 sources positioned within Alderson Research Labs. anthropomorphic phantom. Minimum detectable activity (MDA) and critical level (Lc) values for nuclides of interest were determined, since these values are an indication of the sensitivity of the detection system. The background counts were obtained from the first monitoring of some workers, blank measurements. The concepts adopted in the HPS N13.30 Standard and proposed in ISO documents for standardization were used for activity measurements. (author)

  7. EFFECTS OF SPORTS AND SCIENCE HIGH SCHOOL STUDENTS’ SPORTS ACTIVITY LEVELS ON BODY COMPOSITION AND BONE MINERAL DENSITY

    Directory of Open Access Journals (Sweden)

    Hasan Aykut AYSAN

    2015-08-01

    Full Text Available Purpose: In this study, effects of sports and science high school students’ sports activity levels on their body composition and bone development level were investigated. Material and Method: A total of 59 participants were voluntarily included in the study in which 29 people were the experimental group from Elazıg Kaya Karakaya Sports High School with a mean age of 17.10±1.25 (years and 30 people were the control group fr om Diyarbakır RekabetKurumu High School with a mean age of 17.70±1.67 (years . Sports activity of Sports High school students was found to include (in the first two years 384 hours, a total of 1088 hours in four years and sports activity of science high s chool students was found to include ( in the first 2 years 94, a total of 158 hours in four years. Those who had any disease that could have an effect on their bone mineral density and body compositions were not included in the study. Height and weight w ere measure with standardSecaStadiometre . Body Mass Index (BMI, Basal Metabolic Rate (BMR, Body Fat Percentage (BFP, Body Fat Mass (BFM, Fat - Free Body Mass (FBM, Total Body Water (TBW , which constitute body composition and are accepted as sub parame ters, were measured with Bioelectrical Impedance Analyser (BIA - Tanita BC 418 . Bone densitometry device (DEXA; Hologic Discovery 4500 QDR was used in the measurements of bone mineral density. SPSS 16.0 was used in the process of the raw data obtained and T - Test was applied for independent samples. Findings : HEIGHT, WEIGHT, BMI, BMR, %BFP, BFM, FBM, TBW measured mean values of the E xperimental group are 171.62±7.078 (cm, 58.88±8.679 (kg, 19.89±1.745 (kg/m², 3435.6 ± 2660.55 (kcal, 13.64±2.446 (%,8.100± 2.150 (kg, 50.81±7.165 (kg respectively. HEIGHT, WEIGHT, BMI, BMR, %BFP, BFM, FBM, TBW measured mean values of the Control group are 170.21±8.514 (cm, 59.77±9.749 (kg, 19.63±1.439 (kg/m², 2362.85 ± 2010.71 (kcal, 13.83±2.556 (%, 8.048±1.708 (kg, 5 0

  8. Associations of prepartum body condition score with occurrence of clinical endometritis and resumption of postpartum ovarian activity in dairy cattle.

    Science.gov (United States)

    Kadivar, Ali; Ahmadi, Mohammad Rahim; Vatankhah, Mahmood

    2014-01-01

    This study was performed to investigate the effect of periparturient body condition score on the occurrence of clinical endometritis and postpartum resumption of ovarian activity in dairy cows. Eighty-seven lactating Holstein cows, fed with a total mixed ration diet, were included into the study. Body condition scoring (using a 5-point scale with quarter-point divisions) was performed by the same investigator using the visual technique every 2 weeks, from 2 weeks before until 6 weeks after calving. Palpation of the reproductive tract and ultrasonographic assessment of ovaries for detection of corpus luteum using a rectal linear probe was also performed at 2, 4, and 6 weeks after calving. Cows with clinical endometritis had significantly lower body condition score (BCS) than normal cows at all weeks pre- and postcalving, and cows that did not ovulate until 45 days after calving had a significantly lower BCS pre- and postpartum. Cows that did not ovulate until 45 days after calving also lost more BCS from 2 weeks before to 4 weeks after calving. Besides, first ovulation after calving take occurred later in cows with clinical endometritis compared to normal cows (P BCS is a risk factor for postpartum endometritis and delayed cyclicity in dairy cows. BCS loss from dry-off to early lactation and occurrence of clinical endometritis can significantly affect postpartum ovarian activity.

  9. Voxelwise meta-analysis of gray matter abnormalities in dementia with Lewy bodies

    Energy Technology Data Exchange (ETDEWEB)

    Zhong, JianGuo; Pan, PingLei [Department of Neurology, Affiliated Yancheng Hospital of Southeast University, Yancheng (China); Dai, ZhenYu [Department of Radiology, Affiliated Yancheng Hospital of Southeast University, Yancheng (China); Shi, HaiCun, E-mail: yc3yhcshi@gmail.com [Department of Neurology, Affiliated Yancheng Hospital of Southeast University, Yancheng (China)

    2014-10-15

    Highlights: • We first report the meta-analyses of GM anomalies by VBM studies in DLB. • Lateral temporal/insular and lenticular nucleus/insular cortex atrophy were detected. • A characteristic pattern of GM changes underpinned DLB. - Abstract: Background: Increasing neuroimaging studies have revealed brain gray matter (GM) atrophy by voxel-based morphometry (VBM) studies in patients with dementia with Lewy bodies (DLB) relative to healthy controls. However, the spatial localization of GM abnormalities reported in the existing studies is heterogeneous. Here, we aimed to investigate concurrence across VBM studies to help clarify the structural abnormalities underpinning this condition. Methods: A systematic search for VBM studies of DLB patients and healthy controls published in PubMed database from January 2000 to March 2014 was conducted. A quantitative meta-analysis of whole-brain VBM studies in DLB patients and healthy controls was performed by means of Anisotropic Effect Size version of Signed Differential Mapping (AES-SDM) software package. Results: Seven studies comprising 218 DLB patients and 219 healthy controls were included in the present study. Compared to healthy subjects, the patients group showed consistent decreased GM in right lateral temporal/insular cortex and left lenticular nucleus/insular cortex. The results remained largely unchanged in the following jackknife sensitivity analyses. Meta-regression analysis indicated an increased probability of finding brain atrophy in left superior temporal gyrus in patients with lower MMSE scores. Conclusions: The present meta-analysis quantitatively demonstrates a characteristic pattern of GM alternations that contributed to the understanding of pathophysiology underlying DLB. Future studies will benefit from employing meta-analytical comparisons to other dementia subtypes with solid evidence to extend these findings.

  10. Proton induced X-ray emission (PIXE) analysis of sources of porcelain body of Ru Guan and Jun Guan porcelains

    Institute of Scientific and Technical Information of China (English)

    LI Guoxia; ZHAO Wenjun; CHENG Huansheng; ZHAO Weijuan; LI Rongwu; SUN Hongwei; GUO Min; WANG Yanfang; LIU Hui; ZHAO Qingyun; SUN Xinmin

    2006-01-01

    34 samples of Ru Guan porcelain body and 50 samples of Jun Guan porcelain body (both kinds being in different body colors) were selected with the purpose of finding out the source of raw materials and their classification relationship so as to search for ways of non-destructive discrimination. Proton induced X-ray emission (PIXE) has been applied to these samples to determine their chemical elements. The data of seven major chemical elements collected from these samples were further studied through fuzzy cluster analysis. Results indicate that the origin of raw materials of Jun Guan porcelain body samples is comparatively more concentrated in certain places, while that of Ru Guan porcelain body samples is scattered about. The places of origin of raw materials of the majority of Ru Guan and Jun Guan porcelain body samples have something in common, but some differences still exist. It might be an important way for non-destructive discrimination among Ru Guan and Jun Guan porcelains by combining PIXE with fuzzy cluster analysis.

  11. Cathinone increases body temperature, enhances locomotor activity, and induces striatal c-fos expression in the Siberian hamster.

    Science.gov (United States)

    Jones, S; Fileccia, E L; Murphy, M; Fowler, M J; King, M V; Shortall, S E; Wigmore, P M; Green, A R; Fone, K C F; Ebling, F J P

    2014-01-24

    Cathinone is a β-keto alkaloid that is the major active constituent of khat, the leaf of the Catha edulis plant that is chewed recreationally in East Africa and the Middle East. Related compounds, such as methcathinone and mephedrone have been increasing in popularity as recreational drugs, resulting in the recent proposal to classify khat as a Class C drug in the UK. There is still limited knowledge of the pharmacological effects of cathinone. This study examined the acute effects of cathinone on core body temperature, locomotor and other behaviors, and neuronal activity in Siberian hamsters. Adult male hamsters, previously implanted with radio telemetry devices, were treated with cathinone (2 or 5mg/kg i.p.), the behavioral profile scored and core body temperature and locomotor activity recorded by radio telemetry. At the end of the study, hamsters received vehicle or cathinone (5mg/kg) and neuronal activation in the brain was determined using immunohistochemical evaluation of c-fos expression. Cathinone dose-dependently induced significant (phamster.

  12. Critical body residues linked to octanol-water partitioning, organism composition, and LC50 QSARs: meta-analysis and model.

    Science.gov (United States)

    Hendriks, A Jan; Traas, Theo P; Huijbregts, Mark A J

    2005-05-01

    To protect thousands of species from thousands of chemicals released in the environment, various risk assessment tools have been developed. Here, we link quantitative structure-activity relationships (QSARs) for response concentrations in water (LC50) to critical concentrations in organisms (C50) by a model for accumulation in lipid or non-lipid phases versus water Kpw. The model indicates that affinity for neutral body components such as storage fat yields steep Kpw-Kow relationships, whereas slopes for accumulation in polar phases such as proteins are gentle. This pattern is confirmed by LC50 QSARs for different modes of action, such as neutral versus polar narcotics and organochlorine versus organophosphor insecticides. LC50 QSARs were all between 0.00002 and 0.2Kow(-1). After calibrating the model with the intercepts and, for the first time also, with the slopes of the LC50 QSARs, critical concentrations in organisms C50 are calculated and compared to an independent validation data set. About 60% of the variability in lethal body burdens C50 is explained by the model. Explanations for differences between estimated and measured levels for 11 modes of action are discussed. In particular, relationships between the critical concentrations in organisms C50 and chemical (Kow) or species (lipid content) characteristics are specified and tested. The analysis combines different models proposed before and provides a substantial extension of the data set in comparison to previous work. Moreover, the concept is applied to species (e.g., plants, lean animals) and substances (e.g., specific modes of action) that were scarcely studied quantitatively so far.

  13. A self-determination theory approach to adults' healthy body weight motivation: A longitudinal study focussing on food choices and recreational physical activity.

    Science.gov (United States)

    Hartmann, Christina; Dohle, Simone; Siegrist, Michael

    2015-01-01

    This study focuses on body weight motivation based on self-determination theory. The impact of body weight motivation on longitudinal changes in food choices, recreational physical activity and body mass index was explored. A sample of adults (N = 2917, 47% men), randomly selected from the telephone book, completed a questionnaire in two consecutive years (2012, 2013), self-reporting food choices, recreational physical activity and body weight motivation. Types of body weight motivation at T1 (autonomous regulation, introjected regulation, and external regulation) were tested with regard to their predictive potential for changes in food choices, recreational physical activity and body mass index (BMI). Autonomous motivation predicted improvements in food choices and long-term adherence to vigorous recreational physical activity in both genders. Introjected motivation predicted long-term adherence to vigorous recreational physical activity only in women. External motivation predicted negative changes in food choices; however, the type of body weight motivation had no impact on BMI in overweight adults in the long term. Autonomous goal-setting regarding body weight seems to be substantial for healthy food choices and adherence to recreational physical activity.

  14. Body electrical loss analysis (BELA in the assessment of visceral fat: a demonstration

    Directory of Open Access Journals (Sweden)

    Blomqvist Kim H

    2011-11-01

    Full Text Available Abstract Background Body electrical loss analysis (BELA is a new non-invasive way to assess visceral fat depot size through the use of electromagnetism. BELA has worked well in phantom measurements, but the technology is not yet fully validated. Methods Ten volunteers (5 men and 5 women, age: 22-60 y, BMI: 21-30 kg/m2, waist circumference: 73-108 cm were measured with the BELA instrument and with cross-sectional magnetic resonance imaging (MRI at the navel level, navel +5 cm and navel -5 cm. The BELA signal was compared with visceral and subcutaneous fat areas calculated from the MR images. Results The BELA signal did not correlate with subcutaneous fat area at any level, but correlated significantly with visceral fat area at the navel level and navel +5 cm. The correlation was best at level of navel +5 cm (R2 = 0.74, P 2, LOOCV = 40.1 cm2, where SEE is the standard error of the estimate and LOOCV is the root mean squared error of leave-one-out style cross-validation. The average estimate of repeatability of the BELA signal observed through the study was ±9.6 %. One of the volunteers had an exceptionally large amount of visceral fat, which was underestimated by BELA. Conclusions The correlation of the BELA signal with the visceral but not with the subcutaneous fat area as measured by MRI is promising. The lack of correlation with the subcutaneous fat suggests that subcutaneous fat has a minor influence to the BELA signal. Further research will show if it is possible to develop a reliable low-cost method for the assessment of visceral fat either using BELA only or combining it, for example, with bioelectrical impedance measurement. The combination of these measurements may help assessing visceral fat in a large scale of body composition. Before large-scale clinical testing and ROC analysis, the initial BELA instrumentation requires improvements. The accuracy of the present equipment is not sufficient for such new technology.

  15. Human Body Exergy Balance: Numerical Analysis of an Indoor Thermal Environment of a Passive Wooden Room in Summer

    Directory of Open Access Journals (Sweden)

    Koichi Isawa

    2015-09-01

    Full Text Available To obtain a basic understanding of the resultant changes in the human body exergy balance (input, consumption, storage, and output accompanying outdoor air temperature fluctuations, a “human body system and a built environmental system” coupled with numerical analysis was conducted. The built environmental system assumed a wooden room equipped with passive cooling strategies, such as thermal insulation and solar shading devices. It was found that in the daytime, the cool radiation exergy emitted by surrounding surfaces, such as walls increased the rate of human body exergy consumption, whereas the warm radiant exergy emitted by the surrounding surfaces at night decreased the rate of human body exergy consumption. The results suggested that the rates and proportions of the different components in the exergy balance equation (exergy input, consumption, storage, and output vary according to the outdoor temperature and humidity conditions.

  16. Vaspin association with insulin resistance is related to physical activity and body fat in Brazilian adolescents: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Daniela Pala

    Full Text Available Background: Vaspin is a newly-identified adipocytokine associated with insulin resistance (IR. Objective: The aim of this study was to investigate the correlation between plasma vaspin concentrations and IR and determine whether this association is affected by body composition, physical activity and pubertal stage in adolescents. Methods: Were studied 484 Brazilian adolescents aged 10-14 years whose anthropometric, clinical, biochemical, and lifestyle measurements were analized. We evaluated the correlation between vaspin and risk factors for IR in adolescents with normal and high body fat percentage (%BF and did a logistic regression to calculate the odds ratio for IR according to vaspin quartiles sex specific for the sample. Results: Vaspin was positively correlated with IR in adolescents with high %BF (r = 0.23, p = 0.003. The logistic regression analysis adjusted for sex, age, BMI, and pubertal stage showed that adolescents in the 2nd (OR = 0.43, 95% CI = 0.23-0.80, p = 0.008 and 3rd (OR = 0.46, 95% CI = 0.25-0.85, p = 0.014 quartile of vaspin concentration had a lower risk for IR. When the model was adjusted for %BF and physical activity, the association remained statically significant only for adolescents in the 2nd quartile. Conclusion: Vaspin was correlated positively with risk factors associated with insulin metabolism in adolescents with high %BF. Vaspin was associated with a reduced risk of IR independently of BMI and pubertal stage and the association was influenced by body fat and physical activity in these adolescents.

  17. Evaluation of body composition in COPD patients using multifrequency bioelectrical impedance analysis

    Directory of Open Access Journals (Sweden)

    de Blasio F

    2016-09-01

    Full Text Available Francesca de Blasio,1 Francesco de Blasio,2,3 Giulia Miracco Berlingieri,2 Andrea Bianco,3,4 Marta La Greca,1 Frits M E Franssen,5 Luca Scalfi1 1Department of Public Health, Medical School, “Federico II” University of Naples, 2Respiratory Medicine and Pulmonary Rehabilitation Section, Clinic Center, Private Hospital, Naples, 3Department of Medicine and Health Sciences “V Tiberio”, University of Molise, Campobasso, 4Department of Cardio-Thoracic and Respiratory Sciences, Second University of Naples, Naples, Italy; 5Department of Research and Education, CIRO, Horn, the NetherlandsBackground: Multifrequency bioelectrical impedance analysis (MF-BIA is a technique that measures body impedance (Z at different frequencies (5, 10, 50, 100, and 250 kHz. Body composition may be estimated using empirical equations, which include BIA variables or, alternatively, raw BIA data may provide direct information on water distribution and muscle quality.Objectives: To compare raw MF-BIA data between COPD patients and controls and to study their relationship with respiratory and functional parameters in COPD patients.Methods: MF-BIA was performed (Human Im-Touch analyzer in 212 COPD patients and 115 age- and BMI-matched controls. Fat-free mass (FFM and fat mass were estimated from BIA data, and low- to high-frequency (5 kHz/250 kHz impedance ratio was calculated. Physical fitness, lung function and respiratory muscle strength were also assessed in COPD patients.Results: After adjusting for age, weight, and body mass index, FFM and the 5/250 impedance ratio were lower in COPD patients (P<0.001 and were negatively affected by disease severity. In both male and female patients, the 5/250 impedance ratio was significantly correlated mainly with age (r=−0.316 and r=−0.346, respectively. Patients with a 5/250 impedance ratio below median value had lower handgrip strength (P<0.001, 6-minute walk distance (P<0.005, respiratory muscle strength (P<0.005, forced

  18. Activity-dependent gene expression in honey bee mushroom bodies in response to orientation flight.

    Science.gov (United States)

    Lutz, Claudia C; Robinson, Gene E

    2013-06-01

    The natural history of adult worker honey bees (Apis mellifera) provides an opportunity to study the molecular basis of learning in an ecological context. Foragers must learn to navigate between the hive and floral locations that may be up to miles away. Young pre-foragers prepare for this task by performing orientation flights near the hive, during which they begin to learn navigational cues such as the appearance of the hive, the position of landmarks, and the movement of the sun. Despite well-described spatial learning and navigation behavior, there is currently limited information on the neural basis of insect spatial learning. We found that Egr, an insect homolog of Egr-1, is rapidly and transiently upregulated in the mushroom bodies in response to orientation. This result is the first example of an Egr-1 homolog acting as a learning-related immediate-early gene in an insect and also demonstrates that honey bee orientation uses a molecular mechanism that is known to be involved in many other forms of learning. This transcriptional response occurred both in naïve bees and in foragers induced to re-orient. Further experiments suggest that visual environmental novelty, rather than exercise or memorization of specific visual cues, acts as the stimulus for Egr upregulation. Our results implicate the mushroom bodies in spatial learning and emphasize the deep conservation of Egr-related pathways in experience-dependent plasticity.

  19. DANCE ACTIVITY AS BODY LANGUAGE AND THE DEVELOPMENT OF MEMORY IN CHILDREN WITH DOWN SYNDROME.

    Directory of Open Access Journals (Sweden)

    Ariana Aparecida Nascimento dos Santos

    2013-07-01

    Full Text Available Considering the difficulties and limitations that Down’s Syndrome individuals have and taking into account historic-cultural theory’s contributions to understand the voluntary memory as fundamental to human development, it has been investigated the role played by dance, as a body language that allows the symbolic expressions on the memory’s building and development in Down’s Syndrome individuals. Therefore, a single group with three Down individuals was formed, aged between 9 and 12 years old, regularly enrolled in a APAE. It has been held 20 intervention meetings in order to identify and analyze, if there were changes in the subjects’s actions, from their movements, body and oral expressions throughout the intervention process. Thinking about the whole process of conducting this research, we’ve noticed that one of the consistent findings we’ve got is that, when we point out the subjects’s biological difficulties and we’ve agreed on them, we could, despite of the contradictions imposed by the social and educational reality, say that subject’s biological laws can be overcome from the social relations that one establishes in the course of his life, since the Down’s Syndrome subjects own the capacity to develop their psychic ability, even if slowly, and therefore, proceed from the interventions allowed by the physical education teacher, to propose the dance as an educational ctivity.

  20. [The ideal body: media pedagogy].

    Science.gov (United States)

    Ribeiro, Rubia Guimarães; da Silva, Karen Schein; Kruse, Maria Henriqueta Luce

    2009-03-01

    We present enunciations that circulate in the media regarding the body, discussing the ways in which the speeches related with the maintenance of health and aesthetics invest in its improvement. Therefore, we used the Caderno Vida, a weekly insert of Zero Hora, for we understand it as owner of a proper speech that has the power of subjectivate people The analysis is part of Cultural Studies and it is based on the ideas of Michel Foucault. The methodological strategy used was the speech analysis of subjects about body care. The periodical questions its readers using speeches that point to beauty health and success The constructed categories were: how is the ideal body, what to do to have such body and why we must have this body Balanced feeding, practice of regular physical activities and the accomplishment of plastic surgeries are recommendations recurrently found in weekly inserts.