Sample records for activation analysis applications

  1. Neutron Activation Analysis: Techniques and Applications (United States)

    MacLellan, Ryan


    The role of neutron activation analysis in low-energy low-background experimentsis discussed in terms of comparible methods. Radiochemical neutron activation analysis is introduce. The procedure of instrumental neutron activation analysis is detailed especially with respect to the measurement of trace amounts of natural radioactivity. The determination of reactor neutron spectrum parameters required for neutron activation analysis is also presented.

  2. Application of prompt gamma-ray activation analysis

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    Chung, Yong Sam; Park, Kwang Won; Moon, Jong Hwa; Kim, Sun Ha; Baek, Sung Ryel [Korea Atomic Energy Research Institute, Taejeon (Korea)


    This technical report is written for the promotion to utilization of prompt gamma-ray activation analysis facility to be installed in HANARO reactor. It is described for a practical aspects including experiment and equipments, methodology, current status of the research and development and its applications. 102 refs., 32 figs., 25 tabs. (Author)

  3. Some Applications of Fast Neutron Activation Analysis of Oxygen

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    Owrang, Farshid


    In this thesis we focus on applications of neutron activation of oxygen for several purposes: A) measuring the water level in a laboratory tank, B) measuring the water flow in a pipe system set-up, C) analysing the oxygen in combustion products formed in a modern gasoline SI engine, and D) measuring on-line the amount of oxygen in bulk liquids. A) Water level measurements. The purpose of this work was to perform radiation based water level measurements, aimed at nuclear reactor vessels, on a laboratory scale. A laboratory water tank was irradiated by fast neutrons from a neutron generator. The water was activated at different water levels and the water level was decreased. The produced gamma radiation was measured using two detectors at different heights. The results showed that the method is suitable for measurement of water level and that a relatively small experimental set-up can be used for developing methods for water level measurements in real boiling water reactors based on activated oxygen in the water. B) Water flows in pipe. The goal in this work was to investigate the asymmetric distribution of activity in flow measurements with pulsed neutron activation (PNA) in a laboratory piping system. Earlier investigations had shown a discrepancy between the measured velocity of the activated water by PNA and the true mean velocity in the pipe. This discrepancy decreased with larger distances from the activation point. It was speculated that the induced activity in the pipe did not distribute homogeneously. With inhomogeneous radial distribution of activity in combination with a velocity profile in the pipe, the activated water may not have the same velocity as the mean velocity of water in the pipe. To study this phenomenon, a water-soluble colour was injected into a transparent pipe for simulation of the transport of the activated water. The radial concentration of the colour, at different distances from the activation point, was determined. The result

  4. Medical application of in vivo neutron activation analysis

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    Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Zanzi, I.; Aloia, J.F.


    The clinical usefulness of total body neutron activation analysis (TBNAA) was clearly established at an IAEA panel meeting in Vienna in 1972. It is best demonstrated by the studies involving the measurement of total-body calcium. This measurement provides data useful for the diagnosis and management of metabolic bone disorders. It should be emphasized, however, that while most of the applications to date have involved calcium and phosphorus, the measurement of sodium, chlorine and nitrogen also appear to be useful clinically. Total-body calcium measurements utilizing TBNAA have been used in studies of osteoporosis to establish absolute and relative deficits of calcium in patients with this disease in comparison to a normal contrast population. Changes in total-body calcium (skeletal mass) have also been useful for quantitating the efficacy of various therapies in osteoporosis. Serial measurements over periods of years provide long-term balance data by direct measurement with a higher precision (+- 2%) than is possible by the use of any other technique. In the renal osteodystrophy observed in patients with renal failure, disorders of both calcium and phosphorus, as well as electrolyte disturbances, have been studied. The measure of total-body levels of these elements gives the clinician useful data upon which to design dialysis therapy. The measurement of bone changes in endocrine dysfunction has been studied, particularly in patients with thyroid and parathyroid disorders. In parathyroidectomy, the measurement of total-body calcium, post-operatively, can indicate the degree of bone resorption. Skeletal metabolism and body composition in acromegaly and Cushing's disease have also been investigated by TBNAA. Levels of cadmium in liver and kidney have also been measured in-vivo by prompt-gamma neutron activation and associated with hypertension, emphysema and cigarette smoking.

  5. Application of thermal analysis techniques in activated carbon production (United States)

    Donnals, G.L.; DeBarr, J.A.; Rostam-Abadi, M.; Lizzio, A.A.; Brady, T.A.


    Thermal analysis techniques have been used at the ISGS as an aid in the development and characterization of carbon adsorbents. Promising adsorbents from fly ash, tires, and Illinois coals have been produced for various applications. Process conditions determined in the preparation of gram quantities of carbons were used as guides in the preparation of larger samples. TG techniques developed to characterize the carbon adsorbents included the measurement of the kinetics of SO2 adsorption, the performance of rapid proximate analyses, and the determination of equilibrium methane adsorption capacities. Thermal regeneration of carbons was assessed by TG to predict the life cycle of carbon adsorbents in different applications. TPD was used to determine the nature of surface functional groups and their effect on a carbon's adsorption properties.

  6. Diagnostic Application of Absolute Neutron Activation Analysis in Hematology

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    Zamboni, C.B.; Oliveira, L.C.; Dalaqua, L. Jr.


    The Absolute Neutron Activation Analysis (ANAA) technique was used to determine element concentrations of Cl and Na in blood of healthy group (male and female blood donators), select from Blood Banks at Sao Paulo city, to provide information which can help in diagnosis of patients. This study permitted to perform a discussion about the advantages and limitations of using this nuclear methodology in hematological examinations.

  7. Clinical applications of in vivo neutron-activation analysis

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    Cohn, S.H.


    In vivo neutron activation has opened a new era of both clinical diagnosis and therapy evaluation, and investigation into and modelling of body composition. The techniques are new, but it is already clear that considerable strides can be made in increasing accuracy and precision, increasing the number of elements susceptible to measurement, enhancing uniformity, and reducing the dose required for the measurement. The work presently underway will yield significant data on a variety of environmental contaminants such as Cd. Compositional studies are determining the level of vital constituents such as nitrogen and potassium in both normal subjects and in patients with a variety of metabolic disorders. Therapeutic programs can be assessed while in progress.

  8. Studies on application of radiation and radioisotopes -Studies on application of neutron activation analysis-

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    Jung, Yong Sam; Jung, Yung Joo; Jung, Eui Sik; Lee, Sang Mee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Kim, Nak Bae [Korea Institute of Geology, Mining and Materials, Taejon (Korea, Republic of)


    To apply Neutron activation analysis to routine analysis of environmental samples utilizing the research reactor (TRIGA MK-III), improving effects of analytical sensitivity have been investigated using both of thermal and epithermal neutron irradiating technique. Identification and development of analytical procedure was carried out using three kinds of standard reference materials (urban particulate matter, coal fly ash, soil). In addition, the confidence of this method was established by participation in collaborative research for the training and apply of international credit of analytical procedure. Practical studies on air dust samples have also been carried out regionally and seasonally. For the investigation on emission source of special element, enrichment factor was calculated in urban and rural area. Besides, a suitable process of biological sample (pine needle) analyses has been established by carrying out identification of uncertainty using standard reference material. The concentration of elements in practical samples were also determined regionally and seasonally. 14 figs, 26 tabs, 67 refs. (Author).

  9. Aqueous Humor Antimicrobial Activity: In Vitro Analysis after Topical 0.5% Chloramphenicol Application. (United States)

    Cagini, Carlo; Dragoni, Annalisa; Orsolini, Giampaolo; Fiore, Tito; Beccasio, Alfredo; Spadea, Leopoldo; Moretti, Amedeo; Mencacci, Antonella


    To assess aqueous humor antimicrobial activity in vitro after topical 0.5% chloramphenicol application. This investigation included 63 eyes from 65 cataract surgery patients. The study group of 48 eyes received preoperatively four topical applications of 0.5% chloramphenicol. The control group of 15 eyes was given no topical applications. Aqueous humor samples were collected for in vitro antimicrobial analysis using Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Pasteurella multocida organisms by means of disk diffusion test. No inhibition halo was observed around all aqueous humor samples from all chloramphenicol-treated patients, irrespective of the sample quantity added to the paper disks, with no significant difference from aqueous humor from untreated control patients. Aqueous humor displayed no bactericidal effect against any of the microorganisms evaluated after topical 0.5% chloramphenicol application.

  10. Neutron Activation Analysis

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    Corliss, William R.


    In activation analysis, a sample of an unknown material is first irradiated (activated) with nuclear particles. In practice these nuclear particles are almost always neutrons. The success of activation analysis depends upon nuclear reactions which are completely independent of an atom's chemical associations. The value of activation analysis as a research tool was recognized almost immediately upon the discovery of artificial radioactivity. This book discusses activation analysis experiments, applications and technical considerations.

  11. New generation non-stationary portable neutron generators for biophysical applications of Neutron Activation Analysis. (United States)

    Marchese, N; Cannuli, A; Caccamo, M T; Pace, C


    Neutron sources are increasingly employed in a wide range of research fields. For some specific purposes an alternative to existing large-scale neutron scattering facilities, can be offered by the new generation of portable neutron devices. This review reports an overview for such recently available neutron generators mainly addressed to biophysics applications with specific reference to portable non-stationary neutron generators applied in Neutron Activation Analysis (NAA). The review reports a description of a typical portable neutron generator set-up addressed to biophysics applications. New generation portable neutron devices, for some specific applications, can constitute an alternative to existing large-scale neutron scattering facilities. Deuterium-Deuterium pulsed neutron sources able to generate 2.5MeV neutrons, with a neutron yield of 1.0×10(6)n/s, a pulse rate of 250Hz to 20kHz and a duty factor varying from 5% to 100%, when combined with solid-state photon detectors, show that this kind of compact devices allow rapid and user-friendly elemental analysis. "This article is part of a Special Issue entitled "Science for Life" Guest Editor: Dr. Austen Angell, Dr. Salvatore Magazù and Dr. Federica Migliardo". Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Improvements and applications of neutron activation analysis using the monostandard method

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    Takeuchi, Takayuki (Kyoto Univ., Kumatori, Osaka (Japan). Research Reactor Inst.)


    Neutron activation analysis using the monostandard method is improved for broad application by compiling the necessary data, especially, selecting thermal neutron cross-sections and resonance integrals, and by investigating some sources of errors in neutron activation analysis; neutron flux self-shielding, dead time correction and losses of volatile elements. The self-shielding effects of thermal neutron flux and epithermal neutron flux are examined. The maximum permissible weight is given for each element of which the absorption thermal cross-section or the absorption resonance integral is greater than 100 b. Several correction methods for dead time of a multichannel analyser are checked experimentally and limits of application of those methods are discussed. Volatilization losses of mercury before, during and after neutron irradiation and the losses of chlorine, bromine and iodine during the irradiation are examined. The reagents which should be added to the standard to suppress the volatilization of mercury, are investigated. The monostandard method has been applied to the analyses of biological materials and archaeological samples. The NBS standard reference materials: Orchard Leaves and Bovine Liver are analysed and the results are compared with literature values. Ancient pigments of murals in the Takamatsu-zuka Tumulus are also analysed by the method. Archaeological meanings of those elemental concentrations are discussed.

  13. Introducing Spectral Structure Activity Relationship (S-SAR Analysis. Application to Ecotoxicology

    Directory of Open Access Journals (Sweden)

    Ana-Maria Lacrămă


    Full Text Available A novel quantitative structure-activity (property relationship model, namelySpectral-SAR, is presented in an exclusive algebraic way replacing the old-fashionedmulti-regression one. The actual S-SAR method interprets structural descriptors as vectorsin a generic data space that is further mapped into a full orthogonal space by means of theGram-Schmidt algorithm. Then, by coordinated transformation between the data andorthogonal spaces, the S-SAR equation is given under simple determinant form for anychemical-biological interactions under study. While proving to give the same analyticalequation and correlation results with standard multivariate statistics, the actual S-SARframe allows the introduction of the spectral norm as a valid substitute for the correlationfactor, while also having the advantage to design the various related SAR models throughthe introduced “minimal spectral path” rule. An application is given performing a completeS-SAR analysis upon the Tetrahymena pyriformis ciliate species employing its reportedeco-toxicity activities among relevant classes of xenobiotics. By representing the spectralnorm of the endpoint models against the concerned structural coordinates, the obtainedS-SAR endpoints hierarchy scheme opens the perspective to further design the eco-toxicological test batteries with organisms from different species.

  14. Application of neutron activation analysis system in Xi'an pulsed reactor

    CERN Document Server

    Zhang Wen Shou; Yu Qi


    Neutron Activation Analysis System in Xi'an Pulsed Reactor is consist of rabbit fast radiation system and experiment measurement system. The functions of neutron activation analysis are introduced. Based on the radiation system. A set of automatic data handling and experiment simulating system are built. The reliability of data handling and experiment simulating system had been verified by experiment

  15. How Gamification Affects Physical Activity: Large-scale Analysis of Walking Challenges in a Mobile Application. (United States)

    Shameli, Ali; Althoff, Tim; Saberi, Amin; Leskovec, Jure


    Gamification represents an effective way to incentivize user behavior across a number of computing applications. However, despite the fact that physical activity is essential for a healthy lifestyle, surprisingly little is known about how gamification and in particular competitions shape human physical activity. Here we study how competitions affect physical activity. We focus on walking challenges in a mobile activity tracking application where multiple users compete over who takes the most steps over a predefined number of days. We synthesize our findings in a series of game and app design implications. In particular, we analyze nearly 2,500 physical activity competitions over a period of one year capturing more than 800,000 person days of activity tracking. We observe that during walking competitions, the average user increases physical activity by 23%. Furthermore, there are large increases in activity for both men and women across all ages, and weight status, and even for users that were previously fairly inactive. We also find that the composition of participants greatly affects the dynamics of the game. In particular, if highly unequal participants get matched to each other, then competition suffers and the overall effect on the physical activity drops significantly. Furthermore, competitions with an equal mix of both men and women are more effective in increasing the level of activities. We leverage these insights to develop a statistical model to predict whether or not a competition will be particularly engaging with significant accuracy. Our models can serve as a guideline to help design more engaging competitions that lead to most beneficial behavioral changes.

  16. Application of COMSOL Multiphysics in Thermal Effect Analysis of Electromagnetic Active Vibration Absorber (United States)

    Hang, Su; Xue-tao, Weng


    At present, there are some researches in the thermal analysis of electromagnetic absorbers. The heating principle of electromagnetic absorber magnetic circuit is analysed, and the finite element method is used to numerically solve the temperature field in the working process of electromagnetic vibration absorber. The magnetic circuit simulation model of electromagnetic vibration absorber is established in Comsol Multiphysics finite element analysis software. And the grid Division, simulation analysis of the vibration absorber magnetic circuit structure of the internal temperature distribution, you can get the vibration absorber magnetic circuit in the working process of the temperature field of two-dimensional distribution graphics and magnetic circuit structure of different parts of the temperature rise contrast chart. The conclusion provides some theoretical reference for the design and research of electromagnetic active vibration absorber.

  17. Activation analysis study on Li-ion batteries for nuclear forensic applications

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    Johnson, Erik B., E-mail: [Radiation Monitoring Devices Inc., 44 Hunt Street, Watertown, MA 02472 (United States); Whitney, Chad [Radiation Monitoring Devices Inc., 44 Hunt Street, Watertown, MA 02472 (United States); Holbert, Keith E.; Zhang, Taipeng; Stannard, Tyler; Christie, Anthony; Harper, Peter; Anderson, Blake [Arizona State University, Tempe, AZ 85287 (United States); Christian, James F. [Radiation Monitoring Devices Inc., 44 Hunt Street, Watertown, MA 02472 (United States)


    The nuclear materials environment has been increasing significantly in complexity over the past couple of decades. The prevention of attacks from nuclear weapons is becoming more difficult, and nuclear forensics is a deterrent by providing detailed information on any type of nuclear event for proper attribution. One component of the nuclear forensic analysis is a measurement of the neutron spectrum. As an example, the neutron component provides information on the composition of the weapons, whether boosting is involved or the mechanisms used in creating a supercritical state. As {sup 6}Li has a large cross-section for thermal neutrons, the lithium battery is a primary candidate for assessing the neutron spectrum after detonation. The absorption process for {sup 6}Li yields tritium, which can be measured at a later point after the nuclear event, as long as the battery can be processed in a manner to successfully extract the tritium content. In addition, measuring the activated constituents after exposure provides a means to reconstruct the incident neutron spectrum. The battery consists of a spiral or folded layers of material that have unique, energy dependent interactions associated with the incident neutron flux. A detailed analysis on the batteries included a pre-irradiated mass spectrometry analysis to be used as input for neutron spectrum reconstruction. A set of batteries were exposed to a hard neutron spectrum delivered by the University of Massachusetts, Lowell research reactor Fast Neutron Irradiator (FNI). The gamma spectra were measured from the batteries within a few days and within a week after the exposure to obtain sufficient data on the activated materials in the batteries. The activity was calculated for a number of select isotopes, indicating the number of associated neutron interactions. The results from tritium extraction are marginal. A measurable increase in detected particles (gammas and betas) below 50 keV not self-attenuated by the battery

  18. Cross-spectral analysis of physiological tremor and muscle activity; 2, Application to synchronized EMG

    CERN Document Server

    Timmer, J; Pfleger, W; Deuschl, G


    We investigate the relationship between synchronized muscle activity and tremor time series in (enhanced) physiological tremor by cross-spectral analysis. Special attention is directed to the phase spectrum and its possibilities to clarify the contribution of reflex mechanisms to physiological tremor. The phase spectra are investigated under the assumptions that the EMG synchronization was caused by a reflex, respectively a central oscillator. In comparison of these results to phase spectra of measured data we found a significant contribution of reflexes. But reflexes only modify existing peaks in the power spectrum. The main agents of physiological tremor are an efferent pace and the resonant behavior of the biomechanical system.

  19. Joint Wavelet Video Denoising and Motion Activity Detection in Multimodal Human Activity Analysis: Application to Video-Assisted Bioacoustic/Psychophysiological Monitoring (United States)

    Dimoulas, C. A.; Avdelidis, K. A.; Kalliris, G. M.; Papanikolaou, G. V.


    The current work focuses on the design and implementation of an indoor surveillance application for long-term automated analysis of human activity, in a video-assisted biomedical monitoring system. Video processing is necessary to overcome noise-related problems, caused by suboptimal video capturing conditions, due to poor lighting or even complete darkness during overnight recordings. Modified wavelet-domain spatiotemporal Wiener filtering and motion-detection algorithms are employed to facilitate video enhancement, motion-activity-based indexing and summarization. Structural aspects for validation of the motion detection results are also used. The proposed system has been already deployed in monitoring of long-term abdominal sounds, for surveillance automation, motion-artefacts detection and connection with other psychophysiological parameters. However, it can be used to any video-assisted biomedical monitoring or other surveillance application with similar demands.

  20. Cluster analysis for applications

    CERN Document Server

    Anderberg, Michael R


    Cluster Analysis for Applications deals with methods and various applications of cluster analysis. Topics covered range from variables and scales to measures of association among variables and among data units. Conceptual problems in cluster analysis are discussed, along with hierarchical and non-hierarchical clustering methods. The necessary elements of data analysis, statistics, cluster analysis, and computer implementation are integrated vertically to cover the complete path from raw data to a finished analysis.Comprised of 10 chapters, this book begins with an introduction to the subject o

  1. Some applications of neutron activation analysis in plant biology and agronomy; Quelques applications de l'analyse par radioactivation neutronique en biologie vegetale et en agronomie

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    Fourcy, A. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires


    Plants materials are not so commonly analysed by radioactivation than biological extracts of medical importance. With help of concrete examples, applications of neutrons activation analysis to the determination of some metals (Mn, Cu, Co, Fe, Zn, and K) in plant materials, are proposed. Samples are activated in a swimming-pool reactor at the thermal flux of 5.10{sup 12}{sup -2}s{sup -1} for a time varying between few minutes and several days according to the element being analysed. The induced radioactivity is measured by spectrometry, with radiochemical separation ( Cu, Co, Fe, Zn and K) or without separation in best cases (Mn,Cu, K). Described dosages are related to: manganese in a graminaceous plant, copper in vine treatments, cobalt, iron and zinc in animal feeding, potassium in a radiological experiment. (author) [French] Les produits vegetaux sont beaucoup moins souvent soumis a l'analyse par activation que les extraits biologiques d'interet medical. En s'appuyant sur des cas concrets, nous proposons des applications de l'analyse par activation neutronique au dosage de differents metaux (Mn, Cu, Co, Fe, Zn, et K) dans la matiere vegetale. Les echantillons sont actives en pile piscine au flux thermique de 5.10{sup 12}{sup -2} s{sup -1} pendant des temps variant de quelques minutes a plusieurs jours selon les elements a analyser. le comptage de la radioactivite induite est effectue par spectrometrie gamma apres separation radiochimique (Cu, Co, Fe, Zn, et K) ou sans separation dans les cas favorables (Mn, Cu, K). Les dosages decrits concernent: le manganese dans une graminee, le cuivre en viticulture, le cobalt, le fer, et le zinc dans un aliment du betail, le potassium dans une experience de radioecologie. (auteur)

  2. Analysis of an application degree of marketing in organization and management activity of youth sports schools

    Directory of Open Access Journals (Sweden)

    N.V. Sereda


    Full Text Available Disclosed aspects of the marketing approach in the activities of youth sports schools. The degree of use of marketing in the organization and management of youth sports schools. Identified constraints and the possible consequences of the use of marketing in youth sports schools. The study involved 127 employees with 15 youth sports schools. The respondents were the director and deputy instructor methodists that senior coaches offices youth sports schools. It is certain that in their professional activities only 36.0% of workers in youth sports schools use marketing is the marketing research, 73.2% of respondents believe that the use of marketing to promote the image of youth sports schools. The absence of a marketing specialist in the management bodies of physical education and sport is one of the main problems for the efficient functioning of the market of sports schools sports and sports services.



    Struett, Mirian Aparecida Micarelli; Souza, Antônio Artur de; Raimundini, Simone Letícia


    Brazilian hospital organizations are beginners when it comes to using managing tools. Under these circumstances, cost information becomes essential to the decision making process regarding their financial and operational management. Activity based costing is an example of such tools. Few publications describe researches on the use of this costing method in hospitals. However, there are no reports in the Brazilian hospital literature showing they have ever taken advantage of the use of this co...

  4. Application of artificial neural network in precise prediction of cement elements percentages based on the neutron activation analysis (United States)

    Eftekhari Zadeh, E.; Feghhi, S. A. H.; Roshani, G. H.; Rezaei, A.


    Due to variation of neutron energy spectrum in the target sample during the activation process and to peak overlapping caused by the Compton effect with gamma radiations emitted from activated elements, which results in background changes and consequently complex gamma spectrum during the measurement process, quantitative analysis will ultimately be problematic. Since there is no simple analytical correlation between peaks' counts with elements' concentrations, an artificial neural network for analyzing spectra can be a helpful tool. This work describes a study on the application of a neural network to determine the percentages of cement elements (mainly Ca, Si, Al, and Fe) using the neutron capture delayed gamma-ray spectra of the substance emitted by the activated nuclei as patterns which were simulated via the Monte Carlo N-particle transport code, version 2.7. The Radial Basis Function (RBF) network is developed with four specific peaks related to Ca, Si, Al and Fe, which were extracted as inputs. The proposed RBF model is developed and trained with MATLAB 7.8 software. To obtain the optimal RBF model, several structures have been constructed and tested. The comparison between simulated and predicted values using the proposed RBF model shows that there is a good agreement between them.

  5. Active learning-based information structure analysis of full scientific articles and two applications for biomedical literature review. (United States)

    Guo, Yufan; Silins, Ilona; Stenius, Ulla; Korhonen, Anna


    Techniques that are capable of automatically analyzing the information structure of scientific articles could be highly useful for improving information access to biomedical literature. However, most existing approaches rely on supervised machine learning (ML) and substantial labeled data that are expensive to develop and apply to different sub-fields of biomedicine. Recent research shows that minimal supervision is sufficient for fairly accurate information structure analysis of biomedical abstracts. However, is it realistic for full articles given their high linguistic and informational complexity? We introduce and release a novel corpus of 50 biomedical articles annotated according to the Argumentative Zoning (AZ) scheme, and investigate active learning with one of the most widely used ML models-Support Vector Machines (SVM)-on this corpus. Additionally, we introduce two novel applications that use AZ to support real-life literature review in biomedicine via question answering and summarization. We show that active learning with SVM trained on 500 labeled sentences (6% of the corpus) performs surprisingly well with the accuracy of 82%, just 2% lower than fully supervised learning. In our question answering task, biomedical researchers find relevant information significantly faster from AZ-annotated than unannotated articles. In the summarization task, sentences extracted from particular zones are significantly more similar to gold standard summaries than those extracted from particular sections of full articles. These results demonstrate that active learning of full articles' information structure is indeed realistic and the accuracy is high enough to support real-life literature review in biomedicine. The annotated corpus, our AZ classifier and the two novel applications are available at

  6. Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis. (United States)

    Gaspar, Paulo; Kallemeijn, Wouter W; Strijland, Anneke; Scheij, Saskia; Van Eijk, Marco; Aten, Jan; Overkleeft, Herman S; Balreira, Andrea; Zunke, Friederike; Schwake, Michael; Sá Miranda, Clara; Aerts, Johannes M F G


    Lysosomal integral membrane protein-2 (LIMP2) mediates trafficking of glucocerebrosidase (GBA) to lysosomes. Deficiency of LIMP2 causes action myoclonus-renal failure syndrome (AMRF). LIMP2-deficient fibroblasts virtually lack GBA like the cells of patients with Gaucher disease (GD), a lysosomal storage disorder caused by mutations in the GBA gene. While GD is characterized by the presence of glucosylceramide-laden macrophages, AMRF patients do not show these. We studied the fate of GBA in relation to LIMP2 deficiency by employing recently designed activity-based probes labeling active GBA molecules. We demonstrate that GBA is almost absent in lysosomes of AMRF fibroblasts. However, white blood cells contain considerable amounts of residual enzyme. Consequently, AMRF patients do not acquire lipid-laden macrophages and do not show increased plasma levels of macrophage markers, such as chitotriosidase, in contrast to GD patients. We next investigated the consequences of LIMP2 deficiency with respect to plasma glycosphingolipid levels. Plasma glucosylceramide concentration was normal in the AMRF patients investigated as well as in LIMP2-deficient mice. However, a marked increase in the sphingoid base, glucosylsphingosine, was observed in AMRF patients and LIMP2-deficient mice. Our results suggest that combined measurements of chitotriosidase and glucosylsphingosine can be used for convenient differential laboratory diagnosis of GD and AMRF.

  7. Cost Analysis of MRI Services in Iran: An Application of Activity Based Costing Technique. (United States)

    Bayati, Mohsen; Mahboub Ahari, Alireza; Badakhshan, Abbas; Gholipour, Mahin; Joulaei, Hassan


    Considerable development of MRI technology in diagnostic imaging, high cost of MRI technology and controversial issues concerning official charges (tariffs) have been the main motivations to define and implement this study. The present study aimed to calculate the unit-cost of MRI services using activity-based costing (ABC) as a modern cost accounting system and to fairly compare calculated unit-costs with official charges (tariffs). We included both direct and indirect costs of MRI services delivered in fiscal year 2011 in Shiraz Shahid Faghihi hospital. Direct allocation method was used for distribution of overhead costs. We used micro-costing approach to calculate unit-cost of all different MRI services. Clinical cost data were retrieved from the hospital registering system. Straight-line method was used for depreciation cost estimation. To cope with uncertainty and to increase the robustness of study results, unit costs of 33 MRI services was calculated in terms of two scenarios. Total annual cost of MRI activity center (AC) was calculated at USD 400,746 and USD 532,104 based on first and second scenarios, respectively. Ten percent of the total cost was allocated from supportive departments. The annual variable costs of MRI center were calculated at USD 295,904. Capital costs measured at USD 104,842 and USD 236, 200 resulted from the first and second scenario, respectively. Existing tariffs for more than half of MRI services were above the calculated costs. As a public hospital, there are considerable limitations in both financial and administrative databases of Shahid Faghihi hospital. Labor cost has the greatest share of total annual cost of Shahid Faghihi hospital. The gap between unit costs and tariffs implies that the claim for extra budget from health providers may not be relevant for all services delivered by the studied MRI center. With some adjustments, ABC could be implemented in MRI centers. With the settlement of a reliable cost accounting system

  8. Cost Analysis of MRI Services in Iran: An Application of Activity Based Costing Technique (United States)

    Bayati, Mohsen; Mahboub Ahari, Alireza; Badakhshan, Abbas; Gholipour, Mahin; Joulaei, Hassan


    Background: Considerable development of MRI technology in diagnostic imaging, high cost of MRI technology and controversial issues concerning official charges (tariffs) have been the main motivations to define and implement this study. Objectives: The present study aimed to calculate the unit-cost of MRI services using activity-based costing (ABC) as a modern cost accounting system and to fairly compare calculated unit-costs with official charges (tariffs). Materials and Methods: We included both direct and indirect costs of MRI services delivered in fiscal year 2011 in Shiraz Shahid Faghihi hospital. Direct allocation method was used for distribution of overhead costs. We used micro-costing approach to calculate unit-cost of all different MRI services. Clinical cost data were retrieved from the hospital registering system. Straight-line method was used for depreciation cost estimation. To cope with uncertainty and to increase the robustness of study results, unit costs of 33 MRI services was calculated in terms of two scenarios. Results: Total annual cost of MRI activity center (AC) was calculated at USD 400,746 and USD 532,104 based on first and second scenarios, respectively. Ten percent of the total cost was allocated from supportive departments. The annual variable costs of MRI center were calculated at USD 295,904. Capital costs measured at USD 104,842 and USD 236, 200 resulted from the first and second scenario, respectively. Existing tariffs for more than half of MRI services were above the calculated costs. Conclusion: As a public hospital, there are considerable limitations in both financial and administrative databases of Shahid Faghihi hospital. Labor cost has the greatest share of total annual cost of Shahid Faghihi hospital. The gap between unit costs and tariffs implies that the claim for extra budget from health providers may not be relevant for all services delivered by the studied MRI center. With some adjustments, ABC could be implemented in MRI


    Directory of Open Access Journals (Sweden)

    Ilya V. Samarin


    Full Text Available The technique of application of a method of the analysis of hierarchiesfor the solution of problems of monitoring of activity of the enterprise onadvance to a strategic objective in the course of implementation of thecurrent medium-term plan is presented. Problems of an assessment of astate and situation forecasting to the termination of the current planningperiod are considered. The matrix method which is the return method ofthe analysis of hierarchies, allowing to estimate and predict a situationwith implementation of the plan in all structures of the enterprise andrealizing procedure of strategic monitoring at the enterprise is developed. Statistical and analytical methods of the solution of a problemof forecasting are presented. For the solution of a task the statisticalmethod developed algorithm of the numerical solution of a task and itsflowchart is submitted. An algorithm for solving the problem of determination of the integral strategic risk the implementation of the set ofevents. Shows an example of solving the problem of determination ofthe degree of achievement of the intermediate objectives for the knownvalues of the degree of implementation of all stipulated by a plan ofactions (works for the six-level hierarchical scheme.

  10. Analysis, Modeling, and Simulation (AMS) Testbed Development and Evaluation to Support Dynamic Mobility Applications (DMA) and Active Transportation and Demand Management (ATDM) Programs - San Mateo Testbed Analysis Plan [supporting datasets - San Mateo Testbed (United States)


    This zip file contains files of data to support FHWA-JPO-16-370, Analysis, Modeling, and Simulation (AMS) Testbed Development and Evaluation to Support Dynamic Mobility Applications (DMA) and Active Transportation and Demand Management (ATDM) Program...

  11. Extracurricular activities of medical school applicants. (United States)

    Kim, Sang Hyun


    The purpose of this study was to investigate medical school applicants' involvements in extracurricular activities including medical volunteering/community services, nonmedical community services, club activities, leadership role, and research. Extracurricular characteristics were compared for 448 applicants (223 males and 225 females) who applied to Kangwon Medical School in 2013 to 2014. Frequency analysis, chi-square test, and simple correlation were conducted with the collected data. The 448 applicants participated in medical volunteer/community services (15.3%), nonmedical community services (39.8%), club activities (22.9%), club officials (10%), and research (13.4%). On average, applicants from foreign universities participated in 0.9 medical volunteer/community service, 0.8 nonmedical community service, 1.7 club activities, and 0.6 research work. On the other hand, applicants from domestic universities reported 0.2 medical volunteer/community service, 1.0 nonmedical community service, 0.7 club activity, and 0.3 research. Involvement in extracurricular activities was extensive for medical school applicants. Participation in extracurricular activities differed between applicants from foreign and domestic universities. Females consistently reported greater participation in extracurricular activities than males. The data can be helpful for admission committees to recruit well-rounded applicants and compare between applicants with similar academic backgrounds.

  12. Flow of Funds Modeling for Localized Financial Markets: An Application of Spatial Price and Allocation Activity Analysis Models. (United States)


    116 Market linkages 124 Prototypes for Product Differentiation 129 Advertising 133 Collusion and leading firm solutions 135 Monopolistic segmentation and product differentiation ; government 5 regulation and intervention; and competition not only in marketing final products, loans and...Prototypes for Product Differentiation The spatial price and allocation activity analysis model has been used to demonstrate the perfect competition

  13. Discriminating brain activity from task-related artifacts in functional MRI: fractal scaling analysis simulation and application. (United States)

    Lee, Jae-Min; Hu, Jing; Gao, Jianbo; Crosson, Bruce; Peck, Kyung K; Wierenga, Christina E; McGregor, Keith; Zhao, Qun; White, Keith D


    Functional magnetic resonance imaging (fMRI) signal changes can be separated from background noise by various processing algorithms, including the well-known deconvolution method. However, discriminating signal changes due to task-related brain activities from those due to task-related head motion or other artifacts correlated in time to the task has been little addressed. We examine whether three exploratory fractal scaling analyses correctly classify these possibilities by capturing temporal self-similarity; namely, fluctuation analysis, wavelet multi-resolution analysis, and detrended fluctuation analysis (DFA). We specifically evaluate whether these fractal analytic methods can be effective and reliable in discriminating activations from artifacts. DFA is indeed robust for such classification. Brain activation maps derived by DFA are similar, but not identical, to maps derived by deconvolution. Deconvolution explicitly utilizes task timing to extract the signals whereas DFA does not, so these methods reveal somewhat different information from the data. DFA is better than deconvolution for distinguishing fMRI activations from task-related artifacts, although a combination of these approaches is superior to either one taken alone. We also present a method for estimating noise levels in fMRI data, validated with numerical simulations suggesting that Birn's model is effective for simulating fMRI signals. Simulations further corroborate that DFA is excellent at discriminating signal changes due to task-related brain activities from those due to task-related artifacts, under a range of conditions.

  14. Control and dynamic analysis of a parallel-connected single active bridge DC-DC converter for DC-grid wind farm application

    DEFF Research Database (Denmark)

    Park, Kiwoo; Chen, Zhe


    This study presents a control strategy and its dynamic analysis of a high-power dc-dc converter, which is constructed with the parallel-connected single active bridge (SAB) dc-dc converters for dc-grid wind farm applications. The structural and operational characteristics of the SAB dc-dc convert...... for dc-grid wind farm applications, an input voltage control method based on the PI control will be introduced and the dynamics of the overall system will be analysed. The analysis results are to be verified by means of simulations and experiments.......This study presents a control strategy and its dynamic analysis of a high-power dc-dc converter, which is constructed with the parallel-connected single active bridge (SAB) dc-dc converters for dc-grid wind farm applications. The structural and operational characteristics of the SAB dc-dc converter...... have several advantages for high-power applications, and the modular concept of the parallel-connected converter is highly beneficial especially for offshore wind farm applications in terms of maintenance cost and fault tolerance. To justify the feasibility of the parallel-connected SAB dc-dc converter...

  15. Application of statistical process control and process capability analysis procedures in orbiter processing activities at the Kennedy Space Center (United States)

    Safford, Robert R.; Jackson, Andrew E.; Swart, William W.; Barth, Timothy S.


    Successful ground processing at KSC requires that flight hardware and ground support equipment conform to specifications at tens of thousands of checkpoints. Knowledge of conformance is an essential requirement for launch. That knowledge of conformance at every requisite point does not, however, enable identification of past problems with equipment, or potential problem areas. This paper describes how the introduction of Statistical Process Control and Process Capability Analysis identification procedures into existing shuttle processing procedures can enable identification of potential problem areas and candidates for improvements to increase processing performance measures. Results of a case study describing application of the analysis procedures to Thermal Protection System processing are used to illustrate the benefits of the approaches described in the paper.

  16. Characterization of the most aroma-active compounds in cherry tomato by application of the aroma extract dilution analysis. (United States)

    Selli, Serkan; Kelebek, Hasim; Ayseli, Mehmet Turan; Tokbas, Habip


    Aroma and aroma-active compounds of cherry tomato (Lycopersicum esculentum) was analyzed by gas chromatography-mass spectrometry-olfactometry (GC-MS-O). According to sensory analysis, the aromatic extract obtained by liquid-liquid extraction was representative of tomato odour. A total of 49 aroma compounds were identified and quantified in fresh cherry tomato. Aldehydes were qualitatively and quantitatively the most dominant volatiles in cherry tomato, followed by alcohols. Aroma extract dilution analysis (AEDA) was used for the determination of aroma-active compounds of tomato sample. A total of 21 aroma-active compounds were detected in aromatic extract of fresh tomato, of which 18 were identified. On the basis of the flavour dilution (FD) factor, the most powerful aroma-active compounds identified in the extract were (Z)-3-hexenal (FD=1024) and (E)-2-hexenal (FD=256), which were described as the strong green-grassy and green-leafy odour, respectively. The major organic acid and sugar found were citric acid and fructose, respectively. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Sight Application Analysis Tool

    Energy Technology Data Exchange (ETDEWEB)

    Bronevetsky, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    The scale and complexity of scientific applications makes it very difficult to optimize, debug and extend them to support new capabilities. We have developed a tool that supports developers’ efforts to understand the logical flow of their applications and interactions between application components and hardware in a way that scales with application complexity and parallelism.

  18. Application of synchrotron-radiation-based x-ray microprobe techniques for the analysis of recombination activity of metals precipitated at Si/SiGe misfit dislocations

    CERN Document Server

    Vyvenko, O F; Istratov, A A; Weber, E R; Kittler, M; Seifert, W


    In this study we report application of synchrotron-radiation-based x-ray microprobe techniques (the x-ray-beam-induced current (XBIC) and x-ray fluorescence (mu-XRF) methods) to the analysis of the recombination activity and space distribution of copper and iron in the vicinity of dislocations in silicon/silicon-germanium structures. A combination of these two techniques enables one to study the chemical nature of the defects and impurities and their recombination activity in situ and to map metal clusters with a micron-scale resolution. XRF analysis revealed that copper formed clearly distinguishable precipitates along the misfit dislocations. A proportional dependence between the XBIC contrast and the number of copper atoms in the precipitates was established. In hydrogen-passivated iron-contaminated samples we observed clusters of iron precipitates which had no recombination activity detectable by the XBIC technique as well as iron clusters which were not completely passivated.

  19. Improved techniques in data analysis and interpretation of potential fields: examples of application in volcanic and seismically active areas

    Directory of Open Access Journals (Sweden)

    G. Florio


    Full Text Available Geopotential data may be interpreted by many different techniques, depending on the nature of the mathematical equations correlating specific unknown ground parameters to the measured data set. The investigation based on the study of the gravity and magnetic anomaly fields represents one of the most important geophysical approaches in the earth sciences. It has now evolved aimed both at improving of known methods and testing other new and reliable techniques. This paper outlines a general framework for several applications of recent techniques in the study of the potential methods for the earth sciences. Most of them are here described and significant case histories are shown to illustrate their reliability on active seismic and volcanic areas.

  20. Cross-spectral analysis of physiological tremor and muscle activity; 1, Theory and application to unsynchronized EMG

    CERN Document Server

    Timmer, J; Pfleger, W; Deuschl, G


    We investigate the relationship between the extensor electromyogram (EMG) and tremor time series in physiological hand tremor by cross-spectral analysis. Special attention is directed to the phase spectrum and the effects of observational noise. We calculate the theoretical phase spectrum for a second order linear stochastic process and compare the results to measured tremor data recorded from subjects who did not show a synchronized EMG activity in the corresponding extensor muscle. The results show that physiological tremor is well described by the proposed model and that the measured EMG represents a Newtonian force by which the muscle acts on the hand.

  1. Application of Epithermal Neutron Activation Analysis to Investigate Accumulation and Adsorption of Mercury by Spirulina platensis Biomass

    CERN Document Server

    Mosulishvili, L M; Khizanishvili, A I; Frontasyeva, M V; Kirkesali, E I; Aksenova, N G


    Epithermal neutron activation analysis was used to study interaction of blue-green alga Spirulina platensis with toxic metal mercury. Various concentrations of Hg(II) were added to cell cultures in a nutrient medium. The dynamics of accumulation of Hg was investigated over several days in relation to Spirulina biomass growth. The process of Hg adsorption by Spirulina biomass was studied in short-time experiments. The isotherm of adsorption was carried out in Freindlich coordinates. Natural Spirulina biomass has potential to be used in the remediation of sewage waters at Hg concentrations \\sim 100 {\\mu}g/l.

  2. The Applications of GIS in the Analysis of the Impacts of Human Activities on South Texas Watersheds

    Directory of Open Access Journals (Sweden)

    Chandra Richardson


    Full Text Available With water resource planning assuming greater importance in environmental protection efforts, analyzing the health of agricultural watersheds using Geographic Information Systems (GIS becomes essential for decision-makers in Southern Texas. Within the area, there exist numerous threats from conflicting land uses. These include the conversion of land formerly designated for agricultural purposes to other uses. Despite current efforts, anthropogenic factors are greatly contributing to the degradation of watersheds. Additionally, the activities of waste water facilities located in some of the counties, rising populations, and other socioeconomic variables are negatively impacting the quality of water in the agricultural watersheds. To map the location of these stressors spatially and the extent of their impacts across time, the paper adopts a mix scale method of temporal spatial analysis consisting of simple descriptive statistics. In terms of objectives, this research provides geo-spatial analysis of the effects of human activities on agricultural watersheds in Southern Texas and the factors fuelling the concerns under the purview of watershed management. The results point to growing ecosystem decline across time and a geographic cluster of counties experiencing environmental stress. Accordingly, the emergence of stressors such as rising population, increased use of fertilizer treatments on farm land, discharges of atmospheric pollutants and the large presence of municipal and industrial waste treatment facilities emitting pathogens and pesticides directly into the agricultural watersheds pose a growing threat to the quality of the watershed ecosystem.

  3. The applications of GIS in the analysis of the impacts of human activities on south Texas watersheds. (United States)

    Merem, Edmund C; Yerramilli, Sudha; Twumasi, Yaw A; Wesley, Joan M; Robinson, Bennetta; Richardson, Chandra


    With water resource planning assuming greater importance in environmental protection efforts, analyzing the health of agricultural watersheds using Geographic Information Systems (GIS) becomes essential for decision-makers in Southern Texas. Within the area, there exist numerous threats from conflicting land uses. These include the conversion of land formerly designated for agricultural purposes to other uses. Despite current efforts, anthropogenic factors are greatly contributing to the degradation of watersheds. Additionally, the activities of waste water facilities located in some of the counties, rising populations, and other socioeconomic variables are negatively impacting the quality of water in the agricultural watersheds. To map the location of these stressors spatially and the extent of their impacts across time, the paper adopts a mix scale method of temporal spatial analysis consisting of simple descriptive statistics. In terms of objectives, this research provides geo-spatial analysis of the effects of human activities on agricultural watersheds in Southern Texas and the factors fuelling the concerns under the purview of watershed management. The results point to growing ecosystem decline across time and a geographic cluster of counties experiencing environmental stress. Accordingly, the emergence of stressors such as rising population, increased use of fertilizer treatments on farm land, discharges of atmospheric pollutants and the large presence of municipal and industrial waste treatment facilities emitting pathogens and pesticides directly into the agricultural watersheds pose a growing threat to the quality of the watershed ecosystem.

  4. Comparative Analysis of the Composition and Active Property Evaluation of Certain Essential Oils to Assess their Potential Applications in Active Food Packaging

    Directory of Open Access Journals (Sweden)

    Cornelia Vasile


    Full Text Available The antifungal, antibacterial, and antioxidant activity of four commercial essential oils (EOs (thyme, clove, rosemary, and tea tree from Romanian production were studied in order to assess them as bioactive compounds for active food packaging applications. The chemical composition of the oils was determined with the Folin–Ciocâlteu method and gas chromatography coupled with mass spectrometry and flame ionization detectors, and it was found that they respect the AFNOR/ISO standard limits. The EOs were tested against three food spoilage fungi—Fusarium graminearum, Penicillium corylophilum, and Aspergillus brasiliensis—and three potential pathogenic food bacteria—Staphylococcus aureus, Escherichia coli, and Listeria monocytogenes—using the disc diffusion method. It was found that the EOs of thyme, clove, and tea tree can be used as antimicrobial agents against the tested fungi and bacteria, thyme having the highest inhibitory effect. Concerning antioxidant activity determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH and 2,2’-azino-bis 3-ethylbenzthiazoline-6-sulfonic acid (ABTS methods, it has been established that the clove oil exhibits the highest activity because of its high phenolic content. Promising results were obtained by their incorporation into chitosan emulsions and films, which show potential for food packaging. Therefore, these essential oils could be suitable alternatives to chemical additives, satisfying the consumer demand for naturally preserved food products ensuring its safety.


    Directory of Open Access Journals (Sweden)

    Kigho Moses Oghenejoboh


    Full Text Available A comparative analysis of the efficiency of activated carbon produced from fermented cassava peels (CPB, unfermented cassava peels (CPA and commercial grade activated carbon (CAC in the treatment of refinery wastewater was carried out. CPB was found to be 8% and 18% more efficient when compared to CPA and CAC in the removal of COD, and 14% and 3% better than CAC and CPA respectively in the removal of BOD5. The removal efficiency of Pb2+ by CPB was 100% compared to 95% and 57% by CPA and CAC while 96% of phenol was removed by CPB against 93% and 83% by CPA and CAC respectively. This better performance of CPB over CPA and CAC is not unconnected with its higher pH resulting from the removal of cyanide from the peels during the fermentation process. However, despite the high phenol removal efficiency by CPB, the concentration of phenol in the treated effluent does not meet the environmental guidelines for disposal. It is therefore, recommended that a two-stage CPB adsorption column arranged in series is necessary to treat refinery wastewater efficiently if it is desired to totally remove phenol from the effluent or reduce the concentration to 0.005mg/l allowed by the Federal environmental protection agency (FEPA. The equilibrium adsorption test conducted showed that the Freundlich isotherm is a better fit for the adsorption of phenol by the three activated carbons with correlation coefficients (R2 of 0.9364, 0.9383 and 0.9541 for CAC, CPA and CPB respectively. CPB was found to be a better adsorbent as it has the highest adsorptive capacity as evidenced from its better Freundlich exponent.

  6. Application of a novel cold activated carbon fiber-solid phase microextraction for analysis of organochlorine pesticides in soil. (United States)

    Chai, Xiaolan; Jia, Jinping; Sun, Tonghua; Wang, Yalin; Liao, Liyan


    A novel and simple analytical procedure using cold activated carbon fiber-solid phase microextraction (CACF-SPME) was applied to determine organochlorine pesticides (OCs) in soil samples. The pesticides in this study consist of alpha -, beta -, gamma -, and delta -hexachlorocyclohexane (HCH). By heating the sample while cooling the fiber, the developed method not only provides better performance in terms of sensitivity, linearity and recovery but also offers shorter adsorption procedure than that of traditional headspace-solid phase microextraction (HS-SPME). The experimental conditions such as the amount of water, adsorption time and adsorption temperature were optimized. Matrix effects were investigated with different types of soils. We concluded that using the standard addition method was required for quantification purposes. The limits of detection obtained using the proposed method range from 0.01 to 0.05 ng/g, and the recoveries for CACF-SPME are in the range of 80.01% to 89.68% with relative standard deviation (RSDs) better than 8.60%. The proposed method was further applied to determine OCs in real agricultural soil. The results are in good agreement with those obtained using traditional ultrasonic extraction. The research demonstrates the suitability of the CACF-SPME for the analysis of OCs in soil.

  7. Survival analysis models and applications

    CERN Document Server

    Liu, Xian


    Survival analysis concerns sequential occurrences of events governed by probabilistic laws.  Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis.Assumes only a minimal knowledge of SAS whilst enablin

  8. IMS applications analysis

    Energy Technology Data Exchange (ETDEWEB)



    This report examines the market potential of a miniature, hand-held Ion Mobility Spectrometer. Military and civilian markets are discussed, as well as applications in a variety of diverse fields. The strengths and weaknesses of competing technologies are discussed. An extensive Ion Mobility Spectrometry (IMS) bibliography is included. The conclusions drawn from this study are: (1) There are a number of competing technologies that are capable of detecting explosives, drugs, biological, or chemical agents. The IMS system currently represents the best available compromise regarding sensitivity, specificity, and portability. (2) The military market is not as large as the commercial market, but the military services are more likely to invest R and D funds in the system. (3) Military applications should be addressed before commercial applications are addressed. (4) There is potentially a large commercial market for rugged, hand-held Ion Mobility Spectrometer systems. Commercial users typically do not invest R and D funds in this type of equipment rather, they wait for off-the-shelf availability.

  9. Harmonic analysis and applications

    CERN Document Server

    Heil, Christopher


    This self-contained volume in honor of John J. Benedetto covers a wide range of topics in harmonic analysis and related areas. These include weighted-norm inequalities, frame theory, wavelet theory, time-frequency analysis, and sampling theory. The chapters are clustered by topic to provide authoritative expositions that will be of lasting interest. The original papers collected are written by prominent researchers and professionals in the field. The book pays tribute to John J. Benedetto's achievements and expresses an appreciation for the mathematical and personal inspiration he has given to

  10. Sensitivity Analysis for Activation Problems (United States)

    Arter, Wayne; Morgan, Guy


    A study has been made as to how to develop further the techniques for sensitivity analysis used by Fispact-II. Fispact-II is a software suite for the analysis of nuclear activation and transmutation problems, developed for all nuclear applications. The software already permits sensitivity analysis to be performed by Monte Carlo sampling, and a faster uncertainty analysis is made possible by a powerful graph-based approach which generates a reduced set of nuclides on pathways leading to significant contributions to radiological quantities. The peculiar aspects of the sensitivity analysis problem for activation are the large number, typically thousands, of rate equation parameters(decay rates and reaction cross-sections) which all have some degree of associated error, and the fact that activity as a function of time varies as a sum of exponentials, so appears discontinuous as rate parameters are varied unless the sampling frequency is impractically fast. Nevertheless, Monte Carlo sampling is a generic approach and it is therefore conceivable that techniques more targeted to the activation problem might be beneficial. Moreover, recent theoretical developments have highlighted the importance of a two-stage approach to mathematically similar problems, where in the first stage, information is collected about the global behaviour of the problem, such as the identification of the rate parameters which cause the greatest variation in dose or nuclear activity, before a second stage examines a problem with its scope restricted by the information from the first. In the second stage, for example, Quasi-Monte Carlo sampling may be used in a restricted parameter space. The current work concentrates on the first stage and consists of a review of possible techniques with a detailed examination of the most promising pathways reduction approach, examined directly using Fispact-II. All the evidence obtained demonstrates the strong potential of this approach.

  11. Functional Analysis in Interdisciplinary Applications

    CERN Document Server

    Nursultanov, Erlan; Ruzhansky, Michael; Sadybekov, Makhmud


    This volume presents current research in functional analysis and its applications to a variety of problems in mathematics and mathematical physics. The book contains over forty carefully refereed contributions to the conference “Functional Analysis in Interdisciplinary Applications” (Astana, Kazakhstan, October 2017). Topics covered include the theory of functions and functional spaces; differential equations and boundary value problems; the relationship between differential equations, integral operators and spectral theory; and mathematical methods in physical sciences. Presenting a wide range of topics and results, this book will appeal to anyone working in the subject area, including researchers and students interested to learn more about different aspects and applications of functional analysis.

  12. The Factors Affecting Individuals’ Participation in Cycling, Mountaineering and Trekking Activities: An Application of Probit Analysis for Turkey Case


    Ardahan, Faik; MERT, Mehmet


    The aim of this study is to examine and explain the impacts of the independent variables as gender, marital status, income, education level, age, Life Satisfaction (LS) level, Emotional Intelligence (EQ) level and Ecological values and behavior level on participating in outdoor activities as cycling, trekking and mountaineering by using Probit Model, as Turkey case. To determine the EQ level, Ecological values and behavior level, and LS levels of participants, EQ, LS and New Ecological Paradi...

  13. Analysis of Wooden Toy Manufacturing Costs Through the Application of a Time-Driven Activity-Based Costing System


    PONGWASIT, Ramida; CHOMPU-INWAI, Rungchat


    The case study company, which manufactures wooden toys, encounters problems when fixing its product prices, since its experienced owners tend to dictate the prices of all the products, yet do not have available the appropriate product price and cost data. Currently, the company’s product costs are calculated using traditional accounting methods, but these are unable to accurately record the costs associated with the resources used and activities that occur during manufacture. Furthermore, whe...

  14. Impedance spectroscopic analysis of composite electrode from activated carbon/conductive materials/ruthenium oxide for supercapacitor applications

    Energy Technology Data Exchange (ETDEWEB)

    Taer, E.; Awitdrus,; Farma, R. [School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Department of Physics, Faculty of Mathematics and Natural Sciences, University of Riau, 28293 Pekanbaru, Riau (Indonesia); Deraman, M., E-mail:; Talib, I. A.; Ishak, M. M.; Omar, R.; Dolah, B. N. M.; Basri, N. H.; Othman, M. A. R. [School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Kanwal, S. [ICCBS, H.E.J. Research Institute of Chemistry, University of Karachi, 75270 Karachi (Pakistan)


    Activated carbon powders (ACP) were produced from the KOH treated pre-carbonized rubber wood sawdust. Different conductive materials (graphite, carbon black and carbon nanotubes (CNTs)) were added with a binder (polivinylidene fluoride (PVDF)) into ACP to improve the supercapacitive performance of the activated carbon (AC) electrodes. Symmetric supercapacitor cells, fabricated using these AC electrodes and 1 molar H{sub 2}SO{sub 4} electrolyte, were analyzed using a standard electrochemical impedance spectroscopy technique. The addition of graphite, carbon black and CNTs was found effective in reducing the cell resistance from 165 to 68, 23 and 49 Ohm respectively, and increasing the specific capacitance of the AC electrodes from 3 to 7, 17, 32 F g{sup −1} respectively. Since the addition of CNTs can produce the highest specific capacitance, CNTs were chosen as a conductive material to produce AC composite electrodes that were added with 2.5 %, 5 % and 10 % (by weight) electro-active material namely ruthenium oxide; PVDF binder and CNTs contents were kept at 5 % by weight in each AC composite produced. The highest specific capacitance of the cells obtained in this study was 86 F g{sup −1}, i.e. for the cell with the resistance of 15 Ohm and composite electrode consists of 5 % ruthenium oxide.

  15. Applications of cognitive work analysis

    CERN Document Server

    Bisantz, Ann M


    Advances in the Application of Cognitive Work Analysis, C.M. Burns and A.M. BisantzFrom Work Domains to Worker Competencies: A Five-Phase CWA for Air Traffic Control, R.M. Kilgore, O. St-Cyr, and G.A. JamiesonWork Domain Analysis using the Abstraction Hierarchy: Two Contrasting Cases, A.M. Bisantz and N. MazaevaBeyond the Design of Ecological Interfaces: Applications of Work Domain Analysis and Control Task Analysis to the Evaluation of Design Proposals, Team Design, and Training, N. NaikarControl Task Analysis: Methodologies for Eliciting and Applying Decision Ladder Models for Command and Control, T.M. Lamoureux and B. ChalmersUnderstanding Cognitive Strategies for Shared Situation Awareness Across a Distributed System: An Example of Strategies Analysis, E.M. RothA Cognitive Work Analysis of Cardiac Care Nurses Performing Teletriage, C.M. Burns and Y. EnomotoMethods for the Analysis of Social and Organizational Aspects of the Work Domain, J. Pfautz and S. PfautzTask Analysis and Cognitive Work Analysis: One...

  16. Temperature-dependent deliquescence relative humidities and water activities using humidity controlled thermogravimetric analysis with application to malonic acid. (United States)

    Beyer, Keith D; Schroeder, Jason R; Kissinger, Jared A


    We utilize a new experimental technique, humidity-controlled thermogravimetric analysis (HTGA), to determine temperature-dependent deliquescence relative humidities (DRH) and to determine the equilibrium concentration of a solution at a given temperature and relative humidity. To that end, we have investigated the malonic acid/water system determining the DRH and concentration/RH relationship in the temperature range 303-278 K. Excellent agreement is found with literature values for the DRH of malonic acid as a function of temperature and for the concentration/RH relationship at several temperatures. Thus, we extend the DRH and concentration/RH relationship to a broader temperature range and are using the HTGA experiments to investigate other organic acids.

  17. Analysis, modeling, and simulation (AMS) testbed development and evaluation to support dynamic mobility applications (DMA) and active transportation and demand management (ATDM) programs - Pasadena calibration report : draft report. (United States)


    The primary objective of this project is to develop multiple simulation testbeds/transportation models to : evaluate the impacts of DMA connected vehicle applications and the active transportation and demand : management (ATDM) strategies. The primar...

  18. Application of the dual-luciferase reporter assay to the analysis of promoter activity in Zebrafish embryos

    Directory of Open Access Journals (Sweden)

    Mulero Victoriano


    Full Text Available Abstract Background The dual-luciferase assay has been widely used in cell lines to determine rapidly but accurately the activity of a given promoter. Although this strategy has proved very useful, it does not allow the promoter and gene function to be analyzed in the context of the whole organism. Results Here, we present a rapid and sensitive assay based on the classical dual-luciferase reporter technique which can be used as a new tool to characterize the minimum promoter region of a gene as well as the in vivo response of inducible promoters to different stimuli. We illustrate the usefulness of this system for studying both constitutive (telomerase and inducible (NF-κB-dependent promoters. The flexibility of this assay is demonstrated by induction of the NF-κB-dependent promoters using simultaneous microinjection of different pathogen-associated molecular patterns as well as with the use of morpholino-gene mediated knockdown. Conclusion This assay has several advantages compared with the classical in vitro (cell lines and in vivo (transgenic mice approaches. Among others, the assay allows a rapid and quantitative measurement of the effects of particular genes or drugs in a given promoter in the context of a whole organism and it can also be used in high throughput screening experiments.

  19. Surface active monomers synthesis, properties, and application

    CERN Document Server

    Borzenkov, Mykola


    This brief includes information on the background?of and development of synthesis of various types of surface active monomers. The authors explain the importance of utilization of surface active monomers for creation of surface active polymers? and the various biomedical applications of such compounds . This brief introduces techniques for the synthesis of novel types of surface active monomers, their colloidal and polymerizable properties and application for needs of medicine and biology.

  20. Functional analysis theory and applications

    CERN Document Server

    Edwards, RE


    ""The book contains an enormous amount of information - mathematical, bibliographical and historical - interwoven with some outstanding heuristic discussions."" - Mathematical Reviews.In this massive graduate-level study, Emeritus Professor Edwards (Australian National University, Canberra) presents a balanced account of both the abstract theory and the applications of linear functional analysis. Written for readers with a basic knowledge of set theory, general topology, and vector spaces, the book includes an abundance of carefully chosen illustrative examples and excellent exercises at the

  1. Noncommutative analysis, operator theory and applications

    CERN Document Server

    Cipriani, Fabio; Colombo, Fabrizio; Guido, Daniele; Sabadini, Irene; Sauvageot, Jean-Luc


    This book illustrates several aspects of the current research activity in operator theory, operator algebras and applications in various areas of mathematics and mathematical physics. It is addressed to specialists but also to graduate students in several fields including global analysis, Schur analysis, complex analysis, C*-algebras, noncommutative geometry, operator algebras, operator theory and their applications. Contributors: F. Arici, S. Bernstein, V. Bolotnikov, J. Bourgain, P. Cerejeiras, F. Cipriani, F. Colombo, F. D'Andrea, G. Dell'Antonio, M. Elin, U. Franz, D. Guido, T. Isola, A. Kula, L.E. Labuschagne, G. Landi, W.A. Majewski, I. Sabadini, J.-L. Sauvageot, D. Shoikhet, A. Skalski, H. de Snoo, D. C. Struppa, N. Vieira, D.V. Voiculescu, and H. Woracek.

  2. Citation Analysis: Definitions and Applications

    Directory of Open Access Journals (Sweden)

    Amirhossein Abdoulmajid


    Full Text Available Citations hold a special place within scientific literature. In fact a scientific paper is deemed credible only when it cites the relevant works and papers on the subject. Citation analysis is a method based on the existing citations within scientific literature. It analyses and evaluates works by counting the number of citations used in different texts such as journals, dissertations and such. The emergence of citation indices has contributed to the remarkable growth and development of citation analysis, making it a significant research area over the past couple of decades. The present paper deals with the importance of citations and citation theories. Definitions and historical background on citation analysis as well as its various field applications are discussed.

  3. Constructivism theory analysis and application to curricula. (United States)

    Brandon, Amy F; All, Anita C


    Today's nursing programs are struggling to accommodate the changing needs of the health care environment and need to make changes in how students are taught. Using constructivism theory, whereby learning is an active process in which learners construct new ideas or concepts based upon their current or past knowledge, leaders in nursing education can make a paradigm shift toward concept-based curricula. This article presents a summary and analysis of constructivism and an innovative application of its active-learning principles to curriculum development, specifically for the education of nursing students.

  4. Network analysis applications in hydrology (United States)

    Price, Katie


    Applied network theory has seen pronounced expansion in recent years, in fields such as epidemiology, computer science, and sociology. Concurrent development of analytical methods and frameworks has increased possibilities and tools available to researchers seeking to apply network theory to a variety of problems. While water and nutrient fluxes through stream systems clearly demonstrate a directional network structure, the hydrological applications of network theory remain under­explored. This presentation covers a review of network applications in hydrology, followed by an overview of promising network analytical tools that potentially offer new insights into conceptual modeling of hydrologic systems, identifying behavioral transition zones in stream networks and thresholds of dynamical system response. Network applications were tested along an urbanization gradient in Atlanta, Georgia, USA. Peachtree Creek and Proctor Creek. Peachtree Creek contains a nest of five long­term USGS streamflow and water quality gages, allowing network application of long­term flow statistics. The watershed spans a range of suburban and heavily urbanized conditions. Summary flow statistics and water quality metrics were analyzed using a suite of network analysis techniques, to test the conceptual modeling and predictive potential of the methodologies. Storm events and low flow dynamics during Summer 2016 were analyzed using multiple network approaches, with an emphasis on tomogravity methods. Results indicate that network theory approaches offer novel perspectives for understanding long­ term and event­based hydrological data. Key future directions for network applications include 1) optimizing data collection, 2) identifying "hotspots" of contaminant and overland flow influx to stream systems, 3) defining process domains, and 4) analyzing dynamic connectivity of various system components, including groundwater­surface water interactions.

  5. Applications of Sound Spectrum Analysis (United States)

    Moran, Timothy


    The physics of sound is often studied in introductory physics class experiments involving a tube of resonating air. In typical setups, pistons control the length of a cylindrical space or a microphone is moved within a tube. While these activities are useful and can be made very quantitative, they don't directly demonstrate the sounds that are most familiar to students, such as human voices and musical instruments. Fortunately, several sound spectrum analysis programs are available that can bridge this gap.2

  6. Multiple-Active Multiple-Passive Antenna Systems and Applications

    DEFF Research Database (Denmark)

    Tsakalaki, Elpiniki


    This chapter focuses on extensions and foreseen applications of the parasitic antenna array technology. Moving beyond the single-active (single-RF) communication setup, hitherto discussed in the previous chapters, the work in this chapter extends the analysis to generalized multiple-active multiple...

  7. Analysis of Precision of Activation Analysis Method

    DEFF Research Database (Denmark)

    Heydorn, Kaj; Nørgaard, K.


    The precision of an activation-analysis method prescribes the estimation of the precision of a single analytical result. The adequacy of these estimates to account for the observed variation between duplicate results from the analysis of different samples and materials, is tested by the statistic T...

  8. Active and passive beam application design guide for global application

    CERN Document Server

    Rimmer, Julian


    The Active and Passive Beam Application Design Guide is the result of collaboration by worldwide experts to give system designers a current, authoritative guide on successfully applying active and passive beam technology. Active and Passive Beam Application Design Guide provide energy-efficient methods of cooling, heating, and ventilating indoor areas, especially spaces that require individual zone control and where internal moisture loads are moderate. The systems are simple to operate, with low maintenance requirements. This book is an essential resource for consulting engineers, architects, owners, and contractors who are involved in the design, operation, and installation of these systems. Building on REHVA’s Chilled Beam Application Guidebook, this new guide provides up-to-date tools and advice for designing, commissioning, and operating chilled-beam systems to achieve a determined indoor climate, and includes examples of active and passive beam calculations and selections. Dual units (SI and I-P) are...

  9. Active plasmonics in WDM traffic switching applications

    National Research Council Canada - National Science Library

    Papaioannou, Sotirios; Kalavrouziotis, Dimitrios; Vyrsokinos, Konstantinos; Weeber, Jean-Claude; Hassan, Karim; Markey, Laurent; Dereux, Alain; Kumar, Ashwani; Bozhevolnyi, Sergey I; Baus, Matthias; Tekin, Tolga; Apostolopoulos, Dimitrios; Avramopoulos, Hercules; Pleros, Nikos


    .... In this article, we introduce active plasmonics into Wavelength Division Multiplexed (WDM) switching applications, using the smallest TO DLSPP-based Mach-Zehnder interferometric switch reported so far and showing its successful performance in 4×10...

  10. Applications of Active Packaging in Breads

    Directory of Open Access Journals (Sweden)

    Ali Göncü


    Full Text Available Changes on consumer preferences lead to innovations and improvements in new packaging technologies. With these new developments passive packaging technologies aiming to protect food nowadays have left their place to active and intelligent packaging technologies that have other various functions beside protection of food. Active packaging is defined as an innovative packaging type and its usage increases the shelf life of food significantly. Applications of active packaging have begun to be used for packaging of breads. In this study active packaging applications in breads have been reviewed.

  11. HPLC-NNE13CNMR coupling fingerprint analysis technology and its application in a study of Syringa pubescens Turcz and its activity against hepatic fibrosis

    Directory of Open Access Journals (Sweden)

    Zhang ZX


    Full Text Available Zhixin Zhang,1 Weiping Yin,1 Pu Liu,1 Tianzeng Zhao2 1School of Chemical Engineering and Pharmaceutics, Henan University of Science and Technology, Luoyang, People’s Republic of China; 2Key Laboratory of Natural Products, Henan Academy of Sciences, Zhengzhou, People's Republic of China Abstract: This study describes the active ingredients of Syringa pubescens Turcz which has been identified as being able to protect against hepatic fibrosis. Here we report the characteristics of high performance liquid chromatography and non-nuclear overhauser effect carbon-13 nuclear magnetic resonance (HPLC-NNE13CNMR technology developed for coupling fingerprint analysis. The major contribution of this new method is the development of an efficient technology and a useful tool for analysis of a traditional Chinese herbal medicine using chromatography and spectral coupling fingerprint technology. Isolation of secoiridoid glycosides and investigation of their structure-activity relationship showed that these derivatives are the active ingredients of Syringa pubescens Turcz, and account for the activity of this plant against hepatic fibrosis. The active compounds were identified as oleuropein, 10-hydroxyoleuropein, oleoside-11-methylester, (8Z-ligstroside, and echinacoside by HPLC-NNE13CNMR coupling fingerprint analysis. A concentration-response relationship was also demonstrated for the HPLC-NNE13CNMR coupling fingerprint method. Keywords: HPLC-NNE13CNMR, coupling fingerprint, hepatic fibrosis, Syringa pubescens Turcz, analysis technology

  12. Film analysis systems and applications

    Energy Technology Data Exchange (ETDEWEB)

    Yonekura, Y.; Brill, A.B.


    The different components that can be used in modern film analysis systems are reviewed. TV camera and charge-coupled device sensors coupled to computers provide low cost systems for applications such as those described. The autoradiography (ARG) method provides an important tool for medical research and is especially useful for the development of new radiopharmaceutical compounds. Biodistribution information is needed for estimation of radiation dose, and for interpretation of the significance of observed patterns. The need for such precise information is heightened when one seeks to elucidate physiological principles/factors in normal and experimental models of disease. The poor spatial resolution achieved with current PET-imaging systems limits the information on radioreceptor mapping, neutrotransmitter, and neuroleptic drug distribution that can be achieved from patient studies. The artful use of ARG in carefully-controlled animal studies will be required to provide the additional information needed to fully understand results obtained with this new important research tool. (ERB)

  13. Mobile computer application for promoting physical activity. (United States)

    McMahon, Siobhan; Vankipuram, Mithra; Fleury, Julie


    Despite evidence that physical activity reduces the risk of falls and other causes of disability and death, the majority of older adults do not engage in physical activity on a regular basis. Mobile technology applications have emerged as potential resources for promoting physical activity behavior. This article describes features of a new application, Ready∼Steady, highlighting approaches used in its design and development, and implications for clinical practice. Iterative processes enabled the design, development, implementation, and evaluation of the application consistent with the wellness motivation theory, as well as established user-specific strategies and theoretical design principles. Implications in terms of potential benefits and constraints are discussed. Integrating technology that promotes health and wellness in the form of mobile computer applications is a promising adjunct to nursing practice. Copyright 2013, SLACK Incorporated.

  14. Active plasmonics in WDM traffic switching applications

    DEFF Research Database (Denmark)

    Papaioannou, S.; Kalavrouziotis, D.; Vyrsokinos, K.


    . The first active Dielectric-Loaded Surface Plasmon Polariton (DLSPP) thermo-optic (TO) switches with successful performance in single-channel 10 Gb/s data traffic environments have led the inroad towards bringing low-power active plasmonics in practical traffic applications. In this article, we introduce...

  15. The Supernovae Analysis Application (SNAP) (United States)

    Bayless, Amanda J.; Fryer, Chris L.; Wollaeger, Ryan; Wiggins, Brandon; Even, Wesley; de la Rosa, Janie; Roming, Peter W. A.; Frey, Lucy; Young, Patrick A.; Thorpe, Rob; Powell, Luke; Landers, Rachel; Persson, Heather D.; Hay, Rebecca


    The SuperNovae Analysis aPplication (SNAP) is a new tool for the analysis of SN observations and validation of SN models. SNAP consists of a publicly available relational database with observational light curve, theoretical light curve, and correlation table sets with statistical comparison software, and a web interface available to the community. The theoretical models are intended to span a gridded range of parameter space. The goal is to have users upload new SN models or new SN observations and run the comparison software to determine correlations via the website. There are problems looming on the horizon that SNAP is beginning to solve. For example, large surveys will discover thousands of SNe annually. Frequently, the parameter space of a new SN event is unbounded. SNAP will be a resource to constrain parameters and determine if an event needs follow-up without spending resources to create new light curve models from scratch. Second, there is no rapidly available, systematic way to determine degeneracies between parameters, or even what physics is needed to model a realistic SN. The correlations made within the SNAP system are beginning to solve these problems.

  16. Analysis, modeling, and simulation (AMS) testbed development and evaluation to support dynamic mobility applications (DMA) and active transportation and demand management (ATDM) programs - San Mateo testbed analysis plan : final report. (United States)


    The primary objective of this project is to develop multiple simulation testbeds/transportation models to : evaluate the impacts of DMA connected vehicle applications and the active and dynamic transportation : management (ATDM) strategies. The outpu...

  17. Application of activation analysis for determination of some elements in cassiterite samples; Aplicacao da analise por ativacao para a determinacao de alguns elementos em amostras de cassiterita

    Energy Technology Data Exchange (ETDEWEB)

    Armelin, Maria Jose Aguirre


    This work consists in the development of an analytical method using activation by thermal neutrons for the determination of some minor elements and traces present in cassiterite (tin ore). This method was then applied to determine these elements in samples of cassiterite from different regions of Brazil. An analysis was made of the mineralogy characteristic of cassiterite as well as of the minerals most commonly associated with it. Four main types of interference were found to occur in the analysis by activation of trace elements in samples of cassiterite. The method involves the analysis without chemical separation for the determination of some elements and the analysis with chemical separation for the determination of other elements. The steps involved in both types of analysis are described. In the analysis with chemical separation the matrix element (tin) is separated by distillation in an H{sub 2}SO{sub 4}-HBr medium, after fusion of the ore with Na{sub 2}O{sub 2}. Arsine and antimony are determined in the distilled, whereas some lanthanide elements and uranium are determined in the distillation residue by separating them as a group by precipitation with lanthanum fluoride. A discussion on the precision, accuracy and sensibility of the method is also included. (author)

  18. Handbook of Fourier analysis & its applications

    CERN Document Server

    Marks, Robert J


    Fourier analysis has many scientific applications - in physics, number theory, combinatorics, signal processing, probability theory, statistics, option pricing, cryptography, acoustics, oceanography, optics and diffraction, geometry, and other areas. In signal processing and related fields, Fourier analysis is typically thought of as decomposing a signal into its component frequencies and their amplitudes. This practical, applications-based professional handbook comprehensively covers the theory and applications of Fourier Analysis, spanning topics from engineering mathematics, signal process

  19. A concept analysis of voluntary active euthanasia. (United States)

    Guo, Fenglin


    Euthanasia has a wide range of classifications. Confusion exists in the application of specific concepts to various studies. To analyze the concept of voluntary active euthanasia using Walker and Avant's concept analysis method. A comprehensive literature review from various published literature and bibliographies. Clinical, ethical, and policy differences and similarities of euthanasia need to be debated openly, both within the medical profession and publicly. Awareness of the classifications about euthanasia may help nurses dealing with "end of life issues" properly.

  20. Active noise control technique and its application on ships

    Directory of Open Access Journals (Sweden)

    CHEN Kean


    Full Text Available Due to the rapid development during past three decades, Active Noise Control(ANC has become a highly complementary noise control approach in comparison with traditional approaches, and has formed a complete system including basic theory, investigation approach, key techniques and system implementation. Meanwhile, substantial progress has been achieved in such fields as the practical application, industrialization development and commercial popularization of ANC, and this developed technique provides a practical and feasible choice for the active control of ship noise. In this review paper, its sound field analysis, system setup and key techniques are summarized, typical examples of ANC-based engineering applications including control of cabin noise and duct noise are briefly described, and a variety of forefronts and problems associated with the applications of ANC in ship noise control, such as active sound absorption, active sound insulation and smart acoustic structure, are subsequently discussed.

  1. A systematic review and meta-analysis of applications of the Self-Report Habit Index to nutrition and physical activity behaviours. (United States)

    Gardner, Benjamin; de Bruijn, Gert-Jan; Lally, Phillippa


    Health behaviour models typically neglect habitual action. The Self-Report Habit Index (SRHI) permits synthesis of evidence of the influence of habit on behaviour. The purpose of this study is to review evidence around mean habit strength, habit-behaviour correlations, and habit x intention interactions, from applications of the SRHI to dietary, physical activity, and active travel behaviour. Electronic database searches identified 126 potentially relevant papers. Twenty-two papers (21 datasets) passed eligibility screening. Mean scores and correlations were meta-analysed using fixed, random and mixed effects, and interactions were synthesised via narrative review. Twenty-three habit-behaviour correlations and nine habit x intention interaction tests were found. Typical habit strength was located around the SRHI midpoint. Weighted habit-behaviour effects were medium-to-strong (fixed: r + = 0.44; random: r + = 0.46). Eight tests found that habit moderated the intention-behaviour relation. More comprehensive understanding of nutrition and activity behaviours will be achieved by accounting for habitual responses to contextual cues.

  2. Active glass for photonic devices photoinduced structures and their application

    CERN Document Server

    Mitsuyu, Tsuneo; Si, Jinhai; Qiu, Jianrong


    This book focuses on selected topics which are new and of fundamental importance in the application of active glasses in photonic devices Most of the chapters deal with glasses under the action of higher electromagnetic fields, such as those produced by femtosecond lasers They cover the creation and analysis of induced structures in glasses and some functional devices using active glasses This book is designed for both graduate students and researchers in the field

  3. Activities of Western Research Application Center (United States)


    Operations of the regional dissemination center for NASA technology collection and information transfer are reported. Activities include customized searches for engineering and scientific applications in industry and technology transfers to businesses engaged in manufacturing high energy physics devices, subsurface instruments, batteries, medical instrumentation, and hydraulic equipment.

  4. Activation of Tl, Pb and Bi by 10-160 MeV neutrons: possible application to the analysis of Bi

    Energy Technology Data Exchange (ETDEWEB)

    Parekh, P.P.; Finston, H.L.


    The medium energy intense neutrons (MEIN) available at the Brookhaven Chemistry Linac Irradiation Facility have an energy distribution up to approx. 160 MeV and an effective neutron flux of approx. 1.3 x 10/sup 11/ cm/sup -2/ s/sup -1/. The present work explores the feasibility of using this facility for the analysis of Tl, Pb and Bi by activation with MEIN. The most sensitive reactions, from a practical standpoint, were found to be Tl (n, xn) /sup 200/Tl (x = 4, 6), Pb (n, xn) /sup 204//sup m/Pb (x = 0, 3, 4, 5) and /sup 209/Bi (n, 6n) /sup 204/Bi. The absolute sensitivities attainable with these reactions are 0.1, 0.05 and 0.08 of Tl, Pb and Bi respectively, for 1 h irradiation at 1.3 x 10/sup 11/ n cm/sup -2/ s/sup -1/ with samples counted 2 h after the end of irradiation. The advantages of the method over thermal neutron activation analysis are that all three elements can be assayed at the sub-microgram concentration levels by ..gamma..-spectrometry with the help of a simple radiochemical purificaton and the analytical results can be verified by cross checking via the multiple (n, xn) reaction products. However, interference from Bi in the determination of Pb and from Pb and Bi in the determination of Tl limits its usefulness to the analysis of Bi.

  5. Studies on application of neutron activation analysis -Applied research on air pollution monitoring and development of analytical method of environmental samples

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Chung, Young Ju; Jeong, Eui Sik; Lee, Sang Mi; Kang, Sang Hun; Cho, Seung Yeon; Kwon, Young Sik; Chung, Sang Wuk; Lee, Kyu Sung; Chun, Ki Hong; Kim, Nak Bae; Lee, Kil Yong; Yoon, Yoon Yeol; Chun, Sang Ki


    This research report is written for results of applied research on air pollution monitoring using instrumental neutron activation analysis. For identification and standardization of analytical method, 24 environmental samples are analyzed quantitatively, and accuracy and precision of this method are measured. Using airborne particulate matter and biomonitor chosen as environmental indicators, trace elemental concentrations of sample collected at urban and rural site monthly are determined ant then the calculation of statistics and the factor analysis are carried out for investigation of emission source. Facilities for NAA are installed in a new HANARO reactor, functional test is performed for routine operation. In addition, unified software code for NAA is developed to improve accuracy, precision and abilities of analytical processes. (author). 103 refs., 61 tabs., 19 figs.

  6. The application of digital image analysis for blood typing: the comparison of anti-A and anti-B monoclonal antibodies activity with standard hemagglutinating sera (United States)

    Medvedeva, Maria F.; Doubrovski, Valery A.


    The resolution of the acousto-optical method for blood typing was estimated experimentally by means of two types of reagents: monoclonal antibodies and standard hemagglutinating sera. The peculiarity of this work is the application of digital photo images processing by pixel analysis previously proposed by the authors. The influence of the concentrations of reagents, of blood sample, which is to be tested, as well as of the duration of the ultrasonic action on the biological object upon the resolution of acousto-optical method were investigated. The optimal experimental conditions to obtain maximum of the resolution of the acousto-optical method were found, it creates the prerequisites for a reliable blood typing. The present paper is a further step in the development of acousto-optical method for determining human blood groups.

  7. Standardized application of yeast bioluminescent reporters as endocrine disruptor screen for comparative analysis of wastewater effluents from membrane bioreactor and traditional activated sludge. (United States)

    Wang, Jun; Eldridge, Melanie; Menn, Fu-min; Dykes, Todd; Sayler, Gary


    A standardized protocol is demonstrated for bioluminescent strains Saccharomyces cerevisiae BLYES, BLYAS and BLYR as high-throughput screening tools to monitor the estrogenic, androgenic and toxic potencies in wastewater. The sensitivity and reproducibility of the assay in wastewater monitoring was evaluated for 7 day semi-continuous batch reactor using activated sludge with hormones spiked raw sewage. Yeast bioluminescent assay successfully captured the rapid removal of estrogenic and androgenic activities in the bioreactors, and demonstrated rapid response (≤4 h) with good reproducibility. This standardized protocol was then applied in a 12 months monitoring of the effluent of a WWTP located at Powell, TN, USA featuring parallel-operated full-scale membrane bioreactor (MBR) and traditional activated sludge (TAS) treatment. Monitoring results showed that estrogenic activity was persistent in all TAS and most MBR effluent samples, while residual androgenic activity was non-detectable throughout the monitored period. The estrogenic equivalents (EEQ) in TAS effluent ranged from 21.61 ng/L to 0.04 pg/L and averaged 3.25 ng/L. The EEQ in MBR effluent ranged from 2.88 ng/L to 0.0134 pg/L and averaged ~10 fold less (0.32 ng/L) than TAS. Despite the large temporal variation, MBR effluent EEQ was consistently lower than TAS on any given sampling date. Most MBR effluent samples also exhibited less cytotoxicity than TAS. Further analysis did not demonstrate significant correlation between effluent EEQ level and WWTP operational parameters including MLSS, SRT, HRT and BOD.

  8. Techniques and Applications of Urban Data Analysis

    KAUST Repository

    AlHalawani, Sawsan N.


    Digitization and characterization of urban spaces are essential components as we move to an ever-growing ’always connected’ world. Accurate analysis of such digital urban spaces has become more important as we continue to get spatial and social context-aware feedback and recommendations in our daily activities. Modeling and reconstruction of urban environments have thus gained unprecedented importance in the last few years. Such analysis typically spans multiple disciplines, such as computer graphics, and computer vision as well as architecture, geoscience, and remote sensing. Reconstructing an urban environment usually requires an entire pipeline consisting of different tasks. In such a pipeline, data analysis plays a strong role in acquiring meaningful insights from the raw data. This dissertation primarily focuses on the analysis of various forms of urban data and proposes a set of techniques to extract useful information, which is then used for different applications. The first part of this dissertation presents a semi-automatic framework to analyze facade images to recover individual windows along with their functional configurations such as open or (partially) closed states. The main advantage of recovering both the repetition patterns of windows and their individual deformation parameters is to produce a factored facade representation. Such a factored representation enables a range of applications including interactive facade images, improved multi-view stereo reconstruction, facade-level change detection, and novel image editing possibilities. The second part of this dissertation demonstrates the importance of a layout configuration on its performance. As a specific application scenario, I investigate the interior layout of warehouses wherein the goal is to assign items to their storage locations while reducing flow congestion and enhancing the speed of order picking processes. The third part of the dissertation proposes a method to classify cities

  9. The Soil Moisture Active Passive (SMAP) Applications Activity (United States)

    Brown, Molly E.; Moran, Susan; Escobar, Vanessa; Entekhabi, Dara; O'Neill, Peggy; Njoku, Eni


    The Soil Moisture Active Passive (SMAP) mission is one of the first-tier satellite missions recommended by the U.S. National Research Council Committee on Earth Science and Applications from Space. The SMAP mission 1 is under development by NASA and is scheduled for launch late in 2014. The SMAP measurements will allow global and high-resolution mapping of soil moisture and its freeze/thaw state at resolutions from 3-40 km. These measurements will have high value for a wide range of environmental applications that underpin many weather-related decisions including drought and flood guidance, agricultural productivity estimation, weather forecasting, climate predictions, and human health risk. In 2007, NASA was tasked by The National Academies to ensure that emerging scientific knowledge is actively applied to obtain societal benefits by broadening community participation and improving means for use of information. SMAP is one of the first missions to come out of this new charge, and its Applications Plan forms the basis for ensuring its commitment to its users. The purpose of this paper is to outline the methods and approaches of the SMAP applications activity, which is designed to increase and sustain the interaction between users and scientists involved in mission development.

  10. Application of Neutron Activation Analysis for Determination of As, Cr, Hg, and Se in Mosses in the Metropolitan Area of the Valley of Toluca, Mexico

    Directory of Open Access Journals (Sweden)

    R. Mejía-Cuero


    Full Text Available This research presents a study of environmental monitoring at different sampling sites from the Metropolitan Area of the Valley of Toluca (MAVT, Mexico, using mosses (Leskea angustata (Tayl. and Fabronia ciliaris (Brid. and soil samples. The epiphytic mosses and soils were sampled in two campaigns within two periods of the year, a rainy and dry-cold season. The selected sampling sites included urban regions (UR, transitional regions (TR, and protected natural areas (PA. The samples were analyzed by the Instrumental Neutron Activation Analysis (INAA to determine As, Cr, Hg, and Se principally. However, due to the versatility of the analytic technique used, other elements including Cs, Co, Sc, Sb, Rb, Ce, La, Eu, and Yb were also detected. Statistical analysis (As, Cr, Hg, and Se was carried out with principal components and cluster analysis methods; this revealed that a good correlation exists between metal content in mosses and the degree of pollution in the areas sampled. The obtained results in mosses showed that the concentrations of As, Cr, Co, Cs, Rb, Ce, La, and Yb increased with respect to the concentrations obtained during the first sampling, whereas Se, Sc, Sb and Eu, concentrations were decreased. For As and Hg, the concentrations were similar in both sampling periods. The soil samples present the most significant concentration.

  11. Patterns of Treatment Switching in Multiple Sclerosis Therapies in US Patients Active on Social Media: Application of Social Media Content Analysis to Health Outcomes Research. (United States)

    Risson, Valéry; Saini, Deepanshu; Bonzani, Ian; Huisman, Alice; Olson, Melvin


    Social media analysis has rarely been applied to the study of specific questions in outcomes research. The aim was to test the applicability of social media analysis to outcomes research using automated listening combined with filtering and analysis of data by specialists. After validation, the process was applied to the study of patterns of treatment switching in multiple sclerosis (MS). A comprehensive listening and analysis process was developed that blended automated listening with filtering and analysis of data by life sciences-qualified analysts and physicians. The population was patients with MS from the United States. Data sources were Facebook, Twitter, blogs, and online forums. Sources were searched for mention of specific oral, injectable, and intravenous (IV) infusion treatments. The representativeness of the social media population was validated by comparison with community survey data and with data from three large US administrative claims databases: MarketScan, PharMetrics Plus, and Department of Defense. A total of 10,260 data points were sampled for manual review: 3025 from Twitter, 3771 from Facebook, 2773 from Internet forums, and 691 from blogs. The demographics of the social media population were similar to those reported from community surveys and claims databases. Mean age was 39 (SD 11) years and 14.56% (326/2239) of the population was older than 50 years. Women, patients aged 30 to 49 years, and those diagnosed for more than 10 years were represented by more data points than other patients were. Women also accounted for a large majority (82.6%, 819/991) of reported switches. Two-fifths of switching patients had lived with their disease for more than 10 years since diagnosis. Most reported switches (55.05%, 927/1684) were from injectable to oral drugs with switches from IV therapies to orals the second largest switch (15.38%, 259/1684). Switches to oral drugs accounted for more than 80% (927/1114) of the switches away from injectable

  12. Development of educational program for neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong Sam; Moon, Jong Hwa; Kim, Sun Ha; Ryel, Sung; Kang, Young Hwan; Lee, Kil Yong; Yeon, Yeon Yel; Cho, Seung Yeon


    This technical report is developed to apply an educational and training program for graduate student and analyst utilizing neutron activation analysis. The contents of guide book consists of five parts as follows; introduction, gamma-ray spectrometry and measurement statistics, its applications, to understand of comprehensive methodology and to utilize a relevant knowledge and information on neutron activation analysis.

  13. Analysis from concepts to applications

    CERN Document Server

    Penot, Jean-Paul


    This textbook covers the main results and methods of real analysis in a single volume. Taking a progressive approach to equations and transformations, this book starts with the very foundations of real analysis (set theory, order, convergence, and measure theory) before presenting powerful results that can be applied to concrete problems. In addition to classical results of functional analysis, differential calculus and integration, Analysis discusses topics such as convex analysis, dissipative operators and semigroups which are often absent from classical treatises. Acknowledging that analysis has significantly contributed to the understanding and development of the present world, the book further elaborates on techniques which pervade modern civilization, including wavelets in information theory, the Radon transform in medical imaging and partial differential equations in various mechanical and physical phenomena. Advanced undergraduate and graduate students, engineers as well as practitioners wishing to fa...

  14. Designing Interactive Applications to Support Novel Activities

    Directory of Open Access Journals (Sweden)

    Hyowon Lee


    Full Text Available R&D in media-related technologies including multimedia, information retrieval, computer vision, and the semantic web is experimenting on a variety of computational tools that, if sufficiently matured, could support many novel activities that are not practiced today. Interactive technology demonstration systems produced typically at the end of their projects show great potential for taking advantage of technological possibilities. These demo systems or “demonstrators” are, even if crude or farfetched, a significant manifestation of the technologists’ visions in transforming emerging technologies into novel usage scenarios and applications. In this paper, we reflect on design processes and crucial design decisions made while designing some successful, web-based interactive demonstrators developed by the authors. We identify methodological issues in applying today’s requirement-driven usability engineering method to designing this type of novel applications and solicit a clearer distinction between designing mainstream applications and designing novel applications. More solution-oriented approaches leveraging design thinking are required, and more pragmatic evaluation criteria is needed that assess the role of the system in exploiting the technological possibilities to provoke further brainstorming and discussion. Such an approach will support a more efficient channelling of the technology-to-application transformation which are becoming increasingly crucial in today’s context of rich technological possibilities.

  15. The application of neutron activation analysis, scanning electron microscope, and radiographic imaging for the characterization of electrochemically deposited layers of lanthanide and actinide elements (United States)

    Liebe, D.; Eberhardt, K.; Hartmann, W.; Häger, T.; Hübner, A.; Kratz, J. V.; Kindler, B.; Lommel, B.; Thörle, P.; Schädel, M.; Steiner, J.


    Lanthanide and actinide targets are prepared at the University of Mainz by molecular plating, an electrochemical deposition from an organic solvent, for heavy-ion reaction studies at GSI. To acquire information about deposition yield, target thickness, and target homogeneity, the following analysis methods are applied. With neutron activation analysis (NAA) the deposition yield and the average thickness of the deposited material is determined. We report on the analytical procedure of NAA performed subsequent to the molecular plating process. Scanning electron microscope (SEM) is used to determine the morphology of the target surfaces. In combination with energy dispersive X-ray spectrometer (EDS), we also could obtain qualitative information about the chemical form of the deposited material. So far, gadolinium, samarium, holmium, and uranium targets have been investigated with SEM/EDS. With radiographic imaging (RI), targets of uranium prepared by molecular plating and by vacuum vaporization are investigated. This method is suitable to obtain information about the spatial distribution, the homogeneity, and the thickness of the target layer deposition.

  16. Activity Recognition Using Complex Network Analysis. (United States)

    Jalloul, Nahed; Poree, Fabienne; Viardot, Geoffrey; L'Hostis, Phillipe; Carrault, Guy


    In this paper, we perform complex network analysis on a connectivity dataset retrieved from a monitoring system in order to classify simple daily activities. The monitoring system is composed of a set of wearable sensing modules positioned on the subject's body and the connectivity data consists of the correlation between each pair of modules. A number of network measures are then computed followed by the application of statistical significance and feature selection methods. These methods were implemented for the purpose of reducing the total number of modules in the monitoring system required to provide accurate activity classification. The obtained results show that an overall accuracy of 84.6% for activity classification is achieved, using a Random Forest (RF) classifier, and when considering a monitoring system composed of only two modules positioned at the Neck and Thigh of the subject's body.

  17. Real analysis modern techniques and their applications

    CERN Document Server

    Folland, Gerald B


    An in-depth look at real analysis and its applications-now expanded and revised.This new edition of the widely used analysis book continues to cover real analysis in greater detail and at a more advanced level than most books on the subject. Encompassing several subjects that underlie much of modern analysis, the book focuses on measure and integration theory, point set topology, and the basics of functional analysis. It illustrates the use of the general theories and introduces readers to other branches of analysis such as Fourier analysis, distribution theory, and probability theory.This edi

  18. Progress in spatial analysis methods and applications

    CERN Document Server

    Páez, Antonio; Buliung, Ron N; Dall'erba, Sandy


    This book brings together developments in spatial analysis techniques, including spatial statistics, econometrics, and spatial visualization, and applications to fields such as regional studies, transportation and land use, population and health.

  19. Ion beam analysis fundamentals and applications

    CERN Document Server

    Nastasi, Michael; Wang, Yongqiang


    Ion Beam Analysis: Fundamentals and Applications explains the basic characteristics of ion beams as applied to the analysis of materials, as well as ion beam analysis (IBA) of art/archaeological objects. It focuses on the fundamentals and applications of ion beam methods of materials characterization.The book explains how ions interact with solids and describes what information can be gained. It starts by covering the fundamentals of ion beam analysis, including kinematics, ion stopping, Rutherford backscattering, channeling, elastic recoil detection, particle induced x-ray emission, and nucle

  20. TV content analysis techniques and applications

    CERN Document Server

    Kompatsiaris, Yiannis


    The rapid advancement of digital multimedia technologies has not only revolutionized the production and distribution of audiovisual content, but also created the need to efficiently analyze TV programs to enable applications for content managers and consumers. Leaving no stone unturned, TV Content Analysis: Techniques and Applications provides a detailed exploration of TV program analysis techniques. Leading researchers and academics from around the world supply scientifically sound treatment of recent developments across the related subject areas--including systems, architectures, algorithms,

  1. Analysis of mixed data methods & applications

    CERN Document Server

    de Leon, Alexander R


    A comprehensive source on mixed data analysis, Analysis of Mixed Data: Methods & Applications summarizes the fundamental developments in the field. Case studies are used extensively throughout the book to illustrate interesting applications from economics, medicine and health, marketing, and genetics. Carefully edited for smooth readability and seamless transitions between chaptersAll chapters follow a common structure, with an introduction and a concluding summary, and include illustrative examples from real-life case studies in developmental toxicolog

  2. Applications of Sound Spectrum Analysis (United States)

    Moran, Timothy


    The physics of sound is often studied in introductory physics class experiments involving a tube of resonating air. In typical setups, pistons control the length of a cylindrical space or a microphone is moved within a tube. While these activities are useful and can be made very quantitative, they don't directly demonstrate the sounds that are…

  3. Application of inertial sensors for motion analysis

    Directory of Open Access Journals (Sweden)

    Ferenc Soha


    Full Text Available This paper presents our results on the application of various inertial sensors for motion analysis. After the introduction of different sensor types (accelerometer, gyroscope, magnetic field sensor, we discuss the possible data collection and transfer techniques using embedded signal processing and wireless data communication methods [1,2]. Special consideration is given to the interpretation of accelerometer readings, which contains both the static and dynamic components, and is affected by the orientation and rotation of the sensor. We will demonstrate the possibility to decompose these components for quasiperiodic motions. Finally we will demonstrate the application of commercially available devices (Wii sensor, Kinect sensor, mobile phone for motion analysis applications.

  4. Mathematical analysis, approximation theory and their applications

    CERN Document Server

    Gupta, Vijay


    Designed for graduate students, researchers, and engineers in mathematics, optimization, and economics, this self-contained volume presents theory, methods, and applications in mathematical analysis and approximation theory. Specific topics include: approximation of functions by linear positive operators with applications to computer aided geometric design, numerical analysis, optimization theory, and solutions of differential equations. Recent and significant developments in approximation theory, special functions and q-calculus along with their applications to mathematics, engineering, and social sciences are discussed and analyzed. Each chapter enriches the understanding of current research problems and theories in pure and applied research.

  5. Failure environment analysis tool applications (United States)

    Pack, Ginger L.; Wadsworth, David B.


    Understanding risks and avoiding failure are daily concerns for the women and men of NASA. Although NASA's mission propels us to push the limits of technology, and though the risks are considerable, the NASA community has instilled within, the determination to preserve the integrity of the systems upon which our mission and, our employees lives and well-being depend. One of the ways this is being done is by expanding and improving the tools used to perform risk assessment. The Failure Environment Analysis Tool (FEAT) was developed to help engineers and analysts more thoroughly and reliably conduct risk assessment and failure analysis. FEAT accomplishes this by providing answers to questions regarding what might have caused a particular failure; or, conversely, what effect the occurrence of a failure might have on an entire system. Additionally, FEAT can determine what common causes could have resulted in other combinations of failures. FEAT will even help determine the vulnerability of a system to failures, in light of reduced capability. FEAT also is useful in training personnel who must develop an understanding of particular systems. FEAT facilitates training on system behavior, by providing an automated environment in which to conduct 'what-if' evaluation. These types of analyses make FEAT a valuable tool for engineers and operations personnel in the design, analysis, and operation of NASA space systems.

  6. A Paradigmatic Analysis of Digital Application Marketplaces

    DEFF Research Database (Denmark)

    Ghazawneh, Ahmad; Henfridsson, Ola


    This paper offers a paradigmatic analysis of digital application marketplaces for advancing information systems research on digital platforms and ecosystems. We refer to the notion of digital application marketplace, colloquially called ‘appstores,’ as a platform component that offers a venue...... marketplaces, platforms, and platform ecosystems. To this end, we generate a typology that distinguishes four kinds of digital application marketplaces: closed, censored, focused, and open marketplaces. The paper also offers implications for actors wishing to make informed decisions about their relationship...... to a particular digital application marketplace....

  7. Vibrational optical activity principles and applications

    CERN Document Server

    Nafie, Laurence A


    This unique book stands as the only comprehensive introduction to vibrational optical activity (VOA) and is the first single book that serves as a complete reference for this relatively new, but increasingly important area of molecular spectroscopy. Key features:A single-source reference on this topic that introduces, describes the background and foundation of this area of spectroscopy.Serves as a guide on how to use it to carry out applications with relevant problem solving.Depth and breadth of the subject is presented in a logical, complete and progressive fashion. A

  8. Active chainmail fabrics for soft robotic applications (United States)

    Ransley, Mark; Smitham, Peter; Miodownik, Mark


    This paper introduces a novel type of smart textile with electronically responsive flexibility. The chainmail inspired fabric is modelled parametrically and simulated via a rigid body physics framework with an embedded model of temperature controlled actuation. Our model assumes that individual fabric linkages are rigid and deform only through their own actuation, thereby decoupling flexibility from stiffness. A physical prototype of the active fabric is constructed and it is shown that flexibility can be significantly controlled through actuator strains of ≤10%. Applications of these materials to soft-robotics such as dynamically reconfigurable orthoses and splints are discussed.

  9. Design and Analysis of Web Application Frameworks

    DEFF Research Database (Denmark)

    Schwarz, Mathias Romme

    some of the common errors through an API that is designed to be safe by default. Second, we present a novel technique for checking HTML validity for output that is generated by web applications. Through string analysis, we approximate the output of web applications as context-free grammars. We model...... the HTML validation algorithm and the DTD language, and we generalize the validation algorithm to work for context-free grammars. Third, we present a novel technique for identifying client-state manipulation vulnerabilities. The technique uses a combination of output analysis and information ow analysis......Numerous web application frameworks have been developed in recent years. These frameworks enable programmers to reuse common components and to avoid typical pitfalls in web application development. Although such frameworks help the programmer to avoid many common errors, we nd...

  10. Analysis and Application of Microgrids (United States)

    Yue, Lu

    New trends of generating electricity locally and utilizing non-conventional or renewable energy sources have attracted increasing interests due to the gradual depletion of conventional fossil fuel energy sources. The new type of power generation is called Distributed Generation (DG) and the energy sources utilized by Distributed Generation are termed Distributed Energy Sources (DERs). With DGs embedded in the distribution networks, they evolve from passive distribution networks to active distribution networks enabling bidirectional power flows in the networks. Further incorporating flexible and intelligent controllers and employing future technologies, active distribution networks will turn to a Microgrid. A Microgrid is a small-scale, low voltage Combined with Heat and Power (CHP) supply network designed to supply electrical and heat loads for a small community. To further implement Microgrids, a sophisticated Microgrid Management System must be integrated. However, due to the fact that a Microgrid has multiple DERs integrated and is likely to be deregulated, the ability to perform real-time OPF and economic dispatch with fast speed advanced communication network is necessary. In this thesis, first, problems such as, power system modelling, power flow solving and power system optimization, are studied. Then, Distributed Generation and Microgrid are studied and reviewed, including a comprehensive review over current distributed generation technologies and Microgrid Management Systems, etc. Finally, a computer-based AC optimization method which minimizes the total transmission loss and generation cost of a Microgrid is proposed and a wireless communication scheme based on synchronized Code Division Multiple Access (sCDMA) is proposed. The algorithm is tested with a 6-bus power system and a 9-bus power system.

  11. Functional analysis, spectral theory, and applications

    CERN Document Server

    Einsiedler, Manfred


    This textbook provides a careful treatment of functional analysis and some of its applications in analysis, number theory, and ergodic theory. In addition to discussing core material in functional analysis, the authors cover more recent and advanced topics, including Weyl’s law for eigenfunctions of the Laplace operator, amenability and property (T), the measurable functional calculus, spectral theory for unbounded operators, and an account of Tao’s approach to the prime number theorem using Banach algebras. The book further contains numerous examples and exercises, making it suitable for both lecture courses and self-study. Functional Analysis, Spectral Theory, and Applications is aimed at postgraduate and advanced undergraduate students with some background in analysis and algebra, but will also appeal to everyone with an interest in seeing how functional analysis can be applied to other parts of mathematics.

  12. NASA Soil Moisture Active Passive (SMAP) Applications (United States)

    Orr, Barron; Moran, M. Susan; Escobar, Vanessa; Brown, Molly E.


    The launch of the NASA Soil Moisture Active Passive (SMAP) mission in 2014 will provide global soil moisture and freeze-thaw measurements at moderate resolution (9 km) with latency as short as 24 hours. The resolution, latency and global coverage of SMAP products will enable new applications in the fields of weather, climate, drought, flood, agricultural production, human health and national security. To prepare for launch, the SMAP mission has engaged more than 25 Early Adopters. Early Adopters are users who have a need for SMAP-like soil moisture or freeze-thaw data, and who agreed to apply their own resources to demonstrate the utility of SMAP data for their particular system or model. In turn, the SMAP mission agreed to provide Early Adopters with simulated SMAP data products and pre-launch calibration and validation data from SMAP field campaigns, modeling, and synergistic studies. The applied research underway by Early Adopters has provided fundamental knowledge of how SMAP data products can be scaled and integrated into users' policy, business and management activities to improve decision-making efforts. This presentation will cover SMAP applications including weather and climate forecasting, vehicle mobility estimation, quantification of greenhouse gas emissions, management of urban potable water supply, and prediction of crop yield. The presentation will end with a discussion of potential international applications with focus on the ESA/CEOS TIGER Initiative entitled "looking for water in Africa", the United Nations (UN) Convention to Combat Desertification (UNCCD) which carries a specific mandate focused on Africa, the UN Framework Convention on Climate Change (UNFCCC) which lists soil moisture as an Essential Climate Variable (ECV), and the UN Food and Agriculture Organization (FAO) which reported a food and nutrition crisis in the Sahel.

  13. A5: Automated Analysis of Adversarial Android Applications (United States)


    malicious (or not). The system instruments Linux features and scans applications for the use of potentially dangerous criteria. Like Andrubis, this system...collect network activity during dynamic analysis. For physical instances, A5 makes use of commodity network capture tools use on a shared WIFI access

  14. Applications of cooperative games to business activities

    Directory of Open Access Journals (Sweden)

    Rafel Amer


    Full Text Available We show several applications of the cooperative game theory and the Shapley value to business activities. Among them we emphasize on the sharing of costs or profits. In the theoretical part, the axiomatic setting proposed by Shapley is described and the properties of the value are studied. It is also shown the usefulness of simple games to describe and analyze collective decision systems ruled by voting. Many of these systems admit a representation as weighted majority games, a class of simple games. One of the most interesting problems in this case is to define a measure of the power distribution among the agents involved in the system. This problem receives a nice solution by means of the Shapley–Shubik index of power, which is the restriction of the Shapley value to simple games.

  15. Biologically active extracts with kidney affections applications (United States)

    Pascu (Neagu), Mihaela; Pascu, Daniela-Elena; Cozea, Andreea; Bunaciu, Andrei A.; Miron, Alexandra Raluca; Nechifor, Cristina Aurelia


    This paper is aimed to select plant materials rich in bioflavonoid compounds, made from herbs known for their application performances in the prevention and therapy of renal diseases, namely kidney stones and urinary infections (renal lithiasis, nephritis, urethritis, cystitis, etc.). This paper presents a comparative study of the medicinal plant extracts composition belonging to Ericaceae-Cranberry (fruit and leaves) - Vaccinium vitis-idaea L. and Bilberry (fruit) - Vaccinium myrtillus L. Concentrated extracts obtained from medicinal plants used in this work were analyzed from structural, morphological and compositional points of view using different techniques: chromatographic methods (HPLC), scanning electronic microscopy, infrared, and UV spectrophotometry, also by using kinetic model. Liquid chromatography was able to identify the specific compounds of the Ericaceae family, present in all three extracts, arbutosid, as well as specific components of each species, mostly from the class of polyphenols. The identification and quantitative determination of the active ingredients from these extracts can give information related to their therapeutic effects.

  16. Method for Systematic Assessment of Chemical Changes in Molecular Scaffolds with Conserved Topology and Application to the Analysis of Scaffold-Activity Relationships. (United States)

    Hu, Ye; Zhang, Bijun; Bajorath, Jürgen


    Sets of scaffolds with conserved molecular topology are abundant among drugs and bioactive compounds. Core structure topology is one of the determinants of biological activity. Heteroatom replacements and/or bond order variation render topologically equivalent scaffolds chemically distinct and also contribute to differences in the biological activity of compounds containing these scaffolds. Relationships between core structure topology, chemical modifications, and observed activity profiles are difficult to analyze. A computational method is introduced to consistently assess chemical transformations that distinguish scaffolds with conserved topology. The methodology is applied to quantify chemical differences in conserved topological environments and systematically relate chemical changes in topologically equivalent scaffolds to associated activity profiles. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Web Applications of Bibliometrics and Link Analysis

    Directory of Open Access Journals (Sweden)

    Faribourz Droudi


    Full Text Available The present study aims to introduce and analyze bibliometric application within Web and also to expounds on the status of link analysis in order to point out its application with respect to the existing web-based information sources. Findings indicate that bibliometrics could have required application in the area of digital resources available through Net. Link analysis is a process by which one could make statistical analysis of correlation between hyperlinks and therefore understand the accuracy, veracity and efficacy of citations within a digital document. Link analysis, in effect, is counted as a part of information ranking algorithm within the web environment. The number, linkage and quality of given links to a website are of utmost importance for ranking/status in the Web. The tools applied in this topic include, page ranking strategy, link analysis algorithm, latent semantic indexing and the classical input-output model. The present study analyzes Big Web and Small Web link analysis and explains the means for utilizing web charts in order to better understand the link analysis process.

  18. Voxel-Based LIDAR Analysis and Applications (United States)

    Hagstrom, Shea T.

    One of the greatest recent changes in the field of remote sensing is the addition of high-quality Light Detection and Ranging (LIDAR) instruments. In particular, the past few decades have been greatly beneficial to these systems because of increases in data collection speed and accuracy, as well as a reduction in the costs of components. These improvements allow modern airborne instruments to resolve sub-meter details, making them ideal for a wide variety of applications. Because LIDAR uses active illumination to capture 3D information, its output is fundamentally different from other modalities. Despite this difference, LIDAR datasets are often processed using methods appropriate for 2D images and that do not take advantage of its primary virtue of 3-dimensional data. It is this problem we explore by using volumetric voxel modeling. Voxel-based analysis has been used in many applications, especially medical imaging, but rarely in traditional remote sensing. In part this is because the memory requirements are substantial when handling large areas, but with modern computing and storage this is no longer a significant impediment. Our reason for using voxels to model scenes from LIDAR data is that there are several advantages over standard triangle-based models, including better handling of overlapping surfaces and complex shapes. We show how incorporating system position information from early in the LIDAR point cloud generation process allows radiometrically-correct transmission and other novel voxel properties to be recovered. This voxelization technique is validated on simulated data using the Digital Imaging and Remote Sensing Image Generation (DIRSIG) software, a first-principles based ray-tracer developed at the Rochester Institute of Technology. Voxel-based modeling of LIDAR can be useful on its own, but we believe its primary advantage is when applied to problems where simpler surface-based 3D models conflict with the requirement of realistic geometry. To

  19. Analysis of Maths Learning Activities Developed By Pre-service Teachers in Terms of the Components of Content, Purpose, Application Methods

    Directory of Open Access Journals (Sweden)

    Çağla Toprak


    Full Text Available Today- when the influence of the alteration movement done in order to keep up with the age of the educational system is still continuing- the importance of teachers in students’ learning and achieving what is expected from the education system has been stated by the studies conducted (Hazır & Bıkmaz, 2006. Teachers own a critical role in the stage of both preparing teaching materials and using them (Stein & Smith, 1998b; Swan, 2007. When the existing curriculums –in particular, maths and geometry cirriculums- are analyzed, it can be observed that activities are the most significant teaching materials (Bozkurt, 2012. In fact, it is possible to characterize the existing curriculums as activity-based ones (Report of Workshop Examining Content of Primary School Curriculums According to Branches, 2010; Epö, 2005. Therefore, what sort of learning activities there are, what qualities they need to have, how to design and apply them are topics that must be elaborated (Uğurel et al., 2010.  At this point, our study to increase the skills of pre-service teachers during the process of developing activities was conducted with 27 pre-service teachers -19 girls 8 boys- studying in the 4th year in Mathematics Education Department at a state university in the Aegean Region. The activity designs the pre-service teachers developed considering the patterns given after a series of practice were analyzed in documents in terms of the aim of design and the form of practice. As a result of the studies, it is observed that pre-service teachers deal with the topics from the maths curriculum and these topics are of different grade levels. The result of the examination named as target component suggests that activities developed aim firstly at providing learning and this is followed by reinforcing the concepts already learned. It is stated that pre-service teachers prefer mostly small group (cooperative studies in the activities they develop.Key Words:

  20. Development of HANARO Activation Analysis System and Utilization Technology

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Y. S.; Moon, J. H.; Cho, H. J. (and others)


    1. Establishment of evaluation system using a data for a neutron activation analysis : Improvement of NAA measurement system and its identification, Development of combined data evaluation code of NAA/PGAA, International technical cooperation project 2. Development of technique for a industrial application of high precision gamma nuclide spectroscopic analysis : Analytical quality control, Development of industrial application techniques and its identification 3. Industrial application research for a prompt gamma-ray activation analysis : Improvement of Compton suppression counting system (PGAA), Development of applied technology using a PGAA system 4. Establishment of NAA user supporting system and KOLAS management : Development and validation of KOLAS/ISO accreditation testing and identification method, Cooperation researches for a industrial application, Establishment of integrated user analytical supporting system, Accomplishment of sample irradiation facility.

  1. Nonlinear principal component analysis and its applications

    CERN Document Server

    Mori, Yuichi; Makino, Naomichi


    This book expounds the principle and related applications of nonlinear principal component analysis (PCA), which is useful method to analyze mixed measurement levels data. In the part dealing with the principle, after a brief introduction of ordinary PCA, a PCA for categorical data (nominal and ordinal) is introduced as nonlinear PCA, in which an optimal scaling technique is used to quantify the categorical variables. The alternating least squares (ALS) is the main algorithm in the method. Multiple correspondence analysis (MCA), a special case of nonlinear PCA, is also introduced. All formulations in these methods are integrated in the same manner as matrix operations. Because any measurement levels data can be treated consistently as numerical data and ALS is a very powerful tool for estimations, the methods can be utilized in a variety of fields such as biometrics, econometrics, psychometrics, and sociology. In the applications part of the book, four applications are introduced: variable selection for mixed...

  2. Abel integral equations analysis and applications

    CERN Document Server

    Gorenflo, Rudolf


    In many fields of application of mathematics, progress is crucially dependent on the good flow of information between (i) theoretical mathematicians looking for applications, (ii) mathematicians working in applications in need of theory, and (iii) scientists and engineers applying mathematical models and methods. The intention of this book is to stimulate this flow of information. In the first three chapters (accessible to third year students of mathematics and physics and to mathematically interested engineers) applications of Abel integral equations are surveyed broadly including determination of potentials, stereology, seismic travel times, spectroscopy, optical fibres. In subsequent chapters (requiring some background in functional analysis) mapping properties of Abel integral operators and their relation to other integral transforms in various function spaces are investi- gated, questions of existence and uniqueness of solutions of linear and nonlinear Abel integral equations are treated, and for equatio...

  3. Analysis and design of a parallel-connected single active bridge DC-DC converter for high-power wind farm applications

    DEFF Research Database (Denmark)

    Park, Kiwoo; Chen, Zhe


    ripples without increasing switching losses or device stresses. Analysis of both the input and output current characteristics and design aspects of the transformer, the filter inductor, and the input and output filter capacitors will be presented. Considering the high maintenance cost and fault tolerant...

  4. An investigation of the influence of daily activities and location on personal exposure to air pollution in Dublin : measurement, analysis, modelling and application


    McCreddin, Andrew


    The research in this study was carried out to quantify real-time personal exposure to PM10 in a large number of individuals residing in the Dublin area. This was carried out in order to highlight activities and locations with high personal exposure concentrations of particulate matter. In addition, the dataset was analysed using various numerical, statistical, and other techniques to develop predictive modelling tools. The main subpopulation of individuals chosen for inclusion in the personal...

  5. Variance in total levels of phospholipase C zeta (PLC-ζ) in human sperm may limit the applicability of quantitative immunofluorescent analysis as a diagnostic indicator of oocyte activation capability. (United States)

    Kashir, Junaid; Jones, Celine; Mounce, Ginny; Ramadan, Walaa M; Lemmon, Bernadette; Heindryckx, Bjorn; de Sutter, Petra; Parrington, John; Turner, Karen; Child, Tim; McVeigh, Enda; Coward, Kevin


    To examine whether similar levels of phospholipase C zeta (PLC-ζ) protein are present in sperm from men whose ejaculates resulted in normal oocyte activation, and to examine whether a predominant pattern of PLC-ζ localization is linked to normal oocyte activation ability. Laboratory study. University laboratory. Control subjects (men with proven oocyte activation capacity; n = 16) and men whose sperm resulted in recurrent intracytoplasmic sperm injection failure (oocyte activation deficient [OAD]; n = 5). Quantitative immunofluorescent analysis of PLC-ζ protein in human sperm. Total levels of PLC-ζ fluorescence, proportions of sperm exhibiting PLC-ζ immunoreactivity, and proportions of PLC-ζ localization patterns in sperm from control and OAD men. Sperm from control subjects presented a significantly higher proportion of sperm exhibiting PLC-ζ immunofluorescence compared with infertile men diagnosed with OAD (82.6% and 27.4%, respectively). Total levels of PLC-ζ in sperm from individual control and OAD patients exhibited significant variance, with sperm from 10 out of 16 (62.5%) exhibiting levels similar to OAD samples. Predominant PLC-ζ localization patterns varied between control and OAD samples with no predictable or consistent pattern. The results indicate that sperm from control men exhibited significant variance in total levels of PLC-ζ protein, as well as significant variance in the predominant localization pattern. Such variance may hinder the diagnostic application of quantitative PLC-ζ immunofluorescent analysis. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  6. Biologically active extracts with kidney affections applications

    Energy Technology Data Exchange (ETDEWEB)

    Pascu, Mihaela, E-mail: [SC HOFIGAL S.A., Analytical Research Department, 2 Intr. Serelor, Bucharest-4 042124 (Romania); Politehnica University of Bucharest, Faculty of Applied Chemistry and Material Science, 1-5 Polizu Street, 11061 Bucharest (Romania); Pascu, Daniela-Elena [Politehnica University of Bucharest, Faculty of Applied Chemistry and Material Science, 1-5 Polizu Street, 11061 Bucharest (Romania); Cozea, Andreea [SC HOFIGAL S.A., Analytical Research Department, 2 Intr. Serelor, Bucharest-4 042124 (Romania); Transilvania University of Brasov, Faculty of Food and Tourism, 148 Castle Street, 500036 Brasov (Romania); Bunaciu, Andrei A. [SCIENT – Research Center for Instrumental Analysis, S.C. CROMATEC-PLUS S.R.L., 18 Sos. Cotroceni, Bucharest 060114 (Romania); Miron, Alexandra Raluca; Nechifor, Cristina Aurelia [Politehnica University of Bucharest, Faculty of Applied Chemistry and Material Science, 1-5 Polizu Street, 11061 Bucharest (Romania)


    Highlights: • The paper highlighted the compositional similarities and differences between the three extracts of bilberry and cranberry fruit derived from the same Ericaceae family. • A method of antioxidant activity, different cellulose membranes, a Whatman filter and Langmuir – kinetic model were used. • Arbutoside presence in all three extracts of bilberry and cranberry fruit explains their use in urinary infections – cystitis and colibacillosis. • Following these research studies, it was established that the fruits of bilberry and cranberry (fruit and leaves) significantly reduce the risk of urinary infections, and work effectively to protect against free radicals and inflammation. - Abstract: This paper is aimed to select plant materials rich in bioflavonoid compounds, made from herbs known for their application performances in the prevention and therapy of renal diseases, namely kidney stones and urinary infections (renal lithiasis, nephritis, urethritis, cystitis, etc.). This paper presents a comparative study of the medicinal plant extracts composition belonging to Ericaceae-Cranberry (fruit and leaves) – Vaccinium vitis-idaea L. and Bilberry (fruit) – Vaccinium myrtillus L. Concentrated extracts obtained from medicinal plants used in this work were analyzed from structural, morphological and compositional points of view using different techniques: chromatographic methods (HPLC), scanning electronic microscopy, infrared, and UV spectrophotometry, also by using kinetic model. Liquid chromatography was able to identify the specific compounds of the Ericaceae family, present in all three extracts, arbutosid, as well as specific components of each species, mostly from the class of polyphenols. The identification and quantitative determination of the active ingredients from these extracts can give information related to their therapeutic effects.

  7. Characterization of the major aroma-active compounds in mango (Mangifera indica L.) cultivars Haden, White Alfonso, Praya Sowoy, Royal Special, and Malindi by application of a comparative aroma extract dilution analysis. (United States)

    Munafo, John P; Didzbalis, John; Schnell, Raymond J; Schieberle, Peter; Steinhaus, Martin


    The aroma-active compounds present in tree-ripened fruits of the five mango (Mangifera indica L.) cultivars Haden, White Alfonso, Praya Sowoy, Royal Special, and Malindi were isolated by solvent extraction followed by solvent-assisted flavor evaporation (SAFE) and analyzed by gas chromatography-olfactometery (GC-O). Application of a comparative aroma extract dilution analysis (cAEDA) afforded 54 aroma-active compounds in the flavor dilution (FD) factor range from 4 to ≥2048, 16 of which are reported for the first time in mango. The results of the identification experiments in combination with the FD factors revealed 4-hydroxy-2,5-dimethyl-3(2H)-furanone as an important aroma compound in all cultivars analyzed. Twenty-seven aroma-active compounds were present in at least one mango cultivar at an FD factor ≥128. Clear differences in the FD factors of these odorants between each of the mango cultivars suggested that they contributed to the unique sensory profiles of the individual cultivars.

  8. New nano-complexes of Zn(II), Cu(II), Ni(II) and Co(II) ions; spectroscopy, thermal, structural analysis, DFT calculations and antimicrobial activity application (United States)

    El-Shafiy, Hoda F.; Saif, M.; Mashaly, Mahmoud M.; Halim, Shimaa Abdel; Eid, Mohamed F.; Nabeel, A. I.; Fouad, R.


    This work presents synthesis, characterization, and application of several metal (II) complexes with (E)-2-hydroxy-N/-((thiophen-2-yl)methylene)benzohydrazide (H2L). Prepared complexes were identified by elemental, thermal, FT-IR, UV-Vis, 1H NMR, and XRD analysis, as well as molar conductivity and magnetic moment measurements. Changes in FT-IR and 1H NMR spectra of hydrazone ligand upon coordination indicated that the ligand behaves the same way as a monoanonic ligand with ONS donor sites. Kinetic parameters were determined for each thermal degradation stage of the ligand and its complexes using 'Coats-Redfern' method. All results confirm that all prepared compounds have 1:2 metal-to-ligand stoichiometry except Zn(II) complex, which has 1:1 metal-to-ligand stoichiometry. The antimicrobial activity for complexes was investigated. The antimicrobial activity results revealed that Zn(II) complex (1) has a good potency against gram positive bacteria (E. coli) and gram negative bacteria (P. vulgaris) in comparision with doxymycin standard, AT B3LYP/6-311G (d,p) level, Density Functional Theory (DFT) calculations were carried out to investigate the optimized structure of both, the ligand and the complexes. Total energy, energy of HOMO, and LUMO as well as Mullikan atomic charges were calculated. Dipole moment, orientation, and structure activity relationship were performed and discussed.DFT calculations, moreover, confirmed practical antimicrobial results.

  9. Application of molecular connectivity and electro-topological indices in quantitative structure-activity analysis of pyrazole derivatives as inhibitors of factor Xa and thrombin. (United States)

    Krishnasamy, Chandravel; Raghuraman, Arjun; Kier, Lemont B; Desai, Umesh R


    Factor Xa and thrombin, two critical pro-coagulant enzymes of the clotting cascade, are the primary target of current anticoagulation research that aims to develop potent, orally bioavailable, synthetic small-molecule inhibitors. To determine structural features that might play important roles in factor Xa and thrombin recognition and oral bioavailability, quantitative structure-activity and structure-property analyses were performed on the factor Xa and thrombin inhibition data and Caco-2 cell-permeability data of 3-substituted pyrazole-5-carboxamides reported by Pinto et al. (J. Med. Chem. 2001, 44, 566). The factor Xa and thrombin inhibition potencies, and Caco-2 cell permeability of the 3-substituted pyrazole-5-carboxamides could be quantitatively described through molecular connectivity and atom level E-state indices. Different quantitative structure-activity and structure-property models were derived for each of the three biological properties. The models are statistically relevant with correlation coefficients of at least 0.9, and contain only two or three molecular descriptor variables. The study demonstrates the use of molecular connectivity and E-state indices in understanding factor Xa and thrombin inhibition. In addition, the models may be useful for predictive purposes in generating molecules with better potency, specificity, and oral bioavailability.

  10. Applications of random process excursion analysis

    CERN Document Server

    Brainina, Irina S


    This book addresses one of the key problems in signal processing, the problem of identifying statistical properties of excursions in a random process in order to simplify the theoretical analysis and make it suitable for engineering applications. Precise and approximate formulas are explained, which are relatively simple and can be used for engineering applications such as the design of devices which can overcome the high initial uncertainty of the self-training period. The information presented in the monograph can be used to implement adaptive signal processing devices capable of d

  11. Activity-Based Costing Application in an Urban Mass Transport Company

    National Research Council Canada - National Science Library

    Boris Popesko; Petr Novák


    .... The case study analysis showed the possible effects of the application of the Activity-Based Costing for an urban mass transport company as well as the limitations of using the ABC methodology in the service industry...

  12. Soils Activity Mobility Study: Methodology and Application

    Energy Technology Data Exchange (ETDEWEB)

    None, None


    This report presents a three-level approach for estimation of sediment transport to provide an assessment of potential erosion risk for sites at the Nevada National Security Site (NNSS) that are posted for radiological purposes and where migration is suspected or known to occur due to storm runoff. Based on the assessed risk, the appropriate level of effort can be determined for analysis of radiological surveys, field experiments to quantify erosion and transport rates, and long-term monitoring. The method is demonstrated at contaminated sites, including Plutonium Valley, Shasta, Smoky, and T-1. The Pacific Southwest Interagency Committee (PSIAC) procedure is selected as the Level 1 analysis tool. The PSIAC method provides an estimation of the total annual sediment yield based on factors derived from the climatic and physical characteristics of a watershed. If the results indicate low risk, then further analysis is not warranted. If the Level 1 analysis indicates high risk or is deemed uncertain, a Level 2 analysis using the Modified Universal Soil Loss Equation (MUSLE) is proposed. In addition, if a sediment yield for a storm event rather than an annual sediment yield is needed, then the proposed Level 2 analysis should be performed. MUSLE only provides sheet and rill erosion estimates. The U.S. Army Corps of Engineers Hydrologic Engineering Center-Hydrologic Modeling System (HEC-HMS) provides storm peak runoff rate and storm volumes, the inputs necessary for MUSLE. Channel Sediment Transport (CHAN-SED) I and II models are proposed for estimating sediment deposition or erosion in a channel reach from a storm event. These models require storm hydrograph associated sediment concentration and bed load particle size distribution data. When the Level 2 analysis indicates high risk for sediment yield and associated contaminant migration or when there is high uncertainty in the Level 2 results, the sites can be further evaluated with a Level 3 analysis using more complex

  13. Analysis, modeling, and simulation (AMS) testbed development and evaluation to support dynamic mobility applications (DMA) and active transportation and demand management (ATDM) programs -- calibration report for San Mateo testbed. (United States)


    The primary objective of this project is to develop multiple simulation Testbeds/transportation models to evaluate the impacts of DMA connected vehicle applications and the active and dynamic transportation management (ATDM) strategies. The outputs (...

  14. Adaptive Multi-Layer LMS Controller Design and Application to Active Vibration Suppression on a Truss and Proposed Impact Analysis Technique (United States)

    Barney, Timothy A.; Shin, Y. S.; Agrawal, B. N.


    This research develops an adaptive controller that actively suppresses a single frequency disturbance source at a remote position and tests the system on the NPS Space Truss. The experimental results are then compared to those predicted by an ANSYS finite element model. The NPS space truss is a 3.7-meter long truss that simulates a space-borne appendage with sensitive equipment mounted at its extremities. One of two installed piezoelectric actuators and an Adaptive Multi-Layer LMS control law were used to effectively eliminate an axial component of the vibrations induced by a linear proof mass actuator mounted at one end of the truss. Experimental and analytical results both demonstrate reductions to the level of system noise. Vibration reductions in excess of 50dB were obtained through experimentation and over 100dB using ANSYS, demonstrating the ability to model this system with a finite element model. This report also proposes a method to use distributed quartz accelerometers to evaluate the location, direction, and energy of impacts on the NPS space truss using the dSPACE data acquisition and processing system to capture the structural response and compare it to known reference Signals.

  15. Nonlinear analysis approximation theory, optimization and applications

    CERN Document Server


    Many of our daily-life problems can be written in the form of an optimization problem. Therefore, solution methods are needed to solve such problems. Due to the complexity of the problems, it is not always easy to find the exact solution. However, approximate solutions can be found. The theory of the best approximation is applicable in a variety of problems arising in nonlinear functional analysis and optimization. This book highlights interesting aspects of nonlinear analysis and optimization together with many applications in the areas of physical and social sciences including engineering. It is immensely helpful for young graduates and researchers who are pursuing research in this field, as it provides abundant research resources for researchers and post-doctoral fellows. This will be a valuable addition to the library of anyone who works in the field of applied mathematics, economics and engineering.

  16. Topics in mathematical analysis and applications

    CERN Document Server

    Tóth, László


    This volume presents significant advances in a number of theories and problems of Mathematical Analysis and its applications in disciplines such as Analytic Inequalities, Operator Theory, Functional Analysis, Approximation Theory, Functional Equations, Differential Equations, Wavelets, Discrete Mathematics and Mechanics. The contributions focus on recent developments and are written by eminent scientists from the international mathematical community. Special emphasis is given to new results that have been obtained in the above mentioned disciplines in which Nonlinear Analysis plays a central role. Some review papers published in this volume will be particularly useful for a broader readership in Mathematical Analysis, as well as for graduate students. An attempt is given to present all subjects in this volume in a unified and self-contained manner, to be particularly useful to the mathematical community.

  17. The Application of Crowd Sourcing in Educational Activities

    Directory of Open Access Journals (Sweden)

    Monika Skaržauskaitė


    Full Text Available Purpose—This paper analyses the role of crowdsourcing use in educational activities. In recent decades, the rapid growth of innovative Internet-based information and communication technologies created a new field of opportunities for educational organizations to reach their goals. Crowdsourcing, as defined by Jeff Howe (2006, is the act of taking a job traditionally performed by a designated employee and outsourcing it to an undefined, generally large group of people in the form of an open call. The newness of the term indicates that there is not significant literature on the subject of how this operating method is utilized in educational activities. The objective of this paper therefore is to take an exploratory look at how educational organizations are using crowdsourcing as part of their activities at the present time, and to suggest how the practice of crowdsourcing may spread to other educational activities as time goes on. Design/methodology/approach—The paper presents a conceptual model of crowdsourcing application in educational activities. The model is supported by analysis and synthesis of scientific literature and case studies. Findings—Analysis of literature and case studies allowed the creation of a conceptual model which shows the use of crowdsourcing in educational and supporting tasks of organizations. This tool will be helpful for future research on the subject, since it provides a framework of the analysis. Research limitations/implications—The model presented here is a conceptual model and needs to be validated empirically. Practical implications—For practical purposes, the variables proposed in the model would provide a more comprehensive framework for the assessment of crowdsourcing use in education activities and work as a guide for crowdsourcing strategies. Originality/Value—Although the relevant literature consists of many partial and indirect insights and indications in the direction as conceived by the model

  18. Analysis of 129I and its Application as Environmental Tracer

    DEFF Research Database (Denmark)

    Hou, Xiaolin; Hou, Yingkun


    as an environmental tracer has highly increased in the past 10 years. Neutron activation analysis and accelerator mass spectrometry are the only techniques for measurement of 129I at environmental level. This article mainly compares these two analytical techniques for the determination of 129I at environmental level......Iodine-129, the long-lived radioisotope of iodine, occurs naturally, but anthropogenic generated 129I has dominated the environment in the past 60 years. Due to active chemical and environmental properties of iodine and the enhanced analytical capacity for 129I measurement, the application of 129I...... mass. The speciation analysis of 129I can also be used to investigate the geochemical cycle of stable iodine. Some representative works on the environmental tracer application of 129I are summarized....

  19. Compositional Data Analysis Theory and Applications

    CERN Document Server

    Pawlowsky-Glahn, Vera


    This book presents the state-of-the-art in compositional data analysis and will feature a collection of papers covering theory, applications to various fields of science and software. Areas covered will range from geology, biology, environmental sciences, forensic sciences, medicine and hydrology. Key features:Provides the state-of-the-art text in compositional data analysisCovers a variety of subject areas, from geology to medicineWritten by leading researchers in the fieldIs supported by a website featuring R code

  20. Bio-inspired nanotechnology from surface analysis to applications

    CERN Document Server

    Walsh, Tiffany


    This book focuses on the use of bio-inspired and biomimetic methods for the fabrication and activation of nanomaterials. This includes studies concerning the binding of the biomolecules to the surface of inorganic structures, structure/function relationships of the final materials, and extensive discussions on the final applications of such biomimetic materials in unique applications including energy harvesting/storage, biomedical diagnostics, and materials assembly. This book also: ·          Covers the sustainable features of bio-inspired nanotechnology ·          Includes studies on the unique applications of biomimetic materials, such as energy harvesting and biomedical diagnostics Bio-Inspired Nanotechnology: From Surface Analysis to Applications is an ideal book for researchers, students, nanomaterials engineers, bioengineers, chemists, biologists, physicists, and medical researchers.

  1. Theory and applications of numerical analysis

    CERN Document Server

    Phillips, G M


    This text is a self-contained Second Edition, providing an introductory account of the main topics in numerical analysis. The book emphasizes both the theorems which show the underlying rigorous mathematics andthe algorithms which define precisely how to program the numerical methods. Both theoretical and practical examples are included.* a unique blend of theory and applications* two brand new chapters on eigenvalues and splines* inclusion of formal algorithms* numerous fully worked examples* a large number of problems, many with solutions



    E. Tsiliakou; E. Dimopoulou


    Indoor space differs from outdoor environments, since it is characterized by a higher level of structural complexity, geometry, as well as topological relations. Indoor space can be considered as the most important component in a building’s conceptual modelling, on which applications such as indoor navigation, routing or analysis are performed. Therefore, the conceptual meaning of sub spaces or the activities taking place in physical building boundaries (e.g. walls), require the comprehension...

  3. Multi-criteria analysis application in the investment projects assessment


    Popović, Žarko; Stanković, Jelena; Veselinović, Ivana


    The growth and development of each economic agent is inconceivable without investment or investment activity. In this sense, the investment decision plays a very important role in the realization of the development goals. Economically correct decision is based on the application of various methods of analysis of investment projects and the choice of the most acceptable one. Since a large number of factors affect the decision about the selection, the nature of the problem is multi-criteria. Th...

  4. Activity-Based Costing Application in an Urban Mass Transport Company


    Popesko Boris; Novák Petr


    The purpose of this paper is to provide a basic overview of the application of Activity-Based Costing in an urban mass transport company which operates land public transport via buses and trolleys within the city. The case study was conducted using the Activity-Based Methodology in order to calculate the true cost of individual operations and to measure the profitability of particular transport lines. The case study analysis showed the possible effects of the application of the Activity-Based...

  5. Diffractive micro-arrays for active spectroscopy and interconnect applications (United States)

    Castracane, James; Xu, Bai; Gutin, Olga N.; Lavrijsen, Rein; Stollenwerk, Andrew


    The use of Micro-Electro-Mechanical Systems (MEMS) technology has opened the door for many applications. In particular, by exploiting the reconfigurability of optical surfaces fabricated with this technology, many sensor, communication and spectroscopic systems can benefit. The controlled re-direction of single or multiple optical input sources can lend itself to high throughput sample analysis or massively parallel optical connectivity. In addition, the change in a MEMS-based optical surface can result in a flexible spectral analysis of incoming radiation. We report on the recent advances in our projects which are focused on the design/simulation, materials processing and integration issues involved with the creation and optimized operation of such diffractive micro-arrays. In this presentation, the state of the art in such devices will be presented which will include the process flow associated with production, structural metrology, optical performance, and parallel switching capabilities of the systems. The use of numerous materials including polysilicon, silicon dioxide and selected polymers as structural layers has enabled the production of devices which can be tailored for specific, performance related applications. Examples to be presented include diffractive surfaces with substantial (1 cm x 1 cm) active areas as well as large arrays with sub-micron feature sizes. Functional integration of the prototype devices include optical interconnects, active spectroscopy and bio/chem diagnostic systems.

  6. Statistical methods for active pharmacovigilance, with applications to diabetes drugs. (United States)

    Zhuo, Lan; Farrell, Patrick J; McNair, Doug; Krewski, Daniel


    Pharmacovigilance aims to identify adverse drug reactions using postmarket surveillance data under real-world conditions of use. Unlike passive pharmacovigilance, which is based on largely voluntary (and hence incomplete) spontaneous reports of adverse drug reactions with limited information on patient characteristics, active pharmacovigilance is based on electronic health records containing detailed information about patient populations, thereby allowing consideration of modifying factors such as polypharmacy and comorbidity, as well as sociodemographic characteristics. With the present shift toward active pharmacovigilance, statistical methods capable of addressing the complexities of such data are needed. We describe four such methods here, and demonstrate their application in the analysis of a large retrospective cohort of diabetics taking anti-hyperglycemic medications that may increase the risk of adverse cardiovascular events.


    Directory of Open Access Journals (Sweden)



    Full Text Available The purpose of the article is to emphasis that activity based costing is a proper tool for engineers to enhance their deci-sion-making process while developing new product. The theoretical analysis shows that variety of factors shall be en-compassed into new product decision-making process and therefore engineers and management should pay great attention to proper cost allocation. The paper suggests the usage of Activity Based Costing methodology for new product development decision-making process. Author states that application ABC in the process of rational decision-making referring to new product development enables managers and engineers to prioritize possible solutions, and reallocate resources used in production process in order to meet wider organizational goals. It would also contribute in coopera-tion of managers and engineers for the sake of organizational goal.

  8. Active nondestructive assay of nuclear materials: principles and applications

    Energy Technology Data Exchange (ETDEWEB)

    Gozani, Tsahi


    The purpose of this book is to present, coherently and comprehensively, the wealth of available but scattered information on the principles and applications of active nondestructive analysis (ANDA). Chapters are devoted to the following: background and overview; interactions of neutrons with matter; interactions of ..gamma..-rays with matter; neutron production and sources; ..gamma..-ray production and sources; effects of neutron and ..gamma..-ray transport in bulk media; signatures of neutron- and photon-induced fissions; neutron and photon detection systems and electronics; representative ANDA systems; and instrument analysis, calibration, and measurement control for ANDA. Each chapter has an introductory section describing the relationship of the topic of that chapter to ANDA. Each chapter ends with a section that summarizes the main results and conclusions of the chapter, and a reference list.

  9. Robust Algorithm Development for Application of Pinch Analysis on HEN

    Directory of Open Access Journals (Sweden)

    Ritesh Sojitra


    Full Text Available Since its genesis, Pinch Analysis is continuously evolving and its application is widening, reaching new horizons. The original concept of pinch approach was quite clear and, because of flexibility of this approach, innumerable applications have been developed in the industry. Consequently, a designer gets thoroughly muddled among these flexibilities. Hence, there was a need for a rigorous and robust model which could guide the optimisation engineer on deciding the applicability of the pinch approach and direct sequential step of procedure in predefined workflow, so that the precision of approach is ensured. Exploring the various options of a novice hands-on algorithm development that can be coded and interfaced with GUI and keeping in mind the difficulties faced by designers, an effort was made to formulate a new algorithm for the optimisation activity. As such, the work aims at easing out application hurdles and providing hands-on information to the Developer for use during preparation of new application tools. This paper presents a new algorithm, the application which ensures the Developer does not violate basic pinch rules. To achieve this, intermittent check gates are provided in the algorithm, which eliminate violation of predefined basic pinch rules, design philosophy, and Engineering Standards and ensure that constraints are adequately considered. On the other side, its sequential instruction to develop the pinch analysis and reiteration promises Maximum Energy Recovery (MER.

  10. Applications of fractal analysis to physiology (United States)

    Glenny, Robb W.; Robertson, H. Thomas; Yamashiro, Stanley; Bassingthwaighte, James B.


    This review describes approaches to the analysis of fractal properties of physiological observations. Fractals are useful to describe the natural irregularity of physiological systems because their irregularity is not truly random and can be demonstrated to have spatial or temporal correlation. The concepts of fractal analysis are introduced from intuitive, visual, and mathematical perspectives. The regional heterogeneities of pulmonary and myocardial flows are discussed as applications of spatial fractal analysis, and methods for estimating a fractal dimension from physiological data are presented. Although the methods used for fractal analyses of physiological data are still under development and will require additional validation, they appear to have great potential for the study of physiology at scales of resolution ranging from the microcirculation to the intact organism. PMID:1885430

  11. Application of critical path analysis in clinical trials. (United States)

    Kumar, Amal; Chakraborty, Bhaswat S


    Clinical research operates in a strictly regulated environment under various management models, but a distinct management model of clinical trial (CT) still needs exploration and research. Critical path analysis (CPA) is a management approach can be used for monitoring, analysis, and prediction of success of its time-bound operational activities. A model CT was compiled with 78 activities, which were further merged into 35 major activities. After performing dependence analysis, the list was finalized with 25 activities which were taken in activity predecessor to create a network diagram and perform CPA considering patients, conduct, and outcome. Activities were inclusive, described the trial entirely with accuracy, and were in chronological and logical sequences. This approach does not replace an understanding of or adherence to the requirements contained in all applicable regulations, guidelines or standard operating procedures governing clinical studies but ensures the proper use of operational and decisional approaches including optimal resource management. As the need to meet deadlines becomes more important and the need to produce good, stable project plans, CPA is very useful for determining activities that can lead to project delay. With this approach, project may be effectively monitored, and realistic schedules can be maintained.

  12. Application of critical path analysis in clinical trials

    Directory of Open Access Journals (Sweden)

    Amal Kumar


    Full Text Available Clinical research operates in a strictly regulated environment under various management models, but a distinct management model of clinical trial (CT still needs exploration and research. Critical path analysis (CPA is a management approach can be used for monitoring, analysis, and prediction of success of its time-bound operational activities. A model CT was compiled with 78 activities, which were further merged into 35 major activities. After performing dependence analysis, the list was finalized with 25 activities which were taken in activity predecessor to create a network diagram and perform CPA considering patients, conduct, and outcome. Activities were inclusive, described the trial entirely with accuracy, and were in chronological and logical sequences. This approach does not replace an understanding of or adherence to the requirements contained in all applicable regulations, guidelines or standard operating procedures governing clinical studies but ensures the proper use of operational and decisional approaches including optimal resource management. As the need to meet deadlines becomes more important and the need to produce good, stable project plans, CPA is very useful for determining activities that can lead to project delay. With this approach, project may be effectively monitored, and realistic schedules can be maintained.

  13. Time series analysis time series analysis methods and applications

    CERN Document Server

    Rao, Tata Subba; Rao, C R


    The field of statistics not only affects all areas of scientific activity, but also many other matters such as public policy. It is branching rapidly into so many different subjects that a series of handbooks is the only way of comprehensively presenting the various aspects of statistical methodology, applications, and recent developments. The Handbook of Statistics is a series of self-contained reference books. Each volume is devoted to a particular topic in statistics, with Volume 30 dealing with time series. The series is addressed to the entire community of statisticians and scientists in various disciplines who use statistical methodology in their work. At the same time, special emphasis is placed on applications-oriented techniques, with the applied statistician in mind as the primary audience. Comprehensively presents the various aspects of statistical methodology Discusses a wide variety of diverse applications and recent developments Contributors are internationally renowened experts in their respect...


    Energy Technology Data Exchange (ETDEWEB)

    R.J. Garrett


    The purpose of this internal hazards analysis is to identify and document the internal hazards and potential initiating events associated with preclosure operations of the repository at Yucca Mountain. Internal hazards are those hazards presented by the operation of the facility and by its associated processes that can potentially lead to a radioactive release or cause a radiological hazard. In contrast to external hazards, internal hazards do not involve natural phenomena and external man-made hazards. This internal hazards analysis was performed in support of the preclosure safety analysis and the License Application for the Yucca Mountain Project. The methodology for this analysis provides a systematic means to identify internal hazards and potential initiating events that may result in a radiological hazard or radiological release during the repository preclosure period. These hazards are documented in tables of potential internal hazards and potential initiating events (Section 6.6) for input to the repository event sequence categorization process. The results of this analysis will undergo further screening and analysis based on the criteria that apply to the performance of event sequence analyses for the repository preclosure period. The evolving design of the repository will be re-evaluated periodically to ensure that internal hazards that have not been previously evaluated are identified.

  15. Information theory applications for biological sequence analysis. (United States)

    Vinga, Susana


    Information theory (IT) addresses the analysis of communication systems and has been widely applied in molecular biology. In particular, alignment-free sequence analysis and comparison greatly benefited from concepts derived from IT, such as entropy and mutual information. This review covers several aspects of IT applications, ranging from genome global analysis and comparison, including block-entropy estimation and resolution-free metrics based on iterative maps, to local analysis, comprising the classification of motifs, prediction of transcription factor binding sites and sequence characterization based on linguistic complexity and entropic profiles. IT has also been applied to high-level correlations that combine DNA, RNA or protein features with sequence-independent properties, such as gene mapping and phenotype analysis, and has also provided models based on communication systems theory to describe information transmission channels at the cell level and also during evolutionary processes. While not exhaustive, this review attempts to categorize existing methods and to indicate their relation with broader transversal topics such as genomic signatures, data compression and complexity, time series analysis and phylogenetic classification, providing a resource for future developments in this promising area.

  16. Active elastic metamaterials with applications in acoustics


    Pope, Simon; Laalej, Hatim; Daley, Steve


    International audience; Elastic metamaterials provide a new approach to solving existing problems in acoustics. They have also been associated with novel concepts such as acoustic invisibility and subwavelength imaging. To be applied to many of the proposed applications a metamaterial would need to have the desired mass density and elastic moduli over a wide frequency band. To minimise scatter in acoustics applications the impedance of solid elastic metamaterials also need to be matched to th...


    Directory of Open Access Journals (Sweden)

    W. Pervez


    Full Text Available Rapid advancement in remote sensing open new avenues to explore the hyperspectral Hyperion imagery pre-processing techniques, analysis and application for land use mapping. The hyperspectral data consists of 242 bands out of which 196 calibrated/useful bands are available for hyperspectral applications. Atmospheric correction applied to the hyperspectral calibrated bands make the data more useful for its further processing/ application. Principal component (PC analysis applied to the hyperspectral calibrated bands reduced the dimensionality of the data and it is found that 99% of the data is held in first 10 PCs. Feature extraction is one of the important application by using vegetation delineation and normalized difference vegetation index. The machine learning classifiers uses the technique to identify the pixels having significant difference in the spectral signature which is very useful for classification of an image. Supervised machine learning classifier technique has been used for classification of hyperspectral image which resulted in overall efficiency of 86.6703 and Kappa co-efficient of 0.7998.

  18. Dynamic Analysis of Mobile Device Applications

    Energy Technology Data Exchange (ETDEWEB)

    Corey Thuen


    The On-Device Dynamic Analysis of Mobile Applications (ODAMA) project was started in an effort to protect mobile devices used in Industrial Control Systems (ICS) from cyber attack. Because mobile devices hide as much of the “computer” as possible, the user’s ability to assess the software running on their system is limited. The research team chose Google’s Android platform for this initial research because it is open source and it would give us freedom in our approach, including the ability to modify the mobile device’s operating system itself. The research team concluded that a Privileged Application was the right approach, and the result was ODAMA. This project is an important piece of the work to secure the expanding use of mobile devices with our nation’s critical infrastructure.

  19. Comparative Analysis of Virtual Education Applications

    Directory of Open Access Journals (Sweden)

    Mehmet KURT


    Full Text Available The research was conducted in order to make comparative analysis of virtual education applications. The research is conducted in survey model. The study group consists of total 300 institutes providing virtual education in the fall, spring and summer semesters of 2004; 246 in USA, 10 in Australia, 3 in South Africa, 10 in India, 21 in UK, 6 in Japan, 4 in Turkey. The information has been collected by online questionnaire sent to the target mass by e-mail. The questionnaire has been developed in two information categories as personal information and institutes and their virtual education applications. The English web design of the online questionnaire and the database has been prepared by Microsoft ASP codes which is the script language of Microsoft Front Page editor and has been tested on personal web site. The questionnaire has been pre applied in institutions providing virtual education in Australia. The English text of the questionnaire and web site design have been sent to educational technology and virtual education specialists in the countries of the study group. With the feedback received, the spelling mistakes have been corrected and concept and language validity have been completed. The application of the questionnaire has taken 40 weeks during March-November 2004. Only 135 institutes have replied. Two of the questionnaires have been discharged because they included mistaken coding, names of the institutions and countries. Valid 133 questionnaires cover approximately 44% of the study group. Questionnaires saved in the online database have been transferred to Microsoft Excel and then to SPSS by external database connection. In regards of the research objectives, the data collected has been analyzed on computer and by using SPSS statistics package program. In data analysis frequency (f, percentage (% and arithmetic mean ( have been used. In comparisons of country, institute, year, and other variables, che-square test, independent t

  20. Application of the reliability analysis to the wastewater plant. Activated sludge pure oxygen system; Applicazione dell'analisi di affidabilita' alla depurazione delle acque. Impianto a fanghi attivi ad ossigeno puro

    Energy Technology Data Exchange (ETDEWEB)

    Corti, A. [Florence Univ., Florence (Italy). Dipt. di Energetica Sergio Stecco; Giagnoni, L. [Florence Univ., Florence (Italy). Dipt. di Energetica Sergio Stecco, Sez. Impianti e Tecnologie Industriali; Sirini, P. [Florence Univ., Florence (Italy). Dipt. di Ingegneria Civile


    The application of the reliability analysis to the wastewater plant is a valid and favorable instrument for the location of able managerial and/or structural participation to improve not only the emergency, but also the activity to obtain a product of optimal characteristics to several regimes (in the specific case the quality of effluent, the recovery of energy form the digestion processes, etc.) Moreover, the analysis techniques allow to indicate and to quantify the probability to create a crisis in to the system to the several steps it is subordinate during the own life utility. The wastewater process cannot be sure considered stationary. This variability can be controlled through one corrected appraisal in project and managerial activity equipping the system of great flexibility. In this way, the reliability analysis widens its range and it searches not only the single event able to produce a damage to the structure, but also that one is able to alter the final product. With this attempt, the classic techniques have been applied. Analysis, (Fault tree Analysis) to Bologna's wastewater treatment (pure oxygen system). [Italian] L'applicazione dell'analisi di affidabilita' agli impianti di depurazione si presenta come un valido e vantaggioso strumento per l'individuazione di interventi gestionali e/o strutturali capaci di migliorare non solo la sicurezza, ma anche l'attivita' depurativa al fine di ottenere un prodotto di caratteristiche ottimali ai vari regimi. Questo equiavale a dire, nel caso specifico, poter valutare la costanza dei termini di qualita' dell'effluente in uscita e del recupero di energia dai processi di digestione dei fanghi. Le tecniche di analisi di affidabilita' permettono di indicare e quantificare la probabilita' di eventi capaci di mettere in crisi l'attivita' stessa dell'impianto alle varie sollecitazioni a cui e' sottoposto durante la propria vita utile. Il

  1. Sentiment analysis algorithms and applications: A survey

    Directory of Open Access Journals (Sweden)

    Walaa Medhat


    Full Text Available Sentiment Analysis (SA is an ongoing field of research in text mining field. SA is the computational treatment of opinions, sentiments and subjectivity of text. This survey paper tackles a comprehensive overview of the last update in this field. Many recently proposed algorithms' enhancements and various SA applications are investigated and presented briefly in this survey. These articles are categorized according to their contributions in the various SA techniques. The related fields to SA (transfer learning, emotion detection, and building resources that attracted researchers recently are discussed. The main target of this survey is to give nearly full image of SA techniques and the related fields with brief details. The main contributions of this paper include the sophisticated categorizations of a large number of recent articles and the illustration of the recent trend of research in the sentiment analysis and its related areas.

  2. Malware Instrumentation Application to Regin Analysis

    Directory of Open Access Journals (Sweden)

    Matthieu Kaczmarek


    Full Text Available The complexity of the Regin malware underlines the importance of reverse engineering in modern incident response. The present study shows that such complexity can be overcome: substantial information about adversary tactics, techniques and procedures is obtained from reverse engineering. An introduction to the Regin development framework is provided along with instrumentation guidelines. Such instrumentation enables experimentation with malware modules. So analysis can derectly leverage malware’s own code without the need to program an analysis toolkit. As an application of the presented instrumentation, the underlying botnet architecture is analysed. Finally conclusions from different perspectives are provided: defense, attack and counter intelligence.

  3. Creep analysis of silicone for podiatry applications. (United States)

    Janeiro-Arocas, Julia; Tarrío-Saavedra, Javier; López-Beceiro, Jorge; Naya, Salvador; López-Canosa, Adrián; Heredia-García, Nicolás; Artiaga, Ramón


    This work shows an effective methodology to characterize the creep-recovery behavior of silicones before their application in podiatry. The aim is to characterize, model and compare the creep-recovery properties of different types of silicone used in podiatry orthotics. Creep-recovery phenomena of silicones used in podiatry orthotics is characterized by dynamic mechanical analysis (DMA). Silicones provided by Herbitas are compared by observing their viscoelastic properties by Functional Data Analysis (FDA) and nonlinear regression. The relationship between strain and time is modeled by fixed and mixed effects nonlinear regression to compare easily and intuitively podiatry silicones. Functional ANOVA and Kohlrausch-Willians-Watts (KWW) model with fixed and mixed effects allows us to compare different silicones observing the values of fitting parameters and their physical meaning. The differences between silicones are related to the variations of breadth of creep-recovery time distribution and instantaneous deformation-permanent strain. Nevertheless, the mean creep-relaxation time is the same for all the studied silicones. Silicones used in palliative orthoses have higher instantaneous deformation-permanent strain and narrower creep-recovery distribution. The proposed methodology based on DMA, FDA and nonlinear regression is an useful tool to characterize and choose the proper silicone for each podiatry application according to their viscoelastic properties. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Active Millimeter and Submillimeter Sensing Applications Project (United States)

    National Aeronautics and Space Administration — The workshop will have three main objectives. The first will be to inventory the signatures and measurements that are desirable to make using submillimeter active...

  5. Phytochemical analysis and antioxidant activities of Combretum ...

    African Journals Online (AJOL)

    Phytochemical analysis and antioxidant activities of Combretum molle and Pericopsis laxiflora. Kossi-Kuma Agbalevon Koevi, Vinsoun Millogo, Jean Baptiste Hzounda Fokou, Abdou Sarr, Georges Anicet Ouedraogo, Emmanuel Bassene ...

  6. Overview of smartphone applications for sleep analysis

    Directory of Open Access Journals (Sweden)

    Adrian A. Ong


    Full Text Available Objective: To review and assess the current selection of sleep analysis smartphone applications (apps available for download. Methods: The iOS and Google Play mobile app store were searched for sleep analysis apps targeted for consumer use. Alarm clock, sleep-aid, snoring and sleep-talking recorder, fitness tracker apps, and apps geared towards health professionals were excluded. App information and features were obtained from in-store descriptions, and the app developer website. Results: A total of 51 unique sleep apps in both iOS and Google Play stores were included. The apps were rated 3.8/5 in both stores, and had an average price of $1.12 in the iOS store and $0.58 in the Google Play store. >65% of sleep apps report on sleep structure, including duration, time awake, and time in light/deep sleep, while reporting of REM was limited. The availability of extra features was variable, ranging from 4% to 73% of apps. Conclusions: There are a variety of sleep analysis apps with a range of functionality. The apps with the most reviews from the each store are featured. Many apps provide data on sleep structure; however the algorithms are not validated by scientific literature or studies. Since patients may inquire about their sleep habits from these apps, it is necessary for physicians to be aware of the most common apps and the features offered and their limitations in order to properly counsel patients. Keywords: Mobile applications, Smartphone, Apps, Sleep monitor, Actigraphy

  7. Activity Recognition Using Inertial Sensing for Healthcare, Wellbeing and Sports Applications: A Survey

    NARCIS (Netherlands)

    Avci, A.; Bosch, S.; Marin Perianu, Mihai; Marin Perianu, Raluca; Havinga, Paul J.M.

    This paper surveys the current research directions of activity recognition using inertial sensors, with potential application in healthcare, wellbeing and sports. The analysis of related work is organized according to the five main steps involved in the activity recognition process: preprocessing,

  8. Acceleration of Data Analysis Applications using GPUs (United States)

    Fillmore, D.; Messmer, P.; Mullowney, P.; Amyx, K.


    The vast amount of data collected by present and future scientific instruments, sensors and numerical models requires a significant increase in computing power for analysis. In many cases, processing time on a single workstation becomes impractical. While clusters of commodity processors can be utilized to accelerate some of these tasks, the relatively high software development cost, as well as acquisition and operational costs, make them less attractive for broad use. Over the past few years, another class of architectures has gained some popularity, namely heterogeneous architectures, which consist of general purpose processors connected to specialized processors. One of the most prominent examples are Graphics Processing Units (GPUs), which offer a tremendous amount of floating-point processing power due to demand for high-quality graphics in the computer game market. However, in order to harness this processing power, software developers have to develop with a detailed understanding of the underlying hardware. This burden on the developer is often hardly justifiable considering the rapid evolution of the hardware. In this talk, we will introduce GPULib, an open source library that enables scientists to accelerate their data analysis tasks using the GPUs already installed in their system from within high-level languages like IDL or MATLAB, and present examples and possible speedup from real-world data analysis applications. This work is funded through NASA Phase II SBIR Grant NNG06CA13C.

  9. Designing Interactive Applications to Support Novel Activities

    NARCIS (Netherlands)

    H. Lee (Hyowon); N. Mohamad Ali; L. Hardman (Lynda)


    htmlabstractR&D in media-related technologies including multimedia, information retrieval, computer vision, and the semantic web is experimenting on a variety of computational tools that, if sufficiently matured, could support many novel activities that are not practiced today. Interactive

  10. Tongue Color Analysis for Medical Application

    Directory of Open Access Journals (Sweden)

    Bob Zhang


    Full Text Available An in-depth systematic tongue color analysis system for medical applications is proposed. Using the tongue color gamut, tongue foreground pixels are first extracted and assigned to one of 12 colors representing this gamut. The ratio of each color for the entire image is calculated and forms a tongue color feature vector. Experimenting on a large dataset consisting of 143 Healthy and 902 Disease (13 groups of more than 10 samples and one miscellaneous group, a given tongue sample can be classified into one of these two classes with an average accuracy of 91.99%. Further testing showed that Disease samples can be split into three clusters, and within each cluster most if not all the illnesses are distinguished from one another. In total 11 illnesses have a classification rate greater than 70%. This demonstrates a relationship between the state of the human body and its tongue color.

  11. The applicability and effectiveness of cluster analysis (United States)

    Ingram, D. S.; Actkinson, A. L.


    An insight into the characteristics which determine the performance of a clustering algorithm is presented. In order for the techniques which are examined to accurately cluster data, two conditions must be simultaneously satisfied. First the data must have a particular structure, and second the parameters chosen for the clustering algorithm must be correct. By examining the structure of the data from the Cl flight line, it is clear that no single set of parameters can be used to accurately cluster all the different crops. The effectiveness of either a noniterative or iterative clustering algorithm to accurately cluster data representative of the Cl flight line is questionable. Thus extensive a prior knowledge is required in order to use cluster analysis in its present form for applications like assisting in the definition of field boundaries and evaluating the homogeneity of a field. New or modified techniques are necessary for clustering to be a reliable tool.

  12. Framelets and wavelets algorithms, analysis, and applications

    CERN Document Server

    Han, Bin


    Marking a distinct departure from the perspectives of frame theory and discrete transforms, this book provides a comprehensive mathematical and algorithmic introduction to wavelet theory. As such, it can be used as either a textbook or reference guide. As a textbook for graduate mathematics students and beginning researchers, it offers detailed information on the basic theory of framelets and wavelets, complemented by self-contained elementary proofs, illustrative examples/figures, and supplementary exercises. Further, as an advanced reference guide for experienced researchers and practitioners in mathematics, physics, and engineering, the book addresses in detail a wide range of basic and advanced topics (such as multiwavelets/multiframelets in Sobolev spaces and directional framelets) in wavelet theory, together with systematic mathematical analysis, concrete algorithms, and recent developments in and applications of framelets and wavelets. Lastly, the book can also be used to teach on or study selected spe...

  13. Application of activity - based costing in companies in Poland

    National Research Council Canada - National Science Library

    Wnuk-Pel, Tomasz


    The purpose of this paper is to explore the application of activity-based costing in companies in Poland, and more specifically, to analyse problems in ABC implementation, the structure of ABC systems...

  14. PREFACE: Dielectrics 2009: Measurement Analysis and Applications (United States)

    Vaughan, Alun; Williams, Graham


    The conference Dielectrics 2009: Measurements, Analysis and Applications represents a significant milestone in the evolution of dielectrics research in the UK. It is reasonable to state that the academic study of dielectrics has led to many fundamental advances and that dielectric materials underpin the modern world in devices ranging from field effect transistors, which operate at extremely high fields, albeit low voltages, to the high voltage plants that provide the energy that powers our economy. The origins of the Dielectrics Group of the Institute of Physics (IOP), which organized this conference, can be traced directly back to the early 1960s, when Professor Mansel Davies was conducting research into the dielectric relaxation behaviour of polar liquids and solids at The Edward Davies Chemical Laboratories of the University College of Wales, Aberystwyth. He was already well-known internationally for his studies of molecular structure and bonding of small molecules, using infra-red-spectroscopy, and of the physical properties of hydrogen-bonded liquids and solids, using thermodynamic methods. Dielectric spectroscopy was a fairly new area for him and he realized that opportunities for scientists in the UK to gather together and discuss their research in this developing area of physical chemistry/chemical physics were very limited. He conceived the idea of forming a Dielectrics Discussion Group (DDG), which would act as a meeting point and provide a platform for dielectrics research in the UK and beyond and, as a result, a two-day Meeting was convened in the spring of 1968 at Gregynog Hall of the University of Wales, near Newtown, Montgomeryshire. It was organized by Mansel Davies, Alun Price and Graham Williams, all physical chemists from the UCW, Aberystwyth. Fifty scientists attended, being a mix of physical chemists, theoretical chemists, physicists, electrical engineers, polymer and materials scientists, all from the UK, except Dr Brendan Scaife of Trinity

  15. Self-Timed Scheduling Analysis for Real-Time Applications

    Directory of Open Access Journals (Sweden)

    Marco J. G. Bekooij


    Full Text Available This paper deals with the scheduling analysis of hard real-time streaming applications. These applications are mapped onto a heterogeneous multiprocessor system-on-chip (MPSoC, where we must jointly meet the timing requirements of several jobs. Each job is independently activated and processes streams at its own rate. The dynamic starting and stopping of jobs necessitates the usage of self-timed schedules (STSs. By modeling job implementations using multirate data flow (MRDF graph semantics, real-time analysis can be performed. Traditionally, temporal analysis of STSs for MRDF graphs only aims at evaluating the average throughput. It does not cope well with latency, and it does not take into account the temporal behavior during the initial transient phase. In this paper, we establish an important property of STSs: the initiation times of actors in an STS are bounded by the initiation times of the same actors in any static periodic schedule of the same job; based on this property, we show how to guarantee strictly periodic behavior of a task within a self-timed implementation; then, we provide useful bounds on maximum latency for jobs with periodic, sporadic, and bursty sources, as well as a technique to check latency requirements. We present two case studies that exemplify the application of these techniques: a simplified channel equalizer and a wireless LAN receiver.

  16. Self-Timed Scheduling Analysis for Real-Time Applications (United States)

    Moreira, Orlando M.; Bekooij, Marco J. G.


    This paper deals with the scheduling analysis of hard real-time streaming applications. These applications are mapped onto a heterogeneous multiprocessor system-on-chip (MPSoC), where we must jointly meet the timing requirements of several jobs. Each job is independently activated and processes streams at its own rate. The dynamic starting and stopping of jobs necessitates the usage of self-timed schedules (STSs). By modeling job implementations using multirate data flow (MRDF) graph semantics, real-time analysis can be performed. Traditionally, temporal analysis of STSs for MRDF graphs only aims at evaluating the average throughput. It does not cope well with latency, and it does not take into account the temporal behavior during the initial transient phase. In this paper, we establish an important property of STSs: the initiation times of actors in an STS are bounded by the initiation times of the same actors in any static periodic schedule of the same job; based on this property, we show how to guarantee strictly periodic behavior of a task within a self-timed implementation; then, we provide useful bounds on maximum latency for jobs with periodic, sporadic, and bursty sources, as well as a technique to check latency requirements. We present two case studies that exemplify the application of these techniques: a simplified channel equalizer and a wireless LAN receiver.

  17. Extreme learning machine for ranking: generalization analysis and applications. (United States)

    Chen, Hong; Peng, Jiangtao; Zhou, Yicong; Li, Luoqing; Pan, Zhibin


    The extreme learning machine (ELM) has attracted increasing attention recently with its successful applications in classification and regression. In this paper, we investigate the generalization performance of ELM-based ranking. A new regularized ranking algorithm is proposed based on the combinations of activation functions in ELM. The generalization analysis is established for the ELM-based ranking (ELMRank) in terms of the covering numbers of hypothesis space. Empirical results on the benchmark datasets show the competitive performance of the ELMRank over the state-of-the-art ranking methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. Oscillator circuits frontiers in design, analysis and applications

    CERN Document Server


    This book surveys recent developments in the design, analysis and applications of oscillator circuit design. It highlights developments in the analysis of synchronization and wave phenomena, new analytical and design methods and their application, and novel engineering applications of oscillator circuits.

  19. 3D Network Analysis for Indoor Space Applications (United States)

    Tsiliakou, E.; Dimopoulou, E.


    Indoor space differs from outdoor environments, since it is characterized by a higher level of structural complexity, geometry, as well as topological relations. Indoor space can be considered as the most important component in a building's conceptual modelling, on which applications such as indoor navigation, routing or analysis are performed. Therefore, the conceptual meaning of sub spaces or the activities taking place in physical building boundaries (e.g. walls), require the comprehension of the building's indoor hierarchical structure. The scope of this paper is to perform 3D network analysis in a building's interior and is structured as follows: In Section 1 the definition of indoor space is provided and indoor navigation requirements are analysed. Section 2 describes the processes of indoor space modeling, as well as routing applications. In Section 3, a case study is examined involving a 3D building model generated in CityEngine (exterior shell) and ArcScene (interior parts), in which the use of commercially available software tools (ArcGIS, ESRI), in terms of indoor routing and 3D network analysis, are explored. The fundamentals of performing 3D analysis with the ArcGIS Network Analyst extension were tested. Finally a geoprocessing model was presented, which was specifically designed to be used to interactively find the best route in ArcScene. The paper ends with discussion and concluding remarks on Section 4.


    Directory of Open Access Journals (Sweden)

    E. Tsiliakou


    Full Text Available Indoor space differs from outdoor environments, since it is characterized by a higher level of structural complexity, geometry, as well as topological relations. Indoor space can be considered as the most important component in a building’s conceptual modelling, on which applications such as indoor navigation, routing or analysis are performed. Therefore, the conceptual meaning of sub spaces or the activities taking place in physical building boundaries (e.g. walls, require the comprehension of the building’s indoor hierarchical structure. The scope of this paper is to perform 3D network analysis in a building’s interior and is structured as follows: In Section 1 the definition of indoor space is provided and indoor navigation requirements are analysed. Section 2 describes the processes of indoor space modeling, as well as routing applications. In Section 3, a case study is examined involving a 3D building model generated in CityEngine (exterior shell and ArcScene (interior parts, in which the use of commercially available software tools (ArcGIS, ESRI, in terms of indoor routing and 3D network analysis, are explored. The fundamentals of performing 3D analysis with the ArcGIS Network Analyst extension were tested. Finally a geoprocessing model was presented, which was specifically designed to be used to interactively find the best route in ArcScene. The paper ends with discussion and concluding remarks on Section 4.

  1. Analysis of the activity pattern of volcanoes through self-organized crack networks: The effect of density barriers—An application to Vesuvius activity in the period 1631-1944 (United States)

    Piegari, E.; Di Maio, R.; Scandone, R.


    We simulated the pattern of activity of a strato-volcano by using a cellular automaton model where magma is allowed to ascend to the surface through self-organized crack networks. Magma rises toward the surface by filling connected paths of fractures until the magma's density is less than that of surrounding rocks. If magma enters a region with negative or neutral buoyancy, it cools and solidifies; as a result, the local density profile is modified, and magmatic dikes are formed. We simulated the temporal evolution of high-density pathways of dikes that magma may eventually utilize to reach the surface. We showed that if a shallow neutral-negative buoyancy zone is restored after eruptions, due to, for example, piecemeal or chaotic collapses, a characteristic timescale appears in the inter-event repose time distribution. Such characteristic repose time represents the average time that magma takes to form a high-density pathway through the less dense rock layer, and it may give a hint to predict possible eruptive scenarios. Even if the model includes many simplifying assumptions in the definition of magma-rock interaction, the results obtained from simulations are consistent with the eruptive behavior of the Mt. Somma-Vesuvius volcano for the 1631-1944 period.

  2. Modeling the Benchmark Active Control Technology Wind-Tunnel Model for Active Control Design Applications (United States)

    Waszak, Martin R.


    This report describes the formulation of a model of the dynamic behavior of the Benchmark Active Controls Technology (BACT) wind tunnel model for active control design and analysis applications. The model is formed by combining the equations of motion for the BACT wind tunnel model with actuator models and a model of wind tunnel turbulence. The primary focus of this report is the development of the equations of motion from first principles by using Lagrange's equations and the principle of virtual work. A numerical form of the model is generated by making use of parameters obtained from both experiment and analysis. Comparisons between experimental and analytical data obtained from the numerical model show excellent agreement and suggest that simple coefficient-based aerodynamics are sufficient to accurately characterize the aeroelastic response of the BACT wind tunnel model. The equations of motion developed herein have been used to aid in the design and analysis of a number of flutter suppression controllers that have been successfully implemented.

  3. Applications of nonlinear time-series analysis (United States)

    Nichols, Jonathan Michael

    In this work, new applications in chaos theory and nonlinear time-series analysis are explored. Tools for attractor-based analysis are developed along with a complete description of invariant measures. The focus is on the computation of dimension and Lyapunov spectra from a single time-history for the purposes of system identification. The need for accurate attractor reconstruction is stressed as it may have severe effects on the quality of estimated invariants and of attractor based predictions. These tools are then placed in the context of several different problems of importance to the engineering community. Dimension and Lyaponuv spectra are used to indicate the operating regime of a nonlinear mechanical oscillator. Subtle changes to the way in which the oscillator is forced may give rise to a response with different state space characteristics. These differences are clearly discernible using invariant measures yet are undetectable using linear-based techniques. A state space approach is also used to extract damping estimates from the oscillator by means of the complete Lyapunov spectrum. The sum of the exponents may be thought of as the average divergence of the system which will, for a viscous damping model, provide quantitative information about the coefficient of viscous damping. The notion of chaotic excitation of a linear system is also explored. A linear structure subject to chaotic excitation will effectively act as a filter. The resulting dynamical interaction gives rise to response (filtered) attractors which possess information about the linear system. Differences in the geometric properties of the filtered attractors are used to detect damage in structures. These attractor-based statistics are shown to be more robust indicators of damage than linear-based statistics (e.g. mode shapes, frequencies, etc.). The same procedure is also used to estimate the coefficient of viscous damping for a multi-degree-of-freedom linear structure.

  4. Elemental Analysis and Biological Activities of Chrysophyllum ...

    African Journals Online (AJOL)

    The present study was performed to estimate elementals and to determine bioactivities namely anticariogenic, antioxidant, pancreatic lipase inhibitory and cytotoxic activity of Chrysophyllum roxburghii leaves. Elemental analysis revealed that calcium and manganese were present in high concentration among principal and ...

  5. Prompt gamma-ray activation analysis (PGAA)

    Energy Technology Data Exchange (ETDEWEB)

    Kern, J. [Fribourg Univ. (Switzerland). Inst. de Physique


    The paper deals with a brief description of the principles of prompt gamma-ray activation analysis (PGAA), with the detection of gamma-rays, the PGAA project at SINQ and with the expected performances. 8 figs., 3 tabs., 10 refs.

  6. System Safety Analysis Application Guide. Safety Analysis Report Update Program

    Energy Technology Data Exchange (ETDEWEB)


    Martin Marietta Energy Systems, Inc., (Energy Systems) is committed to performing and documenting safety analyses for facilities it manages for the Department of Energy (DOE). Safety analyses are performed to identify hazards and potential accidents; to analyze the adequacy of measures taken to eliminate, control, or mitigate hazards; and to evaluate potential accidents and determine associated risks. Safety Analysis Reports (SARs) are prepared to document the safety analysis to ensure facilities can be operated safely and in accordance with regulations. SARs include Technical Safety Requirements (TSRs), which are specific technical and administrative requirements that prescribe limits and controls to ensure safe operation of DOE facilities. These documented descriptions and analyses contribute to the authorization basis for facility operation. Energy Systems has established a process to perform Unreviewed Safety Question Determinations (USQDs) for planned changes and as-found conditions that are not described and analyzed in existing safety analyses. The process evaluates changes and as-found conditions to determine whether revisions to the authorization basis must be reviewed and approved by DOE. There is an Unreviewed Safety Question (USQ) if a change introduces conditions not bounded by the facility authorization basis. When it is necessary to request DOE approval to revise the authorization basis, preparation of a System Safety Analysis (SSA) is recommended. This application guide describes the process of preparing an SSA and the desired contents of an SSA. Guidance is provided on how to identify items and practices which are important to safety; how to determine the credibility and significance of consequences of proposed accident scenarios; how to evaluate accident prevention and mitigation features of the planned change; and how to establish special requirements to ensure that a change can be implemented with adequate safety.

  7. Highly integrated application specific MMICs for active phased array radar applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den


    Application specific MMIC solutions for active array radar, developed at TNO-FEL, are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart

  8. Highly Integrated Application Specific MMICS for Active Phased Array Radar Applications

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den


    Application specific MMIC solutions for active array radar, developed at TNO-FEL. are presented. The use and application of these MMICs in their respective radar systems will be shown. These MMICs address the needs for current and future phased-array topologies as for example the concept of "smart

  9. Somatotype analysis of physically active individuals. (United States)

    Almeida, A H S; Santos, S A G; Castro, P J P; Rizzo, J A; Batista, G R


    The present study aimed at comparing demographic variables, physical activity level, and health-related anthropometric indicators according to somatotype among physically active individuals. This is a descriptive cross-sectional study, in which the sample consisted of 304 individuals, who are users of the jogging track at the Federal University of Pernambuco (UFPE) in Recife, state of Pernambuco, northeastern Brazil. Somatotypes were analyzed using the anthropometric technique proposed by Heath & Carter (1990). To assess physical activity level, we used the short version of the International Physical Activity Questionnaire (IPAQ). We used as health-related anthropometric indicators: body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), and conicity index (CI). We used descriptive statistics to characterize the sample, and then used a multivariate analysis of variance (a = 0.05) to test for differences. In the somatotype analysis, we observed among women significant predominance of the endomorphy and lower predominance of the ectomorphy in comparison to men. In the age group ≤ 29 years significantly lower values were found for endomorphy than in other age groups. Irregularly active individuals had significantly lower values of endomorphy. We observed that individuals with obesity and risk in WHR, WC and CI had higher scores of endomorphy and mesomorphy and lower scores of ectomorphy. The somatotype of physically active individuals in the present study raises health concern, mainly related to high relative adiposity represented by endomorphy.

  10. High-Throughput Analysis of Enzyme Activities

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Guoxin [Iowa State Univ., Ames, IA (United States)


    High-throughput screening (HTS) techniques have been applied to many research fields nowadays. Robot microarray printing technique and automation microtiter handling technique allows HTS performing in both heterogeneous and homogeneous formats, with minimal sample required for each assay element. In this dissertation, new HTS techniques for enzyme activity analysis were developed. First, patterns of immobilized enzyme on nylon screen were detected by multiplexed capillary system. The imaging resolution is limited by the outer diameter of the capillaries. In order to get finer images, capillaries with smaller outer diameters can be used to form the imaging probe. Application of capillary electrophoresis allows separation of the product from the substrate in the reaction mixture, so that the product doesn't have to have different optical properties with the substrate. UV absorption detection allows almost universal detection for organic molecules. Thus, no modifications of either the substrate or the product molecules are necessary. This technique has the potential to be used in screening of local distribution variations of specific bio-molecules in a tissue or in screening of multiple immobilized catalysts. Another high-throughput screening technique is developed by directly monitoring the light intensity of the immobilized-catalyst surface using a scientific charge-coupled device (CCD). Briefly, the surface of enzyme microarray is focused onto a scientific CCD using an objective lens. By carefully choosing the detection wavelength, generation of product on an enzyme spot can be seen by the CCD. Analyzing the light intensity change over time on an enzyme spot can give information of reaction rate. The same microarray can be used for many times. Thus, high-throughput kinetic studies of hundreds of catalytic reactions are made possible. At last, we studied the fluorescence emission spectra of ADP and obtained the detection limits for ADP under three different

  11. Application of neutron activation analysis to the study of impurities in molybdenum, tungsten and nuclear graphite; Application de l'analyse par activation neutronique a l'etude des impuretes dans le molybdene, le tungstene et le graphite nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Pinte, G. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires


    A neutron activation method is described for the analysis of a maximum number of foreign elements in molybdenum, tungsten and graphite. The various elements are isolated using a systematic separation programme; the elements are subsequently analysed qualitatively and quantitatively using {gamma}-spectrometry. By this method are dosed 27 elements in molybdenum and tungsten, and 20 elements in graphite to which can be added those elements which are already the object of routine analysis: V, Mn, Si, P, S, Cl and 14 rare earths. (author) [French] On decrit une methode d'analyse par activation neutronique permettant de doser un maximum d'elements etrangers dans le molybdene, le tungstene et le graphite. En suivant un schema de separation systematique, on isole les differents elements dont les analyses qualitatives et quantitatives sont ensuite effectuees par spectrometrie {gamma}. Par cette methode, on dose 27 elements dans le molybdene et le tungstene, 20 elements dans le graphite, auxquels on peut encore ajouter les elements doses couramment: V, Mn, Si, P, S, Cl et 14 Terres Rares. (auteur)

  12. Neutron activation analysis (NAA), radioisotope production via neutron activation (PNA) and fission product gas-jet (GJA)

    Energy Technology Data Exchange (ETDEWEB)

    Gaeggeler, H.W. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    Three different non-diffractive applications of neutrons are outlined, neutron activation analysis, production of radionuclides, mostly for medical applications, and production of short-lived fission nuclides with a so-called gas-jet. It is shown that all three devices may be incorporated into one single insert at SINQ due to their different requests with respect to thermal neutron flux. Some applications of these three facilities are summarized. (author) 3 figs., 1 tab., 8 refs.

  13. Codesign Analysis of a Computer Graphics Application

    DEFF Research Database (Denmark)

    Madsen, Jan; Brage, Jens P.


    This paper describes a codesign case study where a computer graphics application is examined with the intention to speed up its execution. The application is specified as a C program, and is characterized by the lack of a simple compute-intensive kernel. The hardware/software partitioning is based...

  14. Advanced Power Technology Development Activities for Small Satellite Applications (United States)

    Piszczor, Michael F.; Landis, Geoffrey A.; Miller, Thomas B.; Taylor, Linda M.; Hernandez-Lugo, Dionne; Raffaelle, Ryne; Landi, Brian; Hubbard, Seth; Schauerman, Christopher; Ganter, Mathew; hide


    NASA Glenn Research Center (GRC) has a long history related to the development of advanced power technology for space applications. This expertise covers the breadth of energy generation (photovoltaics, thermal energy conversion, etc.), energy storage (batteries, fuel cell technology, etc.), power management and distribution, and power systems architecture and analysis. Such advanced technology is now being developed for small satellite and cubesat applications and could have a significant impact on the longevity and capabilities of these missions. A presentation during the Pre-Conference Workshop will focus on various advanced power technologies being developed and demonstrated by NASA, and their possible application within the small satellite community.

  15. Physical Activity Recognition with Mobile Phones: Challenges, Methods, and Applications (United States)

    Yang, Jun; Lu, Hong; Liu, Zhigang; Boda, Péter Pál

    In this book chapter, we present a novel system that recognizes and records the physical activity of a person using a mobile phone. The sensor data is collected by built-in accelerometer sensor that measures the motion intensity of the device. The system recognizes five everyday activities in real-time, i.e., stationary, walking, running, bicycling, and in vehicle. We first introduce the sensor's data format, sensor calibration, signal projection, feature extraction, and selection methods. Then we have a detailed discussion and comparison of different choices of feature sets and classifiers. The design and implementation of one prototype system is presented along with resource and performance benchmark on Nokia N95 platform. Results show high recognition accuracies for distinguishing the five activities. The last part of the chapter introduces one demo application built on top of our system, physical activity diary, and a selection of potential applications in mobile wellness, mobile social sharing and contextual user interface domains.

  16. Activated carbon from leather shaving wastes and its application in removal of toxic materials. (United States)

    Kantarli, Ismail Cem; Yanik, Jale


    In this study, utilization of a solid waste as raw material for activated carbon production was investigated. For this purpose, activated carbons were produced from chromium and vegetable tanned leather shaving wastes by physical and chemical activation methods. A detailed analysis of the surface properties of the activated carbons including acidity, total surface area, extent of microporosity and mesoporosity was presented. The activated carbon produced from vegetable tanned leather shaving waste produced has a higher surface area and micropore volume than the activated carbon produced from chromium tanned leather shaving waste. The potential application of activated carbons obtained from vegetable tanned shavings as adsorbent for removal of water pollutants have been checked for phenol, methylene blue, and Cr(VI). Adsorption capacities of activated carbons were found to be comparable to that of activated carbons derived from biomass. 2010 Elsevier B.V. All rights reserved.

  17. Radio-analysis. Applications: biological dosimetry; Radioanalyse. Applications: dosage biologique

    Energy Technology Data Exchange (ETDEWEB)

    Bourrel, F. [CEA Saclay, INSTN, Institut National des Sciences et Techniques Nucleaires, 91 - Gif-sur-Yvette (France); Courriere, Ph. [UFR de Pharmacie, 31 - Toulouse (France)


    Radioisotopes have revolutionized the medical biology. Radio-immunology remains the reference measurement of the infinitely small in biology. Constant efforts have been performed to improve the simpleness, detectability and fastness of the method thanks to an increasing automation. This paper presents: 1 - the advantages of compounds labelling and the isotopic dilution; 2 - the antigen-antibody system: properties, determination of the affinity constant using the Scatchard method; 3 - radio-immunologic dosimetry: competitive dosimetry (radioimmunoassay), calibration curve and mathematical data processing, application to the free thyroxine dosimetry, immunoradiometric dosimetry (immunoradiometric assay), evaluation of the analytical efficiency of a radioimmunoassay; 4 - detection of the radioactive signal (solid and liquid scintillation). (J.S.)

  18. Particulate matter and neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Otoshi, Tsunehiko [Tohoku Univ. of Community Service and Science, Sakata, Yamagata (Japan)


    In these years, economy of East Asian region is rapidly growing, and countries in this region are facing serious environmental problems. Neutron activation analysis is known as one of high-sensitive analytical method for multi elements. And it is a useful tool for environmental research, particularly for the study on atmospheric particulate matter that consists of various constituents. Elemental concentration represents status of air, such as emission of heavy metals from industries and municipal incinerators, transportation of soil derived elements more than thousands of kilometers, and so on. These monitoring data obtained by neutron activation analysis can be a cue to evaluate environment problems. Japanese government launched National Air Surveillance Network (NASN) employing neutron activation analysis in 1974, and the data has been accumulated at about twenty sampling sites. As a result of mitigation measure of air pollution sources, concentrations of elements that have anthropogenic sources decreased particularly at the beginning of the monitoring period. However, even now, concentrations of these anthropogenic elements reflect the characteristics of each sampling site, e.g. industrial/urban, rural, and remote. Soil derived elements have a seasonal variation because of the contribution of continental dust transported by strong westerly winds prevailing in winter and spring season. The health effects associated with trace elements in particulate matter have not been well characterized. However, there is increasing evidence that particulate air pollution, especially fine portion of particles in many different cities is associated with acute mortality. Neutron activation analysis is also expected to provide useful information to this new study field related to human exposures and health risk. (author)

  19. Studies of activated carbon and carbon black for supercapacitor applications

    Energy Technology Data Exchange (ETDEWEB)

    Richner, R.; Mueller, S.; Koetz, R.; Wokaun, A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    Carbon Black and activated carbon materials providing high surface areas and a distinct pore distribution are prime materials for supercapacitor applications at frequencies < 0.5 Hz. A number of these materials were tested for their specific capacitance, surface and pore size distribution. High capacitance electrodes were manufactured on the laboratory scale with attention to ease of processability. (author) 1 fig., 1 ref.

  20. Design of an active array filtenna for radar applications

    NARCIS (Netherlands)

    Cifola, L.; Gerini, G.; Berg, S. van den; Water, F. van de


    A novel design of an S-band active array antenna with enhanced frequency selectivity properties, for radar applications, is presented. The array unit cell consists of a stacked-patch radiator, characterized by an operational bandwidth of [2.8 - 3.4] GHz. A microstrip two-pole band pass filter is

  1. Recent Research and Application Activities on Structural Health ...

    African Journals Online (AJOL)

    Developments and applications of Structural Health Monitoring (SHM) systems have become active particularly for long-span bridges in Korea. They are composed of sensors, data acquisition system, data transmission system, information processing, damage assessment, and information management. In this paper ...

  2. Causal Meta-Analysis : Methodology and Applications

    NARCIS (Netherlands)

    Bax, L.J.|info:eu-repo/dai/nl/304818577


    Meta-analysis is a statistical method to summarize research data from multiple studies in a quantitative manner. This dissertation addresses a number of methodological topics in causal meta-analysis and reports the development and validation of meta-analysis software. In the first (methodological)

  3. An Empirical Ultraviolet Iron Spectrum Template Applicable to Active Galaxies

    DEFF Research Database (Denmark)

    Vestergaard, Marianne; Wilkes, B. J.


    Iron emission is often a severe contaminant in optical-ultraviolet spectra of active galaxies. Its presence complicates emission line studies. A viable solution, already successfully applied at optical wavelengths, is to use an empirical iron emission template. We have generated FeII and Fe......III templates for ultraviolet active galaxy spectra based on HST archival 1100 - 3100 A spectra of IZw1. Their application allows fitting and subtraction of the iron emission in active galaxy spectra. This work has shown that in particular CIII] lambda 1909 can be heavily contaminated by other line emission...

  4. Applications of Digital Image Analysis in Experimental Mechanics


    Lyngbye, J. : Ph.D.


    The present thesis "Application of Digital Image Analysis in Experimental Mechanics" has been prepared as a part of Janus Lyngbyes Ph.D. study during the period December 1988 to June 1992 at the Department of Building technology and Structural Engineering, University of Aalborg, Denmark. In this thesis attention will be focused on optimal use and analysis of the information of digital images. This is realized during investigation and application of parametric methods in digital image analysis...

  5. Application of active packaging systems in probiotic foods

    Directory of Open Access Journals (Sweden)

    Renata Dobrucka


    Full Text Available Background: The packaging of the product has an important role in the protection of the stability of the final product. The use of active packaging system is due to play an increasingly important role by offering numerous and innovative solutions for extending the shelf-life or improve food quality and safety. Methods: On the basis of broad review of the current state of the art in world literature, application of packaging systems in probiotics foods was discussed. Results: In this study presented research and development in packaging systems for probiotics foods, using suitable materials with combine passive with active packaging solutions. Conclusion: Active packages with incorporated oxygen barrier materials or films with selective permeability properties also have potential applications in the packaging of probiotic food products. This is a broad field of research for scientists and industry.

  6. Time Series Analysis, Modeling and Applications A Computational Intelligence Perspective

    CERN Document Server

    Chen, Shyi-Ming


    Temporal and spatiotemporal data form an inherent fabric of the society as we are faced with streams of data coming from numerous sensors, data feeds, recordings associated with numerous areas of application embracing physical and human-generated phenomena (environmental data, financial markets, Internet activities, etc.). A quest for a thorough analysis, interpretation, modeling and prediction of time series comes with an ongoing challenge for developing models that are both accurate and user-friendly (interpretable). The volume is aimed to exploit the conceptual and algorithmic framework of Computational Intelligence (CI) to form a cohesive and comprehensive environment for building models of time series. The contributions covered in the volume are fully reflective of the wealth of the CI technologies by bringing together ideas, algorithms, and numeric studies, which convincingly demonstrate their relevance, maturity and visible usefulness. It reflects upon the truly remarkable diversity of methodological a...

  7. Biochar as potential sustainable precursors for activated carbon production: Multiple applications in environmental protection and energy storage. (United States)

    Tan, Xiao-Fei; Liu, Shao-Bo; Liu, Yun-Guo; Gu, Yan-Ling; Zeng, Guang-Ming; Hu, Xin-Jiang; Wang, Xin; Liu, Shao-Heng; Jiang, Lu-Hua


    There is a growing interest of the scientific community on production of activated carbon using biochar as potential sustainable precursors pyrolyzed from biomass wastes. Physical activation and chemical activation are the main methods applied in the activation process. These methods could have significantly beneficial effects on biochar chemical/physical properties, which make it suitable for multiple applications including water pollution treatment, CO 2 capture, and energy storage. The feedstock with different compositions, pyrolysis conditions and activation parameters of biochar have significant influences on the properties of resultant activated carbon. Compared with traditional activated carbon, activated biochar appears to be a new potential cost-effective and environmentally-friendly carbon materials with great application prospect in many fields. This review not only summarizes information from the current analysis of activated biochar and their multiple applications for further optimization and understanding, but also offers new directions for development of activated biochar. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. US Air Force fuel cell application analysis (United States)

    Pouchot, W. D.; Summers, W. A.; Hofbauer, J. A.


    Fuel Cell Power Unit conceptual designs and cost/benefit analyses were accomplished for six U.S. Air Force applications. The applications included two attended remote sites, two unattended remote sites and two tactical/mobile requirements. The electrical power ratings of these designs ranged from 23 kW to 100 kW. Fuels considered included diesel, Jet Fuel (JP-4) and methanol. Life cycle cost and benefit analyses showed that significant savings and operational improvements could be realized with the introduction of fuel cells into the USAF power generation inventory.

  9. Applications of social media and social network analysis

    CERN Document Server

    Kazienko, Przemyslaw


    This collection of contributed chapters demonstrates a wide range of applications within two overlapping research domains: social media analysis and social network analysis. Various methodologies were utilized in the twelve individual chapters including static, dynamic and real-time approaches to graph, textual and multimedia data analysis. The topics apply to reputation computation, emotion detection, topic evolution, rumor propagation, evaluation of textual opinions, friend ranking, analysis of public transportation networks, diffusion in dynamic networks, analysis of contributors to commun

  10. Activation analysis of ITER blanket first wall

    Energy Technology Data Exchange (ETDEWEB)

    Lopatkin, A.; Muratov, V. [RDIPE (NIKIET), Moscow (Russian Federation)


    To analyze the activation of ITER blanket structural components, the authors have prepared the AUCDAS code that calculates changes in nuclide concentrations and radioactivity characteristics during neutron irradiation and during cooling. UCDAS takes into account all neutron reactions and decay types, the prepared library of constants contains nuclear data of nuclides from hydrogen to californium. A comparative analysis of the results as obtained using UCDAS code and the widely known FISPACT code is given. The analysis of decay heat, gas generation and activity of ITER blanket first wall`s structural components was carried out. The beryllium coating, copper alloy and stainless steel were analysed. Calculations were performed for the first plasma burning pulse, 6 months and 1 year of operation in accordance with the ITER scenario. The materials recommended by ITER central team and their Russian analogs were considered: TGR and B1 (beryllium coating), GlidCop AL-25 Ds and Br-MKX (copper alloy), 316LN-IG and 12Cr18Ni10Ti (stainless steel). It has been demonstrated that there is a difference in all of the considered characteristics between the above materials. It is caused by impurities which are present in the materials. The report also considers the accumulation of gases (H, D, T, He{sup 3}, He{sup 4}) in the above materials. Besides, the change in the activity of irradiated materials during the cooling of up to 10{sup 7} years was calculated. (orig.) 7 refs.

  11. Regression Analysis: Legal Applications in Institutional Research (United States)

    Frizell, Julie A.; Shippen, Benjamin S., Jr.; Luna, Andrew L.


    This article reviews multiple regression analysis, describes how its results should be interpreted, and instructs institutional researchers on how to conduct such analyses using an example focused on faculty pay equity between men and women. The use of multiple regression analysis will be presented as a method with which to compare salaries of…

  12. Computer applications for engineering/structural analysis

    Energy Technology Data Exchange (ETDEWEB)

    Zaslawsky, M.; Samaddar, S.K.


    Analysts and organizations have a tendency to lock themselves into specific codes with the obvious consequences of not addressing the real problem and thus reaching the wrong conclusion. This paper discusses the role of the analyst in selecting computer codes. The participation and support of a computation division in modifying the source program, configuration management, and pre- and post-processing of codes are among the subjects discussed. Specific examples illustrating the computer code selection process are described in the following problem areas: soil structure interaction, structural analysis of nuclear reactors, analysis of waste tanks where fluid structure interaction is important, analysis of equipment, structure-structure interaction, analysis of the operation of the superconductor supercollider which includes friction and transient temperature, and 3D analysis of the 10-meter telescope being built in Hawaii. Validation and verification of computer codes and their impact on the selection process are also discussed.

  13. Space Telecommunications Radio System (STRS) Application Repository Design and Analysis (United States)

    Handler, Louis M.


    The Space Telecommunications Radio System (STRS) Application Repository Design and Analysis document describes the STRS application repository for software-defined radio (SDR) applications intended to be compliant to the STRS Architecture Standard. The document provides information about the submission of artifacts to the STRS application repository, to provide information to the potential users of that information, and for the systems engineer to understand the requirements, concepts, and approach to the STRS application repository. The STRS application repository is intended to capture knowledge, documents, and other artifacts for each waveform application or other application outside of its project so that when the project ends, the knowledge is retained. The document describes the transmission of technology from mission to mission capturing lessons learned that are used for continuous improvement across projects and supporting NASA Procedural Requirements (NPRs) for performing software engineering projects and NASAs release process.

  14. Applications of Digital Image Analysis in Experimental Mechanics

    DEFF Research Database (Denmark)

    Lyngbye, J. : Ph.D.

    The present thesis "Application of Digital Image Analysis in Experimental Mechanics" has been prepared as a part of Janus Lyngbyes Ph.D. study during the period December 1988 to June 1992 at the Department of Building technology and Structural Engineering, University of Aalborg, Denmark....... In this thesis attention will be focused on optimal use and analysis of the information of digital images. This is realized during investigation and application of parametric methods in digital image analysis. The parametric methods will be implemented in applications representative for the area of experimental...

  15. Computational intelligence for big data analysis frontier advances and applications

    CERN Document Server

    Dehuri, Satchidananda; Sanyal, Sugata


    The work presented in this book is a combination of theoretical advancements of big data analysis, cloud computing, and their potential applications in scientific computing. The theoretical advancements are supported with illustrative examples and its applications in handling real life problems. The applications are mostly undertaken from real life situations. The book discusses major issues pertaining to big data analysis using computational intelligence techniques and some issues of cloud computing. An elaborate bibliography is provided at the end of each chapter. The material in this book includes concepts, figures, graphs, and tables to guide researchers in the area of big data analysis and cloud computing.

  16. Various Applications of Power Spectrum Analysis (PSA) (United States)


    ications: pro ckaging, and ower Spectru kage; Gamma analysis (P in responses d to dynam in the power s gnatures are fo IC. PSA ha rences betwee...on a d op plot in F re (top black connected to a shown in the m voltage is c rtion in the vo Applicat Paiboo Valid Sandia Na Analysis (P tion...tool. We cess monitor changes due m Analysis ; -ray Exposure SA) measures of an integrat ic stimuli. pectrum associ und to be sen s been an ef n

  17. Design and Application of the Exploration Maintainability Analysis Tool (United States)

    Stromgren, Chel; Terry, Michelle; Crillo, William; Goodliff, Kandyce; Maxwell, Andrew


    Conducting human exploration missions beyond Low Earth Orbit (LEO) will present unique challenges in the areas of supportability and maintainability. The durations of proposed missions can be relatively long and re-supply of logistics, including maintenance and repair items, will be limited or non-existent. In addition, mass and volume constraints in the transportation system will limit the total amount of logistics that can be flown along with the crew. These constraints will require that new strategies be developed with regards to how spacecraft systems are designed and maintained. NASA is currently developing Design Reference Missions (DRMs) as an initial step in defining future human missions. These DRMs establish destinations and concepts of operation for future missions, and begin to define technology and capability requirements. Because of the unique supportability challenges, historical supportability data and models are not directly applicable for establishing requirements for beyond LEO missions. However, supportability requirements could have a major impact on the development of the DRMs. The mass, volume, and crew resources required to support the mission could all be first order drivers in the design of missions, elements, and operations. Therefore, there is a need for enhanced analysis capabilities to more accurately establish mass, volume, and time requirements for supporting beyond LEO missions. Additionally, as new technologies and operations are proposed to reduce these requirements, it is necessary to have accurate tools to evaluate the efficacy of those approaches. In order to improve the analysis of supportability requirements for beyond LEO missions, the Space Missions Analysis Branch at the NASA Langley Research Center is developing the Exploration Maintainability Analysis Tool (EMAT). This tool is a probabilistic simulator that evaluates the need for repair and maintenance activities during space missions and the logistics and crew

  18. Computational Models for Analysis of Illicit Activities

    DEFF Research Database (Denmark)

    Nizamani, Sarwat

    . These models include a model for analyzing evolution of terrorist networks; a text classification model for detecting suspicious text and identification of suspected authors of anonymous emails; and a semantic analysis model for news reports, which may help analyze the illicit activities in certain area...... traditional models for both of the tasks. Apart from these globally organized crimes and cybercrimes, there happen specific world issues which affect geographic locations and take the form of bursts of public violence. These kinds of issues have received little attention by the academicians. These issues have...

  19. Analysis of Embedded Applications By Evolutionary Fuzzing


    Alimi, Vincent; Vernois, Sylvain; Rosenberger, Christophe


    International audience; In this paper, we propose to use fuzzing techniques to discover vulnerabilities in programs hosted into smart cards used for telecommunications or banking purposes (SIM cards, credit cards, secure element into NFC mobile devices. . . ). Those programs - called applets - usually host sensitive applications and manipulate sensitive data. A flaw by design or by implementation in one of those applet could have disastrous consequences. The proposed approach uses a genetic al...

  20. Statistical shape analysis with applications in R

    CERN Document Server

    Dryden, Ian L


    A thoroughly revised and updated edition of this introduction to modern statistical methods for shape analysis Shape analysis is an important tool in the many disciplines where objects are compared using geometrical features. Examples include comparing brain shape in schizophrenia; investigating protein molecules in bioinformatics; and describing growth of organisms in biology. This book is a significant update of the highly-regarded `Statistical Shape Analysis’ by the same authors. The new edition lays the foundations of landmark shape analysis, including geometrical concepts and statistical techniques, and extends to include analysis of curves, surfaces, images and other types of object data. Key definitions and concepts are discussed throughout, and the relative merits of different approaches are presented. The authors have included substantial new material on recent statistical developments and offer numerous examples throughout the text. Concepts are introduced in an accessible manner, while reta...

  1. Applications of decision analysis in diagnostic radiology

    NARCIS (Netherlands)

    M.G.M. Hunink (Myriam)


    textabstractThe subjects of this thesis are decision analysis and receiver operating characteristic (ROC) methodology applied to radiological problems. This thesis is intended for those interested in applying decision analytical techniques in diagnostic radiology, and in medicine in

  2. Application of karyotype analysis in radiation hygiene

    Energy Technology Data Exchange (ETDEWEB)

    Stojkovic, J. (Krajska Hygienicka Stanica, Bratislava (Czechoslovakia))


    Case studies are presented in which an analysis was used of the karyotype of peripheral blood lymphocytes. The results are also given of long-term monitoring of the karyotype in a group of employees of a nuclear power plant.

  3. Analysis of queues methods and applications

    CERN Document Server

    Gautam, Natarajan


    Introduction Analysis of Queues: Where, What, and How?Systems Analysis: Key ResultsQueueing Fundamentals and Notations Psychology in Queueing Reference Notes Exercises Exponential Interarrival and Service Times: Closed-Form Expressions Solving Balance Equations via Arc CutsSolving Balance Equations Using Generating Functions Solving Balance Equations Using Reversibility Reference Notes ExercisesExponential Interarrival and Service Times: Numerical Techniques and Approximations Multidimensional Birth and Death ChainsMultidimensional Markov Chains Finite-State Markov ChainsReference Notes Exerci

  4. A Versatile Active Block: DXCCCII and Tunable Applications

    Directory of Open Access Journals (Sweden)

    S. A. Tekin


    Full Text Available The study describes dual-X controlled current conveyor (DXCCCII as a versatile active block and its application to inductance simulators for testing. Moreover, the high pass filter application using with DXCCCII based inductance simulator and oscillator with flexible tunable oscillation frequency have been presented and simulated to confirm the theoretical validity. The proposed circuit which has a simple circuit design requires the low-voltage and the DXCCCII can also be tuned in the wide range by the biasing current. The proposed DXCCCII provides a good linearity, high output impedance at Z terminals, and a reasonable current and voltage transfer gain accuracy. The proposed DXCCCII and its applications have been simulated using the CMOS 0.18 µm technology.

  5. Application of tooth brushing behavior to active rest. (United States)

    Sadachi, Hidetoshi; Murakami, Yoshinori; Tonomura, Manabu; Yada, Yukihiro; Simoyama, Ichiro


    We evaluated the usefulness of tooth brushing with toothpaste as active rest using the flicker value as a physiological parameter and a subjective questionnaire as a psychological parameter. Seventeen healthy, right-handed subjects (12 males and 5 females) aged 22.5 +/- 1.5 yr (mean +/- standard deviation) were randomly divided into tooth brushing with toothpaste (N=9) and non-tooth brushing groups (N=8). The subjects performed a serial calculation task for 20 min using personal computers. Subsequently, the tooth brushing group brushed their teeth, and the flicker value and mood were compared before and after the tooth brushing. The flicker value significantly increased in the tooth brushing group compared with the non-tooth brushing group (pbrushing group, the incidence of a "feeling of being refreshed" significantly increased (pbrushing activated cerebral activity, producing refreshing effects. These results suggest the applicability of tooth brushing to active rest.

  6. Neutron activation analysis and atomic absorption spectrophotometry for the analysis of fresh, pasteurised and powder milk

    Energy Technology Data Exchange (ETDEWEB)

    Wasim, M.; Rehman, S.; Arif, M.; Fatima, I.; Zaidi, J.H. [Pakistan Inst. of Nuclear Science and Technology, Islamabad (Pakistan). Chemistry Div.


    This study shows the application of semi-absolute k{sub 0} instrumental neutron activation analysis (k{sub 0}-INAA), epithermal neutron activation analysis (ENAA) and atomic absorption spectrophotometry (AAS) for the determination of 21 elements (Br, Ca, Cl, Co, Cr, Cs, Cu, Fe, Hf, I, K, Mg, Mn, Na, Ni, P, Pb, Rb, Sc Sr, and Zn) in different types of milk samples. The ENAA was required for the determination of iodine, AAS for Cu, Ni and Pb and the rest of the elements were measured by k{sub 0}-INAA. Thirteen elements (Br, Ca, Cl, Cs, Cu, Fe, K, Mg, Na, P, Rb, Sr and Zn) were identified in all milk samples. Ni was detected in eleven and Pb in two samples. Concentrations of most of the elements were within the ranges of the world reported data. The data was further explored by principal component analysis to find relationships between samples and elements. (orig.)

  7. Cross-impacts analysis development and energy policy analysis applications

    Energy Technology Data Exchange (ETDEWEB)

    Roop, J.M.; Scheer, R.M.; Stacey, G.S.


    Purpose of this report is to describe the cross-impact analysis process and microcomputer software developed for the Office of Policy, Planning, and Analysis (PPA) of DOE. First introduced in 1968, cross-impact analysis is a technique that produces scenarios of future conditions and possibilities. Cross-impact analysis has several unique attributes that make it a tool worth examining, especially in the current climate when the outlook for the economy and several of the key energy markets is uncertain. Cross-impact analysis complements the econometric, engineering, systems dynamics, or trend approaches already in use at DOE. Cross-impact analysis produces self-consistent scenarios in the broadest sense and can include interaction between the economy, technology, society and the environment. Energy policy analyses that couple broad scenarios of the future with detailed forecasting can produce more powerful results than scenario analysis or forecasts can produce alone.

  8. Very Compact and Broadband Active Antenna for VHF Band Applications

    Directory of Open Access Journals (Sweden)

    Y. Taachouche


    Full Text Available An active receiving antenna with small size consisting of a monopole loaded with a transistor bipolar is presented in this paper. A transistor is used in order to miniaturize the receiving active antenna size in VHF band. The vertical size of the structure is equal to λ/175, where λ is the wavelength at the lower frequency of the bandwidth. Despite the very small size of the antenna, the frequency bandwidth is very wide and the gain is suitable for FM application with sensitive receivers.

  9. Cellulose Electro-Active Paper: From Discovery to Technology Applications (United States)

    Abas, Zafar; Kim, Heung Soo; Kim, Jaehwan; Kim, Joo-Hyung


    Cellulose electro-active paper (EAPap) is an attractive material of electro-active polymers (EAPs) family due to its smart characteristics. EAPap is thin cellulose film coated with metal electrodes on both sides. Its large displacement output, low actuation voltage and low power consumption can be used for biomimetic sensors/actuators and electromechanical system. Because cellulose EAPap is ultra-lightweight, easy to manufacture, inexpensive, biocompatible, and biodegradable, it has been employed for many applications such as bending actuator, vibration sensor, artificial muscle, flexible speaker, and can be advantageous in areas such as micro-insect robots, micro-flying objects, microelectromechanical systems, biosensors, and flexible displays.

  10. Modeling & imaging of bioelectrical activity principles and applications

    CERN Document Server

    He, Bin


    Over the past several decades, much progress has been made in understanding the mechanisms of electrical activity in biological tissues and systems, and for developing non-invasive functional imaging technologies to aid clinical diagnosis of dysfunction in the human body. The book will provide full basic coverage of the fundamentals of modeling of electrical activity in various human organs, such as heart and brain. It will include details of bioelectromagnetic measurements and source imaging technologies, as well as biomedical applications. The book will review the latest trends in



    Rosencwaig, A.


    Nonspectroscopic applications of thermal-wave physics, in particular those involving materials analysis through thermal-wave imaging, and quantitative thin-film thickness measurements, are described for the study of semiconductor materials and devices.

  12. Application of Image Analysis in Optical Microscopy of Ordinary Chondrites (United States)

    Petrova, E. V.; Petrov, M. S.; Grokhovsky, V. I.


    Application of image analysis systems give additional possibilities for estimation, calculation and comparison of optical microscopic images. Different parameters of the texture (phase distribution, porosity, grains shape parameters) can be obtained.

  13. Active Integrated Antennas for Sensor and Communication Applications


    Kaleja, Martin


    Active integrated antennas are used for frequency generation and the radiation of millimeter-waves. Due to their compactness and low-cost fabrication, they are suited for different sensor and communication applications. Modeling these antennas is a difficult task due to the com-bination of antenna and oscillator properties. This thesis presents modeling approaches for different antenna concepts that significantly ease the design process while maintaining design accuracy. The validity of these...

  14. Dance Dynamics. Laban Movement Analysis: Theory and Application. (United States)

    Schwartz, Peggy; And Others


    Several articles provide a theoretical overview of the Laban Movement Analysis (LMA) and describe its application. Rudolf Laban's work has many applications relevant to dance, physical education, recreation, and movement education. LMA involves training and refining how one perceives movement. It can help educators better understand students from…

  15. An easy path to convex analysis and applications

    CERN Document Server

    Mordukhovich, Boris S


    Convex optimization has an increasing impact on many areas of mathematics, applied sciences, and practical applications. It is now being taught at many universities and being used by researchers of different fields. As convex analysis is the mathematical foundation for convex optimization, having deep knowledge of convex analysis helps students and researchers apply its tools more effectively. The main goal of this book is to provide an easy access to the most fundamental parts of convex analysis and its applications to optimization. Modern techniques of variational analysis are employed to cl

  16. Applications of model theory to functional analysis

    CERN Document Server

    Iovino, Jose


    During the last two decades, methods that originated within mathematical logic have exhibited powerful applications to Banach space theory, particularly set theory and model theory. This volume constitutes the first self-contained introduction to techniques of model theory in Banach space theory. The area of research has grown rapidly since this monograph's first appearance, but much of this material is still not readily available elsewhere. For instance, this volume offers a unified presentation of Krivine's theorem and the Krivine-Maurey theorem on stable Banach spaces, with emphasis on the

  17. Fundamentals of matrix analysis with applications

    CERN Document Server

    Saff, Edward Barry


    This book provides comprehensive coverage of matrix theory from a geometric and physical perspective, and the authors address the functionality of matrices and their ability to illustrate and aid in many practical applications.  Readers are introduced to inverses and eigenvalues through physical examples such as rotations, reflections, and projections, and only then are computational details described and explored.  MATLAB is utilized to aid in reader comprehension, and the authors are careful to address the issue of rank fragility so readers are not flummoxed when MATLAB displays conflict wit

  18. Feasibility of a mobile phone application to promote physical activity in cancer survivors

    Directory of Open Access Journals (Sweden)

    Anna Roberts


    Full Text Available Background: Regular participation in physical activity is associated with improved physical and psychosocial outcomes in cancer survivors. However, physical activity levels are low during and after cancer treatment. Interventions to promote physical activity in this population are needed. Mobile technology has potential, but currently, there is no mobile phone application designed to promote physical activity in cancer survivors. Objectives: The first aim is to assess feasibility and acceptability of an existing physical activity mobile application (‘app’ designed for the general population, in a sample of breast, colorectal and prostate cancer survivors. A further aim is to understand how the application could be adapted to overcome barriers to physical activity participation in this population. Methods: A feasibility study was carried out that investigated acceptability of and participants’ opinions on the application. A total of 11 cancer survivors tested the application for 6 weeks. Physical activity (Godin Leisure Time Exercise Questionnaire, wellbeing (FACT-G, fatigue (FACIT-Fatigue scale, quality of life (EQ5D, sleep quality (Pittsburgh Sleep Quality Index, anxiety and depression (Hospital Anxiety and Depression Scale were self-reported at baseline and at 6-week follow-up. Participants completed qualitative telephone interviews about their experiences of using the app, and these were coded using thematic analysis. Results: The application was acceptable among the participants; 73% of people who responded to the study advertisement agreed to participate, and 100% of participants who started the study completed. There was a significant increase in participants’ mean strenuous physical activity of 51.91 minutes per week from baseline to 6-week follow-up (P=0.005. There was also a significant reduction in reported sleep problems from baseline (mean=9.27, SD=6.72 to 6-week follow-up (mean=6.72, SD=5.50; P=0.01. There were no other

  19. Advances in Nonnegative Matrix Decomposition with Application to Cluster Analysis


    Zhang, He


    Nonnegative Matrix Factorization (NMF) has found a wide variety of applications in machine learning and data mining. NMF seeks to approximate a nonnegative data matrix by a product of several low-rank factorizing matrices, some of which are constrained to be nonnegative. Such additive nature often results in parts-based representation of the data, which is a desired property especially for cluster analysis.  This thesis presents advances in NMF with application in cluster analysis. It rev...

  20. Cost analysis of energy storage systems for electric utility applications

    Energy Technology Data Exchange (ETDEWEB)

    Akhil, A. [Sandia National Lab., Albuquerque, NM (United States); Swaminathan, S.; Sen, R.K. [R.K. Sen & Associates, Inc., Bethesda, MD (United States)


    Under the sponsorship of the Department of Energy, Office of Utility Technologies, the Energy Storage System Analysis and Development Department at Sandia National Laboratories (SNL) conducted a cost analysis of energy storage systems for electric utility applications. The scope of the study included the analysis of costs for existing and planned battery, SMES, and flywheel energy storage systems. The analysis also identified the potential for cost reduction of key components.

  1. Applications of Parallelism to Current Algorithms for Intelligence Analysis (United States)


    ALGORITHMS FOR INTELLIGENCE ANALYSIS Martha Ann Griesel * J. Steven Hughes Beth R. Moore 10 July 1987 National Aeronautics and Space Administration...INTELLIGENCE CENTER AND SCHOOL Software Analysis and Management System Applications of Parallelism to Current Algorithms for Intelligence Analysis 10 July 1987...rates and a growing diversity of IEW information sources create a void in current intelligence analysis methods. New ways are needed to quickly

  2. Uncooled LWIR imaging: applications and market analysis (United States)

    Takasawa, Satomi


    The evolution of infrared (IR) imaging sensor technology for defense market has played an important role in developing commercial market, as dual use of the technology has expanded. In particular, technologies of both reduction in pixel pitch and vacuum package have drastically evolved in the area of uncooled Long-Wave IR (LWIR; 8-14 μm wavelength region) imaging sensor, increasing opportunity to create new applications. From the macroscopic point of view, the uncooled LWIR imaging market is divided into two areas. One is a high-end market where uncooled LWIR imaging sensor with sensitivity as close to that of cooled one as possible is required, while the other is a low-end market which is promoted by miniaturization and reduction in price. Especially, in the latter case, approaches towards consumer market have recently appeared, such as applications of uncooled LWIR imaging sensors to night visions for automobiles and smart phones. The appearance of such a kind of commodity surely changes existing business models. Further technological innovation is necessary for creating consumer market, and there will be a room for other companies treating components and materials such as lens materials and getter materials and so on to enter into the consumer market.


    Directory of Open Access Journals (Sweden)



    Full Text Available The accuracy of numerical solution for electromagnetic problem is greatly influenced by the convergence of the solution obtained. In order to quantify the correctness of the numerical solution the errors produced on solving the partial differential equations are required to be analyzed. Mesh quality is another parameter that affects convergence. The various quality metrics are dependent on the type of solver used for numerical simulation. The paper focuses on comparing the performance of iterative solvers used in COMSOL Multiphysics software. The modeling of coaxial coupled waveguide applicator operating at 485MHz has been done for local hyperthermia applications using adaptive finite element method. 3D heat distribution within the muscle phantom depicting spherical leison and localized heating pattern confirms the proper selection of the solver. The convergence plots are obtained during simulation of the problem using GMRES (generalized minimal residual and geometric multigrid linear iterative solvers. The best error convergence is achieved by using nonlinearity multigrid solver and further introducing adaptivity in nonlinear solver.

  4. Computable Analysis with Applications to Dynamic Systems

    NARCIS (Netherlands)

    P.J. Collins (Pieter)


    htmlabstractIn this article we develop a theory of computation for continuous mathematics. The theory is based on earlier developments of computable analysis, especially that of the school of Weihrauch, and is presented as a model of intuitionistic type theory. Every effort has been made to keep the

  5. Introduction to Latent Class Analysis with Applications (United States)

    Porcu, Mariano; Giambona, Francesca


    Latent class analysis (LCA) is a statistical method used to group individuals (cases, units) into classes (categories) of an unobserved (latent) variable on the basis of the responses made on a set of nominal, ordinal, or continuous observed variables. In this article, we introduce LCA in order to demonstrate its usefulness to early adolescence…

  6. Identification of active constraints in dynamic flux balance analysis. (United States)

    Nikdel, Ali; Budman, Hector


    This study deals with the calibration of dynamic metabolic flux models that are formulated as the maximization of an objective subject to constraints. Two approaches were applied for identifying the constraints from data. In the first approach a minimal active number of limiting constraints is found based on data that are assumed to be bounded within sets whereas, in the second approach, the limiting constraints are found based on parametric sensitivity analysis. The ability of these approaches to finding the active limiting constraints was verified through their application to two case studies: an in-silico (simulated) data-based study describing the growth of E. coli and an experimental data-based study for Bordetella pertussis (B. pertussis). © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 33:26-36, 2017. © 2016 American Institute of Chemical Engineers.

  7. Analysis of phenolic compounds in different parts of pomegranate (Punica granatum) fruit by HPLC-PDA-ESI/MS and evaluation of their antioxidant activity: application to different Italian varieties. (United States)

    Russo, Marina; Fanali, Chiara; Tripodo, Giusy; Dugo, Paola; Muleo, Rosario; Dugo, Laura; De Gara, Laura; Mondello, Luigi


    The analysis of pomegranate phenolic compounds belonging to different classes in different fruit parts was performed by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detection. Two different separation methods were optimized for the analysis of anthocyanins and hydrolyzable tannins along with phenolic acids and flavonoids. Two C18 columns, core-shell and fully porous particle stationary phases, were used. The parameters for separation of phenolic compounds were optimized considering chromatographic resolution and analysis time. Thirty-five phenolic compounds were found, and 28 of them were tentatively identified as belonging to four different phenolic compound classes; namely, anthocyanins, phenolic acids, hydrolyzable tannins, and flavonoids. Quantitative analysis was performed with a mixture of nine phenolic compounds belonging to phenolic compound classes representative of pomegranate. The method was then fully validated in terms of retention time precision, expressed as the relative standard deviation, limit of detection, limit of quantification, and linearity range. Phenolic compounds were analyzed directly in pomegranate juice, and after solvent extraction with a mixture of water and methanol with a small percentage of acid in peel and pulp samples. The accuracy of the extraction method was also assessed, and satisfactory values were obtained. Finally, the method was used to study identified analytes in pomegranate juice, peel, and pulp of six different Italian varieties and one international variety. Differences in phenolic compound profiles among the different pomegranate parts were observed. Pomegranate peel samples showed a high concentration of phenolic compounds, ellagitannins being the most abundant ones, with respect to pulp and juice samples for each variety. With the same samples, total phenols and antioxidant activity were evaluated through colorimetric assays, and the results were correlated among them.

  8. Handbook of Time Series Analysis Recent Theoretical Developments and Applications

    CERN Document Server

    Schelter, Björn; Timmer, Jens


    This handbook provides an up-to-date survey of current research topics and applications of time series analysis methods written by leading experts in their fields. It covers recent developments in univariate as well as bivariate and multivariate time series analysis techniques ranging from physics' to life sciences' applications. Each chapter comprises both methodological aspects and applications to real world complex systems, such as the human brain or Earth's climate. Covering an exceptionally broad spectrum of topics, beginners, experts and practitioners who seek to understand the latest de

  9. Applications of decision analysis in diagnostic radiology


    Hunink, Myriam


    textabstractThe subjects of this thesis are decision analysis and receiver operating characteristic (ROC) methodology applied to radiological problems. This thesis is intended for those interested in applying decision analytical techniques in diagnostic radiology, and in medicine in general. Chapter II deals with the theory of decision trees and Markov processes. The basic concepts are briefly explained and a few selected topics are discussed in more detaiL Chapter III describes a decision mo...

  10. Malware Instrumentation Application to Regin Analysis


    Matthieu Kaczmarek


    The complexity of the Regin malware underlines the importance of reverse engineering in modern incident response. The present study shows that such complexity can be overcome: substantial information about adversary tactics, techniques and procedures is obtained from reverse engineering. An introduction to the Regin development framework is provided along with instrumentation guidelines. Such instrumentation enables experimentation with malware modules. So analysis can derectly leverage m...

  11. Towards sentiment analysis application in housing projects (United States)

    Mahadzir, Nurul Husna; Omar, Mohd Faizal; Nawi, Mohd Nasrun Mohd


    In becoming a develop nation by 2020, Malaysia Government realized the need in providing affordable house to the public. Since Second Malaysia Plan, government has implemented various affordable housing projects and it continues until recent Malaysia Plan. To measure the effectiveness of the initiatives taken, public opinion is necessary. A social media platform has been seen as the most effective mechanism to get information on people's thought and feeling towards certain issues. One of the best ways to extract emotions and thoughts from what people post in social media is through Sentiment Analysis (SA). There are three different levels of analysis: document level, sentence level and feature level. Most of previous research focused on the classification of sentiment at document or sentence level. Unfortunately, both document and sentence level does not discover what exactly people like or not. While the analysis based on feature, there exist accuracy problem when classifying the sentiment scores. This paper will propose a new framework that focuses on sentiment classification scores at feature level to overcome the uncertainty and accuracy issues on the result.

  12. Usability engineering: domain analysis activities for augmented-reality systems (United States)

    Gabbard, Joseph; Swan, J. E., II; Hix, Deborah; Lanzagorta, Marco O.; Livingston, Mark; Brown, Dennis B.; Julier, Simon J.


    This paper discusses our usability engineering process for the Battlefield Augmented Reality System (BARS). Usability engineering is a structured, iterative, stepwise development process. Like the related disciplines of software and systems engineering, usability engineering is a combination of management principals and techniques, formal and semi- formal evaluation techniques, and computerized tools. BARS is an outdoor augmented reality system that displays heads- up battlefield intelligence information to a dismounted warrior. The paper discusses our general usability engineering process. We originally developed the process in the context of virtual reality applications, but in this work we are adapting the procedures to an augmented reality system. The focus of this paper is our work on domain analysis, the first activity of the usability engineering process. We describe our plans for and our progress to date on our domain analysis for BARS. We give results in terms of a specific urban battlefield use case we have designed.

  13. Mobile Health Applications to Promote Active and Healthy Ageing. (United States)

    Helbostad, Jorunn L; Vereijken, Beatrix; Becker, Clemens; Todd, Chris; Taraldsen, Kristin; Pijnappels, Mirjam; Aminian, Kamiar; Mellone, Sabato


    The European population is ageing, and there is a need for health solutions that keep older adults independent longer. With increasing access to mobile technology, such as smartphones and smartwatches, the development and use of mobile health applications is rapidly growing. To meet the societal challenge of changing demography, mobile health solutions are warranted that support older adults to stay healthy and active and that can prevent or delay functional decline. This paper reviews the literature on mobile technology, in particular wearable technology, such as smartphones, smartwatches, and wristbands, presenting new ideas on how this technology can be used to encourage an active lifestyle, and discusses the way forward in order further to advance development and practice in the field of mobile technology for active, healthy ageing.

  14. Application of multidisciplinary analysis to gene expression.

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Xuefel (University of New Mexico, Albuquerque, NM); Kang, Huining (University of New Mexico, Albuquerque, NM); Fields, Chris (New Mexico State University, Las Cruces, NM); Cowie, Jim R. (New Mexico State University, Las Cruces, NM); Davidson, George S.; Haaland, David Michael; Sibirtsev, Valeriy (New Mexico State University, Las Cruces, NM); Mosquera-Caro, Monica P. (University of New Mexico, Albuquerque, NM); Xu, Yuexian (University of New Mexico, Albuquerque, NM); Martin, Shawn Bryan; Helman, Paul (University of New Mexico, Albuquerque, NM); Andries, Erik (University of New Mexico, Albuquerque, NM); Ar, Kerem (University of New Mexico, Albuquerque, NM); Potter, Jeffrey (University of New Mexico, Albuquerque, NM); Willman, Cheryl L. (University of New Mexico, Albuquerque, NM); Murphy, Maurice H. (University of New Mexico, Albuquerque, NM)


    Molecular analysis of cancer, at the genomic level, could lead to individualized patient diagnostics and treatments. The developments to follow will signal a significant paradigm shift in the clinical management of human cancer. Despite our initial hopes, however, it seems that simple analysis of microarray data cannot elucidate clinically significant gene functions and mechanisms. Extracting biological information from microarray data requires a complicated path involving multidisciplinary teams of biomedical researchers, computer scientists, mathematicians, statisticians, and computational linguists. The integration of the diverse outputs of each team is the limiting factor in the progress to discover candidate genes and pathways associated with the molecular biology of cancer. Specifically, one must deal with sets of significant genes identified by each method and extract whatever useful information may be found by comparing these different gene lists. Here we present our experience with such comparisons, and share methods developed in the analysis of an infant leukemia cohort studied on Affymetrix HG-U95A arrays. In particular, spatial gene clustering, hyper-dimensional projections, and computational linguistics were used to compare different gene lists. In spatial gene clustering, different gene lists are grouped together and visualized on a three-dimensional expression map, where genes with similar expressions are co-located. In another approach, projections from gene expression space onto a sphere clarify how groups of genes can jointly have more predictive power than groups of individually selected genes. Finally, online literature is automatically rearranged to present information about genes common to multiple groups, or to contrast the differences between the lists. The combination of these methods has improved our understanding of infant leukemia. While the complicated reality of the biology dashed our initial, optimistic hopes for simple answers from

  15. Measurements and analysis in imaging for biomedical applications (United States)

    Hoeller, Timothy L.


    A Total Quality Management (TQM) approach can be used to analyze data from biomedical optical and imaging platforms of tissues. A shift from individuals to teams, partnerships, and total participation are necessary from health care groups for improved prognostics using measurement analysis. Proprietary measurement analysis software is available for calibrated, pixel-to-pixel measurements of angles and distances in digital images. Feature size, count, and color are determinable on an absolute and comparative basis. Although changes in images of histomics are based on complex and numerous factors, the variation of changes in imaging analysis to correlations of time, extent, and progression of illness can be derived. Statistical methods are preferred. Applications of the proprietary measurement software are available for any imaging platform. Quantification of results provides improved categorization of illness towards better health. As health care practitioners try to use quantified measurement data for patient diagnosis, the techniques reported can be used to track and isolate causes better. Comparisons, norms, and trends are available from processing of measurement data which is obtained easily and quickly from Scientific Software and methods. Example results for the class actions of Preventative and Corrective Care in Ophthalmology and Dermatology, respectively, are provided. Improved and quantified diagnosis can lead to better health and lower costs associated with health care. Systems support improvements towards Lean and Six Sigma affecting all branches of biology and medicine. As an example for use of statistics, the major types of variation involving a study of Bone Mineral Density (BMD) are examined. Typically, special causes in medicine relate to illness and activities; whereas, common causes are known to be associated with gender, race, size, and genetic make-up. Such a strategy of Continuous Process Improvement (CPI) involves comparison of patient results

  16. Hand geometry field application data analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ruehle, M.; Ahrens, J. [Sandia National Labs., Albuquerque, NM (United States). Entry Control/Systems Engineering Dept.


    Over the last fifteen years, Sandia National Laboratories Security Systems and Technology Center, Department 5800, has been involved in several laboratory tests of various biometric identification devices. These laboratory tests were conducted to verify the manufacturer`s performance claims, to determine strengths and weaknesses of particular devices, and to evaluate which devices meet the US Department of Energy`s unique needs for high-security devices. However, during a recent field installation of one of these devices, significantly different performance was observed than had been predicted by these laboratory tests. This report documents the data analysis performed in the search for an explanation of these differences.

  17. Meta-Analysis: Application to Clinical Dentistry and Dental Education. (United States)

    Cohen, Peter A.


    Meta-analysis is proposed as an effective alternative to conventional narrative review for extracting trends from research findings. This type of analysis is explained, advantages over more traditional review techniques are discussed, basic procedures and limitations are outlined, and potential applications in dental education and clinical…

  18. Application of automatic image analysis in wood science (United States)

    Charles W. McMillin


    In this paper I describe an image analysis system and illustrate with examples the application of automatic quantitative measurement to wood science. Automatic image analysis, a powerful and relatively new technology, uses optical, video, electronic, and computer components to rapidly derive information from images with minimal operator interaction. Such instruments...

  19. Hands on applied finite element analysis application with ANSYS

    CERN Document Server

    Arslan, Mehmet Ali


    Hands on Applied Finite Element Analysis Application with Ansys is truly an extraordinary book that offers practical ways of tackling FEA problems in machine design and analysis. In this book, 35 good selection of example problems have been presented, offering students the opportunity to apply their knowledge to real engineering FEA problem solutions by guiding them with real life hands on experience.

  20. Nodal Discontinuous Element Methods: Formulations, Analysis, and Applications

    DEFF Research Database (Denmark)

    Hesthaven, Jan

    Part of concluding summary and outlook: "The focus of this thesis has been on the formulation, analysis, and application of high-order accurate computational techniques for solving rather general initial boundary value problems, emphasizing an analysis driven theoretical foundation. As such...


    Directory of Open Access Journals (Sweden)

    Alfa Firdaus


    Full Text Available Energy audit is one of the first tasks to be performed in the accomplishment of an effective energy cost control program. To obtain the best information for a successful energy audit, the auditor must make some measurements during the audit visit. One of the tools that primarily used in audit visit is the portable Power Quality Analyzers (PQA for measuring single to three-phase lines with a high degree of precision and accuracy. It is utilized for monitoring and recording power supply anomalies. For most survey applications, changing currents makes it mandatory for data to be compiled over a period of time with enormous amount of electricity data. Hence, this paper proposed a Business Intelligence approach that can facilitate the auditor to quickly analyze the PQA data. There are five Key Performance Indicators (KPI to be displayed for analyze in form of dashboard. The method that uses to construct the dashboard is classification and association rules with the help of orange dataminer tools. Classification method is utilized to display the data distributions by frequency on a bar chart. Once we got the frequent sets, they allow us to extract association rules among the item sets, where we make some statement about how likely are two sets of items to co-occur or to conditionally occur. The result of this paper is a dashboard of five scorecards, namely unbalanced voltage, unbalanced currents, voltage harmonic, currents harmonic, and power factor. 

  2. Immunofluorescence in cytogenetic analysis: method and applications

    Directory of Open Access Journals (Sweden)

    Jeppesen Peter


    Full Text Available Control of the genetic information encoded by DNA in mammalian chromosomes is mediated by proteins, some of which are only transiently attached, although others are intrinsically associated with nucleic acid in the complex mixture known as chromatin. Chromatin-associated proteins range from the ubiquitous and abundant histones down to the most specific and rare of transcription factors. Although many chromatin proteins are probably excluded from highly condensed mitotic chromosomes, a number are retained throughout the cell cycle and can be detected on chromosomes in metaphase spreads. Comparing the distribution of a chromosomal protein with known cytogenetic markers on metaphase chromosomes can provide an important and potentially highly informative first source of data on the function of the protein under consideration. The aim of the present study is to summarize some of the principles involved in obtaining suitable chromosome preparations for subsequent immunolocalization of protein antigens. Some applications of the method will be included to illustrate how this approach has increased our understanding of chromosome structure and genetic regulation.

  3. Eye movement analysis for activity recognition using electrooculography. (United States)

    Bulling, Andreas; Ward, Jamie A; Gellersen, Hans; Tröster, Gerhard


    In this work, we investigate eye movement analysis as a new sensing modality for activity recognition. Eye movement data were recorded using an electrooculography (EOG) system. We first describe and evaluate algorithms for detecting three eye movement characteristics from EOG signals-saccades, fixations, and blinks-and propose a method for assessing repetitive patterns of eye movements. We then devise 90 different features based on these characteristics and select a subset of them using minimum redundancy maximum relevance (mRMR) feature selection. We validate the method using an eight participant study in an office environment using an example set of five activity classes: copying a text, reading a printed paper, taking handwritten notes, watching a video, and browsing the Web. We also include periods with no specific activity (the NULL class). Using a support vector machine (SVM) classifier and person-independent (leave-one-person-out) training, we obtain an average precision of 76.1 percent and recall of 70.5 percent over all classes and participants. The work demonstrates the promise of eye-based activity recognition (EAR) and opens up discussion on the wider applicability of EAR to other activities that are difficult, or even impossible, to detect using common sensing modalities.

  4. Neutron activation analysis of some building materials (United States)

    Salagean, M. N.; Pantelica, A. I.; Georgescu, I. I.; Muntean, M. I.


    Concentrations of As, Au, Ba, Br, Ca, Ce, Co, Cr, Cs, Eu, Fe, Hf, K, La, Lu, Mo, Na, Nd, Rb, Sb, Sc, Sr, Ta, Tb, Th, U. Yb, W and Zn in seven Romanian building materials were determined by the Instrumental Neutron Activation Analysis (INAA) method using the VVR-S Reactor of NIPNE- Bucharest. Raw matarials used in cement obtaining ≈ 75% of limestone and ≈ 25% of clay, cement samples from three different factories, furnace slag, phosphogypsum, and a type of brick have been analyzed. The brick was compacted from furnace slay, fly coal ash, phosphogypsum, lime and cement. The U, Th and K concentrations determined in the brick are in agreement with the natural radioactivity measurements of226Ra,232Th and40K. These specific activities were found about twice and 1.5 higher than the accepted levels in the case of226Ra and232Th, as well as40K, respectively. By consequence, the investigated brick is considered a radioactive waste. The rather high content of Co, Cr, K, Th, and Zh in the brick is especially due to the slag and fly ash, the main componets. The presence of U, Th and K in slag is mainly correlated with the limestone and dolomite as fluxes in matallurgy.

  5. Application of neutron activation analysis for the determination of essential elements in egg samples; Aplicacao da analise por ativacao com neutrons para a determinacao de elementos essenciais em amostras de ovos

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Bruna G.; Maihara, Vera A.; Avegliano, Roseane P., E-mail:, E-mail:, E-mail: [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)


    The eggs are among the twenty foods consumed by the population of the five major regions of Brazil. Among the types of eggs, there are differences in nutritional value, which can vary according to the food of the bird. This study evaluating the elements Cl, K, Mg, Mn and Na considered essential micronutrients in food, because they are fundamental in several metabolic processes necessary for the maintenance and training of the human body. We analyzed three types of eggs: egg whites, of the quail, and the colonial in cooked and raw form, using the Instrumental Neutron Activation Analysis method (INAA). The egg samples were lyophilized and pulverized before analysis. To validate the methodology, reference materials NIST RM 8415 Whole Egg Powder and NIST SRM 1567 Wheat Flour were analyzed. The samples, reference materials and standards of the elements were irradiated for 20 seconds under a thermal neutron flux of 6,6x10{sup 12} cm -2 s -1 in the nuclear research reactor IEA-R1 of IPEN-CNEN / SP. The results were consistent with the values of the Brazilian Table of Food Composition (TACO)

  6. 2nd International Workshop on Isogeometric Analysis and Applications

    CERN Document Server

    Simeon, Bernd


    Isogeometric Analysis is a groundbreaking computational approach that promises the possibility of integrating the finite element  method into conventional spline-based CAD design tools. It thus bridges the gap between numerical analysis and geometry, and moreover it allows to tackle new cutting edge applications at the frontiers of research in science and engineering. This proceedings volume contains a selection of outstanding research papers presented at the second International Workshop on Isogeometric Analysis and Applications, held at Annweiler, Germany, in April 2014.

  7. Single cell analysis contemporary research and clinical applications

    CERN Document Server

    Cossarizza, Andrea


    This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.

  8. Advances in real and complex analysis with applications

    CERN Document Server

    Cho, Yeol; Agarwal, Praveen; Area, Iván


    This book discusses a variety of topics in mathematics and engineering as well as their applications, clearly explaining the mathematical concepts in the simplest possible way and illustrating them with a number of solved examples. The topics include real and complex analysis, special functions and analytic number theory, q-series, Ramanujan’s mathematics, fractional calculus, Clifford and harmonic analysis, graph theory, complex analysis, complex dynamical systems, complex function spaces and operator theory, geometric analysis of complex manifolds, geometric function theory, Riemannian surfaces, Teichmüller spaces and Kleinian groups, engineering applications of complex analytic methods, nonlinear analysis, inequality theory, potential theory, partial differential equations, numerical analysis , fixed-point theory, variational inequality, equilibrium problems, optimization problems, stability of functional equations, and mathematical physics.  It includes papers presented at the 24th International Confe...

  9. Applications of electronic noses in meat analysis

    Directory of Open Access Journals (Sweden)



    Full Text Available Abstract Electronic noses are devices able to characterize and differentiate the aroma profiles of various food, especially meat and meat products. During recent years e-noses have been widely used in food analysis and proved to provide a fast, simple, non-expensive and non-destructive method of food assessment and quality control. The aim of this study is to summarize the most important features of this analytic tool and to present basic fields and typical areas of e-nose use as well as most commonly used sensor types and patterns for e-nose design. Prospects for the future development of this technique are presented. Methods and research results presented in this manuscript may be a guideline for practical e-nose use.

  10. Chemical activation using an open-end coaxial applicator. (United States)

    Longo, Iginio; Ricci, Andrea Simone


    This article gives an overview of a novel, experimentally simple and versatile method of activation of chemical processes with microwaves without resorting to an oven. It is based on the use of a microwave antenna, namely an open-end coaxial dipole applicator immersed in an ordinary reaction vessel. Accounts of the apparatus at 2450 MHz and of the procedures adopted in reactions of organic synthesis, extraction of essential oils from plants and photo catalytic mineralization of liquid pollutants are given, discussing the necessary safety measures. The method is of practical interest for scientific and industrial applications. Thus this article is meant for a broad audience of scientists, engineers and technicians interested in new technologies for chemistry.

  11. Orthodontic Force Application in Correlation with Salivary Lactate Dehydrogenase Activity

    Directory of Open Access Journals (Sweden)

    Erik Husin


    Full Text Available Orthodontic tooth movement generate mechanical forces to periodontal ligament and alveolar bone. The forces correlate with initial responses of periodontal tissues and involving many metabolic changes. One of the metabolic changes detected in saliva is lactate dehydrogenase (LDH activity. Objectives: To evaluate the correlation between orthodontic interrupted force application, lactate dehydrogenase activity and the distance of tooth movement. Methods: upper premolar, pre-retraction of upper canine and 1, 7, 14, 21 and 28 days post-retraction of upper canine with 100g interrupted orthodontic force. Results: duration of force (F=11.926 p 14 and 28 days post-retraction of canine. The region of retraction correlated with the distance of tooth movement (F=7.377 p=0.007. The duration of force correlated with the distance of tooth movement (F=66.554 p=0.000. retraction of canine. Conclusion: This study concluded that orthodontic interrupted force application on canine could increase the distance of tooth movement and LDH activity in saliva.

  12. Strategic marketing applications of conjoint analysis: an HMO perspective. (United States)

    Rosko, M D; DeVita, M; McKenna, W F; Walker, L R


    The purpose of this article is to demonstrate how data from a conjoint analysis study can be used to help determine the most appropriate marketing mix for an operational HMO which is entering a new market--the geriatric population. Included are two features which are absent in previous articles on health care applications of conjoint analysis: external validation of results, and a demonstration of how conjoint analysis can be used to simulate market responses to changes in the provider's marketing mix.

  13. [Effects of different fertilizer application on soil active organic carbon]. (United States)

    Zhang, Rui; Zhang, Gui-Long; Ji, Yan-Yan; Li, Gang; Chang, Hong; Yang, Dian-Lin


    The variation characteristics of the content and components of soil active organic carbon under different fertilizer application were investigated in samples of calcareous fluvo-aquic soil from a field experiment growing winter wheat and summer maize in rotation in the North China Plain. The results showed that RF (recommended fertilization), CF (conventional fertilization) and NPK (mineral fertilizer alone) significantly increased the content of soil dissolved organic carbon and easily oxidized organic carbon by 24.92-38.63 mg x kg(-1) and 0.94-0.58 mg x kg(-1) respectively compared to CK (unfertilized control). The soil dissolved organic carbon content under OM (organic manure) increased greater than those under NPK and single fertilization, soil easily oxidized organic carbon content under OM and NPK increased greater than that under single chemical fertilization. OM and NPK showed no significant role in promoting the soil microbial biomass carbon, but combined application of OM and NPK significantly increased the soil microbial biomass carbon content by 36.06% and 20.69%, respectively. Soil easily oxidized organic carbon, dissolved organic carbon and microbial biomass carbon accounted for 8.41% - 14.83%, 0.47% - 0.70% and 0.89% - 1.20% of the total organic carbon (TOC), respectively. According to the results, the fertilizer application significantly increased the proportion of soil dissolved organic carbon and easily oxidized organic carbon, but there was no significant difference in the increasing extent of dissolved organic carbon. The RF and CF increased the proportion of soil easily oxidized organic carbon greater than OM or NPK, and significantly increased the proportion of microbial biomass carbon. OM or RF had no significant effect on the proportion of microbial biomass carbon. Therefore, in the field experiment, appropriate application of organic manure and chemical fertilizers played an important role for the increase of soil active organic carbon

  14. Operating cost analysis of anaesthesia: Activity based costing (ABC analysis

    Directory of Open Access Journals (Sweden)

    Majstorović Branislava M.


    Full Text Available Introduction. Cost of anaesthesiology represent defined measures to determine a precise profile of expenditure estimation of surgical treatment, which is important regarding planning of healthcare activities, prices and budget. Objective. In order to determine the actual value of anaestesiological services, we started with the analysis of activity based costing (ABC analysis. Methods. Retrospectively, in 2005 and 2006, we estimated the direct costs of anestesiological services (salaries, drugs, supplying materials and other: analyses and equipment. of the Institute of Anaesthesia and Resuscitation of the Clinical Centre of Serbia. The group included all anesthetized patients of both sexes and all ages. We compared direct costs with direct expenditure, “each cost object (service or unit” of the Republican Health-care Insurance. The Summary data of the Departments of Anaesthesia documented in the database of the Clinical Centre of Serbia. Numerical data were utilized and the numerical data were estimated and analyzed by computer programs Microsoft Office Excel 2003 and SPSS for Windows. We compared using the linear model of direct costs and unit costs of anaesthesiological services from the Costs List of the Republican Health-care Insurance. Results. Direct costs showed 40% of costs were spent on salaries, (32% on drugs and supplies, and 28% on other costs, such as analyses and equipment. The correlation of the direct costs of anaestesiological services showed a linear correlation with the unit costs of the Republican Healthcare Insurance. Conclusion. During surgery, costs of anaesthesia would increase by 10% the surgical treatment cost of patients. Regarding the actual costs of drugs and supplies, we do not see any possibility of costs reduction. Fixed elements of direct costs provide the possibility of rationalization of resources in anaesthesia.

  15. [Operating cost analysis of anaesthesia: activity based costing (ABC analysis)]. (United States)

    Majstorović, Branislava M; Kastratović, Dragana A; Vučović, Dragan S; Milaković, Branko D; Miličić, Biljana R


    Cost of anaesthesiology represent defined measures to determine a precise profile of expenditure estimation of surgical treatment, which is important regarding planning of healthcare activities, prices and budget. In order to determine the actual value of anaestesiological services, we started with the analysis of activity based costing (ABC) analysis. Retrospectively, in 2005 and 2006, we estimated the direct costs of anestesiological services (salaries, drugs, supplying materials and other: analyses and equipment.) of the Institute of Anaesthesia and Resuscitation of the Clinical Centre of Serbia. The group included all anesthetized patients of both sexes and all ages. We compared direct costs with direct expenditure, "each cost object (service or unit)" of the Republican Healthcare Insurance. The Summary data of the Departments of Anaesthesia documented in the database of the Clinical Centre of Serbia. Numerical data were utilized and the numerical data were estimated and analyzed by computer programs Microsoft Office Excel 2003 and SPSS for Windows. We compared using the linear model of direct costs and unit costs of anaesthesiological services from the Costs List of the Republican Healthcare Insurance. Direct costs showed 40% of costs were spent on salaries, (32% on drugs and supplies, and 28% on other costs, such as analyses and equipment. The correlation of the direct costs of anaestesiological services showed a linear correlation with the unit costs of the Republican Healthcare Insurance. During surgery, costs of anaesthesia would increase by 10% the surgical treatment cost of patients. Regarding the actual costs of drugs and supplies, we do not see any possibility of costs reduction. Fixed elements of direct costs provide the possibility of rationalization of resources in anaesthesia.

  16. and application to autopilot performance analysis

    Directory of Open Access Journals (Sweden)

    Daniel E. Davison


    Full Text Available This paper deals with the notion of disturbance model uncertainty. The disturbance is modeled as the output of a first-order filter which is driven by white noise and whose bandwidth and gain are uncertain. An analytical expression for the steady-state output variance as a function of the uncertain bandwidth and gain is derived, and several properties of this variance function are analyzed. Two notions, those of disturbance bandwidth margin and disturbance gain margin are also introduced. These tools are then applied to the analysis of a simple altitude-hold autopilot system in the presence of turbulence where the turbulence scale is treated as an uncertain parameter. It is shown that the autopilot, which is satisfactory for nominal turbulence scale, may be inadequate when the uncertainty is taken into account. Moreover, it is proven that, in order to obtain a design that provides robust performance in the face of turbulence scale uncertainty, it is necessary to substantially increase the controller bandwidth, even if one is willing to sacrifice the autopilot's holding ability and stability robustness.

  17. Structural Investigation of Alkali Activated Clay Minerals for Application in Water Treatment Systems (United States)

    Bumanis, G.; Bajare, D.; Dembovska, L.


    Alkali activation technology can be applied for a wide range of alumo-silicates to produce innovative materials with various areas of application. Most researches focuse on the application of alumo-silicate materials in building industry as cement binder replacement to produce mortar and concrete [1]. However, alkali activation technology offers high potential also in biotechnologies [2]. In the processes where certain pH level, especially alkaline environment, must be ensured, alkali activated materials can be applied. One of such fields is water treatment systems where high level pH (up to pH 10.5) ensures efficient removal of water pollutants such as manganese [3]. Previous investigations had shown that alkali activation technology can be applied to calcined clay powder and aluminium scrap recycling waste as a foam forming agent to create porous alkali activated materials. This investigation focuses on the structural investigation of calcined kaolin and illite clay alkali activation processes. Chemical and mineralogical composition of both clays were determined and structural investigation of alkali activated materials was made by using XRD, DTA, FTIR analysis; the microstructure of hardened specimens was observed by SEM. Physical properties of the obtained material were determined. Investigation indicates the essential role of chemical composition of the clay used in the alkali activation process, and potential use of the obtained material in water treatment systems.

  18. Provenience studies using neutron activation analysis: the role of standardization

    Energy Technology Data Exchange (ETDEWEB)

    Harbottle, G


    This paper covers the historical background of chemical analysis of archaeological artifacts which dates back to 1790 to the first application of neutron activation analysis to archaeological ceramics and goes on to elaborate on the present day status of neutron activation analysis in provenience studies, and the role of standardization. In principle, the concentrations of elements in a neutron-activated specimen can be calculated from an exact knowledge of neutron flux, its intensity, duration and spectral (energy) distribution, plus an exact gamma ray count calibrated for efficiency, corrected for branching rates, etc. However, in practice it is far easier to compare one's unknown to a standard of known or assumed composition. The practice has been for different laboratories to use different standards. With analyses being run in the thousands throughout the world, a great benefit would be derived if analyses could be exchanged among all users and/or generators of data. The emphasis of this paper is on interlaboratory comparability of ceramic data; how far are we from it, what has been proposed in the past to achieve this goal, and what is being proposed. All of this may be summarized under the general heading of Analytical Quality Control - i.e., how to achieve precise and accurate analysis. The author proposes that anyone wishing to analyze archaeological ceramics should simply use his own standard, but attempt to calibrate that standard as nearly as possible to absolute (i.e., accurate) concentration values. The relationship of Analytical Quality Control to provenience location is also examined.

  19. Activity modelling for assessing the usability of telematics applications in healthcare. (United States)

    Beuscart-Zéphir, M C; Sockeel, P; Bossard, B; Beuscart, R


    With the development of Telematics Applications in Healthcare, it becomes obvious that the success of these services is tightly linked with their usability and their acceptance by users. That is why Users Requirements Analysis appears as an essential step before implementation of new computer services. In many cases, particularly when doctors are directly involved in the management of information, there is a strong interaction between their usual activity and the new tasks implied by the computer. In those cases, Activity Modelling can be useful to describe the way people are working, the motivations that underlie this activity, the place of information management in this activity. Moreover, these models can help to forecast possible difficulties or reasons for failure of the data management when computerised. Obviously, these models are highly depending on the healthcare organisation but some basic lines can be transferable. In this paper we illustrate the Activity Modelling Methodology by examples from Telematics exchanges between GPs and Hospitals.

  20. Activity-Based Costing Application in an Urban Mass Transport Company

    Directory of Open Access Journals (Sweden)

    Popesko Boris


    Full Text Available The purpose of this paper is to provide a basic overview of the application of Activity-Based Costing in an urban mass transport company which operates land public transport via buses and trolleys within the city. The case study was conducted using the Activity-Based Methodology in order to calculate the true cost of individual operations and to measure the profitability of particular transport lines. The case study analysis showed the possible effects of the application of the Activity-Based Costing for an urban mass transport company as well as the limitations of using the ABC methodology in the service industry. With regards to the application of the ABC methodology, the primary limitation of the accuracy of the conclusions is the quality of the non-financial information which had to be gathered throughout the implementation process. A basic limitation of the accurate data acquisition is the nature of the fare system of the transport company which does not allow the identification of the route that is taken by an individual passenger. The study illustrates the technique of ABC in urban mass transport and provides a real company example of information outputs of the ABC system. The users indicated that, the ABC model is very useful for profitability reporting and profit management. Also, the paper shows specific application of the Activity-Based Methodology in conditions of urban mass transport companies with regional specifics.

  1. Camera systems in human motion analysis for biomedical applications (United States)

    Chin, Lim Chee; Basah, Shafriza Nisha; Yaacob, Sazali; Juan, Yeap Ewe; Kadir, Aida Khairunnisaa Ab.


    Human Motion Analysis (HMA) system has been one of the major interests among researchers in the field of computer vision, artificial intelligence and biomedical engineering and sciences. This is due to its wide and promising biomedical applications, namely, bio-instrumentation for human computer interfacing and surveillance system for monitoring human behaviour as well as analysis of biomedical signal and image processing for diagnosis and rehabilitation applications. This paper provides an extensive review of the camera system of HMA, its taxonomy, including camera types, camera calibration and camera configuration. The review focused on evaluating the camera system consideration of the HMA system specifically for biomedical applications. This review is important as it provides guidelines and recommendation for researchers and practitioners in selecting a camera system of the HMA system for biomedical applications.

  2. Direct analysis of prostaglandin-E2 and -D2 produced in an inflammatory cell reaction and its application for activity screening and potency evaluation using turbulent flow chromatography liquid chromatography-high resolution mass spectrometry. (United States)

    Shin, Jeong-Sook; Peng, Lei; Kang, Kyungsu; Choi, Yongsoo


    Direct analysis of prostaglandin-E2 (PGE2) and -D2 (PGD2) produced from a RAW264.7 cell-based reaction was performed by liquid chromatography high-resolution mass spectrometry (LC-HRMS), which was online coupled with turbulent flow chromatography (TFC). The capability of this method to accurately measure PG levels in cell reaction medium containing cytokines or proteins as a reaction byproduct was cross-validated by two conventional methods. Two methods, including an LC-HRMS method after liquid-liquid extraction (LLE) of the sample and a commercial PGE2 enzyme-linked immunosorbent assay (ELISA), showed PGE2 and/or PGD2 levels almost similar to those obtained by TFC LC-HRMS over the reaction time after LPS stimulation. After the cross-validation, significant analytical throughputs, allowing simultaneous screening and potency evaluation of 80 natural products including 60 phytochemicals and 20 natural product extracts for the inhibition of the PGD2 produced in the cell-based inflammatory reaction, were achieved using the TFC LC-HRMS method developed. Among the 60 phytochemicals screened, licochalcone A and formononetin inhibited PGD2 production the most with IC50 values of 126 and 151nM, respectively. For a reference activity, indomethacin and diclofenac were used, measuring IC50 values of 0.64 and 0.21nM, respectively. This method also found a butanol extract of Akebia quinata Decne (AQ) stem as a promising natural product for PGD2 inhibition. Direct and accurate analysis of PGs in the inflammatory cell reaction using the TFC LC-HRMS method developed enables the high-throughput screening and potency evaluation of as many as 320 samples in less than 48h without changing a TFC column. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Quaternion Singular Spectrum Analysis of Electroencephalogram With Application in Sleep Analysis. (United States)

    Enshaeifar, Shirin; Kouchaki, Samaneh; Took, Clive Cheong; Sanei, Saeid


    A novel quaternion-valued singular spectrum analysis (SSA) is introduced for multichannel analysis of electroencephalogram (EEG). The analysis of EEG typically requires the decomposition of data channels into meaningful components despite the notoriously noisy nature of EEG--which is the aim of SSA. However, the singular value decomposition involved in SSA implies the strict orthogonality of the decomposed components, which may not reflect accurately the sources which exhibit similar neural activities. To allow for the modelling of such co-channel coupling, the quaternion domain is considered for the first time to formulate the SSA using the augmented statistics. As an application, we demonstrate how the augmented quaternion-valued SSA (AQSSA) can be used to extract the sources, even at a signal-to-noise ratio as low as -10 dB. To illustrate the usefulness of our quaternion-valued SSA in a rehabilitation setting, we employ the proposed SSA for sleep analysis to extract statistical descriptors for five-stage classification (Awake, N1, N2, N3 and REM). The level of agreement using these descriptors was 74% as quantified by the Cohen's kappa.

  4. Finite element analysis theory and application with ANSYS

    CERN Document Server

    Moaveni, Saeed


    For courses in Finite Element Analysis, offered in departments of Mechanical or Civil and Environmental Engineering. While many good textbooks cover the theory of finite element modeling, Finite Element Analysis: Theory and Application with ANSYS is the only text available that incorporates ANSYS as an integral part of its content. Moaveni presents the theory of finite element analysis, explores its application as a design/modeling tool, and explains in detail how to use ANSYS intelligently and effectively. Teaching and Learning Experience This program will provide a better teaching and learning experience-for you and your students. It will help: *Present the Theory of Finite Element Analysis: The presentation of theoretical aspects of finite element analysis is carefully designed not to overwhelm students. *Explain How to Use ANSYS Effectively: ANSYS is incorporated as an integral part of the content throughout the book. *Explore How to Use FEA as a Design/Modeling Tool: Open-ended design problems help stude...

  5. Using Transcription and Replay in Analysis of Collaborative Applications (United States)


    of Action, Brandeis University. Alterman, R., S. Landsman, et al. (1998). Groupware for Planning, Computer Science Department, Brandeis University... Groupware Applications: Building Groupware On THYME, Brandeis University. Landsman, S., R. Alterman, et al. (2001). VesselWorld and ADAPTIVE, Dept of...reserved.Approved for Public Release ■Allows ethnographic analysis of groupware application use – Online behavior can be captured and recreated exactly

  6. Chaos in electric drive systems analysis control and application

    CERN Document Server

    Chau, K T


    In Chaos in Electric Drive Systems: Analysis, Control and Application authors Chau and Wang systematically introduce an emerging technology of electrical engineering that bridges abstract chaos theory and practical electric drives. The authors consolidate all important information in this interdisciplinary technology, including the fundamental concepts, mathematical modeling, theoretical analysis, computer simulation, and hardware implementation. The book provides comprehensive coverage of chaos in electric drive systems with three main parts: analysis, control and application. Corresponding drive systems range from the simplest to the latest types: DC, induction, synchronous reluctance, switched reluctance, and permanent magnet brushless drives.The first book to comprehensively treat chaos in electric drive systemsReviews chaos in various electrical engineering technologies and drive systemsPresents innovative approaches to stabilize and stimulate chaos in typical drivesDiscusses practical application of cha...

  7. Electrochemically Active Biofilms Assisted Nanomaterial Synthesis for Environmental Applications

    KAUST Repository

    Ahmed, Elaf


    Nanomaterials have a great potential for environmental applications due to their high surface areas and high reactivity. This dissertation investigated the use of electrochemically active biofilms (EABs) as a synthesis approach for the fabrication and environmental applications of different nanomaterials. Bacteria in EABs generate electrons upon consuming electron donor and have the ability to transport these electrons to solid or insoluble substrates through extracellular electron transport (EET) mechanism. The extracellularly transported electrons, once utilized, can lead to nanoparticle synthesis. In this dissertation, noble metal (i.e., Au, Pd, and Pt) ultra-small nanoparticles (USNPs) were first synthesized with the assistance by the EABs. The assynthesized USNPs had a size range between 2 and 7 nm and exhibited excellent catalytic performance in dye decomposition. Also in this research, a two-dimensional (2D) cobalt nanosheet was successfully synthesized in the presence of EABs. A simple biogenic route led to the transformation of cobalt acetate to produce a green, toxic free homogeneous 2D cobalt nanosheet structure. Further, TiO2 nanotubes were successfully combined with the noble metal USNPs to enhance their photocatalytic activity. In this work, for the first time, the noble metal USNPs were directly reduced and decorated on the internal surfaces of the TiO2 nanotubes structure assisted by the EABs. The USNPs modified TiO2 nanotubes generated significantly improved photoelectrocatatlyic performances. This dissertation shines lights on the use of EABs in ultra-small nanoparticle synthesis.

  8. Effect of gypsum application on enzymatic browning activity in lettuce. (United States)

    Chutichudet, Prasit; Chutichudet, B; Kaewsit, S


    A comprehensive study to evaluate calcium, in terms of gypsum (CaSO4.2H2O) by soil dressing application, on enzymatic browning activity of Polyphenol oxidase (PPO) and internal qualities was tested on lettuce var. Grand Rapids under field conditions. A factorial in completely randomized design was arranged with four replications. The results showed that plants-treated with 50 mg kg(-1) gypsum applied at 40 DAP had the maximal fresh weight of 25.83 g plant(-1). The internal qualities of the lettuce at harvest showed that plants treated with 50 mg kg(-1) gypsum had the maximal chlorophyll content (26.80 mg m(-2)), while all gypsum concentrations applied in this study, had less content of ascorbic acid than the control plants. Plants-treated with 100 mg kg(-1) gypsum affected to the lowest level of PPO activity at week 3 after transplanting. Furthermore, gypsum application had no effect to biomass, leaf colour, the contents of phenolic and quinone in lettuce at harvesting stage.

  9. Electrocatalytic activity of ordered intermetallic phases for fuel cell applications. (United States)

    Casado-Rivera, Emerilis; Volpe, David J; Alden, Laif; Lind, Cora; Downie, Craig; Vázquez-Alvarez, Terannie; Angelo, Antonio C D; DiSalvo, Francis J; Abruña, Héctor D


    The electrocatalytic activities of a wide range of ordered intermetallic phases toward a variety of potential fuels have been studied, and results have been compared to those of a pure polycrystalline platinum (Pt(pc)) electrode. A significant number of the ordered intermetallic phases exhibited enhanced electrocatalytic activity when compared to that of Pt, in terms of both oxidation onset potential and current density. The PtBi, PtIn, and PtPb ordered intermetallic phases appeared to be the most promising electrocatalysts tested thus far for fuel cell applications. PtPb, in particular, showed an onset potential that was 100 mV less positive and a peak current density approximately 40 times higher than those observed for Pt in the case of methanol oxidation. The ability to control the geometric and electronic structures of the electrocatalytic material by using ordered intermetallic phases has been shown to be a promising direction of inquiry in the search for superior electrocatalysts for fuel cell applications.

  10. Neutron activation analysis application for determining iron concentration in forage grasses used in intensive cattle production system; Aplicacao da analise por ativacao com neutrons para determinacao de ferro em forrageiras usadas no sistema intensivo de producao de bovinos de leite

    Energy Technology Data Exchange (ETDEWEB)

    Armelin, Maria Jose A. [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil); Primavesi, Odo [Empresa Brasileira de Pesquisa Agropecuaria, Sao Carlos, SP (Brazil). Centro de Pesquisa de Pecuaria do Sudeste


    Iron is an essential element to the life. It is an important hemoglobin component and it is involved in the transport of oxygen to cells. A deficiency of iron results in an unsuitable synthesis of hemoglobin and a delay in the growth. Iron contents above the tolerable level in animal feed can cause serious damages to the health and the death in extreme cases. The forages are the main source of feed to cattle in grazing. It is known from the literature, that the growth and the nutritious value of the forage are influenced by specie and physiologic age of the plant, soil fertility and environmental conditions. Therefore, an agronomical evaluations of the forages are necessary before to introduce in an intensive cattle production systems to program adequate grazing management. Neutron activation analysis was applied to evaluate the Fe concentration in the main tropical forage grasses used in intensive dairy cattle production systems in Sao Carlos, SP, Brazil. Iron concentrations were smaller in the rain season than in the dry one. Comparison of results obtained in the analyses of forages with daily requirements of iron in dry matter, showed that the Fe concentration in forages was adequate. (author)

  11. The application of FRET biosensors to visualize Src activation (United States)

    Wang, Yingxiao; Lu, Shaoying


    Src kinase, the first tyrosine kinase discovered, has been shown to play critical roles in a variety of cellular processes, including cell motility/migration, mechanotranduction, and cancer development. Based on fluorescent resonance energy transfer (FRET), we have developed and characterized a genetically encoded single-molecule Src biosensor, which enables the imaging and quantification of temporal-spatial activation of Src in live cells. In this paper, we summarize the application of this biosensor to study a variety of cellular functions. First, we introduced a local mechanical stimulation by applying laser-tweezer-induced traction on fibronectin-coated beads adhered to the cells. Using a membrane-anchored Src biosensor, we observed a wave propagation of Src activation in a direction opposite to the applied force. This Src reporter was also applied to visualize the interplays between cell-cell and cell-ECM adhesions. The results indicate that integrin-ligation can induce Src activation around cell-cell junctions and cause the disruption of adherens junctions. Lastly, the flow-induced dynamic Src activation at subcellular levels was visualized by the FRET biosensor simultaneously with actin-fused mCherry, a red fluorescence protein. Our results indicate that shear stress induced a moderate up-regulation of Src activation in the whole cell, but a significant translocation of active Src from perinuclear regions toward cell periphery. In summary, our novel Src biosensor has made it possible to monitor key signaling transduction cascades involving Src in live cells with temporal-spatial characterization in mechanobiology.

  12. Urban transportation energy conservation: case city applications of analysis methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Atherton, T.J.; Suhrbier, J.H.


    This report demonstrates the application of a set of disaggregate travel demand methodologies to the analysis of potential energy conservation strategies in three urban areas: Denver, Colorado; Fort Worth, Texas; and San Francisco, California. The methodologies are sketch planning in nature and include the forecasting of changes in automobile ownership; work trip model shares by drive alone, shared ride, and transit; non-work trip frequency, destination, and mode choice; fuel consumption and vehicle emissions. Using concepts of market segmentation and random sample household aggregation, both computer system and manual worksheet versions of the basic approach are applied. Policies analyzed include those related as employer based ride sharing, parking management, transit, pricing, and traffic operations. Considerable variations in the potential effectiveness was found, among the three urban areas, depending in large part on the availability of alternative travel modes such as transit. Descriptions are provided of the individual policy analyses performed, the methods by which example policies were analyzed, the necessary data preparation activities, and the procedures used to adapt the set of travel demand models to the unique conditions of each of the three metropolitan areas.

  13. On the Deployment of Dynamic Taint Analysis for Application Communities (United States)

    Kim, Hyung Chan; Keromytis, Angelos

    Although software-attack detection via dynamic taint analysis (DTA) supports high coverage of program execution, it prohibitively degrades the performance of the monitored program. This letter explores the possibility of collaborative dynamic taint analysis among members of an application community (AC): instead of full monitoring for every request at every instance of the AC, each member uses DTA for some fraction of the incoming requests, thereby loosening the burden of heavyweight monitoring. Our experimental results using a test AC based on the Apache web server show that speedy detection of worm outbreaks is feasible with application communities of medium size (i.e., 250-500).

  14. Spectral theory and nonlinear analysis with applications to spatial ecology

    CERN Document Server

    Cano-Casanova, S; Mora-Corral , C


    This volume details some of the latest advances in spectral theory and nonlinear analysis through various cutting-edge theories on algebraic multiplicities, global bifurcation theory, non-linear Schrödinger equations, non-linear boundary value problems, large solutions, metasolutions, dynamical systems, and applications to spatial ecology. The main scope of the book is bringing together a series of topics that have evolved separately during the last decades around the common denominator of spectral theory and nonlinear analysis - from the most abstract developments up to the most concrete applications to population dynamics and socio-biology - in an effort to fill the existing gaps between these fields.

  15. 78 FR 4155 - Agency Information Collection Activities: Application for Foreign Trade Zone and/or Status... (United States)


    ... Foreign Trade Zone and/or Status Designation, and Application for Foreign Trade Zone Activity Permit... Application for Foreign Trade Zone Admission and/or Status Designation, and Application for Foreign Trade Zone... Foreign Trade Zone Admission and/or Status Designation, and Application for Foreign Trade Zone Activity...

  16. Advanced symbolic analysis for VLSI systems methods and applications

    CERN Document Server

    Shi, Guoyong; Tlelo Cuautle, Esteban


    This book provides comprehensive coverage of the recent advances in symbolic analysis techniques for design automation of nanometer VLSI systems. The presentation is organized in parts of fundamentals, basic implementation methods and applications for VLSI design. Topics emphasized include  statistical timing and crosstalk analysis, statistical and parallel analysis, performance bound analysis and behavioral modeling for analog integrated circuits . Among the recent advances, the Binary Decision Diagram (BDD) based approaches are studied in depth. The BDD-based hierarchical symbolic analysis approaches, have essentially broken the analog circuit size barrier. In particular, this book   • Provides an overview of classical symbolic analysis methods and a comprehensive presentation on the modern  BDD-based symbolic analysis techniques; • Describes detailed implementation strategies for BDD-based algorithms, including the principles of zero-suppression, variable ordering and canonical reduction; • Int...


    Directory of Open Access Journals (Sweden)



    Full Text Available Surface electromyography (SEMG is a technique for detecting and recording the electrical activity of the muscles using surface electrodes. The EMG signal is used in biomechanics mainly as an indicator of the initiation of muscle activation, as an indicator of the force produced by a contracting muscle, and as an index ofthe fatigue occurring within a muscle. EMG, used as a method of investigation, can tell us if the muscle is active or not, if the muscle is more or less active, when it is on or off, how much active is it, and finally, if it fatigues.The purpose of this article is to discuss some specific EMG signal analysis aspects with emphasis on comparison type analysis and frequency fatigue analysis.

  18. [Application of chemometrics in composition-activity relationship research of traditional Chinese medicine]. (United States)

    Han, Sheng-Nan


    Chemometrics is a new branch of chemistry which is widely applied to various fields of analytical chemistry. Chemometrics can use theories and methods of mathematics, statistics, computer science and other related disciplines to optimize the chemical measurement process and maximize access to acquire chemical information and other information on material systems by analyzing chemical measurement data. In recent years, traditional Chinese medicine has attracted widespread attention. In the research of traditional Chinese medicine, it has been a key problem that how to interpret the relationship between various chemical components and its efficacy, which seriously restricts the modernization of Chinese medicine. As chemometrics brings the multivariate analysis methods into the chemical research, it has been applied as an effective research tool in the composition-activity relationship research of Chinese medicine. This article reviews the applications of chemometrics methods in the composition-activity relationship research in recent years. The applications of multivariate statistical analysis methods (such as regression analysis, correlation analysis, principal component analysis, etc. ) and artificial neural network (such as back propagation artificial neural network, radical basis function neural network, support vector machine, etc. ) are summarized, including the brief fundamental principles, the research contents and the advantages and disadvantages. Finally, the existing main problems and prospects of its future researches are proposed.

  19. Chemical composition, antimicrobial activity, proximate analysis and ...

    African Journals Online (AJOL)

    The extract showed significant antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus kristinae, Streptococcus faecalis, Shigella flexneri, Klebsiella pneumonia, Serratia marcescens and antifungal activity against Aspergillus flavus, Aspergillus niger and Penicillium notatum.

  20. Functionalized Activated Carbon Derived from Biomass for Photocatalysis Applications Perspective

    Directory of Open Access Journals (Sweden)

    Samira Bagheri


    Full Text Available This review highlighted the developments of safe, effective, economic, and environmental friendly catalytic technologies to transform lignocellulosic biomass into the activated carbon (AC. In the photocatalysis applications, this AC can further be used as a support material. The limits of AC productions raised by energy assumption and product selectivity have been uplifted to develop sustainable carbon of the synthesis process, where catalytic conversion is accounted. The catalytic treatment corresponding to mild condition provided a bulk, mesoporous, and nanostructure AC materials. These characteristics of AC materials are necessary for the low energy and efficient photocatalytic system. Due to the excellent oxidizing characteristics, cheapness, and long-term stability, semiconductor materials have been used immensely in photocatalytic reactors. However, in practical, such conductors lead to problems with the separation steps and loss of photocatalytic activity. Therefore, proper attention has been given to develop supported semiconductor catalysts and certain matrixes of carbon materials such as carbon nanotubes, carbon microspheres, carbon nanofibers, carbon black, and activated carbons have been recently considered and reported. AC has been reported as a potential support in photocatalytic systems because it improves the transfer rate of the interface charge and lowers the recombination rate of holes and electrons.

  1. Persuasive Technology in Mobile Applications Promoting Physical Activity: a Systematic Review. (United States)

    Matthews, John; Win, Khin Than; Oinas-Kukkonen, Harri; Freeman, Mark


    Persuasive technology in mobile applications can be used to influence the behaviour of users. A framework known as the Persuasive Systems Design model has been developed for designing and evaluating systems that influence the attitudes or behaviours of users. This paper reviews the current state of mobile applications for health behavioural change with an emphasis on applications that promote physical activity. The inbuilt persuasive features of mobile applications were evaluated using the Persuasive Systems Design model. A database search was conducted to identify relevant articles. Articles were then reviewed using the Persuasive Systems Design model as a framework for analysis. Primary task support, dialogue support, and social support were found to be moderately represented in the selected articles. However, system credibility support was found to have only low levels of representation as a persuasive systems design feature in mobile applications for supporting physical activity. To ensure that available mobile technology resources are best used to improve the wellbeing of people, it is important that the design principles that influence the effectiveness of persuasive technology be understood.

  2. Performance Measurement and Analysis of Large-Scale Parallel Applications on Leadership Computing Systems

    Directory of Open Access Journals (Sweden)

    Brian J.N. Wylie


    Full Text Available Developers of applications with large-scale computing requirements are currently presented with a variety of high-performance systems optimised for message-passing, however, effectively exploiting the available computing resources remains a major challenge. In addition to fundamental application scalability characteristics, application and system peculiarities often only manifest at extreme scales, requiring highly scalable performance measurement and analysis tools that are convenient to incorporate in application development and tuning activities. We present our experiences with a multigrid solver benchmark and state-of-the-art real-world applications for numerical weather prediction and computational fluid dynamics, on three quite different multi-thousand-processor supercomputer systems – Cray XT3/4, MareNostrum & Blue Gene/L – using the newly-developed SCALASCA toolset to quantify and isolate a range of significant performance issues.

  3. Application of multivariate data analysis for identification and successful resolution of a root cause for a bioprocessing application. (United States)

    Kirdar, Alime Ozlem; Green, Ken D; Rathore, Anurag S


    Multivariate Data Analysis (MVDA) can be used for supporting key activities required for successful bioprocessing. These activities include process characterization, process scale-up, process monitoring, fault diagnosis and root cause analysis. This paper examines an application of MVDA towards root cause analysis for identifying scale-up differences and parameter interactions that adversely impact cell culture process performance. Multivariate data analysis and modeling were performed using data from small-scale (2 L), pilot-scale (2,000 L) and commercial-scale (15,000 L) batches. The input parameters examined included bioreactor pCO2, glucose, lactate, ammonium, raw materials and seed inocula. The output parameters included product attributes, product titer, viable cell density, cell viability and osmolality. Time course performance variables (daily, initial, peak and end point) were also evaluated. Application of MVDA as a diagnostic tool was successful in identifying the root cause and designing experimental conditions to demonstrate and correct it. Process parameters and their interactions that adversely impact cell culture performance and product attributes were successfully identified. MVDA was successfully used as an effective tool for collating process knowledge and increasing process understanding.

  4. Use of application containers and workflows for genomic data analysis

    Directory of Open Access Journals (Sweden)

    Wade L Schulz


    Full Text Available Background: The rapid acquisition of biological data and development of computationally intensive analyses has led to a need for novel approaches to software deployment. In particular, the complexity of common analytic tools for genomics makes them difficult to deploy and decreases the reproducibility of computational experiments. Methods: Recent technologies that allow for application virtualization, such as Docker, allow developers and bioinformaticians to isolate these applications and deploy secure, scalable platforms that have the potential to dramatically increase the efficiency of big data processing. Results: While limitations exist, this study demonstrates a successful implementation of a pipeline with several discrete software applications for the analysis of next-generation sequencing (NGS data. Conclusions: With this approach, we significantly reduced the amount of time needed to perform clonal analysis from NGS data in acute myeloid leukemia.

  5. Hyperbolic Conservation Laws and Related Analysis with Applications

    CERN Document Server

    Holden, Helge; Karlsen, Kenneth


    This book presents thirteen papers, representing the most significant advances and current trends in nonlinear hyperbolic conservation laws and related analysis with applications. Topics covered include a survey on multidimensional systems of conservation laws as well as novel results  on liquid crystals, conservation laws with discontinuous flux functions, and applications to sedimentation.  Also included are articles on recent advances in the Euler equations and the Navier-Stokes-Fourier-Poisson system, in addition to new results on collective phenomena described by the Cucker-Smale model.    The Workshop on Hyperbolic Conservation Laws and Related Analysis with Applications at the International Centre for Mathematical Sciences (Edinburgh, UK) held in Edinburgh, September 2011, produced this fine collection of original research and survey articles. Many leading mathematicians attended the event and submitted their contributions for this volume. It is addressed to researchers and graduate students inter...

  6. An introduction to queueing theory modeling and analysis in applications

    CERN Document Server

    Bhat, U Narayan


    This introductory textbook is designed for a one-semester course on queueing theory that does not require a course on stochastic processes as a prerequisite. By integrating the necessary background on stochastic processes with the analysis of models, the work provides a sound foundational introduction to the modeling and analysis of queueing systems for a wide interdisciplinary audience of students in mathematics, statistics, and applied disciplines such as computer science, operations research, and engineering. This edition includes additional topics in methodology and applications. Key features: • An introductory chapter including a historical account of the growth of queueing theory in more than 100 years. • A modeling-based approach with emphasis on identification of models. • Rigorous treatment of the foundations of basic models commonly used in applications with appropriate references for advanced topics. • Applications in manufacturing and, computer and communication systems. • A chapter on ...

  7. Wavelet Transforms: Application to Data Analysis-I

    Indian Academy of Sciences (India)

    ... Lecture Workshops · Refresher Courses · Symposia. Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 11. Wavelet Transforms: Application to Data Analysis – I. Jatan K Modi Sachin P Nanavati Amit S Phadke Prasanta K Panigrahi. General Article Volume 9 Issue 11 November 2004 pp 10-22 ...

  8. Application of Kissinger analysis to glass transition and study of ...

    Indian Academy of Sciences (India)

    Mater. Sci., Vol. 35, No. 4, August 2012, pp. 657–664. c Indian Academy of Sciences. Application of Kissinger analysis to glass transition and study of thermal degradation kinetics of phenolic–acrylic IPNs. S GOSWAMI. ∗ and K KIRAN. Department of Polymer Engineering, Birla Institute of Technology, Ranchi 835 215, India.

  9. application of the reissners plate theory in the delamination analysis ...

    African Journals Online (AJOL)

    Dr Obe


  10. Application of Intermittent Microwave Irradiation to Western Blot Analysis. (United States)

    Liu, Yu-Ting; Toyokuni, Shinya


    We established a shortened protocol for Western blot analysis using intermittent microwave irradiation. With this method, the procedure is completed within 1 h after applying the primary antibody, and thus greatly saves time. This procedure appears to be applicable to any antibody based on our experience of several years.

  11. Applications of computer-aided text analysis in natural resources. (United States)

    David N. Bengston


    Ten contributed papers describe the use of a variety of approaches to computer-aided text analysis and their application to a wide range of research questions related to natural resources and the environment. Taken together, these papers paint a picture of a growing and vital area of research on the human dimensions of natural resource management.

  12. Multi-commutation in flow analysis: recent developments and applications. (United States)

    Feres, Mário A; Fortes, Paula R; Zagatto, Elias A G; Santos, João L M; Lima, José L F C


    The concept of multi-commutation in flow analysis is revisited, and emphasis is given to recent methodological and applicative achievements. Multi-commutation is compatible with different flow patterns (unsegmented, segmented, pulsed, tandem) and amenable to concentration-oriented feedback mechanisms. Its exploitation has led to significant attainments mainly in relation to versatility of the flow system. Characteristics and potentialities of the multi-commuted flow systems are discussed, and guidelines for assisting methodological implementation are given. The number of applications has experienced remarkable increase during last years; therefore, the applicative part of this review is focused on the recent noteworthy applications, mainly in relation to environmental, agronomical, pharmaceutical, biological, food and industrial samples.

  13. Active Sensing and Its Application to Sensor Node Reconfiguration

    Directory of Open Access Journals (Sweden)

    Sooyong Lee


    Full Text Available This paper presents a perturbation/correlation-based active sensing method and its application to sensor node configuration for environment monitoring. Sensor networks are widely used as data measurement tools, especially in dangerous environments. For large scale environment monitoring, a large number of nodes is required. For optimal measurements, the placement of nodes is very important. Nonlinear spring force-based configuration is introduced. Perturbation/correlation-based estimation of the gradient is developed and it is much more robust because it does not require any differentiation. An algorithm for tuning the stiffness using the estimated gradient for node reconfiguration is presented. The performance of the proposed algorithm is discussed with simulation results.

  14. Applications of adaptive filters in active noise control (United States)

    Darlington, Paul

    The active reduction of acoustic noise is achieved by the addition of a cancelling acoustic signal to the unwanted sound. Successful definition of the cancelling signal amounts to a system identification problem. Recent advances in adaptive signal processing have allowed this problem to be tackled using adaptive filters, which offer significant advantages over conventional solutions. The extension of adaptive noise cancelling techniques, which were developed in the electrical signal conditioning context, to the control of acoustic systems is studied. An analysis is presented of the behavior of the Widrow-Hoff LMS adaptive noise canceller with a linear filter in its control loop. The active control of plane waves propagating axially in a hardwalled duct is used as a motivating model problem. The model problem also motivates the study of the effects of feedback around an LMS adaptive filter. An alternative stochastic gradient algorithm for controlling adaptive filters in the presence of feedback is presented.


    Energy Technology Data Exchange (ETDEWEB)

    Schweitzer, Martin [ORNL


    Between 2001 and 2005, the U.S. Department of Energy (DOE) created a set of eight Regional Application Centers (RACs) to facilitate the development and deployment of Combined Heat and Power (CHP) technologies. By utilizing the thermal energy that is normally wasted when electricity is produced at central generating stations, Combined Heat and Power installations can save substantial amounts of energy compared to more traditional technologies. In addition, the location of CHP facilities at or near the point of consumption greatly reduces or eliminates electric transmission and distribution losses. The regional nature of the RACs allows each one to design and provide services that are most relevant to the specific economic and market conditions in its particular geographic area. Between them, the eight RACs provide services to all 50 states and the District of Columbia. Through the end of the federal 2009 fiscal year (FY 2009), the primary focus of the RACs was on providing CHP-related information to targeted markets, encouraging the creation and adoption of public policies and incentives favorable to CHP, and providing CHP users and prospective users with technical assistance and support on specific projects. Beginning with the 2010 fiscal year, the focus of the regional centers broadened to include district energy and waste heat recovery and these entities became formally known as Clean Energy Application Centers, as required by the Energy Independence and Security Act (EISA) of 2007. In 2007, ORNL led a cooperative effort to establish metrics to quantify the RACs accomplishments. That effort began with the development of a detailed logic model describing RAC operations and outcomes, which provided a basis for identifying important activities and accomplishments to track. A data collection spreadsheet soliciting information on those activities for FY 2008 and all previous years of RAC operations was developed and sent to the RACs in the summer of 2008. This

  16. Active Wireless System for Structural Health Monitoring Applications. (United States)

    Perera, Ricardo; Pérez, Alberto; García-Diéguez, Marta; Zapico-Valle, José Luis


    The use of wireless sensors in Structural Health Monitoring (SHM) has increased significantly in the last years. Piezoelectric-based lead zirconium titanate (PZT) sensors have been on the rise in SHM due to their superior sensing abilities. They are applicable in different technologies such as electromechanical impedance (EMI)-based SHM. This work develops a flexible wireless smart sensor (WSS) framework based on the EMI method using active sensors for full-scale and autonomous SHM. In contrast to passive sensors, the self-sensing properties of the PZTs allow interrogating with or exciting a structure when desired. The system integrates the necessary software and hardware within a service-oriented architecture approach able to provide in a modular way the services suitable to satisfy the key requirements of a WSS. The framework developed in this work has been validated on different experimental applications. Initially, the reliability of the EMI method when carried out with the proposed wireless sensor system is evaluated by comparison with the wireless counterpart. Afterwards, the performance of the system is evaluated in terms of software stability and reliability of functioning.

  17. Active learning in camera calibration through vision measurement application (United States)

    Li, Xiaoqin; Guo, Jierong; Wang, Xianchun; Liu, Changqing; Cao, Binfang


    Since cameras are increasingly more used in scientific application as well as in the applications requiring precise visual information, effective calibration of such cameras is getting more important. There are many reasons why the measurements of objects are not accurate. The largest reason is that the lens has a distortion. Another detrimental influence on the evaluation accuracy is caused by the perspective distortions in the image. They happen whenever we cannot mount the camera perpendicularly to the objects we want to measure. In overall, it is very important for students to understand how to correct lens distortions, that is camera calibration. If the camera is calibrated, the images are rectificated, and then it is possible to obtain undistorted measurements in world coordinates. This paper presents how the students should develop a sense of active learning for mathematical camera model besides the theoretical scientific basics. The authors will present the theoretical and practical lectures which have the goal of deepening the students understanding of the mathematical models of area scan cameras and building some practical vision measurement process by themselves.

  18. Active Wireless System for Structural Health Monitoring Applications

    Directory of Open Access Journals (Sweden)

    Ricardo Perera


    Full Text Available The use of wireless sensors in Structural Health Monitoring (SHM has increased significantly in the last years. Piezoelectric-based lead zirconium titanate (PZT sensors have been on the rise in SHM due to their superior sensing abilities. They are applicable in different technologies such as electromechanical impedance (EMI-based SHM. This work develops a flexible wireless smart sensor (WSS framework based on the EMI method using active sensors for full-scale and autonomous SHM. In contrast to passive sensors, the self-sensing properties of the PZTs allow interrogating with or exciting a structure when desired. The system integrates the necessary software and hardware within a service-oriented architecture approach able to provide in a modular way the services suitable to satisfy the key requirements of a WSS. The framework developed in this work has been validated on different experimental applications. Initially, the reliability of the EMI method when carried out with the proposed wireless sensor system is evaluated by comparison with the wireless counterpart. Afterwards, the performance of the system is evaluated in terms of software stability and reliability of functioning.

  19. Intruder Activity Analysis under Unreliable Sensor Networks

    Energy Technology Data Exchange (ETDEWEB)

    Tae-Sic Yoo; Humberto E. Garcia


    This paper addresses the problem of counting intruder activities within a monitored domain by a sensor network. The deployed sensors are unreliable. We characterize imperfect sensors with misdetection and false-alarm probabilities. We model intruder activities with Markov Chains. A set of Hidden Markov Models (HMM) models the imperfect sensors and intruder activities to be monitored. A novel sequential change detection/isolation algorithm is developed to detect and isolate a change from an HMM representing no intruder activity to another HMM representing some intruder activities. Procedures for estimating the entry time and the trace of intruder activities are developed. A domain monitoring example is given to illustrate the presented concepts and computational procedures.

  20. Modern Era Retrospective-Analysis for Research and Applications (United States)

    Bosilovich, Michael G.; Robertson, Franklin R.; Chen, Junye


    The Modern Era Retrospective-analysis for Research and Applications (MERRA) reanalyses has produced several years of data, on the way to a. completing the 1979-present modern satellite era. Here, we present a preliminary evaluation of those years currently available, including comparisons with the existing long reanalyses (ERA40, JPA25 and NCEP I and II) as well as with global data sets for the water and energy cycle. Time series shows that the MERRA budgets can change with some of the variations in observing systems. We will present all terms of the budgets in MERRA including the time rates of change and analysis increments (tendency due to the analysis of observations).

  1. Linear functional analysis an application-oriented introduction

    CERN Document Server

    Alt, Hans Wilhelm


    This book gives an introduction to Linear Functional Analysis, a synthesis of algebra, topology, and analysis. In addition to the basic theory it explains operator theory, distributions, Sobolev spaces, and many other things. The text is self-contained and includes all proofs, as well as many exercises, most of them with solutions. Moreover, there are a number of appendices, for example on Lebesgue integration theory. A complete introduction to the subject, Linear Functional Analysis will be particularly useful to readers who want to quickly get to the key statements and who are interested in applications to differential equations.

  2. Applications of a broad-spectrum tool for conservation and fisheries analysis: aquatic gap analysis (United States)

    McKenna, James E.; Steen, Paul J.; Lyons, John; Stewart, Jana S.


    Natural resources support all of our social and economic activities, as well as our biological existence. Humans have little control over most of the physical, biological, and sociological conditions dictating the status and capacity of natural resources in any particular area. However, the most rapid and threatening influences on natural resources typically are anthropogenic overuse and degradation. In addition, living natural resources (i.e., organisms) do not respect political boundaries, but are aware of their optimal habitat and environmental conditions. Most organisms have wider spatial ranges than the jurisdictional boundaries of environmental agencies that deal with them; even within those jurisdictions, information is patchy and disconnected. Planning and projecting effects of ecological management are difficult, because many organisms, habitat conditions, and interactions are involved. Conservation and responsible resource use involves wise management and manipulation of the aspects of the environment and biological communities that can be effectively changed. Tools and data sets that provide new insights and analysis capabilities can enhance the ability of resource managers to make wise decisions and plan effective, long-term management strategies. Aquatic gap analysis has been developed to provide those benefits. Gap analysis is more than just the assessment of the match or mis-match (i.e., gaps) between habitats of ecological value and areas with an appropriate level of environmental protection (e.g., refuges, parks, preserves), as the name suggests. Rather, a Gap Analysis project is a process which leads to an organized database of georeferenced information and previously available tools to examine conservation and other ecological issues; it provides a geographic analysis platform that serves as a foundation for aquatic ecological studies. This analytical tool box allows one to conduct assessments of all habitat elements within an area of interest

  3. Audio visual information fusion for human activity analysis


    Thagadur Shivappa, Shankar


    Human activity analysis in unconstrained environments using far-field sensors is a challenging task. The fusion of audio and visual cues enables us to build robust and efficient human activity analysis systems. Traditional fusion schemes including feature-level, classifier-level and decision-level fusion have been explored in task- specific contexts to provide robustness to sensor and environmental noise. However, human activity analysis involves the extraction of information from audio and v...

  4. Neutron activation analysis of wheat samples

    Energy Technology Data Exchange (ETDEWEB)

    Galinha, C. [CERENA-IST, Technical University of Lisbon, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); Instituto Tecnoclogico e Nuclear, URSN, E.N. 10, 2686-953 Sacavem (Portugal); Anawar, H.M. [Instituto Tecnoclogico e Nuclear, URSN, E.N. 10, 2686-953 Sacavem (Portugal); Freitas, M.C., E-mail: [Instituto Tecnoclogico e Nuclear, URSN, E.N. 10, 2686-953 Sacavem (Portugal); Pacheco, A.M.G. [CERENA-IST, Technical University of Lisbon, Av. Rovisco Pais 1, 1049-001 Lisboa (Portugal); Almeida-Silva, M. [Instituto Tecnoclogico e Nuclear, URSN, E.N. 10, 2686-953 Sacavem (Portugal); Coutinho, J.; Macas, B.; Almeida, A.S. [INRB/INIA-Elvas, National Institute of Biological Resources, Est. Gil Vaz, 7350-228 Elvas (Portugal)


    The deficiency of essential micronutrients and excess of toxic metals in cereals, an important food items for human nutrition, can cause public health risk. Therefore, before their consumption and adoption of soil supplementation, concentrations of essential micronutrients and metals in cereals should be monitored. This study collected soil and two varieties of wheat samples-Triticum aestivum L. (Jordao/bread wheat), and Triticum durum L. (Marialva/durum wheat) from Elvas area, Portugal and analyzed concentrations of As, Cr, Co, Fe, K, Na, Rb and Zn using Instrumental Neutron Activation Analysis (INAA) to focus on the risk of adverse public health issues. The low variability and moderate concentrations of metals in soils indicated a lower significant effect of environmental input on metal concentrations in agricultural soils. The Cr and Fe concentrations in soils that ranged from 93-117 and 26,400-31,300 mg/kg, respectively, were relatively high, but Zn concentration was very low (below detection limit <22 mg/kg) indicating that soils should be supplemented with Zn during cultivation. The concentrations of metals in roots and straw of both varieties of wheat decreased in the order of K>Fe>Na>Zn>Cr>Rb>As>Co. Concentrations of As, Co and Cr in root, straw and spike of both varieties were higher than the permissible limits with exception of a few samples. The concentrations of Zn in root, straw and spike were relatively low (4-30 mg/kg) indicating the deficiency of an essential micronutrient Zn in wheat cultivated in Portugal. The elemental transfer from soil to plant decreases with increasing growth of the plant. The concentrations of various metals in different parts of wheat followed the order: Root>Straw>Spike. A few root, straw and spike samples showed enrichment of metals, but the majority of the samples showed no enrichment. Potassium is enriched in all samples of root, straw and spike for both varieties of wheat. Relatively to the seed used for cultivation

  5. Application and Analysis of a Cross-Over Design

    Directory of Open Access Journals (Sweden)

    Clive J. Lawrence


    Full Text Available In this paper we consider the application and analysis of a cross-over design in a medical problem. Some statistical detail is given of the linear model used and its analysis. This design is in the class of repeated measurement analyses which can, for the medical research worker, be a source of some difficulty. Its application to a study of the constituents of breast-milk, and their possible variation between hand and pump expression is examined. Data for this analysis comes from a study that has been carried out in Exeter, UK, in which information was collected on a number of different aspects of infant feeding. Results for sodium, potassium, and other constituents are reported, together with some discussion of the various practical difficulties that can arise in the organisation of studies of this kind. Comments are included concerning the extension from two to three-period designs, and in the testing of significance.

  6. Karyotype Analysis Activity: A Constructivist Learning Design (United States)

    Ahmed, Noveera T.


    This classroom activity is based on a constructivist learning design and engages students in physically constructing a karyotype of three mock patients. Students then diagnose the chromosomal aneuploidy based on the karyotype, list the symptoms associated with the disorder, and discuss the implications of the diagnosis. This activity is targeted…

  7. An Energy and Application Scenario Aware Active RFID Protocol

    Directory of Open Access Journals (Sweden)

    Nilsson Björn


    Full Text Available The communication protocol used is a key issue in order to make the most of the advantages of active RFID technologies. In this paper we introduce a carrier sense medium access data communication protocol that dynamically adjusts its back-off algorithm to best suit the actual application at hand. Based on a simulation study of the effect on tag energy cost, read-out delay, and message throughput incurred by some typical back-off algorithms in a CSMA/CA (Carrier Sense Multiple Access/Collision Avoidance active RFID protocol, we conclude that by dynamic tuning of the initial contention window size and back-off interval coefficient, tag energy consumption and read-out delay can be significantly lowered. We show that it is possible to decrease the energy consumption per tag payload delivery with more than 10 times, resulting in a 50% increase in tag battery lifetime. We also discuss the advantage of being able to predict the number of tags present at the RFID-reader as well as ways of doing it.

  8. Active C4 Electrodes for Local Field Potential Recording Applications. (United States)

    Wang, Lu; Freedman, David; Sahin, Mesut; Ünlü, M Selim; Knepper, Ronald


    Extracellular neural recording, with multi-electrode arrays (MEAs), is a powerful method used to study neural function at the network level. However, in a high density array, it can be costly and time consuming to integrate the active circuit with the expensive electrodes. In this paper, we present a 4 mm × 4 mm neural recording integrated circuit (IC) chip, utilizing IBM C4 bumps as recording electrodes, which enable a seamless active chip and electrode integration. The IC chip was designed and fabricated in a 0.13 μm BiCMOS process for both in vitro and in vivo applications. It has an input-referred noise of 4.6 μV rms for the bandwidth of 10 Hz to 10 kHz and a power dissipation of 11.25 mW at 2.5 V, or 43.9 μW per input channel. This prototype is scalable for implementing larger number and higher density electrode arrays. To validate the functionality of the chip, electrical testing results and acute in vivo recordings from a rat barrel cortex are presented.

  9. RADSAT Benchmarks for Prompt Gamma Neutron Activation Analysis Measurements

    Energy Technology Data Exchange (ETDEWEB)

    Burns, Kimberly A.; Gesh, Christopher J.


    The accurate and efficient simulation of coupled neutron-photon problems is necessary for several important radiation detection applications. Examples include the detection of nuclear threats concealed in cargo containers and prompt gamma neutron activation analysis for nondestructive determination of elemental composition of unknown samples. High-resolution gamma-ray spectrometers are used in these applications to measure the spectrum of the emitted photon flux, which consists of both continuum and characteristic gamma rays with discrete energies. Monte Carlo transport is the most commonly used simulation tool for this type of problem, but computational times can be prohibitively long. This work explores the use of multi-group deterministic methods for the simulation of coupled neutron-photon problems. The main purpose of this work is to benchmark several problems modeled with RADSAT and MCNP to experimental data. Additionally, the cross section libraries for RADSAT are updated to include ENDF/B-VII cross sections. Preliminary findings show promising results when compared to MCNP and experimental data, but also areas where additional inquiry and testing are needed. The potential benefits and shortcomings of the multi-group-based approach are discussed in terms of accuracy and computational efficiency.

  10. Probabilistic safety analysis of external floods. Method and application

    Energy Technology Data Exchange (ETDEWEB)

    Kluegel, J.U. [Kernkraftwerk Goesgen-Daeniken (Switzerland)


    The events of Fukushima amplified the scientific interest in the improvement of methods for probabilistic safety assessment (PSA) of extreme external events. The assessment of consequences of external floods belongs to this group of events. The paper presents the key steps of methodology for probabilistic safety assessment of external floods and a recent application for a nuclear power plant in Switzerland. The presented methodology is an extension of earlier activities and provides more focus on the PSA methodology part that may be applicable also for other studies. (orig.)

  11. [Applications of meta-analysis in multi-omics]. (United States)

    Han, Mingfei; Zhu, Yunping


    As a statistical method integrating multi-features and multi-data, meta-analysis was introduced to the field of life science in the 1990s. With the rapid advances in high-throughput technologies, life omics, the core of which are genomics, transcriptomics and proteomics, is becoming the new hot spot of life science. Although the fast output of massive data has promoted the development of omics study, it results in excessive data that are difficult to integrate systematically. In this case, meta-analysis is frequently applied to analyze different types of data and is improved continuously. Here, we first summarize the representative meta-analysis methods systematically, and then study the current applications of meta-analysis in various omics fields, finally we discuss the still-existing problems and the future development of meta-analysis.

  12. Variational analysis of regular mappings theory and applications

    CERN Document Server

    Ioffe, Alexander D


    This monograph offers the first systematic account of (metric) regularity theory in variational analysis. It presents new developments alongside classical results and demonstrates the power of the theory through applications to various problems in analysis and optimization theory. The origins of metric regularity theory can be traced back to a series of fundamental ideas and results of nonlinear functional analysis and global analysis centered around problems of existence and stability of solutions of nonlinear equations. In variational analysis, regularity theory goes far beyond the classical setting and is also concerned with non-differentiable and multi-valued operators. The present volume explores all basic aspects of the theory, from the most general problems for mappings between metric spaces to those connected with fairly concrete and important classes of operators acting in Banach and finite dimensional spaces. Written by a leading expert in the field, the book covers new and powerful techniques, whic...

  13. Detailed Analysis of Motor Unit Activity

    DEFF Research Database (Denmark)

    Nikolic, Mile; Sørensen, John Aasted; Dahl, Kristian


    System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability.......System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability....

  14. Testing the applicability of rapid on-site enzymatic activity detection for surface water monitoring (United States)

    Stadler, Philipp; Vogl, Wolfgang; Juri, Koschelnik; Markus, Epp; Maximilian, Lackner; Markus, Oismüller; Monika, Kumpan; Peter, Strauss; Regina, Sommer; Gabriela, Ryzinska-Paier; Farnleitner Andreas, H.; Matthias, Zessner


    On-site detection of enzymatic activities has been suggested as a rapid surrogate for microbiological pollution monitoring of water resources (e.g. using glucuronidases, galactosidases, esterases). Due to the possible short measuring intervals enzymatic methods have high potential as near-real time water quality monitoring tools. This presentation describes results from a long termed field test. For twelve months, two ColiMinder devices (Vienna Water Monitoring, Austria) for on-site determination of enzymatic activity were tested for stream water monitoring at the experimental catchment HOAL (Hydrological Open Air Laboratory, Center for Water Resource Systems, Vienna University of Technology). The devices were overall able to follow and reflect the diverse hydrological and microbiological conditions of the monitored stream during the test period. Continuous data in high temporal resolution captured the course of enzymatic activity in stream water during diverse rainfall events. The method also proofed sensitive enough to determine diurnal fluctuations of enzymatic activity in stream water during dry periods. The method was able to capture a seasonal trend of enzymatic activity in stream water that matches the results gained from Colilert18 analysis for E. coli and coliform bacteria of monthly grab samples. Furthermore the comparison of ColiMinder data with measurements gained at the same test site with devices using the same method but having different construction design (BACTcontrol, microLAN) showed consistent measuring results. Comparative analysis showed significant differences between measured enzymatic activity (modified fishman units and pmol/min/100ml) and cultivation based analyses (most probable number, colony forming unit). Methods of enzymatic activity measures are capable to detect ideally the enzymatic activity caused by all active target bacteria members, including VBNC (viable but nonculturable) while cultivation based methods cannot detect VBNC

  15. Complex analysis with applications to flows and fields

    CERN Document Server

    Braga da Costa Campos, Luis Manuel


    Complex Analysis with Applications to Flows and Fields presents the theory of functions of a complex variable, from the complex plane to the calculus of residues to power series to conformal mapping. The book explores numerous physical and engineering applications concerning potential flows, the gravity field, electro- and magnetostatics, steady heat conduction, and other problems. It provides the mathematical results to sufficiently justify the solution of these problems, eliminating the need to consult external references.The book is conveniently divided into four parts. In each part, the ma

  16. Polyglot programming in applications used for genetic data analysis. (United States)

    Nowak, Robert M


    Applications used for the analysis of genetic data process large volumes of data with complex algorithms. High performance, flexibility, and a user interface with a web browser are required by these solutions, which can be achieved by using multiple programming languages. In this study, I developed a freely available framework for building software to analyze genetic data, which uses C++, Python, JavaScript, and several libraries. This system was used to build a number of genetic data processing applications and it reduced the time and costs of development.

  17. Technology for application family creation based on domain analysis




    The theme of code reuse in software development is still important. Sometimes it is hard to find out what exactly we need to reuse in isolation of context. However, there is an opportunity to narrow the context problem, if applications in one given domain are considered. Same features in different applications in one domain have the same context respectively so the common part must be reused. Hence, the problem of domain analysis arises. On the other hand, there is metaCASE-techonology that a...

  18. Multivariate time series analysis with R and financial applications

    CERN Document Server

    Tsay, Ruey S


    Since the publication of his first book, Analysis of Financial Time Series, Ruey Tsay has become one of the most influential and prominent experts on the topic of time series. Different from the traditional and oftentimes complex approach to multivariate (MV) time series, this sequel book emphasizes structural specification, which results in simplified parsimonious VARMA modeling and, hence, eases comprehension. Through a fundamental balance between theory and applications, the book supplies readers with an accessible approach to financial econometric models and their applications to real-worl

  19. The Applicability of the Risk Analysis System in Tax Audit Effectiveness (A Sample Application on Gaziantep Carpet Sector

    Directory of Open Access Journals (Sweden)

    Atilla Ahmet UĞUR


    Full Text Available Tax audit which is an undeniable part of the correct collection of taxes covering a significant portion of public expenditure is increasingly important in our tax where the basis of the declaration is valid. The necessity of tax audit to be effective is accepted by everyone without a doubt, but the issue of efficiency in tax audit has always been a problem. The effectiveness of tax audit is increasingly important in terms of the fiscal policy of the country and therefore of general economic policy. Various options have been put forward on ways to improve the efficiency of tax audit. One of these options is the risk analysis method. Risk analysis is an activity in which taxpayer's activities are analyzed in terms of groups and sectors through the risk analysis system which is formed by collecting all kind of information data and statistics and it is the activity to identify risk areas in this way. In this sense this study addresses a sample application of the risk analysis system for the Gaziantep Carpet Sector.

  20. Soil microbial communities and enzyme activities under various poultry litter application rates. (United States)

    Acosta-Martínez, V; Harmel, R Daren


    The potential excessive nutrient and/or microbial loading from mismanaged land application of organic fertilizers is forcing changes in animal waste management. Currently, it is not clear to what extent different rates of poultry litter impact soil microbial communities, which control nutrient availability, organic matter quality and quantity, and soil degradation potential. From 2002 to 2004, we investigated the microbial community and several enzyme activities in a Vertisol soil (fine, smectitic, thermic, Udic Haplustert) at 0 to 15 cm as affected by different rates of poultry litter application to pasture (0, 6.7, and 13.4 Mg ha(-1)) and cultivated sites (0, 4.5, 6.7, 9.0, 11.2, and 13.4 Mg ha(-1)) in Texas, USA. No differences in soil pH (average: 7.9), total N (pasture: 2.01-3.53, cultivated: 1.09-1.98 g kg(-1) soil) or organic C (pasture average: 25-26.7, cultivated average: 13.9-16.1 g kg(-1) soil) were observed following the first four years of litter application. Microbial biomass carbon (MBC) and nitrogen (MBN) increased at litter rates greater than 6.7 Mg ha(-1) (pasture: MBC = >863, MBN = >88 mg kg(-1) soil) compared to sites with no applied litter (MBC = 722, MBN = 69 mg kg(-1) soil). Enzyme activities of C (beta-glucosidase, alpha-galactosidase, beta-glucosaminidase) or N cycling (beta-glucosaminidase) were increased at litter rates greater than 6.7 Mg ha(-1). Enzyme activities of P (alkaline phosphatase) and S (arylsulfatase) mineralization showed the same response in pasture, but they were only increased at the highest (9.0, 11.2, and 13.4 Mg ha(-1)) litter application rates in cultivated sites. According to fatty acid methyl ester (FAME) analysis, the pasture soils experienced shifts to higher bacterial populations at litter rates of 6.7 Mg ha(-1), and shifts to higher fungal populations at the highest litter application rates in cultivated sites. While rates greater than 6.7 Mg ha(-1) provided rapid enhancement of the soil microbial populations

  1. Activated carbon derived from rice husk by NaOH activation and its application in supercapacitor

    Directory of Open Access Journals (Sweden)

    Khu Le Van


    Full Text Available Four activated carbon (AC samples prepared from rice husk under different activation temperatures have been characterized by N2 adsorption–desorption isotherms, thermogravimetric analysis (TGA–DTA, Fourier transform infrared spectroscopy (FTIR and scanning electron microscopy (SEM. The specific surface area of AC sample reached 2681 m2 g−1 under activation temperature of 800 °C. The AC samples were then tested as electrode material; the specific capacitance of the as-prepared activated carbon electrode was found to be 172.3 F g−1 using cyclic voltammetry at a scan rate of 5 mV s−1 and 198.4 F g−1 at current density 1000 mA g−1 in the charge/discharge mode.

  2. Direct analysis in real time-Mass spectrometry (DART-MS) in forensic and security applications. (United States)

    Pavlovich, Matthew J; Musselman, Brian; Hall, Adam B


    Over the last decade, direct analysis in real time (DART) has emerged as a viable method for fast, easy, and reliable "ambient ionization" for forensic analysis. The ability of DART to generate ions from chemicals that might be present at the scene of a criminal activity, whether they are in the gas, liquid, or solid phase, with limited sample preparation has made the technology a useful analytical tool in numerous forensic applications. This review paper summarizes many of those applications, ranging from the analysis of trace evidence to security applications, with a focus on providing the forensic scientist with a resource for developing their own applications. The most common uses for DART in forensics are in studying seized drugs, drugs of abuse and their metabolites, bulk and detonated explosives, toxic chemicals, chemical warfare agents, inks and dyes, and commercial plant and animal products that have been adulterated for economic gain. This review is meant to complement recent reviews that have described the fundamentals of the ionization mechanism and the general use of DART. We describe a wide range of forensic applications beyond the field of analyzing drugs of abuse, which dominates the literature, including common experimental and data analysis methods. © 2016 Wiley Periodicals, Inc. Mass Spec Rev 37:171-187, 2018. © 2016 Wiley Periodicals, Inc.

  3. Applications of nuclear technologies for in-vivo elemental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cohn, S.H.; Ellis, K.J.; Vartsky, D.; Wielopolski, L.


    Measurement facilities developed, to date, include a unique whole-body-counter, (WBC); a total-body neutron-activation facility (TBNAA); and a partial-body activation facility (PBNAA). A variation of the prompt-gamma neutron-activation technique for measuring total-body nitrogen was developed to study body composition of cancer patients and the effect of nutritional regimens on the composition. These new techniques provide data in numerous clinical studies not previously amenable to investigation. The development and perfection of these techniques provide unique applications of radiation and radioisotopes to the early diagnosis of certain diseases and the evaluation of therapeutic programs. The PBNAA technique has been developed and calibrated for in-vivo measurement of metals. Development has gone forward on prompt-gamma neutron activation for the measurement of cadmium, x-ray fluorescence (XRF) for measurement of iron. Other techniques are being investigated for in-vivo measurement of metals such as silicon and beryllium.

  4. A Unified Framework for Activity Recognition-Based Behavior Analysis and Action Prediction in Smart Homes

    Directory of Open Access Journals (Sweden)

    Sungyoung Lee


    Full Text Available In recent years, activity recognition in smart homes is an active research area due to its applicability in many applications, such as assistive living and healthcare. Besides activity recognition, the information collected from smart homes has great potential for other application domains like lifestyle analysis, security and surveillance, and interaction monitoring. Therefore, discovery of users common behaviors and prediction of future actions from past behaviors become an important step towards allowing an environment to provide personalized service. In this paper, we develop a unified framework for activity recognition-based behavior analysis and action prediction. For this purpose, first we propose kernel fusion method for accurate activity recognition and then identify the significant sequential behaviors of inhabitants from recognized activities of their daily routines. Moreover, behaviors patterns are further utilized to predict the future actions from past activities. To evaluate the proposed framework, we performed experiments on two real datasets. The results show a remarkable improvement of 13.82% in the accuracy on average of recognized activities along with the extraction of significant behavioral patterns and precise activity predictions with 6.76% increase in F-measure. All this collectively help in understanding the users” actions to gain knowledge about their habits and preferences.

  5. Final Report 02-ERD-056 Active Load Control& Mitigation Using Microtabs: A Wind Energy Application

    Energy Technology Data Exchange (ETDEWEB)

    Nakafuji, D Y


    With public concern over the security and reliability of our existing electricity infrastructure and the resurgence of wind energy, the wind industry offers an immediate, first point of entry for the application and demonstration of an active load control technology. An innovative microtab approach is being investigated and demonstrated for active aerodynamic load control applications under the mid-year LDRD (June-Sept. 2002) effort. With many of these million dollar turbines failing at only half the design lifespans, conventional techniques for stiffening rotors, enlarging generators and gearboxes, and reinforcing towers are insufficient to accommodate the demands for bigger, taller and more powerful turbines. The DOE through the National Renewable Energy Laboratory (NREL) supports R&D efforts to develop lighter, more efficient and longer lasting wind turbines and advance turbine components. However, as wind turbine systems continue to increase in size and complexity, fundamental research and technology development has not kept pace with needs. New technologies to increase turbine life spans and to reduce costs are needed to realize wind electricity generation potentials. It is becoming quite evident that without a better understanding of static and dynamic response to normal and abnormal operating loads coupled with sophisticated flow analysis and control techniques, large turbine operating life and component life will be severely limited. Promising technologies include active load control and load alleviation systems to mitigate peak loads from damaging key components. This project addresses science and engineering challenges of developing enabling technologies for active load control for turbine applications using an innovative, translational microtab approach. Figure 1.1 illustrates the microtabs as applied on a wind turbine system. Extending wind turbine operating life is a crucial component for reducing the cost of wind-generated electricity, enabling wind

  6. 78 FR 16701 - Agency Information Collection Activities: Application for Foreign Trade Zone and/or Status... (United States)


    ... Foreign Trade Zone and/or Status Designation, and Application for Foreign Trade Zone Activity Permit... approval in accordance with the Paperwork Reduction Act: Application for Foreign Trade Zone Admission and/or Status Designation, and Application for Foreign Trade Zone Activity Permit (CBP Forms 214, 214A...

  7. Market penetration analysis for direct heat geothermal energy applications

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, R.J.; Nelson, R.A.


    This study is concerned with the estimation of the National geothermal market potential and penetration in direct heat applications for residences and certain industry segments. An important aspect of this study is that the analysis considers both known and anticipated goethermal resources. This allows for an estimation of the longer-range potential for geothermal applications. Thus the approach and results of this study provide new insights and valuable information not obtained from more limited, site-specific types of analyses. Estimates made in this study track geothermal market potential and projected penetration from the present to the year 2020. Private sector commercialization of geothermal energy over this period requires assistance in the identification of markets and market sizes, potential users, and appropriate technical applications.

  8. Cognitive approaches for patterns analysis and security applications (United States)

    Ogiela, Marek R.; Ogiela, Lidia


    In this paper will be presented new opportunities for developing innovative solutions for semantic pattern classification and visual cryptography, which will base on cognitive and bio-inspired approaches. Such techniques can be used for evaluation of the meaning of analyzed patterns or encrypted information, and allow to involve such meaning into the classification task or encryption process. It also allows using some crypto-biometric solutions to extend personalized cryptography methodologies based on visual pattern analysis. In particular application of cognitive information systems for semantic analysis of different patterns will be presented, and also a novel application of such systems for visual secret sharing will be described. Visual shares for divided information can be created based on threshold procedure, which may be dependent on personal abilities to recognize some image details visible on divided images.

  9. The technical analysis of the stock exchange and physics: Japanese candlesticks for solar activity (United States)

    Dineva, C.; Atanasov, V.


    In this article, we use the Japanese candlesticks, a method popular in the technical analysis of the Stock/Forex markets and apply it to a variable in physics-the solar activity. This method is invented and used exclusively for economic analysis and its application to a physical problem produced unexpected results. We found that the Japanese candlesticks are convenient tool in the analysis of the variables in the physics of the Sun. Based on our observations, we differentiated a new cycle in the solar activity.

  10. International Conference on Matrix Analysis and its Applications 2015

    CERN Document Server


    This volume presents recent advances in the field of matrix analysis based on contributions at the MAT-TRIAD 2015 conference. Topics covered include interval linear algebra and computational complexity, Birkhoff polynomial basis, tensors, graphs, linear pencils, K-theory and statistic inference, showing the ubiquity of matrices in different mathematical areas. With a particular focus on matrix and operator theory, statistical models and computation, the International Conference on Matrix Analysis and its Applications 2015, held in Coimbra, Portugal, was the sixth in a series of conferences. Applied and Computational Matrix Analysis will appeal to graduate students and researchers in theoretical and applied mathematics, physics and engineering who are seeking an overview of recent problems and methods in matrix analysis.

  11. Fungal aegerolysin-like proteins: distribution, activities, and applications. (United States)

    Novak, Maruša; Kraševec, Nada; Skočaj, Matej; Maček, Peter; Anderluh, Gregor; Sepčić, Kristina


    The aegerolysin protein family (from aegerolysin of the mushroom Agrocybe aegerita) comprises proteins of ∼15-20 kDa from various eukaryotic and bacterial taxa. Aegerolysins are inconsistently distributed among fungal species, and variable numbers of homologs have been reported for species within the same genus. As such noncore proteins, without a member of a protein family in each of the sequenced fungi, they can give insight into different species-specific processes. Some aegerolysins have been reported to be hemolytically active against mammalian erythrocytes. However, some function as bi-component proteins that have membrane activity in concert with another protein that contains a membrane attack complex/perforin domain. The function of most of aegerolysins is unknown, although some have been suggested to have a role in development of the organism. Potential biotechnological applications of aegerolysins are already evident, despite the limited scientific knowledge available at present. Some mushroom aegerolysins, for example, can be used as markers to detect and label specific membrane lipids. Others can be used as biomarkers of fungal exposure, where their genes can serve as targets for detection of fungi and their progression during infectious diseases. Antibodies against aegerolysins can also be raised as immuno-diagnostic tools. Aegerolysins have been shown to serve as a species determination tool for fungal phytopathogen isolates in terms of some closely related species, where commonly used internal transcribed spacer barcoding has failed. Moreover, strong promoters that regulate aegerolysin genes can promote secretion of heterologous proteins from fungi and have been successfully applied in simultaneous multi-gene expression techniques.

  12. [Application of magnetic materials in analysis on Chinese herb medicines]. (United States)

    Xu, Li-Wei; Wang, Jiu-Rong; Han, Xue-Feng


    China is the cradle of Chinese herb medicines,with rich plant resources. However, traditional processing methods have many disadvantages, such as high comsumption of organic solvent, long extraction time and high loss of effective constituents. For the purpose of rational use of Chinese herb medicines and accurate analysis on their constituents,the sample pre-treatment method with magnetic nanoparticles as the carrier brought new opportunities in recent years. after consulting literatures,the essay summarizes traditional extraction methods of Chinese herb medicines, characteristics of magnetic materials and their application in the analysis on Chinese herb medicines.

  13. Fringe pattern analysis for optical metrology theory, algorithms, and applications

    CERN Document Server

    Servin, Manuel; Padilla, Moises


    The main objective of this book is to present the basic theoretical principles and practical applications for the classical interferometric techniques and the most advanced methods in the field of modern fringe pattern analysis applied to optical metrology. A major novelty of this work is the presentation of a unified theoretical framework based on the Fourier description of phase shifting interferometry using the Frequency Transfer Function (FTF) along with the theory of Stochastic Process for the straightforward analysis and synthesis of phase shifting algorithms with desired properties such

  14. Application of Lie group analysis in geophysical fluid dynamics

    CERN Document Server

    Ibragimov, Ranis


    This is the first monograph dealing with the applications of the Lie group analysis to the modeling equations governing internal wave propagation in the deep ocean. A new approach to describe the nonlinear interactions of internal waves in the ocean is presented. While the central idea of the book is to investigate oceanic internal waves through the prism of Lie group analysis, it is also shown for the first time that internal wave beams, representing exact solutions to the equation of motion of stratified fluid, can be found by solving the given model as invariant solutions of nonlinear equat

  15. 76 FR 24570 - Proposed Information Collection (Application for VA Education Benefits) Activity; Comment Request (United States)


    ... AFFAIRS Proposed Information Collection (Application for VA Education Benefits) Activity; Comment Request.... Titles: a. Application for VA Education Benefits, VA Form 22-1990. b. Application for Transfer of Entitlement (TOE), Basic Educational Assistance Under the Montgomery GI Bill, VA Form 22-1990E. c. Application...

  16. 76 FR 40453 - Agency Information Collection (Application for VA Education Benefits) Activity Under OMB Review (United States)


    ... AFFAIRS Agency Information Collection (Application for VA Education Benefits) Activity Under OMB Review... INFORMATION: Titles: a. Application for VA Education Benefits, VA Form 22-1990. b. Application for Family Member to Use Transferred Benefits, VA Form 22-1990E. ] c. Application for VA Education Benefits Under...

  17. The Applications of Finite Element Analysis in Proximal Humeral Fractures (United States)

    Ye, Yongyu; You, Wei; Zhu, Weimin; Cui, Jiaming; Chen, Kang


    Proximal humeral fractures are common and most challenging, due to the complexity of the glenohumeral joint, especially in the geriatric population with impacted fractures, that the development of implants continues because currently the problems with their fixation are not solved. Pre-, intra-, and postoperative assessments are crucial in management of those patients. Finite element analysis, as one of the valuable tools, has been implemented as an effective and noninvasive method to analyze proximal humeral fractures, providing solid evidence for management of troublesome patients. However, no review article about the applications and effects of finite element analysis in assessing proximal humeral fractures has been reported yet. This review article summarized the applications, contribution, and clinical significance of finite element analysis in assessing proximal humeral fractures. Furthermore, the limitations of finite element analysis, the difficulties of more realistic simulation, and the validation and also the creation of validated FE models were discussed. We concluded that although some advancements in proximal humeral fractures researches have been made by using finite element analysis, utility of this powerful tool for routine clinical management and adequate simulation requires more state-of-the-art studies to provide evidence and bases. PMID:29081829

  18. The Applications of Finite Element Analysis in Proximal Humeral Fractures

    Directory of Open Access Journals (Sweden)

    Yongyu Ye


    Full Text Available Proximal humeral fractures are common and most challenging, due to the complexity of the glenohumeral joint, especially in the geriatric population with impacted fractures, that the development of implants continues because currently the problems with their fixation are not solved. Pre-, intra-, and postoperative assessments are crucial in management of those patients. Finite element analysis, as one of the valuable tools, has been implemented as an effective and noninvasive method to analyze proximal humeral fractures, providing solid evidence for management of troublesome patients. However, no review article about the applications and effects of finite element analysis in assessing proximal humeral fractures has been reported yet. This review article summarized the applications, contribution, and clinical significance of finite element analysis in assessing proximal humeral fractures. Furthermore, the limitations of finite element analysis, the difficulties of more realistic simulation, and the validation and also the creation of validated FE models were discussed. We concluded that although some advancements in proximal humeral fractures researches have been made by using finite element analysis, utility of this powerful tool for routine clinical management and adequate simulation requires more state-of-the-art studies to provide evidence and bases.

  19. A strategic analysis of Business Objects' portal application


    Kristinsson, Olafur Oskar


    Business Objects is the leading software firm producing business intelligence software. Business intelligence is a growing market. Small to medium businesses are increasingly looking at business intelligence. Business Objects' flagship product in the enterprise market is Business Objects XI and for medium-size companies it has Crystal Decisions. Portals are the front end for the two products. InfoView, Business Objects portal application, lacks a long-term strategy. This analysis evaluates...

  20. Performance, Applications, and Analysis of Rotating Detonation Engine Technologies (Preprint) (United States)


    Scott W. Theuerkauf, and Frederick R. Schauer Combustion Branch Turbine Engine Division Matthew L. Fotia, Andrew G. Naples, Christopher A...5c. PROGRAM ELEMENT NUMBER 62203F 6. AUTHOR(S) Brent A. Rankin, Scott W. Theuerkauf, and Frederick R. Schauer (AFRL/RQTC) Matthew L. Fotia, Andrew...unlimited. Performance, Application, and Analysis of Rotating Detonation Engine Technologies Brent A. Rankin1, Scott W. Theuerkauf2, and Frederick R

  1. Advanced approaches to failure mode and effect analysis (FMEA applications

    Directory of Open Access Journals (Sweden)

    D. Vykydal


    Full Text Available The present paper explores advanced approaches to the FMEA method (Failure Mode and Effect Analysis which take into account the costs associated with occurrence of failures during the manufacture of a product. Different approaches are demonstrated using an example FMEA application to production of drawn wire. Their purpose is to determine risk levels, while taking account of the above-mentioned costs. Finally, the resulting priority levels are compared for developing actions mitigating the risks.

  2. Multimedia Content Analysis and Indexing for Filtering and Retrieval Applications

    Directory of Open Access Journals (Sweden)

    N. Dimitrova


    Full Text Available Today’s multimedia landscape depends on advances in data compression technology coupled with high-bandwidth networks and storage capacity. Given its size and nature, how can multimedia content be analyzed and  indexed?  This paper surveys techniques for content-based analysis, retrieval and filtering of digital images, audio and video and focuses on basic methods for extracting features that will enable indexing and search applications. [ed.

  3. On One Application of Fourier Analysis in Plastic Surgery (United States)

    Rakhimov, Abdumalik; Zainuddin, Hishamuddin

    In present paper, we discuss the spectral methods of measurement of the degree of speech and/or quality of sound by comparing the coefficient of performance indicators depending on energy distributions, ratio of energy of the fundamental tone and energy of overtones. Such a method is very efficient for string oscillation with different initial conditions and it is useful for justification of applications of Fourier analysis in plastic surgery in treatment of some medical diseases.

  4. Lyapunov analysis: from dynamical systems theory to applications (United States)

    Cencini, Massimo; Ginelli, Francesco


    stable and unstable directions associated with Lyapunov exponents. Recently, novel and efficient algorithms for computing CLVs have become available, turning them into a practical tool for the study and characterization of chaotic dynamical systems, especially when many degrees of freedom are considered. Applications include—but are not limited to—the characterization of collective chaotic modes and the study of intermittency in shell models for turbulence. This section also includes a pedagogical discussion of CLVs in low dimensional Hamiltonian systems. Time series analysis. The computation of Lyapunov exponents from time series data is a very active field of research playing a crucial role in experimental studies, with applications ranging from nonlinear optics to neuroscience. The need to reconstruct a higher dimensional phase space from scalar or lower dimensional data poses fundamental issues, introducing spurious Lyapunov exponents and limiting the accuracy when quantities such as the Kaplan-Yorke-dimension or the Kolmogorov-Sinai entropy are concerned. Recent advances based on CLVs, however, may help in identifying such spurious exponents, increasing the accuracy of embedding techniques. Many-body systems. The study of many-body dynamical systems plays a fundamental role in the debate on the foundations of statistical physics. In this respect, the discovery of long wavelength tangent space modes associated with close-to-zero Lyapunov exponents, the so-called hydrodynamic Lyapunov modes, has raised hopes that a clear link could be established between hydrodynamic transport coefficients and microscopic dynamical properties. In this section, three contributions discuss Lyapunov analysis applied to many-body systems such as hard disks and lattices of interacting classical spins. Spatiotemporal chaos and hyperbolicity. Spatially extended chaotic systems pose a number of new issues when spatiotemporal chaos is considered, ranging from questions on its extensivity


    Directory of Open Access Journals (Sweden)

    S. Munapo


    Full Text Available

    ENGLISH ABSTRACT: This paper presents a new procedure for analysing and managing activity sequences in projects. The new procedure determines critical activities, critical path, start times, free floats, crash limits, and other useful information without the use of the network model. Even though network models have been successfully used in project management so far, there are weaknesses associated with the use. A network is not easy to generate, and dummies that are usually associated with it make the network diagram complex – and dummy activities have no meaning in the original project management problem. The network model for projects can be avoided while still obtaining all the useful information that is required for project management. What are required are the activities, their accurate durations, and their predecessors.

    AFRIKAANSE OPSOMMING: Die navorsing beskryf ’n nuwerwetse metode vir die ontleding en bestuur van die sekwensiële aktiwiteite van projekte. Die voorgestelde metode bepaal kritiese aktiwiteite, die kritieke pad, aanvangstye, speling, verhasing, en ander groothede sonder die gebruik van ’n netwerkmodel. Die metode funksioneer bevredigend in die praktyk, en omseil die administratiewe rompslomp van die tradisionele netwerkmodelle.

  6. Design professional activity analysis in design management

    Directory of Open Access Journals (Sweden)

    Claudia de Souza Libanio


    Full Text Available Design use perception, as an essential element for achieving competitive advantage, also suggests the need to manage the design activities in companies. However, a few is discussed about the activity of these design professionals who participate in this process, their roles, functions and competencies, including  their connections to a company and other involved sectors. This article aims to analyze, during the design management processes, the work relations of design professionals connected to organizations both internal and externally, in order to comprehend the structure and intervenient factors on the activity of these professionals, as well as the interactions with their main coworkers. The methodology was exploratory and qualitative, using in-depth interviews with three design professionals. Subsequently, the responses were analyzed allowing the comparison of these obtained data to the theoretical bases researched. Through this case study, it was possible to realize the aspects and the structure of the design professional activity, connected intern and externally to organizations, as well as its relations with the main coworkers.

  7. A Micro Fluorescent Activated Cell Sorter for Astrobiology Applications (United States)

    Platt, Donald W.; Hoover, Richard B.


    A micro-scale Fluorescent Activated Cell Sorter (microFACS) for astrobiology applications is under development. This device is designed to have a footprint of 7 cm x 7 cm x 4 cm and allow live-dead counts and sorting of cells that have fluorescent characteristics from staining. The FACS system takes advantage of microfluidics to create a cell sorter that can fit in the palm of the hand. A micron-scale channel allows cells to pass by a blue diode which causes emission of marker-expressed cells which are detected by a filtered photodetector. A small microcontroller then counts cells and operates high speed valves to select which chamber the cell is collected in (a collection chamber or a waste chamber). Cells with the expressed characteristic will be collected in the collection chamber. This system has been built and is currently being tested. We are also designing a system with integrated MEMS-based pumps and valves for a small and compact unit to fly on small satellite-based biology experiments.

  8. Application of time frequency and wavelet analysis to the diagnosis of epilepsy (United States)

    Sun, Mingui; Pon, Lin-Sen; Scheuer, Mark L.; Sclabassi, Robert J.


    Wavelet transforms and time-frequency distributions are powerful techniques for analysis of nonstationary biomedical signals. This paper investigates three applications of these techniques to multichannel electroencephalography (EEG) for the diagnosis of epilepsy. Wavelet transforms are utilized to detect the onset of seizures at different sites of subdural electrodes, and to extract spike patterns from EEG data recorded from the scalp. Time-frequency distributions are applied to characterize the early activity of seizures.

  9. Active Shape Analysis of Mandibular Growth

    DEFF Research Database (Denmark)

    Hilger, Klaus Baggesen; Larsen, Rasmus; Kreiborg, Sven


    This work contains a clinical validation using biological landmarks of a Geometry Constrained Diffusion registration of mandibular surfaces. Canonical Correlations Analysis is extended to analyse 3D landmarks and the correlations are used as similarity measures for landmark clustering. A novel Ac...

  10. Faculty Activity Analysis in the Universidad Tecnica Del Estado Campuses. (United States)

    Karadima, Oscar

    An analysis of academic activities of college faculty at the eight campuses of Chile's Universidad Tecnica del Estado was conducted. Activities were grouped into seven categories: direct teaching, indirect teaching, research, community services, faculty development, academic administration, and other activities. Following the narrative…

  11. A Cost Benefit Analysis of Radio Frequency Identification (RFID) Implementation at the Defense Microelectronics Activity (DMEA) (United States)


    are generally used in passive tag applications with high- water content, such as fruit. 7 Table 1. RFID Tag Attributes Active RFID Passive RFID ...Antennas As with all RFID technologies, antennas come in a large range of sizes, from under a square centimeter to larger than a square meter (Asif...ANALYSIS OF RADIO FREQUENCY IDENTIFICATION ( RFID ) IMPLEMENTATION AT THE DEFENSE MICROELECTRONICS ACTIVITY (DMEA) by James B. Gerber December

  12. Comparative Analysis of Conventional Method with Activity Based Costing in PT Mulia Sejati Gallery


    Erena, Irma Nadia; Gani, Engelwati


    The goal of this research was to provide readers the information about the calculation methods, both traditional and activity-based costing in the application of the cost of production. The method used in this research was the qualitative method. The analysis was done by calculating the amount of the production cost using the traditional system and the magnitude of the production cost when using the activity-based costing system. The amount of each acquisition was then performed into data ana...

  13. Regulatory activities of government: analysis of determinants

    Directory of Open Access Journals (Sweden)

    Primož Pevcin


    Full Text Available International comparisons show that large cross-country differences exist in the overall macro extent of regulation of the economy. In this context, the main purpose of the article is to investigate, why such differences exist by identifying and empirically verifying the effect of various factors that could potentially shape those differences. Empirical analysis based on the sample of 32 developed and democratic countries revealed that almost 70 % of variation in the macro extent of regulation could be explained with 7 statistically significant explanatory variables. The econometric analysis revealed that the macro extent of regulation decreases with income inequality in society, with the level of economic development, with the sizeof economy, with the share of transfer spending in GDP and with the share of government employment in labour force. On the other hand, the extent of regulation is positively related to government ownership of enterprises and to presidential political regime

  14. Characterization of population exposure to organochlorines: a cluster analysis application. (United States)

    Guimarães, Raphael Mendonça; Asmus, Carmen Ildes Rodrigues Fróes; Burdorf, Alex


    This study aimed to show the results from a cluster analysis application in the characterization of population exposure to organochlorines through variables related to time and exposure dose. Characteristics of 354 subjects in a population exposed to organochlorine pesticides residues related to time and exposure dose were subjected to cluster analysis to separate them into subgroups. We performed hierarchical cluster analysis. To evaluate the classification accuracy, compared to intra-group and inter-group variability by ANOVA for each dimension. The aggregation strategy was accomplished by the method of Ward. It was, for the creation of clusters, variables associated with exposure and routes of contamination. The information on the estimated intake doses of compound were used to weight the values of exposure time at each of the routes, so as to obtain values proxy exposure intensity. The results showed three clusters: cluster 1 (n = 45), characteristics of greatest exposure, the cluster 2 (n = 103), intermediate exposure, and cluster 3 (n = 206), less exposure. The bivariate analyzes performed with groups that are groups showed a statistically significant difference. This study demonstrated the applicability of cluster analysis to categorize populations exposed to organochlorines and also points to the relevance of typological studies that may contribute to a better classification of subjects exposed to chemical agents, which is typical of environmental epidemiology studies to a wider understanding of etiological, preventive and therapeutic contamination.

  15. Near-Real time analysis of seismic data of active volcanoes: Software implementations of time sequence data analysis

    Directory of Open Access Journals (Sweden)

    J. Vila


    Full Text Available This paper presents the development and applications of a software-based quality control system that monitors volcano activity in near-real time. On the premise that external seismic manifestations provide information directly related to the internal status of a volcano, here we analyzed variations in background seismic noise. By continuous analysis of variations in seismic waveforms, we detected clear indications of changes in the internal status. The application of this method to data recorded in Villarrica (Chile and Tungurahua (Ecuador volcanoes demonstrates that it is suitable to be used as a forecasting tool. A recent application of this developed software-based quality control to the real-time monitoring of Teide – Pico Viejo volcanic complex (Spain anticipated external episodes of volcanic activity, thus corroborating the advantages and capacity of the methodology when implemented as an automatic real-time procedure.

  16. Applicability of DNA analysis on adhesive tape in forensic casework. (United States)

    Zech, Wolf-Dieter; Malik, Naseem; Thali, Michael


    Adhesive tape is commonly used in crimes and is often the subject of forensic evaluation. DNA analysis of adhesive tape can provide DNA profiles of suspects. The object of this study was to evaluate the applicability of DNA analysis on adhesive tape samples in forensic casework. We retrospectively reviewed all cases involving adhesive tape or similar items received by our institute for DNA analysis during the past 11 years. From 100 forensic cases reviewed, 150 adhesive tape samples were examined. A total of 98 DNA profiles were obtained from these samples. Sixty-two of the profiles provided feasible case-relevant information. In conclusion, DNA profiling of adhesive tape samples can be useful in a variety of forensic cases. © 2012 American Academy of Forensic Sciences.

  17. Time series analysis methods and applications for flight data

    CERN Document Server

    Zhang, Jianye


    This book focuses on different facets of flight data analysis, including the basic goals, methods, and implementation techniques. As mass flight data possesses the typical characteristics of time series, the time series analysis methods and their application for flight data have been illustrated from several aspects, such as data filtering, data extension, feature optimization, similarity search, trend monitoring, fault diagnosis, and parameter prediction, etc. An intelligent information-processing platform for flight data has been established to assist in aircraft condition monitoring, training evaluation and scientific maintenance. The book will serve as a reference resource for people working in aviation management and maintenance, as well as researchers and engineers in the fields of data analysis and data mining.

  18. Analog and digital signal analysis from basics to applications

    CERN Document Server

    Cohen Tenoudji, Frédéric


    This book provides comprehensive, graduate-level treatment of analog and digital signal analysis suitable for course use and self-guided learning. This expert text guides the reader from the basics of signal theory through a range of application tools for use in acoustic analysis, geophysics, and data compression. Each concept is introduced and explained step by step, and the necessary mathematical formulae are integrated in an accessible and intuitive way. The first part of the book explores how analog systems and signals form the basics of signal analysis. This section covers Fourier series and integral transforms of analog signals, Laplace and Hilbert transforms, the main analog filter classes, and signal modulations. Part II covers digital signals, demonstrating their key advantages. It presents z and Fourier transforms, digital filtering, inverse filters, deconvolution, and parametric modeling for deterministic signals. Wavelet decomposition and reconstruction of non-stationary signals are also discussed...

  19. Neutron resonance analysis for nuclear safeguards and security applications

    Directory of Open Access Journals (Sweden)

    Paradela Carlos


    Full Text Available Neutron-induced reactions can be used to study the properties of nuclear materials of interest in the fields of nuclear safeguards and security. The elemental and isotopic composition of these materials can be determined by using the presence of resonance structures. This idea is the basis of two non-destructive analysis techniques which have been developed at the GELINA neutron time-of-flight facility at JRC-Geel: Neutron Resonance Capture Analysis (NRCA and Neutron Resonance Transmission Analysis (NRTA. A combination of NRTA and NRCA has been proposed for the characterisation of particle-like debris of melted fuel formed in severe nuclear accidents. In this work, we present a quantitative validation of the NRTA technique which was used to determine the areal densities of Pu enriched reference samples used for safeguards applications. Less than 2% bias has been obtained for the fissile isotopes, with well-known total cross sections.

  20. Application of data envelopment analysis models in supply chain management

    DEFF Research Database (Denmark)

    Soheilirad, Somayeh; Govindan, Kannan; Mardani, Abbas


    Supply chain management aims to designing, managing and coordinating material/product, information and financial flows to fulfill the customer requirements at low costs and thereby increasing supply chain profitability. In the last decades, data envelopment analysis has become the main topic...... of interest as a mathematical tool to evaluate supply chain management. While, various data envelopment analysis models have been suggested to measure and evaluate the supply chain management, there is a lack of research regarding to systematic literature review and classification of study in this field...... have been attained to reach a comprehensive review of data envelopment analysis models in evaluation supply chain management. Consequently, the selected published articles have been categorized by author name, the year of publication, technique, application area, country, scope, data envelopment...

  1. An investigation into the application of customer profitability analysis as a strategic decision-making tool in a hospitality environment


    Noone, Breffni M


    The primary objective of this study was to investigate the Applicability of Customer Profitability Analysis as a strategic decision-making technique in a hospitality environment. The study commenced with a review of literature in the fields of Yield Management, Customer Profitability Analysis (CPA) and Activity-Based Costing (ABC), with ABC being identified as an appropriate method of costing to use in CPA. Issues arising from the implementation of an Activity-Based CPA including the purpose ...

  2. Structure Modification toward Applicability Domain of a QSAR/QSPR Model Considering Activity/Property. (United States)

    Ochi, Shoki; Miyao, Tomoyuki; Funatsu, Kimito


    In drug and material design, the activity and property values of the designed chemical structures can be predicted by quantitative structure-activity and structure-property relationship (QSAR/QSPR) models. When a QSAR/QSPR model is applied to chemical structures, its applicability domain (AD) must be considered. The predicted activity/property values are only reliable for chemical structures inside the AD. Chemical structures outside the AD are usually neglected, as the predicted values are unreliable. The purpose of this study is to develop a methodology for obtaining novel chemical structures with the desired activity or property based on a QSAR/QSPR model by making use of the neglected structures. We propose a structure modification strategy for the AD that considers the activity and property simultaneously. The AD is defined by a one-class support vector machine and the structure modification is guided by a partial derivative of the AD model and matched molecular pairs analysis. Three proof-of-concept case studies generate novel chemical structures inside the AD that exhibit preferable activity/property values according to the QSAR/QSPR model. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Risk and safety analysis for Florida commercial aerial application operations (United States)

    Robbins, John Michael

    The purpose of this study was to determine self-reported perceptions in the areas of agroterrorism, bioterrorism, chemical exposure and Federal Aviation Administration (FAA) oversight. The aerial application industry has been in existence since the 1920's with a gamut of issues ranging from pesticide drift to counterterrorism. The attacks of September 11th, 2001, caused a paradigm shift in the way the United States views security and, more importantly, the prevention of malicious activity. Through the proper implementation and dissemination of educational materials dealing with industry specific concerns, it is imperative that everyone has the proper level of resources and training to effectively manage terrorist threats. This research study was designed to interpret how aerial applicators view these topics of concern and how they perceive the current threat level of terrorism in the industry. Research results were consistent, indicating that a high number of aerial applicators in the state of Florida are concerned with these topics. As a result, modifications need to be made with respect to certain variables. The aerial application industry works day in and day out to provide a professional service that helps maintain the integrity of the food and commodities that we need to survive. They are a small percentage of the aviation community that we all owe a great deal for the vital and necessary services they provide.

  4. Digital image processing and analysis for activated sludge wastewater treatment. (United States)

    Khan, Muhammad Burhan; Lee, Xue Yong; Nisar, Humaira; Ng, Choon Aun; Yeap, Kim Ho; Malik, Aamir Saeed


    Activated sludge system is generally used in wastewater treatment plants for processing domestic influent. Conventionally the activated sludge wastewater treatment is monitored by measuring physico-chemical parameters like total suspended solids (TSSol), sludge volume index (SVI) and chemical oxygen demand (COD) etc. For the measurement, tests are conducted in the laboratory, which take many hours to give the final measurement. Digital image processing and analysis offers a better alternative not only to monitor and characterize the current state of activated sludge but also to predict the future state. The characterization by image processing and analysis is done by correlating the time evolution of parameters extracted by image analysis of floc and filaments with the physico-chemical parameters. This chapter briefly reviews the activated sludge wastewater treatment; and, procedures of image acquisition, preprocessing, segmentation and analysis in the specific context of activated sludge wastewater treatment. In the latter part additional procedures like z-stacking, image stitching are introduced for wastewater image preprocessing, which are not previously used in the context of activated sludge. Different preprocessing and segmentation techniques are proposed, along with the survey of imaging procedures reported in the literature. Finally the image analysis based morphological parameters and correlation of the parameters with regard to monitoring and prediction of activated sludge are discussed. Hence it is observed that image analysis can play a very useful role in the monitoring of activated sludge wastewater treatment plants.

  5. Open-box spectral clustering: applications to medical image analysis. (United States)

    Schultz, Thomas; Kindlmann, Gordon L


    Spectral clustering is a powerful and versatile technique, whose broad range of applications includes 3D image analysis. However, its practical use often involves a tedious and time-consuming process of tuning parameters and making application-specific choices. In the absence of training data with labeled clusters, help from a human analyst is required to decide the number of clusters, to determine whether hierarchical clustering is needed, and to define the appropriate distance measures, parameters of the underlying graph, and type of graph Laplacian. We propose to simplify this process via an open-box approach, in which an interactive system visualizes the involved mathematical quantities, suggests parameter values, and provides immediate feedback to support the required decisions. Our framework focuses on applications in 3D image analysis, and links the abstract high-dimensional feature space used in spectral clustering to the three-dimensional data space. This provides a better understanding of the technique, and helps the analyst predict how well specific parameter settings will generalize to similar tasks. In addition, our system supports filtering outliers and labeling the final clusters in such a way that user actions can be recorded and transferred to different data in which the same structures are to be found. Our system supports a wide range of inputs, including triangular meshes, regular grids, and point clouds. We use our system to develop segmentation protocols in chest CT and brain MRI that are then successfully applied to other datasets in an automated manner.

  6. Applications of microcalorimetry in the antibacterial activity evaluation of various Rhizoma coptidis. (United States)

    Feng, Xue; Yan, Dan; Zhao, Kui-Jun; Luo, Jiao-Yang; Ren, Yong-Shen; Kong, Wei-Jun; Han, Yu-Mei; Xiao, Xiao-He


    Various Rhizoma coptidis are commonly used in clinical applications due to their strong antibacterial effect. The antibacterial effect of various R. coptidis were evaluated by microcalorimetry together with statistical analysis. The dried roots of Coptis chinensis Franch, Coptis deltoidea C.Y. Cheng et Hsiao, and Coptis teeta Wall (Ranunculaceae) were identified by Prof. Xiao-He Xiao. The herbs were tested using thermal activity monitor (TAM) air isothermal microcalorimeter, ampoule mode, to evaluate the biological activity. The dynamic energy metabolism information about the Staphylococcus aureus growth at 37°C was analyzed with principal component analysis. From the principle component analysis on quantitative parameters, the action of various R. coptidis on S. aureus growth at 37°C could be easily evaluated by analyzing the change of values of the two main parameters: the growth rate constant of first stage (k(1)) and the maximum heat rating of the first stage (P(1)). And the results of paired t-test show that there were no notable differences between inhibitory ratios calculated with k(1) and that of P(1). Using microdilution method, the minimal inhibitory concentrations (MIC) of C. chinensis, C. deltoidea, and C. teeta were detected, and they were 77.8 ± 2, 116.6 ± 4, 93.3 ± 2 μg/mL, respectively. This work provided a useful method for the evaluation of antibacterial activity of various R. coptidis.

  7. High-frequency underwater plasma discharge application in antibacterial activity (United States)

    Ahmed, M. W.; Choi, S.; Lyakhov, K.; Shaislamov, U.; Mongre, R. K.; Jeong, D. K.; Suresh, R.; Lee, H. J.


    Plasma discharge is a novel disinfection and effectual inactivation approach to treat microorganisms in aqueous systems. Inactivation of Gram-negative Escherichia coli ( E. coli) by generating high-frequency, high-voltage, oxygen (O2) injected and hydrogen peroxide (H2O2) added discharge in water was achieved. The effect of H2O2 dose and oxygen injection rate on electrical characteristics of discharge and E. coli disinfection has been reported. Microbial log reduction dependent on H2O2 addition with O2 injection was observed. The time variation of the inactivation efficiency quantified by the log reduction of the initial E. coli population on the basis of optical density measurement was reported. The analysis of emission spectrum recorded after discharge occurrence illustrated the formation of oxidant species (OH•, H, and O). Interestingly, the results demonstrated that O2 injected and H2O2 added, underwater plasma discharge had fabulous impact on the E. coli sterilization. The oxygen injection notably reduced the voltage needed for generating breakdown in flowing water and escalated the power of discharge pulses. No impact of hydrogen peroxide addition on breakdown voltage was observed. A significant role of oxidant species in bacterial inactivation also has been identified. Furthermore the E. coli survivability in plasma treated water with oxygen injection and hydrogen peroxide addition drastically reduced to zero. The time course study also showed that the retardant effect on E. coli colony multiplication in plasma treated water was favorable, observed after long time. High-frequency underwater plasma discharge based biological applications is technically relevant and would act as baseline data for the development of novel antibacterial processing strategies.

  8. High-frequency underwater plasma discharge application in antibacterial activity

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, M. W.; Choi, S.; Lyakhov, K.; Shaislamov, U. [Jeju National University, Department of Nuclear and Energy Engineering (Korea, Republic of); Mongre, R. K.; Jeong, D. K. [Jeju National University, Faculty of Biotechnology (Korea, Republic of); Suresh, R.; Lee, H. J., E-mail: [Jeju National University, Department of Nuclear and Energy Engineering (Korea, Republic of)


    Plasma discharge is a novel disinfection and effectual inactivation approach to treat microorganisms in aqueous systems. Inactivation of Gram-negative Escherichia coli (E. coli) by generating high-frequency, high-voltage, oxygen (O{sub 2}) injected and hydrogen peroxide (H{sub 2}O{sub 2}) added discharge in water was achieved. The effect of H{sub 2}O{sub 2} dose and oxygen injection rate on electrical characteristics of discharge and E. coli disinfection has been reported. Microbial log reduction dependent on H{sub 2}O{sub 2} addition with O{sub 2} injection was observed. The time variation of the inactivation efficiency quantified by the log reduction of the initial E. coli population on the basis of optical density measurement was reported. The analysis of emission spectrum recorded after discharge occurrence illustrated the formation of oxidant species (OH{sup •}, H, and O). Interestingly, the results demonstrated that O{sub 2} injected and H{sub 2}O{sub 2} added, underwater plasma discharge had fabulous impact on the E. coli sterilization. The oxygen injection notably reduced the voltage needed for generating breakdown in flowing water and escalated the power of discharge pulses. No impact of hydrogen peroxide addition on breakdown voltage was observed. A significant role of oxidant species in bacterial inactivation also has been identified. Furthermore the E. coli survivability in plasma treated water with oxygen injection and hydrogen peroxide addition drastically reduced to zero. The time course study also showed that the retardant effect on E. coli colony multiplication in plasma treated water was favorable, observed after long time. High-frequency underwater plasma discharge based biological applications is technically relevant and would act as baseline data for the development of novel antibacterial processing strategies.

  9. Redox-Active Metal-Organic Composites for Highly Selective Oxygen Separation Applications

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Wen [Physical & Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA; Banerjee, Debasis [Physical & Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA; Liu, Jian [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Schaef, Herbert T. [Physical & Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA; Crum, Jarrod V. [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Fernandez, Carlos A. [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Kukkadapu, Ravi K. [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA 99354 USA; Nie, Zimin [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Nune, Satish K. [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Motkuri, Radha K. [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Chapman, Karena W. [X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne IL 60439 USA; Engelhard, Mark H. [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA 99354 USA; Hayes, James C. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA; Silvers, Kurt L. [National Security Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA; Krishna, Rajamani [Van' t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904 1098 XH Amsterdam The Netherlands; McGrail, B. Peter [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Liu, Jun [Energy and Environment Directorate, Pacific Northwest National Laboratory, Richland WA 99354 USA; Thallapally, Praveen K. [Physical & Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland WA 99352 USA


    Incorporating, a redox active organometallic molIncorporating, a redox active organometallic molecule within a porous matrix is a useful strategy to form redox active composite materials for emerging applications such as energy storage, electro-catalysis and electro-magnetic separation. Herein we report a new class of stable, redox active metal organic composites for oxygen/air separation with exceptional efficiency. In particular, Ferrocene impregnated in a thermally stable hierarchical porous framework showed a saturation uptake capacity of >51 mg/g for oxygen at a very low relative saturation pressure (P/Po) of 0.06. The material shows excellent O2 selectivity from air as evident from experimental and simulated breakthrough experiments. In detail structural analysis using 57Fe-Mössbauer, X-ray photoelectron spectroscopy (XPS) and pair distribution function (PDF) analysis show that of O2 adsorption affinity and selectivity originates by the formation Fe3+-O oxide due to the highly reactive nature of the organometallics imbedded in the porous matrix.

  10. The peripheral dopaminergic system: morphological analysis, functional and clinical applications. (United States)

    Amenta, F; Ricci, A; Tayebati, S K; Zaccheo, D


    . Dopamine acting as autocrine or paracrine substance is probably involved in the regulation of immune activity. Human peripheral blood lymphocytes contain dopamine and express plasma membrane and vesicular dopamine transporters as well as dopamine D3, D4 and D5 receptors. Another recently characterized peripheral dopaminergic system is located in the lung. Dopamine D1-like receptor immunoreactive structures were found in a small percentage of nerve fibres contained in pulmonary nerve trunks. D1-immunoreactive nerve fibres were approximately 2-3% of total fibres, whereas D5-immunoreactive fibres accounted approximately for 5-6% of total fibres. Also dopamine D2-like receptor immunoreactive fibres were found in pulmonary trunks. D2-immunoreactive fibres accounted for approximately 3-5% of total nerve fibres, D3 receptor-immnunoreactive fibres accounted for about 8-10% of total nerve fibres, whereas only rare profiles of D4 receptor protein-immunoreactive fibres were observed. Dopamine recepetor protein immunostaining was also found in neurons of nodose ganglion, that display immunoreactivity for different neuropeptides. Based on the correspondence between the number of dopamine receptor immunoreactive pulmonary nerve fibres and of vagal ganglionic neurons immunoreactive for dopamine receptors it is possible to hypothesize that these receptors are located on pulmonary afferents. In spite of the heterogeneity of peripheral systems expressing dopamine receptors, analysis of their localization with appropriate microanatomical techniques may contribute to investigate their role in health and disease.

  11. Application of Open Source Technologies for Oceanographic Data Analysis (United States)

    Huang, T.; Gangl, M.; Quach, N. T.; Wilson, B. D.; Chang, G.; Armstrong, E. M.; Chin, T. M.; Greguska, F.


    NEXUS is a data-intensive analysis solution developed with a new approach for handling science data that enables large-scale data analysis by leveraging open source technologies such as Apache Cassandra, Apache Spark, Apache Solr, and Webification. NEXUS has been selected to provide on-the-fly time-series and histogram generation for the Soil Moisture Active Passive (SMAP) mission for Level 2 and Level 3 Active, Passive, and Active Passive products. It also provides an on-the-fly data subsetting capability. NEXUS is designed to scale horizontally, enabling it to handle massive amounts of data in parallel. It takes a new approach on managing time and geo-referenced array data by dividing data artifacts into chunks and stores them in an industry-standard, horizontally scaled NoSQL database. This approach enables the development of scalable data analysis services that can infuse and leverage the elastic computing infrastructure of the Cloud. It is equipped with a high-performance geospatial and indexed data search solution, coupled with a high-performance data Webification solution free from file I/O bottlenecks, as well as a high-performance, in-memory data analysis engine. In this talk, we will focus on the recently funded AIST 2014 project by using NEXUS as the core for oceanographic anomaly detection service and web portal. We call it, OceanXtremes

  12. Mathematical analysis of complex cellular activity

    CERN Document Server

    Bertram, Richard; Teka, Wondimu; Vo, Theodore; Wechselberger, Martin; Kirk, Vivien; Sneyd, James


    This book contains two review articles on mathematical physiology that deal with closely related topics but were written and can be read independently. The first article reviews the basic theory of calcium oscillations (common to almost all cell types), including spatio-temporal behaviors such as waves. The second article uses, and expands on, much of this basic theory to show how the interaction of cytosolic calcium oscillators with membrane ion channels can result in highly complex patterns of electrical spiking. Through these examples one can see clearly how multiple oscillatory processes interact within a cell, and how mathematical methods can be used to understand such interactions better. The two reviews provide excellent examples of how mathematics and physiology can learn from each other, and work jointly towards a better understanding of complex cellular processes. Review 1: Richard Bertram, Joel Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger: Geometric Singular Perturbation Analysis of Burst...

  13. Pulsed flows in flow analysis: Potentialities, limitations and applications. (United States)

    González, Pablo; Knochen, Moisés; Sasaki, Milton K; Zagatto, Elias A G


    In flow analysis, use of a steady and pulseless flow was considered essential for ensuring a reproducible handling of the flowing sample. To this end, peristaltic and syringe pumps have been the propelling device in the vast majority of the flow analysers. Recently, the number of applications involving pulsed flow has been increasing. Most of them refer to use of solenoid pumps, the essence of the so-called multi-pumping flow systems. This review critically discusses the characteristics, potentialities and limitations of the pulsed flow systems, emphasizing the main advantageous characteristics of the streams involved, such as high radial mass transference and good mixing of the fluids. Diverse contributions ranging from instrumentation development to analytical applications are presented. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Nanosilicon properties, synthesis, applications, methods of analysis and control

    CERN Document Server

    Ischenko, Anatoly A; Aslalnov, Leonid A


    Nanosilicon: Properties, Synthesis, Applications, Methods of Analysis and Control examines the latest developments on the physics and chemistry of nanosilicon. The book focuses on methods for producing nanosilicon, its electronic and optical properties, research methods to characterize its spectral and structural properties, and its possible applications. The first part of the book covers the basic properties of semiconductors, including causes of the size dependence of the properties, structural and electronic properties, and physical characteristics of the various forms of silicon. It presents theoretical and experimental research results as well as examples of porous silicon and quantum dots. The second part discusses the synthesis of nanosilicon, modification of the surface of nanoparticles, and properties of the resulting particles. The authors give special attention to the photoluminescence of silicon nanoparticles. The third part describes methods used for studying and controlling the structure and pro...

  15. Wireless sensor networks concepts, applications, experimentation and analysis

    CERN Document Server

    Fahmy, Hossam Mahmoud Ahmad


    This book focuses on the principles of wireless sensor networks (WSNs), their applications, and their analysis tools, with meticulous attention paid to definitions and terminology. This book presents the adopted technologies and their manufacturers in detail, making WSNs tangible for the reader. In introductory computer networking books, chapter sequencing follows the bottom-up or top-down architecture of the 7-layer protocol. This book addresses subsequent steps in this process, both horizontally and vertically, thus fostering a clearer and deeper understanding through chapters that elaborate on WSN concepts and issues. With such depth, this book is intended for a wide audience; it is meant to be a helper and motivator for senior undergraduates, postgraduates, researchers, and practitioners. It lays out important concepts and WSN-relate applications; uses appropriate literature to back research and practical issues; and focuses on new trends. Senior undergraduate students can use it to familiarize themselves...

  16. Monitoring of bolted joints using piezoelectric active-sensing for aerospace applications

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gyuhae [Los Alamos National Laboratory; Farrar, Charles R [Los Alamos National Laboratory; Park, Chan - Yik [ADD; Jun, Seung - Moon [ADD


    This paper is a report of an initial investigation into tracking and monitoring the integrity of bolted joints using piezoelectric active-sensors. The target application of this study is a fitting lug assembly of unmanned aerial vehicles (UAVs), where a composite wing is mounted to a UAV fuselage. The SHM methods deployed in this study are impedance-based SHM techniques, time-series analysis, and high-frequency response functions measured by piezoelectric active-sensors. Different types of simulated damage are introduced into the structure, and the capability of each technique is examined and compared. Additional considerations encountered in this initial investigation are made to guide further thorough research required for the successful field deployment of this technology.

  17. Processing and characterization of activated carbon coated magnetic particles for biomedical applications

    Energy Technology Data Exchange (ETDEWEB)

    Ramanujan, R.V. [School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798 (Singapore)]. E-mail:; Purushotham, S. [School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798 (Singapore); Chia, M.H. [School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798 (Singapore)


    Synthesis and characterization of Magnetically Targeted Carrier (MTC) powders consisting of activated carbon coated iron particles were carried out. Powders with activated carbon content of 5% by weight (Fe5C) and 35% by weight (Fe35C) were studied. Powders were synthesized via the high energy ball milling route, and the influence of milling time on the morphology, magnetic properties and drug adsorption and desorption characteristics was investigated. Physical and structural characterization included electron microscopy, size analysis, and X-ray diffraction. The magnetic properties, and theophylline adsorption and desorption characteristics were studied. Fe35C milled for 10 h was found to be a suitable candidate for MTC applications with fine size, stable magnetic properties, and superior drug adsorption and desorption behavior.

  18. Application of risk analysis in water resourses management (United States)

    Varouchakis, Emmanouil; Palogos, Ioannis


    A common cost-benefit analysis approach, which is novel in the risk analysis of hydrologic/hydraulic applications, and a Bayesian decision analysis are applied to aid the decision making on whether or not to construct a water reservoir for irrigation purposes. The alternative option examined is a scaled parabolic fine variation in terms of over-pumping violations in contrast to common practices that usually consider short-term fines. Such an application, and in such detail, represents new feedback. The results indicate that the probability uncertainty is the driving issue that determines the optimal decision with each methodology, and depending on the unknown probability handling, each methodology may lead to a different optimal decision. Thus, the proposed tool can help decision makers (stakeholders) to examine and compare different scenarios using two different approaches before making a decision considering the cost of a hydrologic/hydraulic project and the varied economic charges that water table limit violations can cause inside an audit interval. In contrast to practices that assess the effect of each proposed action separately considering only current knowledge of the examined issue, this tool aids decision making by considering prior information and the sampling distribution of future successful audits. This tool is developed in a web service for the easier stakeholders' access.

  19. Determination of the archaeological origin of ceramic fragments characterized by neutron activation analysis, by means of the application of multivariable statistical analysis techniques;Determinacion del origen de fragmentos de ceramica arqueologica caracterizados con analisis por activacion neutronica, mediante la aplicacion de tecnicas de analisis estadistico multivariable

    Energy Technology Data Exchange (ETDEWEB)

    Almazan T, M. G.; Jimenez R, M.; Monroy G, F.; Tenorio, D. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Rodriguez G, N. L. [Instituto Mexiquense de Cultura, Subdireccion de Restauracion y Conservacion, Hidalgo poniente No. 1013, 50080 Toluca, Estado de Mexico (Mexico)


    The elementary composition of archaeological ceramic fragments obtained during the explorations in San Miguel Ixtapan, Mexico State, was determined by the neutron activation analysis technique. The samples irradiation was realized in the research reactor TRIGA Mark III with a neutrons flow of 1centre dot10{sup 13}ncentre dotcm{sup -2}centre dots{sup -1}. The irradiation time was of 2 hours. Previous to the acquisition of the gamma rays spectrum the samples were allowed to decay from 12 to 14 days. The analyzed elements were: Nd, Ce, Lu, Eu, Yb, Pa(Th), Tb, La, Cr, Hf, Sc, Co, Fe, Cs, Rb. The statistical treatment of the data, consistent in the group analysis and the main components analysis allowed to identify three different origins of the archaeological ceramic, designated as: local, foreign and regional. (Author)


    Directory of Open Access Journals (Sweden)

    Sukhodub L.B.


    Full Text Available In the last decades, serious attention is attracted by the use of natural antimicrobial drugs instead of the usual ones because of pathogens resistance to antibiotics. Chitosan (CS is widely used as an antimicrobial agent owing to its high biodegradability, nontoxicity and antimicrobial properties. CS is a cationic polysaccharide obtained by partial deacetylation of chitin, the major component of crustacean shells. In last time cultivation of fungi provides an alternative source of the CS obtaining: Chitin makes up 45 % of the A. niger and M. rouxii cell wall content and up to 20 % of the P. notatum cell wall content In contrast to other polymers, chitosan is a hydrophilic polymer with positive charge and has three types of functional groups: amino group at position C-2 in each deacetylated structural unit, as well as primary and secondary hydroxyl groups at C-6 and C-3 positions respectively. This causes its ability to form new hydrofilic medicals on the basis of known drugs, as well as the formation of drug release systems. CS is unique adsorbent and it is possible to combine it with another drugs. The natural ability of CS for gelation is used in the preparation of the hemostatic agent "Celox", that is effective for preventing fatalities when arterial bleeding occurs on the battlefield. The clotting of "Celox" occurs much faster than other hemostatic agents. Antimicrobial activity of chitosan against many Gram-positive and Gram-negative bacteria, filamentous fungi and yeasts has been widely demonstrated in the scientific literature.There are some reported mechanisms for antibacterial activity: positively charged due to NH3+ groups Chitosan interact with negatively charged functional groups at the cell surface and compromise the cell wall or outer membrane. In the case of Gram-positive bacteria, lipoteichoic acid could provide a molecular linkage for chitosan at the cell surface, allowing it to disturb membrane functions. Lipopolysaccharides

  1. Forecasting of innovative activity on the basis of application of technology of Foresight

    Directory of Open Access Journals (Sweden)

    Nazarova Natalia Leonidovna


    Full Text Available In article the basic questions of forecasting of innovative activity of economic systems are considered. Forsyte's bases are considered. Necessity, importance, success of application of technology of Forsyte for forecasting of innovative activity are proved.

  2. HPLC–MS and HPLC–MS/MS analysis of seven active constituents of Xiao-Xu-Ming decoction and application to a pharmacokinetic study after oral administration to rat

    Directory of Open Access Journals (Sweden)

    Yilin Wang


    Full Text Available Xiao-xu-ming decoction (XXMD is a traditional Chinese medicine that has been widely used to treat theoplegia and its sequelae. This paper reports the development of three separate assays based on reversed phase high-performance liquid chromatography–mass spectrometry (HPLC–MS and HPLC–MS/MS for the determination of seven active constituents of XXMD viz oroxylin A-7-O-glucuronide, wogonoside, liquiritigenin, cimifugin, 5-O-methylvisammiol, glycyrrhizic acid and glycyrrhetinic acid in rat plasma. All calibration curves were linear (r >0.99 with lower limits of quantitation (LLOQs<12.4 ng/mL. Intra- and inter-day precisions (as relative standard deviation were all <10.7% with recoveries in the range of 88.7–113%. In addition, the seven analytes were shown to be stable in rat plasma samples under relevant storage conditions. The validated methods were successfully applied to a pharmacokinetic study in rat after oral administration of XXMD.


    Directory of Open Access Journals (Sweden)

    Agnieszka Kisło


    Full Text Available The beginning of the period where the impact of human activity took dangerous size is considered to be 40 years of the nineteenth century. Then the large-scale production of electricity increased production of metallurgical industry and transport development. Significant changes contributed to rapid population growth and urbanization and industrialization processes. Man by intensive exploitation reduces or completely exhausted most natural resources. This has resulted in the availability criterion, which is distinguished by inexhaustible and exhaustible resources. Exhaustible resources may include solar, wind, energy, ocean currents and the energy of the Earth. Exhaustible resources, however, are the elements of nature that as a result of the operation can be completely depleted or destroyed. These resources include: water, soil, plant world, animal world natural resources. The greater the intensity of acquiring human resources, the faster will be the depleted. There is also a very important division of exhaustible resources: non-renewable resources, renewable and very difficult reproducible (living areas. Non-renewable resources are mainly minerals, such as iron ore, crude oil, coal, sulfur, natural gas, useful stones, limestone, salt, and many other minerals. After extraction resources are processed, and the bed from which they were extracted can no longer be used. It is different from renewable resources; they are characterized by the fact that over time they are reconstituted, although, for this to happen balance of the environment through the rational use must be maintained. These resources include, among others, soil, water, flora and fauna, as well as atmospheric air.

  4. Application of forensic image analysis in accident investigations. (United States)

    Verolme, Ellen; Mieremet, Arjan


    Forensic investigations are primarily meant to obtain objective answers that can be used for criminal prosecution. Accident analyses are usually performed to learn from incidents and to prevent similar events from occurring in the future. Although the primary goal may be different, the steps in which information is gathered, interpreted and weighed are similar in both types of investigations, implying that forensic techniques can be of use in accident investigations as well. The use in accident investigations usually means that more information can be obtained from the available information than when used in criminal investigations, since the latter require a higher evidence level. In this paper, we demonstrate the applicability of forensic techniques for accident investigations by presenting a number of cases from one specific field of expertise: image analysis. With the rapid spread of digital devices and new media, a wealth of image material and other digital information has become available for accident investigators. We show that much information can be distilled from footage by using forensic image analysis techniques. These applications show that image analysis provides information that is crucial for obtaining the sequence of events and the two- and three-dimensional geometry of an accident. Since accident investigation focuses primarily on learning from accidents and prevention of future accidents, and less on the blame that is crucial for criminal investigations, the field of application of these forensic tools may be broader than would be the case in purely legal sense. This is an important notion for future accident investigations. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Linearly Polarized IR Spectroscopy Theory and Applications for Structural Analysis

    CERN Document Server

    Kolev, Tsonko


    A technique that is useful in the study of pharmaceutical products and biological molecules, polarization IR spectroscopy has undergone continuous development since it first emerged almost 100 years ago. Capturing the state of the science as it exists today, "Linearly Polarized IR Spectroscopy: Theory and Applications for Structural Analysis" demonstrates how the technique can be properly utilized to obtain important information about the structure and spectral properties of oriented compounds. The book starts with the theoretical basis of linear-dichroic infrared (IR-LD) spectroscop

  6. Applications of digital image analysis capability in Idaho (United States)

    Johnson, K. A.


    The use of digital image analysis of LANDSAT imagery in water resource assessment is discussed. The data processing systems employed are described. The determination of urban land use conversion of agricultural land in two southwestern Idaho counties involving estimation and mapping of crop types and of irrigated land is described. The system was also applied to an inventory of irrigated cropland in the Snake River basin and establishment of a digital irrigation water source/service area data base for the basin. Application of the system to a determination of irrigation development in the Big Lost River basin as part of a hydrologic survey of the basin is also described.

  7. PowerFactory applications for power system analysis

    CERN Document Server

    Gonzalez-Longatt, Francisco


    This book presents a comprehensive set of guidelines and applications of DIgSILENT PowerFactory, an advanced power system simulation software package, for different types of power systems studies. Written by specialists in the field, it combines expertise and years of experience in the use of DIgSILENT PowerFactory with a deep understanding of power systems analysis. These complementary approaches therefore provide a fresh perspective on how to model, simulate and analyse power systems. It presents methodological approaches for modelling of system components, including both classical and non-

  8. Stochastic analysis for gaussian random processes and fields with applications

    CERN Document Server

    Mandrekar, Vidyadhar S


    Stochastic Analysis for Gaussian Random Processes and Fields: With Applications presents Hilbert space methods to study deep analytic properties connecting probabilistic notions. In particular, it studies Gaussian random fields using reproducing kernel Hilbert spaces (RKHSs).The book begins with preliminary results on covariance and associated RKHS before introducing the Gaussian process and Gaussian random fields. The authors use chaos expansion to define the Skorokhod integral, which generalizes the Itô integral. They show how the Skorokhod integral is a dual operator of Skorokhod differenti

  9. PCA oversedation: application of Healthcare Failure Mode Effect (HFMEA) Analysis. (United States)

    Cronrath, Pam; Lynch, Timothy W; Gilson, Linda J; Nishida, Carol; Sembar, M Colleen; Spencer, Patricia J; West, Daidre Foote


    Hospital systems utilize many varied problem-solving processes to address system improvements and ensure patient safety. The Healthcare Failure Mode Effect Analysis (HFMEA) model is one of these tools and uses a multidisciplinary team to look at processes, diagramming the steps involved to identify potential failure points. The application of the HFMEA model allowed one large health care system to address a complex process by prioritizing proactive change improvements in order to prevent postoperative patient-controlled anesthesia oversedation events. The changes implemented identified 16 failure points with a hazard score of 16 or greater. One year later, the established system HFMEA goal was met: oversedation events were reduced by 50%.

  10. Statistical Analysis of Designed Experiments Theory and Applications

    CERN Document Server

    Tamhane, Ajit C


    A indispensable guide to understanding and designing modern experiments The tools and techniques of Design of Experiments (DOE) allow researchers to successfully collect, analyze, and interpret data across a wide array of disciplines. Statistical Analysis of Designed Experiments provides a modern and balanced treatment of DOE methodology with thorough coverage of the underlying theory and standard designs of experiments, guiding the reader through applications to research in various fields such as engineering, medicine, business, and the social sciences. The book supplies a foundation for the

  11. Application of the IPEBS method to dynamic contingency analysis

    Energy Technology Data Exchange (ETDEWEB)

    Martins, A.C.B. [FURNAS, Rio de Janeiro, RJ (Brazil); Pedroso, A.S. [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil)


    Dynamic contingency analysis is certainly a demanding task in the context of dynamic performance evaluation. This paper presents the results of a test for checking the contingency screening capability of the IPEBS method. A brazilian 1100-bus, 112-gen system was used in the test; the ranking of the contingencies based on critical clearing times obtained with IPEBS, was compared with the ranking derived from detailed time-domain simulation. The results of this comparison encourages us to recommended the use of the method in industry applications, in a complementary basis to the current method of time domain simulation. (author) 5 refs., 1 fig., 2 tabs.

  12. Applications of finite-element scaling analysis in primatology. (United States)

    Richtsmeier, J T


    The study of biological shape in three dimensions using landmark data can now be accomplished using several alternative methods. This report focuses on the use of finite-element scaling analysis in primate craniofacial morphology. The method is particularly useful in its ability to localize the differences between forms, thereby indicating those loci that differ most between specimens. Several examples of this feature are provided from primatological research. Particulars of the methods are also discussed in an attempt to provide the reader with cautionary knowledge for prudent application of the method in future research.

  13. The analysis of web application quality for electronic banking


    Jankovič, Jernej


    The purpose of this thesis is to demonstrate a systematic analysis of web applications quality for electronic banking. In the theoretical part we focused on the ISO/IEC 25000 standard, which deals with quality of the product. With help of SQuaRE set of standards we have reviewed the contents of some standards from ISO/IEC 25000 family. At the and we used ISO/IEC 25010 quality model and ISO/IEC 25040 which contains procedure for assessing the product quality. For the assessment of user in...

  14. Antibacterial activity and phytochemical analysis of leaf extracts of ...

    African Journals Online (AJOL)

    The phytochemical analysis of both the aqueous and methanolic extracts of edible indigenous medicinal plant Lasienthera africanum (“Editan”) and their antibacterial activities against clinical isolates, Escherichia coli, Salmonella typhi, Klebsiella pneumoniae and Staphylococcus aureus were investigated.

  15. Dual-Polarized Planar Phased Array Analysis for Meteorological Applications

    Directory of Open Access Journals (Sweden)

    Chen Pang


    Full Text Available This paper presents a theoretical analysis for the accuracy requirements of the planar polarimetric phased array radar (PPPAR in meteorological applications. Among many factors that contribute to the polarimetric biases, four factors are considered and analyzed in this study, namely, the polarization distortion due to the intrinsic limitation of a dual-polarized antenna element, the antenna pattern measurement error, the entire array patterns, and the imperfect horizontal and vertical channels. Two operation modes, the alternately transmitting and simultaneously receiving (ATSR mode and the simultaneously transmitting and simultaneously receiving (STSR mode, are discussed. For each mode, the polarimetric biases are formulated. As the STSR mode with orthogonal waveforms is similar to the ATSR mode, the analysis is mainly focused on the ATSR mode and the impacts of the bias sources on the measurement of polarimetric variables are investigated through Monte Carlo simulations. Some insights of the accuracy requirements are obtained and summarized.

  16. Applications of surface analysis and surface theory in tribology (United States)

    Ferrante, John


    Tribology, the study of adhesion, friction and wear of materials, is a complex field which requires a knowledge of solid state physics, surface physics, chemistry, material science, and mechanical engineering. It has been dominated, however, by the more practical need to make equipment work. With the advent of surface analysis and advances in surface and solid-state theory, a new dimension has been added to the analysis of interactions at tribological interfaces. In this paper the applications of tribological studies and their limitations are presented. Examples from research at the NASA Lewis Research Center are given. Emphasis is on fundamental studies involving the effects of monolayer coverage and thick films on friction and wear. A summary of the current status of theoretical calculations of defect energetics is presented. In addition, some new theoretical techniques which enable simplified quantitative calculations of adhesion, fracture, and friction are discussed.

  17. Youth physical activity self-efficacy: a concept analysis. (United States)

    Voskuil, Vicki R; Robbins, Lorraine B


    To report an analysis of the concept of youth physical activity self-efficacy. Physical activity self-efficacy is a concept that has been frequently examined as a key variable in research aimed at increasing physical activity among youth. Different conceptual definitions and empirical measures indicate the need for concept analysis to advance knowledge of the concept. Rodger's evolutionary method of concept analysis was used to collect and analyse the data. Social cognitive theory guided the analysis. The PubMed, Cumulative Index of Nursing and Allied Health Literature, PsychInfo, Educational Resources Information Center and Sociological Abstracts databases were searched for publications from 1990-2013. Search terms included self-efficacy, physical activity, youth, children, adolescent and teen. A total of 276 articles were identified. Fifty-five articles meeting inclusion criteria were included in the review. Data were analysed with particular focus on the attributes, antecedents and consequences of the concept. Defining attributes of physical activity self-efficacy were identified as personal cognition/perception, self-appraisal process, related action, power to choose physical activity, dynamic state and bi-dimensional nature. Antecedents and consequences were consistent with social cognitive theory. Youth physical activity self-efficacy is defined as a youth's belief in his/her capability to participate in physical activity and to choose physical activity despite existing barriers. This concept analysis provided an in-depth analysis and clarification of youth physical activity self-efficacy. Future research should be aimed at establishing consistency in conceptual definitions and empirical measurement to further develop the concept across disciplines. © 2015 John Wiley & Sons Ltd.

  18. Antibacterial activities of bacteriocins: application in foods and pharmaceuticals

    National Research Council Canada - National Science Library

    Yang, Shih-Chun; Lin, Chih-Hung; Sung, Calvin T; Fang, Jia-You


    .... Many recent studies have purified and identified bacteriocins for application in food technology, which aims to extend food preservation time, treat pathogen disease and cancer therapy, and maintain human health...

  19. Electro-Active Polymer (EAP) Actuators for Planetary Applications (United States)

    Bar-Cohen, Y.; Leary, S.; Shahinpoor, M.; Harrison, J. O.; Smith, J.


    NASA is seeking to reduce the mass, size, consumed power, and cost of the instrumentation used in its future missions. An important element of many instruments and devices is the actuation mechanism and electroactive polymers (EAP) are offering an effective alternative to current actuators. In this study, two families of EAP materials were investigated, including bending ionomers and longitudinal electrostatically driven elastomers. These materials were demonstrated to effectively actuate manipulation devices and their performance is being enhanced in this on-going study. The recent observations are reported in this paper, include the operation of the bending-EAP at conditions that exceed the harsh environment on Mars, and identify the obstacles that its properties and characteristics are posing to using them as actuators. Analysis of the electrical characteristics of the ionomer EAP showed that it is a current driven material rather than voltage driven and the conductivity distribution on the surface of the material greatly influences the bending performance. An accurate equivalent circuit modeling of the ionomer EAP performance is essential for the design of effective drive electronics. The ionomer main limitations are the fact that it needs to be moist continuously and the process of electrolysis that takes place during activation. An effective coating technique using a sprayed polymer was developed extending its operation in air from a few minutes to about four months. The coating technique effectively forms the equivalent of a skin to protect the moisture content of the ionomer. In parallel to the development of the bending EAP, the development of computer control of actuated longitudinal EAP has been pursued. An EAP driven miniature robotic arm was constructed and it is controlled by a MATLAB code to drop and lift the arm and close and open EAP fingers of a 4-finger gripper. Keywords: Miniature Robotics, Electroactive Polymers, Electroactive Actuators, EAP

  20. 77 FR 56710 - Proposed Information Collection (Veteran's Application for Compensation and/or Pension) Activity... (United States)


    ... Information Collection (Veteran's Application for Compensation and/or Pension) Activity: Comment Request... applicable, for compensation and/or pension benefit sought. DATES: Written comments and recommendations on... Compensation and/or Pension, VA Form 21-526. b. Veteran's Supplemental Claim Application, VA Form 21-526b. c...

  1. 76 FR 40451 - Agency Information Collection (Application for Ordinary Life Insurance) Activity Under OMB Review (United States)


    ... AFFAIRS Agency Information Collection (Application for Ordinary Life Insurance) Activity Under OMB Review... INFORMATION: Titles a. Application for Ordinary Life Insurance, Replacement Insurance for Modified Life Reduced at Age 65, National Service Life Insurance, VA Form 29-8485. b. Application for Ordinary Life...

  2. Wireless Technology Use Case Requirement Analysis for Future Space Applications (United States)

    Abedi, Ali; Wilkerson, DeLisa


    This report presents various use case scenarios for wireless technology -including radio frequency (RF), optical, and acoustic- and studies requirements and boundary conditions in each scenario. The results of this study can be used to prioritize technology evaluation and development and in the long run help in development of a roadmap for future use of wireless technology. The presented scenarios cover the following application areas: (i) Space Vehicles (manned/unmanned), (ii) Satellites and Payloads, (iii) Surface Explorations, (iv) Ground Systems, and (v) Habitats. The requirement analysis covers two parallel set of conditions. The first set includes the environmental conditions such as temperature, radiation, noise/interference, wireless channel characteristics and accessibility. The second set of requirements are dictated by the application and may include parameters such as latency, throughput (effective data rate), error tolerance, and reliability. This report provides a comprehensive overview of all requirements from both perspectives and details their effects on wireless system reliability and network design. Application area examples are based on 2015 NASA Technology roadmap with specific focus on technology areas: TA 2.4, 3.3, 5.2, 5.5, 6.4, 7.4, and 10.4 sections that might benefit from wireless technology.

  3. Application of transient analysis methodology to heat exchanger performance monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Rampall, I.; Soler, A.I.; Singh, K.P. [Holtec International, Cherry Hill, NJ (United States); Scott, B.H. [Baltimore Gas and Electric Co., Lusby, MD (United States)


    A transient testing technique is developed to evaluate the thermal performance of industrial scale heat exchangers. A Galerkin-based numerical method with a choice of spectral basis elements to account for spatial temperature variations in heat exchangers is developed to solve the transient heat exchanger model equations. Testing a heat exchanger in the transient state may be the only viable alternative where conventional steady state testing procedures are impossible or infeasible. For example, this methodology is particularly suited to the determination of fouling levels in component cooling water system heat exchangers in nuclear power plants. The heat load on these so-called component coolers under steady state conditions is too small to permit meaningful testing. An adequate heat load develops immediately after a reactor shutdown when the exchanger inlet temperatures are highly time-dependent. The application of the analysis methodology is illustrated herein with reference to an in-situ transient testing carried out at a nuclear power plant. The method, however, is applicable to any transient testing application.

  4. Orthogonal analysis of functional gold nanoparticles for biomedical applications. (United States)

    Tsai, De-Hao; Lu, Yi-Fu; DelRio, Frank W; Cho, Tae Joon; Guha, Suvajyoti; Zachariah, Michael R; Zhang, Fan; Allen, Andrew; Hackley, Vincent A


    We report a comprehensive strategy based on implementation of orthogonal measurement techniques to provide critical and verifiable material characteristics for functionalized gold nanoparticles (AuNPs) used in biomedical applications. Samples were analyzed before and after ≈50 months of cold storage (≈4 °C). Biomedical applications require long-term storage at cold temperatures, which could have an impact on AuNP therapeutics. Thiolated polyethylene glycol (SH-PEG)-conjugated AuNPs with different terminal groups (methyl-, carboxylic-, and amine-) were chosen as a model system due to their high relevancy in biomedical applications. Electrospray-differential mobility analysis, asymmetric-flow field flow fractionation, transmission electron microscopy, scanning electron microscopy, atomic force microscopy, inductively coupled plasma mass spectrometry, and small-angle X-ray scattering were employed to provide both complementary and orthogonal information on (1) particle size and size distribution, (2) particle concentrations, (3) molecular conjugation properties (i.e., conformation and surface packing density), and (4) colloidal stability. Results show that SH-PEGs were conjugated on the surface of AuNPs to form a brush-like polymer corona. The surface packing density of SH-PEG was ≈0.42 nm(-2) for the methyl-PEG-SH AuNPs, ≈0.26 nm(-2) for the amine-SH-PEG AuNPs, and ≈0.18 nm(-2) for the carboxylic-PEG-SH AuNPs before cold storage, approximately 10 % of its theoretical maximum value. The conformation of surface-bound SH-PEGs was then estimated to be in an intermediate state between brush-like and random-coiled, based on the measured thicknesses in liquid and in dry states. By analyzing the change in particle size distribution and number concentration in suspension following cold storage, the long term colloidal stability of AuNPs was shown to be significantly improved via functionalization with SH-PEG, especially in the case of methyl-PEG-SH and carboxylic

  5. Quantitative Structure-Activity Relationship Analysis of the ...

    African Journals Online (AJOL)

    Quantitative Structure-Activity Relationship Analysis of the Anticonvulsant Activity of Some Benzylacetamides Based on Genetic Algorithm-Based Multiple Linear Regression. ... Methods: AM1 semiempirical quantum chemical calculation method was used to find the optimum 3D geometry of the studied molecules. Two types ...

  6. Newspaper Coverage of Nigeria Police Activities: A Content Analysis

    African Journals Online (AJOL)

    This study is a content analysis of newspaper coverage of police activities in Nigeria from January to March, 2012. Three national dailies (the Nation, the Punch and Daily Sun) were studied. Among the specific objectives were to determine the volume of coverage of the activities of Nigeria Police by selected newspapers, ...

  7. Progress in Analysis to Remote Sensed Thermal Abnormity with Fault Activity and Seismogenic Process

    Directory of Open Access Journals (Sweden)

    WU Lixin


    Full Text Available Research to the remote sensed thermal abnormity with fault activity and seismogenic process is a vital topic of the Earth observation and remote sensing application. It is presented that a systematic review on the international researches on the topic during the past 30 years, in the respects of remote sensing data applications, anomaly analysis methods, and mechanism understanding. Firstly, the outlines of remote sensing data applications are given including infrared brightness temperature, microwave brightness temperature, outgoing longwave radiation, and assimilated data from multiple earth observations. Secondly, three development phases are summarized as qualitative analysis based on visual interpretation, quantitative analysis based on image processing, and multi-parameter spatio-temporal correlation analysis. Thirdly, the theoretical hypotheses presented for the mechanism understanding are introduced including earth degassing, stress-induced heat, crustal rock battery conversion, latent heat release due to radon decay as well as multi-spheres coupling effect. Finally, three key directions of future research on this topic are proposed:anomaly recognizing by remote sensing monitoring and data analysis for typical tectonic activity areas; anomaly mechanism understanding based on earthquake-related earth system responses; spatio-temporal correlation analysis of air-based, space-based and ground-based stereoscopic observations.


    Directory of Open Access Journals (Sweden)

    A. Sknar


    Full Text Available Contemporary economic science is looking for ways of research actualisation to resolve the challenges under the world financial crisis. Besides existing challenges in private de-regulated sector, one of the efficient innovations can be found in broadening ERP applications in the Public Sector. This paper approaches to the ERP applications mainly from the economical rather than from technical perspective. Comparative analysis of New Zealand public sector is supported by relevant international practical experience (implementations, and by core fundamental analysis of economical nature of business processes used by public entities. The key advantage (based on a historical timeline comes from a full integration of financial scope and operational activities. Using the example of ERP (as one of the drivers of productivity and performance improvement, the paper is aiming to underline how to bring the best practice and technology (data management and logical architecture from the private sector into the public sphere.

  9. Disentangling stereotype activation and stereotype application in the stereotype misperception task


    Krieglmeyer, R; Sherman, JW


    When forming impressions about other people, stereotypes about the individual's social group often influence the resulting impression. At least 2 distinguishable processes underlie stereotypic impression formation: stereotype activation and stereotype application. Most previous research has used implicit measures to assess stereotype activation and explicit measures to assess stereotype application, which has several disadvantages. The authors propose a measure of stereotypic impression forma...

  10. 26 CFR 1.145-2 - Application of private activity bond regulations. (United States)


    ... of the private business use test and the private security or payment test mean “5 percent” and “net... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Application of private activity bond regulations... Bonds § 1.145-2 Application of private activity bond regulations. (a) In general. Except as provided in...

  11. The Soil Moisture Active and Passive (SMAP) Mission: Improving Science Application Tools and Research (United States)

    Escobar, V. M.; Brown, M. E.; Moran, S. M.


    NASA depends on the science community to identify and prioritize leading-edge scientific questions and the observations required to answer them. The Soil Moisture Active and Passive (SMAP) Mission has been identified as a priority for NASA's Science Mission Directorate through the most recent decadal survey. Following launch in 2014, SMAP will deliver global maps of soil moisture content and surface freeze/thaw state. Global measurements of these variables are critical for terrestrial hydrologic and carbon cycle applications. The SMAP observatory consists of two multipolarization L-band sensors, a radar and radiometer that share a deployable mesh reflector antenna. The combined observations from the two sensors will allow accurate estimation of soil moisture at spatial scales. The wide-swath (1000 km) measurements will allow global mapping of soil moisture and freeze/thaw state with a 2-3 day revisit frequency and 1-2 day revisit in boreal latitudes. The synergy of active and passive observations enables measurements of soil moisture and freeze/thaw state with unprecedented resolution, sensitivity, area coverage and revisit frequency. SMAP data are valuable for both scientific research and practical applications. SMAP has the potential to drive a diverse range of novel research in drought and flood guidance, agricultural productivity estimation, weather forecasting, climate prediction, human health risk analysis and defense systems. The accuracy, resolution, and global coverage of SMAP soil moisture and freeze/thaw measurements will provide new information for many science and applications disciplines. A SMAP Applications Team will explore ways to measure interaction and integration of SMAP data with the Emergency Management User community of Maryland in order to produce quantitative metrics related to long-term projects, milestone completion, and movement of SMAP products into routine operations for emergency response.

  12. Canonical Correlation Analysis on Riemannian Manifolds and Its Applications. (United States)

    Kim, Hyunwoo J; Adluru, Nagesh; Bendlin, Barbara B; Johnson, Sterling C; Vemuri, Baba C; Singh, Vikas


    Canonical correlation analysis (CCA) is a widely used statistical technique to capture correlations between two sets of multi-variate random variables and has found a multitude of applications in computer vision, medical imaging and machine learning. The classical formulation assumes that the data live in a pair of vector spaces which makes its use in certain important scientific domains problematic. For instance, the set of symmetric positive definite matrices (SPD), rotations and probability distributions, all belong to certain curved Riemannian manifolds where vector-space operations are in general not applicable. Analyzing the space of such data via the classical versions of inference models is rather sub-optimal. But perhaps more importantly, since the algorithms do not respect the underlying geometry of the data space, it is hard to provide statistical guarantees (if any) on the results. Using the space of SPD matrices as a concrete example, this paper gives a principled generalization of the well known CCA to the Riemannian setting. Our CCA algorithm operates on the product Riemannian manifold representing SPD matrix-valued fields to identify meaningful statistical relationships on the product Riemannian manifold. As a proof of principle, we present results on an Alzheimer's disease (AD) study where the analysis task involves identifying correlations across diffusion tensor images (DTI) and Cauchy deformation tensor fields derived from T1-weighted magnetic resonance (MR) images.

  13. Supporting secure programming in web applications through interactive static analysis. (United States)

    Zhu, Jun; Xie, Jing; Lipford, Heather Richter; Chu, Bill


    Many security incidents are caused by software developers' failure to adhere to secure programming practices. Static analysis tools have been used to detect software vulnerabilities. However, their wide usage by developers is limited by the special training required to write rules customized to application-specific logic. Our approach is interactive static analysis, to integrate static analysis into Integrated Development Environment (IDE) and provide in-situ secure programming support to help developers prevent vulnerabilities during code construction. No additional training is required nor are there any assumptions on ways programs are built. Our work is motivated in part by the observation that many vulnerabilities are introduced due to failure to practice secure programming by knowledgeable developers. We implemented a prototype interactive static analysis tool as a plug-in for Java in Eclipse. Our technical evaluation of our prototype detected multiple zero-day vulnerabilities in a large open source project. Our evaluations also suggest that false positives may be limited to a very small class of use cases.

  14. Supporting secure programming in web applications through interactive static analysis

    Directory of Open Access Journals (Sweden)

    Jun Zhu


    Full Text Available Many security incidents are caused by software developers’ failure to adhere to secure programming practices. Static analysis tools have been used to detect software vulnerabilities. However, their wide usage by developers is limited by the special training required to write rules customized to application-specific logic. Our approach is interactive static analysis, to integrate static analysis into Integrated Development Environment (IDE and provide in-situ secure programming support to help developers prevent vulnerabilities during code construction. No additional training is required nor are there any assumptions on ways programs are built. Our work is motivated in part by the observation that many vulnerabilities are introduced due to failure to practice secure programming by knowledgeable developers. We implemented a prototype interactive static analysis tool as a plug-in for Java in Eclipse. Our technical evaluation of our prototype detected multiple zero-day vulnerabilities in a large open source project. Our evaluations also suggest that false positives may be limited to a very small class of use cases.

  15. VISPA. New applications for intuitive data visualisation and analysis creation

    Energy Technology Data Exchange (ETDEWEB)

    Erdmann, Martin; Fischer, Benjamin; Fischer, Robert; Glaser, Christian; Heidemann, Fabian; Mueller, Gero; Quast, Thorben; Rieger, Marcel; Urban, Martin; Asseldonk, Daniel van; Cube, Ralf Florian von; Welling, Christoph [Physics Institute IIIa, RWTH Aachen University (Germany)


    The Visual Physics Analysis software is a framework developed at RWTH Aachen providing intuitive access and usage of experiment-specific resources via common web browsers. Through its extension mechanism, VISPA allows for interfacing a wide range of applications to meet the demands for diverse use cases. After a quick review of the internal architecture and basic functionalities, most recent updates to the system are highlighted and various newly released extensions are presented: Our data browsers facilitate the inspection of information in Pierre Auger Observatory and HEP data samples. The JSROOT project has been embedded and enables the visualisation of ROOT files. Modular analysis chains based on our HEP software library (PXL) can be interactively created and modified using the Analysis Designer. VISPA is tested both through its integration in undergraduate and elementary particle physics courses at RWTH and through its use in analysis work for CMS and Auger. Finally, instructions on how to access our cluster or to set up an own server are given.

  16. Applied research of environmental monitoring using instrumental neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Young Sam; Moon, Jong Hwa; Chung, Young Ju


    This technical report is written as a guide book for applied research of environmental monitoring using Instrumental Neutron Activation Analysis. The contents are as followings; sampling and sample preparation as a airborne particulate matter, analytical methodologies, data evaluation and interpretation, basic statistical methods of data analysis applied in environmental pollution studies. (author). 23 refs., 7 tabs., 9 figs.

  17. Epiboron Neutron Activation Analysis with Nigeria Research Reactor

    African Journals Online (AJOL)

    Epiboron neutron activation analysis is optimized using Nigeria Research Reactor-1. Data are given for 6 elements using boron as shielding. Boron shield are of particular practical value for rapid instrumental analysis. Advantage factors for the following elements: I, Br, Cl, K, Mn and Na under boron shield are given.

  18. Activation of electrical machinery. Supplement 1. [Preliminary evaluation; not applicable to ground tests

    Energy Technology Data Exchange (ETDEWEB)

    Smolen, J.R.


    The following analysis of the induced radioactivity in SNAP-50/SPUR electrical machinery having a high cobalt content is submitted. Induced radioactivity in the flight vehicle will contribute negligibly to allowable radiation levels. This is especially so due to the low neutron to gamma ratio of assumed radiation damage tolerances to semiconductors. A calculation to estimate the order of magnitude of induced radioactivity in cobalt is attached. The calculation is based on a best guess of the neutron spectrum directly behind a lithium hydride shield. The resulting low cobalt activity and associated dose rate of about 1 mr/hr at 10 ft from a generator or a motor is insignificant. Although the evaluation indicates insignificant levels of induced radioactivity, this conclusion is not applicable to a ground test. Neutron moderation and scattering from a containment vessel and biological shield would greatly perturb the neutron environment behind the flight shield. Posttest handling of all components within the vacuum test chamber will undoubtedly be a problem. Notwithstanding the importance of limiting induced radioactivity, other considerations such as economy, cooling and vacuum requirements will largely dictate the final facility design. In summary, an activation analysis involves the overall facility design and will not be readily resolved. For a 10,000 hr. test the Co/sup 60/ activity may range from 100 curies per lb of cobalt where no shielding is provided to 10/sup -3/ curies per lb of cobalt where the equivalent of a flight shield is provided.

  19. Analysis of Low Temperature Organic Rankine Cycles for Solar Applications (United States)

    Li, Yunfei

    The present work focuses on Organic Rankine Cycle (ORC) systems and their application to low temperature waste heat recovery, combined heat and power as well as off-grid solar power generation applications. As CO_2 issues come to the fore front and fossil fuels become more expensive, interest in low grade heat recovery has grown dramatically in the past few years. Solar energy, as a clean, renewable, pollution-free and sustainable energy has great potential for the use of ORC systems. Several ORC solutions have been proposed to generate electricity from low temperature sources. The ORC systems discussed here can be applied to fields such as solar thermal, biological waste heat, engine exhaust gases, small-scale cogeneration, domestic boilers, etc. The current work presents a thermodynamic and economic analysis for the use of ORC systems to convert solar energy or low exergy energy to generate electrical power. The organic working fluids investigated here were selected to investigate the effect of the fluid saturation temperature on the performance of ORCs. The working fluids under investigation are R113, R245fa, R123, with boiling points between 40°C and 200°C at pressures from 10 kPa to 10 MPa. Ambient temperature air at 20oC to 30oC is utilized as cooling resource, and allowing for a temperature difference 10°C for effective heat transfer. Consequently, the working fluids are condensed at 40°C. A combined first- and second-law analysis is performed by varying some system independent parameters at various reference temperatures. The present work shows that ORC systems can be viable and economical for the applications such as waste heat use and off-grid power generation even though they are likely to be more expensive than grid power.

  20. Spatial heterogeneity analysis of brain activation in fMRI

    Directory of Open Access Journals (Sweden)

    Lalit Gupta


    Full Text Available In many brain diseases it can be qualitatively observed that spatial patterns in blood oxygenation level dependent (BOLD activation maps appear more (diffusively distributed than in healthy controls. However, measures that can quantitatively characterize this spatial distributiveness in individual subjects are lacking. In this study, we propose a number of spatial heterogeneity measures to characterize brain activation maps. The proposed methods focus on different aspects of heterogeneity, including the shape (compactness, complexity in the distribution of activated regions (fractal dimension and co-occurrence matrix, and gappiness between activated regions (lacunarity. To this end, functional MRI derived activation maps of a language and a motor task were obtained in language impaired children with (Rolandic epilepsy and compared to age-matched healthy controls. Group analysis of the activation maps revealed no significant differences between patients and controls for both tasks. However, for the language task the activation maps in patients appeared more heterogeneous than in controls. Lacunarity was the best measure to discriminate activation patterns of patients from controls (sensitivity 74%, specificity 70% and illustrates the increased irregularity of gaps between activated regions in patients. The combination of heterogeneity measures and a support vector machine approach yielded further increase in sensitivity and specificity to 78% and 80%, respectively. This illustrates that activation distributions in impaired brains can be complex and more heterogeneous than in normal brains and cannot be captured fully by a single quantity. In conclusion, heterogeneity analysis has potential to robustly characterize the increased distributiveness of brain activation in individual patients.

  1. Application of paper spray ionization for explosives analysis. (United States)

    Tsai, Chia-Wei; Tipple, Christopher A; Yost, Richard A


    A desired feature in the analysis of explosives is to decrease the time of the entire analysis procedure, including sampling. A recently utilized ambient ionization technique, paper spray ionization (PSI), provides the possibility of combining sampling and ionization. However, an interesting phenomenon that occurs in generating negatively charged ions pose some challenges in applying PSI to explosives analysis. The goal of this work is to investigate the possible solutions for generating explosives ions in negative mode PSI. The analysis of 2,4,6-trinitrotoluene (TNT), pentaerythritol tetranitrate (PETN), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) was performed. Several solvent systems with different surface tensions and additives were compared to determine their effect on the ionization of explosives. The solvents tested include tert-butanol, isopropanol, methanol, and acetonitrile. The additives tested were carbon tetrachloride and ammonium nitrate. Of the solvents tested, isopropanol yielded the best results. In addition, adding ammonium nitrate to the isopropanol enhanced the analyte signal. Experimentally determined limits of detection (LODs) as low as 0.06 ng for PETN, on paper, were observed with isopropanol and the addition of 0.4 mM ammonium nitrate as the spray solution. In addition, the explosive components of two plastic explosive samples, Composition 4 and Semtex, were successfully analyzed via surface sampling when using the developed method. The analysis of explosives using PSI-MS in negative ion mode was achieved. The addition of ammonium nitrate to isopropanol, in general, enhanced the analyte signal and yielded better ionization stability. Real-world explosive samples were analyzed, which demonstrates one of the potential applications of PSI-MS analysis. Copyright © 2017 John Wiley & Sons, Ltd.

  2. Modeling the Benchmark Active Control Technology Wind-Tunnel Model for Application to Flutter Suppression (United States)

    Waszak, Martin R.


    This paper describes the formulation of a model of the dynamic behavior of the Benchmark Active Controls Technology (BACT) wind-tunnel model for application to design and analysis of flutter suppression controllers. The model is formed by combining the equations of motion for the BACT wind-tunnel model with actuator models and a model of wind-tunnel turbulence. The primary focus of this paper is the development of the equations of motion from first principles using Lagrange's equations and the principle of virtual work. A numerical form of the model is generated using values for parameters obtained from both experiment and analysis. A unique aspect of the BACT wind-tunnel model is that it has upper- and lower-surface spoilers for active control. Comparisons with experimental frequency responses and other data show excellent agreement and suggest that simple coefficient-based aerodynamics are sufficient to accurately characterize the aeroelastic response of the BACT wind-tunnel model. The equations of motion developed herein have been used to assist the design and analysis of a number of flutter suppression controllers that have been successfully implemented.

  3. Modeling, analysis, control and design application guidelines of Doubly Fed Induction Generator (DFIG) for wind power applications (United States)

    Masaud, Tarek

    Double Fed Induction Generators (DFIG) has been widely used for the past two decades in large wind farms. However, there are many open-ended problems yet to be solved before they can be implemented in some specific applications. This dissertation deals with the general analysis, modeling, control and applications of the DFIG for large wind farm applications. A detailed "d-q" model of DFIG along with other applications is simulated using the MATLAB/Simulink platform. The simulation results have been discussed in detail in both sub-synchronous and super-synchronous mode of operation. An improved vector control strategy based on the rotor flux oriented vector control has been proposed to control the active power output of the DFIG. The new vector control strategy is compared with the stator flux oriented vector control which is commonly used. It is observed that the new improved vector control method provides a better active power tracking accuracy compare with the stator flux oriented vector control. The behavior of the DFIG -based wind farm under the various grid disturbances is also studied in this dissertation. The implementation of the Flexible AC Transmission System devices (FACTS) to overcome the voltage stability issue for such applications is investigated. The study includes the implementation of both a static synchronous compensator (STATCOM), and the static VAR compensator (SVC) as dynamic reactive power compensators at the point of common coupling to support DFIG-based wind farm during disturbances. Integrating FACTS protect the grid connected DFIG-based wind farm from going offline during and after the disturbances. It is found that the both devices improve the transient performance and therefore helps the wind turbine generator system to remain in service during grid faults. A comparison between the performance of the two devices in terms of the amount of reactive power injected, time response and the application cost has been discussed in this



    R Fiza Anwar Sharif1, Kudang Boro Seminar2*, Arief Ramadhan3


    One of the critical requirements of Yellow Pages Mobile Applications is the ability to process and to analyse big data acquired from massive activity logs generated by Yellow Pages Mobile applications. Conventional computing and storage model is no longer compatible to handle big data processing . This research is aimed to develop a proptoype of event stream processing activity logger for mobile applications that can be implemented and aligned with current technological developments. The pr...

  5. Active Flow Control on Bidirectional Rotors for Tidal MHK Applications

    Energy Technology Data Exchange (ETDEWEB)

    Shiu, Henry [Research Engineer; van Dam, Cornelis P. [Professor


    A marine and hydrokinetic (MHK) tidal turbine extracts energy from tidal currents, providing clean, sustainable electricity generation. In general, all MHK conversion technologies are confronted with significant operational hurdles, resulting in both increased capital and operations and maintenance (O&M) costs. To counter these high costs while maintaining reliability, MHK turbine designs can be simplified. Prior study found that a tidal turbine could be cost-effectively simplified by removing blade pitch and rotor/nacelle yaw. Its rotor would run in one direction during ebb and then reverse direction when the current switched to flood. We dubbed such a turbine a bidirectional rotor tidal turbine (BRTT). The bidirectional hydrofoils of a BRTT are less efficient than conventional hydrofoils and capture less energy, but the elimination of the pitch and yaw systems were estimated to reduce levelized cost of energy by 7.8%-9.6%. In this study, we investigated two mechanisms for recapturing some of the performance shortfall of the BRTT. First, we developed a novel set of hydrofoils, designated the yy series, for BRTT application. Second, we investigated the use of active flow control via microtabs. Microtabs are small deployable/retractable tabs, typically located near the leading or trailing edge of an air/hydrofoil with height on the order of the boundary layer thickness (1% - 2% of chord). They deploy approximately perpendicularly to the foil surface and, like gurney flaps and plain flaps, globally affect the aerodynamics of the airfoil. By strategically placing microtabs and selectively deploying them based on the direction of the inflow, performance of a BRTT rotor can be improved while retaining bidirectional operation. The yy foils were computationally designed and analyzed. They exhibited better performance than the baseline bidirectional foil, the ellipse. For example, the yyb07cn-180 had 14.7% higher (l/d)max than an ellipse of equal thickness. The yyb07cn

  6. Application of the Monte Carlo method to estimate doses due to neutron activation of different materials in a nuclear reactor (United States)

    Ródenas, José


    All materials exposed to some neutron flux can be activated independently of the kind of the neutron source. In this study, a nuclear reactor has been considered as neutron source. In particular, the activation of control rods in a BWR is studied to obtain the doses produced around the storage pool for irradiated fuel of the plant when control rods are withdrawn from the reactor and installed into this pool. It is very important to calculate these doses because they can affect to plant workers in the area. The MCNP code based on the Monte Carlo method has been applied to simulate activation reactions produced in the control rods inserted into the reactor. Obtained activities are introduced as input into another MC model to estimate doses produced by them. The comparison of simulation results with experimental measurements allows the validation of developed models. The developed MC models have been also applied to simulate the activation of other materials, such as components of a stainless steel sample introduced into a training reactors. These models, once validated, can be applied to other situations and materials where a neutron flux can be found, not only nuclear reactors. For instance, activation analysis with an Am-Be source, neutrography techniques in both medical applications and non-destructive analysis of materials, civil engineering applications using a Troxler, analysis of materials in decommissioning of nuclear power plants, etc.

  7. An analysis of a board game as a treatment activity. (United States)

    Neistadt, M E; McAuley, D; Zecha, D; Shannon, R


    Occupational therapists often use tabletop board games in treatment to help adult clients with physical disabilities improve the perceptual, cognitive, sensory, and fine motor skill components of occupational behavior. Detailed activity analyses of these types of activities, including performance norms, are not available in the occupational therapy literature. Such analyses would help therapists consider the multiple skill demands of tabletop games and allow more systematic grading of these treatment activities. This paper presents a model for analyzing therapeutic activities in relation to relevant motor learning and cognitive-perceptual literature. Included in this analysis are a description of the activity, examination of its component skills and of the qualitative features of activity performance, suggestions for grading and for treatment goals, and some preliminary performance standards derived from a pilot study of 18 adults without physical disabilities. The issue of transfer of skills between games and functional activities is also discussed.

  8. Activities of invertase and cellulase as influenced by the application ...

    African Journals Online (AJOL)

    A laboratory experiment was conducted to study the effect of selected fungicides, tridemorph and captan, at concentrations ranging from 0 to10 kg ha-1 on the activity of invertase and cellulase in a vertisol. The activities of invertase and cellulase were significantly more at tridemorph and captan levels of 2.5 and 5.0 kg ha-1, ...

  9. Lipidomic data analysis: tutorial, practical guidelines and applications. (United States)

    Checa, Antonio; Bedia, Carmen; Jaumot, Joaquim


    Lipids are a broad group of biomolecules involved in diverse critical biological roles such as cellular membrane structure, energy storage or cell signaling and homeostasis. Lipidomics is the -omics science that pursues the comprehensive characterization of lipids present in a biological sample. Different analytical strategies such as nuclear magnetic resonance or mass spectrometry with or without previous chromatographic separation are currently used to analyze the lipid composition of a sample. However, current analytical techniques provide a vast amount of data which complicates the interpretation of results without the use of advanced data analysis tools. The choice of the appropriate chemometric method is essential to extract valuable information from the crude data as well as to interpret the lipidomic results in the biological context studied. The present work summarizes the diverse methods of analysis than can be used to study lipidomic data, from statistical inference tests to more sophisticated multivariate analysis methods. In addition to the theoretical description of the methods, application of various methods to a particular lipidomic data set as well as literature examples are presented. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Application of Social Network Analysis for Livelihood System Study

    Directory of Open Access Journals (Sweden)

    Sanchayeeta Misra


    Full Text Available Social Network Analysis (SNA has received growing attention among diverse academic fields for studying ‘social relations’ among individuals and institutions. Unfortunately, its application has remained limited in the study of livelihood systems of rural poor. Complexity in rural livelihoods has increased sharply in the face of increased pressure on natural resources and rapid shift in farm-based to non-farm based employments. This poses great challenge to successful livelihood intervention in rural areas. On one hand, rural development/extension needs to cater to diverse information and service need of the rural people; on other hand, rural institutions need to deliver livelihood-sustaining services more efficiently, which often need institutional restructuring at multiple levels. To achieve these challenges, a strong innovative analytical tool is required for understanding the complexity of rural livelihoods and the associated role of rural institutions. SNA provides excellent scope to analyse such complex systems and interactions among their components. This article proposes an outline of using SNA in livelihood system analysis. The analysis can provide answer to many questions of practical importance – Who are the influential actors in a livelihood system? Which are the key institutions contributing towards sustainable livelihoods? How do these actors interact among themselves? This will help rural development administrators to deliver livelihood-supporting services more efficiently through informed targeting and capacity building.

  11. Analysis of Camera Arrays Applicable to the Internet of Things. (United States)

    Yang, Jiachen; Xu, Ru; Lv, Zhihan; Song, Houbing


    The Internet of Things is built based on various sensors and networks. Sensors for stereo capture are essential for acquiring information and have been applied in different fields. In this paper, we focus on the camera modeling and analysis, which is very important for stereo display and helps with viewing. We model two kinds of cameras, a parallel and a converged one, and analyze the difference between them in vertical and horizontal parallax. Even though different kinds of camera arrays are used in various applications and analyzed in the research work, there are few discussions on the comparison of them. Therefore, we make a detailed analysis about their performance over different shooting distances. From our analysis, we find that the threshold of shooting distance for converged cameras is 7 m. In addition, we design a camera array in our work that can be used as a parallel camera array, as well as a converged camera array and take some images and videos with it to identify the threshold.

  12. Application Specific MMICs for Advanced Active Phased-Array Antenna's

    NARCIS (Netherlands)

    Bogaart, F.L.M. van den


    Some application specific MMIC solutions, developed at TNO-FEL, are presented. These MMICs address the needs for future phased-array architectures. Among the MMICs are: a wide-band high-efficiency power amplifier in a MESFET technology, integrated tuneable microwave filters and multifunction RF

  13. Mobile health applications to promote active and healthy ageing

    NARCIS (Netherlands)

    Helbostad, Jorunn L.; Vereijken, Beatrix; Becker, Clemens; Todd, Christop; Taraldsen, Kristin; Pijnappels, Mirjam; Aminian, Kamiar; Mellone, Sabato


    The European population is ageing, and there is a need for health solutions that keep older adults independent longer. With increasing access to mobile technology, such as smartphones and smartwatches, the development and use of mobile health applications is rapidly growing. To meet the societal

  14. Monte-Carlo Application for Nondestructive Nuclear Waste Analysis (United States)

    Carasco, C.; Engels, R.; Frank, M.; Furletov, S.; Furletova, J.; Genreith, C.; Havenith, A.; Kemmerling, G.; Kettler, J.; Krings, T.; Ma, J.-L.; Mauerhofer, E.; Neike, D.; Payan, E.; Perot, B.; Rossbach, M.; Schitthelm, O.; Schumann, M.; Vasquez, R.


    Radioactive waste has to undergo a process of quality checking in order to check its conformance with national regulations prior to its transport, intermediate storage and final disposal. Within the quality checking of radioactive waste packages non-destructive assays are required to characterize their radio-toxic and chemo-toxic contents. The Institute of Energy and Climate Research - Nuclear Waste Management and Reactor Safety of the Forschungszentrum Jülich develops in the framework of cooperation nondestructive analytical techniques for the routine characterization of radioactive waste packages at industrial-scale. During the phase of research and development Monte Carlo techniques are used to simulate the transport of particle, especially photons, electrons and neutrons, through matter and to obtain the response of detection systems. The radiological characterization of low and intermediate level radioactive waste drums is performed by segmented γ-scanning (SGS). To precisely and accurately reconstruct the isotope specific activity content in waste drums by SGS measurement, an innovative method called SGSreco was developed. The Geant4 code was used to simulate the response of the collimated detection system for waste drums with different activity and matrix configurations. These simulations allow a far more detailed optimization, validation and benchmark of SGSreco, since the construction of test drums covering a broad range of activity and matrix properties is time consuming and cost intensive. The MEDINA (Multi Element Detection based on Instrumental Neutron Activation) test facility was developed to identify and quantify non-radioactive elements and substances in radioactive waste drums. MEDINA is based on prompt and delayed gamma neutron activation analysis (P&DGNAA) using a 14 MeV neutron generator. MCNP simulations were carried out to study the response of the MEDINA facility in terms of gamma spectra, time dependence of the neutron energy spectrum

  15. Comparative Analysis Of Conventional Method With Activity Based Costing In PT Mulia Sejati Gallery

    Directory of Open Access Journals (Sweden)

    Irma Nadia Erena


    Full Text Available The goal of this research was to provide readers the information about the calculation methods, both traditional and activity-based costing in the application of the cost of production. The method used in this research was the qualitative method. The analysis was done by calculating the amount of the production cost using the traditional system and the magnitude of the production cost when using the activity-based costing system. The amount of each acquisition was then performed into data analysis. The results achieved are massive distortion between the calculations using traditional systems and activity based costing system. The conclusions of the whole thesis are activity-based costing system is considered more relevant than traditional systems that are currently used by the company.

  16. Neutron activation analysis with k{sub 0}-standardisation : general formalism and procedure

    Energy Technology Data Exchange (ETDEWEB)

    Pomme, S.; Hardeman, F. [Centre de l`Etude de l`Energie Nucleaire, Mol (Belgium); Robouch, P.; Etxebarria, N.; Arana, G. [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (Belgium)


    Instrumental neutron activation analysis (INAA) with k{sub 0}-standardisation is a powerful tool for multi-element analysis at a broad range of trace element concentrations. An overview is given of the basic principles, fundamental equations, and general procedure of this method. Different aspects of the description of the neutron activation reaction rate are discussed, applying the Hogdahl convention. A general activation-decay formula is derived and its application to INAA is demonstrated. Relevant k{sub 0}-definitions for different activation decay schemes are summarised and upgraded to cases of extremely high fluxes. The main standardisation techniques for INAA are discussed, emphasizing the k{sub 0}-standardisation. Some general aspects of the basic equipment and its calibration are discussed, such as the characterisation of the neutron field and the tuning of the spectrometry part. A method for the prediction and optimisation of the analytical performance of INAA is presented.

  17. Application of quantum cascade lasers to trace gas analysis (United States)

    Kosterev, A.; Wysocki, G.; Bakhirkin, Y.; So, S.; Lewicki, R.; Fraser, M.; Tittel, F.; Curl, R. F.


    Quantum cascade (QC) lasers are virtually ideal mid-infrared sources for trace gas monitoring. They can be fabricated to operate at any of a very wide range of wavelengths from ˜ 3 μm to ˜ 24 μm. Seizing the opportunity presented by mid-infrared QC lasers, several groups world-wide are actively applying them to trace gas sensing. Real world applications include environmental monitoring, industrial process control and biomedical diagnostics. In our laboratory we have explored the use of several methods for carrying out absorption spectroscopy with these sources, which include multipass absorption spectroscopy, cavity ring down spectroscopy (CRDS), integrated cavity output spectroscopy (ICOS), and quartz-enhanced photoacoustic spectroscopy (QEPAS).

  18. Network DEA: an application to analysis of academic performance (United States)

    Saniee Monfared, Mohammad Ali; Safi, Mahsa


    As governmental subsidies to universities are declining in recent years, sustaining excellence in academic performance and more efficient use of resources have become important issues for university stakeholders. To assess the academic performances and the utilization of the resources, two important issues need to be addressed, i.e., a capable methodology and a set of good performance indicators as we consider in this paper. In this paper, we propose a set of performance indicators to enable efficiency analysis of academic activities and apply a novel network DEA structure to account for subfunctional efficiencies such as teaching quality, research productivity, as well as the overall efficiency. We tested our approach on the efficiency analysis of academic colleges at Alzahra University in Iran.

  19. Analysis and application of analog electronic circuits to biomedical instrumentation

    CERN Document Server

    Northrop, Robert B


    This book introduces the basic mathematical tools used to describe noise and its propagation through linear systems and provides a basic description of the improvement of signal-to-noise ratio by signal averaging and linear filtering. The text also demonstrates how op amps are the keystone of modern analog signal conditioning systems design, and illustrates their use in isolation and instrumentation amplifiers, active filters, and numerous biomedical instrumentation systems and subsystems. It examines the properties of the ideal op amp and applies this model to the analysis of various circuits

  20. Application of stir bar sorptive extraction for wine analysis. (United States)

    Hayasaka, Yoji; MacNamara, Kevin; Baldock, Gayle A; Taylor, Randell L; Pollnitz, Alan P


    Stir bar sorptive extraction (SBSE) coupled with gas chromatography/mass spectrometry (GC/MS) was used to analyse wine samples for three applications: flavour and compositional analysis; 2,4,6-trichloroanisole (TCA), a common off-aroma in wine; and agrochemicals. SBSE was found to be orders of magnitude more sensitive than modern conventional methodology, allowing for lower detection and quantitation levels, and improved confirmation of identity; SBSE often gave better signal to noise in scan mode than other methods in selective ion monitoring (SIM) mode. With the help of their characteristic mass spectra all agrochemicals could be identified unambiguously at concentrations of 10 microg L(-1) in wine and a further 100 constituents were detected in a Cabernet Sauvignon sample. Thus it is now possible to analyse complex samples such as wine by scan mode, with better confirmation of identity, and without sacrificing sensitivity, where previously SIM methodology had to be used.

  1. Application of Sensitivity Analysis in Design of Sustainable Buildings

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik; Brohus, Henrik


    Building performance can be expressed by different indicators such as primary energy use, environmental load and/or the indoor environmental quality and a building performance simulation can provide the decision maker with a quantitative measure of the extent to which an integrated design solutio...... possible to influence the most important design parameters. A methodology of sensitivity analysis is presented and an application example is given for design of an office building in Denmark....... satisfies the design objectives and criteria. In the design of sustainable buildings, it is beneficial to identify the most important design parameters in order to more efficiently develop alternative design solutions or reach optimized design solutions. Sensitivity analyses make it possible to identify...... the most important parameters in relation to building performance and to focus design and optimization of sustainable buildings on these fewer, but most important parameters. The sensitivity analyses will typically be performed at a reasonably early stage of the building design process, where it is still...

  2. Normal mode analysis and applications in biological physics. (United States)

    Dykeman, Eric C; Sankey, Otto F


    Normal mode analysis has become a popular and often used theoretical tool in the study of functional motions in enzymes, viruses, and large protein assemblies. The use of normal modes in the study of these motions is often extremely fruitful since many of the functional motions of large proteins can be described using just a few normal modes which are intimately related to the overall structure of the protein. In this review, we present a broad overview of several popular methods used in the study of normal modes in biological physics including continuum elastic theory, the elastic network model, and a new all-atom method, recently developed, which is capable of computing a subset of the low frequency vibrational modes exactly. After a review of the various methods, we present several examples of applications of normal modes in the study of functional motions, with an emphasis on viral capsids.

  3. Experiment and Analysis of Car Alternator for Wind Turbine Application

    Directory of Open Access Journals (Sweden)

    Pudji Irasari


    Full Text Available This paper discusses experiment and analysis to find out the feasibility of a car alternator to be used as a generator for wind turbine. The experiment was conducted twice. The first experiment was to characterize the alternator to determine the mechanical transmission ratio. In this experiment the alternator was driven by a lathe machine and its output power was supplied to charge a battery. In the second experiment the alternator was integrated with the turbine blades and they were tested as a unit system. In both experiments, the electric generation of alternator was executed with fixed excitation current method. The correlation between the alternator characteristic and the tip speed ratio gives the mechanical transmission ratio of 1 : 3. The experiment results show that the efficiency of alternator is around 50% and cut-in wind speed (after correction is 6.35 m/s indicating that alternator is not feasible for wind turbine system application

  4. Some Logical Metatheorems with Applications in Functional Analysis

    DEFF Research Database (Denmark)

    Kohlenbach, Ulrich


    In previous papers we have developed proof-theoretic techniques for extracting effective uniform bounds from large classes of ineffective existence proofs in functional analysis. Here `uniform' means independence from parameters in compact spaces. A recent case study in fixed-point theory...... systematically yielded uniformity even w.r.t. parameters in metrically bounded (but noncompact) subsets which had been known before only in special cases. In the present paper we prove general logical metatheorems which cover these applications to fixed-point theory as special cases but are not restricted...... to this area at all. Our theorems guarantee under general logical conditions such strong uniform versions of non-uniform existence statements. Moreover, they provide algorithms for actually extracting effective uniform bounds and transforming the original proof into one for the stronger uniformity result. Our...

  5. GPU-based Integration with Application in Sensitivity Analysis (United States)

    Atanassov, Emanouil; Ivanovska, Sofiya; Karaivanova, Aneta; Slavov, Dimitar


    The presented work is an important part of the grid application MCSAES (Monte Carlo Sensitivity Analysis for Environmental Studies) which aim is to develop an efficient Grid implementation of a Monte Carlo based approach for sensitivity studies in the domains of Environmental modelling and Environmental security. The goal is to study the damaging effects that can be caused by high pollution levels (especially effects on human health), when the main modeling tool is the Danish Eulerian Model (DEM). Generally speaking, sensitivity analysis (SA) is the study of how the variation in the output of a mathematical model can be apportioned to, qualitatively or quantitatively, different sources of variation in the input of a model. One of the important classes of methods for Sensitivity Analysis are Monte Carlo based, first proposed by Sobol, and then developed by Saltelli and his group. In MCSAES the general Saltelli procedure has been adapted for SA of the Danish Eulerian model. In our case we consider as factors the constants determining the speeds of the chemical reactions in the DEM and as output a certain aggregated measure of the pollution. Sensitivity simulations lead to huge computational tasks (systems with up to 4 × 109 equations at every time-step, and the number of time-steps can be more than a million) which motivates its grid implementation. MCSAES grid implementation scheme includes two main tasks: (i) Grid implementation of the DEM, (ii) Grid implementation of the Monte Carlo integration. In this work we present our new developments in the integration part of the application. We have developed an algorithm for GPU-based generation of scrambled quasirandom sequences which can be combined with the CPU-based computations related to the SA. Owen first proposed scrambling of Sobol sequence through permutation in a manner that improves the convergence rates. Scrambling is necessary not only for error analysis but for parallel implementations. Good scrambling is

  6. User needs and requirements analysis for big data healthcare applications. (United States)

    Zillner, Sonja; Lasierra, Nelia; Faix, Werner; Neururer, Sabrina


    The realization of big data applications that allow improving the quality and efficiency of healthcare care delivery is challenging. In order to take advantage of the promising opportunities of big data technologies, a clear understanding of user needs and requirements of the various stakeholders of healthcare, such as patients, clinicians and physicians, healthcare provider, payors, pharmaceutical industry, medical product suppliers and government, is needed. Our study is based on internet, literature and market study research as well as on semi-structured interviews with major stakeholder groups of healthcare delivery settings. The analysis shows that big data technologies could be used to align the opposing user needs of improved quality with improved efficiency of care. However, this requires the integrated view of various heterogeneous data sources, legal frameworks for data sharing and incentives that foster collaboration.

  7. Prior art relevant to active beads patent application

    CSIR Research Space (South Africa)

    Moolman, S


    Full Text Available products: shell comprising glassy state carbohydrate (e.g. sucrose, glucose, fructose, sorbitol, maltitol, xylitol, etc) & core comprising flavourings, oil-based materials or confectionery fillings. US 5,855,826 Encapsulates fat-soluble actives...

  8. Evaluation of harmonic detection methods for active power filter applications

    DEFF Research Database (Denmark)

    Asiminoaei, Lucian; Blaabjerg, Frede; Hansen, Steffan


    In the attempt to minimize the harmonic disturbances created by the non-linear loads the choice of the active power filters comes out to improve the filtering efficiency and to solve many issues existing with classical passive filters. One of the key points for a proper implementation of an active...... implementation issues. The conclusions are collected and a comparison is given at the end, which is useful in deciding the future hardware setup implementation. The comparison shows that the choice of numerical filtering is a key factor for obtaining good accuracies and dynamics for an active filter....... theories. Then, the work here proposes a simulation setup that decouples the harmonic reference generator from the active filter model and its controller. In this way the selected methods can be equally analyzed and compared with respect to their performance, which helps anticipating possible...

  9. Condition Monitoring Of Operating Pipelines With Operational Modal Analysis Application

    Directory of Open Access Journals (Sweden)

    Mironov Aleksey


    Full Text Available In the petroleum, natural gas and petrochemical industries, great attention is being paid to safety, reliability and maintainability of equipment. There are a number of technologies to monitor, control, and maintain gas, oil, water, and sewer pipelines. The paper focuses on operational modal analysis (OMA application for condition monitoring of operating pipelines. Special focus is on the topicality of OMA for definition of the dynamic features of the pipeline (frequencies and mode shapes in operation. The research was conducted using two operating laboratory models imitated a part of the operating pipeline. The results of finite-element modeling, identification of pipe natural modes and its modification under the influence of virtual failure are discussed. The work considers the results of experimental research of dynamic behavior of the operating pipe models using one of OMA techniques and comparing dynamic properties with the modeled data. The study results demonstrate sensitivity of modal shape parameters to modification of operating pipeline technical state. Two strategies of pipeline repair – with continuously condition-based monitoring with proposed technology and without such monitoring, was discussed. Markov chain reliability models for each strategy were analyzed and reliability improvement factor for proposed technology of monitoring in compare with traditional one was evaluated. It is resumed about ability of operating pipeline condition monitoring by measuring dynamic deformations of the operating pipe and OMA techniques application for dynamic properties extraction.

  10. [Methods and applications of population viability analysis (PVA): a review]. (United States)

    Tian, Yu; Wu, Jian-Guo; Kou, Xiao-Jun; Wang, Tian-Ming; Smith, Andrew T; Ge, Jian-Ping


    With the accelerating human consumption of natural resources, the problems associated with endangered species caused by habitat loss and fragmentation have become greater and more urgent than ever. Conceptually associated with the theories of island biogeography, population viability analysis (PVA) has been one of the most important approaches in studying and protecting endangered species, and this methodology has occupied a central place in conservation biology and ecology in the past several decades. PVA has been widely used and proven effective in many cases, but its predictive ability and accuracy are still in question. Also, its application needs expand. To overcome some of the problems, we believe that PVA needs to incorporate some principles and methods from other fields, particularly landscape ecology and sustainability science. Integrating landscape pattern and socioeconomic factors into PVA will make the approach theoretically more comprehensive and practically more useful. Here, we reviewed the history, basic conception, research methods, and modeling applications and their accuracies of PVA, and proposed the perspective in this field.

  11. GPS Data Filtration Method for Drive Cycle Analysis Applications

    Energy Technology Data Exchange (ETDEWEB)

    Duran, A.; Earleywine, M.


    When employing GPS data acquisition systems to capture vehicle drive-cycle information, a number of errors often appear in the raw data samples, such as sudden signal loss, extraneous or outlying data points, speed drifting, and signal white noise, all of which limit the quality of field data for use in downstream applications. Unaddressed, these errors significantly impact the reliability of source data and limit the effectiveness of traditional drive-cycle analysis approaches and vehicle simulation software. Without reliable speed and time information, the validity of derived metrics for drive cycles, such as acceleration, power, and distance, become questionable. This study explores some of the common sources of error present in raw onboard GPS data and presents a detailed filtering process designed to correct for these issues. Test data from both light and medium/heavy duty applications are examined to illustrate the effectiveness of the proposed filtration process across the range of vehicle vocations. Graphical comparisons of raw and filtered cycles are presented, and statistical analyses are performed to determine the effects of the proposed filtration process on raw data. Finally, an evaluation of the overall benefits of data filtration on raw GPS data and present potential areas for continued research is presented.

  12. Crossing trend analysis methodology and application for Turkish rainfall records (United States)

    Şen, Zekâi


    Trend analyses are the necessary tools for depicting possible general increase or decrease in a given time series. There are many versions of trend identification methodologies such as the Mann-Kendall trend test, Spearman's tau, Sen's slope, regression line, and Şen's innovative trend analysis. The literature has many papers about the use, cons and pros, and comparisons of these methodologies. In this paper, a completely new approach is proposed based on the crossing properties of a time series. It is suggested that the suitable trend from the centroid of the given time series should have the maximum number of crossings (total number of up-crossings or down-crossings). This approach is applicable whether the time series has dependent or independent structure and also without any dependence on the type of the probability distribution function. The validity of this method is presented through extensive Monte Carlo simulation technique and its comparison with other existing trend identification methodologies. The application of the methodology is presented for a set of annual daily extreme rainfall time series from different parts of Turkey and they have physically independent structure.

  13. Comparative Analysis of Western and Domestic Practice of Interactive Method Application in Teaching Social and Political Disciplines at the Universities (United States)

    Hladka, Halyna


    The comparative analysis of western and domestic practice of introducing active and interactive methods of studies in the process of teaching social science disciplines has been carried out. Features, realities, prospects and limitations in application of interactive methods of teaching in the process of implementing social-political science…

  14. FPGA applications for single dish activity at Medicina radio telescopes (United States)

    Bartolin, M.; Nald, G.; Mattan, A.; Maccaferr, A.; De Biagg, M.

    FPGA technologies are gaining major attention in the recent years in the field of radio astronomy. At Medicina radio telescopes, FPGAs have been used in the last ten years for a number of purposes and in this article we will take into exam the applications developed and installed for the Medicina Single Dish 32m Antenna: these range from high performance digital signal processing to instrument control developed on top of smaller FPGAs.

  15. Calmodulin-binding transcription activators and perspectives for applications in biotechnology. (United States)

    Shen, Chenjia; Yang, Yanjun; Du, Liqun; Wang, Huizhong


    In recent years, a novel family of calmodulin-binding transcription activators (CAMTAs) has been reported in various species. The CAMTAs share a conserved domain organization, with a CG-1 DNA-binding domain, a transcription factor immunoglobulin domain, several ankyrin repeats, a calmodulin-binding domain, and a varying number of IQ motifs. CAMTAs participate in transcriptional regulation by recognizing and binding to a specific cis-element: (G/A/C)CGCG(C/G/T). Plants suffer from the environmental challenges, including abiotic and biotic stresses. Investigations in various plant species indicate a broad range of CAMTA functions involved in developmental regulation, environmental stress response, and hormone cross talk. In this review, we focus on the expression patterns and biological functions of CAMTAs to explore their probable applications in biotechnology. Furthermore, the identification and phylogenetic analysis of CAMTAs in crops could open new perspectives for enhancing stress tolerance, which could lead to improved crop production.


    Directory of Open Access Journals (Sweden)

    M. Watagawa


    Full Text Available The Advanced Land Observing Satellite (ALOS was launched for earth observation and there are more than 6 million scenes of archives including coastal areas during period of five years. The wealth of satellite imagery is noticeable for investigating monitoring methods such as ship detection in wide ocean area. Especially, it is useful way to estimate past behaviour from satellite imagery compared to reference data. We collected satellite imagery and analysis breaking process in major ship breaking yards between year 2009 and 2011. Comparing the number of recycling ships by satellite imagery to the world statistics is in good agreement. In this study, Remote Sensing Application has been discussed in order to assess the potential to be used for economic activities such as ship recycling in wide coastal area. It was used to evaluate the performance of ship recycling monitoring by Satellite imagery. Additionally, an approach for recognizing ships by SAR imagery regardless of weather conditions is presented.

  17. Image patch analysis of sunspots and active regions

    Directory of Open Access Journals (Sweden)

    Moon Kevin R.


    Full Text Available Context. Separating active regions that are quiet from potentially eruptive ones is a key issue in Space Weather applications. Traditional classification schemes such as Mount Wilson and McIntosh have been effective in relating an active region large scale magnetic configuration to its ability to produce eruptive events. However, their qualitative nature prevents systematic studies of an active region’s evolution for example. Aims. We introduce a new clustering of active regions that is based on the local geometry observed in Line of Sight magnetogram and continuum images. Methods. We use a reduced-dimension representation of an active region that is obtained by factoring the corresponding data matrix comprised of local image patches. Two factorizations can be compared via the definition of appropriate metrics on the resulting factors. The distances obtained from these metrics are then used to cluster the active regions. Results. We find that these metrics result in natural clusterings of active regions. The clusterings are related to large scale descriptors of an active region such as its size, its local magnetic field distribution, and its complexity as measured by the Mount Wilson classification scheme. We also find that including data focused on the neutral line of an active region can result in an increased correspondence between our clustering results and other active region descriptors such as the Mount Wilson classifications and the R-value. Conclusions. Matrix factorization of image patches is a promising new way of characterizing active regions. We provide some recommendations for which metrics, matrix factorization techniques, and regions of interest to use to study active regions.

  18. Probabilistic Tsunami Hazard Analysis: Multiple Sources and Global Applications (United States)

    Grezio, Anita; Babeyko, Andrey; Baptista, Maria Ana; Behrens, Jörn; Costa, Antonio; Davies, Gareth; Geist, Eric L.; Glimsdal, Sylfest; González, Frank I.; Griffin, Jonathan; Harbitz, Carl B.; LeVeque, Randall J.; Lorito, Stefano; Løvholt, Finn; Omira, Rachid; Mueller, Christof; Paris, Raphaël.; Parsons, Tom; Polet, Jascha; Power, William; Selva, Jacopo; Sørensen, Mathilde B.; Thio, Hong Kie


    Applying probabilistic methods to infrequent but devastating natural events is intrinsically challenging. For tsunami analyses, a suite of geophysical assessments should be in principle evaluated because of the different causes generating tsunamis (earthquakes, landslides, volcanic activity, meteorological events, and asteroid impacts) with varying mean recurrence rates. Probabilistic Tsunami Hazard Analyses (PTHAs) are conducted in different areas of the world at global, regional, and local scales with the aim of understanding tsunami hazard to inform tsunami risk reduction activities. PTHAs enhance knowledge of the potential tsunamigenic threat by estimating the probability of exceeding specific levels of tsunami intensity metrics (e.g., run-up or maximum inundation heights) within a certain period of time (exposure time) at given locations (target sites); these estimates can be summarized in hazard maps or hazard curves. This discussion presents a broad overview of PTHA, including (i) sources and mechanisms of tsunami generation, emphasizing the variety and complexity of the tsunami sources and their generation mechanisms, (ii) developments in modeling the propagation and impact of tsunami waves, and (iii) statistical procedures for tsunami hazard estimates that include the associated epistemic and aleatoric uncertainties. Key elements in understanding the potential tsunami hazard are discussed, in light of the rapid development of PTHA methods during the last decade and the globally distributed applications, including the importance of considering multiple sources, their relative intensities, probabilities of occurrence, and uncertainties in an integrated and consistent probabilistic framework.


    Directory of Open Access Journals (Sweden)

    Ruslan Flerovich Vildanov


    Full Text Available Actualized demand of manufactury company's efficiency from the point of quality charachteristics. Reveal unbreakable connection of man and organisation, on example of the comparative analysis of man's and manufacture company's activities. Studing models of company's and men's activities in order to reveal similarity. In order of their implementation to the economics assumes opportunity of using scientific methods, which use for studying functions, vital activities and behavior of the men.

  20. Application of the Periodic Average System Model in Dam Deformation Analysis

    Directory of Open Access Journals (Sweden)

    Yueqian Shen


    Full Text Available Dams are among the most important hydraulic engineering facilities used for water supply, flood control, and hydroelectric power. Monitoring of dams is crucial since deformation might have occurred. How to obtain the deformation information and then judge the safe conditions is the key and difficult problem in dam deformation monitoring field. This paper proposes the periodic average system model and creates the concept of “settlement activity” based on the dam deformation issue. Long-term deformation monitoring data is carried out in a pumped-storage power station, this model combined with settlement activity is used to make the single point deformation analysis, and then the whole settlement activity profile is drawn by clustering analysis. Considering the cumulative settlement value of every point, the dam deformation trend is analyzed in an intuitive effect way. The analysis mode of combined single point with multipoints is realized. The results show that the key deformation information of the dam can be easily grasped by the application of the periodic average system model combined with the distribution diagram of settlement activity. And, above all, the ideas of this research provide an effective method for dam deformation analysis.

  1. [Applications of elementary mode analysis in biological network and pathway analysis]. (United States)

    Zhao, Quanyu; Yu, Shuiyan; Shi, Jiping


    Elementary mode analysis is the widely applied tool in metabolic pathway analysis. Studies based on elementary mode analysis (EMA) were performed for both metabolic network and signal transduction network. Its analytical objective is from cell to bioreactor, and even ecological system. EMA is available to describe biological behaviors by steady state and dynamic models. Not only microorganism metabolism but also human health could be evaluated by EMA. The algorithms and software for calculating elementary mode (EM) were analyzed. The applications of EMA are reviewed such as special metabolic pathway and robustness of metabolic network, metabolic flux decomposition, metabolic flux analysis at steady state, dynamic model and bioprocess simulation, network structure and regulation, strain design and signal transduction network. Solving combinatorial explosion, exploring the relations between EM and metabolic regulation, and improving the algorithm efficiency of strain design are important issues of EMA in future.

  2. Coherent active methods for applications in room acoustics. (United States)

    Guicking, D; Karcher, K; Rollwage, M


    An adjustment of reverberation time in rooms is often desired, even for low frequencies where passive absorbers fail. Among the active (electroacoustic) systems, incoherent ones permit lengthening of reverberation time only, whereas coherent active methods will allow sound absorption as well. A coherent-active wall lining consists of loudspeakers with microphones in front and adjustable control electronics. The microphones pick up the incident sound and drive the speakers in such a way that the reflection coefficient takes on prescribed values. An experimental device for the one-dimensional case allows reflection coefficients between almost zero and about 1.5 to be realized below 1000 Hz. The extension to three dimensions presents problems, especially by nearfield effects. Experiments with a 3 X 3 loudspeaker array and computer simulations proved that the amplitude reflection coefficient can be adjusted between 10% and 200% for sinusoidal waves at normal and oblique incidence. Future developments have to make the system work with broadband excitation and in more diffuse sound fields. It is also planned to combine the active reverberation control with active diffusion control.

  3. Value of Earth Observations: NASA Activities with Socioeconomic Analysis (United States)

    Friedl, L.


    There is greater emphasis internationally on the social and economic benefits that organizations can derive from applications of Earth observations. A growing set of qualitative, anecdotal examples on the uses of Earth observations across a range of sectors can be complemented by the quantitative substantiation of the socioeconomic benefits. In turn, the expanding breadth of environmental data available and the awareness of their beneficial applications to inform decisions can support new products and services. To support these efforts, there are needs to develop impact assessments, populate the literature, and develop familiarity in the Earth science community with the terms, concepts and methods to assess impacts. Within NASA, the Earth Science Division's Applied Sciences Program has initiated and supported numerous activities in recent years to quantify the socioeconomic benefits from Earth observations applications and to build familiarity within the Earth science community. This paper will present an overview of measuring socioeconomic impacts of Earth observations and how the measures can be translated into a value of Earth observation information. It will address key terms, techniques, principles and applications of socioeconomic impact analyses. It will also discuss activities to support analytic techniques, expand the literature, and promote broader skills and capabilities.

  4. Application of Mathematical Modeling Activities in Costarican High School Education

    Directory of Open Access Journals (Sweden)

    Karen Porras-Lizano


    Full Text Available This paper describes the experience gained in implementing mathematical modeling activities as a methodological strategy in teaching issues such as proportions, with a group of eighth year of an academic-day-school, located in the province of San Jose, Costa Rica in 2012. Different techniques for gathering information were applied, such as participant observation and questionnaires. Among the relevant results are the cyclical development of mathematical thinking of students in the stages of mathematical modeling (description, manipulation, prediction and validation for solving the problem; developing of teamwork skills; and appreciation of mathematics as a useful and effective discipline. To resolve the activities proposed in this study, social interactions such as sharing information, thoughts and ideas, were generated, stimulating the zone of proximal development of the participating students. Likewise, the mathematical modeling activities allowed students to have a positive role in mathematics classes, stimulating, in turn, a different attitude compared to regular classes.

  5. Neutron-activation analysis of natural water applied to hydrogeology

    Energy Technology Data Exchange (ETDEWEB)

    Landstroem, O. [AB Atomenergi, Stockholm (Sweden); Wenner, C.G. [Stockholm Univ. (Sweden). Dept. of Quaternary Research


    The natural content of elements in water has been utilized to characterize different groundwater supplies and reveal the presence of groundwater streams. A neutron-activation method including chemical group separation techniques has been used for the determination of trace elements. Analyzed water samples from three different places in northern Sweden illustrate the application to common and important hydrogeological problems, such as the quality and capacity of water supplies, the origin and existence of groundwater streams and groundwater exchange with rivers.

  6. Neurolinguistic approach to natural language processing with applications to medical text analysis. (United States)

    Duch, Włodzisław; Matykiewicz, Paweł; Pestian, John


    Understanding written or spoken language presumably involves spreading neural activation in the brain. This process may be approximated by spreading activation in semantic networks, providing enhanced representations that involve concepts not found directly in the text. The approximation of this process is of great practical and theoretical interest. Although activations of neural circuits involved in representation of words rapidly change in time snapshots of these activations spreading through associative networks may be captured in a vector model. Concepts of similar type activate larger clusters of neurons, priming areas in the left and right hemisphere. Analysis of recent brain imaging experiments shows the importance of the right hemisphere non-verbal clusterization. Medical ontologies enable development of a large-scale practical algorithm to re-create pathways of spreading neural activations. First concepts of specific semantic type are identified in the text, and then all related concepts of the same type are added to the text, providing expanded representations. To avoid rapid growth of the extended feature space after each step only the most useful features that increase document clusterization are retained. Short hospital discharge summaries are used to illustrate how this process works on a real, very noisy data. Expanded texts show significantly improved clustering and may be classified with much higher accuracy. Although better approximations to the spreading of neural activations may be devised a practical approach presented in this paper helps to discover pathways used by the brain to process specific concepts, and may be used in large-scale applications.

  7. Performance Analysis, Modeling and Scaling of HPC Applications and Tools

    Energy Technology Data Exchange (ETDEWEB)

    Bhatele, Abhinav [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    E cient use of supercomputers at DOE centers is vital for maximizing system throughput, mini- mizing energy costs and enabling science breakthroughs faster. This requires complementary e orts along several directions to optimize the performance of scienti c simulation codes and the under- lying runtimes and software stacks. This in turn requires providing scalable performance analysis tools and modeling techniques that can provide feedback to physicists and computer scientists developing the simulation codes and runtimes respectively. The PAMS project is using time allocations on supercomputers at ALCF, NERSC and OLCF to further the goals described above by performing research along the following fronts: 1. Scaling Study of HPC applications; 2. Evaluation of Programming Models; 3. Hardening of Performance Tools; 4. Performance Modeling of Irregular Codes; and 5. Statistical Analysis of Historical Performance Data. We are a team of computer and computational scientists funded by both DOE/NNSA and DOE/ ASCR programs such as ECRP, XStack (Traleika Glacier, PIPER), ExaOSR (ARGO), SDMAV II (MONA) and PSAAP II (XPACC). This allocation will enable us to study big data issues when analyzing performance on leadership computing class systems and to assist the HPC community in making the most e ective use of these resources.

  8. Informational analysis involving application of complex information system (United States)

    Ciupak, Clébia; Vanti, Adolfo Alberto; Balloni, Antonio José; Espin, Rafael

    The aim of the present research is performing an informal analysis for internal audit involving the application of complex information system based on fuzzy logic. The same has been applied in internal audit involving the integration of the accounting field into the information systems field. The technological advancements can provide improvements to the work performed by the internal audit. Thus we aim to find, in the complex information systems, priorities for the work of internal audit of a high importance Private Institution of Higher Education. The applied method is quali-quantitative, as from the definition of strategic linguistic variables it was possible to transform them into quantitative with the matrix intersection. By means of a case study, where data were collected via interview with the Administrative Pro-Rector, who takes part at the elaboration of the strategic planning of the institution, it was possible to infer analysis concerning points which must be prioritized at the internal audit work. We emphasize that the priorities were identified when processed in a system (of academic use). From the study we can conclude that, starting from these information systems, audit can identify priorities on its work program. Along with plans and strategic objectives of the enterprise, the internal auditor can define operational procedures to work in favor of the attainment of the objectives of the organization.

  9. Radiocarbon analysis of human remains: a review of forensic applications. (United States)

    Ubelaker, Douglas H


    Radiocarbon analysis of organic materials, with the comparison of values with those of the post-1950 modern bomb curve, has proven useful in forensic science to help evaluate the antiquity of evidence. Applications are particularly helpful in the study of human remains, especially with those displaying advanced decomposition of soft tissues. Radiocarbon analysis can reveal if the remains relate to the modern, post-1950 era and if so, also provide information needed to evaluate the death and birth date. Sample selection and interpretation of results must be guided by knowledge of the formation and remodeling of different human tissues, as well as contextual information and the approximate age at death of the individual represented. Dental enamel does not remodel and thus captures dietary radiocarbon values at the time of juvenile formation. Most other human tissues do remodel but at differing rates and therefore collectively offer key information relative to the estimation of the death date. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  10. Antimicrobial Dendrimeric Peptides: Structure, Activity and New Therapeutic Applications. (United States)

    Scorciapino, Mariano A; Serra, Ilaria; Manzo, Giorgia; Rinaldi, Andrea C


    Microbial resistance to conventional antibiotics is one of the most outstanding medical and scientific challenges of our times. Despite the recognised need for new anti-infective agents, however, very few new drugs have been brought to the market and to the clinic in the last three decades. This review highlights the properties of a new class of antibiotics, namely dendrimeric peptides. These intriguing novel compounds, generally made of multiple peptidic sequences linked to an inner branched core, display an array of antibacterial, antiviral and antifungal activities, usually coupled to low haemolytic activity. In addition, several peptides synthesized in oligobranched form proved to be promising tools for the selective treatment of cancer cells.

  11. Biomedical Applications of Thermally Activated Shape Memory Polymers

    Energy Technology Data Exchange (ETDEWEB)

    Small IV, W; Singhal, P; Wilson, T S; Maitland, D J


    Shape memory polymers (SMPs) are smart materials that can remember a primary shape and can return to this primary shape from a deformed secondary shape when given an appropriate stimulus. This property allows them to be delivered in a compact form via minimally invasive surgeries in humans, and deployed to achieve complex final shapes. Here we review the various biomedical applications of SMPs and the challenges they face with respect to actuation and biocompatibility. While shape memory behavior has been demonstrated with heat, light and chemical environment, here we focus our discussion on thermally stimulated SMPs.

  12. Magnetic Testing, and Modeling, Simulation and Analysis for Space Applications (United States)

    Boghosian, Mary; Narvaez, Pablo; Herman, Ray


    The Aerospace Corporation (Aerospace) and Lockheed Martin Space Systems (LMSS) participated with Jet Propulsion Laboratory (JPL) in the implementation of a magnetic cleanliness program of the NASA/JPL JUNO mission. The magnetic cleanliness program was applied from early flight system development up through system level environmental testing. The JUNO magnetic cleanliness program required setting-up a specialized magnetic test facility at Lockheed Martin Space Systems for testing the flight system and a testing program with facility for testing system parts and subsystems at JPL. The magnetic modeling, simulation and analysis capability was set up and performed by Aerospace to provide qualitative and quantitative magnetic assessments of the magnetic parts, components, and subsystems prior to or in lieu of magnetic tests. Because of the sensitive nature of the fields and particles scientific measurements being conducted by the JUNO space mission to Jupiter, the imposition of stringent magnetic control specifications required a magnetic control program to ensure that the spacecraft's science magnetometers and plasma wave search coil were not magnetically contaminated by flight system magnetic interferences. With Aerospace's magnetic modeling, simulation and analysis and JPL's system modeling and testing approach, and LMSS's test support, the project achieved a cost effective approach to achieving a magnetically clean spacecraft. This paper presents lessons learned from the JUNO magnetic testing approach and Aerospace's modeling, simulation and analysis activities used to solve problems such as remnant magnetization, performance of hard and soft magnetic materials within the targeted space system in applied external magnetic fields.

  13. The effect of glyphosate application on soil microbial activities in ...

    African Journals Online (AJOL)

    In this study, glyphosate effects as N, P and C nutrient sources on microbial population and the effect of different concentration of it on dehydrogenease activity and soil respiration were investigated. The results show that in a soil with a long historical use of glyphosate (soil 1), the hetrotrophic bacterial population was ...

  14. Antibacterial activity of essential oils: potential applications in food

    NARCIS (Netherlands)

    Burt, S.A.


    Due to its antibacterial activity, oregano oil has lately become interesting as a potential 'natural' food preservative. Oregano oil was found to be a fast acting and effective inhibitor of a strain of Escherichia coli O157:H7, the causative agent of a serious gastro-enteritis, and was lethal to

  15. Recent Research and Application Activities on Structural Health ...

    African Journals Online (AJOL)

    ... measured data, and (4) a test road project for pavement design verification and enhancement by the Korea Highway Corporation. Finally R&D activities of a new engineering research center entitled Smart Infra-Structure Technology Center at Korea Advanced Institute of Science and Technology are also briefly described.

  16. Application of activated carbon from empty fruit bunch (EFB) for ...

    African Journals Online (AJOL)

    Mercury is a heavy metal and is used widely in the industry, making it a global problem. It accounts for approximately 70% of man-made emissions. Activated carbon was found to be efficient for the adsorption of Hg(ll) in aqueous solution. The characterization of Hg(ll) uptake showed that the mercury binding is dependent ...

  17. Temperature effects on surface activity and application in oxidation ...

    Indian Academy of Sciences (India)

    Correspondingly, the CMC of CTAB-SDS decreases almost by half. The increase of surface activity of CTAB-SDS can be attributed to the relatively weak electrostatic interaction at high temperature, which is supported by the increase of solubility of CTAB-SDS with rise in temperature. Catalytic effect on oxidation of toluene ...

  18. Possible applications of alkali-activated systems in construction

    Czech Academy of Sciences Publication Activity Database

    Boháčová, J.; Staněk, S.; Vavro, Martin


    Roč. 12, č. 2 (2013), s. 8-17 ISSN 1804-4824 Institutional support: RVO:68145535 Keywords : alkali-activated system * geopolymer * binder Subject RIV: JN - Civil Engineering xml ?format=INT

  19. The Didactic Principles and Their Applications in the Didactic Activity (United States)

    Marius-Costel, Esi


    The evaluation and reevaluation of the fundamental didactic principles suppose the acceptance at the level of an instructive-educative activity of a new educational paradigm. Thus, its understanding implies an assumption at a conceptual-theoretical level of some approaches where the didactic aspects find their usefulness by relating to value…

  20. Lithography process calibration with applications in defect printability analysis (United States)

    Wu, Shao-Po; Liu, Hua-Yu; Chang, Fang C.; Karklin, Linard


    Lithography process simulation has proven to be a useful and effective tool for process characterization, namely, properly characterize critical dimension (CD) variations from the design that are caused by proximity effects and distortions introduced by the patterning tool, reticle, resist processing and etching. Accurate lithography process simulator further enables process engineers to automate the tasks of advanced mask design, verification and inspection that are used in deep-sub-micron semiconductor manufacturing. However, to get the most benefit from process simulations, we should properly calibrate the simulation model according to the process to be characterized. That is, given a representative set of CD measurements obtained from the process, we fine-tune the process model parameters so that the simulated/predicted CDs well match the measured CDs. By doing so, we can ensure to some extent that process simulations give sensible results to be used in the design analysis, verification and inspection applications. In this paper, we would like to demonstrate the possibility of obtaining an accurate process model for lithography process simulations via model calibration. We will also demonstrate the accuracy of calibrated process simulations by applying the calibrated model in mask defect printability analysis. For simplicity, the process model and the algorithms used in model calibration will not be discussed in this article but in our future publications. In Section 2, we present the characterization and calibration of a 0.18 micrometer DUV lithography process using positive chemically amplified resist (APEX-E) as an example. We describe the test pattern selections, the calibration process, and the performance of the calibrated model in terms of predicting the CD measurements given test patterns. In Section 3, we briefly describe the technology of defect printability analysis based on process simulations. We will demonstrate that with the help of calibrated