WorldWideScience

Sample records for action model space

  1. Tracking in Object Action Space

    DEFF Research Database (Denmark)

    Krüger, Volker; Herzog, Dennis

    2013-01-01

    In this paper we focus on the joint problem of tracking humans and recognizing human action in scenarios such as a kitchen scenario or a scenario where a robot cooperates with a human, e.g., for a manufacturing task. In these scenarios, the human directly interacts with objects physically by using......-dimensional action space. In our approach, we use parametric hidden Markov models to represent parametric movements; particle filtering is used to track in the space of action parameters. We demonstrate its effectiveness on synthetic and on real image sequences using human-upper body single arm actions that involve...

  2. Learning Actions Models: Qualitative Approach

    DEFF Research Database (Denmark)

    Bolander, Thomas; Gierasimczuk, Nina

    2015-01-01

    identifiability (conclusively inferring the appropriate action model in finite time) and identifiability in the limit (inconclusive convergence to the right action model). We show that deterministic actions are finitely identifiable, while non-deterministic actions require more learning power......—they are identifiable in the limit.We then move on to a particular learning method, which proceeds via restriction of a space of events within a learning-specific action model. This way of learning closely resembles the well-known update method from dynamic epistemic logic. We introduce several different learning...

  3. Space Science in Action: Space Exploration [Videotape].

    Science.gov (United States)

    1999

    In this videotape recording, students learn about the human quest to discover what is out in space. Students see the challenges and benefits of space exploration including the development of rocket science, a look back at the space race, and a history of manned space travel. A special section on the Saturn V rocket gives students insight into the…

  4. Using Continuous Action Spaces to Solve Discrete Problems

    NARCIS (Netherlands)

    van Hasselt, Hado; Wiering, Marco

    2009-01-01

    Real-world control problems are often modeled as Markov Decision Processes (MDPs) with discrete action spaces to facilitate the use of the many reinforcement learning algorithms that exist to find solutions for such MDPs. For many of these problems an underlying continuous action space can be

  5. Affirmative action as organization development at the Johnson Space Center

    Science.gov (United States)

    Tryman, Mfanya Donald L.

    1987-01-01

    The role of affirmative actions is investigated as an interventionist Organization Development (OD) strategy for insuring equal opportunities at the NASA/Johnson Space Center. In doing so, an eclectic and holistic model is developed for the recruiting and hiring of minorities and females over the next five years. The strategy, approach, and assumptions for the model are quite different than those for JSC's five year plan. The study concludes that Organization development utilizing affirmative action is a valid means to bring about organizational change and renewal processes, and that an eclectic model of affirmative action is most suitable and rational in obtaining this end.

  6. Learning Action Models: Qualitative Approach

    NARCIS (Netherlands)

    Bolander, T.; Gierasimczuk, N.; van der Hoek, W.; Holliday, W.H.; Wang, W.-F.

    2015-01-01

    In dynamic epistemic logic, actions are described using action models. In this paper we introduce a framework for studying learnability of action models from observations. We present first results concerning propositional action models. First we check two basic learnability criteria: finite

  7. Sound objects in time, space and action

    OpenAIRE

    Bourquin, N.

    2011-01-01

    SOUND OBJECTS IN TIME, SPACE AND ACTIONThe term "sound object" describes an auditory experience that is associated with an acoustic event produced by a sound source. At cortical level, sound objects are represented by temporo-spatial activity patterns within distributed neural networks. This investigation concerns temporal, spatial and action aspects as assessed in normal subjects using electrical imaging or measurement of motor activity induced by transcranial magnetic stimulation (TMS).Hear...

  8. Space Environment Modeling

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Collection includes presentation materials and outputs from operational space environment models produced by the NOAA Space Weather Prediction Center (SWPC) and...

  9. Active Affordance Learning in Continuous State and Action Spaces

    NARCIS (Netherlands)

    Wang, C.; Hindriks, K.V.; Babuska, R.

    2014-01-01

    Learning object affordances and manipulation skills is essential for developing cognitive service robots. We propose an active affordance learning approach in continuous state and action spaces without manual discretization of states or exploratory motor primitives. During exploration in the action

  10. The Perception-Action Model

    DEFF Research Database (Denmark)

    Grünbaum, Thor

    2017-01-01

    Milner and Goodale’s Two Visual Systems Hypothesis (TVSH) is regarded as common ground in recent discussions of visual consciousness. A central part of TVSH is a functional model of vision and action (a functional perception-action model, PAM for short). In this paper, I provide a brief overview ...... of the role of visual consciousness but also has implications for the role of experimental evidence in model testing in cognitive neuroscience....

  11. Models in Action

    DEFF Research Database (Denmark)

    Juhl, Joakim

    through different material mediations, the thesis draws on the notion of representation as used within science and technology studies to trace how the project translated between the various states of re-presentative mediations. The first four chapters introduce the scope of the study and its wider...... contributed to this development. Because the variation between these practices spanned from work with physical theory to practical hands-on work with machines at operational production sites, the thesis aims to capture how these diverse practices operated and connected by closely following how...... these two opposite processes. By following each stage in both opposite processes, I seek to extend the existing comprehension of models’ technological and epistemological dimensions by describing the different material states the models went through from machine to theory and back again to the machine...

  12. The New Space Weather Action Center; the Next Level on Space Weather Education

    Science.gov (United States)

    Collado-Vega, Y. M.; Lewis, E. M.; Cline, T. D.; MacDonald, E.

    2016-12-01

    The Space Weather Action Center (SWAC) provides access for students to near real-time space weather data, and a set of easy instructions and well-defined protocols that allow them to correctly interpret such data. It is a student centered approach to teaching science and technology in classrooms, as students are encouraged to act like real scientists by accessing, collecting, analyzing, recording, and communicating space weather forecasts. Integration and implementation of several programs will enhance and provide a rich education experience for students' grades 5-16. We will enhance the existing data and tutorials available using the Integrated Space Weather Analysis (iSWA) tool created by the Community Coordinated Modeling Center (CCMC) at NASA GSFC. iSWA is a flexible, turn-key, customer-configurable, Web-based dissemination system for NASA-relevant space weather information that combines data based on the most advanced space weather models available through the CCMC with concurrent space environment information. This tool provides an additional component by the use of videos and still imagery from different sources as a tool for educators to effectively show what happens during an eruption from the surface of the Sun. We will also update content on the net result of space weather forecasting that the public can experience by including Aurorasaurus, a well established, growing, modern, innovative, interdisciplinary citizen science project centered around the public's visibility of the northern lights with mobile applications via the use of social media connections.

  13. Homogeneous spaces and transitive actions by Polish groups

    NARCIS (Netherlands)

    van Mill, J.

    2008-01-01

    We prove that for every homogeneous and strongly locally homogeneous Polish space X there is a Polish group admitting a transitive action on X. We also construct an example of a homogeneous Polish space which is not a coset space and on which no separable metrizable topological group acts

  14. Towards reasoning and coordinating action in the mental space.

    Science.gov (United States)

    Mohan, Vishwanathan; Morasso, Pietro

    2007-08-01

    Unlike a purely reactive system where the motor output is exclusively controlled by the actual sensory input, a cognitive system must be capable of running mental processes which virtually simulate action sequences aimed at achieving a goal. The mental process either attempts to find a feasible course of action compatible with a number of constraints (Internal, Environmental, Task Specific etc) or selects it from a repertoire of previously learned actions, according to the parameters of the task. If neither reasoning process succeeds, a typical backup strategy is to look for a tool that might allow the operator to match all the task constraints. This further necessitates having the capability to alter ones own goal structures to generate sub-goals which must be successfully accomplished in order to achieve the primary goal. In this paper, we introduce a forward/inverse motor control architecture (FMC/IMC) that relaxes an internal model of the overall kinematic chain to a virtual force field applied to the end effector, in the intended direction of movement. This is analogous to the mechanism of coordinating the motion of a wooden marionette by means of attached strings. The relaxation of the FMC/IMC pair provides a general solution for mentally simulating an action of reaching a target position taking into consideration a range of geometric constraints (range of motion in the joint space, internal and external constraints in the workspace) as well as effort-related constraints (range of torque of the actuators, etc.). In case, the forward simulation is successful, the movement is executed; otherwise the residual "error" or measure of inconsistency is taken as a starting point for breaking the action plan into a sequence of sub actions. This process is achieved using a recurrent neural network (RNN) which coordinates the overall reasoning process of framing and issuing goals to the forward inverse models, searching for alternatives tools in solution space and

  15. Space Science in Action: Astronomy [Videotape].

    Science.gov (United States)

    1999

    This videotape recording teaches students about constellations, star movement, and how scientists have studied celestial bodies throughout history from Ptolemy to Copernicus to the work of the Hubble Space Telescope. An interview with Kathy Thornton, one of the astronauts who repaired the Hubble while in orbit, is featured. A hands-on activity…

  16. Collective action and rationality models

    Directory of Open Access Journals (Sweden)

    Luis Miguel Miller Moya

    2004-01-01

    Full Text Available The Olsonian theory of collective action (Olson, 1965 assumes a model of economic rationality, based on a simple calculus between costs and benefits, that can be hardly hold at present, given the models of rationality proposed recently by several fields of research. In relation to these fields, I will concentrate in two specific proposals, namely: evolutionary game theory and, over all, the theory of bounded rationality. Both alternatives are specially fruitful in order to propose models that do not need a maximizing rationality, or environments of complete and perfect information. Their approaches, based on the possibility of individual learning over the time, have contributed to the analysis of the emergence of social norms, which is something really necessary to the resolution of problems related to cooperation. Thus, this article asserts that these two new theoretical contributions make feasible a fundamental advance in the study of collective action.

  17. Application of Conformational Space Search in Drug Action | Adikwu ...

    African Journals Online (AJOL)

    The role of conformational space in drug action is presented. Two examples of molecules in different therapeutic groups are presented. Conformational space search will lead to isolating the exact conformation with the desired medicinal properties. Many conformations of a plant isolate may exist which are active, weakly ...

  18. "Implicit action": Understanding discourse management in modeling instruction

    Science.gov (United States)

    Durden, Jared; Brewe, Eric; Kramer, Laird

    2012-02-01

    We present "Implicit Action", a discourse management tool, through a qualitative video analysis of a Florida International University Modeling Instruction Introductory Physics I class. Implicit Action in Modeling Instruction is where instructors deliberately create intellectual space in which students ideally see value and need for the construction of new classroom norms and tools that are productive in developing a learning community. This space is created by the implications expressed through the instructors' deliberate actions. Discourse Management is a technique to moderate student discourse in Modeling Instruction classes at the university level that was initially described by Desbien [1]. Implicit Action is one of 9 Modeling Discourse Management tools that we have identified. By means of qualitative analysis we illustrate the effectiveness of Implicit Action in implementing the Modeling Theory of Instruction.

  19. Creating communicative spaces in an action research study.

    Science.gov (United States)

    Bevan, Ann L

    2013-11-01

    To argue that creating communicative spaces in an action research study gave voice to young mothers who may otherwise have remained voiceless. Underpinning the concept of the communicative space in action research is the critical social theory of Jürgen Habermas, in particular, his theory of communicative action and the ideal speech situation. The author argues that in collaborative research, the successful creation of a communicative space is vital in enabling equitable and discursive speech to take place. This is a methodological paper. This approach provided a discursive space to participants who ordinarily may not have interacted, and led to the sharing of different perceptions and understandings that may not otherwise have been possible. This research pointed to the possibility of the ideal speech situation, and the value of opening up a communicative space for researchers and participants. Action research for professionals is a sometimes messy and time-consuming process. However, it is a rewarding approach that uncovers layers of interpretations and understanding that have meaning for the participants involved. The creation of communicative spaces has the potential to enrich nursing research because of its participatory nature, making it more likely that solutions reached will have meaning to people.

  20. Unsupervised Action Classification Using Space-Time Link Analysis

    Directory of Open Access Journals (Sweden)

    Feris Rogerio

    2010-01-01

    Full Text Available We address the problem of unsupervised discovery of action classes in video data. Different from all existing methods thus far proposed for this task, we present a space-time link analysis approach which consistently matches or exceeds the performance of traditional unsupervised action categorization methods in various datasets. Our method is inspired by the recent success of link analysis techniques in the image domain. By applying these techniques in the space-time domain, we are able to naturally take into account the spatiotemporal relationships between the video features, while leveraging the power of graph matching for action classification. We present a comprehensive set of experiments demonstrating that our approach is capable of handling cluttered backgrounds, activities with subtle movements, and video data from moving cameras. State-of-the-art results are reported on standard datasets. We also demonstrate our method in a compelling surveillance application with the goal of avoiding fraud in retail stores.

  1. Unsupervised action classification using space-time link analysis

    DEFF Research Database (Denmark)

    Liu, Haowei; Feris, Rogerio; Krüger, Volker

    2010-01-01

    In this paper we address the problem of unsupervised discovery of action classes in video data. Different from all existing methods thus far proposed for this task, we present a space-time link analysis approach which matches the performance of traditional unsupervised action categorization methods...... in a standard dataset. Our method is inspired by the recent success of link analysis techniques in the image domain. By applying these techniques in the space-time domain, we are able to naturally take into account the spatio-temporal relationships between the video features, while leveraging the power of graph...... matching for action classification. We present an experiment to demonstrate that our approach is capable of handling cluttered backgrounds, activities with subtle movements, and video data from moving cameras....

  2. Learning to Act: Qualitative Learning of Deterministic Action Models

    DEFF Research Database (Denmark)

    Bolander, Thomas; Gierasimczuk, Nina

    2017-01-01

    in the limit (inconclusive convergence to the right action model). We show that deterministic actions are finitely identifiable, while arbitrary (non-deterministic) actions require more learning power—they are identifiable in the limit. We then move on to a particular learning method, i.e. learning via update......, which proceeds via restriction of a space of events within a learning-specific action model. We show how this method can be adapted to learn conditional and unconditional deterministic action models. We propose update learning mechanisms for the afore mentioned classes of actions and analyse...... their computational complexity. Finally, we study a parametrized learning method which makes use of the upper bound on the number of propositions relevant for a given learning scenario. We conclude with describing related work and numerous directions of further work....

  3. Response actions influence the categorization of directions in auditory space

    Directory of Open Access Journals (Sweden)

    Marcella de Castro Campos Velten

    2015-08-01

    Full Text Available Spatial region concepts such as front, back, left and right reflect our typical interaction with space, and the corresponding surrounding regions have different statuses in memory. We examined the representation of spatial directions in the auditory space, specifically in how far natural response actions, such as orientation movements towards a sound source, would affect the categorization of egocentric auditory space. While standing in the middle of a circle with 16 loudspeakers, participants were presented acoustic stimuli coming from the loudspeakers in randomized order, and verbally described their directions by using the concept labels front, back, left, right, front-right, front-left, back-right and back-left. Response actions varied in three blocked conditions: 1 facing front, 2 turning the head and upper body to face the stimulus, and 3 turning the head and upper body plus pointing with the hand and outstretched arm towards the stimulus. In addition to a protocol of the verbal utterances, motion capture and video recording generated a detailed corpus for subsequent analysis of the participants’ behavior. Chi-square tests revealed an effect of response condition for directions within the left and right sides. We conclude that movement-based response actions influence the representation of auditory space, especially within the sides’ regions.

  4. Functional differentiation of macaque visual temporal cortical neurons using a parametric action space.

    Science.gov (United States)

    Vangeneugden, Joris; Pollick, Frank; Vogels, Rufin

    2009-03-01

    Neurons in the rostral superior temporal sulcus (STS) are responsive to displays of body movements. We employed a parametric action space to determine how similarities among actions are represented by visual temporal neurons and how form and motion information contributes to their responses. The stimulus space consisted of a stick-plus-point-light figure performing arm actions and their blends. Multidimensional scaling showed that the responses of temporal neurons represented the ordinal similarity between these actions. Further tests distinguished neurons responding equally strongly to static presentations and to actions ("snapshot" neurons), from those responding much less strongly to static presentations, but responding well when motion was present ("motion" neurons). The "motion" neurons were predominantly found in the upper bank/fundus of the STS, and "snapshot" neurons in the lower bank of the STS and inferior temporal convexity. Most "motion" neurons showed strong response modulation during the course of an action, thus responding to action kinematics. "Motion" neurons displayed a greater average selectivity for these simple arm actions than did "snapshot" neurons. We suggest that the "motion" neurons code for visual kinematics, whereas the "snapshot" neurons code for form/posture, and that both can contribute to action recognition, in agreement with computation models of action recognition.

  5. Conformal higher spin theory and twistor space actions

    Science.gov (United States)

    Hähnel, Philipp; McLoughlin, Tristan

    2017-12-01

    We consider the twistor description of conformal higher spin theories and give twistor space actions for the self-dual sector of theories with spin greater than two that produce the correct flat space-time spectrum. We identify a ghost-free subsector, analogous to the embedding of Einstein gravity with cosmological constant in Weyl gravity, which generates the unique spin-s three-point anti-MHV amplitude consistent with Poincaré invariance and helicity constraints. By including interactions between the infinite tower of higher-spin fields we give a geometric interpretation to the twistor equations of motion as the integrability condition for a holomorphic structure on an infinite jet bundle. Finally, we conjecture anti-self-dual interaction terms which give an implicit definition of a twistor action for the full conformal higher spin theory.

  6. The power of teams that disagree:team formation in large action spaces

    OpenAIRE

    Soriano Marcolino, Leandro; Xu,Haifeng; Xin Jiang, Albert; Tambe, Milind; Bowring, Emma

    2015-01-01

    Recent work has shown that diverse teams can outperform a uniform team made of copies of the best agent. However, there are fundamental questions that were never asked before. When should we use diverse or uniform teams? How does the performance change as the action space or the teams get larger? Hence, we present a new model of diversity, where we prove that the performance of a diverse team improves as the size of the action space increases. Moreover, we show that the performance converges ...

  7. Representing the Meanings of Object and Action Words: The Featural and Unitary Semantic Space Hypothesis

    Science.gov (United States)

    Vigliocco, Gabriella; Vinson, David P.; Lewis, William; Garrett, Merrill F.

    2004-01-01

    This paper presents the Featural and Unitary Semantic Space (FUSS) hypothesis of the meanings of object and action words. The hypothesis, implemented in a statistical model, is based on the following assumptions: First, it is assumed that the meanings of words are grounded in conceptual featural representations, some of which are organized…

  8. Action Research as a Space for Transforming Learning Cultures

    Directory of Open Access Journals (Sweden)

    Elżbieta Wołodźko

    2015-12-01

    Full Text Available The article presents a three-year educational action research project on autonomous and reflective learning. Students and teachers, being actively engaged in many learning practices, were both participating in process(es of developing educational and research community. These interrelated processes framed a dynamic space for constructing and reconstructing the participants’ learning cultures. Thanks to linking educational and research aspects of students’ activity and to interpenetration of practice and reflection, action research generates particular conditions for learning cultures’ transformation, from “traditional” toward “new” ones, based on reflectivity, authenticity and empowerment. The dynamism of learning cultures was connected to various and conscious and reflective types of educational participation, which affected autonomy of studying (in its numerous dimensions and types, being in turn a constitutive element of participants’ learning cultures.

  9. State Space Modeling Using SAS

    Directory of Open Access Journals (Sweden)

    Rajesh Selukar

    2011-05-01

    Full Text Available This article provides a brief introduction to the state space modeling capabilities in SAS, a well-known statistical software system. SAS provides state space modeling in a few different settings. SAS/ETS, the econometric and time series analysis module of the SAS system, contains many procedures that use state space models to analyze univariate and multivariate time series data. In addition, SAS/IML, an interactive matrix language in the SAS system, provides Kalman filtering and smoothing routines for stationary and nonstationary state space models. SAS/IML also provides support for linear algebra and nonlinear function optimization, which makes it a convenient environment for general-purpose state space modeling.

  10. Simplicial models for trace spaces

    DEFF Research Database (Denmark)

    Raussen, Martin

    , we outline a generalization to model spaces known as Higher Dimensional Automata. In particular, we describe algorithms that allow to determine not only the fundamental category of such amodel space, but all homological invariants of spaces of directed paths within it. The prodsimplical complexes...... motivation stems from certain models for concurrent computation. So far, spaces of d-paths and their topological invariants have only been determined in cases that were elementary to overlook. In this paper, we develop a systematic approach describing spaces of directed paths - up to homotopy equivalence...... - as prodsimplicial complexes (with products of simplices as building blocks). This method makes use of certain poset categories of binary matrices and applies to a class of directed spaces that arise from a class of models of computation; still restricted but with a fair amount of generality. In the final section...

  11. A neural network model of causative actions.

    Science.gov (United States)

    Lee-Hand, Jeremy; Knott, Alistair

    2015-01-01

    A common idea in models of action representation is that actions are represented in terms of their perceptual effects (see e.g., Prinz, 1997; Hommel et al., 2001; Sahin et al., 2007; Umiltà et al., 2008; Hommel, 2013). In this paper we extend existing models of effect-based action representations to account for a novel distinction. Some actions bring about effects that are independent events in their own right: for instance, if John smashes a cup, he brings about the event of the cup smashing. Other actions do not bring about such effects. For instance, if John grabs a cup, this action does not cause the cup to "do" anything: a grab action has well-defined perceptual effects, but these are not registered by the perceptual system that detects independent events involving external objects in the world. In our model, effect-based actions are implemented in several distinct neural circuits, which are organized into a hierarchy based on the complexity of their associated perceptual effects. The circuit at the top of this hierarchy is responsible for actions that bring about independently perceivable events. This circuit receives input from the perceptual module that recognizes arbitrary events taking place in the world, and learns movements that reliably cause such events. We assess our model against existing experimental observations about effect-based motor representations, and make some novel experimental predictions. We also consider the possibility that the "causative actions" circuit in our model can be identified with a motor pathway reported in other work, specializing in "functional" actions on manipulable tools (Bub et al., 2008; Binkofski and Buxbaum, 2013).

  12. Awareness, Solidarity, and Action: An Educational Model

    Science.gov (United States)

    Reichenbach, Michael R.

    2016-01-01

    How Extension fosters social change and innovation can be improved through the use of theory-based educational models. Educational models can serve as foundations for the conceptual designs of educational interventions. I describe, using examples from my own work, one such model: the awareness, solidarity, and action model. This three-part model…

  13. Model space of economic events

    Science.gov (United States)

    Romanovsky, M. Yu.

    A method for constructing the model or virtual space of economic events when economic objects can be considered as material ones is suggested. We describe change of share rates in time at stock markets as the potential difference of attracted bodies in time in this virtual space. Each share of each enterprise is displayed by a single particle with a unit “charge”. It is shown that the random value of potential difference at the origin of coordinates measured at a definite time interval has the probability density coinciding with the known distribution of “Levy flights” or “Levy walks”. A distribution of alteration in time of the “Standard and Poor” index value obtained by Mantegna and Stanley (they shown that it is the “Levy walks” distribution too) (Mantegna and Stanley, Nature 376 (1995) 46) is used for determination of the introduced potential dependence on coordinates in the model space. A simple phenomenological model of interaction potential is introduced. The potential law of each particle turns out to be closed to r-2.14 in the minimum possible three-dimensional model space. This model permits calculation of time of random potential correlations at a certain point of the model space. These correlations could characterize the time period of making a decision by an investor at stock exchange. It is shown that this time is notably shorter in unstable periods (1987). A “microscopical” model of interaction in the virtual space is also discussed.

  14. Simplicial models of trace spaces

    DEFF Research Database (Denmark)

    Raussen, Martin

    2010-01-01

    Directed algebraic topology studies topological spaces in which certain directed paths (d-paths) are singled out; in most cases of interest, the reverse path of a d-path is no longer a d-path. We are mainly concerned with spaces of directed paths between given end points, and how those vary under...... category of such a model space, but all homological invariants of spaces of directed paths within it. The prodsimplical complexes and their associated chain complexes are finite, but they will, in general, have a huge number of cells and generators....... variation of the end points. The original motivation stems from certain models for concurrent computation. So far, homotopy types of spaces of d-paths and their topological invariants have only been determined in cases that were elementary to overlook. In this paper, we develop a systematic approach...... describing spaces of directed paths – up to homotopy equivalence – as finite prodsimplicial complexes, ie with products of simplices as building blocks. This method makes use of a certain poset category of binary matrices related to a given model space. It applies to a class of directed spaces that arise...

  15. Disentangling Action from Social Space: Tool-Use Differently Shapes the Space around Us.

    Science.gov (United States)

    Patané, Ivan; Iachini, Tina; Farnè, Alessandro; Frassinetti, Francesca

    2016-01-01

    Converging evidence suggests close relationships between the action and social space representations. The concepts of peripersonal space, as defined by cognitive neuroscience, and interpersonal space, as defined by social psychology, refer to approximately the same spatial area surrounding our bodies. The aim of this study was thus to assess experimentally whether the peripersonal (PPS) and interpersonal space (IPS) represent a similar psychological entity. Were this true, they should share some functional features. Here we tested tool-use dependent plasticity, known to modulate PPS, but still unexplored in the IPS. Results from two experiments converge in showing that tool-use remapped the action-related PPS, measured by a Reaching-distance toward a confederate, but did not affect the social-related IPS, measured by a Comfort-distance task. These findings indicate that PPS and IPS rely on dissociable plastic mechanisms and suggest that, at least in the present experimental conditions, there is no full functional overlap between these two spatial representations.

  16. Computational Modeling of Space Physiology

    Science.gov (United States)

    Lewandowski, Beth E.; Griffin, Devon W.

    2016-01-01

    The Digital Astronaut Project (DAP), within NASAs Human Research Program, develops and implements computational modeling for use in the mitigation of human health and performance risks associated with long duration spaceflight. Over the past decade, DAP developed models to provide insights into space flight related changes to the central nervous system, cardiovascular system and the musculoskeletal system. Examples of the models and their applications include biomechanical models applied to advanced exercise device development, bone fracture risk quantification for mission planning, accident investigation, bone health standards development, and occupant protection. The International Space Station (ISS), in its role as a testing ground for long duration spaceflight, has been an important platform for obtaining human spaceflight data. DAP has used preflight, in-flight and post-flight data from short and long duration astronauts for computational model development and validation. Examples include preflight and post-flight bone mineral density data, muscle cross-sectional area, and muscle strength measurements. Results from computational modeling supplement space physiology research by informing experimental design. Using these computational models, DAP personnel can easily identify both important factors associated with a phenomenon and areas where data are lacking. This presentation will provide examples of DAP computational models, the data used in model development and validation, and applications of the model.

  17. Action Research to Improve the Learning Space for Diagnostic Techniques

    Directory of Open Access Journals (Sweden)

    Ellen Ariel

    2015-08-01

    Full Text Available The module described and evaluated here was created in response to perceived learning difficulties in diagnostic test design and interpretation for students in third-year Clinical Microbiology. Previously, the activities in lectures and laboratory classes in the module fell into the lower cognitive operations of “knowledge” and “understanding.” The new approach was to exchange part of the traditional activities with elements of interactive learning, where students had the opportunity to engage in deep learning using a variety of learning styles. The effectiveness of the new curriculum was assessed by means of on-course student assessment throughout the module, a final exam, an anonymous questionnaire on student evaluation of the different activities and a focus group of volunteers. Although the new curriculum enabled a major part of the student cohort to achieve higher pass grades (p < 0.001, it did not meet the requirements of the weaker students, and the proportion of the students failing the module remained at 34%. The action research applied here provided a number of valuable suggestions from students on how to improve future curricula from their perspective. Most importantly, an interactive online program that facilitated flexibility in the learning space for the different reagents and their interaction in diagnostic tests was proposed. The methods applied to improve and assess a curriculum refresh by involving students as partners in the process, as well as the outcomes, are discussed.

  18. Spectral action models of gravity on packed swiss cheese cosmology

    Science.gov (United States)

    Ball, Adam; Marcolli, Matilde

    2016-06-01

    We present a model of (modified) gravity on spacetimes with fractal structure based on packing of spheres, which are (Euclidean) variants of the packed swiss cheese cosmology models. As the action functional for gravity we consider the spectral action of noncommutative geometry, and we compute its expansion on a space obtained as an Apollonian packing of three-dimensional spheres inside a four-dimensional ball. Using information from the zeta function of the Dirac operator of the spectral triple, we compute the leading terms in the asymptotic expansion of the spectral action. They consist of a zeta regularization of the divergent sum of the leading terms of the spectral actions of the individual spheres in the packing. This accounts for the contribution of points 1 and 3 in the dimension spectrum (as in the case of a 3-sphere). There is an additional term coming from the residue at the additional point in the real dimension spectrum that corresponds to the packing constant, as well as a series of fluctuations coming from log-periodic oscillations, created by the points of the dimension spectrum that are off the real line. These terms detect the fractality of the residue set of the sphere packing. We show that the presence of fractality influences the shape of the slow-roll potential for inflation, obtained from the spectral action. We also discuss the effect of truncating the fractal structure at a certain scale related to the energy scale in the spectral action.

  19. Atomic Action Refinement in Model Based Testing

    NARCIS (Netherlands)

    van der Bijl, H.M.; Rensink, Arend; Tretmans, G.J.

    2007-01-01

    In model based testing (MBT) test cases are derived from a specification of the system that we want to test. In general the specification is more abstract than the implementation. This may result in 1) test cases that are not executable, because their actions are too abstract (the implementation

  20. Space Debris Modeling at NASA

    Science.gov (United States)

    Johnson, Nicholas L.

    2001-01-01

    Since the Second European Conference on Space Debris in 1997, the Orbital Debris Program Office at the NASA Johnson Space Center has undertaken a major effort to update and improve the principal software tools employed to model the space debris environment and to evaluate mission risks. NASA's orbital debris engineering model, ORDEM, represents the current and near-term Earth orbital debris population from the largest spacecraft to the smallest debris in a manner which permits spacecraft engineers and experimenters to estimate the frequency and velocity with which a satellite may be struck by debris of different sizes. Using expanded databases and a new program design, ORDEM2000 provides a more accurate environment definition combined with a much broader array of output products in comparison with its predecessor, ORDEM96. Studies of the potential long-term space debris environment are now conducted with EVOLVE 4.0, which incorporates significant advances in debris characterization and breakup modeling. An adjunct to EVOLVE 4.0, GEO EVOLVE has been created to examine debris issues near the geosynchronous orbital regime. In support of NASA Safety Standard 1740.14, which establishes debris mitigation guidelines for all NASA space programs, a set of evaluation tools called the Debris Assessment Software (DAS) is specifically designed for program offices to determine whether they are in compliance with NASA debris mitigation guidelines. DAS 1.5 has recently been released with improved WINDOWS compatibility and graphics functions. DAS 2.0 will incorporate guideline changes in a forthcoming revision to NASA Safety Standard 1740.14. Whereas DAS contains a simplified model to calculate possible risks associated with satellite reentries, NASA's higher fidelity Object Reentry Survival Analysis Tool (ORSAT) has been upgraded to Version 5.0. With the growing awareness of the potential risks posed by uncontrolled satellite reentries to people and property on Earth, the

  1. Developing Space Weather products and services in Europe – Preface to the Special Issue on COST Action ES0803

    Directory of Open Access Journals (Sweden)

    Belehaki Anna

    2014-01-01

    Full Text Available COST Action ES0803 “Developing Space Weather products and services in Europe” primarily aimed at forming an interdisciplinary network among European scientists dealing with different issues relevant to Geospace as well as warning system developers and operators in order to assess existing Space Weather products and recommend new ones. The work that has been implemented from 2008 to 2012 resulted in advances in modeling and predicting Space Weather, in recommendations for the validation of Space Weather models, in proposals for new Space Weather products and services, and in dissemination, training, and outreach activities. This preface summarizes the most important achievements of this European activity that are detailed in this special issue by the key scientists who participated in COST Action ES0803.

  2. The effects of optical illusions in perception and action in peripersonal and extrapersonal space

    NARCIS (Netherlands)

    Shim, J.; van der Kamp, J

    While the two visual system hypothesis tells a fairly compelling story about perception and action in peripersonal space (i.e., within arm's reach), its validity for extrapersonal space is very limited and highly controversial. Hence, the present purpose was to assess whether perception and action

  3. Free space in the processes of action research

    DEFF Research Database (Denmark)

    Bladt, Mette; Nielsen, Kurt Aagaard

    2013-01-01

    In Scandinavia there exists an action research tradition called critical utopian action research (CUAR). Within CUAR, criticism and utopia is a core activity in the methods used and in the research as such. The utopian concept in this tradition should be understood as a productive concept, and thus...

  4. Embedding a State Space Model Into a Markov Decision Process

    DEFF Research Database (Denmark)

    Nielsen, Lars Relund; Jørgensen, Erik; Højsgaard, Søren

    2011-01-01

    In agriculture Markov decision processes (MDPs) with finite state and action space are often used to model sequential decision making over time. For instance, states in the process represent possible levels of traits of the animal and transition probabilities are based on biological models...

  5. On the existence of star products on quotient spaces of linear Hamiltonian torus actions

    DEFF Research Database (Denmark)

    Herbig, Hans-Christian; Iyengar, Srikanth B.; Pflaum, Markus J.

    2009-01-01

    that the Koszul complex on the moment map of an effective linear Hamiltonian torus action is acyclic. We rephrase the nonpositivity condition of Arms and Gotay (Adv Math 79(1):43–103, 1990) for linear Hamiltonian torus actions. It follows that reduced spaces of such actions admit continuous star products....

  6. SpaceNet: Modeling and Simulating Space Logistics

    Science.gov (United States)

    Lee, Gene; Jordan, Elizabeth; Shishko, Robert; de Weck, Olivier; Armar, Nii; Siddiqi, Afreen

    2008-01-01

    This paper summarizes the current state of the art in interplanetary supply chain modeling and discusses SpaceNet as one particular method and tool to address space logistics modeling and simulation challenges. Fundamental upgrades to the interplanetary supply chain framework such as process groups, nested elements, and cargo sharing, enabled SpaceNet to model an integrated set of missions as a campaign. The capabilities and uses of SpaceNet are demonstrated by a step-by-step modeling and simulation of a lunar campaign.

  7. Preclinical models of antipsychotic drug action

    Science.gov (United States)

    Moreno, José L.; González-Maeso, Javier

    2016-01-01

    One of the main obstacles faced by translational neuroscience is the development of animal models of psychiatric disorders. Behavioural pharmacology studies indicate that psychedelic drugs, such as lysergic acid diethylamide (LSD) and dissociative drugs, such as phencyclidine (PCP), induce in healthy human volunteers psychotic and cognitive symptoms that resemble some of those observed in schizophrenia patients. Serotonin 5-HT2A and metabotropic glutamate 2 receptors have been involved in the mechanism of action of psychedelic and dissociative drugs. Here we review recent advances using LSD-like and PCP-like drugs in rodent models that implicate these receptors in the neurobiology of schizophrenia and its treatment. PMID:23745738

  8. Modeling volatility using state space models.

    Science.gov (United States)

    Timmer, J; Weigend, A S

    1997-08-01

    In time series problems, noise can be divided into two categories: dynamic noise which drives the process, and observational noise which is added in the measurement process, but does not influence future values of the system. In this framework, we show that empirical volatilities (the squared relative returns of prices) exhibit a significant amount of observational noise. To model and predict their time evolution adequately, we estimate state space models that explicitly include observational noise. We obtain relaxation times for shocks in the logarithm of volatility ranging from three weeks (for foreign exchange) to three to five months (for stock indices). In most cases, a two-dimensional hidden state is required to yield residuals that are consistent with white noise. We compare these results with ordinary autoregressive models (without a hidden state) and find that autoregressive models underestimate the relaxation times by about two orders of magnitude since they do not distinguish between observational and dynamic noise. This new interpretation of the dynamics of volatility in terms of relaxators in a state space model carries over to stochastic volatility models and to GARCH models, and is useful for several problems in finance, including risk management and the pricing of derivative securities. Data sets used: Olsen & Associates high frequency DEM/USD foreign exchange rates (8 years). Nikkei 225 index (40 years). Dow Jones Industrial Average (25 years).

  9. Initial proposition of kinematics model for selected karate actions analysis

    Science.gov (United States)

    Hachaj, Tomasz; Koptyra, Katarzyna; Ogiela, Marek R.

    2017-03-01

    The motivation for this paper is to initially propose and evaluate two new kinematics models that were developed to describe motion capture (MoCap) data of karate techniques. We decided to develop this novel proposition to create the model that is capable to handle actions description both from multimedia and professional MoCap hardware. For the evaluation purpose we have used 25-joints data with karate techniques recordings acquired with Kinect version 2. It is consisted of MoCap recordings of two professional sport (black belt) instructors and masters of Oyama Karate. We have selected following actions for initial analysis: left-handed furi-uchi punch, right leg hiza-geri kick, right leg yoko-geri kick and left-handed jodan-uke block. Basing on evaluation we made we can conclude that both proposed kinematics models seems to be convenient method for karate actions description. From two proposed variables models it seems that global might be more useful for further usage. We think that because in case of considered punches variables seems to be less correlated and they might also be easier to interpret because of single reference coordinate system. Also principal components analysis proved to be reliable way to examine the quality of kinematics models and with the plot of the variable in principal components space we can nicely present the dependences between variables.

  10. Animal models for aberrations of gonadotropin action.

    Science.gov (United States)

    Peltoketo, Hellevi; Zhang, Fu-Ping; Rulli, Susana B

    2011-12-01

    During the last two decades a large number of genetically modified mouse lines with altered gonadotropin action have been generated. These mouse lines fall into three categories: the lack-of-function mice, gain-of-function mice, and the mice generated by breeding the abovementioned lines with other disease model lines. The mouse strains lacking gonadotropin action have elucidated the necessity of the pituitary hormones in pubertal development and function of gonads, and revealed the processes from the original genetic defect to the pathological phenotype such as hypo- or hypergonadotropic hypogonadism. Conversely, the strains of the second group depict consequences of chronic gonadotropin action. The lines vary from those expressing constitutively active receptors and those secreting follicle-stimulating hormone (FSH) with slowly increasing amounts to those producing human choriogonadotropin (hCG), amount of which corresponds to 2000-fold luteinizing hormone (LH)/hCG biological activity. Accordingly, the phenotypes diverge from mild anomalies and enhanced fertility to disrupted gametogenesis, but eventually chronic, enhanced and non-pulsatile action of both FSH and LH leads to female and male infertility and/or hyper- and neoplasias in most of the gonadotropin gain-of-function mice. Elevated gonadotropin levels also alter the function of several extra-gonadal tissues either directly or indirectly via increased sex steroid production. These effects include promotion of tumorigenesis in tissues such as the pituitary, mammary and adrenal glands. Finally, the crossbreedings of the current mouse strains with other disease models are likely to uncover the contribution of gonadotropins in novel biological systems, as exemplified by the recent crossbreed of LHCG receptor deficient mice with Alzheimer disease mice.

  11. Pro-torus actions on Poincaré duality spaces

    Indian Academy of Sciences (India)

    duality spaces, Borel's dimension formula and topological splitting principle to local weights, hold if 'torus' is replaced by 'pro-torus'. Keywords. Pro-torus; Poincaré duality space; local weight. 1. Introduction. In the theory of linear representations of compact connected Lie groups, the crucial first step is restriction to the ...

  12. Spectral Action Models of Gravity on Packed Swiss Cheese Cosmology

    CERN Document Server

    Ball, Adam

    2015-01-01

    We present a model of (modified) gravity on spacetimes with fractal structure based on packing of spheres, which are (Euclidean) variants of the Packed Swiss Cheese Cosmology models. As the action functional for gravity we consider the spectral action of noncommutative geometry, and we compute its asymptotic expansion on a space obtained as an Apollonian packing of 3-dimensional spheres inside a 4-dimensional ball. Using information from the zeta function of the Dirac operator of the spectral triple, we show that the leading terms in the asymptotic expansion of the spectral action consist of a zeta regularization of the divergent sum of the leading terms of the spectral actions of the individual spheres in the packing, which accounts for the contribution of the points 1 and 3 in the dimension spectrum (as in the case of a 3-sphere). There is also an additional term coming from the residue at the additional point in the dimension spectrum that corresponds to the packing constant. It detects the fractality of t...

  13. Sculpting the space of actions: explaining human action by integrating intentions and mechanisms

    NARCIS (Netherlands)

    Keestra, M.

    2014-01-01

    How can we explain the intentional nature of an expert’s actions, performed without immediate and conscious control, relying instead on automatic cognitive processes? How can we account for the differences and similarities with a novice’s performance of the same actions? Can a naturalist explanation

  14. Faithful actions of locally compact quantum groups on classical spaces

    Science.gov (United States)

    Goswami, Debashish; Roy, Sutanu

    2017-07-01

    We construct examples of locally compact quantum groups coming from bicrossed product construction, including non-Kac ones, which can faithfully and ergodically act on connected classical (noncompact) smooth manifolds. However, none of these actions can be isometric in the sense of Goswami (Commun Math Phys 285(1):141-160, 2009), leading to the conjecture that the result obtained by Goswami and Joardar (Rigidity of action of compact quantum groups on compact, connected manifolds, 2013. arXiv:1309.1294) about nonexistence of genuine quantum isometry of classical compact connected Riemannian manifolds may hold in the noncompact case as well.

  15. Critical Action Learning--Rituals and Reflective Spaces

    Science.gov (United States)

    Heneberry, Pamela; Turner, Arthur

    2016-01-01

    This paper is written to outline our ideas on rituals and reflective places and how this thinking has emerged through our writing, facilitation and reflections around critical action learning and critical leadership. We attempt to show the conceptual framework that underpins our vision of Critical Leadership and how out of this work we have begun…

  16. Effective action for a quantum scalar field in warped spaces

    Energy Technology Data Exchange (ETDEWEB)

    Hoff da Silva, J.M.; Mendonca, E.L.; Scatena, E. [Universidade Estadual Paulista ' ' Julio de Mesquita Filho' ' -UNESP, Departamento de Fisica e Quimica, Guaratingueta, SP (Brazil)

    2015-11-15

    We investigate the one-loop corrections, at zero as well as finite temperature, of a scalar field taking place in a braneworld motivated warped background. After to reach a well-defined problem, we calculate the effective action with the corresponding quantum corrections to each case. (orig.)

  17. Modeling spaces for toleranced objects

    Energy Technology Data Exchange (ETDEWEB)

    Boyer, M.; Stewart, N.F. (Univ. of Montreal, Quebec (Canada))

    1991-10-01

    In this article the authors propose a modeling space for objects defined in terms of tolerances based on Requicha's suggestion of using variational classes. Variational classes are subsets of the hyperspace 2{sup En}, where E{sup n} is euclidean n-space. In order to motivate the ideas, the discussion involves the same simple example throughout: the specification of a ball bearing defined by position, size, and form constraints. They begin by discussing the relationship between Requicha's original proposal and their proposal for a definition of what should be viewed as a permissible variational class. They call such a permissible class, together with a nominal solid S, an R-class. They then introduce generalized versions of the regularized Boolean operations, which operate not on r-sets, but rather on R-classes. Just as the r-sets are closed under regularized Boolean operations, so the R-classes are closed under the generalized versions of the regularized Boolean operations. Finally, they discuss the relationship between the R-classes and the particular feature tolerancing methods proposed by Requicha.

  18. Action potential initiation in the hodgkin-huxley model.

    Directory of Open Access Journals (Sweden)

    Lucy J Colwell

    2009-01-01

    Full Text Available A recent paper of B. Naundorf et al. described an intriguing negative correlation between variability of the onset potential at which an action potential occurs (the onset span and the rapidity of action potential initiation (the onset rapidity. This correlation was demonstrated in numerical simulations of the Hodgkin-Huxley model. Due to this antagonism, it is argued that Hodgkin-Huxley-type models are unable to explain action potential initiation observed in cortical neurons in vivo or in vitro. Here we apply a method from theoretical physics to derive an analytical characterization of this problem. We analytically compute the probability distribution of onset potentials and analytically derive the inverse relationship between onset span and onset rapidity. We find that the relationship between onset span and onset rapidity depends on the level of synaptic background activity. Hence we are able to elucidate the regions of parameter space for which the Hodgkin-Huxley model is able to accurately describe the behavior of this system.

  19. The Effects of Optical Illusions in Perception and Action in Peripersonal and Extrapersonal Space.

    Science.gov (United States)

    Shim, Jaeho; van der Kamp, John

    2017-09-01

    While the two visual system hypothesis tells a fairly compelling story about perception and action in peripersonal space (i.e., within arm's reach), its validity for extrapersonal space is very limited and highly controversial. Hence, the present purpose was to assess whether perception and action differences in peripersonal space hold in extrapersonal space and are modulated by the same factors. To this end, the effects of an optic illusion in perception and action in both peripersonal and extrapersonal space were compared in three groups that threw balls toward a target at a distance under different target eccentricity (i.e., with the target fixated and in peripheral field), viewing (i.e., binocular and monocular viewing), and delay conditions (i.e., immediate and delayed action). The illusory bias was smaller in action than in perception in peripersonal space, but this difference was significantly reduced in extrapersonal space, primarily because of a weakening bias in perception. No systematic modulation of target eccentricity, viewing, and delay arose. The findings suggest that the two visual system hypothesis is also valid for extra personal space.

  20. Extended Hamiltonian action for arbitrary spin fields in flat and AdS space

    Science.gov (United States)

    Metsaev, R. R.

    2013-05-01

    Totally symmetric, arbitrary spin massless and massive free fields in flat and AdS space and conformal fields in flat space are studied. An extended gauge-invariant Hamiltonian action for such fields is obtained. The action is constructed out of phase space fields and Lagrangian multipliers which are free of algebraic constraints. Gauge transformations of the phase space fields and Lagrangian multipliers are derived. Use of the Poincaré parametrization of AdS space allows us to treat fields in flat space and AdS space on an equal footing. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Higher spin theories and holography’.

  1. Lagrangian formulation of symmetric space sine-Gordon models

    CERN Document Server

    Bakas, Ioannis; Shin, H J; Park, Q Han

    1996-01-01

    The symmetric space sine-Gordon models arise by conformal reduction of ordinary 2-dim \\sigma-models, and they are integrable exhibiting a black-hole type metric in target space. We provide a Lagrangian formulation of these systems by considering a triplet of Lie groups F \\supset G \\supset H. We show that for every symmetric space F/G, the generalized sine-Gordon models can be derived from the G/H WZW action, plus a potential term that is algebraically specified. Thus, the symmetric space sine-Gordon models describe certain integrable perturbations of coset conformal field theories at the classical level. We also briefly discuss their vacuum structure, Backlund transformations, and soliton solutions.

  2. Is the ISO Reference Terminology Model for Nursing Actions Enough to Describe Nursing Actions?

    Science.gov (United States)

    Lee, Joo Yun; Park, Hyeoun-Ae

    2016-01-01

    The aim of this study is to test the applicability of the International Standards Organization (ISO) Reference terminology model (RTM) for nursing action to describe Detailed Clinical Models (DCMs) for nursing action. All verb and target terms were mapped to 'Action' and 'Target' category of RTM for nursing actions. Among 72 attributes qualifying the verb terms, 50 attributes were mapped to Means, Route, Timing, or Site categories of the nursing action model. Among 142 attributes qualifying the target terms, 20 attributes were mapped to Means, Timing, or Site categories of the nursing action model and 6 attributes were mapped to Degree or Judgment categories of the nursing diagnosis model. The findings suggest the need for an integrated RTM for nursing.

  3. Higher order point and continuum mechanics from phase-space action

    Energy Technology Data Exchange (ETDEWEB)

    Shamanna, J.; Talukdar, B.; Das, U

    2002-12-02

    It is pointed out that use of phase-space action provides an elegant method to study the canonical structure of problems in mechanics. Higher order Lagrangian systems are Hamiltonized by employing the variational principle in phase space. Studies are envisaged for both particle dynamics and field theory. Hamilton's equations are expressed in terms of appropriate Poisson brackets.

  4. Schild Action and Space-Time Uncertainty Principle in String Theory

    OpenAIRE

    Yoneya, Tamiaki

    1997-01-01

    We show that the path-integral quantization of relativistic strings with the Schild action is essentially equivalent to the usual Polyakov quantization at critical space-time dimensions. We then present an interpretation of the Schild action which points towards a derivation of superstring theory as a theory of quantized space-time where the squared string scale plays the role of the minimum quantum for space-time areas. A tentative approach towards such a goal is proposed, based on a microca...

  5. A Hybrid 3D Indoor Space Model

    Directory of Open Access Journals (Sweden)

    A. Jamali

    2016-10-01

    Full Text Available GIS integrates spatial information and spatial analysis. An important example of such integration is for emergency response which requires route planning inside and outside of a building. Route planning requires detailed information related to indoor and outdoor environment. Indoor navigation network models including Geometric Network Model (GNM, Navigable Space Model, sub-division model and regular-grid model lack indoor data sources and abstraction methods. In this paper, a hybrid indoor space model is proposed. In the proposed method, 3D modeling of indoor navigation network is based on surveying control points and it is less dependent on the 3D geometrical building model. This research proposes a method of indoor space modeling for the buildings which do not have proper 2D/3D geometrical models or they lack semantic or topological information. The proposed hybrid model consists of topological, geometrical and semantical space.

  6. Semantic Vector Space Model: Implementation and Evaluation.

    Science.gov (United States)

    Liu, Geoffrey Z.

    1997-01-01

    Presents the Semantic Vector Space Model, a text representation and searching technique based on the combination of Vector Space Model with heuristic syntax parsing and distributed representation of semantic case structures. In this model, both documents and queries are represented as semantic matrices, and retrieval is achieved by computing…

  7. Action preparation modulates sensory perception in unseen personal space: An electrophysiological investigation.

    Science.gov (United States)

    Job, Xavier E; de Fockert, Jan W; van Velzen, José

    2016-08-01

    Behavioural and electrophysiological evidence has demonstrated that preparation of goal-directed actions modulates sensory perception at the goal location before the action is executed. However, previous studies have focused on sensory perception in areas of peripersonal space. The present study investigated visual and tactile sensory processing at the goal location of upcoming movements towards the body, much of which is not visible, as well as visible peripersonal space. A motor task cued participants to prepare a reaching movement towards goals either in peripersonal space in front of them or personal space on the upper chest. In order to assess modulations of sensory perception during movement preparation, event-related potentials (ERPs) were recorded in response to task-irrelevant visual and tactile probe stimuli delivered randomly at one of the goal locations of the movements. In line with previous neurophysiological findings, movement preparation modulated visual processing at the goal of a movement in peripersonal space. Movement preparation also modulated somatosensory processing at the movement goal in personal space. The findings demonstrate that tactile perception in personal space is subject to similar top-down sensory modulation by motor preparation as observed for visual stimuli presented in peripersonal space. These findings show for the first time that the principles and mechanisms underlying adaptive modulation of sensory processing in the context of action extend to tactile perception in unseen personal space. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Enhanced integration of multisensory body information by proximity to "habitual action space".

    Science.gov (United States)

    Dempsey-Jones, Harriet; Kritikos, Ada

    2017-04-01

    Previous research suggests integration of visual and somatosensory inputs is enhanced within reaching (peripersonal) space. In such experiments, somatosensory inputs are presented on the body while visual inputs are moved relatively closer to, or further from the body. It is unclear, therefore, whether enhanced integration in "peripersonal space" is truly due to proximity of visual inputs to the body space, or, simply the distance between the inputs (which also affects integration). Using a modified induction of the rubber hand illusion, here we measured proprioceptive drift as an index of visuosomatosensory integration when distance between the two inputs was constrained, and absolute distance from the body was varied. Further, we investigated whether integration varies with proximity of inputs to the habitual action space of the arm-rather than the actual arm itself. In Experiment 1, integration was enhanced with inputs proximal to habitual action space, and reduced with lateral distance from this space. This was not attributable to an attentional or perceptual bias of external space because the pattern of proprioceptive drift was opposite for left and right hand illusions, that is, consistently maximal at the shoulder of origin (Experiment 2). We conclude that habitual patterns of action modulate visuosomatosensory integration. It appears multisensory integration is modulated in locations of space that are functionally relevant for behavior, whether an actual body part resides within that space or not. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  9. Model Spaces of Regularity Structures for Space-Fractional SPDEs

    Science.gov (United States)

    Berglund, Nils; Kuehn, Christian

    2017-07-01

    We study model spaces, in the sense of Hairer, for stochastic partial differential equations involving the fractional Laplacian. We prove that the fractional Laplacian is a singular kernel suitable to apply the theory of regularity structures. Our main contribution is to study the dependence of the model space for a regularity structure on the three-parameter problem involving the spatial dimension, the polynomial order of the nonlinearity, and the exponent of the fractional Laplacian. The goal is to investigate the growth of the model space under parameter variation. In particular, we prove several results in the approaching subcriticality limit leading to universal growth exponents of the regularity structure. A key role is played by the viewpoint that model spaces can be identified with families of rooted trees. Our proofs are based upon a geometrical construction similar to Newton polygons for classical Taylor series and various combinatorial arguments. We also present several explicit examples listing all elements with negative homogeneity by implementing a new symbolic software package to work with regularity structures. We use this package to illustrate our analytical results and to obtain new conjectures regarding coarse-grained network measures for model spaces.

  10. Shared Action Spaces: a basis function framework for social re-calibration of sensorimotor representations supporting joint action

    Directory of Open Access Journals (Sweden)

    Giovanni ePezzulo

    2013-11-01

    Full Text Available The article explores the possibilities of formalizing and explaining the mechanisms that support spatial and social perspective alignment sustained over the duration of a social interaction. The basic proposed principle is that in social contexts the mechanisms for sensorimotor transformations and multisensory integration (learn to incorporate information relative to the other actor(s, similar to the "re-calibration" of visual receptive fields in response to repeated tool use. This process aligns or merges the co-actors' spatial representations and creates a "Shared Action Space" supporting key computations of social interactions and joint actions; for example, the remapping between the coordinate systems and frames of reference of the co-actors, including perspective taking, the sensorimotor transformations required for lifting jointly an object, and the predictions of the sensory effects of such joint action. The social re-calibration is proposed to be based on common basis function maps and could constitute an optimal solution to sensorimotor transformation and multisensory integration in joint action or more in general social interaction contexts. However, certain situations such as discrepant postural and viewpoint alignment and associated differences in perspectives between the co-actors could constrain the process quite differently. We discuss how alignment is achieved in the first place, and how it is maintained over time, providing a taxonomy of various forms and mechanisms of space alignment and overlap based, for instance, on automaticity vs. control of the transformations between the two agents. Finally, we discuss the link between low-level mechanisms for the sharing of space and high-level mechanisms for the sharing of cognitive representations.

  11. Spatial and frequency domain ring source models for the single muscle fiber action potential

    DEFF Research Database (Denmark)

    Henneberg, Kaj-åge; R., Plonsey

    1994-01-01

    In the paper, single-fibre models for the extracellular action potential are developed that will allow the potential to the evaluated at an arbitrary field point in the extracellular space. Fourier-domain models are restricted in that they evaluate potentials at equidistant points along a line...

  12. Measurement Models for Reasoned Action Theory

    OpenAIRE

    Hennessy, Michael; Bleakley, Amy; Fishbein, Martin

    2012-01-01

    Quantitative researchers distinguish between causal and effect indicators. What are the analytic problems when both types of measures are present in a quantitative reasoned action analysis? To answer this question, we use data from a longitudinal study to estimate the association between two constructs central to reasoned action theory: behavioral beliefs and attitudes toward the behavior. The belief items are causal indicators that define a latent variable index while the attitude items are ...

  13. Defining Learning Space in a Serious Game in Terms of Operative and Resultant Actions

    Science.gov (United States)

    Martin, Michael W.; Shen, Yuzhong

    2012-01-01

    This paper explores the distinction between operative and resultant actions in games, and proposes that the learning space created by a serious game is a function of these actions. Further, it suggests a possible relationship between these actions and the forms of cognitive load imposed upon the game player. Association of specific types of cognitive load with respective forms of actions in game mechanics also presents some heuristics for integrating learning content into serious games. Research indicates that different balances of these types of actions are more suitable for novice or experienced learners. By examining these relationships, we can develop a few basic principles of game design which have an increased potential to promote positive learning outcomes.

  14. The cohomology of orbit spaces of certain free circle group actions

    Indian Academy of Sciences (India)

    Abstract. Suppose that G = S1 acts freely on a finitistic space X whose (mod p) cohomology ring is isomorphic to that of a lens space L2m−1(p;q1,...,qm) or S1 ×. CPm−1. The mod p index of the action is defined to be the largest integer n such that αn = 0, where α ϵ H2(X/G; Zp) is the nonzero characteristic class of the S1-.

  15. Measurement Models for Reasoned Action Theory.

    Science.gov (United States)

    Hennessy, Michael; Bleakley, Amy; Fishbein, Martin

    2012-03-01

    Quantitative researchers distinguish between causal and effect indicators. What are the analytic problems when both types of measures are present in a quantitative reasoned action analysis? To answer this question, we use data from a longitudinal study to estimate the association between two constructs central to reasoned action theory: behavioral beliefs and attitudes toward the behavior. The belief items are causal indicators that define a latent variable index while the attitude items are effect indicators that reflect the operation of a latent variable scale. We identify the issues when effect and causal indicators are present in a single analysis and conclude that both types of indicators can be incorporated in the analysis of data based on the reasoned action approach.

  16. Space Vehicle Reliability Modeling in DIORAMA

    Energy Technology Data Exchange (ETDEWEB)

    Tornga, Shawn Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-07-12

    When modeling system performance of space based detection systems it is important to consider spacecraft reliability. As space vehicles age the components become prone to failure for a variety of reasons such as radiation damage. Additionally, some vehicles may lose the ability to maneuver once they exhaust fuel supplies. Typically failure is divided into two categories: engineering mistakes and technology surprise. This document will report on a method of simulating space vehicle reliability in the DIORAMA framework.

  17. Can Participatory Action Research Create Value for Business Model Innovation?

    DEFF Research Database (Denmark)

    Sparre, Mogens; Rasmussen, Ole Horn; Fast, Alf Michael

    Abstract: Participatory Action Research (PAR) has a longer academic history compared with the idea of business models (BMs). This paper indicates how industries gain by using the combined methodology. The research question "Can participatory action research create value for Business Model...

  18. Momentum-space Harper-Hofstadter model

    Science.gov (United States)

    Ozawa, Tomoki; Price, Hannah M.; Carusotto, Iacopo

    2015-08-01

    We show how the weakly trapped Harper-Hofstadter model can be mapped onto a Harper-Hofstadter model in momentum space. In this momentum-space model, the band dispersion plays the role of the periodic potential, the Berry curvature plays the role of an effective magnetic field, the real-space harmonic trap provides the momentum-space kinetic energy responsible for the hopping, and the trap position sets the boundary conditions around the magnetic Brillouin zone. Spatially local interactions translate into nonlocal interactions in momentum space: within a mean-field approximation, we show that increasing interparticle interactions leads to a structural change of the ground state, from a single rotationally symmetric ground state to degenerate ground states that spontaneously break rotational symmetry.

  19. Multimedia Mapping using Continuous State Space Models

    DEFF Research Database (Denmark)

    Lehn-Schiøler, Tue

    2004-01-01

    In this paper a system that transforms speech waveforms to animated faces are proposed. The system relies on continuous state space models to perform the mapping, this makes it possible to ensure video with no sudden jumps and allows continuous control of the parameters in 'face space'. Simulatio...

  20. The Learning of Visually Guided Action: An Information-Space Analysis of Pole Balancing

    Science.gov (United States)

    Jacobs, David M.; Vaz, Daniela V.; Michaels, Claire F.

    2012-01-01

    In cart-pole balancing, one moves a cart in 1 dimension so as to balance an attached inverted pendulum. We approached perception-action and learning in this task from an ecological perspective. This entailed identifying a space of informational variables that balancers use as they perform the task and demonstrating that they improve by traversing…

  1. Models for multimegawatt space power systems

    Energy Technology Data Exchange (ETDEWEB)

    Edenburn, M.W.

    1990-06-01

    This report describes models for multimegawatt, space power systems which Sandia's Advanced Power Systems Division has constructed to help evaluate space power systems for SDI's Space Power Office. Five system models and models for associated components are presented for both open (power system waste products are exhausted into space) and closed (no waste products) systems: open, burst mode, hydrogen cooled nuclear reactor -- turboalternator system; open, hydrogen-oxygen combustion turboalternator system; closed, nuclear reactor powered Brayton cycle system; closed, liquid metal Rankine cycle system; and closed, in-core, reactor therminonic system. The models estimate performance and mass for the components in each of these systems. 17 refs., 8 figs., 15 tabs.

  2. My Life with State Space Models

    DEFF Research Database (Denmark)

    Lundbye-Christensen, Søren

    2007-01-01

    State space models have had a tremendous impact on the analysis of time series. Even though the models and ideas are much older the work that Mike West and others started in the 1980ies brought the attention to the statisticians and the models and inferential possibilities have developed enormous...

  3. Parametric cost models for space telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtnay

    2017-11-01

    Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

  4. Parametric Cost Models for Space Telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtney

    2010-01-01

    Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

  5. Validation of Space Weather Models at Community Coordinated Modeling Center

    Science.gov (United States)

    Kuznetsova, M. M.; Hesse, M.; Pulkkinen, A.; Maddox, M.; Rastaetter, L.; Berrios, D.; Zheng, Y.; MacNeice, P. J.; Shim, J.; Taktakishvili, A.; hide

    2011-01-01

    The Community Coordinated Modeling Center (CCMC) is a multi-agency partnership to support the research and developmental work necessary to substantially increase space weather modeling capabilities and to facilitate advanced models deployment in forecasting operations. Space weather models and coupled model chains hosted at the CCMC range from the solar corona to the Earth's upper atmosphere. CCMC has developed a number of real-time modeling systems, as well as a large number of modeling and data products tailored to address the space weather needs of NASA's robotic missions. The CCMC conducts unbiased model testing and validation and evaluates model readiness for operational environment. CCMC has been leading recent comprehensive modeling challenges under GEM, CEDAR and SHINE programs. The presentation will focus on experience in carrying out comprehensive and systematic validation of large sets of. space weather models

  6. Modeling the value of strategic actions in the superior colliculus

    Directory of Open Access Journals (Sweden)

    Dhushan Thevarajah

    2010-02-01

    Full Text Available In learning models of strategic game play, an agent constructs a valuation (action value over possible future choices as a function of past actions and rewards. Choices are then stochastic functions of these action values. Our goal is to uncover a neural signal that correlates with the action value posited by behavioral learning models. We measured activity from neurons in the superior colliculus (SC, a midbrain region involved in planning saccadic eye movements, in monkeys while they performed two saccade tasks. In the strategic task, monkeys competed against a computer in a saccade version of the mixed-strategy game “matching-pennies”. In the instructed task, stochastic saccades were elicited through explicit instruction rather than free choices. In both tasks, neuronal activity and behavior were shaped by past actions and rewards with more recent events exerting a larger influence. Further, SC activity predicted upcoming choices during the strategic task and upcoming reaction times during the instructed task. Finally, we found that neuronal activity in both tasks correlated with an established learning model, the Experience Weighted Attraction model of action valuation (Ho, Camerer, and Chong, 2007. Collectively, our results provide evidence that action values hypothesized by learning models are represented in the motor planning regions of the brain in a manner that could be used to select strategic actions.

  7. Modeling the value of strategic actions in the superior colliculus.

    Science.gov (United States)

    Thevarajah, Dhushan; Webb, Ryan; Ferrall, Christopher; Dorris, Michael C

    2010-01-01

    In learning models of strategic game play, an agent constructs a valuation (action value) over possible future choices as a function of past actions and rewards. Choices are then stochastic functions of these action values. Our goal is to uncover a neural signal that correlates with the action value posited by behavioral learning models. We measured activity from neurons in the superior colliculus (SC), a midbrain region involved in planning saccadic eye movements, while monkeys performed two saccade tasks. In the strategic task, monkeys competed against a computer in a saccade version of the mixed-strategy game "matching-pennies". In the instructed task, saccades were elicited through explicit instruction rather than free choices. In both tasks neuronal activity and behavior were shaped by past actions and rewards with more recent events exerting a larger influence. Further, SC activity predicted upcoming choices during the strategic task and upcoming reaction times during the instructed task. Finally, we found that neuronal activity in both tasks correlated with an established learning model, the Experience Weighted Attraction model of action valuation (Camerer and Ho, 1999). Collectively, our results provide evidence that action values hypothesized by learning models are represented in the motor planning regions of the brain in a manner that could be used to select strategic actions.

  8. Space Environments and Effects: Trapped Proton Model

    Science.gov (United States)

    Huston, S. L.; Kauffman, W. (Technical Monitor)

    2002-01-01

    An improved model of the Earth's trapped proton environment has been developed. This model, designated Trapped Proton Model version 1 (TPM-1), determines the omnidirectional flux of protons with energy between 1 and 100 MeV throughout near-Earth space. The model also incorporates a true solar cycle dependence. The model consists of several data files and computer software to read them. There are three versions of the mo'del: a FORTRAN-Callable library, a stand-alone model, and a Web-based model.

  9. The STAMP Software for State Space Models

    Directory of Open Access Journals (Sweden)

    Roy Mendelssohn

    2011-05-01

    Full Text Available This paper reviews the use of STAMP (Structural Time Series Analyser, Modeler and Predictor for modeling time series data using state-space methods with unobserved components. STAMP is a commercial, GUI-based program that runs on Windows, Linux and Macintosh computers as part of the larger OxMetrics System. STAMP can estimate a wide-variety of both univariate and multivariate state-space models, provides a wide array of diagnostics, and has a batch mode capability. The use of STAMP is illustrated for the Nile river data which is analyzed throughout this issue, as well as by modeling a variety of oceanographic and climate related data sets. The analyses of the oceanographic and climate data illustrate the breadth of models available in STAMP, and that state-space methods produce results that provide new insights into important scientific problems.

  10. Deep space network software cost estimation model

    Science.gov (United States)

    Tausworthe, R. C.

    1981-01-01

    A parametric software cost estimation model prepared for Jet PRopulsion Laboratory (JPL) Deep Space Network (DSN) Data System implementation tasks is described. The resource estimation mdel modifies and combines a number of existing models. The model calibrates the task magnitude and difficulty, development environment, and software technology effects through prompted responses to a set of approximately 50 questions. Parameters in the model are adjusted to fit JPL software life-cycle statistics.

  11. A continuous-time neural model for sequential action.

    Science.gov (United States)

    Kachergis, George; Wyatte, Dean; O'Reilly, Randall C; de Kleijn, Roy; Hommel, Bernhard

    2014-11-05

    Action selection, planning and execution are continuous processes that evolve over time, responding to perceptual feedback as well as evolving top-down constraints. Existing models of routine sequential action (e.g. coffee- or pancake-making) generally fall into one of two classes: hierarchical models that include hand-built task representations, or heterarchical models that must learn to represent hierarchy via temporal context, but thus far lack goal-orientedness. We present a biologically motivated model of the latter class that, because it is situated in the Leabra neural architecture, affords an opportunity to include both unsupervised and goal-directed learning mechanisms. Moreover, we embed this neurocomputational model in the theoretical framework of the theory of event coding (TEC), which posits that actions and perceptions share a common representation with bidirectional associations between the two. Thus, in this view, not only does perception select actions (along with task context), but actions are also used to generate perceptions (i.e. intended effects). We propose a neural model that implements TEC to carry out sequential action control in hierarchically structured tasks such as coffee-making. Unlike traditional feedforward discrete-time neural network models, which use static percepts to generate static outputs, our biological model accepts continuous-time inputs and likewise generates non-stationary outputs, making short-timescale dynamic predictions. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  12. Modeling color preference using color space metrics.

    Science.gov (United States)

    Schloss, Karen B; Lessard, Laurent; Racey, Chris; Hurlbert, Anya C

    2017-07-27

    Studying color preferences provides a means to discover how perceptual experiences map onto cognitive and affective judgments. A challenge is finding a parsimonious way to describe and predict patterns of color preferences, which are complex with rich individual differences. One approach has been to model color preferences using factors from metric color spaces to establish direct correspondences between dimensions of color and preference. Prior work established that substantial, but not all, variance in color preferences could be captured by weights on color space dimensions using multiple linear regression. The question we address here is whether model fits may be improved by using different color metric specifications. We therefore conducted a large-scale analysis of color space models, and focused in-depth analysis on models that differed in color space (cone-contrast vs. CIELAB), coordinate system within the color space (Cartesian vs. cylindrical), and factor degrees (1st degree only, or 1st and 2nd degree). We used k-fold cross validation to avoid over-fitting the data and to ensure fair comparisons across models. The best model was the 2nd-harmonic Lch model ("LabC Cyl2"). Specified in CIELAB space, it included 1st and 2nd harmonics of hue (capturing opponency in hue preferences and simultaneous liking/disliking of both hues on an opponent axis, respectively), lightness, and chroma. These modeling approaches can be used to characterize and compare patterns for group averages and individuals in future datasets on color preference, or other measures in which correspondences between color appearance and cognitive or affective judgments may exist. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Computerised analysis of sulphate action on model concrete piles

    Digital Repository Service at National Institute of Oceanography (India)

    Deshmukh, A.M.; Balasubramanian, S.; Venugopal, C.

    the influence of magnesium sulphate on model reinforced concrete piles. The sulphate action on the corrosion rate of rebar in concrete has been distinctly studied through sophisticated computerised potentiodynamic technique. The corrosion of rebar has been...

  14. Decision modeling for analyzing fire action outcomes

    Science.gov (United States)

    Donald MacGregor; Armando Gonzalez-Caban

    2008-01-01

    A methodology for incident decomposition and reconstruction is developed based on the concept of an "event-frame model." The event-frame model characterizes a fire incident in terms of (a) environmental events that pertain to the fire and the fire context (e.g., fire behavior, weather, fuels) and (b) management events that represent responses to the fire...

  15. Qualitative models for space system engineering

    Science.gov (United States)

    Forbus, Kenneth D.

    1990-01-01

    The objectives of this project were: (1) to investigate the implications of qualitative modeling techniques for problems arising in the monitoring, diagnosis, and design of Space Station subsystems and procedures; (2) to identify the issues involved in using qualitative models to enhance and automate engineering functions. These issues include representing operational criteria, fault models, alternate ontologies, and modeling continuous signals at a functional level of description; and (3) to develop a prototype collection of qualitative models for fluid and thermal systems commonly found in Space Station subsystems. Potential applications of qualitative modeling to space-systems engineering, including the notion of intelligent computer-aided engineering are summarized. Emphasis is given to determining which systems of the proposed Space Station provide the most leverage for study, given the current state of the art. Progress on using qualitative models, including development of the molecular collection ontology for reasoning about fluids, the interaction of qualitative and quantitative knowledge in analyzing thermodynamic cycles, and an experiment on building a natural language interface to qualitative reasoning is reported. Finally, some recommendations are made for future research.

  16. A Model of Microevolution in Action.

    Science.gov (United States)

    Welch, Larry A.

    1993-01-01

    Presents an activity to help students understand the precepts of the Hardy-Weinberg principle and simultaneously permit observation of a model of evolution through natural selection in a nonthreatening setting. (PR)

  17. Quadratic adaptive algorithm for solving cardiac action potential models.

    Science.gov (United States)

    Chen, Min-Hung; Chen, Po-Yuan; Luo, Ching-Hsing

    2016-10-01

    An adaptive integration method is proposed for computing cardiac action potential models accurately and efficiently. Time steps are adaptively chosen by solving a quadratic formula involving the first and second derivatives of the membrane action potential. To improve the numerical accuracy, we devise an extremum-locator (el) function to predict the local extremum when approaching the peak amplitude of the action potential. In addition, the time step restriction (tsr) technique is designed to limit the increase in time steps, and thus prevent the membrane potential from changing abruptly. The performance of the proposed method is tested using the Luo-Rudy phase 1 (LR1), dynamic (LR2), and human O'Hara-Rudy dynamic (ORd) ventricular action potential models, and the Courtemanche atrial model incorporating a Markov sodium channel model. Numerical experiments demonstrate that the action potential generated using the proposed method is more accurate than that using the traditional Hybrid method, especially near the peak region. The traditional Hybrid method may choose large time steps near to the peak region, and sometimes causes the action potential to become distorted. In contrast, the proposed new method chooses very fine time steps in the peak region, but large time steps in the smooth region, and the profiles are smoother and closer to the reference solution. In the test on the stiff Markov ionic channel model, the Hybrid blows up if the allowable time step is set to be greater than 0.1ms. In contrast, our method can adjust the time step size automatically, and is stable. Overall, the proposed method is more accurate than and as efficient as the traditional Hybrid method, especially for the human ORd model. The proposed method shows improvement for action potentials with a non-smooth morphology, and it needs further investigation to determine whether the method is helpful during propagation of the action potential. Copyright © 2016 Elsevier Ltd. All rights

  18. Gene dosage imbalances: action, reaction, and models.

    Science.gov (United States)

    Veitia, Reiner A; Potier, Marie Claude

    2015-06-01

    Single-gene deletions, duplications, and misregulation, as well as aneuploidy, can lead to stoichiometric imbalances within macromolecular complexes and cellular networks, causing their malfunction. Such alterations can be responsible for inherited or somatic genetic disorders including Mendelian diseases, aneuploid syndromes, and cancer. We review the effects of gene dosage alterations at the transcriptomic and proteomic levels, and the various responses of the cell to counteract their effects. Furthermore, we explore several biochemical models and ideas that can provide the rationale for treatments modulating the effects of gene dosage imbalances. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Multivariable Wind Modeling in State Space

    DEFF Research Database (Denmark)

    Sichani, Mahdi Teimouri; Pedersen, B. J.

    2011-01-01

    Turbulence of the incoming wind field is of paramount importance to the dynamic response of wind turbines. Hence reliable stochastic models of the turbulence should be available from which time series can be generated for dynamic response and structural safety analysis. In the paper an empirical...... cross-spectral density function for the along-wind turbulence component over the rotor plane is taken as the starting point. The spectrum is spatially discretized in terms of a Hermitian cross-spectral density matrix for the turbulence state vector which turns out not to be positive definite. Since......-spectral density matrix a frequency response matrix is constructed which determines the turbulence vector as a linear filtration of Gaussian white noise. Finally, an accurate state space modeling method is proposed which allows selection of an appropriate model order, and estimation of a state space model...

  20. Space-time modeling of timber prices

    Science.gov (United States)

    Mo Zhou; Joseph Buongriorno

    2006-01-01

    A space-time econometric model was developed for pine sawtimber timber prices of 21 geographically contiguous regions in the southern United States. The correlations between prices in neighboring regions helped predict future prices. The impulse response analysis showed that although southern pine sawtimber markets were not globally integrated, local supply and demand...

  1. Space Particle Hazard Measurement and Modeling

    Science.gov (United States)

    2016-09-01

    rejection. The method was applied to data obtained by the Relativistic Electron-Proton Telescopes (REPT) on the Van Allen Probes satellites, providing new...capabilities of current instrumentation [37]. Van Allen Probe data continued to be evaluated to remove contamination and compared to models. Evaluated...AFRL/RVBX performed substantial research and development in the areas of the AE9/AP9/SPM standard radiation belt model, energetic space particle

  2. Habitability Concept Models for Living in Space

    Science.gov (United States)

    Ferrino, M.

    2002-01-01

    As growing trends show, living in "space" has acquired new meanings, especially considering the utilization of the International Space Station (ISS) with regard to group interaction as well as individual needs in terms of time, space and crew accommodations. In fact, for the crew, the Spaced Station is a combined Laboratory-Office/Home and embodies ethical, social, and cultural aspects as additional parameters to be assessed to achieve a user centered architectural design of crew workspace. Habitability Concept Models can improve the methods and techniques used to support the interior design and layout of space architectures and at the same time guarantee a human focused approach. This paper discusses and illustrates some of the results obtained for the interior design of a Habitation Module for the ISS. In this work, two different but complementary approaches are followed. The first is "object oriented" and based on Video Data (American and Russian) supported by Proxemic methods (Edward T. Hall, 1963 and Francesca Pregnolato, 1998). This approach offers flexible and adaptive design solutions. The second is "subject oriented" and based on a Virtual Reality environment. With this approach human perception and cognitive aspects related to a specific crew task are considered. Data obtained from these two approaches are used to verify requirements and advance the design of the Habitation Module for aspects related to man machine interfaces (MMI), ergonomics, work and free-time. It is expected that the results achieved can be applied to future space related projects.

  3. Dynamic modelling and analysis of space webs

    Science.gov (United States)

    Yu, Yang; Baoyin, HeXi; Li, JunFeng

    2011-04-01

    Future space missions demand operations on large flexible structures, for example, space webs, the lightweight cable nets deployable in space, which can serve as platforms for very large structures or be used to capture orbital objects. The interest in research on space webs is likely to increase in the future with the development of promising applications such as Furoshiki sat-ellite of JAXA, Robotic Geostationary Orbit Restorer (ROGER) of ESA and Grapple, Retrieve And Secure Payload (GRASP) of NASA. Unlike high-tensioned nets in civil engineering, space webs may be low-tensioned or tensionless, and extremely flexible, owing to the microgravity in the orbit and the lack of support components, which may cause computational difficulties. Mathematical models are necessary in the analysis of space webs, especially in the conceptual design and evaluation for prototypes. A full three-dimensional finite element (FE) model was developed in this work. Trivial truss elements were adopted to reduce the computational complexity. Considering cable is a compression-free material and its tensile stiffness is also variable, we introduced the cable material constitutive relationship to work out an accurate and feasible model for prototype analysis and design. In the static analysis, the stress distribution and global deformation of the webs were discussed to get access to the knowledge of strength of webs with different types of meshes. In the dynamic analysis, special attention was paid to the impact problem. The max stress and global deformation were investigated. The simulation results indicate the interesting phenomenon which may be worth further research.

  4. A computational model of perception and action for cognitive robotics.

    Science.gov (United States)

    Haazebroek, Pascal; van Dantzig, Saskia; Hommel, Bernhard

    2011-11-01

    Robots are increasingly expected to perform tasks in complex environments. To this end, engineers provide them with processing architectures that are based on models of human information processing. In contrast to traditional models, where information processing is typically set up in stages (i.e., from perception to cognition to action), it is increasingly acknowledged by psychologists and robot engineers that perception and action are parts of an interactive and integrated process. In this paper, we present HiTEC, a novel computational (cognitive) model that allows for direct interaction between perception and action as well as for cognitive control, demonstrated by task-related attentional influences. Simulation results show that key behavioral studies can be readily replicated. Three processing aspects of HiTEC are stressed for their importance for cognitive robotics: (1) ideomotor learning of action control, (2) the influence of task context and attention on perception, action planning, and learning, and (3) the interaction between perception and action planning. Implications for the design of cognitive robotics are discussed.

  5. The Complex Action Recognition via the Correlated Topic Model

    Directory of Open Access Journals (Sweden)

    Hong-bin Tu

    2014-01-01

    Full Text Available Human complex action recognition is an important research area of the action recognition. Among various obstacles to human complex action recognition, one of the most challenging is to deal with self-occlusion, where one body part occludes another one. This paper presents a new method of human complex action recognition, which is based on optical flow and correlated topic model (CTM. Firstly, the Markov random field was used to represent the occlusion relationship between human body parts in terms of an occlusion state variable. Secondly, the structure from motion (SFM is used for reconstructing the missing data of point trajectories. Then, we can extract the key frame based on motion feature from optical flow and the ratios of the width and height are extracted by the human silhouette. Finally, we use the topic model of correlated topic model (CTM to classify action. Experiments were performed on the KTH, Weizmann, and UIUC action dataset to test and evaluate the proposed method. The compared experiment results showed that the proposed method was more effective than compared methods.

  6. Cosmological Models with Fractional Derivatives and Fractional Action Functional

    OpenAIRE

    Shchigolev, V. K.

    2010-01-01

    Cosmological models of a scalar field with dynamical equations containing fractional derivatives or derived from the Einstein-Hilbert action of fractional order, are constructed. A number of exact solutions to those equations of fractional cosmological models in both cases is given.

  7. Space market model development project, phase 3

    Science.gov (United States)

    Bishop, Peter C.; Hamel, Gary P.

    1989-01-01

    The results of a research project investigating information needs for space commercialization is described. The Space Market Model Development Project (SMMDP) was designed to help NASA identify the information needs of the business community and to explore means to meet those needs. The activity of the SMMDP is reviewed and a report of its operation via three sections is presented. The first part contains a brief historical review of the project since inception. The next part reports results of Phase 3, the most recent stage of activity. Finally, overall conclusions and observations based on the SMMDP research results are presented.

  8. A simplified model of collision-driven dynamo action in small bodies

    CERN Document Server

    Wei, Xing

    2013-01-01

    We investigate numerically the self-sustained dynamo action in a spinning sphere whose sense of rotation reverses periodically. This system serves as a simple model of a dynamo in small bodies powered by frequent collisions. It is found that dynamo action is possible in some intervals of collision rates. At high Ekman numbers the laminar spin-up flow is helical in the boundary layers and the Ekman circulation together with the azimuthal shear powers the dynamo action. At low Ekman number a non-axisymmetric instability helps the dynamo action. The intermittency of magnetic field occurs at low Ekman number. A lower bound of magnetic energy is numerically obtained, and the space-averaged field in the fluid core and the surface field of a small body are roughly estimated.

  9. Legal and Political Implications of Offensive Actions from and Against the Space Segment

    Science.gov (United States)

    de Angelis, Iole M.

    2002-01-01

    deployment of strategic weapons, kinetic energy weapons and directed energy weapons are already contained within existing rules and such issues are being actively addressed by the international community. At the same time, the use of cyberwar and electronic warfare to counter space technology not only encounters a void of international rules, but it is a question that is very rarely taken into consideration while addressing to the issues of preventing space warfare. Finally, these techniques are easily available to non-state organisations - terrorist organisations and commercial companies - and individuals. In conclusion, the issues related to offensive actions towards and from space shall be taken into consideration not only in a military perspective, but also in a political perspective - terrorist actions against the space segment - and from an economical point of view.

  10. Modeling Space Radiation with Radiomimetic Agent Bleomycin

    Science.gov (United States)

    Lu, Tao

    2017-01-01

    Space radiation consists of proton and helium from solar particle events (SPE) and high energy heavy ions from galactic cosmic ray (GCR). This mixture of radiation with particles at different energy levels has different effects on biological systems. Currently, majority studies of radiation effects on human were based on single-source radiation due to the limitation of available method to model effects of space radiation on living organisms. While NASA Space Radiation Laboratory is working on advanced switches to make it possible to have a mixed field radiation with particles of different energies, the radiation source will be limited. Development of an easily available experimental model for studying effects of mixed field radiation could greatly speed up our progress in our understanding the molecular mechanisms of damage and responses from exposure to space radiation, and facilitate the discovery of protection and countermeasures against space radiation, which is critical for the mission to Mars. Bleomycin, a radiomimetic agent, has been widely used to study radiation induced DNA damage and cellular responses. Previously, bleomycin was often compared to low low Linear Energy Transfer (LET) gamma radiation without defined characteristics. Our recent work demonstrated that bleomycin could induce complex clustered DNA damage in human fibroblasts that is similar to DNA damage induced by high LET radiation. These type of DNA damage is difficult to repair and can be visualized by gamma-H2Ax staining weeks after the initial insult. The survival ratio between early and late plating of human fibroblasts after bleomycin treatment is between low LET and high LET radiation. Our results suggest that bleomycin induces DNA damage and other cellular stresses resembling those resulted from mixed field radiation with both low and high LET particles. We hypothesize that bleomycin could be used to mimic space radiation in biological systems. Potential advantages and limitations of

  11. Model-based hierarchical reinforcement learning and human action control.

    Science.gov (United States)

    Botvinick, Matthew; Weinstein, Ari

    2014-11-05

    Recent work has reawakened interest in goal-directed or 'model-based' choice, where decisions are based on prospective evaluation of potential action outcomes. Concurrently, there has been growing attention to the role of hierarchy in decision-making and action control. We focus here on the intersection between these two areas of interest, considering the topic of hierarchical model-based control. To characterize this form of action control, we draw on the computational framework of hierarchical reinforcement learning, using this to interpret recent empirical findings. The resulting picture reveals how hierarchical model-based mechanisms might play a special and pivotal role in human decision-making, dramatically extending the scope and complexity of human behaviour.

  12. On the cohomology of orbit space of free Zp Zp Zp-actions on lens ...

    Indian Academy of Sciences (India)

    sphere. S2m−1 ⊂ C ×···× C (m-times). Given integers q1,...,qm relatively prime to p, the map (ξ1,...,ξm) → (ζq1 ξ1,...,ζqm ξm), where ζ = e2πι/p2. , defines a free action of. G = 〈ζ〉 on S2m−1 . The orbit spaces of G and the subgroup N = 〈ζp〉 are ...

  13. Can Participatory Action Research Create Value for Business Model Innovation?

    DEFF Research Database (Denmark)

    Sparre, Mogens; Rasmussen, Ole Horn; Fast, Alf Michael

    Abstract: Participatory Action Research (PAR) has a longer academic history compared with the idea of business models (BMs). This paper indicates how industries gain by using the combined methodology. The research question "Can participatory action research create value for Business Model...... their monetary and/or non-monetary value creation doing BMI based upon PAR. The process is essential and using the methodology of PAR creates meaning. Behind the process, the RAR methodology and its link to BM and BMI may contribute to theory construction and creation of a common language in academia around...

  14. THE ACTION MODEL FOR MEASURING INFLUENCE IN ADVERTISING

    Directory of Open Access Journals (Sweden)

    Andrej Kovacic

    2014-09-01

    Full Text Available Despite the abundance of different theories there is little agreement on the suitable model that would explain how influence in advertising works. Historically, theoretical models have moved from including solely rational components towards including emotional components and from focusing on sequential processing towards hierarchy free processing models. Based on the existing literature, several most representative models are presented, described and evaluated. In a quest to explain a broader view on advertising influence we introduced the ACTION model (an acronym for Aim, Connection, Techniques, Identity, Opportunity and Numerous. Advantages, suggestions for future research and a critical discussion of using this model are further discussed.

  15. Epistemic Learning Programs A Calculus for Describing Epistemic Action Models

    OpenAIRE

    Ramezanian, Mohammad Ardeshir Rasoul

    2013-01-01

    Dynamic Epistemic Logic makes it possible to model and reason about information change in multi-agent systems. Information change is mathematically modeled through epistemic action Kripke models introduced by Baltag et al. Also, van Ditmarsch interprets the information change as a relation between epistemic states and sets of epistemic states and to describe it formally, he considers a special constructor LB called learning operator. Inspired by this, it seems natural to us that the basic sou...

  16. Modelling of Patterns in Space and Time

    CERN Document Server

    Murray, James

    1984-01-01

    This volume contains a selection of papers presented at the work­ shop "Modelling of Patterns in Space and Time", organized by the 80nderforschungsbereich 123, "8tochastische Mathematische Modelle", in Heidelberg, July 4-8, 1983. The main aim of this workshop was to bring together physicists, chemists, biologists and mathematicians for an exchange of ideas and results in modelling patterns. Since the mathe­ matical problems arising depend only partially on the particular field of applications the interdisciplinary cooperation proved very useful. The workshop mainly treated phenomena showing spatial structures. The special areas covered were morphogenesis, growth in cell cultures, competition systems, structured populations, chemotaxis, chemical precipitation, space-time oscillations in chemical reactors, patterns in flames and fluids and mathematical methods. The discussions between experimentalists and theoreticians were especially interesting and effective. The editors hope that these proceedings reflect ...

  17. Access Nets: Modeling Access to Physical Spaces

    Science.gov (United States)

    Frohardt, Robert; Chang, Bor-Yuh Evan; Sankaranarayanan, Sriram

    Electronic, software-managed mechanisms using, for example, radio-frequency identification (RFID) cards, enable great flexibility in specifying access control policies to physical spaces. For example, access rights may vary based on time of day or could differ in normal versus emergency situations. With such fine-grained control, understanding and reasoning about what a policy permits becomes surprisingly difficult requiring knowledge of permission levels, spatial layout, and time. In this paper, we present a formal modeling framework, called AccessNets, suitable for describing a combination of access permissions, physical spaces, and temporal constraints. Furthermore, we provide evidence that model checking techniques are effective in reasoning about physical access control policies. We describe our results from a tool that uses reachability analysis to validate security policies.

  18. Data Model Management for Space Information Systems

    Science.gov (United States)

    Hughes, J. Steven; Crichton, Daniel J.; Ramirez, Paul; Mattmann, chris

    2006-01-01

    The Reference Architecture for Space Information Management (RASIM) suggests the separation of the data model from software components to promote the development of flexible information management systems. RASIM allows the data model to evolve independently from the software components and results in a robust implementation that remains viable as the domain changes. However, the development and management of data models within RASIM are difficult and time consuming tasks involving the choice of a notation, the capture of the model, its validation for consistency, and the export of the model for implementation. Current limitations to this approach include the lack of ability to capture comprehensive domain knowledge, the loss of significant modeling information during implementation, the lack of model visualization and documentation capabilities, and exports being limited to one or two schema types. The advent of the Semantic Web and its demand for sophisticated data models has addressed this situation by providing a new level of data model management in the form of ontology tools. In this paper we describe the use of a representative ontology tool to capture and manage a data model for a space information system. The resulting ontology is implementation independent. Novel on-line visualization and documentation capabilities are available automatically, and the ability to export to various schemas can be added through tool plug-ins. In addition, the ingestion of data instances into the ontology allows validation of the ontology and results in a domain knowledge base. Semantic browsers are easily configured for the knowledge base. For example the export of the knowledge base to RDF/XML and RDFS/XML and the use of open source metadata browsers provide ready-made user interfaces that support both text- and facet-based search. This paper will present the Planetary Data System (PDS) data model as a use case and describe the import of the data model into an ontology tool

  19. Space Weather: Measurements, Models and Predictions

    Science.gov (United States)

    2014-03-21

    AFRL-RV-PS- AFRL-RV-PS- TR-2014-0041 TR-2014-0041 SPACE WEATHER: MEASUREMENTS, MODELS AND PREDICTIONS Patricia H. Doherty, et al...GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 61102F 6. AUTHOR(S) Patricia H. Doherty, David Webb, Stuart Huston, Thomas Kuchar, Donald Mizuno...events are useful for the calibration of proton detectors because they bathe the outer magnetosphere (beyond Lm ~ 6.6) in a relatively uniform flux of

  20. Space-time modeling of soil moisture

    Science.gov (United States)

    Chen, Zijuan; Mohanty, Binayak P.; Rodriguez-Iturbe, Ignacio

    2017-11-01

    A physically derived space-time mathematical representation of the soil moisture field is carried out via the soil moisture balance equation driven by stochastic rainfall forcing. The model incorporates spatial diffusion and in its original version, it is shown to be unable to reproduce the relative fast decay in the spatial correlation functions observed in empirical data. This decay resulting from variations in local topography as well as in local soil and vegetation conditions is well reproduced via a jitter process acting multiplicatively over the space-time soil moisture field. The jitter is a multiplicative noise acting on the soil moisture dynamics with the objective to deflate its correlation structure at small spatial scales which are not embedded in the probabilistic structure of the rainfall process that drives the dynamics. These scales of order of several meters to several hundred meters are of great importance in ecohydrologic dynamics. Properties of space-time correlation functions and spectral densities of the model with jitter are explored analytically, and the influence of the jitter parameters, reflecting variabilities of soil moisture at different spatial and temporal scales, is investigated. A case study fitting the derived model to a soil moisture dataset is presented in detail.

  1. Learning atomic human actions using variable-length Markov models.

    Science.gov (United States)

    Liang, Yu-Ming; Shih, Sheng-Wen; Shih, Arthur Chun-Chieh; Liao, Hong-Yuan Mark; Lin, Cheng-Chung

    2009-02-01

    Visual analysis of human behavior has generated considerable interest in the field of computer vision because of its wide spectrum of potential applications. Human behavior can be segmented into atomic actions, each of which indicates a basic and complete movement. Learning and recognizing atomic human actions are essential to human behavior analysis. In this paper, we propose a framework for handling this task using variable-length Markov models (VLMMs). The framework is comprised of the following two modules: a posture labeling module and a VLMM atomic action learning and recognition module. First, a posture template selection algorithm, based on a modified shape context matching technique, is developed. The selected posture templates form a codebook that is used to convert input posture sequences into discrete symbol sequences for subsequent processing. Then, the VLMM technique is applied to learn the training symbol sequences of atomic actions. Finally, the constructed VLMMs are transformed into hidden Markov models (HMMs) for recognizing input atomic actions. This approach combines the advantages of the excellent learning function of a VLMM and the fault-tolerant recognition ability of an HMM. Experiments on realistic data demonstrate the efficacy of the proposed system.

  2. A probability space for quantum models

    Science.gov (United States)

    Lemmens, L. F.

    2017-06-01

    A probability space contains a set of outcomes, a collection of events formed by subsets of the set of outcomes and probabilities defined for all events. A reformulation in terms of propositions allows to use the maximum entropy method to assign the probabilities taking some constraints into account. The construction of a probability space for quantum models is determined by the choice of propositions, choosing the constraints and making the probability assignment by the maximum entropy method. This approach shows, how typical quantum distributions such as Maxwell-Boltzmann, Fermi-Dirac and Bose-Einstein are partly related with well-known classical distributions. The relation between the conditional probability density, given some averages as constraints and the appropriate ensemble is elucidated.

  3. Perception-action learning as an epistemologically-consistent model for self-updating cognitive representation.

    Science.gov (United States)

    Windridge, David; Kittler, Josef

    2010-01-01

    As well as having the ability to formulate models of the world capable of experimental falsification, it is evident that human cognitive capability embraces some degree of representational plasticity, having the scope (at least in infancy) to modify the primitives in terms of which the world is delineated. We hence employ the term 'cognitive bootstrapping' to refer to the autonomous updating of an embodied agent's perceptual framework in response to the perceived requirements of the environment in such a way as to retain the ability to refine the environment model in a consistent fashion across perceptual changes.We will thus argue that the concept of cognitive bootstrapping is epistemically ill-founded unless there exists an a priori percept/motor interrelation capable of maintaining an empirical distinction between the various possibilities of perceptual categorization and the inherent uncertainties of environment modeling.As an instantiation of this idea, we shall specify a very general, logically-inductive model of perception-action learning capable of compact re-parameterization of the percept space. In consequence of the a priori percept/action coupling, the novel perceptual state transitions so generated always exist in bijective correlation with a set of novel action states, giving rise to the required empirical validation criterion for perceptual inferences. Environmental description is correspondingly accomplished in terms of progressively higher-level affordance conjectures which are likewise validated by exploratory action.Application of this mechanism within simulated perception-action environments indicates that, as well as significantly reducing the size and specificity of the a priori perceptual parameter-space, the method can significantly reduce the number of iterations required for accurate convergence of the world-model. It does so by virtue of the active learning characteristics implicit in the notion of cognitive bootstrapping.

  4. Integrated Space Asset Management Database and Modeling

    Science.gov (United States)

    MacLeod, Todd; Gagliano, Larry; Percy, Thomas; Mason, Shane

    2015-01-01

    Effective Space Asset Management is one key to addressing the ever-growing issue of space congestion. It is imperative that agencies around the world have access to data regarding the numerous active assets and pieces of space junk currently tracked in orbit around the Earth. At the center of this issues is the effective management of data of many types related to orbiting objects. As the population of tracked objects grows, so too should the data management structure used to catalog technical specifications, orbital information, and metadata related to those populations. Marshall Space Flight Center's Space Asset Management Database (SAM-D) was implemented in order to effectively catalog a broad set of data related to known objects in space by ingesting information from a variety of database and processing that data into useful technical information. Using the universal NORAD number as a unique identifier, the SAM-D processes two-line element data into orbital characteristics and cross-references this technical data with metadata related to functional status, country of ownership, and application category. The SAM-D began as an Excel spreadsheet and was later upgraded to an Access database. While SAM-D performs its task very well, it is limited by its current platform and is not available outside of the local user base. Further, while modeling and simulation can be powerful tools to exploit the information contained in SAM-D, the current system does not allow proper integration options for combining the data with both legacy and new M&S tools. This paper provides a summary of SAM-D development efforts to date and outlines a proposed data management infrastructure that extends SAM-D to support the larger data sets to be generated. A service-oriented architecture model using an information sharing platform named SIMON will allow it to easily expand to incorporate new capabilities, including advanced analytics, M&S tools, fusion techniques and user interface for

  5. String states, loops and effective actions in noncommutative field theory and matrix models

    Directory of Open Access Journals (Sweden)

    Harold C. Steinacker

    2016-09-01

    Full Text Available Refining previous work by Iso, Kawai and Kitazawa, we discuss bi-local string states as a tool for loop computations in noncommutative field theory and matrix models. Defined in terms of coherent states, they exhibit the stringy features of noncommutative field theory. This leads to a closed form for the 1-loop effective action in position space, capturing the long-range non-local UV/IR mixing for scalar fields. The formalism applies to generic fuzzy spaces. The non-locality is tamed in the maximally supersymmetric IKKT or IIB model, where it gives rise to supergravity. The linearized supergravity interactions are obtained directly in position space at one loop using string states on generic noncommutative branes.

  6. String states, loops and effective actions in noncommutative field theory and matrix models

    Energy Technology Data Exchange (ETDEWEB)

    Steinacker, Harold C., E-mail: harold.steinacker@univie.ac.at

    2016-09-15

    Refining previous work by Iso, Kawai and Kitazawa, we discuss bi-local string states as a tool for loop computations in noncommutative field theory and matrix models. Defined in terms of coherent states, they exhibit the stringy features of noncommutative field theory. This leads to a closed form for the 1-loop effective action in position space, capturing the long-range non-local UV/IR mixing for scalar fields. The formalism applies to generic fuzzy spaces. The non-locality is tamed in the maximally supersymmetric IKKT or IIB model, where it gives rise to supergravity. The linearized supergravity interactions are obtained directly in position space at one loop using string states on generic noncommutative branes.

  7. Cognitive engineering models in space systems

    Science.gov (United States)

    Mitchell, Christine M.

    1993-01-01

    NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab

  8. Numerical modelling of elastic space tethers

    DEFF Research Database (Denmark)

    Kristiansen, Kristian Uldall; Palmer, P. L.; Roberts, R. M.

    2012-01-01

    In this paper the importance of the ill-posedness of the classical, non-dissipative massive tether model on an orbiting tether system is studied numerically. The computations document that via the regularisation of bending resistance a more reliable numerical integrator can be produced. Furthermore......, the numerical experiments of an orbiting tether system show that bending may introduce significant forces in some regions of phase space. Finally, numerical evidence for the existence of an almost invariant slow manifold of the singularly perturbed, regularised, non-dissipative massive tether model is provided....... It is also shown that on the slow manifold the dynamics of the satellites are well-approximated by the finite dimensional slack-spring model....

  9. Joint action of pharmaceuticals in model lipid membranes: calorimetric effects

    Directory of Open Access Journals (Sweden)

    О. В. Ващенко

    2016-11-01

    Full Text Available Joint action of a number of pharmaceuticals has been studied in multibilayer model membranes of L-α-dipalmitoylphosphatidylcholine. Shift of the main phase transition temperature of the membrane under the pharmaceuticals introduction (∆Tm was determined by means of differential scanning calorimetry and used as a basic factor of their membranotropic action (MA. Pairs of pharmaceuticals were selected with various character of lipophylicity and MA; cholesterol was used as the membrane compound with the well-known MA. Revelation and identification of the effects of joint action was performed by comparison of ∆Tm values under separate and joint introduction of the pharmaceuticals. Effects of joint action appear similar for hydrophobic azithromycin and hydrophilic succinylcholine in their combinations both with povidone and with cholesterol. Examination of joint action of an active pharmaceutical intgredient (API and and an excipient allowed us to establish a certain advantage of the API’s MA in the pairs azithromycin-lactose and azithromycin-dimetylsulfoxide, and additivity of the MA in the pair amixin-hypromelose.

  10. Integrated Space Asset Management Database and Modeling

    Science.gov (United States)

    Gagliano, L.; MacLeod, T.; Mason, S.; Percy, T.; Prescott, J.

    The Space Asset Management Database (SAM-D) was implemented in order to effectively track known objects in space by ingesting information from a variety of databases and performing calculations to determine the expected position of the object at a specified time. While SAM-D performs this task very well, it is limited by technology and is not available outside of the local user base. Modeling and simulation can be powerful tools to exploit the information contained in SAM-D. However, the current system does not allow proper integration options for combining the data with both legacy and new M&S tools. A more capable data management infrastructure would extend SAM-D to support the larger data sets to be generated by the COI. A service-oriented architecture model will allow it to easily expand to incorporate new capabilities, including advanced analytics, M&S tools, fusion techniques and user interface for visualizations. Based on a web-centric approach, the entire COI will be able to access the data and related analytics. In addition, tight control of information sharing policy will increase confidence in the system, which would encourage industry partners to provide commercial data. SIMON is a Government off the Shelf information sharing platform in use throughout DoD and DHS information sharing and situation awareness communities. SIMON providing fine grained control to data owners allowing them to determine exactly how and when their data is shared. SIMON supports a micro-service approach to system development, meaning M&S and analytic services can be easily built or adapted. It is uniquely positioned to fill this need as an information-sharing platform with a proven track record of successful situational awareness system deployments. Combined with the integration of new and legacy M&S tools, a SIMON-based architecture will provide a robust SA environment for the NASA SA COI that can be extended and expanded indefinitely. First Results of Coherent Uplink from a

  11. A probabilistic model of RNA conformational space

    DEFF Research Database (Denmark)

    Frellsen, Jes; Moltke, Ida; Thiim, Martin

    2009-01-01

    The increasing importance of non-coding RNA in biology and medicine has led to a growing interest in the problem of RNA 3-D structure prediction. As is the case for proteins, RNA 3-D structure prediction methods require two key ingredients: an accurate energy function and a conformational sampling...... procedure. Both are only partly solved problems. Here, we focus on the problem of conformational sampling. The current state of the art solution is based on fragment assembly methods, which construct plausible conformations by stringing together short fragments obtained from experimental structures. However...... efficient sampling of RNA conformations in continuous space, and with associated probabilities. We show that the model captures several key features of RNA structure, such as its rotameric nature and the distribution of the helix lengths. Furthermore, the model readily generates native-like 3-D...

  12. Being present in action: a theoretical model about the interlocking between intentions and environmental affordances

    Directory of Open Access Journals (Sweden)

    Stefano eTriberti

    2016-01-01

    Full Text Available Recent neuropsychological evidence suggest that a key role in linking perceptions and intentions is played by sense of presence. Despite this phenomenon having been studied primarily in the field of virtual reality (conceived as the illusion of being in the virtual space, recent research highlighted that it is a fundamental feature of everyday experience. Specifically, the function of presence as a cognitive process is to locate the Self in a physical space or situation, based on the perceived possibility to act in it; so, the variations in sense of presence allow one to continuously adapt his own action to the external environment. Indeed intentions, as the cognitive antecedents of action, are not static representations of the desired outcomes, but dynamic processes able to adjust their own representational content according to the opportunities/restrictions emerging in the environment. Focusing on the peculiar context of action mediated by interactive technologies, we here propose a theoretical model showing how each level of an intentional hierarchy (future-directed; present directed; and motor intentions can interlock with environmental affordances in order to promote a continuous stream of action and activity.

  13. Modeling human-flood interactions: Collective action and community resilience.

    Science.gov (United States)

    Yu, D. J.; Sangwan, N.; Sung, K.

    2016-12-01

    Stylized models of socio-hydrology have mainly used social memory aspects such as community awareness or sensitivity to connect hydrologic change and social response. However, social memory alone does not satisfactorily capture the details of how human behavior is translated into collective action for water resources governance. Nor is it the only mechanism by which the two-way feedbacks of socio-hydrology can be operationalized. This study contributes towards bridging of this gap by developing a stylized model of a human-flood system that includes two additional drivers of change: (1) institutions for collective action, and (2) connections to an external economic system. Motivated by the case of community-managed flood protection systems (polders) in coastal Bangladesh, we use the model to understand critical general features that affect long-term resilience of human-flood systems. Our findings suggest that occasional adversity can enhance long-term resilience. Allowing some hydrological variability to enter into the polder can increase its adaptive capacity and resilience through the preservation of social memory and institutions for collective action. Further, there are potential tradeoffs associated with optimization of flood resilience through structural measures. By reducing sensitivity to flooding, the system may become more fragile under the double impact of flooding and economic change

  14. Action direction of muscle synergies in three-dimensional force space

    Directory of Open Access Journals (Sweden)

    Shota eHagio

    2015-11-01

    Full Text Available Redundancy in the musculoskeletal system was supposed to be simplified by muscle synergies, which modularly organize muscles. To clarify the underlying mechanisms of motor control using muscle synergies, it is important to examine the spatiotemporal contribution of muscle synergies in the task space. In this study, we quantified the mechanical contribution of muscle synergies as considering spatiotemporal correlation between the activation of muscle synergies and endpoint force fluctuations. Subjects performed isometric force generation in the 3-dimensional force space. The muscle-weighting vectors of muscle synergies and their activation traces across different trials were extracted from EMG data using decomposing technique. We then estimated mechanical contribution of muscle synergies across each trial based on cross-correlation analysis. The contributing vectors were averaged for all trials and the averaging was defined as action direction (AD of muscle synergies. As a result, we extracted approximately 5 muscle synergies. The ADs of muscle synergies mainly depended on the anatomical functions of their weighting muscles. Furthermore, the AD of each muscle indicated the synchronous activation of muscles, which composed the same muscle synergy. These results provide the spatiotemporal characteristics of muscle synergies as neural basis.

  15. Re-modeling Chara action potential: II. The action potential form under salinity stress

    Directory of Open Access Journals (Sweden)

    Mary Jane Beilby

    2017-04-01

    Full Text Available In part I we established Thiel-Beilby model of the Chara action potential (AP. In part II the AP is investigated in detail at the time of saline stress. Even very short exposure of salt-sensitive Chara cells to artificial pond water with 50 mM NaCl (Saline APW modified the AP threshold and drastically altered the AP form. Detailed modeling of 14 saline APs from 3 cells established that both the Ca2+ pump and the Ca2+ channels on internal stores seem to be affected, with the changes sometimes cancelling and sometimes re-enforcing each other, leading to APs with long durations and very complex forms. The exposure to salinity offers further insights into AP mechanism and suggests future experiments. The prolonged APs lead to greater loss of chloride and potassium ions, compounding the effects of saline stress.

  16. Space market model development project, phase 2

    Science.gov (United States)

    Bishop, Peter C.

    1988-01-01

    The results of the prototype operations of the Space Business Information Center are presented. A clearinghouse for space business information for members of the U.S. space industry composed of public, private, and academic sectors was conducted. Behavioral and evaluation statistics were recorded from the clearinghouse and the conclusions from these statistics are presented. Business guidebooks on major markets in space business are discussed. Proprietary research and briefings for firms and agencies in the space industry are also discussed.

  17. Propagation of signals in spaces with affine connections and metrics as models of space-time

    OpenAIRE

    Manoff, Sawa

    2003-01-01

    The propagation of signals in space-time is considered on the basis of the notion of null (isotropic) vector field in spaces with affine connections and metrics as models of space or of space-time. The Doppler effect is generalized for these types of spaces. The notions of aberration, standard (longitudinal) Doppler effect, and transversal Doppler effect are considered. On their grounds, the Hubble effect appears as Doppler effect with explicit forms of the centrifugal (centripetal) and Corio...

  18. A Social Identity Model of Pro-Environmental Action (SIMPEA).

    Science.gov (United States)

    Fritsche, Immo; Barth, Markus; Jugert, Philipp; Masson, Torsten; Reese, Gerhard

    2017-12-21

    Large-scale environmental crises are genuinely collective phenomena: they usually result from collective, rather than personal, behavior and how they are cognitively represented and appraised is determined by collectively shared interpretations (e.g., differing across ideological groups) and based on concern for collectives (e.g., humankind, future generations) rather than for individuals. Nevertheless, pro-environmental action has been primarily investigated as a personal decision-making process. We complement this research with a social identity perspective on pro-environmental action. Social identity is the human capacity to define the self in terms of "We" instead of "I," enabling people to think and act as collectives, which should be crucial given personal insufficiency to appraise and effectively respond to environmental crises. We propose a Social Identity Model of Pro-Environmental Action (SIMPEA) of how social identity processes affect both appraisal of and behavioral responses to large-scale environmental crises. We review related and pertinent research providing initial evidence for the role of 4 social identity processes hypothesized in SIMPEA. Specifically, we propose that ingroup identification, ingroup norms and goals, and collective efficacy determine environmental appraisals as well as both private and public sphere environmental action. These processes are driven by personal and collective emotions and motivations that arise from environmental appraisal and operate on both a deliberate and automatic processing level. Finally, we discuss SIMPEA's implications for the research agenda in environmental and social psychology and for interventions fostering pro-environmental action. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Space Weather Products at the Community Coordinated Modeling Center

    Science.gov (United States)

    Hesse, Michael; Kuznetsova, M.; Pulkkinen, A.; Maddox, M.; Rastaetter, L.; Berrios, D.; MacNeice, P.

    2010-01-01

    The Community Coordinated Modeling Center (CCMC) is a US inter-agency activity aiming at research in support of the generation of advanced space weather models. As one of its main functions, the CCMC provides to researchers the use of space science models, even if they are not model owners themselves. The second CCMC activity is to support Space Weather forecasting at national Space Weather Forecasting Centers. This second activity involves model evaluations, model transitions to operations, and the development of space weather forecasting tools. Owing to the pace of development in the science community, new model capabilities emerge frequently. Consequently, space weather products and tools involve not only increased validity, but often entirely new capabilities. This presentation will review the present state of space weather tools as well as point out emerging future capabilities.

  20. Effective action model of dynamically scalarizing binary neutron stars

    Science.gov (United States)

    Sennett, Noah; Shao, Lijing; Steinhoff, Jan

    2017-10-01

    Gravitational waves can be used to test general relativity (GR) in the highly dynamical strong-field regime. Scalar-tensor theories of gravity are natural alternatives to GR that can manifest nonperturbative phenomena in neutron stars (NSs). One such phenomenon, known as dynamical scalarization, occurs in coalescing binary NS systems. Ground-based gravitational-wave detectors may be sensitive to this effect, and thus could potentially further constrain scalar-tensor theories. This type of analysis requires waveform models of dynamically scalarizing systems; in this work we devise an analytic model of dynamical scalarization using an effective action approach. For the first time, we compute the Newtonian-order Hamiltonian describing the dynamics of a dynamically scalarizing binary in a self-consistent manner. Despite only working to leading order, the model accurately predicts the frequency at which dynamical scalarization occurs. In conjunction with Landau theory, our model allows one to definitively establish dynamical scalarization as a second-order phase transition. We also connect dynamical scalarization to the related phenomena of spontaneous scalarization and induced scalarization; these phenomena are naturally encompassed into our effective action approach.

  1. Globalisation and health inequalities: can a human rights paradigm create space for civil society action?

    Science.gov (United States)

    London, Leslie; Schneider, Helen

    2012-01-01

    While neoliberal globalisation is associated with increasing inequalities, global integration has simultaneously strengthened the dissemination of human rights discourse across the world. This paper explores the seeming contradiction that globalisation is conceived as disempowering nations states' ability to act in their population's interests, yet implementation of human rights obligations requires effective states to deliver socio-economic entitlements, such as health. Central to the actions required of the state to build a health system based on a human rights approach is the notion of accountability. Two case studies are used to explore the constraints on states meeting their human rights obligations regarding health, the first drawing on data from interviews with parliamentarians responsible for health in East and Southern Africa, and the second reflecting on the response to the HIV/AIDS epidemic in South Africa. The case studies illustrate the importance of a human rights paradigm in strengthening parliamentary oversight over the executive in ways that prioritise pro-poor protections and in increasing leverage for resources for the health sector within parliamentary processes. Further, a rights framework creates the space for civil society action to engage with the legislature to hold public officials accountable and confirms the importance of rights as enabling civil society mobilization, reinforcing community agency to advance health rights for poor communities. In this context, critical assessment of state incapacity to meet claims to health rights raises questions as to the diffusion of accountability rife under modern international aid systems. Such diffusion of accountability opens the door to 'cunning' states to deflect rights claims of their populations. We argue that human rights, as both a normative framework for legal challenges and as a means to create room for active civil society engagement provide a means to contest both the real and the

  2. Linking knowledge and action through mental models of sustainable agriculture.

    Science.gov (United States)

    Hoffman, Matthew; Lubell, Mark; Hillis, Vicken

    2014-09-09

    Linking knowledge to action requires understanding how decision-makers conceptualize sustainability. This paper empirically analyzes farmer "mental models" of sustainability from three winegrape-growing regions of California where local extension programs have focused on sustainable agriculture. The mental models are represented as networks where sustainability concepts are nodes, and links are established when a farmer mentions two concepts in their stated definition of sustainability. The results suggest that winegrape grower mental models of sustainability are hierarchically structured, relatively similar across regions, and strongly linked to participation in extension programs and adoption of sustainable farm practices. We discuss the implications of our findings for the debate over the meaning of sustainability, and the role of local extension programs in managing knowledge systems.

  3. Action of ozonized water in preclinical inflammatory models.

    Science.gov (United States)

    Cardoso, C C; Carvalho, J C; Ovando, E C; Macedo, S B; Dall'Aglio, R; Ferreira, L R

    2000-07-01

    Ozonized water increases oxygen local tension. The ozone by itself produces inflammatory reactions in lung epithelium. The action of ozonized water during the inflammatory process was investigated. In rat paw edema induced by carrageenin, the inflammatory process was stimulated by ozonized water (1.2 microg, p.o.) when applied 30 min prior to the induction. In the inflammatory process induced by Freund's Complete Adjuvant, the ozonized water did not interfere in the inflammatory reaction. Furthermore, in gastric ulcers models induced by stress, there was a significant reduction in the incidence of ulcers types I, II and III (P<0.05, Student's t -test). Copyright 2000 Academic Press.

  4. Gauging N=2 supersymmetric non-linear {sigma}-models in the Atiyah-Ward space-time

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, M.; Oliveira, M.W. de [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)

    1996-11-01

    It was built up a class of N=2 supersymmetric non-linear {sigma}-models in an N=1 superspace based on the Atiyah-Ward space-time of (2+2)-signature metric. Is also discussed the gauging of isometries of the associated hyper-Kaehlerian target spaces and present the resulting gauge-covariant supersymmetric action functional. (author). 27 refs.

  5. Continuous Human Action Recognition Using Depth-MHI-HOG and a Spotter Model

    Science.gov (United States)

    Eum, Hyukmin; Yoon, Changyong; Lee, Heejin; Park, Mignon

    2015-01-01

    In this paper, we propose a new method for spotting and recognizing continuous human actions using a vision sensor. The method is comprised of depth-MHI-HOG (DMH), action modeling, action spotting, and recognition. First, to effectively separate the foreground from background, we propose a method called DMH. It includes a standard structure for segmenting images and extracting features by using depth information, MHI, and HOG. Second, action modeling is performed to model various actions using extracted features. The modeling of actions is performed by creating sequences of actions through k-means clustering; these sequences constitute HMM input. Third, a method of action spotting is proposed to filter meaningless actions from continuous actions and to identify precise start and end points of actions. By employing the spotter model, the proposed method improves action recognition performance. Finally, the proposed method recognizes actions based on start and end points. We evaluate recognition performance by employing the proposed method to obtain and compare probabilities by applying input sequences in action models and the spotter model. Through various experiments, we demonstrate that the proposed method is efficient for recognizing continuous human actions in real environments. PMID:25742172

  6. Continuous Human Action Recognition Using Depth-MHI-HOG and a Spotter Model

    Directory of Open Access Journals (Sweden)

    Hyukmin Eum

    2015-03-01

    Full Text Available In this paper, we propose a new method for spotting and recognizing continuous human actions using a vision sensor. The method is comprised of depth-MHI-HOG (DMH, action modeling, action spotting, and recognition. First, to effectively separate the foreground from background, we propose a method called DMH. It includes a standard structure for segmenting images and extracting features by using depth information, MHI, and HOG. Second, action modeling is performed to model various actions using extracted features. The modeling of actions is performed by creating sequences of actions through k-means clustering; these sequences constitute HMM input. Third, a method of action spotting is proposed to filter meaningless actions from continuous actions and to identify precise start and end points of actions. By employing the spotter model, the proposed method improves action recognition performance. Finally, the proposed method recognizes actions based on start and end points. We evaluate recognition performance by employing the proposed method to obtain and compare probabilities by applying input sequences in action models and the spotter model. Through various experiments, we demonstrate that the proposed method is efficient for recognizing continuous human actions in real environments.

  7. Spectral action for Bianchi type-IX cosmological models

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Wentao; Fathizadeh, Farzad; Marcolli, Matilde [Division of Physics, Mathematics and Astronomy, California Institute of Technology,1200 E. California Blvd., Pasadena, CA 91125 (United States)

    2015-10-13

    A rationality result previously proved for Robertson-Walker metrics is extended to a homogeneous anisotropic cosmological model, namely the Bianchi type-IX minisuperspace. It is shown that the Seeley-de Witt coefficients appearing in the expansion of the spectral action for the Bianchi type-IX geometry are expressed in terms of polynomials with rational coefficients in the cosmic evolution factors w{sub 1}(t),w{sub 2}(t),w{sub 3}(t), and their higher derivates with respect to time. We begin with the computation of the Dirac operator of this geometry and calculate the coefficients a{sub 0},a{sub 2},a{sub 4} of the spectral action by using heat kernel methods and parametric pseudodifferential calculus. An efficient method is devised for computing the Seeley-de Witt coefficients of a geometry by making use of Wodzicki’s noncommutative residue, and it is confirmed that the method checks out for the cosmological model studied in this article. The advantages of the new method are discussed, which combined with symmetries of the Bianchi type-IX metric, yield an elegant proof of the rationality result.

  8. Sigma model renormalization group flow, ``central charge'' action, and Perelman's entropy

    Science.gov (United States)

    Tseytlin, A. A.

    2007-03-01

    Zamolodchikov’s c-theorem type argument (and also string theory effective action constructions) imply that the RG flow in 2d sigma model should be a gradient one to all loop orders. However, the monotonicity of the flow of the target-space metric is not obvious since the metric on the space of metric-dilaton couplings is indefinite. To leading (one-loop) order when the RG flow is simply the Ricci flow the monotonicity was proved by Perelman [G. Perelman, math.dg/0211159.] by constructing an “entropy” functional which is essentially the metric-dilaton action extremized with respect to the dilaton with a condition that the target-space volume is fixed. We discuss how to generalize the Perelman’s construction to all loop orders (i.e. all orders in α'). The resulting entropy is equal to minus the central charge at the fixed points, in agreement with the general claim of the c-theorem.

  9. THE USE OF MODELS IN URBAN SPACE PATTERN ANALYSIS ...

    African Journals Online (AJOL)

    THE USE OF MODELS IN URBAN SPACE PATTERN ANALYSIS. Wubshet Berhanu. Department of Architecture and Urban Planning. Addis Ababa University. ABSTRACT. This paper focuses 011 the use of urban space pattern analysis methods. Physical developmems once located in space influence a set of social and.

  10. Spaces for the Social Shaping of Information Technology and Work. A reassessment of Scandinavian action research and its implications for action

    DEFF Research Database (Denmark)

    Clausen, Christian

    2004-01-01

    30 years. The paper provides an overview of Scandinavian research within technology and working life form a Danish perspective. A major contribution is con-cerned with a variety of strategies employed by social actors involved in action research pro-jects and their role in the social shaping......This contribution explores a range of social spaces where unions and workers have played or potential can play a role in the local social shaping of IT and work. It will mainly be based on the authors own research and experiences within Scandinavian research on technology and working from the past...... of technology. The point is made that no single strat-egy have proved to provide an uncontested route for union or workers influence. Instead the Scandinavian experiences indicate, that a range of spaces, players and positions have been developed, providing opportunities for addressing questions related...

  11. Physical simulation of the long-term dynamic action of a plasma beam on a space debris object

    Science.gov (United States)

    Shuvalov, Valentin A.; Gorev, Nikolai. B.; Tokmak, Nikolai A.; Kochubei, Galina S.

    2017-03-01

    A methodology is developed for physical (laboratory) simulation of the long-term dynamic action of plasma beam high-energy ions on a space debris object with the aim of removing it to a lower orbit followed by its burning in the Earth's atmosphere. The methodology is based on the use of a criterion for the equivalence of two plasma beam exposure regimes (in the Earth' ionosphere and in laboratory conditions) and an accelerated test procedure in what concerns space debris object material sputtering and space debris object erosion by a plasma beam in the Earth's ionosphere. The space debris coating material (blanket thermal insulation) sputtering yield and normal and tangential momentum transfer coefficients are determined experimentally as a function of the ion energy and the ion beam incidence angle.

  12. A consistent model for tsunami actions on buildings

    Science.gov (United States)

    Foster, A.; Rossetto, T.; Eames, I.; Chandler, I.; Allsop, W.

    2016-12-01

    The Japan (2011) and Indian Ocean (2004) tsunami resulted in significant loss of life, buildings, and critical infrastructure. The tsunami forces imposed upon structures in coastal regions are initially due to wave slamming, after which the quasi-steady flow of the sea water around buildings becomes important. An essential requirement in both design and loss assessment is a consistent model that can accurately predict these forces. A model suitable for predicting forces in the in the quasi-steady range has been established as part of a systematic programme of research by the UCL EPICentre to understand the fundamental physical processes of tsunami actions on buildings, and more generally their social and economic consequences. Using the pioneering tsunami generator at HR Wallingford, this study considers the influence of unsteady flow conditions on the forces acting upon a rectangular building occupying 10-80% of a channel for 20-240 second wave periods. A mathematical model based upon basic open-channel flow principles is proposed, which provides empirical estimates for drag and hydrostatic coefficients. A simple force prediction equation, requiring only basic flow velocity and wave height inputs is then developed, providing good agreement with the experimental results. The results of this study demonstrate that the unsteady forces from the very long waves encountered during tsunami events can be predicted with a level of accuracy and simplicity suitable for design and risk assessment.

  13. Vector space model for document representation in information retrieval

    Directory of Open Access Journals (Sweden)

    Dan MUNTEANU

    2007-12-01

    Full Text Available This paper presents the basics of information retrieval: the vector space model for document representation with Boolean and term weighted models, ranking methods based on the cosine factor and evaluation measures: recall, precision and combined measure.

  14. Mixed Models: Combining incompatible scalar models in any space-time dimension

    Science.gov (United States)

    Klauder, John R.

    2017-01-01

    Traditionally, covariant scalar field theory models are either super renormalizable, strictly renormalizable, or nonrenormalizable. The goal of “Mixed Models” is to make sense of sums of these distinct examples, e.g. gφ34 + g‧φ 36 + g″φ 38, which includes an example of each kind for space-time dimension n = 3. We show how the several interactions such mixed models have may be turned on and off in any order without any difficulties. Analogous results are shown for gφn4 + g‧φ n138, etc. for all n ≥ 3. Different categories hold for n = 2 such as, e.g. gP(φ)2 + g‧NP(φ) 2, that involve polynomial (P) and suitable nonpolynomial (NP) interactions, etc. Analogous situations for n = 1 (time alone) offer simple “toy” examples of how such mixed models may be constructed. As a general rule, if the introduction of a specific interaction term reduces the domain of the free classical action, we invariably find that the introduction of the associated quantum interaction leads, effectively, to a “nonrenormalizable” quantum theory. However, in special cases, a classical interaction that does not reduce the domain of the classical free action may generate an “unsatisfactory” quantum theory, which generally involves a model-specific, different approach to become “satisfactory.” We will encounter both situations in our analysis.

  15. Standardization Process for Space Radiation Models Used for Space System Design

    Science.gov (United States)

    Barth, Janet; Daly, Eamonn; Brautigam, Donald

    2005-01-01

    The space system design community has three concerns related to models of the radiation belts and plasma: 1) AP-8 and AE-8 models are not adequate for modern applications; 2) Data that have become available since the creation of AP-8 and AE-8 are not being fully exploited for modeling purposes; 3) When new models are produced, there is no authorizing organization identified to evaluate the models or their datasets for accuracy and robustness. This viewgraph presentation provided an overview of the roadmap adopted by the Working Group Meeting on New Standard Radiation Belt and Space Plasma Models.

  16. Browsing Space Weather Data and Models with the Integrated Space Weather Analysis (iSWA) System

    Science.gov (United States)

    Maddox, Marlo M.; Mullinix, Richard E.; Berrios, David H.; Hesse, Michael; Rastaetter, Lutz; Pulkkinen, Antti; Hourcle, Joseph A.; Thompson, Barbara J.

    2011-01-01

    The Integrated Space Weather Analysis (iSWA) System is a comprehensive web-based platform for space weather information that combines data from solar, heliospheric and geospace observatories with forecasts based on the most advanced space weather models. The iSWA system collects, generates, and presents a wide array of space weather resources in an intuitive, user-configurable, and adaptable format - thus enabling users to respond to current and future space weather impacts as well as enabling post-impact analysis. iSWA currently provides over 200 data and modeling products, and features a variety of tools that allow the user to browse, combine, and examine data and models from various sources. This presentation will consist of a summary of the iSWA products and an overview of the customizable user interfaces, and will feature several tutorial demonstrations highlighting the interactive tools and advanced capabilities.

  17. Population of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisation.

    Science.gov (United States)

    Gemmell, Philip; Burrage, Kevin; Rodriguez, Blanca; Quinn, T Alexander

    2014-01-01

    Variability is observed at all levels of cardiac electrophysiology. Yet, the underlying causes and importance of this variability are generally unknown, and difficult to investigate with current experimental techniques. The aim of the present study was to generate populations of computational ventricular action potential models that reproduce experimentally observed intercellular variability of repolarisation (represented by action potential duration) and to identify its potential causes. A systematic exploration of the effects of simultaneously varying the magnitude of six transmembrane current conductances (transient outward, rapid and slow delayed rectifier K(+), inward rectifying K(+), L-type Ca(2+), and Na(+)/K(+) pump currents) in two rabbit-specific ventricular action potential models (Shannon et al. and Mahajan et al.) at multiple cycle lengths (400, 600, 1,000 ms) was performed. This was accomplished with distributed computing software specialised for multi-dimensional parameter sweeps and grid execution. An initial population of 15,625 parameter sets was generated for both models at each cycle length. Action potential durations of these populations were compared to experimentally derived ranges for rabbit ventricular myocytes. 1,352 parameter sets for the Shannon model and 779 parameter sets for the Mahajan model yielded action potential duration within the experimental range, demonstrating that a wide array of ionic conductance values can be used to simulate a physiological rabbit ventricular action potential. Furthermore, by using clutter-based dimension reordering, a technique that allows visualisation of multi-dimensional spaces in two dimensions, the interaction of current conductances and their relative importance to the ventricular action potential at different cycle lengths were revealed. Overall, this work represents an important step towards a better understanding of the role that variability in current conductances may play in experimentally

  18. Generalized iterative annealing model for the action of RNA chaperones

    Science.gov (United States)

    Hyeon, Changbong; Thirumalai, D.

    2013-09-01

    As a consequence of the rugged landscape of RNA molecules their folding is described by the kinetic partitioning mechanism according to which only a small fraction (ϕF) reaches the folded state while the remaining fraction of molecules is kinetically trapped in misfolded intermediates. The transition from the misfolded states to the native state can far exceed biologically relevant time. Thus, RNA folding in vivo is often aided by protein cofactors, called RNA chaperones, that can rescue RNAs from a multitude of misfolded structures. We consider two models, based on chemical kinetics and chemical master equation, for describing assisted folding. In the passive model, applicable for class I substrates, transient interactions of misfolded structures with RNA chaperones alone are sufficient to destabilize the misfolded structures, thus entropically lowering the barrier to folding. For this mechanism to be efficient the intermediate ribonucleoprotein complex between collapsed RNA and protein cofactor should have optimal stability. We also introduce an active model (suitable for stringent substrates with small ϕF), which accounts for the recent experimental findings on the action of CYT-19 on the group I intron ribozyme, showing that RNA chaperones do not discriminate between the misfolded and the native states. In the active model, the RNA chaperone system utilizes chemical energy of adenosine triphosphate hydrolysis to repeatedly bind and release misfolded and folded RNAs, resulting in substantial increase of yield of the native state. The theory outlined here shows, in accord with experiments, that in the steady state the native state does not form with unit probability.

  19. Phase transitions in lattice 2D O(N) sigma-model with mixed action in the large N limit

    Energy Technology Data Exchange (ETDEWEB)

    Magnoli, N.; Ravanini, F.

    1987-03-01

    We study the exact N->infinity solution of the two-dimensional lattice o(N) sigma-model, described by a two parameter action that mixes Wilson (quadratic) and RP/sup N-1/proportional to O(N)/Z/sub 2/ (quartic) actions. A rich phase structure emerges, with a first order transition line crossing, in the two-dimensional parameter space the RP/sup N-1/ axis. At the end of this line the specific-heat diverges while the correlation length remains finite.

  20. Optimization using surrogate models - by the space mapping technique

    DEFF Research Database (Denmark)

    Søndergaard, Jacob

    2003-01-01

    Surrogate modelling and optimization techniques are intended for engineering design in the case where an expensive physical model is involved. This thesis provides a literature overview of the field of surrogate modelling and optimization. The space mapping technique is one such method for constr......Surrogate modelling and optimization techniques are intended for engineering design in the case where an expensive physical model is involved. This thesis provides a literature overview of the field of surrogate modelling and optimization. The space mapping technique is one such method...... conditions are satisfied. So hybrid methods, combining the space mapping technique with classical optimization methods, should be used if convergence to high accuracy is wanted. Approximation abilities of the space mapping surrogate are compared with those of a Taylor model of the expensive model. The space...... mapping surrogate has a lower approximation error for long steps. For short steps, however, the Taylor model of the expensive model is best, due to exact interpolation at the model origin. Five algorithms for space mapping optimization are presented and the numerical performance is evaluated. Three...

  1. KFAS: Exponential Family State Space Models in R

    Directory of Open Access Journals (Sweden)

    Jouni Helske

    2017-06-01

    Full Text Available State space modeling is an efficient and flexible method for statistical inference of a broad class of time series and other data. This paper describes the R package KFAS for state space modeling with the observations from an exponential family, namely Gaussian, Poisson, binomial, negative binomial and gamma distributions. After introducing the basic theory behind Gaussian and non-Gaussian state space models, an illustrative example of Poisson time series forecasting is provided. Finally, a comparison to alternative R packages suitable for non-Gaussian time series modeling is presented.

  2. Partial differential equations in action from modelling to theory

    CERN Document Server

    Salsa, Sandro

    2016-01-01

    The book is intended as an advanced undergraduate or first-year graduate course for students from various disciplines, including applied mathematics, physics and engineering. It has evolved from courses offered on partial differential equations (PDEs) over the last several years at the Politecnico di Milano. These courses had a twofold purpose: on the one hand, to teach students to appreciate the interplay between theory and modeling in problems arising in the applied sciences, and on the other to provide them with a solid theoretical background in numerical methods, such as finite elements. Accordingly, this textbook is divided into two parts. The first part, chapters 2 to 5, is more elementary in nature and focuses on developing and studying basic problems from the macro-areas of diffusion, propagation and transport, waves and vibrations. In turn the second part, chapters 6 to 11, concentrates on the development of Hilbert spaces methods for the variational formulation and the analysis of (mainly) linear bo...

  3. Partial differential equations in action from modelling to theory

    CERN Document Server

    Salsa, Sandro

    2015-01-01

    The book is intended as an advanced undergraduate or first-year graduate course for students from various disciplines, including applied mathematics, physics and engineering. It has evolved from courses offered on partial differential equations (PDEs) over the last several years at the Politecnico di Milano. These courses had a twofold purpose: on the one hand, to teach students to appreciate the interplay between theory and modeling in problems arising in the applied sciences, and on the other to provide them with a solid theoretical background in numerical methods, such as finite elements. Accordingly, this textbook is divided into two parts. The first part, chapters 2 to 5, is more elementary in nature and focuses on developing and studying basic problems from the macro-areas of diffusion, propagation and transport, waves and vibrations. In turn the second part, chapters 6 to 11, concentrates on the development of Hilbert spaces methods for the variational formulation and the analysis of (mainly) linear bo...

  4. A model for production, perception, and acquisition of actions in face-to-face communication.

    Science.gov (United States)

    Kröger, Bernd J; Kopp, Stefan; Lowit, Anja

    2010-08-01

    The concept of action as basic motor control unit for goal-directed movement behavior has been used primarily for private or non-communicative actions like walking, reaching, or grasping. In this paper, literature is reviewed indicating that this concept can also be used in all domains of face-to-face communication like speech, co-verbal facial expression, and co-verbal gesturing. Three domain-specific types of actions, i.e. speech actions, facial actions, and hand-arm actions, are defined in this paper and a model is proposed that elucidates the underlying biological mechanisms of action production, action perception, and action acquisition in all domains of face-to-face communication. This model can be used as theoretical framework for empirical analysis or simulation with embodied conversational agents, and thus for advanced human-computer interaction technologies.

  5. Mapping from Speech to Images Using Continuous State Space Models

    DEFF Research Database (Denmark)

    Lehn-Schiøler, Tue; Hansen, Lars Kai; Larsen, Jan

    2005-01-01

    In this paper a system that transforms speech waveforms to animated faces are proposed. The system relies on continuous state space models to perform the mapping, this makes it possible to ensure video with no sudden jumps and allows continuous control of the parameters in 'face space'. The perfo......In this paper a system that transforms speech waveforms to animated faces are proposed. The system relies on continuous state space models to perform the mapping, this makes it possible to ensure video with no sudden jumps and allows continuous control of the parameters in 'face space...

  6. Fundamental State Space Time Series Models for JEPX Electricity Prices

    Science.gov (United States)

    Ofuji, Kenta; Kanemoto, Shigeru

    Time series models are popular in attempts to model and forecast price dynamics in various markets. In this paper, we have formulated two state space models and tested them for its applicability to power price modeling and forecasting using JEPX (Japan Electric Power eXchange) data. The state space models generally have a high degree of flexibility with its time-dependent state transition matrix and system equation configurations. Based on empirical data analysis and past literatures, we used calculation assumptions to a) extract stochastic trend component to capture non-stationarity, and b) detect structural changes underlying in the market. The stepwise calculation algorithm followed that of Kalman Filter. We then evaluated the two models' forecasting capabilities, in comparison with ordinary AR (autoregressive) and ARCH (autoregressive conditional heteroskedasticity) models. By choosing proper explanatory variables, the latter state space model yielded as good a forecasting capability as that of the AR and the ARCH models for a short forecasting horizon.

  7. Track structure model of cell damage in space flight

    Science.gov (United States)

    Katz, Robert; Cucinotta, Francis A.; Wilson, John W.; Shinn, Judy L.; Ngo, Duc M.

    1992-01-01

    The phenomenological track-structure model of cell damage is discussed. A description of the application of the track-structure model with the NASA Langley transport code for laboratory and space radiation is given. Comparisons to experimental results for cell survival during exposure to monoenergetic, heavy-ion beams are made. The model is also applied to predict cell damage rates and relative biological effectiveness for deep-space exposures.

  8. Mathematical Model of the Public Understanding of Space Science

    Science.gov (United States)

    Prisniakov, V.; Prisniakova, L.

    The success in deployment of the space programs now in many respects depends on comprehension by the citizens of necessity of programs, from "space" erudition of country. Purposefulness and efficiency of the "space" teaching and educational activity depend on knowledge of relationships between separate variables of such process. The empirical methods of ``space'' well-information of the taxpayers should be supplemented by theoretical models permitting to demonstrate a ways of control by these processes. Authors on the basis of their experience of educational activity during 50- years of among the students of space-rocket profession obtain an equation of ``space" state of the society determining a degree of its knowledge about Space, about achievements in its development, about indispensable lines of investigations, rates of informatization of the population. It is supposed, that the change of the space information consists of two parts: (1) - from going of the information about practical achievements, about development special knowledge requiring of independent financing, and (2) from intensity of dissemination of the ``free" information of a general educational line going to the population through mass-media, book, in family, in educational institutions, as a part of obligatory knowledge of any man, etc. In proposed model the level space well-information of the population depends on intensity of dissemination in the society of the space information, and also from a volume of financing of space-rocket technology, from a part of population of the employment in the space-rocket programs, from a factor of education of the population in adherence to space problems, from welfare and mentality of the people, from a rate of unemployment and material inequality. Obtained in the report on these principles the equation of a space state of the society corresponds to catastrophe such as cusp, the analysis has shown which one ways of control of the public understanding of space

  9. Joint modeling of primary and secondary action in DBM

    NARCIS (Netherlands)

    Koning, Ruud H.; Spring, P.N.; Wansbeek, T.J.

    2002-01-01

    In this paper we discuss the issue of primary and secondary actions to direct mail offers. Primary action refers to the first responses consumers make toward a direct offer or soliciation. It might represent an order for a product, a request for a catalog or credit card, or a pledge to donate to a

  10. Joint modeling of primary and secondary action in database marketing

    NARCIS (Netherlands)

    Koning, Ruud; Spring, Penny; Wansbeek, Tom

    2002-01-01

    In this paper we discuss the issue of primary and secondary actions to direct mail offers. Primary action refers to the first responses consumers make toward a direct offer or solicitation. It might represent an order for a product, a request for a catalog or credit card, or a pledge to donate to a

  11. The Reflective Teacher Leader: An Action Research Model

    Science.gov (United States)

    Furtado, Leena; Anderson, Dawnette

    2012-01-01

    This study presents four teacher reflections from action research projects ranging from kindergarten to adult school improvements. A teacher leadership matrix guided participants to connect teaching and learning theory to best practices by exploring uncharted territory within an iterative cycle of research and action. Teachers developed the…

  12. The Pleurodele, an animal model for space biology studies

    Science.gov (United States)

    Gualandris, L.; Grinfeld, S.; Foulquier, F.; Kan, P.; Duprat, A. M.

    Pleurodeles waltl, an Urodele amphibian is proposed as a model for space biology studies. Our laboratory is developing three types of experiments in space using this animal: 1) in vivo fertilization and development (``FERTILE'' project); 2) influence of microgravity and space radiation on the organization and preservation of spacialized structures in the neurons and muscle cells (in vitro; ``CELIMENE'' PROJECT); 3) influence of microgravity on tissue regeneration (muscle, bone, epidermis and spinal cord).

  13. Modeling the long-term evolution of space debris

    Science.gov (United States)

    Nikolaev, Sergei; De Vries, Willem H.; Henderson, John R.; Horsley, Matthew A.; Jiang, Ming; Levatin, Joanne L.; Olivier, Scot S.; Pertica, Alexander J.; Phillion, Donald W.; Springer, Harry K.

    2017-03-07

    A space object modeling system that models the evolution of space debris is provided. The modeling system simulates interaction of space objects at simulation times throughout a simulation period. The modeling system includes a propagator that calculates the position of each object at each simulation time based on orbital parameters. The modeling system also includes a collision detector that, for each pair of objects at each simulation time, performs a collision analysis. When the distance between objects satisfies a conjunction criterion, the modeling system calculates a local minimum distance between the pair of objects based on a curve fitting to identify a time of closest approach at the simulation times and calculating the position of the objects at the identified time. When the local minimum distance satisfies a collision criterion, the modeling system models the debris created by the collision of the pair of objects.

  14. Payload maintenance cost model for the space telescope

    Science.gov (United States)

    White, W. L.

    1980-01-01

    An optimum maintenance cost model for the space telescope for a fifteen year mission cycle was developed. Various documents and subsequent updates of failure rates and configurations were made. The reliability of the space telescope for one year, two and one half years, and five years were determined using the failure rates and configurations. The failure rates and configurations were also used in the maintenance simulation computer model which simulate the failure patterns for the fifteen year mission life of the space telescope. Cost algorithms associated with the maintenance options as indicated by the failure patterns were developed and integrated into the model.

  15. Bootstrapping Critical Ising Model on Three Dimensional Real Projective Space.

    Science.gov (United States)

    Nakayama, Yu

    2016-04-08

    Given conformal data on a flat Euclidean space, we use crosscap conformal bootstrap equations to numerically solve the Lee-Yang model as well as the critical Ising model on a three dimensional real projective space. We check the rapid convergence of our bootstrap program in two dimensions from the exact solutions available. Based on the comparison, we estimate that our systematic error on the numerically solved one-point functions of the critical Ising model on a three dimensional real projective space is less than 1%. Our method opens up a novel way to solve conformal field theories on nontrivial geometries.

  16. Information metric on instanton moduli spaces in nonlinear sigma models.

    Science.gov (United States)

    Yahikozawa, Shigeaki

    2004-02-01

    We study the information metric on instanton moduli spaces in two-dimensional nonlinear sigma models. In the CP1 model, the information metric on the moduli space of one instanton with the topological charge Q=k(k > or =1) is a three-dimensional hyperbolic metric, which corresponds to Euclidean anti-de Sitter space-time metric in three dimensions, and the overall scale factor of the information metric is 4k(2)/3; this means that the sectional curvature is -3/4k(2). We also calculate the information metric in the CP2 model.

  17. Simulation Modeling of Space Missions Using the High Level Architecture

    Directory of Open Access Journals (Sweden)

    Luis Rabelo

    2013-01-01

    Full Text Available This paper discusses an environment being developed to model a mission of the Space Launch System (SLS and the Multipurpose Crew Vehicle (MPCV being launched from Kennedy Space Center (KSC to the International Space Station (ISS. Several models representing different phases of the mission such as the ground operations processes, engineered systems, and range components such as failure tree, blast, gas dispersion, and debris modeling are explained. These models are built using different simulation paradigms such as continuous, system dynamics, discrete-event, and agent-based simulation modeling. The High Level Architecture (HLA is the backbone of this distributed simulation. The different design decisions and the information fusion scheme of this unique environment are explained in detail for decision-making. This can also help in the development of exploration missions beyond the International Space Station.

  18. A Learning State-Space Model for Image Retrieval

    Directory of Open Access Journals (Sweden)

    Lee Greg C

    2007-01-01

    Full Text Available This paper proposes an approach based on a state-space model for learning the user concepts in image retrieval. We first design a scheme of region-based image representation based on concept units, which are integrated with different types of feature spaces and with different region scales of image segmentation. The design of the concept units aims at describing similar characteristics at a certain perspective among relevant images. We present the details of our proposed approach based on a state-space model for interactive image retrieval, including likelihood and transition models, and we also describe some experiments that show the efficacy of our proposed model. This work demonstrates the feasibility of using a state-space model to estimate the user intuition in image retrieval.

  19. Quantum-Dot Semiconductor Optical Amplifiers: State Space Model versus Rate Equation Model

    Directory of Open Access Journals (Sweden)

    Hussein Taleb

    2013-01-01

    Full Text Available A simple and accurate dynamic model for QD-SOAs is proposed. The proposed model is based on the state space theory, where by eliminating the distance dependence of the rate equation model of the QD-SOA; we derive a state space model for the device. A comparison is made between the rate equation model and the state space model under both steady state and transient regimes. Simulation results demonstrate that the derived state space model not only is much simpler and faster than the rate equation model, but also it is as accurate as the rate equation model.

  20. Uncertainty Driven Action (UDA) model: A foundation for unifying perspectives on design activity

    DEFF Research Database (Denmark)

    Cash, Philip; Kreye, Melanie

    2017-01-01

    This paper proposes the Uncertainty Driven Action (UDA) model, which unifies the fragmented literature on design activity. The UDA model conceptualises design activity as a process consisting of three core actions: information action, knowledge-sharing action, and representation action, which...... are linked via uncertainty perception. The foundations of the UDA model in the design literature are elaborated in terms of the three core actions and their links to designer cognition and behaviour, utilising definitions and concepts from Activity Theory. The practical relevance and theoretical...... contributions of the UDA model are discussed. This paper contributes to the design literature by offering a comprehensive formalisation of design activity of individual designers, which connects cognition and action, to provide a foundation for understanding previously disparate descriptions of design activity....

  1. Model of the physical space from quantum mechanics

    Science.gov (United States)

    Kong, Otto C. W.

    2017-08-01

    The physical world is quantum. However, our description of the quantum physics still relies much on concepts in classical physics and in some cases with ‘quantized’ interpretations. The most important case example is that of spacetime. We examine the picture of the physical space as described by simple, so-called non-relativisitic, quantum mechanics instead of assuming the Newtonian model. The key perspective is that of (relativity) symmetry representation, and the idea that the physical space is to be identified as the configuration space for a free particle. Parallel to the case of the phase space, we have a model of the quantum physical space which reduces to the Newtonian classical model under the classical limit. The latter is to be obtained as a contraction limit of the relativity symmetry.

  2. Paraboloidal Space-Times and Relativistic Models of Strange Stars

    Science.gov (United States)

    Jotania, Kanti; Tikekar, Ramesh

    The objective of this paper is to find out the suitability of an ansatz similar to that suggested by Vaidya-Tikekar, but prescribing paraboloidal geometry for the 3-space of the interior space-time of a relativistic spherical star in describing a family of physically viable models of superdense stars like Her X-1, SAX, and X-ray brust.

  3. The Use of Models in Urban Space Pattern Analysis | Berhanu ...

    African Journals Online (AJOL)

    This paper focuses on the use of urban space pattern analysis methods. Physical developments once located in space influence a set of social and economic activities. These days urban developments are of large scale and very fast, often involving complex issues. Models are usually used to reduce complexities in ...

  4. Acting in solidarity : Testing an extended dual pathway model of collective action by bystander group members

    NARCIS (Netherlands)

    Saab, Rim; Tausch, Nicole; Spears, Russell; Cheung, Wing-Yee

    We examined predictors of collective action among bystander group members in solidarity with a disadvantaged group by extending the dual pathway model of collective action, which proposes one efficacy-based and one emotion-based path to collective action (Van Zomeren, Spears, Fischer, & Leach,

  5. A Novel Reinforcement Learning Architecture for Continuous State and Action Spaces

    Directory of Open Access Journals (Sweden)

    Víctor Uc-Cetina

    2013-01-01

    in two actors the work required to learn the final policy. One actor decides what action must be performed; meanwhile, a second actor determines the right parameters for the selected action. We tested our architecture and one algorithm based on it solving the robot dribbling problem, a challenging robot control problem taken from the RoboCup competitions. Our experimental work with three different function approximators provides enough evidence to prove that the proposed architecture can be used to implement fast, robust, and reliable reinforcement learning algorithms.

  6. Space-propagation model of Tm-doped fiber laser.

    Science.gov (United States)

    Lü, Haibin; Zhou, Pu; Wang, Xiaolin; Jiang, Zongfu

    2012-11-01

    In this paper, we propose the space-propagation model for the Tm-doped fiber laser. This model builds the space-propagation equations for the population densities at different energy levels as well as the pump and laser powers. Compared to the conventional models, this model has significant advantage in reducing the computing time significantly when the steady-state population density rate equations cannot be solved analytically. On the basis of the model, the power characteristic and optimization for the Tm-doped fiber laser are investigated. Excellent agreements are achieved between the numerical simulation and experimental results.

  7. Adaptive coding of orofacial and speech actions in motor and somatosensory spaces with and without overt motor behavior.

    Science.gov (United States)

    Sato, Marc; Vilain, Coriandre; Lamalle, Laurent; Grabski, Krystyna

    2015-02-01

    Studies of speech motor control suggest that articulatory and phonemic goals are defined in multidimensional motor, somatosensory, and auditory spaces. To test whether motor simulation might rely on sensory-motor coding common with those for motor execution, we used a repetition suppression (RS) paradigm while measuring neural activity with sparse sampling fMRI during repeated overt and covert orofacial and speech actions. RS refers to the phenomenon that repeated stimuli or motor acts lead to decreased activity in specific neural populations and are associated with enhanced adaptive learning related to the repeated stimulus attributes. Common suppressed neural responses were observed in motor and posterior parietal regions in the achievement of both repeated overt and covert orofacial and speech actions, including the left premotor cortex and inferior frontal gyrus, the superior parietal cortex and adjacent intraprietal sulcus, and the left IC and the SMA. Interestingly, reduced activity of the auditory cortex was observed during overt but not covert speech production, a finding likely reflecting a motor rather an auditory imagery strategy by the participants. By providing evidence for adaptive changes in premotor and associative somatosensory brain areas, the observed RS suggests online state coding of both orofacial and speech actions in somatosensory and motor spaces with and without motor behavior and sensory feedback.

  8. Space ecoliteracy- five informal education models for community empowerment

    Science.gov (United States)

    Venkataramaiah, Jagannatha; Jagannath, Sahana; J, Spandana; J, Sadhana; Jagannath, Shobha

    Space ecoliteracy is a historical necessity and vital aspect of space age.Space Situational Awareness has taught lessons for mankind to look inward while stretching beyond cradle in human endeavours. Quality of life for every one on the only home of mankind-TERRA shall be a feasibility only after realizing Space ecoliteracy amongst all stakeholders in space quest. Objectives of Informal Environmental Education(UNESCO/UNEP/IEEP,1977) mandates awareness, attitude, knowledge, skill and participation at Individual and Community domains. Application of Space Technology at both Telecommunications and Remote Sensing domain have started making the fact that mankind has a challenge to learn and affirm earthmanship. Community empowerment focus after Earth Summit 1992 mandate of Sustainable Development has demonstrated a deluge of best practices in Agriculture,Urban, Industries and service sectors all over the globe. Further, deployment of Space technologies have proved the immense potential only after pre-empting the participatory approach at individual and community levels.Indian Space Programme with its 44th year of space service to national development has demonstrated self reliance in space technology for human development. Space technology for the most underdeveloped is a success story both in communication and information tools for quality of life. In this presentation Five Space Ecoliteracy models designed and validated since 1985 till date on informal environmental education namely 1) Ecological Environmental Studies by Students-EESS (1988): cited as one of the 20 best eco -education models by Earth Day Network,2)Community Eco Literacy Campaign-CEL,(2000): cited as a partner under Clean Up the World Campaign,UN, 3) Space Eco Literacy(2011)-an informa 8 week space eco literacy training reported at 39th COSPAR 12 assembly and 4) Space Eco Literacy by Practice(2014)- interface with formal education at institutions and 5) Space Ecoliteracy Mission as a space out reach in

  9. Standard State Space Models of Unawareness (Extended Abstract

    Directory of Open Access Journals (Sweden)

    Peter Fritz

    2016-06-01

    Full Text Available The impossibility theorem of Dekel, Lipman and Rustichini has been thought to demonstrate that standard state-space models cannot be used to represent unawareness. We first show that Dekel, Lipman and Rustichini do not establish this claim. We then distinguish three notions of awareness, and argue that although one of them may not be adequately modeled using standard state spaces, there is no reason to think that standard state spaces cannot provide models of the other two notions. In fact, standard space models of these forms of awareness are attractively simple. They allow us to prove completeness and decidability results with ease, to carry over standard techniques from decision theory, and to add propositional quantifiers straightforwardly.

  10. Modeling and Observations of Optical Space Weathering on Vesta

    Science.gov (United States)

    Blewett, D. T.; Denevi, B. W.; Le Corre, L.; Reddy, V.; Schroder, S. E.; Pieters, C. M.; Tosi, F.; Zambon, F.; De Sanctis, M. C.; Ammannito, E.; Roatsch, T.; Raymond, C. A.; Russell, C. T.

    2015-11-01

    We use Hapke model spectra to predict the effects of lunar-style space weathering on Vesta, contrast with the effects of mixing with carbonaceous-chondrite material, and to guide interpretation of Dawn multispectral observations of Vesta.

  11. Action Algebras and Model Algebras in Denotational Semantics

    Science.gov (United States)

    Guedes, Luiz Carlos Castro; Haeusler, Edward Hermann

    the same way as that for functional denotational types. For example, PASCAL arrays belong to the “language inherent” aspect, while the Store domain seems to belong to the “model dependent” aspect. This distinction was important because it focussed attention on optimizing the model dependent semantic domains to obtain a more efficient implementation.) The research led to a nice conclusion: The guidelines of Action Semantics induce a clear separation of the model and language inherent aspects of a language’s semantics. A good implementation of facets, particularly the model dependent ones, leads to generation of an efficient compiler. In this article we discuss the separation of the language inherent and model-inherent domains at the theoretical and conceptual level. In doing so, the authors hope to show how Professor Mosses’s influence extended beyond his technical advice to his professional and personal examples on the supervision of PhD research.

  12. A Situative Space Model for Mobile Mixed-Reality Computing

    DEFF Research Database (Denmark)

    Pederson, Thomas; Janlert, Lars-Erik; Surie, Dipak

    2011-01-01

    This article proposes a situative space model that links the physical and virtual realms and sets the stage for complex human-computer interaction defined by what a human agent can see, hear, and touch, at any given point in time.......This article proposes a situative space model that links the physical and virtual realms and sets the stage for complex human-computer interaction defined by what a human agent can see, hear, and touch, at any given point in time....

  13. Space engineering modeling and optimization with case studies

    CERN Document Server

    Pintér, János

    2016-01-01

    This book presents a selection of advanced case studies that cover a substantial range of issues and real-world challenges and applications in space engineering. Vital mathematical modeling, optimization methodologies and numerical solution aspects of each application case study are presented in detail, with discussions of a range of advanced model development and solution techniques and tools. Space engineering challenges are discussed in the following contexts: •Advanced Space Vehicle Design •Computation of Optimal Low Thrust Transfers •Indirect Optimization of Spacecraft Trajectories •Resource-Constrained Scheduling, •Packing Problems in Space •Design of Complex Interplanetary Trajectories •Satellite Constellation Image Acquisition •Re-entry Test Vehicle Configuration Selection •Collision Risk Assessment on Perturbed Orbits •Optimal Robust Design of Hybrid Rocket Engines •Nonlinear Regression Analysis in Space Engineering< •Regression-Based Sensitivity Analysis and Robust Design ...

  14. A reference model for space data system interconnection services

    Science.gov (United States)

    Pietras, John; Theis, Gerhard

    1993-01-01

    The widespread adoption of standard packet-based data communication protocols and services for spaceflight missions provides the foundation for other standard space data handling services. These space data handling services can be defined as increasingly sophisticated processing of data or information received from lower-level services, using a layering approach made famous in the International Organization for Standardization (ISO) Open System Interconnection Reference Model (OSI-RM). The Space Data System Interconnection Reference Model (SDSI-RM) incorporates the conventions of the OSIRM to provide a framework within which a complete set of space data handling services can be defined. The use of the SDSI-RM is illustrated through its application to data handling services and protocols that have been defined by, or are under consideration by, the Consultative Committee for Space Data Systems (CCSDS).

  15. Indoor Space Location Model Based on Location Service

    Science.gov (United States)

    Zhou, Y.; Zeng, G.; Huang, Y.; Yang, X.

    2017-10-01

    Location is the basis for the realization of location services, the integrity of the location information and its way of representation in indoor space model directly restricts the quality of location services. The construction of the existing indoor space model is mostly for specific applications and lack of uniform representation of location information. Several geospatial standards have been developed to meet the requirement of the indoor spatial information system, among which CityGML LOD4 and IndoorGML are the most relevant ones for indoor spatial information. However, from the perspective of Location Based Service (LBS), the CityGML LOD4 is more inclined to visualize the indoor space. Although IndoorGML is mainly used for indoor space navigation and has description (such as geometry, topology, and semantics) benefiting for indoor LBS, this standard model lack explicit representation of indoor location information. In this paper, from the perspective of Location Based Service (LBS), based on the IndoorGML standard, an indoor space location model (ISLM) conforming to human cognition is proposed through integration of the geometric and topological and semantic features of the indoor spatial entity. This model has the explicit description of location information which the standard indoor space model of IndoorGML and CityGML LOD4 does not have, which can lay the theoretical foundation for indoor location service such as indoor navigation, indoor routing and location query.

  16. Emergent gravity on covariant quantum spaces in the IKKT model

    Energy Technology Data Exchange (ETDEWEB)

    Steinacker, Harold C. [Faculty of Physics, University of Vienna,Boltzmanngasse 5, A-1090 Vienna (Austria)

    2016-12-30

    We study perturbations of 4-dimensional fuzzy spheres as backgrounds in the IKKT or IIB matrix model. Gauge fields and metric fluctuations are identified among the excitation modes with lowest spin, supplemented by a tower of higher-spin fields. They arise from an internal structure which can be viewed as a twisted bundle over S{sup 4}, leading to a covariant noncommutative geometry. The linearized 4-dimensional Einstein equations are obtained from the classical matrix model action under certain conditions, modified by an IR cutoff. Some one-loop contributions to the effective action are computed using the formalism of string states.

  17. Quillen equivalences between the model categories of smooth spaces, simplicial sets, and arc-gengerated spaces

    OpenAIRE

    Kihara, Hiroshi

    2017-01-01

    In the preceding paper, we have constructed a compactly generated model structure on the category $\\dcal$ of diffeological spaces together with the adjoint pairs $|\\ |_\\dcal : \\scal \\rightleftarrows \\dcal : S^\\dcal$ and $\\tilde{\\cdot} : \\dcal \\rightleftarrows \\ccal^0 : R$, where $\\scal$ and $\\ccal^0$ denote the category of simplicial sets and that of arc-generated spaces, respectively. In this paper, we show that $(|\\ |_\\dcal, S^\\dcal)$ and $(\\tilde{\\cdot}, R)$ are pairs of Quillen equivalenc...

  18. Parametric study of the Noble's action potential model for cardiac Purkinje fibers

    Energy Technology Data Exchange (ETDEWEB)

    Wang, P.K.C. [Department of Electrical Engineering, University of California, Los Angeles, CA 90095-1594 (United States); Kogan, B.Y. [Department of Computer Science, University of California, Los Angeles, CA 90095-1594 (United States)]. E-mail: kogan@cs.ucla.edu

    2007-08-15

    The effect of parameter variation on repolarization processes in the Noble model (Hodjkin-Huxley type) for action potential (AP) generation in Purkinje cells is studied using a combination of computer simulation and nonlinear dynamic system theory including Hopf bifurcation analysis. Both the original Noble model and a simplified Noble model are used in this study. It is shown that these models have similar qualitative dynamic behavior in the presence of parameter variations. In particular, it is demonstrated that both normal and abnormal modes of cell performance can be obtained by varying the potassium and anion conductances. The abnormal mode (cardiac arrest) may play a significant role in disorganizing the electrical activities in the heart muscles. The existence of Hopf bifurcation with respect to variations in the anion conductance and fixed values of potassium conductances is studied in detail. The regions corresponding to spontaneous AP excitation, and various types of cardiac arrest in the ion-conductance parameter space of both full and simplified Noble models with and without external stimuli are mapped out using computer simulation.

  19. Validation of ecological state space models using the Laplace approximation

    DEFF Research Database (Denmark)

    Thygesen, Uffe Høgsbro; Albertsen, Christoffer Moesgaard; Berg, Casper Willestofte

    2017-01-01

    Many statistical models in ecology follow the state space paradigm. For such models, the important step of model validation rarely receives as much attention as estimation or hypothesis testing, perhaps due to lack of available algorithms and software. Model validation is often based on a naive...... for estimation in general mixed effects models. Implementing one-step predictions in the R package Template Model Builder, we demonstrate that it is possible to perform model validation with little effort, even if the ecological model is multivariate, has non-linear dynamics, and whether observations...

  20. Pilot-Wave Quantum Theory in Discrete Space and Time and the Principle of Least Action

    Science.gov (United States)

    Gluza, Janusz; Kosek, Jerzy

    2016-11-01

    The idea of obtaining a pilot-wave quantum theory on a lattice with discrete time is presented. The motion of quantum particles is described by a |Ψ |^2-distributed Markov chain. Stochastic matrices of the process are found by the discrete version of the least-action principle. Probability currents are the consequence of Hamilton's principle and the stochasticity of the Markov process is minimized. As an example, stochastic motion of single particles in a double-slit experiment is examined.

  1. Actions Needed to Ensure Scientific and Technical Information is Adequately Reviewed at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center

    Science.gov (United States)

    2008-01-01

    This audit was initiated in response to a hotline complaint regarding the review, approval, and release of scientific and technical information (STI) at Johnson Space Center. The complainant alleged that Johnson personnel conducting export control reviews of STI were not fully qualified to conduct those reviews and that the reviews often did not occur until after the STI had been publicly released. NASA guidance requires that STI, defined as the results of basic and applied scientific, technical, and related engineering research and development, undergo certain reviews prior to being released outside of NASA or to audiences that include foreign nationals. The process includes technical, national security, export control, copyright, and trade secret (e.g., proprietary data) reviews. The review process was designed to preclude the inappropriate dissemination of sensitive information while ensuring that NASA complies with a requirement of the National Aeronautics and Space Act of 1958 (the Space Act)1 to provide for the widest practicable and appropriate dissemination of information resulting from NASA research activities. We focused our audit on evaluating the STI review process: specifically, determining whether the roles and responsibilities for the review, approval, and release of STI were adequately defined and documented in NASA and Center-level guidance and whether that guidance was effectively implemented at Goddard Space Flight Center, Johnson Space Center, Langley Research Center, and Marshall Space Flight Center. Johnson was included in the review because it was the source of the initial complaint, and Goddard, Langley, and Marshall were included because those Centers consistently produce significant amounts of STI.

  2. Einstein's ``Spooky Action at a Distance'' in the Light of Kant's Transcendental Doctrine of Space and Time

    Science.gov (United States)

    Hacyan, Shahen

    2006-11-01

    Since the famous Einstein-Podolsky-Rosen (EPR) paper, it is clear that there is a serious incompatibility between local realism and quantum mechanics. Einstein believed that a complete quantum theory should be free of what he once called "spooky actions at distance". However, all experiments in quantum optics and atomic physics performed in the last two decades confirm the existence of quantum correlations that seem to contradict local realism. According to Bohr, the apparent contradictions disclose only the inadequacy of our customary concepts for the description of the quantum world. Are space and time such customary concepts? In this presentation, I argue that the Copenhagen interpretation is compatible with Kant's transcendental idealism and that, in particular, EPR type paradoxes are consistent with Kant's transcendental aesthetics, according to which space and time have no objective reality but are pure forms of sensible intuition.

  3. Royal London space analysis: plaster versus digital model assessment.

    Science.gov (United States)

    Grewal, Balpreet; Lee, Robert T; Zou, Lifong; Johal, Ama

    2017-06-01

    With the advent of digital study models, the importance of being able to evaluate space requirements becomes valuable to treatment planning and the justification for any required extraction pattern. This study was undertaken to compare the validity and reliability of the Royal London space analysis (RLSA) undertaken on plaster as compared with digital models. A pilot study (n = 5) was undertaken on plaster and digital models to evaluate the feasibility of digital space planning. This also helped to determine the sample size calculation and as a result, 30 sets of study models with specified inclusion criteria were selected. All five components of the RLSA, namely: crowding; depth of occlusal curve; arch expansion/contraction; incisor antero-posterior advancement and inclination (assessed from the pre-treatment lateral cephalogram) were accounted for in relation to both model types. The plaster models served as the gold standard. Intra-operator measurement error (reliability) was evaluated along with a direct comparison of the measured digital values (validity) with the plaster models. The measurement error or coefficient of repeatability was comparable for plaster and digital space analyses and ranged from 0.66 to 0.95mm. No difference was found between the space analysis performed in either the upper or lower dental arch. Hence, the null hypothesis was accepted. The digital model measurements were consistently larger, albeit by a relatively small amount, than the plaster models (0.35mm upper arch and 0.32mm lower arch). No difference was detected in the RLSA when performed using either plaster or digital models. Thus, digital space analysis provides a valid and reproducible alternative method in the new era of digital records.

  4. Space Weather Models, Tools and Services at the Community Coordinated Modeling Center

    Science.gov (United States)

    Kuznetsova, M. M.; Hesse, M.; Maddox, M.; Rastaetter, L.; Berrios, D.; Pulkkinen, A.; Zheng, Y.; MacNeice, P. J.; Shim, J.; Takakishvili, A.; hide

    2010-01-01

    The Community Coordinated Modeling center (CCMC) is a multi-agency partnership to support the research and developmental work necessary to substantially increase space weather modeling capabilities and to facilitate advanced models deployment in forecasting operations. The CCMC conducts unbiased model testing and validation and evaluates model readiness for operational environment. Space weather models and coupled model chains hosted at the CCMC range from the solar corona to the Earth's upper atmosphere. CCMC has developed a number of real-time modeling systems, as well as a large number of modeling and data products tailored to address the space weather needs of NASA's robotic missions. The presentation will demonstrate the rapid progress towards development the system allowing using products derived from space weather models in applications associated with National Space Weather needs. The adaptable Integrated Space Weather Analysis (ISWA) System developed at CCMC for NASA-relevant space weather information combines forecasts based on advanced space weather models hosted at CCMC with concurrent space environment information. The system is also enabling post-impact analysis and flexible dissemination of space weather information.

  5. Modelling the differential effects of prisms on perception and action in neglect.

    Science.gov (United States)

    Leigh, Steven; Danckert, James; Eliasmith, Chris

    2015-03-01

    Damage to the right parietal cortex often leads to a syndrome known as unilateral neglect in which the patient fails to attend or respond to stimuli in left space. Recent work attempting to rehabilitate the disorder has made use of rightward-shifting prisms that displace visual input further rightward. After a brief period of adaptation to prisms, many of the symptoms of neglect show improvements that can last for hours or longer, depending on the adaptation procedure. Recent work has shown, however, that differential effects of prisms can be observed on actions (which are typically improved) and perceptual biases (which often remain unchanged). Here, we present a computational model capable of explaining some basic symptoms of neglect (line bisection behaviour), the effects of prism adaptation in both healthy controls and neglect patients and the observed dissociation between action and perception following prisms. The results of our simulations support recent contentions that prisms primarily influence behaviours normally thought to be controlled by the dorsal stream.

  6. Space Mapping Optimization of Microwave Circuits Exploiting Surrogate Models

    DEFF Research Database (Denmark)

    Bakr, M. H.; Bandler, J. W.; Madsen, Kaj

    2000-01-01

    is a convex combination of a mapped coarse model and a linearized fine model. It exploits, in a novel way, a linear frequency-sensitive mapping. During the optimization iterates, the coarse and fine models are simulated at different sets of frequencies. This approach is shown to be especially powerful......A powerful new space-mapping (SM) optimization algorithm is presented in this paper. It draws upon recent developments in both surrogate model-based optimization and modeling of microwave devices, SM optimization is formulated as a general optimization problem of a surrogate model. This model...

  7. Space-time modeling of electricity spot prices

    DEFF Research Database (Denmark)

    Abate, Girum Dagnachew; Haldrup, Niels

    In this paper we derive a space-time model for electricity spot prices. A general spatial Durbin model that incorporates the temporal as well as spatial lags of spot prices is presented. Joint modeling of space-time effects is necessarily important when prices and loads are determined in a network...... of power exchange areas. We use data from the Nord Pool electricity power exchange area bidding markets. Different spatial weight matrices are considered to capture the structure of the spatial dependence process across different bidding markets and statistical tests show significant spatial dependence...

  8. Estimation methods for nonlinear state-space models in ecology

    DEFF Research Database (Denmark)

    Pedersen, Martin Wæver; Berg, Casper Willestofte; Thygesen, Uffe Høgsbro

    2011-01-01

    The use of nonlinear state-space models for analyzing ecological systems is increasing. A wide range of estimation methods for such models are available to ecologists, however it is not always clear, which is the appropriate method to choose. To this end, three approaches to estimation in the theta...... logistic model for population dynamics were benchmarked by Wang (2007). Similarly, we examine and compare the estimation performance of three alternative methods using simulated data. The first approach is to partition the state-space into a finite number of states and formulate the problem as a hidden...

  9. Applying reliability models to the maintenance of Space Shuttle software

    Science.gov (United States)

    Schneidewind, Norman F.

    1992-01-01

    Software reliability models provide the software manager with a powerful tool for predicting, controlling, and assessing the reliability of software during maintenance. We show how a reliability model can be effectively employed for reliability prediction and the development of maintenance strategies using the Space Shuttle Primary Avionics Software Subsystem as an example.

  10. Critical examination of knowledge to action models and implications for promoting health equity.

    Science.gov (United States)

    Davison, Colleen M; Ndumbe-Eyoh, Sume; Clement, Connie

    2015-05-29

    Knowledge and effective interventions exist to address many current global health inequities. However, there is limited awareness, uptake, and use of knowledge to inform action to improve the health of disadvantaged populations. The gap between knowledge and action to improve health equity is of concern to health researchers and practitioners. This study identifies and critically examines the usefulness of existing knowledge to action models or frameworks for promoting health equity. We conducted a scoping review of existing literature to identify knowledge to action (KTA) models or frameworks and critiqued the models using a health equity support rubric. We identified forty-eight knowledge to action models or frameworks. Six models scored between eight and ten of a maximum 12 points on the health equity support rubric. These high scoring models or frameworks all mentioned equity-related concepts. Attention to multisectoral approaches was the factor most often lacking in the low scoring models. The concepts of knowledge brokering, integrative processes, such as those in some indigenous health research, and Ecohealth applied to KTA all emerged as promising areas. Existing knowledge to action models or frameworks can help guide knowledge translation to support action on the social determinants of health and health equity. There is a need to further test existing models or frameworks. This process should be informed by participatory and integrative research. There is room to develop more robust equity supporting models.

  11. Integral group actions on symmetric spaces and discrete duality symmetries of supergravity theories

    Energy Technology Data Exchange (ETDEWEB)

    Carbone, Lisa [Mathematics Rutgers University, Hill Center-Busch Campus, 110 Frelinghuysen Rd., Piscataway, New Jersey 08854 (United States); Murray, Scott H. [Mathematics & Statistics, University of Canberra, ACT 2601 (Australia); Sati, Hisham [Department of Mathematics, University of Pittsburgh, 301 Thackeray Hall, Pittsburgh, Pennsylvania 15260 (United States)

    2015-10-15

    For G = G(ℝ), a split, simply connected, semisimple Lie group of rank n and K the maximal compact subgroup of G, we give a method for computing Iwasawa coordinates of K∖G using the Chevalley generators and the Steinberg presentation. When K∖G is a scalar coset for a supergravity theory in dimensions ≥3, we determine the action of the integral form G(ℤ) on K∖G. We give explicit results for the action of the discrete U-duality groups SL{sub 2}(ℤ) and E{sub 7}(ℤ) on the scalar cosets SO(2)∖SL{sub 2}(ℝ) and [SU(8)/( ± Id)]∖E{sub 7(+7)}(ℝ) for type IIB supergravity in ten dimensions and 11-dimensional supergravity reduced to D = 4 dimensions, respectively. For the former, we use this to determine the discrete U-duality transformations on the scalar sector in the Borel gauge and we describe the discrete symmetries of the dyonic charge lattice. We determine the spectrum-generating symmetry group for fundamental BPS solitons of type IIB supergravity in D = 10 dimensions at the classical level and we propose an analog of this symmetry at the quantum level. We indicate how our methods can be used to study the orbits of discrete U-duality groups in general.

  12. Modeling Coastal Vulnerability through Space and Time.

    Science.gov (United States)

    Hopper, Thomas; Meixler, Marcia S

    2016-01-01

    Coastal ecosystems experience a wide range of stressors including wave forces, storm surge, sea-level rise, and anthropogenic modification and are thus vulnerable to erosion. Urban coastal ecosystems are especially important due to the large populations these limited ecosystems serve. However, few studies have addressed the issue of urban coastal vulnerability at the landscape scale with spatial data that are finely resolved. The purpose of this study was to model and map coastal vulnerability and the role of natural habitats in reducing vulnerability in Jamaica Bay, New York, in terms of nine coastal vulnerability metrics (relief, wave exposure, geomorphology, natural habitats, exposure, exposure with no habitat, habitat role, erodible shoreline, and surge) under past (1609), current (2015), and future (2080) scenarios using InVEST 3.2.0. We analyzed vulnerability results both spatially and across all time periods, by stakeholder (ownership) and by distance to damage from Hurricane Sandy. We found significant differences in vulnerability metrics between past, current and future scenarios for all nine metrics except relief and wave exposure. The marsh islands in the center of the bay are currently vulnerable. In the future, these islands will likely be inundated, placing additional areas of the shoreline increasingly at risk. Significant differences in vulnerability exist between stakeholders; the Breezy Point Cooperative and Gateway National Recreation Area had the largest erodible shoreline segments. Significant correlations exist for all vulnerability (exposure/surge) and storm damage combinations except for exposure and distance to artificial debris. Coastal protective features, ranging from storm surge barriers and levees to natural features (e.g. wetlands), have been promoted to decrease future flood risk to communities in coastal areas around the world. Our methods of combining coastal vulnerability results with additional data and across multiple time

  13. A stochastic space-time model for intermittent precipitation occurrences

    KAUST Repository

    Sun, Ying

    2016-01-28

    Modeling a precipitation field is challenging due to its intermittent and highly scale-dependent nature. Motivated by the features of high-frequency precipitation data from a network of rain gauges, we propose a threshold space-time t random field (tRF) model for 15-minute precipitation occurrences. This model is constructed through a space-time Gaussian random field (GRF) with random scaling varying along time or space and time. It can be viewed as a generalization of the purely spatial tRF, and has a hierarchical representation that allows for Bayesian interpretation. Developing appropriate tools for evaluating precipitation models is a crucial part of the model-building process, and we focus on evaluating whether models can produce the observed conditional dry and rain probabilities given that some set of neighboring sites all have rain or all have no rain. These conditional probabilities show that the proposed space-time model has noticeable improvements in some characteristics of joint rainfall occurrences for the data we have considered.

  14. Coupled Learning of Action Parameters and Forward Models for Manipulation

    Science.gov (United States)

    2016-10-09

    rules, predicting high-level, abstract Both authors are with the Robotics and Biology Laboratory , Technische Universität Berlin, Germany. We gratefully...collection: In each scenario, the robot interacts with cabinets in different states (open, locked, closed, un- locked) by randomly selecting the handle , box...mechanisms.) Third, in some training samples an action evokes undesired side effects; e.g., in the box-and- handle scenario the robot simultaneously

  15. Tianeptine in an experimental medicine model of antidepressant action.

    Science.gov (United States)

    Cooper, Charlotte M; Whiting, Daniel A; Cowen, Philip J; Harmer, Catherine J

    2015-05-01

    Changes in emotional processing have been shown following acute administration of a range of monoaminergic antidepressants, and may represent an important common neuropsychological mechanism underpinning their therapeutic effects. Tianeptine is an agent that challenges the traditional monoaminergic hypothesis of antidepressant action, though its exact mode of action remains controversial. Healthy volunteers were randomised to receive a single dose of tianeptine (12.5 mg) or placebo, and subsequently completed a battery of tasks measuring emotional processing, including facial expression recognition, emotional memory and attentional vigilance, as well as working and verbal memory. Tianeptine-treated subjects were less accurate at identifying facial expressions, though this was not valence specific. The tianeptine group also showed reduced positive affective memory and reduced attentional vigilance to positive stimuli. There were no effects on emotional categorization or non-emotional cognition. The negative biases in aspects of emotional processing observed following acute tianeptine administration are at variance with the positive biases generally seen after acute administration of conventional antidepressant drugs, despite tianeptine's putative antidepressant efficacy. This is an intriguing finding in the context of the lack of consensus regarding tianeptine's mechanism of action; however, it may be consistent with the reported ability of acute tianeptine to increase the re-uptake of serotonin. © The Author(s) 2015.

  16. Nongenomic actions of cortisol in the teleost lactotroph model

    DEFF Research Database (Denmark)

    Borski, Russell J; Tipsmark, Christian Kølbæk; Mita, M

    2006-01-01

    The mechanisms underlying rapid nongenomic effects of glucocorticoids is poorly understood. We have previously established that cortisol rapidly suppresses tilapia prolactin (PRL) release through a nongenomic, membrane action that involves rapid reductions in intracellular Ca2+. The aim of the pr......The mechanisms underlying rapid nongenomic effects of glucocorticoids is poorly understood. We have previously established that cortisol rapidly suppresses tilapia prolactin (PRL) release through a nongenomic, membrane action that involves rapid reductions in intracellular Ca2+. The aim...... of the present study was to investigate the role of phospholipase C (PLC)-IP3 in mediating cortisol's actions. During 30 min and 4-hour incubation, chicken GnRH-II induces a 2-4 fold increase in PRL release from the tilapia pituitary. The stimulatory effect of cGnRH-II was reduced by cortisol, cortisol-21......-hemisuccinate (HEF) and its membrane impermeant analog, HEF-BSA. Since GnRH induces PRL release, in part, via activation of PLC this suggests that cortisol may rapidly inhibit GnRH-induced PRL release by suppressing PLC activity. We also found that cortisol rapidly inhibits IP3 accumulation in tilapia RPD under...

  17. Geodetic Space Weather Monitoring by means of Ionosphere Modelling

    Science.gov (United States)

    Schmidt, Michael

    2017-04-01

    The term space weather indicates physical processes and phenomena in space caused by radiation of energy mainly from the Sun. Manifestations of space weather are (1) variations of the Earth's magnetic field, (2) the polar lights in the northern and southern hemisphere, (3) variations within the ionosphere as part of the upper atmosphere characterized by the existence of free electrons and ions, (4) the solar wind, i.e. the permanent emission of electrons and photons, (5) the interplanetary magnetic field, and (6) electric currents, e.g. the van Allen radiation belt. It can be stated that ionosphere disturbances are often caused by so-called solar storms. A solar storm comprises solar events such as solar flares and coronal mass ejections (CMEs) which have different effects on the Earth. Solar flares may cause disturbances in positioning, navigation and communication. CMEs can effect severe disturbances and in extreme cases damages or even destructions of modern infrastructure. Examples are interruptions to satellite services including the global navigation satellite systems (GNSS), communication systems, Earth observation and imaging systems or a potential failure of power networks. Currently the measurements of solar satellite missions such as STEREO and SOHO are used to forecast solar events. Besides these measurements the Earth's ionosphere plays another key role in monitoring the space weather, because it responses to solar storms with an increase of the electron density. Space-geodetic observation techniques, such as terrestrial GNSS, satellite altimetry, space-borne GPS (radio occultation), DORIS and VLBI provide valuable global information about the state of the ionosphere. Additionally geodesy has a long history and large experience in developing and using sophisticated analysis and combination techniques as well as empirical and physical modelling approaches. Consequently, geodesy is predestinated for strongly supporting space weather monitoring via

  18. Enhanced surrogate models for statistical design exploiting space mapping technology

    DEFF Research Database (Denmark)

    Koziel, Slawek; Bandler, John W.; Mohamed, Achmed S.

    2005-01-01

    We present advances in microwave and RF device modeling exploiting Space Mapping (SM) technology. We propose new SM modeling formulations utilizing input mappings, output mappings, frequency scaling and quadratic approximations. Our aim is to enhance circuit models for statistical analysis...... and yield-driven design. We illustrate our results using a capacitively-loaded two-section impedance transformer, a single-resonator waveguide filter and a six-section H-plane waveguide filter....

  19. A Trainable Spaced Repetition Model for Language Learning

    OpenAIRE

    Burr Settles; Brendan Meeder

    2017-01-01

    We present half-life regression (HLR), a novel model for spaced repetition practice with applications to second language acquisition. HLR combines psycholinguistic theory with modern machine learning techniques, indirectly estimating the “halflife” of a word or concept in a student’s long-term memory. We use data from Duolingo — a popular online language learning application — to fit HLR models, reducing error by 45%+ compared to several baselines at predicting student recall rates. HLR model...

  20. Space and Time Ontology: New Models for New Physics

    Directory of Open Access Journals (Sweden)

    Sara Lumbreras Sancho

    2015-02-01

    Full Text Available Nickel proposes a model for movement – and in general, for change – in which each instant in time (characterized as the set of real numbers is assigned to one point in a configuration space. As much as this model seems to intuitively fit to our experience, it implies a number of assumptions about the nature of space and time that are interesting to explore. Different perspectives have been developed across History, and it could well be that the next scientific revolution is set in motion by an innovative conception of space and time. One of this alternative perspectives was proposed by Julian Barbour, who has developed a new model of Physics where time does not exist [Barbour, 1999]. This paper reviews not only this concept but also other similarly provocative ideas that might prove useful for improving our understanding of the universe. Prior to this, the relevance of the philosophy of space and time will be briefly outlined and its history reviewed to provide some background for the discussed models. Finally, an approach where space and time are only defined by convention will be considered.

  1. Weight and the Future of Space Flight Hardware Cost Modeling

    Science.gov (United States)

    Prince, Frank A.

    2003-01-01

    Weight has been used as the primary input variable for cost estimating almost as long as there have been parametric cost models. While there are good reasons for using weight, serious limitations exist. These limitations have been addressed by multi-variable equations and trend analysis in models such as NAFCOM, PRICE, and SEER; however, these models have not be able to address the significant time lags that can occur between the development of similar space flight hardware systems. These time lags make the cost analyst's job difficult because insufficient data exists to perform trend analysis, and the current set of parametric models are not well suited to accommodating process improvements in space flight hardware design, development, build and test. As a result, people of good faith can have serious disagreement over the cost for new systems. To address these shortcomings, new cost modeling approaches are needed. The most promising approach is process based (sometimes called activity) costing. Developing process based models will require a detailed understanding of the functions required to produce space flight hardware combined with innovative approaches to estimating the necessary resources. Particularly challenging will be the lack of data at the process level. One method for developing a model is to combine notional algorithms with a discrete event simulation and model changes to the total cost as perturbations to the program are introduced. Despite these challenges, the potential benefits are such that efforts should be focused on developing process based cost models.

  2. High Resolution Space-Time Ozone Modeling for Assessing Trends.

    Science.gov (United States)

    Sahu, Sujit K; Gelfand, Alan E; Holland, David M

    2007-01-01

    The assessment of air pollution regulatory programs designed to improve ground level ozone concentrations is a topic of considerable interest to environmental managers. To aid this assessment, it is necessary to model the space-time behavior of ozone for predicting summaries of ozone across spatial domains of interest and for the detection of long-term trends at monitoring sites. These trends, adjusted for the effects of meteorological variables, are needed for determining the effectiveness of pollution control programs in terms of their magnitude and uncertainties across space. This paper proposes a space-time model for daily 8-hour maximum ozone levels to provide input to regulatory activities: detection, evaluation, and analysis of spatial patterns of ozone summaries and temporal trends. The model is applied to analyzing data from the state of Ohio which has been chosen because it contains a mix of urban, suburban, and rural ozone monitoring sites in several large cities separated by large rural areas. The proposed space-time model is auto-regressive and incorporates the most important meteorological variables observed at a collection of ozone monitoring sites as well as at several weather stations where ozone levels have not been observed. This problem of misalignment of ozone and meteorological data is overcome by spatial modeling of the latter. In so doing we adopt an approach based on the successive daily increments in meteorological variables. With regard to modeling, the increment (or change-in-meteorology) process proves more attractive than working directly with the meteorology process, without sacrificing any desired inference. The full model is specified within a Bayesian framework and is fitted using MCMC techniques. Hence, full inference with regard to model unknowns is available as well as for predictions in time and space, evaluation of annual summaries and assessment of trends.

  3. SpaceWire model development technology for satellite architecture.

    Energy Technology Data Exchange (ETDEWEB)

    Eldridge, John M.; Leemaster, Jacob Edward; Van Leeuwen, Brian P.

    2011-09-01

    Packet switched data communications networks that use distributed processing architectures have the potential to simplify the design and development of new, increasingly more sophisticated satellite payloads. In addition, the use of reconfigurable logic may reduce the amount of redundant hardware required in space-based applications without sacrificing reliability. These concepts were studied using software modeling and simulation, and the results are presented in this report. Models of the commercially available, packet switched data interconnect SpaceWire protocol were developed and used to create network simulations of data networks containing reconfigurable logic with traffic flows for timing system distribution.

  4. Extended Cellular Automata Models of Particles and Space-Time

    Science.gov (United States)

    Beedle, Michael

    2005-04-01

    Models of particles and space-time are explored through simulations and theoretical models that use Extended Cellular Automata models. The expanded Cellular Automata Models consist go beyond simple scalar binary cell-fields, into discrete multi-level group representations like S0(2), SU(2), SU(3), SPIN(3,1). The propagation and evolution of these expanded cellular automatas are then compared to quantum field theories based on the "harmonic paradigm" i.e. built by an infinite number of harmonic oscillators, and with gravitational models.

  5. Redshift space clustering of galaxies and cold dark matter model

    Science.gov (United States)

    Bahcall, Neta A.; Cen, Renyue; Gramann, Mirt

    1993-01-01

    The distorting effect of peculiar velocities on the power speturm and correlation function of IRAS and optical galaxies is studied. The observed redshift space power spectra and correlation functions of IRAS and optical the galaxies over the entire range of scales are directly compared with the corresponding redshift space distributions using large-scale computer simulations of cold dark matter (CDM) models in order to study the distortion effect of peculiar velocities on the power spectrum and correlation function of the galaxies. It is found that the observed power spectrum of IRAS and optical galaxies is consistent with the spectrum of an Omega = 1 CDM model. The problems that such a model currently faces may be related more to the high value of Omega in the model than to the shape of the spectrum. A low-density CDM model is also investigated and found to be consistent with the data.

  6. Requirements for modeling airborne microbial contamination in space stations

    Science.gov (United States)

    Van Houdt, Rob; Kokkonen, Eero; Lehtimäki, Matti; Pasanen, Pertti; Leys, Natalie; Kulmala, Ilpo

    2018-03-01

    Exposure to bioaerosols is one of the facets that affect indoor air quality, especially for people living in densely populated or confined habitats, and is associated to a wide range of health effects. Good indoor air quality is thus vital and a prerequisite for fully confined environments such as space habitats. Bioaerosols and microbial contamination in these confined space stations can have significant health impacts, considering the unique prevailing conditions and constraints of such habitats. Therefore, biocontamination in space stations is strictly monitored and controlled to ensure crew and mission safety. However, efficient bioaerosol control measures rely on solid understanding and knowledge on how these bioaerosols are created and dispersed, and which factors affect the survivability of the associated microorganisms. Here we review the current knowledge gained from relevant studies in this wide and multidisciplinary area of bioaerosol dispersion modeling and biological indoor air quality control, specifically taking into account the specific space conditions.

  7. Kane Method Based Dynamics Modeling and Control Study for Space Manipulator Capturing a Space Target

    Directory of Open Access Journals (Sweden)

    Yanhua Han

    2016-01-01

    Full Text Available Dynamics modeling and control problem of a two-link manipulator mounted on a spacecraft (so-called carrier freely flying around a space target on earth’s circular orbit is studied in the paper. The influence of the carrier’s relative movement on its manipulator is considered in dynamics modeling; nevertheless, that of the manipulator on its carrier is neglected with the assumption that the mass and inertia moment of the manipulator is far less than that of the carrier. Meanwhile, we suppose that the attitude control system of the carrier guarantees its side on which the manipulator is mounted points accurately always the space target during approaching operation. The ideal constraint forces can be out of consideration in dynamics modeling as Kane method is used. The path functions of the manipulator’s end-effector approaching the space target as well as the manipulator’s joints control torque functions are programmed to meet the soft touch requirement that the end-effector’s relative velocity to the space target is zero at touch moment. Numerical simulation validation is conducted finally.

  8. From Diagnosis to Action: An Automated Failure Advisor for Human Deep Space Missions

    Science.gov (United States)

    Colombano, Silvano; Spirkovska, Lilly; Baskaran, Vijayakumar; Morris, Paul; Mcdermott, William; Ossenfort, John; Bajwa, Anupa

    2015-01-01

    The major goal of current space system development at NASA is to enable human travel to deep space locations such as Mars and asteroids. At that distance, round trip communication with ground operators may take close to an hour, thus it becomes unfeasible to seek ground operator advice for problems that require immediate attention, either for crew safety or for activities that need to be performed at specific times for the attainment of scientific results. To achieve this goal, major reliance will need to be placed on automation systems capable of aiding the crew in detecting and diagnosing failures, assessing consequences of these failures, and providing guidance in repair activities that may be required. We report here on the most current step in the continuing development of such a system, and that is the addition of a Failure Response Advisor. In simple terms, we have a system in place the Advanced Caution and Warning System (ACAWS) to tell us what happened (failure diagnosis) and what happened because that happened (failure effects). The Failure Response Advisor will tell us what to do about it, how long until something must be done and why its important that something be done and will begin to approach the complex reasoning that is generally required for an optimal approach to automated system health management. This advice is based on the criticality and various timing elements, such as durations of activities and of component repairs, failure effects delay, and other factors. The failure advice is provided to operators (crew and mission controllers) together with the diagnostic and effects information. The operators also have the option to drill down for more information about the failure and the reasons for any suggested priorities.

  9. Sol-Terra - AN Operational Space Weather Forecasting Model Framework

    Science.gov (United States)

    Bisi, M. M.; Lawrence, G.; Pidgeon, A.; Reid, S.; Hapgood, M. A.; Bogdanova, Y.; Byrne, J.; Marsh, M. S.; Jackson, D.; Gibbs, M.

    2015-12-01

    The SOL-TERRA project is a collaboration between RHEA Tech, the Met Office, and RAL Space funded by the UK Space Agency. The goal of the SOL-TERRA project is to produce a Roadmap for a future coupled Sun-to-Earth operational space weather forecasting system covering domains from the Sun down to the magnetosphere-ionosphere-thermosphere and neutral atmosphere. The first stage of SOL-TERRA is underway and involves reviewing current models that could potentially contribute to such a system. Within a given domain, the various space weather models will be assessed how they could contribute to such a coupled system. This will be done both by reviewing peer reviewed papers, and via direct input from the model developers to provide further insight. Once the models have been reviewed then the optimal set of models for use in support of forecast-based SWE modelling will be selected, and a Roadmap for the implementation of an operational forecast-based SWE modelling framework will be prepared. The Roadmap will address the current modelling capability, knowledge gaps and further work required, and also the implementation and maintenance of the overall architecture and environment that the models will operate within. The SOL-TERRA project will engage with external stakeholders in order to ensure independently that the project remains on track to meet its original objectives. A group of key external stakeholders have been invited to provide their domain-specific expertise in reviewing the SOL-TERRA project at critical stages of Roadmap preparation; namely at the Mid-Term Review, and prior to submission of the Final Report. This stakeholder input will ensure that the SOL-TERRA Roadmap will be enhanced directly through the input of modellers and end-users. The overall goal of the SOL-TERRA project is to develop a Roadmap for an operational forecast-based SWE modelling framework with can be implemented within a larger subsequent activity. The SOL-TERRA project is supported within

  10. Modeling situated abstraction : action coalescence via multidimensional coherence.

    Energy Technology Data Exchange (ETDEWEB)

    Sallach, D. L.; Decision and Information Sciences; Univ. of Chicago

    2007-01-01

    Situated social agents weigh dozens of priorities, each with its own complexities. Domains of interest are intertwined, and progress in one area either complements or conflicts with other priorities. Interpretive agents address these complexities through: (1) integrating cognitive complexities through the use of radial concepts, (2) recognizing the role of emotion in prioritizing alternatives and urgencies, (3) using Miller-range constraints to avoid oversimplified notions omniscience, and (4) constraining actions to 'moves' in multiple prototype games. Situated agent orientations are dynamically grounded in pragmatic considerations as well as intertwined with internal and external priorities. HokiPoki is a situated abstraction designed to shape and focus strategic agent orientations. The design integrates four pragmatic pairs: (1) problem and solution, (2) dependence and power, (3) constraint and affordance, and (4) (agent) intent and effect. In this way, agents are empowered to address multiple facets of a situation in an exploratory, or even arbitrary, order. HokiPoki is open to the internal orientation of the agent as it evolves, but also to the communications and actions of other agents.

  11. A Cognitive Agent Model Incorporating Prior and Retrospective Ownership States for Actions

    NARCIS (Netherlands)

    Treur, J.; Walsh, T.

    2011-01-01

    The cognitive agent model presented in this paper generates prior and retrospective ownership states for an action based on principles from recent neurological theories. A prior ownership state is affected by prediction of the effects of a prepared action, and exerts control by strengthening or

  12. Trip and Control System Models in SPACE Code

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Ju; Park, Chan Eok; Lee, Gyu Cheon [Korea Power Engineering Company, Daejeon (Korea, Republic of)

    2009-05-15

    KOPEC has been developing a hydraulic solver of SPACE, which is a nuclear power plant safety analysis code, using two-fluid, three-field governing equations. Several numerical schemes, such as collocated, staggered, semi-implicit, and implicit schemes, have been tried so far. In this paper, the trip and control system model of SPACE will be described. The trip system of SPACE is developed to evaluate logical statements. Each trip statement is a simple logical statement that has a true or false result and an associated variable. The control system provides the capability to evaluate simultaneous algebraic and ordinary differential equations. The capability is primarily intended to simulate control systems typically used in nuclear reactor systems, but it can also model other phenomena described by algebraic and ordinary differential equations.

  13. Action semantics for defining dynamic semantics of modeling languages

    NARCIS (Netherlands)

    Stuurman, Gijs; Ivanov, Ivan

    Most languages in Model Driven Engineering (MDE) are defined by metamodels. Metamodels specify the structural aspects of models but do not capture the computational meaning of the modeling constructs (the dynamic semantics). There are several semantic definition frameworks used for programming

  14. Earth & Space Science in the Next Generation Science Standards: Promise, Challenge, and Future Actions. (Invited)

    Science.gov (United States)

    Pyle, E. J.

    2013-12-01

    The Next Generation Science Standards (NGSS) are a step forward in ensuring that future generations of students become scientifically literate. The NGSS document builds from the National Science Education Standards (1996) and the National Assessment of Educational Progress (NAEP) science framework of 2005. Design teams for the Curriculum Framework for K-12 Science Education were to outline the essential content necessary for students' science literacy, considering the foundational knowledge and the structure of each discipline in the context of learning progressions. Once draft standards were developed, two issues emerged from their review: (a) the continual need to prune 'cherished ideas' within the content, such that only essential ideas were represented, and (b) the potential for prior conceptions of Science & Engineering Practices (SEP) and cross-cutting concepts (CCC) to limit overly constrain performance expectations. With the release of the NGSS, several challenges are emerging for geoscience education. First, the traditional emphasis of Earth science in middle school has been augmented by new standards for high school that require major syntheses of concepts. Second, the integration of SEPs into performance expectations places an increased burden on teachers and curriculum developers to organize instruction around the nature of inquiry in the geosciences. Third, work is needed to define CCCs in Earth contexts, such that the unique structure of the geosciences is best represented. To ensure that the Earth & Space Science standards are implemented through grade 12, two supporting structures must be developed. In the past, many curricular materials claimed that they adhered to the NSES, but in some cases this match was a simple word match or checklist that bore only superficial resemblance to the standards. The structure of the performance expectations is of sufficient sophistication to ensure that adherence to the standards more than a casual exercise. Claims

  15. Joint space-time geostatistical model for air quality surveillance

    Science.gov (United States)

    Russo, A.; Soares, A.; Pereira, M. J.

    2009-04-01

    Air pollution and peoples' generalized concern about air quality are, nowadays, considered to be a global problem. Although the introduction of rigid air pollution regulations has reduced pollution from industry and power stations, the growing number of cars on the road poses a new pollution problem. Considering the characteristics of the atmospheric circulation and also the residence times of certain pollutants in the atmosphere, a generalized and growing interest on air quality issues led to research intensification and publication of several articles with quite different levels of scientific depth. As most natural phenomena, air quality can be seen as a space-time process, where space-time relationships have usually quite different characteristics and levels of uncertainty. As a result, the simultaneous integration of space and time is not an easy task to perform. This problem is overcome by a variety of methodologies. The use of stochastic models and neural networks to characterize space-time dispersion of air quality is becoming a common practice. The main objective of this work is to produce an air quality model which allows forecasting critical concentration episodes of a certain pollutant by means of a hybrid approach, based on the combined use of neural network models and stochastic simulations. A stochastic simulation of the spatial component with a space-time trend model is proposed to characterize critical situations, taking into account data from the past and a space-time trend from the recent past. To identify near future critical episodes, predicted values from neural networks are used at each monitoring station. In this paper, we describe the design of a hybrid forecasting tool for ambient NO2 concentrations in Lisbon, Portugal.

  16. Classical-to-quantum transition behavior between two oscillators separated in space under the action of optomechanical interaction.

    Science.gov (United States)

    Bai, Cheng-Hua; Wang, Dong-Yang; Wang, Hong-Fu; Zhu, Ai-Dong; Zhang, Shou

    2017-05-31

    We propose a scheme to show that the system consisting of two macroscopic oscillators separated in space which are coupled through Coulomb interaction displays the classical-to-quantum transition behavior under the action of optomechanical coupling interaction. Once the optomechanical coupling interaction disappears, the entanglement between the two separated oscillators disappears accordingly and the system will return to classical world even though there exists sufficiently strong Coulomb coupling between the oscillators. In addition, resorting to the squeezing of the cavity field generated by an optical parametric amplifier inside the cavity, we discuss the effect of squeezed light driving on this classical-to-quantum transition behavior instead of injecting the squeezed field directly. The results of numerical simulation show that the present scheme is feasible and practical and has stronger robustness against the environment temperature compared with previous schemes in current experimentally feasible regimes. The scheme might possibly help us to further clarify and grasp the classical-quantum boundary.

  17. Radiation Belt Environment Model: Application to Space Weather and Beyond

    Science.gov (United States)

    Fok, Mei-Ching H.

    2011-01-01

    Understanding the dynamics and variability of the radiation belts are of great scientific and space weather significance. A physics-based Radiation Belt Environment (RBE) model has been developed to simulate and predict the radiation particle intensities. The RBE model considers the influences from the solar wind, ring current and plasmasphere. It takes into account the particle drift in realistic, time-varying magnetic and electric field, and includes diffusive effects of wave-particle interactions with various wave modes in the magnetosphere. The RBE model has been used to perform event studies and real-time prediction of energetic electron fluxes. In this talk, we will describe the RBE model equation, inputs and capabilities. Recent advancement in space weather application and artificial radiation belt study will be discussed as well.

  18. Anatomical models for space radiation applications: an overview.

    Science.gov (United States)

    Atwell, W

    1994-10-01

    Extremely detailed computerized anatomical male (CAM) and female (CAF) models that have been developed for use in space radiation analyses are discussed and reviewed. Recognizing that the level of detail may currently be inadequate for certain radiological applications, one of the purposes of this paper is to elicit specific model improvements or requirements from the scientific user-community. Methods and rationale are presented which describe the approach used in the Space Shuttle program to extrapolate dosimetry measurements (skin doses) to realistic astronaut body organ doses. Several mission scenarios are presented which demonstrate the utility of the anatomical models for obtaining specific body organ exposure estimates and can be used for establishing cancer morbidity and mortality risk assessments. These exposure estimates are based on the trapped Van Allen belt and galactic cosmic radiation environment models and data from the major historical solar particle events.

  19. Redshift space bias and beta from the halo model

    OpenAIRE

    Seljak, Uros

    2000-01-01

    We analyze scale dependence of redshift space bias $b$ and $\\beta \\equiv \\Omega_m^{0.6}/b$ in the context of the halo model. We show that linear bias is a good approximation only on large scales, for $k

  20. Operationalizing the Space Weather Modeling Framework: Challenges and Resolutions

    Science.gov (United States)

    Welling, D. T.; Gombosi, T. I.; Toth, G.; Singer, H. J.; Millward, G. H.; Balch, C. C.; Cash, M. D.

    2016-12-01

    Predicting ground-based magnetic perturbations is a critical step towards specifying and predicting geomagnetically induced currents (GICs) in high voltage transmission lines. Currently, the Space Weather Modeling Framework (SWMF), a flexible modeling framework for simulating the multi-scale space environment, is being transitioned from research to operational use (R2O) by NOAA's Space Weather Prediction Center. Upon completion of this transition, the SWMF will provide localized time-varying magnetic field (dB/dt) predictions using real-time solar wind observations from L1 and the F10.7 proxy for EUV as model input. This presentation chronicles the challenges encountered during the R2O transition of the SWMF. Because operations relies on frequent calculations of global surface dB/dt, new optimizations were required to keep the model running faster than real time. Additionally, several singular situations arose during the 30-day robustness test that required immediate attention. Solutions and strategies for overcoming these issues will be presented. This includes new failsafe options for code execution, new physics and coupling parameters, and the development of an automated validation suite that allows us to monitor performance with code evolution. Finally, the operations-to-research (O2R) impact on SWMF-related research is presented. The lessons learned from this work are valuable and instructive for the space weather community as further R2O progress is made.

  1. Identification of structured LTI MIMO state-space models

    NARCIS (Netherlands)

    Yu, C.; Verhaegen, M.H.G.; Kovalsky, S; Basri, R; Valcher, ME; Ohta, Y; Sampei, M

    2015-01-01

    The identification of structured state-space model has been intensively studied for a long time but still has not been adequately addressed. The main challenge is that the involved estimation problem is a non-convex (or bilinear) optimization problem. This paper is devoted to developing an

  2. Modeling irregularly spaced residual series as a continuous stochastic process

    NARCIS (Netherlands)

    Von Asmuth, J.R.; Bierkens, M.F.P.

    2005-01-01

    In this paper, the background and functioning of a simple but effective continuous time approach for modeling irregularly spaced residual series is presented. The basic equations were published earlier by von Asmuth et al. (2002), who used them as part of a continuous time transfer function noise

  3. Magnetic Testing, and Modeling, Simulation and Analysis for Space Applications

    Science.gov (United States)

    Boghosian, Mary; Narvaez, Pablo; Herman, Ray

    2012-01-01

    The Aerospace Corporation (Aerospace) and Lockheed Martin Space Systems (LMSS) participated with Jet Propulsion Laboratory (JPL) in the implementation of a magnetic cleanliness program of the NASA/JPL JUNO mission. The magnetic cleanliness program was applied from early flight system development up through system level environmental testing. The JUNO magnetic cleanliness program required setting-up a specialized magnetic test facility at Lockheed Martin Space Systems for testing the flight system and a testing program with facility for testing system parts and subsystems at JPL. The magnetic modeling, simulation and analysis capability was set up and performed by Aerospace to provide qualitative and quantitative magnetic assessments of the magnetic parts, components, and subsystems prior to or in lieu of magnetic tests. Because of the sensitive nature of the fields and particles scientific measurements being conducted by the JUNO space mission to Jupiter, the imposition of stringent magnetic control specifications required a magnetic control program to ensure that the spacecraft's science magnetometers and plasma wave search coil were not magnetically contaminated by flight system magnetic interferences. With Aerospace's magnetic modeling, simulation and analysis and JPL's system modeling and testing approach, and LMSS's test support, the project achieved a cost effective approach to achieving a magnetically clean spacecraft. This paper presents lessons learned from the JUNO magnetic testing approach and Aerospace's modeling, simulation and analysis activities used to solve problems such as remnant magnetization, performance of hard and soft magnetic materials within the targeted space system in applied external magnetic fields.

  4. A Parametric Computational Model of the Action Potential of Pacemaker Cells.

    Science.gov (United States)

    Ai, Weiwei; Patel, Nitish D; Roop, Partha S; Malik, Avinash; Andalam, Sidharta; Yip, Eugene; Allen, Nathan; Trew, Mark L

    2018-01-01

    A flexible, efficient, and verifiable pacemaker cell model is essential to the design of real-time virtual hearts that can be used for closed-loop validation of cardiac devices. A new parametric model of pacemaker action potential is developed to address this need. The action potential phases are modeled using hybrid automaton with one piecewise-linear continuous variable. The model can capture rate-dependent dynamics, such as action potential duration restitution, conduction velocity restitution, and overdrive suppression by incorporating nonlinear update functions. Simulated dynamics of the model compared well with previous models and clinical data. The results show that the parametric model can reproduce the electrophysiological dynamics of a variety of pacemaker cells, such as sinoatrial node, atrioventricular node, and the His-Purkinje system, under varying cardiac conditions. This is an important contribution toward closed-loop validation of cardiac devices using real-time heart models.

  5. Space in multi-agent systems modelling spatial processes

    Directory of Open Access Journals (Sweden)

    Petr Rapant

    2007-06-01

    Full Text Available Need for modelling of spatial processes arise in the spehere of geoinformation systems in the last time. Some processes (espetially natural ones can be modeled by means of using external tools, e. g. for modelling of contaminant transport in the environment. But in the case of socio-economic processes suitable tools interconnected with GIS are still in quest of reserch and development. One of the candidate technologies are so called multi-agent systems. Their theory is developed quite well, but they lack suitable means for dealing with space. This article deals with this problem and proposes solution for the field of a road transport modelling.

  6. Applying Model Based Systems Engineering to NASA's Space Communications Networks

    Science.gov (United States)

    Bhasin, Kul; Barnes, Patrick; Reinert, Jessica; Golden, Bert

    2013-01-01

    System engineering practices for complex systems and networks now require that requirement, architecture, and concept of operations product development teams, simultaneously harmonize their activities to provide timely, useful and cost-effective products. When dealing with complex systems of systems, traditional systems engineering methodology quickly falls short of achieving project objectives. This approach is encumbered by the use of a number of disparate hardware and software tools, spreadsheets and documents to grasp the concept of the network design and operation. In case of NASA's space communication networks, since the networks are geographically distributed, and so are its subject matter experts, the team is challenged to create a common language and tools to produce its products. Using Model Based Systems Engineering methods and tools allows for a unified representation of the system in a model that enables a highly related level of detail. To date, Program System Engineering (PSE) team has been able to model each network from their top-level operational activities and system functions down to the atomic level through relational modeling decomposition. These models allow for a better understanding of the relationships between NASA's stakeholders, internal organizations, and impacts to all related entities due to integration and sustainment of existing systems. Understanding the existing systems is essential to accurate and detailed study of integration options being considered. In this paper, we identify the challenges the PSE team faced in its quest to unify complex legacy space communications networks and their operational processes. We describe the initial approaches undertaken and the evolution toward model based system engineering applied to produce Space Communication and Navigation (SCaN) PSE products. We will demonstrate the practice of Model Based System Engineering applied to integrating space communication networks and the summary of its

  7. Dynamic State Space Partitioning for External Memory Model Checking

    DEFF Research Database (Denmark)

    Evangelista, Sami; Kristensen, Lars Michael

    2009-01-01

    We describe a dynamic partitioning scheme usable by model checking techniques that divide the state space into partitions, such as most external memory and distributed model checking algorithms. The goal of the scheme is to reduce the number of transitions that link states belonging to different ...... partitions, and thereby limit the amount of disk access and network communication. We report on several experiments made with our verification platform ASAP that implements the dynamic partitioning scheme proposed in this paper....

  8. Constructing Experience: Event Models from Perception to Action.

    Science.gov (United States)

    Richmond, Lauren L; Zacks, Jeffrey M

    2017-12-01

    Mental representations of everyday experience are rich, structured, and multimodal. In this article we consider the adaptive pressures that led to human construction of such representations, arguing that structured event representations enable cognitive systems to more effectively predict the trajectory of naturalistic everyday activity. We propose an account of how cortical systems and the hippocampus (HPC) interact to construct, maintain, and update event representations. This analysis throws light on recent research on story comprehension, event segmentation, episodic memory, and action planning. It also suggests how the growing science base can be deployed to diagnose impairments in event perception and memory, and to improve memory for everyday events. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. A Management Model for International Participation in Space Exploration Missions

    Science.gov (United States)

    George, Patrick J.; Pease, Gary M.; Tyburski, Timothy E.

    2005-01-01

    This paper proposes an engineering management model for NASA's future space exploration missions based on past experiences working with the International Partners of the International Space Station. The authors have over 25 years of combined experience working with the European Space Agency, Japan Aerospace Exploration Agency, Canadian Space Agency, Italian Space Agency, Russian Space Agency, and their respective contractors in the design, manufacturing, verification, and integration of their elements electric power system into the United States on-orbit segment. The perspective presented is one from a specific sub-system integration role and is offered so that the lessons learned from solving issues of technical and cultural nature may be taken into account during the formulation of international partnerships. Descriptions of the types of unique problems encountered relative to interactions between international partnerships are reviewed. Solutions to the problems are offered, taking into consideration the technical implications. Through the process of investigating each solution, the important and significant issues associated with working with international engineers and managers are outlined. Potential solutions are then characterized by proposing a set of specific methodologies to jointly develop spacecraft configurations that benefits all international participants, maximizes mission success and vehicle interoperability while minimizing cost.

  10. Optimisation of ionic models to fit tissue action potentials: application to 3D atrial modelling.

    Science.gov (United States)

    Al Abed, Amr; Guo, Tianruo; Lovell, Nigel H; Dokos, Socrates

    2013-01-01

    A 3D model of atrial electrical activity has been developed with spatially heterogeneous electrophysiological properties. The atrial geometry, reconstructed from the male Visible Human dataset, included gross anatomical features such as the central and peripheral sinoatrial node (SAN), intra-atrial connections, pulmonary veins, inferior and superior vena cava, and the coronary sinus. Membrane potentials of myocytes from spontaneously active or electrically paced in vitro rabbit cardiac tissue preparations were recorded using intracellular glass microelectrodes. Action potentials of central and peripheral SAN, right and left atrial, and pulmonary vein myocytes were each fitted using a generic ionic model having three phenomenological ionic current components: one time-dependent inward, one time-dependent outward, and one leakage current. To bridge the gap between the single-cell ionic models and the gross electrical behaviour of the 3D whole-atrial model, a simplified 2D tissue disc with heterogeneous regions was optimised to arrive at parameters for each cell type under electrotonic load. Parameters were then incorporated into the 3D atrial model, which as a result exhibited a spontaneously active SAN able to rhythmically excite the atria. The tissue-based optimisation of ionic models and the modelling process outlined are generic and applicable to image-based computer reconstruction and simulation of excitable tissue.

  11. Optimisation of Ionic Models to Fit Tissue Action Potentials: Application to 3D Atrial Modelling

    Science.gov (United States)

    Lovell, Nigel H.; Dokos, Socrates

    2013-01-01

    A 3D model of atrial electrical activity has been developed with spatially heterogeneous electrophysiological properties. The atrial geometry, reconstructed from the male Visible Human dataset, included gross anatomical features such as the central and peripheral sinoatrial node (SAN), intra-atrial connections, pulmonary veins, inferior and superior vena cava, and the coronary sinus. Membrane potentials of myocytes from spontaneously active or electrically paced in vitro rabbit cardiac tissue preparations were recorded using intracellular glass microelectrodes. Action potentials of central and peripheral SAN, right and left atrial, and pulmonary vein myocytes were each fitted using a generic ionic model having three phenomenological ionic current components: one time-dependent inward, one time-dependent outward, and one leakage current. To bridge the gap between the single-cell ionic models and the gross electrical behaviour of the 3D whole-atrial model, a simplified 2D tissue disc with heterogeneous regions was optimised to arrive at parameters for each cell type under electrotonic load. Parameters were then incorporated into the 3D atrial model, which as a result exhibited a spontaneously active SAN able to rhythmically excite the atria. The tissue-based optimisation of ionic models and the modelling process outlined are generic and applicable to image-based computer reconstruction and simulation of excitable tissue. PMID:23935704

  12. Optimisation of Ionic Models to Fit Tissue Action Potentials: Application to 3D Atrial Modelling

    Directory of Open Access Journals (Sweden)

    Amr Al Abed

    2013-01-01

    Full Text Available A 3D model of atrial electrical activity has been developed with spatially heterogeneous electrophysiological properties. The atrial geometry, reconstructed from the male Visible Human dataset, included gross anatomical features such as the central and peripheral sinoatrial node (SAN, intra-atrial connections, pulmonary veins, inferior and superior vena cava, and the coronary sinus. Membrane potentials of myocytes from spontaneously active or electrically paced in vitro rabbit cardiac tissue preparations were recorded using intracellular glass microelectrodes. Action potentials of central and peripheral SAN, right and left atrial, and pulmonary vein myocytes were each fitted using a generic ionic model having three phenomenological ionic current components: one time-dependent inward, one time-dependent outward, and one leakage current. To bridge the gap between the single-cell ionic models and the gross electrical behaviour of the 3D whole-atrial model, a simplified 2D tissue disc with heterogeneous regions was optimised to arrive at parameters for each cell type under electrotonic load. Parameters were then incorporated into the 3D atrial model, which as a result exhibited a spontaneously active SAN able to rhythmically excite the atria. The tissue-based optimisation of ionic models and the modelling process outlined are generic and applicable to image-based computer reconstruction and simulation of excitable tissue.

  13. Ultracapacitor Modelling and Control Using Discrete Fractional Order State-Space Model

    Directory of Open Access Journals (Sweden)

    Andrzej Dzielinski

    2008-03-01

    Full Text Available In this paper the modelling of ultracapacitor system using discrete fractional order state-space system is presented. The obtained model is used for design and testing of state feedback controller with observer.

  14. Teachers’ individual action theories about competence-based education: the value of the cognitive apprenticeship model

    NARCIS (Netherlands)

    Seezink, Audrey; Poell, Rob; Kirschner, Paul A.

    2009-01-01

    Seezink, A., Poell, R. F., & Kirschner, P. A. (2009). Teachers' individual action theories about competence-based education: The value of the cognitive apprenticeship model. Journal of Vocational Education & Training, 61, 203-215.

  15. Groundwater modelling in conceptual hydrological models - introducing space

    Science.gov (United States)

    Boje, Søren; Skaugen, Thomas; Møen, Knut; Myrabø, Steinar

    2017-04-01

    The tiny Sæternbekken Minifelt (Muren) catchment (7500 m2) in Bærumsmarka, Norway, was during the 1990s, densely instrumented with more than a 100 observation points for measuring groundwater levels. The aim was to investigate the link between shallow groundwater dynamics and runoff. The DDD (Distance Distribution Dynamics) model is a newly developed rainfall-runoff model used operationally by the Norwegian Flood-Forecasting service at NVE. The model estimates the capacity of the subsurface reservoir at different levels of saturation and predicts overland flow. The subsurface in the DDD model has a 2-D representation that calculates the saturated and unsaturated soil moisture along a hillslope representing the entire catchment in question. The groundwater observations from more than two decades ago are used to verify assumptions of the subsurface reservoir in the DDD model and to validate its spatial representation of the subsurface reservoir. The Muren catchment will, during 2017, be re-instrumented in order to continue the work to bridge the gap between conceptual hydrological models, with typically single value or 0-dimension representation of the subsurface, and models with more realistic 2- or 3-dimension representation of the subsurface.

  16. Data and models in Action. Methodological Issues in Production Ecology

    NARCIS (Netherlands)

    Stein, A.; Penning, de F.W.T.

    1999-01-01

    This book addresses methodological issues of production ecology. A central issue is the combination of the agricultural model with reliable data in relation to scale. A model is developed with data from a single point, whereas decisions are to be made for areas of land. Such an approach requires the

  17. Space modeling with SolidWorks and NX

    CERN Document Server

    Duhovnik, Jože; Drešar, Primož

    2015-01-01

    Through a series of step-by-step tutorials and numerous hands-on exercises, this book aims to equip the reader with both a good understanding of the importance of space in the abstract world of engineers and the ability to create a model of a product in virtual space – a skill essential for any designer or engineer who needs to present ideas concerning a particular product within a professional environment. The exercises progress logically from the simple to the more complex; while SolidWorks or NX is the software used, the underlying philosophy is applicable to all modeling software. In each case, the explanation covers the entire procedure from the basic idea and production capabilities through to the real model; the conversion from 3D model to 2D manufacturing drawing is also clearly explained. Topics covered include modeling of prism, axisymmetric, symmetric, and sophisticated shapes; digitization of physical models using modeling software; creation of a CAD model starting from a physical model; free fo...

  18. State space modeling of Memristor-based Wien oscillator

    KAUST Repository

    Talukdar, Abdul Hafiz Ibne

    2011-12-01

    State space modeling of Memristor based Wien \\'A\\' oscillator has been demonstrated for the first time considering nonlinear ion drift in Memristor. Time dependant oscillating resistance of Memristor is reported in both state space solution and SPICE simulation which plausibly provide the basis of realizing parametric oscillation by Memristor based Wien oscillator. In addition to this part Memristor is shown to stabilize the final oscillation amplitude by means of its nonlinear dynamic resistance which hints for eliminating diode in the feedback network of conventional Wien oscillator. © 2011 IEEE.

  19. Life sciences research in space: The requirement for animal models

    Science.gov (United States)

    Fuller, C. A.; Philips, R. W.; Ballard, R. W.

    1987-01-01

    Use of animals in NASA space programs is reviewed. Animals are needed because life science experimentation frequently requires long-term controlled exposure to environments, statistical validation, invasive instrumentation or biological tissue sampling, tissue destruction, exposure to dangerous or unknown agents, or sacrifice of the subject. The availability and use of human subjects inflight is complicated by the multiple needs and demands upon crew time. Because only living organisms can sense, integrate and respond to the environment around them, the sole use of tissue culture and computer models is insufficient for understanding the influence of the space environment on intact organisms. Equipment for spaceborne experiments with animals is described.

  20. The Challenge of Configuring Model-Based Space Mission Planners

    Science.gov (United States)

    Frank, Jeremy D.; Clement, Bradley J.; Chachere, John M.; Smith, Tristan B.; Swanson, Keith J.

    2011-01-01

    Mission planning is central to space mission operations, and has benefited from advances in model-based planning software. Constraints arise from many sources, including simulators and engineering specification documents, and ensuring that constraints are correctly represented in the planner is a challenge. As mission constraints evolve, planning domain modelers need help with modeling constraints efficiently using the available source data, catching errors quickly, and correcting the model. This paper describes the current state of the practice in designing model-based mission planning tools, the challenges facing model developers, and a proposed Interactive Model Development Environment (IMDE) to configure mission planning systems. We describe current and future technology developments that can be integrated into an IMDE.

  1. Formulating state space models in R with focus on longitudinal regression models

    DEFF Research Database (Denmark)

    Dethlefsen, Claus; Lundbye-Christensen, Søren

    in the formula. However, the model definition and the model fit are separated in different calls. The model definition creates an object with a number of associated functions. The model object may be edited to incorporate extra features before it is fitted to data. The formulation of models does not depend......  We provide a language for formulating a range of state space models. The described methodology is implemented in the R -package sspir available from cran.r-project.org . A state space model is specified similarly to a generalized linear model in R , by marking the time-varying terms...

  2. Requirements for modeling and simulation of space RSTA assets

    Science.gov (United States)

    Livingston, Raymond L., Jr.

    2004-09-01

    The Department of Defense (DoD) has long depended on military support functions enabled by space reconnaissance, surveillance, and target acquisition (RSTA) assets. Future generation satellite capabilities will further push technologies in space - if the right technologies are deployed in the right numbers and with the right payloads. Modeling and simulation play major parts in developing and deploying such assets: 1) system and operational requirements determination, and 2) assessment of military utility of such assets. Each area is critical in a system"s life cycle. Requirements determination cuts across the issues of doctrine, organizations, training, materiel, leader development, personnel, and facilities (DOTMLPF). Military utility assessments are necessary to explore and quantify the military worth/benefit of space RSTA assets to operational commanders. Each of these areas requires relevant modeling/simulation tools which span the engineering to system to operational levels. Appropriate assessments of space with related air and ground RSTA assets. This paper will discuss some of the modeling and simulation requirements to address the above issues.

  3. Extracting Actionability from Machine Learning Models by Sub-optimal Deterministic Planning

    OpenAIRE

    Lyu, Qiang; Chen, Yixin; Li, Zhaorong; Cui, Zhicheng; Chen, Ling; Zhang, Xing; Shen, Haihua

    2016-01-01

    A main focus of machine learning research has been improving the generalization accuracy and efficiency of prediction models. Many models such as SVM, random forest, and deep neural nets have been proposed and achieved great success. However, what emerges as missing in many applications is actionability, i.e., the ability to turn prediction results into actions. For example, in applications such as customer relationship management, clinical prediction, and advertisement, the users need not on...

  4. A State Space Model for the Wood Chip Refining Model

    Directory of Open Access Journals (Sweden)

    David Di Ruscio

    1997-07-01

    Full Text Available A detailed dynamic model of the fibre size distribution between the refiner discs, distributed along the refiner radius, is presented. Both one- and two-dimensional descriptions for the fibre or shive geometry are given. It is shown that this model may be simplified and that analytic solutions exist under non-restrictive assumptions. A direct method for the recursive estimation of unknown parameters is presented. This method is applicable to linear or linearized systems which have a triangular structure.

  5. A growing social network model in geographical space

    Science.gov (United States)

    Antonioni, Alberto; Tomassini, Marco

    2017-09-01

    In this work we propose a new model for the generation of social networks that includes their often ignored spatial aspects. The model is a growing one and links are created either taking space into account, or disregarding space and only considering the degree of target nodes. These two effects can be mixed linearly in arbitrary proportions through a parameter. We numerically show that for a given range of the combination parameter, and for given mean degree, the generated network class shares many important statistical features with those observed in actual social networks, including the spatial dependence of connections. Moreover, we show that the model provides a good qualitative fit to some measured social networks.

  6. Combined Hand Gesture — Speech Model for Human Action Recognition

    Science.gov (United States)

    Cheng, Sheng-Tzong; Hsu, Chih-Wei; Li, Jian-Pan

    2013-01-01

    This study proposes a dynamic hand gesture detection technology to effectively detect dynamic hand gesture areas, and a hand gesture recognition technology to improve the dynamic hand gesture recognition rate. Meanwhile, the corresponding relationship between state sequences in hand gesture and speech models is considered by integrating speech recognition technology with a multimodal model, thus improving the accuracy of human behavior recognition. The experimental results proved that the proposed method can effectively improve human behavior recognition accuracy and the feasibility of system applications. Experimental results verified that the multimodal gesture-speech model provided superior accuracy when compared to the single modal versions. PMID:24351628

  7. Mental Models and the Control of Actions in Complex Environments

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1987-01-01

    of human activities. The need for analysis of complex work scenarios is discussed, together with the necessity of considering several levels of cognitive control depending upon different kinds of internal representations. The development of mental representations during learning and adaptation......The concept of mental models has become an important ingredient in models of the cognitive control of human behaviour. The paper reviews different approaches to the definition of mental models taken in psychology and cognitive sciences, which typically have been considering selected aspects...

  8. State-space modeling to support management of brucellosis in the Yellowstone bison population

    Science.gov (United States)

    Hobbs, N. Thompson; Geremia, Chris; Treanor, John; Wallen, Rick; White, P.J.; Hooten, Mevin B.; Rhyan, Jack C.

    2015-01-01

    The bison (Bison bison) of the Yellowstone ecosystem, USA, exemplify the difficulty of conserving large mammals that migrate across the boundaries of conservation areas. Bison are infected with brucellosis (Brucella abortus) and their seasonal movements can expose livestock to infection. Yellowstone National Park has embarked on a program of adaptive management of bison, which requires a model that assimilates data to support management decisions. We constructed a Bayesian state-space model to reveal the influence of brucellosis on the Yellowstone bison population. A frequency-dependent model of brucellosis transmission was superior to a density-dependent model in predicting out-of-sample observations of horizontal transmission probability. A mixture model including both transmission mechanisms converged on frequency dependence. Conditional on the frequency-dependent model, brucellosis median transmission rate was 1.87 yr−1. The median of the posterior distribution of the basic reproductive ratio (R0) was 1.75. Seroprevalence of adult females varied around 60% over two decades, but only 9.6 of 100 adult females were infectious. Brucellosis depressed recruitment; estimated population growth rate λ averaged 1.07 for an infected population and 1.11 for a healthy population. We used five-year forecasting to evaluate the ability of different actions to meet management goals relative to no action. Annually removing 200 seropositive female bison increased by 30-fold the probability of reducing seroprevalence below 40% and increased by a factor of 120 the probability of achieving a 50% reduction in transmission probability relative to no action. Annually vaccinating 200 seronegative animals increased the likelihood of a 50% reduction in transmission probability by fivefold over no action. However, including uncertainty in the ability to implement management by representing stochastic variation in the number of accessible bison dramatically reduced the probability of

  9. Space physiology IV: mathematical modeling of the cardiovascular system in space exploration.

    Science.gov (United States)

    Keith Sharp, M; Batzel, Jerry Joseph; Montani, Jean-Pierre

    2013-08-01

    Mathematical modeling represents an important tool for analyzing cardiovascular function during spaceflight. This review describes how modeling of the cardiovascular system can contribute to space life science research and illustrates this process via modeling efforts to study postflight orthostatic intolerance (POI), a key issue for spaceflight. Examining this application also provides a context for considering broader applications of modeling techniques to the challenges of bioastronautics. POI, which affects a large fraction of astronauts in stand tests upon return to Earth, presents as dizziness, fainting and other symptoms, which can diminish crew performance and cause safety hazards. POI on the Moon or Mars could be more critical. In the field of bioastronautics, POI has been the dominant application of cardiovascular modeling for more than a decade, and a number of mechanisms for POI have been investigated. Modeling approaches include computational models with a range of incorporated factors and hemodynamic sophistication, and also physical models tested in parabolic and orbital flight. Mathematical methods such as parameter sensitivity analysis can help identify key system mechanisms. In the case of POI, this could lead to more effective countermeasures. Validation is a persistent issue in modeling efforts, and key considerations and needs for experimental data to synergistically improve understanding of cardiovascular responses are outlined. Future directions in cardiovascular modeling include subject-specific assessment of system status, as well as research on integrated physiological responses, leading, for instance, to assessment of subject-specific susceptibility to POI or effects of cardiovascular alterations on muscular, vision and cognitive function.

  10. Rodent Models of Non-classical Progesterone Action Regulating Ovulation

    Directory of Open Access Journals (Sweden)

    Melinda A. Mittelman-Smith

    2017-07-01

    Full Text Available It is becoming clear that steroid hormones act not only by binding to nuclear receptors that associate with specific response elements in the nucleus but also by binding to receptors on the cell membrane. In this newly discovered manner, steroid hormones can initiate intracellular signaling cascades which elicit rapid effects such as release of internal calcium stores and activation of kinases. We have learned much about the translocation and signaling of steroid hormone receptors from investigations into estrogen receptor α, which can be trafficked to, and signal from, the cell membrane. It is now clear that progesterone (P4 can also elicit effects that cannot be exclusively explained by transcriptional changes. Similar to E2 and its receptors, P4 can initiate signaling at the cell membrane, both through progesterone receptor and via a host of newly discovered membrane receptors (e.g., membrane progesterone receptors, progesterone receptor membrane components. This review discusses the parallels between neurotransmitter-like E2 action and the more recently investigated non-classical P4 signaling, in the context of reproductive behaviors in the rodent.

  11. Relativistic Superdense Star Models of Pseudo Spheroidal Space-Time

    Science.gov (United States)

    Tikekar, Ramesh; Jotania, Kanti

    The physically viable models of compact stars like SAX (J1808.4-3658) can be obtained using Vaidya-Tikekar ansatz prescribing spheroidal geometry for their interior space-time. We discuss here the suitability of an alternative ansatz in this context. The models of superdense star are proposed using a general three parameter family of solutions of relativistic field equations obtained adopting the alternative ansatz. The setup is shown to admit physically viable models of superdense stars and strange matter stars such as Her. X-1.

  12. Acting in solidarity: Testing an extended dual pathway model of collective action by bystander group members.

    Science.gov (United States)

    Saab, Rim; Tausch, Nicole; Spears, Russell; Cheung, Wing-Yee

    2015-09-01

    We examined predictors of collective action among bystander group members in solidarity with a disadvantaged group by extending the dual pathway model of collective action, which proposes one efficacy-based and one emotion-based path to collective action (Van Zomeren, Spears, Fischer, & Leach, 2004). Based on two proposed functions of social identity performance (Klein, Spears, & Reicher, 2007), we distinguished between the efficacy of collective action at consolidating the identity of a protest movement and its efficacy at achieving social change (political efficacy). We expected identity consolidation efficacy to positively predict collective action tendencies directly and indirectly via political efficacy. We also expected collective action tendencies to be positively predicted by moral outrage and by sympathy in response to disadvantaged outgroup's suffering. These hypotheses were supported in two surveys examining intentions to protest for Palestine in Britain (Study 1), and intentions to attend the June 4th vigil in Hong Kong to commemorate the Tiananmen massacre among a sample of Hong Kong citizens (Study 2). The contributions of these findings to research on the dual pathway model of collective action and the different functions of collective action are discussed. © 2014 The British Psychological Society.

  13. Stirling System Modeling for Space Nuclear Power Systems

    Science.gov (United States)

    Lewandowski, Edward J.; Johnson, Paul K.

    2008-01-01

    A dynamic model of a high-power Stirling convertor has been developed for space nuclear power systems modeling. The model is based on the Component Test Power Convertor (CTPC), a 12.5-kWe free-piston Stirling convertor. The model includes the fluid heat source, the Stirling convertor, output power, and heat rejection. The Stirling convertor model includes the Stirling cycle thermodynamics, heat flow, mechanical mass-spring damper systems, and the linear alternator. The model was validated against test data. Both nonlinear and linear versions of the model were developed. The linear version algebraically couples two separate linear dynamic models; one model of the Stirling cycle and one model of the thermal system, through the pressure factors. Future possible uses of the Stirling system dynamic model are discussed. A pair of commercially available 1-kWe Stirling convertors is being purchased by NASA Glenn Research Center. The specifications of those convertors may eventually be incorporated into the dynamic model and analysis compared to the convertor test data. Subsequent potential testing could include integrating the convertors into a pumped liquid metal hot-end interface. This test would provide more data for comparison to the dynamic model analysis.

  14. Real-time logic modelling on SpaceWire

    Science.gov (United States)

    Zhou, Qiang; Ma, Yunpeng; Fei, Haidong; Wang, Xingyou

    2017-04-01

    A SpaceWire is a standard for on-board satellite networks as the basis for future data-handling architectures. However, it cannot meet the deterministic requirement for safety/time critical application in spacecraft, where the delay of real-time (RT) message streams must be guaranteed. Therefore, SpaceWire-D is developed that provides deterministic delivery over a SpaceWire network. Formal analysis and verification of real-time systems is critical to their development and safe implementation, and is a prerequisite for obtaining their safety certification. Failure to meet specified timing constraints such as deadlines in hard real-time systems may lead to catastrophic results. In this paper, a formal verification method, Real-Time Logic (RTL), has been proposed to specify and verify timing properties of SpaceWire-D network. Based on the principal of SpaceWire-D protocol, we firstly analyze the timing properties of fundamental transactions, such as RMAP WRITE, and RMAP READ. After that, the RMAP WRITE transaction structure is modeled in Real-Time Logic (RTL) and Presburger Arithmetic representations. And then, the associated constraint graph and safety analysis is provided. Finally, it is suggested that RTL method can be useful for the protocol evaluation and provision of recommendation for further protocol evolutions.

  15. A New SPACE Modeling Method for FD-SIT

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In-Hun; Choi, Tong-Soo; Lee, Jae Il [KEPCO NF, Daejeon (Korea, Republic of)

    2015-10-15

    At start SIT water level is higher than the top of the stand pipe, and hence the injection takes place through two channels. When SIT water level becomes below the top of the stand pipe, the water flows into 4 control ports resulting in relatively high flow resistance through the control ports. It renders the decrease of the injection flow rate and extends the SIT water injection time. The SPACE code may model a SIT using the SIT component composed of one CELL and one FACE. In this case, however, fluid movement inside the tank can not be predicted reasonably and the nitrogen gas release is allowed only when the tank becomes empty. To predict realistically the nitrogen gas release from SITs, a new SIT modeling method has been developed. In this method, normal hydraulic components such as CELL, FACE, PIPE and BRCH are used instead of the SIT component to simulate the water and gas flow inside the tank. The new method has been validated against the VAPER tests and the pre-operation blowdown tests conducted in Shin-Kori Unit 3. In this paper, for the purpose of LBLOCA analysis of Shin-Kori units 3 and 4, SPACE modelling method for SIT with FD was developed. And its applicability and effect has been evaluated. The SPACE inputs were developed for nitrogen gas release and SIT to be realistically modeled.

  16. Framework for the Parametric System Modeling of Space Exploration Architectures

    Science.gov (United States)

    Komar, David R.; Hoffman, Jim; Olds, Aaron D.; Seal, Mike D., II

    2008-01-01

    This paper presents a methodology for performing architecture definition and assessment prior to, or during, program formulation that utilizes a centralized, integrated architecture modeling framework operated by a small, core team of general space architects. This framework, known as the Exploration Architecture Model for IN-space and Earth-to-orbit (EXAMINE), enables: 1) a significantly larger fraction of an architecture trade space to be assessed in a given study timeframe; and 2) the complex element-to-element and element-to-system relationships to be quantitatively explored earlier in the design process. Discussion of the methodology advantages and disadvantages with respect to the distributed study team approach typically used within NASA to perform architecture studies is presented along with an overview of EXAMINE s functional components and tools. An example Mars transportation system architecture model is used to demonstrate EXAMINE s capabilities in this paper. However, the framework is generally applicable for exploration architecture modeling with destinations to any celestial body in the solar system.

  17. A continuum model for dynamic analysis of the Space Station

    Science.gov (United States)

    Thomas, Segun

    1989-01-01

    Dynamic analysis of the International Space Station using MSC/NASTRAN had 1312 rod elements, 62 beam elements, 489 nodes and 1473 dynamic degrees of freedom. A realtime, man-in-the-loop simulation of such a model is impractical. This paper discusses the mathematical model for realtime dynamic simulation of the Space Station. Several key questions in structures and structural dynamics are addressed. First, to achieve a significant reduction in the number of dynamic degrees of freedom, a continuum equivalent representation of the Space Station truss structure which accounted for the unsymmetry of the basic configuration and resulted in the coupling of extensional and transverse deformation, is developed. Next, dynamic equations for the continuum equivalent of the Space Station truss structure are formulated using a matrix version of Kane's dynamical equations. Flexibility is accounted for by using a theory that accommodates extension, bending in two principal planes and shear displacement. Finally, constraint equations suitable for dynamic analysis of flexible bodies with closed loop configuration are developed and solution of the resulting system of equations is based on the zero eigenvalue theorem.

  18. Modeling and Capturing Users’ Actions in CSCL Systems for Collaboration Analysis Purposes

    Directory of Open Access Journals (Sweden)

    Manuel Ortega

    2009-03-01

    Full Text Available A significant number of CSCL (Computer-Supported Collaborative Learning environments support the learning of groups of students enabling their collaboration in solving problems. These collaborative environments usually need additional computational support to allow the automatic processing of both the actions carried out by the students and the end solution with the aim of studying the learning process and the validity of the solution proposed to the problem. This process, known as Collaboration and Interaction Analysis, is typically carried out in three phases: observation, abstraction and intervention. In this paper, we propose a methodological approach for the design of mechanisms for the observation phase. This approach provides a set of procedures enabling developers to design observation systems in CSCL environments that capture and model all the information required for comprehensive analyses of the collaboration process and the resulting solution to the problem. This methodological approach is put into practice by means of its use in the design of an observation system in the SPACE-DESIGN (SPecification and Automatic Construction of collaborative Environments of DESIGN collaborative environment.

  19. Enhancing the Action Research Capacity of the International Model ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    This project will continue IDRC's commitment to and involvement in the IMFN by supporting IMFN operating expenses, governance bodies, committee work, grants to individual model forests, communications and outreach, knowledge management, and strategic initiatives. It is expected that by the end of the project, the ...

  20. Teachers' Practices and Mental Models: Transformation through Reflection on Action

    Science.gov (United States)

    Manrique, María Soledad; Sánchez Abchi, Verónica

    2015-01-01

    This contribution explores the relationship between teaching practices, teaching discourses and teachers' implicit representations and mental models and the way these dimensions change through teacher education (T.E). In order to study these relationships, and based on the assumptions that representations underlie teaching practices and that T.E…

  1. Characteristics of Effective Training: Developing a Model To Motivate Action.

    Science.gov (United States)

    Wise, Dena; Ezell, Patsy

    2003-01-01

    The Parenting and Consumer Education project identified effective models for training welfare-to-work facilitators. Premises were the importance of process, learner responsibility, and improvement of social networks. Effective training was learner focused, inspiring, and motivating; demonstrated productive behaviors and effective life skills; and…

  2. Dynamical 3-Space Gravity Theory: Effects on Polytropic Solar Models

    Directory of Open Access Journals (Sweden)

    May R. D.

    2011-01-01

    Full Text Available Numerous experiments and observations have confirmed the existence of a dynamical 3-space, detectable directly by light-speed anisotropy experiments, and indirectly by means of novel gravitational effects, such as bore hole g anomalies, predictable black hole masses, flat spiral-galaxy rotation curves, and the expansion of the universe, all without dark matter and dark energy. The dynamics for this 3-space follows from a unique generalisation of Newtonian gravity, once that is cast into a velocity formalism. This new theory of gravity is applied to the solar model of the sun to compute new density, pressure and temperature profiles, using polytrope modelling of the equation of state for the matter. These results should be applied to a re-analysis of solar neutrino production, and to stellar evolution in general.

  3. Dynamical 3-Space Gravity Theory: Effects on Polytropic Solar Models

    Directory of Open Access Journals (Sweden)

    Cahill R. T.

    2011-01-01

    Full Text Available Numerous experiments and observations have confirmed the existence of a dynamical 3-space, detectable directly by light-speed anisotropy experiments, and indirectly by means of novel gravitational effects, such as bore hole g-anomalies, predictable black hole masses, flat spiral-galaxy rotation curves, and the expansion of the universe, all without dark matter and dark energy. The dynamics for this 3-space follows from a unique generalisation of Newtonian gravity, once that is cast into a velocity formalism. This new theory of gravity is applied to the solar model of the sun to compute new density, pressure and temperature profiles, using polytrope modelling of the equation of state for the matter. These results should be applied to a re-analysis of solar neutrino production, and to stellar evolution in general.

  4. Joint Dynamics Modeling and Parameter Identification for Space Robot Applications

    Directory of Open Access Journals (Sweden)

    Adenilson R. da Silva

    2007-01-01

    Full Text Available Long-term mission identification and model validation for in-flight manipulator control system in almost zero gravity with hostile space environment are extremely important for robotic applications. In this paper, a robot joint mathematical model is developed where several nonlinearities have been taken into account. In order to identify all the required system parameters, an integrated identification strategy is derived. This strategy makes use of a robust version of least-squares procedure (LS for getting the initial conditions and a general nonlinear optimization method (MCS—multilevel coordinate search—algorithm to estimate the nonlinear parameters. The approach is applied to the intelligent robot joint (IRJ experiment that was developed at DLR for utilization opportunity on the International Space Station (ISS. The results using real and simulated measurements have shown that the developed algorithm and strategy have remarkable features in identifying all the parameters with good accuracy.

  5. SPACE PARTITIONING FOR PRIVACY ENABLED 3D CITY MODELS

    Directory of Open Access Journals (Sweden)

    Y. Filippovska

    2016-10-01

    For the purpose of privacy enabled visualizations of 3D city models, we propose to partition the (living spaces into privacy regions, each featuring its own level of anonymity. Within each region, the depicted 2D and 3D geometry and imagery is anonymized with cartographic generalization techniques. The underlying spatial partitioning is realized as a 2D map generated as a straight skeleton of the open space between buildings. The resulting privacy cells are then merged according to the privacy requirements associated with each building to form larger regions, their borderlines smoothed, and transition zones established between privacy regions to have a harmonious visual appearance. It is exemplarily demonstrated how the proposed method generates privacy enabled 3D city models.

  6. Computational Model of Primary Visual Cortex Combining Visual Attention for Action Recognition.

    Directory of Open Access Journals (Sweden)

    Na Shu

    Full Text Available Humans can easily understand other people's actions through visual systems, while computers cannot. Therefore, a new bio-inspired computational model is proposed in this paper aiming for automatic action recognition. The model focuses on dynamic properties of neurons and neural networks in the primary visual cortex (V1, and simulates the procedure of information processing in V1, which consists of visual perception, visual attention and representation of human action. In our model, a family of the three-dimensional spatial-temporal correlative Gabor filters is used to model the dynamic properties of the classical receptive field of V1 simple cell tuned to different speeds and orientations in time for detection of spatiotemporal information from video sequences. Based on the inhibitory effect of stimuli outside the classical receptive field caused by lateral connections of spiking neuron networks in V1, we propose surround suppressive operator to further process spatiotemporal information. Visual attention model based on perceptual grouping is integrated into our model to filter and group different regions. Moreover, in order to represent the human action, we consider the characteristic of the neural code: mean motion map based on analysis of spike trains generated by spiking neurons. The experimental evaluation on some publicly available action datasets and comparison with the state-of-the-art approaches demonstrate the superior performance of the proposed model.

  7. Transformation of Neural State Space Models into LFT Models for Robust Control Design

    DEFF Research Database (Denmark)

    Bendtsen, Jan Dimon; Trangbæk, Klaus

    2000-01-01

    This paper considers the extraction of linear state space models and uncertainty models from neural networks trained as state estimators with direct application to robust control. A new method for writing a neural state space model in a linear fractional transformation form in a non-conservative ......-conservative way is proposed, and it is demonstrated how a standard robust control law can be designed for a system described by means of a multi layer perceptron....

  8. A conceptual model for translating omic data into clinical action.

    Science.gov (United States)

    Herr, Timothy M; Bielinski, Suzette J; Bottinger, Erwin; Brautbar, Ariel; Brilliant, Murray; Chute, Christopher G; Denny, Joshua; Freimuth, Robert R; Hartzler, Andrea; Kannry, Joseph; Kohane, Isaac S; Kullo, Iftikhar J; Lin, Simon; Pathak, Jyotishman; Peissig, Peggy; Pulley, Jill; Ralston, James; Rasmussen, Luke; Roden, Dan; Tromp, Gerard; Williams, Marc S; Starren, Justin

    2015-01-01

    Genomic, proteomic, epigenomic, and other "omic" data have the potential to enable precision medicine, also commonly referred to as personalized medicine. The volume and complexity of omic data are rapidly overwhelming human cognitive capacity, requiring innovative approaches to translate such data into patient care. Here, we outline a conceptual model for the application of omic data in the clinical context, called "the omic funnel." This model parallels the classic "Data, Information, Knowledge, Wisdom pyramid" and adds context for how to move between each successive layer. Its goal is to allow informaticians, researchers, and clinicians to approach the problem of translating omic data from bench to bedside, by using discrete steps with clearly defined needs. Such an approach can facilitate the development of modular and interoperable software that can bring precision medicine into widespread practice.

  9. The Use of Evolution in a Central Action Selection Model

    Directory of Open Access Journals (Sweden)

    F. Montes-Gonzalez

    2007-01-01

    Full Text Available The use of effective central selection provides flexibility in design by offering modularity and extensibility. In earlier papers we have focused on the development of a simple centralized selection mechanism. Our current goal is to integrate evolutionary methods in the design of non-sequential behaviours and the tuning of specific parameters of the selection model. The foraging behaviour of an animal robot (animat has been modelled in order to integrate the sensory information from the robot to perform selection that is nearly optimized by the use of genetic algorithms. In this paper we present how selection through optimization finally arranges the pattern of presented behaviours for the foraging task. Hence, the execution of specific parts in a behavioural pattern may be ruled out by the tuning of these parameters. Furthermore, the intensive use of colour segmentation from a colour camera for locating a cylinder sets a burden on the calculations carried out by the genetic algorithm.

  10. A conceptual model for translating omic data into clinical action

    Directory of Open Access Journals (Sweden)

    Timothy M Herr

    2015-01-01

    Full Text Available Genomic, proteomic, epigenomic, and other "omic" data have the potential to enable precision medicine, also commonly referred to as personalized medicine. The volume and complexity of omic data are rapidly overwhelming human cognitive capacity, requiring innovative approaches to translate such data into patient care. Here, we outline a conceptual model for the application of omic data in the clinical context, called "the omic funnel." This model parallels the classic "Data, Information, Knowledge, Wisdom pyramid" and adds context for how to move between each successive layer. Its goal is to allow informaticians, researchers, and clinicians to approach the problem of translating omic data from bench to bedside, by using discrete steps with clearly defined needs. Such an approach can facilitate the development of modular and interoperable software that can bring precision medicine into widespread practice.

  11. Modeling Ships and Space Craft The Science and Art of Mastering the Oceans and Sky

    CERN Document Server

    Hagler, Gina

    2013-01-01

    Modeling Ships and Space Craft: The Science and Art of Mastering the Oceans and Sky begins with the theories of Aristotle and Archimedes, moving on to examine the work of Froude and Taylor, the early aviators and the Wright Brothers, Goddard and the other rocket men, and the computational fluid dynamic models of our time. It examines the ways each used fluid dynamic principles in the design of their vessels. In the process, this book covers the history of hydrodynamic (aero and fluid) theory and its progression – with some very accessible science examples – including seminal theories. Hydrodynamic principles in action are also explored with examples from nature and the works of man. This is a book for anyone interested in the history of technology – specifically the methods and science behind the use of scale models and hydrodynamic principles in the marine and aeronautical designs of today.

  12. Model for the epigenetic mechanism of action of nongenotoxic carcinogens.

    Science.gov (United States)

    Costa, M

    1995-03-01

    On the basis of studies with carcinogenic nickel compounds, we propose a new model of how epigenetic carcinogens might act. This model is based on the fact that nickel compounds induce an increase in chromatin condensation, causing neighboring genes that are actively expressed in euchromatin to be condensed into heterochromatin. Such redistribution in condensation of chromatin would probably only be transient were it not for the DNA cytosine methyl transferase enzyme, which through de novo methylation can cause genes to be inherited in an active state. Actively expressed genes have less cytosine methylation in their promoter whereas hypermethylation of cytosine in promoters is characteristic of inactive genes. Therefore, nickel, through induction of an enhanced condensation state of chromatin that results in the incorporation of critical genes such as the senescence and tumor suppressor genes into heterochromatin (ie, thread on a spool) and the subsequent methylation of this DNA, silences the genetic activity that might be essential for maintenance of a normal cell. This model is consistent with the literature on cytosine methylation and is also consistent with studies of nickel carcinogenesis showing that it increases cytosine methylation. It is also consistent with nickel carcinogenesis being synergistic with many other mutagenic carcinogens (ie, x rays, benzopyrene, or ultraviolet light), which has always suggested that it has a unique component that is not part of the mechanism of these mutagenic carcinogens.

  13. Robust speech recognition based on joint model and feature space optimization of hidden Markov models.

    Science.gov (United States)

    Moon, S; Hwang, J N

    1997-01-01

    The hidden Markov model (HMM) inversion algorithm, based on either the gradient search or the Baum-Welch reestimation of input speech features, is proposed and applied to the robust speech recognition tasks under general types of mismatch conditions. This algorithm stems from the gradient-based inversion algorithm of an artificial neural network (ANN) by viewing an HMM as a special type of ANN. Given input speech features s, the forward training of an HMM finds the model parameters lambda subject to an optimization criterion. On the other hand, the inversion of an HMM finds speech features, s, subject to an optimization criterion with given model parameters lambda. The gradient-based HMM inversion and the Baum-Welch HMM inversion algorithms can be successfully integrated with the model space optimization techniques, such as the robust MINIMAX technique, to compensate the mismatch in the joint model and feature space. The joint space mismatch compensation technique achieves better performance than the single space, i.e. either the model space or the feature space alone, mismatch compensation techniques. It is also demonstrated that approximately 10-dB signal-to-noise ratio (SNR) gain is obtained in the low SNR environments when the joint model and feature space mismatch compensation technique is used.

  14. BPHZ renormalization in configuration space for the A4-model

    Directory of Open Access Journals (Sweden)

    Steffen Pottel

    2018-02-01

    Full Text Available Recent developments for BPHZ renormalization performed in configuration space are reviewed and applied to the model of a scalar quantum field with quartic self-interaction. An extension of the results regarding the short-distance expansion and the Zimmermann identity is shown for a normal product, which is quadratic in the field operator. The realization of the equation of motion is computed for the interacting field and the relation to parametric differential equations is indicated.

  15. Mathematical analysis techniques for modeling the space network activities

    Science.gov (United States)

    Foster, Lisa M.

    1992-01-01

    The objective of the present work was to explore and identify mathematical analysis techniques, and in particular, the use of linear programming. This topic was then applied to the Tracking and Data Relay Satellite System (TDRSS) in order to understand the space network better. Finally, a small scale version of the system was modeled, variables were identified, data was gathered, and comparisons were made between actual and theoretical data.

  16. Multivariable parametric cost model for space and ground telescopes

    Science.gov (United States)

    Stahl, H. Philip; Henrichs, Todd

    2016-09-01

    Parametric cost models can be used by designers and project managers to perform relative cost comparisons between major architectural cost drivers and allow high-level design trades; enable cost-benefit analysis for technology development investment; and, provide a basis for estimating total project cost between related concepts. This paper hypothesizes a single model, based on published models and engineering intuition, for both ground and space telescopes: OTA Cost (X) D (1.75 +/- 0.05) λ (-0.5 +/- 0.25) T-0.25 e (-0.04) Y Specific findings include: space telescopes cost 50X to 100X more ground telescopes; diameter is the most important CER; cost is reduced by approximately 50% every 20 years (presumably because of technology advance and process improvements); and, for space telescopes, cost associated with wavelength performance is balanced by cost associated with operating temperature. Finally, duplication only reduces cost for the manufacture of identical systems (i.e. multiple aperture sparse arrays or interferometers). And, while duplication does reduce the cost of manufacturing the mirrors of segmented primary mirror, this cost savings does not appear to manifest itself in the final primary mirror assembly (presumably because the structure for a segmented mirror is more complicated than for a monolithic mirror).

  17. Scaling exponents in space plasmas: a fractional Levy model

    Science.gov (United States)

    Watkins, N. W.; Credgington, D.; Hnat, B.; Chapman, S. C.; Freeman, M. P.; Greenhough, J.

    Mandelbrot introduced the concept of fractals to describe the non-Euclidean shape of many aspects of the natural world In the time series context he proposed the use of fractional Brownian motion fBm to model non-negligible temporal persistence the Joseph Effect and Levy flights to quantify large discontinuities the Noah Effect In space physics the effects are manifested as intermittency and long-range correlation well-established features of geomagnetic indices and their solar wind drivers In order to capture and quantify the Noah and Joseph effects in one compact model we propose the application of a bridge -fractional Levy motion fLm -to space physics We perform an initial evaluation of some previous scaling results in this paradigm and show how fLm can model the previously observed exponents physics 0509058 in press Space Science Reviews We discuss the similarities and differences between fLm and ambivalent processes based on fractional kinetic equations e g Brockmann et al Nature 2006 and suggest some new directions for the future

  18. Risk Communication Emergency Response Preparedness: Contextual Assessment of the Protective Action Decision Model.

    Science.gov (United States)

    Heath, Robert L; Lee, Jaesub; Palenchar, Michael J; Lemon, Laura L

    2017-06-14

    Studies are continuously performed to improve risk communication campaign designs to better prepare residents to act in the safest manner during an emergency. To that end, this article investigates the predictive ability of the protective action decision model (PADM), which links environmental and social cues, predecision processes (attention, exposure, and comprehension), and risk decision perceptions (threat, alternative protective actions, and stakeholder norms) with protective action decision making. This current quasi-longitudinal study of residents (N = 400 for each year) in a high-risk (chemical release) petrochemical manufacturing community investigated whether PADM core risk perceptions predict protective action decision making. Telephone survey data collected at four intervals (1995, 1998, 2002, 2012) reveal that perceptions of protective actions and stakeholder norms, but not of threat, currently predict protective action decision making (intention to shelter in place). Of significance, rather than threat perceptions, perception of Wally Wise Guy (a spokes-character who advocates shelter in place) correlates with perceptions of protective action, stakeholder norms, and protective action decision making. Wally's response-efficacy advice predicts residents' behavioral intentions to shelter in place, thereby offering contextually sensitive support and refinement for PADM. © 2017 Society for Risk Analysis.

  19. State-space Coil Modelling in Plasma Magnetic Confinement Devices

    Directory of Open Access Journals (Sweden)

    Garrido Aitor J.

    2017-01-01

    Full Text Available The need of robust and optimal control schemes is a key factor for the development of future fusion reactors. This paper has dealt with the state-space modelling of the Ultra-Low Iota Super Elongated Stellarator of the UPV/EHU, using a physical lumped parameter equivalent circuit approach. The model obtained has been validated by means of experimental output data showing an excellent matching with the real system. Besides, it has been designed a MPC scheme that has been successfully implemented both in simulation and experimentally using a real-time control platform.

  20. Efficient parameterization of cardiac action potential models using a genetic algorithm

    Science.gov (United States)

    Cairns, Darby I.; Fenton, Flavio H.; Cherry, E. M.

    2017-09-01

    Finding appropriate values for parameters in mathematical models of cardiac cells is a challenging task. Here, we show that it is possible to obtain good parameterizations in as little as 30-40 s when as many as 27 parameters are fit simultaneously using a genetic algorithm and two flexible phenomenological models of cardiac action potentials. We demonstrate how our implementation works by considering cases of "model recovery" in which we attempt to find parameter values that match model-derived action potential data from several cycle lengths. We assess performance by evaluating the parameter values obtained, action potentials at fit and non-fit cycle lengths, and bifurcation plots for fidelity to the truth as well as consistency across different runs of the algorithm. We also fit the models to action potentials recorded experimentally using microelectrodes and analyze performance. We find that our implementation can efficiently obtain model parameterizations that are in good agreement with the dynamics exhibited by the underlying systems that are included in the fitting process. However, the parameter values obtained in good parameterizations can exhibit a significant amount of variability, raising issues of parameter identifiability and sensitivity. Along similar lines, we also find that the two models differ in terms of the ease of obtaining parameterizations that reproduce model dynamics accurately, most likely reflecting different levels of parameter identifiability for the two models.

  1. A normalized statistical metric space for hidden Markov models.

    Science.gov (United States)

    Lu, Chen; Schwier, Jason M; Craven, Ryan M; Yu, Lu; Brooks, Richard R; Griffin, Christopher

    2013-06-01

    In this paper, we present a normalized statistical metric space for hidden Markov models (HMMs). HMMs are widely used to model real-world systems. Like graph matching, some previous approaches compare HMMs by evaluating the correspondence, or goodness of match, between every pair of states, concentrating on the structure of the models instead of the statistics of the process being observed. To remedy this, we present a new metric space that compares the statistics of HMMs within a given level of statistical significance. Compared with the Kullback-Leibler divergence, which is another widely used approach for measuring model similarity, our approach is a true metric, can always return an appropriate distance value, and provides a confidence measure on the metric value. Experimental results are given for a sample application, which quantify the similarity of HMMs of network traffic in the Tor anonymization system. This application is interesting since it considers models extracted from a system that is intentionally trying to obfuscate its internal workings. In the conclusion, we discuss applications in less-challenging domains, such as data mining.

  2. d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology

    OpenAIRE

    Danilo De Gregorio; Stefano Comai; Luca Posa; Gabriella Gobbi

    2016-01-01

    d-Lysergic Acid Diethylamide (LSD) is known for its hallucinogenic properties and psychotic-like symptoms, especially at high doses. It is indeed used as a pharmacological model of psychosis in preclinical research. The goal of this review was to understand the mechanism of action of psychotic-like effects of LSD. We searched Pubmed, Web of Science, Scopus, Google Scholar and articles’ reference lists for preclinical studies regarding the mechanism of action involved in the psychotic-like eff...

  3. The modeling and solution of course of action generation based on IN-DEA

    Science.gov (United States)

    Wan, Lujun; Li, Wen; Dai, Jiangbin; Huang, Aqian

    2017-08-01

    The course of action (COA) generation is the course of designing the task planning flow, which is one of the key supporting techniques while the military organization executing aerial operation. Due to the outstanding advantage of influence nets (IN), describing the causal logic between random variable, this proposal will introduce IN into the fast building mechanism of COA model. The COA generation model utilize influence nets is established. The probability propagation method is designed, which is based on influence intensity. An improved differential evolution algorithm (IDEA) is designed to solve the action policy optimized selected model. At last, the simulated result of aerial arrack campaign case show the action policy optimized selected in variety influence constants can improve the capability of cause-effect modeling, and the improved differential evolution algorithm has fine convergent and optimized capability.

  4. Space Generic Open Avionics Architecture (SGOAA) reference model technical guide

    Science.gov (United States)

    Wray, Richard B.; Stovall, John R.

    1993-01-01

    This report presents a full description of the Space Generic Open Avionics Architecture (SGOAA). The SGOAA consists of a generic system architecture for the entities in spacecraft avionics, a generic processing architecture, and a six class model of interfaces in a hardware/software system. The purpose of the SGOAA is to provide an umbrella set of requirements for applying the generic architecture interface model to the design of specific avionics hardware/software systems. The SGOAA defines a generic set of system interface points to facilitate identification of critical interfaces and establishes the requirements for applying appropriate low level detailed implementation standards to those interface points. The generic core avionics system and processing architecture models provided herein are robustly tailorable to specific system applications and provide a platform upon which the interface model is to be applied.

  5. A neurocognitive model for understanding treatment action in depression.

    Science.gov (United States)

    Warren, Matthew B; Pringle, Abbie; Harmer, Catherine J

    2015-09-19

    The way in which emotion is represented and processed in the human brain is an expanding area of research and has key implications for how we understand and potentially treat affective disorders such as depression. Characterizing the effects of pharmacological manipulations of key neurotransmitter systems can also help reveal the neurochemical underpinnings of emotional processing and how common antidepressant drugs may work in the treatment of depression and anxiety. This approach has revealed that depression is associated with both neural and behavioural biases towards negative over positive stimuli. Evidence from pharmacological challenge studies suggests that antidepressant treatment acts to normalize these biases early on in treatment, resulting in patients experiencing the world in a more positive way, improving their mood over time. This model is supported by evidence from both pharmacological and non-pharmacological interventions. The unique perspective on antidepressant treatment offered by this approach provides some insights into individual response to treatment, as well as novel approaches to drug development. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  6. Operationalizing the Concept of Value--An Action Research-Based Model

    Science.gov (United States)

    Naslund, Dag; Olsson, Annika; Karlsson, Sture

    2006-01-01

    Purpose: While the importance of measuring customer satisfaction levels is well established, less research exists on how organizations operationalize such knowledge. The purpose of this paper is to describe an action research (AR) case study resulting in a workshop model to operationalize the concept of value. The model facilitates organizational…

  7. MOAtox: A Comprehensive Mode of Action and Acute Aquatic Toxicity Database for Predictive Model Development

    Science.gov (United States)

    tThe mode of toxic action (MOA) has been recognized as a key determinant of chemical toxicity andas an alternative to chemical class-based predictive toxicity modeling. However, the development ofquantitative structure activity relationship (QSAR) and other models has been limite...

  8. A dynamic texture based approach to recognition of facial actions and their temporal models

    NARCIS (Netherlands)

    Koelstra, Sander; Pantic, Maja; Patras, Ioannis (Yannis)

    2010-01-01

    In this work, we propose a dynamic texture-based approach to the recognition of facial Action Units (AUs, atomic facial gestures) and their temporal models (i.e., sequences of temporal segments: neutral, onset, apex, and offset) in near-frontal-view face videos. Two approaches to modeling the

  9. Multi-Conditional Latent Variable Model for Joint Facial Action Unit Detection

    NARCIS (Netherlands)

    Eleftheriadis, Stefanos; Rudovic, Ognjen; Pantic, Maja

    2015-01-01

    We propose a novel multi-conditional latent variable model for simultaneous facial feature fusion and detection of facial action units. In our approach we exploit the structure-discovery capabilities of generative models such as Gaussian processes, and the discriminative power of classifiers such as

  10. Nurses' intention to leave: critically analyse the theory of reasoned action and organizational commitment model.

    Science.gov (United States)

    Liou, Shwu-Ru

    2009-01-01

    To systematically analyse the Organizational Commitment model and Theory of Reasoned Action and determine concepts that can better explain nurses' intention to leave their job. The Organizational Commitment model and Theory of Reasoned Action have been proposed and applied to understand intention to leave and turnover behaviour, which are major contributors to nursing shortage. However, the appropriateness of applying these two models in nursing was not analysed. Three main criteria of a useful model were used for the analysis: consistency in the use of concepts, testability and predictability. Both theories use concepts consistently. Concepts in the Theory of Reasoned Action are defined broadly whereas they are operationally defined in the Organizational Commitment model. Predictability of the Theory of Reasoned Action is questionable whereas the Organizational Commitment model can be applied to predict intention to leave. A model was proposed based on this analysis. Organizational commitment, intention to leave, work experiences, job characteristics and personal characteristics can be concepts for predicting nurses' intention to leave. Nursing managers may consider nurses' personal characteristics and experiences to increase their organizational commitment and enhance their intention to stay. Empirical studies are needed to test and cross-validate the re-synthesized model for nurses' intention to leave their job.

  11. THE MODEL CHARACTERISTICS OF JUMP ACTIONS STRUCTURE OF HIGH PERFORMANCE FEMALE VOLLEYBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Stech M.

    2012-12-01

    Full Text Available The purpose of this study was to develop generalized and individual models of the jump actions of skilled female volleyball players. The main prerequisite for the development of the jump actions models were the results of our earlier studies of factor structure of jump actions of 10 sportswomen of the Polish volleyball team "Gedania" (Premier League in the preparatory and competitive periods of the annual cycle of preparation. The athletes age was 22.0 +- 2.9 years, the sports experience - 8.1 +- 3.1 years, body height - 181.9 +- 8.4 years and body weight - 72.8 +- 10.8 kg. Mathematical and statistical processing of the data (the definition of M ± SD and significant differences between the samples was performed using a standard computer program "STATISTICA 7,0". Based on the analysis of the factor structure of 20 jump actions of skilled women volleyball players determined to within 5 of the most informative indexes and their tentative values recommended for the formation of a generalized model of this structure. Comparison of individual models of jump actions of skilled women volleyball players with their generalized models in different periods of preparation can be used for the rational choice of means and methods for the increasing of the training process efficiency.

  12. On vector autoregressive modeling in space and time

    Science.gov (United States)

    di Giacinto, Valter

    2010-06-01

    Despite the fact that it provides a potentially useful analytical tool, allowing for the joint modeling of dynamic interdependencies within a group of connected areas, until lately the VAR approach had received little attention in regional science and spatial economic analysis. This paper aims to contribute in this field by dealing with the issues of parameter identification and estimation and of structural impulse response analysis. In particular, there is a discussion of the adaptation of the recursive identification scheme (which represents one of the more common approaches in the time series VAR literature) to a space-time environment. Parameter estimation is subsequently based on the Full Information Maximum Likelihood (FIML) method, a standard approach in structural VAR analysis. As a convenient tool to summarize the information conveyed by regional dynamic multipliers with a specific emphasis on the scope of spatial spillover effects, a synthetic space-time impulse response function (STIR) is introduced, portraying average effects as a function of displacement in time and space. Asymptotic confidence bands for the STIR estimates are also derived from bootstrap estimates of the standard errors. Finally, to provide a basic illustration of the methodology, the paper presents an application of a simple bivariate fiscal model fitted to data for Italian NUTS 2 regions.

  13. The MASTER-99 space debris and meteoroid environment model

    Science.gov (United States)

    Klinkrad, H.; Bendisch, J.; Bunte, K. D.; Krag, H.; Sdunnus, H.; Wegener, P.

    2001-01-01

    MASTER-99 is a space debris and meteoroid environment model produced by TU Braunschweig (D), eta_max space (D), and DERA (UK) under an ESA contract. The model allows to compute particulate impact fluxes on any terrestrial target orbit up to geostationary altitudes. Flux contributions can be discriminated with respect to debris source types (catalog objects, explosion and collision fragments, NaK droplets, solid rocket motor dust and slag, impact ejecta, and surface degradation products), meteoroid source types (Divine-Staubach populations, and annual stream events), and with respect to origin and impact direction of each flux contributing particulate. Impact fluxes of meteoroids and debris down to 1 μm sizes can be determined for spherical targets, for tumbling plates, or for oriented, planar surfaces which are controlled according to standard attitude steering laws. MASTER-99 is distributed by ESA/ESOC on a CD ROM which includes user documentation, and the necessary data files, executables, and GUI driven installation scripts for the most common operating systems and computer platforms. MASTER-99 is delivered together with PROOF-99, a program for radar and optical observation forecasting. Based on the MASTER-99 population larger than 1 mm, it predicts debris detections from ground-based or space-based sensors (radars or telescopes) of user-defined system performances.

  14. Structural analysis based on state-space modeling.

    Science.gov (United States)

    Stultz, C M; White, J V; Smith, T F

    1993-03-01

    A new method has been developed to compute the probability that each amino acid in a protein sequence is in a particular secondary structural element. Each of these probabilities is computed using the entire sequence and a set of predefined structural class models. This set of structural classes is patterned after Jane Richardson's taxonomy for the domains of globular proteins. For each structural class considered, a mathematical model is constructed to represent constraints on the pattern of secondary structural elements characteristic of that class. These are stochastic models having discrete state spaces (referred to as hidden Markov models by researchers in signal processing and automatic speech recognition). Each model is a mathematical generator of amino acid sequences; the sequence under consideration is modeled as having been generated by one model in the set of candidates. The probability that each model generated the given sequence is computed using a filtering algorithm. The protein is then classified as belonging to the structural class having the most probable model. The secondary structure of the sequence is then analyzed using a "smoothing" algorithm that is optimal for that structural class model. For each residue position in the sequence, the smoother computes the probability that the residue is contained within each of the defined secondary structural elements of the model. This method has two important advantages: (1) the probability of each residue being in each of the modeled secondary structural elements is computed using the totality of the amino acid sequence, and (2) these probabilities are consistent with prior knowledge of realizable domain folds as encoded in each model. As an example of the method's utility, we present its application to flavodoxin, a prototypical alpha/beta protein having a central beta-sheet, and to thioredoxin, which belongs to a similar structural class but shares no significant sequence similarity.

  15. Theories and models on the biological of cells in space

    Science.gov (United States)

    Todd, P.; Klaus, D. M.

    1996-01-01

    A wide variety of observations on cells in space, admittedly made under constraining and unnatural conditions in may cases, have led to experimental results that were surprising or unexpected. Reproducibility, freedom from artifacts, and plausibility must be considered in all cases, even when results are not surprising. The papers in symposium on 'Theories and Models on the Biology of Cells in Space' are dedicated to the subject of the plausibility of cellular responses to gravity -- inertial accelerations between 0 and 9.8 m/sq s and higher. The mechanical phenomena inside the cell, the gravitactic locomotion of single eukaryotic and prokaryotic cells, and the effects of inertial unloading on cellular physiology are addressed in theoretical and experimental studies.

  16. Nonlinear State Space Modeling and System Identification for Electrohydraulic Control

    Directory of Open Access Journals (Sweden)

    Jun Yan

    2013-01-01

    Full Text Available The paper deals with nonlinear modeling and identification of an electrohydraulic control system for improving its tracking performance. We build the nonlinear state space model for analyzing the highly nonlinear system and then develop a Hammerstein-Wiener (H-W model which consists of a static input nonlinear block with two-segment polynomial nonlinearities, a linear time-invariant dynamic block, and a static output nonlinear block with single polynomial nonlinearity to describe it. We simplify the H-W model into a linear-in-parameters structure by using the key term separation principle and then use a modified recursive least square method with iterative estimation of internal variables to identify all the unknown parameters simultaneously. It is found that the proposed H-W model approximates the actual system better than the independent Hammerstein, Wiener, and ARX models. The prediction error of the H-W model is about 13%, 54%, and 58% less than the Hammerstein, Wiener, and ARX models, respectively.

  17. The Production and the Uneven Valorization of Urban Space in Campos Dos Goytacazes-RJ: An Analysis of State and Real Estate Developers Actions

    Directory of Open Access Journals (Sweden)

    Marcos Antônio Silvestre Gomes

    2015-07-01

    Full Text Available This article discusses some aspects of the production of urban space considering the social agents actions. The methodology was based on literature searches, data surveys and interviews in public and private agencies, empirical observations and mapping of the urban area. The methodology was based on literature searches, data surveys and interviews in public and private agencies, empirical observations and mapping of the urban area. The objective is to present an analysis of state and real estate developers actions in the production and uneven valorization of urban space in Campos dos Goytacazes-RJ. The results of work indicate the intensification and complexification of actions of these agents with the advent of the oil economy. In the period 1981-2011 there was an intense valuation of South West-East axis of the city, with a vertiginous process of vertical integration and deployment of a high standard closed allotments, which has

  18. Liénard-type models for the simulation of the action potential of cardiac nodal cells

    Science.gov (United States)

    Podziemski, P.; Żebrowski, J. J.

    2013-10-01

    Existing models of cardiac cells which include multi-variable cardiac transmembrane current are too complex to simulate the long time dynamical properties of the heart rhythm. The large number of parameters that need to be defined and set for such models make them not only cumbersome to use but also require a large computing power. Consequently, the application of such models for the bedside analysis of heart rate of a specific patient may be difficult. Other ways of modelling need to be investigated. We consider the general problem of developing a model of cardiac pacemaker tissue that allows to combine the investigation of phenomena at a time scale of thousands of heart beats with the ability to reproduce realistic tissue-level characteristics of cell dynamics. We propose a modified van der Pol-Duffing equation-a Liénard-type oscillator-as a phenomenological model for cardiac nodal tissue, with certain important physiological similarities to ion-channel models of cardiac pacemaker cells. The model presented here is specifically designed to qualitatively reproduce mesoscopic characteristics of cell dynamics, including action potential duration (APD) restitution properties, phase response characteristics, and phase space structure. We show that these characteristics agree qualitatively with the extensive ionic models and experimental results in the literature [Anumonwo et al., 1991, [33], Cao et al., 1999, [49], Coster and Celler, 2003, [31], Qu, 2004, [45], Tsalikakis et al., 2007, [32], Inada et al., 2009, [14], Qu et al., 2010, [50

  19. Le marketing urbain comme dispositif de légitimation Urban marketing as a tool of legitimation. Elite actions and civic spaces

    Directory of Open Access Journals (Sweden)

    Damien Vanneste

    2007-11-01

    Full Text Available À une époque où s’entrecroisent l’idée forte de changement permanent et la valorisation d’espaces démocratiques, il semble opportun de repenser la participation à la production de l’espace local et les modes d’action des élites. À partir d’une étude de cas qui retrace les cheminements de différents projets locaux en Belgique, un système d’action politique cohérent qui mêle visibilisation de l’action, activisme et production d’un consensus est dégagé. Ce dispositif de légitimation peut alors être étudié en termes de marketing urbain et permettre de confronter les contours organisationnels actuels de la politique à l’horizon démocratique.At a time where the strong notion of permanent change and the valorization of democratic spaces intertwine, it seems appropriate to rethink the participation in the production of local space and the modes of elite action. A case study tracing the evolution of different local projects highlights a coherent system of political action, coalescing action visibility, activism and consensus reaching. This tool of legitimation will be conceived of in terms of urban marketing. This analysis will ultimately allow to examine against a democratic backdrop current organizational outlines of politics.

  20. Requirements for high level models supporting design space exploration in model-based systems engineering

    NARCIS (Netherlands)

    Haveman, Steven; Bonnema, Gerrit Maarten

    2013-01-01

    Most formal models are used in detailed design and focus on a single domain. Few effective approaches exist that can effectively tie these lower level models to a high level system model during design space exploration. This complicates the validation of high level system requirements during

  1. Unsupervised learning of reflexive and action-based affordances to model adaptive navigational behavior

    Directory of Open Access Journals (Sweden)

    Daniel Weiller

    2010-05-01

    Full Text Available Here we introduce a cognitive model capable to model a variety of behavioral domains and apply it to a navigational task. We used place cells as sensory representation, such that the cells’ place fields divided the environment into discrete states. The robot learns knowledge of the environment by memorizing the sensory outcome of its motor actions. This is composed of a central process, learning the probability of state-to-state transitions by motor actions and a distal processing routine, learning the extent to which these state-to-state transitions are caused by sensory-driven reflex behavior (obstacle avoidance. Navigational decision making integrates central and distal learned environmental knowledge to select an action that leads to a goal state. Differentiating distal and central processing increases the behavioral accuracy of the selected actions and the ability of behavioral adaptation to a changed environment. We propose that the system can canonically be expanded to model other behaviors, using alternative definitions of states and actions. The emphasis of this paper is to test this general cognitive model on a robot in a real world environment

  2. Unsupervised learning of reflexive and action-based affordances to model adaptive navigational behavior.

    Science.gov (United States)

    Weiller, Daniel; Läer, Leonhard; Engel, Andreas K; König, Peter

    2010-01-01

    Here we introduce a cognitive model capable to model a variety of behavioral domains and apply it to a navigational task. We used place cells as sensory representation, such that the cells' place fields divided the environment into discrete states. The robot learns knowledge of the environment by memorizing the sensory outcome of its motor actions. This is composed of a central process, learning the probability of state-to-state transitions by motor actions and a distal processing routine, learning the extent to which these state-to-state transitions are caused by sensory-driven reflex behavior (obstacle avoidance). Navigational decision making integrates central and distal learned environmental knowledge to select an action that leads to a goal state. Differentiating distal and central processing increases the behavioral accuracy of the selected actions and the ability of behavioral adaptation to a changed environment. We propose that the system can canonically be expanded to model other behaviors, using alternative definitions of states and actions. The emphasis of this paper is to test this general cognitive model on a robot in a real-world environment.

  3. XY-model on planar and space curves

    Energy Technology Data Exchange (ETDEWEB)

    Dandoloff, Rossen [Laboratoire de Physique et Modelisation, Universite de Cergy-Pontoise, F-95302 Cergy-Pontoise (France); Saxena, Avadh [Theoretical Division and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)]. E-mail: avadh@lanl.gov

    2006-10-30

    We study the XY-model on a planar curve with a segment with constant curvature {kappa}{sub 0} and a space curve with a segment with both constant curvature {kappa}{sub 0} and torsion {tau}{sub 0}. In the first case the bent segment breaks the rotational invariance of the XY-model and thus we get a fractional static sine-Gordon soliton interpolating between the two states {theta}{sub 1} and {theta}{sub 2}. In the second case the helical segment breaks the helicity of the model and thus creating a ground state and a metastable state spin configuration with a fractional static soliton. For sufficiently large {tau}{sub 0} the static soliton solution can be more stable than the trivial ({theta}=n{pi}/2) solution. The curvature introduces nonlinearity in the problem thereby localizing the energy in the region with nonzero curvature.

  4. Space shuttle’s liftoff: a didactical model

    Science.gov (United States)

    Borghi, Riccardo; Spinozzi, Turi Maria

    2017-07-01

    The pedagogical aim of the present paper, thought for an undergraduate audience, is to help students to appreciate how the development of elementary models based on physics first principles is a fundamental and necessary preliminary step for the behaviour of complex real systems to be grasped with minimal amounts of math. In some particularly fortunate cases, such models also show reasonably good results when are compared to reality. The speed behaviour of the Space Shuttle during its first two minutes of flight from liftoff is here analysed from such a didactical point of view. Only the momentum conservation law is employed to develop the model, which is eventually applied to quantitatively interpret the telemetry of the 2011 last launches of Shuttle Discovery and Shuttle Endeavour. To the STS-51-L and STS-107 astronauts, in memoriam.

  5. Modeling of action potential generation in NG108-15 cells.

    Science.gov (United States)

    Molnar, Peter; Hickman, James J

    2014-01-01

    In order to explore the possibility of identifying toxins based on their effect on the shape of action potentials, we created a computer model of the action potential generation in NG108-15 cells (a neuroblastoma/glioma hybrid cell line). To generate the experimental data for model validation, voltage-dependent sodium, potassium and high-threshold calcium currents, as well as action potentials, were recorded from NG108-15 cells with conventional whole-cell patch-clamp methods. Based on the classic Hodgkin-Huxley formalism and the linear thermodynamic description of the rate constants, ion-channel parameters were estimated using an automatic fitting method. Utilizing the established parameters, action potentials were generated using the Hodgkin-Huxley formalism and were fitted to the recorded action potentials. To demonstrate the applicability of the method for toxin detection and discrimination, the effect of tetrodotoxin (a sodium channel blocker) and tefluthrin (a pyrethroid that is a sodium channel opener) were studied. The two toxins affected the shape of the action potentials differently, and their respective effects were identified based on the predicted changes in the fitted parameters.

  6. Modeling and simulation of the space platform power system

    Science.gov (United States)

    Patil, A. R.; Kim, S. J.; Cho, B. H.; Lee, F. C.

    1990-01-01

    A comprehensive computer-aided modeling and simulation technique for the space platform power system is described. Large-signal and small-signal modeling is presented for the system components. The component models have been integrated to form the complete power system model. The system model is shown to be a powerful tool in simulating the behavior of the system with variation of illumination level and load. It can be used to study the bus regulation in each mode and to observe mode changes as the solar array is subjected to transitions from sunlight to eclipse and back to sunlight. System simulations show how the bus regulation is maintained by activating the shunt switching unit, the charger, or the discharger, depending on the available illumination level. The system model is suitable for verifying hardware results of for analyzing the performance of a proposed system where hardware testing is not feasible. The EASY5 dynamic analysis program is used as the host software for the modeling and simulation.

  7. A Knowledge Discovery from POS Data using State Space Models

    Science.gov (United States)

    Sato, Tadahiko; Higuchi, Tomoyuki

    The number of competing-brands changes by new product's entry. The new product introduction is endemic among consumer packaged goods firm and is an integral component of their marketing strategy. As a new product's entry affects markets, there is a pressing need to develop market response model that can adapt to such changes. In this paper, we develop a dynamic model that capture the underlying evolution of the buying behavior associated with the new product. This extends an application of a dynamic linear model, which is used by a number of time series analyses, by allowing the observed dimension to change at some point in time. Our model copes with a problem that dynamic environments entail: changes in parameter over time and changes in the observed dimension. We formulate the model with framework of a state space model. We realize an estimation of the model using modified Kalman filter/fixed interval smoother. We find that new product's entry (1) decreases brand differentiation for existing brands, as indicated by decreasing difference between cross-price elasticities; (2) decreases commodity power for existing brands, as indicated by decreasing trend; and (3) decreases the effect of discount for existing brands, as indicated by a decrease in the magnitude of own-brand price elasticities. The proposed framework is directly applicable to other fields in which the observed dimension might be change, such as economic, bioinformatics, and so forth.

  8. The 2006 Kennedy Space Center Range Reference Atmosphere Model Validation Study and Sensitivity Analysis to the Performance of the National Aeronautics and Space Administration's Space Shuttle Vehicle

    Science.gov (United States)

    Burns, Lee; Decker, Ryan; Harrington, Brian; Merry, Carl

    2008-01-01

    The Kennedy Space Center (KSC) Range Reference Atmosphere (RRA) is a statistical model that summarizes wind and thermodynamic atmospheric variability from surface to 70 km. The National Aeronautics and Space Administration's (NASA) Space Shuttle program, which launches from KSC, utilizes the KSC RRA data to evaluate environmental constraints on various aspects of the vehicle during ascent. An update to the KSC RRA was recently completed. As part of the update, the Natural Environments Branch at NASA's Marshall Space Flight Center (MSFC) conducted a validation study and a comparison analysis to the existing KSC RRA database version 1983. Assessments to the Space Shuttle vehicle ascent profile characteristics were performed by JSC/Ascent Flight Design Division to determine impacts of the updated model to the vehicle performance. Details on the model updates and the vehicle sensitivity analyses with the update model are presented.

  9. Space Launch System Scale Model Acoustic Test Ignition Overpressure Testing

    Science.gov (United States)

    Nance, Donald K.; Liever, Peter A.

    2015-01-01

    The overpressure phenomenon is a transient fluid dynamic event occurring during rocket propulsion system ignition. This phenomenon results from fluid compression of the accelerating plume gas, subsequent rarefaction, and subsequent propagation from the exhaust trench and duct holes. The high-amplitude unsteady fluid-dynamic perturbations can adversely affect the vehicle and surrounding structure. Commonly known as ignition overpressure (IOP), this is an important design-to environment for the Space Launch System (SLS) that NASA is currently developing. Subscale testing is useful in validating and verifying the IOP environment. This was one of the objectives of the Scale Model Acoustic Test (SMAT), conducted at Marshall Space Flight Center (MSFC). The test data quantifies the effectiveness of the SLS IOP suppression system and improves the analytical models used to predict the SLS IOP environments. The reduction and analysis of the data gathered during the SMAT IOP test series requires identification and characterization of multiple dynamic events and scaling of the event waveforms to provide the most accurate comparisons to determine the effectiveness of the IOP suppression systems. The identification and characterization of the overpressure events, the waveform scaling, the computation of the IOP suppression system knockdown factors, and preliminary comparisons to the analytical models are discussed.

  10. Modeling velocity space-time correlations in wind farms

    Science.gov (United States)

    Lukassen, Laura J.; Stevens, Richard J. A. M.; Meneveau, Charles; Wilczek, Michael

    2016-11-01

    Turbulent fluctuations of wind velocities cause power-output fluctuations in wind farms. The statistics of velocity fluctuations can be described by velocity space-time correlations in the atmospheric boundary layer. In this context, it is important to derive simple physics-based models. The so-called Tennekes-Kraichnan random sweeping hypothesis states that small-scale velocity fluctuations are passively advected by large-scale velocity perturbations in a random fashion. In the present work, this hypothesis is used with an additional mean wind velocity to derive a model for the spatial and temporal decorrelation of velocities in wind farms. It turns out that in the framework of this model, space-time correlations are a convolution of the spatial correlation function with a temporal decorrelation kernel. In this presentation, first results on the comparison to large eddy simulations will be presented and the potential of the approach to characterize power output fluctuations of wind farms will be discussed. Acknowledgements: 'Fellowships for Young Energy Scientists' (YES!) of FOM, the US National Science Foundation Grant IIA 1243482, and support by the Max Planck Society.

  11. State-space modeling and analysis of fault arcs

    Energy Technology Data Exchange (ETDEWEB)

    Mamis, M. Salih [Department of Electrical and Electronics Eng., Engineering Faculty, Inonu University, 44280-Malatya (Turkey); Meral, M. Emin [Van Vocational School of Higher Education, University of Yuzuncu Yil, 65080-Van (Turkey)

    2005-09-15

    This paper presents a state-space technique for the transient analysis of power systems arcing faults, using the time-dependent dynamic resistance model. The state equations describing the system behavior are derived and these equations are solved by the use of numerical integration. Based on the solution technique, a computer program in the MATLAB environment is developed. The computer program is capable of directly formulating the state equations for a transmission line with a fault arc and it produces data for the arc voltage, current and resistance. (author)

  12. Space charge templates for high-current beam modeling

    Energy Technology Data Exchange (ETDEWEB)

    Vorobiev, Leonid G.; /Fermilab

    2008-07-01

    A computational method to evaluate space charge potential and gradients of charged particle beam in the presence of conducting boundaries, has been introduced. The three-dimensional (3D) field of the beam can be derived as a convolution of macro Green's functions (template fields), satisfying the same boundary conditions, as the original beam. Numerical experiments gave a confidence that space charge effects can be modeled by templates with enough accuracy and generality within dramatically faster computational times than standard combination: a grid density + Poisson solvers, realized in the most of Particle in Cell codes. The achieved rapidity may significantly broaden the high-current beam design space, making the optimization in automatic mode possible, which so far was only feasible for simplest self-field formulations such as rms envelope equations. The template technique may be used as a standalone program, or as an optional field solver in existing beam dynamics codes both in one-passage structures and in rings.

  13. a New Model for Describing Evolution and Control of Disaster System Including Instantaneous and Continuous Actions

    Science.gov (United States)

    Chen, Chang-Kun; Li, Zhi; Sun, Yun-Feng

    A new model for describing the disaster system including instantaneous and continuous action synchronously has been developed. The model is composed of three primary parts, that is, the impact from its causative disaster events, stochastic noise of disaster node and self-healing function, and every part is modeled concretely in terms of their characteristics in practice. Some key parameters, namely link appearance probability, retardation coefficient, ultimate repair capacity of government, dynamical modes considering different disaster evolving chains, and the positions of link with the specific performance in disaster network system are involved. Combined with a case study, the proposed model is applied to a certain disaster evolution system, and the influence law of different parameters on disaster evolution process, in disaster networks with instantaneous-action and/or continuous-action, is presented and compared. The results indicate that the destructive impact in the networks by link in continuous action is far greater an order of magnitude than that in instantaneous action. If a link in continuous action emerges in the disaster network system, properties of the causative event for the link, link appearance probability and its position in the network all have a notable influence to the severity of the disaster network. In addition, some peculiar phenomena are also commendably observed in the disaster evolution process based on the model, such as the multipeaks emerging in the destroyed rate number curve for some crisis nodes caused by their various inducing paths together with the relevant retardation coefficients, the existence of the critical value for ultimate repair capacity to recover the disaster node, and so on.

  14. Mind the Gap: Exploring the Underground of the NASA Space Cancer Risk Model

    Science.gov (United States)

    Chappell, L. J.; Elgart, S. R.; Milder, C. M.; Shavers, M. R.; Semones, E. J.; Huff, J. L.

    2017-01-01

    ) defines the knowledge gaps that impact our understanding of the cancer risks. These gaps are outlined in NASA's Human Research Roadmap [4], which identifies the research questions and actions recommended for reducing the uncertainty in the current NSCR model and for formulation of future models. The greatest contributors to uncertainty in the current model include radiation quality, dose rate effects, and the transfer of exposure-based risk from other populations to an astronaut population. Future formulations of the risk model may benefit from including other potential sources of uncertainty such as space dosimetry, errors in human epidemiology data, and the impact of microgravity and other spaceflight stressors. Here, we discuss the current capabilities of the NSCR-2012 model and several immediate research needs, highlighting areas expected to have an operational impact on the current model schema. The following subway-style route map outlines the NSCR-2012 model (Green Line), emphasizing the research gaps in the Human Research Roadmap for risk of radiation-induced carcinogenesis (Stops on Dashed Lines). The map diagrams how these research gaps feed specific portions of the model.

  15. Predicting Individual Action Switching in Passively Experienced and Continuous Interactive Tasks Using the Fluid Events Model

    Directory of Open Access Journals (Sweden)

    Gabriel A. Radvansky

    2016-01-01

    Full Text Available The Fluid Events Model is aimed at predicting changes in the actions people take on a moment-by-moment basis. In contrast with other research on action selection, this work does not investigate why some course of action was selected, but rather the likelihood of discontinuing the current course of action and selecting another in the near future. This is done using both task-based and experience-based factors. Prior work evaluated this model in the context of trial-by-trial, independent, interactive events, such as choosing how to copy a figure of a line drawing. In this paper, we extend this model to more covert event experiences, such as reading narratives, as well as to continuous interactive events, such as playing a video game. To this end, the model was applied to existing data sets of reading time and event segmentation for written and picture stories. It was also applied to existing data sets of performance in a strategy board game, an aerial combat game, and a first person shooter game in which a participant’s current state was dependent on prior events. The results revealed that the model predicted behavior changes well, taking into account both the theoretically defined structure of the described events, as well as a person’s prior experience. Thus, theories of event cognition can benefit from efforts that take into account not only how events in the world are structured, but also how people experience those events.

  16. Health belief model and reasoned action theory in predicting water saving behaviors in yazd, iran.

    Science.gov (United States)

    Morowatisharifabad, Mohammad Ali; Momayyezi, Mahdieh; Ghaneian, Mohammad Taghi

    2012-01-01

    People's behaviors and intentions about healthy behaviors depend on their beliefs, values, and knowledge about the issue. Various models of health education are used in deter¬mining predictors of different healthy behaviors but their efficacy in cultural behaviors, such as water saving behaviors, are not studied. The study was conducted to explain water saving beha¬viors in Yazd, Iran on the basis of Health Belief Model and Reasoned Action Theory. The cross-sectional study used random cluster sampling to recruit 200 heads of households to collect the data. The survey questionnaire was tested for its content validity and reliability. Analysis of data included descriptive statistics, simple correlation, hierarchical multiple regression. Simple correlations between water saving behaviors and Reasoned Action Theory and Health Belief Model constructs were statistically significant. Health Belief Model and Reasoned Action Theory constructs explained 20.80% and 8.40% of the variances in water saving beha-viors, respectively. Perceived barriers were the strongest Predictor. Additionally, there was a sta¬tistically positive correlation between water saving behaviors and intention. In designing interventions aimed at water waste prevention, barriers of water saving behaviors should be addressed first, followed by people's attitude towards water saving. Health Belief Model constructs, with the exception of perceived severity and benefits, is more powerful than is Reasoned Action Theory in predicting water saving behavior and may be used as a framework for educational interventions aimed at improving water saving behaviors.

  17. Health Belief Model and Reasoned Action Theory in Predicting Water Saving Behaviors in Yazd, Iran

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Ghaneian

    2012-12-01

    Full Text Available Background: People's behaviors and intentions about healthy behaviors depend on their beliefs, values, and knowledge about the issue. Various models of health education are used in deter-mining predictors of different healthy behaviors but their efficacy in cultural behaviors, such as water saving behaviors, are not studied. The study was conducted to explain water saving beha-viors in Yazd, Iran on the basis of Health Belief Model and Reasoned Action Theory. Methods: The cross-sectional study used random cluster sampling to recruit 200 heads of households to collect the data. The survey questionnaire was tested for its content validity and reliability. Analysis of data included descriptive statistics, simple correlation, hierarchical multiple regression. Results: Simple correlations between water saving behaviors and Reasoned Action Theory and Health Belief Model constructs were statistically significant. Health Belief Model and Reasoned Action Theory constructs explained 20.80% and 8.40% of the variances in water saving beha-viors, respectively. Perceived barriers were the strongest Predictor. Additionally, there was a sta-tistically positive correlation between water saving behaviors and intention. Conclusion: In designing interventions aimed at water waste prevention, barriers of water saving behaviors should be addressed first, followed by people's attitude towards water saving. Health Belief Model constructs, with the exception of perceived severity and benefits, is more powerful than is Reasoned Action Theory in predicting water saving behavior and may be used as a framework for educational interventions aimed at improving water saving behaviors.

  18. Evidence for the embodiment of space perception: concurrent hand but not arm action moderates reachability and egocentric distance perception.

    Science.gov (United States)

    Grade, Stéphane; Pesenti, Mauro; Edwards, Martin G

    2015-01-01

    The perception of reachability (i.e., whether an object is within reach) relies on body representations and action simulation. Similarly, egocentric distance estimation (i.e., the perception of the distance an object is from the self) is thought to be partly derived from embodied action simulation. Although motor simulation is important for both, it is unclear whether the cognitive processes underlying these behaviors rely on the same motor processes. To investigate this, we measured the impact of a motor interference dual-task paradigm on reachability judgment and egocentric distance estimation, while allocentric length estimation (i.e., how distant two stimuli are from each other independent from the self) was used as a control task. Participants were required to make concurrent actions with either hand actions of foam ball grip squeezing or arm actions of weight lifting, or no concurrent actions. Results showed that concurrent squeeze actions significantly slowed response speed in the reachability judgment and egocentric distance estimation tasks, but that there was no impact of the concurrent actions on allocentric length estimation. Together, these results suggest that reachability and distance perception, both egocentric perspective tasks, and in contrast to the allocentric perspective task, involve action simulation cognitive processes. The results are discussed in terms of the implication of action simulation when evaluating the position of a target relative to the observer's body, supporting an embodied view of spatial cognition.

  19. Evidence for the embodiment of space perception: Concurrent hand but not arm action moderates reachability and egocentric distance perception.

    Directory of Open Access Journals (Sweden)

    Stephane eGrade

    2015-06-01

    Full Text Available The perception of reachability (i.e., whether an object is within reach relies on body representations and action simulation. Similarly, egocentric distance estimation (i.e., the perception of the distance an object is from the self is thought to be partly derived from embodied action simulation. Although motor simulation is important for both, it is unclear whether the cognitive processes underlying these behaviors rely on the same motor processes. To investigate this, we measured the impact of a motor interference dual-task paradigm on reachability judgment, egocentric distance estimation, and allocentric length estimation (i.e., how distant two stimuli are from each other independent from the self used as a control task. Participants were required to make concurrent actions with either hand actions of foam ball grip squeezing or arm actions of weight lifting, or no concurrent actions. Results showed that concurrent squeeze actions significantly slowed response speed in the reachability judgment and egocentric distance estimation tasks, but that there was no impact of the concurrent actions on allocentric length estimation. Together, these results suggest that reachability and distance perception, both egocentric perspective tasks, and in contrast to the allocentric perspective task, involve action simulation cognitive processes. The results are discussed in terms of the implication of action simulation when evaluating the position of a target relative to the observer’s body, supporting an embodied view of spatial cognition.

  20. Finite-action solutions of Yang-Mills equations on de Sitter dS4 and anti-de Sitter AdS4 spaces

    Science.gov (United States)

    Ivanova, Tatiana A.; Lechtenfeld, Olaf; Popov, Alexander D.

    2017-11-01

    We consider pure SU(2) Yang-Mills theory on four-dimensional de Sitter dS4 and anti-de Sitter AdS4 spaces and construct various solutions to the Yang-Mills equations. On de Sitter space we reduce the Yang-Mills equations via an SU(2)-equivariant ansatz to Newtonian mechanics of a particle moving in R^3 under the influence of a quartic potential. Then we describe magnetic and electric-magnetic solutions, both Abelian and non-Abelian, all having finite energy and finite action. A similar reduction on anti-de Sitter space also yields Yang-Mills solutions with finite energy and action. We propose a lower bound for the action on both backgrounds. Employing another metric on AdS4, the SU(2) Yang-Mills equations are reduced to an analytic continuation of the above particle mechanics from R^3 to R^{2,1} . We discuss analytical solutions to these equations, which produce infinite-action configurations. After a Euclidean continuation of dS4 and AdS4 we also present self-dual (instanton-type) Yang-Mills solutions on these backgrounds.

  1. Applications of the International Space Station Probabilistic Risk Assessment Model

    Science.gov (United States)

    Grant, Warren; Lutomski, Michael G.

    2011-01-01

    Recently the International Space Station (ISS) has incorporated more Probabilistic Risk Assessments (PRAs) in the decision making process for significant issues. Future PRAs will have major impact to ISS and future spacecraft development and operations. These PRAs will have their foundation in the current complete ISS PRA model and the current PRA trade studies that are being analyzed as requested by ISS Program stakeholders. ISS PRAs have recently helped in the decision making process for determining reliability requirements for future NASA spacecraft and commercial spacecraft, making crew rescue decisions, as well as making operational requirements for ISS orbital orientation, planning Extravehicular activities (EVAs) and robotic operations. This paper will describe some applications of the ISS PRA model and how they impacted the final decision. This paper will discuss future analysis topics such as life extension, requirements of new commercial vehicles visiting ISS.

  2. State-space based modeling for imaging system identification

    Science.gov (United States)

    Kaur, Balvinder; Hixson, Jonathan G.

    2017-05-01

    State-space (SS) based modeling for imaging electro-optical (EO) systems representing various states facilitates a method for system estimation. Traditionally linear shift-invariant (LSI) systems are modeled using Fourier analysis (FA). However, models based on FA may not have a clear insight too the instability reasons, whereas SS based models with system poles and zeros have a clear insight to the system stability information. In this paper, we introduce three methods to estimate system parameters for LSI EO imaging systems using SS based modeling. These methods include batch processing version of least squares (LS) estimation, recursive version of LS estimation, and sliding window LS estimation. The accuracy of the developed methods was tested using input and output signals of simulated LSI systems. First, LSI systems with various system parameters (poles and zeros) were simulated, which were then used to generate output signals for a set of random input signals, with each input signal value representing the average of an image. Then, these input and output signals were used to estimate systems employing SS and FA based modeling. Further, the estimated systems were used to generate output signals for a new set of input signals. For any given input signal, output signals generated by both systems were compared for similarities and signal-to-noise ratio (SNR). Results show that SS based models generate output signals that have higher SNR values. In addition, developed methods were tested against the simulated data and results show promise for development of models for estimating more complicated systems (e.g., non-linear system).

  3. Life cycle cost modeling of conceptual space vehicles

    Science.gov (United States)

    Ebeling, Charles

    1993-01-01

    This paper documents progress to date by the University of Dayton on the development of a life cycle cost model for use during the conceptual design of new launch vehicles and spacecraft. This research is being conducted under NASA Research Grant NAG-1-1327. This research effort changes the focus from that of the first two years in which a reliability and maintainability model was developed to the initial development of a life cycle cost model. Cost categories are initially patterned after NASA's three axis work breakdown structure consisting of a configuration axis (vehicle), a function axis, and a cost axis. The focus will be on operations and maintenance costs and other recurring costs. Secondary tasks performed concurrent with the development of the life cycle costing model include continual support and upgrade of the R&M model. The primary result of the completed research will be a methodology and a computer implementation of the methodology to provide for timely cost analysis in support of the conceptual design activities. The major objectives of this research are: to obtain and to develop improved methods for estimating manpower, spares, software and hardware costs, facilities costs, and other cost categories as identified by NASA personnel; to construct a life cycle cost model of a space transportation system for budget exercises and performance-cost trade-off analysis during the conceptual and development stages; to continue to support modifications and enhancements to the R&M model; and to continue to assist in the development of a simulation model to provide an integrated view of the operations and support of the proposed system.

  4. Equivalence and Differences between Structural Equation Modeling and State-Space Modeling Techniques

    Science.gov (United States)

    Chow, Sy-Miin; Ho, Moon-ho R.; Hamaker, Ellen L.; Dolan, Conor V.

    2010-01-01

    State-space modeling techniques have been compared to structural equation modeling (SEM) techniques in various contexts but their unique strengths have often been overshadowed by their similarities to SEM. In this article, we provide a comprehensive discussion of these 2 approaches' similarities and differences through analytic comparisons and…

  5. Action and Language Mechanisms in the Brain: Data, Models and Neuroinformatics

    DEFF Research Database (Denmark)

    Arbib, Michael A.; Bonaiuto, James J.; Bornkessel-Schlesewsky, Ina

    2014-01-01

    We assess the challenges of studying action and language mechanisms in the brain, both singly and in relation to each other to provide a novel perspective on neuroinformatics, integrating the development of databases for encoding - separately or together - neurocomputational models and empirical...

  6. Toward a Reconceptualization of Communication Cues to Action in the Health Belief Model: HIV Test Counseling.

    Science.gov (United States)

    Mattson, Marifran

    1999-01-01

    Examines the persuasive communication of HIV test counselors as cues to action in clients' decisions to practice safer sex. Indicates hypothesized relationships inherent in the Health Belief Model were not supported for the pre-HIV test survey, but the post-HIV test survey reported compliance with safer-sex recommendations. Finds use of certain…

  7. Model parameters of technical and tactical actions in the competitive activities of volleyball players

    Directory of Open Access Journals (Sweden)

    Doroshenko E.Iu.

    2013-10-01

    Full Text Available The application of modeling of technical and tactical actions as one of the leading components of the control system of competitive activities of highly skilled volleyball players. It is show that the proposed modeling techniques can generate the optimum orientation of the training process with the use of specialized tools at different stages of the annual cycle of training. In a study based on official statistics volleyball tournament World League in 2012 years. It is recommended to be oriented on the followings model indexes of actions of command and sportsmen: general amount of the collected glasses (170 - 190; amount of glasses, collected in an attack (139 - 157; amount of glasses, collected at blocking (12 - 24; amount of glasses, collected from a serve (9 - 17; the middle index of efficiency is protective actions (at the reception of ball from a serve -58,29%. It is shown that the performance of technical and tactical actions can be used as a model in the management of the process of training and competitive volleyball elite athletes.

  8. Citizens' Perceptions of Flood Hazard Adjustments: An Application of the Protective Action Decision Model

    Science.gov (United States)

    Terpstra, Teun; Lindell, Michael K.

    2013-01-01

    Although research indicates that adoption of flood preparations among Europeans is low, only a few studies have attempted to explain citizens' preparedness behavior. This article applies the Protective Action Decision Model (PADM) to explain flood preparedness intentions in the Netherlands. Survey data ("N" = 1,115) showed that…

  9. The Implementation of Models-Based Practice in Physical Education through Action Research

    Science.gov (United States)

    Casey, Ashley; Dyson, Ben

    2009-01-01

    The purpose of this study was to explore the use of action research as a framework to investigate cooperative learning and tactical games as instructional models in physical education (PE). The teacher/researcher taught a tennis unit using a combination of Cooperative Learning and Teaching Games for Understanding to three classes of boys aged…

  10. An action-learning model to assist Circuit Teams to support School ...

    African Journals Online (AJOL)

    We report on the construction of a theoretical model to assist Circuit Teams to support School Management Teams of underperforming high schools towards whole-school development in which these improvement plans play a central role. We followed an action research design, employing qualitative data generation and ...

  11. A model of film deformation and rupture under the action of thermo-capillary forces

    NARCIS (Netherlands)

    V. Pukhnachev; S. Dubinkina (Svetlana)

    2006-01-01

    htmlabstractA model of the deformation of a free weightless liquid film with rims fixed at a plane contour and subject to the action of thermocapillary forces is investigated. The film free-surface temperature is assumed to be a known function of the coordinates and time. The equation describing the

  12. Artist-Teachers' In-Action Mental Models While Teaching Visual Arts

    Science.gov (United States)

    Russo-Zimet, Gila

    2017-01-01

    Studies have examined the assumption that teachers have previous perceptions, beliefs and knowledge about learning (Cochran-Smith & Villegas, 2015). This study presented the In-Action Mental Model of twenty leading artist-teachers while teaching Visual Arts in three Israeli art institutions of higher Education. Data was collected in two…

  13. The Action--Reflection--Modelling (ARM) Pedagogical Approach for Teacher Education: A Malaysia-UK Project

    Science.gov (United States)

    Jarvis, Joy; Dickerson, Claire; Thomas, Kit; Graham, Sally

    2014-01-01

    This article presents the Action--Reflection--Modelling (ARM) pedagogical approach for teacher education developed during a Malaysia-UK collaborative project to construct a Bachelor of Education (Honours) degree programme in Primary Mathematics, with English and Health and Physical Education as minor subjects. The degree programme was written…

  14. Action and Language Mechanisms in the Brain: Data, Models and Neuroinformatics

    Science.gov (United States)

    Bonaiuto, James J.; Bornkessel-Schlesewsky, Ina; Kemmerer, David; MacWhinney, Brian; Nielsen, Finn Årup; Oztop, Erhan

    2014-01-01

    We assess the challenges of studying action and language mechanisms in the brain, both singly and in relation to each other to provide a novel perspective on neuroinformatics, integrating the development of databases for encoding – separately or together – neurocomputational models and empirical data that serve systems and cognitive neuroscience. PMID:24234916

  15. Using the Knowledge to Action Process Model to Incite Clinical Change

    Science.gov (United States)

    Petzold, Anita; Korner-Bitensky, Nicol; Menon, Anita

    2010-01-01

    Introduction: Knowledge translation (KT) has only recently emerged in the field of rehabilitation with attention on creating effective KT interventions to increase clinicians' knowledge and use of evidence-based practice (EBP). The uptake of EBP is a complex process that can be facilitated by the use of the Knowledge to Action Process model. This…

  16. Toward an integrative social identity model of collective action : A quantitative research synthesis of three socio-psychological perspectives

    NARCIS (Netherlands)

    Van Zomeren, M.; Postmes, T.; Spears, R.

    An integrative social identity model of collective action (SIMCA) is developed that incorporates 3 socio-psychological perspectives on collective action. Three meta-analyses synthesized a total of 182 effects of perceived injustice, efficacy, and identity on collective action (corresponding to these

  17. Human Factors Research for Space Exploration: Measurement, Modeling, and Mitigation

    Science.gov (United States)

    Kaiser, Mary K.; Allen, Christopher S.; Barshi, Immanuel; Billman, Dorrit; Holden, Kritina L.

    2010-01-01

    As part of NASA's Human Research Program, the Space Human Factors Engineering Project serves as the bridge between Human Factors research and Human Spaceflight applications. Our goal is to be responsive to the operational community while addressing issues at a sufficient level of abstraction to ensure that our tools and solutions generalize beyond the point design. In this panel, representatives from four of our research domains will discuss the challenges they face in solving current problems while also enabling future capabilities. Historically, engineering-dominated organizations have tended to view good Human Factors (HF) as a desire rather than a requirement in system design and development. Our field has made significant gains in the past decade, however; the Department of Defense, for example, now recognizes Human-System Integration (HSI), of which HF is a component, as an integral part of their divisions hardware acquisition processes. And our own agency was far more accepting of HF/HSI requirements during the most recent vehicle systems definition than in any prior cycle. Nonetheless, HF subject matter experts at NASA often find themselves in catch up mode... coping with legacy systems (hardware and software) and procedures that were designed with little regard for the human element, and too often with an attitude of we can deal with any operator issues during training. Our challenge, then, is to segregate the true knowledge gaps in Space Human Factors from the prior failures to incorporate best (or even good) HF design principles. Further, we strive to extract the overarching core HF issues from the point-design-specific concerns that capture the operators (and managers) attention. Generally, our approach embraces a 3M approach to Human Factors: Measurement, Modeling, and Mitigation. Our first step is to measure human performance, to move from subjective anecdotes to objective, quantified data. Next we model the phenomenon, using appropriate methods in

  18. Developing a new model for cross-cultural research: synthesizing the Health Belief Model and the Theory of Reasoned Action.

    Science.gov (United States)

    Poss, J E

    2001-06-01

    This article discusses the development of a new model representing the synthesis of two models that are often used to study health behaviors: the Health Belief Model and the Theory of Reasoned Action. The new model was developed as the theoretic framework for an investigation of the factors affecting participation by Mexican migrant workers in tuberculosis screening. Development of the synthesized model evolved from the concern that models used to investigate health-seeking behaviors of mainstream Anglo groups in the United States might not be appropriate for studying migrant workers or persons from other cultural backgrounds.

  19. D-brane effective action and tachyon condensation in topological minimal models

    CERN Document Server

    Herbst, Manfred; Lerche, Wolfgang; Herbst, Manfred; Lazaroiu, Calin-Iuliu; Lerche, Wolfgang

    2005-01-01

    We study D-brane moduli spaces and tachyon condensation in B-type topological minimal models and their massive deformations. We show that any B-type brane is isomorphic with a direct sum of `minimal' branes, and that its moduli space is stratified according to the type of such decompositions. Using the Landau-Ginzburg formulation, we propose a closed formula for the effective deformation potential, defined as the generating function of tree-level open string amplitudes in the presence of D-branes. This provides a direct link to the categorical description, and can be formulated in terms of holomorphic matrix models. We also check that the critical locus of this potential reproduces the D-branes' moduli space as expected from general considerations. Using these tools, we perform a detailed analysis of a few examples, for which we obtain a complete algebro-geometric description of moduli spaces and strata.

  20. A Taxonomic Reduced-Space Pollen Model for Paleoclimate Reconstruction

    Science.gov (United States)

    Wahl, E. R.; Schoelzel, C.

    2010-12-01

    Paleoenvironmental reconstruction from fossil pollen often attempts to take advantage of the rich taxonomic diversity in such data. Here, a taxonomically "reduced-space" reconstruction model is explored that would be parsimonious in introducing parameters needing to be estimated within a Bayesian Hierarchical Modeling context. This work involves a refinement of the traditional pollen ratio method. This method is useful when one (or a few) dominant pollen type(s) in a region have a strong positive correlation with a climate variable of interest and another (or a few) dominant pollen type(s) have a strong negative correlation. When, e.g., counts of pollen taxa a and b (r >0) are combined with pollen types c and d (r logistic generalized linear model (GLM). The GLM can readily model this relationship in the forward form, pollen = g(climate), which is more physically realistic than inverse models often used in paleoclimate reconstruction [climate = f(pollen)]. The specification of the model is: rnum Bin(n,p), where E(r|T) = p = exp(η)/[1+exp(η)], and η = α + β(T); r is the pollen ratio formed as above, rnum is the ratio numerator, n is the ratio denominator (i.e., the sum of pollen counts), the denominator-specific count is (n - rnum), and T is the temperature at each site corresponding to a specific value of r. Ecological and empirical screening identified the model (Spruce+Birch) / (Spruce+Birch+Oak+Hickory) for use in temperate eastern N. America. α and β were estimated using both "traditional" and Bayesian GLM algorithms (in R). Although it includes only four pollen types, the ratio model yields more explained variation ( 80%) in the pollen-temperature relationship of the study region than a 64-taxon modern analog technique (MAT). Thus, the new pollen ratio method represents an information-rich, reduced space data model that can be efficiently employed in a BHM framework. The ratio model can directly reconstruct past temperature by solving the GLM equations

  1. SOLUTION OF MATHEMATICAL MODEL FOR TRACKED VEHICLE MOVEMENT UNDER DIFFERENT CONTROL ACTIONS

    Directory of Open Access Journals (Sweden)

    S. Volosnikov

    2017-06-01

    Full Text Available The paper presents a solution to the mathematical model of the caterpillar platform motion in the process of going into corner at various speed of movement. The presented model made it possible to obtain characteristic trajectories of a caterpillar platform in a turn for different road conditions and control actions. The «steering wheel» and «levers», which are most widely used in turn control systems, are considered as controls for the caterpillar platform.

  2. Numerical Models for Sound Propagation in Long Spaces

    Science.gov (United States)

    Lai, Chenly Yuen Cheung

    Both reverberation time and steady-state sound field are the key elements for assessing the acoustic condition in an enclosed space. They affect the noise propagation, speech intelligibility, clarity index, and definition. Since the sound field in a long space is non diffuse, classical room acoustics theory does not apply in this situation. The ray tracing technique and the image source methods are two common models to fathom both reverberation time and steady-state sound field in long enclosures nowadays. Although both models can give an accurate estimate of reverberation times and steady-state sound field directly or indirectly, they often involve time-consuming calculations. In order to simplify the acoustic consideration, a theoretical formulation has been developed for predicting both steady-state sound fields and reverberation times in street canyons. The prediction model is further developed to predict the steady-state sound field in a long enclosure. Apart from the straight long enclosure, there are other variations such as a cross junction, a long enclosure with a T-intersection, an U-turn long enclosure. In the present study, an theoretical and experimental investigations were conducted to develop formulae for predicting reverberation times and steady-state sound fields in a junction of a street canyon and in a long enclosure with T-intersection. The theoretical models are validated by comparing the numerical predictions with published experimental results. The theoretical results are also compared with precise indoor measurements and large-scale outdoor experimental results. In all of previous acoustical studies related to long enclosure, most of the studies are focused on the monopole sound source. Besides non-directional noise source, many noise sources in long enclosure are dipole like, such as train noise and fan noise. In order to study the characteristics of directional noise sources, a review of available dipole source was conducted. A dipole was

  3. Improved Nuclear Reactor and Shield Mass Model for Space Applications

    Science.gov (United States)

    Robb, Kevin

    2004-01-01

    New technologies are being developed to explore the distant reaches of the solar system. Beyond Mars, solar energy is inadequate to power advanced scientific instruments. One technology that can meet the energy requirements is the space nuclear reactor. The nuclear reactor is used as a heat source for which a heat-to-electricity conversion system is needed. Examples of such conversion systems are the Brayton, Rankine, and Stirling cycles. Since launch cost is proportional to the amount of mass to lift, mass is always a concern in designing spacecraft. Estimations of system masses are an important part in determining the feasibility of a design. I worked under Michael Barrett in the Thermal Energy Conversion Branch of the Power & Electric Propulsion Division. An in-house Closed Cycle Engine Program (CCEP) is used for the design and performance analysis of closed-Brayton-cycle energy conversion systems for space applications. This program also calculates the system mass including the heat source. CCEP uses the subroutine RSMASS, which has been updated to RSMASS-D, to estimate the mass of the reactor. RSMASS was developed in 1986 at Sandia National Laboratories to quickly estimate the mass of multi-megawatt nuclear reactors for space applications. In response to an emphasis for lower power reactors, RSMASS-D was developed in 1997 and is based off of the SP-100 liquid metal cooled reactor. The subroutine calculates the mass of reactor components such as the safety systems, instrumentation and control, radiation shield, structure, reflector, and core. The major improvements in RSMASS-D are that it uses higher fidelity calculations, is easier to use, and automatically optimizes the systems mass. RSMASS-D is accurate within 15% of actual data while RSMASS is only accurate within 50%. My goal this summer was to learn FORTRAN 77 programming language and update the CCEP program with the RSMASS-D model.

  4. 'We need to get together and make ourselves heard': Everyday online spaces as incubators of political action

    NARCIS (Netherlands)

    Graham, Todd; Jackson, Daniel; Wright, Scott

    2016-01-01

    This article examines how, and to what extent, and how, people engaging in political talk in ‘non-political’ online discussion forums (focusing on parenting, personal finance and popular culture) – online lifestyle communities – leads to political (or personal) action or calls-to-action. The

  5. Spooky action at a distance the phenomenon that reimagines space and time, and what it means for black holes, the big bang, and theories of everything

    CERN Document Server

    Musser, George

    2015-01-01

    What is space? It isn't a question that most of us normally stop to ask. Space is the venue of physics; it's where things exist, where they move and take shape. Yet over the past few decades, physicists have discovered a phenomenon that operates outside the confines of space and time. The phenomenon, the ability of one particle to affect another instantly across the vastness of space appears to be almost magical. Einstein grappled with this oddity and couldn't quite resolve it, describing it as "spooky action at a distance." But this strange occurrence has direct connections to black holes, particle collisions, and even the workings of gravity. If space isn't what we thought it was, then what is it? In Spooky Action at a Distance, George Musser sets out to answer that question, offering a provocative exploration of non locality and a celebration of the scientists who are trying to understand it. Musser guides us on an epic journey of scientific discovery into the lives of experimental physicists observing par...

  6. On modelling of physical effects accompanying the propagation of action potentials in nerve fibres

    CERN Document Server

    Engelbrecht, Jüri; Tamm, Kert; Laasmaa, Martin; Vendelin, Marko

    2016-01-01

    The recent theoretical and experimental studies have revealed many details of signal propagation in nervous systems. In this paper an attempt is made to unify various mathematical models which describe the signal propagation in nerve fibres. The analysis of existing single models permits to select the leading physiological effects. As a result, a more general mathematical model is described based on the coupling of action potentials with mechanical waves in a nerve fibre. The crucial issue is how to model coupling effects which are strongly linked to the ion currents through biomembranes.

  7. Logistic regression models for polymorphic and antagonistic pleiotropic gene action on human aging and longevity

    DEFF Research Database (Denmark)

    Tan, Qihua; Bathum, L; Christiansen, L

    2003-01-01

    In this paper, we apply logistic regression models to measure genetic association with human survival for highly polymorphic and pleiotropic genes. By modelling genotype frequency as a function of age, we introduce a logistic regression model with polytomous responses to handle the polymorphic...... situation. Genotype and allele-based parameterization can be used to investigate the modes of gene action and to reduce the number of parameters, so that the power is increased while the amount of multiple testing minimized. A binomial logistic regression model with fractional polynomials is used to capture...

  8. Cognition in Space Workshop. 1; Metrics and Models

    Science.gov (United States)

    Woolford, Barbara; Fielder, Edna

    2005-01-01

    "Cognition in Space Workshop I: Metrics and Models" was the first in a series of workshops sponsored by NASA to develop an integrated research and development plan supporting human cognition in space exploration. The workshop was held in Chandler, Arizona, October 25-27, 2004. The participants represented academia, government agencies, and medical centers. This workshop addressed the following goal of the NASA Human System Integration Program for Exploration: to develop a program to manage risks due to human performance and human error, specifically ones tied to cognition. Risks range from catastrophic error to degradation of efficiency and failure to accomplish mission goals. Cognition itself includes memory, decision making, initiation of motor responses, sensation, and perception. Four subgoals were also defined at the workshop as follows: (1) NASA needs to develop a human-centered design process that incorporates standards for human cognition, human performance, and assessment of human interfaces; (2) NASA needs to identify and assess factors that increase risks associated with cognition; (3) NASA needs to predict risks associated with cognition; and (4) NASA needs to mitigate risk, both prior to actual missions and in real time. This report develops the material relating to these four subgoals.

  9. Converting Boundary Representation Solid Models to Half-Space Representation Models for Monte Carlo Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Davis JE, Eddy MJ, Sutton TM, Altomari TJ

    2007-03-01

    Solid modeling computer software systems provide for the design of three-dimensional solid models used in the design and analysis of physical components. The current state-of-the-art in solid modeling representation uses a boundary representation format in which geometry and topology are used to form three-dimensional boundaries of the solid. The geometry representation used in these systems is cubic B-spline curves and surfaces--a network of cubic B-spline functions in three-dimensional Cartesian coordinate space. Many Monte Carlo codes, however, use a geometry representation in which geometry units are specified by intersections and unions of half-spaces. This paper describes an algorithm for converting from a boundary representation to a half-space representation.

  10. GERMcode: A Stochastic Model for Space Radiation Risk Assessment

    Science.gov (United States)

    Kim, Myung-Hee Y.; Ponomarev, Artem L.; Cucinotta, Francis A.

    2012-01-01

    A new computer model, the GCR Event-based Risk Model code (GERMcode), was developed to describe biophysical events from high-energy protons and high charge and energy (HZE) particles that have been studied at the NASA Space Radiation Laboratory (NSRL) for the purpose of simulating space radiation biological effects. In the GERMcode, the biophysical description of the passage of HZE particles in tissue and shielding materials is made with a stochastic approach that includes both particle track structure and nuclear interactions. The GERMcode accounts for the major nuclear interaction processes of importance for describing heavy ion beams, including nuclear fragmentation, elastic scattering, and knockout-cascade processes by using the quantum multiple scattering fragmentation (QMSFRG) model. The QMSFRG model has been shown to be in excellent agreement with available experimental data for nuclear fragmentation cross sections. For NSRL applications, the GERMcode evaluates a set of biophysical properties, such as the Poisson distribution of particles or delta-ray hits for a given cellular area and particle dose, the radial dose on tissue, and the frequency distribution of energy deposition in a DNA volume. By utilizing the ProE/Fishbowl ray-tracing analysis, the GERMcode will be used as a bi-directional radiation transport model for future spacecraft shielding analysis in support of Mars mission risk assessments. Recent radiobiological experiments suggest the need for new approaches to risk assessment that include time-dependent biological events due to the signaling times for activation and relaxation of biological processes in cells and tissue. Thus, the tracking of the temporal and spatial distribution of events in tissue is a major goal of the GERMcode in support of the simulation of biological processes important in GCR risk assessments. In order to validate our approach, basic radiobiological responses such as cell survival curves, mutation, chromosomal

  11. Making Faces - State-Space Models Applied to Multi-Modal Signal Processing

    DEFF Research Database (Denmark)

    Lehn-Schiøler, Tue

    2005-01-01

    The two main focus areas of this thesis are State-Space Models and multi modal signal processing. The general State-Space Model is investigated and an addition to the class of sequential sampling methods is proposed. This new algorithm is denoted as the Parzen Particle Filter. Furthermore...... optimizer can be applied to speed up convergence. The linear version of the State-Space Model, the Kalman Filter, is applied to multi modal signal processing. It is demonstrated how a State-Space Model can be used to map from speech to lip movements. Besides the State-Space Model and the multi modal...

  12. 75 FR 10694 - Airworthiness Directives; AeroSpace Technologies of Australia Pty Ltd Models N22B, N22S, and N24A...

    Science.gov (United States)

    2010-03-09

    ...; ] DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; AeroSpace Technologies of Australia Pty Ltd Models N22B, N22S, and N24A Airplanes AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice of proposed rulemaking...

  13. PRO-ECOLOGICAL ACTIONS AND CONSUMER CHOICES IN THE MODEL OF RESPONSIBLE BUSINESS

    Directory of Open Access Journals (Sweden)

    Katarzyna Olejniczak

    2015-09-01

    Full Text Available The current farming conditions cause that recent social and environmental aspects of management play an important role for the functioning of modern enterprises. This results from the fact that on the one hand the activities of modern enterprises are determined by the surroundings’ increasing complexity, on the other hand the growing demands of various groups of stakeholders build company’s success based not only on a quest to maximize their profi t, but primarily on taking the responsibility for the consequences of their actions. Additionally, the growing awareness of consumers makes more and more enterprises implement the concept of corporate social responsibility (CSR in their actions. For this reason, it is important to discuss about the actions and choices of consumers in the model of CSR. The aim of this article is to present the results of the research on customers‘s environmentally conscious activities and choices.

  14. Teaching Ethics in Higher Education Using the Values – Issues – Action (VIA Model

    Directory of Open Access Journals (Sweden)

    Crystal R Chambers

    2016-01-01

    Full Text Available Ethics content within higher education graduate programs can help higher education students as emerging leaders become more thoughtful about the decision making process. The purpose of the present manuscript is to explore one vehicle through which current and future higher education leaders can actively contemplate their values and how their values influence their actions when faced with an ethical challenge. The Values – Issue – Action (VIA Model for Ethical Decision Making is a tool for both classroom use and professional reflection through which one can reflect on their values (V and how those values shape how they perceive issues (I, and in turn shape their actions (A. Implications for teaching, learning, and practice are discussed.

  15. Review of the Space Mapping Approach to Engineering Optimization and Modeling

    DEFF Research Database (Denmark)

    Bakr, M. H.; Bandler, J. W.; Madsen, Kaj

    2000-01-01

    We review the Space Mapping (SM) concept and its applications in engineering optimization and modeling. The aim of SM is to avoid computationally expensive calculations encountered in simulating an engineering system. The existence of less accurate but fast physically-based models is exploited. S......-based Modeling (SMM). These include Space Derivative Mapping (SDM), Generalized Space Mapping (GSM) and Space Mapping-based Neuromodeling (SMN). Finally, we address open points for research and future development....

  16. Flexible space structure model reduction by modal cost analysis

    Science.gov (United States)

    Skelton, R. E.; Hughes, P. C.

    1979-01-01

    It is noted that reduced models and reduced controllers for flexible space structures are obtained by retaining those modes which make the greatest contribution to quadratic control objectives. Attention is given to the relative importance of damping, frequency and mode shapes in the mode truncation decisions for the following control objectives: attitude control, vibration suppression and figure control. It is also shown that using Modal Cost Analysis (MCA) on the closed loop modes of the optimally controlled system allows the construction of reduced control policies which feedback only those closed loop coordinates which are most critical to the quadratic control performance criterion. In this manner, the modes which need to be controlled are deduced from truncations of the optimal controller.

  17. Quantitative Risk Modeling of Fire on the International Space Station

    Science.gov (United States)

    Castillo, Theresa; Haught, Megan

    2014-01-01

    The International Space Station (ISS) Program has worked to prevent fire events and to mitigate their impacts should they occur. Hardware is designed to reduce sources of ignition, oxygen systems are designed to control leaking, flammable materials are prevented from flying to ISS whenever possible, the crew is trained in fire response, and fire response equipment improvements are sought out and funded. Fire prevention and mitigation are a top ISS Program priority - however, programmatic resources are limited; thus, risk trades are made to ensure an adequate level of safety is maintained onboard the ISS. In support of these risk trades, the ISS Probabilistic Risk Assessment (PRA) team has modeled the likelihood of fire occurring in the ISS pressurized cabin, a phenomenological event that has never before been probabilistically modeled in a microgravity environment. This paper will discuss the genesis of the ISS PRA fire model, its enhancement in collaboration with fire experts, and the results which have informed ISS programmatic decisions and will continue to be used throughout the life of the program.

  18. Exploring the Model Design Space for Battery Health Management

    Science.gov (United States)

    Saha, Bhaskar; Quach, Cuong Chi; Goebel, Kai Frank

    2011-01-01

    Battery Health Management (BHM) is a core enabling technology for the success and widespread adoption of the emerging electric vehicles of today. Although battery chemistries have been studied in detail in literature, an accurate run-time battery life prediction algorithm has eluded us. Current reliability-based techniques are insufficient to manage the use of such batteries when they are an active power source with frequently varying loads in uncertain environments. The amount of usable charge of a battery for a given discharge profile is not only dependent on the starting state-of-charge (SOC), but also other factors like battery health and the discharge or load profile imposed. This paper presents a Particle Filter (PF) based BHM framework with plug-and-play modules for battery models and uncertainty management. The batteries are modeled at three different levels of granularity with associated uncertainty distributions, encoding the basic electrochemical processes of a Lithium-polymer battery. The effects of different choices in the model design space are explored in the context of prediction performance in an electric unmanned aerial vehicle (UAV) application with emulated flight profiles.

  19. Forecasting seasonal influenza with a state-space SIR model.

    Science.gov (United States)

    Osthus, Dave; Hickmann, Kyle S; Caragea, Petruţa C; Higdon, Dave; Del Valle, Sara Y

    2017-03-01

    Seasonal influenza is a serious public health and societal problem due to its consequences resulting from absenteeism, hospitalizations, and deaths. The overall burden of influenza is captured by the Centers for Disease Control and Prevention's influenza-like illness network, which provides invaluable information about the current incidence. This information is used to provide decision support regarding prevention and response efforts. Despite the relatively rich surveillance data and the recurrent nature of seasonal influenza, forecasting the timing and intensity of seasonal influenza in the U.S. remains challenging because the form of the disease transmission process is uncertain, the disease dynamics are only partially observed, and the public health observations are noisy. Fitting a probabilistic state-space model motivated by a deterministic mathematical model [a susceptible-infectious-recovered (SIR) model] is a promising approach for forecasting seasonal influenza while simultaneously accounting for multiple sources of uncertainty. A significant finding of this work is the importance of thoughtfully specifying the prior, as results critically depend on its specification. Our conditionally specified prior allows us to exploit known relationships between latent SIR initial conditions and parameters and functions of surveillance data. We demonstrate advantages of our approach relative to alternatives via a forecasting comparison using several forecast accuracy metrics.

  20. REVEL: A model for Recent plate velocities from space geodesy

    Science.gov (United States)

    Sella, Giovanni F.; Dixon, Timothy H.; Mao, Ailin

    2002-04-01

    We present a new global model for Recent plate velocities, REVEL, describing the relative velocities of 19 plates and continental blocks. The model is derived from publicly available space geodetic (primarily GPS) data for the period 1993-2000. We include an independent and rigorous estimate for GPS velocity uncertainties to assess plate rigidity and propagate these uncertainties to the velocity estimates. The velocity fields for North America, Eurasia, and Antarctica clearly show the effects of glacial isostatic adjustment, and Australia appears to depart from rigid plate behavior in a manner consistent with the mapped intraplate stress field. Two thirds of tested plate pairs agree with the NUVEL-1A geologic (3 Myr average) velocities within uncertainties. Three plate pairs (Caribbean-North America, Caribbean-South America, and North America-Pacific) exhibit significant differences between the geodetic and geologic model that may reflect systematic errors in NUVEL-1A due to the use of seafloor magnetic rate data that do not reflect the full plate rate because of tectonic complexities. Most other differences probably reflect real velocity changes over the last few million years. Several plate pairs (Arabia-Eurasia, Arabia-Nubia, Eurasia-India) move more slowly than the 3 Myr NUVEL-1A average, perhaps reflecting long-term deceleration associated with continental collision. Several other plate pairs, including Nazca-Pacific, Nazca-South America and Nubia-South America, are experiencing slowing that began ~25 Ma, the beginning of the current phase of Andean crustal shortening.

  1. A Pro-Environmental Reasoned Action Model for Measuring Citizens’ Intentions regarding Ecolabel Product Usage

    Directory of Open Access Journals (Sweden)

    Reny Nadlifatin

    2016-11-01

    Full Text Available Ecolabel products are one approach towards environmental sustainability. Ecolabel programs have been socialized by governments all over the world to reduce environmental harm caused by the daily life cycles of the products that citizens use. The present study was aimed at measuring citizens’ behavior intention (BI regarding ecolabel product usage. An extended theory of reasoned action (TRA, namely that of pro-environmental reasoned action (PERA, is used as the predictor model. A total of 213 questionnaire data, collected from citizens of Indonesia, was analyzed using structural equation modeling. The analysis results show that the PERA model is able to describe 68% of citizens’ BI regarding ecolabel product usage. The analysis results also reveal that attitude is a key determinant factor. Several practical suggestions based on the results can be used as input for policy makers and company management to consider in their efforts to increase citizens’ BI to use ecolabel products.

  2. NASA 3D Models: James Webb Space Telescope

    Data.gov (United States)

    National Aeronautics and Space Administration — The James Webb Space Telescope (JWST) will be a large infrared telescope with a 6.5-meter primary mirror. The project is working to a 2018 launch date. The JWST will...

  3. Observational Model for Precision Astrometry with the Space Interferometry Mission

    National Research Council Canada - National Science Library

    Turyshev, Slava G; Milman, Mark H

    2000-01-01

    The Space Interferometry Mission (SIM) is a space-based 10-m baseline Michelson optical interferometer operating in the visible waveband that is designed to achieve astrometric accuracy in the single digits of the microarcsecond domain...

  4. Simulating Emerging Space Industries with Agent-Based Modeling Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Vision for Space Exploration (VSE) calls for encouraging commercial participation as a top-level objective. Given current and future commercial activities, how...

  5. A phantom axon setup for validating models of action potential recordings.

    Science.gov (United States)

    Rossel, Olivier; Soulier, Fabien; Bernard, Serge; Guiraud, David; Cathébras, Guy

    2016-08-01

    Electrode designs and strategies for electroneurogram recordings are often tested first by computer simulations and then by animal models, but they are rarely implanted for long-term evaluation in humans. The models show that the amplitude of the potential at the surface of an axon is higher in front of the nodes of Ranvier than at the internodes; however, this has not been investigated through in vivo measurements. An original experimental method is presented to emulate a single fiber action potential in an infinite conductive volume, allowing the potential of an axon to be recorded at both the nodes of Ranvier and the internodes, for a wide range of electrode-to-fiber radial distances. The paper particularly investigates the differences in the action potential amplitude along the longitudinal axis of an axon. At a short radial distance, the action potential amplitude measured in front of a node of Ranvier is two times larger than in the middle of two nodes. Moreover, farther from the phantom axon, the measured action potential amplitude is almost constant along the longitudinal axis. The results of this new method confirm the computer simulations, with a correlation of 97.6 %.

  6. d-Lysergic Acid Diethylamide (LSD) as a Model of Psychosis: Mechanism of Action and Pharmacology.

    Science.gov (United States)

    De Gregorio, Danilo; Comai, Stefano; Posa, Luca; Gobbi, Gabriella

    2016-11-23

    d-Lysergic Acid Diethylamide (LSD) is known for its hallucinogenic properties and psychotic-like symptoms, especially at high doses. It is indeed used as a pharmacological model of psychosis in preclinical research. The goal of this review was to understand the mechanism of action of psychotic-like effects of LSD. We searched Pubmed, Web of Science, Scopus, Google Scholar and articles' reference lists for preclinical studies regarding the mechanism of action involved in the psychotic-like effects induced by LSD. LSD's mechanism of action is pleiotropic, primarily mediated by the serotonergic system in the Dorsal Raphe, binding the 5-HT2A receptor as a partial agonist and 5-HT1A as an agonist. LSD also modulates the Ventral Tegmental Area, at higher doses, by stimulating dopamine D₂, Trace Amine Associate receptor 1 (TAAR₁) and 5-HT2A. More studies clarifying the mechanism of action of the psychotic-like symptoms or psychosis induced by LSD in humans are needed. LSD's effects are mediated by a pleiotropic mechanism involving serotonergic, dopaminergic, and glutamatergic neurotransmission. Thus, the LSD-induced psychosis is a useful model to test the therapeutic efficacy of potential novel antipsychotic drugs, particularly drugs with dual serotonergic and dopaminergic (DA) mechanism or acting on TAAR₁ receptors.

  7. d-Lysergic Acid Diethylamide (LSD as a Model of Psychosis: Mechanism of Action and Pharmacology

    Directory of Open Access Journals (Sweden)

    Danilo De Gregorio

    2016-11-01

    Full Text Available d-Lysergic Acid Diethylamide (LSD is known for its hallucinogenic properties and psychotic-like symptoms, especially at high doses. It is indeed used as a pharmacological model of psychosis in preclinical research. The goal of this review was to understand the mechanism of action of psychotic-like effects of LSD. We searched Pubmed, Web of Science, Scopus, Google Scholar and articles’ reference lists for preclinical studies regarding the mechanism of action involved in the psychotic-like effects induced by LSD. LSD’s mechanism of action is pleiotropic, primarily mediated by the serotonergic system in the Dorsal Raphe, binding the 5-HT2A receptor as a partial agonist and 5-HT1A as an agonist. LSD also modulates the Ventral Tegmental Area, at higher doses, by stimulating dopamine D2, Trace Amine Associate receptor 1 (TAAR1 and 5-HT2A. More studies clarifying the mechanism of action of the psychotic-like symptoms or psychosis induced by LSD in humans are needed. LSD’s effects are mediated by a pleiotropic mechanism involving serotonergic, dopaminergic, and glutamatergic neurotransmission. Thus, the LSD-induced psychosis is a useful model to test the therapeutic efficacy of potential novel antipsychotic drugs, particularly drugs with dual serotonergic and dopaminergic (DA mechanism or acting on TAAR1 receptors.

  8. Dynamic Model Averaging in Large Model Spaces Using Dynamic Occam's Window.

    Science.gov (United States)

    Onorante, Luca; Raftery, Adrian E

    2016-01-01

    Bayesian model averaging has become a widely used approach to accounting for uncertainty about the structural form of the model generating the data. When data arrive sequentially and the generating model can change over time, Dynamic Model Averaging (DMA) extends model averaging to deal with this situation. Often in macroeconomics, however, many candidate explanatory variables are available and the number of possible models becomes too large for DMA to be applied in its original form. We propose a new method for this situation which allows us to perform DMA without considering the whole model space, but using a subset of models and dynamically optimizing the choice of models at each point in time. This yields a dynamic form of Occam's window. We evaluate the method in the context of the problem of nowcasting GDP in the Euro area. We find that its forecasting performance compares well with that of other methods.

  9. Dynamic Model Averaging in Large Model Spaces Using Dynamic Occam’s Window*

    Science.gov (United States)

    Onorante, Luca; Raftery, Adrian E.

    2015-01-01

    Bayesian model averaging has become a widely used approach to accounting for uncertainty about the structural form of the model generating the data. When data arrive sequentially and the generating model can change over time, Dynamic Model Averaging (DMA) extends model averaging to deal with this situation. Often in macroeconomics, however, many candidate explanatory variables are available and the number of possible models becomes too large for DMA to be applied in its original form. We propose a new method for this situation which allows us to perform DMA without considering the whole model space, but using a subset of models and dynamically optimizing the choice of models at each point in time. This yields a dynamic form of Occam’s window. We evaluate the method in the context of the problem of nowcasting GDP in the Euro area. We find that its forecasting performance compares well with that of other methods. PMID:26917859

  10. A model to inform management actions as a response to chytridiomycosis-associated decline

    Science.gov (United States)

    Converse, Sarah; Bailey, Larissa L.; Mosher, Brittany A.; Funk, W. Chris; Gerber, Brian D.; Muths, Erin L.

    2017-01-01

    Decision-analytic models provide forecasts of how systems of interest will respond to management. These models can be parameterized using empirical data, but sometimes require information elicited from experts. When evaluating the effects of disease in species translocation programs, expert judgment is likely to play a role because complete empirical information will rarely be available. We illustrate development of a decision-analytic model built to inform decision-making regarding translocations and other management actions for the boreal toad (Anaxyrus boreas boreas), a species with declines linked to chytridiomycosis caused by Batrachochytrium dendrobatidis (Bd). Using the model, we explored the management implications of major uncertainties in this system, including whether there is a genetic basis for resistance to pathogenic infection by Bd, how translocation can best be implemented, and the effectiveness of efforts to reduce the spread of Bd. Our modeling exercise suggested that while selection for resistance to pathogenic infectionDecision-analytic models provide forecasts of how systems of interest will respond to management. These models can be parameterized using empirical data, but sometimes require information elicited from experts. When evaluating the effects of disease in species translocation programs, expert judgment is likely to play a role because complete empirical information will rarely be available. We illustrate development of a decision-analytic model built to inform decision-making regarding translocations and other management actions for the boreal toad (Anaxyrus boreas boreas), a species with declines linked to chytridiomycosis caused by Batrachochytrium dendrobatidis (Bd). Using the model, we explored the management implications of major uncertainties in this system, including whether there is a genetic basis for resistance to pathogenic infection by Bd, how translocation can best be implemented, and the effectiveness of efforts to

  11. Modeling a snap-action, variable-delay switch controlling extrinsic cell death.

    Directory of Open Access Journals (Sweden)

    John G Albeck

    2008-12-01

    Full Text Available When exposed to tumor necrosis factor (TNF or TNF-related apoptosis-inducing ligand (TRAIL, a closely related death ligand and investigational therapeutic, cells enter a protracted period of variable duration in which only upstream initiator caspases are active. A subsequent and sudden transition marks activation of the downstream effector caspases that rapidly dismantle the cell. Thus, extrinsic apoptosis is controlled by an unusual variable-delay, snap-action switch that enforces an unambiguous choice between life and death. To understand how the extrinsic apoptosis switch functions in quantitative terms, we constructed a mathematical model based on a mass-action representation of known reaction pathways. The model was trained against experimental data obtained by live-cell imaging, flow cytometry, and immunoblotting of cells perturbed by protein depletion and overexpression. The trained model accurately reproduces the behavior of normal and perturbed cells exposed to TRAIL, making it possible to study switching mechanisms in detail. Model analysis shows, and experiments confirm, that the duration of the delay prior to effector caspase activation is determined by initiator caspase-8 activity and the rates of other reactions lying immediately downstream of the TRAIL receptor. Sudden activation of effector caspases is achieved downstream by reactions involved in permeabilization of the mitochondrial membrane and relocalization of proteins such as Smac. We find that the pattern of interactions among Bcl-2 family members, the partitioning of Smac from its binding partner XIAP, and the mechanics of pore assembly are all critical for snap-action control.

  12. Anisotropic compact star models in Karmarkar space time continuum

    Science.gov (United States)

    Fuloria, Pratibha

    2017-12-01

    In the present article, we have explored some new anisotropic compact star models by using embedded class one space time metric. We proceed our calculations by assuming a particular form of g_{rr} metric potential and solved for the other metric g_{tt} using Karmarkar condition. The matter density, radial pressure, tangential pressure, mass function, surface red-shift, anisotropy are all well behaved inside the fluid sphere. The solution satisfies all energy conditions i.e. strong energy condition, null energy condition, dominant energy condition and weak energy condition. The solution also satisfies the causality condition and can represent stable stellar fluid system as the adiabatic index Γ > 4/3 and the stability factor -1≤ vt2-vr2≤ 0 holds good inside the fluid sphere. We have framed our solution for two compact stars PSR J1614-2230 and SAX J1808.4-3658, which are well-behaved in all respects. The mass and radius of the compact stars PSR J1614-2230 and SAXJ1808.4-3658, obtained from the models are very close to the observational data proposed by Gangopadhyay et al. (Mon. Not. R. Astron. Soc. 431:3216, 2013) and Bhattacharya (2001) respectively.

  13. Space-time fluid mechanics computation of heart valve models

    Science.gov (United States)

    Takizawa, Kenji; Tezduyar, Tayfun E.; Buscher, Austin; Asada, Shohei

    2014-10-01

    Fluid mechanics computation of heart valves with an interface-tracking (moving-mesh) method was one of the classes of computations targeted in introducing the space-time (ST) interface tracking method with topology change (ST-TC). The ST-TC method is a new version of the Deforming-Spatial-Domain/Stabilized ST (DSD/SST) method. It can deal with an actual contact between solid surfaces in flow problems with moving interfaces, while still possessing the desirable features of interface-tracking methods, such as better resolution of the boundary layers. The DSD/SST method with effective mesh update can already handle moving-interface problems when the solid surfaces are in near contact or create near TC, if the "nearness" is sufficiently "near" for the purpose of solving the problem. That, however, is not the case in fluid mechanics of heart valves, as the solid surfaces need to be brought into an actual contact when the flow has to be completely blocked. Here we extend the ST-TC method to 3D fluid mechanics computation of heart valve models. We present computations for two models: an aortic valve with coronary arteries and a mechanical aortic valve. These computations demonstrate that the ST-TC method can bring interface-tracking accuracy to fluid mechanics of heart valves, and can do that with computational practicality.

  14. Networks and Mechanisms of Interdependence. Theoretical developments beyond the rational action model

    Directory of Open Access Journals (Sweden)

    González-Bailón, Sandra

    2009-12-01

    Full Text Available There is interdependence when the actions of an individual influence the decisions (and later actions of other individuals. This paper claims that social networks define the structure of that range of influence and unleash a number of mechanisms that go beyond those captured by rational action theory. Networks give access to the ideas and actions of other individuals, and this exposure determines the activation of thresholds, the timing of actions, and the emergence of contagion processes, informational cascades and epidemics. This paper sustains that rational action theory does not offer the necessary tools to model these processes if it is not inserted in a general theory of networks. This is especially the case in the context opened by new information and communication technologies, where the interdependence of individuals is acquiring greater empirical relevance.

    Existe interdependencia cuando las acciones de unos individuos influyen en las decisiones (y posteriores acciones de otros individuos. Este artículo sostiene que las redes sociales definen la estructura de ese espacio de influencia y desatan una serie de mecanismos de los que la teoría de la elección racional no puede dar cuenta. Las redes sociales abren acceso a las ideas y acciones de otros individuos, y esta exposición determina la satisfacción de umbrales, el tempo con en el que se llevan a cabo las acciones y la emergencia de procesos de contagio, cascadas de información y epidemias. Este artículo defiende que la teoría de la elección racional no ofrece las herramientas necesarias para modelizar tales procesos si no se inserta en una teoría general de redes. Éste es especialmente el caso en unos momentos en los que la interdependencia de individuos está adquiriendo, al amparo de las nuevas tecnologías, mayor relevancia empírica.

  15. Developing a Learning Progression for Number Sense Based on the Rule Space Model in China

    Science.gov (United States)

    Chen, Fu; Yan, Yue; Xin, Tao

    2017-01-01

    The current study focuses on developing the learning progression of number sense for primary school students, and it applies a cognitive diagnostic model, the rule space model, to data analysis. The rule space model analysis firstly extracted nine cognitive attributes and their hierarchy model from the analysis of previous research and the…

  16. Representative Model of the Learning Process in Virtual Spaces Supported by ICT

    Science.gov (United States)

    Capacho, José

    2014-01-01

    This paper shows the results of research activities for building the representative model of the learning process in virtual spaces (e-Learning). The formal basis of the model are supported in the analysis of models of learning assessment in virtual spaces and specifically in Dembo´s teaching learning model, the systemic approach to evaluating…

  17. Non-perturbative renormalization in coordinate space for N{sub f}=2 maximally twisted mass fermions with tree-level Symanzik improved gauge action

    Energy Technology Data Exchange (ETDEWEB)

    Cichy, Krzysztof [DESY, Zeuthen (Germany). NIC; Adam Mickiewicz Univ., Poznan (Poland). Faculty of Physics; Jansen, Karl [DESY, Zeuthen (Germany). NIC; Korcyl, Piotr [DESY, Zeuthen (Germany). NIC; Jagiellonian Univ., Krakow (Poland). M. Smoluchowski Inst. of Physics

    2012-07-15

    We present results of a lattice QCD application of a coordinate space renormalization scheme for the extraction of renormalization constants for flavour non-singlet bilinear quark operators. The method consists in the analysis of the small-distance behaviour of correlation functions in Euclidean space and has several theoretical and practical advantages, in particular: it is gauge invariant, easy to implement and has relatively low computational cost. The values of renormalization constants in the X-space scheme can be converted to the MS scheme via 4-loop continuum perturbative formulae. Our results for N{sub f}=2 maximally twisted mass fermions with tree-level Symanzik improved gauge action are compared to the ones from the RI-MOM scheme and show full agreement with this method. (orig.)

  18. Using the Benner intuitive-humanistic decision-making model in action: a case study.

    Science.gov (United States)

    Blum, Cynthia Ann

    2010-09-01

    Nurse educators make decisions that affect students in profound ways. This decision-making process may follow an intuitive-humanistic decision-making model. The author most connected with developing the intuitive model and the distinction between theoretical knowledge and experiential knowledge in the discipline of nursing is Patricia Benner (Thompson, 1999). Educators use intuition in forming judgments regarding educational planning. The educator may not be aware of subtleties that influence the decision but rely on a 'gut' instinct as they determine the appropriate action. Utilizing six key concepts identified by Dreyfus and Dreyfus (Benner and Tanner, 1987) this process utilizes what is known to the educator from previous situations to determine a course of action appropriate for the given situation. This paper describes a method one nursing educator used and identifies outcomes that could impact the career path for the student when determining if they were safe to continue in a practice based course. (c) 2010 Elsevier Ltd. All rights reserved.

  19. Modeling the Mass Action Dynamics of Metabolism with Fluctuation Theorems and Maximum Entropy

    Science.gov (United States)

    Cannon, William; Thomas, Dennis; Baxter, Douglas; Zucker, Jeremy; Goh, Garrett

    The laws of thermodynamics dictate the behavior of biotic and abiotic systems. Simulation methods based on statistical thermodynamics can provide a fundamental understanding of how biological systems function and are coupled to their environment. While mass action kinetic simulations are based on solving ordinary differential equations using rate parameters, analogous thermodynamic simulations of mass action dynamics are based on modeling states using chemical potentials. The latter have the advantage that standard free energies of formation/reaction and metabolite levels are much easier to determine than rate parameters, allowing one to model across a large range of scales. Bridging theory and experiment, statistical thermodynamics simulations allow us to both predict activities of metabolites and enzymes and use experimental measurements of metabolites and proteins as input data. Even if metabolite levels are not available experimentally, it is shown that a maximum entropy assumption is quite reasonable and in many cases results in both the most energetically efficient process and the highest material flux.

  20. Electrophysiological properties of computational human ventricular cell action potential models under acute ischemic conditions.

    Science.gov (United States)

    Dutta, Sara; Mincholé, Ana; Quinn, T Alexander; Rodriguez, Blanca

    2017-10-01

    Acute myocardial ischemia is one of the main causes of sudden cardiac death. The mechanisms have been investigated primarily in experimental and computational studies using different animal species, but human studies remain scarce. In this study, we assess the ability of four human ventricular action potential models (ten Tusscher and Panfilov, 2006; Grandi et al., 2010; Carro et al., 2011; O'Hara et al., 2011) to simulate key electrophysiological consequences of acute myocardial ischemia in single cell and tissue simulations. We specifically focus on evaluating the effect of extracellular potassium concentration and activation of the ATP-sensitive inward-rectifying potassium current on action potential duration, post-repolarization refractoriness, and conduction velocity, as the most critical factors in determining reentry vulnerability during ischemia. Our results show that the Grandi and O'Hara models required modifications to reproduce expected ischemic changes, specifically modifying the intracellular potassium concentration in the Grandi model and the sodium current in the O'Hara model. With these modifications, the four human ventricular cell AP models analyzed in this study reproduce the electrophysiological alterations in repolarization, refractoriness, and conduction velocity caused by acute myocardial ischemia. However, quantitative differences are observed between the models and overall, the ten Tusscher and modified O'Hara models show closest agreement to experimental data. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  1. Spatio-temporal tumour model for analysis and mechanism of action ...

    Indian Academy of Sciences (India)

    We have developed a one-dimensional tumour simulator to describe the biodistribution of chemotherapeutic drugs to a tumoral lesion and the tumour cell's response to therapy. A three-compartment model is used for drug dynamics within the tumour. The first compartment represents the extracellular space in which cells ...

  2. Pain-releasing action of platelet-activating factor (PAF) antagonists in neuropathic pain animal models and the mechanisms of action.

    Science.gov (United States)

    Motoyama, N; Morita, K; Kitayama, T; Shiraishi, S; Uezono, Y; Nishimura, F; Kanematsu, T; Dohi, T

    2013-09-01

    Platelet-activating factor (PAF) has been implicated in the pathology of neuropathic pain. Previous studies reported that PAF receptor (PAF-R) antagonists have varied anti-allodynia effects by route of administration and nerve injury models in rats. The present study elucidated the effectiveness of PAF antagonists against neuropathic pain in four different models of peripheral nerve injury and provided insights into the mode of anti-allodynia action. PAF antagonists, TCV-309, BN 50739 and WEB 2086 by intravenous (i.v.) and oral administration have potent and long-lasting anti-allodynia action in mice neuropathic pain models. Treatment with PAF antagonists before surgery delayed the initiation of allodynia until the effects of these treatments were abolished. Intrathecal (i.t.) injection of the PAF antagonists and siRNA against PAF receptor ameliorated allodynia. I.t. injection of the glycine receptor (GlyR)α3 siRNA reduced the anti-allodynia effect of PAF antagonists. This evidence suggests that the anti-allodynia effect of PAF antagonists is at least in part mediated by spinal relief of PAF-induced dysfunction of GlyRα3. An analysis of the mode of anti-allodynia action of TCV-309 in vivo revealed a competitive action against PAF shortly after the injection of TCV-309, converting to a non-competitive action later. The present results revealed the effectiveness in anti-allodynia of PAF antagonists in different nerve injury models, and the unique mode of action; long-lasting anti-allodynia effects mediated by spinal GlyRα3 with a competitive manner at the initial stage and the following non-competitive manner of inhibition. © 2013 European Federation of International Association for the Study of Pain Chapters.

  3. Modeling the Creation of Actionable Knowledge within a Joint Task Force Command System (Project GNOSIS)

    Science.gov (United States)

    2006-08-01

    SYSTEM SJ SYSTEM INTERACTIONS AND INFLUENCES SOCIAL ORGANIZATIONAL SYSTEM SYSTEM I Multiple actors egaglng In comunities of Commrunitles of Interest...STINFO COPY AFRL-HE-WP-TR-2006-0156 Modeling the Creation of Actionable Knowledge within a Joint Task Force Command System (Project GNOSIS) Dennis K...Cognitive Systems Branch WPAFB OH 45433-7604 Best Available Copy 20070129146 NOTICE Using Government drawings, specifications, or other data included in

  4. MOST: Modeling of SpaceWire & SpaceFibre Traffic- Applications and Operations: On-Board Segment

    Science.gov (United States)

    Dellandrea, Brice; Gouin, Baptiste; Parkes, Steve; Jameux, David

    2014-08-01

    MOST(Modeling of SpaceWire Traffic) is a representative and powerful SpaceWire traffic simulator designed to support conception, development and validation of SpaceWire networks. MOST is developed by Thales Alenia Space France (TAS-F) for the European Space Agency (ESA) and for the benefits of the SpaceWire communityThis tool was already presented in DASIA 2011 [6] and DASIA 2012 [7] as Thales Alenia Space was finishing its first step of development. Since then, the software has reached a TRL mature enough to start distributing MOST v2.2r2 to the SpaceWire community under ESA license. This released version will be presented in this paperMoreover, TAS-F is currently developing a major extension of the MOST library targeting the inclusion of S paceFibre [5] components under an University of Du ndee sub-contract. These new features will be also presented in this document.

  5. Mapping VIPS concepts for nursing interventions to the ISO reference terminology model for nursing actions: A collaborative Scandinavian analysis

    DEFF Research Database (Denmark)

    Ehnfors, Margareta; Angermo, Lilly Marit; Berring, Lene

    2006-01-01

    The aims of this study were to analyze the coherence between the concepts for nursing interventions in the Swedish VIPS model for nursing recording and the ISO Reference Terminology Model for Nursing Actions and to identify areas in the two models for further development. Seven Scandinavian experts...... analyzed the VIPS model's concepts for nursing interventions using prototypical examples of nursing actions, involving 233 units of analyses, and collaborated in mapping the two models. All nursing interventions in the VIPS model comprise actions and targets, but a few lack explicit expressions of means....... In most cases, the recipient of care is implicit. Expressions for the aim of an action are absent from the ISO model. By this mapping we identified areas for future development of the VIPS model and the experience from nursing terminology work in Scandinavia can contribute to the international...

  6. Mapping VIPS Concepts for Nursing Interventions to the ISO Reference Terminology Model for Nursing Actions: A Collaborative Scandinavian Analysis

    DEFF Research Database (Denmark)

    Lauge Berring, Lene; Ehnfors, Margareta; Angermo, Lilly

    2005-01-01

    The aims of this study were to analyze the coherence between the concepts for nursing interventions in the Swedish VIPS model for nursing recording and the ISO Reference Terminology Model for Nursing Actions and to identify areas in the two models for further development. Seven Scandinavian experts...... analyzed the VIPS model's concepts for nursing interventions using prototypical examples of nursing actions, involving 233 units of analyses, and collaborated in mapping the two models. All nursing interventions in the VIPS model comprise actions and targets, but a few lack explicit expressions of means....... In most cases, the recipient of care is implicit. Expressions for the aim of an action are absent from the ISO model. By this mapping we identified areas for future development of the VIPS model and the experience from nursing terminology work in Scandinavia can contribute to the international...

  7. Incorporating institutions and collective action into a sociohydrological model of flood resilience

    Science.gov (United States)

    Yu, David J.; Sangwan, Nikhil; Sung, Kyungmin; Chen, Xi; Merwade, Venkatesh

    2017-02-01

    Stylized sociohydrological models have mainly used social memory aspects such as community awareness or sensitivity to connect hydrologic change and social response. However, social memory alone does not satisfactorily capture the details of how human behavior is translated into collective action for water resources governance. Nor is it the only social mechanism by which the two-way feedbacks of sociohydrology can be operationalized. This study contributes toward bridging of this gap by developing a sociohydrological model of a flood resilience that includes two additional components: (1) institutions for collective action, and (2) connections to an external economic system. Motivated by the case of community-managed flood protection systems (polders) in coastal Bangladesh, we use the model to understand critical general features that affect long-term resilience of human-flood systems. Our findings suggest that occasional adversity can enhance long-term resilience. Allowing some hydrological variability to enter into the polder can increase its adaptive capacity for resilience through the preservation of social norm for collective action. Further, there are potential trade-offs associated with optimization of flood resistance through structural measures. By reducing sensitivity to floods, the system may become more fragile under the double impact of floods and economic change.

  8. The grounding of higher order concepts in action and language: a cognitive robotics model.

    Science.gov (United States)

    Stramandinoli, Francesca; Marocco, Davide; Cangelosi, Angelo

    2012-08-01

    In this paper we present a neuro-robotic model that uses artificial neural networks for investigating the relations between the development of symbol manipulation capabilities and of sensorimotor knowledge in the humanoid robot iCub. We describe a cognitive robotics model in which the linguistic input provided by the experimenter guides the autonomous organization of the robot's knowledge. In this model, sequences of linguistic inputs lead to the development of higher-order concepts grounded on basic concepts and actions. In particular, we show that higher-order symbolic representations can be indirectly grounded in action primitives directly grounded in sensorimotor experiences. The use of recurrent neural network also permits the learning of higher-order concepts based on temporal sequences of action primitives. Hence, the meaning of a higher-order concept is obtained through the combination of basic sensorimotor knowledge. We argue that such a hierarchical organization of concepts can be a possible account for the acquisition of abstract words in cognitive robots. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Facilitating cooperation in interprofessional education using a study activity model- An action research project’

    DEFF Research Database (Denmark)

    Hansen, Bodil Winther; Hatt, Camusa

    Title: Facilitating cooperation in interprofessional education using a study activity model- An action research project . Background Metropolitan University College has over the years developed interprofessional courses for students from 12 different professions, and since 2013 worked with a nati......Title: Facilitating cooperation in interprofessional education using a study activity model- An action research project . Background Metropolitan University College has over the years developed interprofessional courses for students from 12 different professions, and since 2013 worked...... in interprofessional courses and if the model has a potential as mean of pedagogical development and collaboration. Methods The study is based on action research and is a mixed method study. In 2016 the project will gather data in cooperation with lecturers through qualitative methods and a followup on the baseline......, Metropolitan University College and Roskilde University Centre. Bodil Winther Hansen (bwha@phmetropol.dk) Associate Professor, Metropolitan University College, 1999- Occupational Therapist , 1987, Art therapist 2001, Master in Adult Education and Human Resource, from Roskilde University, Denmark, 2003 Years...

  10. Understanding the cellular mode of action of vernakalant using a computational model: answers and new questions

    Directory of Open Access Journals (Sweden)

    Loewe Axel

    2015-09-01

    Full Text Available Vernakalant is a new antiarrhythmic agent for the treatment of atrial fibrillation. While it has proven to be effective in a large share of patients in clinical studies, its underlying mode of action is not fully understood. In this work, we aim to link experimental data from the subcellular, tissue, and system level using an in-silico approach. A Hill’s equation-based drug model was extended to cover the frequency dependence of sodium channel block. Two model variants were investigated: M1 based on subcellular data and M2 based on tissue level data. 6 action potential (AP markers were evaluated regarding their dose, frequency and substrate dependence. M1 comprising potassium, sodium, and calcium channel block reproduced the reported prolongation of the refractory period. M2 not including the effects on potassium channels reproduced reported AP morphology changes on the other hand. The experimentally observed increase of ERP accompanied by a shortening of APD90 was not reproduced. Thus, explanations for the drug-induced changes are provided while none of the models can explain the effects in their entirety. These results foster the understanding of vernakalant’s cellular mode of action and point out relevant gaps in our current knowledge to be addressed in future in-silico and experimental research on this aspiring antiarrhythmic agent.

  11. Integrated Modeling for the Next Generation Space Telescope "Yardstick" Concept

    Science.gov (United States)

    Mosier, Gary E.; Broduer, Steve (Technical Monitor)

    2001-01-01

    The so-called NASA "Yardstick" design concept for the Next Generation Space Telescope presents unique challenges for systems-level analysis. Simulations that integrate controls, optics, thermal, and structural models are required to evaluate baseline performance, study design sensitivities, and perform design optimization. An integrated modeling approach was chosen using a combination of commercial off-the-shelf and "in-house" developed codes. The resulting capability provides a foundation for linear and non-linear analysis, using both the time and frequency-domain methods. It readily allows various combinations of design parameters and environmental loads to be evaluated directly in terms of key science-related metrics, in this case the scalar RMS (root mean square) line-of-sight and RMS wavefront errors. This presentation first addresses the development of the component, or discipline, models for the Yardstick design. It will then proceed to present the integration of the component models, using linear-systems approaches, in order to support two of the most critical baseline performance analyses: jitter and thermal-elastic stability of the optical telescope assembly (OTA). The results of the jitter analysis indicate that disturbances from the reaction wheels coupled with the lightly-damped and highly-flexible structure present significant challenges to the baseline line-of-sight control architecture. Vibration isolation will be required to meet jitter error requirements. The results of the thermal-elastic analysis indicate that the mirror segment displacements due to ground-to-orbit cool-down of the telescope are within the expected capture range of the segment rigid-body control actuators. This means we will be able to align and phase the primary mirror. However, the results for the analysis of the thermal transient response following an attitude maneuver (slew) show that this telescope design is not sufficiently stable, passively, to meet the wavefront error

  12. The Joint Space-Time Statistics Of Macroweather Precipitation, Space-Time Statistical Factorization And Macroweather Models

    Science.gov (United States)

    Lovejoy, S.; de Lima, I. P.

    2015-12-01

    Over the range of time scales from about 10 days to 30-100 years, in addition to the familiar weather and climate regimes, there is an intermediate "macroweather" regime characterized by negative temporal fluctuation exponents: implying that fluctuations tend to cancel each other out, that averages tend to converge. We show theoretically and numerically that macroweather precipitation can be modeled by a stochastic weather-climate model (the Climate Extended Fractionally Integrated Flux, model, CEFIF) first proposed for macroweather temperatures and we show numerically that a four parameter space-time CEFIF model can approximately reproduce eight or so empirical space-time exponents. In spite of this success, CEFIF is theoretically and numerically difficult to manage. We therefore propose a simplified stochastic model in which the temporal behavior is modeled as a fractional Gaussian noise but the spatial behaviour as a multifractal (climate) cascade: a spatial extension of the recently introduced ScaLIng Macroweather Model, SLIMM. Both the CEFIF and this spatial SLIMM model have a property often implicitly assumed by climatologists: that climate statistics can be "homogenized" by normalizing them with the standard deviation of the anomalies. Physically, it means that the spatial macroweather variability corresponds to different climate zones that multiplicatively modulate the local, temporal statistics. This simplified macroweather model provides a framework for macroweather forecasting that exploits the system's long range memory and spatial correlations. We test factorization and the model with the help of three centennial, global scale precipitation products that we analyze jointly in space-time.

  13. Imbalanced Insulin Actions in Obesity and Type 2 Diabetes: Key Mouse Models of Insulin Signaling Pathway.

    Science.gov (United States)

    Kubota, Tetsuya; Kubota, Naoto; Kadowaki, Takashi

    2017-04-04

    Since the discovery of the tyrosine kinase activity of the insulin receptor (IR), researchers have been engaged in intensive efforts to resolve physiological functions of IR and its major downstream targets, insulin receptor substrate 1 (Irs1) and Irs2. Studies conducted using systemic and tissue-specific gene-knockout mice of IR, Irs1, and Irs2 have revealed the physiological roles of these molecules in each tissue and interactions among multiple tissues. In obesity and type 2 diabetes, selective downregulation of Irs2 and its downstream actions to cause reduced insulin actions was associated with increased insulin actions through Irs1 in variety tissues. Thus, we propose the novel concept of "organ- and pathway-specific imbalanced insulin action" in obesity and type 2 diabetes, which includes and extends "selective insulin resistance." This Review focuses on recent progress in understanding insulin signaling and insulin resistance using key mouse models for elucidating pathophysiology of human obesity and type 2 diabetes. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Fitting identity in the reasoned action framework: A meta-analysis and model comparison.

    Science.gov (United States)

    Paquin, Ryan S; Keating, David M

    2017-01-01

    Several competing models have been put forth regarding the role of identity in the reasoned action framework. The standard model proposes that identity is a background variable. Under a typical augmented model, identity is treated as an additional direct predictor of intention and behavior. Alternatively, it has been proposed that identity measures are inadvertent indicators of an underlying intention factor (e.g., a manifest-intention model). In order to test these competing hypotheses, we used data from 73 independent studies (total N = 23,917) to conduct a series of meta-analytic structural equation models. We also tested for moderation effects based on whether there was a match between identity constructs and the target behaviors examined (e.g., if the study examined a "smoker identity" and "smoking behavior," there would be a match; if the study examined a "health conscious identity" and "smoking behavior," there would not be a match). Average effects among primary reasoned action variables were all substantial, rs = .37-.69. Results gave evidence for the manifest-intention model over the other explanations, and a moderation effect by identity-behavior matching.

  15. A coarse-grained model for synergistic action of multiple enzymes on cellulose

    Directory of Open Access Journals (Sweden)

    Asztalos Andrea

    2012-08-01

    Full Text Available Abstract Background Degradation of cellulose to glucose requires the cooperative action of three classes of enzymes, collectively known as cellulases. Endoglucanases randomly bind to cellulose surfaces and generate new chain ends by hydrolyzing β-1,4-D-glycosidic bonds. Exoglucanases bind to free chain ends and hydrolyze glycosidic bonds in a processive manner releasing cellobiose units. Then, β-glucosidases hydrolyze soluble cellobiose to glucose. Optimal synergistic action of these enzymes is essential for efficient digestion of cellulose. Experiments show that as hydrolysis proceeds and the cellulose substrate becomes more heterogeneous, the overall degradation slows down. As catalysis occurs on the surface of crystalline cellulose, several factors affect the overall hydrolysis. Therefore, spatial models of cellulose degradation must capture effects such as enzyme crowding and surface heterogeneity, which have been shown to lead to a reduction in hydrolysis rates. Results We present a coarse-grained stochastic model for capturing the key events associated with the enzymatic degradation of cellulose at the mesoscopic level. This functional model accounts for the mobility and action of a single cellulase enzyme as well as the synergy of multiple endo- and exo-cellulases on a cellulose surface. The quantitative description of cellulose degradation is calculated on a spatial model by including free and bound states of both endo- and exo-cellulases with explicit reactive surface terms (e.g., hydrogen bond breaking, covalent bond cleavages and corresponding reaction rates. The dynamical evolution of the system is simulated by including physical interactions between cellulases and cellulose. Conclusions Our coarse-grained model reproduces the qualitative behavior of endoglucanases and exoglucanases by accounting for the spatial heterogeneity of the cellulose surface as well as other spatial factors such as enzyme crowding. Importantly, it captures

  16. Caenorhabditis elegans - A model system for space biology studies

    Science.gov (United States)

    Johnson, Thomas E.; Nelson, Gregory A.

    1991-01-01

    The utility of the nematode Caenorhabditis elegans in studies spanning aspects of development, aging, and radiobiology is reviewed. These topics are interrelated via cellular and DNA repair processes especially in the context of oxidative stress and free-radical metabolism. The relevance of these research topics to problems in space biology is discussed and properties of the space environment are outlined. Exposure to the space-flight environment can induce rapid changes in living systems that are similar to changes occurring during aging; manipulation of these environmental parameters may represent an experimental strategy for studies of development and senescence. The current and future opportunities for such space-flight experimentation are presented.

  17. Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models.

    Science.gov (United States)

    Danhof, Meindert

    2015-10-01

    Gerhard Levy started his investigations on the "Kinetics of Drug Action in Disease States" in the fall of 1980. The objective of his research was to study inter-individual variation in pharmacodynamics. To this end, theoretical concepts and experimental approaches were introduced, which enabled assessment of the changes in pharmacodynamics per se, while excluding or accounting for the cofounding effects of concomitant changes in pharmacokinetics. These concepts were applied in several studies. The results, which were published in 45 papers in the years 1984-1994, showed considerable variation in pharmacodynamics. These initial studies on kinetics of drug action in disease states triggered further experimental research on the relations between pharmacokinetics and pharmacodynamics. Together with the concepts in Levy's earlier publications "Kinetics of Pharmacologic Effects" (Clin Pharmacol Ther 7(3): 362-372, 1966) and "Kinetics of pharmacologic effects in man: the anticoagulant action of warfarin" (Clin Pharmacol Ther 10(1): 22-35, 1969), they form a significant impulse to the development of physiology-based pharmacodynamic (PBPD) modeling as novel discipline in the pharmaceutical sciences. This paper reviews Levy's research on the "Kinetics of Drug Action in Disease States". Next it addresses the significance of his research for the evolution of PBPD modeling as a scientific discipline. PBPD models contain specific expressions to characterize in a strictly quantitative manner processes on the causal path between exposure (in terms of concentration at the target site) and the drug effect (in terms of the change in biological function). Pertinent processes on the causal path are: (1) target site distribution, (2) target binding and activation and (3) transduction and homeostatic feedback.

  18. A model for emergence of space and time

    Directory of Open Access Journals (Sweden)

    J. Ambjørn

    2015-10-01

    Full Text Available We study string field theory (third quantization of the two-dimensional model of quantum geometry called generalized CDT (“causal dynamical triangulations”. Like in standard non-critical string theory the so-called string field Hamiltonian of generalized CDT can be associated with W-algebra generators through the string mode expansion. This allows us to define an “absolute” vacuum. “Physical” vacua appear as coherent states created by vertex operators acting on the absolute vacuum. Each coherent state corresponds to specific values of the coupling constants of generalized CDT. The cosmological “time” only exists relatively to a given “physical” vacuum and comes into existence before space, which is created because the “physical” vacuum is unstable. Thus each CDT “universe” is created as a “Big Bang” from the absolute vacuum, its time evolution is governed by the CDT string field Hamiltonian with given coupling constants, and one can imagine interactions between CDT universes with different coupling constants (“fourth quantization”

  19. A model for emergence of space and time

    Energy Technology Data Exchange (ETDEWEB)

    Ambjørn, J., E-mail: ambjorn@nbi.dk [The Niels Bohr Institute, Copenhagen University, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark); Institute for Mathematics, Astrophysics and Particle Physics (IMAPP), Radbaud University Nijmegen, Heyendaalseweg 135, 6525 AJ, Nijmegen (Netherlands); Watabiki, Y., E-mail: watabiki@th.phys.titech.ac.jp [Tokyo Institute of Technology, Dept. of Physics, High Energy Theory Group, 2-12-1 Oh-okayama, Meguro-ku, Tokyo 152-8551 (Japan)

    2015-10-07

    We study string field theory (third quantization) of the two-dimensional model of quantum geometry called generalized CDT (“causal dynamical triangulations”). Like in standard non-critical string theory the so-called string field Hamiltonian of generalized CDT can be associated with W-algebra generators through the string mode expansion. This allows us to define an “absolute” vacuum. “Physical” vacua appear as coherent states created by vertex operators acting on the absolute vacuum. Each coherent state corresponds to specific values of the coupling constants of generalized CDT. The cosmological “time” only exists relatively to a given “physical” vacuum and comes into existence before space, which is created because the “physical” vacuum is unstable. Thus each CDT “universe” is created as a “Big Bang” from the absolute vacuum, its time evolution is governed by the CDT string field Hamiltonian with given coupling constants, and one can imagine interactions between CDT universes with different coupling constants (“fourth quantization”)

  20. Optimizing phonon space in the phonon-coupling model

    Science.gov (United States)

    Tselyaev, V.; Lyutorovich, N.; Speth, J.; Reinhard, P.-G.

    2017-08-01

    We present a new scheme to select the most relevant phonons in the phonon-coupling model, named here the time-blocking approximation (TBA). The new criterion, based on the phonon-nucleon coupling strengths rather than on B (E L ) values, is more selective and thus produces much smaller phonon spaces in the TBA. This is beneficial in two respects: first, it curbs the computational cost, and second, it reduces the danger of double counting in the expansion basis of the TBA. We use here the TBA in a form where the coupling strength is regularized to keep the given Hartree-Fock ground state stable. The scheme is implemented in a random-phase approximation and TBA code based on the Skyrme energy functional. We first explore carefully the cutoff dependence with the new criterion and can work out a natural (optimal) cutoff parameter. Then we use the freshly developed and tested scheme for a survey of giant resonances and low-lying collective states in six doubly magic nuclei looking also at the dependence of the results when varying the Skyrme parametrization.

  1. The Production and the Uneven Valorization of Urban Space in Campos Dos Goytacazes-RJ: An Analysis of State and Real Estate Developers Actions

    Directory of Open Access Journals (Sweden)

    Marcos Antônio Silvestre Gomes

    2015-07-01

    Full Text Available This article discusses some aspects of the production of urban space considering the social agents actions. The methodology was based on literature searches, data surveys and interviews in public and private agencies, empirical observations and mapping of the urban area. The methodology was based on literature searches, data surveys and interviews in public and private agencies, empirical observations and mapping of the urban area. The objective is to present an analysis of state and real estate developers actions in the production and uneven valorization of urban space in Campos dos Goytacazes-RJ. The results of work indicate the intensification and complexification of actions of these agents with the advent of the oil economy. In the period 1981-2011 there was an intense valuation of South West-East axis of the city, with a vertiginous process of vertical integration and deployment of a high standard closed allotments, which has contributed to a significant increase in land prices in specific parts of city. There was also a bigger increase in the land's prices in areas considered of greater real estate interest.

  2. Spaces

    Directory of Open Access Journals (Sweden)

    Maziar Nekovee

    2010-01-01

    Full Text Available Cognitive radio is being intensively researched as the enabling technology for license-exempt access to the so-called TV White Spaces (TVWS, large portions of spectrum in the UHF/VHF bands which become available on a geographical basis after digital switchover. Both in the US, and more recently, in the UK the regulators have given conditional endorsement to this new mode of access. This paper reviews the state-of-the-art in technology, regulation, and standardisation of cognitive access to TVWS. It examines the spectrum opportunity and commercial use cases associated with this form of secondary access.

  3. Mass Action Models Describing Extant Horizontal Transfer of Plasmids: Inferences and Parameter Sensitivities

    DEFF Research Database (Denmark)

    Smets, Barth F.; Lardon, Laurent

    2009-01-01

    Predicting the fate of horizontally transmissible elements in extant microbial communities might be facilitated by the availability of suitable mathematical models. Since the mid-1970s, mass action models have been introduced to describe the transfer of conjugal and mobilizable genetic elements...... of the outcomes to the various plasmid dynamic parameters. For our analysis, we developed a set of user-friendly MatLab® routines, which are deposited in the public domain. We hope that the availability of these routines will encourage the computationally untrained microbiologist to make use of these mathematical...

  4. A model for a regional transportation system within the geostationary space complex

    Science.gov (United States)

    Koelle, H. H.

    The geostationary orbit about the Earth is presently used by a great number of communication and observation satellites. These nearly one hundred satellites have a limited lifetime and are expected to be replaced in due time by unmanned platforms of increasing size. Maintenance, repair and removal of these platforms by unmanned and manned space vehicles is one of the options discussed with increasing frequency. Another space system envisioned for the geostationary orbit are space solar power plants (SSPS). They have been investigated during the last two decades to find out whether there are any technical or financial problems which have to be overcome before a SSPS can materialize sometime in the next century. So far, none have been discovered, but proof is lacking that a SSPS is technically feasible and competitive if compared with other options to solve the energy problem on this planet in the next century. A partial problem for the acquisition and operation of a system of space power satellites is their assembly, maintenance and repair. Most of it must be done automatically but a sizable crew would probably have to be in GEO for quick action. Such a crew requires not only habitats, storages and a local energy supply, but also a regional space transportation system to transport spares, tools and people between the individual power plants and the other elements of the geostationary infrastructure. Such a regional transportation system for local transportation in the geostationary orbit (GRET) was recently studied at the Aerospace Institute of the Technical University of Berlin. It envisions a fleet of small space vehicles for interorbital transfer requiring modest velocity changes and flight times. The fleet comprises taxis for passenger transport, tugs for cargo transport and several unmanned and manned services vehicles of different sizes. These vehicles are housed in a special GEO space facility connected directly to the GEO spaceport. A SSPS driven market

  5. Motion Primitives and Probabilistic Edit Distance for Action Recognition

    DEFF Research Database (Denmark)

    Fihl, Preben; Holte, Michael Boelstoft; Moeslund, Thomas B.

    2009-01-01

    The number of potential applications has made automatic recognition of human actions a very active research area. Different approaches have been followed based on trajectories through some state space. In this paper we also model an action as a trajectory through a state space, but we represent t...

  6. Impact evaluation ofwelfare actions over a community in Colombia, using a data correlated model

    Directory of Open Access Journals (Sweden)

    Juan C. Salazar U

    2010-04-01

    Full Text Available The impact evaluation of a communitarian program sometimes is based on statistical techniques such as linear regression models analysis when the goal is usually to quantify its effects on both social and welfare characteristics of a community. This involves the study of mental health and social variables which effects could not be easily quantified due to the presence of correlation structures among the observations within a particular subject. For this reason it is advisable to use linear mixed models to this kind of study. Objective: To calculate the impact of the effects produced by actions of the Instituto de Deportes y Recreación de Medellín (i n d e r on the participant population. Methodology: from a sample collected by i n d e r back in 2007, about participants and no participants of its programs, generalized linear models were estimated to explain the behavior of both social and psychological variables. Then, by using a logistic regression model a matching procedure was performed to identify the subjects and their repeated measures that will serve as inputs to measure the impact of the intervention of the welfare activities on the community by means of a linear mixed model. Results: The linear mixed estimation process identified important interaction variables that favor the intervention welfare actions. Conclusions:from the participation in the i n d e r activities, an improvement of variables related with social capital was found.

  7. Neuronal chains for actions in the parietal lobe: a computational model.

    Directory of Open Access Journals (Sweden)

    Fabian Chersi

    Full Text Available The inferior part of the parietal lobe (IPL is known to play a very important role in sensorimotor integration. Neurons in this region code goal-related motor acts performed with the mouth, with the hand and with the arm. It has been demonstrated that most IPL motor neurons coding a specific motor act (e.g., grasping show markedly different activation patterns according to the final goal of the action sequence in which the act is embedded (grasping for eating or grasping for placing. Some of these neurons (parietal mirror neurons show a similar selectivity also during the observation of the same action sequences when executed by others. Thus, it appears that the neuronal response occurring during the execution and the observation of a specific grasping act codes not only the executed motor act, but also the agent's final goal (intention.In this work we present a biologically inspired neural network architecture that models mechanisms of motor sequences execution and recognition. In this network, pools composed of motor and mirror neurons that encode motor acts of a sequence are arranged in form of action goal-specific neuronal chains. The execution and the recognition of actions is achieved through the propagation of activity bursts along specific chains modulated by visual and somatosensory inputs.The implemented spiking neuron network is able to reproduce the results found in neurophysiological recordings of parietal neurons during task performance and provides a biologically plausible implementation of the action selection and recognition process.Finally, the present paper proposes a mechanism for the formation of new neural chains by linking together in a sequential manner neurons that represent subsequent motor acts, thus producing goal-directed sequences.

  8. Tending to Change: Toward a Situated Model of Affinity Spaces

    Science.gov (United States)

    Bommarito, Dan

    2014-01-01

    The concept of affinity spaces, a theoretical construct used to analyze literate activity from a spatial perspective, has gained popularity among scholars of literacy studies and, particularly, video-game studies. This article seeks to expand current notions of affinity spaces by identifying key assumptions that have limited researchers'…

  9. From molecular signatures to predictive biomarkers: Modeling disease pathophysiology and drug mechanism of action

    Directory of Open Access Journals (Sweden)

    Andreas eHeinzel

    2014-08-01

    Full Text Available Omics profiling significantly expanded the molecular landscape describing clinical phenotypes. Association analysis resulted in first diagnostic and prognostic biomarker signatures entering clinical utility. However, utilizing Omics for deepening our understanding of disease pathophysiology, and further including specific interference with drug mechanism of action on a molecular process level still sees limited added value in the clinical setting.We exemplify a computational workflow for expanding from statistics-based association analysis towards deriving molecular pathway and process models for characterizing phenotypes and drug mechanism of action. Interference analysis on the molecular model level allows identification of predictive biomarker candidates for testing drug response. We discuss this strategy on diabetic nephropathy, a complex clinical phenotype triggered by diabetes and presenting with renal as well as cardiovascular endpoints. A molecular pathway map indicates involvement of multiple molecular mechanisms, and selected biomarker candidates reported as associated with disease progression are identified for specific molecular processes. Selective interference of drug mechanism of action and disease-associated processes is identified for drug classes in clinical use, in turn providing precision medicine hypotheses utilizing predictive biomarkers.

  10. Software cost/resource modeling: Deep space network software cost estimation model

    Science.gov (United States)

    Tausworthe, R. J.

    1980-01-01

    A parametric software cost estimation model prepared for JPL deep space network (DSN) data systems implementation tasks is presented. The resource estimation model incorporates principles and data from a number of existing models, such as those of the General Research Corporation, Doty Associates, IBM (Walston-Felix), Rome Air Force Development Center, University of Maryland, and Rayleigh-Norden-Putnam. The model calibrates task magnitude and difficulty, development environment, and software technology effects through prompted responses to a set of approximately 50 questions. Parameters in the model are adjusted to fit JPL software lifecycle statistics. The estimation model output scales a standard DSN work breakdown structure skeleton, which is then input to a PERT/CPM system, producing a detailed schedule and resource budget for the project being planned.

  11. Geometry of s-space and its using for modeling and optimization complex systems

    Directory of Open Access Journals (Sweden)

    Y. N. Kovaluov

    2003-06-01

    Full Text Available Components of the S-space wave model - axioms, self-organization theory, mappings - are described.The general model “human-environment” and some of the working models are considered. Also contains examples of application of the S-space self-organization theory by optimization of complex technological systems

  12. Theories of reasoned action and planned behavior as models of condom use: a meta-analysis.

    Science.gov (United States)

    Albarracín, D; Johnson, B T; Fishbein, M; Muellerleile, P A

    2001-01-01

    To examine how well the theories of reasoned action and planned behavior predict condom use, the authors synthesized 96 data sets (N = 22,594) containing associations between the models' key variables. Consistent with the theory of reasoned action's predictions, (a) condom use was related to intentions (weighted mean r. = .45), (b) intentions were based on attitudes (r. = .58) and subjective norms (r. = .39), and (c) attitudes were associated with behavioral beliefs (r. = .56) and norms were associated with normative beliefs (r. = .46). Consistent with the theory of planned behavior's predictions, perceived behavioral control was related to condom use intentions (r. = .45) and condom use (r. = .25), but in contrast to the theory, it did not contribute significantly to condom use. The strength of these associations, however, was influenced by the consideration of past behavior. Implications of these results for HIV prevention efforts are discussed.

  13. Suicide prevention by online support groups: an action theory-based model of emotional first aid.

    Science.gov (United States)

    Gilat, Itzhak; Shahar, Golan

    2009-01-01

    In the last two decades, online support groups have become a valuable source of help for individuals in suicidal crisis. Their attractiveness is attributed to features that enhance help-seeking and self-disclosure such as availability, anonymity, and use of written communication. However, online support groups also suffer from limitations and potential risks as agents of suicide prevention. The Israeli Association for Emotional First Aid (ERAN) has developed a practical model that seeks to maximize the benefits and minimize the risks of online suicide prevention. The model applies the Action Theory concepts whereby individuals shape their own environment. The present paper presents the model, which is based on an online support group combined with personal chat and a telephonic help line. The online support group is moderated by paraprofessionals who function as both process regulators and support providers. The principles and practice of the model are described, the theoretical rationale is presented, and directions for future research are suggested.

  14. Scalability of the muscular action in a parametric 3D model of the index finger.

    Science.gov (United States)

    Sancho-Bru, Joaquín L; Vergara, Margarita; Rodríguez-Cervantes, Pablo-Jesús; Giurintano, David J; Pérez-González, Antonio

    2008-01-01

    A method for scaling the muscle action is proposed and used to achieve a 3D inverse dynamic model of the human finger with all its components scalable. This method is based on scaling the physiological cross-sectional area (PCSA) in a Hill muscle model. Different anthropometric parameters and maximal grip force data have been measured and their correlations have been analyzed and used for scaling the PCSA of each muscle. A linear relationship between the normalized PCSA and the product of the length and breadth of the hand has been finally used for scaling, with a slope of 0.01315 cm(-2), with the length and breadth of the hand expressed in centimeters. The parametric muscle model has been included in a parametric finger model previously developed by the authors, and it has been validated reproducing the results of an experiment in which subjects from different population groups exerted maximal voluntary forces with their index finger in a controlled posture.

  15. Using Latent Class Modeling to Detect Bimodality in Spacing Effect Data

    Science.gov (United States)

    Verkoeijen, Peter P. J. L.; Bouwmeester, Samantha

    2008-01-01

    A recently proposed theory of the spacing effect [Raaijmakers, J. G. W. (2003). Spacing and repetition effects in human memory: application of the SAM model. "Cognitive Science," 27, 431-452.] suggests that the spacing effect is conditional on study-phase retrieval leading to two groups of students showing different magnitudes of the spacing…

  16. Machine learning-based models to predict modes of toxic action of phenols to Tetrahymena pyriformis.

    Science.gov (United States)

    Castillo-Garit, J A; Casañola-Martin, G M; Barigye, S J; Pham-The, H; Torrens, F; Torreblanca, A

    2017-09-01

    The phenols are structurally heterogeneous pollutants and they present a variety of modes of toxic action (MOA), including polar narcotics, weak acid respiratory uncouplers, pro-electrophiles, and soft electrophiles. Because it is often difficult to determine correctly the mechanism of action of a compound, quantitative structure-activity relationship (QSAR) methods, which have proved their interest in toxicity prediction, can be used. In this work, several QSAR models for the prediction of MOA of 221 phenols to the ciliated protozoan Tetrahymena pyriformis, using Chemistry Development Kit descriptors, are reported. Four machine learning techniques (ML), k-nearest neighbours, support vector machine, classification trees, and artificial neural networks, have been used to develop several models with higher accuracies and predictive capabilities for distinguishing between four MOAs. They showed global accuracy values between 95.9% and 97.7% and area under Receiver Operator Curve values between 0.978 and 0.998; additionally, false alarm rate values were below 8.2% for training set. In order to validate our models, cross-validation (10-folds-out) and external test-set were performed with good behaviour in all cases. These models, obtained with ML techniques, were compared with others previously reported by other researchers, and the improvement was significant.

  17. Anticlockwise or clockwise? A dynamic Perception-Action-Laterality model for directionality bias in visuospatial functioning.

    Science.gov (United States)

    Karim, A K M Rezaul; Proulx, Michael J; Likova, Lora T

    2016-09-01

    Orientation bias and directionality bias are two fundamental functional characteristics of the visual system. Reviewing the relevant literature in visual psychophysics and visual neuroscience we propose here a three-stage model of directionality bias in visuospatial functioning. We call this model the 'Perception-Action-Laterality' (PAL) hypothesis. We analyzed the research findings for a wide range of visuospatial tasks, showing that there are two major directionality trends in perceptual preference: clockwise versus anticlockwise. It appears these preferences are combinatorial, such that a majority of people fall in the first category demonstrating a preference for stimuli/objects arranged from left-to-right rather than from right-to-left, while people in the second category show an opposite trend. These perceptual biases can guide sensorimotor integration and action, creating two corresponding turner groups in the population. In support of PAL, we propose another model explaining the origins of the biases - how the neurogenetic factors and the cultural factors interact in a biased competition framework to determine the direction and extent of biases. This dynamic model can explain not only the two major categories of biases in terms of direction and strength, but also the unbiased, unreliably biased or mildly biased cases in visuosptial functioning. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. Worldline Path-Integral Representations for Standard Model Propagators and Effective Actions

    Directory of Open Access Journals (Sweden)

    Somdatta Bhattacharya

    2017-01-01

    Full Text Available We develop the formalism to do worldline calculations relevant for the Standard Model. For that, we first figure out the worldline representations for the free propagators of massless chiral fermions of a single generation and gauge bosons of the Standard Model. Then we extend the formalism to the massive and dressed cases for the fermions and compute the QED vertex. We then go over fermionic one-loop effective actions and anomalies. To our knowledge, in the places where there has been an attempt at deriving the gauge boson propagator, the derivation is somewhat contrived, and we believe our derivation is more straightforward. Moreover, our incorporation of internal degrees of freedom is novel and sports some new features. The derivation of the QED vertex is also new. The treatment of the fermionic one-loop effective actions leads to a particularly economical derivation of chiral anomalies and the gauge anomaly freedom in the Standard Model, improving upon the state of the art in the literature. The appropriate worldline formalism developed thus sets the stage for Standard Model calculations beyond the tree and one-loop cases that incorporate Bern-Kosower type formulae for multiloop amplitudes, relevant for processes at the LHC.

  19. Using Model Based Systems Engineering and the Systems Modeling Language to Develop Space Mission Area Architectures

    Science.gov (United States)

    2013-09-01

    DoDAF Department of Defense Architecture Framework DSP Defense Support Program FFRDC Federally Funded Research and Development Center GEO...mission area, legacy systems such as the Defense Space Program ( DSP ) and other Intelligence Community sensors each have unique system level...domain-specific languages such as UML for software design and VHDL and three-dimensional geometric modeling for hardware design. SysML is intended to

  20. Space-Wise approach for airborne gravity data modelling

    Science.gov (United States)

    Sampietro, D.; Capponi, M.; Mansi, A. H.; Gatti, A.; Marchetti, P.; Sansò, F.

    2017-05-01

    Regional gravity field modelling by means of remove-compute-restore procedure is nowadays widely applied in different contexts: it is the most used technique for regional gravimetric geoid determination, and it is also used in exploration geophysics to predict grids of gravity anomalies (Bouguer, free-air, isostatic, etc.), which are useful to understand and map geological structures in a specific region. Considering this last application, due to the required accuracy and resolution, airborne gravity observations are usually adopted. However, due to the relatively high acquisition velocity, presence of atmospheric turbulence, aircraft vibration, instrumental drift, etc., airborne data are usually contaminated by a very high observation error. For this reason, a proper procedure to filter the raw observations in both the low and high frequencies should be applied to recover valuable information. In this work, a software to filter and grid raw airborne observations is presented: the proposed solution consists in a combination of an along-track Wiener filter and a classical Least Squares Collocation technique. Basically, the proposed procedure is an adaptation to airborne gravimetry of the Space-Wise approach, developed by Politecnico di Milano to process data coming from the ESA satellite mission GOCE. Among the main differences with respect to the satellite application of this approach, there is the fact that, while in processing GOCE data the stochastic characteristics of the observation error can be considered a-priori well known, in airborne gravimetry, due to the complex environment in which the observations are acquired, these characteristics are unknown and should be retrieved from the dataset itself. The presented solution is suited for airborne data analysis in order to be able to quickly filter and grid gravity observations in an easy way. Some innovative theoretical aspects focusing in particular on the theoretical covariance modelling are presented too

  1. A Bayesian network model for predicting aquatic toxicity mode of action using two dimensional theoretical molecular descriptors-abstract

    Science.gov (United States)

    The mode of toxic action (MoA) has been recognized as a key determinant of chemical toxicity but MoA classification in aquatic toxicology has been limited. We developed a Bayesian network model to classify aquatic toxicity mode of action using a recently published dataset contain...

  2. Exploring the Model Design Space for Battery Health Management

    Data.gov (United States)

    National Aeronautics and Space Administration — Battery Health Management (BHM) is a core enabling technology for the success and widespread adoption of the emerging electric vehicles of today. Although battery...

  3. Integrated Modeling, Analysis, and Verification for Space Missions Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will further MBSE technology in fundamental ways by strengthening the link between SysML tools and framework engineering execution environments. Phoenix...

  4. Computational analysis of the human sinus node action potential: model development and effects of mutations.

    Science.gov (United States)

    Fabbri, Alan; Fantini, Matteo; Wilders, Ronald; Severi, Stefano

    2017-04-01

    We constructed a comprehensive mathematical model of the spontaneous electrical activity of a human sinoatrial node (SAN) pacemaker cell, starting from the recent Severi-DiFrancesco model of rabbit SAN cells. Our model is based on electrophysiological data from isolated human SAN pacemaker cells and closely matches the action potentials and calcium transient that were recorded experimentally. Simulated ion channelopathies explain the clinically observed changes in heart rate in corresponding mutation carriers, providing an independent qualitative validation of the model. The model shows that the modulatory role of the 'funny current' (I f ) in the pacing rate of human SAN pacemaker cells is highly similar to that of rabbit SAN cells, despite its considerably lower amplitude. The model may prove useful in the design of experiments and the development of heart-rate modulating drugs. The sinoatrial node (SAN) is the normal pacemaker of the mammalian heart.  Over several decades, a large amount of data on the ionic mechanisms underlying the spontaneous electrical activity of SAN pacemaker cells has been obtained, mostly in experiments on single cells isolated from rabbit SAN. This wealth of data has allowed the development of mathematical models of the electrical activity of rabbit SAN pacemaker cells. The present study aimed to construct a comprehensive model of the electrical activity of a human SAN pacemaker cell using recently obtained electrophysiological data from human SAN pacemaker cells.  We based our model on the recent Severi-DiFrancesco model of a rabbit SAN pacemaker cell. The action potential and calcium transient of the resulting model are close to the experimentally recorded values. The model has a much smaller 'funny current' (I f ) than do rabbit cells, although its modulatory role is highly similar. Changes in pacing rate upon the implementation of mutations associated with sinus node dysfunction agree with the clinical observations. This agreement

  5. An application of the Continuous Opinions and Discrete Actions (CODA model to adolescent smoking initiation.

    Directory of Open Access Journals (Sweden)

    Ruoyan Sun

    Full Text Available We investigated the impact of peers' opinions on the smoking initiation process among adolescents. We applied the Continuous Opinions and Discrete Actions (CODA model to study how social interactions change adolescents' opinions and behaviors about smoking. Through agent-based modeling (ABM, we simulated a population of 2500 adolescents and compared smoking prevalence to data from 9 cohorts of adolescents in the National Survey on Drug Use and Health (NSDUH from year 2001 till 2014. Our model adjusts well for NSDUH data according to pseudo R2 values, which are at least 96%. Optimal parameter values indicate that adolescents exhibit imitator characteristics with regard to smoking opinions. The imitator characteristics suggests that teenagers tend to update their opinions consistently according to what others do, and these opinions later translate into smoking behaviors. As a result, peer influence from social networks plays a big role in the smoking initiation process and should be an important driver in policy formulation.

  6. Mathematical model of an indirect action fuel flow controller for aircraft jet engines

    Science.gov (United States)

    Tudosie, Alexandru-Nicolae

    2017-06-01

    The paper deals with a fuel mass flow rate controller with indirect action for aircraft jet engines. The author has identified fuel controller's main parts and its operation mode, then, based on these observations, one has determined motion equations of each main part, which have built system's non-linear mathematical model. In order to realize a better study this model was linearised (using the finite differences method) and then adimensionalized. Based on this new form of the mathematical model, after applying Laplace transformation, the embedded system (controller+engine) was described by the block diagram with transfer functions. Some Simulink-Matlab simulations were performed, concerning system's time behavior for step input, which lead to some useful conclusions and extension possibilities.

  7. Antiulcer activity and the mechanism of action of magaldrate in gastric ulceration models of rat.

    Science.gov (United States)

    Patel, A V; Santani, D D; Goyal, R K

    2000-07-01

    The present study was undertaken to investigate the mechanism of cytoprotective effects of magaldrate in aspirin plus pylorus-ligation model and ethanol-induced gastric ulcer model in rats. Magaldrate (60 mg/kg, p.o.) produced a significant reduction in the ulcer index and significant increase in mucus content in ethanol-induced gastric ulceration in rats. In aspirin plus pylorus-ligation model magaldrate produced significant decrease in ulcer index, total acidity and protein content (PR). It did not produce any significant change in volume of gastric secretion. However, it produced significant increase in total carbohydrate (TC) level but not in ratio between TC and proteins. It also produced a significant decrease in lipid peroxidation (as expressed by thiobarbituric acid reactive substance). Our data suggests the cytoprotective action of magaldrate on gastric mucosal cells which may be due to protection of gastric mucosa from lipid peroxidation.

  8. An application of the Continuous Opinions and Discrete Actions (CODA) model to adolescent smoking initiation.

    Science.gov (United States)

    Sun, Ruoyan; Mendez, David

    2017-01-01

    We investigated the impact of peers' opinions on the smoking initiation process among adolescents. We applied the Continuous Opinions and Discrete Actions (CODA) model to study how social interactions change adolescents' opinions and behaviors about smoking. Through agent-based modeling (ABM), we simulated a population of 2500 adolescents and compared smoking prevalence to data from 9 cohorts of adolescents in the National Survey on Drug Use and Health (NSDUH) from year 2001 till 2014. Our model adjusts well for NSDUH data according to pseudo R2 values, which are at least 96%. Optimal parameter values indicate that adolescents exhibit imitator characteristics with regard to smoking opinions. The imitator characteristics suggests that teenagers tend to update their opinions consistently according to what others do, and these opinions later translate into smoking behaviors. As a result, peer influence from social networks plays a big role in the smoking initiation process and should be an important driver in policy formulation.

  9. Facilitating cooperation in interprofessional education using a study activity model- An action research project’

    DEFF Research Database (Denmark)

    Hansen, Bodil Winther; Hatt, Camusa

    2016-01-01

    Title: Facilitating cooperation in interprofessional education using a study activity model- An action research project . Background Metropolitan University College has over the years developed interprofessional courses for students from 12 different professions, and since 2013 worked...... conducted a baseline investigation in 2015, exploring 538 students´ and participating lecturers´ evaluation of the current use of the model in interprofessional courses. This baseline and previous evaluations show that there are continuous challenges, concerning both the collaboration between the course...... lecturers and student satisfaction and participation. Objectives Develop collaborative and didactical knowledge and generate deeper insight into facilitation of interprofessional education (IPE) and interprofessional collaborative practice (IPC). Investigate the current use of the study activity model...

  10. Test of a model of antiarrhythmic drug action. Effects of quinidine and lidocaine on myocardial conduction.

    Science.gov (United States)

    Hondeghem, L; Katzung, B G

    1980-06-01

    The effects of quinidine and lidocaine on the maximum upstroke velocity (Vmax) of the ventricular myocardial action potential were compared with the effects predicted by a model over a wide range of driving rates, rhythm disturbances and holding potentials. These rate-, rhythm- and voltage-dependent effects were accurately predicted by the proposed model. The model was also able to predict several previously undocumented properties of the drugs: 1) If lidocaine decreases Vmax of a pulse train, the steady state is reached within a few action potentials. 2) The poststimulation recovery of Vmax in the presence of lidocaine or quinidine can occur in a multiexponential fashion, if the membrane potential is kept at the potential where both the fast (operating mainly at more negative membrane potentials) and the slow (operating at more positive potentials) recovery processes are operative. 3) Hyperpolarization markedly attenuates the rate-dependent drug effects. 4) Combinations of lidocaine and quinidine have a superadditive effect on the Vmax of early extrasystoles.

  11. A neural model for temporal order judgments and their active recalibration: a common mechanism for space and time?

    Directory of Open Access Journals (Sweden)

    Mingbo eCai

    2012-11-01

    Full Text Available When observers experience a constant delay between their motor actions and sensory feedback, their perception of the temporal order between actions and sensations adapt (Stetson et al., 2006a. We present here a novel neural model that can explain temporal order judgments (TOJs and their recalibration. Our model employs three ubiquitous features of neural systems: 1 information pooling, 2 opponent processing, and 3 synaptic scaling. Specifically, the model proposes that different populations of neurons encode different delays between motor-sensory events, the outputs of these populations feed into rivaling neural populations (encoding before and after, and the activity difference between these populations determines the perceptual judgment. As a consequence of synaptic scaling of input weights, motor acts which are consistently followed by delayed sensory feedback will cause the network to recalibrate its point of subjective simultaneity. The structure of our model raises the possibility that recalibration of TOJs is a temporal analogue to the motion aftereffect. In other words, identical neural mechanisms may be used to make perceptual determinations about both space and time. Our model captures behavioral recalibration results for different numbers of adapting trials and different adapting delays. In line with predictions of the model, we additionally demonstrate that temporal recalibration can last through time, in analogy to storage of the motion aftereffect.

  12. Toward an integrative social identity model of collective action: a quantitative research synthesis of three socio-psychological perspectives.

    Science.gov (United States)

    van Zomeren, Martijn; Postmes, Tom; Spears, Russell

    2008-07-01

    An integrative social identity model of collective action (SIMCA) is developed that incorporates 3 socio-psychological perspectives on collective action. Three meta-analyses synthesized a total of 182 effects of perceived injustice, efficacy, and identity on collective action (corresponding to these socio-psychological perspectives). Results showed that, in isolation, all 3 predictors had medium-sized (and causal) effects. Moreover, results showed the importance of social identity in predicting collective action by supporting SIMCA's key predictions that (a) affective injustice and politicized identity produced stronger effects than those of non-affective injustice and non-politicized identity; (b) identity predicted collective action against both incidental and structural disadvantages, whereas injustice and efficacy predicted collective action against incidental disadvantages better than against structural disadvantages; (c) all 3 predictors had unique medium-sized effects on collective action when controlling for between-predictor covariance; and (d) identity bridged the injustice and efficacy explanations of collective action. Results also showed more support for SIMCA than for alternative models reflecting previous attempts at theoretical integration. The authors discuss key implications for theory, practice, future research, and further integration of social and psychological perspectives on collective action. PsycINFO Database Record (c) 2008 APA

  13. Modelling of sediment transport and morphological evolution under the combined action of waves and currents

    Directory of Open Access Journals (Sweden)

    G. Franz

    2017-09-01

    Full Text Available Coastal defence structures are often constructed to prevent beach erosion. However, poorly designed structures may cause serious erosion problems in the downdrift direction. Morphological models are useful tools to predict such impacts and assess the efficiency of defence structures for different scenarios. Nevertheless, morphological modelling is still a topic under intense research effort. The processes simulated by a morphological model depend on model complexity. For instance, undertow currents are neglected in coastal area models (2DH, which is a limitation for simulating the evolution of beach profiles for long periods. Model limitations are generally overcome by predefining invariant equilibrium profiles that are allowed to shift offshore or onshore. A more flexible approach is described in this paper, which can be generalised to 3-D models. The present work is based on the coupling of the MOHID modelling system and the SWAN wave model. The impacts of different designs of detached breakwaters and groynes were simulated in a schematic beach configuration following a 2DH approach. The results of bathymetry evolution are in agreement with the patterns found in the literature for several existing structures. The model was also tested in a 3-D test case to simulate the formation of sandbars by undertow currents. The findings of this work confirmed the applicability of the MOHID modelling system to study sediment transport and morphological changes in coastal zones under the combined action of waves and currents. The same modelling methodology was applied to a coastal zone (Costa da Caparica located at the mouth of a mesotidal estuary (Tagus Estuary, Portugal to evaluate the hydrodynamics and sediment transport both in calm water conditions and during events of highly energetic waves. The MOHID code is available in the GitHub repository.

  14. Modelling of sediment transport and morphological evolution under the combined action of waves and currents

    Science.gov (United States)

    Franz, Guilherme; Delpey, Matthias T.; Brito, David; Pinto, Lígia; Leitão, Paulo; Neves, Ramiro

    2017-09-01

    Coastal defence structures are often constructed to prevent beach erosion. However, poorly designed structures may cause serious erosion problems in the downdrift direction. Morphological models are useful tools to predict such impacts and assess the efficiency of defence structures for different scenarios. Nevertheless, morphological modelling is still a topic under intense research effort. The processes simulated by a morphological model depend on model complexity. For instance, undertow currents are neglected in coastal area models (2DH), which is a limitation for simulating the evolution of beach profiles for long periods. Model limitations are generally overcome by predefining invariant equilibrium profiles that are allowed to shift offshore or onshore. A more flexible approach is described in this paper, which can be generalised to 3-D models. The present work is based on the coupling of the MOHID modelling system and the SWAN wave model. The impacts of different designs of detached breakwaters and groynes were simulated in a schematic beach configuration following a 2DH approach. The results of bathymetry evolution are in agreement with the patterns found in the literature for several existing structures. The model was also tested in a 3-D test case to simulate the formation of sandbars by undertow currents. The findings of this work confirmed the applicability of the MOHID modelling system to study sediment transport and morphological changes in coastal zones under the combined action of waves and currents. The same modelling methodology was applied to a coastal zone (Costa da Caparica) located at the mouth of a mesotidal estuary (Tagus Estuary, Portugal) to evaluate the hydrodynamics and sediment transport both in calm water conditions and during events of highly energetic waves. The MOHID code is available in the GitHub repository.

  15. The joint space-time statistics of macroweather precipitation, space-time statistical factorization and macroweather models

    Energy Technology Data Exchange (ETDEWEB)

    Lovejoy, S., E-mail: lovejoy@physics.mcgill.ca [Physics Department, McGill University, Montreal, Quebec H3A 2T8 (Canada); Lima, M. I. P. de [Institute of Marine Research (IMAR) and Marine and Environmental Sciences Centre (MARE), Coimbra (Portugal); Department of Civil Engineering, University of Coimbra, 3030-788 Coimbra (Portugal)

    2015-07-15

    Over the range of time scales from about 10 days to 30–100 years, in addition to the familiar weather and climate regimes, there is an intermediate “macroweather” regime characterized by negative temporal fluctuation exponents: implying that fluctuations tend to cancel each other out so that averages tend to converge. We show theoretically and numerically that macroweather precipitation can be modeled by a stochastic weather-climate model (the Climate Extended Fractionally Integrated Flux, model, CEFIF) first proposed for macroweather temperatures and we show numerically that a four parameter space-time CEFIF model can approximately reproduce eight or so empirical space-time exponents. In spite of this success, CEFIF is theoretically and numerically difficult to manage. We therefore propose a simplified stochastic model in which the temporal behavior is modeled as a fractional Gaussian noise but the spatial behaviour as a multifractal (climate) cascade: a spatial extension of the recently introduced ScaLIng Macroweather Model, SLIMM. Both the CEFIF and this spatial SLIMM model have a property often implicitly assumed by climatologists that climate statistics can be “homogenized” by normalizing them with the standard deviation of the anomalies. Physically, it means that the spatial macroweather variability corresponds to different climate zones that multiplicatively modulate the local, temporal statistics. This simplified macroweather model provides a framework for macroweather forecasting that exploits the system's long range memory and spatial correlations; for it, the forecasting problem has been solved. We test this factorization property and the model with the help of three centennial, global scale precipitation products that we analyze jointly in space and in time.

  16. Space-time modeling using environmental constraints in a mobile robot system

    Science.gov (United States)

    Slack, Marc G.

    1990-01-01

    Grid-based models of a robot's local environment have been used by many researchers building mobile robot control systems. The attraction of grid-based models is their clear parallel between the internal model and the external world. However, the discrete nature of such representations does not match well with the continuous nature of actions and usually serves to limit the abilities of the robot. This work describes a spatial modeling system that extracts information from a grid-based representation to form a symbolic representation of the robot's local environment. The approach makes a separation between the representation provided by the sensing system and the representation used by the action system. Separation allows asynchronous operation between sensing and action in a mobile robot, as well as the generation of a more continuous representation upon which to base actions.

  17. Efficacy of the chemotherapeutic action of HPMA copolymer‐bound doxorubicin in a solid tumor model of ovarian carcinoma

    National Research Council Canada - National Science Library

    Minko, Tamara; Kopečková, Pavla; Kopeček, Jindřich

    2000-01-01

    Anticancer activity and main mechanisms of action of free doxorubicin (DOX) and HPMA copolymer‐bound DOX (P(GFLG)‐DOX) were studied in solid tumor mice models of DOX sensitive and resistant human ovarian carcinoma...

  18. Learning Activity Models for Multiple Agents in a Smart Space

    Science.gov (United States)

    Crandall, Aaron; Cook, Diane J.

    With the introduction of more complex intelligent environment systems, the possibilities for customizing system behavior have increased dramatically. Significant headway has been made in tracking individuals through spaces using wireless devices [1, 18, 26] and in recognizing activities within the space based on video data (see chapter by Brubaker et al. and [6, 8, 23]), motion sensor data [9, 25], wearable sensors [13] or other sources of information [14, 15, 22]. However, much of the theory and most of the algorithms are designed to handle one individual in the space at a time. Resident tracking, activity recognition, event prediction, and behavior automation becomes significantly more difficult for multi-agent situations, when there are multiple residents in the environment.

  19. When good is not always right: effect of the consequences of motor action on valence-space associations

    Directory of Open Access Journals (Sweden)

    Denis eBrouillet

    2015-03-01

    Full Text Available Since the work of Casasanto (2009, it is now well established that valence and laterality are associated. Participants tend to prefer objects presented on their dominant side over items presented on their non-dominant side, and to place good items on their dominant side and bad items on the other side. Several studies highlight that those associations of valence and laterality are accounted for by the greater motor fluency of the dominant hand and various studies noted that these associations could be reversed depending on the way people interact with their environment. Consistently with the Theory of Event Coding, the aim of this work is to show that the consequences of motor actions could also reverse the associations between valence and laterality. Thus, if participants had to place two animals (one good, one bad on two supports, one stable (no risk of falling, one unstable (risk of falling, we hypothesized that the good item would be placed on the stable support, regardless of the side where it would be put (i.e., on the dominant or non-dominant side. We expected the opposite for the bad item. The results of two experiments are consistent with this prediction and support the claim that the consequences of motor action bias the hedonic connotation of our dominant side.

  20. Modelling dendritic ecological networks in space: anintegrated network perspective

    Science.gov (United States)

    Peterson, Erin E.; Ver Hoef, Jay M.; Isaak, Dan J.; Falke, Jeffrey A.; Fortin, Marie-Josée; Jordon, Chris E.; McNyset, Kristina; Monestiez, Pascal; Ruesch, Aaron S.; Sengupta, Aritra; Som, Nicholas; Steel, E. Ashley; Theobald, David M.; Torgersen, Christian E.; Wenger, Seth J.

    2013-01-01

    Dendritic ecological networks (DENs) are a unique form of ecological networks that exhibit a dendritic network topology (e.g. stream and cave networks or plant architecture). DENs have a dual spatial representation; as points within the network and as points in geographical space. Consequently, some analytical methods used to quantify relationships in other types of ecological networks, or in 2-D space, may be inadequate for studying the influence of structure and connectivity on ecological processes within DENs. We propose a conceptual taxonomy of network analysis methods that account for DEN characteristics to varying degrees and provide a synthesis of the different approaches within

  1. The Two-Wrongs model explains perception-action dissociations for illusions driven by distortions of the egocentric reference frame

    Directory of Open Access Journals (Sweden)

    Paul eDassonville

    2015-03-01

    Full Text Available Several studies have demonstrated a dissociation of the effects of illusion on perception and action, with perception generally reported to be susceptible to illusions, while actions are seemingly immune. These findings have been interpreted to support Milner and Goodale's Two Visual Systems model, which proposes the existence of separate visual processing streams for perception and action. However, an alternative interpretation suggests that this type of behavioral dissociation will occur for any illusion that is caused by a distortion of the observer's egocentric reference frame, without requiring the existence of separate perception and action systems that are differently affected by the illusion. In this scenario, movements aimed at illusory targets will be accurate if they are guided within the same distorted reference frame used for target encoding, since the error of motor guidance will cancel with the error of encoding (hence, for actions, two wrongs do make a right. We further test this Two-Wrongs model by examining two illusions for which the hypothesis makes very different predictions: the rod-and-frame illusion (which affects perception but not actions and the simultaneous-tilt illusion (which affects perception and actions equally. We demonstrate that the rod-and-frame illusion is caused by a distortion of the observer's egocentric reference frame suitable for the cancellation of errors predicted by the Two-Wrongs model. In contrast, the simultaneous-tilt illusion is caused by local interactions between stimulus elements within an undistorted reference frame, precluding the cancellation of errors associated with the Two-Wrongs model such that the illusion is reflected in both perception and actions. These results provide evidence for a class of illusions that lead to dissociations of perception and action through distortions of the observer's spatial reference frame, rather than through the actions of functionally separate visual

  2. The Two-Wrongs model explains perception-action dissociations for illusions driven by distortions of the egocentric reference frame.

    Science.gov (United States)

    Dassonville, Paul; Reed, Scott A

    2015-01-01

    Several studies have demonstrated a dissociation of the effects of illusion on perception and action, with perception generally reported to be susceptible to illusions, while actions are seemingly immune. These findings have been interpreted to support Milner and Goodale's Two Visual Systems model, which proposes the existence of separate visual processing streams for perception and action. However, an alternative interpretation suggests that this type of behavioral dissociation will occur for any illusion that is caused by a distortion of the observer's egocentric reference frame, without requiring the existence of separate perception and action systems that are differently affected by the illusion. In this scenario, movements aimed at illusory targets will be accurate if they are guided within the same distorted reference frame used for target encoding, since the error of motor guidance will cancel with the error of encoding (hence, for actions, two wrongs do make a right). We further test this Two-Wrongs model by examining two illusions for which the hypothesis makes very different predictions: the rod-and-frame illusion (which affects perception but not actions) and the simultaneous-tilt illusion (which affects perception and actions equally). We demonstrate that the rod-and-frame illusion is caused by a distortion of the observer's egocentric reference frame suitable for the cancellation of errors predicted by the Two-Wrongs model. In contrast, the simultaneous-tilt illusion is caused by local interactions between stimulus elements within an undistorted reference frame, precluding the cancellation of errors associated with the Two-Wrongs model such that the illusion is reflected in both perception and actions. These results provide evidence for a class of illusions that lead to dissociations of perception and action through distortions of the observer's spatial reference frame, rather than through the actions of functionally separate visual processing streams.

  3. Design and implementation of space physics multi-model application integration based on web

    Science.gov (United States)

    Jiang, Wenping; Zou, Ziming

    With the development of research on space environment and space science, how to develop network online computing environment of space weather, space environment and space physics models for Chinese scientific community is becoming more and more important in recent years. Currently, There are two software modes on space physics multi-model application integrated system (SPMAIS) such as C/S and B/S. the C/S mode which is traditional and stand-alone, demands a team or workshop from many disciplines and specialties to build their own multi-model application integrated system, that requires the client must be deployed in different physical regions when user visits the integrated system. Thus, this requirement brings two shortcomings: reducing the efficiency of researchers who use the models to compute; inconvenience of accessing the data. Therefore, it is necessary to create a shared network resource access environment which could help users to visit the computing resources of space physics models through the terminal quickly for conducting space science research and forecasting spatial environment. The SPMAIS develops high-performance, first-principles in B/S mode based on computational models of the space environment and uses these models to predict "Space Weather", to understand space mission data and to further our understanding of the solar system. the main goal of space physics multi-model application integration system (SPMAIS) is to provide an easily and convenient user-driven online models operating environment. up to now, the SPMAIS have contained dozens of space environment models , including international AP8/AE8 IGRF T96 models and solar proton prediction model geomagnetic transmission model etc. which are developed by Chinese scientists. another function of SPMAIS is to integrate space observation data sets which offers input data for models online high-speed computing. In this paper, service-oriented architecture (SOA) concept that divides system into

  4. A singular K-space model for fast reconstruction of magnetic resonance images from undersampled data.

    Science.gov (United States)

    Luo, Jianhua; Mou, Zhiying; Qin, Binjie; Li, Wanqing; Ogunbona, Philip; Robini, Marc C; Zhu, Yuemin

    2017-12-09

    Reconstructing magnetic resonance images from undersampled k-space data is a challenging problem. This paper introduces a novel method of image reconstruction from undersampled k-space data based on the concept of singularizing operators and a novel singular k-space model. Exploring the sparsity of an image in the k-space, the singular k-space model (SKM) is proposed in terms of the k-space functions of a singularizing operator. The singularizing operator is constructed by combining basic difference operators. An algorithm is developed to reliably estimate the model parameters from undersampled k-space data. The estimated parameters are then used to recover the missing k-space data through the model, subsequently achieving high-quality reconstruction of the image using inverse Fourier transform. Experiments on physical phantom and real brain MR images have shown that the proposed SKM method constantly outperforms the popular total variation (TV) and the classical zero-filling (ZF) methods regardless of the undersampling rates, the noise levels, and the image structures. For the same objective quality of the reconstructed images, the proposed method requires much less k-space data than the TV method. The SKM method is an effective method for fast MRI reconstruction from the undersampled k-space data. Graphical abstract Two Real Images and their sparsified images by singularizing operator.

  5. Integration of the Radiation Belt Environment Model Into the Space Weather Modeling Framework

    Science.gov (United States)

    Glocer, A.; Toth, G.; Fok, M.; Gombosi, T.; Liemohn, M.

    2009-01-01

    We have integrated the Fok radiation belt environment (RBE) model into the space weather modeling framework (SWMF). RBE is coupled to the global magnetohydrodynamics component (represented by the Block-Adaptive-Tree Solar-wind Roe-type Upwind Scheme, BATS-R-US, code) and the Ionosphere Electrodynamics component of the SWMF, following initial results using the Weimer empirical model for the ionospheric potential. The radiation belt (RB) model solves the convection-diffusion equation of the plasma in the energy range of 10 keV to a few MeV. In stand-alone mode RBE uses Tsyganenko's empirical models for the magnetic field, and Weimer's empirical model for the ionospheric potential. In the SWMF the BATS-R-US model provides the time dependent magnetic field by efficiently tracing the closed magnetic field-lines and passing the geometrical and field strength information to RBE at a regular cadence. The ionosphere electrodynamics component uses a two-dimensional vertical potential solver to provide new potential maps to the RBE model at regular intervals. We discuss the coupling algorithm and show some preliminary results with the coupled code. We run our newly coupled model for periods of steady solar wind conditions and compare our results to the RB model using an empirical magnetic field and potential model. We also simulate the RB for an active time period and find that there are substantial differences in the RB model results when changing either the magnetic field or the electric field, including the creation of an outer belt enhancement via rapid inward transport on the time scale of tens of minutes.

  6. Using the theory of reasoned action to model retention in rural primary care physicians.

    Science.gov (United States)

    Feeley, Thomas Hugh

    2003-01-01

    Much research attention has focused on medical students', residents', and physicians' decisions to join a rural practice, but far fewer studies have examined retention of rural primary care physicians. The current review uses Fishbein and Ajzen's Theory of Reasoned Action (TRA) to organize the literature on the predictors and correlates of retention of rural practicing physicians. TRA suggests turnover behavior is directly predicted by one's turnover intentions, which are, in turn, predicted by one's attitudes about rural practice and perceptions of salient others' (eg, spouse's) attitudes about rural practice and rural living. Narrative literature review of scholarship in predicting and understanding predictors and correlates of rural physician retention. The TRA model provides a useful conceptual model to organize the literature on rural physician retention. Physicians' subjective norms regarding rural practice are an important source of influence in the decision to remain or leave one's position, and this relation should be more fully examined in future research.

  7. Pursuit of food versus pursuit of information in a Markovian perception-action loop model of foraging.

    Science.gov (United States)

    Agarwala, Edward K; Chiel, Hillel J; Thomas, Peter J

    2012-07-07

    Efficient coding, redundancy reduction, and other information theoretic optimization principles have successfully explained the organization of many biological phenomena, from the physiology of sensory receptive fields to the variability of certain DNA sequence ensembles. Here we examine the hypothesis that behavioral strategies that are optimal for survival must necessarily involve efficient information processing, and ask whether there can be circumstances in which deliberately sacrificing some information can lead to higher utility? To this end, we present an analytically tractable model for a particular instance of a perception-action loop: a creature searching for a randomly moving food source confined to a 1D ring world. The model incorporates the statistical structure of the creature's world, the effects of the creature's actions on that structure, and the creature's strategic decision process. The underlying model takes the form of a Markov process on an infinite dimensional state space. To analyze it we construct an exact coarse graining that reduces the model to a Markov process on a finite number of "information states". This mathematical technique allows us to make quantitative comparisons between the performance of an information-theoretically optimal strategy with other candidate search strategies on a food gathering task. We find that 1. Information optimal search does not necessarily optimize utility (expected food gain). 2. The rank ordering of search strategies by information performance does not predict their ordering by expected food obtained. 3. The relative advantage of different strategies depends on the statistical structure of the environment, in particular the variability of motion of the source. We conclude that there is no simple relationship between information and utility. Even in the absence of information processing costs or bandwidth constraints, behavioral optimality does not imply information efficiency, nor is there a simple

  8. Human ex-vivo action potential model for pro-arrhythmia risk assessment.

    Science.gov (United States)

    Page, Guy; Ratchada, Phachareeya; Miron, Yannick; Steiner, Guido; Ghetti, Andre; Miller, Paul E; Reynolds, Jack A; Wang, Ken; Greiter-Wilke, Andrea; Polonchuk, Liudmila; Traebert, Martin; Gintant, Gary A; Abi-Gerges, Najah

    2016-01-01

    While current S7B/E14 guidelines have succeeded in protecting patients from QT-prolonging drugs, the absence of a predictive paradigm identifying pro-arrhythmic risks has limited the development of valuable drug programs. We investigated if a human ex-vivo action potential (AP)-based model could provide a more predictive approach for assessing pro-arrhythmic risk in man. Human ventricular trabeculae from ethically consented organ donors were used to evaluate the effects of dofetilide, d,l-sotalol, quinidine, paracetamol and verapamil on AP duration (APD) and recognized pro-arrhythmia predictors (short-term variability of APD at 90% repolarization (STV(APD90)), triangulation (ADP90-APD30) and incidence of early afterdepolarizations at 1 and 2Hz to quantitatively identify the pro-arrhythmic risk. Each drug was blinded and tested separately with 3 concentrations in triplicate trabeculae from 5 hearts, with one vehicle time control per heart. Electrophysiological stability of the model was not affected by sequential applications of vehicle (0.1% dimethyl sulfoxide). Paracetamol and verapamil did not significantly alter anyone of the AP parameters and were classified as devoid of pro-arrhythmic risk. Dofetilide, d,l-sotalol and quinidine exhibited an increase in the manifestation of pro-arrhythmia markers. The model provided quantitative and actionable activity flags and the relatively low total variability in tissue response allowed for the identification of pro-arrhythmic signals. Power analysis indicated that a total of 6 trabeculae derived from 2 hearts are sufficient to identify drug-induced pro-arrhythmia. Thus, the human ex-vivo AP-based model provides an integrative translational assay assisting in shaping clinical development plans that could be used in conjunction with the new CiPA-proposed approach. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Walrus Bayesian State-space Model Output from the Bering Sea and Chukchi Sea, 2008-2012

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — State-space models offer researchers an objective approach to modeling complex animal location datasets, and state-space model behavior classifications are often...

  10. Unified Approach to Modeling and Simulation of Space Communication Networks and Systems

    Science.gov (United States)

    Barritt, Brian; Bhasin, Kul; Eddy, Wesley; Matthews, Seth

    2010-01-01

    Network simulator software tools are often used to model the behaviors and interactions of applications, protocols, packets, and data links in terrestrial communication networks. Other software tools that model the physics, orbital dynamics, and RF characteristics of space systems have matured to allow for rapid, detailed analysis of space communication links. However, the absence of a unified toolset that integrates the two modeling approaches has encumbered the systems engineers tasked with the design, architecture, and analysis of complex space communication networks and systems. This paper presents the unified approach and describes the motivation, challenges, and our solution - the customization of the network simulator to integrate with astronautical analysis software tools for high-fidelity end-to-end simulation. Keywords space; communication; systems; networking; simulation; modeling; QualNet; STK; integration; space networks

  11. Human Factors Research for Space Exploration: Measurement, Modeling, and Mitigation

    Science.gov (United States)

    Kaiser, Mary K.; Allen, Christopher S.; Barshi, Immanuel; Billman, Dorrit; Holden, Kritina L.

    2010-01-01

    As part of NASA's Human Research Program, the Space Human Factors Engineering Project serves as the bridge between Human Factors research and Human Spaceflight applications. Our goal is to be responsive to the operational community while addressing issues at a sufficient level of abstraction to ensure that our tools and solutions generalize beyond the point design. In this panel, representatives from four of our research domains will discuss the challenges they face in solving current problems while also enabling future capabilities.

  12. Dynamic Computer Model of a Stirling Space Nuclear Power System

    Science.gov (United States)

    2006-05-04

    mean temperature difference Λ neutron generation time cp average specific heat, constant pressure cpr radiator specific heat cv average...coefficient αm coolant temperature coefficient β delayed neutron fraction β regenerator porosity βw wick porosity ε radiator emissivity εr...the Systems for Nuclear Auxiliary Power ( SNAP ) program. This program resulted in the only reactor flown in space by the United States. Also, Russia

  13. Monte Carlo modeling of spatial coherence: free-space diffraction

    OpenAIRE

    Fischer, David G.; Prahl, Scott A.; Duncan, Donald D

    2008-01-01

    We present a Monte Carlo method for propagating partially coherent fields through complex deterministic optical systems. A Gaussian copula is used to synthesize a random source with an arbitrary spatial coherence function. Physical optics and Monte Carlo predictions of the first- and second-order statistics of the field are shown for coherent and partially coherent sources for free-space propagation, imaging using a binary Fresnel zone plate, and propagation through a limiting aperture. Excel...

  14. Modelling and simulation of the space mission MICROSCOPE

    Science.gov (United States)

    Bremer, Stefanie; List, Meike; Selig, Hanns; Rath, Hans; Dittus, Hansjörg

    2011-01-01

    MICROSCOPE is a French space mission for testing the weak equivalence principle (WEP). The mission goal is the determination of the Eötvös parameter η with an accuracy of 10 -15. The French space agency CNES is responsible for the satellite which is developed and produced within the Myriade series. The satellite's payload T-SAGE (Twin Space Accelerometer for Gravitation Experimentation) is developed and built by the French institute ONERA. It consists of two high-precision capacitive differential accelerometers. One accelerometer is used as reference sensor with two test masses of platinum, the science sensor contains a platinum and a titanium proof mass. The detection of the test mass movement and their control is done via a complex electrode system. As a member of the MICROSCOPE performance team, the German department ZARM will be involved in the data analysis of the MICROSCOPE mission. For this purpose, mission simulations and the preparation of the mission data evaluation in close cooperation with the French partners CNES, ONERA and OCA are realised. The development status of the simulation tool which will represent the complex spacecraft dynamics and all error sources in order to design and test data reduction procedures is presented and some features are discussed in detail.

  15. [Diagnosis of complementary feeding practices for creating a matrix model for action in primary health care].

    Science.gov (United States)

    Mais, Laís Amaral; Domene, Semíramis Martins Álvares; Barbosa, Marina Borelli; Taddei, José Augusto de Aguiar Carrazedo

    2014-01-01

    Timely and appropriate complementary feeding is essential for the healthy growth and development of children, and Primary Health Care, especially the Family Health Support Nuclei, are the ideal location for developing relevant actions during this period. A cross-sectional study that applied a questionnaire to mothers and anthropometric evaluation for 324 children sought to develop an index of complementary feeding inadequacies and to study its association with social, economic, clinical, epidemiological and nutritional variables. For quantification of feeding inadequacies, an index using the Delphi method was created. High frequencies were observed for all inadequacies, especially for late introduction of solids (80.2%), early introduction of sugar/thickeners (78.1%) and liquids (73.5%). The most significant results of these associations were early weaning of exclusive (p = 0.000) and total (p = 0.005) breastfeeding, absence of partner (p = 0.001) and the mother supporting the family financially (p = 0.025). The use of this index identifies higher-risk situations for developing a nutritional assistance action plan, especially when it comes to promoting matrix model work.

  16. Direct Visualization of Spatial and Temporal Patterns of Antimicrobial Action within Model Oral Biofilms▿

    Science.gov (United States)

    Takenaka, Shoji; Trivedi, Harsh M.; Corbin, Audrey; Pitts, Betsey; Stewart, Philip S.

    2008-01-01

    A microscopic method for noninvasively visualizing the action of an antimicrobial agent inside a biofilm was developed and applied to describe spatial and temporal patterns of mouthrinse activity on model oral biofilms. Three species biofilms of Streptococcus oralis, Streptococcus gordonii, and Actinomyces naeslundii were grown in glass capillary flow cells. Bacterial cells were stained with the fluorogenic esterase substrate Calcien AM (CAM). Loss of green fluorescence upon exposure to an antimicrobial formulation was subsequently imaged by time-lapse confocal laser scanning microscopy. When an antimicrobial mouthrinse containing chlorhexidine digluconate was administered, a gradual loss of green fluorescence was observed that began at the periphery of cell clusters where they adjoined the flowing bulk fluid and progressed inward over a time period of several minutes. Image analysis was performed to quantify a penetration velocity of 4 μm/min. An enzyme-based antimicrobial formulation led to a gradual, continually slowing loss of fluorescence in a pattern that was qualitatively different from the behavior observed with chlorhexidine. Ethanol at 11.6% had little effect on the biofilm. None of these treatments resulted in the removal of biomass from the biofilm. Most methods to measure or visualize antimicrobial action in biofilms are destructive. Spatial information is important because biofilms are known for their structural and physiological heterogeneity. The CAM staining technique has the potential to provide information about the rate of antimicrobial penetration, the presence of tolerant subpopulations, and the extent of biomass removal effected by a treatment. PMID:18223108

  17. Structural Model for the Flip-Flop Action in Thiamin Pyrophosphate-Dependent Human Pyruvate Dehydrogenase

    Science.gov (United States)

    Ciszak, Ewa; Dominiak, Paulina

    2003-01-01

    The derivative of vitamin B1 thiamin pyrophosphate (TPP) is a cofactor of enzymes performing catalysis in pathways of energy production, including (i) decarboxylation of alpha-keto acids followed by (ii) transketolation. These enzymes have shown a common mechanism of TPP activation by imposing an active V-conformation of this coenzyme that brings the N4 atom of the aminopyrimidine ring to the distance required for the intramolecular C-H N hydrogen-bonding with the C2- atom of the thiazolium ring. The reactive C2 atom of TPP is the nucleophile that attacks the carbonyl carbon of different substrates used by the TPP-dependent enzymes. The structure of the heterotetrameric human pyruvate dehydrogenase (Elp) recently determined in our laboratory (1) revealed the association pattern of the subunits and the specifics of two chemically equivalent cofactor binding sites. Dynamic nonequivalence of these two cofactor sites directs the flip-flop action of this enzyme, depending upon which two active sites effect each other (2). The crystal structure derived from the holo-form of Elp provided the basis for the model of the flip-flop action of Elp in which different steps of the catalytic reaction are performed in each of the two cofactor sites at any given moment, where these steps are governed by the concerted shuttle-like motion of the subunits. It is further proposed that balancing a hydrogen-bond network and related cofactor geometry determine the continuity of catalytic events.

  18. Combined action potential- and dynamic-clamp for accurate computational modelling of the cardiac IKr current.

    Science.gov (United States)

    Bartolucci, Chiara; Altomare, Claudia; Bennati, Marco; Furini, Simone; Zaza, Antonio; Severi, Stefano

    2015-02-01

    In the present work Action-Potential clamp (APC) and Dynamic clamp (DC) were used in combination in order to optimize the Luo-Rudy (LRd) mathematical formulation of the guinea-pig rapid delayed rectifier K(+) current (IKr), and to validate the optimized model. To this end, IKr model parameters were adjusted to fit the experimental E4031-sensitive current (IE4031) recorded under APC in guinea-pig myocytes. Currents generated by LRd model (ILRd) and the optimized one (IOpt) were then compared by testing their suitability to replace IE4031 under DC. Under APC, ILRd was significantly larger than IE4031 (mean current densities 0.51±0.01 vs 0.21±0.05pA/pF; p<0.001), mainly because of different rectification. IOpt mean density (0.17±0.01pA/pF) was similar to the IE4031 one (NS); moreover, IOpt accurately reproduced IE4031 distribution along the different AP phases. Models were then compared under DC by blocking native IKr (5μM E4031) and replacing it with ILRd or IOpt. Whereas injection of ILRd overshortened AP duration (APD90) (by 25% of its pre-block value), IOpt injection restored AP morphology and duration to overlap pre-block values. This study highlights the power of APC and DC for the identification of reliable formulations of ionic current models. An optimized model of IKr has been obtained which fully reversed E4031 effects on the AP. The model strongly diverged from the widely used Luo-Rudy formulation; this can be particularly relevant to the in silico analysis of AP prolongation caused by IKr blocking or alterations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Modelling of carcinogenic effects resulting from the combined action of radon and smoking

    Energy Technology Data Exchange (ETDEWEB)

    Ryabova, S.V.; Petin, V.G. [Medical Radiological Research Centre, Obninsk (Russian Federation)

    2002-03-01

    A simple mathematical model designed for the description of cell survival [1] and later developed for the evaluation of mutagenic effects [2] was proposed for the optimisation of the determination and prognosis of levels of carcinogenic effects in organisms, resulting from the combined action of different agents. The model postulates that the occurrence of synergism is to be expected as a result of additional carcinogenic damage arising from the interaction of sublesions induced by the two agents under investigation. These molecular sublesions are suggested to be non-carcinogenic, if each agent is taken separately. The main conclusion pertaining to this model is the existence of the highest level of synergistic effect. The model predicts the input values and conditions under which this level is reached. The synergistic effect appeared to decline with any deviation from the optimal value for the ratio of carcinogenic effects produced by each agent alone. These conclusions were verified by comparison with experimental data published by other researchers. (orig.)

  20. A latent low-dimensional common input drives a pool of motor neurons: a probabilistic latent state-space model.

    Science.gov (United States)

    Feeney, Daniel F; Meyer, François G; Noone, Nicholas; Enoka, Roger M

    2017-10-01

    Motor neurons appear to be activated with a common input signal that modulates the discharge activity of all neurons in the motor nucleus. It has proven difficult for neurophysiologists to quantify the variability in a common input signal, but characterization of such a signal may improve our understanding of how the activation signal varies across motor tasks. Contemporary methods of quantifying the common input to motor neurons rely on compiling discrete action potentials into continuous time series, assuming the motor pool acts as a linear filter, and requiring signals to be of sufficient duration for frequency analysis. We introduce a space-state model in which the discharge activity of motor neurons is modeled as inhomogeneous Poisson processes and propose a method to quantify an abstract latent trajectory that represents the common input received by motor neurons. The approach also approximates the variation in synaptic noise in the common input signal. The model is validated with four data sets: a simulation of 120 motor units, a pair of integrate-and-fire neurons with a Renshaw cell providing inhibitory feedback, the discharge activity of 10 integrate-and-fire neurons, and the discharge times of concurrently active motor units during an isometric voluntary contraction. The simulations revealed that a latent state-space model is able to quantify the trajectory and variability of the common input signal across all four conditions. When compared with the cumulative spike train method of characterizing common input, the state-space approach was more sensitive to the details of the common input current and was less influenced by the duration of the signal. The state-space approach appears to be capable of detecting rather modest changes in common input signals across conditions. NEW & NOTEWORTHY We propose a state-space model that explicitly delineates a common input signal sent to motor neurons and the physiological noise inherent in synaptic signal

  1. Granger causality mapping during joint actions reveals evidence for forward models that could overcome sensory-motor delays.

    Directory of Open Access Journals (Sweden)

    Idil Kokal

    Full Text Available Studies investigating joint actions have suggested a central role for the putative mirror neuron system (pMNS because of the close link between perception and action provided by these brain regions [1], [2], [3]. In contrast, our previous functional magnetic resonance imaging (fMRI experiment demonstrated that the BOLD response of the pMNS does not suggest that it directly integrates observed and executed actions during joint actions [4]. To test whether the pMNS might contribute indirectly to the integration process by sending information to brain areas responsible for this integration (integration network, here we used Granger causality mapping (GCM [5]. We explored the directional information flow between the anterior sites of the pMNS and previously identified integrative brain regions. We found that the left BA44 sent more information than it received to both the integration network (left thalamus, right middle occipital gyrus and cerebellum and more posterior nodes of the pMNS (BA2. Thus, during joint actions, two anatomically separate networks therefore seem effectively connected and the information flow is predominantly from anterior to posterior areas of the brain. These findings suggest that the pMNS is involved indirectly in joint actions by transforming observed and executed actions into a common code and is part of a generative model that could predict the future somatosensory and visual consequences of observed and executed actions in order to overcome otherwise inevitable neural delays.

  2. A Study of the Complex Action Problem in a Simple Model for Dynamical Compactification in Superstring Theory Using the Factorization Method

    CERN Document Server

    Anagnostopoulos, Konstantinos N; Nishimura, Jun

    2010-01-01

    The IIB matrix model proposes a mechanism for dynamically generating four dimensional space--time in string theory by spontaneous breaking of the ten dimensional rotational symmetry $\\textrm{SO}(10)$. Calculations using the Gaussian expansion method (GEM) lend support to this conjecture. We study a simple $\\textrm{SO}(4)$ invariant matrix model using Monte Carlo simulations and we confirm that its rotational symmetry breaks down, showing that lower dimensional configurations dominate the path integral. The model has a strong complex action problem and the calculations were made possible by the use of the factorization method on the density of states $\\rho_n(x)$ of properly normalized eigenvalues $\\tilde\\lambda_n$ of the space--time moment of inertia tensor. We study scaling properties of the factorized terms of $\\rho_n(x)$ and we find them in agreement with simple scaling arguments. These can be used in the finite size scaling extrapolation and in the study of the region of configuration space obscured by the...

  3. The fish gill: site of action and model for toxic effects of environmental pollutants.

    Science.gov (United States)

    Evans, D H

    1987-04-01

    The gill epithelium is the site of gas exchange, ionic regulation, acid-base balance, and nitrogenous waste excretion by fishes. The last three processes are controlled by passive and active transport of various solutes across the epithelium. Various environmental pollutants (e.g., heavy metals, acid rain, and organic xenobiotics) have been found to affect the morphology of the gill epithelium. Associated with these morphological pathologies, one finds alterations in blood ionic levels, as well as gill Na,K-activated ATPase activity and ionic fluxes. Such physiological disturbances may underly the toxicities of these pollutants. In addition, the epithelial transport steps which are affected in the fish gill model resemble those described in the human gut and kidney, sites of action of a variety of environmental toxins.

  4. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.

    Directory of Open Access Journals (Sweden)

    2005-08-01

    Full Text Available Brain dopamine is critically involved in movement control, and its deficiency is the primary cause of motor symptoms in Parkinson disease. Here we report development of an animal model of acute severe dopamine deficiency by using mice lacking the dopamine transporter. In the absence of transporter-mediated recycling mechanisms, dopamine levels become entirely dependent on de novo synthesis. Acute pharmacological inhibition of dopamine synthesis in these mice induces transient elimination of striatal dopamine accompanied by the development of a striking behavioral phenotype manifested as severe akinesia, rigidity, tremor, and ptosis. This phenotype can be reversed by administration of the dopamine precursor, L-DOPA, or by nonselective dopamine agonists. Surprisingly, several amphetamine derivatives were also effective in reversing these behavioral abnormalities in a dopamine-independent manner. Identification of dopamine transporter- and dopamine-independent locomotor actions of amphetamines suggests a novel paradigm in the search for prospective anti-Parkinsonian drugs.

  5. STERIC MASS ACTION MODEL FOR LACTOFERRIN ADSORPTION IN CRYOGEL WITH IMMOBILIZED COPPER IONS

    Directory of Open Access Journals (Sweden)

    B. M. A. Carvalho

    Full Text Available Abstract Parameters of equilibrium adsorption obtained from experiments using immobilized metal affinity chromatography (IMAC were used to evaluate the applicability of the steric mass-action (SMA model to describe the adsorption of lactoferrin to cryogel resin under different conditions. The adsorption of lactoferrin on continuous supermacroporous cryogel with immobilized Cu2+ ions was evaluated in batch adsorption experiments at different pH (6-8 and temperature (293-313 K values. Estimated values of the equilibrium constant (K and characteristic number of binding sites (n showed that these parameters decreased with increasing ionic strength, pH and temperature, while the nonlinear parameter, the steric factor (σ, increased with increasing ionic strength and temperature. Expressions correlating these parameters with pH, ionic strength and temperature were then derived.

  6. Parameter and State Estimator for State Space Models

    Directory of Open Access Journals (Sweden)

    Ruifeng Ding

    2014-01-01

    Full Text Available This paper proposes a parameter and state estimator for canonical state space systems from measured input-output data. The key is to solve the system state from the state equation and to substitute it into the output equation, eliminating the state variables, and the resulting equation contains only the system inputs and outputs, and to derive a least squares parameter identification algorithm. Furthermore, the system states are computed from the estimated parameters and the input-output data. Convergence analysis using the martingale convergence theorem indicates that the parameter estimates converge to their true values. Finally, an illustrative example is provided to show that the proposed algorithm is effective.

  7. Monte Carlo modeling of spatial coherence: free-space diffraction.

    Science.gov (United States)

    Fischer, David G; Prahl, Scott A; Duncan, Donald D

    2008-10-01

    We present a Monte Carlo method for propagating partially coherent fields through complex deterministic optical systems. A Gaussian copula is used to synthesize a random source with an arbitrary spatial coherence function. Physical optics and Monte Carlo predictions of the first- and second-order statistics of the field are shown for coherent and partially coherent sources for free-space propagation, imaging using a binary Fresnel zone plate, and propagation through a limiting aperture. Excellent agreement between the physical optics and Monte Carlo predictions is demonstrated in all cases. Convergence criteria are presented for judging the quality of the Monte Carlo predictions.

  8. Development of the Rice Convection Model as a Space Weather Tool

    Science.gov (United States)

    2015-05-31

    AFRL-RV-PS- AFRL-RV-PS- TR-2015-0129 TR-2015-0129 DEVELOPMENT OF THE RICE CONVECTION MODEL AS A SPACE WEATHER TOOL Frank R. Toffoletto, et al...Development of the Rice Convection Model as a Space Weather Tool 5a. CONTRACT NUMBER FA9453-13-1-0222 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER... Convection Model (RCM) can provide a superior space-weather product. The work under this preliminary project consisted of a modest amount of code development

  9. Survey of modeling, planning, and ground verification of space robotic systems

    Science.gov (United States)

    Xu, Wenfu; Liang, Bin; Xu, Yangsheng

    2011-06-01

    Space robotic systems are expected to play an increasingly important role in future space activities. Nevertheless, dynamics modeling and motion planning of a space robot are much more complex than those of a fixed-base robot, due to the dynamic coupling between the manipulator and its base. On the other hand, in order to assure the success of on-orbital missions, many experiments are required to verify the key algorithms on the ground before the space robot is launched. In this paper, the main research achievements on dynamics modeling, path planning, and ground verification are reviewed, and future studies are recommended. Firstly, we summarize the essential modeling concepts, and deduce the kinematics and dynamics equations of a space robot. Secondly, the main motion planning approaches are discussed. Then, different ground verification systems, including the air-bearing table, neutral buoyancy, airplane flying, free-falling motion, suspension system, and hybrid system, are introduced. Finally, the future research trends are forecasted.

  10. The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer

    Science.gov (United States)

    Brown, Nadine M.; Belles, Carrie A.; Lindley, Stephanie L.; Zimmer-Nechemias, Linda D.; Zhao, Xueheng; Witte, David P.; Kim, Mi-Ok; Setchell, Kenneth D.R.

    2010-01-01

    We describe for the first time the chemopreventive effects of S-(−)equol and R-(+)equol, diastereoisomers with contrasting affinities for estrogen receptors (ERs). S-(−)equol, a ligand for ERβ, is an intestinally derived metabolite formed by many humans and by rodents consuming diets containing soy isoflavones. Whether the well-documented chemopreventive effect of a soy diet could be explained by equol's action was unclear because neither diastereoisomers had been tested in animal models of chemoprevention. Sprague–Dawley rats (n = 40–41 per group) were fed a soy-free AIN-93G diet or an AIN-93G diet supplemented with 250 mg/kg of S-(−)equol or R-(+)equol beginning day 35. On day 50, mammary tumors were induced by dimethylbenz[a]anthracene and thereafter, animals were palpated for number and location of tumors. On day 190, animals were killed and mammary tumors were removed and verified by histology, and the degree of invasiveness and differentiation was determined. S-(−)equol and R-(+)equol plasma concentrations measured on days 35, 100 and 190 by tandem mass spectrometry confirmed diet compliance and no biotransformation of either diastereoisomer. In this model, S-(−)equol had no chemopreventive action, nor was it stimulatory. In contrast, R-(+)equol compared with Controls reduced palpable tumors (P = 0.002), resulted in 43% fewer tumors (P = 0.004), increased tumor latency (88.5 versus 66 days, P = 0.003), and tumors were less invasive but showed no difference in pattern grade or mitosis. Both enantiomers had no effect on absolute uterine weight but caused a significant reduction in body weight gain. In conclusion, the novel finding that the unnatural enantiomer, R-(+)equol, was potently chemopreventive warrants investigation of its potential for breast cancer prevention and treatment. PMID:20110282

  11. Visual Middle-Out Modeling of Problem Spaces

    DEFF Research Database (Denmark)

    Valente, Andrea

    2009-01-01

    Modeling is a complex and central activity in many domains. Domain experts and designers usually work by drawing and create models from the middle-out; however, visual and middle-out style modeling is poorly supported by software tools. In order to define a new class of software-based modeling...... tools, we propose a scenario and identify some requirements. Those requirements are contrasted against features of existing tools from various application domains, and the results show general lack of support for custom visualization and incremental knowledge specification, poor handling of temporal...

  12. Modeling vitamin D actions in triple negative/basal-like breast cancer.

    Science.gov (United States)

    LaPorta, Erika; Welsh, JoEllen

    2014-10-01

    Breast cancer is a heterogeneous disease with six molecularly defined subtypes, the most aggressive of which are triple negative breast cancers that lack expression of estrogen receptor (ER) and progesterone receptor (PR) and do not exhibit amplification of the growth factor receptor HER2. Triple negative breast cancers often exhibit basal-like gene signatures and are enriched for CD44+ cancer stem cells. In this report we have characterized the molecular actions of the VDR in a model of triple negative breast cancer. Estrogen independent, invasive mammary tumor cell lines established from wild-type (WT) and VDR knockout (VDRKO) mice were used to demonstrate that VDR is necessary for 1,25-dihydroxyvitamin D3 (1,25D) mediated anti-cancer actions in vitro and to identify novel targets of this receptor. Western blotting confirmed differential VDR expression and demonstrated the lack of ER, PR and Her2 in these cell lines. Re-introduction of human VDR (hVDR) into VDRKO cells restored the anti-proliferative actions of 1,25D. Genomic profiling demonstrated that 1,25D failed to alter gene expression in KO240 cells whereas major changes were observed in WT145 cells and in KO clones stably expressing hVDR (KO(hVDR) cells). With a 2-fold cutoff, 117 transcripts in WT145 cells and 197 transcripts in the KO(hVDR) clones were significantly altered by 1,25D. Thirty-five genes were found to be commonly regulated by 1,25D in all VDR-positive cell lines. Of these, we identified a cohort of four genes (Plau, Hbegf, Postn, Has2) that are known to drive breast cancer invasion and metastasis whose expression was markedly down regulated by 1,25D. These data support a model whereby 1,25D coordinately suppresses multiple proteins that are required for survival of triple-negative/basal-like breast cancer cells. Since studies have demonstrated a high prevalence of vitamin D deficiency in women with basal-like breast cancer, correction of vitamin D deficiency in these women represents a

  13. Testing Different Survey Techniques to Model Architectonic Narrow Spaces

    Science.gov (United States)

    Mandelli, A.; Fassi, F.; Perfetti, L.; Polari, C.

    2017-08-01

    In the architectural survey field, there has been the spread of a vast number of automated techniques. However, it is important to underline the gap that exists between the technical specification sheet of a particular instrument and its usability, accuracy and level of automation reachable in real cases scenario, especially speaking about Cultural Heritage (CH) field. In fact, even if the technical specifications (range, accuracy and field of view) are known for each instrument, their functioning and features are influenced by the environment, shape and materials of the object. The results depend more on how techniques are employed than the nominal specifications of the instruments. The aim of this article is to evaluate the real usability, for the 1:50 architectonic restitution scale, of common and not so common survey techniques applied to the complex scenario of dark, intricate and narrow spaces such as service areas, corridors and stairs of Milan's cathedral indoors. Tests have shown that the quality of the results is strongly affected by side-issues like the impossibility of following the theoretical ideal methodology when survey such spaces. The tested instruments are: the laser scanner Leica C10, the GeoSLAM ZEB1, the DOT DPI 8 and two photogrammetric setups, a full frame camera with a fisheye lens and the NCTech iSTAR, a panoramic camera. Each instrument presents advantages and limits concerning both the sensors themselves and the acquisition phase.

  14. Application of artificial intelligence (AI) concepts to the development of space flight parts approval model

    Science.gov (United States)

    Krishnan, Govindarajapuram Subramaniam

    1997-12-01

    The National Aeronautics & Space Administration (NASA), the European Space Agency (ESA), and the Canadian Space Agency (CSA) missions involve the performance of scientific experiments in Space. Instruments used in such experiments are fabricated using electronic parts such as microcircuits, inductors, capacitors, diodes, transistors, etc. For instruments to perform reliably the selection of commercial parts must be monitored and strictly controlled. The process used to achieve this goal is by a manual review and approval of every part used to build the instrument. The present system to select and approve parts for space applications is manual, inefficient, inconsistent, slow and tedious, and very costly. In this dissertation a computer based decision support model is developed for implementing this process using artificial intelligence concepts based on the current information (expert sources). Such a model would result in a greater consistency, accuracy, and timeliness of evaluation. This study presents the methodology of development and features of the model, and the analysis of the data pertaining to the performance of the model in the field. The model was evaluated for three different part types by experts from three different space agencies. The results show that the model was more consistent than the manual evaluation for all part types considered. The study concludes with the cost and benefits analysis of implementing the models and shows that implementation of the model will result in significant cost savings. Other implementation details are highlighted.

  15. DESCRIPTION OF MODELING ANALYSES IN SUPPORT OF THE 200-ZP-1 REMEDIAL DESIGN/REMEDIAL ACTION

    Energy Technology Data Exchange (ETDEWEB)

    VONGARGEN BH

    2009-11-03

    The Feasibility Study/or the 200-ZP-1 Groundwater Operable Unit (DOE/RL-2007-28) and the Proposed Plan/or Remediation of the 200-ZP-1 Groundwater Operable Unit (DOE/RL-2007-33) describe the use of groundwater pump-and-treat technology for the 200-ZP-1 Groundwater Operable Unit (OU) as part of an expanded groundwater remedy. During fiscal year 2008 (FY08), a groundwater flow and contaminant transport (flow and transport) model was developed to support remedy design decisions at the 200-ZP-1 OU. This model was developed because the size and influence of the proposed 200-ZP-1 groundwater pump-and-treat remedy will have a larger areal extent than the current interim remedy, and modeling is required to provide estimates of influent concentrations and contaminant mass removal rates to support the design of the aboveground treatment train. The 200 West Area Pre-Conceptual Design/or Final Extraction/Injection Well Network: Modeling Analyses (DOE/RL-2008-56) documents the development of the first version of the MODFLOW/MT3DMS model of the Hanford Site's Central Plateau, as well as the initial application of that model to simulate a potential well field for the 200-ZP-1 remedy (considering only the contaminants carbon tetrachloride and technetium-99). This document focuses on the use of the flow and transport model to identify suitable extraction and injection well locations as part of the 200 West Area 200-ZP-1 Pump-and-Treat Remedial Design/Remedial Action Work Plan (DOEIRL-2008-78). Currently, the model has been developed to the extent necessary to provide approximate results and to lay a foundation for the design basis concentrations that are required in support of the remedial design/remediation action (RD/RA) work plan. The discussion in this document includes the following: (1) Assignment of flow and transport parameters for the model; (2) Definition of initial conditions for the transport model for each simulated contaminant of concern (COC) (i.e., carbon

  16. Modelling of Structural Loads in Drag Augmented Space Debris Removal Concepts

    DEFF Research Database (Denmark)

    Kristensen, Anders Schmidt; Nikolajsen, Jan Ánike; Lauridsen, Peter Riddersholm

    2017-01-01

    A Self-deployable Deorbiting Space Structure (SDSS) is used for drag augmented space debris removal. A highly flexible frame allows for a folding of the structure by bifurcation. This research models the structural loads during the deployment and unfolding of the drag sail in Low Earth Orbit (LEO...

  17. Spacing and repetition effects in human memory: application of the SAM model

    National Research Council Canada - National Science Library

    Raaijmakers, Jeroen G.W

    2003-01-01

    ... the probability of storing the trace in long-term memory (e.g., models of the all-or-none type, Bower, 1961 ), or increase the strength of the trace. A related issue concerns the effects of spacing of individual repetitions. A well-known phenomenon that has been observed in many learning paradigms is the distributed practice or spacing effect . As ...

  18. A state-space model for residential real estate valuation

    NARCIS (Netherlands)

    Francke, M.

    2010-01-01

    All property in the Netherlands has to be appraised yearly. Yearly valuation has only been made possible with the help of models. The number of real estate appraisers is simply too small to value the more than 7 million residential properties. This paper describes the statistical model that is used

  19. Mathematical Model for Direct Evaporative Space Cooling Systems ...

    African Journals Online (AJOL)

    This paper deals with the development of a simple mathematical model for experimental validation of the performance of a small evaporative cooling system in a tropical climate. It also presents the coefficient of convective heat transfer of wide range of temperatures based on existing model. Extensive experiments have ...

  20. Hyperstate matrix models : extending demographic state spaces to higher dimensions

    NARCIS (Netherlands)

    Roth, G.; Caswell, H.

    2016-01-01

    1. Demographic models describe population dynamics in terms of the movement of individuals among states (e.g. size, age, developmental stage, parity, frailty, physiological condition). Matrix population models originally classified individuals by a single characteristic. This was enlarged to two