WorldWideScience

Sample records for actinium 235

  1. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-08-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1- ligands (3.2+/-1.1) than AmIII (0.8+/-0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour.

  2. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac–Cl and Ac–OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1– ligands (3.2±1.1) than AmIII (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour. PMID:27531582

  3. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  4. Production of high-purity radium-223 from legacy actinium-beryllium neutron sources.

    Science.gov (United States)

    Soderquist, Chuck Z; McNamara, Bruce K; Fisher, Darrell R

    2012-07-01

    Radium-223 is a short-lived alpha-particle-emitting radionuclide with potential applications in cancer treatment. Research to develop new radiopharmaceuticals employing (223)Ra has been hindered by poor availability due to the small quantities of parent actinium-227 available world-wide. The purpose of this study was to develop innovative and cost-effective methods to obtain high-purity (223)Ra from (227)Ac. We obtained (227)Ac from two surplus actinium-beryllium neutron generators. We retrieved the actinium/beryllium buttons from the sources and dissolved them in a sulfuric-nitric acid solution. A crude actinium solid was recovered from the solution by coprecipitation with thorium fluoride, leaving beryllium in solution. The crude actinium was purified to provide about 40 milligrams of actinium nitrate using anion exchange in methanol-water-nitric acid solution. The purified actinium was then used to generate high-purity (223)Ra. We extracted (223)Ra using anion exchange in a methanol-water-nitric acid solution. After the radium was separated, actinium and thorium were then eluted from the column and dried for interim storage. This single-pass separation produces high purity, carrier-free (223)Ra product, and does not disturb the (227)Ac/(227)Th equilibrium. A high purity, carrier-free (227)Th was also obtained from the actinium using a similar anion exchange in nitric acid. These methods enable efficient production of (223)Ra for research and new alpha-emitter radiopharmaceutical development.

  5. Temporal Variations in Surface Concentrations of Terrestrial Lead 210 and Uranium 235 Radionucleides

    Science.gov (United States)

    Yoshimori, M.

    We have started to measure the surface concentrations of terrestrial radionucleides of lead 210 and uranium 235 in Tokyo (N35, E139) in 2002. Lead 210 which is a daughter nucleus of Rn-222 (uranium series) emits 46 keV gamma-ray with a half-life of 22.4 years, while uranium 235 (actinium series) emits a gamma-ray at 186 keV with a half-life of 0.7 billion years. The present measurement of the surface concentration of lead 210 exhibits two peaks in spring and fall, similar to the beryllium 7 seasonal variations, while the uranium 235 concentration does not vary with time within statistical errors. These two terrestrial radionucleides exhibit different temporal variations on the surface. We discuss possible explanations for the differences in the temporal variations from a point of view of differences in their altitude distribution.

  6. Relativistic small-core pseudopotentials for actinium, thorium, and protactinium.

    Science.gov (United States)

    Weigand, Anna; Cao, Xiaoyan; Hangele, Tim; Dolg, Michael

    2014-04-03

    Small-core pseudopotentials for actinium, thorium, and protactinium have been energy-adjusted to multiconfiguration Dirac-Hartree-Fock reference data based on the Dirac-Coulomb-Breit Hamiltonian and the Fermi nucleus model. Corresponding optimized valence basis sets of polarized valence quadruple-ζ quality are presented. Atomic test calculations for the first four ionization potentials show satisfactory results at both the Hartree-Fock and the multireference averaged coupled-pair functional level. Highly correlated Fock-space coupled cluster calculations demonstrate that the new pseudopotentials yield ionization potentials, which are in excellent agreement with corresponding all-electron results and experimental data. The pseudopotentials and basis sets supplement a similar set previously published for uranium.

  7. 31 CFR 540.315 - Uranium-235 (U235).

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Uranium-235 (U235). 540.315 Section... FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY HIGHLY ENRICHED URANIUM (HEU) AGREEMENT ASSETS CONTROL REGULATIONS General Definitions § 540.315 Uranium-235 (U235). The term uranium-235 or U235 means the...

  8. Effects of spin-orbit coupling on actinium under pressure

    Energy Technology Data Exchange (ETDEWEB)

    Rubio-Ponce, A.; Rivera, J. [Departamento de Ciencias Basicas, Universidad Autonoma Metropolitana-Azcapotzalco, Mexico (Mexico); Olguin, D. [Departamento de Fi sica, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico (Mexico)

    2015-04-15

    Actinium (Ac) is a radioactive metal and the first element of the actinide series. At ambient conditions Ac crystallizes in the fcc lattice, however, up to date its phase diagram is unknown. In the present work, we have studied the structural and electronic properties of Ac under hydrostatic pressure assuming the fcc structure as well as three hypothetical structures, namely the hcp, bcc, and sc, and for pressures up to 100 GPa. From our calculations, we found only one structural transition allowed, from the fcc to hcp, our calculated pressure was 39.85 GPa. The calculations were performed by means of the full potential linearized augmented plane wave (FLAPW) method and the generalized gradient approximation (GGA) for the exchange-correlation energy, where we have included in our study the spin-orbit coupling which is important for heavy elements. The total energy results were fitted to the third order Birch-Murnaghan's equation of state. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  9. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  10. Report for General Research September 18 to December 11, 1950 (Actinium Volume)

    Energy Technology Data Exchange (ETDEWEB)

    Haring, M.M.

    1951-01-15

    The purpose of the research work presented in this volume is to develop a process for the separation and purification of actinium-227 produced by neutron bombardment of radium-226 and to develop methods by which uniform films of actinium metal may be deposited on metallic surfaces. The design work on the cave structure and mechanical equipment used in the actinium separation is proceeding on schedule. As the mechanical design phase is nearing completion the emphasis is being directed toward processing equipment. The process as well as the mechanical equipment has been adapted from the research work of F. T. Hagemann and the Remote Control Group at Argonne National Laboratory. Consequently, one of the first objectives is to become familiary with the chemistry of the process and the operation of the mechanical equipment. Cold runs have been made on the T.T.A. benzene extraction using lanthanum and barium in place of actinium and radium. No difficulty with the operation was observed. The formation of precipitates was one of the difficulties encountered with the process as the precipitates carry radium. It has been found that metals such as nickel cause these precipitates to form and should, therefore, be avoided in the construction of equipment. it was also found that a T.T.A. solution exposed to 0.5 curie of polonium over a period of days develops a precipitate. Some new mechanical features hav eshown promise. The use of copper-coated glassware which will hold together even though the glass is cracked has made it possible to replace custom-built heaters with standard heating mantles. A new graphite, silicone grease mixture appears to hold up in stopcocks handling benzene and, as a result, may eliminate the necessary of entering the cave for regreasing. Tests on the preparation of dense concrete have given results which meet the shielding requirements for the cave. A strippable paint and tape combination has been studied and specified to provide for decontamination of

  11. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    Energy Technology Data Exchange (ETDEWEB)

    Momeni, M.H.

    1981-09-01

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore.

  12. Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes.

    Science.gov (United States)

    Radchenko, V; Engle, J W; Wilson, J J; Maassen, J R; Nortier, F M; Taylor, W A; Birnbaum, E R; Hudston, L A; John, K D; Fassbender, M E

    2015-02-06

    Actinium-225 (t1/2=9.92d) is an α-emitting radionuclide with nuclear properties well-suited for use in targeted alpha therapy (TAT), a powerful treatment method for malignant tumors. Actinium-225 can also be utilized as a generator for (213)Bi (t1/2 45.6 min), which is another valuable candidate for TAT. Actinium-225 can be produced via proton irradiation of thorium metal; however, long-lived (227)Ac (t1/2=21.8a, 99% β(-), 1% α) is co-produced during this process and will impact the quality of the final product. Thus, accurate assays are needed to determine the (225)Ac/(227)Ac ratio, which is dependent on beam energy, irradiation time and target design. Accurate actinium assays, in turn, require efficient separation of actinium isotopes from both the Th matrix and highly radioactive activation by-products, especially radiolanthanides formed from proton-induced fission. In this study, we introduce a novel, selective chromatographic technique for the recovery and purification of actinium isotopes from irradiated Th matrices. A two-step sequence of cation exchange and extraction chromatography was implemented. Radiolanthanides were quantitatively removed from Ac, and no non-Ac radionuclidic impurities were detected in the final Ac fraction. An (225)Ac spike added prior to separation was recovered at ≥ 98%, and Ac decontamination from Th was found to be ≥ 10(6). The purified actinium fraction allowed for highly accurate (227)Ac determination at analytical scales, i.e., at (227)Ac activities of 1-100 kBq (27 nCi to 2.7 μCi). Copyright © 2014 Elsevier B.V. All rights reserved.

  13. 32 CFR 235.5 - Responsibilities.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 235.5 Section 235.5 National... SALE OR RENTAL OF SEXUALLY EXPLICIT MATERIAL ON DOD PROPERTY § 235.5 Responsibilities. (a) The... its responsibilities as set forth in § 235.6. (b) The Secretaries of the Military Departments shall...

  14. 235

    African Journals Online (AJOL)

    2003-05-01

    May 1, 2003 ... were low in Nairobi province, although the proportion of pupils who had smoked at least ..... ratios and indicate a statistically significant relationships if both ..... A study carried out in Kampala and Mbale districts. Master. Thesis.

  15. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

    Science.gov (United States)

    Henriksen, Gjermund; Bruland, Oyvind S; Larsen, Roy H

    2004-01-01

    The present study explores the use of alpha-particle-emitting, bone-seeking agents as candidates for targeted radiotherapy. Actinium and thorium 1,4,7,10 tetraazacyclododecane N,N',N'',N''' 1,4,7,10-tetra(methylene) phosphonic acid (DOTMP) and thorium-diethylene triamine N,N',N'' penta(methylene) phosphonic acid (DTMP) were prepared and their biodistribution evaluated in conventional Balb/C mice at four hours after injection. All three bone-seeking agents showed a high uptake in bone and a low uptake in soft tissues. Among the soft tissue organs, only kidney had a relatively high uptake. The femur/kidney ratios for 227Th-DTMP, 228-Ac-DOTMP and 227Th-DOTMP were 14.2, 7.6 and 6.0, respectively. A higher liver uptake of 228Ac-DOTMP was seen than for 227Th-DTMP and 227Th-DOTMP. This suggests that some demetallation of the 228Ac-DOTMP complex had occurred. The results indicate that 225Ac-DOTMP, 227Th-DOTMP and 227Th-DTMP have promising properties as potential therapeutic bone-seeking agents.

  16. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Energy Technology Data Exchange (ETDEWEB)

    Raeder, S., E-mail: s.raeder@gsi.de [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Bastin, B. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Block, M. [Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Institut für Kernchemie, Johannes Gutenberg Universität, 55128 Mainz (Germany); Creemers, P. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Delahaye, P. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Ferrer, R. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fléchard, X. [LPC Caen, ENSICAEN, Université de Caen, CNRS/IN2P3, Caen (France); Franchoo, S. [Institute de Physique Nucléaire (IPN) d’Orsay, 91406 Orsay, Cedex (France); Ghys, L. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); SCK-CEN, Belgian Nuclear Research Center, Boeretang 200, 2400 Mol (Belgium); Gaffney, L.P.; Granados, C. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Heinke, R. [Institut für Physik, Johannes Gutenberg Universität, 55128 Mainz (Germany); Hijazi, L. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); and others

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  17. 14 CFR 121.235 - Fuel valves.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fuel valves. 121.235 Section 121.235..., FLAG, AND SUPPLEMENTAL OPERATIONS Special Airworthiness Requirements § 121.235 Fuel valves. Each fuel valve must— (a) Comply with § 121.257; (b) Have positive stops or suitable index provisions in the...

  18. 33 CFR 136.235 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.235 Section 136.235 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.235...

  19. 7 CFR 235.3 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 235.3 Section 235.3 Agriculture... CHILD NUTRITION PROGRAMS STATE ADMINISTRATIVE EXPENSE FUNDS § 235.3 Administration. (a) Within the Department, FNS shall act on behalf of the Department in the administration of the program for payment...

  20. 32 CFR 235.4 - Policy.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 235.4 Section 235.4 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS SALE OR RENTAL OF SEXUALLY EXPLICIT MATERIAL ON DOD PROPERTY § 235.4 Policy. It is DoD policy that: (a) No...

  1. 46 CFR 108.235 - Construction.

    Science.gov (United States)

    2010-10-01

    ... limit drop test in 14 CFR 29.725, or a load of not less than 75 percent of the helicopter maximum weight... 46 Shipping 4 2010-10-01 2010-10-01 false Construction. 108.235 Section 108.235 Shipping COAST... Construction and Arrangement Helicopter Facilities § 108.235 Construction. (a) Each helicopter deck must...

  2. Dicty_cDB: SLA235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLA235 (Link to dictyBase) - - - Contig-U16325-1 SLA235E (Link... to Original site) - - - - - - SLA235E 470 Show SLA235 Library SL (Link to library) Clone ID SLA235 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLA2-B/SLA235Q.Seq.d/ Representative seq. ID SLA23...5E (Link to Original site) Representative DNA sequence >SLA235 (SLA235Q) /CSM/SL/SLA2-B/SLA235Q.Seq.d/ CCAAA...GTTTTTAAAAAAAAAA AAAAAAATAATTATTAAATTTTTAAAATTATAAATAATAATCTTCTTATG sequence update 1997. 5. 7 Transla

  3. 24 CFR 901.235 - Technical assistance.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Technical assistance. 901.235... DEVELOPMENT PUBLIC HOUSING MANAGEMENT ASSESSMENT PROGRAM § 901.235 Technical assistance. (a) The Department may provide technical assistance to a PHA that is in substantial default. (b) The Department may...

  4. 33 CFR 105.235 - Communications.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Communications. 105.235 Section... MARITIME SECURITY: FACILITIES Facility Security Requirements § 105.235 Communications. (a) The Facility... conditions at the facility. (b) Communication systems and procedures must allow effective and...

  5. Enrichment Monitor for 235U Fuel Tubes

    Energy Technology Data Exchange (ETDEWEB)

    Winn, W.G.

    2001-08-22

    This report describes the performance of this prototype y-monitor of 235 Uranium enrichment. In this proposed method y-rates associated with 235U and 232U are correlated with enrichment. Instrumentation for appraising fuel tubes with this method has been assembled and tested.

  6. 45 CFR 235.61 - Definition of terms.

    Science.gov (United States)

    2010-10-01

    ... ASSISTANCE PROGRAMS § 235.61 Definition of terms. For purposes of §§ 235.60-235.66: Act means the Social... 45 Public Welfare 2 2010-10-01 2010-10-01 false Definition of terms. 235.61 Section 235.61 Public... new employees to assume job responsibilities. (b) Continuing training means an on-going program...

  7. Origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department); Origine des elements de la famille de l'uranium-235 observes dans la riviere Ellez a proximite du reacteur nucleaire experimental EL4 en cours de demantelement (Mont d'Arree - departement du Finistere). Resultats et premiers constats annee 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 ({sup 227}Ac), non born by its ascendents which are {sup 235}U and {sup 231}Pa is observed. This phenomenon is characterized by mass activities superior to these ones of {sup 235}U and able to reach these ones of {sup 238}U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil ({sup 210}Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  8. Dicty_cDB: SLC235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLC235 (Link to dictyBase) - - - Contig-U10207-1 SLC235E (Link to Original site) SLC...235F 708 SLC235Z 582 SLC235P 1290 SLC235E 1198 Show SLC235 Library SL (Link to library) Clone ID SLC...ginal site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SL/SLC2-B/SLC235Q.Seq.d/ Representative seq. ID SLC...235E (Link to Original site) Representative DNA sequence >SLC235 (SLC235Q) /CSM/SL/SLC2-B/SLC...FGGGVDLTPVYPKLDQVVEFSFNIEKSMRPIWPRGEQNLIRIG*grm*qlflpst *r*npwrwwfixrss*ir*skdlevhlpirfiihrsl*tipc***fnll**sskristis sfslc

  9. 24 CFR 235.206 - Substitute mortgagors.

    Science.gov (United States)

    2010-04-01

    ... MORTGAGE INSURANCE AND ASSISTANCE PAYMENTS FOR HOME OWNERSHIP AND PROJECT REHABILITATION Contract Rights and Obligations-Homes for Lower Income Families § 235.206 Substitute mortgagors. (a) Selling mortgagor... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Substitute mortgagors....

  10. 32 CFR 235.3 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... Exchanges, and ship stores. Sexually explicit material. Material, the dominant theme of which is the... SALE OR RENTAL OF SEXUALLY EXPLICIT MATERIAL ON DOD PROPERTY § 235.3 Definitions. For the purpose of this part, the following definitions apply: Dominant theme. A theme of any material that is superior...

  11. Dicty_cDB: VSC235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VS (Link to library) VSC235 (Link to dictyBase) - G21287 DDB0189760 Contig-U16307-1 VSC...235Z (Link to Original site) - - VSC235Z 315 - - - - Show VSC235 Library VS (Link to library) Clone ID VSC...riginal site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VS/VSC2-B/VSC235Q.Seq.d/ ...Representative seq. ID VSC235Z (Link to Original site) Representative DNA sequence >VSC235 (VSC235Q) /CSM/VS/VSC2-B/VSC...*vikilmifqmiyikilmvn*nhklkn Homology vs CSM-cDNA Score E Sequences producing significant alignments: (bits) Value VSC235 (VSC

  12. 49 CFR 192.235 - Preparation for welding.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Preparation for welding. 192.235 Section 192.235... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Welding of Steel in Pipelines § 192.235 Preparation for welding. Before beginning any welding, the welding surfaces must be clean and free of any material...

  13. 8 CFR 235.6 - Referral to immigration judge.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Referral to immigration judge. 235.6 Section 235.6 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS INSPECTION OF PERSONS APPLYING FOR ADMISSION § 235.6 Referral to immigration judge. (a) Notice—(1) Referral by Form...

  14. 33 CFR 117.235 - Chesapeake and Delaware Canal.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Chesapeake and Delaware Canal. 117.235 Section 117.235 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Delaware § 117.235 Chesapeake and Delaware Canal. The draw of the Conrail bridge, mile...

  15. 42 CFR 403.235 - Review and certification of policies.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Review and certification of policies. 403.235 Section 403.235 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Certification Program: General Provisions § 403.235 Review and certification of policies. (a) CMS will...

  16. 48 CFR 252.235-7002 - Animal welfare.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Animal welfare. 252.235... Clauses 252.235-7002 Animal welfare. As prescribed in 235.072(a), use the following clause: Animal Welfare... contractors with approved Public Health Service Welfare Assurances. (e) The Contractor may...

  17. 7 CFR 58.235 - Modified dry milk products.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Modified dry milk products. 58.235 Section 58.235... Materials § 58.235 Modified dry milk products. Dry milk products to which approved neutralizing agents or... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) GRADING AND...

  18. Decay scheme of the U{sup 2}35; Esquema de desintegracion del U-235

    Energy Technology Data Exchange (ETDEWEB)

    Gaeta, R.

    1965-07-01

    A study of the Th{sup 2}31 excited levels from the alpha decay of the U{sup 2}35, is carried out. The alpha particle spectrum was measured by means of a semiconductor counter spectrometer with an effective resolution of 18 keV. Nineteen new lines were identified. The gamma-ray spectrum was measured with thin samples of U{sup 2}35, free from decay products, and in such geometrical conditions, that most of the interference effects were eliminated. The gamma-gamma coincidence spectra have made easier a better knowledge of the transition between the several levels. (Author) 110 refs.

  19. 48 CFR 235.017-1 - Sponsoring agreements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Sponsoring agreements. 235.017-1 Section 235.017-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... Sponsoring agreements. (c)(4) DoD-sponsoring FFRDCs that function primarily as research laboratories (C3I...

  20. 45 CFR 235.63 - Conditions for FFP.

    Science.gov (United States)

    2010-10-01

    ... completion of training unless precluded by merit system requirements, legislative budget cuts, position... 45 Public Welfare 2 2010-10-01 2010-10-01 false Conditions for FFP. 235.63 Section 235.63 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...

  1. 47 CFR 90.235 - Secondary fixed signaling operations.

    Science.gov (United States)

    2010-10-01

    ... a secondary basis for voice, tone or impulse signaling on a licensee's mobile service frequency(ies... Section 90.235 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.235...

  2. 48 CFR 235.072 - Additional contract clauses.

    Science.gov (United States)

    2010-10-01

    ... involving research on live vertebrate animals. (b) Use the clause at 252.235-7003, Frequency Authorization... 252.235-7011, Final Scientific or Technical Report, in solicitations and contracts for research and... SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING...

  3. 77 FR 29986 - Savannah River Site Building 235-F Safety

    Science.gov (United States)

    2012-05-21

    ... indicated that the concrete stack, prior to the height reduction, could have collapsed onto Building 235-F... components such as ventilation ducts. The draft BIO states that the metal ventilation ducts may leak after an... 235-F radiological drill involving the adjacent Mixed Oxide Fuel Fabrication Facility or...

  4. A consecutive series of 235 epigastric hernias.

    Science.gov (United States)

    Ponten, J E H; Leenders, B J M; Charbon, J A; Nienhuijs, S W

    2015-10-01

    Epigastric herniation is a common, though not always symptomatic condition. It is likely, that in accordance to the tension-free principles for other hernias, epigastric hernia repair should be mesh based. Patients from two large hospitals were investigated retrospectively if they were operated on an epigastric hernia for the past 6 years. Follow-up was completed with a postal questionnaire. A total of 235 patients (50 % male) were operated. Sixty-eight patients were operated with mesh and 167 patients with suture repair. Forty-six patients were loss-to follow-up (19.6 %). In the mesh operated patients the recurrence rate was 10.9 % (n = 6) compared to 14.9 % (n = 20) in the suture repair group. Cox-regression analysis showed an increased risk for recurrence in the suture repair group (odds ratio 1.43; 95 % CI 0.56-3.57; p = 0.44). Operation time for mesh repair (47 min) was significantly longer compared to suture repair (29 min) (p hernias. A total of 51 patients smoked and 14 patients had diabetes mellitus. Fourteen patients used steroids and 22 patients suffered from a chronic lung disease. Subgroup analysis showed a significant difference for pain in patients in which re-operation for a recurrence occurred (p = 0.004). This is one of the largest reported series on solely epigastric hernias. A recurrence occurred more often after sutured repair compared to mesh repair. No differences in chronic pain was seen between mesh and suture repaired patients. Male:female ratio of 1:1, which is different from the 3:1 ratio found in previous older smaller studies, could be more reliable.

  5. Nuclear Excitation by Electronic Transition of U-235

    Energy Technology Data Exchange (ETDEWEB)

    Chodash, Perry Adam [Univ. of California, Berkeley, CA (United States)

    2015-07-14

    Nuclear excitation by electronic transition (NEET) is a rare nuclear excitation that is theorized to occur in numerous isotopes. One isotope in particular, 235U, has been studied several times over the past 40 years and NEET of 235U has never been conclusively observed. These past experiments generated con icting results with some experiments claiming to observe NEET of 235U and others setting limits for the NEET rate. This dissertation discusses the latest attempt to measure NEET of 235U. If NEET of 235U were to occur, 235mU would be created. 235mU decays by internal conversion with a decay energy of 76 eV and a half-life of 26 minutes. A pulsed Nd:YAG laser operating at 1064 nm with a pulse energy of 789 mJ and a pulse width of 9 ns was used to generate a uranium plasma. The plasma was captured on a catcher plate and electrons emitted from the catcher plate were accelerated and focused onto a microchannel plate detector. A decay of 26 minutes would suggest the creation of 235mU and the possibility that NEET occurred. However, measurements performed using a variety of uranium targets spanning depleted uranium up to 99.4% enriched uranium did not observe a 26 minute decay. Numerous other decays were observed with half-lives ranging from minutes up to hundreds of minutes. While NEET of 235U was not observed during this experiment, an upper limit for the NEET rate of 235U was determined. In addition, explanations for the con icting results from previous experiments are given. Based on the results of this experiment and the previous experiments looking for NEET of 235U, it is likely that NEET of 235U has never been observed.

  6. 7 CFR 205.208-205.235 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Organic Production and Handling Requirements §§ 205.208-205.235...

  7. Assay Method for 235U in Low-Density Waste

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>235U assay method will provide a semi-quantitative assay for any uranium lumps that might exist in low-density, low-Z material waste boxes within a short count time. These materials will consist of

  8. Monsanto Gives Washington U. $23.5 Million.

    Science.gov (United States)

    Culliton, Barbara J.

    1982-01-01

    Reviews various provisions of a five-year, $23.5-million research agreement between Washington University and the Monsanto Company. The scientific focus of this venture will be on proteins and peptides which modify cellular behavior. (SK)

  9. γ-Determination of 235U Enrichment in Inspection Techniques

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The uranium enrichment analysis method was studied and established for the thick shielding uranium samples. The analysis errors are less than 5% at the conditions of 1-3 cm iron shielding for 235U

  10. Measurement of the^ 235U(n,n')^235mU Integral Cross Section in a Pulsed Reactor

    Science.gov (United States)

    Vieira, D. J.; Bond, E. M.; Belier, G.; Meot, V.; Becker, J. A.; Macri, R. A.; Authier, N.; Hyneck, D.; Jacquet, X.; Jansen, Y.; Legrendre, J.

    2009-10-01

    We will present the integral measurement of the neutron inelastic cross section of ^235U leading to the 26-minute, E*=76.5 eV isomer state. Small samples (5-20 microgm) of isotope-enriched ^235U were activated in the central cavity of the CALIBAN pulsed reactor at Valduc where a nearly pure fission neutron spectrum is produced with a typical fluence of 3x10^14 n/cm^2. After 30 minutes the samples were removed from the reactor and counted in an electrostatic-deflecting electron spectrometer that was optimized for the detection of ^235mU conversion electrons. From the decay curve analysis of the data, the 26-minute ^235mU component was extracted. Preliminary results will be given and compared to gamma-cascade calculations assuming complete K-mixing or with no K-mixing.

  11. Should we ignore U-235 series contribution to dose?

    Science.gov (United States)

    Beaugelin-Seiller, Karine; Goulet, Richard; Mihok, Steve; Beresford, Nicholas A

    2016-01-01

    Environmental Risk Assessment (ERA) methodology for radioactive substances is an important regulatory tool for assessing the safety of licensed nuclear facilities for wildlife, and the environment as a whole. ERAs are therefore expected to be both fit for purpose and conservative. When uranium isotopes are assessed, there are many radioactive decay products which could be considered. However, risk assessors usually assume (235)U and its daughters contribute negligibly to radiological dose. The validity of this assumption has not been tested: what might the (235)U family contribution be and how does the estimate depend on the assumptions applied? In this paper we address this question by considering aquatic wildlife in Canadian lakes exposed to historic uranium mining practices. A full theoretical approach was used, in parallel to a more realistic assessment based on measurements of several elements of the U decay chains. The (235)U family contribution varied between about 4% and 75% of the total dose rate depending on the assumptions of the equilibrium state of the decay chains. Hence, ignoring the (235)U series will not result in conservative dose assessments for wildlife. These arguments provide a strong case for more in situ measurements of the important members of the (235)U chain and for its consideration in dose assessments.

  12. 48 CFR 235.006-70 - Manufacturing Technology Program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Manufacturing Technology... CONTRACTING 235.006-70 Manufacturing Technology Program. In accordance with 10 U.S.C. 2521(d), for acquisitions under the Manufacturing Technology Program— (a) Award all contracts using competitive...

  13. 48 CFR 2052.235-70 - Publication of research results.

    Science.gov (United States)

    2010-10-01

    ... publication in refereed scientific and engineering journals or dissemination to the public of any information... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Publication of research....235-70 Publication of research results. As prescribed in 2035.70(a)(1), the contracting officer...

  14. Phenotype abnormality: 235 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 235 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u1ria224u741i decreased speed... in organ named whole plant during process named growth ... whole plant ... decreased speed ... growth ...

  15. 7 CFR 235.5 - Payments to States.

    Science.gov (United States)

    2010-01-01

    ... Status Report, from the total amount of SAE funds made available for that fiscal year (i.e., the formula... payment. FNS will specify the terms and conditions of the State agency's annual grant of SAE funds in...) and/or § 235.6(c) of this part. The amount of SAE funds made available for payment to a State...

  16. Overview of recent U235 neutron cross section evaluation work

    Energy Technology Data Exchange (ETDEWEB)

    Lubitz, C. [Lockheed Martin Corp., Schenectady, NY (United States)

    1998-10-01

    This report is an overview (through 1997) of the U235 neutron cross section evaluation work at Oak Ridge National Laboratory (ORNL), AEA Technology (Harwell) and Lockheed Martin Corp.-Schenectady (LMS), which has influenced, or appeared in, ENDF/B-VI through Release 5. The discussion is restricted to the thermal and resolved resonance regions, apart from some questions about the unresolved region which still need investigation. The important role which benchmark testing has played will be touched on.

  17. Building 235-F Goldsim Fate And Transport Model

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, G. A.; Phifer, M. A.

    2012-09-14

    Savannah River National Laboratory (SRNL) personnel, at the request of Area Completion Projects (ACP), evaluated In-Situ Disposal (ISD) alternatives that are under consideration for deactivation and decommissioning (D&D) of Building 235-F and the Building 294-2F Sand Filter. SRNL personnel developed and used a GoldSim fate and transport model, which is consistent with Musall 2012, to evaluate relative to groundwater protection, ISD alternatives that involve either source removal and/or the grouting of portions or all of 235-F. This evaluation was conducted through the development and use of a Building 235-F GoldSim fate and transport model. The model simulates contaminant release from four 235-F process areas and the 294-2F Sand Filter. In addition, it simulates the fate and transport through the vadose zone, the Upper Three Runs (UTR) aquifer, and the Upper Three Runs (UTR) creek. The model is designed as a stochastic model, and as such it can provide both deterministic and stochastic (probabilistic) results. The results show that the median radium activity concentrations exceed the 5 ?Ci/L radium MCL at the edge of the building for all ISD alternatives after 10,000 years, except those with a sufficient amount of inventory removed. A very interesting result was that grouting was shown to basically have minimal effect on the radium activity concentration. During the first 1,000 years grouting may have some small positive benefit relative to radium, however after that it may have a slightly deleterious effect. The Pb-210 results, relative to its 0.06 ?Ci/L PRG, are essentially identical to the radium results, but the Pb-210 results exhibit a lesser degree of exceedance. In summary, some level of inventory removal will be required to ensure that groundwater standards are met.

  18. 24 CFR 990.235 - PHAs that will experience a subsidy increase.

    Science.gov (United States)

    2010-04-01

    ... increase. 990.235 Section 990.235 Housing and Urban Development Regulations Relating to Housing and Urban... § 990.235 PHAs that will experience a subsidy increase. (a) For PHAs that will experience a gain in their operating subsidy, as determined in § 990.225, such increases will have a limit of 50 percent of...

  19. 48 CFR 53.235 - Research and Development Contracting (SF 298).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Research and Development Contracting (SF 298). 53.235 Section 53.235 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.235 Research and Development...

  20. 48 CFR 235.070-1 - Indemnification under research and development contracts.

    Science.gov (United States)

    2010-10-01

    ... research and development contracts. 235.070-1 Section 235.070-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 235.070-1 Indemnification under research and development contracts. (a...

  1. 24 CFR 235.331 - Increased maximum mortgage amount for physically handicapped persons.

    Science.gov (United States)

    2010-04-01

    ... for physically handicapped persons. 235.331 Section 235.331 Housing and Urban Development Regulations... maximum mortgage amount for physically handicapped persons. If the mortgage relates to a dwelling unit to be occupied by a handicapped person as defined in § 235.5(c)(2), the otherwise applicable...

  2. Preliminary Study on the Determination of ~(235)U and ~(239)Pu Using Delayed Neutron Counting Method

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The preliminary study on the fast measurements of 235U and 239Pu in samples containing 235U, 239Pu and 235U-239Pu mixture using delayed neutron counting method is introduced. All samples were irradiated for 30 s using the 30 kW Miniature Neutron

  3. 22 CFR 23.5 - Claims for settlement by Department of State or General Accounting Office.

    Science.gov (United States)

    2010-04-01

    ... General Accounting Office. 23.5 Section 23.5 Foreign Relations DEPARTMENT OF STATE FEES AND FUNDS FINANCE AND ACCOUNTING § 23.5 Claims for settlement by Department of State or General Accounting Office. Claims for settlement by the Department of State or by the General Accounting Office shall be...

  4. 235对夫妻HIV/AIDS感染情况调查%HIV/AIDS infection investigation of 235 couples

    Institute of Scientific and Technical Information of China (English)

    潘新莲; 柳智豪; 陈坚; 农守玩; 农慧桃

    2010-01-01

    目的 了解艾滋病病毒(HIV)夫妻感染情况的流行病学特征,为预防该人群HIV感染和传播提供依据.方法 利用百色市2005~2009年艾滋病自愿咨询检测资料,对其中已婚感染HIV的夫或妻进行流行病学统计分析.结果 235对夫妻(470例)双方都感染HIV的90对,阳性率38.30%(90/235).其中,男方阳性率75.74%(178/235),女方阳性率62.98%(148/235).感染HIV的高危行为史,男方主要有婚外无保护的多性伴行为,比例为87.64%(156/178),女方主要是男方携带IHV不知情.夫妻性生活未采取保护措施被感染的比例为47.97%(71/148).发现HIV感染主要原因,男方出现机会性感染住院治疗筛查HIV阳性转介确认,比例为69.10%(123/178),女方配偶阳性通知检查发现感染比例为31.08%(46/148).职业分布主要是农民工和经商比例54.29%(177/326)和18.10%(59/326).结论 婚外多性伴是夫妻感染和传播HIV的主要方式,农民工和经商职业人口流动大,须加强该人群的高危行为干预措施,减少感染来源和家庭内的传播.

  5. Measurement of 235U(n,n'γ) and 235U(n,2nγ) reaction cross sections

    Science.gov (United States)

    Kerveno, M.; Thiry, J. C.; Bacquias, A.; Borcea, C.; Dessagne, P.; Drohé, J. C.; Goriely, S.; Hilaire, S.; Jericha, E.; Karam, H.; Negret, A.; Pavlik, A.; Plompen, A. J. M.; Romain, P.; Rouki, C.; Rudolf, G.; Stanoiu, M.

    2013-02-01

    The design of generation IV nuclear reactors and the studies of new fuel cycles require knowledge of the cross sections of various nuclear reactions. Our research is focused on (n,xnγ) reactions occurring in these new reactors. The aim is to measure unknown cross sections and to reduce the uncertainty on present data for reactions and isotopes of interest for transmutation or advanced reactors. The present work studies the 235U(n,n'γ) and 235U(n,2nγ) reactions in the fast neutron energy domain (up to 20 MeV). The experiments were performed with the Geel electron linear accelerator GELINA, which delivers a pulsed white neutron beam. The time characteristics enable measuring neutron energies with the time-of-flight (TOF) technique. The neutron induced reactions [in this case inelastic scattering and (n,2n) reactions] are identified by on-line prompt γ spectroscopy with an experimental setup including four high-purity germanium (HPGe) detectors. A fission ionization chamber is used to monitor the incident neutron flux. The experimental setup and analysis methods are presented and the model calculations performed with the TALYS-1.2 code are discussed.

  6. Calibration of a modified Sierra Model 235 slotted cascade impactor

    Energy Technology Data Exchange (ETDEWEB)

    Knuth, R.H.

    1979-07-01

    For measurements of ore dust in uranium concentrating mills, a Sierra Model 235 slotted cascade impactor was calibrated at a flow rate of .21 m/sup 3//min, using solid monodisperse particles and an impaction surface of Whatman No. 41 filter paper soaked in mineral oil. The reduction from the impactor's design flow rate of 1.13 m/sup 3//min (40 cfm) to 0.21 m/sup 3//min (7.5 cfm) increased the stage cut-off diameters by an average factor of 2.3, a necessary adjustment because of the anticipated large particle sizes of ore dust. The underestimation of mass median diameters, often caused by the rebound and reentrainment of solid particles from dry impaction surfaces, was virtually eliminated by using the oiled Whatman No. 41 impaction surface. Observations of satisfactory performance in the laboratory were verified by tests of the impactor in ore mills.

  7. The M235T polymorphism of the angiotensinogen gene in women with polycystic ovary syndrome.

    Science.gov (United States)

    Zulian, Elisa; Sartorato, Paola; Schiavi, Francesca; Moghetti, Paolo; Castello, Roberto; Mantero, Franco; Opocher, Giuseppe; Scaroni, Carla

    2005-11-01

    To explore the relationship between variation in AGT M235T gene and the development of the polycystic ovary syndrome (PCOS) and its sequelae, in the present study we evaluated AGT polymorphism M235T in women with PCOS and in a control group. Moreover, to detect any relationship between AGT M235T variation and intermediate and quantitative traits relevant to the pathogenesis of cardiovascular disease and PCOS, we looked for genotype-dependent differences within the subjects with PCOS.

  8. Dispersion of the Neutron Emission in U{sup 235} Fission

    Science.gov (United States)

    Feynman, R. P.; de Hoffmann, F.; Serber, R.

    1955-01-01

    Equations are developed which allow the calculation of the average number of neutrons per U{sup235} fission from experimental measurements. Experimental methods are described, the results of which give a value of (7.8 + 0.6){sup ½} neutrons per U{sup 235} thermal fission.

  9. 45 CFR 235.60 - Federal financial participation (FFP) for State and local training.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Federal financial participation (FFP) for State... participation (FFP) for State and local training. Sections 235.61 through 235.66 contain (a) State plan requirements for training programs and (b) conditions for Federal financial participation (FFP) for...

  10. 48 CFR 235.015-70 - Special use allowances for research facilities acquired by educational institutions.

    Science.gov (United States)

    2010-10-01

    ... research facilities acquired by educational institutions. 235.015-70 Section 235.015-70 Federal Acquisition... acquired by educational institutions. (a) Definitions. As used in this subsection— (1) Research facility... 31.3. (b) Policy. (1) Educational institutions are to furnish the facilities necessary to...

  11. 48 CFR 3052.235-70 - Dissemination of information-educational institutions.

    Science.gov (United States)

    2010-10-01

    ... information-educational institutions. 3052.235-70 Section 3052.235-70 Federal Acquisition Regulations System... information—educational institutions. As prescribed in (HSAR) 48 CFR 3035.7000, insert the following clause: Dissemination of Information—Educational Institutions (DEC 2003) (a) The Department of Homeland Security...

  12. 40 CFR 52.235 - Control strategy for ozone: Oxides of nitrogen.

    Science.gov (United States)

    2010-07-01

    ... nitrogen. 52.235 Section 52.235 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... for ozone: Oxides of nitrogen. EPA is approving an exemption request submitted by the Monterey Bay... the area from implementing the oxides of nitrogen (NOX) requirements for reasonably available...

  13. Use of integral experiments for the assessment of a new 235U IRSN-CEA evaluation

    Directory of Open Access Journals (Sweden)

    Ichou Raphaëlle

    2017-01-01

    Full Text Available The Working Party on International Nuclear Data Evaluation Co-operation (WPEC subgroup 29 (SG 29 was established to investigate an issue with the 235U capture cross-section in the energy range from 0.1 to 2.25 keV, due to a possible overestimation of 10% or more. To improve the 235U capture crosssection, a new 235U evaluation has been proposed by the Institut de Radioprotection et de Sûreté Nucléaire (IRSN and the CEA, mainly based on new time-of-flight 235U capture cross-section measurements and recent fission cross-section measurements performed at the n_TOF facility from CERN. IRSN and CEA Cadarache were in charge of the thermal to 2.25 keV energy range, whereas the CEA DIF was responsible of the high energy region. Integral experiments showing a strong 235U sensitivity are used to assess the new evaluation, using Monte-Carlo methods. The keff calculations were performed with the 5.D.1 beta version of the MORET 5 code, using the JEFF-3.2 library and the new 235U evaluation, as well as the JEFF-3.3T1 library in which the new 235U has been included. The benchmark selection allowed highlighting a significant improvement on keff due to the new 235U evaluation. The results of this data testing are presented here.

  14. Discrete deexcitations in 235U from Nuclear Resonance Fluorescence

    Science.gov (United States)

    Kwan, E.; Howell, C. R.; Raut, R.; Rusev, G.; Tonchev, A. P.; Tornow, W.; Adekola, A. S.; Hammond, S. L.; Karwowski, H. J.; Pedroni, R.; Kelley, J. H.

    2010-11-01

    Systematics of the even-even rare-earth nuclei suggest a concentration of M1 excitations peaking around 3 MeV with a ∑B(M1) strength of ˜3μN^2. In addition, a linear dependence on the square of the ground-state deformation was observed in the systematics of the ∑B(M1) strengths. The actinide region is interesting for investigation of the ``scissors'' mode of M1 excitations because it has neutron-rich nuclei with large deformations. Evidence of M1 resonances concentrated around 2.0-2.5 MeV were found in ^238U & ^232Th. A research program has been initiated at TUNL to measure dipole transitions in the actinide using HIγS. Nearly monoenergic & circular polarized γ-ray beams below 3.0 MeV was used to measure transitions in ^235U. More than 20 transitions were observed. The integrated cross sections, B(M1) strengths & branching transitions intensities will be presented and compared with previous measurements.

  15. 41 CFR 102-37.235 - What type of information must a SASP provide when requesting surplus property for cannibalization?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What type of information must a SASP provide when requesting surplus property for cannibalization? 102-37.235 Section 102-37.235... Surplus Property (SASP) Justifying Special Transfer Requests § 102-37.235 What type of information must...

  16. Phosphorylation of NS5A Serine-235 is essential to hepatitis C virus RNA replication and normal replication compartment formation

    Energy Technology Data Exchange (ETDEWEB)

    Eyre, Nicholas S., E-mail: nicholas.eyre@adelaide.edu.au [School of Biological Sciences and Research Centre for Infectious Diseases, University of Adelaide, Adelaide (Australia); Centre for Cancer Biology, SA Pathology, Adelaide (Australia); Hampton-Smith, Rachel J.; Aloia, Amanda L. [School of Biological Sciences and Research Centre for Infectious Diseases, University of Adelaide, Adelaide (Australia); Centre for Cancer Biology, SA Pathology, Adelaide (Australia); Eddes, James S. [Adelaide Proteomics Centre, School of Biological Sciences, University of Adelaide, Adelaide (Australia); Simpson, Kaylene J. [Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, East Melbourne (Australia); The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville (Australia); Hoffmann, Peter [Adelaide Proteomics Centre, School of Biological Sciences, University of Adelaide, Adelaide (Australia); Institute for Photonics and Advanced Sensing (IPAS), University of Adelaide, Adelaide (Australia); Beard, Michael R. [School of Biological Sciences and Research Centre for Infectious Diseases, University of Adelaide, Adelaide (Australia); Centre for Cancer Biology, SA Pathology, Adelaide (Australia)

    2016-04-15

    Hepatitis C virus (HCV) NS5A protein is essential for HCV RNA replication and virus assembly. Here we report the identification of NS5A phosphorylation sites Ser-222, Ser-235 and Thr-348 during an infectious HCV replication cycle and demonstrate that Ser-235 phosphorylation is essential for HCV RNA replication. Confocal microscopy revealed that both phosphoablatant (S235A) and phosphomimetic (S235D) mutants redistribute NS5A to large juxta-nuclear foci that display altered colocalization with known replication complex components. Using electron microscopy (EM) we found that S235D alters virus-induced membrane rearrangements while EM using ‘APEX2’-tagged viruses demonstrated S235D-mediated enrichment of NS5A in irregular membranous foci. Finally, using a customized siRNA screen of candidate NS5A kinases and subsequent analysis using a phospho-specific antibody, we show that phosphatidylinositol-4 kinase III alpha (PI4KIIIα) is important for Ser-235 phosphorylation. We conclude that Ser-235 phosphorylation of NS5A is essential for HCV RNA replication and normal replication complex formation and is regulated by PI4KIIIα. - Highlights: • NS5A residues Ser-222, Ser-235 and Thr-348 are phosphorylated during HCV infection. • Phosphorylation of Ser-235 is essential to HCV RNA replication. • Mutation of Ser-235 alters replication compartment localization and morphology. • Phosphatidylinositol-4 kinase III alpha is important for Ser-235 phosphorylation.

  17. Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.

    Directory of Open Access Journals (Sweden)

    Solabomi A Ogun

    2011-02-01

    Full Text Available Plasmodium yoelii YM asexual blood stage parasites express multiple members of the py235 gene family, part of the super-family of genes including those coding for Plasmodium vivax reticulocyte binding proteins and Plasmodium falciparum RH proteins. We previously identified a Py235 erythrocyte binding protein (Py235EBP-1, encoded by the PY01365 gene that is recognized by protective mAb 25.77. Proteins recognized by a second protective mAb 25.37 have been identified by mass spectrometry and are encoded by two genes, PY01185 and PY05995/PY03534. We deleted the PY01365 gene and examined the phenotype. The expression of the members of the py235 family in both the WT and gene deletion parasites was measured by quantitative RT-PCR and RNA-Seq. py235ebp-1 expression was undetectable in the knockout parasite, but transcription of other members of the family was essentially unaffected. The knockout parasites continued to react with mAb 25.77; and the 25.77-binding proteins in these parasites were the PY01185 and PY05995/PY03534 products. The PY01185 product was also identified as erythrocyte binding. There was no clear change in erythrocyte invasion profile suggesting that the PY01185 gene product (designated PY235EBP-2 is able to fulfill the role of EBP-1 by serving as an invasion ligand although the molecular details of its interaction with erythrocytes have not been examined. The PY01365, PY01185, and PY05995/PY03534 genes are part of a distinct subset of the py235 family. In P. falciparum, the RH protein genes are under epigenetic control and expression correlates with binding to distinct erythrocyte receptors and specific invasion pathways, whereas in P. yoelii YM all the genes are expressed and deletion of one does not result in upregulation of another. We propose that simultaneous expression of multiple Py235 ligands enables invasion of a wide range of host erythrocytes even in the presence of antibodies to one or more of the proteins and that this

  18. Targeted disruption of py235ebp-1: Invasion of erythrocytes by Plasmodium yoelii using an alternative py235 erythrocyte binding protein

    KAUST Repository

    Ogun, Solabomi A.

    2011-02-17

    Plasmodium yoelii YM asexual blood stage parasites express multiple members of the py235 gene family, part of the super-family of genes including those coding for Plasmodium vivax reticulocyte binding proteins and Plasmodium falciparum RH proteins. We previously identified a Py235 erythrocyte binding protein (Py235EBP-1, encoded by the PY01365 gene) that is recognized by protective mAb 25.77. Proteins recognized by a second protective mAb 25.37 have been identified by mass spectrometry and are encoded by two genes, PY01185 and PY05995/PY03534. We deleted the PY01365 gene and examined the phenotype. The expression of the members of the py235 family in both the WT and gene deletion parasites was measured by quantitative RT-PCR and RNA-Seq. py235ebp-1 expression was undetectable in the knockout parasite, but transcription of other members of the family was essentially unaffected. The knockout parasites continued to react with mAb 25.77; and the 25.77-binding proteins in these parasites were the PY01185 and PY05995/PY03534 products. The PY01185 product was also identified as erythrocyte binding. There was no clear change in erythrocyte invasion profile suggesting that the PY01185 gene product (designated PY235EBP-2) is able to fulfill the role of EBP-1 by serving as an invasion ligand although the molecular details of its interaction with erythrocytes have not been examined. The PY01365, PY01185, and PY05995/PY03534 genes are part of a distinct subset of the py235 family. In P. falciparum, the RH protein genes are under epigenetic control and expression correlates with binding to distinct erythrocyte receptors and specific invasion pathways, whereas in P. yoelii YM all the genes are expressed and deletion of one does not result in upregulation of another. We propose that simultaneous expression of multiple Py235 ligands enables invasion of a wide range of host erythrocytes even in the presence of antibodies to one or more of the proteins and that this functional

  19. Targeted disruption of py235ebp-1: invasion of erythrocytes by Plasmodium yoelii using an alternative Py235 erythrocyte binding protein.

    Science.gov (United States)

    Ogun, Solabomi A; Tewari, Rita; Otto, Thomas D; Howell, Steven A; Knuepfer, Ellen; Cunningham, Deirdre A; Xu, Zhengyao; Pain, Arnab; Holder, Anthony A

    2011-02-01

    Plasmodium yoelii YM asexual blood stage parasites express multiple members of the py235 gene family, part of the super-family of genes including those coding for Plasmodium vivax reticulocyte binding proteins and Plasmodium falciparum RH proteins. We previously identified a Py235 erythrocyte binding protein (Py235EBP-1, encoded by the PY01365 gene) that is recognized by protective mAb 25.77. Proteins recognized by a second protective mAb 25.37 have been identified by mass spectrometry and are encoded by two genes, PY01185 and PY05995/PY03534. We deleted the PY01365 gene and examined the phenotype. The expression of the members of the py235 family in both the WT and gene deletion parasites was measured by quantitative RT-PCR and RNA-Seq. py235ebp-1 expression was undetectable in the knockout parasite, but transcription of other members of the family was essentially unaffected. The knockout parasites continued to react with mAb 25.77; and the 25.77-binding proteins in these parasites were the PY01185 and PY05995/PY03534 products. The PY01185 product was also identified as erythrocyte binding. There was no clear change in erythrocyte invasion profile suggesting that the PY01185 gene product (designated PY235EBP-2) is able to fulfill the role of EBP-1 by serving as an invasion ligand although the molecular details of its interaction with erythrocytes have not been examined. The PY01365, PY01185, and PY05995/PY03534 genes are part of a distinct subset of the py235 family. In P. falciparum, the RH protein genes are under epigenetic control and expression correlates with binding to distinct erythrocyte receptors and specific invasion pathways, whereas in P. yoelii YM all the genes are expressed and deletion of one does not result in upregulation of another. We propose that simultaneous expression of multiple Py235 ligands enables invasion of a wide range of host erythrocytes even in the presence of antibodies to one or more of the proteins and that this functional

  20. 5 CFR 591.235 - When do COLA and post differential payments begin?

    Science.gov (United States)

    2010-01-01

    ... SERVICE REGULATIONS ALLOWANCES AND DIFFERENTIALS Cost-of-Living Allowance and Post Differential-Nonforeign Areas Program Administration § 591.235 When do COLA and post differential payments begin? (a)...

  1. Precise determination of the 235U reactor antineutrino cross section per fission

    Science.gov (United States)

    Giunti, C.

    2017-01-01

    We investigate which among the reactor antineutrino fluxes from the decays of the fission products of 235U, 238U, 239Pu, and 241Pu may be responsible for the reactor antineutrino anomaly if the anomaly is due to a miscalculation of the antineutrino fluxes. We find that it is very likely that at least the calculation of the 235U flux must be revised. From the fit of the data we obtain the precise determination σ235 = (6.33 ± 0.08) ×10-43cm2 /fission of the 235U cross section per fission, which is more precise than the calculated value and differs from it by 2.2σ. The cross sections per fission of the other fluxes have large uncertainties and in practice their values are undetermined by the fit.

  2. Determination of 235U/238U Ratio on Urine by ICP-MS

    Energy Technology Data Exchange (ETDEWEB)

    Collins, L; Gobaleza, A; Langston, R; Radev, R; Than, C; Wong, C; Wood-Zika, A

    2011-10-19

    LLNL Internal Dosimetry Program - The new procedure satisfies the requirement to determine {sup 235}U/{sup 238}U ratio in bioassay urine samples. MDA - The L{sub C} and MDA{sub 95} for {sup 235}U are well below the required detection limit of 0.00035 {mu}g/L. Turn around time - Analysis of 10 samples plus 2 QCs can be completed in one work day (8 hours).

  3. N235萃取某富铀浸出液中铀的研究%Extraction of Uranium from Rich Uranium Leaching Solution by N235

    Institute of Scientific and Technical Information of China (English)

    张鑫; 朱姝; 周青生; 鄢飞燕

    2015-01-01

    The extraction of U (Ⅵ) from rich uranium leaching solution by N235, mixed alcohols and sulfonated kerosene was studied. The influence of several variables on the extraction rate of uranium, including the N235 volume fraction, phase ratio (A/O) and equilibrium time was investigated. The results show that the extraction rate is 99.92% when the volume ratio of N235, mixed alcohols and sulfonated kerosene is 10:4:86, phase ratio is 1:2, and extracting time is 2 min. The uranium in organic phase was stripping by ammonium carbonate, and stripping rate is 99.93%. Also, the ammonium uranyl tricarbonate product was in line with national standard.%以N235为萃取剂、混合醇为添加剂、磺化煤油为稀释剂从某富铀浸出液中萃取六价铀。考察了萃取剂用量、相比、平衡时间等因素对萃取率的影响,研究结果表明:当N235:混合醇:磺化煤油体积比为10:4:86,相比为1:2,萃取时间为2 min,铀的萃取率为99.92%;用碳酸铵溶液进行反萃取试验,反萃取率为99.93%,产品三碳酸铀酰铵符合国家标准要求。

  4. The Application of 238U/235U as a Redox-Proxy for Past Ocean Chemistry

    Science.gov (United States)

    Andersen, M. B.; Westermann, S.; Bahniuk, A.; Vasconcelos, C.; McKenzie, J. A.; Föllmi, K. B.; Vance, D.

    2014-12-01

    The recent discovery of significant variation in 238U/235U caused by redox change at the surface Earth has led to its use to extract information on the oxygenation state of ancient oceans from marine sediments [e.g. 1]. Recent studies have focused on improving the understanding of the 238U/235U signature in modern marine carbonates [2] and black shales [3] to improve the robustness of this tracer. To further advance its use we have focused on improving our understanding of 238U/235U systematics in modern dolomite, another commonly occurring rock-type in the geological record, before turning to 238U/235U signatures in ancient sediments. The measured dolomite samples, precipitated in modern environments of coastal hypersaline lagoons in Brazil, all exhibit 238U/235U values that deviate from the seawater composition [3]. Observed values are both lighter (ca. 130 ppm; as also observed in dolomite from tidal-ponds on Bahamas [2]) and heavier (50-180 ppm). These distinct 238U/235U values for different dolomite-precipitates likely attest to the particular formation style, as well as early diagenetic processes. We use such modern settings to discuss the utility of 238U/235U in ancient sediments, the singularity of any observed 238U/235U signal, its relation to global ocean chemistry and potential diagenetic overprinting. These constraints are then used to evaluate a well-preserved marine carbonate section [4] and published black shale 238U/235U data [1], both deposited during the Oceanic Anoxic Event 2 (93 Ma). We discuss the capabilities of both the carbonate and black shale section for retaining information on the 238U/235U composition in the ocean during OAE 2. [1] Montoya-Pino et al. (2010) Geology, 38, 315-318 [2] Romaniello et al. (2013) 362, 305-316 [3] Andersen et al. (2014) EPSL, 400, 184-194 [4] Westermann et al. (2010) Cret. Res., 31, 500-514

  5. Relative {sup 235}U(n,{gamma}) and (n,f) cross sections from {sup 235}U(d,p{gamma}) and (d,pf)

    Energy Technology Data Exchange (ETDEWEB)

    Allmond, J.M.; Bernstein, L.A.; Beausang, C.W.; Phair, L.; Bleuel, D.L.; Burke, J.T.; Escher, J.E.; Evans, K.E.; Goldblum, B.L.; Hatarik,, R.; Jeppesen, H.B.; Rasmussen, J.O.

    2009-01-01

    The internal surrogate ratio method allows for the determination of an unknown cross section, such as (n,{gamma}), relative to a better-known cross section, such as (n,f), by measuring the relative exit-channel probabilities of a surrogate reaction that proceeds through the same compound nucleus. The validity of the internal surrogate ratio method is tested by comparing the relative gamma and fission exit-channel probabilities of a {sup 236}U* compound nucleus, formed in the {sup 235}U(d,p) reaction, to the known {sup 235}U(n,{gamma}) and (n,f) cross sections. A model-independent method for measuring the gamma-channel yield is presented and used.

  6. Fine structure at the diffusion welded interface of Fe3Al/Q235 dissimilar materials

    Indian Academy of Sciences (India)

    Wang Juan; Li Yajiang; Wu Huiqiang

    2001-12-01

    The interface of Fe3Al/Q235 dissimilar materials joint, which was made by vacuum diffusion welding, combines excellently. There are Fe3Al, FeAl phases and -Fe (Al) solid solution at the interface of Fe3Al/Q235. Aluminum content decreases from 28% to 1.5% and corresponding phase changes from Fe3Al with DO3 type body centred cubic (bcc) structure to -Fe (Al) solid solution with B2 type bcc structure. All phases are present in sub-grain structure level and there is no obvious brittle phases or micro-defects such as pores and cracks at the interface of Fe3Al/Q235 diffusion joint.

  7. Measurements of structural material capture to uranium-235 fission rate ratios in an intermediate spectrum assembly

    Energy Technology Data Exchange (ETDEWEB)

    Azzoni, P.; Benzi, V.; Chiodi, P.L.; Giuliani, C.; Guardini, S.; Marrasi, R.; Salomoni, A.; Tassan, S.

    1980-10-01

    Experimental determinations of capture rates of structural materials used in fast breeder reactors, such as iron, chromium, nickel, and stainless steel, normalized to the /sup 235/U fission rate, were performed. The aim of these experiments was to check structural material multigroup cross-section libraries in the 1- to 100-keV range, where substantial discrepancies among various cross-section evaluations are not yet resolved. The experiments were carried out in an ARGONAUTtype RB-2 reactor, using the Null Reactivity Oscillation method, on test media composed of quasi-homogeneous loose particle mixtures. Comparisons were carried out with corresponding calculated values, showing a trend of these values to overestimate the measured quantities. These results are not in disagreement with the indications of recent /sup 235/U cross-section measurements as far as the sigma /SUB c/ /sigma /SUB f/ of /sup 235/U is concerned.

  8. A Preliminary Calculation of 235U (n,2n) 234U Cross Sections

    Energy Technology Data Exchange (ETDEWEB)

    Chen, H.; Ross, M.A.; Reffo, G.; White, R.M.; Younes, W.

    1999-11-23

    Preliminary calculations of the total two-neutron emission cross section, {sup 235}U(n,2n) {sup 234}U and the partial two-neutron emission cross sections, {sup 235}U(n, 2n{gamma}) {sup 234}U, are presented. The {sup 235}U(n, 2n{gamma}) {sup 234}U cross sections describe the process of {gamma}-decays in the residual nucleus following the two-neutron emission and were calculated for several {gamma}-transitions between states of the ground-state band of the {sup 234}U nucleus. All three reaction mechanisms, namely, direct, pre-equilibrium and compound, were included. In addition, fission competition as well as {gamma}-cascade were considered in the compound component of the cross section calculations. A comparison with the relevant experimental data obtained from the GEANIE detector at the LANSCE/WNR facility in Los Alamos was also carried out.

  9. DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer.

    Science.gov (United States)

    Ghelardini, C; Galeotti, N; Gualtieri, F; Romanelli, M N; Bucherelli, C; Baldi, E; Bartolini, A

    2002-06-01

    DM235 (sunifiram), a new compound structurally related to piracetam, prevented the amnesia induced by scopolamine (1.5 mg kg(-1) i.p.), after intraperitoneal (0.001-0.1 mg kg(-1)) or oral (0.01-0.1 mg kg(-1)) administration, as shown by a passive avoidance test in mice. The antiamnesic effect of DM235 was comparable to that of well-known nootropic drugs such as piracetam (30-100 mg kg(-1) i.p.), aniracetam (100 mg kg(-1) p.o.) or rolipram (30 mg kg(-1) p.o.). DM235 also prevented mecamylamine (20 mg kg(-1) i.p.)-, baclofen (2 mg kg(-1) i.p.)- and clonidine (0.125 mg kg(-1) i.p.)-induced amnesia in the same test. In the Morris water maze test with rats, scopolamine (0.8 mg kg(-1) i.p.) inhibited the reduction of escape latency in both acquisition and retention/retraining tests. DM235 (0.1 mg kg(-1) i.p.), 20 min before each daily acquisition training, prevented the scopolamine-induced memory impairment. DM235 (1 mg kg(-1) i.p.) also reduced the duration of pentobarbitone-induced hypnosis in mice without modifying the induction time of hypnosis. At the highest effective doses, the investigated compound neither impaired motor coordination (rota-rod test), nor modified spontaneous motility and inspection activity (Animex and hole board tests). These results indicate that DM235, a compound structurally related to piracetam, is a novel nootropic endowed with the capability to prevent cognitive deficits at very low doses. Indeed, its potency is about 1,000 times higher than that of the most active piracetam-like compounds.

  10. SLAC术235例围手术期的护理

    Institute of Scientific and Technical Information of China (English)

    邵咏新; 高小雁

    2010-01-01

    目的:探讨SLAC术围手术期护理措施.方法:对SLAC术235例进行围手术期的护理.结果:SLAC术235例,无一例因护理不当引发的并发症.结论:SLAC术是目前治疗多节段颈椎病较有效的方法,正确有效的围手术期护理是不可缺少的重要环节.

  11. Measurement of 235U Fission Yield Induced by 252Cf Fission Neutron

    Institute of Scientific and Technical Information of China (English)

    YANG; Yi; LIU; Shi-long; JIANG; Wen-gang

    2015-01-01

    We measured fission yields of 235U by 252Cf fission neutrons with the directγray spectrometric method.Square sample foils of 15 mm,abundance of 235U is 90.2%,mass of 0.7gram,covered by pure aluminum foil.After irradiations every sample was measured by HPGe spectrometry for about 2months.Based on 140Ba’s fission yield,we get relative fission yields and the results were shown in Fig.1.

  12. Production and identification of new neutron-deficient isotope 235Am in region of transuranium

    Institute of Scientific and Technical Information of China (English)

    甘再国; 郭俊盛; 刘洪业; 石立军; 杨维凡; 牟万统; 郭天瑞; 方克明; 沈水法; 袁双贵; 张学谦; 秦芝; 马瑞昌; 钟纪泉; 罗亦孝; 王书鸿; 孔登明; 乔际民

    1997-01-01

    A new transuranium neutron-deficient isotope 235Am was produced by 35 MeV proton to bombard the rare radioactive 238Pu target The products were transported and collected by the He-jet system. The Am isotopes were separated and purified by radiochemtstry method and the γ-ray, X-ray and γ-X(γ) coincidence of the samples was measured The synthesis of 235 Am was definitely identified Its measured half-life is (15±5) mom.

  13. 25 CFR 900.235 - What personal conflicts of interest must the standards of conduct regulate?

    Science.gov (United States)

    2010-04-01

    ...-DETERMINATION AND EDUCATION ASSISTANCE ACT Conflicts of Interest § 900.235 What personal conflicts of interest... 25 Indians 2 2010-04-01 2010-04-01 false What personal conflicts of interest must the standards of... of more than nominal value, from a party (other than the Indian tribe) with an interest in the trust...

  14. 50 CFR 23.5 - How are the terms used in these regulations defined?

    Science.gov (United States)

    2010-10-01

    ..., EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS (CONTINUED) CONVENTION ON INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.5 How are the terms used in these... suspected to be in trade or there is demonstrable potential international demand for the species that may...

  15. Verification of 235U mass content in nuclear fuel plates by an absolute method

    Science.gov (United States)

    El-Gammal, W.

    2007-01-01

    Nuclear Safeguards is referred to a verification System by which a State can control all nuclear materials (NM) and nuclear activities under its authority. An effective and efficient Safeguards System must include a system of measurements with capabilities sufficient to verify such NM. Measurements of NM using absolute methods could eliminate the dependency on NM Standards, which are necessary for other relative or semi-absolute methods. In this work, an absolute method has been investigated to verify the 235U mass content in nuclear fuel plates of Material Testing Reactor (MTR) type. The most intense gamma-ray signature at 185.7 keV emitted after α-decay of the 235U nuclei was employed in the method. The measuring system (an HPGe-spectrometer) was mathematically calibrated for efficiency using the general Monte Carlo transport code MCNP-4B. The calibration results and the measured net count rate were used to estimate the 235U mass content in fuel plates at different detector-to-fuel plate distances. Two sets of fuel plates, containing natural and low enriched uranium, were measured at the Fuel Fabrication Facility. Average accuracies for the estimated 235U masses of about 2.62% and 0.3% are obtained for the fuel plates containing natural and low enriched uranium; respectively, with a precision of about 3%.

  16. Calculation of Prompt Fission Neutron Spectra for ~(235)U (n,f)

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The prompt fission neutron spectra for neutron-induced fission of 235U at En<5 MeV are calculated using the nuclear evaporation theory with a semi-empirical model, in which the non-constant temperature and the constant temperature related to the Fermi gas model

  17. 48 CFR 235.017 - Federally Funded Research and Development Centers.

    Science.gov (United States)

    2010-10-01

    ... DEVELOPMENT CONTRACTING 235.017 Federally Funded Research and Development Centers. (a) Policy. (2) No DoD... Funded Research and Development Center (FFRDC) if a member of its board of directors or trustees... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Federally Funded Research...

  18. Neutron-fragment angular correlations in /sup 235/U(n/sub th/,f)

    Energy Technology Data Exchange (ETDEWEB)

    Franklyn, C.B.

    1986-01-01

    Neutron-fragment angular correlations in /sup 235/U(n/sub th/,f) as a function of neutron energy and fragment mass are presented. The results obtained in this experiment, together with data for neutron-neutron angular correlations, are compared with a Monte Carlo simulation of the fission process incorporating both a scission neutron component and an anisotropic neutron emission component.

  19. 77 FR 55455 - Foreign-Trade Zone 235-Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence...

    Science.gov (United States)

    2012-09-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 235--Lakewood, NJ, Authorization of Production Activity, Cosmetic Essence Innovations, LLC, (Fragrance Bottling), Holmdel, NJ Cosmetic Essence Innovations, LLC...

  20. Relationship of blood pressure variability and angiotensinogen T235M polymorphism with Binswanger’s disease

    Institute of Scientific and Technical Information of China (English)

    位慧芳

    2013-01-01

    Objective To detect the relationship of blood pressure variability(BPV) and angiotensinogen(AGT) T235M polymorphism with Binswanger’s disease(BD). Methods Totally 122 cases with BD and 108 cases with essential hypertension had been enrolled. Ambulatory blood pressure monitoring was used to get the data

  1. Effect of Additional Sulfide and Thiosulfate on Corrosion of Q235 Carbon Steel in Alkaline Solutions

    Directory of Open Access Journals (Sweden)

    Bian Li Quan

    2016-01-01

    Full Text Available This paper investigated the effect of additional sulfide and thiosulfate on Q235 carbon steel corrosion in alkaline solutions. Weight loss method, scanning electron microscopy (SEM equipped with EDS, X-ray photoelectron spectroscopy (XPS, and electrochemical measurements were used in this study to show the corrosion behavior and electrochemistry of Q235 carbon steel. Results indicate that the synergistic corrosion rate of Q235 carbon steel in alkaline solution containing sulfide and thiosulfate is larger than that of sulfide and thiosulfate alone, which could be due to redox reaction of sulfide and thiosulfate. The surface cracks and pitting characteristics of the specimens after corrosion were carefully examined and the corrosion products film is flake grains and defective. The main corrosion products of specimen induced by S2− and S2O32- are FeS, FeS2, Fe3O4, and FeOOH. The present study shows that the corrosion mechanism of S2− and S2O32- is different for the corrosion of Q235 carbon steel.

  2. 28 CFR 2.35 - Mandatory release in the absence of parole.

    Science.gov (United States)

    2010-07-01

    ... the offender may be required to serve for violation of parole or mandatory release. (c) A prisoner... RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.35 Mandatory release in the absence of parole. (a) A prisoner shall be mandatorily released by...

  3. 48 CFR 1852.235-73 - Final Scientific and Technical Reports.

    Science.gov (United States)

    2010-10-01

    ... XXXX.” Except for articles or papers published in scientific, technical or professional journals, the... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Final Scientific and... Provisions and Clauses 1852.235-73 Final Scientific and Technical Reports. As prescribed in...

  4. Q235钢在不同温度和浓度下氢氟酸中的腐蚀性研究%The Corrosion Research of Q235 Steel in Hydrolfuoric Acid at Different Temperature and Concentration

    Institute of Scientific and Technical Information of China (English)

    李壮; 党晓雨; 梁平

    2014-01-01

    为了研究Q235钢在氢氟酸中的腐蚀性,通过维氏硬度试验、拉伸试验对Q235钢进行了力学性能分析,通过光谱分析仪和金相显微镜对Q235钢进行化学成分分析和组织观察。采用室内浸泡法考察了Q235钢在不同温度和不同浓度下的氢氟酸溶液中的腐蚀性能。结果表明:Q235随着氢氟酸腐蚀溶液温度的升高腐蚀加剧。而在不同浓度下,氢氟酸浓度为30%(体积比)的腐蚀速率最低,在40%氢氟酸中腐蚀速率最高。%In order to study the corrosion of Q235 steel in hydrofluoric acid, The Q235 steel mechanical performance analysis by vickers hardness test and tensile test , and Q235 steel chemical composition analysis and microstructure observation with spectrum analyzer and metallographic microscope. Using indoor soaking method and examined the Q235 steel acid corrosion under different temperatures and concentration of hydrofluoric. The results showed that: Q235 corrosion intensified with the increase of hydrofluoric acid etching solution temperature. And under different concentrations, the corrosion rate is the lowest in Hydrofluoric acid concentration of 30%(volume ratio), and in 40% hydrofluoric acid corrosion rate is the highest.

  5. 40 CFR 1045.235 - What emission testing must I perform for my application for a certificate of conformity?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false What emission testing must I perform for my application for a certificate of conformity? 1045.235 Section 1045.235 Protection of... must I perform for my application for a certificate of conformity? This section describes the...

  6. Transgenic Carrizo expressing 'Candidatus Liberibacter asiaticus' effector P235 displays huanglongbing-like symptom and alters some gene expression

    Science.gov (United States)

    ‘Candidatus Liberibacter asiaticus’ (Las) is the agent causing destructive citrus huanglongbing worldwide. A hypothetical protein (P235) was identified in Las genome prophage region, which encodes a 123aa protein with a molecular weight of 14.19kD. Green fluorescence protein (GFP)-fused with P235 ap...

  7. 48 CFR 1552.235-75 - Access to Toxic Substances Control Act Confidential Business Information (APR 1996).

    Science.gov (United States)

    2010-10-01

    ... Control Act Confidential Business Information (APR 1996). 1552.235-75 Section 1552.235-75 Federal...: Access to Toxic Substances Control Act Confidential Business Information (APR 1996) In order to perform... Control Act (TSCA) confidential business information (CBI). The Contractor and all of its...

  8. Effects of NVP-BEZ235 on the proliferation, migration, apoptosis and autophagy in HT-29 human colorectal adenocarcinoma cells.

    Science.gov (United States)

    Yu, Yang; Yu, Xiaofeng; Ma, Jianxia; Tong, Yili; Yao, Jianfeng

    2016-07-01

    The phosphoinositide 3 kinase (PI3K)/Akt/mammalian target of the rapamycin (mTOR) pathway plays a significant role in colorectal adenocarcinoma. NVP-BEZ235 (dactolisib) is a novel dual inhibitor of PI3K/mTOR. The effects of NVP-BEZ235 in human colorectal adenocarcinoma are still unclear. In the present study, we aimed to explore the proliferation, migration, apoptosis and autophagy in HT-29 human colorectal adenocarcinoma cells. HT-29 human colorectal adenocarcinoma cells were treated with NVP-BEZ235 (0, 0.001, 0.01, 0.1, 1 and 3 µM) for 24 and 48 h, respectively. Cells were also treated with NVP-BEZ235 (0.1 µM), DDP (100, 300 and 1,000 µM), and NVP-BEZ235 (0.1 µM) combined with DDP (100, 300 and 1,000 µM) respectively, and cultured for 24 h after treatment. MTT assay was utilized to evaluate the effects of NVP-BEZ235 alone or NVP-BEZ235 combined with cis-diamminedichloroplatinum (DDP) on proliferation of HT-29 cells. Cell wound-scratch assay was used detect cell migration. In addition, expression of microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B and LC3B) in HT-29 cells was detected by immunofluorescence at 48 h after NVP-BEZ235 (1 µM) treatment. Expression of proteins involved in cell cycle and proliferation (p-Akt, p-mTOR and cyclin D1), apoptosis (cleaved caspase-3), and autophagy (cleaved LC3B and Beclin-1) were detected by western blot analysis. NVP-BEZ235 inhibited the proliferation and migration of HT-29 human colorectal adenocarcinoma cells. NVP-BEZ235 decreased protein expression of p-Akt, p-mTOR and cyclin D1, and increased protein expression of cleaved caspase-3, cleaved LC3B and Beclin-1 as the concentrations and the incubation time of NVP-BEZ235 increased. In addition, NVP-BEZ235 and DDP had synergic effects in inhibiting cell proliferation and migration. The expression of protein involved in apoptosis (cleaved caspase-3) was higher in drug combination group compared to the NVP-BEZ235 single treatment group. NVP-BEZ235

  9. 235例卵巢畸胎瘤临床病理分析%Ovarian teratoma:a clinico-pathological study of 235 cases

    Institute of Scientific and Technical Information of China (English)

    冯立新

    2009-01-01

    目的:探讨卵巢畸胎瘤的临床病理特点.方法: 对235例卵巢畸胎瘤患者的临床病理资料进行分析.结果: 235例卵巢畸胎瘤病例中各个年龄均有发生,以20-40岁多发.其中卵巢成熟性囊性畸胎瘤228例,占97%;卵巢未成熟性畸胎瘤4例,占1.7%;卵巢成熟性囊性畸胎瘤恶变2例,占0.9%;卵巢畸胎瘤伴甲状腺类癌1例,占0.4%.结论:卵巢畸胎瘤绝大多数为良性,应及时手术,以减少并发症的发生,未成熟畸胎瘤及恶变者较少,应结合临床综合治疗.

  10. Study of the origin of elements of the uranium-235 family observed in excess in the vicinity of the experimental nuclear EL4 reactor under dismantling. Lessons got at this day and conclusions; Etude de l'origine des elements de la famille de l'uranium-235 observes en exces dans les environs du reacteur nucleaire experimental EL4 en cours de demantelement. Enseignements retires a ce jour et conclusion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This study resumes the discovery of an excess of actinium 227 found around by EL4 nuclear reactor actually in dismantling. The search for the origin of this excess revealed a real inquiry of investigation during three years. Because a nuclear reactor existed in this area a particular attention will have concerned this region. The doubt became the line of conduct to find the answer to the human or natural origin of this excess. Finally and against any evidence, it appears that the origin of this phenomenon was natural, consequence of the particular local geology. The detail of the different investigations is given: search of a possible correlation with the composition of elevations constituent of lanes, search (and underlining) of new sites in the surroundings of the Rusquec pond and the Plouenez station, study of the atmospheric deposits under winds of the nuclear power plant and in the east direction, search of a possible relationship with the gaseous effluents of the nuclear power plant in the past, historical study of radioactive effluents releases in the fifty last years by the analysis of the sedimentary deposits in the Saint-Herbiot reservoir, search of a possible correlation between the excess of actinium 227 and the nuclear power plant activity; search of a possible correlation with a human activity without any relationship with the nuclear activities, search of a correlation with the underground waters, search of a correlation with the geological context, collect of information on the possible transfers in direction of the food chain, determination of the radiological composition of the underground waters ( not perturbed by human activity), search of the cause of an excess of actinium 227 in the old channel of liquid effluents release of the nuclear power plant. The results are given and discussed. And contrary to all expectations the origin of the excess of actinium 227 is completely natural. (N.C.)

  11. An Analysis of the Tvergaard Parameters at Low Initial Stress Triaxiality for S235JR Steel

    Directory of Open Access Journals (Sweden)

    G. Kossakowski Paweł

    2015-01-01

    Full Text Available This paper discusses the influence of the Tvergaard parameters, qi, which are basic constants of the Gurson-Tvergaard-Needleman (GTN material model, on the numerically simulated load-carrying capacity of tensile elements made of S235JR steel. The elements were considered to be under static tension at low initial stress triaxiality σm/σe = 1/3. Two sets of the Tvergaard parameters qi were analyzed: those typical of structural steels and those dependent on material strength properties. The results showed that the Tvergaard parameters, qi, had influence on the load-carrying capacity of tensile elements at low initial stress triaxiality. They affected the strength curves and the changes in the void volume fractions determined for S235JR steel elements

  12. The 235U Prompt Fission Neutron Spectrum in the BR1 Reactor at SCK•CEN

    Directory of Open Access Journals (Sweden)

    Wagemans Jan

    2016-01-01

    Full Text Available The BR1 research reactor at SCK•CEN has a spherical cavity in the graphite above the reactor core. In this cavity an accurately characterised Maxwellian thermal neutron field is present. Different converters can be loaded in the cavity in order to obtain other types of neutron (and gamma irradiation fields. Inside the so-called MARK III converter a fast 235U(n,f prompt fission neutron field can be obtained. With the support of MCNP calculations, irradiations in MARK III can be directly related to the pure 235U(n,f prompt fission neutron spectrum. For this purpose MARK III spectrum averaged cross sections for the most relevant fluence dosimetry reactions have been determined. A calibration factor for absolute measurements has been determined applying activation dosimetry following ISO/IEC 17025 standards.

  13. Calculation of prompt fission neutron spectra for 235U(n,f)

    Institute of Scientific and Technical Information of China (English)

    CHEN Yong-Jing; JIA Min; TAO Xi; QIAN Jing; LIU Ting-Jin; SHU Neng-Chuan

    2012-01-01

    The prompt fission neutron spectra for the neutron-induced fission of 235U at En < 5 MeV are calculated using nuclear evaporation theory with a semi-empirical model,in which the nonconstant and constant temperatures related to the Fermi gas model are taken into account. The calculated prompt fission neutron spectra reproduce the experimental data well.For the n(thermal)+235U reaction,the average nuclear temperature of the fission fragment,and the probability distribution of the nuclear temperature,are discussed and compared with the Los Alamos model.The energy carried away by γ rays emitted from each fragment is also obtained and the results are in good agreement with the existing experimental data.

  14. Fissile Nuclei Rotation Effect in 235U(n,γf) Process

    Science.gov (United States)

    Danilyan, Gevorg; Granz, Peter; Klenke, Jens; Krakhotin, Vyacheslav; Kuznetsov, Valery; Mezei, Ferenz; Novitsky, Vadim; Pavlov, Valery; Russina, Margarita; Shatalov, Pavel; Wilpert, Thomas

    2009-01-01

    A small shift of an angular distribution of prompt γ-rays relative to the fission axis of 236U* 235U(n,γf) process is presented. This effect has been observed in the experiment at BER-II reactor of BENSC/HMI (Berlin). The sign of the shift depends on the direction of the incident neutron beam polarization. This phenomena can be explained by the rotation of fissile nucleus 236U*, like the effect that has been observed recently at ILL in ternary fission of 235U by cold polarized neutrons. The main surprise of this result is the detection of scission gamma-rays radiated by a fissile nucleus during the time interval of the order of 10-21 s before or after the moment of the neck rupture. Detailed measurements of trigger γ-rays energy dependence are in progress at the neutron beam "MEPHISTO" of FRM-II reactor (Garching).

  15. The 235U Prompt Fission Neutron Spectrum in the BR1 Reactor at SCK•CEN

    Science.gov (United States)

    Wagemans, Jan; Malambu, Edouard; Borms, Luc; Fiorito, Luca

    2016-02-01

    The BR1 research reactor at SCK•CEN has a spherical cavity in the graphite above the reactor core. In this cavity an accurately characterised Maxwellian thermal neutron field is present. Different converters can be loaded in the cavity in order to obtain other types of neutron (and gamma) irradiation fields. Inside the so-called MARK III converter a fast 235U(n,f) prompt fission neutron field can be obtained. With the support of MCNP calculations, irradiations in MARK III can be directly related to the pure 235U(n,f) prompt fission neutron spectrum. For this purpose MARK III spectrum averaged cross sections for the most relevant fluence dosimetry reactions have been determined. A calibration factor for absolute measurements has been determined applying activation dosimetry following ISO/IEC 17025 standards.

  16. Improving Corrosion Resistance of Q235 Steel by Ni-Cr Alloyed Layer

    Institute of Scientific and Technical Information of China (English)

    HUANG Jun; ZHANG Pingze; WU Hongyan; BI Qiang

    2012-01-01

    Ni-Cr alloyed layer was formed on surface of Q235 steel by double glow plasma surface metallurgy to improve the corrosion resistance of substrate.The composition and microstructure of alloyed layer was analyzed by SEM and XRD.Potentiodynamic polarization and electrochemical impedance spectroscopy was applied to evaluate the corrosion resistance of the alloyed layer.The results showed working pressure had a great effect on structure of Ni-Cr alloyed layer,and the dense and smooth alloyed layer was prepared at 50 Pa working pressure.Compared with substrate,Ni-Cr alloyed layer exhibited higher corrosion potential,lower corrosion current density and larger charge transfer resistance,which indicated that Ni-Cr alloyed layer significantly modified the corrosion resistance of Q235 steel.

  17. Simple method for rapid determination of {sup 235}U in depleted or low enrichment uranium samples

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez-Becerril, J.; Fernandez-Valverde, S. [Instituto Nacional de Investigaciones Nucleares, Mexico City (Mexico)

    1995-05-01

    The aim of this study is to report the possibility of using {sup 104}Tc for the rapid quantification of {sup 235}U using both {gamma}-rays 43.53 and 74.67 keV, to choose these standards for a more accurate method. A further objective is to make a comparison with the results obtained from the relation {sup 131}Te/{sup 239}U. (author).

  18. Statistical properties of the S-wave resonances of {sup 235}U

    Energy Technology Data Exchange (ETDEWEB)

    Leal, L.C.; Derrien, H.; Larson, N.M.

    1997-06-01

    The resonance parameters of {sup 235}U in the energy range 0 eV to 2.25 keV were obtained from a generalized least squares analysis of a large set of experimental data using the Reich-Moore formalism in the fitting code SAMMY. The aim of the present paper is to present the statistical properties of the s-wave resonance parameters generated from this study.

  19. A new experimental proposal for {sup 235}U PFNS to answer a fifty years old question

    Energy Technology Data Exchange (ETDEWEB)

    Kornilov, N.; Massey, T.; Grimes, S.; Voinov, A. [Dept. of Physics and Astronomy, Ohio Univ., Athens, OH 45701 (United States)

    2011-07-01

    The Prompt Fission Neutron Spectrum (PFNS) from {sup 235}U(n,f) is very important for various nuclear applications. It has been investigated in different experiments. In spite of {approx}50 years of experimental efforts, a continuing conflict exists at thermal neutron energy. Microscopic experimental PFNS cannot describe macroscopic data. In this report we discuss the current status of this problem and suggest a new experiment, which could possibly resolve this problem. (authors)

  20. Total kinetic energy release in the fast neutron-induced fission of $^{235}$U

    CERN Document Server

    Yanez, R; King, J; Barrett, J S; Fotiades, N; Lee, H Y

    2016-01-01

    We have measured the total kinetic energy (TKE) release for the $^{235}$U(n,f) reaction for $E_{n}$=2-100 MeV using the 2E method with an array of Si PIN diode detectors. The neutron energies were determined by time of flight measurements using the white spectrum neutron beam at the LANSCE facility. To benchmark the TKE measurement, the TKE release for $^{235}$U(n$_{th}$,f) was also measured using a thermal neutron beam from the Oregon State University TRIGA reactor, giving pre-neutron emission $E^*_{TKE}=170.7\\pm0.4$ MeV in good agreement with known values. Our measurements are thus absolute measurements. The TKE in $^{235}$U(n,f) decreases non-linearly from 169.0 MeV to 161.4 MeV for $E_{n}$=2-90 MeV. Comparison of the data with the multi-modal fission model of Brosa indicates the TKE decrease is a consequence of the growth of symmetric fission and the corresponding decrease of asymmetric fission with increasing neutron energy. The average TKE associated with the Brosa superlong, standard I and standard II ...

  1. New signposts of massive star formation in the S235A-B region

    CERN Document Server

    Felli, M; Massi, F; Robberto, M; Cesaroni, Riccardo; Felli, Marcello; Massi, Fabrizio; Robberto, Massimo

    2006-01-01

    We report on new aspects of the star-forming region S235AB revealed through high-resolution observations at radio and mid-infrared wavelengths. Using the Very Large Array, we carried out sensitive observations of S235AB in the cm continuum (6, 3.6, 1.3, and 0.7) and in the 22 GHz water maser line. These were complemented with Spitzer Space Telescope Infrared Array Camera archive data to clarify the correspondence between radio and IR sources. We made also use of newly presented data from the Medicina water maser patrol, started in 1987, to study the variability of the water masers found in the region. S235A is a classical HII region whose structure is now well resolved. To the south, no radio continuum emission is detected either from the compact molecular core or from the jet-like structure observed at 3.3 mm, suggesting emission from dust in both cases. We find two new compact radio continuum sources (VLA-1 and VLA-2) and three separate maser spots. VLA-1 coincides with one of the maser spots and with a pre...

  2. The molecular cloud-H II region complexes associated with SH 90 and SH 235

    Science.gov (United States)

    Lafon, G.; Baudry, A.; de La Noe, J.; Deharveng, L.

    1983-07-01

    The Sharpless regions Sh 90 and Sh 235 are characterized on the basis of monochromatic photographs (at H-alpha, N III, and O III) and H-alpha photographic interferograms made at the Observatoire de Haute-Provence and of molecular-cloud maps (at 110.201 and 89.189 GHz) made at the Observatoire de Bordeaux. Sh 90, at a distance of 2.4 kpc, is found to have an evolved-H II-region shell structure, with ionized gas flowing both away from and toward a neutral molecular cloud with a mass of about 60,000 solar mass which lies partly in front of the H II region. Sh 235, at 1.6 kpc, has two extended 100,000-300,000-solar-mass neutral clouds which partly overlap. The northern cloud, identified at -20 km/s, is related to the optical nebula; the southern cloud (at -17 km/s) contains three compact H II regions (A, B, and C) and exhibits recent star-formation processes. The 'champagne' model of H II regions proposed by Tenorio-Tagle (1979) is considered applicable to Sh 90 and to Sh 235C.

  3. Molecular jet emission and a spectroscopic survey of S235AB

    CERN Document Server

    Burns, R A; Hirota, T; Motogi, K; Imai, I; Omodaka, T

    2016-01-01

    Context. The S235AB star forming region houses a massive young stellar object which has recently been reported to exhibit possible evidence of jet rotation - an illusive yet crucial component of disk aided star formation theories. Aims. To confirm the presence of a molecular counterpart to the jet and to further study the molecular environment in in S235AB. Methods. We search for velocity wings in the line emission of thermal SiO (J=2-1, v=0), a tracer of shocked gas, which would indicate the presence of jet activity. Utilising other lines detected in our survey we use the relative intensities of intra species transitions, isotopes and hyperfine transitions to derive opacities, temperatures, column densities and abundances of various molecular species in S235AB. Results. The SiO (J=2-1, v=0) emission exhibits velocity wing of up to 75 km/s above and below the velocity of the star, indicating the presence of a jet. The molecular environment describes an evolutionary stage resemblant of a hot molecular core.

  4. Spectral emissivity of type E235B low carbon structural steel with different roughnesses

    Science.gov (United States)

    Yu, Kun; Zhang, Feilin; Liu, Dong; Liu, Yufang

    2017-08-01

    A self-built experimental apparatus was employed to study the spectral emissivity of type E235B low carbon structural steel in the wavelength range 2-15 μm at different temperatures by energy comparison method. The surface roughness and topography of the steel E235B were determined by a roughness tester and a scanning electron microscopy, respectively. And then, the spectral emissivity of steel E235B with six different roughnesses was measured before and after oxidation. The measurement results showed that the spectral emissivity increased with the increasing temperature and surface roughness before oxidation. The effect of roughness on the spectral emissivity is different at different wavelength and temperature ranges. However, the oscillatory behavior of the spectral emissivity was observed after oxidation. To explore the possible reasons for emissivity variation, the changes of surface roughness and optical roughness were investigated after oxidation. It is found that both the surface roughness and optical roughness increased after oxidation. Although the optical roughness can be used as one of the parameters to evaluate the effect of surface roughness on the spectral emissivity, it is insufficient to describe the effect of surface morphology on the spectral emissivity.

  5. Analysis of homogeneous U233 and U235 critical assemblies with ENDF/B-IV data (AWBA development program)

    Energy Technology Data Exchange (ETDEWEB)

    Ullo, J.J.; Hardy, J. Jr.

    1977-10-01

    Thirty-two U233 and U235 homogeneous aqueous critical experiments were analyzed with ENDF/B-IV data. Calculated eigenvalues for both fuel types increased by nearly 2 percent over the range of hydrogen/uranium atomic ratio covered (from 2106 to 27.1). This is attributed mostly to an underprediction of fast leakage, with some contribution from the fission and capture resonance integrals of ENDF/B-IV U235. Eigenvalue sensitivities to several nuclear data changes were examined. Values of the thermal criticality parameter constraint K2 for U233 and U235 were derived from the Gwin-Magnuson critical experiments at the zero leakage limit.

  6. Phytic acid as a corrosion inhibitor for 235 steel in NaCl solution%植酸自组装膜对Q235钢在氯化钠溶液中的缓蚀作用

    Institute of Scientific and Technical Information of China (English)

    王凤平; 胡隋军; 唐丽娜

    2014-01-01

    The corrosion inhibition of phytic acid on Q235 steel in NaCl solution was investigated by weight loss technique ,scanning electronic microscopy and the energy spectrum of X rays .The results show that inhibition efficiency of phytic acid on Q 235 steel in NaCl solution is obviously different at different pH .Phytic acid can accelerate the corrosion rate of Q 235 steel under acidic condition .But under neutral and alkaline condition ,phytic acid has excellent corrosion inhibition for 235steel in NaCl solution .Nevertheless ,the corrosion inhibition efficiency of phytic acid for Q235 steel in NaCl solu-tion increases with increasing phytic acid concentration under neutral and alkaline condition .If the concentration of phytic acid is 0 .5% ,the inhibition efficiency is more than 90% .%从植物中提取的植酸作金属缓蚀剂对环境保护具有重要意义.采用失重法、扫描电子显微镜和X射线能谱研究了植酸对Q235钢在NaCl溶液中的缓蚀行为以及影响因素.失重实验结果表明,不同p H值植酸对Q 235钢的缓蚀效果明显不同,在酸性条件下植酸加速Q235钢的腐蚀,在中性及碱性条件下,植酸对Q235钢的腐蚀具有明显的抑制作用.中性或碱性条件下,NaCl溶液中植酸对Q235钢缓蚀效率随植酸浓度的增加而增加,植酸浓度达0.5%以上时,缓蚀效率高达90%以上.扫描电镜结果表明,植酸处理后的Q235钢表面生成膜在不同pH下明显不同,碱性条件下的生成膜明显好于酸性条件下的生成膜.

  7. Corrosion behavior and electrochemical character of Q235 carbon steel in the presence of Penicillium%Q235钢在青霉菌作用下的腐蚀行为和电化学特性

    Institute of Scientific and Technical Information of China (English)

    李松梅; 王力锋; 杜娟; 刘建华; 于美

    2013-01-01

    采用表面分析技术、失重法及电化学测试方法研究了Q235钢在青霉菌(Penicillium)作用下的腐蚀行为和电化学特性.青霉菌在Q235钢表面形成致密的生物膜和腐蚀产物沉积膜层.青霉菌促进Q235钢的腐蚀,腐蚀类型为点蚀坑.青霉菌体系中试样表面膜经历由游离态变为固着态,由单层逐渐变为多层的过程;生物膜作用与细菌活性有关,当活性降低时微生物腐蚀促进作用也大幅降低.%The influenced corrosion behavior of Q235 carbon steel was investigated in the presence of Penicillium by using the surface analysis method, mass loss method, and electrochemical method. It is demonstrated that dense biofilms and depositing films of corrosion products form on the surface of Q235 carbon steel in the presence of Penicillium. Corrosion of Q235 carbon steel is evidently promoted and the corrosion morphology of Q235 carbon steel is pitting in Penicillium systems. The films on the surface of Q235 carbon steel changes through a complex process, from free state to solid state and single-layer to multilayer. The effect of the biofilm depends on bacterial activity, and the corrosion promotion of the biofilm decreases as the bacterial activity weakens.

  8. Clinical efficacy of complex splenectomy in 235 patients%235例复杂性脾切除术的临床疗效

    Institute of Scientific and Technical Information of China (English)

    关蛟; 周尊强; 佟大年; 张正筠; 周光文

    2016-01-01

    目的 探讨复杂性脾切除术的临床疗效和手术安全性.方法 采用回顾性队列研究方法.收集2005年1月至2015年12月收治的235例(上海交通大学医学院附属瑞金医院135例、上海交通大学附属第一人民医院67例、上海交通大学附属第六人民医院26例、解放军第八五医院7例)复杂性脾切除术患者的临床资料.患者均行全脾切除术,术中先行脾动脉结扎.观察指标:(1)患者手术情况.(2)主要并发症:腹腔内出血、肺部并发症、左膈下脓肿、腹腔积液.(3)随访情况:门静脉系统并发症(随访中脾静脉栓塞性静脉炎、脾静脉栓塞和门静脉主干栓塞),生存情况.采用门诊及电话方式随访,患者定期复查超声、腹部CT、血常规及凝血功能等情况,随访时间截至2016年3月.正态分布的计量资料采用-x±s表示,计数资料采用x2检验.结果 (1)手术情况:235例患者中,200例患者采用二级脾蒂离断术,35例患者采用非二级脾蒂离断术.235例患者术中出血量为(268±103) mL,脾切除时间为(82±29) min.(2)主要并发症:235例患者中31例出现术后并发症:腹腔内出血12例;肺部并发症17例;3例左膈下脓肿;21例大量腹腔积液,部分患者合并多种症状.上述并发症经再次手术和非手术治疗痊愈.(3)随访情况:门静脉系统并发症:脾静脉栓塞性静脉炎16例;脾静脉栓塞17例;脾静脉栓塞合并门静脉主干栓塞7例;均经抗炎、抗凝和溶栓治疗后好转.血吸虫肝硬化巨脾切除后栓塞率高达32.4% (12/37),而乙型病毒性肝炎肝硬化脾切除后栓塞率为8.1%(12/149),两者比较,差异有统计学意义(x2=10.9,P<0.05).生存情况:235例患者中228例获得随访,随访时间为(7.9±4.2)年.患者一般生存情况良好.结论 复杂性脾切除术安全有效,认真仔细的术前评估、精细轻柔的手术操作、脾蒂的正确处理和创面的腹膜化,是降低复杂性脾切除术

  9. Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs.

    Science.gov (United States)

    Guandalini, L; Martini, E; Di Cesare Mannelli, L; Dei, S; Manetti, D; Scapecchi, S; Teodori, E; Ghelardini, C; Romanelli, M N

    2012-03-01

    A series of analogs of DM235 and MN19, characterized by rings with different size, have been prepared and evaluated for their nootropic activity in the mouse passive-avoidance test. It was found that the optimal ring size for the analogs of DM235, showing endocyclic both amidic groups, is 6 or 7 atoms. For the compounds structurally related to MN19, carrying an exocyclic amide group, the piperidine ring is the moiety which gives the most interesting compounds.

  10. Q235-B+316L不锈钢复合板的焊接工艺

    Institute of Scientific and Technical Information of China (English)

    温新强; 温再菢

    2007-01-01

    通过对Q235-B+316L不锈钢复合板的焊接性分析,焊接方法、焊接材料和接头形式的选择,进行焊接工艺评定,来确定出合理的Q235-B+316L不锈钢复合板的焊接工艺.

  11. Electrocatalytic dechlorination of 2,3,5-trichlorophenol on palladium/carbon nanotubes-nafion film/titanium mesh electrode.

    Science.gov (United States)

    Sun, Zhirong; Ma, Xiaoyue; Hu, Xiang

    2017-06-01

    Palladium/carbon nanotubes-nafion film-modified titanium mesh electrode (Pd/CNTs-nafion film/Ti electrode) was prepared and used for catalytic dechlorination of 2,3,5-trichlorophenol (2,3,5-TCP). The influences of factors, such as Pd(2+) concentration, plating solution pH, and electrodeposition time and current, on the preparation of the electrode were studied by cyclic voltammetry (CV) to establish the optimal electrode preparation conditions. Additionally, the CV results highlighted that the addition of the CNTs-nafion film could enhance the electrochemical performance of the electrode. The Pd/CNTs-nafion film/Ti electrode was characterized by field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), and inductively coupled plasma-atomic emission spectrometry (ICP-AES). The electrode exhibited good stability and high catalytic dechlorination capacity on 2,3,5-TCP-100 mg L(-1) 2,3,5-TCP was completely dechlorinated within 100 min at a dechlorination current of 5 mA and an initial solution pH of 2.3. High-performance liquid chromatography (HPLC) was used to detect the chlorinated phenolic intermediates, and the results revealed that the final products were mainly phenol. The kinetics studies revealed that the dechlorination of 2,3,5-TCP followed two-stage mixed order kinetics, and a possible degradation pathway for 2,3,5-TCP was proposed.

  12. {alpha}-particle emission probabilities in the decay of {sup 235}U

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Torano, Eduardo [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain)]. E-mail: E.Garciatorano@ciemat.es; Teresa Crespo, M. [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain); Roteta, Miguel [Laboratorio de Metrologia de Radiaciones Ionizantes, CIEMAT, Madrid (Spain); Sibbens, Goedele [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (Belgium); Pomme, Stefaan [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, Geel (Belgium); Martin Sanchez, Alejandro [Departamento de Fisica, Universidad de Extremadura, Badajoz (Spain); Pilar Rubio Montero, M. [Departamento de Fisica, Universidad de Extremadura, Badajoz (Spain); Woods, Simon [Radioactivity Metrology Group, National Physical Laboratory, Teddington, Middlesex (United Kingdom); Pearce, Andy [Radioactivity Metrology Group, National Physical Laboratory, Teddington, Middlesex (United Kingdom)

    2005-09-21

    {sup 235}U decays by {alpha}-particle emission to {sup 231}Th. The decay scheme of this nuclide is very complex, with more than 20 alpha branches. Recommended values for P {sub {alpha}} of this nuclide are based on measurements carried out in 1975. This work presents the results of new measurements made with Si detectors and sources of enriched uranium in the frame of the EUROMET 591 cooperation project. The use of improved measurement techniques and numerical analysis of spectra allowed a new set of P {sub {alpha}} values for 13 lines with improved uncertainties to be obtained.

  13. Q235焊接接头的缝隙腐蚀行为%CREVICE CORROSION BEHAVIORS OF Q235 WELD JOINT

    Institute of Scientific and Technical Information of China (English)

    喻巧红; 刘超; 庞晓露; 刘泉林; 高克玮

    2014-01-01

    As a candidate package material for high level radiation waste disposal,the crevice corrosion behavior of Q235 low carbon steel weld joint was investigated in a solution simulated to the groundwater in the northwest part of China.The influences of temperature and oxygen content were evaluated.The microstructure of the weld joint was observed by OM,and SEM and surface profile were employed to analyze the crevice corrosion behavior of the weld joint.Open circuit potential of different regions of the weld joint was measured by electrochemical method.Experimental results indicated that the increases of temperature and oxygen content could promote the occurrence of crevice corrosion,and facilitate the corrosion processes both inside and outside the crevice.Fusion zone with a microstructure of clustered ferrite was the most severe corroded area in the weld joint,followed by weld metal,which was characterized by a coarse widmanstaetten structure.The microstructures of base metal and heat affected zone were fine and homogeneous,so these two regions underwent slighter corrosion.%针对我国特定地质处置环境,采用浸泡方法研究了高放废物包装容器候选材料Q235低碳钢焊接接头在模拟地下水溶液中的缝隙腐蚀行为,考察了温度以及溶液中氧浓度的影响.利用OM观察了焊接接头不同区域的显微组织,利用SEM和表面轮廓仪分析了不同区域的腐蚀行为,并采用电化学方法测量了各个区域的开路电位.结果表明,升高温度和氧含量能够促进缝隙腐蚀过程,并对缝隙内外的腐蚀过程均有促进作用.熔合区组织为大量聚集的铁素体组织,腐蚀最严重,其次是具有粗大魏氏体组织的焊缝区,母材区和热影响区组织相对均匀细小,腐蚀相对较轻.

  14. Q235基体上CMT-TWIN技术堆焊镍基合金%CMT-TWIN technology surfacing nickel-based alloys on the Q235 matrix

    Institute of Scientific and Technical Information of China (English)

    伍钢; 余进; 蒋凯; 罗滏

    2015-01-01

    以Q235为基体,以镍基合金Inconel625(φ1.0 mm焊丝)为堆焊材料,采用CMT-TWIN焊接技术进行堆焊,试验结果表明最佳参数为:电弧电压14.7 V,焊接电流98 A,焊接速度4mm/s,摆宽10mm(双丝参数一致),能够获得致密美观、无缺陷的镍基合金堆焊层.从熔合线附近到堆焊层中心,组织为树枝晶形态的奥氏体;EDS表明元素含量在熔合线附近发生突变的区域较窄(10~20 μm),而在堆焊层中分布较均匀,说明熔合比较小;剪切试验表明基体与堆焊层结合界面的抗剪强度大于326 MPa,断口形貌表明为韧性断裂.

  15. Consistent Data Assimilation of Actinide Isotopes: 235U and 239Pu

    Energy Technology Data Exchange (ETDEWEB)

    G. Palmiottti; H. Hiruta; M. Salvatores

    2011-09-01

    In this annual report we illustrate the methodology of the consistent data assimilation that allows to use the information coming from integral experiments for improving the basic nuclear parameters used in cross section evaluation. A series of integral experiments were analyzed using the EMPIRE evaluated files for {sup 235}U, {sup 238}U, and {sup 239}Pu. Inmost cases the results have shown quite large worse results with respect to the corresponding existing evaluations available for ENDF/B-VII. The observed discrepancies between calculated and experimental results were used in conjunction with the computed sensitivity coefficients and covariance matrix for nuclear parameters in a consistent data assimilation. Only the GODIVA and JEZEBEL experimental results were used, in order to exploit information relative to the isotope of interest that are, in this particular case: {sup 235}U and {sup 239}Pu. The results obtained by the consistent data assimilation indicate that with reasonable modifications (mostly within the initial standard deviation) it is possible to eliminate the original large discrepancies on the K{sub eff} of the two critical configurations. However, some residual discrepancy remains for a few fission spectral indices that are, most likely, to be attributed to the detector cross sections.

  16. Measurement of the ^235mU Production Cross Section Using a Critical Assembly*

    Science.gov (United States)

    Macri, Robert; Authier, Nicolas; Becker, John; Belier, Gilbert; Bond, Evelyn; Bredeweg, Todd; Glover, S.; Meot, Vincent; Rundberg, Robert; Vieira, David; Wilhelmy, Jerry

    2006-10-01

    Measurements of the creation and destruction cross sections for actinide nuclei constitute an important experimental effort in support of Stockpile Stewardship. In this talk I will give a progress report on the effort to measure the production cross section of the ^235mU isomer integrated over a fission neutron spectrum. This ongoing experiment is fielded at CEA in Valduc, France, taking advantage of the CALIBAN critical assembly. This effort is performed in collaboration with LANL, LLNL, Bruyeres le Chatel, and Valduc staff. This experiment utilizes a technique to measure internal conversion electrons from the ^235mU isomer with the French BIII detector (Bruyeres le Chatel), and involves a substantial chemistry effort (LANL) to prepare targets for irradiation and counting, as well as to remove fission fragments after irradiation. Experimental techniques will be discussed and preliminary data presented. *Work performed under the auspices of the U.S. Department of Energy by Los Alamos National Laboratory (W-7405-ENG-36) and Lawrence Livermore National Laboratory (W-7405-ENG-48), and CEA-DAM under CEA-DAM NNSA-DOE agreement.

  17. Total kinetic energy release in the fast neutron-induced fission of $^{235}$U

    CERN Document Server

    Yanez, R; King, J; Barrett, J S; Fotiades, N; Lee, H Y

    2015-01-01

    We have measured the total kinetic energy (TKE) release for the $^{235}$U(n,f) reaction for $E_{n}$=2-100 MeV using the 2E method with an array of Si PIN diode detectors. The neutron energies were determined by time of flight measurements using the white spectrum neutron beam at the LANSCE facility. (To calibrate the apparatus, the TKE release for $^{235}$U(n$_{th}$,f) was also measured using a thermal neutron beam from the OSU TRIGA reactor). The TKE decreases non-linearly from 169.0 MeV to 161.4 MeV for $E_{n}$=2-90 MeV. The standard deviation of the TKE distribution is constant from $E_{n}$=20-90 MeV. Comparison of the data with the multi-modal fission model of Brosa indicates the TKE decrease is a consequence of the growth of symmetric fission and the corresponding decrease of asymmetric fission with increasing neutron energy. The average TKE associated with the Brosa superlong, standard I and standard II modes for a given mass is independent of neutron energy.

  18. New Precision Measurements of the U235(n,γ) Cross Section

    Science.gov (United States)

    Jandel, M.; Bredeweg, T. A.; Bond, E. M.; Chadwick, M. B.; Couture, A.; O'Donnell, J. M.; Fowler, M.; Haight, R. C.; Kawano, T.; Reifarth, R.; Rundberg, R. S.; Ullmann, J. L.; Vieira, D. J.; Wouters, J. M.; Wilhelmy, J. B.; Wu, C. Y.; Becker, J. A.

    2012-11-01

    The neutron capture cross section of U235 was measured for the neutron incident energy region between 4 eV and 1 MeV at the DANCE facility at the Los Alamos Neutron Science Center with an unprecedented accuracy of 2-3% at 1 keV. The new methodology combined three independent measurements. In the main experiment, a thick actinide sample was used to determine neutron capture and neutron-induced fission rates simultaneously. In the second measurement, a fission tagging detector was used with a thin actinide sample and detailed characteristics of the prompt-fission gamma rays were obtained. In the third measurement, the neutron scattering background was characterized using a sample of Pb208. The relative capture cross section was obtained from the experiment with the thick U235 sample using a ratio method after the subtraction of the fission and neutron scattering backgrounds. Our result indicates errors that are as large as 30% in the 0.5-2.5 keV region, in the current knowledge of neutron capture as embodied in major nuclear data evaluations. Future modifications of these databases using the improved precision data given herein will have significant impacts in neutronics calculations for a variety of nuclear technologies.

  19. New precision measurements of the 235U(n,γ) cross section.

    Science.gov (United States)

    Jandel, M; Bredeweg, T A; Bond, E M; Chadwick, M B; Couture, A; O'Donnell, J M; Fowler, M; Haight, R C; Kawano, T; Reifarth, R; Rundberg, R S; Ullmann, J L; Vieira, D J; Wouters, J M; Wilhelmy, J B; Wu, C Y; Becker, J A

    2012-11-16

    The neutron capture cross section of (235)U was measured for the neutron incident energy region between 4 eV and 1 MeV at the DANCE facility at the Los Alamos Neutron Science Center with an unprecedented accuracy of 2-3% at 1 keV. The new methodology combined three independent measurements. In the main experiment, a thick actinide sample was used to determine neutron capture and neutron-induced fission rates simultaneously. In the second measurement, a fission tagging detector was used with a thin actinide sample and detailed characteristics of the prompt-fission gamma rays were obtained. In the third measurement, the neutron scattering background was characterized using a sample of (208)Pb. The relative capture cross section was obtained from the experiment with the thick (235)U sample using a ratio method after the subtraction of the fission and neutron scattering backgrounds. Our result indicates errors that are as large as 30% in the 0.5-2.5 keV region, in the current knowledge of neutron capture as embodied in major nuclear data evaluations. Future modifications of these databases using the improved precision data given herein will have significant impacts in neutronics calculations for a variety of nuclear technologies.

  20. Molecular Emission in Dense Massive Clumps from the Star-Forming Regions S231-S235

    CERN Document Server

    Ladeyschikov, D A; Tsivilev, A P; Sobolev, A M

    2016-01-01

    The article deals with observations of star-forming regions S231-S235 in 'quasi-thermal' lines of ammonia (NH$_3$), cyanoacetylene (HC$_3$N) and maser lines of methanol (CH$_3$OH) and water vapor (H$_2$O). S231-S235 regions is situated in the giant molecular cloud G174+2.5. We selected all massive molecular clumps in G174+2.5 using archive CO data. For the each clump we determined mass, size and CO column density. After that we performed observations of these clumps. We report about first detections of NH$_3$ and HC$_3$N lines toward the molecular clumps WB89 673 and WB89 668. This means that high-density gas is present there. Physical parameters of molecular gas in the clumps were estimated using the data on ammonia emission. We found that the gas temperature and the hydrogen number density are in the ranges 16-30 K and 2.8-7.2$\\times10^3$ cm$^{-3}$, respectively. The shock-tracing line of CH$_3$OH molecule at 36.2 GHz is newly detected toward WB89 673.

  1. A multi-wavelength study of star formation activity in the S235 complex

    CERN Document Server

    Dewangan, L K; Luna, A; Anandarao, B G; Ninan, J P; Mallick, K K; Mayya, Y D

    2016-01-01

    We have carried out an extensive multi-wavelength study to investigate the star formation process in the S235 complex. The S235 complex has a sphere-like shell appearance at wavelengths longer than 2 $\\mu$m and harbors an O9.5V type star approximately at its center. Near-infrared extinction map traces eight subregions (having A$_{V}$ $>$ 8 mag), and five of them appear to be distributed in an almost regularly spaced manner along the sphere-like shell surrounding the ionized emission. This picture is also supported by the integrated $^{12}$CO and $^{13}$CO intensity maps and by Bolocam 1.1 mm continuum emission. The position-velocity analysis of CO reveals an almost semi-ring like structure, suggesting an expanding H\\,{\\sc ii} region. We find that the Bolocam clump masses increase as we move away from the location of the ionizing star. This correlation is seen only for those clumps which are distributed near the edges of the shell. Photometric analysis reveals 435 young stellar objects (YSOs), 59\\% of which ar...

  2. Propagation Channel Comparison between 23.5 and 45 GHz in Conference Scenario

    Directory of Open Access Journals (Sweden)

    Jianwu Dou

    2016-01-01

    Full Text Available The characteristics of propagation channel at 23.5 and 45 GHz in an indoor conference room are studied based on hybrid approach. A ray-based simulator which includes the reflection, penetration, diffraction, and diffuse scattering is adopted to generate the massive channel realizations. This platform is well calibrated in path and power delay profile (PDP levels according to some specified measurements at different frequencies. Subsequently, according to the simulated channel samples, the statistical channel model for both the large and small scale characteristics is established based on the alpha-beta approach and extended Saleh-Valenzuela (S-V structure, respectively. Results show that the slope of fitted path loss (PL is less than free space due to the waveguide effect for both 23.5 and 45 GHz in indoor scenario and larger PL is experienced at higher frequency. Additionally, the cluster is more centralized with less spreads and decaying faster in delay domain at 45 GHz.

  3. Combined therapy with RAD001 e BEZ235 overcomes resistance of PET immortalized cell lines to mTOR inhibition.

    Science.gov (United States)

    Passacantilli, Ilaria; Capurso, Gabriele; Archibugi, Livia; Calabretta, Sara; Caldarola, Sara; Loreni, Fabrizio; Delle Fave, Gianfranco; Sette, Claudio

    2014-07-30

    Pancreatic endocrine tumors (PETs) are characterised by an indolent behaviour in terms of tumor growth. However, most patients display metastasis at diagnosis and no cure is currently available. Since the PI3K/AKT/mTOR axis is deregulated in PETs, the mTOR inhibitor RAD001 represents the first line treatment. Nevertheless, some patients do not respond to treatments and most acquire resistance. Inhibition of mTOR leads to feedback re-activation of PI3K activity, which may promote resistance to RAD001. Thus, PI3K represents a novel potential target for PETs. We tested the impact of three novel PI3K inhibitors (BEZ235, BKM120 and BYL719) on proliferation of PET cells that are responsive (BON-1) or unresponsive (QGP-1) to RAD001. BEZ235 was the most efficient in inhibiting proliferation in PET cells. Furthermore, combined treatment with BEZ235 and RAD001 exhibited synergic effects and was also effective in BON-1 that acquired resistance to RAD001 (BON-1 RR). Analysis of PI3K/AKT/mTOR pathway showed that RAD001 and BEZ235 only partially inhibited mTOR-dependent phosphorylation of 4EBP1. By contrast, combined therapy with the two inhibitors strongly inhibited phosphorylation of 4EBP1, assembly of the translational initiation complex and protein synthesis. Thus, combined treatment with BEZ235 may represent suitable therapy to counteract primary and acquired resistance to RAD001 in PETs.

  4. 238U/235U variations in meteorites: extant 247Cm and implications for Pb-Pb dating.

    Science.gov (United States)

    Brennecka, G A; Weyer, S; Wadhwa, M; Janney, P E; Zipfel, J; Anbar, A D

    2010-01-22

    The 238U/235U isotope ratio has long been considered invariant in meteoritic materials (equal to 137.88). This assumption is a cornerstone of the high-precision lead-lead dates that define the absolute age of the solar system. Calcium-aluminum-rich inclusions (CAIs) of the Allende meteorite display variable 238U/235U ratios, ranging between 137.409 +/- 0.039 and 137.885 +/- 0.009. This range implies substantial uncertainties in the ages that were previously determined by lead-lead dating of CAIs, which may be overestimated by several million years. The correlation of uranium isotope ratios with proxies for curium/uranium (that is, thorium/uranium and neodymium/uranium) provides strong evidence that the observed variations of 238U/235U in CAIs were produced by the decay of extant curium-247 to uranium-235 in the early solar system, with an initial 247Cm/235U ratio of approximately 1.1 x 10(-4) to 2.4 x 10(-4).

  5. Gastrointestinal Salmonella Infection:Analysis of 235 Cases%沙门菌胃肠道感染235例分析

    Institute of Scientific and Technical Information of China (English)

    齐绪林; 林东昉; 徐晓刚; 卜淑蕊

    2015-01-01

    目的:了解沙门菌胃肠道感染的临床特征及流行病学特点。方法:回顾分析1998—2013年在复旦大学附属金山医院肠道门诊就诊的沙门菌胃肠道感染患者的临床资料及流行病学特点。结果:1998—2013年在复旦大学附属金山医院肠道门诊就诊的腹泻患者中共检出沙门菌感染者235例,以2006—2013年检出的病例为主,占96.17%,每年的5月到10月为沙门菌感染高发期。沙门菌感染多在食用污染的食物12~24 h后起病,临床表现为腹痛、腹泻及发热;排便每日3~4次至20~30次,多呈水样,粪便中偶含有黏液或呈脓血便;患者体温波动于38~39.4℃,可伴有畏寒。健康的成年人感染沙门菌后症状持续2~5d后可恢复,而年老体弱者则可持续较长时间。呕吐、腹泻严重者可发生严重脱水。结论:了解沙门菌的临床表现、发病特点及流行病学特点,有利于该类疾病的早期临床诊断和治疗。%Objective:To understand the clinical and epidemiological characteristics of gastrointestinal salmonella infection . Methods:The clinical and epidemiological characteristics of patients with gastrointestinal salmonella infection in Enteric Diseases Clinic of Jinshan Hospital affiliated to Fudan Uninversity during 1998 and 2013 ,were retrospectively analyzed .Results:During 1998 and 2013 ,235(96 .17% was recent 8 years) cases with Salmonella infection were checked out from patients with diarrhea in Enteric Diseases Clinic of Jinshan Hospital affiliated to Fudan University .Most of the cases(96 .17% ) were checked out dur‐ing 2006 and 2013 .The annual high prevalence of salmonella infection was during May and October .The onset of salmonella infection was mainly 12‐24 h after eating salmonella contaminated food .The manifestation was mainly abdominal pain ,diarrhe‐a ,and fever .Daily defecation times were from 3‐4 times to 20‐30 times .Watery stool was most

  6. Evaluation of borated aluminum products for criticality control in 235-F

    Energy Technology Data Exchange (ETDEWEB)

    Crouch, W. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2003-04-01

    Plutonium-containing materials are destined for storage in the 235-F vault. The projected amount of stored materials will require the presence of neutron absorber materials. The leading design concept is for the neutron absorber materials to be in non-load-bearing borated aluminum plates lining the walls of the vault. A comprehensive evaluation of the borated aluminum plate materials was performed to identify a suitable material, and verify that these materials would remain effective as neutron absorbers under normal service conditions and for design-basis events, including the fire accident scenario, throughout a 20-year service life. Aluminum 1100 with boron additions is the recommended neutron absorber material for plutonium material storage in the 235-F vault based on boron loading capacity and durability in the storage environment. Borated aluminum 1100 is commercially available up to 4.5 wt. % boron. A detailed comparison was made of the physical, mechanical, and corrosion properties of borated aluminum alloy 1100 to standard alloy 1100-O1 to demonstrate near-equivalency in properties and to justify application of alloy 1100-O properties to the borated product as needed for the degradation analysis. The expected degradation of the borated aluminum is extremely low for storage conditions, including the bounding scenario of an aggressive atmospheric condition. A maximum loss of 0.00029 inches/year would be expected under potentially aggressive atmospheric conditions and would result in a fractional loss of only 0.42 wt. % of the boron present in a 7mm plate for a 20-year storage period. The fraction of Boron-10 consumption by spontaneous neutrons is expected to be less than 10-8 for the 20-year storage in 235-F fully loaded with Pu materials. The borated aluminum alloy 1100 will be thermally stable and unaltered up to near-melt temperature (643°C). Mechanical testing data at elevated temperatures show that the strengths (yield and ultimate) of the borated

  7. Evaluation of borated aluminum products for criticality control in 235-F

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, A. [Savannah River Site (SRS), Aiken, SC (United States); Sindelar, R. [Savannah River Site (SRS), Aiken, SC (United States)

    2003-05-06

    Plutonium-containing materials are destined for storage in the 235-F vault. The projected amount of stored materials will require the presence of neutron absorber materials. The leading design concept is for the neutron absorber materials to be in non-load-bearing borated aluminum plates lining the walls of the vault. A comprehensive evaluation of the borated aluminum plate materials was performed to identify a suitable material, and verify that these materials would remain effective as neutron absorbers under normal service conditions and for design-basis events, including the fire accident scenario, throughout a 20-year service life. Aluminum 1100 with boron additions is the recommended neutron absorber material for plutonium material storage in the 235-F vault based on boron loading capacity and durability in the storage environment. Borated aluminum 1100 is commercially available up to 4.5 wt. % boron. A detailed comparison was made of the physical, mechanical, and corrosion properties of borated aluminum alloy 1100 to standard alloy 1100-O (-O designating the fully annealed condition) to demonstrate near-equivalency in properties and to justify application of alloy 1100-O properties to the borated product as needed for the degradation analysis. The expected degradation of the borated aluminum is extremely low for storage conditions, including the bounding scenario of an aggressive atmospheric condition. A maximum loss of 0.00029 inches/year would be expected under potentially aggressive atmospheric conditions and would result in a fractional loss of only 0.42 wt.% of the boron present in a 7mm plate for a 20-year storage period. The fraction of Boron-10 consumption by spontaneous neutrons is expected to be less than 10{sup -8} for the 20-year storage in 235-F fully loaded with Pu materials. The borated aluminum alloy 1100 will be thermally stable and unaltered up to near-melt temperature (643°C). Mechanical testing data at elevated temperatures show that the

  8. The Software Design for252Cf Neutron Activation Fuel Rod 235U Enrichment Inspecting Equipment%252Cf中子活化核燃料棒235U富集度检测设备的软件设计

    Institute of Scientific and Technical Information of China (English)

    张雷; 刘明; 马金波

    2013-01-01

    It introduces the software design for 252Cf neutron activation fuel red235U enrichment inspecting equipment.It used multithread technique to control Advantech PCI-1780 counter/timer card,and collect γ-ray signal from the six-path detectors.Process and analyze the collected data can exactly check the actual 235U enrichment and abnormal pellets in the nuclear fuel rods.The software can measure the actual 235U enrichment and judge whether there are abnormal pellets in the nuclear fuel rods accurately,and send customizing messages to PLC which complete automatic sorting,at 6 m/min detection speed.Now the software is used on nondestructive test equipment in Nuclear Fuel Element Factory.%介绍了252Cf中子活化核燃料棒235U富集度检测设备的软件设计,该软件采用多线程技术控制研华PCI-1780采集卡定时采集六路探测器输出的经252Cf中子活化后235U裂变产物的γ射线信号,针对采集数据的特性,进行相应的处理和分析,可以检测出核燃料棒的实际235U富集度以及有无异常芯块.该软件经过实验验证在检测速度为6时,能够准确测量核燃料棒的实际235U富集度值并判断棒中是否混有异常芯块,同时向PLC发送相应信号实现自动分选.目前已应用在核燃料元件厂的核燃料棒235U富集度无损检测设备上.

  9. Determination of Uranium and Thorium in Water by N-235 extraction/Spectrophotometric Method%N-235萃取/分光光度法测定水中铀和钍

    Institute of Scientific and Technical Information of China (English)

    周花珑; 甘毓璘; 黄彬丽

    2012-01-01

      用N-235作为萃取剂,偶氮砷Ⅲ作为显色剂,用分光光度法测定水中的铀和钍。结果表明:铀、钍的回收率在80%以上,方法稳定可靠。%  With N-235 as the extraction and Azo arsenic Ⅲ as the chromogenic reagent, Uranium and Thorium in the water were determined by spectrophotometry. The results showed that the recoveries of Uranium and Thorium were above 80%,the method is stable and reliable.

  10. Comparison of {sup 235}U fission cross sections in JENDL-3.3 and ENDF/B-VI

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko [Kyushu Univ., Fukuoka (Japan); Carlson, Allan D. [National Institute of Standards and Technology (United States); Matsunobu, Hiroyuki [Data Engineering, Inc., Fujisawa, Kanagawa (Japan); Nakagawa, Tsuneo; Shibata, Keiichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Talou, Patrick; Young, Philip G.; Chadwick, Mark B. [Los Alamos National Laboratory, Los Alamos, NM (United States)

    2002-01-01

    Comparisons of evaluated fission cross sections for {sup 235}U in JENDL-3.3 and ENDF/B-VI are carried out. The comparisons are made for both the differential and integral data. The fission cross sections as well as the fission ratios are compared with the experimental data in detail. Spectrum averaged cross sections are calculated and compared with the measurements. The employed spectra are the {sup 235}U prompt fission neutron spectrum, the {sup 252}Cf spontaneous fission neutron spectrum, and the neutron spectrum produced by a {sup 9}Be(d, xn) reaction. For {sup 235}U prompt fission neutron spectrum, the ENDF/B-VI evaluation reproduces experimental averaged cross sections. For {sup 252}Cf and {sup 9}Be(d, xn) neutron spectra, the JENDL-3.3 evaluation gives better results than ENDF/B-VI. (author)

  11. An examination of the potential fission-bomb weaponizability of nuclides other than 235U and 239Pu

    Science.gov (United States)

    Reed, B. Cameron

    2017-01-01

    Long-lived fissionable isotopes other than uranium-235 and plutonium-239 are examined for possible use in fission weapons. A few other isotopes are potentially weaponizable and in some cases have been tried or their criticality experimentally demonstrated. In most cases, however, promising isotopes are either extremely rare, difficult to produce in quantity, or hazardous to handle. Some isotopes can serve to boost the yield of fission weapons, but 235U and 239Pu are likely to remain the only practical primary fuels for nuclear weapons. In view of this, and the fact that this analysis gives no engineering details on the design of nuclear weapons, this paper will be of no assistance to putative bomb-makers; rather, my purpose is to clarify the physics similarities between 235U and 239Pu that make them suitable candidates for fission weapons.

  12. Intermediate structure in the keV fission cross section of /sup 235/U

    Energy Technology Data Exchange (ETDEWEB)

    Migneco, E. (Univ., Catania, Italy); Bonsignore, P.; Lanzano, G.; Wartena, J.A.; Weigmann, H.

    1975-10-01

    The relative fission cross section of /sup 235/U has been measured up to 200 keV with a nominal resolution of 1.0 ns/m, using a thin foil plastic scintillator detector. The data have been analyzed in order to detect nonstatistical effects due to intermediate structure. Statistical tests which have been applied to this fission and similar total cross section data include calculations of the auto-correlation function and Wald-Wolfowitz tests on the cross section and on the autocorrelograms. The comparison of the results indicates the presence of intermediate structure effects in fission cross-section which may be interpreted on the basis of the double-humped deformation potential. 5 figures. (auth)

  13. High-Resolution Correlated Fission Product Measurements of 235U (nth , f) with SPIDER

    Science.gov (United States)

    Shields, Dan; Spider Team

    2015-10-01

    The SPIDER detector (SPectrometer for Ion DEtermination in fission Research) has obtained high-resolution, moderate-efficiency, correlated fission product data needed for many applications including the modeling of next generation nuclear reactors, stockpile stewardship, and the fundamental understanding of the fission process. SPIDER simultaneously measures velocity and energy of both fission products to calculate fission product yields (FPYs), neutron multiplicity (ν), and total kinetic energy (TKE). These data will be some of the first of their kind available to nuclear data evaluations. An overview of the SPIDER detector, analytical method, and preliminary results for 235U (nth , f) will be presented. LA-UR-15-20130 This work benefited from the use of the LANSCE accelerator facility and was performed under the auspices of the US Department of Energy by Los Alamos Security, LLC under Contract DE-AC52-06NA25396.

  14. High accuracy 235U(n,f data in the resonance energy region

    Directory of Open Access Journals (Sweden)

    Paradela C.

    2016-01-01

    Full Text Available The 235U neutron-induced cross section is widely used as reference cross section for measuring other fission cross sections, but in the resonance region it is not considered as an IAEA standard because of the scarce experimental data covering the full region. In this work, we deal with a new analysis of the experimental data obtained with a detection setup based on parallel plate ionization chambers (PPACs at the CERN n_TOF facility in the range from 1 eV to 10 keV. The relative cross section has been normalised to the IAEA value in the region between 7.8 and 11 eV, which is claimed as well-known. Comparison with the ENDF/B-VII evaluation and the IAEA reference file from 100 eV to 10 keV are provided.

  15. Investigating Prompt Fission Neutron Emission from 235U(n,f in the Resolved Resonance Region

    Directory of Open Access Journals (Sweden)

    Göök Alf

    2016-01-01

    Full Text Available Investigations of prompt emission in fission is of importance in understanding the fission process in general and the sharing of excitation energy among the fission fragments in particular. Experimental activities at IRMM on prompt neutron emission from fission in response to OECD/NEA nuclear data requests is presented in this contribution. Main focus lies on currently on-going investigations of prompt neutron emission from the reaction 235U(n,f in the region of the resolved resonances. For this reaction strong fluctuations of fission fragment mass distributions and mean total kinetic energy have been observed [Nucl. Phys. A 491, 56 (1989] as a function of incident neutron energy in the resonance region. In addition fluctuations of prompt neutron multiplicities were also observed [Phys. Rev. C 13, 195 (1976]. The goal of the present study is to verify the current knowledge of prompt neutron multiplicity fluctuations and to study correlations with fission fragment properties.

  16. Calibration and field application of a Sierra Model 235 cascade impactor

    Energy Technology Data Exchange (ETDEWEB)

    Knuth, R.H.

    1984-06-01

    A Sierra Model 235 slotted impactor was used to measure the particle size distribution of ore dust in uranium concentrating mills. The impactor was calibrated at a flow rate of 0.21 m/sup 3//min, using solid monodisperse particles of methylene blue and an impaction surface of Whatman number41 filter paper soaked in mineral oil. The reduction from the impactor's design flow rate of 1.13 m/sup 3//min (40 cfm) to 0.21 m/sup 3//min (7.5 cfm), a necessary adjustment because of the anticipated large particle sizes of ore dust, increased the stage cut-off diameters by an average factor of 2.3. Evaluation of field test results revealed that the underestimation of mass median diameters, often caused by the rebound and reentrainment of solid particles from dry impaction surfaces, was virtually eliminated by using the oiled Whatman number41 impaction surface.

  17. Prediction of Austenitization and Homogenization of Q235 Plain Carbon Steel during Reheating Process

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In this paper, the austenitization and homogenization process of Q235 plain carbon steel during reheating is predictedusing a two-dimensional model which has been developed for the prediction of diffusive phase transformation (e.g.α to γ). The diffusion equations are solved within each phase (α and γ) and an explicit finite volume techniqueformulated for a regular hexagonal grid are used. The discrete interface is represented by special volume elementsα/γ, an volume element α undergoes a transition to an interface state before it becomes γ. The procedure allowsus to handle the displacement of the interface while respecting the flux condition at the interface. The simulatedmicrostructure shows the dissolution of ferrite particles in the austenite matrix is presented at different stages ofthe phase transformation. Specifically, the influence of the microstructure scale and the heating rate on the phasetransformation kinetics has been investigated. The experimental results agree well with the simulated ones.

  18. Analyzing the thermionic reactor critical experiments. [thermal spectrum of uranium 235 core

    Science.gov (United States)

    Niederauer, G. F.

    1973-01-01

    The Thermionic Reactor Critical Experiments (TRCE) consisted of fast spectrum highly enriched U-235 cores reflected by different thicknesses of beryllium or beryllium oxide with a transition zone of stainless steel between the core and reflector. The mixed fast-thermal spectrum at the core reflector interface region poses a difficult neutron transport calculation. Calculations of TRCE using ENDF/B fast spectrum data and GATHER library thermal spectrum data agreed within about 1 percent for the multiplication factor and within 6 to 8 percent for the power peaks. Use of GAM library fast spectrum data yielded larger deviations. The results were obtained from DOT R Theta calculations with leakage cross sections, by region and by group, extracted from DOT RZ calculations. Delineation of the power peaks required extraordinarily fine mesh size at the core reflector interface.

  19. Atmospheric Corrosion of Q235 Carbon Steel and Q450 Weathering Steel in Turpan,China

    Institute of Scientific and Technical Information of China (English)

    Qiang YU; Chao-fang DONG; Yue-hua FANG; Kui XIAO; Chun-yun GUO; Gang HE; Xiao-gang LI

    2016-01-01

    Q235 carbon steel and Q450 weathering steel were exposed to the hot and dry environment of Turpan, China for three years.The corrosion rates of both steels were calculated and compared.The morphologies of the rust layer products were observed by optical microscopy and scanning electron microscopy.Analyses of the rust layers were performed by X-ray photoelectron spectroscopy,X-ray powder diffraction,and Raman spectroscopy,and anal-ysis results indicate that the compositions of rust are main iron rich oxide such as FeOOH,Fe3 O4 ,and Fe2 O3 .The iron oxide layer content proportion was calculated through a semi-quantitative algorithm.The resistance elements (Cr,Ni,and Cu)enhanced the resistance properties of the Q450 weathering steel matrix.Moreover,the resistance elements increased the proportion of goethite crystals in the corroded rust layer.

  20. Phytic acid doped polyaniline containing epoxy coatings for corrosion protection of Q235 carbon steel

    Science.gov (United States)

    Hao, Yongsheng; Sani, Luqman Abdullahi; Ge, Tiejun; Fang, Qinghong

    2017-10-01

    Corrosion protection of epoxy coatings contained with phytic acid-doped polyaniline (PANI-PA) for Q235 carbon steel was studied in this work. Synthesized PANI-PA particles were characterized by XPS, TGA, and FTIR, respectively. The coating performance was investigated by OCP, EIS, and SVET, respectively. The experimental results show that the concentration of PANI-PA has a significant influence to the barrier effect of the epoxy coating. Epoxy coating loaded with 2 wt.% PANI-PA has the best protection ability and self-healing function to a certain degree. The self-healing function of PANI-PA is attributed to the synergistic effect of the passivation of PANI and the chelation of the dedoped phytic acid ions with iron ions. Therefore, PANI-PA can be used as an effective anticorrosion pigment in future.

  1. Prompt fission neutron investigation in 235U(nth,f) reaction

    Science.gov (United States)

    Zeynalov, Shakir; Sedyshev, Pavel; Shvetsov, Valery; Sidorova, Olga

    2017-09-01

    The prompt neutron emission in thermal neutron induced fission of 235U has been investigated applying digital signal electronics. The goal was to compare the results of this digital data acquisition and digital signal processing analysis to the results of the pioneering work of Apalin et al. Using a twin Frisch grid ionization chamber for the fission fragment detection and a NE213 equivalent neutron detector in total about 106 neutron coincidences have been registered. The fission fragment kinetic energy, mass and angular distribution has been investigated along with prompt neutron time of flight and pulse shape using a six channel synchronous waveform digitizer with sampling frequency of 250 MHz and 12 bit resolution. The signals have been analyzed using digital pulse processing algorithms, developed by authors. The thermal neutron beam was transported from the IBR-2 reactor to the target with bent mirror neutron guide.

  2. Measurements of γ-ray Energy and Multiplicity from 235U(nthermal using STEFF

    Directory of Open Access Journals (Sweden)

    Pollitt A.J.

    2015-01-01

    Full Text Available The amount of energy carried by γ-rays during the fission process is an important consideration when developing new reactor designs. Many studies of γ-ray energy and multiplicity, from a multitude of fissioning systems, were measured during the 1970s. However the data from such experiments largely underestimates the heating effect caused by γ-rays in the structure of a reactor. It is therefore essential to obtain more accurate measurements of the energy carried during γ-ray emission. As such, the OECD Nuclear Energy Agency has put out a high priority request [1] for measurements of the mean γ-ray energy and multiplicity to an accuracy better than 7.5 percent from several fissioning systems; including 235U(nthermal. Measurements of the rays from these fissioning nuclei were performed with the SpecTrometer for Exotic Fission Fagments (STEFF.

  3. 中性盐雾腐蚀环境中Q235钢板力学性能的退化规律%Degradation Law of Mechanical Properties of Q235 Steel Plate in Neutral Salt Spray Corrosion Environment

    Institute of Scientific and Technical Information of China (English)

    徐善华; 王皓; 苏磊

    2016-01-01

    Accelerated corrosion test was carried out on Q235 steel plate in neutral salt spray corrosion environment for 0-178 days,and then the data of corroded steel plate surface were collected by using optical surface measurement technology to establish the corroded surface geometry model of Q235 steel plate by Geomagic studio.Degradation law of mechanical properties of Q235 steel plate were investigated by uniaxial tensile tests.The results show that yield strength,tensile strength and elongation obeyed a linear degradation with the increase of corrosion mass loss ratio,the yield platform became shorter rapidly.The corroded steel plate with big pits more easily entered its stage of necking because of plastic damage.By modifying the second plastic flow model,the stress-strain constitutive degradation model of corroded Q235 steel plate was established,and the degradation law of the model shape control parameters based on the corrosion mass loss ratio was achieved finally.In neutral salt spray corrosion environment,the main corrosion feature of Q235 steel plate was pitting corrosion,corrosion pit exhibited uneven distribution,separate characteristic and randomness,however,the effect of layered erosion could not be ignored.%在中性盐雾腐蚀环境中对 Q235钢板进行0~178 d的加速腐蚀试验,采用光学表面测量技术对锈蚀钢板表面进行数据采集,运用Geomagic studio逆向工程软件建立了 Q235钢板锈蚀表面的几何模型;通过单轴拉伸试验研究了 Q235钢板力学性能的退化规律。结果表明:随着锈蚀质量损失率增大,Q235钢板的屈服强度、抗拉强度和断后伸长率均呈明显的线性退化趋势,屈服平台迅速缩短,严重蚀坑的存在使得锈蚀钢板更易产生塑性损伤而进入颈缩阶段;通过对二次塑流模型进行修正,建立了锈蚀 Q235钢板的应力-应变退化本构模型,得到了模型形状控制参数随锈蚀质量损失率变化的退化规律

  4. Nosocomial dissemination of VIM-2-producing ST235 Pseudomonas aeruginosa in Lithuania.

    Science.gov (United States)

    Mikucionyte, G; Zamorano, L; Vitkauskiene, A; López-Causapé, C; Juan, C; Mulet, X; Oliver, A

    2016-02-01

    Pseudomonas aeruginosa multidrug resistance, and particularly the production of carbapenemases linked to international high-risk clones, is of growing concern. While high levels of carbapenem resistance (>60 %) have been reported in Lithuania, so far, there is no information on the underlying mechanisms. Thus, the aim of this work was to determine the molecular epidemiology and prevalence of acquired carbapenemases among 73 carbapenem-resistant P. aeruginosa isolates recovered in a hospital from Kaunas, Lithuania in 2011-2012. The presence of acquired carbapenemases was evaluated through phenotypic (modified Hodge test, cloxacillin inhibition test, double-disc synergy test) and genetic methods [polymerase chain reaction (PCR) and sequencing]. Clonal relatedness was assessed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). Acquired β-lactamases were detected in 19 (26 %) of the isolates, whereas resistance was exclusively chromosomal (OprD inactivation ± AmpC hyperproduction) in the remaining 54 (74 %) isolates. The acquired β-lactamases detected included 16 VIM-2, one PER-1 and two GES enzymes. PFGE revealed that 15 of the 16 VIM-2 isolates belonged to a single clone, identified as the international high-risk clone ST235 by MLST. bla VIM-2 was preceded by aacA7 in a class I integron, similar to epidemic ST235 isolates described in nearby countries. Additionally, sequencing of bla GES revealed the presence of the carbapenem-hydrolysing enzyme GES-5 in one of the isolates and a novel GES variant, designated GES-27, in the other. GES-27 differed from GES-5 by a single amino acid substitution, proline 167, that was replaced by glutamine. Increasing emergence and dissemination of concerning resistance mechanisms and international clones warrants global surveillance and control strategies.

  5. A MULTI-WAVELENGTH STUDY OF STAR FORMATION ACTIVITY IN THE S235 COMPLEX

    Energy Technology Data Exchange (ETDEWEB)

    Dewangan, L. K.; Luna, A.; Mayya, Y. D. [Instituto Nacional de Astrofísica, Óptica y Electrónica, Luis Enrique Erro # 1, Tonantzintla, Puebla, C.P. 72840, México (Mexico); Ojha, D. K.; Ninan, J. P.; Mallick, K. K. [Department of Astronomy and Astrophysics, Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400 005 (India); Anandarao, B. G., E-mail: lokeshd@prl.res.in [Physical Research Laboratory, Navrangpura, Ahmedabad—380 009 (India)

    2016-03-01

    We have carried out an extensive multi-wavelength study to investigate the star formation process in the S235 complex. The S235 complex has a spherelike shell appearance at wavelengths longer than 2 μm and harbors an O9.5V type star approximately at its center. A near-infrared extinction map of the complex traces eight subregions (having A{sub V} > 8 mag), and five of them appear to be distributed in an almost regularly spaced manner along the spherelike shell surrounding the ionized emission. This picture is also supported by the integrated {sup 12}CO and {sup 13}CO intensity maps and by Bolocam 1.1 mm continuum emission. The position–velocity analysis of CO reveals an almost semi-ringlike structure, suggesting an expanding H ii region. We find that the Bolocam clump masses increase as we move away from the location of the ionizing star. This correlation is seen only for those clumps that are distributed near the edges of the shell. Photometric analysis reveals 435 young stellar objects (YSOs), 59% of which are found in clusters. Six subregions (including five located near the edges of the shell) are very well correlated with the dust clumps, CO gas, and YSOs. The average values of Mach numbers derived using NH{sub 3} data for three (East 1, East 2, and Central E) out of these six subregions are 2.9, 2.3, and 2.9, indicating these subregions are supersonic. The molecular outflows are detected in these three subregions, further confirming the ongoing star formation activity. Together, all these results are interpreted as observational evidence of positive feedback of a massive star.

  6. Prompt neutron emission and energy balance in 235U(n,f

    Directory of Open Access Journals (Sweden)

    Göök Alf

    2017-01-01

    Full Text Available Investigations of prompt fission neutron (PFN emission are of importance in understanding the fission process in general and the sharing of excitation energy among the fission fragments in particular. Experimental activities at JRC-Geel on PFN emission in response to OECD/NEA nuclear data requests is presented in this contribution. The focus lies on on-going investigations of PFN emission from the reaction 235U(n,f in the region of the resolved resonances taking place at the GELINA facility. For this reaction strong fluctuations of fission fragment mass distributions and mean total kinetic energy have been observed as a function of incident neutron energy in the resonance region. In addition, fluctuations of prompt neutron multiplicities have also been observed. The goal of the present study is to verify the current knowledge of PFN multiplicity fluctuations and to study correlations with fission fragment properties. The experiment employs a scintillation detector array for neutron detection, while fission fragment properties are determined via the double kinetic energy technique using a position sensitive twin ionization chamber. Results on PFN multiplicity correlations with fission fragment properties from the present study show significant differences compared to earlier studies on this reaction, induced by thermal neutrons. Specifically, the total kinetic energy dependence of the neutron multiplicity per fission shows an inverse slope FX1TKE/FX2ν approximately 35% weaker than observed in earlier studies of thermal neutron induced fission on 235U. The inverse slope is related to the energy carried away per emitted neutron and is, thereby, closely connected to the energy balance of the fission reaction. The present result should have strong impact on the modeling of both prompt neutron and prompt γ-ray emission in fission of the 236U compound nucleus.

  7. Study of Relationship Between Neutron Energy and Fission Yields of 95Zr, 140Ba and 147Nd From 235U

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This work measures fission yields of 235U induced by neutrons with energy of thermal, 3.0, 5.0, 5.5, 8.0 and 14.8 MeV. The main purpose is to study the relationship between neutron energy and fission fields of 95Zr,140Ba and 147Nd from 235U by measuring the radioactivity of foil with direct gamma spectrometry. The fission yields induced by fast neutrons are get by fast-thermal-ratio method which based on yields from thermal neutrons, yields by thermal neutron are come from absolute measurement. Since fast-thermal-ratio method eliminates uncertainties of gamma intensity, gamma

  8. Theoretical Model for Volume Fraction of UC, 235U Enrichment, and Effective Density of Final U 10Mo Alloy

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Prabhakaran, Ramprashad [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Joshi, Vineet V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Hu, Shenyang Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); McGarrah, Eric J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL); Lavender, Curt A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Environmental Molecular Sciences Lab. (EMSL)

    2016-04-12

    The purpose of this document is to provide a theoretical framework for (1) estimating uranium carbide (UC) volume fraction in a final alloy of uranium with 10 weight percent molybdenum (U 10Mo) as a function of final alloy carbon concentration, and (2) estimating effective 235U enrichment in the U 10Mo matrix after accounting for loss of 235U in forming UC. This report will also serve as a theoretical baseline for effective density of as-cast low-enriched U 10Mo alloy. Therefore, this report will serve as the baseline for quality control of final alloy carbon content

  9. 238U/235U determinations of some commonly used reference materials and U-bearing accessory minerals (Invited)

    Science.gov (United States)

    Condon, D.; Noble, S.; McLean, N.; Bowring, S. A.

    2009-12-01

    We have determined 238U/235U ratios for a suite of commonly used natural (CRM 112a, SRM 950a, HU-1) and synthetic (IRMM 184 and CRM U500) uranium reference materials in addition to several U-bearing accessory phases (zircon and monazite) by thermal ionisation mass-spectrometry (TIMS) using the IRMM 3636 233U-236U double spike to accurately correct for mass fractionation. The 238U/235U values for the natural uranium reference materials differ, by up to 0.1%, from the widely used ‘consensus’ value (137.88) with all having 238U/235U values less than 137.88. Similarly, initial 238U/235U data from zircon and monazite yield 238U/235U values that are lower than the ‘consensus’ value. The data obtained from U-bearing minerals is used to assess how the uncertainty in the 238U/235U ratio contributes to the systematic discordance observed in 238U/206Pb and 235U/207Pb dates (Mattinson, 2000; Schoene et al., 2006) which has traditionally been wholly attributed to error in the U decay constants. The 238U/235U determinations made on the synthetic reference materials yield results that are considerably more precise and accurate than the certified values (0.02% vs. 0.1% for CRM U500). The calibration of isotopic tracers used for U-daughter geochronology that are partially based upon these reference materials, and the resultant age determinations, will benefit from increased accuracy and precision. Mattinson, J.M., 2000. Revising the “gold standard”—the uranium decay constants of Jaffey et al., 1971. Eos Trans. AGU, Spring Meet. Suppl., Abstract V61A-02. Schoene B., Crowley J.L., Condon D.C., Schmitz M.D., Bowring S.A., 2006, Reassessing the uranium decay constants for geochronology using ID-TIMS U-Pb data. Geochimica et Cosmochimica Acta 70: 426-445

  10. Chromatin and DNA chain fragmentation studies on apoptosis in immune cells induced by 235U and radioprotection of IL—2 or IL—6

    Institute of Scientific and Technical Information of China (English)

    ZhuShou-Peng; ZhangLan-Sheng; 等

    1998-01-01

    The apoptosis in human acute lymphoblastic leukemia cell line Molt-4 cell and macrophage cell line Ana-1 cell are studied after internal irradiation with enriched uranium 235U.The cumulative absorption dose of 235U in cultural cells through different periods are estimated.The fluorescence microscopic observations indicate that Molt-4 and Ana-1 immune cells internally irradiated by 235U displayed significant chromatin fragmentation and marked pyknosis in immune cells nuclei.as well as DNA chain fragmentation and apoptotic bodies formation.It should be noted that DNA chain fragmentation induced by 235U may be inhibited statistically by IL-2(interleukin-2)or IL-6 treatment.

  11. Quantification of {sup 235} U and {sup 226} Ra in soil samples by means of Gamma spectroscopy; Cuantificacion de {sup 235} U y {sup 226} Ra en muestras de suelo por medio de espectrometria gamma

    Energy Technology Data Exchange (ETDEWEB)

    Quintero P, E.; Rojas M, V.P.; Montes M, F.R.; Gaso P, M.I.; Cervantes N, M.L. [Gerencia de Innovacion Tecnologica, A.P. 18-1027, C.P. 11801 Mexico D.F. (Mexico)

    2000-07-01

    In this work it is presented the Gamma Spectroscopy method which is realized in the Environmental Radiological Surveillance Laboratory using the option of deconvolution of a commercial software for the quantification of {sup 235} U and {sup 226} Ra; also is presented the method for the {sup 226} Ra correction activity. (Author)

  12. Study of {sup 235}U excitation in plasma: Isomere experiment at Phebus; Etude de l'excitation de l'{sup 235}U dans un plasma: l'experience isomere sur Phebus

    Energy Technology Data Exchange (ETDEWEB)

    Meot, V.; Baudin, J.-C.; Musolino, N.; Camus, C

    2000-12-01

    We present an experimental study of the excitation of the first isomeric level of {sup 235}U, in plasma created by laser. Several responsible mechanisms for the population of this level are discussed, then an experimental overview is given. The ISOMERE experiment, performed with the PHEBUS laser is presented. Results are compared with theoretical prediction. (authors)

  13. Bonding behavior of 25Cr5MoA/Q235 hot rolled clad plates%25Cr5MoA/Q235钢复合板的结合性能

    Institute of Scientific and Technical Information of China (English)

    陈靖; 佟建国; 任学平

    2007-01-01

    将25Cr5MoA/Q235钢板复合板坯加热到800~1 100 ℃,经保温后轧制1道次,压下量为50%~70%,制成25Cr5MoA/Q235钢热轧复合板试样. 用材料力学性能试验机测试复合板试样复合界面的剪切强度,用光学显微镜和扫描电镜观察界面的组织. 结果表明:当轧制温度在900~1 000 ℃时,有利于25Cr5MoA/Q235钢的复合;道次压下量对25Cr5MoA/Q235钢复合板界面结合强度影响非常大,道次压下量大,有利于形成更多洁净、活化的新生表面,并且可以细化晶粒,提高复合板的结合强度;金属组织中晶粒的梯度变化,有利于提高双金属复合材料的结合强度.

  14. 48 CFR 1552.235-77 - Data Security for Federal Insecticide, Fungicide and Rodenticide Act Confidential Business...

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Data Security for Federal... SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1552.235-77 Data Security for... prescribed in 1535.007-70(d), insert the following clause: Data Security for Federal Insecticide,...

  15. 48 CFR 1552.235-78 - Data Security for Toxic Substances Control Act Confidential Business Information (DEC 1997).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Data Security for Toxic... CONTRACT CLAUSES Texts of Provisions and Clauses 1552.235-78 Data Security for Toxic Substances Control Act...: Data Security for Toxic Substances Control Act Confidential Business Information (DEC 1997)...

  16. Experimental Analysis of OLSR and DSDV Protocols on NS-2.35 in Mobile Ad-Hoc Networks

    Directory of Open Access Journals (Sweden)

    Shelja Sharma

    2015-07-01

    Full Text Available Mobile ad-hoc networks are autonomous networks of intelligent mobile nodes. Designing an efficient routing protocol with goal efficient route establishment is still a burning research issue. Routing protocols are broadly classified into proactive and reactive protocols on the basis of their nature of working. In this paper, we present comparative simulation analysis of two proactive protocols namely, Optimized Link State Routing (OLSR and Destination-Sequenced Distance Vector (DSDV. Simulations have been carried out multiple times using Network Simulator-2.35 (NS-2.35, on random scenario patterns and compared in two environments (OLSR and DSDV by varying the network size and mobility of nodes. We have patched and installed OLSR protocol on NS-2.35 as it's not available as a part of NS-2.35 installation. The simulation results indicate that, OLSR perform better than DSDV protocol for application oriented metrices such as packet delivery fraction, packet loss and end-to-end delay. But, Routing Overheads is significantly consistently higher for OLSR protocol in all the cases considered, which is proven experimentally. Furthermore, based upon the simulation results, work can be done in the direction of improving the performance of the OLSR protocol to make it a choice of proactive protocol for large and denser network.

  17. 40 CFR 270.235 - Options for incinerators, cement kilns, lightweight aggregate kilns, solid fuel boilers, liquid...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Options for incinerators, cement kilns... Technology (MACT) Standards § 270.235 Options for incinerators, cement kilns, lightweight aggregate kilns... incinerator, cement kiln, lightweight aggregate kiln, solid fuel boiler, liquid fuel boiler, or...

  18. RAD001 enhances the potency of BEZ235 to inhibit mTOR signaling and tumor growth.

    Directory of Open Access Journals (Sweden)

    Beat Nyfeler

    Full Text Available The mammalian target of rapamycin (mTOR is regulated by oncogenic growth factor signals and plays a pivotal role in controlling cellular metabolism, growth and survival. Everolimus (RAD001 is an allosteric mTOR inhibitor that has shown marked efficacy in certain cancers but is unable to completely inhibit mTOR activity. ATP-competitive mTOR inhibitors such as NVP-BEZ235 can block rapamycin-insensitive mTOR readouts and have entered clinical development as anti-cancer agents. Here, we show the degree to which RAD001 and BEZ235 can be synergistically combined to inhibit mTOR pathway activation, cell proliferation and tumor growth, both in vitro and in vivo. RAD001 and BEZ235 synergized in cancer lines representing different lineages and genetic backgrounds. Strong synergy is seen in neuronal, renal, breast, lung, and haematopoietic cancer cells harboring abnormalities in PTEN, VHL, LKB1, Her2, or KRAS. Critically, in the presence of RAD001, the mTOR-4EBP1 pathway and tumorigenesis can be fully inhibited using lower doses of BEZ235. This is relevant since RAD001 is relatively well tolerated in patients while the toxicity profiles of ATP-competitive mTOR inhibitors are currently unknown.

  19. Comment on 'The origin of neap-spring tidal cycles' by Erik P. Kvale [Marine Geology 235 5-18

    NARCIS (Netherlands)

    Hoitink, A.J.F.

    2008-01-01

    This paper comments on a recent publication by Erik P. Kvale [Marine Geology 235 (2006) 5–18], who underlines the importance of tropically driven neap–spring cycles. Here it is stressed that tropically driven neap–spring cycles feature a systematic asymmetry, prevalent in both flow velocity time ser

  20. 77 FR 33253 - Regulatory Guide 8.24, Revision 2, Health Physics Surveys During Enriched Uranium-235 Processing...

    Science.gov (United States)

    2012-06-05

    ... COMMISSION Regulatory Guide 8.24, Revision 2, Health Physics Surveys During Enriched Uranium-235 Processing... CONTACT: Gregory Chapman, Uranium Enrichment Branch, Division of Fuel Cycle Safety and Safeguards, Office.... Introduction Revision 2 of Regulatory Guide 8.24, ``Health Physics Surveys During Enriched...

  1. Combined 238U/235U and Pb Isotopics of Planetary Core Material: The Absolute Age of the IVA Iron Muonionalusta

    Science.gov (United States)

    Brennecka, G. A.; Amelin, Y.; Kleine, T.

    2016-08-01

    We report a measured 238U/235U for the IVA iron Muonionalusta. This measured value requires an age correction of ~7 Myr to the previously published Pb-Pb age. This has major implications for our understanding of planetary core formation and cooling.

  2. Radiation-chemical reaction of 2,3,5-triphenyl-tetrazolium chloride in liquid and solid state

    DEFF Research Database (Denmark)

    Kovacs, A.; Wojnarovits, L.; McLaughlin, W.L.

    1996-01-01

    In pulse radiolysis of 2,3,5-triphenyl-tetrazolium chloride (TTC) at around 360 nm fast formation of intermediate tetrazolium radical was observed under both oxidizing and reducing conditions. In the latter case bimolecular formation of formazan, absorbing at around 480 nm, was observed. This rea...

  3. Uranium stable isotope fractionation in the Black Sea: Modern calibration of the 238U/235U paleo-redox proxy

    Science.gov (United States)

    Rolison, John M.; Stirling, Claudine H.; Middag, Rob; Rijkenberg, Micha J. A.

    2017-04-01

    The isotopic compositions of redox-sensitive metals, including uranium (U), in marine sediments have recently emerged as powerful diagnostic tracers of the redox state of the ancient ocean-atmosphere system. Reliable interpretation of sedimentary isotopic information requires a thorough understanding of the environmental controls on isotopic fractionation in modern anoxic environments before being applied to the paleo-record. In this study, the relationship between ocean anoxia and the isotopic fractionation of U was investigated in the water column and sediments of the Black Sea, the world's largest anoxic basin. Paired measurements of 238U/235U and U concentration, supported by other redox parameters, were obtained for water column and sediment samples collected during the 2013 GA04N GEOTRACES expedition to the Black Sea. Removal of U from the water column occurs during the redox transition of soluble U(VI) to relatively insoluble U(IV), resulting in up to 43% of U being removed from solution in euxinic bottom waters. Uranium reduction and removal is accompanied by a progressive shift in 238U/235U towards isotopically light values in the water column as heavier 238U is preferentially exported to sediments over lighter 235U. This gives rise to apparent isotope enrichment factors of ε = -0.63 ± 0.09‰ and ε = -0.84 ± 0.11‰ when U removal is modelled by Rayleigh and closed system equilibrium isotope fractionation, respectively. These ε values fall within the range determined for bacterial U reduction experiments, and together with a striking correlation between the distributions of U and H2S, implicate microbially-mediated U(VI)-U(IV) reduction as the primary mechanism controlling U isotopic shifts in the Black Sea. The 238U/235U of underlying sediments is related to the the 238U/235U of Black Sea bottom waters through the isotope enrichment factor of the U reduction reaction but the relationship between sedimentary and water column 238U/235U is complicated

  4. Reevaluation of the Correlation between Angiotensinogen Gene M235T Polymorphism and Familial Essential Hypertension Using MS-PCR Technique

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective Using mutagenically separated allele-specific polymerase-chain-reaction (MS-PCR) technique to determine the correlation between angiotensinogen gene M235T (Ag TM235T) polymorphism and the onset of familial essential hypertension in the population from Jiangsu and Anhui Provinces. Methods (1) Establish and compare the optimal reaction system of PCR-RFLP and MS-PCR technique to detect AgTM235T polymorphism. (2) All subjects were divided into four groups: 62 patients with both hypertension and familial background (FH), 32 normal persons who had familial background (FNH), 26 persons in control group (N) and 10 patients with hypertension but without familial background (NFH group). The genotype of all subjects was determined by MS-PCR technique.Results (1) The frequency of T allele in PCR-RFLP was 0.5, much lower than 0.95 in MS-PCR, which was demonstrated by DNA sequencing. (2) The TT-genotype and the frequency of T allele (TT/T) in FH and FNH groups were much higher than those in N and NFH groups (0.581/0.766 and 0.563/0.766 vs 0.346/0.577 and 0.40/0.550, P<0.005). (3) Persons developing hypertension in FNH group were much younger than other three groups (28.07±9.72 , P<0.025). Conclusion (1) Compared with PCR-RFLP, MS-PCR is a rapid, simple and reliable technique for detection gene polymorphism of Ag TM25T. (2) In Jiangsu and Anhui area, the present study confirms the observation of a higher frequency of the 235T allele of the angiotensinogen gene in hypertension and identifies individuals with family history. Concerning of the age, we might speculate that the AgTM235T polymorphism is only associated with familial essential hypertension.

  5. 用N235从大洋多金属结核萃铜余液中萃取钴%Study on Selective Extracting Co with N235 from Cu Extraction Raffinate of Ocean Polymetallic Nodules

    Institute of Scientific and Technical Information of China (English)

    王东; 叶绍龙; 周一华; 张茂

    2011-01-01

    研究了用N235从大洋多金属结核熔炼-锈蚀-萃取工艺中所产出的萃铜余液中萃取分离钴的方法.实验结果表明,N235萃取钴效果明显,负载有机相中的钴能被稀酸反萃完全.采用N235萃取和稀酸反萃方法可以把Co(Ⅱ)、Ni(Ⅱ)分离开.从含钴0.85g/L的料液中,按相比VO/VA=1/2,经四级逆流萃取,二级反萃可将钻富集到15.20g/L,萃余液中含钴0.0055g/L,萃余液中Ni/Co高达1 838,反萃液中Co/Ni=1 520,产品质量符合优质工业氯化钴质量要求,钴镍萃取分离效果甚佳,钴的回收率大于98%.%The extraction of Cobalt from the Cu extraction raffinate from melting-rusting-solvent extraction circuit with N235 for Ocean Polymetallic Nodules was studied. The experimental results demonstrate an excellent performance of N235 for Cobalt extraction, while Cobalt can be completely reverse extracted from loaded organic phase by dilute acid. Cobalt ( Ⅱ ) and Ni( Ⅱ ) can be separated from each other by the processes of extraction with N235 and re-extraction with dilute acid. The solution containing 0. 85 g/L of Co at a phase ratio Vo/VA = 1/2 was processed by four-stage coun tercurrent extraction and two-stage re-extraction, cobalt can be concentrated to be 15. 20 g/L. While the extraction raffi nate containing 0.0055 g/L of Co. Ni/Co in the extraction raffinate is up to 1 838 and Co/Ni in re-extraction solution is 1 520. The recovery rate of Co is more than 98% , indicating a good separating result for Co and Ni. The product also meets the standard for high-quality cobalt chloride for industry.

  6. Collinear cluster tripartition as sequential binary fission in the 235U(nth, f ) reaction

    Science.gov (United States)

    Tashkhodjaev, R. B.; Nasirov, A. K.; Scheid, W.

    2011-11-01

    The mechanism leading to the formation of the observed products of the collinear cluster tripartition (CCT) is carried out within the framework of the model based on the dinuclear system concept. The yield of fission products is calculated using the statistical model based on the driving potentials for the fissionable system. The minima of potential energy of the decaying system correspond to the charge numbers of the products which are produced with large probabilities in the sequential fission (partial case of CCT) of the compound nucleus. The realization of this mechanism supposes the asymmetric fission channel as the first stage of sequential mechanism. It is shown that only the use of the driving potential calculated by the binding energies with the shell correction allows us to explain the yield of the true ternary fission products. The theoretical model is applied to research CCT in the reaction 235U( n th, f). Calculations showed that the heavy products of two fission channels of 236U*, 82Ge* + 154Nd* and 86Se* + 150Ce*, can undergo sequential fission forming the CCT products 70Ni, 74, 76Zn, 80Ge and 84Se with relatively large probabilities which can be observed in coincidence with corresponding partner nucleus. The obtained results can explain some of the observed CCT products Ni and Ge in coincidence with the Ge and Se isotopes in the experiments of the FOBOS group in Joint Institute for Nuclear Research.

  7. Frequency of 2,3,5-triphenyltetrazolium chloride (TTC non-reducing bacteria in pasteurized milk

    Directory of Open Access Journals (Sweden)

    Beloti Vanerli

    1999-01-01

    Full Text Available 2,3,5-triphenyltetrazolium chloride (TTC is a dye largely used for enumeration of microbial colonies in solid culture media, being a key component of the dry rehydratable film system used for microbiological analysis of food. This dye is colorless in the oxidized form and red when reduced by microorganisms, due to formation of formazan. In this study, TTC was added to Plate Count Agar (PCA for enumeration of microorganisms in thirty four pasteurized milk samples, with the aim to verify the frequency of microorganisms that are unable to reduce TTC. Milk samples were decimally diluted in saline and pour-plated in PCA plus 0.015% TTC. Colonies were counted after 24h and 48 h of incubation at 35oC. From a total of 50,574 colonies, 19,665 (38.88% did not reduce TTC in 48h. It was observed that 571 (6.36% colonies that were colorless in 24h became red in 48h. From those that didn't reduce TTC in 48h, 233 were purified and Gram stained. 229 (98.71% of them were Gram positive cocci and bacilli. The results show that there is a high percentage of microorganisms unable to reduce TTC in pasteurized milk, which cannot be detected by laboratory procedures based on the formation of red colonies.

  8. AGT M235T genotype/anxiety interaction and gender in the HyperGEN study.

    Directory of Open Access Journals (Sweden)

    Sarah S Knox

    Full Text Available BACKGROUND: Both anxiety and elevated heart rate (HR have been implicated in the development of hypertension. The HyperGen cohort, consisting of siblings with severe and mild hypertension, an age-matched random sample of persons from the same base populations, and unmedicated adult offspring of the hypertensive siblings (N = 1,002 men and 987 women, was analyzed for an association of the angiotenisinogen AGTM235T genotype (TT, MT, MM with an endophenotype, heart rate (HR in high and low anxious groups. METHODOLOGY: The interaction of AGTM genotype with anxiety, which has been independently associated with hypertension, was investigated adjusting for age, hypertension status, smoking, alcohol consumption, beta blocker medication, body mass index, physical activity and hours of television viewing (sedentary life style. PRINCIPAL FINDINGS: Although there was no main effect of genotype on HR in men or women, high anxious men with the TT genotype had high HR, whereas high anxious men with the MM genotype had low HR. In women, HR was inversely associated with anxiety but there was no interaction with genotype. CONCLUSION/SIGNIFICANCE: The results suggest that high anxiety in men with the TT genotype may increase risk for hypertension whereas the MM genotype may be protective in high anxious men. This type of gene x environment interaction may be one reason why genome wide association studies sometimes fail to replicate. The locus may be important only in combination with certain environmental factors.

  9. Characterization of 235U Targets for the Development of a Secondary Neutron Fluence Standard

    Science.gov (United States)

    Heyse, J.; Anastasiou, M.; Eykens, R.; Moens, A.; Plompen, A. J. M.; Schillebeeckx, P.; Sibbens, G.; Vanleeuw, D.; Wynants, R.

    2014-05-01

    The MetroFission project, a Joint Research Project within the European Metrology Research Program (EMRP), aims at addressing a number of metrological problems involved in the design of proposed Generation IV nuclear reactors. As part of this project a secondary neutron fluence standard is being developed and tested at the neutron time-of-flight facility GELINA of the JRC Institute for Reference Materials and Measurements (IRMM). This secondary standard will help to reach the neutron cross section measurement uncertainties required for the design of new generation power plants and fuel cycles. Such a neutron fluence device contains targets for which the neutron induced cross section is considered to be a standard. A careful preparation and characterization of these samples is an essential part of its development. In this framework a set of 235U targets has been produced by vacuum deposition of UF4 on aluminum backings by the target preparation laboratory at IRMM. These targets have been characterized for both their total mass and mass distribution over the sample area.

  10. Experiment and simulation analysis of roll-bonded Q235 steel plate

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, G.; Huang, Q.; Zhou, C.; Zhang, Z.; Ma, L.; Wang, X.

    2016-10-01

    Heavy-gauge Q235 steel plate was roll bonded, and the process was simulated using MARC software. Ultrasonic testing results revealed the presence of cracks and lamination defects in an 80-mm clad steel sheet, especially at the head and tail of the steel plate. There were non-uniform ferrite + pearlite microstructures and unbound areas at a bond interface. Through scanning electron microscopy analysis, long cracks and additional inclusions in the cracks were observed at the interface. A fracture analysis revealed non-uniform inclusions that pervaded the interface. Moreover, MARC simulations demonstrated that there was little equivalent strain at the centre of the slab during the first rolling pass. The equivalent centre increased to 0.5 by the fourth rolling pass. Prior to the final pass, the equivalent strain was not consistent across the thickness direction, preventing bonding interfaces from forming consistent deformation and decreasing the residual stress. The initial rolling reduction rate should not be very small (e.g. 5%) as it is averse to the coordination of rolling deformation. Such rolling processes are averse to the rolling bond. (Author)

  11. Spectroscopic investigation of plasma electrolytic borocarburizing on q235 low-carbon steel

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Run [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Zhenjiang Watercraft College, Zhenjiang 212000, Jiangsu (China); Wang, Bin; Wu, Jie [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Xue, Wenbin, E-mail: xuewb@bnu.edu.cn [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China); Jin, Xiaoyue; Du, Jiancheng; Hua, Ming [Key Laboratory for Beam Technology and Materials Modification of Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Beijing Radiation Center, Beijing 100875 (China)

    2014-12-01

    Highlights: • The plasma discharge behaviors for PEB/C on steels were evaluated by OES. • Electron temperature, concentration, atomic ionization degree were calculated. • The decomposition mechanism of electrolyte and was analyzed. - Abstract: A plasma electrolytic borocarburizing process (PEB/C) in borax electrolyte with glycerin additive was employed to fabricate a hardening layer on Q235 low-carbon steel. Optical emission spectroscopy (OES) was utilized to investigate the spectroscopy characteristics of plasma discharge around the steel during PEB/C process. Some plasma parameters were calculated in terms of OES. The electron temperature and electron concentration in plasma discharge zone is about 3000–12,000 K and 2 × 10{sup 22} m{sup −3}–1.4 × 10{sup 23} m{sup −3}. The atomic ionization degrees of iron, carbon and boron are 10{sup −16}–10{sup −3}, and 10{sup −23}–10{sup −6}, 10{sup −19}–10{sup −4}, respectively, which depend on discharge time. The surface morphology and cross-sectional microstructure of PEB/C hardening layer were observed, and the electrolyte decomposition and plasma discharge behaviors were discussed.

  12. Laser surface treatment of S235JRC carbon steel with Co{sub 2}B nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Simsek, Tuncay [Hacettepe Univ., Ankara (Turkey). Dept. of Physics Engineering; Baris, Mustafa [Eti Maden Works General Management, Ankara (Turkey). Dept. of Technology Development; Akkurt, Adnan [Gazi Univ., Ankara (Turkey). Dept. of Industrial Design Engineering

    2017-06-15

    In this study, Co{sub 2}B nanocrystals, which were synthesized in a planetary type mill by using the mechanochemical method, were pre-coated on the surface of S235JRC low carbon steel substrates, and then the surfaces were clad using a CO{sub 2} laser. In the experiments, laser scan speed was kept constant and laser power was specified as the variable parameter. The microstructure and phases of the coatings were investigated by using X-ray diffractometry, scanning electron microscopy, and optical microscopy. The mechanical properties of the coatings were characterized using micro-hardness, ball-on-disc wear, and scratch testing. The thickness of the coatings depending on the laser power was measured in the range 35-71 μm. The hardness and the wear resistance of the coatings were approximately 3 times higher compared to the base metal due to FeN{sub 0.0760}, Fe{sub 15.1}C, FeCo, and B{sub 2}C{sub 5}N{sub 2} phases of the coatings. The most durable coatings against wear were obtained at 174 W and 220 W laser powers.

  13. Study of prompt-neutron emission in thermal-neutron-induced fission of /sup 235/U

    Energy Technology Data Exchange (ETDEWEB)

    Franklyn, C.B.

    1987-01-01

    An original experiment was performed to measure the angular correlation of fission neutrons from thermal-neutron-induced fission of /sup 235/U, with respect to the light fission fragment direction, as a function of fragment mass division and neutron energy. A Monte Carlo model, with a realistic description of the fission fragment deexcitation process, was developed to simulate the observed neutron-fragment angular correlation data. Simulated neutron-fragment angular correlations displaying similar distributions with respect to the light fragment direction for different forms of neutron emission are shown to exhibit differing distributions when examined as a function of fragment mass division or neutron energy, thus illustrating the sensitivity of the experiment to the forms of neutron emission occurring in fission. A primary conclusion of the investigation was that neutron emission solely from fully accelerated fragments, whether isotropically or anisotropically emitted in the fragment center of mass system, was unable to adequately describe the observed neutron-fragment angular correlations. Simulation of the fission process with some neutron emission before or during fragment acceleration exhibited a closer correspondence with observed phenomena.

  14. 2,3,5-Triphenyl-2H-tetrazol-3-ium iodide

    Directory of Open Access Journals (Sweden)

    Hoong-Kun Fun

    2012-09-01

    Full Text Available The asymmetric unit of the title molecular salt, C19H15N4+·I−, contains four 2,3,5-triphenyl-2H-tetrazol-3-ium cations and five iodide anions, with two of the latter lying on crystallographic inversion centres. In each cation, the tetrazole ring is essentially planar (r.m.s. deviations = 0.004–0.007 Å. The dihedral angles between the tetrazole ring and its three attached benzene rings in the four independent cations are: 12.9 (4, 67.0 (4, 48.1 (4; 20.8 (4, 51.1 (4, 62.3 (4; 11.4 (4, 52.3 (4, 47.3 (4 and 6.0 (4, 85.7 (4, 43.5 (4°. A C—H...I hydrogen bond and C—H...π interactions are observed in the crystal.

  15. Adsorption and corrosion inhibiting effect of riboflavin on Q235 mild steel corrosion in acidic environments

    Energy Technology Data Exchange (ETDEWEB)

    Chidiebere, Maduabuchi A. [Institute of Metal Research, Chinese Academy of Sciences, 62 Wencui Rd, Shenyang 110016 (China); Electrochemistry and Materials Science Research Laboratory, Department of Chemistry, Federal University of Technology Owerri, PMB 1526 Owerri (Nigeria); Oguzie, Emeka E. [Electrochemistry and Materials Science Research Laboratory, Department of Chemistry, Federal University of Technology Owerri, PMB 1526 Owerri (Nigeria); Liu, Li [Institute of Metal Research, Chinese Academy of Sciences, 62 Wencui Rd, Shenyang 110016 (China); Li, Ying, E-mail: liying@imr.ac.cn [Institute of Metal Research, Chinese Academy of Sciences, 62 Wencui Rd, Shenyang 110016 (China); Wang, Fuhui [Institute of Metal Research, Chinese Academy of Sciences, 62 Wencui Rd, Shenyang 110016 (China)

    2015-04-15

    The inhibiting effect of Riboflavin (RF) on Q235 mild steel corrosion in 1 M HCl and 0.5 M H{sub 2}SO{sub 4} at 30 °C temperature was investigated using electrochemical techniques (electrochemical impedance spectroscopy and potentiodynamic polarization). The obtained results revealed that RF inhibited the corrosion reaction in both acidic solutions. Maximum inhibition efficiency values in 1 M HCl and 0.5 M H{sub 2}SO{sub 4} were 83.9% and 71.4%, respectively, obtained for 0.0012 M RF. Polarization data showed RF to be a mixed-type inhibitor, while EIS results revealed that the RF species adsorbed on the metal surface. The adsorption of RF followed Langmuir adsorption isotherm. Atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) studies confirmed the formation of a protective layer adsorbed on the steel surface. Quantum chemical calculations were used to correlate the inhibition ability of RF with its electronic structural parameters. - Highlights: • The inhibitory mechanism was influenced by the nature of acid anions. • RF has reasonable inhibition effect especially in 1 M HCl solution. • Polarization studies showed that RF functioned as a mixed type inhibitor. • Improved surface morphology was observed in the presence of RF.

  16. A `Water Spout' Maser Jet in S235AB-MIR

    CERN Document Server

    Burns, Ross A; Handa, Toshihiro; Omodaka, Toshihiro; Nakagawa, Akiharu; Nagayama, Takumi; Ueno, Yuji

    2015-01-01

    We report on annual parallax and proper motion observations of H2O masers in S235AB-MIR, which is a massive young stellar object in the Perseus Arm. Using multi-epoch VLBI astrometry we measured a parallax of pi = 0.63 +- 0.03 mas, corresponding to a trigonometric distance of D = 1.56+-0.09 kpc, and source proper motion of ( u alpha cos d , u d) = (0.79 +- 0.12, -2.41 +- 0.14) mas/yr. Water masers trace a jet of diameter 15 au which exhibits a definite radial velocity gradient perpendicular to its axis. 3D maser kinematics were well modelled by a rotating cylinder with physical parameters: v_out = 45+-2 km/s, v_rot = 22+-3 km/s, i = 12+-2 degrees, which are the outflow velocity, tangential rotation velocity and line-of-sight inclination, respectively. One maser feature exhibited steady acceleration which may be related to the jet rotation. During our 15 month VLBI programme there were three `maser burst' events caught `in the act' which were caused by the overlapping of masers along the line of sight.

  17. Textile UV detector with 2,3,5-triphenyltetrazolium chloride as an active compound

    Energy Technology Data Exchange (ETDEWEB)

    Kozicki, Marek, E-mail: mkozicki@mitr.p.lodz.p [Institute of Architecture of Textiles, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz (Poland); Sasiadek, Elzbieta [Institute of Architecture of Textiles, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz (Poland)

    2011-05-15

    In this paper, results on the construction of a new flat textile-based UV light dosimeter are reported. As a textile support polyamide woven fabric was chosen, which was surface-modified with 2,3,5-triphenyltetrazolium chloride (TTC). At first, spectrophotometric and dynamic laser light scattering results on the steady-state UV irradiation of aqueous TTC solutions in the presence of oxygen are discussed. If irradiated, TTC converts to the corresponding formazan molecules of red colour. The size and size distribution of the particles is related to the absorbed radiation and pH of the solution. When TTC molecules reside on polyamide textile, UV irradiation causes a colour change from white to deep red. The tinge intensity depends on the absorbed energy per unit surface area. On this basis, the calibration parameters of the detectors, such as dose sensitivity, dose range, quasi-linear dose range, were calculated. Furthermore, the improvement of the dosimeters' resistance to atmospheric conditions was achieved and assessed through washing fastness tests. Finally, the detectors were proved to be adequate for measurements of the 2D distribution of absorbed UV energy. A simple method of UV dose distribution measurements was proposed. The textile-based systems show promise as dosimeters.

  18. Streptomyces lunalinharesii strain 235 shows the potential to inhibit bacteria involved in biocorrosion processes.

    Science.gov (United States)

    Pacheco da Rosa, Juliana; Korenblum, Elisa; Franco-Cirigliano, Marcella Novaes; Abreu, Fernanda; Lins, Ulysses; Soares, Rosângela M A; Macrae, Andrew; Seldin, Lucy; Coelho, Rosalie R R

    2013-01-01

    Four actinomycete strains previously isolated from Brazilian soils were tested for their antimicrobial activity against Bacillus pumilus LF-4 and Desulfovibrio alaskensis NCIMB 13491, bacteria that are well known to be involved in biofilm formation and biocorrosion. Strain 235, belonging to the species Streptomyces lunalinharesii, inhibited the growth of both bacteria. The antimicrobial activity was seen over a wide range of pH, and after treatment with several chemicals and heat but not with proteinase K and trypsin. The antimicrobial substances present in the concentrated supernatant from growth media were partially characterized by SDS-PAGE and extracellular polypeptides were seen. Bands in the size range of 12 to 14.4 kDa caused antimicrobial activity. Transmission electron microscopy of D. alaskensis cells treated with the concentrated supernatant containing the antimicrobial substances revealed the formation of prominent bubbles, the spherical double-layered structures on the cell membrane, and the periplasmic space completely filled with electron-dense material. This is the first report on the production of antimicrobial substances by actinomycetes against bacteria involved in biocorrosion processes, and these findings may be of great relevance as an alternative source of biocides to those currently employed in the petroleum industry.

  19. Streptomyces lunalinharesii Strain 235 Shows the Potential to Inhibit Bacteria Involved in Biocorrosion Processes

    Directory of Open Access Journals (Sweden)

    Juliana Pacheco da Rosa

    2013-01-01

    Full Text Available Four actinomycete strains previously isolated from Brazilian soils were tested for their antimicrobial activity against Bacillus pumilus LF-4 and Desulfovibrio alaskensis NCIMB 13491, bacteria that are well known to be involved in biofilm formation and biocorrosion. Strain 235, belonging to the species Streptomyces lunalinharesii, inhibited the growth of both bacteria. The antimicrobial activity was seen over a wide range of pH, and after treatment with several chemicals and heat but not with proteinase K and trypsin. The antimicrobial substances present in the concentrated supernatant from growth media were partially characterized by SDS-PAGE and extracellular polypeptides were seen. Bands in the size range of 12 to 14.4 kDa caused antimicrobial activity. Transmission electron microscopy of D. alaskensis cells treated with the concentrated supernatant containing the antimicrobial substances revealed the formation of prominent bubbles, the spherical double-layered structures on the cell membrane, and the periplasmic space completely filled with electron-dense material. This is the first report on the production of antimicrobial substances by actinomycetes against bacteria involved in biocorrosion processes, and these findings may be of great relevance as an alternative source of biocides to those currently employed in the petroleum industry.

  20. The AGT Gene M235T Polymorphism and Response of Power-Related Variables to Aerobic Training

    Science.gov (United States)

    Aleksandra, Zarębska; Zbigniew, Jastrzębski; Waldemar, Moska; Agata, Leońska-Duniec; Mariusz, Kaczmarczyk; Marek, Sawczuk; Agnieszka, Maciejewska-Skrendo; Piotr, Żmijewski; Krzysztof, Ficek; Grzegorz, Trybek; Ewelina, Lulińska-Kuklik; Semenova, Ekaterina A.; Ahmetov, Ildus I.; Paweł, Cięszczyk

    2016-01-01

    The C allele of the M235T (rs699) polymorphism of the AGT gene correlates with higher levels of angiotensin II and has been associated with power and strength sport performance. The aim of the study was to investigate whether or not selected power-related variables and their response to a 12-week program of aerobic dance training are modulated by the AGT M235T genotype in healthy participants. Two hundred and one Polish Caucasian women aged 21 ± 1 years met the inclusion criteria and were included in the study. All women completed a 12-week program of low and high impact aerobics. Wingate peak power and total work capacity, 5 m, 10 m, and 30 m running times and jump height and jump power were determined before and after the training programme. All power-related variables improved significantly in response to aerobic dance training. We found a significant association between the M235T polymorphism and jump-based variables (squat jump (SJ) height, p = 0.005; SJ power, p = 0.015; countermovement jump height, p = 0.025; average of 10 countermovement jumps with arm swing (ACMJ) height, p = 0.001; ACMJ power, p = 0.035). Specifically, greater improvements were observed in the C allele carriers in comparison with TT homozygotes. In conclusion, aerobic dance, one of the most commonly practiced adult fitness activities in the world, provides sufficient training stimuli for augmenting the explosive strength necessary to increase vertical jump performance. The AGT gene M235T polymorphism seems to be not only a candidate gene variant for power/strength related phenotypes, but also a genetic marker for predicting response to training. Key points Aerobic dance provides sufficient training stimuli for the improvement of explosive power. The AGT gene M235T polymorphism is associated with individual variation in the change of power-related phenotypes in response to aerobic dance training. The C allele carriers of the AGT gene M235T polymorphism show greater improvements of jump

  1. Microstructure Analysis of Dissimilar Metal CMT Welded Joint of Aluminum Alloy/Q235 Galvanized Steel%铝合金/Q235镀锌钢板异种金属CMT焊接接头组织分析

    Institute of Scientific and Technical Information of China (English)

    庞二元; 马子超; 冯再新

    2015-01-01

    采用ER4043铝硅焊丝和ER5083铝镁焊丝对5083铝合金与Q235镀锌钢板进行CMT焊接实验;通过对焊缝界面组织的SEM和EDS观察分析,研究不同焊丝对5083铝合金和Q235镀锌钢板异种金属焊接接头的影响.结果表明:采用ER4043铝硅焊丝得到的焊接接头性能比采用ER5083铝镁焊丝得到的焊接接头性能更优.

  2. Study on NH3 and CO2 Gas Nitrocarburizing Process of Q235 Steel%Q235钢氨气加二氧化碳气体氮碳共渗工艺的研究

    Institute of Scientific and Technical Information of China (English)

    黄元盛; 邹敢锋; 袁叔贵

    2000-01-01

    研究了Q235钢用NH3+CO2进行气体氮碳共渗工艺,找到了最佳工艺参数.同时与NH3+CH3OH气体氮碳共渗进行对比,表明NH3+CO2气体氮碳共渗比NH3+CH3OH气体氮碳共渗的渗层质量好.

  3. 235UF6和238UF6同位素分子共振能量转移研究%Resonance Energy Transfer Study on 235 UF6 and 238 UF6 Isotopic Molecules

    Institute of Scientific and Technical Information of China (English)

    张云光; 宋海洋

    2014-01-01

    本文利用长程力碰撞理论计算了235 U F6和238 U F6同位素分子间ν3振动能量的近共振碰撞转移过程,得到了不同温度下共振函数随能量差变化的曲线,发现共振函数的宽度随温度的升高而增大。计算了不同温度下共振转移几率和共振转移速率,发现它们随温度的升高而减小。可见,235 U F6和238 U F6同位素分子的平动会降低其共振转移几率和共振转移速率,这为激光光化学法分离铀同位素提供了理论依据。%The resonant energy transfer process of ν3 vibration energy for 235 UF6 and 238 UF6 isotopic molecules was studied by long distance collision theory ,and the curves of resonance function with energy difference were obtained .The calculated result shows that the width of resonance function rises with the increase of temperature .In addition , the resonant transfer probability and rate were calculated under different temperatures , and it is found that they decrease with the increase of temperature and the translation of 235 UF6 and 238 UF6 isotopic molecules can reduce the resonant transfer probability and rate .These values can provide a reference for actual separation of uranium isotopes .

  4. Reserch on the Influence of Pesticide to Q235 Steel Microbilogical Corrosion%杀虫剂对Q235钢微生物腐蚀影响的研究

    Institute of Scientific and Technical Information of China (English)

    赵琳琳; 赵平; 孙成; 许进

    2011-01-01

    The effect of sulfate reducing bacterial ( SRB) on corrosion of carbon steel in the soil with different concentration of imidacloprid was studied by the methods of bacterial analyses, electrochemical impedance spectroscopy and scanning electron microscopy ( SEM). The results show that the quantity of SRB decreases with the increasing concentration of imidacloprid, indicating the addition of imidacloprid may inhibit the growth of SRB. The corrosion rate of Q235 steel in soil slows down due to imidacloprid addition.%利用微生物分析、交流阻抗测试技术,扫描电镜等方法,研究了在不同吡虫啉浓度下的同一类型土壤中硫酸盐还原菌(SRB)对Q235钢腐蚀的影响.结果表明:随着吡虫啉浓度的增加,SRB的数量逐渐减少,说明吡虫啉的加入对SRB的生长有抑制作用,可降低对Q235钢的腐蚀速率.

  5. Experiment and simulation analysis of roll-bonded Q235 steel plate

    Directory of Open Access Journals (Sweden)

    Zhao, Guanghui

    2016-06-01

    Full Text Available Heavy-gauge Q235 steel plate was roll bonded, and the process was simulated using MARC software. Ultrasonic testing results revealed the presence of cracks and lamination defects in an 80-mm clad steel sheet, especially at the head and tail of the steel plate. There were non-uniform ferrite + pearlite microstructures and unbound areas at a bond interface. Through scanning electron microscopy analysis, long cracks and additional inclusions in the cracks were observed at the interface. A fracture analysis revealed non-uniform inclusions that pervaded the interface. Moreover, MARC simulations demonstrated that there was little equivalent strain at the centre of the slab during the first rolling pass. The equivalent centre increased to 0.5 by the fourth rolling pass. Prior to the final pass, the equivalent strain was not consistent across the thickness direction, preventing bonding interfaces from forming consistent deformation and decreasing the residual stress. The initial rolling reduction rate should not be very small (e.g. 5% as it is averse to the coordination of rolling deformation. Such rolling processes are averse to the rolling bond.Planchas de acero Q235 de espesor grueso se unieron mediante laminación y el proceso fue simulado numéricamente utilizando el programa de cálculo MARC. Los resultados obtenidos en ensayos mediante ultrasonidos revelaron la presencia de grietas y defectos en la laminación en una plancha de acero revestido de 80 mm, especialmente en el comienzo y final de la plancha. La microestructura consistía en ferrita+perlita y desunión en la interfase de unión. Mediante análisis por microscopía electrónica de barrido se observó que la interfase contenía grietas con inclusiones. Un análisis de la fractura reveló la presencia de inclusiones no uniformes en la interfase. Además, los datos de simulación utilizando el programa MARC demostraron que había poca tensión equivalente en el centro de la plancha

  6. Perancangan Dan Analisis Antena Mikrostrip Mimo Circular Pada Frekuensi 2.35 GHz Untuk Aplikasi LTE

    Directory of Open Access Journals (Sweden)

    Imam M.P Budi

    2017-02-01

    Full Text Available LTE (long Term Evolution merupakan teknologi komunikasi wireless generasi keempat yang saat ini sedang mengalami perkembangan. Salah satu perangkat yang sangat dibutuhkan pada teknologi tersebut adalah antenna. Teknik yang digunakan adalah teknik MIMO. Teknik MIMO menggunakan multiantena baik di sisi transmitter maupun di sisi receiver dengan koefisien korelasi di bawah 0.2. Untuk menghasilkan nilai koefisien korelasi di bawah 0.2, antena menggunakan ?/2 untuk jarak antar dua antena. Perancangan dan realisasi antena pada skripsi ini dipergunakan untuk aplikasi LTE yang bekerja pada frekuensi 2.3 GHz sampai 2.4 GHz. Simulasi antena menunjukkan frekuensi kerja yang direncanakan yaitu antara 2.3 GHz – 2.4 GHz, memiliki Return Loss -38.582 dB dan VSWR 1.0238 pada frekuensi tengah 2.350 MHz, gain sebesar 4.332 dBi. Hasil pengukuran antena satu terdapat pergeseran frekuensi dari 2.300 MHz - 2.400 MHz menjadi 2.310 - 2.384 MHz, antena  ini memiliki  Return  Loss -35.476 dB dan VSWR 1.034. Bandwidth 74 Mhz. Untuk antena dua terdapat pergeseran frekuensi menjadi 2.310 - 2.382 MHz, dengan Return  Loss -33.637 dB  dan VSWR  1.042. Bandwidth 72 MHz. Pada frekuensi 2.35 GHz gain sebesar 8 dBi dengan pola radiasi unidirectional dan polarisasi elips. Dari perancangan dan analisis tersebut, maka antena ini dapat digunakan sebagai antena teknologi LTE

  7. MR imaging of intracranial hemorrhage in neonates and infants at 2.35 Tesla.

    Science.gov (United States)

    Zuerrer, M; Martin, E; Boltshauser, E

    1991-01-01

    The variations of the relative signal intensity and the time dependent changing contrast of intracranial hemorrhages on high-field spin-echo magnetic resonance images (MRI) were studied in 28 pediatric patients. For T1-weighted images, a repetition time (TR) of 500 ms and an echo time (TE) of 30 or 23 ms was used. The corresponding times for T2-weighted images were TR 3000 ms and TE 120 ms. Intracranial hematomas, less than 3 days old, were iso- to mildly hypointense on short TR/TE scans and markedly hypointense on long TR/TE scans (acute stage). In the following four days the signal of the hematomas became hyperintense on short TR/TE scans, beginning in the periphery and proceeding towards the center. On long TR/TE scans the signal remained markedly hypointense (early subacute stage). 7-14 days old hematomas were of high signal intensity on short TR/TE scans. On long TR/TE scans they appeared hypointense in the center and hyperintense in the periphery (late subacute stage). By the end of the second week the hematomas were of high signal intensity on all pulse sequences (chronic stage). Chronic hematomas were surrounded by a parenchymal rim of hypointensity on long TR/TE scans. 28 neonates and infants (with 11 follow-up examinations) of 31.5-70.6 weeks postconceptional age (PCA), with an intracranial hemorrhage were examined. The etiologies of the hemorrhages were: asphyxia (17 cases), brain infarct (2), thrombocytopenia (1), clotting disorder (1) and unknown origin (7). The aim of this study was to describe the appearance of intracranial hemorrhages in neonates and infants with MRI at 2.35 Tesla using spine-cho sequences.

  8. Streptomyces lunalinharesii 235 prevents the formation of a sulfate-reducing bacterial biofilm.

    Science.gov (United States)

    Rosa, Juliana Pacheco da; Tibúrcio, Samyra Raquel Gonçalves; Marques, Joana Montezano; Seldin, Lucy; Coelho, Rosalie Reed Rodrigues

    2016-01-01

    Streptomyces lunalinharesii strain 235 produces an antimicrobial substance that is active against sulfate reducing bacteria, the major bacterial group responsible for biofilm formation and biocorrosion in petroleum reservoirs. The use of this antimicrobial substance for sulfate reducing bacteria control is therefore a promising alternative to chemical biocides. In this study the antimicrobial substance did not interfere with the biofilm stability, but the sulfate reducing bacteria biofilm formation was six-fold smaller in carbon steel coupons treated with the antimicrobial substance when compared to the untreated control. A reduction in the most probable number counts of planktonic cells of sulfate reducing bacteria was observed after treatments with the sub-minimal inhibitory concentration, minimal inhibitory concentration, and supra-minimal inhibitory concentration of the antimicrobial substance. Additionally, when the treated coupons were analyzed by scanning electron microscopy, the biofilm formation was found to be substantially reduced when the supra-minimal inhibitory concentration of the antimicrobial substance was used. The coupons used for the biofilm formation had a small weight loss after antimicrobial substance treatment, but corrosion damage was not observed by scanning electron microscopy. The absence of the dsrA gene fragment in the scraped cell suspension after treatment with the supra-minimal inhibitory concentration of the antimicrobial substance suggests that Desulfovibrio alaskensis was not able to adhere to the coupons. This is the first report on an antimicrobial substance produced by Streptomyces active against sulfate reducing bacteria biofilm formation. The application of antimicrobial substance as a potential biocide for sulfate reducing bacteria growth control could be of great interest to the petroleum industry.

  9. Streptomyces lunalinharesii 235 prevents the formation of a sulfate-reducing bacterial biofilm

    Directory of Open Access Journals (Sweden)

    Juliana Pacheco da Rosa

    Full Text Available ABSTRACT Streptomyces lunalinharesii strain 235 produces an antimicrobial substance that is active against sulfate reducing bacteria, the major bacterial group responsible for biofilm formation and biocorrosion in petroleum reservoirs. The use of this antimicrobial substance for sulfate reducing bacteria control is therefore a promising alternative to chemical biocides. In this study the antimicrobial substance did not interfere with the biofilm stability, but the sulfate reducing bacteria biofilm formation was six-fold smaller in carbon steel coupons treated with the antimicrobial substance when compared to the untreated control. A reduction in the most probable number counts of planktonic cells of sulfate reducing bacteria was observed after treatments with the sub-minimal inhibitory concentration, minimal inhibitory concentration, and supra-minimal inhibitory concentration of the antimicrobial substance. Additionally, when the treated coupons were analyzed by scanning electron microscopy, the biofilm formation was found to be substantially reduced when the supra-minimal inhibitory concentration of the antimicrobial substance was used. The coupons used for the biofilm formation had a small weight loss after antimicrobial substance treatment, but corrosion damage was not observed by scanning electron microscopy. The absence of the dsrA gene fragment in the scraped cell suspension after treatment with the supra-minimal inhibitory concentration of the antimicrobial substance suggests that Desulfovibrio alaskensis was not able to adhere to the coupons. This is the first report on an antimicrobial substance produced by Streptomyces active against sulfate reducing bacteria biofilm formation. The application of antimicrobial substance as a potential biocide for sulfate reducing bacteria growth control could be of great interest to the petroleum industry.

  10. $\\gamma$-ray energy spectra and multiplicities from the neutron-induced fission of $^{235}$U using STEFF

    CERN Multimedia

    An experiment is proposed to use the STEFF spectrometer at n_TOF to study fragment $\\gamma$-correlations following the neutron-induced fission of $^{235}$U. The STEFF array of 12 NaI detectors will allow measurements of the single $\\gamma$-energy, the $\\gamma$ multiplicity, and the summed $\\gamma$energy distributions as a function of the mass and charge split, and deduced excitation energy in the fission event. These data will be used to study the origin of fission-fragment angular momenta, examining angular distribution eects as a function of incident neutron energy. The principal application of this work is in meeting the NEA high-priority request for improved $\\gamma$ray data from $^{235}$U(n; F). To improve the detection rate and expand the range of detection angles, STEFF will be modied to include two new ssion-fragment detectors each at 45 to the beam direction.

  11. 238U and 235U isotope fractionation upon oxidation of uranium-bearing rocks by fracture waters

    Science.gov (United States)

    Chernyshev, I. V.; Golubev, V. N.; Chugaev, A. V.; Mandzhieva, G. V.

    2016-10-01

    The variations in 238U/235U values accompanying mobilization of U by fracture waters from uranium-bearing rocks, in which U occurs as a fine impregnation of oxides and silicates, were studied by the high-precision (±0.07‰) MC-ICP-MS method. Transition of U into the aqueous phase in the oxidized state U(VI) is accompanied by its isotope fractionation with enrichment of dissolved U(VI) in the heavy isotope 238U up to 0.32‰ in relation to the composition of the solid phases. According to the sign, this effect is consistent with the tendency of the behavior of 238U and 235U upon interaction of river waters with rocks of the catchment areas [11] and with the effect observed during oxidation of uraninite by the oxygen-bearing NaHCO3 solution [12].

  12. PROPERTIES AND BEHAVIOR OF 238PU RELEVANT TO DECONTAMINATION OF BUILDING 235-F

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, A.; Kane, M.

    2009-11-24

    This report was prepared to document the physical, chemical and radiological properties of plutonium oxide materials that were processed in the Plutonium Fuel Form Facility (PuFF) in building 235-F at the Savannah River Plant (now known as the Savannah River Site) in the late 1970s and early 1980s. An understanding of these properties is needed to support current project planning for the safe and effective decontamination and deactivation (D&D) of PuFF. The PuFF mission was production of heat sources to power Radioisotope Thermoelectric Generators (RTGs) used in space craft. The specification for the PuO{sub 2} used to fabricate the heat sources required that the isotopic content of the plutonium be 83 {+-} 1% Pu-238 due to its high decay heat of 0.57 W/g. The high specific activity of Pu-238 (17.1 Ci/g) due to alpha decay makes this material very difficult to manage. The production process produced micron-sized particles which proved difficult to contain during operations, creating personnel contamination concerns and resulting in the expenditure of significant resources to decontaminate spaces after loss of material containment. This report examines high {sup 238}Pu-content material properties relevant to the D&D of PuFF. These relevant properties are those that contribute to the mobility of the material. Physical properties which produce or maintain small particle size work to increase particle mobility. Early workers with {sup 238}PuO{sub 2} felt that, unlike most small particles, Pu-238 oxide particles would not naturally agglomerate to form larger, less mobile particles. It was thought that the heat generated by the particles would prevent water molecules from binding to the particle surface. Particles covered with bound water tend to agglomerate more easily. However, it is now understood that the self-heating effect is not sufficient to prevent adsorption of water on particle surfaces and thus would not prevent agglomeration of particles. Operational

  13. Substituted piperazines as nootropic agents: 2- or 3-phenyl derivatives structurally related to the cognition-enhancer DM235.

    Science.gov (United States)

    Guandalini, Luca; Martino, Maria Vittoria; Di Cesare Mannelli, Lorenzo; Bartolucci, Gianluca; Melani, Fabrizio; Malik, Ruchi; Dei, Silvia; Floriddia, Elisa; Manetti, Dina; Orlandi, Francesca; Teodori, Elisabetta; Ghelardini, Carla; Romanelli, Maria Novella

    2015-04-15

    A series of 2-phenyl- or 3-phenyl piperazines, structurally related to DM235 and DM232, two potent nootropic agents, have been prepared and tested in the mouse passive-avoidance test, to assess their ability to revert scopolamine-induced amnesia. Although the newly synthesized molecules were less potent than the parent compounds, some useful information has been obtained from structure-activity relationships. A small but significant enantioselectivity has been found for the most potent compound 5a.

  14. The AGT Gene M235T Polymorphism and Response of Power-Related Variables to Aerobic Training

    Directory of Open Access Journals (Sweden)

    Zarębska Aleksandra, Jastrzębski Zbigniew, Moska Waldemar, Leońska-Duniec Agata, Kaczmarczyk Mariusz, Sawczuk Marek, Maciejewska-Skrendo Agnieszka, Żmijewski Piotr, Ficek Krzysztof, Trybek Grzegorz, Lulińska-Kuklik Ewelina, Ekaterina A. Semenova, Ildus I. Ahmetov, Cięszczyk Paweł

    2016-12-01

    Full Text Available The C allele of the M235T (rs699 polymorphism of the AGT gene correlates with higher levels of angiotensin II and has been associated with power and strength sport performance. The aim of the study was to investigate whether or not selected power-related variables and their response to a 12-week program of aerobic dance training are modulated by the AGT M235T genotype in healthy participants. Two hundred and one Polish Caucasian women aged 21 ± 1 years met the inclusion criteria and were included in the study. All women completed a 12-week program of low and high impact aerobics. Wingate peak power and total work capacity, 5 m, 10 m, and 30 m running times and jump height and jump power were determined before and after the training programme. All power-related variables improved significantly in response to aerobic dance training. We found a significant association between the M235T polymorphism and jump-based variables (squat jump (SJ height, p = 0.005; SJ power, p = 0.015; countermovement jump height, p = 0.025; average of 10 countermovement jumps with arm swing (ACMJ height, p = 0.001; ACMJ power, p = 0.035. Specifically, greater improvements were observed in the C allele carriers in comparison with TT homozygotes. In conclusion, aerobic dance, one of the most commonly practiced adult fitness activities in the world, provides sufficient training stimuli for augmenting the explosive strength necessary to increase vertical jump performance. The AGT gene M235T polymorphism seems to be not only a candidate gene variant for power/strength related phenotypes, but also a genetic marker for predicting response to training.

  15. The Prompt Fission Neutron Spectrum of 235U for Einc 0.7-5.0 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Gomez, Jaime A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Devlin, Matthew James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Haight, Robert Cameron [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); O' Donnell, John M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lee, Hye Young [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mosby, Shea Morgan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Taddeucci, Terry Nicholas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kelly, Keegan John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Fotiadis, Nikolaos [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Neudecker, Denise [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); White, Morgan Curtis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Talou, Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rising, Michael Evan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Solomon, Clell Jeffrey Jr. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wu, Ching-Yen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bucher, Brian Michael [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Buckner, Matthew Quinn [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Henderson, Roger Alan [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-03-23

    The Chi-Nu experiment aims to accurately measure the prompt fission neutron spectrum (PFNS) for the major actinides. At the Los Alamos Neutron Science Center (LANSCE), fission can be induced using the white neutron source. Using a two arm time of flight (T.O.F) technique; Chi-Nu presents a preliminary result of the low energy component of the 235U PFNS measured using an array of 22-Lithium glass scintillators.

  16. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010

    DEFF Research Database (Denmark)

    Lozano, Rafael; Naghavi, Mohsen; Foreman, Kyle

    2012-01-01

    Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates. In the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010), we aimed to estimate annual deaths for the world and 21...... regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex....

  17. Fission Fragment Angular Distribution measurements of 235U and 238U at CERN n_TOF facility

    Directory of Open Access Journals (Sweden)

    Leal-Cidoncha E.

    2016-01-01

    In order to measure the FFAD of neutron-induced reactions, a fission detection setup based on parallel-plate avalanche counters (PPACs has been developed and successfully used at the CERN-n_TOF facility. In this work, we present the preliminary results on the analysis of new 235U(n,f and 238U(n,f data in the extended energy range up to 200 MeV compared to the existing experimental data.

  18. Qualitative and quantitative event-specific PCR detection methods for oxy-235 canola based on the 3' integration flanking sequence.

    Science.gov (United States)

    Yang, Litao; Guo, Jinchao; Zhang, Haibo; Liu, Jia; Zhang, Dabing

    2008-03-26

    As more genetically modified plant events are approved for commercialization worldwide, the event-specific PCR method has become the key method for genetically modified organism (GMO) identification and quantification. This study reveals the 3' flanking sequence of the exogenous integration of Oxy-235 canola employing thermal asymmetric interlaced PCR (TAIL-PCR). On the basis of the revealed 3' flanking sequence, PCR primers and TaqMan probe were designed and qualitative and quantitative PCR assays were established for Oxy-235 canola. The specificity and limits of detection (LOD) and quantification (LOQ) of these two PCR assays were validated to as low as 0.1% for the relative LOD of qualitative PCR assay; the absolute LOD and LOQ were low to 10 and 20 copies of canola genomic DNA in quantitative PCR assay, respectively. Furthermore, ideal quantified results were obtained in the practical canola sample detection. All of the results indicate that the developed qualitative and quantitative PCR methods based on the revealed 3' integration flanking sequence are suitable for GM canola Oxy-235 identification and quantification.

  19. The microRNA miR-235 couples blast-cell quiescence to the nutritional state.

    Science.gov (United States)

    Kasuga, Hidefumi; Fukuyama, Masamitsu; Kitazawa, Aya; Kontani, Kenji; Katada, Toshiaki

    2013-05-23

    The coordination of stem- and blast-cell behaviours, such as self-renewal, differentiation and quiescence, with physiological changes underlies growth, regeneration and tissue homeostasis. Germline stem and somatic blast cells in newly hatched Caenorhabditis elegans larvae can suspend postembryonic development, which consists of diverse cellular events such as migration, proliferation and differentiation, until the nutritional state becomes favourable (termed L1 diapause). Although previous studies showed that the insulin/insulin-like growth factor (IGF) signalling (IIS) pathway regulates this developmental quiescence, the detailed mechanism by which the IIS pathway enables these multipotent cells to respond to nutrient availability is unknown. Here we show in C. elegans that the microRNA (miRNA) miR-235, a sole orthologue of mammalian miR-92 from the oncogenic miR-17-92 cluster, acts in the hypodermis and glial cells to arrest postembryonic developmental events in both neuroblasts and mesoblasts. Expression of mir-235 persists during L1 diapause, and decreases upon feeding in a manner dependent on the IIS pathway. Upregulation of one of the miR-235 targets, nhr-91, which encodes an orthologue of mammalian germ cell nuclear factor, is responsible for defects caused by loss of the miRNA. Our findings establish a novel role of a miR-92 orthologue in coupling blast-cell behaviours to the nutritional state.

  20. Primary study on holdup measurement of 235U in pipe using γ-ray spectrometry and Monte Carlo simulation

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The pipe holdup measurement is very important for decommissioning nuclear facilities and nuclear-material control and accounting. The absolute detection efficiencies (εsp) of full-energy γ rays peak under different source density distribution function have been simulated using the Monte Carlo (MC) software, and the counting rates (n0) of the characteristic γ rays have been measured using the γ spectrometer followed by the calculation of the holdup. The holdup is affected by the energy of γ rays, distance at which they are detected, pipe material, thickness,and source distribution of pipe, especially source distribution at a short distance. The comparative test of 235U reference materials on the inner wall of Fe and A1 pipes (the total mass of 235U is 44.6 mg and 222.8 mg, respectively) have been accomplished using this method. The determined result of 235U is 43.2mg (U0.95rel=5.4%) and 216.2mg (U0.95rel= 3.2%), respectively, which are in accordance with the reference values.

  1. Calculation of resonance self-shielding for {sup 235}U from 0 to 2250 eV

    Energy Technology Data Exchange (ETDEWEB)

    Leal, L.C.; Larson, N.M.; Derrien, H. [Oak Ridge National Lab., TN (United States); Santos, G.R. [Cidade Univ., Rio de Janeiro (Brazil). Inst. de Engenharia Nuclear

    1998-08-01

    Over the years, the evaluated {sup 235}U cross sections in the resolved energy range have been extensively revised. A major accomplishment was the first evaluation released to the ENDF/B-VI library. In that evaluation, the low energy range bound was lowered to 10{sup {minus}5} eV, and the upper limit raised to 2,250 eV. Several high-resolution measurements in conjunction with the Bayesian computer code SAMMY were used to perform the analysis of the {sup 235}U resonance parameters. SAMMY uses the Reich-Moore formalism, which is adequate for representing neutron cross sections of fissile isotopes, and a generalized least-squares (Bayes) technique for determining the energy-dependence of the neutron cross sections. Recently a re-evaluation of the {sup 235}U cross section in the resolved resonance region was completed. This evaluation has undergone integral tests in various laboratories throughout the USA and abroad. The evaluation has been accepted for inclusion in ENDF/B-VI release 5. The intent of this work is to present results of calculations of self-shielded fission rates carried out with these resonance parameters and to compare those fission rates with experimental data. Results of this comparison study provide an assessment of the resonance parameters with respect to the calculation of self-shielded group cross sections.

  2. 235U Determination using In-Beam Delayed Neutron Counting Technique at the NRU Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Andrews, M. T. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bentoumi, G. [Canadian Nuclear Labs., Chalk River, ON (Canada); Corcoran, E. C. [Royal Military College of Canada, Kingston, ON (United States); Dimayuga, I. [Canadian Nuclear Labs., Chalk River, ON (Canada); Kelly, D. G. [Royal Military College of Canada, Kingston, ON (United States); Li, L. [Canadian Nuclear Labs., Chalk River, ON (Canada); Sur, B. [Canadian Nuclear Labs., Chalk River, ON (Canada); Rogge, R. B. [Canadian Nuclear Labs., Chalk River, ON (Canada)

    2015-11-17

    This paper describes a collaborative effort that saw the Royal Military College of Canada (RMC)’s delayed neutron and gamma counting apparatus transported to Canadian Nuclear Laboratories (CNL) for use in the neutron beamline at the National Research Universal (NRU) reactor. Samples containing mg quantities of fissile material were re-interrogated, and their delayed neutron emissions measured. This collaboration offers significant advantages to previous delayed neutron research at both CNL and RMC. This paper details the determination of 235U content in enriched uranium via the assay of in-beam delayed neutron magnitudes and temporal behavior. 235U mass was determined with an average absolute error of ± 2.7 %. This error is lower than that obtained at RMCC for the assay of 235U content in aqueous solutions (3.6 %) using delayed neutron counting. Delayed neutron counting has been demonstrated to be a rapid, accurate, and precise method for special nuclear material detection and identification.

  3. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 has a therapeutic potential and sensitizes cisplatin in nasopharyngeal carcinoma.

    Directory of Open Access Journals (Sweden)

    Fen Yang

    Full Text Available Phosphoinositide 3-kinase (PI3K/AKT/mammalian target of rapamycin inhibitor (mTOR pathway is often constitutively activated in human tumor cells and thus has been considered as a promising drug target. To ascertain a therapeutical approach of nasopharyngeal carcinoma (NPC, we hypothesized NVP-BEZ235, a novel and potent imidazo[4,5-c] quinolone derivative, that dually inhibits both PI3K and mTOR kinases activities, had antitumor activity in NPC. Expectedly, we found that NVP-BEZ235 selectively inhibited proliferation of NPC cells rather than normal nasopharyngeal cells using MTT assay. In NPC cell lines, with the extended exposure, NVP-BEZ235 selectively inhibited proliferation of NPC cells harboring PIK3CA mutation, compared to cells with wild-type PIK3CA. Furthermore, exposure of NPC cells to NVP-BEZ235 resulted in G1 growth arrest by Propidium iodide uptake assay, reduction of cyclin D1and CDK4, and increased levels of P27 and P21 by Western blotting, but negligible apoptosis. Moreover, we found that cisplatin (CDDP activated PI3K/AKT and mTORC1 pathways and NVP-BEZ235 alleviated the activation by CDDP through dually targeting PI3K and mTOR kinases. Also, NVP-BEZ235 combining with CDDP synergistically inhibited proliferation and induced apoptosis in NPC cells. In CNE2 and HONE1 nude mice xenograft models, orally NVP-BEZ235 efficiently attenuated tumor growth with no obvious toxicity. In combination with NVP-BEZ235 and CDDP, there was dramatic synergy in shrinking tumor volumes and inducing apoptosis through increasing Noxa, Bax and decreasing Mcl-1, Bcl-2. Based on the above results, NVP-BEZ235, which has entered phase I/II clinical trials in patients with advanced solid tumors, has a potential as a monotherapy or in combination with CDDP for NPC treatment.

  4. BEZ235 (PIK3/mTOR inhibitor Overcomes Pazopanib Resistance in Patient-Derived Refractory Soft Tissue Sarcoma Cells

    Directory of Open Access Journals (Sweden)

    Hee Kyung Kim

    2016-06-01

    Full Text Available BACKGROUND: Although pazopanib treatment has become the standard chemotherapy in salvage setting for metastatic sarcoma patients, most patients progress after pazopanib treatment in 4 to 6 months. After failure to pazopanib, patients have limited options for treatment. Therefore, subsequent therapy in patients who failed to pazopanib is urgently needed and the use of patient derived cells or patient derived tumors for accompanying testing with various pharmacological inhibitors could offer additional treatment options for these patients. METHODS: Patient derived tumor cells were collected from ascites at the time of progression to pazopanib and a 13-drug panel was tested for drug sensitivity. We confirmed the results using in vitro cell viability assay and immunoblot assay. We also performed the genomic profiling of PDX model. RESULTS: The growth of patient derived tumor cells was significantly reduced by exposure to 1.0 μM AZD2014 compared with control (control versus AZD2014, mean growth = 100.0% vs 16.04%, difference = 83.96%, 95% CI = 70.01% to 97.92%, P = .0435. Similarly, 1.0 μM BEZ235 profoundly inhibited tumor cell growth in vitro when compared to control (control versus BEZ235, mean growth = 100.0% vs 7.308%, difference = 92.69%, 95% CI = 78.87% to 106.5%, P < .0001. Despite the presence of CDK4 amplification in the patient-derived tumor cells, LEE011 did not considerably inhibit cell proliferation when compared with control (control vs LEE011, mean growth = 100.0% vs 80.23%, difference = 19.77%, 95% CI = 1.828% to 37.72%, P = .0377. The immunoblot analysis showed that BEZ235 treatment decreased pAKT, pmTOR and pERK whereas AZD2014 decreased only pmTOR. CONCLUSION: Taken together, upregulation of mTOR/AKT pathway in sarcoma patient derived cells was considerably inhibited by the treatment of AZD2014 and BEZ235 with downregulation of AKT pathway (greater extent for BEZ235. These molecules may be considered as treatment option in STS

  5. Micro-image analysis in the diffusion-bonded zone of Fe3Al/Q235 carbon steel dissimilar materials

    Indian Academy of Sciences (India)

    Wang Juan; Li Yajiang; Wu Huiqiang; Ren Jiangwei

    2002-10-01

    The chemical composition of the second phase precipitation in the vacuum diffusion-bonded zone of Fe3Al intermetallic compound and Q235 carbon steel was analysed by means of electron probe microanalyser (EPMA). The relative content of the second phase precipitation and grain size was evaluated through a micro-image analyser. The percentage of Fe and Al content in the diffusion zone was measured by EPMA. The results indicated that the relative content of the second phase precipitation rich in carbon and chromium at the Fe3Al/Q235 interface was much higher. With the transition from Fe3Al intermetallic compound to Q235 carbon steel across Fe3Al/Q235 interface, the grain diameter decreased from 250 m to 112 m, Al atom content decreased from 27% to 15%, while Fe atom content increased from 76% to 96%.

  6. Adsorptive removal of methyl orange and methylene blue from aqueous solution with a metal-organic framework material, iron terephthalate (MOF-235).

    Science.gov (United States)

    Haque, Enamul; Jun, Jong Won; Jhung, Sung Hwa

    2011-01-15

    An iron terephthalate (MOF-235), one of the metal-organic frameworks (MOFs), has been used for the removal of harmful dyes (anionic dye methyl orange (MO) and cationic dye methylene blue (MB)) from contaminated water via adsorption. The adsorption capacities of MOF-235 are much higher than those of an activated carbon. The performance of MOF-235 having high adsorption capacity is remarkable because the MOF-235 does not adsorb nitrogen at liquid nitrogen temperature. Based on this study, MOFs, even if they do not adsorb gases, can be suggested as potential adsorbents to remove harmful materials in the liquid phase. Adsorption of MO and MB at various temperatures shows that the adsorption is a spontaneous and endothermic process and that the entropy increases (the driving force of the adsorption) with adsorption of MO and MB. Copyright © 2010 Elsevier B.V. All rights reserved.

  7. Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with imatinib mesylate against chronic myelogenous leukemia cell lines

    Directory of Open Access Journals (Sweden)

    Xin P

    2017-04-01

    Full Text Available Pengliang Xin, Chuntuan Li, Yan Zheng, Qunyi Peng, Huifang Xiao, Yuanling Huang, Xiongpeng Zhu Department of Haematology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Licheng, Quanzhou, Fujian Province, China Background: Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR pathway is a therapy target of cancer. We aimed to confirm the effect of dual PI3K/mTOR inhibitor NVP-BEZ235 on proliferation, apoptosis, and autophagy of chronic myelogenous leukemia (CML cells and sensitivity of tyrosine kinase inhibitor in vitro.Methods: Two human CML cell lines, K562 and KBM7R (T315I mutant strain, were used. The proliferation of CML cells was detected by MTS (Owen’s reagent assay. Cell cycle and apoptosis assay were examined by flow cytometric analysis. The phosphorylation levels and the expression levels were both evaluated by Western blot analysis. NVP-BEZ235 in combination with imatinib was also used to reveal the effect on proliferation and apoptosis.Results: NVP-BEZ235 significantly inhibited the proliferation in a time- and dose-dependent manner, and the half-maximal inhibitory concentration values of NVP-BEZ235 inhibiting the proliferation of K562 and KBM7R were 0.37±0.21 and 0.43±0.27 µmol/L, respectively, after 48 h. Cell apoptosis assay showed that NVP-BEZ235 significantly increased the late apoptotic cells. Cell cycle analysis indicated that the cells were mostly arrested in G1/G0 phase after treatment by NVP-BEZ235. In addition, results also found that, after treatment by NVP-BEZ235, phosphorylation levels of Akt kinase and S6K kinase significantly reduced, and the expression levels of cleaved caspase-3 significantly increased; meanwhile, the expression levels of caspase-3, B-cell lymphoma-2, cyclin D1, and cyclin D2 significantly decreased, and the ratio of LC3II/LC3I was significantly increased with increased LC3II expression level. Moreover, imatinib in combination with NVP-BEZ235

  8. Predication of Recrystallization and Mixed Grains in Q235 Steel Produced by CSP Hot Rolling%CSP热轧Q235钢再结晶与混晶的判定

    Institute of Scientific and Technical Information of China (English)

    张超; 吴润; 宋畅; 谭佳梅; 吴志方

    2011-01-01

    Q235 steel produced by CSP hot rolling was investigated to determine the occurrence condition of dynamic recrystallization and predicate the recrystallization and mixed grains. The results show that the kinetic model of dynanic recrystallization and dynamic recrystallization criterion for Q235 steel were obtained according to the true stress-true strain curves to predicate the recrystalli-zation and mixed grains, the results of model and criterion were different from the practice, because dynamic recrystallization of partial grains occured in the dynamic recovery sample's microstructure during the process of thermal simulation. It was necessary to consideration the factors of the storage and release of deformation work when judged accurately the occurrence of the mixed grain.%以CSP热轧QZ35钢为对象,研究了发生动态再结晶条件,对再结晶与混晶进行判定。结果表明:根据真应力一真应变曲线回归得出的Q235钢动态再结晶的动力学模型和再结晶判据来判断再结晶与混晶,与实际有一定的差别,这是因为热模拟时动态回复的组织中有部分晶粒发生了动态再结晶。要准确判断混晶的发生,还需考虑形变功的储存、释放等因素的干扰。

  9. 23.5 kW photovoltaic installation on the Customs House, Kreuzlingen, Switzerland; P+D Projekt 23.5 kWp PV Anlage Zollhof Kreuzlingen - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Boehni, T.; Stadelmann, G. [Boehni Energie und Umwelt GmbH, Frauenfeld (Switzerland)

    2005-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) describes the 23.5 kW photovoltaic installation on the Customs House in Kreuzlingen, Switzerland. The objective of the 'Zollhof' photovoltaic solar power plant is to provide the local population with a 'hands-on' solar cell experience, that, according to the authors, should lead to better understanding of renewable energy technology. The commissioning and initial operation of the installation is commented on, as are the above-average production figures of the plant. The power produced is sold by the local utility to its customers as electricity from renewable resources.

  10. 高压磨料水射流切割Q235钢试验研究%Experimental Research on Cutting Q235 Steel Using High-pressure Abrasive Water Jet

    Institute of Scientific and Technical Information of China (English)

    张滕飞; 邓松圣; 张世峡; 徐昆

    2016-01-01

    Q235 steel is widely used in the oil and gas industry. In order to investigate the performance of high⁃pressure abrasive water jet in the process of Q235 steel cutting, an experimental research was conducted by applying five⁃axis linkage post⁃mixed abrasive water jet cutting equipment to investigate the influence pumping pressure, incident angle, abrasive particle size, focusing tube diameter, transverse speed and standoff distance on cutting depth. Results show that cutting depth increases with the pump pressure linearly;cutting depth decreases with increasing transverse speed, and the decrease tends to be slow. There respectively exits optimal standoff distance, abrasive particle size and focusing tube diameter that make the cutting depth maximum. At a certain angle the cutting depth can be increased, and on the experimental condition, incident angle around 105° makes cutting depth maximal.%Q235钢在石油天然气行业应用广泛,为研究高压磨料水射流切割Q235钢的性能,应用五轴联动数控后混磨料水射流切割设备,分别研究泵压、入射角、磨料粒径、砂管直径、横移速度和靶距等参数对切割深度的影响。结果表明:切割深度随泵压增大而增大,且大致呈线性关系,随横移速度增大而减小,且减小趋于缓慢;其他条件一定时,分别存在最佳靶距、最佳磨料粒径和最佳砂管直径使得切割深度最大;一定的入射角倾斜可以增大切割深度,试验条件下入射角为105°左右时,切割深度达到最大。

  11. Population structure of Pseudomonas aeruginosa from five Mediterranean countries: evidence for frequent recombination and epidemic occurrence of CC235.

    Directory of Open Access Journals (Sweden)

    Makaoui Maatallah

    Full Text Available Several studies in recent years have provided evidence that Pseudomonas aeruginosa has a non-clonal population structure punctuated by highly successful epidemic clones or clonal complexes. The role of recombination in the diversification of P. aeruginosa clones has been suggested, but not yet demonstrated using multi-locus sequence typing (MLST. Isolates of P. aeruginosa from five Mediterranean countries (n = 141 were subjected to pulsed-field gel electrophoresis (PFGE, serotyping and PCR targeting the virulence genes exoS and exoU. The occurrence of multi-resistance (≥ 3 antipseudomonal drugs was analyzed with disk diffusion according to EUCAST. MLST was performed on a subset of strains (n = 110 most of them had a distinct PFGE variant. MLST data were analyzed with Bionumerics 6.0, using minimal spanning tree (MST as well as eBURST. Measurement of clonality was assessed by the standardized index of association (I(A (S. Evidence of recombination was estimated by ClonalFrame as well as SplitsTree4.0. The MST analysis connected 70 sequence types, among which ST235 was by far the most common. ST235 was very frequently associated with the O11 serotype, and frequently displayed multi-resistance and the virulence genotype exoS⁻/exoU⁺. ClonalFrame linked several groups previously identified by eBURST and MST, and provided insight to the evolutionary events occurring in the population; the recombination/mutation ratio was found to be 8.4. A Neighbor-Net analysis based on the concatenated sequences revealed a complex network, providing evidence of frequent recombination. The index of association when all the strains were considered indicated a freely recombining population. P. aeruginosa isolates from the Mediterranean countries display an epidemic population structure, particularly dominated by ST235-O11, which has earlier also been coupled to the spread of ß-lactamases in many countries.

  12. Monte-Carlo simulation for fragment mass and kinetic energy distributions from neutron induced fission of 235U

    CERN Document Server

    Montoya, M; Rojas, J

    2007-01-01

    The mass and kinetic energy distribution of nuclear fragments from thermal neutron induced fission of 235U have been studied using a Monte-Carlo simulation. Besides reproducing the pronounced broadening on the standard deviation of the final fragment kinetic energy distribution $\\sigma_{e}(m)$ around the mass number m = 109, our simulation also produces a second broadening around m = 125, that is in agreement with the experimental data obtained by Belhafaf et al. These results are consequence of the characteristics of the neutron emission, the variation in the primary fragment mean kinetic energy and the yield as a function of the mass.

  13. Calculation of the end-rolling strength in Q235 strip steel by the alloying electron structure parameters

    Institute of Scientific and Technical Information of China (English)

    LIU Zhilin; LIN Cheng; LIU Yan; GUO Yanchang

    2005-01-01

    Combined with the phase transformations in rolling, the phase configuration, the tensile strength, and the yield strength with different terminal rolling grain sizes in Q235 strip steel have been theoretically calculated using the covalent electron number (nA) of the strongest bond in phase cells and the interface electron density difference (Ap) in alloys. The calculated results agree well with the results of real production. Therefore, the calculation method of terminal rolling tensile and yield strength in the non-quenched-tempered steel containing pearlite is given by the alloying electron structure parameters.

  14. Radiation-chemical reaction of 2,3,5-triphenyl-tetrazolium chloride in liquid and solid state

    Science.gov (United States)

    Kovács, A.; Wojnárovits, L.; McLaughlin, W. L.; Eid, S. E. Ebrahim; Miller, A.

    1996-03-01

    In pulse radiolysis of 2,3,5-triphenyl-tetrazolium chloride (TTC) at around 360 nm fast formation of intermediate tetrazolium radical was observed under both oxidizing and reducing conditions. In the latter case bimolecular formation of formazan, absorbing at around 480 nm, was observed. This reaction is accompanied by combination to the diformazan dimer, absorbing over the spectral range 500-550 nm. A polyvinyl-alcohol-based TTC film was produced and tested for dosimetry purposes: it gave a measurable response in the 1-100 kGy dose range by evaluating the 50 μm thick TTC films at the absorption maximum of 493 nm.

  15. Radiation-chemical reaction of 2,3,5-triphenyl-tetrazolium chloride in liquid and solid state

    Energy Technology Data Exchange (ETDEWEB)

    Kovacs, A.; Wojnarovits, L. [Institute of Isotopes of the Hungarian Academy of Sciences, Budapest (Hungary); McLaughlin, W.L. [National Inst. of Standards and Technology, Gaithersburg, MD (United States); Ebrahim Eid, S.E. [National Centre for Radiation Research and Technology, Cairo (Egypt); Miller, A. [Risoe National Lab., Roskilde (Denmark)

    1996-03-01

    In pulse radiolysis of 2,3,5-triphenyl-tetrazolium chloride (TTC) at around 360 nm fast formation of intermediate tetrazolium radical was observed under both oxidizing and reducing conditions. In the latter case bimolecular formation of formazan, absorbing at around 480 nm, was observed. This reaction is accompanied by combination to the diformazan dimer, absorbing over the spectral range 500-550 nm. A polyvinyl-alcohol-based TTC film was produced and tested for dosimetry purposes: it gave a measurable response in the 1-100 kGy dose range by evaluating the 50 {mu}m thick TTC films at the absorption maximum of 493 nm. (author).

  16. Study on Surface Layer of Q235 Steel Made by Micro-nitrocarburizing%Q235钢在溶液中微弧氮碳共渗改性层的探究

    Institute of Scientific and Technical Information of China (English)

    蒋永锋; 耿亭; 包晔峰; 朱燕华

    2012-01-01

    The Q235 steel surface layer was made by micro-nitrocarburizing in the aqueous solution. The metallographic structure, morphology, phase and microhardness of the coating were evaluated by optical microscopy, SEM, XRD and microhardness meters respectively, and then the technological conditions and courses were discussed. The results show that the hardness of the surface layer is much more higher than that of the matrix.%在甲酰胺电解溶液体系中,对Q235钢进行微弧氮碳共渗处理,观察被处理工件的改性层显微组织,借助SEM及XRD分别观测改性层形貌,检测改性层的相组成,最后利用显微硬度计测试改性层的硬度.结果表明,经溶液微弧氮碳共渗处理后的试样改性层硬度约为基体硬度的3倍.

  17. Effect of iron content on permeability and power loss characteristics of Li0.35Cd0.3Fe2.35O4 and Li0.35Zn0.3Fe2.35O4

    Indian Academy of Sciences (India)

    Vivek Verma; Prachi Sharma; Adarsh Singh

    2014-06-01

    Substituted lithium ferrites having the chemical formula, Li0.35Cd0.3Fe2.35O4 and Li0.35Zn0.3Fe2.35O4, with different iron (metal) contents (2, 4, 6, 8 and 10) in wt% have been prepared by solid-state technique. Complex permeability and power loss of all samples have been measured by network analyser in the frequency range of 50–5000 kHz. Magnetic properties like saturation magnetization, coercivity, retentivity have been measured by vibrating sample magnetometer (VSM). The permeability of cadmium doped lithium ferrites exhibited higher values than zinc doped lithium ferrites. The power loss of cadmium doped lithium ferrites is lesser as compared to zinc doped lithium ferrites in the frequency range of 50–5000 kHz and at flux density of 10 mT. The behaviour of power loss with flux density has been found near about same for both series. Magnetic and power loss behaviour of the samples suggest that a small amount of Fe content can improve the properties of ferrite samples for microwave devices.

  18. Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release.

    Science.gov (United States)

    Pivavarchyk, Marharyta; Smith, Andrew M; Zhang, Zhenfa; Zhou, Dejun; Wang, Xu; Toyooka, Naoki; Tsuneki, Hiroshi; Sasaoka, Toshiyasu; McIntosh, J Michael; Crooks, Peter A; Dwoskin, Linda P

    2011-05-11

    Although several therapeutic agents are available to aid in tobacco smoking cessation, relapse rates continue to be high, warranting the development of alternative pharmacotherapies. Nicotine-evoked dopamine release from its presynaptic terminals in the central nervous system leads to reward which maintains continued tobacco use. The ability of indolizidine (-)-235B' and a sub-library of structurally related analogs to inhibit nicotine-evoked [(3)H]dopamine release from rat striatal slices was determined in the current study. Indolizidine (-)-235B' inhibited nicotine-evoked [(3)H]dopamine release in a concentration-dependent manner (IC(50)=42 nM, I(max)=55%). Compound (-)-237D, the double bond-reduced analog, afforded the greatest inhibitory potency (IC(50)=0.18 nM, I(max)=76%), and was 233-fold more potent than indolizidine (-)-235B'. The des-8-methyl aza-analog of indolizidine (-)-235B', ZZ-272, also inhibited nicotine-evoked [(3)H]dopamine release (IC(50)=413 nM, I(max)=59%). Concomitant exposure to maximally effective concentrations of indolizidine (-)-235B', ZZ-272 or (-)-237D with a maximally effective concentration of α-conotoxin MII, a selective antagonist for α6β2-containing nicotinic receptors, resulted in inhibition of nicotine-evoked [(3)H]dopamine release no greater than that produced by each compound alone. The latter results suggest that indolizidine (-)-235B', (-)-237D, ZZ-272 and α-conotoxin MII inhibit the same α-conotoxin MII-sensitive nicotinic receptor subtypes. Thus, indolizidine (-)-235B' and its analogs act as antagonists of α6β2-nicotinic receptors and constitute a novel structural scaffold for the discovery of pharmacotherapies for smoking cessation.

  19. Evaluation of molecularly imprinted polymers using 2',3',5'-tri-O-acyluridines as templates for pyrimidine nucleoside recognition.

    Science.gov (United States)

    Krstulja, Aleksandra; Lettieri, Stefania; Hall, Andrew J; Delépée, Raphael; Favetta, Patrick; Agrofoglio, Luigi A

    2014-10-01

    In this paper, we describe the synthesis and evaluation of molecularly imprinted polymers (MIPs), prepared using 2',3',5'-tri-O-acyluridines as 'dummy' templates, for the selective recognition of uridine nucleosides. The MIPs were synthesised using a non-covalent approach with 2,6-bis-acrylamidopyridine (BAAPy) acting as the binding monomer and ethylene glycol dimethacrylate (EGDMA) as the cross-linking agent. The MIPs were evaluated in terms of capacity, selectivity and specificity by analytical and frontal liquid chromatography measurements. The results obtained in organic mobile phases suggest that the nucleosides are specifically bound to the polymer by the complementary hydrogen bonding motifs of the binding monomer and the nucleoside bases. The MIPs exhibited relatively high imprinting factors for 2',3',5'-tri-O-acyluridines, while they did not show any binding capacity for other nucleosides lacking the imide moiety on their base. Moreover, the presence of ester-COO groups in the EGDMA cross-linker may lead to the formation of additional hydrogen bonds with the 2',3' and/or 5'-OH of sugar part, allowing enhancement of the recognition of the uridine nucleosides. In aqueous media, results show that the binding is driven by hydrophobic interactions.

  20. 235U–231Pa age dating of uranium materials for nuclear forensic investigations

    Energy Technology Data Exchange (ETDEWEB)

    Eppich, Gary R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Williams, Ross W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gaffney, Amy M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Schorzman, Kerri C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-04-03

    Here, age dating of nuclear material can provide insight into source and suspected use in nuclear forensic investigations. We report here a method for the determination of the date of most recent chemical purification for uranium materials using the 235U-231Pa chronometer. Protactinium is separated from uranium and neptunium matrices using anion exchange resin, followed by sorption of Pa to an SiO2 medium. The concentration of 231Pa is measured by isotope dilution mass spectrometry using 233Pa spikes prepared from an aliquot of 237Np and calibrated in-house using the rock standard Table Mountain Latite and the uranium isotopic standard U100. Combined uncertainties of age dates using this method are 1.5 to 3.5 %, an improvement over alpha spectrometry measurement methods. Model ages of five uranium standard reference materials are presented; all standards have concordant 235U-231Pa and 234U-230Th model ages.

  1. A generalized method for characterization of 235U and 239Pu content using short-lived fission product gamma spectroscopy

    Science.gov (United States)

    Knowles, Justin; Skutnik, Steven; Glasgow, David; Kapsimalis, Roger

    2016-10-01

    Rapid nondestructive assay methods for trace fissile material analysis are needed in both nuclear forensics and safeguards communities. To address these needs, research at the Oak Ridge National Laboratory High Flux Isotope Reactor Neutron Activation Analysis facility has developed a generalized nondestructive assay method to characterize materials containing fissile isotopes. This method relies on gamma-ray emissions from short-lived fission products and makes use of differences in fission product yields to identify fissile compositions of trace material samples. Although prior work has explored the use of short-lived fission product gamma-ray measurements, the proposed method is the first to provide a complete characterization of isotopic identification, mass ratios, and absolute mass determination. Successful single fissile isotope mass recoveries of less than 6% recovery bias have been conducted on standards of 235U and 239Pu as low as 12 ng in less than 10 minutes. Additionally, mixtures of fissile isotope standards containing 235U and 239Pu have been characterized as low as 198 ng of fissile mass with less than 7% recovery bias. The generalizability of this method is illustrated by evaluating different fissile isotopes, mixtures of fissile isotopes, and two different irradiation positions in the reactor. It is anticipated that this method will be expanded to characterize additional fissile nuclides, utilize various irradiation facilities, and account for increasingly complex sample matrices.

  2. Volume-of-interest cone-beam CT using a 2.35 MV beam generated with a carbon target.

    Science.gov (United States)

    Robar, James L; Parsons, David; Berman, Avery; Macdonald, Alex

    2012-07-01

    This is a proof-of-concept study addressing volume of interest (VOI) cone beam CT (CBCT) imaging using an x-ray beam produced by 2.35 MeV electrons incident on a carbon linear accelerator target. Methodology is presented relevant to VOI CBCT image acquisition and reconstruction. Sample image data are given to demonstrate and compare two approaches to minimizing artifacts arising from reconstruction with truncated projections. Dosimetric measurements quantify the potential dose reduction of VOI acquisition relative to full-field CBCT. The dependence of contrast-to-noise ratio (CNR) on VOI dimension is investigated. A paradigm is presented linking the treatment planning process with the imaging technique, allowing definition of an imaging VOI to be tailored to the geometry of the patient. Missing data in truncated projection images are completed using a priori information in the form of digitally reconstructed radiographs (DRRs) generated from the planning CT set. This method is compared to a simpler technique of extrapolating truncated projection data prior to reconstruction. The utility of these approaches is shown through imaging of a geometric phantom and the head-and-neck section of a lamb. The total scatter factor of the 2.35 MV∕carbon beam on field size is measured and compared to a standard therapeutic beam to estimate the comparative dose reduction inside the VOI. Thermoluminescent dosimeters and Gafchromic film measurements are used to compare the imaging dose distributions for the 2.35 MV∕carbon beam between VOI and full-field techniques. The dependence of CNR on VOI dimension is measured for VOIs ranging from 4 to 15 cm diameter. Without compensating for missing data outside of truncated projections prior to reconstruction, pronounced boundary artifacts are present, in three dimensions, within 2-3 cm of the edges of the VOI. These artifacts, as well as cupping inside the VOI, can be reduced substantially using either the DRR filling or extrapolation

  3. Relationship Between pH and Electrochemical Corrosion Behavior of Thermal-Sprayed Ni-Al-Coated Q235 Steel in Simulated Soil Solutions

    Science.gov (United States)

    Wei, Wei; Wu, Xin-qiang; Ke, Wei; Xu, Song; Feng, Bing; Hu, Bo-tao

    2017-09-01

    Electrochemical corrosion behavior of a thermal-sprayed Ni-Al-coated Q235 steel was investigated in the simulated soil solutions at different pH values using measurements of potentiodynamic polarization curves and electrochemical impedance spectroscopy as well as surface analyses including x-ray diffraction analysis, scanning electron microscope equipped with an energy-dispersive x-ray spectroscopy and x-ray photoelectron spectroscopy. The results showed that the corrosion resistance of the Ni-Al-coated Q235 steel was dependent on the pH of the test solution. From pH = 3.53 to pH = 4.79, the corrosion resistance of the coated steel increased rapidly. In the pH range from 4.79 to 12.26, the corrosion resistance exhibited no significant change. At pH 13.25, the corrosion resistance of the sample was found to decrease. The calculated corrosion rate of Ni-Al-coated Q235 steel was lower than that of the uncoated Q235 steel and galvanized steel in all the test solutions. Over a wide range of pH values, the Ni-Al-coated Q235 steel exhibited extremely good corrosion resistance. The experimental data together with the potential-pH diagrams provided a basis for a detailed discussion of the related corrosion mechanisms of the coated steel.

  4. 热像法和能量法快速评估Q235钢的疲劳性能%Fast Evaluation of Fatigue Behavior of Q235 Steel by Infrared Thermography and Energy Approach

    Institute of Scientific and Technical Information of China (English)

    樊俊铃; 郭杏林; 吴承伟; 邓德伟

    2012-01-01

    借助热像法和能量法快速确定了单轴循环应力作用下Q235钢的疲劳性能参数,与传统实验结果相比,吻合较好.基于极限能理论假设,建立了Miner线性累积损伤理论的能量模型以预测构件的残余寿命.研究结果表明:热像法和能量法可以在较短的实验周期内快速地确定材料的疲劳极限和S-N曲线等疲劳性能参数;Miner理论的能量模型具有明确的物理意义,能准确预测循环载荷作用下构件的残余寿命.%The infrared thermography was used to rapidly determine the fatigue parameters of Q235 steel undergoing uniaxial cyclic stress, and a good agreement was achieved between the predicted results and the results from the traditional fatigue testing methods. Based on the assumption of the limiting energy theory, the energy approach based on Miner's law was advanced to predict the residual fatigue life of samples. The results show that the infrared thermography and the energy approach can be used to rapidly determine the fatigue limit and the S-N curve in a short test period; and that the residual fatigue life can be accurately predicted by the energy approach based on Miner's law with clear physical meaning.

  5. 235株血培养病原菌分布及药物敏感性分析%Clinical distribution and drug susceptibility of 235 blood culture pathogens

    Institute of Scientific and Technical Information of China (English)

    贾珉

    2012-01-01

    目的 了解血培养分离的常见病原菌分布及药物敏感性.方法 采用BacT/Alert3D全自动血培养仪、VITEK-2 Compact细菌鉴定仪进行血培养、病原菌鉴定及药敏试验.结果 从3180份血培养中共分离出病原菌235株,阳性率为7.4%;其中革兰阳性菌占21.7%,革兰阴性菌占76.6%,真菌占1.7%;MRSA检出率为18.8%.结论 血培养病原菌药物敏感性差异较大,临床应根据血培养检测结果合理用药.%OBJECTIVE To understand the distributio以n and drug susceptibility of common pathogenic bacteria cultured from blood. METHODS The blood culture, strain identification and the drug susceptibility testing were performed by BacT/Aler3D automated blood culture system in combination with VTTEK-2 compact. RESULTS The positive rate of blood culture was 7. 4% (235/3180) ; gram-positive bacteria, gram-negative bacteria and fungi accounted for 21.7%, 76. 6% and 1. 7%, respectively; the isolation rate of MRSA was 18. 8%. CONCLUSION There is a significant difference in the drug susceptibility among pathogenic bacteria cultured from blood, the clinician should use the antibiotics reasonably according to the result of blood culture.

  6. Contribution to the study of the thermal fission process for uranium 235 (1964); Contribution a l'etude du processus de la fission thermique de l'uranium 235 (1964)

    Energy Technology Data Exchange (ETDEWEB)

    Chahrtache, M. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-12-15

    This report deals with the study of the distribution of the masses of the fragments produced by the disintegration of the U-236 nucleus, formed when a U-235 nucleus captures a thermal neutron. The experimental method chosen consists in the simultaneous measurement using p-n silicon junction detectors of the energies of the two fragments emitted in coincidence. This measurement is first made by a conditioned analysis of the energy of one of the fragments and then by a two dimensional analysis of the energies of the two fragments. Systematic results, are obtained concerning the distribution of the masses for different values of the total kinetic energy. The five structures appearing both for the mass distributions and for the energies of the fragments are studied and discussed. Generally speaking, our results are in agreement with those obtained by the time-of-flight method. (author) [French] Le present rapport a pour objet t'etude de la distribution des masses des fragments emis lors de la fission du noyau U-236, forme par capture d'un neutron thermique par un noyau d'U-235. La methode experimentale choisie consiste en la mesure simultanee - a l'aide de detecteurs a jonction p-n au silicium des energies des deux fragments emis en coincidence. Cette mesure est d'abord effectuee par analyse conditionnee de l'energie de l'un des fragments puis par analyse bidimensionnelle des energies des deux fragments. Des resultats systematiques sont obtenus sur les distributions des masses pour differentes valeurs de l'energie cinetique totale. Les 'structures fines' apparaissant tant sur les distributions des masses que sur celles des energies des fragments sont egalement etudiees et discutees. D'une facon generale, nos resultats sont en accord avec ceux obtenus par la methode du temps de vol. (auteur)

  7. Causes Analysis on Fracture of a Q235B Steel Circulating Water Main Pipe%Q235B钢循环水母管断裂原因分析

    Institute of Scientific and Technical Information of China (English)

    刘倩倩; 句光宇; 王志武

    2016-01-01

    某发电公司1000 MW燃煤发电机组在运行中,Q235B 钢循环水母管发生断裂。通过宏观检验、化学成分分析、力学性能测试、金相检验、扫描电镜及能谱分析等方法,对循环水母管的断裂原因进行了分析。结果表明:循环水母管焊缝部位存在未焊透现象及焊渣、焊瘤等夹杂物,焊接质量低、显微组织异常导致焊缝处承载能力差;在腐蚀环境存在的情况下,裂纹在焊渣处形成并快速扩展,导致循环水母管断裂失效。%A circulating water main pipe of Q235B steel in a 1 000 MW coal-fired power generation of a power plant fractured during operation.The fracture causes of the circulation water main pipe were analyzed by means of macroscopic inspection,chemical compositions analysis,mechanical properties testing,metallographic inspection, scanning electron microscope analysis,energy spectrum analysis and so on.The results show that:incomplete penetration phenomenon and inclusions,such as welding slag,welding beading and so on,existed in the welding seam of the circulating water pipe;low welding quality and abnormal microstructure caused poor bearing capacity of the welding seam.In the corrosion environment,cracks generated in the area of welding slag and expanded rapidly, resulting in the fracture failure of the circulating water main pipe.

  8. 206Pb-230Th-234U-238U and 207Pb-235U geochronology of Quaternary opal, Yucca Mountain, Nevada

    Science.gov (United States)

    Neymark, Leonid A.; Amelin, Yuri V.; Paces, James B.

    2000-01-01

    U–Th–Pb isotopic systems have been studied in submillimeter-thick outermost layers of Quaternary opal occurring in calcite–silica fracture and cavity coatings within Tertiary tuffs at Yucca Mountain, Nevada, USA. These coatings preserve a record of paleohydrologic conditions at this site, which is being evaluated as a potential high-level nuclear waste repository. The opal precipitated from groundwater is variably enriched in 234U (measured 234U/238U activity ratio 1.124–6.179) and has high U (30–313 ppm), low Th (0.008–3.7 ppm), and low common Pb concentrations (measured 206Pb/204Pb up to 11,370). It has been demonstrated that the laboratory acid treatment used in this study to clean sample surfaces and to remove adherent calcite, did not disturb U–Th–Pb isotopic systems in opal. The opal ages calculated from 206Pb∗/238U and 207Pb∗/235U ratios display strong reverse discordance because of excess radiogenic 206Pb∗ derived from the elevated initial 234U. The data are best interpreted using projections of a new four-dimensional concordia diagram defined by 206Pb∗/238U, 207Pb∗/235U, 234U/238Uactivity, and 230Th/238Uactivity. Ages and initial 234U/238U activity ratios have been calculated using different projections of this diagram and tested for concordance. The data are discordant, that is observed 207Pb∗/235U ages of 170 ± 32 (2σ) to 1772 ± 40 ka are systematically older than 230Th/U ages of 34.1 ± 0.6 to 452 ± 32 ka. The age discordance is not a result of migration of uranium and its decay products under the open system conditions, but a consequence of noninstantaneous growth of opal. Combined U–Pb and 230Th/U ages support the model of slow mineral deposition at the rates of millimeters per million years resulting in layering on a scale too fine for mechanical sampling. In this case, U–Pb ages provide more accurate estimates of the average age for mixed multiage samples than 230Th/U ages, because ages based on shorter

  9. Fission Product Yields of 233U, 235U, 238U and 239Pu in Fields of Thermal Neutrons, Fission Neutrons and 14.7-MeV Neutrons

    Science.gov (United States)

    Laurec, J.; Adam, A.; de Bruyne, T.; Bauge, E.; Granier, T.; Aupiais, J.; Bersillon, O.; Le Petit, G.; Authier, N.; Casoli, P.

    2010-12-01

    The yields of more than fifteen fission products have been carefully measured using radiochemical techniques, for 235U(n,f), 239Pu(n,f) in a thermal spectrum, for 233U(n,f), 235U(n,f), and 239Pu(n,f) reactions in a fission neutron spectrum, and for 233U(n,f), 235U(n,f), 238U(n,f), and 239Pu(n,f) for 14.7 MeV monoenergetic neutrons. Irradiations were performed at the EL3 reactor, at the Caliban and Prospero critical assemblies, and at the Lancelot electrostatic accelerator in CEA-Valduc. Fissions were counted in thin deposits using fission ionization chambers. The number of fission products of each species were measured by gamma spectrometry of co-located thick deposits.

  10. A Neutronic Analysis of TRU Recycling in PWRs Loaded with MOX-UE Fuel (MOX with U-235 Enriched U Support)

    Energy Technology Data Exchange (ETDEWEB)

    G. Youinou; S. Bays

    2009-05-01

    This report presents the results of a study dealing with the homogeneous recycling of either Pu or Pu+Np or Pu+Np+Am or Pu+Np+Am+Cm in PWRs using MOX-UE fuel, i.e. standard MOX fuel with a U235 enriched uranium support instead of the standard tail uranium (0.25%) for standard MOX fuel. This approach allows to multirecycle Pu or TRU (Pu+MA) as long as U235 is available, by keeping the Pu or TRU content in the fuel constant and at a value ensuring a negative moderator void coefficient (i.e. the loss of the coolant brings imperatively the reactor to a subcritical state). Once this value is determined, the U235 enrichment of the MOX-UE fuel is adjusted in order to reach the target burnup (51 GWd/t in this study).

  11. Contributions in the Preparation and Processing of Composite Material Type Silumin 3 - Reinforced Matrix with S235JR Steel Mesh

    Directory of Open Access Journals (Sweden)

    Remus Belu-Nica

    2015-07-01

    Full Text Available In the paper are presented concrete data on developing technological batches of metal composite material (MCM type Silumin 3-reinforced matrix with steel mesh S235JR, with the indicating of the parameter and of the distinct stages of work. The samples from prepared batches were cut along and across by water jet abrasive process and were subjected to a destructive testing program and microstructural examination, obtaining results in concordance with the desired quality. The abrasive material used for cut was GMA granite with the average mesh of 80, the particle size ranging between 150-300 µm, density 2300 kg/m3 and melting point 1240°C.

  12. Collinear cluster tripartition as sequential binary fission in the $^{235}$U(n$_{\\rm th}$,f) reaction

    CERN Document Server

    Tashkhodjaev, R B; Scheid, W

    2011-01-01

    The mechanism leading to the formation of the observed products of the collinear cluster tripartition is carried out within the framework of the model based on the dinuclear system concept. The yield of fission products is calculated using the statistical model based on the driving potentials for the fissionable system. The minima of potential energy of the decaying system correspond to the charge numbers of the products which are produced with large probabilities in the sequential fission (partial case of the collinear cluster tripartition) of the compound nucleus. The realization of this mechanism supposes the asymmetric fission channel as the first stage of sequential mechanism. It is shown that only the use of the driving potential calculated by the binding energies with the shell correction allows us to explain the yield of the true ternary fission products. The theoretical model is applied to research collinear cluster tripartition in the reaction $^{235}$U(n$_{\\rm th}$,f). Calculations showed that in t...

  13. Study of Photon Strength Functions of Actinides: the case of U-235, Np-238 and Pu-241

    CERN Document Server

    Guerrero, C; Cano-Ott, D; Martinez, T; Mendoza, E; Villamarin, D; Colonna, N; Meaze, M H; Marrone, S; Tagliente, G; Terlizzi, R; Belloni, F; Abbondanno, U; Fujii, K; Milazzo, P M; Moreau, C; Aerts, G; Berthoumieux, E; Dridi, W; Gunsing, F; Pancin, J; Perrot, L; Plukis, A; Alvarez, H; Duran, I; Paradela, C; Andriamonje, S; Calviani, M; Chiaveri, E; Gonzalez-Romero, E; Kadi, Y; Vicente, M C; Vlachoudis, V; Andrzejewski, J; Marganiec, J; Assimakopoulos, P; Karadimos, D; Karamanis, D; Papachristodoulou, C; Patronis, N; Audouin, L; David, S; Ferrant, L; Isaev, S; Stephan, C; Tassan-Got, L; Badurek, G; Jericha, E; Leeb, H; Oberhummer, H; Pigni, M T; Baumann, P; Kerveno, M; Lukic, S; Rudolf, G; Becvar, F; Krticka, M; Calvino, F; Capote, R; Carrillo De Albornoz, A; Marques, L; Salgado, J; Tavora, L; Vaz, P; Cennini, P; Dahlfors, M; Ferrari, A; Gramegna, F; Herrera-Martinez, A; Mastinu, P; Praena, J; Sarchiapone, L; Wendler, H; Chepel, V; Ferreira-Marques, R; Goncalves, I; Lindote, A; Lopes, I; Neves, F; Cortes, G; Poch, A; Pretel, C; Couture, A; Cox, J; O'brien, S; Wiescher, M; Dillman, I; Kappeler, F; Mosconi, M; Plag, R; Voss, F; Walter, S; Wisshak, K; Dolfini, R; Rubbia, C; Domingo-Pardo, C; Tain, J L; Eleftheriadis, C; Savvidis, I; Frais-Koelbl, H; Griesmayer, E; Furman, W; Konovalov, V; Goverdovski, A; Ketlerov, V; Haas, B; Haight, R; Reifarth, R; Heil, M; Igashira, M; Koehler, P; Kossionides, E; Lampoudis, C; Lozano, M; Quesada, J; Massimi, C; Vannini, G; Mengoni, A; Oshima, M; Papadopoulos, C; Vlastou, R; Pavlik, A; Pavlopoulos, P; Plompen, A; Rullhusen, P; Rauscher, T; Rosetti, M; Ventura, A

    2011-01-01

    The decay from excited levels in medium and heavy nuclei can be described in a statistical approach by means of Photon Strength Functions and Level Density distributions combined with the theory of the compound. The study of electromagnetic cascades following neutron capture by means of high efficiency detectors has been shown to be well suited for probing the properties of the Photon Strength Function of heavy (high level density) and/or radioactive (high background) nuclei. In this work we have investigated for the first time the validity of the recommended PSF for actinides, in particular 235U, 238Np and 241Pu. Our study includes the search for resonance structures in the PSF below Sn and draws conclusions regarding their existence and their characteristics in terms of energy, width and electromagnetic nature.

  14. Joint association of physical activity in leisure and total sitting time with metabolic syndrome amongst 15,235 Danish adults

    DEFF Research Database (Denmark)

    Petersen, Christina Bjørk; Nielsen, Asser Jon; Bauman, Adrian;

    2014-01-01

    and total daily sitting time were assessed by self-report in 15,235 men and women in the Danish Health Examination Survey 2007-2008. Associations between leisure time physical activity, total sitting time and metabolic syndrome were investigated in logistic regression analysis. RESULTS: Adjusted odds ratios......BACKGROUND: Recent studies suggest that physical inactivity as well as sitting time are associated with metabolic syndrome. Our aim was to examine joint associations of leisure time physical activity and total daily sitting time with metabolic syndrome. METHODS: Leisure time physical activity...... (OR) for metabolic syndrome were 2.14 (95% CI: 1.88-2.43) amongst participants who were inactive in leisure time compared to the most active, and 1.42 (95% CI: 1.26-1.61) amongst those who sat for ≥10h/day compared to

  15. Simultaneous {sup 233}U and{sup 235}U characterization through the assay of delayed neutron temporal behavior

    Energy Technology Data Exchange (ETDEWEB)

    Sellers, M. T.; Corcoran, E. C.; Kelly, D. G. [Dept. of Chemistry and Chemical Engineering, Royal Military College of Canada, Stn. Forces, P.O. Box 17000, Kingston, ON K7K 7B4 (Canada)

    2012-07-01

    Aqueous solutions containing dissolved uranium-233 and uranium-235 were irradiated for 60's in the SLOWPOKE-2 reactor at the Royal Military College of Canada. The temporal behavior of the delayed neutrons produced was recorded by the Facility's Delayed Neutron Counting (DNC) system. The percentage of uranium-233 as a function of total fissile mass present in each sample ranged from 0 to 100% and was predicted by the DNC system with average absolute errors of {+-} 4%. Future work will upgrade the system electronics and software to reduce both uncertainties in timings and electrical noise. Mixture analysis will also be expanded to include plutonium-239 and fissile materials contained in non-aqueous matrices. (authors)

  16. Simultaneous measurement of fission fragments and prompt neutrons for thermal neutron-induced fission of U-235

    Energy Technology Data Exchange (ETDEWEB)

    Nishio, Katsuhisa; Yamamoto, Hideki; Kimura, Itsuro; Nakagome, Yoshihiro [Kyoto Univ. (Japan)

    1997-03-01

    Simultaneous measurement of fission fragments and prompt neutrons following the thermal neutron induced fission of U-235 has been performed in order to obtain the neutron multiplicity (v) and its emission energy ({eta}) against the specified mass (m{sup *}) and the total kinetic energy (TKE). The obtained value of -dv/dTKE(m{sup *}) showed a saw-tooth distribution. The average neutron energy <{eta}>(m{sup *}) had a distribution with a reflection symmetry around the half mass division. The measurement also gave the level density parameters of the specified fragment, a(m{sup *}), and this parameters showed a saw-tooth trend too. The analysis by a phenomenological description of this parameters including the shell and collective effects suggested the existence of a collective motion of the fission fragments. (author)

  17. Molecular analysis of a male breast cancer patient with prolonged stable disease under mTOR/PI3K inhibitors BEZ235/everolimus

    Science.gov (United States)

    Brannon, A. Rose; Frizziero, Melissa; Chen, David; Hummel, Jennifer; Gallo, Jorge; Riester, Markus; Patel, Parul; Cheung, Wing; Morrissey, Michael; Carbone, Carmine; Cottini, Silvia; Tortora, Giampaolo; Melisi, Davide

    2016-01-01

    The mTORC1 inhibitor everolimus (Afinitor/RAD001) has been approved for multiple cancer indications, including ER+/HER2− metastatic breast cancer. However, the combination of everolimus with the dual PI3K/mTOR inhibitor BEZ235 was shown to be more efficacious than either everolimus or BEZ235 alone in preclinical models. Herein, we describe a male breast cancer (MBC) patient who was diagnosed with hormone receptor-positive (HR+)/HER2− stage IIIA invasive ductal carcinoma and sequentially treated with chemoradiotherapy and hormonal therapy. Upon the development of metastases, the patient began a 200 mg twice-daily BEZ235 and 2.5 mg weekly everolimus combination regimen. The patient sustained a prolonged stable disease of 18 mo while undergoing the therapy, before his tumor progressed again. Therefore, we sought to both better understand MBC and investigate the underlying molecular mechanisms of the patient's sensitivity and subsequent resistance to the BEZ235/everolimus combination therapy. Genomic and immunohistochemical analyses were performed on samples collected from the initial invasive ductal carcinoma pretreatment and a metastasis postprogression on the BEZ235/everolimus combination treatment. Both tumors were relatively quiet genomically with no overlap to recurrent MBC alterations in the literature. Markers of PI3K/mTOR pathway hyperactivation were not identified in the pretreatment sample, which complements previous reports of HR+ female breast cancers being responsive to mTOR inhibition without this activation. The postprogression sample, however, demonstrated greater than fivefold increased estrogen receptor and pathogenesis-related protein expression, which could have constrained the PI3K/mTOR pathway inhibition by BEZ235/everolimus. Overall, these analyses have augmented the limited episteme on MBC genetics and treatment. PMID:27148582

  18. Molecular analysis of a male breast cancer patient with prolonged stable disease under mTOR/PI3K inhibitors BEZ235/everolimus.

    Science.gov (United States)

    Brannon, A Rose; Frizziero, Melissa; Chen, David; Hummel, Jennifer; Gallo, Jorge; Riester, Markus; Patel, Parul; Cheung, Wing; Morrissey, Michael; Carbone, Carmine; Cottini, Silvia; Tortora, Giampaolo; Melisi, Davide

    2016-03-01

    The mTORC1 inhibitor everolimus (Afinitor/RAD001) has been approved for multiple cancer indications, including ER(+)/HER2(-) metastatic breast cancer. However, the combination of everolimus with the dual PI3K/mTOR inhibitor BEZ235 was shown to be more efficacious than either everolimus or BEZ235 alone in preclinical models. Herein, we describe a male breast cancer (MBC) patient who was diagnosed with hormone receptor-positive (HR(+))/HER2(-) stage IIIA invasive ductal carcinoma and sequentially treated with chemoradiotherapy and hormonal therapy. Upon the development of metastases, the patient began a 200 mg twice-daily BEZ235 and 2.5 mg weekly everolimus combination regimen. The patient sustained a prolonged stable disease of 18 mo while undergoing the therapy, before his tumor progressed again. Therefore, we sought to both better understand MBC and investigate the underlying molecular mechanisms of the patient's sensitivity and subsequent resistance to the BEZ235/everolimus combination therapy. Genomic and immunohistochemical analyses were performed on samples collected from the initial invasive ductal carcinoma pretreatment and a metastasis postprogression on the BEZ235/everolimus combination treatment. Both tumors were relatively quiet genomically with no overlap to recurrent MBC alterations in the literature. Markers of PI3K/mTOR pathway hyperactivation were not identified in the pretreatment sample, which complements previous reports of HR(+) female breast cancers being responsive to mTOR inhibition without this activation. The postprogression sample, however, demonstrated greater than fivefold increased estrogen receptor and pathogenesis-related protein expression, which could have constrained the PI3K/mTOR pathway inhibition by BEZ235/everolimus. Overall, these analyses have augmented the limited episteme on MBC genetics and treatment.

  19. Al2O3-TiC/Q235真空扩散钎焊界面组织及抗剪强度%Microstructure and shear strength of diffusion brazed Al2O3-TiC/Q235 joint

    Institute of Scientific and Technical Information of China (English)

    王娟; 李亚江; S. A. GERASIMOV

    2008-01-01

    为了获得Al2O3-Tic陶瓷基复合材料与Q235钢的接头,采用Ti/cu/Ti复合中间层对Al2O3-Tic复合材料与Q235低碳钢进行了真空扩散钎焊.通过扫描电镜、能谱分析和电子探针、抗剪试验等测试方法对Al2O3-TiC/Q235扩散钎焊界面的组织、成分及结合强度进行分析.结果表明,控制加热温度为1110℃,可获得界面抗剪强度122 MPa的Al2O3-TiC/Q235扩散钎焊接头,Ti/cu/Ti复合中间层与Al2O3-TiC和Q235润湿性较好,并发生一定程度的扩散反应,在Al2O3-TiC与Q235之间形成厚度约80μm的界面过渡区,过渡区内形成的组织结构主要是Ti3AlC2,Fe2Ti,Cu和TiC.

  20. The Significance of Minimally Invasive Core Needle Biopsy and Immunohistochemistry Analysis in 235 Cases with Breast Lesions

    Institute of Scientific and Technical Information of China (English)

    Yun Niu; Tieju Liu; Xuchen Cao; Xiumin Ding; Li Wei; Yuxia Gao; Jun Liu

    2009-01-01

    OBJECTIVE To evaluate core needle biopsy (CNB) as a mini-mally invasive method to examine breast lesions and discuss the clinical significance of subsequent immunohistochemistry (IHC)analysis.METHODS The clinical data and pathological results of 235 pa-tients with breast lesions, who Received CNB before surgery, were analyzed and compared. Based on the results of CNB done before surgery, 87 out of 204 patients diagnosed as invasive carcinoma were subjected to immunodetection for p53, c-erbB-2, ER and PR.The morphological change of cancer tissues in response to chemo-therapy was also evaluated.RESULTS In total of 235 cases receiving CNB examination, 204 were diagnosed as invasive carcinoma, reaching a 100% consistent rate with the surgical diagnosis. Sixty percent of the cases diag-nosed as non-invasive carcinoma by CNB was identified to have the presence of invading elements in surgical specimens, and simi-larly, 50% of the cases diagnosed as atypical ductal hyperplasia by CNB was confirmed to be carcinoma by the subsequent result of excision biopsy. There was no significant difference between the CNB biopsy and regular surgical samples in positive rate of im-munohistochemistry analysis (p53, c-erbB-2, ER and PR; P > 0.05).However, there was significant difference in the expression rate of p53 and c-erbB-2 between the cases with and without morphologi-cal change in response to chemotherapy (P < 0.05). In most cases with p53 and c-erbB-2 positive, there was no obvious morphologi-cal change after chemotherapy. CONCLUSION CNB is a cost-effective diagnostic method with minimal invasion for breast lesions, although it still has some limi-tations. Immunodetection on CNB tissue is expected to have great significance in clinical applications.

  1. Reactive transport of uranium in a groundwater bioreduction study: Insights from high-temporal resolution 238U/235U data

    Science.gov (United States)

    Shiel, A. E.; Johnson, T. M.; Lundstrom, C. C.; Laubach, P. G.; Long, P. E.; Williams, K. H.

    2016-08-01

    We conducted a detailed investigation of U isotopes in conjunction with a broad geochemical investigation during field-scale biostimulation and desorption experiments. This investigation was carried out in the uranium-contaminated alluvial aquifer of the Rifle field research site. In this well-characterized setting, a more comprehensive understanding of U isotope geochemistry is possible. Our results indicate that U isotope fractionation is consistently observed across multiple experiments at the Rifle site. Microbially-mediated reduction is suggested to account for most or all of the observed fractionation as abiotic reduction has been demonstrated to impart much smaller, often near-zero, isotopic fractionation or isotopic fractionation in the opposite direction. Data from some time intervals are consistent with a simple model for transport and U(VI) reduction, where the fractionation factor (ε = +0.65‰ to +0.85‰) is consistent with experimental studies. However, during other time intervals the observed patterns in our data indicate the importance of other processes in governing U concentrations and 238U/235U ratios. For instance, we demonstrate that departures from Rayleigh behavior in groundwater systems arise from the presence of adsorbed species. We also show that isotope data are sensitive to the onset of oxidation after biostimulation ends, even in the case where reduction continues to remove contaminant uranium downstream. Our study and the described conceptual model support the use of 238U/235U ratios as a tool for evaluating the efficacy of biostimulation and potentially other remedial strategies employed at Rifle and other uranium-contaminated sites.

  2. Fission Product Yield Study of 235U, 238U and 239Pu Using Dual-Fission Ionization Chambers

    Science.gov (United States)

    Bhatia, C.; Fallin, B.; Howell, C.; Tornow, W.; Gooden, M.; Kelley, J.; Arnold, C.; Bond, E.; Bredeweg, T.; Fowler, M.; Moody, W.; Rundberg, R.; Rusev, G.; Vieira, D.; Wilhelmy, J.; Becker, J.; Macri, R.; Ryan, C.; Sheets, S.; Stoyer, M.; Tonchev, A.

    2014-05-01

    To resolve long-standing differences between LANL and LLNL regarding the correct fission basis for analysis of nuclear test data [M.B. Chadwick et al., Nucl. Data Sheets 111, 2891 (2010); H. Selby et al., Nucl. Data Sheets 111, 2891 (2010)], a collaboration between TUNL/LANL/LLNL has been established to perform high-precision measurements of neutron induced fission product yields. The main goal is to make a definitive statement about the energy dependence of the fission yields to an accuracy better than 2-3% between 1 and 15 MeV, where experimental data are very scarce. At TUNL, we have completed the design, fabrication and testing of three dual-fission chambers dedicated to 235U, 238U, and 239Pu. The dual-fission chambers were used to make measurements of the fission product activity relative to the total fission rate, as well as for high-precision absolute fission yield measurements. The activation method was employed, utilizing the mono-energetic neutron beams available at TUNL. Neutrons of 4.6, 9.0, and 14.5 MeV were produced via the 2H(d,n)3He reaction, and for neutrons at 14.8 MeV, the 3H(d,n)4He reaction was used. After activation, the induced γ-ray activity of the fission products was measured for two months using high-resolution HPGe detectors in a low-background environment. Results for the yield of seven fission fragments of 235U, 238U, and 239Pu and a comparison to available data at other energies are reported. For the first time results are available for neutron energies between 2 and 14 MeV.

  3. Radiosensitization of Glioblastoma Cell Lines by the Dual PI3K and mTOR Inhibitor NVP-BEZ235 Depends on Drug-Irradiation Schedule12

    OpenAIRE

    Kuger, Sebastian; Graus, Dorothea; Brendtke, Rico; Günther, Nadine; Katzer, Astrid; Lutyj, Paul; Polat, Bülent; Chatterjee, Manik; Sukhorukov, Vladimir L.; Flentje, Michael; Djuzenova, Cholpon S.

    2013-01-01

    Previous studies have shown that the dual phosphatidylinositide 3-kinase/mammalian target of rapamycin (PI3K/mTOR) inhibitor NVP-BEZ235 radiosensitizes tumor cells if added shortly before ionizing radiation (IR) and kept in culture medium thereafter. The present study explores the impact of inhibitor and IR schedule on the radiosensitizing ability of NVP-BEZ235 in four human glioblastoma cell lines. Two different drug-IR treatment schedules were compared. In schedule I, cells were treated wit...

  4. 235例患者临终关怀现状调查及其影响因素分析%The Current Situation of Hospice Care and Influencing Factors in 235 Cases

    Institute of Scientific and Technical Information of China (English)

    辛爱利; 阎向东; 王彩燕

    2015-01-01

    Objective:To survey the level of hospice care and the influencing factors in Shaanxi province. Methods:Interview and return visit method was used to investigate. Results:In total 235 patients, 37. 02% patients received hos-pice care. There is not significant difference between hospice users and no hospice users in sex and geographic differ-ences. There was significant difference between hospice users and no hospice users in personal ages, and in gap between urban and rural areas. and in medical payment, and in basic lesions. Malignant tumor patients receive hospice care most-ly. No patient received hospice care patients with acute trauma. The effect of ages on hospice is maximum ( OR =2. 877). Basic lesions is an important cause of influence whether patients receiving hospice care services(OR=1. 569). Conclusion:The level of hospice care is low in Shaanxi. The age and basic lesions is influencing factors of hospice care. The geographic differences has no effect on hospice care.%目的:了解陕西地区临终关怀现状,分析其影响因素。方法采用门诊访谈和回访两种调查方法。结果在235例被调查患者中,37.02%的患者接受了临终关怀服务;患者在性别、所在地区两方面无显著性差异,在年龄、城乡差别、医疗付费方式方面存在显著性差异;基础病变明显影响临终关怀,恶性肿瘤患者接受临终关怀最多,急性外伤患者无1例接受临终关怀服务;年龄对临终关怀影响最大( OR=2.877);基础疾病则是影响患者是否接受临终关怀服务的重要原因( OR=1.569)。结论陕西地区临终关怀处于较低水平;年龄、基础疾病是影响临终关怀的因素;地域差别对临终关怀无影响。

  5. Redução da altura de plantas de soja causada pelo ácido 2,3,5-triiodobenzóico Height reduction in soybean plants caused by 2,3,5-triiodobenzoic acid

    Directory of Open Access Journals (Sweden)

    Stella Consorte Cato

    2006-06-01

    Full Text Available O ácido 2,3,5-triiodobenzóico (TIBA, um inibidor do transporte de auxina, quando aplicado via foliar, pode reduzir o crescimento vegetativo. Um dos problemas ainda enfrentado pelos produtores de soja é o acamamento da cultura no campo devido a crescimento vegetativo excessivo. Objetivando avaliar os efeitos do TIBA sobre o desenvolvimento e a produção de plantas de soja (Glycine max (L. Merrill cv. Pintado, realizou-se um experimento em casa de vegetação, no Departamento de Ciências Biológicas da ESALQ/USP. Em plantas envasadas, aplicou-se TIBA, via foliar, nas concentrações de 30, 40 e 50mg L-1, no estádio fenológico V5. Os parâmetros avaliados foram a altura das plantas, o número e a massa de vagens e grãos por planta e a massa de 100 sementes. O delineamento experimental foi inteiramente casualizado com 4 tratamentos e 6 repetições. Os dados obtidos foram submetidos à análise de variância e regressão polinomial. Verificou-se redução significativa na altura de plantas de soja tratadas com concentrações crescentes de TIBA, quando comparadas ao controle. O TIBA foi eficaz em reduzir a altura de plantas de soja, sem afetar negativamente parâmetros relacionados à produção.The 2,3,5-triiodobenzoic acid, an auxin transport inhibitor, when applied on leaves can reduce the vegetative growth. One of the problems faced by soybean producers is the lodging of the plants in the field due to excessive vegetative growth. Trying to evaluate the effects of TIBA over soybean (Glycine max (L. Merrill cv. Pintado vegetative growth and yield, an experiment was carried out in the greenhouse of the Department of Biological Sciences at ESALQ/USP. Using potted-plants, TIBA was sprayed on the leaves of soybean plants at 30, 40 and 50 g L-1, at V5 phenological stage. Plant height, number and mass of pods per plant and 100-grain mass were assessed. The experiment was completely randomized with 4 treatments and 6 replications. Data were

  6. Q235钢基体表面微晶玻璃功能梯度涂层的残余应力分析%Residual stress analysis in functionally gradient glass-ceramic coatings on Q235 steel

    Institute of Scientific and Technical Information of China (English)

    周黎明; 龚伟; 王恩泽; 韩腾

    2014-01-01

    运用ANSYS有限元软件对Q235钢/微晶玻璃梯度涂层复合材料在制备过程中产生的残余应力进行了数值模拟。建立了该复合材料的有限元分析模型,探讨了不同层数、层厚对该复合材料体系残余应力分布的影响。结果表明:在基体与梯度涂层的界面边缘处存在较大的应力集中;随着层数或层厚的增加,涂层表面最大径向残余压应力增大;梯度层数和涂层厚度对界面处的残余应力都有明显影响。此模拟分析结果可以为该梯度涂层复合材料的设计和制备提供理论依据和参考。%The residual stress of Q 235 steel/glass-ceramic gradient coatings was simulated with the commercial software ANSYS .The finite element analysis model of the composite was established and the distributions of residual stress in the composite system had been investigated based on various the layer numbers and the coating thickness .The results show that there is a remarkable stress concentration near the edge of the interface between substrate and coating .The maximum radial stress on the coating surface increase with the layer number or the coating thickness increasing .The layer numbers and the thickness of gradient coatings have a significant effect on the residual stress at the interface between substrate and coating .The simulation results can be used to provide theoretical guidance for the design and preparation of the composite.

  7. 41 CFR 102-73.235 - What is the maximum lease term that a Federal agency may agree to when it has been delegated...

    Science.gov (United States)

    2010-07-01

    ... lease term that a Federal agency may agree to when it has been delegated lease acquisition authority... ACQUISITION Acquisition by Lease Limitations on the Use of Delegated Authority § 102-73.235 What is the...)(2), agencies delegated the authorities outlined herein may enter into leases for the term specified...

  8. Prompt neutron multiplicity distribution for ~(235)U(n,f) at incident energies up to 20 MeV

    Institute of Scientific and Technical Information of China (English)

    陈永静; 刘廷进

    2011-01-01

    For the n+235U fission reaction, the total excitation energy partition of the fission fragments, the average neutron kinetic energy ε (A) and the total average energies Eˉγ(A) removed by γ rays as a function of fission fragment mass are given at incident

  9. Research on Prompt Neutron Multiplicity Distribution for the Neutron-Induced Fission of 235U at 14 MeV Neutrons

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The prompt neutron multiplicity distribution ν(A) for the n+ 235U fission system at 14 MeV was studied using the distribution mode of the excitation energy and the averaged γ-ray energy in the two

  10. Effect of imperfections of the radial component of a magnetic field on beam dynamics in medical cyclotron C235-V3

    Science.gov (United States)

    Karamysheva, G. A.; Kostromin, S. A.; Morozov, N. A.; Samsonov, E. V.; Syresin, E. M.

    2014-11-01

    This paper presents numerical simulations and experimental results related to the effect of imperfections of the radial component of a magnetic field on the beam dynamics in the medical cyclotron C235-V3 of the Dimitrovgrad Proton Therapy Center. These imperfections in the region of the minimal axial betatron frequency lead to a transformation of coherent motion of the center of gravity of the beam to the incoherent motion of separate particles. The radial component increases the axial size of the beam by a factor of 2 at a radius of 20 cm, which produces additional losses of protons. To reduce undesirable actions of the radial component on the axial motion, the magnetic system in the central region has been optimized using two procedures: the positioning of shim correctors on sectors and selecting a special asymmetric arrangement of the upper and lower central plugs. This led to a twofold reduction in the axial size of the beam and a decrease in proton losses. Eventually, the beam transmission in C235-V3 has been increased to 72% without a limiting aperture diaphragm, which is commonly used in cyclotrons of this type. This makes it possible to reduce the irradiation dose of machine elements and increase the beam current at a deflector entrance of the cyclotron C235-V3 by a factor of 1.5 when compared to a serial C235 cyclotron.

  11. High resolution study of U235(nsub(th),f) and Th229(nsub(th), f) with Cosi Fan Tutte mass spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Sicre, A.; Barreau, G.; Boukellal, A.

    1986-01-01

    The new built Cosi Fan Tutte facility installed at the High Flux Reactor of the ILL in Grenoble was used to obtain correlated mass, kinetic energy and nuclear charge of the fission fragments from U235(nsub(th),f) and Th229(nsub(th),f).

  12. Non-destructive field measurement of the ratio /sup 235/U//sup 238/U in depleted to moderately enriched uranium

    Energy Technology Data Exchange (ETDEWEB)

    Balagna, J.P.; Cowan, G.A.

    1977-01-01

    The exploration of a natural reactor site is expedited by prompt measurement of /sup 235/U to /sup 238/U ratios near the mining operation. An instrument has been constructed which uses the relative fission rates of /sup 235/U and /sup 238/U in fast and moderated neutron spectra to measure the isotopic ratio. This device can be placed in the field and allows continuous monitoring of ore as a rich deposit of uranium is mined. With rapid return of isotopic information to the operator it is possible to locate a fossil reactor before it has been destroyed. The relative fast neutron and slow neutron fission rates induced in uranium which is depleted to moderately enriched in /sup 235/U may be used to measure the isotopic ratio /sup 235/U//sup 238/U quickly and nondestructively with a relative error of a few percent. When a neutron source such as /sup 252/Cf is used, the measurements may be made in the field.

  13. 41 CFR 102-118.235 - Must my agency keep physical control and accountability of the GBL and GTR forms or GBL and GTR...

    Science.gov (United States)

    2010-07-01

    ... physical control and accountability of the GBL and GTR forms or GBL and GTR numbers? 102-118.235 Section... accountability of the GBL and GTR forms or GBL and GTR numbers? Yes, your agency is responsible for the physical control and accountability of the GBL and GTR stock and must have procedures in place and available...

  14. 用N235从富铁高酸度硫酸浸出液中萃取除铁%Removal of Fe3+ from iron rich and high acidity sulfuric acid leaching liquid by extraction of N235

    Institute of Scientific and Technical Information of China (English)

    张魁芳; 刘志强; 曹洪杨; 邱显扬

    2015-01-01

    The extraction of Fe 3+ by N235 was studied based on the technology gap on the removal of Fe3+ from iron rich and high acidity sulfuric acid leaching liquid by extraction. The effects of H2O2 dosage, feed initial pH, extractant concentration, extractant composition and extraction time on the extraction, and the effects of H2SO4 concentration and tripping time on the stripping were investigated. The cross current extraction process was designed and the isotherms of stripping were plotted, and the conditions of extractant transformation were researched. The results show that, when 30% (mass fraction) H2O2 dosage is 3.85 times of theoretical one, Fe2+ can be oxidized into Fe3+ totally, and with 30% (volume fraction) N235 and10% (volume fraction) TBP in sulphonated kerosene as extractant, the extraction rate of Fe3+ from the solution with initial pH of 0.11reaches 96.67% in four-stage cross current extraction with O/A ratio of 1:1 (volume ratio of oil phase to aqueous phase) at 25℃ for 2 min, and the loss rate of Cu2+, Co2+, Ni2+ are 3.04%, 1.39%, 3.84%, respectively. The Fe3+ in loaded organic can be stripped into Fe2(SO4)3 with purity of 98.87% using 0.3 mol/L H2SO4 solution and the stripping rate reaches 99.12% in two-stage counter current stripping with O/A ratio of 1:1 (volume ratio of oil phase to aqueous phase) at 25℃ for 6 min. After stripping, the acid in loaded organic phase can be neutralized using Na2CO3. The organic phase returns to extraction circularly.%对N235萃取除铁进行研究,考察H 2 O 2用量、料液初始pH、萃取剂浓度、萃取剂组成、萃取时间对萃取的影响以及H2SO4浓度、反萃时间对反萃的影响,设计错流萃取过程并绘制反萃平衡等温线,对萃取剂转型条件进行研究。结果表明:H 2 O 2用量为理论量3.85倍时可将Fe2+完全氧化成Fe3+,并采用有机相组成30%(体积分数)N235+10%(体积分数)TBP+磺化煤油作为萃取剂,料液初始pH为0.11,其最佳萃

  15. 氧化硫硫杆菌和芽孢杆菌协作下Q235钢腐蚀行为%Corrosion behavior of steel Q235 co-influenced by Thiobacillus thiooxidans and Bacillus

    Institute of Scientific and Technical Information of China (English)

    杜娟; 李松梅; 刘建华; 于美

    2014-01-01

    采用表面分析技术、失重法和电化学测试技术研究了Q235钢在氧化硫硫杆菌(T.t,Thiobacillus thiooxidans)和芽孢杆菌(Bacillus)协同作用下的腐蚀行为.扫描电镜结果表明,与单菌体系相比,混菌体系会形成最为致密的生物膜;混菌体系中浸泡的试样表面会出现不同于单菌体系的圆形蚀坑.腐蚀失重结果表明,混菌中试样的腐蚀速率介于2个单菌体系之间.交流阻抗结果表明,混菌体系浸泡2天后试样表面出现2个时间常数,表面膜层电阻经历了先增大后减小的过程.

  16. Investigating Uranium Mobility Using Stable Isotope Partitioning of 238U/235U and a Reactive Transport Model

    Science.gov (United States)

    Bizjack, M.; Johnson, T. M.; Druhan, J. L.; Shiel, A. E.

    2015-12-01

    We report a numerical reactive transport model which explicitly incorporates the effectively stable isotopes of uranium (U) and the factors that influence their partitioning in bioactive systems. The model reproduces trends observed in U isotope ratios and concentration measurements from a field experiment, thereby improving interpretations of U isotope ratios as a tracer for U reactive transport. A major factor contributing to U storage and transport is its redox state, which is commonly influenced by the availability of organic carbon to support metal-reducing microbial communities. Both laboratory and field experiments have demonstrated that biogenic reduction of U(VI) fractionates the stable isotope ratio 238U/235U, producing an isotopically heavy solid U(IV) product. It has also been shown that other common reactive transport processes involving U do not fractionate isotopes to a consistently measurable level, which suggests the capacity to quantify the extent of bioreduction occurring in groundwater containing U using 238U/235U ratios. A recent study of a U bioremediation experiment at the Rifle IFRC site (Colorado, USA) applied Rayleigh distillation models to quantify U stable isotope fractionation observed during acetate amendment. The application of these simplified models were fit to the observations only by invoking a "memory-effect," or a constant source of low-concentration, unfractionated U(VI). In order to more accurately interpret the measured U isotope ratios, we present a multi-component reactive transport model using the CrunchTope software. This approach is capable of quantifying the cycling and partitioning of individual U isotopes through a realistic network of transport and reaction pathways including reduction, oxidation, and microbial growth. The model incorporates physical heterogeneity of the aquifer sediments through zones of decreased permeability, which replicate the observed bromide tracer, major ion chemistry, U concentration, and U

  17. SYNERGISM EFFECT OF THIOBACILLUS FERROOXIDANS AND THIOBACILLUS THIOOXIDAN ON THE CORROSION BEHAVIOR OF STEEL Q235%氧化亚铁硫杆菌和氧化硫硫杆菌的协同作用对Q235钢腐蚀行为的影响

    Institute of Scientific and Technical Information of China (English)

    李松梅; 王彦卿; 刘建华; 梁馨

    2009-01-01

    采用失重法、交流阻抗测试和扫描电镜等手段研究了氧化亚铁硫杆菌(T.f)和氧化硫硫杆菌(T.t)的协同作用对Q235钢腐蚀行为的影响.结果表明,T.f和T.t的协同作用加剧了Q235钢的均匀腐蚀速率,混合菌体系中Q235钢的腐蚀失重远大于两种微生物单独存在体系.显微分析结果表明,T.t体系中金属没有出现点蚀,混合菌体系中Q235钢的点蚀坑较T.f体系中的小而浅,T.t的存在降低了Q235钢的局部腐蚀.

  18. Production of actinium-225 for alpha particle mediated radioimmunotherapy.

    Science.gov (United States)

    Boll, Rose A; Malkemus, Dairin; Mirzadeh, Saed

    2005-05-01

    The initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the alpha emitter (213)Bi in killing cancer cells. Bismuth-213 is obtained from a radionuclide generator system from decay of 10-days (225)Ac parent. Recent pre-clinical studies have also shown the potential application of both (213)Bi, and the (225)Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy. This paper describes our five years of experience in production of (225)Ac in partial support of the on-going clinical trials. A four-step chemical process, consisting of both anion and cation exchange chromatography, is utilized for routine separation of carrier-free (225)Ac from a mixture of (228)Th, (229)Th and (232)Th. The separation of Ra and Ac from Th is achieved using the marcoporous anion exchange resin MP1 in 8M HNO(3) media. Two sequential MP1/NO(3) columns provide a separation factor of approximately 10(6) for Ra and Ac from Th. The separation of Ac from Ra is accomplished on a low cross-linking cation exchange resin AG50-X4 using 1.2M HNO(3) as eluant. Two sequential AG50/NO(3) columns provide a separation factor of approximately 10(2) for Ac from Ra. A 60-day processing schedule has been adopted in order to reduce the processing cost and to provide the highest levels of (225)Ac possible. Over an 8-week campaign, a total of approximately 100 mCi of (225)Ac (approximately 80% of the theoretical yield) is shipped in 5-6 batches, with the first batch typically consisting of approximately 50 mCi. After the initial separation and purification of Ac, the Ra pool is re-processed on a bi-weekly schedule or as needed to provide smaller batches of (225)Ac. The averaged radioisotopic purity of the (225)Ac was 99.6 +/- 0.7% with a (225)Ra content of < or =0.6%, and an average (229)Th content of (4(-4)(+5)) x 10(-5)%.

  19. Isolation of Actinium from Neutron-irradiated Thorium-I

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    Isolation of Actinium from Neutron-irradiated Thorium-I¥YangWeifan;YuanShuanggui;MuWantong;ZhangXueqian;LiZhongweiandZhaoLili...

  20. Absorbance detector for high performance liquid chromatography based on a deep-UV light-emitting diode at 235nm.

    Science.gov (United States)

    da Silveira Petruci, João Flavio; Liebetanz, Michael G; Cardoso, Arnaldo Alves; Hauser, Peter C

    2017-08-25

    In this communication, we describe a flow-through optical absorption detector for HPLC using for the first time a deep-UV light-emitting diode with an emission band at 235nm as light source. The detector is also comprised of a UV-sensitive photodiode positioned to enable measurement of radiation through a flow-through cuvette with round aperture of 1mm diameter and optical path length of 10mm, and a second one positioned as reference photodiode; a beam splitter and a power supply. The absorbance was measured and related to the analyte concentration by emulating the Lambert-Beer law with a log-ratio amplifier circuitry. This detector showed noise levels of 0.30mAU, which is comparable with our previous LED-based detectors employing LEDs at 280 and 255nm. The detector was coupled to a HPLC system and successfully evaluated for the determination of the anti-diabetic drugs pioglitazone and glimepiride in an isocratic separation and the benzodiazepines flurazepam, oxazepam and clobazam in a gradient elution. Good linearities (r>0.99), a precision better than 0.85% and limits of detection at sub-ppm levels were achieved. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Experimental and Numerical Investigations of Fretting Fatigue Behavior for Steel Q235 Single-Lap Bolted Joints

    Directory of Open Access Journals (Sweden)

    Yazhou Xu

    2016-01-01

    Full Text Available This work aims to investigate the fretting fatigue life and failure mode of steel Q235B plates in single-lap bolted joints. Ten specimens were prepared and tested to fit the S-N curve. SEM (scanning electron microscope was then employed to observe fatigue crack surfaces and identify crack initiation, crack propagation, and transient fracture zones. Moreover, a FEM model was established to simulate the stress and displacement fields. The normal contact stress, tangential contact stress, and relative slipping displacement at the critical fretting zone were used to calculate FFD values and assess fretting fatigue crack initiation sites, which were in good agreement with SEM observations. Experimental results confirmed the fretting fatigue failure mode for these specimens. It was found that the crack initiation resulted from wear regions at the contact surfaces between plates, and fretting fatigue cracks occurred at a certain distance away from hole edges. The proposed FFD-N relationship is an alternative approach to evaluate fretting fatigue life of steel plates in bolted joints.

  2. Calculation of the absolute detection efficiency of a moderated /sup 235/U neutron detector on the Tokamak Fusion Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Ku, L.P.; Hendel, H.W.; Liew, S.L.

    1989-02-01

    Neutron transport simulations have been carried out to calculate the absolute detection efficiency of a moderated /sup 235/U neutron detector which is used on the TFTR as a part of the primary fission detector diagnostic system for measuring fusion power yields. Transport simulations provide a means by which the effects of variations in various shielding and geometrical parameters can be explored. These effects are difficult to study in calibration experiments. The calculational model, benchmarked against measurements, can be used to complement future detector calibrations, when the high level of radioactivity resulting from machine operation may severely restrict access to the tokamak. We present a coupled forward-adjoint algorithm, employing both the deterministic and Monte Carlo sampling methods, to model the neutron transport in the complex tokamak and detector geometries. Sensitivities of the detector response to the major and minor radii, and angular anisotropy of the neutron emission are discussed. A semi-empirical model based on matching the calculational results with a small set of experiments produces good agreement (+-15%) for a wide range of source energies and geometries. 20 refs., 6 figs., 4 tabs.

  3. Effect of U-238 and U-235 cross sections on nuclear characteristics of fast and thermal reactors

    Energy Technology Data Exchange (ETDEWEB)

    Akie, Hiroshi; Takano, Hideki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kaneko, Kunio

    1997-03-01

    Benchmark calculation has been made for fast and thermal reactors by using ENDF/B-VI release 2(ENDF/B-VI.2) and JENDL-3.2 nuclear data. Effective multiplication factors (k{sub eff}s) calculated for fast reactors calculated with ENDF/B-VI.2 becomes about 1% larger than the results with JENDL-3.2. The difference in k{sub eff} is caused mainly from the difference in inelastic scattering cross section of U-238. In all thermal benchmark cores, ENDF/B-VI.2 gives smaller multiplication factors than JENDL-3.2. In U-235 cores, the difference is about 0.3%dk and it becomes about 0.6% in TCA U cores. The difference in U-238 data is also important in thermal reactors, while there are found 0.1-0.3% different v values of U isotopes in thermal energy between ENDF/B-VI.2 and JENDL-3.2. (author)

  4. Design of a high-flux epithermal neutron beam using 235U fission plates at the Brookhaven Medical Research Reactor.

    Science.gov (United States)

    Liu, H B; Brugger, R M; Rorer, D C; Tichler, P R; Hu, J P

    1994-10-01

    Beams of epithermal neutrons are being used in the development of boron neutron capture therapy for cancer. This report describes a design study in which 235U fission plates and moderators are used to produce an epithermal neutron beam with higher intensity and better quality than the beam currently in use at the Brookhaven Medical Research Reactor (BMRR). Monte Carlo calculations are used to predict the neutron and gamma fluxes and absorbed doses produced by the proposed design. Neutron flux measurements at the present epithermal treatment facility (ETF) were made to verify and compare with the computed results where feasible. The calculations indicate that an epithermal neutron beam produced by a fission-plate converter could have an epithermal neutron intensity of 1.2 x 10(10) n/cm2.s and a fast neutron dose per epithermal neutron of 2.8 x 10(-11) cGy.cm2/nepi plus being forward directed. This beam would be built into the beam shutter of the ETF at the BMRR. The feasibility of remodeling the facility is discussed.

  5. Neutron yield and induced radioactivity: a study of 235-MeV proton and 3-GeV electron accelerators.

    Science.gov (United States)

    Hsu, Yung-Cheng; Lai, Bo-Lun; Sheu, Rong-Jiun

    2016-01-01

    This study evaluated the magnitude of potential neutron yield and induced radioactivity of two new accelerators in Taiwan: a 235-MeV proton cyclotron for radiation therapy and a 3-GeV electron synchrotron serving as the injector for the Taiwan Photon Source. From a nuclear interaction point of view, neutron production from targets bombarded with high-energy particles is intrinsically related to the resulting target activation. Two multi-particle interaction and transport codes, FLUKA and MCNPX, were used in this study. To ensure prediction quality, much effort was devoted to the associated benchmark calculations. Comparisons of the accelerators' results for three target materials (copper, stainless steel and tissue) are presented. Although the proton-induced neutron yields were higher than those induced by electrons, the maximal neutron production rates of both accelerators were comparable according to their respective beam outputs during typical operation. Activation products in the targets of the two accelerators were unexpectedly similar because the primary reaction channels for proton- and electron-induced activation are (p,pn) and (γ,n), respectively. The resulting residual activities and remnant dose rates as a function of time were examined and discussed.

  6. Preliminary results on ^241,243Am and ^235U (n,γ) cross sections measured at DANCE

    Science.gov (United States)

    Jandel, M.; Bredeweg, T. A.; Fowler, M. M.; Bond, E. M.; O'Donnell, J. M.; Reifarth, R.; Rundberg, R. S.; Ullmann, J. L.; Vieira, D. J.; Wilhelmy, J. B.; Wouters, J. M.; Macri, R. A.; Wu, C.-Y.; Becker, J. A.

    2006-10-01

    The Detector for Advanced Neutron Capture Experiments (DANCE) at Los Alamos National Laboratory (LANL) was used for neutron capture cross sections measurements. Its high granularity of 160 BaF2 detectors allows for highly efficient detection of prompt gamma-rays following a neutron capture. DANCE is located on the 20.26 m neutron flight path 14 at the Manuel Lujan Jr. Neutron Scattering Center at the Los Alamos Neutron Science Center (LANSCE). The moderated production target provides neutrons in the 0.02 eV - 500 keV energy range. An analysis of neutron capture measurements on ^241,243Am and ^235U targets will be presented. The experiments were carried out using a customized Parallel-Plate Avalanche Counter (PPAC) detector installed in the center of the DANCE array. The PPAC was used as a fission-tagging detector to separate (n,γ) from (n,fission) events. Preliminary results of (n,γ) cross sections will be presented and compared with the available evaluated data for neutron energies from 0.02 eV to 1 keV. Additional neutron capture measurements with DANCE will be briefly discussed.

  7. The adsorption and inhibition effect of calcium lignosulfonate on Q235 carbon steel in simulated concrete pore solution

    Science.gov (United States)

    Wang, Yishan; Zuo, Yu; Zhao, Xuhui; Zha, Shanshan

    2016-08-01

    The corrosion inhibition of calcium lignosulfonate (CLS) for Q235 carbon steel in saturated Ca(OH)2 + 0.1 mol/L NaCl solution was studied by means of weight loss, polarization, fluorescence microscopy (FM), scanning electron microscopy/energy dispersive spectrometry (SEM/EDS), microscopic infrared spectral imaging (M-IR) and X-ray photoelectron spectroscopy (XPS). For the steel in simulated concrete pore solution (pH 12.6), an increase of Eb value and a decrease of icorr value occurred with different concentrations of CLS. The optimal content of CLS was 0.001 mol/L at which the inhibition rate was 98.86% and the Eb value increased to 719 mV after 10 h of immersion. In mortar solution and in reinforced concrete environment, CLS also showed good inhibition for steel. The preferential adsorption of CLS around pits was detected by M-IR. The result illustrates that at the early stage the adsorption of CLS was heterogeneous and CLS may have a competitive adsorption with chloride ions at the active sites, which would be beneficial for decreasing the susceptibility of pitting corrosion. After the pre-filming time, an intact adsorption CLS film formed on carbon steel surface. The adsorption between CLS and calcium presented as Casbnd Osbnd S bonds. The adsorption of CLS on carbon steel surface occurred probably by both physisorption and chemisorption.

  8. Determination of Nuclear Charge Distributions of Fission Fragments from ^{235}U (n_th, f) with Calorimetric Low Temperature Detectors

    Science.gov (United States)

    Grabitz, P.; Andrianov, V.; Bishop, S.; Blanc, A.; Dubey, S.; Echler, A.; Egelhof, P.; Faust, H.; Gönnenwein, F.; Gomez-Guzman, J. M.; Köster, U.; Kraft-Bermuth, S.; Mutterer, M.; Scholz, P.; Stolte, S.

    2016-08-01

    Calorimetric low temperature detectors (CLTD's) for heavy-ion detection have been combined with the LOHENGRIN recoil separator at the ILL Grenoble for the determination of nuclear charge distributions of fission fragments produced by thermal neutron-induced fission of ^{235}U. The LOHENGRIN spectrometer separates fission fragments according to their mass-to-ionic-charge ratio and their kinetic energy, but has no selectivity with respect to nuclear charges Z. For the separation of the nuclear charges, one can exploit the nuclear charge-dependent energy loss of the fragments passing through an energy degrader foil (absorber method). This separation requires detector systems with high energy resolution and negligible pulse height defect, as well as degrader foils which are optimized with respect to thickness, homogeneity, and energy loss straggling. In the present, contribution results of test measurements at the Maier Leibnitz tandem accelerator facility in Munich with ^{109}Ag and ^{127}I beams with the aim to determine the most suitable degrader material, as well as measurements at the Institut Laue-Langevin will be presented. These include a systematic study of the quality of Z-separation of fission fragments in the mass range 82le A le 132 and a systematic measurement of ^{92}Rb fission yields, as well as investigations of fission yields toward the symmetry region.

  9. Star formation black hole growth and dusty tori in the most luminous AGNs at z=2-3.5

    CERN Document Server

    Netzer, Hagai; Nordon, Raanan; Trakhtenbrot, Benny; Lira, Paulina; Shemmer, Ohad

    2015-01-01

    We report herschel observations of 100 very luminous, optically selected AGNs at z=2-3.5 with log(LUV)(erg/sec)> 46.5, where LUV=L1350A. The distribution in LUV is similar to the general distribution of SDSS AGNs in this redshift and luminosity interval. We measured SF luminosity, LSF, and SFR in 34 detected sources by fitting combined SF and WISE-based torus templates. We also obtained statistically significant stacks for the undetected sources in two luminosity groups. The sample properties are compared with those of very luminous AGNs at z>4.5. The main findings are: 1) The mean and the median SFRs of the detected sources are 1176 and 1010 Msun/yr, respectively. The mean SFR of the undetected sources is 148 Msun/yr. The ratio of SFR to BH accretion rate is approximately 80 for the detected sources and less than 10 for the undetected sources. There is no difference in LAGN and only a very small difference in L(torus) between detected and undetected sources. 2) The redshift distribution of LSF and LAGN for t...

  10. Numerical simulation of stress distribution in Al2 O3-TiC/Q235 diffusion bonded joints

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    The distributions of the axial stress and shear stress in Al2O3-TiC/Q235 diffusion bonded joints were studied using finite element method (FEM). The effect of interlayer thickness on the axial stress and shear stress was also investigated. The results indicate that the gradients of the axial stress and shear stress are great near the joint edge. The maximal shear stress produces at the interface of the Al2O3-TiC and Ti interlayer. With the increase of Cu interlayer thickness, the magnitudes of the axial stress and shear stress first decrease and then increase. The distribution of the axial stress changes greatly with a little change in the shear stress. The shear fracture initiates at the interface of the Al2O3-TiC/ Ti interlayer with high shear stress and then propagates to the Al2O3-TiC side, which is consistent with the stress FEM calculating results.

  11. Feasibility study of U-235, Pu-239 and Pu-240 content determination in an irradiated fuel by neutron transmission analysis

    Energy Technology Data Exchange (ETDEWEB)

    Naguib, K.; Michaiel, M.L.; Morcos, H.N

    1998-07-01

    A proposed nondestructive method and its feasibility for the determination of U-235, Pu-239 and Pu-240 contents in an irradiated fuel is described. The method is based on the use of shape fit analysis of the Time-Of-Flight (TOF) neutron transmission data of the irradiated fuel for neutron energies below 3 eV. The neutron transmission experiment of the irradiated fuel is planned to carry out using one of the TOF spectrometers installed at ET-RR-1 reactor. The computer code SHAPE is adapted taking into account the known parameters of resonances of certain fissile and fission product nuclei to provide the fit analysis. The content of the gross-fissile and fission product isotopes are determined from the burn-up calculations of the fuel assembly of the ET-RR-1 reactor with defined history. The effect of both uncertainties in resonance parameters on the deduced contents of fissile nuclei and statistical accuracy of the TOF measurements are estimated.

  12. Photo-fission Product Yield Measurements at Eγ=13 MeV on 235U, 238U, and 239Pu

    Science.gov (United States)

    Tornow, W.; Bhike, M.; Finch, S. W.; Krishichayan, Fnu; Tonchev, A. P.

    2016-09-01

    We have measured Fission Product Yields (FPYs) in photo-fission of 235U, 238U, and 239Pu at TUNL's High-Intensity Gamma-ray Source (HI γS) using mono-energetic photons of Eγ = 13 MeV. Details of the experimental setup and analysis procedures will be discussed. Yields for approximately 20 fission products were determined. They are compared to neutron-induced FPYs of the same actinides at the equivalent excitation energies of the compound nuclear systems. In the future photo-fission data will be taken at Eγ = 8 . 0 and 10.5 MeV to find out whether photo-fission exhibits the same so far unexplained dependence of certain FPYs on the energy of the incident probe, as recently observed in neutron-induced fission, for example, for the important fission product 147Nd. Work supported by the U. S. Dept. of Energy, under Grant No. DE-FG02-97ER41033, and by the NNSA, Stewardship Science Academic Alliances Program, Grant No. DE-NA0001838 and the Lawrence Livermore, National Security, LLC under Contract No. DE-AC52-07NA27344.

  13. Q235结构钢低周多轴疲劳寿命评估方法的实验研究%Experimental research on life evaluation for low cycle multiaxial fatigue of Q235 steel

    Institute of Scientific and Technical Information of China (English)

    张小元; 张克实; 黄世鸿; 顾思远

    2013-01-01

    对建筑用Q235结构钢分别在单轴和多轴载荷下进行低周疲劳试验,并利用测得的试验结果对寿命评估方法进行研究。研究结果表明:在相同Von Mises等效应变幅值下,材料的比例拉扭路径疲劳寿命高于单轴拉压疲劳寿命,而非比例路径疲劳寿命低于单轴拉压疲劳寿命。按等效应变法进行寿命预测,在非比例加载路径下的预测结果远远超出2倍寿命安全范围区;按临界面法的KBM和Socie模型进行寿命预测能够得到较好的结果,但对圆形路径的高应变幅区得到的结果则过高估计了材料的寿命。在考虑循环过程临界面法向应变影响的基础上,提出了一个改进的考虑临界面拉伸影响的模型,其对比例和非比例路径循环下低周疲劳寿命的评估与实测吻合较好。%Low cycle fatigue tests on Q235 steel under uniaxial and multiaxial loadings were conduc-ted, and the fatigue life evaluation formulas were studied based on experiments .The low-cycle ex-perimental results of strain show that the fatigue life of the metal under proportionally multiaxial load -ing is longer than that under uniaxial loading , but the fatigue life of the metal under non-proportion-ally multiaxial loading is shorter under the condition of given Von Mises'equivalent strain amplitude controlled by machine .Using the equivalent strain approach to evaluate the low-cycle fatigue life, it can be found that the life value under non-proportionally multiaxial loading was 2 times larger than that given in the experiments .Adopting KBM or Socie model of the critical plane approach , al-though the life prediction become better evidently , over estimation is still inevitable for the low-cycle fatigue under round loading path with large strain amplitude .Based on the consideration of the ten-sion effect on normal of the critical plane during the cycle , a modified critical plane model is pro-posed, in which the tension factor

  14. Q235钢在扭转载荷作用下的磁化反转效应%Magnetizing Reversion Effect under Torsion Action of Q235 Steel

    Institute of Scientific and Technical Information of China (English)

    任尚坤; 黄隐; 习小文; 赵珍燕; 段振霞

    2016-01-01

    The metal magnetic memory technology is a recently developed new NDT method capable of the early detection of damages in test piece.Study on the magnetization reversal effect is to understand the basic principle of magnetic memory testing technology and to solve its application bottlenecks.By repeatedly loading-unloading the Q235 mild steel specimens under different torques,the magnetization value at surface fixed point was measured together with corresponding torques.The results show that at the elastic stage the magnetic flux density B shows approximately linear relationship with torque T.When the torque T reaches or exceeds the yield torque (39.98 N•m),the relationship between them performs as increasing first and then decreasing.With the yield process transferring to the center,the gap magnetic flux densityΔB is further opened.After approaching the tensile torque,the amount of change in magnetic flux density ΔB is further increased.Test shows that there exists the magnetizing reversion effect in the specimen magnetic flux density under the effect of torque,and it may provide basis for the evaluation of the stress-magnetism relationship in the course of torsion action.%磁记忆检测技术是近期发展起来的可早期发现金属检测试件损伤的新的无损检测方法,研究磁化反转效应可以解决磁记忆检测技术中的基础问题和应用瓶颈.通过反复地加载和卸载,测量了 Q235低碳钢试件在不同的扭矩作用下,表面固定点磁感应强度随扭矩变化的对应关系.试验结果表明,在弹性阶段,磁感应强度B 与扭矩T 近似成直线关系.当扭矩T 达到或超过屈服扭矩(39.98 N•m)之后,磁感应强度B 与扭矩T 的关系表现为先增大后减小.随着屈服过程向圆心的转移,磁感应强度差值ΔB 的差距进一步加大.在接近抗拉扭矩后,磁感应强度差值ΔB的变化量进一步增大.试验得出:试件的磁感应强度在扭矩作用下,

  15. 235 ORIGINAL ARTICLE

    African Journals Online (AJOL)

    boaz

    profiles and prevalence of MRSA and ESBL producers among wound bacterial isolates from a tertiary hospital in Ibadan. City. .... medical materials, surgical equipments and use of poorly or non ..... disinfection, good nursing practice and good.

  16. Comment: 235 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available u University (currently National Research Institute of Brewing)) licensed under CC Attribution2.1 Japan 撮影: ...水谷治(東北大学(現 酒類総研)) Photo: Osamu Mizutani (Tohoku University (currently National Research Institute of Brewing)) bando 2010/08/04 09:28:07 2010/08/04 11:18:35 ...

  17. RETRACTED: Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy.

    Science.gov (United States)

    Tang, Wenzhuang; Zhou, Tian-Biao; Jiang, Zongpei

    2015-12-01

    This article has been included in a multiple retraction: Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 This article has been retracted at the request of the Editors and the Publisher. After conducting a thorough investigation, SAGE found that the submitting authors of a number of papers published in the Journal of the Renin-Angiotensin Aldosterone System ( JRAAS) (listed below) had supplied fabricated contact details for their nominated reviewers. The Editors accepted these papers based on the reports supplied by the individuals using these fake reviewer email accounts. After concluding that the peer review process was therefore seriously compromised, SAGE and the journal Editors have decided to retract all affected articles. Online First articles (these articles will not be published in an issue) Wenzhuang Tang, Tian-Biao Zhou, and Zongpei Jiang Association of the angiotensinogen M235T gene polymorphism with risk of diabetes mellitus developing into diabetic nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563426, first published on December 18, 2014 doi: 10.1177/1470320314563426 Tian-Biao Zhou, Hong-Yan Li, Zong-Pei Jiang, Jia-Fan Zhou, Miao-Fang Huang, and Zhi-Yang Zhou Role of renin-angiotensin-aldosterone system inhibitors in radiation nephropathy Journal of Renin-Angiotensin-Aldosterone System 1470320314563424, first published on December 18, 2014 doi: 10.1177/1470320314563424 Weiqiang Zhong, Zongpei Jiang, and Tian-Biao Zhou Association between the ACE I/D gene polymorphism and T2DN susceptibility: The risk of T2DM developing into T2DN in the Asian population Journal of Renin-Angiotensin-Aldosterone System 1470320314566019, first published on January 26, 2015 doi: 10

  18. Autoimmune Conditions in 235 Hemochromatosis Probands with HFE C282Y Homozygosity and Their First-Degree Relatives

    Directory of Open Access Journals (Sweden)

    James C. Barton

    2015-01-01

    Full Text Available We performed a retrospective study of autoimmune conditions (ACs in 235 hemochromatosis probands at diagnosis by analyzing age, sex, ACs, history of first-degree family members with ACs (FH, diabetes, heavy ethanol consumption, elevated serum ALT/AST, nonalcoholic fatty liver disease, viral hepatitis, cirrhosis, iron removed to achieve iron depletion (QFe, and positivity for human leukocyte antigen (HLA haplotypes A∗01, B∗08; A∗02, B∗44; A∗03, B∗07; A∗03, B∗14; and A∗29, B∗44. There were 138 men (58.7%. Median followup was 19.6 y. One or more of 19 ACs were diagnosed in each of 35 probands (14.9%. Prevalences of Hashimoto’s thyroiditis, rheumatoid arthritis, and ankylosing spondylitis were 8.1% (95% CI: [5.1, 12.5], 1.7% [0.6, 4.6], and 0.0085 [0.0015, 0.0337], respectively. Eighteen probands (7.7% had a FH. Eight probands with ACs had 9 family members with ACs. In a logistic regression, ACs were less likely in men (odds ratio (OR 0.3 [0.1, 0.6] and more likely in probands with a FH (OR 4.1 [1.4, 11.8]. Overall ACs risk was not significantly associated with QFe or HLA haplotypes. Estimated survival of probands with and without ACs did not differ significantly. We conclude that ACs are common in hemochromatosis probands, especially women and probands with a FH.

  19. Autoimmune Conditions in 235 Hemochromatosis Probands with HFE C282Y Homozygosity and Their First-Degree Relatives.

    Science.gov (United States)

    Barton, James C; Barton, J Clayborn

    2015-01-01

    We performed a retrospective study of autoimmune conditions (ACs) in 235 hemochromatosis probands at diagnosis by analyzing age, sex, ACs, history of first-degree family members with ACs (FH), diabetes, heavy ethanol consumption, elevated serum ALT/AST, nonalcoholic fatty liver disease, viral hepatitis, cirrhosis, iron removed to achieve iron depletion (QFe), and positivity for human leukocyte antigen (HLA) haplotypes A (∗) 01, B (∗) 08; A (∗) 02, B (∗) 44; A (∗) 03, B (∗) 07; A (∗) 03, B (∗) 14; and A (∗) 29, B (∗) 44. There were 138 men (58.7%). Median followup was 19.6 y. One or more of 19 ACs were diagnosed in each of 35 probands (14.9%). Prevalences of Hashimoto's thyroiditis, rheumatoid arthritis, and ankylosing spondylitis were 8.1% (95% CI: [5.1, 12.5]), 1.7% [0.6, 4.6], and 0.0085 [0.0015, 0.0337], respectively. Eighteen probands (7.7%) had a FH. Eight probands with ACs had 9 family members with ACs. In a logistic regression, ACs were less likely in men (odds ratio (OR) 0.3 [0.1, 0.6]) and more likely in probands with a FH (OR 4.1 [1.4, 11.8]). Overall ACs risk was not significantly associated with QFe or HLA haplotypes. Estimated survival of probands with and without ACs did not differ significantly. We conclude that ACs are common in hemochromatosis probands, especially women and probands with a FH.

  20. Delayed Fission Gamma-ray Characteristics of Th-232 U-233 U-235 U-238 and Pu-239

    Energy Technology Data Exchange (ETDEWEB)

    Lane, Taylor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Parma, Edward J. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    Delayed fission gamma-rays play an important role in determining the time dependent ioniz- ing dose for experiments in the central irradiation cavity of the Annular Core Research Reactor (ACRR). Delayed gamma-rays are produced from both fission product decay and from acti- vation of materials in the core, such as cladding and support structures. Knowing both the delayed gamma-ray emission rate and the time-dependent gamma-ray energy spectrum is nec- essary in order to properly determine the dose contributions from delayed fission gamma-rays. This information is especially important when attempting to deconvolute the time-dependent neutron, prompt gamma-ray, and delayed gamma-ray contribution to the response of a diamond photo-conducting diode (PCD) or fission chamber in time frames of milliseconds to seconds following a reactor pulse. This work focused on investigating delayed gamma-ray character- istics produced from fission products from thermal, fast, and high energy fission of Th-232, U-233, U-235, U-238, and Pu-239. This work uses a modified version of CINDER2008, a transmutation code developed at Los Alamos National Laboratory, to model time and energy dependent photon characteristics due to fission. This modified code adds the capability to track photon-induced transmutations, photo-fission, and the subsequent radiation caused by fission products due to photo-fission. The data is compared against previous work done with SNL- modified CINDER2008 [ 1 ] and experimental data [ 2 , 3 ] and other published literature, includ- ing ENDF/B-VII.1 [ 4 ]. The ability to produce a high-fidelity (7,428 group) energy-dependent photon fluence at various times post-fission can improve the delayed photon characterization for radiation effects tests at research reactors, as well as other applications.

  1. PTCA (1H-pyrrole-2,3,5-tricarboxylic acid) as a marker for oxidative hair treatment.

    Science.gov (United States)

    Petzel-Witt, Silvana; Meier, Sylvia I; Schubert-Zsilavecz, Manfred; Toennes, Stefan W

    2017-09-20

    Hair analysis for the assessment of alcohol or drug abstinence became a routine procedure in forensic toxicology. Hair coloration leading to loss of incorporated xenobiotics and to false negative results turned out to be a major problem. Currently only colored extracts provide hints of manipulations but not bleaching. A liquid chromatographic-mass spectrometric (LC-MSMS) method was developed and validated to determine 1H-pyrrole-2,3,5-tricarboxylic acid (PTCA), a major oxidation product of melanin. PTCA was determined in natural hair samples (n=21) after treatment with 3% hydrogen peroxide (H2 O2 ) for 30 or 40 min with concentrations up to 12% for 40 min. In another series, 12 natural hair samples were submitted to different coloration procedures (henna, tinting, semi-permanent and permanent dyeing, bleaching) and the changes in PTCA content were determined. A significant increase in the PTCA content was found for both incubation times and increasing H2 O2 concentrations. Coloration with henna or tinting had no influence on PTCA levels detected, but a significant increase was observed after semi-permanent and permanent dyeing and bleaching. As PTCA concentrations in natural hair were found to be in a range of hair. In case of naturally low melanin content (lightblond or white hair), no marked increase in PTCA may occur. The present study demonstrated that PTCA is formed during oxidative treatment of melanin in hair, which can be used to detect previous hair coloration including oxidation. This article is protected by copyright. All rights reserved.

  2. Prediction of ground vibration due to the collapse of a 235 m high cooling tower under accidental loads

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Feng; Li, Yi [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Gu, Xianglin, E-mail: gxl@tongji.edu.cn [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Zhao, Xinyuan [Department of Building Engineering, Tongji University, No. 1239 Siping Road, Shanghai 200092 (China); Tang, Dongsheng [Guangdong Electric Power Design Institute, No. 1 Tianfeng Road, Guangzhou, Guangdong 510663 (China)

    2013-05-15

    Highlights: ► Ground vibration due to the collapse of a huge cooling tower was predicted. ► Accidental loads with different characteristics caused different collapse modes. ► Effect of ground vibration on the nuclear-related facilities cannot be ignored. -- Abstract: A comprehensive approach is presented in this study for the prediction of the ground vibration due to the collapse of a 235 m high cooling tower, which can be caused by various accidental loads, e.g., explosion or strong wind. The predicted ground motion is to be used in the safety evaluation of nuclear-related facilities adjacent to the cooling tower, as well as the plant planning of a nuclear power station to be constructed in China. Firstly, falling weight tests were conducted at a construction site using the dynamic compaction method. The ground vibrations were measured in the form of acceleration time history. A finite element method based “falling weight-soil” model was then developed and verified by field test results. Meanwhile, the simulated collapse processes of the cooling tower under two accidental loads were completed in a parallel study, the results of which are briefly introduced in this paper. Furthermore, based on the “falling weight-soil” model, “cooling tower-soil” models were developed for the prediction of the ground vibrations induced by two collapse modes of the cooling tower. Finally, for a deep understanding of the vibration characteristics, a parametric study was also conducted with consideration of different collapse profiles, soil geologies as well as the arrangements of an isolation trench. It was found that severe ground vibration occurred in the vicinity of the cooling tower when the collapse happened. However, the vibration attenuated rapidly with the increase in distance from the cooling tower. Moreover, the “collapse in integrity” mode and the rock foundation contributed to exciting intense ground vibration. By appropriately arranging an isolation

  3. Searches for T-odd correlations in the emission of prompt neutrons in the polarized-neutron-induced fission of 235U nuclei

    Science.gov (United States)

    Danilyan, G. V.; Klenke, J.; Krakhotin, V. A.; Novitsky, V. V.; Pavlov, V. S.; Shatalov, P. B.

    2010-07-01

    The results of an experiment aimed at searches for formally T-odd correlations in the angular distribution of prompt neutrons from the fission of 235U nuclei are presented. The experiment was performed in the MEPHISTO polarized cold-neutron beam from the Munich FRMII reactor. The correlation coefficient proved to be (-3.5 ± 3.4) × 10-5 for a three-vector correlation (TRI effect) and (-5.0 ± 3.4) × 10-5 for a five-vector correlation (ROT effect). This means that no significant effects were discovered within the measurement errors. A comparison with the analogous effects in the ternary fission of 235U nuclei was performed. The values of the corresponding correlations in the angular distribution of prompt fission gamma rays were refined.

  4. Q235钢表面氟硅改性丙烯酸酯乳胶涂层的防腐蚀性能

    Institute of Scientific and Technical Information of China (English)

    李玉峰; 孙皓; 祝晶晶; 高晓辉

    2016-01-01

    为了提高丙烯酸酯乳胶涂层对Q235钢的防腐蚀性能,以甲基丙烯酸甲酯(MMA)、丙烯酸丁酯(BA)为主要单体,甲基丙烯酸十二氟庚酯(DFMA)和乙烯基三甲氧基硅烷(VTMS)作为改性单体,通过乳液聚合方法合成含氟硅丙烯酸酯(氟硅丙)乳液.利用红外光谱(FT-IR)对氟硅丙聚合物的结构进行了表征.在Q235钢表面制备乳胶涂层,测试了氟硅丙乳胶涂层的耐水性和附着力;同时利用电化学测试和盐雾试验研究了涂层对Q235钢的防腐蚀性能.结果表明:氟硅丙乳胶涂层具有较好的耐水性、附着力和防腐蚀性能,其与水的接触角可达到112.3°,吸水率仅为3.0%,附着力为0级,在3.5%NaCl溶液中的电化学阻抗值达到了1×1010 Ω,腐蚀电流密度仅为5.14×10-11A/cm2,对Q235钢具有良好的保护作用.

  5. Novel PI3K and mTOR Inhibitor NVP-BEZ235 Radiosensitizes Breast Cancer Cell Lines under Normoxic and Hypoxic Conditions

    OpenAIRE

    Sebastian Kuger; Emre Cörek; Bülent Polat; Ulrike Kämmerer; Michael Flentje; Djuzenova, Cholpon S.

    2014-01-01

    In the present study, we assessed, if the novel dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor NVP-BEZ235 radiosensitizes triple negative (TN) MDA-MB-231 and estrogen receptor (ER) positive MCF-7 cells to ionizing radiation under various oxygen conditions, simulating different microenvironments as occurring in the majority of breast cancers (BCs). Irradiation (IR) of BC cells cultivated in hypoxic conditions revealed increased radioresistance compared...

  6. The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase.

    OpenAIRE

    Fitzgerald, M. M.; Trester, M. L.; Jensen, G M; McRee, D. E.; Goodin, D B

    1995-01-01

    The activated state of cytochrome c peroxidase, compound ES, contains a cation radical on the Trp-191 side chain. We recently reported that replacing this tryptophan with glycine creates a buried cavity at the active site that contains ordered solvent and that will specifically bind substituted imidazoles in their protonated cationic forms (Fitzgerald MM, Churchill MJ, McRee DE, Goodin DB, 1994, Biochemistry 33:3807-3818). Proposals that a nearby carboxylate, Asp-235, and competing monovalent...

  7. 2,3,5-Trisubstituted pyridines as selective AKT inhibitors-Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity.

    Science.gov (United States)

    Lin, Hong; Yamashita, Dennis S; Zeng, Jin; Xie, Ren; Wang, Wenyong; Nidarmarthy, Sirishkumar; Luengo, Juan I; Rhodes, Nelson; Knick, Victoria B; Choudhry, Anthony E; Lai, Zhihong; Minthorn, Elisabeth A; Strum, Susan L; Wood, Edgar R; Elkins, Patricia A; Concha, Nestor O; Heerding, Dirk A

    2010-01-15

    2,3,5-Trisubstituted pyridines have been designed as potent AKT inhibitors that are selective against ROCK1 based on the comparison between AKT and ROCK1 structures. Substitution at the 2-position of the core pyridine is the key element to provide selectivity against ROCK1. An X-ray co-crystal structure of 9p in PKA supports the proposed rationale of ROCK1 selectivity.

  8. High accuracy measurement of the $^{235}$U(n,f) reaction cross-section in the 10-30 keV neutron energy range

    CERN Multimedia

    The analysis of the neutron flux of n_TOF (in EAR1) revealed an anomaly in the 10-30 keV neutron energy range. While the flux extracted on the basis of the $^{6}$Li(n,t)$^{4}$He and $^{10}$B(n,$\\alpha$)$^{7}$Li reactions mostly agreed with each other and with the results of FLUKA simulations of the neutron beam, the one based on the $^{235}$U(n,f) reaction was found to be systematically lower, independently of the detection system used. A possible explanation is that the $^{235}$U(n,f) crosssection in that energy region, where in principle should be known with an uncertainty of 1%, may be systematically overestimated. Such a finding, which has a negligible influence on thermal reactors, would be important for future fast critical or subcritical reactors. Furthermore, its interest is more general, since the $^{235}$U(n,f) reaction is often used at that energy to determine the neutron flux, or as reference in measurements of fission cross section of other actinides. We propose to perform a high-accuracy, high-r...

  9. Hap2-3-5-Gln3 determine transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions in the yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Hernández, Hugo; Aranda, Cristina; López, Geovani; Riego, Lina; González, Alicia

    2011-03-01

    The transcriptional activation response relies on a repertoire of transcriptional activators, which decipher regulatory information through their specific binding to cognate sequences, and their capacity to selectively recruit the components that constitute a given transcriptional complex. We have addressed the possibility of achieving novel transcriptional responses by the construction of a new transcriptional regulator--the Hap2-3-5-Gln3 hybrid modulator--harbouring the HAP complex polypeptides that constitute the DNA-binding domain (Hap2-3-5) and the Gln3 activation domain, which usually act in an uncombined fashion. The results presented in this paper show that transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions is achieved through the action of the novel Hap2-3-5-Gln3 transcriptional regulator. We propose that the combination of the Hap DNA-binding and Gln3 activation domains results in a hybrid modulator that elicits a novel transcriptional response not evoked when these modulators act independently.

  10. Standard test method for analysis of urine for uranium-235 and uranium-238 isotopes by inductively coupled plasma-mass spectrometry

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This test method covers the determination of the concentration of uranium-235 and uranium-238 in urine using Inductively Coupled Plasma-Mass Spectrometry. This test method can be used to support uranium facility bioassay programs. 1.2 This method detection limits for 235U and 238U are 6 ng/L. To meet the requirements of ANSI N13.30, the minimum detectable activity (MDA) of each radionuclide measured must be at least 0.1 pCi/L (0.0037 Bq/L). The MDA translates to 47 ng/L for 235U and 300 ng/L for 238U. Uranium– 234 cannot be determined at the MDA with this test method because of its low mass concentration level equivalent to 0.1 pCi/L. 1.3 The digestion and anion separation of urine may not be necessary when uranium concentrations of more than 100 ng/L are present. 1.4 Units—The values stated in picoCurie per liter units are to be regarded as standard. The values given in parentheses are mathematical conversions to SI units that are provided for information only and are not considered standard. 1....

  11. Feasibility study of 235U and 239Pu characterization in radioactive waste drums using neutron-induced fission delayed gamma rays

    Science.gov (United States)

    Nicol, T.; Pérot, B.; Carasco, C.; Brackx, E.; Mariani, A.; Passard, C.; Mauerhofer, E.; Collot, J.

    2016-10-01

    This paper reports a feasibility study of 235U and 239Pu characterization in 225 L bituminized waste drums or 200 L concrete waste drums, by detecting delayed fission gamma rays between the pulses of a deuterium-tritium neutron generator. The delayed gamma yields were first measured with bare samples of 235U and 239Pu in REGAIN, a facility dedicated to the assay of 118 L waste drums by Prompt Gamma Neutron Activation Analysis (PGNAA) at CEA Cadarache, France. Detectability in the waste drums is then assessed using the MCNPX model of MEDINA (Multi Element Detection based on Instrumental Neutron Activation), another PGNAA cell dedicated to 200 L drums at FZJ, Germany. For the bituminized waste drum, performances are severely hampered by the high gamma background due to 137Cs, which requires the use of collimator and shield to avoid electronics saturation, these elements being very penalizing for the detection of the weak delayed gamma signal. However, for lower activity concrete drums, detection limits range from 10 to 290 g of 235U or 239Pu, depending on the delayed gamma rays of interest. These detection limits have been determined by using MCNPX to calculate the delayed gamma useful signal, and by measuring the experimental gamma background in MEDINA with a 200 L concrete drum mock-up. The performances could be significantly improved by using a higher interrogating neutron emission and an optimized experimental setup, which would allow characterizing nuclear materials in a wide range of low and medium activity waste packages.

  12. Q235与Zn-Al涂层的耐蚀性及退化过程研究%Study on corrosion resistance and degradation processes of Q 235 and Zn-Al coatings

    Institute of Scientific and Technical Information of China (English)

    王毅; 任玉珊; 雷凯; 魏述和

    2014-01-01

    既有水工钢闸门的主要防腐方法是在钢基体上热喷涂金属涂层,本试验针对Q 235裸钢、Z n -15%Al热喷涂涂层在3.5% NaCl溶液中的腐蚀行为进行对比研究,并分析各自的腐蚀机理。结果表明:裸钢的腐蚀产物(FeOO H和Fe3 O4)随浸泡时间的增加而增厚;Zn-15% Al涂层的腐蚀产物(锌和铝的氧化物及氢氧化物)具有自封闭性,保护基体,减缓腐蚀。裸钢与Zn-Al涂层在快速腐蚀试验中的腐蚀退化过程均呈非线性规律,与自然环境下钢闸门构件锈蚀退化过程相符。%T he main anticorrosive method of existing on hydraulic steel gates is thermal spray metal coat‐ings .In this experiment ,the corrosion behaviors of the bare steel and the Zn‐15% Al thermal spray coating in 3 .5% NaCl solution are investigated ,each corrosion mechanism is analyzed .The results show that the corrosion products (FeOOH and Fe3 O4 ) of the bare steel increases with the increasing of the immersion time .The corrosion products (oxides and hydroxides of zinc and aluminum ) of the Zn‐15% Al coating has a self‐closing property to protect the substrate and reduce corrosion .The corrosion degradation processes of the bare steel and Zn‐Al coating in fast corrosion test show nonlinear law ,which matches with the corro‐sion degradation process of the steel gate components in the natural environment .

  13. Influence of Temperature on Q235 Carbon Steel Deformation Strain-induced Phase Transformation Process of Organizational Change%形变温度对Q235碳素钢应变诱导相变过程组织变化的影响

    Institute of Scientific and Technical Information of China (English)

    吴荷娟

    2015-01-01

    在热模拟单向压缩条件下,分析了形变温度对Q235碳素钢应变诱导相变过程组织变化的影响。结果表明,在大应变下,Q235碳素钢不存在单纯的形变奥氏体状态,其组织变化规律为奥氏体动态结晶、奥氏体动态结晶和铁素体诱导析出、铁素体析出、铁素体动态结晶。碳素钢热加工过程的实质是动态复合转变。%In the thermal simulation unidirectional compression conditions, the influence of deformation temperature on Q235 carbon steel strain-induced phase transformation process of organizational change. The results show that, under the strain, Q235 carbon steel does not exist simply deformed austenitic state, the variation of austenite dynamic recrystallization, austenite and ferrite dynamic crystallization induced precipitation, ferrite precipitation ferrite dynamic crystallization. Essence carbon steel thermal processing is dynamic complex change.

  14. Chemical Stability of P507-N235 System and Its Synergistic Extraction for NdCl3%P507与N235混合溶剂的稳定性及对NdCl3的协萃效应

    Institute of Scientific and Technical Information of China (English)

    杨幼明; 蓝桥发; 邓声华; 聂华平; 叶信宇

    2013-01-01

    The salty waste water generated by saponification in the rare earth extraction process has greatly given rise to environmental pollution.A double solvent system of P507 and N235,which extract rare earth ions and acids respectively,was designed for rare earth extraction without saponification.The chemical stability and synergistic effect of P507-N235 system for Nd3 +were investigated and the experimental results showed that chemical structure of the mixed extractants was stable after extraction-regeneration process although mixing of P507 and N235 was an exothermic reaction with changing characteristic peaks in their infrared spectra.A significant synergistic effect was achieved and the as-prepared complex in extraction was REA3·(R3N·HA)·3R3NHCl.The results obtained may contribute to the development of non-saponification rare earth extraction process.%稀土萃取分离过程皂化产生的含盐废水严重污染环境.利用P507萃取稀土离子、N235萃取酸的特性,设计了P507-N235双溶剂无皂化稀土萃取体系,研究了双溶剂有机相的稳定性及对Nd3+的协萃效应.P507与N235混合时发生放热现象,红外光谱分析显示其特征峰发生了变化,但32次萃取-再生后的混合萃取剂的化学结构稳定;P507与N235对Nd3+具有显著的协萃效果,形成的萃合物为REA3·(R3N·HA)·3R3 NHCl.研究结果为无皂化稀土萃取分离新工艺开发提供了依据.

  15. 235例肺外结核性创面患者流行病学调查%Epidemiological investigation of 235 patients with extra-pulmonary tuberculosis wounds

    Institute of Scientific and Technical Information of China (English)

    常娜; 贾赤宇; 刘真; 张亚洁; 李文婷; 田甜

    2015-01-01

    目的 初步探讨肺外结核性创面流行病学特点和规律,为临床研究提供可靠数据.方法 对笔者单位2010年1月-2012年12月收治的肺外结核性创面患者的性别、年龄、民族、家庭背景、卡介苗接种情况、原发病灶、外伤史这几项资料进行回顾性分析,总结其规律及特点. 结果 5 863例肺外结核病患者中,235例出现结核性创面,占4.0%.其中男139例、女96例,男女之比为1.4∶1.0.年龄1~87(37±18)岁,其中大于15岁且小于或等于30岁青壮年患者构成比最大(100例,42.6%).多数患者为汉族;仅有11例患者为少数民族,占4.7%.患者中163例来自农村,占69.4%;72例来自城镇,占30.6%.卡介苗接种率为13.6%(32例).原发病灶中,以周围淋巴结结核为主,共112例,占47.7%,其中又以颈部淋巴结结核为主(99例,88.4%).21例(男19例、女2例)患者近期有车祸等外伤史. 结论 结核性创面有一定的发病率,并非罕见,以农村地区青壮年人群多发,患者的卡介苗接种率较低,颈部淋巴结结核为主要原发病灶.%Objective To investigate the epidemiological characteristics and patterns of extra-pulmonary tuberculosis wounds in order to provide reliable data for further clinical research.Methods Records of patients with extra-pulmonary tuberculosis wounds hospitalized from January 2010 to December 2012 were retrospectively analyzed,including gender,age,nationality,family background,Bacille CalmetteGuerin (BCG) vaccination,primary lesion,and history of injury.Results Tuberculosis wounds were found in 235 patients among 5 863 patients with extra-pulmonary tuberculosis,accounting for 4.0%.Among the patients with tuberculosis wounds,there were 139 male and 96 female,and the ratio of male to female was 1.4∶ 1.0.The age of patients ranged from 1 to 87 (37 ± 18) years old,and the highest incidence occurred in patients older than 15 and younger than or equal to 30 years old (100 cases

  16. 235例芦山地震伤员静脉血栓的筛查与防治%Screening, Prevention and Treatment of Venous Thrombosis for 235 Lushan Earthquake Victims

    Institute of Scientific and Technical Information of China (English)

    丁明甫; 廖栩

    2013-01-01

    目的 报告四川大学华西医院芦山地震伤员静脉血栓筛查与防治的情况.方法 采用血管彩色多普勒筛查该院收治的芦山地震伤员,对检出静脉血栓的伤员进行合理治疗;对未发现静脉血栓者进行早期预防.结果 截至震后11天,采用血管彩色多普勒筛查仍在四川大学华西医院住院治疗的235例芦山地震伤员,共检出26例静脉血栓伤员,其中下肢静脉血栓25例,上肢静脉血栓1例.采用单纯康复干预及单纯药物干预各3例,康复干预联合药物干预20例.截至震后30天,26例静脉血栓伤员复查结果显示,11例好转(5例完全再通,6例部分再通).地震伤员进行药物及其他干预,其中只予药物干预的3例伤员有1例静脉血栓完全再通,只予康复干预的3例伤员有1例静脉血栓部分再通,药物联合其他干预措施的20例伤员有4例完全再通,5例部分再通.结论 芦山地震静脉血栓伤员大部分为老年及女性,绝大多数在ICU住院,大部分存在不同程度骨折,及时筛查防治静脉血栓可缓解局部疼痛,促使其早期进入康复治疗,防止肺栓塞等风险发生.对检出静脉血栓者采取康复和/或药物干预,对未检出静脉血栓但存在高危因素者采取康复和/或药物干预,能有效防治血栓进一步形成及血栓脱落带来的不良后果.%Objective To report the screening,prevention and treatment of venous thrombosis for Lushan earthquake victims in the West China Hospital of Sichuan University.Methods Among the Lushan earthquake victims screened by vascular color Doppler,those with detected venous thrombosis were treated reasonably,and those without detected venous thrombosis were prevented early.Results There were total 235 Lushan earthquake victims in the hospital as of the 11th day after earthquake,and they were screened by vascular color Doppler.Among 26 cases with detected venous thrombosis,25 were lower limb venous thrombosis,and the other

  17. Chemical, optical and other data collected aboard the THOMAS G. THOMPSON during cruise TN235 in the South Pacific Ocean from 2009-05-16 to 2009-06-08 (NODC Accession 0104352)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104352 includes chemical, optical and other data collected aboard the THOMAS G. THOMPSON during cruise TN235 in the South Pacific Ocean from...

  18. 变电构架中Q235~Q420牌号角钢和钢管适用性分析%Applicability analysis of Q235 ~ Q420 angle steels and steel pipes in substation frame

    Institute of Scientific and Technical Information of China (English)

    万红; 彭奕亮; 李洪波; 杨光; 韩选民; 徐茂行

    2011-01-01

    为研究不同牌号角钢和钢管在变电构架中的适用范围,应用有关规范对Q235~Q420轴心受压角钢和钢管、单向偏心受压钢管以及纯弯钢管的承载力比值进行了大量计算分析.结果表明:相对于一般规格轴心受压Q235角钢和钢管,Q345,Q390,Q420钢材的长细比经济适用范围分别为λ≤100,λ≤110和λ≤120;相对于一般规格轴心受压Q345角钢和钢管,Q390和Q420钢材的长细比经济适用范围分别为λ≤40和λ≤70;高强钢应用于单向压弯钢管和纯弯钢管时,其经济性能将得以充分发挥.%To study the applicability of Q235 ~ Q420 angle steels and steel pipes in substation frame, the load carrying capacity ratio of Q235 - Q420 axial compressive angle steels and steel pipes, eccentrically loaded and pure bending steel pipes were analyzed according to some relevant standards. Four kinds of steels have been considered: Q235, Q345, Q390, Q420. The results show that relative to general Q235 axial compressive angle steels and steel pipes,economic application scope of slenderness ratio for Q345 ,Q390 and Q420 steel are λ≤ 100, λ≤ 110 andλ≤ 120 respectively. Relative to general Q345 axial compressive angle steels and steel pipes, economic application scope of slenderness ratio for Q390 and Q420 are λ≤40 and λ≤ 70 respectively. Good economic results will be obtained for high strength steels used in eccentrically loaded and pure bending steel pipes.

  19. Involvement of IGF-1 receptor signaling pathway in the neuroprotective effects of Icaritin against MPP(+)-induced toxicity in MES23.5 cells.

    Science.gov (United States)

    Jiang, Ming-Chun; Chen, Xiao-Han; Zhao, Xia; Zhang, Xue-Jie; Chen, Wen-Fang

    2016-09-01

    Icaritin, a natural derivative of Icariin, is the major bioactive component of Epimedium Genus. The present study tested the hypothesis that the neuroprotective effects of Icaritin against 1-Methyl-4-phenylpyridinium ion (MPP(+))-induced toxicity involved activation of the insulin-like growth factor-1 receptor (IGF-1R) signaling pathway in MES23.5 cells. Our results revealed that Icaritin pretreatment attenuated the MPP(+)-induced decrease of cell viability in a dose-dependent fashion. Co-pretreatment with phosphatidylinositol 3-kinase (PI3-K) inhibitor LY294002, mitogen-activated protein kinase (MEK) inhibitor PD98059 or IGF-1 receptor antagonist JB-1 could completely block the protective effects of Icaritin. Moreover, Icaritin pretreatment down-regulated MPP(+)-induced increase of Bax/Bcl-2 ratio transcriptionally and post-transcriptionally. Further study revealed that Icaritin pretreatment could restore the decreased protein expression of Akt and extracellular signal-regulated kinase 1/2 (ERK1/2) induced by MPP(+) and these effects could be completely abolished by LY294002, PD98059 or JB-1. Additionally, Icaritin treatment alone time-dependently enhanced the phosphorylation of Akt and ERK1/2 in MES23.5 cells. The activation of Akt and ERK1/2 by Icaritin could be completely blocked by JB-1, LY294002 or PD98059. Taken together, our data demonstrate that IGF-1 receptor mediated activation of PI3K/Akt and MEK/ERK1/2 signaling pathways are involved in the protective effects of Icaritin against MPP(+)-induced toxicity in MES23.5 cells.

  20. Exploratory study of fission product yields of neutron-induced fission of 235U , 238U , and 239Pu at 8.9 MeV

    Science.gov (United States)

    Bhatia, C.; Fallin, B. F.; Gooden, M. E.; Howell, C. R.; Kelley, J. H.; Tornow, W.; Arnold, C. W.; Bond, E.; Bredeweg, T. A.; Fowler, M. M.; Moody, W.; Rundberg, R. S.; Rusev, G. Y.; Vieira, D. J.; Wilhelmy, J. B.; Becker, J. A.; Macri, R.; Ryan, C.; Sheets, S. A.; Stoyer, M. A.; Tonchev, A. P.

    2015-06-01

    Using dual-fission chambers each loaded with a thick (200 -400 -mg /c m2) actinide target of 235 ,238U or 239Pu and two thin (˜10 -100 -μ g /c m2) reference foils of the same actinide, the cumulative yields of fission products ranging from 92Sr to 147Nd have been measured at En= 8.9 MeV . The 2H(d ,n ) 3He reaction provided the quasimonoenergetic neutron beam. The experimental setup and methods used to determine the fission product yield (FPY) are described, and results for typically eight high-yield fission products are presented. Our FPYs for 235U(n ,f ) , 238U(n ,f ) , and 239Pu(n ,f ) at 8.9 MeV are compared with the existing data below 8 MeV from Glendenin et al. [Phys. Rev. C 24, 2600 (1981), 10.1103/PhysRevC.24.2600], Nagy et al. [Phys. Rev. C 17, 163 (1978), 10.1103/PhysRevC.17.163], Gindler et al. [Phys. Rev. C 27, 2058 (1983), 10.1103/PhysRevC.27.2058], and those of Mac Innes et al. [Nucl. Data Sheets 112, 3135 (2011), 10.1016/j.nds.2011.11.009] and Laurec et al. [Nucl. Data Sheets 111, 2965 (2010), 10.1016/j.nds.2010.11.004] at 14.5 and 14.7 MeV, respectively. This comparison indicates a negative slope for the energy dependence of most fission product yields obtained from 235U and 239Pu , whereas for 238U the slope issue remains unsettled.

  1. Trace element distribution and 235U/238U ratios in Euphrates waters and in soils and tree barks of Dhi Qar province (southern Iraq).

    Science.gov (United States)

    Riccobono, Francesco; Perra, Guido; Pisani, Anastasia; Protano, Giuseppe

    2011-09-01

    To assess the quality of the environment in southern Iraq after the Gulf War II, a geochemical survey was carried out. The survey provided data on the chemistry of Euphrates waters, as well as the trace element contents, U and Pb isotopic composition, and PAH levels in soil and tree bark samples. The trace element concentrations and the (235)U/(238)U ratio values in the Euphrates waters were within the usual natural range, except for the high contents of Sr due to a widespread presence of gypsum in soils of this area. The trace element contents in soils agreed with the common geochemistry of soils from floodplain sediments. Some exceptions were the high contents of Co, Cr and Ni, which had a natural origin related to ophiolitic outcrops in the upper sector of the Euphrates basin. The high concentrations of S and Sr were linked to the abundance of gypsum in soils. A marked geochemical homogeneity of soil samples was suggested by the similar distribution pattern of rare earth elements, while the (235)U/(238)U ratio was also fairly homogeneous and within the natural range. The chemistry of the tree bark samples closely reflected that of the soils, with some notable exceptions. Unlike the soils, some tree bark samples had anomalous values of the (235)U/(238)U ratio due to mixing of depleted uranium (DU) with the natural uranium pool. Moreover, the distribution of some trace elements (such as REEs, Th and Zr) and the isotopic composition of Pb in barks clearly differed from those of the nearby soils. The overall results suggested that significant external inputs occurred implying that once formed the DU-enriched particles could travel over long distances. The polycyclic aromatic hydrocarbon concentrations in tree bark samples showed that phenanthrene, fluoranthene and pyrene were the most abundant components, indicating an important role of automotive traffic.

  2. The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase.

    Science.gov (United States)

    Fitzgerald, M M; Trester, M L; Jensen, G M; McRee, D E; Goodin, D B

    1995-09-01

    The activated state of cytochrome c peroxidase, compound ES, contains a cation radical on the Trp-191 side chain. We recently reported that replacing this tryptophan with glycine creates a buried cavity at the active site that contains ordered solvent and that will specifically bind substituted imidazoles in their protonated cationic forms (Fitzgerald MM, Churchill MJ, McRee DE, Goodin DB, 1994, Biochemistry 33:3807-3818). Proposals that a nearby carboxylate, Asp-235, and competing monovalent cations should modulate the affinity of the W191G cavity for ligand binding are addressed in this study. Competitive binding titrations of the imidazolium ion to W191G as a function of [K+] show that potassium competes weakly with the binding of imidazoles. The dissociation constant observed for potassium binding (18 mM) is more than 3,000-fold higher than that for 1,2-dimethylimidazole (5.5 microM) in the absence of competing cations. Significantly, the W191G-D235N double mutant shows no evidence for binding imidazoles in their cationic or neutral forms, even though the structure of the cavity remains largely unperturbed by replacement of the carboxylate. Refined crystallographic B-values of solvent positions indicate that the weakly bound potassium in W191G is significantly depopulated in the double mutant. These results demonstrate that the buried negative charge of Asp-235 is an essential feature of the cation binding determinant and indicate that this carboxylate plays a critical role in stabilizing the formation of the Trp-191 radical cation.

  3. Association between RAS Gene Polymorphisms (ACE I/D, AGT M235T and Henoch-Schönlein Purpura in a Turkish Population

    Directory of Open Access Journals (Sweden)

    Sinem Nalbantoglu

    2013-01-01

    Full Text Available Henoch-Schönlein purpura (HSP is a small-vessel vasculitis of autoimmune hypersensitivity, and renin-angiotensin system (RAS regulates vascular homeostasis and inflammation with activation of cytokine release. Thus, we aimed to investigate the association between HSP and ACE I/D and AGT M235T polymorphisms. Genotyping was determined by allele specific PCR and PCR-RFLP. We obtained a significant difference in genotype distribution (p = 0.003 and allele frequencies (p 0.05 and allele frequencies (p > 0.05 of the AGT M235T polymorphism. Risk assessment showed significant risk for HSP in the subjects both with the ID + DD genotype (p = 0.019, OR: 2.288, 95% CI: 1.136–4.609 and D allele (OR: D vs. I: 2.0528, 95% CI: 1.3632–3.0912, p = 0.001 while no significant risk was obtained for HSP in the subjects both with the MT + TT genotype (p = 0.312, OR: 1.3905, 95% CI: 0.7326–2.6391 and T allele (OR: T vs. M: 1.065, 95% CI: 0.729–1.557, p = 0.743. Furthermore, when patients were stratified by the presence of certain systemic complications of HSP, no significant association was detected with ACE I/D, and AGT M235T polymorphisms. Our findings suggest that ACE I/D polymorphism is significantly associated with HSP susceptibility.

  4. Feasibility study of {sup 235}U and {sup 239}Pu characterization in radioactive waste drums using neutron-induced fission delayed gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Nicol, T. [CEA, DEN, Cadarache, Nuclear Measurement Laboratory, F-13108 Saint-Paul-lez-Durance (France); FZJ, Institute of Energy and Climate Research – Nuclear Waste Management and Reactor Safety, Wilhelm-Johnen-Straße, d-52425 Jülich (Germany); Pérot, B., E-mail: bertrand.perot@cea.fr [CEA, DEN, Cadarache, Nuclear Measurement Laboratory, F-13108 Saint-Paul-lez-Durance (France); Carasco, C. [CEA, DEN, Cadarache, Nuclear Measurement Laboratory, F-13108 Saint-Paul-lez-Durance (France); Brackx, E. [CEA, DEN, Marcoule, Metallography and Chemical Analysis Laboratory, F-30207 Bagnols-sur-Cèze (France); Mariani, A.; Passard, C. [CEA, DEN, Cadarache, Nuclear Measurement Laboratory, F-13108 Saint-Paul-lez-Durance (France); Mauerhofer, E. [FZJ, Institute of Energy and Climate Research – Nuclear Waste Management and Reactor Safety, Wilhelm-Johnen-Straße, d-52425 Jülich (Germany); Collot, J. [Laboratoire de Physique Subatomique et de Cosmologie, Université Grenoble Alpes, CNRS/IN2P3 Grenoble (France)

    2016-10-01

    This paper reports a feasibility study of {sup 235}U and {sup 239}Pu characterization in 225 L bituminized waste drums or 200 L concrete waste drums, by detecting delayed fission gamma rays between the pulses of a deuterium-tritium neutron generator. The delayed gamma yields were first measured with bare samples of {sup 235}U and {sup 239}Pu in REGAIN, a facility dedicated to the assay of 118 L waste drums by Prompt Gamma Neutron Activation Analysis (PGNAA) at CEA Cadarache, France. Detectability in the waste drums is then assessed using the MCNPX model of MEDINA (Multi Element Detection based on Instrumental Neutron Activation), another PGNAA cell dedicated to 200 L drums at FZJ, Germany. For the bituminized waste drum, performances are severely hampered by the high gamma background due to {sup 137}Cs, which requires the use of collimator and shield to avoid electronics saturation, these elements being very penalizing for the detection of the weak delayed gamma signal. However, for lower activity concrete drums, detection limits range from 10 to 290 g of {sup 235}U or {sup 239}Pu, depending on the delayed gamma rays of interest. These detection limits have been determined by using MCNPX to calculate the delayed gamma useful signal, and by measuring the experimental gamma background in MEDINA with a 200 L concrete drum mock-up. The performances could be significantly improved by using a higher interrogating neutron emission and an optimized experimental setup, which would allow characterizing nuclear materials in a wide range of low and medium activity waste packages.

  5. Calculation of K{sub {infinity}} for homogeneous {sup 235}U metal mixtures: Will the real K{sub {infinity}} please stand up?

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, W.C.; Petrie, L.M.; Wright, R.Q.; Parks, C.V. [Oak Ridge National Lab., TN (United States)

    1997-06-01

    This paper very briefly analyzes a journal article about calculating k{sub {infinity}} for metals mixed with uranium 235, and compares the article results with other calculation methods. The article suggested that continuous energy cross sections gave more accurate results than groupwise cross sections. The mixtures described in the article were dry, fast systems with several unusual characteristics; however, the majority of multigroup libraries used for analysis were developed for well moderated thermal systems. The results of calculations performed using several different codes and cross sections for three uranium/metal mixtures are presented in this paper. 1 tab.

  6. Evaluation of fission cross sections and covariances for {sup 233}U, {sup 235}U, {sup 238}U, {sup 239}Pu, {sup 240}Pu, and {sup 241}Pu

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko [Kyushu Univ., Fukuoka (Japan); Matsunobu, Hiroyuki [Data Engineering, Inc. (Japan); Murata, Toru [AITEL Corporation, Tokyo (JP)] [and others

    2000-02-01

    A simultaneous evaluation code SOK (Simultaneous evaluation on KALMAN) has been developed, which is a least-squares fitting program to absolute and relative measurements. The SOK code was employed to evaluate the fission cross sections of {sup 233}U, {sup 235}U, {sup 238}U, {sup 239}Pu, {sup 240}Pu, and {sup 241}Pu for the evaluated nuclear data library JENDL-3.3. Procedures of the simultaneous evaluation and the experimental database of the fission cross sections are described. The fission cross sections obtained were compared with evaluated values given in JENDL-3.2 and ENDF/B-VI. (author)

  7. Electrolyte properties of 1-alkyl-2,3,5-trimethylpyrazolium cation-based room-temperature ionic liquids for lithium secondary batteries

    Energy Technology Data Exchange (ETDEWEB)

    Seki, Shiro; Kobayashi, Takeshi; Serizawa, Nobuyuki; Kobayashi, Yo; Takei, Katsuhito; Miyashiro, Hajime [Materials Science Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI), 2-11-1, Iwado-kita, Komae, Tokyo 201-8511 (Japan); Hayamizu, Kikuko; Tsuzuki, Seiji [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Center 5, Tsukuba, Ibaraki 305-8565 (Japan); Mitsugi, Takushi; Umebayashi, Yasuhiro [Department of Chemistry, Faculty of Science, Kyushu University, Hakozaki, Higashi-ku, Fukuoka 812-8581 (Japan); Watanabe, Masayoshi [Department of Chemistry and Biotechnology, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa (Japan)

    2010-09-15

    The physicochemical and electrochemical properties of three 1-alkyl-2,3,5-trimethylpyrazolium cation-based room-temperature ionic liquids with various alkyl chain lengths were investigated. The temperature dependences of density, viscosity, and ionic conductivity were obtained by precise measurements. Electrolyte properties of these room-temperature ionic liquids were also examined from the viewpoint of their uses in lithium secondary batteries ([LiCoO{sub 2} positive electrode vertical stroke electrolyte vertical stroke lithium metal negative electrode]). It was found that the alkyl chain length affects the charge-discharge performances of cells. (author)

  8. Venus mit Waffen. Die Darstellungen und die Rolle der Göttin in der Münzpropaganda der Zeit der Soldatenkaiser (235–284 n. Chr.

    Directory of Open Access Journals (Sweden)

    Ferenc Barna

    2015-02-01

    Full Text Available There are many representational types of Venus in the coinage of the soldier emperors’ era (235–284/285. The goddess is depicted with various attributes, often with apple, sceptre, or with Cupid, however, in some cases she is with weapons (for example with helmet, shields, or even with spear or with triumphal attributes (palm-branch, Victory, which coins surprisingly describe the goddess of love in connection with very unusual phenomena: military and victory. The present paper deals with the variety of these coin types in the above mentioned period and focuses on their tradition in the coinage of the principate, especially in the Severan era.

  9. Comparison of the (p,xn) cross sections from /sup 238/U, /sup 235/U, and /sup 232/Th targets irradiated with 200-MeV protons

    Energy Technology Data Exchange (ETDEWEB)

    Chu, Y.Y.; Zhou, M.L.

    1982-01-01

    We have measured absolute cross sections for (p,xn) reactions (x ranges from 0 to 8) from /sup 238/U, /sup 235/U, and /sup 232/Th targets irradiated with 200-MeV protons at the Brookhaven AGS Linac injector. Chemical yields were determined by using /sup 239/Np and /sup 233/Pa as tracers. Yield patterns obtained in this work can be compared to the experimental results and theoretical calculations from earlier work, and they are consistent within the framework of intranuclear cascade followed by neutron evaporation and fission competition.

  10. Accurate measurements of fission-fragment yields in 234,235,236,238U(γ,f with the SOFIA set-up

    Directory of Open Access Journals (Sweden)

    Chatillon A.

    2016-01-01

    Full Text Available SOFIA (Studies On Fission with Aladin is a new experimental set-up dedicated to accurate measurement of fission-fragments isotopic yields. It is located at GSI, the only place to use inverse kinematics at relativistic energies in order to study the (γ,f electromagnetic-induced fission. The SOFIA set-up is a large-acceptance magnetic spectrometer, which allows to fully identify both fission fragments in coincidence on the whole fission-fragment range. This paper will report on fission yields obtained in 234,235,236,238U(γ,f reactions.

  11. Determination of the isotopic ratio {sup 234} U/{sup 238} U and {sup 235} U/{sup 238} U in uranium commercial reagents by alpha spectroscopy; Determinacion de la relacion isotopica {sup 234} U/{sup 238} U y {sup 235} U/{sup 238} U en reactivos comerciales de uranio por espectrometria alfa

    Energy Technology Data Exchange (ETDEWEB)

    Iturbe G, J.L

    1990-02-15

    In this work the determination of the isotope ratio {sup 234} U/{sup 238} U and {sup 235} U/{sup 238} U obtained by means of the alpha spectroscopy technique in uranium reagents of commercial marks is presented. The analyzed uranium reagents were: UO{sub 2} (*) nuclear purity, UO{sub 3} (*) poly-science, metallic uranium, uranyl nitrate and uranyl acetate Merck, uranyl acetate and uranyl nitrate Baker, uranyl nitrate (*) of the Refinement and Conversion Department of the ININ, uranyl acetate (*) Medi-Lab Sigma of Mexico and uranyl nitrate Em Science. The obtained results show that the reagents that are suitable with asterisk (*) are in radioactive balance among the one {sup 234} U/{sup 238} U, since the obtained value went near to the unit. In the case of the isotope ratio {sup 235} U/{sup 238} U the near value was also obtained the one that marks the literature that is to say 0.04347, what indicates that these reagents contain the isotope of {sup 235} U in the percentage found in the nature of 0.71%. The other reagents are in radioactive imbalance among the {sup 234} U/{sup 238} U, the found values fluctuated between 0.4187 and 0.1677, and for the quotient of activities {sup 235} U/{sup 238} U its were of 0.0226, and the lowest of 0.01084. Also in these reagents it was at the {sup 236} U as impurity. The isotope of {sup 236} U is an isotope produced artificially, for what is supposed that the reagents that are in radioactive imbalance were synthesized starting from irradiated fuel. (Author)

  12. Measurements of neutron-induced capture and fission reactions on $^{235}$ U: cross sections and ${\\alpha}$ ratios, photon strength functions and prompt ${\\gamma}$-ray from fission

    CERN Multimedia

    We propose to measure the neutron-induced capture cross section of the fissile isotope $^{235}$U using a fission tagging set-up. This new set-up has been tested successfully in 2010 and combines the n_TOF 4${\\pi}$ Total Absorption Calorimeter (TAC) with MicroMegas (MGAS) fission detectors. It has been proven that such a combination of detectors allows distinguishing with very good reliability the electromagnetic cascades from the capture reactions from dominant ${\\gamma}$-ray background coming from the fission reactions. The accurate discrimination of the fission background is the main challenge in the neutron capture cross section measurements of fissile isotopes. The main results from the measurement will be the associated capture cross section and ${\\alpha}$ ratio in the resolved (0.3-2250 eV) and unresolved (2.25-30 keV) resonance regions. According to the international benchmarks and as it is mentioned in the NEA High Priority Request List (HPRL), the 235U(n,${\\gamma}$) cross section is of utmost impo...

  13. The 235U(n,2n(gamma)) Yrast Partial Gamma-Ray Cross Sections: A Report on the 1998 -- 1999 GEANIE Data and Analysis Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Younes, W; Becker, J A; Bernstein, L A; Garret, P E; McGrath, C A; McNabb, D P; Nelson, R O; Devlin, M; Fotiades, N; Johns, G D

    2000-09-01

    Measurements of partial {sup 235}U(n,2n{gamma}) {gamma}-ray cross sections have been carried out as a function of incident neutron energy using the GEANIE spectrometer at LANSCE/WNR. The yields of {gamma} rays resulting from the population of discrete levels in the residual nucleus {sup 234}U have been measured at incident neutron energies in the 1-20-MeV range. These data provide, with the aid of nuclear reaction modeling, a measurement of the {sup 235}U(n,2n) reaction cross section and serve as a proof of principle of the y-ray technique for the parallel 23gPu(n,2n) measurement [l]. This paper presents the analysis of the {gamma}-ray data and the extraction of partial {gamma}-ray cross sections as a function of incident neutron energy. Uncertainties associated with the spectroscopic analysis of the data and validation of the results are discussed in detail.

  14. Synthesis of imidazoline-based dissymmetric bis-quaternary ammonium gemini surfactant and its inhibition mechanism on Q235 steel in hydrochloric acid medium

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J.; Gong, X.L.; Song, W.W.; Jiang, B.; Du, M. [Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao, Shandong Province (China)

    2012-07-15

    An imidazoline-based dissymmetric bis-quaternary ammonium gemini surfactant has been synthesized. Its surface active properties at equilibrium in water at 25 C were determined. The inhibitive effect of the compound on Q235 steel in 1 M hydrochloric solution was investigated by the weight-loss method, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), scanning electron microscopy (SEM) analysis, and quantum chemical calculations. The results indicate that the compound has high surface properties and the inhibition efficiency (IE) increases with the increase in inhibitor concentration, which attain the maximum value around the CMC value. The imidazoline-based dissymmetric bis-quaternary ammonium acts as a mixed type inhibitor mainly inhibiting the cathodic processes and does not change the mechanism of either hydrogen evolution reaction or mild steel dissolution. The best IE is obtained at the immersion time of 144 h. The adsorption of the studied inhibitor on Q235 steel can be fitted to a Langmuir isotherm and the adsorption process is a spontaneous chemical adsorption. Quantum chemistry calculation results show that the imidazoline ring and heteroatoms of N, O, are the active sites of the inhibitors. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Development of self-interrogation neutron resonance densitometry (SINRD) to measure U-235 and Pu-239 content in a PWR spent fuel assembly

    Energy Technology Data Exchange (ETDEWEB)

    Lafleur, Adrienne M [Los Alamos National Laboratory; Charlton, William S [Los Alamos National Laboratory; Menlove, Howard O [Los Alamos National Laboratory; Swinhoe, Martyn T [Los Alamos National Laboratory

    2009-01-01

    The use of Self-Interrogation Neutron Resonance Densitometry (SINRD) to measure the {sup 235}U and {sup 239}Pu content in a PWR spent fuel assembly was investigated via Monte Carlo N-Particle eXtended transport code (MCNPX) simulations. The sensitivity of SINRD is based on using the same fissile materials in the fission chambers as are present in the fuel because the effect of resonance absorption lines in the transmitted flux is amplified by the corresponding (n, f) reaction peaks in fission chamber. These simulations utilize the {sup 244}Cm spontaneous fission neutrons to self-interrogate the fuel pins. The amount of resonance absorption of these neutrons in the fuel can be measured using {sup 235}U and {sup 239}Pu fission chambers placed adjacent to the assembly. We used ratios of different fission chambers to reduce the sensitivity of the measurements to extraneous material present in fuel. The development of SINRD to measure the fissile content in spent fuel is of great importance to the improvement of nuclear safeguards and material accountability. Future work includes the use of this technique to measure the fissile content in FBR spent fuel and heavy metal product from reprocessing methods.

  16. Thermal-neutron-induced alpha-accompanied fission of /sup 235/U investigation of the low energy part of the alpha spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Caitucoli, F. (CEA Centre d' Etudes Nucleaires de Grenoble, 38 (France). Dept. de Recherche Fondamentale); Leroux, B.; Cajan, N.; Benfoughal, T.; Doan, T.P.; El Hage, F.; Sicre, A. (CEA Centre d' Etudes Nucleaires de Bordeaux-Gradignan, 33 - Gradignan (France)); Asghar, M. (Institut Max von Laue - Paul Langevin, 38 - Grenoble (France)); Barreau, G.; Perrin, P. (Institut Max von Laue - Paul Langevin, 38 - Grenoble (France))

    1980-01-01

    The energy spectrum of the ..cap alpha..-particles emitted in the thermal-neutron induced fission of /sup 235/U was measured from 11.5 MeV down to 2 MeV using the parabola mass spectrometer Lohengrin at the I.L.L. high flux reactor. This low energy part of the energy spectrum presents a smooth connection with the energy spectra which have been recently reported above 7 MeV. The overall energy spectrum, which is known to be quasi-gaussian above 12 MeV, is slightly asymmetric at low energy, where the observed particles are 6% more than expected from a gaussian shape. As a consequence, all the values reported for /sup 235/ U for the rate of ..cap alpha..-accompanied fission compared to binary fission have to be multiplied by 1.06. This asymmetry is about 2 times less important than the one reported for /sup 252/Cf. No evidence was seen for any intense low energy component as reported before. The possible reasons for the existence of this asymmetry are discussed.

  17. Effects of Fission Yield Data in the Calculation of Antineutrino Spectra for 235U (n ,fission) at Thermal and Fast Neutron Energies

    Science.gov (United States)

    Sonzogni, A. A.; McCutchan, E. A.; Johnson, T. D.; Dimitriou, P.

    2016-04-01

    Fission yields form an integral part of the prediction of antineutrino spectra generated by nuclear reactors, but little attention has been paid to the quality and reliability of the data used in current calculations. Following a critical review of the thermal and fast ENDF/B-VII.1 235U 235 fission yields, deficiencies are identified and improved yields are obtained, based on corrections of erroneous yields, consistency between decay and fission yield data, and updated isomeric ratios. These corrected yields are used to calculate antineutrino spectra using the summation method. An anomalous value for the thermal fission yield of 86Ge generates an excess of antineutrinos at 5-7 MeV, a feature which is no longer present when the corrected yields are used. Thermal spectra calculated with two distinct fission yield libraries (corrected ENDF/B and JEFF) differ by up to 6% in the 0-7 MeV energy window, allowing for a basic estimate of the uncertainty involved in the fission yield component of summation calculations. Finally, the fast neutron antineutrino spectrum is calculated, which at the moment can only be obtained with the summation method and may be relevant for short baseline reactor experiments using highly enriched uranium fuel.

  18. Measurements of the effective cumulative fission yields of 143Nd, 145Nd, 146Nd, 148Nd and 150Nd for 235U in the PHENIX fast reactor

    Directory of Open Access Journals (Sweden)

    Privas Edwin

    2016-01-01

    Full Text Available The effective Neodymium cumulative fission yields for 235U have been measured in the fast reactor PHENIX relatively to the 235U fission cross-section. The data were derived from isotope-ratio measurements obtained in the frame of the PROFIL-1, PROFIL-2A and PROFIL-2B programs. The interpretations of the experimental programs were performed with the ERANOS code in association with the Joint Evaluated Fission and Fusion library JEFF-3.1.1. Final results for 143Nd, 145Nd, 146Nd, 148Nd and 150Nd were 5.61%, 3.70%, 2.83%, 1.64% and 0.66%, respectively. The relative uncertainties attached to each of the cumulative fission yields lie between 2.1% and 2.4%. The main source of uncertainty is due to the fluence scaling procedure (<2%. The uncertainties on the Neodymium capture cross-sections provide a contribution lower than 1%. The energy dependence of the fission yields was studied with the GEF code from the thermal energy to 20 MeV. Neutron spectrum average corrections, deduced from GEF calculations, were applied to our effective fission yields with the aim of estimating fission yields at 400 keV and 500 keV, as given in the International Evaluated Nuclear Data Files (JEFF, ENDF/B and JENDL. The neutron spectrum average correction calculated for the PROFIL results remains lower than 1.5%.

  19. Discovery of Infalling Motion with Rotation of the Cluster-forming Clump S235AB and Its Implication to the Clump Structures

    Science.gov (United States)

    Shimoikura, Tomomi; Dobashi, Kazuhito; Matsumoto, Tomoaki; Nakamura, Fumitaka

    2016-12-01

    We report the discovery of infalling motion with the rotation of S235AB, a massive cluster-forming clump (˜ 1× {10}3 {M}⊙ ) in the S235 region. Our C18O observations with the 45 m telescope at the Nobeyama Radio Observatory have revealed an elliptical shape of the clump. A position-velocity diagram taken along its major axis exhibits two well-defined peaks symmetrically located, with respect to the clump center. This is similar to that found for a dynamically infalling envelope with rotation around a single protostar, modeled by N. Ohashi et al., indicating that the cluster-forming clump is also collapsing by the self-gravity toward the clump center. With analogue to Ohashi et al.'s model, we made a simple model of an infalling, rotating clump to fit the observed data. Based on the inferred model parameters, as well as results of earlier observations and simulations in the literature, we discuss the structures of the clump such as the relation among the global mass infall rate (˜ 1× {10}-3 {M}⊙ yr-1), formation of a compact core (with a mass and size of ˜4 {M}⊙ and ≲ 0.1 pc) at the center, and a massive star (˜11 {M}⊙ ) forming in the core.

  20. Discovery of Infalling Motion with Rotation of the Cluster-Forming Clump S235AB and Its Implication to the Clump Structures

    CERN Document Server

    Shimoikura, Tomomi; Matsumoto, Tomoaki; Nakamura, Fumitaka

    2016-01-01

    We report the discovery of infalling motion with rotation of S235AB the massive cluster-forming clump (~10^3 Mo) in the S235 region. Our C18O observations with the 45m telescope at the Nobeyama Radio Observatory have revealed the elliptical shape of the clump. Position-velocity (PV) diagram taken along its major axis exhibits two well-defined peaks symmetrically located with respect to the clump center, which is similar to that found for a dynamically infalling envelope with rotation around a single protostar modeled by N. Ohashi and his collaborators, indicating that the cluster-forming clump is also collapsing by the self-gravity toward the clump center. With analogue to Ohashi's model, we made a simple model of an infalling, rotating clump to fit the observed data. Based on the inferred model parameters as well as results of earlier observations and simulations in the literature, we discuss structures of the clump such as the relation among the global mass infall rate (~10^-3 Mo/yr), formation of a compact...

  1. Field Measurement of Am241 and Total Uranium at a Mixed Oxide Fuel Facility with Variable Uranium Enrichments Ranging from 0.3% to 97% U235

    Energy Technology Data Exchange (ETDEWEB)

    Conway, K. C.

    2002-02-28

    The uranium and transuranic content of site soils and building rubble can be accurately measured using a NaI(Tl) well counter, without significant soil preparation. Accurate measurements of total uranium in uranium-transuranic mixtures can be made, despite a wide range (0.3% to 97%) of uranium enrichment, sample mass, and activity concentrations. The appropriate uranium scaling factors needed to include the undetected uranium isotopes, particularly U 234 can be readily determined on a sample by sample basis as a part of the field analysis, by comparing the relative response of the U 235 186 keV peak versus the K shell X rays of U 238 , U 235, and their immediate ingrowth daughters. The ratio of the two results is a sensitive and accurate predictor of the uranium enrichment and scaling factors. The case study will illustrate how NaI(Tl) gamma spectrometry was used to provide rapid turnaround uranium and transuranic activity levels for soil and building rubble with sample by sample determination of the appropriate scaling factor to include the U234 and Uranium238 content.

  2. Use of delayed gamma rays for active non-destructive assay of {sup 235}U irradiated by pulsed neutron source (plasma focus)

    Energy Technology Data Exchange (ETDEWEB)

    Andola, Sanjay; Niranjan, Ram [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Kaushik, T.C., E-mail: tckk@barc.gov.in [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Rout, R.K. [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Kumar, Ashwani; Paranjape, D.B.; Kumar, Pradeep; Tomar, B.S.; Ramakumar, K.L. [Radioanalytical Chemistry Division, Bhabha Atomic Research Centre, Mumbai 400085 (India); Gupta, S.C. [Applied Physics Division, Bhabha Atomic Research Centre, Mumbai 400085 (India)

    2014-07-01

    A pulsed neutron source based on plasma focus device has been used for active interrogation and assay of {sup 235}U by monitoring its delayed high energy γ-rays. The method involves irradiation of fissile material by thermal neutrons obtained after moderation of a burst of neutrons emitted upon fusion of deuterium in plasma focus (PF) device. The delayed gamma rays emitted from the fissile material as a consequence of induced fission were detected by a large volume sodium iodide (NaI(Tl)) detector. The detector is coupled to a data acquisition system of 2k input size with 2k ADC conversion gain. Counting was carried out in pulse height analysis mode for time integrated counts up to 100 s while the temporal profile of delayed gamma has been obtained by counting in multichannel scaling mode with dwell time of 50 ms. To avoid the effect of passive (natural) and active (from surrounding materials) backgrounds, counts have been acquired for gamma energy between 3 and 10 MeV. The lower limit of detection of {sup 235}U in the oxide samples with this set-up is estimated to be 14 mg.

  3. R-matrix analysis of {sup 235}U neutron transmission and cross sections in the energy range 0 to 2.25 keV

    Energy Technology Data Exchange (ETDEWEB)

    Leal, L.C.; Derrien, H.; Larson, N.M.; Wright, R.Q.

    1997-11-01

    This document describes a new R-matrix analysis of {sup 235}U cross section data in the energy range from 0 to 2,250 eV. The analysis was performed with the computer code SAMMY, that has recently been updated to permit, for the first time, inclusion of both differential and integral data within the analysis process. Fourteen differential data sets and six integral quantities were used in this evaluation: two measurements of fission plus capture, one of fission plus absorption, six of fission alone, two of transmission, and one of eta, plus standard values of thermal cross sections for fission, capture, and scattering, and of K1 and the Westcott g-factors for both fission and absorption. An excellent representation was obtained for the high-resolution transmission, fission, and capture cross-section data as well as for the integral quantities. The result is a single set of resonance parameters spanning the entire range up to 2,250 eV, a decided improvement over the present ENDF/VI evaluation, in which eleven discrete resonance parameter sets are required to cover that same energy range. This new evaluation is expected to greatly improve predictability of the criticality safety margins for nuclear systems in which {sup 235}U is present.

  4. Acoustic Emission tomography based on simultaneous algebraic reconstruction technique to visualize the damage source location in Q235B steel plate

    Science.gov (United States)

    Jiang, Yu; Xu, Feiyun; Xu, Bingsheng

    2015-12-01

    Acoustic Emission (AE) tomography based on Simultaneous Algebraic Reconstruction Technique (SART), which combines the traditional location algorithm with the SART algorithm by using AE events as its signal sources, is a new visualization method for inspecting and locating the internal damages in the structure. In this paper, the proposed method is applied to examine and visualize two man-made damage source locations in the Q235B steel plate to validate its effectiveness. Firstly, the Q235B steel plate with two holes specimen is fabricated and the pencil lead break (PLB) signal is taken as the exciting source for AE tomography.Secondly, A 6-step description of the SART algorithm is provided and the three dimensional(3D)image contained the damage source locations is visualized by using the proposed algorithm in terms of a locally varying wave velocity distribution. It is shown that the AE tomography based on SART has great potential in the application of structure damage detection. Finally, to further improve the quality of 3D imaging, the Median Filter and the Adaptive Median Filter are used to reduce the noises resulting from AE tomography. The experiment results indicate that Median Filter is the optimal method to remove Salt & Pepper noises.

  5. Screening of GJB2 235delC mutation and mtDNA 12S rRNA A1555G mutation in Chongqing children with non-syndromic hearing impairment%非综合征性耳聋儿童GJB2 235delC及线粒体DNA 12S rRNA A1555G突变分析

    Institute of Scientific and Technical Information of China (English)

    王冰; 姚红兵; 徐洁; 周媛; 汪武

    2009-01-01

    目的 对耳聋患儿进行GJB2基因、线粒体DNA A1555G位点突变检测,为遗传性耳聋提供诊断依据.方法 对195例耳聋患儿进行遗传性耳聋问卷调查、全面的体格检查、耳鼻咽喉专科检查以及听力学评估(包括纯音测听、脑干诱发电位和耳声发射).对195例非综合征性感音神经性耳聋患儿及100例健康对照个体分别进行GJB2基因235delC突变、线粒体DNA 12S rRNA基因A1555G点突变的限制性内切酶分析.结果 195例患儿者中发现GJB2基因235delc纯合突变、235delC与176-191del16复合及235delC与299-300delAT复合突变等共46例耳聋患儿与GJB2基因突变有关,占23.58%.病患组235delC等位基因频率为18.44%,对照组为2.00%(P<0.01).同时在患儿组还发现了7例线粒体DNA A1555G突变,对照组未发现线粒体DNA A1555G突变.结论 重庆市非综合征型耳聋患儿存在较高的GJB2基因235delC和线粒体DNA 12S rRNA基因A1555G突变发生率,高于全国平均水平.耳聋基因诊断技术可以应用在地区性耳聋病因调查中有重要的意义.对基因型-表现型相关性的研究对遗传性耳聋的治疗及预期疗效判断、遗传咨询、产前诊断等具有重要意义.%Objective To detect the mutations of GJB2 and mtDNA A1555G in Chongqing children with hereditary hearing loss. Methods Totally 195 deaf children were included to identify their medical history of hearing loss, use of aminoglycosides, and other clinical abnormalities through filling a questionnaire by their parents, with 100 normal children as control. The audiological and neurological examinations of these children were conducted, including otoseopy, pure-tone audiometry, acoustic brainstem evoked response (ABR) and otoaeoustic emission. GJB2 gene 235delC mutation and mtDNA A1555G mutation were detected with specific restriction enzyme digestion. Results Homozygous deletion C at position 233-235 of GJB2 (235delC) resul-ted in frameshifi mutation. GJB2

  6. Standard practice for the determination of 237Np, 232Th, 235U and 238U in urine by inductively coupled plasma-Mass spectrometry (ICP-MS) and gamma ray spectrometry.

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2005-01-01

    1.1 This practice covers the separation and preconcentration of neptunium-237 (237Np), thorium-232 (232Th), uranium-235 (235U) and uranium-238 (238U) from urine followed by quantitation using ICP-MS. 1.2 This practice can be used to support routine bioassay programs. The minimum detectable concentrations (MDC) for this method, taking the preconcentration factor into account, are approximately 1E-2Bq for 237Np (0.38ng), 2E-6Bq for 232Th (0.50ng), 4E-5Bq for 235U (0.50ng) and 6E-6Bq for 238U (0.48ng). 1.3 This standard does not purport to address all of the safety problems, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  7. Folding angle and excitation energy of fragments from 235U(n th,f) and 252Cf(sf) reactions

    Science.gov (United States)

    Haninger, T.; Hartmann, F. J.; Hofmann, P.; Kim, Y. S.; Lotfranaei, M. S.; von Egidy, T.; Märten, H.; Ruben, A.

    1994-05-01

    Coincident fragments from 235U(n th,f) and 252Cf(sf) reactions were investigated with a doublearm fission-fragment spectrometer and PIN-diode arrays. Based on the measurement of kinetic energy, velocity and direction of complementary fragments the total kinetic energy, the total mass, the individual fragment masses, the total number of emitted neutrons as well as the folding angle were deduced event by event. A nearly linear correlation between average folding angle and average total excitation energy of the fragments (and, consequently, the average number of neutrons) was found. Fragment deflection by prompt neutron emission is accordingly described by a complex statistical evaporation model in connection with a semi-empirical calculation of energy partition in nuclear fission. In addition, the folding-angle distribution due to ternary fission is estimated. All experimental fragment distributions and correlations are well repro- duced by the model calculations.

  8. Standard specification for uranium oxides with a 235U content of less than 5 % for dissolution prior to conversion to nuclear-grade uranium dioxide

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2005-01-01

    1.1 This specification covers uranium oxides, including processed byproducts or scrap material (powder, pellets, or pieces), that are intended for dissolution into uranyl nitrate solution meeting the requirements of Specification C788 prior to conversion into nuclear grade UO2 powder with a 235U content of less than 5 %. This specification defines the impurity and uranium isotope limits for such urania powders that are to be dissolved prior to processing to nuclear grade UO2 as defined in Specification C753. 1.2 This specification provides the nuclear industry with a general standard for such uranium oxide powders. It recognizes the diversity of conversion processes and the processes to which such powders are subsequently to be subjected (for instance, by solvent extraction). It is therefore anticipated that it may be necessary to include supplementary specification limits by agreement between the buyer and seller. 1.3 The scope of this specification does not comprehensively cover all provisions for prevent...

  9. High accuracy determination of the $^{238}$U/$^{235}$U fission cross section ratio up to $\\sim$1 GeV at n_TOF (CERN)

    CERN Document Server

    Paradela, C; Tarrío, D; Leal-Cidoncha, E; Leong, L S; Tassan-Got, L; Naour, C Le; Duran, I; Colonna, N; Audouin, L; Mastromarco, M; Meo, S Lo; Ventura, A; Altstadt, S; Andrzejewski, J; Barbagallo, M; Bécares, V; Bečvář, F; Belloni, F; Berthoumieux, E; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviño, F; Cano-Ott, D; Carrapiço, C; Cerutti, F; Chiaveri, E; Chin, M; Cortés, G; Cortés-Giraldo, M A; Cosentino, L; Diakaki, M; Domingo-Pardo, C; Dressler, R; Eleftheriadis, C; Ferrari, A; Finocchiaro, P; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Guerrero, C; Gunsing, F; Gurusamy, P; Heinitz, S; Jenkins, D G; Jericha, E; Käppeler, F; Karadimos, D; Kivel, N; Kokkoris, M; Krtička, M; Kroll, J; Langer, C; Lederer, C; Leeb, H; Losito, R; Manousos, A; Marganiec, J; Martínez, T; Massimi, C; Mastinu, P; Mendoza, E; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondalaers, W; Musumarra, A; Pavlik, A; Perkowski, J; Plompen, A; Praena, J; Quesada, J; Rauscher, T; Reifarth, R; Riego, A; Roman, F; Rubbia, C; Sarmento, R; Saxena, A; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; Tain, J L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Versaci, R; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiß, C; Wright, T; Žugec, P

    2015-01-01

    The $^{238}$U to $^{235}$U fission cross section ratio has been determined at n_TOF up to $\\sim$1 GeV, with two different detection systems, in different geometrical configurations. A total of four datasets have been collected and compared. They are all consistent to each other within the relative systematic uncertainty of 3-4%. The data collected at n_TOF have been suitably combined to yield a unique fission cross section ratio as a function of the neutron energy. The result confirms current evaluations up to 200 MeV. A good agreement is also observed with theoretical calculations based on the INCL++/Gemini++ combination up to the highest measured energy. The n_TOF results may help solving a long-standing discrepancy between the two most important experimental dataset available so far above 20 MeV, while extending the neutron energy range for the first time up to $\\sim$1 GeV.

  10. 美国花235亿造“太阳”:192束激光打造恒星温度

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    日前,被誉为"人造太阳"的美国国家点火装置NIF完成了首次综合点火实验——192束激光系统发射的能量打造出600万华氏度高温,这相当于恒星或大行星核心的温度。NIF作为全球最大的激光核聚变装置,从1997年开始建造起已经花掉了纳税人35.5亿美元(约合人民币235亿元)。研究人员不惜代价不仅为了研

  11. Weld pool temperatures of steel S235 while applying a controlled short-circuit gas metal arc welding process and various shielding gases

    Science.gov (United States)

    Kozakov, R.; Schöpp, H.; Gött, G.; Sperl, A.; Wilhelm, G.; Uhrlandt, D.

    2013-11-01

    The temperature determination of liquid metals is difficult and depends strongly on the emissivity. However, the surface temperature distribution of the weld pool is an important characteristic of an arc weld process. As an example, short-arc welding of steel with a cold metal transfer (CMT) process is considered. With optical emission spectroscopy in the spectral region between 660 and 840 nm and absolute calibrated high-speed camera images the relation between temperature and emissivity of the weld pool is determined. This method is used to obtain two-dimensional temperature profiles in the pictures. Results are presented for welding materials (wire G3Si1 on base material S235) using different welding CMT processes with CO2 (100%), Corgon 18 (18% CO2 + 82% Ar), VarigonH6 (93.5% Ar + 6.5% H2) and He (100%) as shielding gases. The different gases are used to study their influence on the weld pool temperature.

  12. {2-[(3,5-Dichloro-2-oxidobenzylideneamino-κ2N,O]-3-methylpentanoato-κO}(N,N′-dimethylformamide-κOcopper(II

    Directory of Open Access Journals (Sweden)

    Xiao Zhen Feng

    2008-05-01

    Full Text Available In the title compound, [Cu(C13H13Cl2NO3(C3H7NO], the CuII atom is coordinated in a slightly distorted square-planar geometry by two O atoms and one N atom from the tridentate chiral ligand 2-[(3,5-dichloro-2-oxidobenzylideneamino]-3-methylpentanoate and by one O atom from dimethylformamide. In the crystal structure, the Cu atom forms contacts with Cl and O atoms of two units (Cu...Cl and Cu...O = 3.401 and 2.947 Å, respectively, thereby forming an approximately octahedral arrangement. A three-dimensional network is constructed through Cl...Cu, O...Cu, Cl...Cl contacts and C—H...O hydrogen bonds.

  13. Survival and Predictive Factors of Lethality in Hemodyalisis: D/I Polymorphism of The Angiotensin I-Converting Enzyme and of the Angiotensinogen M235T Genes

    Directory of Open Access Journals (Sweden)

    Mauro Alves

    2014-09-01

    Full Text Available Background: End-stage kidney disease patients continue to have markedly increased cardiovascular disease morbidity and mortality. Analysis of genetic factors connected with the renin-angiotensin system that influences the survival of the patients with end-stage kidney disease supports the ongoing search for improved outcomes. Objective: To assess survival and its association with the polymorphism of renin-angiotensin system genes: angiotensin I-converting enzyme insertion/deletion and angiotensinogen M235T in patients undergoing hemodialysis. Methods: Our study was designed to examine the role of renin-angiotensin system genes. It was an observational study. We analyzed 473 chronic hemodialysis patients in four dialysis units in the state of Rio de Janeiro. Survival rates were calculated by the Kaplan-Meier method and the differences between the curves were evaluated by Tarone-Ware, Peto-Prentice, and log rank tests. We also used logistic regression analysis and the multinomial model. A p value ≤ 0.05 was considered to be statistically significant. The local medical ethics committee gave their approval to this study. Results: The mean age of patients was 45.8 years old. The overall survival rate was 48% at 11 years. The major causes of death were cardiovascular diseases (34% and infections (15%. Logistic regression analysis found statistical significance for the following variables: age (p = 0.000038, TT angiotensinogen (p = 0.08261, and family income greater than five times the minimum wage (p = 0.03089, the latter being a protective factor. Conclusions: The survival of hemodialysis patients is likely to be influenced by the TT of the angiotensinogen M235T gene.

  14. The application of EOQ and lead time crashing cost models in material with limited life time (Case study: CN-235 Aircraft at PT Dirgantara Indonesia)

    Science.gov (United States)

    Agustina Hidayat, Yosi; Ria Kasanah, Aprilia; Yudhistira, Titah

    2016-02-01

    PT. Dirgantara Indonesia, one of State Owned Enterprises engaging in the aerospace industry, targets to control 30% of world market for light and medium sized aircraft. One type of the aircrafts produced by PT. DI every year is CN-235. Currently, the cost of material procurement reaches 50% of the total cost of production. Material has a variety of characteristics, one of which is having a lifetime. The demand characteristic of the material with expiration for the CN-235 aircraft is deterministic. PT DI does not have any scientific background for its procurement of raw material policy. In addition, there are two methods of transportation used for delivering materials, i.e. by land and air. Each method has different lead time. Inventory policies used in this research are deterministic and probabilistic. Both deterministic and probabilistic single and multi-item inventory policies have order quantity, time to order, reorder point, and lead time as decision variables. The performance indicator for this research is total inventory cost. Inventory policy using the single item EOQ and considering expiration factor inventory results in a reduction in total costs up to 69.58% and multi item results in a decrease in total costs amounted to 71.16%. Inventory policy proposal using the model of a single item by considering expiration factor and lead time crashing cost results in a decrease in total costs amounted to 71.5% and multi item results in a decrease in total costs amounted to 71.62%. Subsequently, wasted expired materials, with the proposed models have been successfully decreased to 95%.

  15. Survival and Predictive Factors of Lethality in Hemodyalisis: D/I Polymorphism of The Angiotensin I-Converting Enzyme and of the Angiotensinogen M235T Genes

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Mauro, E-mail: malves@cardiol.br; Silva, Nelson Albuquerque de Souza e; Salis, Lucia Helena Alvares; Pereira, Basilio de Bragança; Godoy, Paulo Henrique; Nascimento, Emília Matos do [Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ (Brazil); Oliveira, Jose Mario Franco [Universidade Federal Fluminense, Niterói, RJ (Brazil)

    2014-09-15

    End-stage kidney disease patients continue to have markedly increased cardiovascular disease morbidity and mortality. Analysis of genetic factors connected with the renin-angiotensin system that influences the survival of the patients with end-stage kidney disease supports the ongoing search for improved outcomes. To assess survival and its association with the polymorphism of renin-angiotensin system genes: angiotensin I-converting enzyme insertion/deletion and angiotensinogen M235T in patients undergoing hemodialysis. Our study was designed to examine the role of renin-angiotensin system genes. It was an observational study. We analyzed 473 chronic hemodialysis patients in four dialysis units in the state of Rio de Janeiro. Survival rates were calculated by the Kaplan-Meier method and the differences between the curves were evaluated by Tarone-Ware, Peto-Prentice, and log rank tests. We also used logistic regression analysis and the multinomial model. A p value ≤ 0.05 was considered to be statistically significant. The local medical ethics committee gave their approval to this study. The mean age of patients was 45.8 years old. The overall survival rate was 48% at 11 years. The major causes of death were cardiovascular diseases (34%) and infections (15%). Logistic regression analysis found statistical significance for the following variables: age (p = 0.000038), TT angiotensinogen (p = 0.08261), and family income greater than five times the minimum wage (p = 0.03089), the latter being a protective factor. The survival of hemodialysis patients is likely to be influenced by the TT of the angiotensinogen M235T gene.

  16. Measurements of the neutron-induced fission cross sections of /sup 240/Pu and /sup 242/Pu relative to /sup 235/U. [0. 02 to 30 MeV, tables

    Energy Technology Data Exchange (ETDEWEB)

    Behrens, J. W.; Browne, J. C.; Carlson, G. W.

    1976-03-01

    A continuation is given of the fission-cross-section ratio measurements in progress at the Lawrence Livermore Laboratory. Preliminary results are provided for the /sup 240/Pu//sup 235/U and /sup 242/Pu//sup 235/U ratios from 0.02 to 30 MeV and 0.1 to 30 MeV, respectively. Using the threshold-cross-section method, the ratios were normalized to the values 1.368 +- 0.030 and 1.116 +- 0.025, respectively, from 1.75 to 4.00 MeV.

  17. Synthesis and Characterization of 2-(3,5-Dinitrophenyl)-4-nitro-1,2,3-triazole-1-oxide%2-(3,5-二硝基苯)-4-硝基三唑-1-氧化物的合成及表征

    Institute of Scientific and Technical Information of China (English)

    杨威; 王伯周; 李亚南; 周诚; 王友兵

    2012-01-01

    Starting from glyoxal, phenylhydrazine and hydrochloride hydroxylamine, 2-(3,5-dinitrophenyl)-4-nitro -1,2,3 -triazole -1 -oxide ( TNPTO) was synthesized by the processes of condensation, oximation, cyclization and nitration in overall yield of 45% and purity of 99%. The target compound and its intermediates were characterized with 1R, 1H NMR and elemental analysis. The reaction mechanism of cyclization in the solution of cupric sulphate-pyridine-water was proposed.%以乙二醛、苯胼和盐酸羟胺为起始原料,经缩合、肟化,生成中间体肟基苯腙,加入硫酸铜-吡啶-水体系,缩合环化得到2-苯基三唑-1-氧化物(PTO),然后硝硫混酸硝化合成了2-(3,5-二硝基苯)-4-硝基三唑-1-氧化物(TNPTO),总收率45%,中间体和TNPTO均通过红外光谱、核磁、质谱以及元素分析等进行了结构表征.初步探讨了铜盐作用下合成三唑环的反应机理.

  18. Uranium isotopic ratio measurements ({sup 235}U/{sup 238}U) by laser ablation high resolution inductively coupled plasma mass spectrometry for environmental radioactivity monitoring - {sup 235}U/{sup 238}U isotope ratio analysis by LA-ICP-MS-HR for environmental radioactivity monitoring

    Energy Technology Data Exchange (ETDEWEB)

    David, K.; Mokili, M.B.; Rousseau, G.; Deniau, I.; Landesman, C. [SUBATECH, Ecole des Mines de Nantes, Universite de Nantes, CNRS/IN2P3, 4 rue Alfred Kastler, 44307 Nantes cedex 3 (France)

    2014-07-01

    The protection of the aquatic and terrestrial environments from a broad range of contaminants spread by nuclear activities (nuclear plants, weapon tests or mining) require continuous monitoring of long-lives radionuclides that were released into the environment. The precise determination of uranium isotope ratios in both natural and potential contaminated samples is of primary concern for the nuclear safeguards and the control of environmental contamination. As an example, analysis of environmental samples around nuclear plants are carried out to detect the traces in the environment originating from nuclear technology activities. This study deals with the direct analysis of {sup 235}U/{sup 238}U isotope ratios in real environmental solid samples performed with laser ablation (LA)-HR-ICP-MS. A similar technique has already been reported for the analysis of biological samples or uranium oxide particles [1,2] but to our knowledge, this was never applied on real environmental samples. The high sensitivity, rapid acquisition time and low detection limits are the main advantages of high resolution ICP-MS for accurate and precise isotope ratio measurements of uranium at trace and ultra-trace levels. In addition, the use of laser ablation allows the analysis of solid samples with minimal preparation. A a consequence, this technique is very attractive for conducting rapid direct {sup 235}U/{sup 238}U isotope ratio analysis on a large set of various matrix samples likely to be encountered in environmental monitoring such as corals, soils, sands, sediments, terrestrial and marine bio-indicators. For the present study, LA-ICP-MS-HR analyses are performed using a New Wave UP213 nano-second Nd:YAG laser coupled to a Thermo Element-XR high resolution mass spectrometer. Powdered samples are compacted with an hydraulic press (5 tons) in order to obtain disk-shaped pellet (10-13 mm in diameter and 2 mm in thickness). The NIST612 reference glass is used for LA-ICP-MS-HR tuning and as

  19. 235例维吾尔族胎儿孤立性轻度侧脑室增宽临床预后研究%The study of the ultrasound dingnosis of pregnancy outcomes for 235 cases of the Uighur fetal isolated ventricle widened and clinial outcome

    Institute of Scientific and Technical Information of China (English)

    庞晨

    2012-01-01

    目的 探讨超声诊断235例维吾尔族胎儿孤立性侧脑室增宽的妊娠结局及临床预后.方法 回顾性分析我院产前超声诊断235例维吾尔族胎儿孤立性轻度侧脑室增宽的资料,并进行追踪随访.重点观察临床预后.结果 235例胎儿侧脑室增宽10 - 15mm,其中200例侧脑室增宽10 - 12mm,35例增宽12 - 15mm.随访中有7例侧脑室增宽至16-18mm,诊断为脑积水,其中5胎选择引产(其中1胎证实18—三体综合症),2胎出生后10天内死亡.其余28胎活产病例中(男胎16例,女胎12例),1例于出生一月内死亡,27例存活,其中1例发生神经系统发育迟滞,余26例发育正常.其余于妊娠晚期及出生后复查IMV自然消退.结论 超声检查是胎儿IMV产前诊断的有效方法,IMV胎儿总体预后较好,但应重视出生后随诊.%Objective: To investigate the ultrasound diagnosis of pregnancy outcomes of 233 cases of the Uighur fetal isolated lateral ventricle widened and clinical outcome. Methods; A retrospective analysis of hospital prenatal ultrasound diagnosis of 235 cases of the Uighur fetal isolated mild lateral ventricle widened information, and were followed up. Focus on clinical prognosis. Results 235 cases of fetal lateral ventricle widened 10 - 15mm, 200 cases of lateral ventricle, widened 10-12mm, 35 cases of widened 12 -15mm. Follow - up, seven cases of lateral ventricle widened to 16 - 18mm, diagnosed with hydrocephalus, 5 fetal induction of labor ( a fetal confirmed 18 trisomy syndrome) , within 10 days after the birth of the two tire death. The remaining 28 live births cases (16 cases of male fetuses, female fetuses, 12 cases) , 1 case of death, bom January 27 cases of survival, of which one cases of retardation of the nervous system occurs, the remaining 26 cases of normal development. The rest of the late in pregnancy and birth IMV check after natural retreat. Conclusion; Ultrasound is an effective method for prenatal diagnosis of fetal IMV, the IMV

  20. The dual PI3K/mTOR inhibitor NVP-BEZ235 induces tumor regression in a genetically engineered mouse model of PIK3CA wild-type colorectal cancer.

    Directory of Open Access Journals (Sweden)

    Jatin Roper

    Full Text Available To examine the in vitro and in vivo efficacy of the dual PI3K/mTOR inhibitor NVP-BEZ235 in treatment of PIK3CA wild-type colorectal cancer (CRC.PIK3CA mutant and wild-type human CRC cell lines were treated in vitro with NVP-BEZ235, and the resulting effects on proliferation, apoptosis, and signaling were assessed. Colonic tumors from a genetically engineered mouse (GEM model for sporadic wild-type PIK3CA CRC were treated in vivo with NVP-BEZ235. The resulting effects on macroscopic tumor growth/regression, proliferation, apoptosis, angiogenesis, and signaling were examined.In vitro treatment of CRC cell lines with NVP-BEZ235 resulted in transient PI3K blockade, sustained decreases in mTORC1/mTORC2 signaling, and a corresponding decrease in cell viability (median IC(50 = 9.0-14.3 nM. Similar effects were seen in paired isogenic CRC cell lines that differed only in the presence or absence of an activating PIK3CA mutant allele. In vivo treatment of colonic tumor-bearing mice with NVP-BEZ235 resulted in transient PI3K inhibition and sustained blockade of mTORC1/mTORC2 signaling. Longitudinal tumor surveillance by optical colonoscopy demonstrated a 97% increase in tumor size in control mice (p = 0.01 vs. a 43% decrease (p = 0.008 in treated mice. Ex vivo analysis of the NVP-BEZ235-treated tumors demonstrated a 56% decrease in proliferation (p = 0.003, no effects on apoptosis, and a 75% reduction in angiogenesis (p = 0.013.These studies provide the preclinical rationale for studies examining the efficacy of the dual PI3K/mTOR inhibitor NVP-BEZ235 in treatment of PIK3CA wild-type CRC.

  1. Ground water contamination with (238)U, (234)U, (235)U, (226)Ra and (210)Pb from past uranium mining: cove wash, Arizona.

    Science.gov (United States)

    Dias da Cunha, Kenya Moore; Henderson, Helenes; Thomson, Bruce M; Hecht, Adam A

    2014-06-01

    The objectives of the study are to present a critical review of the (238)U, (234)U, (235)U, (226)Ra and (210)Pb levels in water samples from the EPA studies (U.S. EPA in Abandoned uranium mines and the Navajo Nation: Red Valley chapter screening assessment report. Region 9 Superfund Program, San Francisco, 2004, Abandoned uranium mines and the Navajo Nation: Northern aum region screening assessment report. Region 9 Superfund Program, San Francisco, 2006, Health and environmental impacts of uranium contamination, 5-year plan. Region 9 Superfund Program, San Franciso, 2008) and the dose assessment for the population due to ingestion of water containing (238)U and (234)U. The water quality data were taken from Sect. "Data analysis" of the published report, titled Abandoned Uranium Mines Project Arizona, New Mexico, Utah-Navajo Lands 1994-2000, Project Atlas. Total uranium concentration was above the maximum concentration level for drinking water (7.410-1 Bq/L) in 19 % of the water samples, while (238)U and (234)U concentrations were above in 14 and 17 % of the water samples, respectively. (226)Ra and (210)Pb concentrations in water samples were in the range of 3.7 × 10(-1) to 5.55 × 102 Bq/L and 1.11 to 4.33 × 102 Bq/L, respectively. For only two samples, the (226)Ra concentrations exceeded the MCL for total Ra for drinking water (0.185 Bq/L). However, the (210)Pb/(226)Ra ratios varied from 0.11 to 47.00, and ratios above 1.00 were observed in 71 % of the samples. Secular equilibrium of the natural uranium series was not observed in the data record for most of the water samples. Moreover, the (235)U/(total)U mass ratios ranged from 0.06 to 5.9 %, and the natural mass ratio of (235)U to (total)U (0.72 %) was observed in only 16 % of the water samples, ratios above or below the natural ratio could not be explained based on data reported by U.S. EPA. In addition, statistical evaluations showed no correlations among the distribution of the radionuclide concentrations

  2. TEM analysis and wear resistance of the ceramic coatings on Q235 steel prepared by hybrid method of hot-dipping aluminum and plasma electrolytic oxidation

    Energy Technology Data Exchange (ETDEWEB)

    Lu Lihong [State Key Laboratory of Metastable Materials Science and Technology, College of Materials Science and Engineering, Yanshan University, Qinhuangdao 066004 (China); Science and Research Department, Chinese People' s Armed Police Academy, Langfang 065000 (China); Zhang Jingwu [State Key Laboratory of Metastable Materials Science and Technology, College of Materials Science and Engineering, Yanshan University, Qinhuangdao 066004 (China); Shen Dejiu, E-mail: sdj217@ysu.edu.cn [State Key Laboratory of Metastable Materials Science and Technology, College of Materials Science and Engineering, Yanshan University, Qinhuangdao 066004 (China); Wu Lailei; Jiang Guirong [State Key Laboratory of Metastable Materials Science and Technology, College of Materials Science and Engineering, Yanshan University, Qinhuangdao 066004 (China); Li Liang [State Key Laboratory of Automotive Safety and Energy, Tsinghua University, Beijing 100084 (China)

    2012-01-25

    Highlights: Black-Right-Pointing-Pointer Transmission electron microscopy (TEM) was firstly used to analyze the phase composition of the ceramic coatings. Black-Right-Pointing-Pointer The phase composition of the ceramic coatings is mainly amorphous phase and crystal Al{sub 2}O{sub 3} oxides. Black-Right-Pointing-Pointer The cross-section micro-hardness of the treated samples was investigated, the hardness of the ceramic coatings is about HV1300. Black-Right-Pointing-Pointer The wear resistance of the PEO samples is about 3 times higher than that of the heat treated 45 steel. - Abstract: The hybrid method of PEO and hot-dipping aluminum (HDA) was employed to deposit composite ceramic coatings on the surface of Q235 steel. The composition of the composite coatings was investigated with X-ray diffraction (XRD) and transmission electron microscopy (TEM), respectively. The cross-section microstructure and micro-hardness of the treated specimens were investigated and analyzed with scanning electron microscopy (SEM) and microscopic hardness meter (MHM), respectively. The wear resistance of the ceramic coatings was investigated by a self-made rubbing wear testing machine. The results indicate that metallurgical bonding can be observed between the ceramic coatings and the steel substrate. There are many micro-pores and micro-cracks, which act as the discharge channels and result of quick and non-uniform cooling of melted sections in the plasma electrolytic oxidation ceramic coatings. The phase composition of the ceramic coatings is mainly composed of amorphous phase and crystal Al{sub 2}O{sub 3} oxides. The crystal Al{sub 2}O{sub 3} phase includes {kappa}-Al{sub 2}O{sub 3}, {theta}-Al{sub 2}O{sub 3} and {beta}-Al{sub 2}O{sub 3}. The grain size of the {kappa}-Al{sub 2}O{sub 3} crystal is quite non-uniform. The hardness of the ceramic coatings is about HV1300 and 10 times higher than that of the Q235 substrate, which was favorable to the better wear resistance of the ceramic

  3. The M235T polymorphism in the AGT gene and CHD risk: evidence of a Hardy-Weinberg equilibrium violation and publication bias in a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Mohammad Hadi Zafarmand

    Full Text Available BACKGROUND: The M235T polymorphism in the AGT gene has been related to an increased risk of hypertension. This finding may also suggest an increased risk of coronary heart disease (CHD. METHODOLOGY/PRINCIPAL FINDINGS: A case-cohort study was conducted in 1,732 unrelated middle-age women (210 CHD cases and 1,522 controls from a prospective cohort of 15,236 initially healthy Dutch women. We applied a Cox proportional hazards model to study the association of the polymorphism with acute myocardial infarction (AMI (n = 71 and CHD. In the case-cohort study, no increased risk for CHD was found under the additive genetic model (hazard ratio [HR] = 1.20; 95% confidence interval [CI], 0.86 to 1.68; P = 0.28. This result was not changed by adjustment (HR = 1.17; 95% CI, 0.83 to 1.64; P = 0.38 nor by using dominant, recessive and pairwise genetic models. Analyses for AMI risk under the additive genetic model also did not show any statistically significant association (crude HR = 1.14; 95% CI, 0.93 to 1.39; P = 0.20. To evaluate the association, a comprehensive systematic review and meta-analysis were undertaken of all studies published up to February 2007 (searched through PubMed/MEDLINE, Web of Science and EMBASE. The meta-analysis (38 studies with 13284 cases and 18722 controls showed a per-allele odds ratio (OR of 1.08 (95% CI, 1.01 to 1.15; P = 0.02. Moderate to large levels of heterogeneity were identified between studies. Hardy-Weinberg equilibrium (HWE violation and the mean age of cases were statistically significant sources of the observed variation. In a stratum of non-HWE violation studies, there was no effect. An asymmetric funnel plot, the Egger's test (P = 0.066, and the Begg-Mazumdar test (P = 0.074 were all suggestive of the presence of publication bias. CONCLUSIONS/SIGNIFICANCE: The pooled OR of the present meta-analysis, including our own data, presented evidence that there is an increase in the risk of CHD conferred by the M235T variant

  4. The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure.

    Science.gov (United States)

    Schelleman, Hedi; Klungel, Olaf H; Witteman, Jacqueline C M; Hofman, Albert; van Duijn, Cornelia M; de Boer, Anthonius; Stricker, Bruno H C H

    2006-07-01

    Despite the availability of a variety of effective antihypertensive drugs, inadequate control of blood pressure is common in hypertensive patients. The aim of this study was investigate whether the alpha-adducin G460W polymorphism or angiotensinogen M235T polymorphism has an effect on the mean difference in blood pressure in subjects using antihypertensive drugs. Data from the Rotterdam Study, a population-based prospective cohort study in the Netherlands, was used. This study started in 1990 and included 7983 subjects of 55 years and older. Data from three examination rounds were used. Subjects were included when their blood pressure was elevated at 1 or more examinations and/or a diuretic, beta-blocker, calcium antagonist, or ACE inhibitor was used. A marginal generalized linear model was used to assess the drug-gene interaction. In total, 3025 hypertensives were included. No drug-gene interaction on blood pressure levels was found. The mean difference in systolic blood pressure (SBP) between subjects with the W-allele and GG genotype of the alpha-adducin gene was for diuretic users 1.25 mmHg (95% CI:-2.86 to 5.35), for beta-blockers 0.02 mmHg (95% CI:-3.39 to 3.42), for calcium antagonists -0.70 mmHg (95% CI:-5.61 to 4.21), and for ACE inhibitors -3.50 mmHg (95% CI:-9.02 to 2.02). The mean difference in SBP between subjects with the TT and MM genotype was for diuretic users -2.33 mmHg (95% CI:-8.32 to 3.66), for beta-blocker -0.06 mmHg (95% CI:-4.91 to 4.79), for calcium antagonist 0.59 mmHg (95% CI:-5.95 to 7.13), and for ACE inhibitor -2.33 mmHg (95% CI:-9.66 to 5.01). The G460W polymorphism and the M235T polymorphism did not modify the difference in blood pressure levels among subjects who used diuretics, beta-blockers, calcium antagonists, or ACE inhibitors.

  5. Trace metal cycling and 238U/235U in New Zealand's fjords: Implications for reconstructing global paleoredox conditions in organic-rich sediments

    Science.gov (United States)

    Hinojosa, Jessica L.; Stirling, Claudine H.; Reid, Malcolm R.; Moy, Christopher M.; Wilson, Gary S.

    2016-04-01

    Reconstructing the history of ocean oxygenation provides insight into links between ocean anoxia, biogeochemical cycles, and climate. Certain redox-sensitive elements respond to changes in marine oxygen content through phase shifts and concomitant isotopic fractionation, providing new diagnostic proxies of past ocean hypoxia. Here we explore the behavior and inter-dependence of a suite of commonly utilized redox-sensitive trace metals (U, Mo, Fe, and Mn) and the emerging "stable" isotope system of U (238U/235U, or δ238U) in New Zealand fjords. These semi-restricted basins have chemical conditions spanning the complete redox spectrum from fully oxygenated to suboxic to intermittently anoxic/euxinic. In the anoxic water column, U and Mo concentrations decrease, while Fe and Mn concentrations increase. Similarly, signals of past euxinic conditions can be found by U, Mo, Fe, and Mn enrichment in the underlying sediments. The expected U isotopic shift toward a lower δ238U in the anoxic water column due to U(VI)-U(IV) reduction is not observed; instead, water column δ238U profiles are consistent in fjords of all oxygen content, falling within previously reported ranges for open ocean seawater (δ238U = -0.42 ± 0.07‰). Additionally, surface sediment δ238U results show evidence for competing U isotope fractionation processes. One site indicates increased export of 238U from seawater to the underlying sediments (fractionation between aqueous seawater U and particulate sediment U, or ΔU(aq)-U(solid) = -0.25‰), consistent with redox-driven fractionation. Another site suggests potential U(VI) adsorption-driven fractionation, reflecting increased export of 235U from seawater to sediments (ΔU(aq)-U(solid) = 0.25‰). We discuss several potential factors that could alter δ238U in waters and sediments beyond redox-driven shifts, including adsorption to organic matter in waters of high primary productivity, reaction rates for competing processes of U adsorption and

  6. Photodissociation dynamics of halogenated thiophenes at 235 nm: a resonance enhanced multiphoton ionization-time-of-flight (REMPI-TOF) study.

    Science.gov (United States)

    Kawade, Monali; Saha, Ankur; Upadhyaya, Hari P; Kumar, Awadhesh; Naik, Prakash D; Bajaj, P N

    2012-11-08

    The photodissociation dynamics of halogen-substituted thiophenes, namely, 2-chlorothiophene and 2-bromo-5-chlorothiophene, has been studied in a supersonic molecular beam around 235 nm, using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique, by detecting the nascent state of the primary halogen atoms. A single laser has been used for excitation of halothiophenes, as well as for the REMPI detection of photoproducts, namely, chlorine and bromine atoms, in their spin-orbit states X((2)P(3/2)) and X*((2)P(1/2)). We have determined the translational energy distribution, the recoil anisotropy parameter, β, and the spin-orbit branching ratio, for chlorine and bromine atom elimination channels. State-specific TOF profiles are converted into kinetic energy distributions, using a least-squares fitting method, taking into account the fragment anisotropies, β(ι). The TOF profiles for Cl, Cl*, Br, and Br* are found to be independent of laser polarization; i.e., the β is well characterized by a value of ~0.0, within the experimental uncertainties. For 2-chlorothiophene, we have observed two components for the Cl and only one component for the Cl* atom elimination channel in the translational energy distributions. The average translational energies for the fast and the slow components of the Cl channel are 3.0 ± 1.0 and 1.0 ± 0.5 kcal/mol, respectively. For Cl*, the average translational energy is 3.5 ± 1.0 kcal/mol. For 2-bromo-5-chlorothiophene, we have observed only one component for Cl, Cl*, Br, and Br* in the translational energy distributions. The average translational energies for the Cl and Cl* channels are 3.5 ± 1.0 and 5.0 ± 1.0 kcal/mol, respectively, whereas the average translational energies for the Br and Br* channels are 2.0 ± 1.0 and 3.5 ± 1.0 kcal/mol, respectively. The energy partitioning into the translational modes is interpreted with the help of various models, such as impulsive and statistical models. The ΔH(f)(298

  7. Neutron capture and fission reactions on 235U: cross sections, α-ratios and prompt γ-ray emission from fission

    Directory of Open Access Journals (Sweden)

    González-Romero E.

    2013-03-01

    Full Text Available According to the international benchmarks, and as it is mentioned in the NEA High Priority Request List, the 235U(n,γ cross section is of utmost importance for the operation and design of current and advanced nuclear reactors. The required accuracy in this energy region (100 eV to 2.25 keV ranges between 5% and 7%, to be compared with the present differences of 20% between the α-ratios in different evaluations. At n_TOF we have measured this cross section during the summer of 2012 using a fission tagging capture set-up. This new set-up has been tested successfully in 2010 and combines the n_TOF 4π Total Absorption Calorimeter with a series of MicroMegas fission detectors. The experiment has provided as well very valuable information on the distribution of energies and multiplicities of the γ-rays emitted prompt after capture and fission reactions. The very fresh data from this experiment will be presented for the first time, and their quality and expected results will be discussed in detail

  8. Fission Fragment Mass Distributions and Total Kinetic Energy Release of 235-Uranium and 238-Uranium in Neutron-Induced Fission at Intermediate and Fast Neutron Energies

    Energy Technology Data Exchange (ETDEWEB)

    Duke, Dana Lynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-11-12

    This Ph.D. dissertation describes a measurement of the change in mass distributions and average total kinetic energy (TKE) release with increasing incident neutron energy for fission of 235U and 238U. Although fission was discovered over seventy-five years ago, open questions remain about the physics of the fission process. The energy of the incident neutron, En, changes the division of energy release in the resulting fission fragments, however, the details of energy partitioning remain ambiguous because the nucleus is a many-body quantum system. Creating a full theoretical model is difficult and experimental data to validate existing models are lacking. Additional fission measurements will lead to higher-quality models of the fission process, therefore improving applications such as the development of next-generation nuclear reactors and defense. This work also paves the way for precision experiments such as the Time Projection Chamber (TPC) for fission cross section measurements and the Spectrometer for Ion Determination in Fission (SPIDER) for precision mass yields.

  9. Attenuation of a non-parallel beam of gamma radiation by thick shielding—application to the determination of the 235U enrichment with NaI detectors

    Science.gov (United States)

    Mortreau, Patricia; Berndt, Reinhard

    2005-09-01

    The traditional method used to determine the Uranium enrichment by nondestructive analysis is based on the "enrichment meter principle" [1]. It involves measuring the intensity of the 186 keV net peak area of 235U in "quasi-infinite" samples. A prominent factor, which affects the peak intensity, is the presence of gamma absorbing material (e.g., container wall, detector cover) between the sample and the detector. Its effect is taken into consideration in a commonly called "wall thickness" correction factor. Often calculated on the basis of approximations, its performance is adequate for small attenuation factors applicable to the case of narrow beams. However these approximations do not lead to precise results when wide non-parallel beams are attenuated through thick container walls. This paper is dedicated to the calculation by numerical integration of the geometrical correction factor ( Kwtc) which describes the effective mean path length of the radiation through the absorbing layer. This factor was calculated as a function of various measurement parameters (types and dimensions of the detector, of the collimator and of the shielding) for the most commonly used collimator shapes and detectors. Both coherent scattering (Rayleigh) and incoherent scattering (Compton) are taken into account for the calculation of the radiation interaction within the detector.

  10. Periodicities in the high-mass X-ray binary system RX J0146.9+6121/LS I+61 235

    CERN Document Server

    Sarty, Gordon E; Huziak, Richard; Catalan, Lionel J J; Luciuk, Diane; Crawford, Timothy R; Lane, David J; Pickard, Roger D; Grzybowski, Thomas A; Closas, Pere; Johnston, Helen; Balam, David; Wu, Kinwah

    2008-01-01

    The high-mass X-ray binary RX J0146.9+6121, with optical counterpart LS I+61 235 (V831 Cas), is an intriguing system on the outskirts of the open cluster NGC 663. It contains the slowest X-ray pulsar known with a pulse period of around 1400s and, primarily from the study of variation in the emission line profile of H alpha, it is known to have a Be decretion disk with a one-armed density wave period of approximately 1240d. Here we present the results of an extensive photometric campaign, supplemented with optical spectroscopy, aimed at measuring short time-scale periodicities. We find three significant periodicities in the photometric data at, in order of statistical significance, 0.34d, 0.67d and 0.10d. We give arguments to support the interpretation that the 0.34d and 0.10d periods could be due to stellar oscillations of the B type primary star and that the 0.67d period is the spin period of the Be star with a spin axis inclination of 23 +10 -8 degrees. We measured a systemic velocity of -37.0 +- 4.3 km/s c...

  11. Correlated V/R and IR photometric variations in the Be/X-ray binary LS I +61 235/RX J0146.9+6121

    CERN Document Server

    Reig, P; Coe, M J; Fabregat, J; Tarasov, A E; Zamanov, R K

    2000-01-01

    We report on the long-term variability of the Be/X-ray binary LS I +61 235/RX J0146.9+6121. New optical spectroscopic and infrared photometric observations confirm the presence of global one-arm oscillations in the circumstellar disc of the Be star and allow us to derive a V/R quasi-period of 1240+-30 days. Pronounced shell events, reminiscent of the spectacular variations in Be stars, are also seen. We have found that the J, H and K infrared photometric bands vary in correlation with the spectroscopic V/R variations, implying that the one-armed disc oscillations are prograde. The effect of the oscillations is not only seen in the Halpha line but also in the He I6678 and Paschen lines. Since these lines are formed at different radii in the equatorial disc of the Be star, such effect confirms the global nature of the perturbation. The Keplerian disc has been found to be denser than the average of a sample of isolated Be stars, which may be indicative of some kind of interaction with the compact companion. Fina...

  12. Cf-source-driven neutron-noise measurements of subcriticality for a 4. 95 wt% /sup 235/U-enriched uranyl fluoride solution cylinder

    Energy Technology Data Exchange (ETDEWEB)

    Mihalczo, J.T.; Kryter, R.T.; King, W.T.; Blakeman, E.D.

    1986-01-01

    A method for determining the reactivity of subcritical systems of fissile material, using neutron-noise power spectral density measurements in conjunction with a /sup 252/Cf source, has been tested in experiments with an aqueous solution containing uranium fluoride (4.95 wt% /sup 235/U). The kappasub(eff)-values obtained from the ratio of spectral densities G*/sub 12/G/sub 13//G/sub 11/G/sub 23/ agreed with those from break-frequency noise analysis and with bias-corrected transport theory calculations within the statistical uncertainty of the measurements. Corrections for the effects of spatial modes and source-detector locations appear to be well-understood, since measurements for a variety of source-detector positions resulted in essentially the same kappasub(eff)-values. Modal correction factors were such that ignoring them would result in higher values of kappasub(eff) than actually occur. The measurements have demonstrated the applicability of the /sup 252/Cf-source-driven neutron-noise analysis method to the measurement of the subcritical neutron multiplication factor for a fuel solution system.

  13. Determination of Fission Product Yields of 235U, 238U and 239Pu for Neutron Energies from 0.5 to 14.8 MeV

    Science.gov (United States)

    Gooden, Matthew; Arnold, Charles; Becker, John; Bhatia, Chitra; Bhike, Megha; Fowler, Malcolm; Howell, Calvin; Kelley, John; Stoyer, Mark; Tonchev, Anton; Tornow, Werner; Vieira, Dave; Wilhelmy, Jerry

    2014-03-01

    A joint TUNL-LANL-LLNL collaboration has been formed to study the issue of possible energy dependences for certain fission product isotopes. Work has been carried out at the TUNL 10 MV Tandem accelerator which produces nearly mono-energetic neutrons via either 2H(d,n)3He,3H(d,n)4He,or3H(p,n)3He reactions. Three dual fission ionization chambers dedicated to 235U, 238U and 239Pu thick target foils and thin monitor foils respectively, were exposed to the neutron beams. After irradiation, thick target foils were gamma counted over a period of 1-2 months and characteristic gamma rays from fission products were recorded using HPGe detectors at TUNL's low background counting area. Using the dual fission chambers, relative fission product yield were determined at a high precision of 2-3 % as well as absolute fission product yields at a lower precision of 5-6 %. Preliminary results will be presented for a number of fission product isotopes over the incident neutron energy range of 0.5 to 14.8 MeV.

  14. Energy Dependence of Neutron-Induced Fission Product Yields of 235U, 238U and 239Pu Between 0.5 and 14.8 MeV

    Science.gov (United States)

    Gooden, Matthew; Tornow, Werner; Tonchev, Anton; Vieira, Dave; Wilhelmy, Jerry; Arnold, Charles; Fowler, Malcolm; Stoyer, Mark

    2014-09-01

    Under a joint collaboration between TUNL-LANL-LLNL, a set of absolute fission product yield measurements have been performed. The energy dependence of a number of cumulative fission products between 0.5 and 14.8 MeV have been measured using quasi-monoenergetic neutron beams for three actinide targets, 235U, 238U and 239Pu, between 0.5 and 14.8 MeV. The FPYs were measured by a combination of activation utilizing specially designed dual-fission chambers and γ-ray counting. The dual-fission chambers are back-to-back ionization chambers encasing a target with thin deposits of the same target isotope in each chamber. This method allows for the direct measurement of the fission rate in the activation target with no reference to the fission cross-section, reducing uncertainties. γ-ray counting was performed on well-shield HPGe detectors over a period of 2 months per activation to properly identify fission products. Reported are absolute cumulative fission product yields for incident neutron energies of 0.5, 1.37, 2.4, 4.6 and 14.8 MeV.

  15. Synergistic anti-tumor effect of 17AAG with the PI3K/mTOR inhibitor NVP-BEZ235 on human melanoma.

    Science.gov (United States)

    Calero, R; Morchon, E; Martinez-Argudo, I; Serrano, R

    2017-10-10

    Drug resistance by MAPK signaling recovery or activation of alternative signaling pathways, such as PI3K/AKT/mTOR, is an important factor that limits the long-term efficacy of targeted therapies in melanoma patients. In the present study, we investigated the phospho-proteomic profile of RTKs and its correlation with downstream signaling pathways in human melanoma. We found that tyrosine kinase receptors expression correlated with the expression of pivotal downstream components of the RAS/RAF/MAPK and PI3K/AKT/mTOR pathways in melanoma cell lines and tumors. We also found high expression of HSP90 and the PI3K/AKT/mTOR pathway proteins, 4EBP1 and AKT compared with healthy tissue and this correlated with poor overall survival of melanoma patients. The combination of the HSP90 inhibitor 17AAG with the PI3K/mTOR inhibitor NVP-BEZ235 showed a synergistic activity decreasing melanoma cell growth, inducing apoptosis and targeting simultaneously the MAPK and PI3K/AKT/mTOR pathways. These results demonstrate that the combination of HSP90 and PI3K/mTOR inhibitors could be an effective therapeutic strategy that target the main survival pathways in melanoma and must be considered to overcome resistance to BRAF inhibitors in melanoma patients. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Laparoscopic Totally Extraperitoneal Groin Hernia Repair Using a Self-Gripping Mesh: Clinical Results of 235 Primary and Recurrent Groin Hernias.

    Science.gov (United States)

    Ozmen, John; Choi, Vincent; Hepburn, Kirsten; Hawkins, Will; Loi, Ken

    2015-11-01

    Compared with open surgery, laparoscopic groin hernia repair has been shown to significantly reduce postoperative pain. However, chronic pain remains a problem with the laparoscopic approach, affecting approximately 10% of patients. The purpose of this study was to evaluate clinical outcomes following the use of Parietex ProGrip™ (Covidien, Dublin, Ireland) self-gripping mesh during laparoscopic totally extraperitoneal groin hernia repair. Data were collected prospectively from 145 male and 15 female patients with 235 inguinal hernias. All patients underwent repair by the laparoscopic totally extraperitoneal approach using Parietex ProGrip mesh. During follow-up ranging from 5 to 24 months, complications, pain score, patient satisfaction, and recurrence were analyzed. All patients were discharged on the day of surgery or the next morning. There were no immediate complications or returns to the operating room. Delayed postoperative complications included minor bruising to the genital region (3 cases), hematoma/seroma (1 case), and wound infection (1 case). The mean follow-up was 15 months, at which time there were no reports of hernia recurrence and 99% of patients were satisfied with their hernia repair. One patient (0.63%) reported severe pain (numeric rating scale score of >7), and 4 patients (2.5%) reported intermittent mild pain on exertion. The results of this study suggest that the use of a self-gripping mesh during the laparoscopic totally extraperitoneal approach is a promising and effective technique for repairing both primary and recurrent inguinal hernias.

  17. Capsella bursa-pastoris extract as an eco-friendly inhibitor on the corrosion of Q235 carbon steels in 1 mol·L-1 hydrochloric acid☆

    Institute of Scientific and Technical Information of China (English)

    Qin Hu; Yubing Qiu; Guoan Zhang; Xingpeng Guo

    2015-01-01

    The corrosion inhibition effect of Capsel a bursa-pastoris extracts (CBE) for Q235 carbon steels in 1 mol·L−1 hy-drochloric acid solution was studied using electrochemical methods, environmental scanning electron microsco-py (SEM) and Raman microscopy analysis. The polarization plots indicate that CBE serves as an effective, mixed-type inhibitor. Linear polarization resistance shows that increasing CBE concentration and temperature results in increased inhibition efficiency. The highest inhibition efficiency can reach 97%when adding 60 mg·L−1 CBE, which is better than some reported plant extracts under the similar environment. The adsorption of CBE molecules is found to obey the Langmuir adsorption isotherm. Some thermodynamic and kinetic parameters for the adsorption process, such as the adsorption equilibrium constant (K), free energy of adsorption (ΔGads), ac-tivation energy of corrosion reaction (Ea) and the heat of adsorption (Q ads), are calculated and discussed. SEM and Raman microscopy analysis also demonstrate the formation of a CBE inhibition film on the metal surface.

  18. Effects of Fission Yield Data in the Calculation of Antineutrino Spectra for ^{235}U(n,fission) at Thermal and Fast Neutron Energies.

    Science.gov (United States)

    Sonzogni, A A; McCutchan, E A; Johnson, T D; Dimitriou, P

    2016-04-01

    Fission yields form an integral part of the prediction of antineutrino spectra generated by nuclear reactors, but little attention has been paid to the quality and reliability of the data used in current calculations. Following a critical review of the thermal and fast ENDF/B-VII.1 ^{235}U fission yields, deficiencies are identified and improved yields are obtained, based on corrections of erroneous yields, consistency between decay and fission yield data, and updated isomeric ratios. These corrected yields are used to calculate antineutrino spectra using the summation method. An anomalous value for the thermal fission yield of ^{86}Ge generates an excess of antineutrinos at 5-7 MeV, a feature which is no longer present when the corrected yields are used. Thermal spectra calculated with two distinct fission yield libraries (corrected ENDF/B and JEFF) differ by up to 6% in the 0-7 MeV energy window, allowing for a basic estimate of the uncertainty involved in the fission yield component of summation calculations. Finally, the fast neutron antineutrino spectrum is calculated, which at the moment can only be obtained with the summation method and may be relevant for short baseline reactor experiments using highly enriched uranium fuel.

  19. Unsuitability of 2,3,5-Triphenyl-2H-Tetrazolium chloride(TTC) as a viability assay for plant cells in suspention

    Energy Technology Data Exchange (ETDEWEB)

    Kebler, M.; Furusaki, S. [Department of Chemistry and Biotechnology Univ, Tokyo (Japan). Graduate School of Engineering

    1997-08-01

    The well-known viability assay with 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) is applied to plant cell suspensions. In this paper it is shown that parameters (pH, TTC concentration, incubation time) which are thought to b e only dependent on different cell lines are underlying at least two additional functions (age of the culture and shear stress). Each cell in a different state of activity requires a new set of the parameters mentioned above. Furthermore the time-dependent formazan production courses vary to such an extent that they cannot be used for viability determination. Therefore the usage of TTC as a viability test implies non negligible errors compared to the Evans` Blue staining method which does not involve cell metabolism. The values of the two different methods to determine the viability can differ by more than 50%. The data suggests abandoning the usage of TTC as a quantitative viability assay for plant cell suspensions. 22 refs., 7 figs., 1 tab.

  20. Osmotic induced stimulation of the reduction of the viability dye 2,3,5-triphenyltetrazolium chloride by maize roots and callus cultures.

    Science.gov (United States)

    Duncan, David R; Widholm, Jack M

    2004-04-01

    Live cells can reduce colorless 2,3,5-triphenyltetrazolium chloride (TTC) to a red insoluble compound, formazan. Maize (Zea mays) callus, when osmotically stressed by 0.53 mol/L mannitol, produced 7-times or more formazan than untreated control callus. This result was seen with all osmotica tested and could not be attributed to differences in TTC uptake rate or accumulation, increased respiration rate as measured by O2 uptake, or to de novo protein synthesis. Increased formazan production could be detected after 2.5 h of exposure to osmotic stress and leveled off after 48 h of exposure. The increased formazan production was only detected when callus was moved from high osmotic medium to low osmotic, TTC-containing medium. Abscisic acid increased TTC reduction only when added in combination with 0.53 mol/L mannitol. Incubation of maize seedling roots with 0.53 mol/L mannitol also increased formazan production as seen visually. Further studies are needed to determine the cause of the increased formazan production. These results show that TTC viability measurements must be carefully evaluated with appropriate controls to confirm their validity.

  1. Uranium ((234)U, (235)U and (238)U) contamination of the environment surrounding phosphogypsum waste heap in Wiślinka (northern Poland).

    Science.gov (United States)

    Olszewski, Grzegorz; Boryło, Alicja; Skwarzec, Bogdan

    2015-08-01

    The aim of this work was to determine the uranium concentration ((234)U, (235)U and (238)U) and values of the activity ratio (234)U/(238)U in soil samples collected near phosphogypsum waste heap in Wiślinka (northern Poland). On the basis of the studies it was found that the values of the (234)U/(238)U activity ratio in the analyzed soils collected in the vicinity of phosphogypsum dump in Wiślinka are in most cases close to one and indicate the phosphogypsum origin of the analyzed nuclides. The obtained results of uranium concentrations are however much lower than in previous years before closing of the phosphogypsum stockpile. After this process and covering the phosphogypsum stockpile in Wiślinka with sewage sludge, phosphogypsum particles are successfully immobilized. In the light of the results the use of phosphate fertilizers seems to be a major problem. Prolonged and heavy rains can cause leaching accumulated uranium isotopes in the phosphogypsum stockpile, which will be washed into the Martwa Wisła and on the fields in the immediate vicinity of this storage.

  2. Chlorine atom formation dynamics in the dissociation of halogenated pyridines after photoexcitation at 235 nm: A resonance enhanced multiphoton ionization-time of flight (REMPI-TOF) study

    Science.gov (United States)

    Srinivas, D.; Upadhyaya, Hari P.

    2016-06-01

    The photodissociation dynamics of halogen substituted pyridines, namely, 3-chloropyridine (ClPy) and 3-chloro-2,4,5,6-tetrafluoropyridine (ClFPy), has been studied around 235 nm by detecting chlorine atoms in their spin orbit states Cl(2P3/2) and Cl∗(2P1/2) using the REMPI-TOF technique. We have determined the translational energy distribution, the recoil anisotropy parameter, β, and the spin-orbit branching ratio, for chlorine atom elimination channels. The TOF profiles for Cl and Cl∗ are found to be independent of laser polarization suggesting a zero value for β, within the experimental uncertainties. For 3-chloropyridine, the average translational energies for Cl and Cl∗ elimination channels are determined to be 3.7 ± 1.0 and 7.0 ± 1.5 kcal/mol, respectively. Similarly, for 3-chloro-2,4,5,6-tetrafluoropyridine, the average translational energies for Cl and Cl∗ elimination channels are determined to be 8.0 ± 1.5 and 9.0 ± 1.5 kcal/mol, respectively. The theoretical calculation suggests that the fluorine substitution increases the possibility of cross over to the π-σ∗ state from the initially prepared π-π∗ state.

  3. Fission-product energy release for times following thermal-neutron fission of /sup 235/U between 2 and 14000 seconds

    Energy Technology Data Exchange (ETDEWEB)

    Dickens, J.K.; Emery, J.F.; Love, T.A.; McConnell, J.W.; Northcutt, K.J.; Peelle, R.W.; Weaver, H.

    1977-10-01

    Fission-product decay energy-releases rates were measured for thermal-neutron fission of /sup 235/U. Samples of mass 1 to 10 ..mu..g were irradiated for 1 to 100 sec by use of the fast pneumatic-tube facility at the Oak Ridge Research Reactor. The resulting beta- and gamma-ray emissions were counted for times-after-fission between 2 and 14,000 seconds. The data were obtained for beta and gamma rays separately as spectral distributions, N(E/sub ..gamma../) vs E/sub ..gamma../ and N(E/sub beta/) vs E/sub ..beta../. For the gamma-ray data the spectra were obtained by using a NaI detector, while for the beta-ray data the spectra were obtained by using an NE-110 detector with an anticoincidence mantle. The raw data were unfolded to provide spectral distributions of modest resolution. These were integrated over E/sub ..gamma../ and E/sub ..beta../ to provide total yield and energy integrals as a function of time after fission. Results are low compared to the present 1973 ANS Decay-heat standard. A complete description of the experimental apparatus and data-reduction techniques is presented. The final integral data are given in tabular and graphical form and are compared with published data. 41 figures, 13 tables.

  4. Evaluation of the neutron induced reactions on 235U from 2.25 keV up to 30 MeV

    Directory of Open Access Journals (Sweden)

    Trkov Andrej

    2017-01-01

    Full Text Available An evaluation of fast neutron induced reactions on 235U is performed in the 2.25 keV–30 MeV incident energy range with the code EMPIRE–3.2 Malta, combined with selected experimental data. The reaction model includes a dispersive optical model potential (RIPL 2408 that couples seven levels of the ground-state rotational band and a triple-humped fission barrier with absorption in the wells described within the optical model for fission. EGSM nuclear level densities are used in Hauser-Feshbach calculations of the compound-nuclear decay. The starting values for the model parameters are retrieved from the RIPL-3 data-base. Excellent agreement is achieved with available experimental data for neutron emission, neutron capture and fission, which gives confidence that the quantities for which there is no experimental information are also predicted accurately. In the fast neutron region of the evaluated file, the fission cross section is taken from Neutron Standards, and neutron capture includes fluctuations observed in recent experiments. Other channels are taken directly from model calculations. New evaluation is validated against ICSBEP criticality benchmarks with fast neutron spectra with excellent results.

  5. Contribution to the study of the interaction of slow neutrons with {sup 235}U using the time-of-flight method; Contribution a l'etude par la methode du temps de vol de l'interaction de neutrons lents avec l'U{sup 235}

    Energy Technology Data Exchange (ETDEWEB)

    Michaudon, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-05-15

    This study concerns the properties of the excited levels of uranium 236 obtained by interaction of slow neutron with uranium 235. The experiments have been carried out at the Saclay linear electron accelerator by use of the time of flight method. In the first part of this paper, we examine the technical and physical conditions which rule the experiments: compromise between resolution and counting rate, time dispersion due to the slowing down of the neutrons and crystalline binding effects. In a second part the experimental results i.e. total, fission and ternary fission cross sections are given. The third part deals with the analysis of these results: the resonance parameters determination ({tau}{sub n}, {tau}{sub {gamma}}, {tau}{sub f}), the study of their statistical distribution and of their correlations. We tried some classifications of the resonances according to their parameters and compared these classifications to each other and to other results. At least the evidence of a cross section correlation with a range smaller than 100 eV seems to be confirmed. (author) [French] Cette etude porte sur les proprietes des niveaux excites de l'Uranium-236 obtenus par l'interaction de neutrons lents avec le {sup 235}U. La technique experimentale est celle de la spectrometrie par temps de vol, les experiences ayant ete realisees aupres de l'accelerateur lineaire d'electrons de Saclay, Dans une premiere partie nous examinons les donnees techniques et physiques conditionnant les experiences: compromis entre resolution et taux de comptage, dispersion en temps due au ralentissement des neutrons, effet des liaisons cristallines. Dans une deuxieme partie sont exposes les resultats experimentaux: sections efficaces totales, de fission et de fission ternaire du {sup 235}U. Une troisieme partie porte sur l'analyse de ces resultats: determination des parametres ({tau}{sub n}, {tau}{sub {gamma}}, {tau}{sub f}), etude de leurs distributions statistiques et

  6. Efficiency of the low energy detection system for the measurement of {sup 235} U in lung of the Nuclear Regulatory Authority; Eficiencia del sistema de deteccion de baja energia para la medicion de {sup 235} U en pulmon de la Autoridad Regulatoria Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Spinella, M.R.; Krimer, M.; Gregori, B.N.; Rojo, A.M. [Autoridad Regulatoria Nuclear, Av. Del Libertador 8250 (C1429BNP), Buenos Aires (Argentina)]. e-mail: mspinell@cae.arn.gov.ar

    2006-07-01

    This work presents the results of the calibration process of the detection system of {sup 235} U in lung of the Nuclear Regulatory Authority. The phantom used in the calibration is the denominated Lawrence Livermore Realistic Phantom, provided of lungs and active nodules and of 4 thoracic covers that its simulate muscular tissue with thickness that vary between 1.638 and 3.871 cm. The spectra are acquired by four detecting of denominated LEGe ACTII Canberra marks, each one with an active area of 3800 mm{sup 2}, a diameter of 70 mm and a thickness of 20 mm, the sign is processed by a SYSTEM100 multichannel and the spectra are analyzed with the GENIE2K program. The detectors are suspended by mobile structures that allow to vary the position with regard to a horizontal stretcher that defines the measurement geometry. The whole system is located in the interior of an armored enclosure of 200 x 150 x 200 cm{sup 3} of steel of 15 cm thickness, inside recovered with layers of 0.5 cm lead and 0.05 cm cadmium. The total weight of the enclosure is 40 ton. For the described system the efficiency curves versus muscular thoracic tissue thickness (ETM) corresponding to the energy of 143.76, 163.358 and 185.72 keV of the {sup 235} U radioisotope were obtained. Its were also practiced displacements of those detectors of approximately 1 cm with respect to the reference position and its were analyzed the corresponding changes of magnitude in the efficiencies. The obtained variations oscillate, for vertical displacements, between 5% and 7.8% for the smallest value in ETM (1.638 cm) and between 4.2% to 6.7% for the ETM 3.871 cm. While for the practiced lateral displacements, the variations go from 4% to 15%. The detection limits corresponding to each energy and thickness were determined. The results showed for the photopeak of 185.72 keV, the more outstanding in the evaluations that saying limit it oscillates between 3.7 and 6.4 Bq {sup 235} U inside the considered thickness range

  7. 空间诱导蜡状芽孢杆菌LCT-BC25和LCT-BC235的蛋白质组学研究%Proteomics of space Bacillus cereus mutant starains LCT-BC25 and LCT-BC235

    Institute of Scientific and Technical Information of China (English)

    苏龙翔; 刘进文; 方向群; 李天志; 王俊峰; 郭英华; 常德; 徐国纲; 刘长庭

    2013-01-01

    Objective To study the proteomics of Bacillus cereus mutant strains LCT-BC25 and LCT-BC235 by detecting the effect of space environment on them. Methods Space Bacillus cereus mutant strains LCT-BC25 and LCT-BC235 and ground control strain LCT-BC244 were identified with isobaric tags for relative and absolute quantitation(iTRAQ) by mass spectrometry. The detected peptides were reassembled and their functions were analyzed. The proteins with a significantly different expression were selected. Results The majority of the 1 269 possible proteins identified in this study were related with the bacterial metabolism according to the cluster of orthologous groups (COG), gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG). The proteomic analysis showed that the protein levels were up-regulated in space 57 and 8 mutant strains and down-regulated in 77 and 73 ground control LCT-BC244 strain. Conclusion The effect of space environment on Bacillus cereus mutant trains is not directional. Bacillus cereus can adapt to the space environment by adjusting its own metablism. The highly expressed hemolytic enterotoxin protein can influence the health of astronauts.%  目的探索空间环境对蜡状芽孢杆菌的影响。方法采用同重同位素相对与绝对定量(isobaric tags for relativeand absolute quantitation,iTRAQ)技术对经空间诱变蜡状芽孢杆菌LCT-BC25和LCT-BC235以及地面对照株LCT-BC244进行蛋白质组质谱检测,对测得的肽段重新组装,对组装的蛋白进行功能注释分析,最终筛选具有明显表达差异的蛋白质。结果本研究共鉴定到1269个可能蛋白质,根据蛋白相邻类的聚簇(cluster of orthologous groups of proteins,COG)、基因本体论(gene ontology,GO)、京都基因与基因组百科全书(kyoto encyclopedia of genes and genomes,KEGG)对这些蛋白质进行分类分析发现,大多数鉴定到的蛋白与细菌代谢相关。比较蛋白质组学结果表明,空间诱变株LCT-BC25

  8. Analysis of risk factors of bone metastases from prostate cancer-single center 235 case control study%前列腺癌骨转移危险因素分析-单中心235例病例对照研究

    Institute of Scientific and Technical Information of China (English)

    安恒庆; 郑路; 李佳; 王峰; 张立东; 王玉杰

    2015-01-01

    Objective To explore the risk factors of bone metastasis of prostate cancer.Methods On SPECT bone scan is the gold standard for the diagnosis of prostate carcinoma with bone metastasis.By u-sing the method of comparative study of single center we analyzed 235 prostate cancer patients Age, Gleson score,Serum prostate specific antigen,Serumfree prostate specific antigen and Serum F/T level which is correlation with bone metastasis of prostate cancer.Results 235 cases of prostate cancer patients with bone metastasis occurred in 101 cases and 134 cases did not have bone metastasis.By univariate analy-sis,bone metastasis of prostate cancer was correlated with age,Gleason score,TPSA,FPSA,F/T (P 20 ng/mL group of bone metastasis in patients with significantly more than the other groups,there were significant differences (P 20 ng/mL will increase the risk of patients with bone metastasis.%目的:初步探讨前列腺癌骨转移的危险因素。方法以 SPECT 全身骨显像为诊断前列腺癌骨转移的金标准,采用单中心对照研究的方法分析235例前列腺癌患者的年龄、Gleson 评分、血清前列腺特异性抗原(TP-SA)、血清游离前列腺特异性抗原(FPSA)及血清 F/T 值与前列腺癌骨转移的相关性。结果235例前列腺癌患者中101例发生骨转移,134例未发生骨转移,单因素分析显示年龄、Gleason 评分、TPSA、FPSA、F/T 值与前列腺癌骨转移密切相关(P <0.05),多因素 Logistic 回归分析显示:年龄(OR =1.08,P <0.05)、Gleason 评分(OR =2.90,P <0.05)、TPSA 值(OR =1.05,P <0.05)是其主要的独立危险因素。分层研究显示;在年龄≥70岁、Gleason 评分≥7分、TPSA>20ng/ml 组中骨转移的患者明显多于其他组,差异均具有统计学意义(P <0.05)。结论年龄、Gleason 评分及 TPSA 是前列腺癌骨转移的主要危险因素,年龄≥70岁、Gleason 评分≥7

  9. 基于A/H外推法的低碳钢Q235真实应力应变关系研究%Research on True Stress-strain Curves of Mild Steel Q235 Based on A/H Extrapolation

    Institute of Scientific and Technical Information of China (English)

    周鹏; 张培彦

    2013-01-01

    通过新单轴压缩实验并结合A/H外推法获得低碳钢Q235真实应力-应变曲线.所得真实应力-应变曲线与理论曲线非常一致,明显出现3个阶段:弹性阶段、屈服阶段和强化阶段.摩擦力对弹性阶段压缩试件的本构关系影响非常小,而随着塑性变形增大,摩擦力对试件本构关系影响变大,从而导致名义应力-应变曲线高于真实应力-应变曲线.

  10. Experimental research and finite-element analysis of thermoplastic effect during tensile tests of Q235 steel%Q235钢拉伸过程热塑性效应试验研究及有限元分析

    Institute of Scientific and Technical Information of China (English)

    王为清; 杨立; 范春利; 吕事桂; 石宏臣

    2013-01-01

      在分析材料热弹塑性效应的基础上,用红外热像仪对Q235钢试件在拉伸过程中的表面温度进行测量,获得了不同应变率条件下试件表面温度分布及随时间的变化;确定了Q235钢全程拉伸真应力-真应变曲线,以此作为材料本构关系对拉伸过程中的热塑性效应进行数值模拟,讨论了应变率、系数、对流换热系数等对试件表面温度的影响。结果表明,应变率越大,变形过程中的热损失越小,从而由塑性变形产生的温升也越高;由拉伸过程中颈缩区域的温升最高、颈缩区域向试件两端温升逐渐降低的分布特点,则可说明在同一时间内塑性变形越大、越集中的区域,其温升也越大。文中的数值计算结果表明,用现有的有限元软件对材料热塑性效应进行数值分析不失为一种有效的研究方法。%  Based on the analysis of thermo-elastic-plastic effect, the surface temperature of Q235 steel during tensile tests was measured by using an infrared camera. Both the surface temperature field and it versus time for different strain rate were obtained. The true stress and true strain curve was determined, and this curve was used as the constitutive equations of Q235 steel. A numerical procedure was devised to model the thermoplastic effect during the tensile tests by using ANSYS software, and the influence of the strain rate, coefficient and heat-transfer coefficient on the surface temperature were studied. The results show that the heat loss during deformation process will be smaller as the strain rate increase, and the temperature increase on the specimen surface generated by the plastic deformation will be higher. The temperature rise at the middle of specimen near the necking area is maximum, while it declines towards the end of specimen from the necking area. It is concluded that the larger and more concentrative plastic deformation of specimen happens at the

  11. Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways

    Directory of Open Access Journals (Sweden)

    Chen J

    2014-07-01

    Full Text Available Jiezhong Chen,1,2 Renfu Shao,3 Li Li,4 Zhi Ping Xu,4 Wenyi Gu4 1School of Biomedical Sciences, University of Queensland, St Lucia, Queensland, 2Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, New South Wales, 3GeneCology Research Centre, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Maroochydore, Queensland, 4Australian Institute of Bioengineering and Nanotechnology, University of Queensland, St Lucia, Queensland, Australia Abstract: Colon cancer is the third most common cancer and the third largest cause of cancer-related death. Fluorouracil (5-FU is the front-line chemotherapeutic agent for colon cancer. However, its response rate is less than 60%, even in combination with other chemotherapeutic agents. The side effects of 5-FU also limit its application. Nanoparticles have been used to deliver 5-FU, to increase its effectiveness and reduce side effects. Another common approach for colon cancer treatment is targeted therapy against the phosphoinositide 3-kinase (PI3K/protein kinase B (Akt pathway. A recently-invented inhibitor of this pathway, BEZ-235, has been tested in several clinical trials and has shown effectiveness and low side effects. Thus, it is a very promising drug for colon cancer treatment. The combination of these two drugs, especially nanoparticle-packed 5-FU and BEZ-235, has not been studied. In the present study, we demonstrated that nanoparticles of layered double hydroxide (LDH loaded with 5-FU were more effective than a free drug at inhibiting colon cancer cell growth, and that a combination treatment with BEZ-235 further increased the sensitivity of colon cancer cells to the treatment of LDH-packed 5-FU (LDH-5-FU. BEZ-235 alone can decrease colon cancer HCT-116 cell viability to 46% of the control, and the addition of LDH-5-FU produced a greater effect, reducing cell survival to 8% of the control. Our data indicate that the combination therapy of

  12. Research of Curving Test on Racket Made of Cold-drawing Q235 Tube after Carbonized in “603” Liquid%Q235钢管“603”渗碳后的变形试验研究

    Institute of Scientific and Technical Information of China (English)

    陆秋君; 王均捷; 张世洪

    2001-01-01

    为解决普通羽毛球拍杆因强度低容易出现折断的现象,经过分析研究和大量试验,采用“603”液体渗碳工艺后直接淬火,再180℃回火的热处理工艺,可使Q235冷拉管制成的羽毛球拍杆具有较好的性能,使用中既不弯曲又不折断。然而存在变形量不同的现象,这是由于渗碳不均匀造成,出现球拍杆的性能有高有低。在实际生产中应及时补充“603”液体,保证炉温和碳浓度均匀一致,以提高羽毛球拍杆性能质量。%In order to resolve breaking easily of usual badminton racketbecause of low intensity the following pursuit is done. According to research and a great quantity tests of heat treatment tests, carbonized in “603” liquid and then tempered in 180 centigrade, is applied to racket made of cold-drawing Q235 steel tube. By such heat treatment, racket has better properties, and doesn't curve and break in using. But phenomenon of different distortion exists. Different carbonization consistence bring about this circumstance and made property of badminton racket high or low。In actual producing “603” liquid have to be supplied in time to ensure furnace temperature and carbon deepness equality and coherence and to improve badminton racket performance and quality.

  13. Determination of uranium isotopes ({sup 235}U, {sup 238}U) and trace elements (Cd, Pb, Cu and As) in bottled drinking water by Icp-SFMS; Determinacion de isotopos de uranio ({sup 235}U, {sup 238}U) y elementos traza (Cd, Pb, Cu y As) en agua embotellada para beber por ICP-SFMS

    Energy Technology Data Exchange (ETDEWEB)

    Lara A, N.; Hernandez M, H.; Romero G, E. T.; Kuri de la C, A.; Perez B, M. A., E-mail: nancy.lara@inin.gob.mx [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico)

    2016-09-15

    In the present work we propose an optimized method for the quantification of uranium isotopes ({sup 235}U, 2{sup 38}U) and the elements Cd, Pb, Cu and As in bottled water for drinking at trace levels of concentration. Based on the multi-element detection capability, the high sensitivity and resolution that the Mass Spectrometry with Magnetic Sector with Inductively Coupled Plasma Source (Icp-SFMS) technique offers; the high, medium and low resolution analysis conditions for the elements under study were established and optimized using and Element 2/Xr equipment and the 23 multi-elemental Certified Reference Material (CRM). The analysis method was validated using the standard reference material Nist 1643d and CRM mono-elemental s as external standards for the quantification of the analytes. Samples, targets and CRM were acidified with 2% of HNO{sub 3} and analyzed without pretreatment under the established analysis conditions. The results obtained show concentrations of {sup 235}U, {sup 238}U, {sup 111}Cd, {sup 208}Pb, {sup 63}Cu and {sup 75}As in the range of μg L{sup -1}, the linearity obtained from the calibration curves for each element has correlation coefficients < 0.99 in all cases, the accuracy of the method in terms of percent relative standard deviation (RSD %) was less than 5%, the mean recovery rate of Nist 1643d ranged from 96.46% to 101.12%. The optimization of the method guarantees the stability and calibration of the equipment throughout the analysis, as well as the ability to resolve interferences. In conclusion, the method proposed using Icp-SFMS offers the advantages of being fast and simple for the multi-elemental analysis in water at trace levels, with low limits of quantification and detection, with good linearity, accuracy, precision and reproducibility to a degree of reliability of 95%. (Author)

  14. [Detection method for the ability of hemp (Cannabis sativa L.) seed germination by the use of 2,3,5-triphenyl-2H-tetrazolium chloride (TTC)].

    Science.gov (United States)

    Ogata, Jun; Kikura-Hanajiri, Ruri; Yoshimatsu, Kayo; Kiuchi, Fumiyuki; Goda, Yukihiro

    2008-11-01

    Cannabis plants show a high Delta9-tetrahydrocannabinol content and are used as a psychoactive drug. Therefore the cultivation of hemp and its possession are prohibited by law in Japan. Meanwhile, Cannabis seeds have been used as a component of shichimi-togarashi (a Japanese spice), bird feed, or a crude drug (mashinin). To exclude the possibility of germination, it is officially noticed that hemp seeds must be killed. However, the number of violators has increased in recent years. To judge the ability of seed germination, a germination test is performed. However, the test requires several days and thus has not been used for on-site inspection. In this study, we developed a rapid detection method to determine the ability of Cannabis seeds to germinate using 2,3,5-triphenyl-2H-tetrazolium chloride (TTC). The principle of the assay is as follows. The endogenous respiratory enzymes in hemp seeds convert added colorless TTC into red 1,3,5-triphenylformazan. Consequently, a living embryo is stained red, while red does not appear in the dead seeds. The reaction was active over a pH range of 8.0-9.0, and the optimum activity was found from 40 to 50 degrees C. Under the optimum conditions, we were able to determine the ability of seeds to germinate based on the presence of color within 20 min. Since this method is rapid and simple, it is applicable to on-site inspections. In addition, it could be used as an alternative technique to the germination test, because erroneous decisions is cannot occur under the assay principle.

  15. Energy dependence of fission product yields from 235U, 238U, and 239Pu with monoenergetic neutrons between thermal and 14.8 MeV

    Science.gov (United States)

    Gooden, Matthew; Arnold, Charles; Bhike, Megha; Bredeweg, Todd; Fowler, Malcolm; Krishichayan; Tonchev, Anton; Tornow, Werner; Stoyer, Mark; Vieira, David; Wilhelmy, Jerry

    2017-09-01

    Under a joint collaboration between TUNL-LANL-LLNL, a set of absolute fission product yield measurements has been performed. The energy dependence of a number of cumulative fission product yields (FPY) have been measured using quasi-monoenergetic neutron beams for three actinide targets, 235U, 238U and 239Pu, between 0.5 and 14.8 MeV. The FPYs were measured by a combination of fission counting using specially designed dual-fission chambers and γ-ray counting. Each dual-fission chamber is a back-to-back ionization chamber encasing an activation target in the center with thin deposits of the same target isotope in each chamber. This method allows for the direct measurement of the total number of fissions in the activation target with no reference to the fission cross-section, thus reducing uncertainties. γ-ray counting of the activation target was performed on well-shielded HPGe detectors over a period of two months post irradiation to properly identify fission products. Reported are absolute cumulative fission product yields for incident neutron energies of 0.5, 1.37, 2.4, 3.6, 4.6, 5.5, 7.5, 8.9 and 14.8 MeV. Preliminary results from thermal irradiations at the MIT research reactor will also be presented and compared to present data and evaluations. This work was performed under the auspices of the U.S. Department of Energy by Los Alamos National Security, LLC under contract DE-AC52-06NA25396, Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344 and by Duke University and Triangle Universities Nuclear Laboratory through NNSA Stewardship Science Academic Alliance grant No. DE-FG52-09NA29465, DE-FG52-09NA29448 and Office of Nuclear Physics Grant No. DE-FG02-97ER41033.

  16. Measurement of the neutron capture cross section of the fissile isotope $^{235}$U with the CERN n_TOF Total Absorption Calorimeter and a fission tagging based on micromegas detectors

    CERN Document Server

    Mendoza, E; Cano-Ott, D; Guerrero, C; Berthoumieux, E; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Becvár, F; Belloni, F; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviani, M; Calviño, F; Carrapiço, C; Cerutti, F; Chiaveri, E; Chin, M; Colonna, N; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gunsing, F; Gurusamy, P; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kawano, T; Kivel, N; Koehler, P; Kokkoris, M; Korschinek, G; Krticka, M; Kroll, J; Langer, C; Lampoudis, C; Leal-Cidoncha, E; Lederer, C; Leeb, H; Leong, L S; Losito, R; Manousos, A; Marganiec, J; Martínez, T; Mastinu, P F; Mastromarco, M; Massimi, C; Meaze, M; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondelaers, W; Paradela, C; Pavlik, A; Perkowski, J; Pignatari, M; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Roman, F; Rubbia, C; Sarmento, R; Schillebeeckx, P; Schmidt, S; Schumann, D; Stetcu, I; Sabaté, M; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T; Zugec, P

    2014-01-01

    Actual and future nuclear technologies require more accurate nuclear data on the (n, $\\gamma$) cross sections and $\\alpha$-ratios of fissile isotopes. Their measurement presents several difficulties, mainly related to the strong fission $\\gamma$-ray background competing with the weaker $\\gamma$-ray cascades used as the experimental signature of the (n, $\\gamma$) process. A specific setup has been used at the CERN n_TOF facility in 2012 for the measurement of the (n,$\\gamma$ ) cross section and $\\alpha$- ratios of fissile isotopes and used for the case of the $^{235}$U isotope. The setup consists in a set of micromegas fission detectors surrounding $^{235}$U samples and placed inside the segmented BaF$_2$ Total Absorption Calorimeter.

  17. Measurement of the Neutron Capture Cross Section of the Fissile Isotope 235U with the CERN n_TOF Total Absorption Calorimeter and a Fission Tagging Based on Micromegas Detectors

    CERN Document Server

    Balibrea, J; Cano-Ott, D; Guerrero, C; Berthoumieux, E; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Bécares, V; Bečvář, F; Belloni, F; Billowes, J; Boccone, V; Bosnar, D; Brugger, M; Calviani, M; Calviño, F; Carrapiço, C; Cerutti, F; Chiaveri, E; Chin, M; Colonna, N; Cortés, G; Cortés-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Dzysiuk, N; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; García, A R; Giubrone, G; Gómez-Hornillos, M B; Gonçalves, I F; González-Romero, E; Griesmayer, E; Gunsing, F; Gurusamy, P; Jenkins, D G; Jericha, E; Kadi, Y; Käppeler, F; Karadimos, D; Kawano, T; Kivel, N; Koehler, P; Kokkoris, M; Korschinek, G; Krtička, M; Kroll, J; Langer, C; Lampoudis, C; Lederer, C; Leeb, H; Leong, L S; Losito, R; Manousos, A; Marganiec, J; Martínez, T; Mastinu, P F; Mastromarco, M; Massimi, C; Meaze, M; Mengoni, A; Milazzo, P M; Mingrone, F; Mirea, M; Mondelaers, W; Paradela, C; Pavlik, A; Perkowski, J; Pignatari, M; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Roman, F; Rubbia, C; Sarmento, R; Schillebeeckx, P; Schmidt, S; Schumann, D; Stetcu, I; Sabaté, M; Tagliente, G; Tain, J L; Tarrío, D; Tassan-Got, L; Tsinganis, A; Valenta, S; Vannini, G; Variale, V; Vaz, P; Ventura, A; Versaci, R; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiß, C; Wright, T J; Žugec, P

    Current and future nuclear technologies require more accurate nuclear data on (n,γ) cross sections and the α-ratios of fissile isotopes. Their measurement presents several difficulties, mainly related to the strong fission γ-ray background competing with the weaker γ-ray cascades used as the experimental signature of the (n,γ) process. A specific setup was used at the CERN n_TOF facility in 2012 for the measurement of the (n,γ) cross section and α-ratios of fissile isotopes and used for the case of the 235U isotope. The setup consists of a set of micromegas fission detectors surrounding the 235U samples all placed inside a segmented BaF2 Total Absorption Calorimeter.

  18. Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11.

    Science.gov (United States)

    Bennett, Eric P; Chen, Ya-Wen; Schwientek, Tilo; Mandel, Ulla; Schjoldager, Katrine ter-Borch Gram; Cohen, Stephen M; Clausen, Henrik

    2010-05-01

    The Drosophila l(2)35Aa gene encodes a UDP-N-acetylgalactosamine: Polypeptide N-acetylgalactosaminyltransferase, essential for embryogenesis and development (J. Biol. Chem. 277, 22623-22638; J. Biol. Chem. 277, 22616-22). l(2)35Aa, also known as pgant35A, is a member of a large evolutionarily conserved family of genes encoding polypeptide GalNAc-transferases. Phylogenetic and functional analyses have proposed that subfamilies of orthologous GalNAc-transferase genes are conserved in species, suggesting that they serve distinct functions in vivo. Based on sequence alignments, pgant35A and human GALNT11 are thought to belong to a distinct subfamily. Recent in vitro studies have shown that pgant35A and pgant7, encoding enzymes from different subfamilies, prefer different acceptor substrates, whereas the orthologous pgant35A and human GALNT11 gene products possess, 1) conserved substrate preferences and 2) similar acceptor site preferences in vitro. In line with the in vitro pgant7 studies, we show that l(2)35Aa lethality is not rescued by ectopic pgant7 expression. Remarkably and in contrast to this observation, the human pgant35A ortholog, GALNT11, was shown not to support rescue of the l(2)35Aa lethality. By use of genetic "domain swapping" experiments we demonstrate, that lack of rescue was not caused by inappropriate sub-cellular targeting of functionally active GalNAc-T11. Collectively our results show, that fly embryogenesis specifically requires functional pgant35A, and that the presence of this gene product during fly embryogenesis is functionally distinct from other Drosophila GalNAc-transferase isoforms and from the proposed human ortholog GALNT11.

  19. Proceedings of the NEANDC/NEACRP specialists meeting on fast neutron fission cross sections of U-233, U-235, U-238, and Pu-239, June 28--30, 1976, at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Poenitz, W P; Guenther, P T

    1976-01-01

    Data files of all available data of absolute cross section measurements of U-233, U-235, U-238 and Pu-239, and of the ratios of U-233, U-238, and Pu-239 to U-235 were assembled at Argonne National Laboratory for use by the two Working Groups. The data files of absolute cross sections included also data measured relative to one of the standard cross sections H(n,n), Li-6(n,..cap alpha..), and B-10(n,..cap alpha..), and the ratio data files included ratios derived from absolute values which were measured in an identical type of experiment by the same group of experimenters. The subject files (e.g., U-235-Absolute, or U-238/U-235-Ratio, etc.) consisted of ''Sets.'' These sets contained the data from one experimental group which may have been published at different times. The assembling of the files was started with an extract from the CSISRS data files of the National Neutron Cross Section Center at the Brookhaven National Laboratory. Ratios were derived from quoted consistent sets of absolute cross sections, or from data which were actually measured as ratios but quoted as absolute values. The latter type of data was eliminated from the data files on absolute values. The files were improved by an extensive search for errors and data missing on the original CSISRS files at the time the extract was made. Other additions to the present subject files came from presentations made at this meeting and are described in the proceedings.

  20. Absorption by XeCl* excimer molecules of their own emission of the B-X transition (λ = 308 nm) in a dense Ar-Xe-CCl4 medium upon pumping by fast electrons and uranium-235 fission fragments

    Science.gov (United States)

    Mis'kevich, A. I.; Dyuzhov, Yu. A.; Suvorov, A. A.

    2016-08-01

    Luminescence of dense Ar-Xe-CCl4 gas mixtures with a low CCl4 content upon pumping by fast electrons and uranium-235 fission fragments is studied by spectroscopic methods. It is found that, in a cell with a resonator tuned to the B-X transition of the XeCl* molecule (λ = 308 nm), the D-state population of the XeCl* excimer molecule (the D-X transition, λ = 235 nm) depends on the B-state population and increases by many times with increasing B-state population of the XeCl* molecule. The stimulated absorption coefficient k = 1.2 × 10-16 of B-X transition emission of the XeCl* molecule (λmax = 308 nm), which leads to population of the D-state of this molecule, and the coefficient of amplification μ = 2.5 × 10-4 cm-1 of B-X transition emission of the Xe Cl* molecule (λ = 308 nm) are measured upon pumping by uranium- 235 fission fragments with the specific energy input into the gas medium of ~60 mJ/cm3 and a specific power of energy input of about 240 W/cm3.

  1. Characterization of bauxite residue (red mud) for (235)U, (238)U, (232)Th and (40)K using neutron activation analysis and the radiation dose levels as modeled by MCNP.

    Science.gov (United States)

    Landsberger, S; Sharp, A; Wang, S; Pontikes, Y; Tkaczyk, A H

    2017-07-01

    This study employs thermal and epithermal neutron activation analysis (NAA) to quantitatively and specifically determine absorption dose rates to various body parts from uranium, thorium and potassium. Specifically, a case study of bauxite residue (red mud) from an industrial facility was used to demonstrate the feasibility of the NAA approach for radiological safety assessment, using small sample sizes to ascertain the activities of (235)U, (238)U, (232)Th and (40)K. This proof-of-concept was shown to produce reliable results and a similar approach could be used for quantitative assessment of other samples with possible radiological significance. (238)U and (232)Th were determined by epithermal and thermal neutron activation analysis, respectively. (235)U was determined based on the known isotopic ratio of (238)U/(235)U. (40)K was also determined using epithermal neutron activation analysis to measure total potassium content and then subtracting its isotopic contribution. Furthermore, the work demonstrates the application of Monte Carlo Neutral-Particle (MCNP) simulations to estimate the radiation dose from large quantities of red mud, to assure the safety of humans and the surrounding environment. Phantoms were employed to observe the dose distribution throughout the human body demonstrating radiation effects on each individual organ. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Production of {sup 234,235}Np and {sup 236}Pu in bombardment of {sup 236}U with protons in the energy range from 17 to 40 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, J.; Helariutta, K. [Univ. of Helsinki, Lab. of Radiochemistry, Dept. of Chemistry, Univ. of Helsinki (Finland); Gromova, E.A.; Jakovlev, V.A. [V. G. Khlopin Radium Inst., Lab. of Nuclear Reactions and Nuclear Medicine, St. Petersburg (Russian Federation); Trzaska, W.H.; Huikari, J.; Kolhinen, V.S.; Rinta-Antila, S. [Univ. of Jyvaeskylae, Accelerator Lab., Dept. of Physics, Jyvaeskylae (Finland)

    2005-07-01

    The production of {sup 235}Np and {sup 236}Pu by the reactions {sup 236}U(p, 2n){sup 235}Np and {sup 236}U(p, n{beta}{sup -}){sup 236}Pu using the K-130 cyclotron of the University of Jyvaeskylaewas investigated. The cross sections for the reactions were determined. Thick-target yield curves were derived based on the cross sections. The results are discussed and compared with previous data on other reactions leading to the formation of the same end products. The thick-target yield of {sup 235}Np in the {sup 236}U(p, 2n) reaction is about 50 percent higher than the yield obtained in the {sup 238}U(p, 4n) reaction leading to this nuclide at comparable particle energies. The purity of {sup 236}Pu produced in the {sup 236}U(p, n{beta}{sup -}) reaction is more than ten times better than for earlier known as the purest reaction {sup 237}Np(p, 2n + pn{beta}{sup -}){sup 236}Pu. (orig.)

  3. Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 expression and inhibition of Mcl-1 protein stability.

    Directory of Open Access Journals (Sweden)

    Bo Ram Seo

    Full Text Available The PI3K/Akt and mTOR signaling pathways are important for cell survival and growth, and they are highly activated in cancer cells compared with normal cells. Therefore, these signaling pathways are targets for inducing cancer cell death. The dual PI3K/Akt and mTOR inhibitor NVP-BEZ235 completely inhibited both signaling pathways. However, NVP-BEZ235 had no effect on cell death in human renal carcinoma Caki cells. We tested whether combined treatment with natural compounds and NVP-BEZ235 could induce cell death. Among several chemopreventive agents, curcumin, a natural biologically active compound that is extracted from the rhizomes of Curcuma species, markedly induced apoptosis in NVP-BEZ235-treated cells. Co-treatment with curcumin and NVP-BEZ235 led to the down-regulation of Mcl-1 protein expression but not mRNA expression. Ectopic expression of Mcl-1 completely inhibited curcumin plus NVP-NEZ235-induced apoptosis. Furthermore, the down-regulation of Bcl-2 was involved in curcumin plus NVP-BEZ235-induced apoptosis. Curcumin or NVP-BEZ235 alone did not change Bcl-2 mRNA or protein expression, but co-treatment reduced Bcl-2 mRNA and protein expression. Combined treatment with NVP-BEZ235 and curcumin reduced Bcl-2 expression in wild-type p53 HCT116 human colon carcinoma cells but not p53-null HCT116 cells. Moreover, Bcl-2 expression was completely reversed by treatment with pifithrin-α, a p53-specific inhibitor. Ectopic expression of Bcl-2 also inhibited apoptosis in NVP-BE235 plus curcumin-treated cells. In contrast, NVP-BEZ235 combined with curcumin did not have a synergistic effect on normal human skin fibroblasts and normal human mesangial cells. Taken together, combined treatment with NVP-BEZ235 and curcumin induces apoptosis through p53-dependent Bcl-2 mRNA down-regulation at the transcriptional level and Mcl-1 protein down-regulation at the post-transcriptional level.

  4. 基于Gurson-JC模型的铝合金6061T6和低碳钢Q235力学性能表征%Characterization of mechanical properties of aluminium alloy 6061T6 and low carbon steel Q235 based on Gurson-JC model

    Institute of Scientific and Technical Information of China (English)

    陆善彬; 周璐瑶; 郭赛

    2014-01-01

    T he basic sheet material fracture testing under different stress triaxialities and strain rates is carried out on specimens of low carbon steel Q 235 and aluminium alloy 6061T6 ,and the mechanical properties of these two materials under different working conditions are obtained .Six parameters of Gurson model are optimized by using LS-OPT software .This optimization method improves the effi-ciency in parameters determination and makes Gurson model applicable under a certain range of stress triaxiality .However ,Gurson model is incapable of predicting shear fracture under low stress triaxiali-ty .So an improved Gurson model with the strain failure criterion of Johnson-Cook model under low stress triaxiality is used to overcome this weakness under the shear working condition .Through the simulation and comparison of two materials under different stress triaxialities and strain rates by Gur-son model and Johnson-Cook model ,the relevant parameters of Gurson-JC model of the two materials are determined so as to satisfy the accuracy requirement under a wider range of stress triaxiality and strain rate .%文章对低碳钢Q235和铝合金6061T6试样在不同应力三轴度下进行拉伸试验,得到2种材料在不同工况下的力学性能。采用LS-OPT软件对Gurson模型相关参数进行优化,该优化方法既可以提高参数确定的效率,同时可以使Gurson模型在一定应力三轴度范围内适用。但Gurson模型不能准确预测在低应力三轴度下的失效,所以在低应力三轴度下引入Johnson-Cook模型的应变失效标准,以弥补剪切工况下的不足。通过比较Gurson模型和Johnson-Cook模型对2种材料在不同应力三轴度下的仿真结果,确定2种材料的Gurson-JC模型相关参数,以满足在较大范围内的应力三轴度下的仿真精准度。

  5. Characteristics of Epstein-Barr virus-associated gastric cancer: A study of 235 cases at a comprehensive cancer center in U.S.A

    Directory of Open Access Journals (Sweden)

    Yu Yingyan

    2009-02-01

    Full Text Available Abstract Background Epstein-Barr virus (EBV has been shown to be associated with gastric cancer. However, inconsistent findings have been reported regarding the distribution of EBV infected cells (in normal gastric epithelium vs. intestinal metaplastic cells vs. in neoplastic cells and the characteristics of EBV-associated gastric cancer. Lymph node positive EBV-associated gastric cancer has not been systematically studied. The aims of this study were to evaluate EBV-associated gastric cancer, to assess the distribution of EBV infected cells including all positive lymph nodes, and to define the characteristics of EBV-associated gastric cancer. Design The study included primary gastric cancer patients who underwent surgical resection with no preoperative treatment at M.D. Anderson Cancer Center between 1987 and 2006. Formalin-fixed paraffin-embedded tissue from these resection specimens were assessed for EBV by in situ hybridization, the gold standard for EBV detection in tissue. EBV status was analyzed along with clinicopathologic parameters including age, gender, tumor type, lymph node status, and pathologic stage of the tumor. Results Among 235 patients, 12 had intranuclear expression of EBV. EBV staining was seen only in tumor cells and no detectable EBV was observed in normal gastric mucosa, intestinal metaplasia or stromal cells. Eight of 12 patients with EBV-associated gastric cancer had regional lymph node metastasis. Of note, metastatic tumor cells in all of the involved lymph nodes of these 8 cases contained EBV. The epidemiologic data showed 11 of the 12 patients with EBV-associated gastric cancer were men, ranging in age from 54 to 78 years (mean age, 60 years; median age, 62.1 years. The age distribution for non-EBV associated gastric cancer patients ranged from 21 to 93 years (mean age, 67 years; median age, 66.4 years. Conclusion Our study demonstrated that EBV is present exclusively in gastric cancer cells. The detection of EBV in

  6. Distinct 238U/235U ratios and REE patterns in plutonic and volcanic angrites: Geochronologic implications and evidence for U isotope fractionation during magmatic processes

    Science.gov (United States)

    Tissot, François L. H.; Dauphas, Nicolas; Grove, Timothy L.

    2017-09-01

    Angrites are differentiated meteorites that formed between 4 and 11 Myr after Solar System formation, when several short-lived nuclides (e.g., 26Al-26Mg, 53Mn-53Cr, 182Hf-182W) were still alive. As such, angrites are prime anchors to tie the relative chronology inferred from these short-lived radionuclides to the absolute Pb-Pb clock. The discovery of variable U isotopic composition (at the sub-permil level) calls for a revision of Pb-Pb ages calculated using an ;assumed; constant 238U/235U ratio (i.e., Pb-Pb ages published before 2009-2010). In this paper, we report high-precision U isotope measurement for six angrite samples (NWA 4590, NWA 4801, NWA 6291, Angra dos Reis, D'Orbigny, and Sahara 99555) using multi-collector inductively coupled plasma mass-spectrometry and the IRMM-3636 U double-spike. The age corrections range from -0.17 to -1.20 Myr depending on the samples. After correction, concordance between the revised Pb-Pb and Hf-W and Mn-Cr ages of plutonic and quenched angrites is good, and the initial (53Mn/55Mn)0 ratio in the Early Solar System (ESS) is recalculated as being (7 ± 1) × 10-6 at the formation of the Solar System (the error bar incorporates uncertainty in the absolute age of Calcium, Aluminum-rich inclusions - CAIs). An uncertainty remains as to whether the Al-Mg and Pb-Pb systems agree in large part due to uncertainties in the Pb-Pb age of CAIs. A systematic difference is found in the U isotopic compositions of quenched and plutonic angrites of +0.17‰. A difference is also found between the rare earth element (REE) patterns of these two angrite subgroups. The δ238U values are consistent with fractionation during magmatic evolution of the angrite parent melt. Stable U isotope fractionation due to a change in the coordination environment of U during incorporation into pyroxene could be responsible for such a fractionation. In this context, Pb-Pb ages derived from pyroxenes fraction should be corrected using the U isotope composition

  7. ZPR-3 Assembly 6F : A spherical assembly of highly enriched uranium, depleted uranium, aluminum and steel with an average {sup 235}U enrichment of 47 atom %.

    Energy Technology Data Exchange (ETDEWEB)

    Lell, R. M.; McKnight, R. D; Schaefer, R. W.; Nuclear Engineering Division

    2010-09-30

    Over a period of 30 years, more than a hundred Zero Power Reactor (ZPR) critical assemblies were constructed at Argonne National Laboratory. The ZPR facilities, ZPR-3, ZPR-6, ZPR-9 and ZPPR, were all fast critical assembly facilities. The ZPR critical assemblies were constructed to support fast reactor development, but data from some of these assemblies are also well suited for nuclear data validation and to form the basis for criticality safety benchmarks. A number of the Argonne ZPR/ZPPR critical assemblies have been evaluated as ICSBEP and IRPhEP benchmarks. Of the three classes of ZPR assemblies, engineering mockups, engineering benchmarks and physics benchmarks, the last group tends to be most useful for criticality safety. Because physics benchmarks were designed to test fast reactor physics data and methods, they were as simple as possible in geometry and composition. The principal fissile species was {sup 235}U or {sup 239}Pu. Fuel enrichments ranged from 9% to 95%. Often there were only one or two main core diluent materials, such as aluminum, graphite, iron, sodium or stainless steel. The cores were reflected (and insulated from room return effects) by one or two layers of materials such as depleted uranium, lead or stainless steel. Despite their more complex nature, a small number of assemblies from the other two classes would make useful criticality safety benchmarks because they have features related to criticality safety issues, such as reflection by soil-like material. ZPR-3 Assembly 6 consisted of six phases, A through F. In each phase a critical configuration was constructed to simulate a very simple shape such as a slab, cylinder or sphere that could be analyzed with the limited analytical tools available in the 1950s. In each case the configuration consisted of a core region of metal plates surrounded by a thick depleted uranium metal reflector. The average compositions of the core configurations were essentially identical in phases A - F. ZPR-3

  8. ZPR-3 Assembly 12 : A cylindrical assembly of highly enriched uranium, depleted uranium and graphite with an average {sup 235}U enrichment of 21 atom %.

    Energy Technology Data Exchange (ETDEWEB)

    Lell, R. M.; McKnight, R. D.; Perel, R. L.; Wagschal, J. J.; Nuclear Engineering Division; Racah Inst. of Physics

    2010-09-30

    Over a period of 30 years, more than a hundred Zero Power Reactor (ZPR) critical assemblies were constructed at Argonne National Laboratory. The ZPR facilities, ZPR-3, ZPR-6, ZPR-9 and ZPPR, were all fast critical assembly facilities. The ZPR critical assemblies were constructed to support fast reactor development, but data from some of these assemblies are also well suited for nuclear data validation and to form the basis for criticality safety benchmarks. A number of the Argonne ZPR/ZPPR critical assemblies have been evaluated as ICSBEP and IRPhEP benchmarks. Of the three classes of ZPR assemblies, engineering mockups, engineering benchmarks and physics benchmarks, the last group tends to be most useful for criticality safety. Because physics benchmarks were designed to test fast reactor physics data and methods, they were as simple as possible in geometry and composition. The principal fissile species was {sup 235}U or {sup 239}Pu. Fuel enrichments ranged from 9% to 95%. Often there were only one or two main core diluent materials, such as aluminum, graphite, iron, sodium or stainless steel. The cores were reflected (and insulated from room return effects) by one or two layers of materials such as depleted uranium, lead or stainless steel. Despite their more complex nature, a small number of assemblies from the other two classes would make useful criticality safety benchmarks because they have features related to criticality safety issues, such as reflection by soil-like material. ZPR-3 Assembly 12 (ZPR-3/12) was designed as a fast reactor physics benchmark experiment with an average core {sup 235}U enrichment of approximately 21 at.%. Approximately 68.9% of the total fissions in this assembly occur above 100 keV, approximately 31.1% occur below 100 keV, and essentially none below 0.625 eV - thus the classification as a 'fast' assembly. This assembly is Fast Reactor Benchmark No. 9 in the Cross Section Evaluation Working Group (CSEWG) Benchmark

  9. 1-羟基-2-(3,5-二溴-2-吡啶偶氮)-8-氨基-3,6-萘二磺酸的合成及其应用研究%Study on the Synthesis and Apply of 1-Hydroxy-2-(3,5-Dibromo-2-Pyridylazo)-8-Amino-3,6-Naphthalene Disulfonic Acid

    Institute of Scientific and Technical Information of China (English)

    李永忠; 张燮; 陈祥军

    2005-01-01

    采用常见易得无毒的H-酸为主要原料,在H-酸分子骨架上链接分析功能团,制得了1-羟基-2-(3,5-二溴-2-吡啶偶氮)-8-氨基-3,6-萘二磺酸(3,5-diBrPAH),系统研究了3,5-diBrPAH与Cu2+的显色反应及其应用.实验表明,在pH为8.0条件下,Cu2+与该试剂形成1:1的络合物,并且稳定时间达5 h,其最大吸收波长为λ=620 nm,表观摩尔吸光系数为3.27×104 L·mol-1·cm-1, Cu2+浓度在0~25 μg/50 mL范围内符合比耳定律.该法可用于矿石及土壤样中微量铜的测定,简便迅速,结果较令人满意.

  10. 牺牲阳极保护对Q235B钢在模拟海洋潮差区间腐蚀行为的影响%THE EFFECT OF SACRIFICIAL ANODE ON CORROSION PROTECTION OF Q235B STEEL IN SIMULATED TIDAL ZONE

    Institute of Scientific and Technical Information of China (English)

    穆鑫; 魏洁; 董俊华; 柯伟

    2014-01-01

    The environment of the tidal zone is very complex.The interactions of dry-wet alternation and sea erosion lead to serious corrosion of steel structures,which makes it difficult to adopt protective methods.Therefore,it is of great significance to study the corrosion and protection methods of steel in tidal zone.At present,the widely used protection method in tidal zone is coating which is effective in short term.However,it is easy to cause blister failure during the long-term service process,and it will increase the maintenance cost.Sacrificing anode protection is the most common method used in the seawater environment due to its advantages such as low cost,simple operation,no external current,no interference with adjacent metal facilities,good current dispersion ability,easy management and maintenance and high efficiency,etc..However,in the tidal zone,sacrificial anode protective is effective only when the protected metal is in seawater immersion state.After the tide receded,the protected metal exposes in air.At this time,the current loop is destroyed,and the sacrificial anode protection effect is weakened.Therefore,it is commonly known that the sacrificial anode protection method can not protect the whole tidal zone against corrosion.At present,the corrosion process and mechanism of steel structures under sacrificial anode protection in the tidal zone are not clear.In order to study the corrosion mechanism of sacrificial anode protection,a corrosion experimental trough was designed to simulate the tidal zone and immersion zone.The electrode potential of Q235B mild steel under different protecting area of sacrificial anode in it was monitored in situ by the electrochemical workstation.The results show that under the sacrificial anode protection,the long scale specimen of Q235B steel is protected well,the corrosion degree in the tidal zone gradually reduces with the decrease of tide level,and the protected height increases with the increase of sacrificial anode area

  11. Magnetic-field-induced Strain and Energy Consumption of win-boundary Motion in Ni52Mn24.5Ga23.5 Single Crystal%Ni52Mn24.5Ga23.5单晶的磁感生应变及孪晶界移动的能量损耗

    Institute of Scientific and Technical Information of China (English)

    张健; 吴振兴; 李济林; 刘海定; 崔玉亭

    2010-01-01

    测量了不同温度下Ni52Mn24.5Ga23.5 单晶的磁感生应变.温度在280 K(略低于马氏体相变完成温度)时,测量得到的磁感生应变量高达-1.2%;随着温度的降低,磁感生应变量会迅速减小;在250 K的温度下,磁感生应变量仅为-0.37%,结果说明:铁磁形状记忆合金NiMnGa材料的磁感生应变具有明显的温度依赖性.此外,根据热力学理论,计算了在不同温度下,1个循环(升、降磁场)磁感生应变过程中孪晶界移动的能量损耗,结果表明:同种样品、不同温度下的磁感生应变量可定性地反映一个循环过程中孪晶界移动的能量损耗的大小.

  12. Investigation and analysis of reference intervals and medicine decide levels of erythrocyte sedimentation rate in 235 clini-cal laboratories%235家临床实验室红细胞沉降率参考区间和医学决定水平的现况调查∗

    Institute of Scientific and Technical Information of China (English)

    费阳; 王薇; 钟堃; 何法霖; 王治国

    2016-01-01

    Objective To investigate the current situation of reference intervals and medicine decide levels of e-rythrocyte sedimentation rate(ESR)in 235 clinical laboratories all over China.Methods The information related to reference intervals and medicine decide levels was collected by the external quality assessment software system based on website.The participants were classified according to their used instruments.The SPSS 13.0 software was used for conducting the data analysis and obtaining the statistical parameters of reference internals and medicine decide lev-els for each group.Results There were 235 laboratories participating in this investigation,among which 96 laborato-ries reported their medicine decide levels and related data.The primary source of reference intervals was national guide to clinical laboratory procedures (80.85%),followed by textbook (8.5 1%),instructions of instrument and rea-gent manufactures (6.38%),determined by their own laboratory (2.98%)and others.The primary source of medi-cine decide levels was also National Guide to Clinical Laboratory Procedures (75.00%),followed by instructions of instrument and reagent manufactures (1 5.63%).Only 45.1 1% and 46.88% of participant laboratories had the veri-fied reference intervals and medicine decide levels before clinical use,respectively.And 1 68 and 72 participant labora-tories considered different gender when establishing reference intervals and medicine decide levels,respectively.There were no significant differences among the reference intervals of different instrument groups(P >0.05).Conclusion The current situation of reference intervals of ESR in clinical laboratories all over China is unsatisfactory.At present the consistent national standards is urgently needed to guide laboratories to establish suitable reference intervals and medicine decide levels of ESR.%目的:调查全国235家实验室红细胞沉降率(ESR)参考区间和医学决定水平的现状。方法利用基于 Web 方

  13. (238)U/(235)U isotope ratios of crustal material, rivers and products of hydrothermal alteration: new insights on the oceanic U isotope mass balance.

    Science.gov (United States)

    Noordmann, Janine; Weyer, Stefan; Georg, R Bastian; Jöns, Svenja; Sharma, Mukul

    2016-01-01

    In this study, the U isotope composition, n((238)U)/n((235)U), of major components of the upper continental crust, including granitic rocks of different age and post-Archaean shales, as well as that of rivers (the major U source to the oceans) was investigated. Furthermore, U isotope fractionation during the removal of U at mid-ocean ridges, an important sink for U from the oceans, was investigated by the analyses of hydrothermal water samples (including low- and high-temperature fluids), low-temperature altered basalts and calcium carbonate veins. All analysed rock samples from the continental crust fall into a limited range of δ(238)U between -0.45 and -0.21 ‰ (relative to NBL CRM 112-A), with an average of -0.30 ± 0.15 ‰ (2 SD, N = 11). Despite differences in catchment lithologies, all major rivers define a relatively narrow range between -0.31 and -0.13 ‰, with a weighted mean isotope composition of -0.27 ‰, which is indistinguishable from the estimate for the upper continental crust (-0.30 ‰). Only some tributary rivers from the Swiss Alps display a slightly larger range in δ(238)U (-0.29 to +0.01 ‰) and lower U concentrations (0.87-3.08 nmol/kg) compared to the investigated major rivers (5.19-11.69 nmol/kg). These findings indicate that only minor net U isotope fractionation occurs during weathering and transport of material from the continental crust to the oceans. Altered basalts display moderately enriched U concentrations (by a factor of 3-18) compared to those typically observed for normal mid-ocean ridge basalts. These, and carbonate veins within altered basalts, show large U isotope fractionation towards both heavy and light U isotope compositions (ranging from -0.63 to +0.27 ‰). Hydrothermal water samples display low U concentrations (0.3-1 nmol/kg) and only limited variations in their U isotope composition (-0.43 ± 0.25 ‰) around the seawater value. Nevertheless, two of the investigated fluids display

  14. Measurement of neutron-induced fission cross-sections of Th232, U238, U233 and Np237 relative to U235 from 1 MeV to 200 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Shcherbakov, O.A.; Laptev, A.B.; Petrov, G.A. [Petersburg Nuclear Physics Inst., Gatchina, Leningrad district (Russian Federation); Fomichev, A.V.; Donets, A.Y.; Osetrov, O.I.

    1998-11-01

    The measurements of neutron-induced cross-section ratios for Th232, U238, U233 and Np237 relative to U235 have been carried out in the energy range from 1 MeV up to 200 MeV using the neutron time-of-flight spectrometer GNEIS based on 1 GeV proton synchrocyclotron. Below 20 MeV, the results of present measurements are roughly in agreement with evaluated data though there are some discrepances to be resolved. (author)

  15. Preliminary results of calculations for heavy-water nuclear-power-plant reactors employing 235U, 233U, and 232Th as a fuel and meeting requirements of a nonproliferation of nuclear weapons

    Science.gov (United States)

    Ioffe, B. L.; Kochurov, B. P.

    2012-02-01

    A physical design is developed for a gas-cooled heavy-water nuclear reactor intended for a project of a nuclear power plant. As a fuel, the reactor would employ thorium with a small admixture of enriched uranium that contains not more than 20% of 235U. It operates in the open-cycle mode involving 233U production from thorium and its subsequent burnup. The reactor meets the conditions of a nonproliferation of nuclear weapons: the content of fissionable isotopes in uranium at all stages of the process, including the final one, is below the threshold for constructing an atomic bomb, the amount of product plutonium being extremely small.

  16. Uncertainty analyses in the resolved resonance region of {sup 235}U, {sup 238}U, and {sup 239}Pu with the Reich-Moore R-matrix theory for JENDL-3.2

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko [Kyushu University, Interdisciplinary Graduate School of Engineering Sciences, Kasuga, Fukuoka (Japan); Shibata, Keiichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-08-01

    A simple method to estimate covariances for resolved resonance parameters was developed. Although a large number of resolved resonances are observed for major actinides, uncertainties in averaged cross sections are more important than those in resonance parameters in reactor calculations. The method developed here derives a covariance matrix for the resolved resonance parameters which gives an appropriate uncertainty of the averaged cross sections. The method was adopted to evaluate the covariance data for {sup 235}U, {sup 238}U, and {sup 239}Pu resonance parameters in JENDL-3.2, with the Reich-Moore R-matrix formula. (author)

  17. Caracterização mecânica e térmica da borracha natural formulada e vulcanizada dos clones: GT 1, IAN 873, PB 235 e RRIM 600 Mechanical and thermal characterization of compounds of natural rubber of the clones: GT 1, IAN 873, PB 235 and RRIM 600

    Directory of Open Access Journals (Sweden)

    Ana C. Dall'Antonia

    2009-01-01

    Full Text Available Neste trabalho estudou-se o desempenho mecânico e térmico de compostos de borracha natural (Hevea brasiliensis de 4 diferentes clones (GT 1, IAN 873, PB 235 e RRIM 600 cultivados no Estado de São Paulo, assim como de uma mistura destes clones e de uma borracha comercial, GEB-1. Estas borrachas foram formuladas e vulcanizadas com tempos de 5, 7 e 9 minutos. A caracterização foi realizada por calorimetria exploratória diferencial, termogravimetria, ensaios de resistência à tração, análise dinâmico-mecânica, medidas de dureza Shore A, microscopia eletrônica de varredura e espectroscopia na região do infravermelho. Os resultados permitiram concluir que o tempo de vulcanização e o tipo de clone não influenciaram na temperatura de transição vítrea (Tg dos compostos. Os valores de Tg obtidos por DMA foram de cerca de -62 °C, e os resultados ensaios de dureza apresentaram valores próximos de 60 para todos os compostos estudados. Os ensaios de resistência à tração mostraram que o melhor desempenho mecânico foi obtido pelo clone RRIM 600. De acordo com os resultados obtidos neste trabalho, todos os clones atingiram as propriedades reportadas na literatura, podendo ser utilizados, em princípio, nas indústrias de artefatos de borracha separadamente ou na forma de mistura.The objective of this work was to study the mechanical and thermal performance of natural rubber (Hevea brasiliensis compounds of different types of clones (GT 1, IAN 873, PB 235 and RRIM 600, as well as a mixture made from these clones and a commercial rubber GEB-1. These rubbers were formulated and prepared in a two-roll mill and vulcanized at different times (5, 7 and 9 minutes. The evaluation of the mechanical and thermal performance of different natural rubber compounds was carried out by differential scanning calorimetry (DSC, thermogravimetry analysis (TGA, mechanical properties (tensile and hardness tests, dynamic mechanic thermal analysis (DMTA

  18. Estimation of covariances of {sup 16}O, {sup 23}Na, Fe, {sup 235}U, {sup 238}U and {sup 239}Pu neutron nuclear data in JENDL-3.2

    Energy Technology Data Exchange (ETDEWEB)

    Shibata, Keiichi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Nakajima, Yutaka; Kawano, Toshihiko; Oh, Soo-Youl; Matsunobu, Hiroyuki; Murata, Toru

    1997-10-01

    Covariances of nuclear data have been estimated for 6 nuclides contained in JENDL-3.2. The nuclides considered are {sup 16}O, {sup 23}Na, Fe, {sup 235}U, {sup 238}U, and {sup 239}Pu, which are regarded as important for the nuclear design study of fast reactors. The physical quantities for which covariances are deduced are cross sections, resolved and unresolved resonance parameters, and the first order Legendre-polynomial coefficient for the angular distribution of elastically scattered neutrons. As for {sup 235}U, covariances were obtained also for the average number of neutrons emitted in fission. The covariances were estimated by using the same methodology that had been used in the JENDL-3.2 evaluation in order to keep a consistency between mean values and their covariances. The least-squares fitting code GMA was used in estimating covariances for reactions of which JENDL-3.2 cross sections had been evaluated by taking account of measurements. In nuclear model calculations, the covariances were calculated by the KALMAN system. The covariance data obtained were compiled in the ENDF-6 format, and will be put into the JENDL-3.2 Covariance File which is one of JENDL special purpose files. (author). 193 refs.

  19. Fabrication and electromagnetic characteristics of microwave absorbers containing Li{sub 0.35}Zn{sub 0.3}Fe{sub 2.35}O{sub 4} micro-belts and nickel-coated carbon fibers

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Bin, E-mail: zbtyut@126.com [Key Laboratory of Advanced Transducers and Intelligent Control System , Ministry of Education, Taiyuan University of Technology, Taiyuan 030024, Shanxi (China); Wang, Qilei; Zhang, Cunrui [Chinese People’s Armed Police Forces Academy, Langfang 065000, Hebei (China)

    2013-11-15

    Li{sub 0.35}Zn{sub 0.3}Fe{sub 2.35}O{sub 4} micro-belts were prepared by cotton template. The nickel-coated carbon fibers were obtained by electroless plating method. The formation mechanism of the ferrite micro-belt was studied. The electromagnetic properties of the microwave absorbers were investigated in the frequency range of 30–6000 MHz. The double-layer absorbers have better microwave absorption properties than the nickel-coated carbon fibers single-layer absorbers and the microwave absorption properties of the composites are influenced by the thickness of the absorber. - Highlights: • The Li{sub 0.35}Zn{sub 0.3}Fe{sub 2.35}O{sub 4} micro-belts were prepared by cotton template for the first time. • The microwave absorption properties of composites were investigated. • The formation mechanism of the ferrite micro-belt was studied. • The microwave absorption properties of the composites were investigated.

  20. Beta and gamma decay heat measurements between 0.1s-50,000s for neutron fission of {sup 235}U, {sup 238}U and {sup 239}Pu. Progress report, March 1, 1993--January 31, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Schier, W.A.; Couchell, G.P.

    1994-06-01

    Decay heat measurements following the fast fission of {sup 238}U are well underway. The He-jet system and spectrometers were moved to the 1 MW research reactor to gain sufficient fast neutron flux for these measurements. On the Van de Graaff accelerator, the He-jet capillary has been shortened so that beta and gamma measurements following the thermal neutron fission of {sup 235}U could be made down to delay times near 0.1 s. Gamma-ray response functions are now well characterized for gamma energies up to 1.5 MeV for our large Nal spectrometer. Such response functions out to high energies are needed to extract energy distributions of our measured gamma spectra. The response function unfolding program, FERD-PC, has been operated successfully with trial spectra. Comparisons of individual fission products for {sup 235}U(n{sub th}f) with ENDF/B-VI at short delay times suggest several improvements to the data base particularly in production probabilities. The new data acquisition and data analysis systems have arrived and will soon be brought on line extending considerably the capabilities of our research group.

  1. 235U, 238U, 232Th, 40K and 137Cs activity concentrations in marine sediments along the northern coast of Oman Sea using high-resolution gamma-ray spectrometry.

    Science.gov (United States)

    Zare, Mohammad Reza; Mostajaboddavati, Mojtaba; Kamali, Mahdi; Abdi, Mohammad Reza; Mortazavi, Mohammad Seddigh

    2012-09-01

    The natural radioactivity levels in sediment samples of the northern coast of Oman Sea, covering the coastal strip from Hormoz canyon to Goatr seaport, as the first time has been determined. The results of measurements will serve as background reference level for Oman Sea coastlines. Sediments from 36 coastal and near shore locations were collected for analysis. Analysis on the collected samples were carried out to determine (235)U, (238)U, (232)Th, (40)K and (137)Cs using two high purity germanium detectors with 38.5% and 55% relative efficiencies. The concentration of (235)U, (238)U, (232)Th, (40)K and (137)Cs in sediment samples ranged between 1.01 and 2.87 Bq/kg, 11.83 and 22.68 Bq/kg, 10.7 and 25.02 Bq/kg, 222.89 and 535.07 Bq/kg and 0.14 and 2.8 Bq/kg, respectively. The radium equivalent activity was well below the defined limit of 370 Bq/kg. The external hazard indices were found to be less than 1, indicating a low dose.

  2. Microstructure Evolution of Electron Beam Physical Vapour Deposited Ni-23.5Cr-2.66Co-1.44Al Superalloy Sheet During Annealing at 600 °C

    Directory of Open Access Journals (Sweden)

    Li Mingwei

    2013-02-01

    Full Text Available Microstructure evolution of electron beam physical vapour deposited (EB-PVD Ni‑23.5Cr‑2.66Co‑1.44Al superalloy sheet during annealing at 600 °C was investigated. The results showed that the as-deposited alloy was composed of only g phase. After annealing at 600 °C, the locations of diffraction peaks were still the same. The (220 diffraction peak of the deposition side increased with annealing time. The sheet on deposited side had a tendency toward forming (220 texture during post-annealing. No obvious texture was observed at as-deposited and annealed sheet at 600 °C in substrate side. The count and size of "voids" decreased with time. The size of grains increased obviously with annealing time. The ultimate tensile strength of EB-PVD Ni-23.5Cr-2.66Co-1.44Al alloy sheet increased from 641 MPa to 829 MPa after annealing at 600 °C for 30 hours.

  3. Study on Fe-Al Intermetallics Prepared by Plasma Surface Remelting%Q235钢材表面等离子重熔制备Fe-Al金属间化合物

    Institute of Scientific and Technical Information of China (English)

    高伟; 李艳红; 李镇江

    2008-01-01

    在Q235钢试样上刷涂Al粉,并应用等离子表面重熔技术在试样上制备Fe-Al金属化合物覆层.用X射线衍射仪分析了覆层的相组成.用金相显微镜观察组织结构.用显微硬度计测试了Vickers硬度.实验结果得出,覆层中的主相为Fe3Al,次为Fe,含有少量的Al2O3和微量的SiO3:;覆层中的Fe3Al呈针状和短棒状分布;覆层的Vickers硬度达10 000 MPa,较基体的硬度有大幅提高.在Q235钢部件上熔覆Fe3Al金相化合物后提高了耐磨性,耐腐蚀性,并增加部件的结构强度.

  4. Investigation of (235)U, (226)Ra, (232)Th, (40)K, (137)Cs, and heavy metal concentrations in Anzali international wetland using high-resolution gamma-ray spectrometry and atomic absorption spectroscopy.

    Science.gov (United States)

    Zare, Mohammad Reza; Kamali, Mahdi; Fallahi Kapourchali, Maryam; Bagheri, Hashem; Khoram Bagheri, Mahdi; Abedini, Ali; Pakzad, Hamid Reza

    2016-02-01

    Measurements of natural radioactivity levels and heavy metals in sediment and soil samples of the Anzali international wetland were carried out by two HPGe-gamma ray spectrometry and atomic absorption spectroscopy techniques. The concentrations of (235)U, (226)Ra, (232)Th, (40)K, and (137)Cs in sediment samples ranged between 1.05 ± 0.51-5.81 ± 0.61, 18.06 ± 0.63-33.36 ± .0.34, 17.57 ± 0.38-45.84 ± 6.23, 371.88 ± 6.36-652.28 ± 11.60, and 0.43 ± 0.06-63.35 ± 0.94 Bq/kg, while in the soil samples they vary between 2.36-5.97, 22.71-38.37, 29.27-42.89, 472.66-533, and 1.05-9.60 Bq/kg for (235)U, (226)Ra, (232)Th, (40)K, and (137)Cs, respectively. Present results are compared with the available literature data and also with the world average values. The radium equivalent activity was well below the defined limit of 370 Bq/kg. The external hazard indices were found to be less than 1, indicating a low dose. Heavy metal concentrations were found to decrease in order as Fe > Mn > Sr > Zn > Cu > Cr > Ni > Pb > Co > Cd. These measurements will serve as background reference levels for the Anzali wetland.

  5. 三氯酚对小椎实螺急性毒性作用和过氧化物酶活性的影响%Effects of 2,3,5-TCP and 2,3,6-TCP on Acute Toxicity and POD Activity of Galba pervia

    Institute of Scientific and Technical Information of China (English)

    宋志慧; 杨鲁娜

    2012-01-01

    [目的]探讨2,3,5-三氯酚和2,3,6-三氯酚对小椎实螺的毒性指标.[方法]以小椎实螺为供试生物,采用半静态法对小椎实螺进行驯养和试验,测定2,3,5 -TCP和2,3,6-TCP对小椎实螺的半数致死浓度(LC50)、联合毒性作用类型和POD活性的影响.[结果]2,3,5 -TCP和2,3,6-TCP对小椎实螺的96 hLC30分别为0.525和1.925 mg/L,毒性顺序为:2,3,5-TCP >2,3,6-TCP;2,3,5-TCP和2,3,6-TCP的联合作用类型为协同作用;2,3,5-TCP和2,3,6-TCP暴露1d胁迫小椎实螺POD为诱导-抑制效应,暴露3和5d胁迫小椎实螺POD为抑制效应,且随暴露时间的延长,不同酶活性变化显著.[结论]为进一步探讨氧酚对腹足动物的毒性机理以及对氯酚化合物污染的早期诊所与生态风险评级提供了理论依据.%[Objective] To study the toxic effect of 2,3,5-TCP and 2,3,6-TCP on Galbapervia. [ Method] The G. pervia was cultured by semi-static method,the LC50 and joint action of 2,3,5-TCP and 2,3,6-TCP to G. pervia as well as the POD activity were discussed. [Result] The 96 h-LC50, of 2,3,5-TCP and 2,3,6-TCP were 0.525 mg/L and 1.925 mg/L, respectively. The toxicity order of them was 2,3,5-TCP > 2,3,6-TCP,the joint effect of 2,3,5-TCP and 2,3,6-TCP was synergistie; The POD in C.perma exposed to 2,3,5-TCP and 2,3,6-TCP stress was both induced and inhibited,while it was inhibited when the G. pervia was exposed to 2,3,5-TCP and 2,3,6-TCP stress for 3 d and 5 d,the enzyme activities were changed significantly with the extending days of exposure. [ Conclusion ] The study provides theoretical support for further discussing the toxic effect of TCP to G. penna as well as the early diagnosis and risk evaluation of TCP compounds.

  6. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228

    Energy Technology Data Exchange (ETDEWEB)

    Aleissa, Khalid A.; Almasoud, Fahad I.; Islam, Mohammed S. [Atomic Energy Research Institute, King Abdul Aziz City for Science and Technology, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); L' Annunziata, Michael F. [IAEA Expert, Montague Group, P.O. Box 5033, Oceanside, CA 92052-5033 (United States)], E-mail: mlannunziata@cox.net

    2008-12-15

    The activities of {sup 228}Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide {sup 228}Ac. The radium was pre-concentrated on MnO{sub 2} and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter {sup 228}Ra({sup 228}Ac), the daughter nuclide {sup 228}Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by {sup 228}Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9{+-}0.1% was measured for {sup 228}Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317{+-}0.013 cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1 g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of {sup 228}Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for {sup 228}Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure {sup 228}Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  7. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228.

    Science.gov (United States)

    Aleissa, Khalid A; Almasoud, Fahad I; Islam, Mohammed S; L'Annunziata, Michael F

    2008-12-01

    The activities of (228)Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide (228)Ac. The radium was pre-concentrated on MnO(2) and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter (228)Ra((228)Ac), the daughter nuclide (228)Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by (228)Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9+/-0.1% was measured for (228)Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317+/-0.013cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of (228)Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for (228)Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure (228)Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  8. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    Energy Technology Data Exchange (ETDEWEB)

    Rakhimov, A.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz); Warot, G. [CEA-CNRS, Modane (France). Laboratoire Souterrain de Modane (LSM); Karaivanov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Institute for Nuclear Research and Nuclear Energy (INRNE), Sofia (Bulgaria); Kochetov, O.I.; Lebedev, N.A.; Filosofov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Mukhamedshina, N.M.; Sadikov, I.I. [Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz)

    2013-07-01

    A technique of selenium purification from {sup 232}Th, {sup 238}U, {sup 226,228}Ra, {sup 227}Ac and {sup 40}K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  9. The release of dissolved actinium to the ocean: A global comparison of different end-members

    Science.gov (United States)

    Geibert, W.; Charette, M.; Kim, G.; Moore, W.S.; Street, J.; Young, M.; Paytan, A.

    2008-01-01

    The measurement of short-lived 223Ra often involves a second measurement for supported activities, which represents 227Ac in the sample. Here we exploit this fact, presenting a set of 284 values on the oceanic distribution of 227Ac, which was collected when analyzing water samples for short-lived radium isotopes by the radium delayed coincidence counting system. The present work compiles 227Ac data from coastal regions all over the northern hemisphere, including values from ground water, from estuaries and lagoons, and from marine end-members. Deep-sea samples from a continental slope off Puerto Rico and from an active vent site near Hawaii complete the overview of 227Ac near its potential sources. The average 227Ac activities of nearshore marine end-members range from 0.4??dpm m- 3 at the Gulf of Mexico to 3.0??dpm m- 3 in the coastal waters of the Korean Strait. In analogy to 228Ra, we find the extension of adjacent shelf regions to play a substantial role for 227Ac activities, although less pronounced than for radium, due to its weaker shelf source. Based on previously published values, we calculate an open ocean 227Ac inventory of 1.35 * 1018??dpm 227Acex in the ocean, which corresponds to 37??moles, or 8.4??kg. This implies a flux of 127??dpm m-2 y- 1 from the deep-sea floor. For the shelf regions, we obtain a global inventory of 227Ac of 4.5 * 1015??dpm, which cannot be converted directly into a flux value, as the regional loss term of 227Ac to the open ocean would have to be included. Ac has so far been considered to behave similarly to Ra in the marine environment, with the exception of a strong Ac source in the deep-sea due to 231Paex. Here, we present evidence of geochemical differences between Ac, which is retained in a warm vent system, and Ra, which is readily released [Moore, W.S., Ussler, W. and Paull, C.K., 2008-this issue. Short-lived radium isotopes in the Hawaiian margin: Evidence for large fluid fluxes through the Puna Ridge. Marine Chemistry]. Another potential mechanism of producing deviations in 227Ac/228Ra and daughter isotope ratios from the expected production value of lithogenic material is observed at reducing environments, where enrichment in uranium may occur. The presented data here may serve as a reference for including 227Ac in circulation models, and the overview provides values for some end-members that contribute to the global Ac distribution. ?? 2007 Elsevier B.V. All rights reserved.

  10. Osmanlı Toplumunda Kadınların Mahkeme Önündeki Hukuk Mücadelesi: 235 No’lu Seydişehir Şer’iyye Sicil Defterine Göre Women’s Legal Struggle at Court in Ottomon Society: According to 235 Seydişehir Legal Register

    Directory of Open Access Journals (Sweden)

    Mehmet Emin ŞEN

    2012-12-01

    Full Text Available The past is a matter of curiasity for human being. There are people who are interested in how others lived and what they did in the past apart from wars and politicks. İt is impossible to find this interesting topicks in the history book which gives information about political events but, there are a lot of inforation about the lifestyle ofthat period people in the documents that were written during theOttomon Empire. The Ottomon sent a judge even if the smallest districtit ruled for registering each event that occured. This registers, whichhave been protected under the name of legal registers, are our of themost important cultural heritages. Thanks to this registers, we getoriginal information about the daily lifestyleof Ottomon society. İnKonya, Seydişehir, 12 records were kept by judges, which was a smalldistrict of Ottomon in 1890 for this Article, the 235 Seydişehir legalregister has been analysed the most important part of this register isthat there was 67 court case and must of them were about women.With the help of this precious register which includes lots of roughinformation about women in Ottomon and her effects, it has beenestablished that the women weren’t exposed to inequality in point ofsocial; they were as active as the men to insist on themselves rights,using within limits determined by the law codes. In this work curiositiesabout Ottoman women and their way of searching for justice will besatisfied through Seydişehir example. Geçmiş, insanlar tarafından her zaman ilgi görmüştür ve ilgi görmeye de devam edecektir. Savaşlar ve siyaset dışında, özellikle toplumda yaşayan bireylerin geçmişte nasıl yaşadığı ve neler yaptığı ise ayrı bir merak konusu olmuştur. Bu ilginç konuları, siyasi olayların ele alındığı tarih kitaplarında bulmak mümkün değildir. Ancak Osmanlı Devleti döneminde tutulan defterler, kayıtlar ve belgelerde o dönem insanlarının günlük yaşamı ile ilgili az

  11. 在肿瘤细胞模型中联合应用磷脂酰肌醇3激酶/蛋白酶B通路抑制剂BEZ235和细胞外调解蛋白激酶/丝裂原活化蛋白激酶通路抑制剂U0126的效果%Efficacy of Combination Treatment of the Inhibitor of Phosphatidyl Inositol-3-Kinase/Protein Kinase B Pathway BEZ235 and the Inhibitor of Extracellular Regulated Protein Kinase/Mitogen-activated Protein Kinase Pathway U0126 in A Tumor Cell Model

    Institute of Scientific and Technical Information of China (English)

    陈欣欣; 张舒; 石玉镯

    2013-01-01

    目的 探讨通过联合应用磷脂酰肌醇3激酶(PI3K)/蛋白酶B(AKT)通路抑制剂BEZ235和细胞外调解蛋白激酶(ERK)通路抑制剂U0126抑制膜受体酪氨酸激酶/PI3K/AKT/雷帕霉素靶蛋白(mTOR)通路与ERK/丝裂原活化蛋白激酶通路对细胞增殖的影响.方法 以磷酸酶和张力蛋白同源物缺失(PTEN-/-)的小鼠胚胎成纤维细胞(MEF)系作为研究对象,联合应用PI3K、mTOR双重抑制剂BEZ235及ERK激酶抑制剂U0126,通过MTT和Western blot方法检测药物对细胞增殖的影响.结果 BEZ235及U0126对PTEN-/-MEF细胞均有抑制作用,二者半数抑制浓度分别为6.257 nmol/L及22.85 μmol/L.但联合应用BEZ235与U0126,二者表现为拮抗的作用方式.结论 在PTEN缺失的细胞系中或PTEN突变的肿瘤的联合靶向治疗中,不推荐应用BEZ235与U0126联合使用.

  12. Effects of rotation of fissioning nuclei in the angular distributions of prompt neutrons and gamma rays originating from the polarized-neutron-induced fission of 233U and 235U nuclei

    Science.gov (United States)

    Danilyan, G. V.; Klenke, J.; Kopach, Yu. N.; Krakhotin, V. A.; Novitsky, V. V.; Pavlov, V. S.; Shatalov, P. B.

    2014-06-01

    The results of an experiment devoted to searches for effects of rotation of fissioning nuclei in the angular distributions of prompt neutrons and gamma rays originating from the polarized-neutron-induced fission of 233U nuclei are presented. The effects discovered in these angular distributions are opposite in sign to their counterparts in the polarized-neutron-induced fission of 235U nuclei. This is at odds with data on the relative signs of respective effects in the angular distribution of alpha particles from the ternary fission of the same nuclei and may be indicative of problems in the model currently used to describe the effect in question. The report on which this article is based was presented at the seminar held at the Institute of Theoretical and Experimental Physics and dedicated to the 90th anniversary of the birth of Yu.G. Abov, corresponding member of Russian Academy of Sciences, Editor in Chief of the journal Physics of Atomic Nuclei.

  13. Mathematical Analysis of a Series of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl-6-pyridylpyrimidines: A Simple Way to Relate Quantum Similarity to Local Chemical Reactivity Using the Gaussian Orbitals Localized Theory

    Directory of Open Access Journals (Sweden)

    Alejandro Morales-Bayuelo

    2014-01-01

    Full Text Available Molecular Quantum Similarity (MQS descriptors and Density Functional Theory (DFT based reactivity descriptors were studied for a series of 4-Acetylamino-2-(3,5-dimethylpyrazol-1-yl-6-pyridylpyrimidines compounds used for Parkinson’s disease (PD treatment. The quantification of the steric and electronic effects was shown through scales of quantitative convergence; such scales allow us to establish a methodology to quantify the similarity from the local chemical reactivity (Fukui Functions point of view. This procedure provides new considerations in the local reactivity of the A2A Adenosine receptor antagonists in a disease of difficult control as PD. In addition, we present new considerations to the localized bonding theory and show a new methodology for quantum similarity on the Fukui Functions. Considering that the Fukui functions under a condensation scheme may have ambiguities in the (DFT context.

  14. Stereochemistry of Pd(II)-Catalyzed THF Ring Formation of ε-Hydroxy Allylic Alcohols and Synthesis of 2,3,5-Trisubstituted and 2,3,4,5-Tetrasubstituted Tetrahydrofurans.

    Science.gov (United States)

    Murata, Yuki; Uenishi, Jun'ichi

    2016-09-02

    Pd(II)-catalyzed ring formation of 2,3,5-trisubstituted and 2,3,4,5-tetrasubstituted tetrahydrofurans is described. Oxypalladation of a chiral ε-hydroxy allylic alcohol provides a 5-alkenyltetrahydrofuran ring in excellent yields via a 5-exo-trigonal process. Nine substrates including six secondary allylic alcohols and three primary allylic alcohols with or without an additional secondary hydroxy substituent at the γ-position have been examined. Their structures are restricted by a 2,2,4,4-tetraisopropyl-1,3,5,2,4-trioxadisilocane ring. The stereochemistry of the resulting tetrahydrofuran products was determined by chemical transformation. The reaction mechanism is discussed on the basis of the stereochemical results. The steps in the chiral allylic alcohol directed or the nucleophilic alcohol directed facial selection for the formation of the alkene-Pd(II)-π-complex, the cis-oxypalladation, and a syn-elimination mechanism account for the observed stereochemistry of the reaction.

  15. New measurements of (n,γ) and (n,fission) cross sections and capture-to-fission ratios for ^233,235U and ^239Pu using the DANCE 4π BaF2 array

    Science.gov (United States)

    Bredeweg, T. A.; Jandel, M.; Fowler, M. M.; Bond, E. M.; Haight, R. C.; Keksis, A. L.; O'Donnell, J. M.; Reifarth, R.; Rundberg, R. S.; Ullmann, J. L.; Vieira, D. J.; Wilhelmy, J. B.; Wouters, J. M.; Becker, J. A.; Parker, W. E.; Wu, C. Y.; Baker, J. D.; McGrath, C. A.

    2009-10-01

    Accurate neutron nuclear data are important to many issues in stockpile stewardship, nuclear reactor design and re-certification, nuclear non-proliferation and nuclear forensics. Of particular interest are the production and destruction reactions for all of the major and most of the minor actinides. The competition between capture and fission in many of the actinides presents both an obstacle and an opportunity for large γ detector arrays such as DANCE. Additional instrumentation is required to deconvolve the two contributions to the total observed γ-ray spectrum. However, conducting a simultaneous measurement can simplify background treatment and other sources of systematic uncertainty. An outline of the current experimental program will be presented along with results from neutron capture measurements on ^233,235U and ^239Pu.

  16. A study of reversible gamma-induced structural transformations in vitreous Ge23.5Sb11.8S64.7 by high-resolution X-ray photoelectron spectroscopy.

    Science.gov (United States)

    Kovalskiy, Andriy; Jain, Himanshu; Miller, Alfred C; Golovchak, Roman Ya; Shpotyuk, Oleh I

    2006-11-16

    The structural origin of reversible gamma-induced effects in vitreous Ge(23.5)Sb(11.8)S(64.7) has been investigated by high-resolution X-ray photoelectron spectroscopy (XPS). The changes in valence band spectrum from gamma-irradiation suggest a decrease of sulfur lone pair electron concentration accompanied by changes in bonding states of S and Ge. The appearance of additional doublets in the core-level XPS spectra of Ge, Sb, and S atoms for gamma-irradiated sample is described by the formation of over- and under-coordinated charged defect pairs (Ge(3)(-)-S(3)(+)) as a result of radiation treatment. The results verify the switching of Ge-S covalent bonds into S-S bonds as the main microstructural mechanism for gamma-induced optical effects in this glass.

  17. The Arizona Radio Observatory CO Mapping Survey of Galactic Molecular Clouds. V. The Sh2-235 Cloud in CO J=2-1, 13CO J=2-1, and CO J=3-2

    Science.gov (United States)

    Bieging, John H.; Patel, Saahil; Peters, William L.; Toth, L. Viktor; Marton, Gábor; Zahorecz, Sarolta

    2016-09-01

    We present the results of a program to map the Sh2-235 molecular cloud complex in the CO and 13CO J = 2 - 1 transitions using the Heinrich Hertz Submillimeter Telescope. The map resolution is 38″ (FWHM), with an rms noise of 0.12 K brightness temperature, for a velocity resolution of 0.34 km s-1. With the same telescope, we also mapped the CO J = 3 - 2 line at a frequency of 345 GHz, using a 64 beam focal plane array of heterodyne mixers, achieving a typical rms noise of 0.5 K brightness temperature with a velocity resolution of 0.23 km s-1. The three spectral line data cubes are available for download. Much of the cloud appears to be slightly sub-thermally excited in the J = 3 level, except for in the vicinity of the warmest and highest column density areas, which are currently forming stars. Using the CO and 13CO J = 2 - 1 lines, we employ an LTE model to derive the gas column density over the entire mapped region. Examining a 125 pc2 region centered on the most active star formation in the vicinity of Sh2-235, we find that the young stellar object surface density scales as approximately the 1.6-power of the gas column density. The area distribution function of the gas is a steeply declining exponential function of gas column density. Comparison of the morphology of ionized and molecular gas suggests that the cloud is being substantially disrupted by expansion of the H ii regions, which may be triggering current star formation.

  18. Formation of super-concentrated hydrochloric acid in the third phase in tertiary amine N235-PtCl62--HCl system and its influences on the Pt microemulsion extraction

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper,we have investigated the formation of the third-phase in tertiary amine(N235)-PtCl62--HCl system and the microscopic phase structural evolution of platinum-loaded organic phases before and after the occurrence of the third-phase.The third-phase is characterized by various spectroscopic techniques,and the small angle X-ray scattering(SAXS) experiments demonstrate the appearance of nano-aggregates,i.e.,water-in-oil reversed micelles,in the third phase.The experimental results indicate that(1) formation of the third phase is related to the aggregation behaviors of nano-reversed micelles in which a super-concentrated hydrochloric acid formed with the H+ to H2O molar ratio being much higher than that of the conventional 37 wt% saturated hydrochloric acid.(2) The occurrence of the super-concentrated HCl results in a great amount of H+ and Cl-ions enriched and confined within the nano-water pools of W/O reversed micelles in third phase.Therefore,the coordination behaviors of platinum complex ions in that super-concentrated hydrochloric acid are very different from their corresponding behaviors in bulk aqueous solutions.It is possible that H+ ions participate in the formation of such complexes as HmPtCl6z+ in the super-concentrated hydrochloric acid.(3) The relative contents of various HmPtCl6z+ complexes are different corresponding to the H+ ion concentrations in confined nanowater pools.The association ability of the acidified tertiary amine N235 molecules(R3NH+) with various HmPtCl6z+ complexes plays an important role in affecting the platinum extraction behaviors.

  19. 2,3,5-Triphenyl-2H-tetrazolium Chloride and 2,4,6-Tri(2-pyridyl)-s-triazine on the Corrosion of Mild Steel in HCl%氯化2,3,5.三苯基-2氢-四唑及2,4,6-三(2-吡啶基)-s-三嗪在HC1中对碳钢的缓蚀作用

    Institute of Scientific and Technical Information of China (English)

    庞雪辉; 侯保荣; 李伟华; 刘法谦; 于志刚

    2007-01-01

    Electrochemical measurement, quantum chemical method, and scanning electron microscopy (SEM)were performed to investigate the inhibitive effect of 2,3,5-triphenyl-2H-tetrazolium chloride (TTC) and spectroscopy measurement showed that the polarization resistance increased and that double layer capacitance decreased with the increase in the inhibitive concentration, and the results of potentiodynamic polarization showed that the inhibitors suppressed both cathodic and anodic processes of steel corrosion without change in the mechanism. Higher the orbital density distribution strength of the lowest unoccupied molecular orbital, higher is the molecule dipole, and lower energy gap between the energy of the highest occupied molecular orbital and the energy of the lowest unoccupied molecular orbital resulted in higher inhibitory efficiency. The results of SEM analysis showed that the metal was protected from aggressive corrosion by the addition of TTC and TPT.

  20. Decay Heat Analyses after Thermal-Neutron Fission of {sup 235}U and {sup 239}Pu by SCALE-6.1.3 with Recently Available Fission Product Yield Data

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Do Heon; Gil, Choong-Sup; Lee, Young-Ouk [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The heat reaches about 1.5% after one hour and falls to 0.4% after a day. After a week it will be about 0.2%. The reactor, however, still requires further cooling for several years to keep the fuel rods safe. In general, the decay heat in the reactors can be calculated using a summation calculation method, which is simply the sum of the activities of the fission products produced during the fission process and after the reactor shutdown weighted by the mean decay energies. Consequently, the method is strongly dependent on the available nuclear structure data. Nowadays, the method has been implemented in various burnup and depletion programs such as ORIGEN and CINDER. In this study, the decay heat measurements after thermal-neutron fission of {sup 235}U and {sup 239}Pu have been evaluated by the ORIGEN-S with the decay data and fission product yield libraries included in the SCALE-6.1.3 software package. The new libraries were applied to the decay heat calculations, and the results were compared with those by the ORIGEN reference calculation. The decay heat measurements for very short cooling times after thermal-neutron fission of {sup 235}U and {sup 239}Pu have been evaluated by the ORIGEN-S summation calculation. The reference calculation results by the latest ORIGEN data libraries of the SCALE-6.1.3 have been validated with the measurements by ORNL and Studsvik. In addition, the generation of the new ORIGEN yield libraries has been completed based on the ENDF/B-VII.1, JEFF-3.1.1, JENDL/FPY-2011, and JENDL-4.0. The new libraries have been successfully applied to the decay heat calculations and comparative analyses have been devoted to verifying the importance of the fission product yield data when estimating the decay heat values for each isotope in a very short time. The decay data library occupies an important position in the ORIGEN summation calculation along with the fission product yield library.

  1. Behaviour of uranium series radionuclides in surface water (Crouzille, Limousin). Geochemical implications; Comportement des radionucleides des familles de l'uranium dans les eaux superficielles du site de la Crouzille (Limousin): implications geochimiques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-06-15

    Understanding natural radionuclides behaviour in surface water is a required step to achieve uranium mine rehabilitation and preserve water quality. The first objective of this thesis is to determine which are the radionuclides sources in a drinking water reservoir. The second objective is to improve the knowledge about the behaviour of uranium series radionuclides, especially actinium. The investigated site is a brook (Sagnes, Limousin, France) which floods a peat bog contaminated by a former uranium mine and which empties into the Crouzille lake. It allows studying radionuclides transport in surface water and radionuclides retention through organic substance or water reservoir. Radionuclides distribution in particulate, colloidal and dissolved phases is determined thanks to ultra-filtrations. Gamma spectrometry allows measuring almost all natural radionuclides with only two counting stages. However, low activities of {sup 235}U series radionuclides impose the use of very low background well-type Ge detectors, such as those of the Underground Laboratory of Modane (France). Firstly, this study shows that no or few radionuclides are released by the Sagnes peat bog, although its radioactivity is important. Secondly, it provides details on the behaviour of uranium series radionuclides in surface water. More specifically, it provides the first indications of actinium solubility in surface water. Actinium's behaviour is very close to uranium's even if it is a little less soluble. (author)

  2. In Vivo Emergence of Resistance to Novel Cephalosporin-β-Lactamase Inhibitor Combinations through the Duplication of Amino Acid D149 from OXA-2 β-Lactamase (OXA-539) in Sequence Type 235 Pseudomonas aeruginosa.

    Science.gov (United States)

    Fraile-Ribot, Pablo A; Mulet, Xavier; Cabot, Gabriel; Del Barrio-Tofiño, Ester; Juan, Carlos; Pérez, José L; Oliver, Antonio

    2017-09-01

    Resistance development to novel cephalosporin-β-lactamase inhibitor combinations during ceftazidime treatment of a surgical infection by Pseudomonas aeruginosa was investigated. Both initial (97C2) and final (98G1) isolates belonged to the high-risk clone sequence type (ST) 235 and were resistant to carbapenems (oprD), fluoroquinolones (GyrA-T83I, ParC-S87L), and aminoglycosides (aacA7/aacA8/aadA6). 98G1 also showed resistance to ceftazidime, ceftazidime-avibactam, and ceftolozane-tazobactam. Sequencing identified blaOXA-2 in 97C2, but 98G1 contained a 3-bp insertion leading to the duplication of the key residue D149 (designated OXA-539). Evaluation of PAO1 transformants producing cloned OXA-2 or OXA-539 confirmed that D149 duplication was the cause of resistance. Active surveillance of the emergence of resistance to these new valuable agents is warranted. Copyright © 2017 American Society for Microbiology.

  3. 对应4K超精细画面的高端编织式透声幕 InovaTech Cine Deluxe 180英寸2.35:1弧形框架幕

    Institute of Scientific and Technical Information of China (English)

    Vinssen.Lee

    2012-01-01

    大家平常到电影院中看电影的时候,有没有注意电影中的前方声音是从哪里传出来的?其实,秘密就在于电影院所使用的投影幕。目前大部分电影院中使用的投影幕都是具备声音穿透功能的透声幕,为了让观众看到最大的画面,避免音箱对影像产生遮掩,电影院会将前方声道的音箱隐藏在幕布后方。使用透声幕最大的优势在于能够将声与画很好地结合在一起,展现更加震撼的影音效果。来自美国的InovaTech专注于家庭影院的投影幕与变形镜头的研发,特别在透声幕方面取得了不错的进展。其中,Cine Deluxe 180英寸2.35:1弧形框架幕就是一款特别针对豪宅别墅而推出的高端透声幕。

  4. Estimation of multi-group cross section covariances for {sup 235,238}U, {sup 239}Pu, {sup 241}Am, {sup 56}Fe, {sup 23}Na and {sup 27}Al

    Energy Technology Data Exchange (ETDEWEB)

    De Saint Jean, C.; Archier, P.; Noguere, G.; Litaize, O.; Vaglio-Gaudard, C.; Bernard, D.; Leray, O. [CEA, DEN, DER, Cadarache, F-13108 Saint-Paul-lez-Durance (France)

    2012-07-01

    This paper presents the methodology used to estimate multi-group covariances for some major isotopes used in reactor physics. The starting point of this evaluation is the modelling of the neutron induced reactions based on nuclear reaction models with parameters. These latest are the vectors of uncertainties as they are absorbing uncertainties and correlation arising from the confrontation of nuclear reaction model to microscopic experiment. These uncertainties are then propagated towards multi-group cross sections. As major breakthroughs were then asked by nuclear reactor physicists to assess proper uncertainties to be used in applications, a solution is proposed by the use of integral experiment information at two different stages in the covariance estimation. In this paper, we will explain briefly the treatment of all type of uncertainties, including experimental ones (statistical and systematic) as well as those coming from validation of nuclear data on dedicated integral experiment (nuclear data oriented). We will illustrate the use of this methodology with various isotopes such as {sup 235,238}U, {sup 239}Pu, {sup 241}Am, {sup 56}Fe, {sup 23}Na and {sup 27}Al. (authors)

  5. Mo{sub 2}NiB{sub 2}-type (Gd, Tb, Dy){sub 2}Ni{sub 2.35}Si{sub 0.65} and La{sub 2}Ni{sub 3}-type (Dy, Ho){sub 2}Ni{sub 2.5}Si{sub 0.5} compounds: Crystal structure and magnetic properties

    Energy Technology Data Exchange (ETDEWEB)

    Morozkin, A.V., E-mail: morozkin@tech.chem.msu.ru [Department of Chemistry, Moscow State University, Leninskie Gory, House 1, Building 3, Moscow 119992, GSP-2 (Russian Federation); Isnard, O. [CNRS, Insitut. Néel, 25 rue des Martyrs BP166, F-38042 Grenoble (France); Université Grenoble Alpes, Inst. Néel, F-38042 Grenoble (France); Nirmala, R. [Indian Institute of Technology Madras, Chennai 600 036 (India); Malik, S.K. [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Natal 59082-970 (Brazil)

    2015-05-15

    The crystal structure of new Mo{sub 2}NiB{sub 2}-type (Gd, Tb, Dy){sub 2}Ni{sub 2.35}Si{sub 0.65} (Immm, No. 71, oI10) and La{sub 2}Ni{sub 3}-type (Dy, Ho){sub 2}Ni{sub 2.5}Si{sub 0.5} (Cmce No. 64, oC20) compounds has been established using powder X-ray diffraction studies. Magnetization measurements show that the Mo{sub 2}NiB{sub 2}-type Gd{sub 2}Ni{sub 2.35}Si{sub 0.65} undergoes a ferromagnetic transition at ~66 K, whereas isostructural Tb{sub 2}Ni{sub 2.35}Si{sub 0.65} shows an antiferromagnetic transition at ~52 K and a field-induced metamagnetic transition at low temperatures. Neutron diffraction study shows that, in zero applied field, Tb{sub 2}Ni{sub 2.35}Si{sub 0.65} exhibits c-axis antiferromagnetic order with propagation vector K=[1/2, 0, 1/2] below its magnetic ordering temperature and Tb magnetic moment reaches a value of 8.32(5) μ{sub B} at 2 K. The La{sub 2}Ni{sub 3}-type Dy{sub 2}Ni{sub 2.5}Si{sub 0.5} exhibits ferromagnetic like transition at ~42 K with coexisting antiferromagnetic interactions and field induced metamagnetic transition below ~17 K. The magnetocaloric effect of Gd{sub 2}Ni{sub 2.35}Si{sub 0.65}, Tb{sub 2}Ni{sub 2.35}Si{sub 0.65} and Dy{sub 2}Ni{sub 2.5}Si{sub 0.5} is calculated in terms of isothermal magnetic entropy change and it reaches a maximum value of −14.3 J/kg K, −5.3 J/kg K and −10.3 J/kg K for a field change of 50 kOe near 66 K, 52 K and 42 K, respectively. Low temperature magnetic ordering with enhanced anisotropic effects in Tb{sub 2}Ni{sub 2.35}Si{sub 0.65} and Dy{sub 2}Ni{sub 2.35}Si{sub 0.65} is accompanied by a positive magnetocaloric effect with isothermal magnetic entropy changes of +12.8 J/kg K and ~+9.9 J/kg K, respectively at 7 K for a field change of 50 kOe. - Graphical abstract: The (Gd, Tb, Dy){sub 2}Ni{sub 2.35}Si{sub 0.65} supplement the series of Mo{sub 2}NiB{sub 2}-type rare earth compounds, whereas the (Dy, Ho){sub 2}Ni{sub 2.5}Si{sub 0.5} supplement the series of La{sub 2}Ni{sub 3}-type rare

  6. 21 CFR 172.235 - Morpholine.

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    2010-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN..., subject to the following restrictions. (a) It is used as the salt(s) of one or more of the fatty acids... effect....

  7. 38 CFR 23.235 - Statutory amendments.

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  8. 45 CFR 618.235 - Statutory amendments.

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  9. 22 CFR 229.235 - Statutory amendments.

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    ... legal abortion. Accordingly, subject to paragraph (d)(1) of this section, no person shall be excluded... received, or is seeking, a legal abortion, or any benefit or service related to a legal abortion. ... abortion. Medical procedures, benefits, services, and the use of facilities, necessary to save the life of...

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  11. 10 CFR 5.235 - Statutory amendments.

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  12. 40 CFR 5.235 - Statutory amendments.

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  15. 49 CFR 25.235 - Statutory amendments.

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  16. 18 CFR 1317.235 - Statutory amendments.

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  17. 15 CFR 8a.235 - Statutory amendments.

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  18. 10 CFR 1042.235 - Statutory amendments.

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    ... legal abortion. Accordingly, subject to paragraph (d)(1) of this section, no person shall be excluded... received, or is seeking, a legal abortion, or any benefit or service related to a legal abortion. ... abortion. Medical procedures, benefits, services, and the use of facilities, necessary to save the life of...

  19. 24 CFR 3.235 - Statutory amendments.

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  20. 22 CFR 146.235 - Statutory amendments.

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  1. 43 CFR 41.235 - Statutory amendments.

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  2. 45 CFR 235.110 - Fraud.

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    ... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES ADMINISTRATION OF FINANCIAL ASSISTANCE... officials situations in which there is valid reason to suspect that fraud has been practiced. The definition... legal rights of persons involved and are consistent with the principles recognized as affording due...

  3. 28 CFR 54.235 - Statutory amendments.

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    ... appearance, poise, and talent. The pageant, however, must comply with other nondiscrimination provisions of... from participation in, be denied the benefits of, or be subjected to discrimination under any...

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  5. 13 CFR 113.235 - Statutory amendments.

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    ...) The date of acquisition of each dog or cat; (5) The official USDA tag number or tattoo assigned to... sections of the Freedom of Information Act. Whenever the Administrator notifies a research facility...

  11. 24 CFR 235.1208 - Eligible mortgagors.

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    ... cooperative member must meet the requirements for the disclosure and verification of Social Security Numbers... Requirements: Contract Rights and Obligations; Assistance Payments Contracts; Servicing Responsibilities... submitting of consent forms by mortgagors and cooperative members for the obtaining of wage and claim...

  12. Reference: 235 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available ers in Arabidopsis thaliana (L.) Heynh that encode multicopper oxidase-like proteins that are related to fer...roxidases, ascorbate oxidases and laccases. Only one member of the family has been pre...ke SKU5 appears to lack a functional copper-binding site and is most closely related to Bp10 from Brassica n...apus and Ntp303 from Nicotiana tobacum. The SKS6 promoter contains many putative re...gulatory sites and differential expression of an SKS6::GUS reporter gene revealed selective induction in s

  13. 7 CFR 916.235 - Delinquent assessments.

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    ... late payment charge on any assessment that has not been received in the Nectarine Administrative... shown on the handler's assessment statement. The late payment charge shall be 10 percent of the unpaid balance. (b) In addition to that specified in paragraph (a) of this section, the Nectarine Administrative...

  14. 50 CFR 600.235 - Financial disclosure.

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    ... entities is covered by 18 U.S.C. 208, the Federal conflict-of-interest statute. (b) Reporting. (1) The... disclosure. Link to an amendment published at 75 FR 59152, Sept. 27, 2010. (a) Definitions. For purposes of... ownership interests in, or employment with, any company, business, fishing vessel, or other entity...

  15. EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activity

    Science.gov (United States)

    Allhorn, Maria; Olsén, Arne; Collin, Mattias

    2008-01-01

    Background The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies and thus enhance bacterial survival in human blood. In this study, we further investigated the relationship between EndoS and SpeB by examining their in vitro temporal production and stability and activity of EndoS. Furthermore, theoretical structure modeling of EndoS combined with site-directed mutagenesis and chemical blocking of amino acids was used to identify amino acids required for the IgG glycan-hydrolyzing activity of EndoS. Results We could show that during growth in vitro S. pyogenes secretes the IgG glycan-hydrolyzing endoglycosidase EndoS prior to the cysteine proteinase SpeB. Upon maturation SpeB hydrolyzes EndoS that then loses its IgG glycan-hydrolyzing activity. Sequence analysis and structural homology modeling of EndoS provided a basis for further analysis of the prerequisites for IgG glycan-hydrolysis. Site-directed mutagenesis and chemical modification of amino acids revealed that glutamic acid 235 is an essential catalytic residue, and that tryptophan residues, but not the abundant lysine or the single cysteine residues, are important for EndoS activity. Conclusion We present novel information about the amino acid requirements for IgG glycan-hydrolyzing activity of the immunomodulating enzyme EndoS. Furthermore, we show that the cysteine proteinase SpeB processes/degrades EndoS and thus emphasize the importance of the SpeB as a degrading/processing enzyme of proteins from the bacterium itself. PMID:18182097

  16. Observation of a re-entrant phase transition in the molecular complex tris(μ2-3,5-diisopropyl-1,2,4-triazolato-κ2N1:N2trigold(I under high pressure

    Directory of Open Access Journals (Sweden)

    Christopher H. Woodall

    2016-09-01

    Full Text Available We report a molecular crystal that exhibits four successive phase transitions under hydrostatic pressure, driven by aurophilic interactions, with the ground-state structure re-emerging at high pressure. The effect of pressure on two polytypes of tris(μ2-3,5-diisopropyl-1,2,4-triazolato-κ2N1:N2trigold(I (denoted Form-I and Form-II has been analysed using luminescence spectroscopy, single-crystal X-ray diffraction and first-principles computation. A unique phase behaviour was observed in Form-I, with a complex sequence of phase transitions between 1 and 3.5 GPa. The ambient C2/c mother cell transforms to a P21/n phase above 1 GPa, followed by a P21/a phase above 2 GPa and a large-volume C2/c supercell at 2.70 GPa, with the previously observed P21/n phase then reappearing at higher pressure. The observation of crystallographically identical low- and high-pressure P21/n phases makes this a rare example of a re-entrant phase transformation. The phase behaviour has been characterized using detailed crystallographic theory and modelling, and rationalized in terms of molecular structural distortions. The dramatic changes in conformation are correlated with shifts of the luminescence maxima, from a band maximum at 14040 cm−1 at 2.40 GPa, decreasing steeply to 13550 cm−1 at 3 GPa. A similar study of Form-II displays more conventional crystallographic behaviour, indicating that the complex behaviour observed in Form-I is likely to be a direct consequence of the differences in crystal packing between the two polytypes.

  17. NEUTRON TOTAL CROSS SECTIONS OF 235U FROM TRANSMISSION MEASUREMENTS IN THE ENERGY RANGE 2 keV to 300 keV AND STATISTICAL MODEL ANALYSIS OF THE DATA

    Energy Technology Data Exchange (ETDEWEB)

    Derrien, H.

    2000-05-22

    The average {sup 235}U neutron total cross sections were obtained in the energy range 2 keV to 330 keV from high-resolution transmission measurements of a 0.033 atom/b sample. The experimental data were corrected for the contribution of isotope impurities and for resonance self-shielding effects in the sample. The results are in very good agreement with the experimental data of Poenitz et al. in the energy range 40 keV to 330 keV and are the only available accurate experimental data in the energy range 2 keV to 40 keV. ENDF/B-VI evaluated data are 1.7% larger. The SAMMY/FITACS code was used for a statistical model analysis of the total cross section, selected fission cross sections and {alpha} data in the energy range 2 keV to 200 keV. SAMMY/FITACS is an extended version of SAMMY which allows consistent analysis of the experimental data in the resolved and unresolved resonance region. The Reich-Moore resonance parameters were obtained from a SAMMY Bayesian fits of high resolution experimental neutron transmission and partial cross section data below 2.25 keV, and the corresponding average parameters and covariance data were used in the present work as input for the statistical model analysis of the high energy range of the experimental data. The result of the analysis shows that the average resonance parameters obtained from the analysis of the unresolved resonance region are consistent with those obtained in the resolved energy region. Another important result is that ENDF/B-VI capture cross section could be too small by more than 10% in the energy range 10 keV to 200 keV.

  18. Neutron Total Cross Sections of {sup 235}U From Transmission Measurements in the Energy Range 2 keV to 300 keV and Statistical Model Analysis of the Data

    Energy Technology Data Exchange (ETDEWEB)

    Derrien, H.; Harvey, J.A.; Larson, N.M.; Leal, L.C.; Wright, R.Q.

    2000-05-01

    The average {sup 235}U neutron total cross sections were obtained in the energy range 2 keV to 330 keV from high-resolution transmission measurements of a 0.033 atom/b sample.1 The experimental data were corrected for the contribution of isotope impurities and for resonance self-shielding effects in the sample. The results are in very good agreement with the experimental data of Poenitz et al.4 in the energy range 40 keV to 330 keV and are the only available accurate experimental data in the energy range 2 keV to 40 keV. ENDF/B-VI evaluated data are 1.7% larger. The SAMMY/FITACS code 2 was used for a statistical model analysis of the total cross section, selected fission cross sections and data in the energy range 2 keV to 200 keV. SAMMY/FITACS is an extended version of SAMMY which allows consistent analysis of the experimental data in the resolved and unresolved resonance region. The Reich-Moore resonance parameters were obtained 3 from a SAMMY Bayesian fits of high resolution experimental neutron transmission and partial cross section data below 2.25 keV, and the corresponding average parameters and covariance data were used in the present work as input for the statistical model analysis of the high energy range of the experimental data. The result of the analysis shows that the average resonance parameters obtained from the analysis of the unresolved resonance region are consistent with those obtained in the resolved energy region. Another important result is that ENDF/B-VI capture cross section could be too small by more than 10% in the energy range 10 keV to 200 keV.

  19. Ordering and freezing-in phenomena of nanochannel water in crystalline organic/inorganic self-assembled complex [Cr(H2bim)3](TMA) x 23.5 H2O.

    Science.gov (United States)

    Watanabe, Keisuke; Oguni, Masaharu; Tadokoro, Makoto; Kobayashi, Chiho

    2009-10-29

    The thermal properties of crystalline complex [Cr(H(2)bim)(3)](TMA) x 23.5 H(2)O were studied by adiabatic calorimetry to clarify the structural ordering and dynamic freezing-in behaviors of the nanochannel water within the pores possessing crystalline wall structure, where H(2)bim denotes 2,2'-biimidazole and TMA is 1,3,5-benzenetricarboxylic acid. Phase and glass transitions were found to occur at 233 K with the associated entropy of Delta(trs)S = 7.96 J K(-1) mol(-1) and at T(g) = 100 K, respectively, in the hydrated sample. The phase transition was interpreted as attributed to the crystallization-like formation of the hydrogen-bond network of the channel-water molecules. The glass transition was interpreted as a freezing-in phenomenon on the way of the development of the network, and its presence indicates that the network formation achieves no completion even at 100 K. The T(g) value is similar to those found previously in other channel-water systems of [Ni(cyclam)(H(2)O)(2)](3)(TMA)(2) x 24 H(2)O and porous silica. It is noted that the channel water within silica pores with their diameter below 1.8 nm undergoes no structural phase transition while the present one does. The origins of the phase and glass transitions and the implication of their presence are discussed based on the difference in the structures of pore wall interacting with the channel-water molecules.

  20. 强流脉冲离子束辐照对金属玻璃Zr53Al23.5Cu5.9Co17.6结构和性能的影响%Effects on Structure and Properties of Zr53Al23.5Cu5.9Co17.6 Metallic Glass Irradiated by High Intensity Pulsed Ion Beam

    Institute of Scientific and Technical Information of China (English)

    赵晓云; 梅显秀; 刘小飞; 王英敏; 王友年

    2015-01-01

    利用强流脉冲离子束(High Intensity Pulsed Ion Beam,HIPIB)模拟核聚变装置中的瞬态高热负荷环境,离子束成分为Cn+(70%)和H+(30%)、加速电压为250 kV,研究金属玻璃Zr53Al23.5Cu5.9Co17.6和金属W在不同参数的HIPIB辐照下结构和性能的变化规律以及损伤行为。XRD显示辐照后金属玻璃均保持非晶相为主要结构,金属W中有应力产生。SEM观察在辐照次数为3和10次时金属玻璃和金属W表面都没有明显的辐照损伤现象;当辐照次数增加到100和300次后,金属玻璃表面出现了花瓣状形貌和小球,金属W表面则出现了裂纹。纳米压痕仪测量辐照后金属玻璃的表面纳米硬度随辐照次数的增加逐渐降低。Zr基金属玻璃具有较好的耐辐照性能,对HIPIB辐照时产生强的热应力的缓冲能力比金属W好。%High intensity pulsed ion beam(HIPIB) technology was used for simulating the transient heat load conditions of fusion reactor. The ion beam was mainly composed of Cn+(70%) and H+(30%) at an acceleration voltage of 250 kV. We investigated the changing rule of the structure and performance and damaged behavior of metallic glass Zr53Al23.5Cu5.9Co17.6 and W metal under different number of pulses. XRD analysis showed that the metallic glass remained making amorphous phase as its main structure after HIPIB irradiation, while stress were produced in W metal. SEM analysis concluded that there was no apparent irradiation damage on the surface of metallic glass and W metal when the irradiation frequency was 3 and 10 times. While the irradiation frequency increased to 100 and 300 times,“petal”-shaped and balls appeared on the surface of metallic glass, and cracks appeared on the surface of W. Nanoindentor showed that nano-hardness for the surface of metallic glass after irradiation reduced gradually with the increase of the frequency of irradiation. Zr-based metallic glass had a better resistance under HIPIB irradiation

  1. Energy Dependence of Fission Product Yields from 235U, 238U and 239Pu for Incident Neutron Energies Between 0.5 and 14.8 MeV

    Science.gov (United States)

    Gooden, M. E.; Arnold, C. W.; Becker, J. A.; Bhatia, C.; Bhike, M.; Bond, E. M.; Bredeweg, T. A.; Fallin, B.; Fowler, M. M.; Howell, C. R.; Kelley, J. H.; Krishichayan; Macri, R.; Rusev, G.; Ryan, C.; Sheets, S. A.; Stoyer, M. A.; Tonchev, A. P.; Tornow, W.; Vieira, D. J.; Wilhelmy, J. B.

    2016-01-01

    Fission Product Yields (FPY) have historically been one of the most observable features of the fission process. They are known to have strong variations that are dependent on the fissioning species, the excitation energy, and the angular momentum of the compound system. However, consistent and systematic studies of the variation of these FPY with energy have proved challenging. This is caused primarily by the nature of the experiments that have traditionally relied on radiochemical procedures to isolate specific fission products. Although radiochemical procedures exist that can isolate all products, each element presents specific challenges and introduces varying degrees of systematic errors that can make inter-comparison of FPY uncertain. Although of high importance in fields such as nuclear forensics and Stockpile Stewardship, accurate information about the energy dependence of neutron induced FPY are sparse, due primarily to the lack of suitable monoenergetic neutron sources. There is a clear need for improved data, and to address this issue, a collaboration was formed between Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL) and the Triangle Universities Nuclear Laboratory (TUNL) to measure the energy dependence of FPY for 235U, 238U and 239Pu. The measurements have been performed at TUNL, using a 10 MV Tandem Van de Graaff accelerator to produce monoenergetic neutrons at energies between 0.6 MeV to 14.8 MeV through a variety of reactions. The measurements have utilized a dual-fission chamber, with thin (10-100 μg/cm2) reference foils of similar material to a thick (100-400 mg) activation target held in the center between the chambers. This method allows for the accurate determination of the number of fissions that occurred in the thick target without requiring knowledge of the fission cross section or neutron fluence on target. Following activation, the thick target was removed from the dual-fission chamber and gamma

  2. Energy Dependence of Fission Product Yields from 235U, 238U and 239Pu for Incident Neutron Energies Between 0.5 and 14.8 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Gooden, M. E.; Arnold, C. W.; Becker, J. A.; Bhatia, C.; Bhike, M.; Bond, E. M.; Bredeweg, T. A.; Fallin, B.; Fowler, M. M.; Howell, C. R.; Kelley, J. H.; Krishichayan,; Macri, R.; Rusev, G.; Ryan, C.; Sheets, S. A.; Stoyer, M. A.; Tonchev, A. P.; Tornow, W.; Vieira, D. J.; Wilhelmy, J. B.

    2016-01-01

    Fission Product Yields (FPY) have historically been one of the most observable features of the fission process. They are known to have strong variations that are dependent on the fissioning species, the excitation energy, and the angular momentum of the compound system. However, consistent and systematic studies of the variation of these FPY with energy have proved challenging. This is caused primarily by the nature of the experiments that have traditionally relied on radiochemical procedures to isolate specific fission products. Although radiochemical procedures exist that can isolate all products, each element presents specific challenges and introduces varying degrees of systematic errors that can make inter-comparison of FPY uncertain. Although of high importance in fields such as nuclear forensics and Stockpile Stewardship, accurate information about the energy dependence of neutron induced FPY are sparse, due primarily to the lack of suitable monoenergetic neutron sources. There is a clear need for improved data, and to address this issue, a collaboration was formed between Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL) and the Triangle Universities Nuclear Laboratory (TUNL) to measure the energy dependence of FPY for 235U, 238U and 239Pu. The measurements have been performed at TUNL, using a 10 MV Tandem Van de Graaff accelerator to produce monoenergetic neutrons at energies between 0.6 MeV to 14.8 MeV through a variety of reactions. The measurements have utilized a dual-fission chamber, with thin (10-100 μg/cm2) reference foils of similar material to a thick (100-400 mg) activation target held in the center between the chambers. This method allows for the accurate determination of the number of fissions that occurred in the thick target without requiring knowledge of the fission cross section or neutron fluence on target. Following activation, the thick target was removed

  3. Dynamics of Cl (2Pj) atom formation in the photodissociation of fumaryl chloride (ClCO - CH = CH - COCl) at 235 nm: a resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) study.

    Science.gov (United States)

    Kawade, Monali; Saha, Ankur; Upadhyaya, Hari P; Kumar, Awadhesh; Naik, Prakash D; Bajaj, P N

    2011-03-10

    The photodissociation dynamics of fumaryl chloride (ClCO-CH═CH-COCl) has been studied in a supersonic molecular beam around 235 nm using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique by detecting the nascent state of the primary chlorine atom. A single laser has been used for excitation of fumaryl chloride and the REMPI detection of chlorine atoms in their spin-orbit states, Cl ((2)P(3/2)) and Cl* ((2)P(1/2)). We have determined the translational energy distribution, the recoil anisotropy parameter, β, and the spin-orbit branching ratio for chlorine atom elimination channels. To obtain these, measured polarization-dependent and state-specific TOF profiles are converted into kinetic energy distributions, using a least-squares fitting method, taking into account the fragment recoil anisotropies, β(i). The TOF profiles for both Cl and Cl* are found to be independent of laser polarization; i.e., β is well characterized by a value of 0.0, within the experimental uncertainties. Two components, namely, the fast and the slow, are observed in the translational energy distribution, P(E(T)), of Cl and Cl* atoms, and assigned to be formed from different potential energy surfaces. The average translational energies for the fast components of the Cl and Cl* channels are 14.9 ± 1.6 and 16.8 ± 1.6 kcal/mol, respectively. Similarly, for the slow components, the average translational energies of the Cl and Cl* channels are 3.4 ± 0.8 and 3.1 ± 0.8 kcal/mol, respectively. The energy partitioning into the translational modes is interpreted with the help of various models, such as impulsive and statistical models. Apart from the chlorine atom elimination channel, molecular hydrogen chloride (HCl) elimination is also observed in the photodissociation process. The HCl product has been detected, using a REMPI scheme in the region of 236-237 nm. The observation of the molecular HCl in the dissociation process highlights the importance of the

  4. ZPR-3 Assembly 11 : A cylindrical sssembly of highly enriched uranium and depleted uranium with an average {sup 235}U enrichment of 12 atom % and a depleted uranium reflector.

    Energy Technology Data Exchange (ETDEWEB)

    Lell, R. M.; McKnight, R. D.; Tsiboulia, A.; Rozhikhin, Y.; National Security; Inst. of Physics and Power Engineering

    2010-09-30

    Over a period of 30 years, more than a hundred Zero Power Reactor (ZPR) critical assemblies were constructed at Argonne National Laboratory. The ZPR facilities, ZPR-3, ZPR-6, ZPR-9 and ZPPR, were all fast critical assembly facilities. The ZPR critical assemblies were constructed to support fast reactor development, but data from some of these assemblies are also well suited for nuclear data validation and to form the basis for criticality safety benchmarks. A number of the Argonne ZPR/ZPPR critical assemblies have been evaluated as ICSBEP and IRPhEP benchmarks. Of the three classes of ZPR assemblies, engineering mockups, engineering benchmarks and physics benchmarks, the last group tends to be most useful for criticality safety. Because physics benchmarks were designed to test fast reactor physics data and methods, they were as simple as possible in geometry and composition. The principal fissile species was {sup 235}U or {sup 239}Pu. Fuel enrichments ranged from 9% to 95%. Often there were only one or two main core diluent materials, such as aluminum, graphite, iron, sodium or stainless steel. The cores were reflected (and insulated from room return effects) by one or two layers of materials such as depleted uranium, lead or stainless steel. Despite their more complex nature, a small number of assemblies from the other two classes would make useful criticality safety benchmarks because they have features related to criticality safety issues, such as reflection by soil-like material. ZPR-3 Assembly 11 (ZPR-3/11) was designed as a fast reactor physics benchmark experiment with an average core {sup 235}U enrichment of approximately 12 at.% and a depleted uranium reflector. Approximately 79.7% of the total fissions in this assembly occur above 100 keV, approximately 20.3% occur below 100 keV, and essentially none below 0.625 eV - thus the classification as a 'fast' assembly. This assembly is Fast Reactor Benchmark No. 8 in the Cross Section Evaluation

  5. Quantification of {sup 232}Th, {sup 234}U, {sup 235}U and {sup 238}U in river mollusks by magnetic sector mass spectrometry with inductively coupled plasma source (Icp-SFMS); Cuantificacion de {sup 232}Th, {sup 234}U, {sup 235}U y {sup 238}U en moluscos de rios por espectrometria de masas de sector magnetico con fuente de plasma acoplado inductivamente (ICP-SFMS)

    Energy Technology Data Exchange (ETDEWEB)

    Arevalo R, D. L.; Hernandez M, H.; Romero G, E. T.; Lara A, N. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Alfaro de la T, M. C., E-mail: arevalo0591@hotmail.com [Universidad Autonoma de San Luis Potosi, Dr. Salvador Nava s/n, Zona Universitaria, 78290 San Luis Potosi, SLP (Mexico)

    2016-09-15

    The present work deals with the methodology established for the quantification of {sup 232}Th, {sup 234}U, {sup 238}U and {sup 235}U in the shell of gastropod mollusks collected in the rivers Valles, Coy and Axtla of San Luis Potosi, Mexico, which belong to the Panuco River basin; these rivers have as main source of pollution the discharge of municipal sewage, waste from small industries, agricultural and cattle residues and from natural sources. Conventional methods for measuring radio-nuclides are confronted with certain conditions related to the requirement in measurement, basically in the characterization that is related to the concepts of precision and accuracy. The analysis of the gastropod mollusk shell was performed by the Icp-SFMS technique; the main advantages of this technique lie in the isotope quantification capacity, the high precision and the low limits of detection, in this study are very important because these elements are in concentrations between ppb and ppt. This technique allowed the analysis of the samples having a complex matrix by the presence CaCO{sub 3} minimizing the interferences thanks to the ionization efficiency of the Ar plasma. For the species Pachychilus monachus were found concentrations of {sup 232}Th of 0.16-5.37 μg/g and of total U of 0.101-4.081 μg/g being this species where the highest values of total U were found. For Thiara (melanoids) tuberculata the lowest values were found among the different species ({sup 232}Th 0.61-3.61 μg/g and total U 0.006-0.042 μg/g), for Pachychilus suturalis, values of {sup 232}Th of 0.58-6.4 μg/g and for Pachychilus sp. were found between 0.26-7.62 μg/g and for total U values between 0.28-3.33 μg/g. The method offers several advantages: speed, good precision, low values of quantification limits and high sensitivity in the measurement of radio-nuclides and heavy metals. (Author)

  6. Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy; Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie

    Energy Technology Data Exchange (ETDEWEB)

    Marx, Sebastian Markus

    2014-09-23

    The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.

  7. Production of actinium, thorium and radium isotopes from natural thorium irradiated with protons up to 141 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Ermolaev, S.V.; Zhuikov, B.L.; Kokhanyuk, V.M.; Matushko, V.L. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Research; Kalmykov, S.N. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Chemistry Dept.; Aliev, R.A. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Skobeltsyn Inst. of Nuclear Physics; Tananaev, I.G.; Myasoedov, B.F. [Russian Academy of Sciences, Moscow (Russian Federation). A.N. Frumkin Inst. of Physical Chemistry and Electrochemistry

    2012-07-01

    Cross sections of {sup 225}Ac, {sup 227}Ac, {sup 227}Th and {sup 228}Th in thorium-232 targets irradiated with protons in the energy range 21-141 MeV have been measured. Based on these data, production yields of {sup 225}Ac and {sup 223}Ra in thick thorium targets have been calculated. It is possible to produce in proton energy range 60-140 MeV about 96 GBq (2.6 Ci) {sup 225}Ac per 10-d irradiation with 100 {mu}A proton beam current and 10-d decay, and much higher amount of {sup 223}Ra. The impurities of {sup 227}Ac and {sup 224}Ra are important and need to be assessed for further medical applications. (orig.)

  8. Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J; O' Donoghue, J A; Humm, J L [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); Jaggi, J S [Bristol-Myers Squibb, Plainsboro, NJ (United States); Ruan, S; Larson, S M [Nuclear Medicine Service Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); McDevitt, M; Scheinberg, D A, E-mail: schwarj1@mskcc.org [Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065 (United States)

    2011-02-07

    Clinical therapeutic studies using {sup 225}Ac-labeled antibodies have begun. Of major concern is renal toxicity that may result from the three alpha-emitting progeny generated following the decay of {sup 225}Ac. The purpose of this study was to determine the amount of {sup 225}Ac and non-equilibrium progeny in the mouse kidney after the injection of {sup 225}Ac-huM195 antibody and examine the dosimetric consequences. Groups of mice were sacrificed at 24, 96 and 144 h after injection with {sup 225}Ac-huM195 antibody and kidneys excised. One kidney was used for gamma ray spectroscopic measurements by a high-purity germanium (HPGe) detector. The second kidney was used to generate frozen tissue sections which were examined by digital autoradiography (DAR). Two measurements were performed on each kidney specimen: (1) immediately post-resection and (2) after sufficient time for any non-equilibrium excess {sup 213}Bi to decay completely. Comparison of these measurements enabled estimation of the amount of excess {sup 213}Bi reaching the kidney ({gamma}-ray spectroscopy) and its sub-regional distribution (DAR). The average absorbed dose to whole kidney, determined by spectroscopy, was 0.77 (SD 0.21) Gy kBq{sup -1}, of which 0.46 (SD 0.16) Gy kBq{sup -1} (i.e. 60%) was due to non-equilibrium excess {sup 213}Bi. The relative contributions to renal cortex and medulla were determined by DAR. The estimated dose to the cortex from non-equilibrium excess {sup 213}Bi (0.31 (SD 0.11) Gy kBq{sup -1}) represented {approx}46% of the total. For the medulla the dose contribution from excess {sup 213}Bi (0.81 (SD 0.28) Gy kBq{sup -1}) was {approx}80% of the total. Based on these estimates, for human patients we project a kidney-absorbed dose of 0.28 Gy MBq{sup -1} following administration of {sup 225}Ac-huM195 with non-equilibrium excess {sup 213}Bi responsible for approximately 60% of the total. Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of {sup 225}Ac radioimmunotherapy.

  9. 一个同时携带线粒体DNA A1555G突变和GJB2235delC单杂合突变家系的基因型与听力表型%GJB2 235delC single allelic mutation modulates the phenotype associated with the mitochondrial A1555G mutation

    Institute of Scientific and Technical Information of China (English)

    李琦; 方如平; 周洪根; 戴朴; 田莉; 林镝; 黄群; 宋建敏

    2010-01-01

    Objective To investigate a non-syndromic deafness family in which potential interaction between the GJB2 gene and a mitochondrial gene appeared to be the cause of hearing impairment. Methods Audiological examination was performed by pure-tone audiometry (PTA). Blood samples from 8 members of the pedigree were obtained. DNA was extracted from the leukocytes. The coding region of the GJB2 gene and mitochondrial DNA target fragments were amplified by polymerase chain reaction (PCR). The PCR products were analyzed by sequencing. Results Direct sequencing showed that the proband had both a heterozygous mutation of 235delC in the GJB2 gene and a mitochondrial 1555 A to G mutation. The proband had profound hearing loss. The maternal relatives had sensorineural hearing loss in the higher frequencies or no hearing loss. Conclusion The GJB2 mutations may bean aggravating factor in the phenotypic expression of the non-syndromic hearing loss associated with the A1555G mitochondrial mutation.%目的 调查一个同时携带线粒体DNA A1555G突变和GJB2 235delC突变的非综合征型耳聋家系,分析其基因型和听力表型的关系.方法 对家系成员进行临床听力测试,收集家系中8名成员的外周静脉血样本,从白细胞中提取DNA,聚合酶链反应扩增GJB2基因和线粒体DNA(mitochondric DNA,mtDNA)目的 片段,对扩增片段直接测序进行GJB2基因、mtDNA 12S rRNA及tRNASer(UCN)基因突变分析.结果 此家系先证者存在mtDNA A1555G突变和GJB2 235delC杂合突变,听力表型为极重度感音神经性耳聋.其他母系成员携带mtDNA A1555G突变,未发现tRNASer(UCN)基因突变,家系中其他母系成员听力表型为双侧对称高频下降或听力正常.结论 GJB2 235delC单杂合突变可能参与了mtDNA A1555G的听力损害.

  10. In-Core Fuel Managements for PWRs: Investigation on solution for optimal utilization of PWR fuel through the use of fuel assemblies with differently enriched {sup 235}U fuel pins

    Energy Technology Data Exchange (ETDEWEB)

    Caprioli, Sara

    2004-04-01

    A possibility for more efficient use of the nuclear fuel in a pressurized water reactor is investigated. The alternative proposed here consists of the implementation of PWR fuel assemblies with differently enriched {sup 235}U fuel pins. This possibility is examined in comparison with the standard assembly design. The comparison is performed both in terms of single assembly performance and in the terms of nuclear reactor core performance and fuel utility. For the evaluation of the actual performance of the new assembly types, 5 operated fuel core sequences of R3 (Ringhals' third unit), for the period 1999 - 2004 (cycles 17 - 21) were examined. For every cycle, the standard fresh fuel assemblies have been identified and taken as reference cases for the study of the new type of assemblies with differently enriched uranium rods. In every cycle, assemblies with and without burnable absorber are freshly loaded into the core. The axial enrichment distribution is kept uniform, allowing for a radial (planar) enrichment level distribution only. At an assembly level, it has been observed that the implementation of the alternative enrichment configuration can lead to lower and flatter internal peaking factor distribution with respect to the uniformly enriched reference assemblies. This can be achieved by limiting the enrichment levels distribution to a rather narrow range. The highest enrichment level chosen has the greatest impact on the power distribution of the assemblies. As it increases, the enrichment level drives the internal peaking factor to greater values than in the reference assemblies. Generally, the highest enrichment level that would allow an improvement in the power performance of the assembly lies between 3.95 w/o and 4.17 w/o. The highest possible enrichment level depends on the average enrichment of the overall assembly, which is kept constant to the average enrichment of the reference assemblies. The improvements that can be obtained at this level are

  11. In-Core Fuel Managements for PWRs: Investigation on solution for optimal utilization of PWR fuel through the use of fuel assemblies with differently enriched {sup 235}U fuel pins

    Energy Technology Data Exchange (ETDEWEB)

    Caprioli, Sara

    2004-04-01

    A possibility for more efficient use of the nuclear fuel in a pressurized water reactor is investigated. The alternative proposed here consists of the implementation of PWR fuel assemblies with differently enriched {sup 235}U fuel pins. This possibility is examined in comparison with the standard assembly design. The comparison is performed both in terms of single assembly performance and in the terms of nuclear reactor core performance and fuel utility. For the evaluation of the actual performance of the new assembly types, 5 operated fuel core sequences of R3 (Ringhals' third unit), for the period 1999 - 2004 (cycles 17 - 21) were examined. For every cycle, the standard fresh fuel assemblies have been identified and taken as reference cases for the study of the new type of assemblies with differently enriched uranium rods. In every cycle, assemblies with and without burnable absorber are freshly loaded into the core. The axial enrichment distribution is kept uniform, allowing for a radial (planar) enrichment level distribution only. At an assembly level, it has been observed that the implementation of the alternative enrichment configuration can lead to lower and flatter internal peaking factor distribution with respect to the uniformly enriched reference assemblies. This can be achieved by limiting the enrichment levels distribution to a rather narrow range. The highest enrichment level chosen has the greatest impact on the power distribution of the assemblies. As it increases, the enrichment level drives the internal peaking factor to greater values than in the reference assemblies. Generally, the highest enrichment level that would allow an improvement in the power performance of the assembly lies between 3.95 w/o and 4.17 w/o. The highest possible enrichment level depends on the average enrichment of the overall assembly, which is kept constant to the average enrichment of the reference assemblies. The improvements that can be obtained at this level are

  12. 2,9-Dimethyl-1,10-phenanthrolin-1-ium (6-carboxy-4-hydroxypyridine-2-carboxylato-κ3O2,N,O6(4-hydroxypyridine-2,6-dicarboxylato-κ3O2,N,O6zincate(II 2.35-hydrate: a proton-transfer compound

    Directory of Open Access Journals (Sweden)

    Zohreh Derikvand

    2012-01-01

    Full Text Available In the title compound, (C14H13N2[Zn(C7H3NO5(C7H4NO5]·2.35H2O, the ZnII atom is coordinated by two N atoms and four O atoms from the carboxylate groups of the 4-hydroxypyridine-2,6-dicarboxylate and 6-carboxy-4-hydroxypyridine-2-carboxylate ligands, forming a distored octahedral geometry. In the anion, the two pyridine rings are inclined to one another by 87.75 (13°. Two types of robust O—H...O hydrogen bond synthons, viz. R22(16 and R66(42, link the anions to form a two-dimensional network parallel to the bc plane. Furthermore, O—H...O, N—H...O, N—H...N and weak C—H...O hydrogen bonds connect the two dimensional networks, forming a three-dimensional structure. In the crystal, there are also C—H...π and π–π interactions [centroid–centroid distances of 3.5554 (18 and 3.7681 (18 Å], and C=O...π interactions [O...centroid distance = 3.117 (2 Å] present. One of the three crystal water molecules shows an occupancy of 0.35.

  13. 41 CFR 101-4.235 - Statutory amendments.

    Science.gov (United States)

    2010-07-01

    ... legal abortion. Accordingly, subject to paragraph (d)(1) of this section, no person shall be excluded... received, or is seeking, a legal abortion, or any benefit or service related to a legal abortion. ... abortion. Medical procedures, benefits, services, and the use of facilities, necessary to save the life of...

  14. 48 CFR 952.235-71 - Research misconduct.

    Science.gov (United States)

    2010-10-01

    ... investigation. Investigation means the formal examination and evaluation of the relevant facts. Plagiarism means.... Research misconduct means fabrication, falsification, or plagiarism in proposing, performing, or reviewing...

  15. 48 CFR 1252.235-70 - Research misconduct.

    Science.gov (United States)

    2010-10-01

    .... Plagiarism is the appropriation of another person's ideas, processes, results, or words without giving... means fabrication, falsification, or plagiarism, in proposing, performing, or reviewing research, or in...

  16. Dicty_cDB: AFG235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available se. 86 2e-65 11 BD183626 |BD183626.1 Material for diagnosing malaria and immune antigen for suppressing growth of plasmodium.... 76 1e-57 9 BD183625 |BD183625.1 Material for diagnosing malaria and immune antigen for suppressing growth of plasmo...dium. 76 1e-57 9 AB026051 |AB026051.1 Plasmodium falcipa

  17. Dicty_cDB: SHF235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Lactuca sativa cDNA cloneQGC21B24, mRNA sequence. 80 1e-12 2 BH165696 |BH165696.1 ENTTP28TR Entamoeba histolytica Shear...8 |BH164508.1 ENTTD23TF Entamoeba histolytica Sheared DNA Entamoeba histolytica genomic, DNA sequence. 68 5e...-07 1 BH163900 |BH163900.1 ENTSJ80TR Entamoeba histolytica Sheared DNA Entamoeba histolytica genomic, DNA se...quence. 68 5e-07 1 BH148907 |BH148907.1 ENTPE41TR Entamoeba histolytica Sheared DNA Entamoeba histolytica ge...nomic, DNA sequence. 68 5e-07 1 BH163033 |BH163033.1 ENTRP52TR Entamoeba histolytica Shear

  18. Dicty_cDB: AFF235 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 3 CK420742 |CK420742.1 AUF_IpTrk_27_j08 Trunk kidney cDNA library Ictalurus punctatus cDNA 5' similar to ER-resident... chaperone calreticulin, mRNA sequence. 56 6e-04 1 AY342298 |AY342298.1 Ictalurus punctatus ER-resident

  19. 235-IJBCS-Article-Prof G R Kassenga

    African Journals Online (AJOL)

    RHUMSIKI

    Arsenic contamination levels in drinking water sources in mining areas in. Lake Victoria Basin ... arsenic poisoning include burning and dryness of the mouth and throat, ... measure needed is to prevent further exposure of population by ...

  20. 8 CFR 235.3 - Inadmissible aliens and expedited removal.

    Science.gov (United States)

    2010-01-01

    ... right to consult with other persons prior to the interview and any review thereof at no expense to the United States Government; (C) The right to request a review by an immigration judge of the asylum officer... unreasonably delay the process. (5) Claim to lawful permanent resident, refugee, or asylee status or U.S...