WorldWideScience

Sample records for actinium 227

  1. Production of high-purity radium-223 from legacy actinium-beryllium neutron sources.

    Soderquist, Chuck Z; McNamara, Bruce K; Fisher, Darrell R

    2012-07-01

    Radium-223 is a short-lived alpha-particle-emitting radionuclide with potential applications in cancer treatment. Research to develop new radiopharmaceuticals employing (223)Ra has been hindered by poor availability due to the small quantities of parent actinium-227 available world-wide. The purpose of this study was to develop innovative and cost-effective methods to obtain high-purity (223)Ra from (227)Ac. We obtained (227)Ac from two surplus actinium-beryllium neutron generators. We retrieved the actinium/beryllium buttons from the sources and dissolved them in a sulfuric-nitric acid solution. A crude actinium solid was recovered from the solution by coprecipitation with thorium fluoride, leaving beryllium in solution. The crude actinium was purified to provide about 40 milligrams of actinium nitrate using anion exchange in methanol-water-nitric acid solution. The purified actinium was then used to generate high-purity (223)Ra. We extracted (223)Ra using anion exchange in a methanol-water-nitric acid solution. After the radium was separated, actinium and thorium were then eluted from the column and dried for interim storage. This single-pass separation produces high purity, carrier-free (223)Ra product, and does not disturb the (227)Ac/(227)Th equilibrium. A high purity, carrier-free (227)Th was also obtained from the actinium using a similar anion exchange in nitric acid. These methods enable efficient production of (223)Ra for research and new alpha-emitter radiopharmaceutical development.

  2. Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes.

    Radchenko, V; Engle, J W; Wilson, J J; Maassen, J R; Nortier, F M; Taylor, W A; Birnbaum, E R; Hudston, L A; John, K D; Fassbender, M E

    2015-02-06

    Actinium-225 (t1/2=9.92d) is an α-emitting radionuclide with nuclear properties well-suited for use in targeted alpha therapy (TAT), a powerful treatment method for malignant tumors. Actinium-225 can also be utilized as a generator for (213)Bi (t1/2 45.6 min), which is another valuable candidate for TAT. Actinium-225 can be produced via proton irradiation of thorium metal; however, long-lived (227)Ac (t1/2=21.8a, 99% β(-), 1% α) is co-produced during this process and will impact the quality of the final product. Thus, accurate assays are needed to determine the (225)Ac/(227)Ac ratio, which is dependent on beam energy, irradiation time and target design. Accurate actinium assays, in turn, require efficient separation of actinium isotopes from both the Th matrix and highly radioactive activation by-products, especially radiolanthanides formed from proton-induced fission. In this study, we introduce a novel, selective chromatographic technique for the recovery and purification of actinium isotopes from irradiated Th matrices. A two-step sequence of cation exchange and extraction chromatography was implemented. Radiolanthanides were quantitatively removed from Ac, and no non-Ac radionuclidic impurities were detected in the final Ac fraction. An (225)Ac spike added prior to separation was recovered at ≥ 98%, and Ac decontamination from Th was found to be ≥ 10(6). The purified actinium fraction allowed for highly accurate (227)Ac determination at analytical scales, i.e., at (227)Ac activities of 1-100 kBq (27 nCi to 2.7 μCi).

  3. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

    Henriksen, Gjermund; Bruland, Oyvind S; Larsen, Roy H

    2004-01-01

    The present study explores the use of alpha-particle-emitting, bone-seeking agents as candidates for targeted radiotherapy. Actinium and thorium 1,4,7,10 tetraazacyclododecane N,N',N'',N''' 1,4,7,10-tetra(methylene) phosphonic acid (DOTMP) and thorium-diethylene triamine N,N',N'' penta(methylene) phosphonic acid (DTMP) were prepared and their biodistribution evaluated in conventional Balb/C mice at four hours after injection. All three bone-seeking agents showed a high uptake in bone and a low uptake in soft tissues. Among the soft tissue organs, only kidney had a relatively high uptake. The femur/kidney ratios for 227Th-DTMP, 228-Ac-DOTMP and 227Th-DOTMP were 14.2, 7.6 and 6.0, respectively. A higher liver uptake of 228Ac-DOTMP was seen than for 227Th-DTMP and 227Th-DOTMP. This suggests that some demetallation of the 228Ac-DOTMP complex had occurred. The results indicate that 225Ac-DOTMP, 227Th-DOTMP and 227Th-DTMP have promising properties as potential therapeutic bone-seeking agents.

  4. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    Fry, C

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  5. Spectroscopic and computational investigation of actinium coordination chemistry

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac–Cl and Ac–OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1– ligands (3.2±1.1) than AmIII (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour. PMID:27531582

  6. Spectroscopic and computational investigation of actinium coordination chemistry

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-08-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1- ligands (3.2+/-1.1) than AmIII (0.8+/-0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour.

  7. Relativistic small-core pseudopotentials for actinium, thorium, and protactinium.

    Weigand, Anna; Cao, Xiaoyan; Hangele, Tim; Dolg, Michael

    2014-04-03

    Small-core pseudopotentials for actinium, thorium, and protactinium have been energy-adjusted to multiconfiguration Dirac-Hartree-Fock reference data based on the Dirac-Coulomb-Breit Hamiltonian and the Fermi nucleus model. Corresponding optimized valence basis sets of polarized valence quadruple-ζ quality are presented. Atomic test calculations for the first four ionization potentials show satisfactory results at both the Hartree-Fock and the multireference averaged coupled-pair functional level. Highly correlated Fock-space coupled cluster calculations demonstrate that the new pseudopotentials yield ionization potentials, which are in excellent agreement with corresponding all-electron results and experimental data. The pseudopotentials and basis sets supplement a similar set previously published for uranium.

  8. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  9. Proposition 227: What Now?

    Ward, Ben

    1998-01-01

    Provides background on and discusses the significance of Proposition 227, the California ballot initiative designed to reform the state's bilingual-education program that was approved by voters in 1998. Reactions to its approval by California voters are provided by Ron Unz, Stephen Krashen, and Mauro Mujica. (Author/VWL)

  10. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    Momeni, M.H.

    1981-09-01

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore.

  11. AAS 227: Day 1

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or at astrobites.com, or catch ourlive-tweeted updates from the @astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Things kicked off last night at our undergraduate reception booth. Thanks to all of you who stopped by we were delightedto have so many people tell us that they already know about and useastrobites, and we were excited to introduce a new cohort of students at AAS to astrobites for the first time.Tuesday morning was the official start of the meeting. Here are just a few of the talks and workshops astrobiters attended today.Opening Address (by Becky Smethurst)The President of the AAS, aka our fearless leader Meg Urry kicked off the meeting this morning at the purely coffee powered hour of 8am this morning. She spoke about the importance of young astronomers at the meeting (heres looking at you reader!) and also the importance of the new Working Group for Accessibility and Disabilities (aka WGAD pronounced like wicked) at the AAS. The Society has made extra effort this year to make the conference accessible to all,a message which was very well received by everyone in attendance.Kavli Lecture: New Horizons Alan Stern (by Becky Smethurst)We were definitely spoilt with the first Plenary lecture at this years conference Alan Stern gave us a a review of the New Horizons mission of the Pluto Fly By (astrobites covered the mission back in July with this post). We were treated to beautiful images, wonderful results and a foray into geology.Before (Hubble) and after #NewHorizons. #thatisall #science #astro alanstern #aas227 pic.twitter.com/kkMt6RsSIR Science News (@topsciencething) January 5, 2016Some awesome facts from the lecture that blew my mind:New Horizons is now 2AU (!) beyond Pluto

  12. AAS 227: Day 3

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Welcome to Day 3 of the winter American Astronomical Society (AAS) meeting in Kissimmee! Several of us are attending the conference this year, and we will report highlights from each day here on astrobites. If youd like to see more timely updates during the day, we encourage you to follow @astrobites on twitter or search the #aas227 hashtag.Henry Norris Russell Lecture: Viewing the Universe with Infrared Eyes: The Spitzer Space Telescope (by Erika Nesvold)The Henry Norris Russell Award is the highest honor given by the AAS, for a lifetime of eminence in astronomy research. This years award went to Giovanni Fazio of the Harvard-Smithsonian Center for Astrophysics. Fazio became a leader in gamma ray astronomy before switching mid-career to the study of infrared astronomy, and he gave his award lecture on the latter subject, specifically on the Spitzer Space Telescope, one of the most successful infrared telescopes of all time.Artists rendering of the Spitzer space telescope. [NASA/JPL-Caltech]Spitzer has been operating for more than twelve years, and has resulted in over six thousand papers in refereed journals in that time. The telescope sits in an Earth-trailing orbit around the Sun, and is now farther from the Earth (1.4 AU) than the Earth is from the Sun. Fazio gave the audience a fascinating overview of the science done by Spitzer over more than a decade. One of the most productive areas of research for Spitzer is the study of exoplanets, which hadnt even been discovered when the Spitzer Telescope was first conceived. Spitzers high sensitivity and ability to observe exoplanets over

  13. AAS 227: Day 4

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Welcome to Day 4 of the winter American Astronomical Society (AAS) meeting in Kissimmee! Several of us are attending the conference this year, and we will report highlights from each day here on astrobites. If youd like to see more timely updates during the day, we encourage you to follow @astrobites on twitter or search the #aas227 hashtag.Helen B. Warner Prize: Origins of Structure in Planetary Systems (by Erika Nesvold)Another excellent prize lecture started off todays sessions. The Helen B. Warner Prize is awarded for achievement in observational or theoretical astrophysics by a young researcher (no more than eight years after their Ph.D.). This years Warner Prize was presented to Ruth Murray-Clay of UC Santa Barbara. For her award lecture, Murray-Clay told us all about planetary system architecture: the number, masses, and orbits of planets in a given system.Ruth Murray-Clay [photo from http://web.physics.ucsb.edu/ ~murray/biocv.html]The underlying question motivating this type of research is: How rare is the Solar System? In other words, how likely is it that a given planetary system will have rocky planets close to their star, gas giants farther out, and ice giants at the outer reaches of the system? Answering this question will help us solve the physics problem of how and where planets form, and will also help us on our search for other planets like Earth.The data on exoplanet population from transit and radial velocity observations and from direct imaging tell us that our Solar System is not common (many systems we observe have much more eccentric gas giants), but that doesnt

  14. AAS 227: Day 2

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Welcome to Day 2 of the winter American Astronomical Society (AAS) meeting in Kissimmee! Several of us are attending the conference this year, and we will report highlights from each day here on astrobites. If youd like to see more timely updates during the day, we encourage you to follow @astrobites on twitter or search the #aas227 hashtag.Plenary Session: Black Hole Physics with the Event Horizon Telescope (by Susanna Kohler)If anyone needed motivation to wake up early this morning, they got it in the form of Feryal Ozel (University of Arizona) enthralling us all with exciting pictures, videos, and words about black holes and the Event Horizon Telescope. Ozel spoke to a packed room (at 8:30am!) about where the project currently stands, and where its heading in the future.The EHT has pretty much the coolest goal ever: actually image the event horizons of black holes in our universe. The problem is that the largest black hole we can look at (Sgr A*, in the center of our galaxy) has an event horizon size of 50 as. For this kind of resolution roughly equivalent to trying to image a DVD on the Moon! wed need an Earth-sized telescope. EHT has solved this problem by linking telescopes around the world, creating one giant, mm-wavelength effective telescope with a baseline the size of Earth.Besides producing awesome images, the EHT will be able to test properties of black-hole spacetime, the no-hair theorem, and general relativity (GR) in new regimes.Ozel walked us through some of the theory prep work we need to do now in order to get the most science out of the EHT, including devising new

  15. AAS 227: Welcome!

    Kohler, Susanna

    2016-01-01

    Greetings from the 227th American Astronomical Society meeting in Kissimmee, Florida! This week, along with several fellow authors from astrobites, Iwill bewritingupdates on selectedevents at themeeting and posting at the end of each day. You can follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.If youre an author or referee (or plan to be!) and youre here at the meeting, consider joining us at our Author and Referee Workshop on Wednesday in the Tallahassee room, where well be sharingsome of the exciting new features of the AAS journals. You can drop intoeither of the two-hour sessions(10 AM 12 PM or 1 PM 3 PM), and there will be afree buffet lunch at noon.Heres the agenda:Morning SessionTopic Speaker10:00 am 10:05 amIntroductionsJulie Steffen10:05 am 10:35 amChanges at AAS Journals; How to Be a Successful AAS AuthorEthan Vishniac10:35 am 11:00 amThe Peer Review ProcessButler Burton11:00 am 11:15 amAAS Nova: Sharing AAS Authors Research with the Broader CommunitySusanna Kohler11:15 am 11:30 amFixing Software and Instrumentation Publishing: New Paper Styles in AAS JournalsChris Lintott11:30 am 11:45 amMaking Article Writing Easier with the New AASTeX v6.0Greg Schwarz11:45 am 12:00 pmBringing JavaScript and Interactivity to Your AAS Journal FiguresGus MuenchLunch SessionTopic Speaker12:00 pm 12:15 pmUnified Astronomy ThesaurusKatie Frey12:15 pm 12:30 pmAAS/ADS ORCID Integration ToolAlberto Accomazzi12:30 pm 12:45 pmWorldWide Telescope and Video AbstractsJosh Peek12:45 pm 01:00 pmArizona Astronomical Data Hub (AADH)Bryan HeidornAfternoon SessionTopic Speaker01:00 pm 01:05 pmIntroductionsJulie Steffen01:05 pm 01:35 pmChanges at AAS Journals; How to Be a Successful AAS AuthorEthan Vishniac01:35 pm 02:00 pmThe Peer Review ProcessButler Burton02:00 pm 02:15 pmAAS Nova: Sharing AAS Authors Research with the Broader CommunitySusanna Kohler02:15 pm 02:30 pm

  16. 50 CFR 600.227 - Lobbying.

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Lobbying. 600.227 Section 600.227 Wildlife..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Council Membership § 600.227 Lobbying. (a) Council... Commerce implementing regulations published at 15 CFR part 28, “New Restrictions on Lobbying.”...

  17. 49 CFR 238.227 - Suspension system.

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Suspension system. 238.227 Section 238.227 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Equipment § 238.227 Suspension system. On or after November 8, 1999— (a) All passenger equipment...

  18. 33 CFR 136.227 - Proof.

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Proof. 136.227 Section 136.227 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE POLLUTION... SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.227 Proof. In addition to...

  19. 7 CFR 227.5 - Program funding.

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Program funding. 227.5 Section 227.5 Agriculture... CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.5 Program funding. (a... agencies shall maintain their present level of funding for existing nutrition education and...

  20. 25 CFR 227.23 - Wells.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Wells. 227.23 Section 227.23 Indians BUREAU OF INDIAN... RESERVATION, WYOMING, FOR OIL AND GAS MINING Operations § 227.23 Wells. The lessee shall agree (a) to drill and produce all wells necessary to offset or protect the leased land from drainage by wells...

  1. 7 CFR 227.3 - Administration.

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 227.3 Section 227.3 Agriculture... CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.3 Administration. (a) Within the Department, FNS shall act on behalf of the Department in the administration of the Program....

  2. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Raeder, S., E-mail: s.raeder@gsi.de [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Bastin, B. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Block, M. [Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Institut für Kernchemie, Johannes Gutenberg Universität, 55128 Mainz (Germany); Creemers, P. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Delahaye, P. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Ferrer, R. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fléchard, X. [LPC Caen, ENSICAEN, Université de Caen, CNRS/IN2P3, Caen (France); Franchoo, S. [Institute de Physique Nucléaire (IPN) d’Orsay, 91406 Orsay, Cedex (France); Ghys, L. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); SCK-CEN, Belgian Nuclear Research Center, Boeretang 200, 2400 Mol (Belgium); Gaffney, L.P.; Granados, C. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Heinke, R. [Institut für Physik, Johannes Gutenberg Universität, 55128 Mainz (Germany); Hijazi, L. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); and others

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  3. 49 CFR 227.115 - Hearing protectors.

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Hearing protectors. 227.115 Section 227.115 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad...

  4. 30 CFR 22.7 - Specific requirements.

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Specific requirements. 22.7 Section 22.7 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING, EVALUATION, AND... on a wood floor from a height of 3 feet. Parts that are strapped to the user may be subjected to...

  5. 27 CFR 44.227 - Customs procedure.

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Customs procedure. 44.227..., WITHOUT PAYMENT OF TAX, OR WITH DRAWBACK OF TAX Drawback of Tax § 44.227 Customs procedure. The customs... having inspected the articles and supervised the lading thereof on the export carrier, the...

  6. 36 CFR 223.227 - Sale advertisement.

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Sale advertisement. 223.227... DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Special Forest Products Advertisement and Bids § 223.227 Sale advertisement. (a) The Forest Service shall advertise any special forest products sales with an appraised...

  7. Dicty_cDB: VHI227 [Dicty_cDB

    Full Text Available VH (Link to library) VHI227 (Link to dictyBase) - - - Contig-U16260-1 VHI227P (Link to Original site) VHI2...27F 617 VHI227Z 710 VHI227P 1307 - - Show VHI227 Library VH (Link to library) Clone ID VHI2...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VH/VHI2-B/VHI227Q.Seq.d/ Representative seq. ID VHI2...27P (Link to Original site) Representative DNA sequence >VHI227 (VHI227Q) /CSM/VH/VHI2-B/VHI2...DNA clone:ddv63k21, 3' ... 1382 0.0 1 ( BJ446797 ) Dictyostelium discoideum cDNA clone:ddv63i24, 3' ... 1382

  8. 25 CFR 227.19 - Division orders.

    2010-04-01

    ... INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING Rents and Royalties § 227.19 Division orders. (a... it to the supervisor for his consideration. The right is reserved for the supervisor to cancel...

  9. 7 CFR 227.2 - Definitions.

    2010-01-01

    ... CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM General § 227.2 Definitions. (a... section 17 of the National School Lunch Act, as amended. (c) Child Nutrition Programs means any or all of... of the Child Nutrition Act of 1966, as amended. (n) School means: (1) An educational unit of...

  10. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    Rakhimov, A.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz); Warot, G. [CEA-CNRS, Modane (France). Laboratoire Souterrain de Modane (LSM); Karaivanov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Institute for Nuclear Research and Nuclear Energy (INRNE), Sofia (Bulgaria); Kochetov, O.I.; Lebedev, N.A.; Filosofov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Mukhamedshina, N.M.; Sadikov, I.I. [Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz)

    2013-07-01

    A technique of selenium purification from {sup 232}Th, {sup 238}U, {sup 226,228}Ra, {sup 227}Ac and {sup 40}K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  11. 22 CFR Appendix A to Part 227 - Certification Regarding Lobbying

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certification Regarding Lobbying A Appendix A to Part 227 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NEW RESTRICTIONS ON LOBBYING Pt. 227, App. A Appendix A to Part 227—Certification Regarding Lobbying Certification for...

  12. 34 CFR 300.227 - Direct services by the SEA.

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Direct services by the SEA. 300.227 Section 300.227... CHILDREN WITH DISABILITIES Local Educational Agency Eligibility § 300.227 Direct services by the SEA. (a) General. (1) An SEA must use the payments that would otherwise have been available to an LEA or to a...

  13. 48 CFR 252.227-7004 - License grant.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License grant. 252.227... Clauses 252.227-7004 License grant. As prescribed at 227.7009-3(a), insert the following clause in patent releases, license agreements, and assignments: License Grant (AUG 1984) (a) The Contractor hereby grants...

  14. 48 CFR 252.227-7005 - License term.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License term. 252.227-7005... Clauses 252.227-7005 License term. As prescribed at 227.7009-3(b), insert one of the following clauses in patent releases, license agreements, and assignments: License Term (OCT 2001) Alternate I (AUG 1984)....

  15. 48 CFR 2453.227 - Patents, data, and copyrights.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Patents, data, and copyrights. 2453.227 Section 2453.227 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CLAUSES AND FORMS FORMS Prescription of Forms 2453.227 Patents, data, and copyrights....

  16. 25 CFR 227.6 - Corporations and corporate information.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Corporations and corporate information. 227.6 Section 227... § 227.6 Corporations and corporate information. (a) If the applicant for a lease is a corporation, it... the lands are located, evidence showing compliance with the corporation laws thereof. Statements...

  17. Production of actinium, thorium and radium isotopes from natural thorium irradiated with protons up to 141 MeV

    Ermolaev, S.V.; Zhuikov, B.L.; Kokhanyuk, V.M.; Matushko, V.L. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Research; Kalmykov, S.N. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Chemistry Dept.; Aliev, R.A. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Skobeltsyn Inst. of Nuclear Physics; Tananaev, I.G.; Myasoedov, B.F. [Russian Academy of Sciences, Moscow (Russian Federation). A.N. Frumkin Inst. of Physical Chemistry and Electrochemistry

    2012-07-01

    Cross sections of {sup 225}Ac, {sup 227}Ac, {sup 227}Th and {sup 228}Th in thorium-232 targets irradiated with protons in the energy range 21-141 MeV have been measured. Based on these data, production yields of {sup 225}Ac and {sup 223}Ra in thick thorium targets have been calculated. It is possible to produce in proton energy range 60-140 MeV about 96 GBq (2.6 Ci) {sup 225}Ac per 10-d irradiation with 100 {mu}A proton beam current and 10-d decay, and much higher amount of {sup 223}Ra. The impurities of {sup 227}Ac and {sup 224}Ra are important and need to be assessed for further medical applications. (orig.)

  18. 48 CFR 1552.227-76 - Project employee confidentiality agreement.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Project employee confidentiality agreement. 1552.227-76 Section 1552.227-76 Federal Acquisition Regulations System ENVIRONMENTAL... electrical services, provisions which shall conform substantially to the language of this clause,...

  19. 25 CFR 227.22 - Diligence and prevention of waste.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Diligence and prevention of waste. 227.22 Section 227.22... prevention of waste. The lessee shall exercise diligence in drilling and operating wells for oil and gas on... prevention of waste of oil or gas developed on the land, or the entrance of water through wells drilled...

  20. 12 CFR 227.25 - Unfair balance computation method.

    2010-01-01

    ... under 12 CFR 226.12 or 12 CFR 226.13; or (2) Adjustments to finance charges as a result of the return of... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Unfair balance computation method. 227.25... Practices Rule § 227.25 Unfair balance computation method. (a) General rule. Except as provided in...

  1. 25 CFR 227.12 - Mineral reserves in nonmineral entries.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Mineral reserves in nonmineral entries. 227.12 Section 227.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire...

  2. 42 CFR 93.227 - Secretary or HHS.

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Secretary or HHS. 93.227 Section 93.227 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  3. 14 CFR 125.227 - Cockpit voice recorders.

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Cockpit voice recorders. 125.227 Section... Requirements § 125.227 Cockpit voice recorders. (a) No certificate holder may operate a large turbine engine... cockpit voice recorder is installed in that airplane and is operated continuously from the start of...

  4. 48 CFR 227.7203-4 - License rights.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License rights. 227.7203-4... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The... license, under an irrevocable license granted or obtained by the contractor which developed the...

  5. 48 CFR 227.7103-4 - License rights.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License rights. 227.7103-4... 227.7103-4 License rights. (a) Grant of license. The Government obtains rights in technical data, including a copyright license, under and irrevocable license granted or obtained for the Government by...

  6. 20 CFR 227.2 - Initial supplemental annuity rate.

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Initial supplemental annuity rate. 227.2... COMPUTING SUPPLEMENTAL ANNUITIES § 227.2 Initial supplemental annuity rate. The supplemental annuity rate, before reduction for the railroad retirement family maximum or any private pension, is $23 for...

  7. 48 CFR 227.7203-5 - Government rights.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Government rights. 227..., DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights...

  8. 48 CFR 1952.227-77 - Rights in shop drawings.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Rights in shop drawings. 1952.227-77 Section 1952.227-77 Federal Acquisition Regulations System BROADCASTING BOARD OF GOVERNORS... Rights in shop drawings. As prescribed in 1927.405(h), insert the following clause: Rights in...

  9. 48 CFR 52.227-3 - Patent Indemnity.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Patent Indemnity. 52.227-3... AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52.227-3 Patent Indemnity. As prescribed in 27.201-2(c)(1), insert the following clause: Patent Indemnity (APR 1984) (a)...

  10. 12 CFR 22.7 - Forced placement of flood insurance.

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Forced placement of flood insurance. 22.7... HAVING SPECIAL FLOOD HAZARDS § 22.7 Forced placement of flood insurance. If a bank, or a servicer acting... or mobile home and any personal property securing the designated loan is not covered by...

  11. 13 CFR 134.227 - Finality of decisions.

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Finality of decisions. 134.227 Section 134.227 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION RULES OF PROCEDURE GOVERNING... decisions. (a) Initial decisions. Except as otherwise provided in paragraph (b) of this section, a...

  12. 7 CFR 227.43 - Participation of adults.

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Participation of adults. 227.43 Section 227.43 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM Miscellaneous §...

  13. Research on Transport Properties of HFC-227ea

    Lin Shi; Xiaojun Liu; Yuanyuan Duan; Lizhong Han; Mingshan Zhu

    2001-01-01

    HFC-227ea(1,1,1,2,3,3,3-heptafluoropropane) is considered as a promising refrigerant alternative, especially as a component in mixtures, to replace to CFC-12, HCFC-22 and R502. But reliable transport properties data for HFC-227ea are very limited. In this paper, experimental data of viscosity along the saturation line and gaseous thermal conductivity of HFC-227ea are given. The viscosity of HFC-227ea was measured with a capillary viscometer at temperatures between 263.15 K and 333.15 K along the saturation line and its uncertainty of the results is estimated to be no more than +3%. The thermal conductivity of gaseous HFC-227ea was also measured with a transient hot-wire instrument at temperatures between 259.28 K and 341.75 K and pressures up to 1.289MPa, and its uncertainty of the results is estimated to be less than +1%.

  14. Canadair CL-227 Remotely Piloted Vehicle

    Clark, Andrew S.

    1983-08-01

    The Canadair CL-227 is a rotary winged Remotely Piloted Vehicle (RPV) intended initially as the air-vehicle for a medium range battlefield surveillance and target acquisition system. The concept on which this vehicle is based brings together in-house expertise as a designer and manufacturer of surveillance drones (AN-USD-50l -MIDGE-) with experience in rigid rotor technology from the CL-84 tilt wing VTOL program. The vehicle is essentially modular in design with a power module containing the engine, fuel and related systems, a rotor module containing the two counter-rotating rotors and control actuators, and a control module containing the autopilot, data link and sensor system. The vehicle is a true RPV (as opposed to a drone) as it is flown in real time by an operator on the ground and requires relatively little skill to pilot.

  15. 18 CFR 284.227 - Certain transportation by intrastate pipelines.

    2010-04-01

    ... Interstate Pipelines on Behalf of Others and Services by Local Distribution Companies § 284.227 Certain... interstate pipeline or local distribution company served by an interstate pipeline. (e) Pregrant...

  16. 40 CFR 227.19 - Assessment of impact.

    2010-07-01

    ... Dumping on Esthetic, Recreational and Economic Values § 227.19 Assessment of impact. An overall assessment... on the effect on esthetic, recreational and economic values based on the factors set forth in this... profitability of other commercial enterprises....

  17. 49 CFR 227.117 - Hearing protector attenuation.

    2010-10-01

    ... exposure to an 8-hour TWA of 90 decibels or lower, as required by § 227.115. (c) For employees who have...-weighted average of 85 decibels or lower. (d) The adequacy of hearing protector attenuation shall be...

  18. 49 CFR 227.113 - Noise operational controls.

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating Employees. § 227.113 Noise operational controls. (a) Railroads may use noise operational controls at any sound level to reduce exposures to levels below those required by Table A-1 of appendix A...

  19. 49 CFR 227.107 - Hearing conservation program.

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating Employees. § 227.107 Hearing conservation program. (a) Consistent with the requirements of the... exposure shall be computed in accordance with the tables in appendix A of this part, and without regard...

  20. 49 CFR 227.111 - Audiometric test requirements.

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating Employees. § 227.111 Audiometric test requirements. (a) Audiometric tests shall be pure tone, air... with 5 U.S.C. 552(a) and 1 CFR part 51. You may obtain a copy of the incorporated standard from...

  1. 48 CFR 1852.227-70 - New technology.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true New technology. 1852.227-70... New technology. As prescribed in 1827.303-70(b), insert the following clause: New Technology (NOV 1998... administration of this New Technology clause within six months of conception and/or first actual reduction...

  2. 49 CFR 234.227 - Train detection apparatus.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION GRADE CROSSING SIGNAL SYSTEM SAFETY AND STATE ACTION PLANS Maintenance, Inspection, and Testing Maintenance Standards § 234.227 Train detection apparatus. (a) Train detection apparatus shall be maintained to detect a train or railcar in any part of a train detection circuit,...

  3. 49 CFR 227.101 - Scope and applicability.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating Employees. § 227.101 Scope and applicability. (a) This subpart shall apply to the noise-related working... service laws governing “train employees” (see 49 U.S.C. 21101(5) and 21103), but, subject to a...

  4. 7 CFR 227.35 - Responsibilities of State coordinator.

    2010-01-01

    ... 227.35 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM State Coordinator... implementation of the State Plan, (f) Coordination of the Program with the Child Nutrition Programs at the...

  5. 40 CFR 227.31 - Applicable marine water quality criteria.

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Applicable marine water quality... § 227.31 Applicable marine water quality criteria. Applicable marine water quality criteria means the criteria given for marine waters in the EPA publication “Quality Criteria for Water” as published in...

  6. 20 CFR 227.4 - Reduction for employer pension.

    2010-04-01

    ... COMPUTING SUPPLEMENTAL ANNUITIES § 227.4 Reduction for employer pension. (a) General. The supplemental annuity for each month is reduced by the amount of any private pension the employee is receiving for that... annuity amount after any reduction for railroad retirement family maximum. Private pension is explained...

  7. 20 CFR 227.5 - Employer tax credits.

    2010-04-01

    ... SUPPLEMENTAL ANNUITIES § 227.5 Employer tax credits. Employers are entitled to tax credits if they pay non-negotiated pensions to former employees whose supplemental annuities are reduced because of the pensions. Non-negotiated pensions are paid under pension plans that are not established by collective bargaining...

  8. 40 CFR 227.30 - High-level radioactive waste.

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false High-level radioactive waste. 227.30...-level radioactive waste. High-level radioactive waste means the aqueous waste resulting from the operation of the first cycle solvent extraction system, or equivalent, and the concentrated waste...

  9. 50 CFR 665.227 - Allowable gear and gear restrictions.

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Allowable gear and gear restrictions. 665... Fisheries § 665.227 Allowable gear and gear restrictions. (a) Hawaii coral reef ecosystem MUS may be taken only with the following allowable gear and methods: (1) Hand harvest; (2) Spear; (3) Slurp gun;...

  10. 48 CFR 1952.227-76 - Government rights (unlimited).

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Government rights... 1952.227-76 Government rights (unlimited). As prescribed in 1927.405(g), insert the following clause: Government Rights (Unlimited) (FEB 1985) The Government shall have unlimited rights, in all drawings,...

  11. 48 CFR 1852.227-84 - Patent rights clauses.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Patent rights clauses. 1852... 1852.227-84 Patent rights clauses. The contracting officer shall insert the following provision as prescribed in 1827.303-70(e): Patent Rights Clauses (DEC 1989) This solicitation contains the patent...

  12. 48 CFR 3452.227-72 - Advertising of awards.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Advertising of awards... Clauses 3452.227-72 Advertising of awards. As prescribed in 3427.472, insert the following clause in all solicitations and contracts other than purchase orders: Advertising of Awards (AUG 1987) The contractor...

  13. 40 CFR 227.27 - Limiting permissible con-cen-tra-tion (LPC).

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Limiting permissible con-cen-tra-tion (LPC). 227.27 Section 227.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Definitions § 227.27 Limiting permissible con-cen-tra-tion (LPC). (a) The limiting permissible...

  14. 22 CFR Appendix B to Part 227 - Disclosure Form To Report Lobbying

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Disclosure Form To Report Lobbying B Appendix B to Part 227 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NEW RESTRICTIONS ON LOBBYING Pt. 227, App. B Appendix B to Part 227—Disclosure Form To Report Lobbying EC06OC91.012...

  15. 48 CFR 227.7103-12 - Government right to establish conformity of markings.

    2010-10-01

    ... establish conformity of markings. 227.7103-12 Section 227.7103-12 Federal Acquisition Regulations System..., DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-12 Government right to establish conformity of... correct the nonconformity and return the corrected data within 60 days following the person's receipt...

  16. 40 CFR 227.10 - Hazards to fishing, navigation, shorelines or beaches.

    2010-07-01

    ..., shorelines or beaches. 227.10 Section 227.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Environmental Impact § 227.10 Hazards to fishing, navigation, shorelines or beaches. (a) Wastes which may... present a hazard to shorelines or beaches may be dumped only at sites and under conditions which...

  17. 30 CFR 227.301 - What are a State's responsibilities if it performs audits?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What are a State's responsibilities if it performs audits? 227.301 Section 227.301 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Functions § 227.301 What are a State's responsibilities if it performs audits? If you perform audits...

  18. 48 CFR 252.227-7038 - Patent Rights-Ownership by the Contractor (Large Business).

    2010-10-01

    ... Contractor (Large Business). As prescribed in 227.303(2), use the following clause: Patent Rights—Ownership... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Patent Rights-Ownership by the Contractor (Large Business). 252.227-7038 Section 252.227-7038 Federal Acquisition...

  19. 40 CFR 227.16 - Basis for determination of need for ocean dumping.

    2010-07-01

    ... ocean dumping. 227.16 Section 227.16 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS Need for Ocean Dumping § 227.16 Basis for determination of need for ocean dumping. (a) A need for...

  20. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    2010-10-01

    ... Business Innovation Research (SBIR) Program. 227.7104 Section 227.7104 Federal Acquisition Regulations... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or... PATENTS, DATA, AND COPYRIGHTS Rights in Technical Data 227.7104 Contracts under the Small...

  1. 48 CFR 52.227-10 - Filing of Patent Applications-Classified Subject Matter.

    2010-10-01

    ... Applications-Classified Subject Matter. 52.227-10 Section 52.227-10 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.227-10 Filing of Patent Applications—Classified Subject Matter. As prescribed at 27.203-2, insert the following clause: Filing of Patent Applications—Classified Subject...

  2. 40 CFR 227.32 - Liquid, suspended particulate, and solid phases of a material.

    2010-07-01

    ... MATERIALS Definitions § 227.32 Liquid, suspended particulate, and solid phases of a material. (a) For the... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Liquid, suspended particulate, and solid phases of a material. 227.32 Section 227.32 Protection of Environment ENVIRONMENTAL...

  3. 48 CFR 1852.227-14 - Rights in data-General.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Rights in data-General. 1852.227-14 Section 1852.227-14 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE... 1852.227-14 Rights in data—General. As prescribed in 1827.409(a), add the following subparagraph (3)...

  4. 25 CFR 227.14 - Government reserves right to purchase oil and gas.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Government reserves right to purchase oil and gas. 227.14... CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire Leases § 227.14 Government reserves right to purchase oil and gas. In time of war or other public emergency...

  5. 48 CFR 227.7206 - Contracts for architect-engineer services.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contracts for architect... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services....

  6. 48 CFR 227.7009-3 - Additional clauses-contracts except running royalty contracts.

    2010-10-01

    ...-contracts except running royalty contracts. 227.7009-3 Section 227.7009-3 Federal Acquisition Regulations...—contracts except running royalty contracts. The following clauses are examples for use in patent release and settlement agreements, and license agreements not providing for payment by the Government of a...

  7. 48 CFR 252.227-7006 - License grant-running royalty.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License grant-running... of Provisions And Clauses 252.227-7006 License grant—running royalty. As prescribed at 227.7009-4(a...—Running Royalty (AUG 1984) (a) The Contractor hereby grants to the Government, as represented by...

  8. 48 CFR 252.227-7007 - License term-running royalty.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false License term-running... of Provisions And Clauses 252.227-7007 License term—running royalty. As prescribed at 227.7009-4(b), insert the following clause in patent releases, license agreements, and assignments: License...

  9. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    2010-10-01

    ... establish conformity of markings. 227.7203-12 Section 227.7203-12 Federal Acquisition Regulations System... Government right to establish conformity of markings. (a) Nonconforming markings. (1) Authorized markings are... expense. If that person fails to correct the nonconformity and return the corrected software...

  10. 30 CFR 227.108 - How will MMS notify a State of its decision?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS notify a State of its decision? 227.108 Section 227.108 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR... of its decision? MMS will notify you in writing of its decision on your delegation proposal. If...

  11. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Commercial computer software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation...

  12. 25 CFR 227.10 - Minerals other than oil and gas.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Minerals other than oil and gas. 227.10 Section 227.10... Minerals other than oil and gas. Unreserved, unwithdrawn, and unallotted lands which have not been leased... therefor, are subject to mineral application or mineral entry, for minerals other than oil and gas,...

  13. 48 CFR 252.227-7012 - Patent license and release contract.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Patent license and release... of Provisions And Clauses 252.227-7012 Patent license and release contract. As prescribed at 227.7012, insert the following clause in patent releases, license agreements, and assignments: (Contract...

  14. 48 CFR 252.227-7039 - Patents-reporting of subject inventions.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Patents-reporting of... CLAUSES Text of Provisions And Clauses 252.227-7039 Patents—reporting of subject inventions. As prescribed in 227.303(1), use the following clause: Patents—Reporting of Subject Inventions (APR 1990)...

  15. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    2010-10-01

    ... container and each page, or portions thereof, of printed material containing computer software for which... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation....

  16. 7 CFR 227.37 - State plan for nutrition education and training.

    2010-01-01

    ...) Plans, including a timetable, for reaching all children in the State with instruction in the nutritional... 7 Agriculture 4 2010-01-01 2010-01-01 false State plan for nutrition education and training. 227... PROGRAM State Coordinator Provisions § 227.37 State plan for nutrition education and training. (a)...

  17. 30 CFR 227.401 - What are a State's responsibilities if it processes production reports or royalty reports?

    2010-07-01

    ... processes production reports or royalty reports? 227.401 Section 227.401 Mineral Resources MINERALS...' Responsibilities to Perform Delegated Functions § 227.401 What are a State's responsibilities if it processes production reports or royalty reports? In processing production reports or royalty reports you must:...

  18. 40 CFR 227.14 - Criteria for evaluating the need for ocean dumping and alternatives to ocean dumping.

    2010-07-01

    ... ocean dumping and alternatives to ocean dumping. 227.14 Section 227.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) OCEAN DUMPING CRITERIA FOR THE EVALUATION OF PERMIT APPLICATIONS FOR OCEAN DUMPING OF MATERIALS Need for Ocean Dumping § 227.14 Criteria for evaluating the need for...

  19. In vivo detection of prion amyloid plaques using [{sup 11}C]BF-227 PET

    Okamura, Nobuyuki; Yanai, Kazuhiko [Tohoku University School of Medicine, Department of Pharmacology, Sendai (Japan); Shiga, Yusei; Itoyama, Yasuhito [Tohoku University School of Medicine, Department of Neurology, Sendai (Japan); Furumoto, Shozo [Tohoku University School of Medicine, Department of Pharmacology, Sendai (Japan); Tohoku University, Division of Radiopharmaceutical Chemistry, Cyclotron and Radioisotope Center, Sendai (Japan); Tashiro, Manabu [Tohoku University, Division of Cyclotron Nuclear Medicine, Cyclotron and Radioisotope Center, Sendai (Japan); Tsuboi, Yoshio [Fukuoka University School of Medicine, Department of Neurology, Fukuoka (Japan); Furukawa, Katsutoshi; Arai, Hiroyuki [Institute of Development, Aging, and Cancer, Tohoku University, Department of Geriatrics and Gerontology, Division of Brain Sciences, Sendai (Japan); Iwata, Ren [Tohoku University, Division of Radiopharmaceutical Chemistry, Cyclotron and Radioisotope Center, Sendai (Japan); Kudo, Yukitsuka [Tohoku University, Innovation of New Biomedical Engineering Center, Sendai (Japan); Doh-ura, Katsumi [Tohoku University School of Medicine, Department of Prion Research, 2-1 Seiryo-machi, Aoba-ku, Sendai (Japan)

    2010-05-15

    In vivo detection of pathological prion protein (PrP) in the brain is potentially useful for the diagnosis of transmissible spongiform encephalopathies (TSEs). However, there are no non-invasive ante-mortem means for detection of pathological PrP deposition in the brain. The purpose of this study is to evaluate the amyloid imaging tracer BF-227 with positron emission tomography (PET) for the non-invasive detection of PrP amyloid in the brain. The binding ability of BF-227 to PrP amyloid was investigated using autoradiography and fluorescence microscopy. Five patients with TSEs, including three patients with Gerstmann-Straeussler-Scheinker disease (GSS) and two patients with sporadic Creutzfeldt-Jakob disease (CJD), underwent [{sup 11}C]BF-227 PET scans. Results were compared with data from 10 normal controls and 17 patients with Alzheimer's disease (AD). The regional to pons standardized uptake value ratio was calculated as an index of BF-227 retention. Binding of BF-227 to PrP plaques was confirmed using brain samples from autopsy-confirmed GSS cases. In clinical PET study, significantly higher retention of BF-227 was detected in the cerebellum, thalamus and lateral temporal cortex of GSS patients compared to that in the corresponding tissues of normal controls. GSS patients also showed higher retention of BF-227 in the cerebellum, thalamus and medial temporal cortex compared to AD patients. In contrast, the two CJD patients showed no obvious retention of BF-227 in the brain. Although [{sup 11}C]BF-227 is a non-specific imaging marker of cerebral amyloidosis, it is useful for in vivo detection of PrP plaques in the human brain in GSS, based on the regional distribution of the tracer. PET amyloid imaging might provide a means for both early diagnosis and non-invasive disease monitoring of certain forms of TSEs. (orig.)

  20. Surgical intervention for advanced valvular heart disease in 227 cases

    ZHANG Xi; ZHONG Fo-tian; XU Zhe; XU Ying-qi; WANG Zhi-ping; WU Zhong-kai; TANG Bai-yun; XIONG Mai; YAO Jian-ping; SUN Pei-wu

    2005-01-01

    Background Although the results of surgical treatment in cardiac valve disease continue to improve, the postoperative mortality rate and the rate of complications in patients with advanced valvular heart disease (AVHD) are still very high. We did this retrospective study to summarize the surgical experience of heart valve replacement for patients with AVHD and discuss effective ways to improve the surgical outcome.Results The operative mortality rate was 13.2% (30/227). The main causes of death included multiple organ dysfunction syndrome (MODS), low cardiac output syndrome and ventricular fibrillation. From the results of the binary noncounterpart multivariate logistic regression, the following statistically significant factors were found to influence the operative mortality rate: redo operation, age ≥55 years, preoperative NYHA cardiac function grading, extracorporeal circulation time ≥120 minutes and postoperative usage of GIK (glucose, insulin and potassium) solution. All factors were risk ones except postoperative application of GIK. The Hosmer-Lemeshow goodness of fit coefficient of this model was 0.976.Conclusions The risk factors associated with postoperative mortality rate in the patients with AVHD were redo operation, age ≥55 years, preoperative NYHA cardiac function grading and extracorporeal circulation time ≥120 minutes. Postoperative usage of GIK acted as a kind of metabolic therapy and will improve the recovery for patients with AVHD. Active perioperative management and care will play a very important role in reducing the operative risk and improving the short term outcome of surgical treatment for the patients with AVHD.

  1. Malus pumila 'Spy 227' and Apple stem pitting virus: graft incompatibility and epinasty.

    Brakta, Ajay; Handa, Anil; Thakur, P D; Tomar, Manica; Kumar, Pardeep

    2015-06-01

    Apple stem pitting foveavirus (ASPV) is one of the most important and widespread virus infecting apples in the world. Of late, the virus has been found to be invariably associated with most of the apple plantations of Shimla district of Himachal Pradesh based on DAS-ELISA results. Bioassay of viruses in vegetatively propagated crops including apple is considered to be an essential component in indexing programmes for the production of virus free propagating material. Woody indicator Malus pumila 'Spy 227' was used for the detection of ASPV through double grafting method. Graft incompatibility and epinasty symptoms were observed on Malus pumila Spy 227 indicator plants. Further, molecular identification of the virus isolate was done by cloning and sequencing of the test isolate. Partial sequence analysis of the coat protein gene showed 89 % nucleotide identity in BLASTN analysis with ASPV isolate from China (Accession No. JF895517). This is the first record of ASPV producing Graft incompatibility on Spy 227 indicator plants.

  2. Extraction and purification of {sup 227}Ac and development of solid {sup 219}Rn source

    Tang, Quan; Qiu, Shoukang; Xiao, Detao; Zhou, Yaohui; An, Xiaogang [University of South China, Hengyang (China). Radon Key Laboratory of Hunan Province/School of Nuclear Science and Technology

    2014-04-01

    The method of {sup 227}Ac extraction and purification from high-grade uranium ore and the test results of solid {sup 219}Rn source made from {sup 227}Ac are reported in this paper. With five years of follow-up monitoring, radiochemical purity of {sup 227}Ac and the emanation power of solid {sup 219}Rn source has been checked by emanation method and γ-spectrometry, the results showed that {sup 228}Th, {sup 231}Pa and {sup 226}Ra have been effectively removed and the emanation power of {sup 219}Rn source is about 80%. The long-term test results also showed that the {sup 219}Rn emanation rate remains stable in a wide air humidity range (40% ∝ 90%). Though the {sup 219}Rn source has not been accurately calibrated yet, it has been applied in the research for delay coincidence measurement of {sup 223}Ra. (orig.)

  3. 48 CFR 227.7009-4 - Additional clauses-contracts providing for payment of a running royalty.

    2010-10-01

    ...-contracts providing for payment of a running royalty. 227.7009-4 Section 227.7009-4 Federal Acquisition... clauses—contracts providing for payment of a running royalty. The clauses set forth below are examples... desired to cover the subject matter thereof and the contract provides for payment of a running royalty....

  4. 49 CFR 173.227 - Materials poisonous by inhalation, Division 6.1, Packing Group I, Hazard Zone B.

    2010-10-01

    ..., Packing Group I, Hazard Zone B. 173.227 Section 173.227 Transportation Other Regulations Relating to..., Packing Group I, Hazard Zone B. (a) In packagings as authorized in § 173.226 and seamless and welded... conform to the performance test requirements of subpart M of part 178 of this subchapter at the...

  5. 48 CFR 227.7107 - Contracts for architect-engineer services.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contracts for architect... Rights in Technical Data 227.7107 Contracts for architect-engineer services. This section sets forth... of construction and architect-engineer services....

  6. 30 CFR 227.102 - What royalty management functions will MMS not delegate?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What royalty management functions will MMS not... MINERALS REVENUE MANAGEMENT DELEGATION TO STATES Delegation of Mms Royalty Functions § 227.102 What royalty management functions will MMS not delegate? This section lists the principal royalty management...

  7. 30 CFR 227.101 - What royalty management functions may MMS delegate to a State?

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What royalty management functions may MMS... THE INTERIOR MINERALS REVENUE MANAGEMENT DELEGATION TO STATES Delegation of Mms Royalty Functions § 227.101 What royalty management functions may MMS delegate to a State? (a) If there are oil and...

  8. 25 CFR 227.4 - Sale of oil and gas leases.

    2010-04-01

    ... BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEASING OF CERTAIN LANDS IN WIND RIVER INDIAN RESERVATION, WYOMING, FOR OIL AND GAS MINING How to Acquire Leases § 227.4 Sale of oil and... sales of oil and gas leases shall reserve to the Secretary of the Interior the right to reject all...

  9. 25 CFR 227.25 - Inspection of premises, books and accounts.

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Inspection of premises, books and accounts. 227.25... Inspection of premises, books and accounts. Lessee shall agree to allow the lessor and his agents or any... Department; and their books and records, showing manner of operations and persons interested, shall be...

  10. An ISO far-infrared survey of line and continuum emission for 227 galaxies

    Brauher, J. R.

    2002-01-01

    Far-infrared line and continuum fluxes are presented for a sample of 227 galaxies observed with the Long Wavelength Spectrometer on the Infrared Space Observatory, selected from the ISO Data Archive and having an IRAS 60/100 mu m color ration of 0.2-1.4 and IRAS 60 mu m flux density between 0.1 Jy and 1300 Jy.

  11. 48 CFR 227.7103-14 - Conformity, acceptance, and warranty of technical data.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Conformity, acceptance..., DATA, AND COPYRIGHTS Rights in Technical Data 227.7103-14 Conformity, acceptance, and warranty of... requirements of the contract pertaining to the delivery of technical data. (b) Conformity and acceptance....

  12. The Political Discourse of the Campaign against Bilingual Education: From "Proposition 227" to "Horne v. Flores"

    Yamagami, Mai

    2012-01-01

    Using the frameworks of critical discourse analysis, representation theory, and legitimization theory, this study examines the political discourse of the campaign for Proposition 227 in California--particularly, the key social representations of languages, their speakers, and the main political actors in the campaign. The analysis examines the…

  13. Jesu, meine Freude BWV 227 van Johann Sebastian Bach : een praedicatio sonora

    Eikelboom, Arie

    2007-01-01

    In the oeuvre of Johann Sebastian Bach the motets take only a modest position. According to Bach's early biographers he must have written many motets, but only few have been preserved. Among these motets Jesu, meine Freude BWV 227 occupies a special position. It is the only one which combines a comp

  14. 48 CFR 1852.227-85 - Invention reporting and rights-Foreign.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Invention reporting and... Provisions and Clauses 1852.227-85 Invention reporting and rights—Foreign. As prescribed in 1827.303-70(f), insert the following clause: Invention Reporting and Rights—Foreign (APR 1986) (a) As used in this...

  15. 48 CFR 3053.227-70 - Conveyance of invention rights acquired by the Government.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Conveyance of invention... Prescription of Forms 3053.227-70 Conveyance of invention rights acquired by the Government. The following form is prescribed for including a means for contractors to report inventions made in the course...

  16. 48 CFR 52.227-7 - Patents-Notice of Government Licensee.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Patents-Notice of... Clauses 52.227-7 Patents—Notice of Government Licensee. As prescribed at 27.202-5(b), insert the following provision: Patents—Notice of Government Licensee (APR 1984) The Government is obligated to pay a...

  17. 48 CFR 227.7009 - Patent releases, license agreements, and assignments.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Patent releases, license... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Infringement Claims, Licenses, and Assignments 227.7009 Patent releases, license agreements,...

  18. 48 CFR 52.227-4 - Patent Indemnity-Construction Contracts.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Patent Indemnity... Clauses 52.227-4 Patent Indemnity—Construction Contracts. As prescribed in 27.201-2(d)(1), insert the following clause: Patent Indemnity—Construction Contracts (DEC 2007) Except as otherwise provided,...

  19. Initial evaluation of {sup 227}Th-p-benzyl-DOTA-rituximab for low-dose rate {alpha}-particle radioimmunotherapy

    Dahle, Jostein [Department of Radiation Biology, Rikshospitalet-Radiumhospitalet HE, Montebello, 0310 Oslo (Norway)]. E-mail: jostein.dahle@labmed.uio.no; Borrebaek, Jorgen [Algeta ASA, Kjelsasveien 172 A, 0411 Oslo (Norway); Melhus, Katrine B. [Department of Radiation Biology, Rikshospitalet-Radiumhospitalet HE, Montebello, 0310 Oslo (Norway); Bruland, Oyvind S. [Department of Clinical Medicine, University of Oslo, 0316 Oslo (Norway); Department of Oncology, Rikshospitalet-Radiumhospitalet HE, Montebello, 0310 Oslo (Norway); Salberg, Gro [Algeta ASA, Kjelsasveien 172 A, 0411 Oslo (Norway); Olsen, Dag Rune [Department of Radiation Biology, Rikshospitalet-Radiumhospitalet HE, Montebello, 0310 Oslo (Norway); Larsen, Roy H. [Algeta ASA, Kjelsasveien 172 A, 0411 Oslo (Norway)

    2006-02-15

    Radioimmunotherapy has proven clinically effective in patients with non-Hodgkin's lymphoma. Radioimmunotherapy trials have so far been performed with {beta}-emitting isotopes. In contrast to {beta}-emitters, the shorter range and high linear energy transfer (LET) of {alpha} particles allow for more efficient and selective killing of individually targeted tumor cells. However, there are several obstacles to the use of {alpha}-particle immunotherapy, including problems with chelation chemistry and nontarget tissue toxicity. The {alpha}-emitting radioimmunoconjugate {sup 227}Th-DOTA-p-benzyl-rituximab is a new potential anti-lymphoma agent that might overcome some of these difficulties. The present study explores the immunoreactivity, in vivo stability and biodistribution, as well as the effect on in vitro cell growth, of this novel radioimmunoconjugate. To evaluate in vivo stability, uptake in balb/c mice of the {alpha}-particle-emitting nuclide {sup 227}Th alone, the chelated form, {sup 227}Th-p-nitrobenzyl-DOTA and the radioimmunoconjugate {sup 227}Th-DOTA-p-benzyl-rituximab was compared in a range of organs at increasing time points after injection. The immunoreactive fraction of {sup 227}Th-DOTA-p-benzyl-rituximab was 56-65%. During the 28 days after injection of radioimmunoconjugate only, very modest amounts of the {sup 227}Th had detached from DOTA-p-benzyl-rituximab, indicating a relevant stability in vivo. The half-life of {sup 227}Th-DOTA-p-benzyl-rituximab in blood was 7.4 days. Incubation of lymphoma cells with {sup 227}Th-DOTA-p-benzyl-rituximab resulted in a significant antigen-dependent inhibition of cell growth. The data presented here warrant further studies of {sup 227}Th-DOTA-p-benzyl-rituximab.

  20. DIRECT LIQUEFACTION PROOF-OF-CONCEPT PROGRAM - BENCH RUN PB-10 (HTI 227-109)

    Unknown

    1999-12-30

    This report presents the results of the bench-scale test, PB-10, performed at HTI's facilities under DOE contract (HTI Run No. 227-109). This bench test continues the work that was started in PDU testing 260-007. Previous bench test (PB-09, HTI 227-106) was performed on different seams of Chinese coal (Shenhua Ningtiaota Coal No.2 and No.3). Since another coal, Shangwan coal was selected for the liquefaction plant, PB-10 was made as approved by DOE/COR. The objective of this test was to evaluate the liquefaction performance of Shangwan coal utilizing various backend processing and recycle schemes. Additionally, this test was to collect available process data to allow for the best scale-up process design possible from this particular unit.

  1. Human Cystathionine-β-Synthase Phosphorylation on Serine227 Modulates Hydrogen Sulfide Production in Human Urothelium.

    Roberta d'Emmanuele di Villa Bianca

    Full Text Available Urothelium, the epithelial lining the inner surface of human bladder, plays a key role in bladder physiology and pathology. It responds to chemical, mechanical and thermal stimuli by releasing several factors and mediators. Recently it has been shown that hydrogen sulfide contributes to human bladder homeostasis. Hydrogen sulfide is mainly produced in human bladder by the action of cystathionine-β-synthase. Here, we demonstrate that human cystathionine-β-synthase activity is regulated in a cGMP/PKG-dependent manner through phosphorylation at serine 227. Incubation of human urothelium or T24 cell line with 8-Bromo-cyclic-guanosine monophosphate (8-Br-cGMP but not dibutyryl-cyclic-adenosine monophosphate (d-cAMP causes an increase in hydrogen sulfide production. This result is congruous with the finding that PKG is robustly expressed but PKA only weakly present in human urothelium as well as in T24 cells. The cGMP/PKG-dependent phosphorylation elicited by 8-Br-cGMP is selectively reverted by KT5823, a specific PKG inhibitor. Moreover, the silencing of cystathionine-β-synthase in T24 cells leads to a marked decrease in hydrogen sulfide production either in basal condition or following 8-Br-cGMP challenge. In order to identify the phosphorylation site, recombinant mutant proteins of cystathionine-β-synthase in which Ser32, Ser227 or Ser525 was mutated in Ala were generated. The Ser227Ala mutant cystathionine-β-synthase shows a notable reduction in basal biosynthesis of hydrogen sulfide becoming unresponsive to the 8-Br-cGMP challenge. A specific antibody that recognizes the phosphorylated form of cystathionine-β-synthase has been produced and validated by using T24 cells and human urothelium. In conclusion, human cystathionine-β-synthase can be phosphorylated in a PKG-dependent manner at Ser227 leading to an increased catalytic activity.

  2. Interplay of fission modes in mass distribution of light actinide nuclei 225,227Pa

    R. Dubey

    2016-01-01

    Full Text Available Fission-fragment mass distributions were measured for 225,227Pa nuclei formed in fusion reactions of 19F+206,208Pb around fusion barrier energies. Mass-angle correlations do not indicate any quasi-fission like events in this bombarding energy range. Mass distributions were fitted by Gaussian distribution and mass variance extracted. At below-barrier energies, the mass variance was found to increase with decrease in energy for both nuclei. Results from present work were compared with existing data for induced fission of 224,226Th and 228U around barrier energies. Enhancement in mass variance of 225,227Pa nuclei at below-barrier energies shows evidence for presence of asymmetric fission events mixed with symmetric fission events. This is in agreement with the results of mass distributions of nearby nuclei 224,226Th and 228U where two-mode fission process was observed. Two-mode feature of fission arises due to the shell effects changing the landscape of the potential-energy surfaces at low excitation energies. The excitation-energy dependence of the mass variance gives strong evidence for survival of microscopic shell effects in fission of light actinide nuclei 225,227Pa with initial excitation energy ∼30–50 MeV.

  3. RE170、RE170/R227ea与矿物油的互溶性评价%Miscibility evaluation of RE170 and RE170/R227ea with a mineral oil

    田田; 杨昭; 吴曦; 余壮壮

    2015-01-01

    Refrigerant R22 is scheduled to be phased out and new and environmentally friendly refrigerants RE170 and RE170/R227ea have promising application. Miscibility of these refrigerants with lubricants has a large influence on working effect of the refrigerating system. For this reason, an experimental apparatus for testing miscibility of new refrigerants with lubricants was established based on standard SH/T 0699—2000. The miscibility values of promising refrigerants RE170 and mixed refrigerant RE170/R227ea with a mineral oil were studied. RE170 and the mineral oil were completely miscible at−50℃, as oil proportion changed from 10%to 60%. When R227ea mass fraction in mixed refrigerant RE170/R227ea changed from 35% to 60% and oil proportion was specified at 14.6%±0.5%, low phase separation temperature increased with increasing R227ea. When R227ea mass fraction was below 38%, the mixed refrigerant and mineral oil became miscible even at−50℃. When R227ea mass fraction was over 55%, the mixed refrigerant and mineral oil were immiscible even at room temperature. Finally, by combining the methods of empirical equation and solubility parameter, a new evaluation method was proposed to evaluate the miscibility of pure refrigerants and binary refrigerant mixtures with the mineral oil.%随着制冷剂R22逐步淘汰,RE170、RE170/R227ea新型环保制冷剂有应用前景,其和润滑油能否互溶直接影响制冷系统的使用效果。根据标准SH/T 0699—2000建立了一套制冷剂和润滑油的互溶性测试系统,对RE170、RE170/R227ea和矿物油的互溶性进行了试验研究。结果表明:RE170的矿物油溶液在含油率为10%~60%时,当温度低至−50℃时没有出现分层或絮状物,二者互溶性非常好;混合制冷剂RE170/R227ea的矿物油溶液在含油率为14.6%±0.5%的基准情况下,当R227ea的质量分数在35%~60%变动时RE170/R227ea和矿物油的低温两相分离温度随R227ea含量增加而

  4. Interplay of fission modes in mass distribution of light actinide nuclei 225,227Pa

    Dubey, R; Jhingan, A; Kaur, Gurpreet; Mukul, Ish; Mohanto, G; Siwal, D; Saneesh, N; Banerjee, T; Thakur, Meenu; Mahajan, Ruchi; Kumar, N; Chatterjee, M B

    2015-01-01

    Fission-fragment mass distributions were measured for 225,227Pa nuclei formed in fusion reactions of 19F + 206, 208Pb around fusion barrier energies. Mass-angle correlations do not indicate any quasi-fission like events in this bombarding energy range. Mass distributions were fitted by Gaussian distribution and mass variance extracted. At below-barrier energies, the mass variance was found to increase with decrease in energy for both nuclei. Results from present work were compared with existing data for induced fission of 224, 226Th and 228U around barrier energies. Enhancement in mass variance of 225, 227Pa nuclei at below-barrier energies shows evidence for presence of asymmetric fission events mixed with symmetric fission events. This is in agreement with the results of mass distributions of nearby nuclei 224, 226Th and 228U where two-mode fission process was observed. Two-mode feature of fission arises due to the shell effects changing the landscape of the potential energy surfaces at low excitation energ...

  5. A compiled catalogue of reference stars around 227 ICRF extragalactic radio sources.

    Ryl'kov, V. P.; Narizhnaya, N. V.; Dement'eva, A. A.; Pinigin, G. I.; Maigurova, N. V.; Martinov, M. V.

    A compiled catalogue of21440 stars with magnitudes from 10 to 17 is prepared on the basis of original observations made from the end of the 20th to the beginning of the 21th century. The catalogue con tains 227 fields of the cetes tial sphere around extragalactic radio sources in a declination zone from -17 to +89°. The field size is 40' for both right ascension and declination. The internal accuracy of positions for both coordinates is not worse than 0.1". The comparison of stellar positions with the use of the UCAC2 and CMC13 catalogues shows that the average external accuracy is about 0.05-0.15" for the majority ofchosenfields of the compiled catalogue. The positions of 10795 stars up to +50° in declination are given at epoch J2000.0, whereas the positions of other stars are given at the epoch of an observation.

  6. 27 CFR 70.227 - Suspension of running of period of limitation; wrongful seizure of property of third party.

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Suspension of running of... Limitations § 70.227 Suspension of running of period of limitation; wrongful seizure of property of third party. The running of the period of limitations on collection after assessment prescribed in 26...

  7. Accelerating growth of HFC-227ea (1,1,1,2,3,3,3-heptafluoropropane) in the atmosphere

    Laube, J.C.; Martinerie, P.; Witrant, E.; Brenninkmeijer, C.A.M.; Bolder, M.; Rockmann, T.; van der Veen, C; Sturges, W.T.

    2010-01-01

    We report the first measurements of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea), a substitute for ozone depleting compounds, in air samples originating from remote regions of the atmosphere and present evidence for its accelerating growth. Observed mixing ratios ranged from below 0.01 ppt in deep f

  8. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Conformity, acceptance... Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...) Conformity and acceptance. Solicitations and contracts requiring the delivery of computer software...

  9. Accelerating growth of HFC-227ea (1,1,1,2,3,3,3-heptafluoropropane) in the atmosphere

    Laube, J.C.; Martinerie, P.; Witrant, E.

    2010-01-01

    We report the first measurements of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea), a substitute for ozone depleting compounds, in air samples originating from remote regions of the atmosphere and present evidence for its accelerating growth. Observed mixing ratios ranged from below 0.01 ppt in deep...

  10. Synthesis, properties and drug potential of the photosensitive alkyl- and alkylsiloxy-ligated silicon phthalocyanine Pc 227.

    Li, Jun; Yang, Yang; Zhang, Ping; Sounik, James R; Kenney, Malcolm E

    2014-12-01

    The photosensitive, alkyl- and alkylsiloxy-ligated silicon phthalocyanine, SiPc[(CH2)3SH][OSi(CH3)2(CH2)3N(CH3)2], Pc 227, has been prepared and characterized. This phthalocyanine yields the experimental photodynamic therapy (PDT) drug Pc 4, SiPc[OH][OSi(CH3)2(CH2)3N(CH3)2], when irradiated with red light. To provide an understanding of the process by which Pc 227 and other alkyl-alkylsiloxysilicon phthalocyanines such as Pc 227 are photolyzed, bond dissociation energy, natural bond orbital (NBO) charge distribution, spin density distribution, nucleus-independent chemical shift (NICS), and electron localization function (ELF) calculations have been carried out on two models related to it. These show that the lowest energy pathway for the photolysis of Pc 227 is a homolysis involving a phthalocyanine π radical having a low SiPc-C bond dissociation energy. The promise of the results of this study for synthetic chemistry and drug development is discussed.

  11. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    2010-10-01

    ... Clauses 252.227-7018 Rights in noncommercial technical data and computer software—Small Business... the Rights in Noncommercial Technical Data and Computer Software—Small Business Innovative Research... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Rights in...

  12. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Providing computer software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer...

  13. 27 CFR 28.227 - Removals of beer by persons other than the brewer or agent of the brewer.

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Removals of beer by... ALCOHOL Exportation of Beer With Benefit of Drawback Execution of Claims § 28.227 Removals of beer by persons other than the brewer or agent of the brewer. Where there is a removal of taxpaid beer by a...

  14. Complete genome sequence of Lactobacillus plantarum LZ227, a potential probiotic strain producing B-group vitamins.

    Li, Ping; Zhou, Qingqing; Gu, Qing

    2016-09-20

    B-group vitamins play an important role in human metabolism, whose deficiencies are associated with a variety of disorders and diseases. Certain microorganisms such as Lactic acid bacteria (LAB) have been shown to have capacities for B-group vitamin production and thus could potentially replace chemically synthesized vitamins for food fortification. A potential probiotic strain named Lactobacillus plantarum LZ227, which was isolated from raw cow milk in this study, exhibits the ability to produce B-group vitamins. Complete genome sequencing of LZ227 was performed to gain insights into the genetic elements involved in B-group vitamin production. The genome of LZ227 contains a circular 3,131,750-bp chromosome, three circular plasmids and two predicted linear plasmids. LZ227 also contains gene clusters for biosynthesis of both riboflavin and folate. This genome sequence provides a basis for further elucidation of its molecular genetics and probiotic functions, and will facilitate its applications as starter cultures in food industry.

  15. Transit Timing Variation analysis with Kepler light curves of KOI 227 and Kepler 93b

    Dulz, Shannon; Reed, Mike

    2017-01-01

    By searching for transit signals in approximately 150,000 stars, NASA’s Kepler Space telescope found thousands of exoplanets over its primary mission from 2009 to 2013 (Tenenbaum et al. 2014, ApJS, 211, 6). Yet, a detailed follow-up examination of Kepler light curves may contribute more evidence on system dynamics and planetary atmospheres of these objects. Kepler’s continuous observing of these systems over the mission duration produced light curves of sufficient duration to allow for the search for transit timing variations. Transit timing variations over the course of many orbits may indicate a precessing orbit or the existence of a non-transiting third body such as another exoplanet. Flux contributions of the planet just prior to secondary eclipse may provide a measurement of bond albedo from the day-side of the transiting planet. Any asymmetries of the transit shape may indicate thermal asymmetries which can measure upper atmosphere motion of the planet. These two factors can constrain atmospheric models of close orbiting exoplanets. We first establish our procedure with the well-documented TTV system, KOI 227 (Nesvorny et al. 2014, ApJ, 790, 31). Using the test case of KOI 227, we analyze Kepler-93b for TTVs and day-side flux contributions. Kepler-93b is likely a rocky planet with R = 1.50 ± 0.03 Earth Radii and M = 2.59 ± 2.0 Earth Masses (Marcy et al. 2014, ApJS, 210, 20). This research is funded by a NASA EPSCoR grant.

  16. Renal Biopsy and Clinical Pathological Features in 227 Infants%婴幼儿227例肾穿刺及临床病理学特点

    黄丹琳; 易著文; 党西强; 吴小川; 何小解; 曹艳; 莫双红; 何庆南

    2011-01-01

    目的 分析婴幼儿肾脏疾病临床病理的特点及婴幼儿肾穿刺安全进行的方法和意义.方法 对临床诊断为肾脏疾病的227例婴幼儿进行经皮肾穿刺活检,肾脏病理组织分别进行光镜、免疫荧光和电镜观察.光镜标本做苏木精-伊红(HE)、过碘酸雪夫反应(PAS)、六胺银(PASM)和Masson染色,免疫荧光检测其肾组织中的IgG、IgM、IgA、C3、C4、C1q、Fibrin,204例标本同时行电镜检查.结果 所有患儿肾穿刺均获成功,术后无明显并发症.有肾穿刺适应证的227例婴幼儿肾脏疾病中最常见的是肾病综合征(38.3%)、孤立性血尿(37.0%)和急性肾炎综合征(9.3%),继发性肾脏疾病相对较少(5.3%).肾脏病理类型中最常见的是系膜增生性肾小球肾炎(62.6%)、IgA肾病(8.4%)和局灶节段性肾小球硬化(5.7%).87例肾病综合征病理类型最常见的是系膜增生性肾小球肾炎(50例)、微小病变(11例)和局灶节段性肾小球硬化(9例);84例孤立性血尿病理类型最常见的是系膜增生性肾小球肾炎(68例)和IgA肾病(9例).结论 在不盲目扩大适应证的基础上,安全有效地进行婴幼儿肾穿刺,可以提高婴幼儿肾脏疾病的诊治水平.%Objective To analyze the clinical and pathological features of children under 3 years with renal disease, and summarize the methods and significance of renal biopsy in infants.Methods Percutaneous renal biopsy was performed on 227 infants who were diagnosed as kidney diseases.The specimens were divided into 3 parts for light microscope, electron microscope and immunofluorescence examination respectively and processed by hematoxylin - eosin ( HE ), periodic acid - schiff( PAS ) , periodic acid - sliver methenamine ( PASM ) , and Masson staining.Immunofluorescence was used to detect the deposition of IgG, IgM, IgA, C3 , C4 , C 1q, and Fibrin in the renal tissues.Altogether 204 of the specimens were examined by electron microscope.Results All the renal

  17. Analysis of drug resistance for 227 strains enterococci%227株肠球菌细菌耐药性分析

    李怀先; 黄素荣

    2012-01-01

    Objective To study the enterococcal distribution in clinical samples and their drug resistance to commonly use antibiotic and provide the guidance for rational administration. Methods Adopting paper diffusion method to observe the drug resistance of enterococci isolated from clinical samples in our hospital and analyzing their distribution in the samples. Results En-terococcus faecalis accounts for 44. 1 % in 227 strains and Enterococcus faeciura accounts for 37. 9% , the other kinds of enterococci were rare. There was no statistical difference between drug resistance of Enterococcus faecium and that of enterococcus faecalis. Vancomycin was the most potent antimicrobial. Penicillin,ampicillin,and nitrofurantion showed good antibacterial activity against enterococcus faecalis. Enterococcus faecium displayed high-level resistance against antibiotics in addition to glycopeptides. Conclusion Doctor should pay attention to the drug resistance about clinically common pathogenic bacterium. Continual surveillance of resistance rate of enterococcus is important to direct the treatment of enterococcus infections.%目的 了解肠球菌在临床标本中的分布及对常用的抗菌药物的耐药现状,指导临床合理用药.方法 对临床标本中分离出的细菌进行系统检验,采用纸片法对分离鉴定后的肠球菌进行药物敏感性试验.结果 肠球菌可在临床常见的多种标本中检出,粪肠球菌(44.1%)与屎肠球菌(37.9%)常见,其他肠球菌(18%)少见.对常用抗菌药物的耐药性,粪肠球菌和屎肠球菌之间的差异无统计学意义.万古霉素是敏感性最高的抗生素.青霉素、氨苄西林和呋喃妥因对粪肠球菌具有较好的抗菌活性.屎肠球菌对除糖肽类抗生素以外的所有临床常用抗菌药物显示高水平耐药.结论 临床医生应关注临床常见病原菌的耐药性研究,动态监测肠球菌的耐药状况对指导临床治疗具有重要意义.

  18. Interannual variation of the quasi-two-day wave at 22.7 S

    Lima, Lourivaldo; Jacobi, Christoph; Batista, Paulo; Rodrigues de Araujo, Luciana; Rodrigues, Chayenny E. S.; Lilienthal, Friederike

    2016-07-01

    In the present investigation, the mesosphere/lower thermosphere winds at Cachoeira Paulista (22.7° S, 45.0° W) obtained by a VHF all sky interferometric meteor radar have been used to investigate the interannual variability of the quasi-two-day wave (QTDW) amplitudes at a low latitude in the Southern Hemisphere. The wind data were obtained from December 1999 to July 2006, from September 2007 to October 2008 and from December 2013 to April 2015. The analysis shows that meridional amplitudes for QTDW are larger than zonal amplitudes and the strongest amplitudes occur after austral summer solstice in January-February. Besides semiannual and annual oscillations, the QTDW amplitudes in the meridional winds also show weak quasi-biennial oscillation (QBO). The summer QTDW in the meridional winds also shows a possible correlation with solar activity. The amplitudes are nearly in phase with the 11 year solar cycle, and the solar maxima leads the QTDW maxima by one year. Finally, larger QTDW amplifications have been observed during 2003, 2004, 2006 and 2015 summers. The unusual major sudden stratospheric warming (SSW) event suggests a coupling between QTDW amplification and SSW during Jan-Feb 2006. The mechanistic global circulation model MUAM of the middle and upper atmosphere has been used to simulate the dynamic configuration during January major and minor SSW events.

  19. Study on the Relationship between Blood Stasis Syndrome and Clinical Pathology in 227 Patients with Primary Glomerular Disease

    李深; 饶向荣; 王素霞; 张改华; 李晓玫; 戴希文; 陈可冀

    2009-01-01

    To investigate the relationship between the severity of Chinese medicine(CM) bloodstasis syndrome(BSS) with clinical features and renal lesion indexes of the primary glomerular disease. Methods:An epidemiological survey was conducted to collect the data of 227 patients diagnosed as chronic primary glomerular diseases,and their severity of BSS were scored three days before renal biopsies were performed.The following clinical indexes were analyzed:age,course of glomerular diseases,24-h urine protein ration...

  20. Interaction between supernova remnant G22.7–0.2 and the ambient molecular clouds

    Su, Yang; Yang, Ji; Zhou, Xin [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Zhou, Ping; Chen, Yang [Department of Astronomy, Nanjing University, 163 Xianlin Avenue, Nanjing 210093 (China)

    2014-12-01

    We have carried out {sup 12}CO (J = 1-0 and 2-1), {sup 13}CO (J = 1-0), and C{sup 18}O (J = 1-0) observations in the direction of the supernova remnant (SNR) G22.7–0.2. A filamentary molecular gas structure, which is likely part of a larger molecular complex with V {sub LSR} ∼ 75-79 km s{sup –1}, is detected and is found to surround the southern boundary of the remnant. In particular, the high-velocity wing (77-110 km s{sup –1}) in the {sup 12}CO (J = 1-0 and J = 2-1) emission shows convincing evidence of the interaction between SNR G22.7–0.2 and the 75-79 km s{sup –1} molecular clouds (MCs). Spectra with redshifted profiles, a signature of shocked molecular gas, are seen in the southeastern boundary of the remnant. The association between the remnant and the 77 km s{sup –1} MCs places the remnant at the near distance of 4.4 ± 0.4 kpc, which agrees with a location on the Scutum-Crux arm. We suggest that SNR G22.7–0.2, SNR W41, and H II region G022.760-0.485 are at the same distance and are associated with GMC G23.0–0.4.

  1. Outcomes From AAS Hack Day at the 227th AAS Meeting

    Kohler, Susanna

    2016-01-01

    Editors Note:This is a final post from the 227th AAS Meeting in Kissimmee, FL. This special summary of AAS Hack Day, a meeting of AAS members to collaboratively work on various small projects, was written by Meredith Rawls (@Merrdiff) and was originally posted on astrobites.com.As the 227thAmerican Astronomical Society meeting drew to a close (see highlights from Day 1, Day 2, Day 3, and Day 4), a group of at least 50 attendees spent Day 4working on small projects fondly called hacks. Thanks to sponsorship from LSST and Northrup Grumman, the industrious hackers werewell-caffeinated and fed so we could devote time and energy toworking in groups on one-day projects.TheHack Day beganat 10am with pitches. Anybody with a project idea was welcome to briefly speak and try to convince others to work with them. Only someideas panned out, but the enthusiasm was palpable. Its not every day you get a full room of astronomers and affiliates eager to spend hours working on fun and useful projects to benefit the community.#hackAAS is getting underway! #aas227 pic.twitter.com/yX7jlOnSCK James R A Davenport (@jradavenport) January 8, 2016Here is a rundown of what we accomplished. Pretty impressive for a single day! Many thanks to fellow astrobiter Erika Nesvold (now at Carnegie DTM; @erikanesvold) whose hack was live-documenting all the other hacks. Her tweets as @astrobites appeared with the #hackaas hashtag, and her notes made this recap post infinitely easier to write.Interested in joining the fun? Sign up for Hack Day at the 2017 JanuaryAAS meeting (its free with meeting registration), and consider applying for the .Astronomy conference this summer.Towards Optimal Session Scheduling:Adrian Price-Whelan (Columbia), David Hogg (NYU), and Scott Idem (AAS) began writing a program to take all submitted abstracts to a conference like AAS and sort them using keywords to avoid scheduling similar talks in parallel sessions. Its impossible to make everyone happy, but minimizing conflicts

  2. Combined renin inhibition/(prorenin receptor blockade in diabetic retinopathy--a study in transgenic (mREN227 rats.

    Wendy W Batenburg

    Full Text Available Dysfunction of renin-angiotensin system (RAS contributes to the pathogenesis of diabetic retinopathy (DR. Prorenin, the precursor of renin is highly elevated in ocular fluid of diabetic patients with proliferative retinopathy. Prorenin may exert local effects in the eye by binding to the so-called (prorenin receptor ((PRR. Here we investigated the combined effects of the renin inhibitor aliskiren and the putative (PRR blocker handle-region peptide (HRP on diabetic retinopathy in streptozotocin (STZ-induced diabetic transgenic (mRen227 rats (a model with high plasma prorenin levels as well as prorenin stimulated cytokine expression in cultured Müller cells. Adult (mRen227 rats were randomly divided into the following groups: (1 non-diabetic; (2 diabetic treated with vehicle; (3 diabetic treated with aliskiren (10 mg/kg per day; and (4 diabetic treated with aliskiren+HRP (1 mg/kg per day. Age-matched non-diabetic wildtype Sprague-Dawley rats were used as control. Drugs were administered by osmotic minipumps for three weeks. Transgenic (mRen227 rat retinas showed increased apoptotic cell death of both inner retinal neurons and photoreceptors, increased loss of capillaries, as well as increased expression of inflammatory cytokines. These pathological changes were further exacerbated by diabetes. Aliskiren treatment of diabetic (mRen227 rats prevented retinal gliosis, and reduced retinal apoptotic cell death, acellular capillaries and the expression of inflammatory cytokines. HRP on top of aliskiren did not provide additional protection. In cultured Müller cells, prorenin significantly increased the expression levels of IL-1α and TNF-α, and this was completely blocked by aliskiren or HRP, their combination, (PRR siRNA and the AT1R blocker losartan, suggesting that these effects entirely depended on Ang II generation by (PRR-bound prorenin. In conclusion, the lack of effect of HRP on top of aliskiren, and the Ang II-dependency of the ocular

  3. Standardized, systemic phenotypic analysis of Umod(C93F and Umod(A227T mutant mice.

    Elisabeth Kemter

    Full Text Available Uromodulin-associated kidney disease (UAKD summarizes different clinical features of an autosomal dominant heritable disease syndrome in humans with a proven uromodulin (UMOD mutation involved. It is often characterized by hyperuricemia, gout, alteration of urine concentrating ability, as well as a variable rate of disease progression inconstantly leading to renal failure and histological alterations of the kidneys. We recently established the two Umod mutant mouse lines Umod(C93F and Umod(A227T on the C3H inbred genetic background both showing kidney defects analogous to those found in human UAKD patients. In addition, disease symptoms were revealed that were not yet described in other published mouse models of UAKD. To examine if further organ systems and/or metabolic pathways are affected by Umod mutations as primary or secondary effects, we describe a standardized, systemic phenotypic analysis of the two mutant mouse lines Umod(A227T and Umod(C93F in the German Mouse Clinic. Different genotypes as well as different ages were tested. Beside the already published changes in body weight, body composition and bone metabolism, the influence of the Umod mutation on energy metabolism was confirmed. Hematological analysis revealed a moderate microcytic and erythropenic anemia in older Umod mutant mice. Data of the other analyses in 7-10 month-old mutant mice showed single small additional effects.

  4. Effects of carbon and nitrogen sources on fatty acid contents and composition in the green microalga, Chlorella sp. 227.

    Cho, Sunja; Lee, Dukhaeng; Luong, Thao Thanh; Park, Sora; Oh, You-Kwan; Lee, Taeho

    2011-10-01

    In order to investigate and generalize the effects of carbon and nitrogen sources on the growth of and lipid production in Chlorella sp. 227, several nutritional combinations consisting of different carbon and nitrogen sources and concentrations were given to the media for cultivation of Chlorella sp. 227, respectively. The growth rate and lipid content were affected largely by concentration rather than by sources. The maximum specific growth was negatively affected by low concentrations of carbon and nitrogen. There is a maximum allowable inorganic carbon concentration (less than 500~1,000 mM bicarbonate) in autotrophic culture, but the maximum lipid content per gram dry cell weight (g DCW) was little affected by the concentration of inorganic carbon within the concentration. The lipid content per g DCW was increased when the microalga was cultured with the addition of glucose and bicarbonate (mixotrophic) at a fixed nitrogen concentration and with the lowest nitrogen concentration (0.2 mM), relatively. Considering that lipid contents per g DCW increased in those conditions, it suggests that a high ratio of carbon to nitrogen in culture media promotes lipid accumulation in the cells. Interestingly, a significant increase of the oleic acid amount to total fatty acids was observed in those conditions. These results showed the possibility to induce lipid production of high quality and content per g DCW by modifying the cultivation conditions.

  5. Assessment of long-term radiotoxicity after treatment with the low-dose-rate alpha-particle-emitting radioimmunoconjugate {sup 227}Th-rituximab

    Dahle, Jostein; Heyerdahl, Helen; Hjelmerud, Anne Kristine; Larsen, Roy H. [Oslo University Hospital, Department of Radiation Biology, The Norwegian Radium Hospital, Oslo (Norway); Jonasdottir, Thora J. [Norwegian School of Veterinary Science, Small Animal Section, Department of Companion Animal Clinical Sciences, Oslo (Norway); Nesland, Jahn M. [Oslo University Hospital, Division of Pathology, The Norwegian Radium Hospital, Oslo (Norway); University of Oslo, Faculty Division The Norwegian Radium Hospital, Medical Faculty, Oslo (Norway); Borrebaek, Joergen [Algeta AS, Oslo (Norway)

    2010-01-15

    The anti-CD20 antibody rituximab labelled with the {alpha}-particle-emitting radionuclide {sup 227}Th is of interest as a radiotherapeutic agent for treatment of lymphoma. Complete regression of human lymphoma Raji xenografts in 60% of mice treated with 200 kBq/kg {sup 227}Th-rituximab has been observed. To evaluate possible late side effects of {sup 227}Th-rituximab, the long-term radiotoxicity of this potential radiopharmaceutical was investigated. BALB/c mice were injected with saline, cold rituximab or 50, 200 or 1,000 kBq/kg {sup 227}Th-rituximab and followed for up to 1 year. In addition, nude mice with Raji xenografts treated with various doses of {sup 227}Th-rituximab were also included in the study. Toxicity was evaluated by measurements of mouse body weight, white blood cell (WBC) and platelet counts, serum clinical chemistry parameters and histological examination of tissues. Only the 1,000 kBq/kg dosage resulted in decreased body weight of the BALB/c mice. There was a significant but temporary decrease in WBC and platelet count in mice treated with 400 and 1,000 kBq/kg {sup 227}Th-rituximab. Therefore, the no-observed-adverse-effect level (NOAEL) was 200 kBq/kg. The maximum tolerated activity was between 600 and 1,000 kBq/kg. No significant signs of toxicity were observed in histological sections in any examined tissue. There were significantly (p < 0.05), but transiently, higher concentrations of serum bile acids and aspartate aminotransferase in mice treated with either {sup 227}Th-rituximab or non-labelled antibody when compared with control mice. The maximum tolerated dose to bone marrow was between 2.1 and 3.5 Gy. Therapeutically relevant dose levels of {sup 227}Th-rituximab were well tolerated in mice. Bone marrow suppression, as indicated by decrease in WBC count, was the dose-limiting radiotoxicity. These toxicity data together with anti-tumour activity data in a CD20-positive xenograft mouse model indicate that therapeutic effects could be

  6. A synchrotron study of Na2.27Ho7.73(SiO46O0.72

    Luis Fuentes

    2009-05-01

    Full Text Available A well crystallized powder sample of sodium holmium orthosilicate oxyapatite, Na2.27Ho7.73(SiO46O0.72, was obtained after mechanical milling and thermal treatment at 1123 K. Crystal structure analysis was performed from the results of Rietveld refinement of the synchrotron diffraction data. As in other rare-earth orthosilicate apatites, sodium cations appear located sharing with holmium the 4f Wyckoff position at the center of a tricapped trigonal prism. In its turn, holmium almost fully occupies the 6h position at the center of a seven-coordinated pentagonal bipyramid. A small quantity of Na atoms was found at this site. No vacancies are present in the two independent crystallographic sites available for Ho and Na atoms.

  7. Dissociation of blood pressure reduction from end-organ damage in TGR(mREN2)27 transgenic hypertensive rats

    Teisman, ACH; Pinto, YM; Buikema, H; Flesch, M; Bohm, M; Paul, M; van Gilst, WH

    1998-01-01

    Objective Since the biochemical disturbance underlying hypertension may be an important determinant of patient outcome, we compared the effects of early treatment with different antihypertensive drugs on end-organ damage in the TGR(mREN2)27 transgenic rat (REN-P), In these REN-P rats, hypertension i

  8. Structural insights into parasite eIF4E binding specificity for m7G and m2,2,7G mRNA caps.

    Liu, Weizhi; Zhao, Rui; McFarland, Craig; Kieft, Jeffrey; Niedzwiecka, Anna; Jankowska-Anyszka, Marzena; Stepinski, Janusz; Darzynkiewicz, Edward; Jones, David N M; Davis, Richard E

    2009-11-06

    The eukaryotic translation initiation factor eIF4E recognizes the mRNA cap, a key step in translation initiation. Here we have characterized eIF4E from the human parasite Schistosoma mansoni. Schistosome mRNAs have either the typical monomethylguanosine (m(7)G) or a trimethylguanosine (m(2,2,7)G) cap derived from spliced leader trans-splicing. Quantitative fluorescence titration analyses demonstrated that schistosome eIF4E has similar binding specificity for both caps. We present the first crystal structure of an eIF4E with similar binding specificity for m(7)G and m(2,2,7)G caps. The eIF4E.m(7)GpppG structure demonstrates that the schistosome protein binds monomethyl cap in a manner similar to that of single specificity eIF4Es and exhibits a structure similar to other known eIF4Es. The structure suggests an alternate orientation of a conserved, key Glu-90 in the cap-binding pocket that may contribute to dual binding specificity and a position for mRNA bound to eIF4E consistent with biochemical data. Comparison of NMR chemical shift perturbations in schistosome eIF4E on binding m(7)GpppG and m(2,2,7)GpppG identified key differences between the two complexes. Isothermal titration calorimetry demonstrated significant thermodynamics differences for the binding process with the two caps (m(7)G versus m(2,2,7)G). Overall the NMR and isothermal titration calorimetry data suggest the importance of intrinsic conformational flexibility in the schistosome eIF4E that enables binding to m(2,2,7)G cap.

  9. Modifications in Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameters After α-Particle-Emitting {sup 227}Th-trastuzumab Therapy of HER2-Expressing Ovarian Cancer Xenografts

    Heyerdahl, Helen, E-mail: Helen.Heyerdahl@rr-research.no [Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital - The Norwegian Radium Hospital, Oslo (Norway); Røe, Kathrine [Department of Oncology, Division of Medicine, Akershus University Hospital, Lørenskog (Norway); Brevik, Ellen Mengshoel [Department of Research and Development, Algeta ASA, Oslo (Norway); Dahle, Jostein [Nordic Nanovector AS, Oslo (Norway)

    2013-09-01

    Purpose: The purpose of this study was to investigate the effect of α-particle-emitting {sup 227}Th-trastuzumab radioimmunotherapy on tumor vasculature to increase the knowledge about the mechanisms of action of {sup 227}Th-trastuzumab. Methods and Materials: Human HER2-expressing SKOV-3 ovarian cancer xenografts were grown bilaterally in athymic nude mice. Mice with tumor volumes 253 ± 36 mm{sup 3} (mean ± SEM) were treated with a single injection of either {sup 227}Th-trastuzumab at a dose of 1000 kBq/kg body weight (treated group, n=14 tumors) or 0.9% NaCl (control group, n=10 tumors). Dynamic T1-weighted contrast-enhanced magnetic resonance imaging (DCEMRI) was used to study the effect of {sup 227}Th-trastuzumab on tumor vasculature. DCEMRI was performed before treatment and 1, 2, and 3 weeks after therapy. Tumor contrast-enhancement curves were extracted voxel by voxel and fitted to the Brix pharmacokinetic model. Pharmacokinetic parameters for the tumors that underwent radioimmunotherapy were compared with the corresponding parameters of control tumors. Results: Significant increases of k{sub ep}, the rate constant of diffusion from the extravascular extracellular space to the plasma (P<.05), and k{sub el,} the rate of clearance of contrast agent from the plasma (P<.01), were seen in the radioimmunotherapy group 2 and 3 weeks after injection, compared with the control group. The product of k{sub ep} and the amplitude parameter A, associated with increased vessel permeability and perfusion, was also significantly increased in the radioimmunotherapy group 2 and 3 weeks after injection (P<.01). Conclusions: Pharmacokinetic modeling of MRI contrast-enhancement curves evidenced significant alterations in parameters associated with increased tumor vessel permeability and tumor perfusion after {sup 227}Th-trastuzumab treatment of HER2-expressing ovarian cancer xenografts.

  10. 10 CFR Appendix E to Part 20 - Nationally Tracked Source Thresholds

    2010-01-01

    ... Category 1(TBq) Category 1(Ci) Category 2(TBq) Category 2(Ci) Actinium-227 20 540 0.2 5.4 Americium-241 60... 2 54 Strontium-90 1,000 27,000 10 270 Thorium-228 20 540 0.2 5.4 Thorium-229 20 540 0.2 5.4...

  11. Restricted diversity of antigen binding residues of antibodies revealed by computational alanine scanning of 227 antibody-antigen complexes.

    Robin, Gautier; Sato, Yoshiteru; Desplancq, Dominique; Rochel, Natacha; Weiss, Etienne; Martineau, Pierre

    2014-11-11

    Antibody molecules are able to recognize any antigen with high affinity and specificity. To get insight into the molecular diversity at the source of this functional diversity, we compiled and analyzed a non-redundant aligned collection of 227 structures of antibody-antigen complexes. Free energy of binding of all the residue side chains was quantified by computational alanine scanning, allowing the first large-scale quantitative description of antibody paratopes. This demonstrated that as few as 8 residues among 30 key positions are sufficient to explain 80% of the binding free energy in most complexes. At these positions, the residue distribution is not only different from that of other surface residues but also dependent on the role played by the side chain in the interaction, residues participating in the binding energy being mainly aromatic residues, and Gly or Ser otherwise. To question the generality of these binding characteristics, we isolated an antibody fragment by phage display using a biased synthetic repertoire with only two diversified complementarity-determining regions and solved its structure in complex with its antigen. Despite this restricted diversity, the structure demonstrated that all complementarity-determining regions were involved in the interaction with the antigen and that the rules derived from the natural antibody repertoire apply to this synthetic binder, thus demonstrating the robustness and universality of our results.

  12. MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells.

    Mukherjee, P; Tinder, T L; Basu, G D; Gendler, S J

    2005-01-01

    MUC1 (CD227) is a large transmembrane epithelial mucin glycoprotein, which is aberrantly overexpressed in most adenocarcinomas and is a target for immune therapy for epithelial tumors. Recently, MUC1 has been detected in a variety of hematopoietic cell malignancies including T and B cell lymphomas and myelomas; however, its function in these cells is not clearly defined. Using the Jurkat T cell lymphoma cell line and normal human T cells, we demonstrate that MUC1 is not only expressed in these cells but is also phosphorylated upon T cell receptor (TCR) ligation and associates with the Src-related T cell tyrosine kinase, p56lck. Upon TCR-mediated activation of Jurkat cells, MUC1 is found in the low-density membrane fractions, where linker of T cell activation is contained. Abrogation of MUC1 expression in Jurkat cells by MUC1-specific small interfering RNA resulted in defects in TCR-mediated downstream signaling events associated with T cell activation. These include reduction in Ca2+ influx and extracellular signal-regulated kinase 1/2 phosphorylation, leading to a decrease in CD69 expression, proliferation, and interleukin-2 production. These results suggest a regulatory role of MUC1 in modulating proximal signal transduction events through its interaction with proteins of the activation complex.

  13. Biosynthesis of high yield fatty acids from Chlorella vulgaris NIES-227 under nitrogen starvation stress during heterotrophic cultivation.

    Shen, Xiao-Fei; Chu, Fei-Fei; Lam, Paul K S; Zeng, Raymond J

    2015-09-15

    In this study the heterotrophic cultivation of Chlorella vulgaris NIES-227 fed with glucose was investigated systematically using six media types; combinations of nitrogen repletion/depletion and phosphorus repletion/limitation/depletion. It was found that a high yield of fatty acids (0.88 of fed glucose-COD) and a high content of fatty acid methyl esters (FAMEs) (89% of dry weight) were obtained under nitrogen starved conditions. To our knowledge it is the first report on such high COD conversion yield and FAME content in microalgae. The dominant fatty acid (>50%) was methyl oleate (C18:1), a desirable component for biodiesel synthesis. FAME content under nitrogen starved conditions was significantly higher than under nitrogen sufficient conditions, while phosphorus had no significant influence, indicating that nitrogen starvation was the real "fatty acids trigger" in heterotrophic cultivation. These findings could simplify the downstream extraction process, such as the extrusion of oil from soybeans, and could reduce operating costs by improving the fatty acid yield from waste COD.

  14. Isolation of Actinium from Neutron-irradiated Thorium-I

    1994-01-01

    Isolation of Actinium from Neutron-irradiated Thorium-I¥YangWeifan;YuanShuanggui;MuWantong;ZhangXueqian;LiZhongweiandZhaoLili...

  15. Production of actinium-225 for alpha particle mediated radioimmunotherapy.

    Boll, Rose A; Malkemus, Dairin; Mirzadeh, Saed

    2005-05-01

    The initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the alpha emitter (213)Bi in killing cancer cells. Bismuth-213 is obtained from a radionuclide generator system from decay of 10-days (225)Ac parent. Recent pre-clinical studies have also shown the potential application of both (213)Bi, and the (225)Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy. This paper describes our five years of experience in production of (225)Ac in partial support of the on-going clinical trials. A four-step chemical process, consisting of both anion and cation exchange chromatography, is utilized for routine separation of carrier-free (225)Ac from a mixture of (228)Th, (229)Th and (232)Th. The separation of Ra and Ac from Th is achieved using the marcoporous anion exchange resin MP1 in 8M HNO(3) media. Two sequential MP1/NO(3) columns provide a separation factor of approximately 10(6) for Ra and Ac from Th. The separation of Ac from Ra is accomplished on a low cross-linking cation exchange resin AG50-X4 using 1.2M HNO(3) as eluant. Two sequential AG50/NO(3) columns provide a separation factor of approximately 10(2) for Ac from Ra. A 60-day processing schedule has been adopted in order to reduce the processing cost and to provide the highest levels of (225)Ac possible. Over an 8-week campaign, a total of approximately 100 mCi of (225)Ac (approximately 80% of the theoretical yield) is shipped in 5-6 batches, with the first batch typically consisting of approximately 50 mCi. After the initial separation and purification of Ac, the Ra pool is re-processed on a bi-weekly schedule or as needed to provide smaller batches of (225)Ac. The averaged radioisotopic purity of the (225)Ac was 99.6 +/- 0.7% with a (225)Ra content of < or =0.6%, and an average (229)Th content of (4(-4)(+5)) x 10(-5)%.

  16. An unusual patient with hypercalciuria, recurrent nephrolithiasis, hypomagnesemia and G227R mutation of Paracellin-1. An unusual patient with hypercalciuria and hypomagnesemia unresponsive to thiazide diuretics.

    Kutluturk, Faruk; Temel, Berna; Uslu, Bora; Aral, Ferihan; Azezli, Adil; Orhan, Yusuf; Konrad, Martin; Ozbey, Nese

    2006-01-01

    A 19-year-old female patient with hypercalciuria and recurrent nephrolithiasis/urinary tract infection unresponsive to thiazide type diuretics is presented. The patient first experienced nephrolithiasis at the age of 4 years. Afterwards, recurrent passages of stones and urinary tract infection occurred. On diagnostic evaluation at the age of 19 years, she also had hypocitraturia and hypomagnesemia. Her serum calcium concentrations were near the lower limit of normal (8.5-8.8 mg/dl; normal range: 8.5-10.5), her serum magnesium concentrations were 1.15-1.24 mg/dl (normal range: 1.4-2.5) and urinary calcium excretion was 900 mg/24 h. PTH concentrations were increased (110-156 pg/ml; normal range: 10-65). We tried to treat the patient with hydrochlorothiazide at a dose of 50 mg/day. During treatment with thiazide diuretics, PTH concentration remained high and the patient had recurrent urinary tract infections and passages of stones. Serum magnesium concentration did not normalize even under the parenteral magnesium infusion. Her mother had a history of nephrolithiasis 20 years ago. Severe hypomagnesemia in association with hypercalciuria/urinary stones is reported as a rare autosomal recessive disorder caused by impaired reabsorption of magnesium and calcium in the thick assending limp of Henle's loop. Recent studies showed that mutations in the CLDN16 gene encoding paracellin-1 cause the disorder. In exon 4, a homozygous nucleotide exchange (G679C) was identified for the patient. This results in a point mutation at position Glycine227, which is replaced by an Arginine residue (G227R). The mother was heterozygous for this mutation. G227 is located in the fourth transmembrane domain and is highly conserved in the claudin gene family. This case indicates the pathogenetic role of paracellin-1 mutation in familial hypomagnesemia with hypercalciuria and nephrocalcinosis and further underlines the risk of stone formation in heterozygous mutation carriers.

  17. In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats.

    Garcia-Espinosa, Maria A; Shaltout, Hossam A; Gallagher, Patricia E; Chappell, Mark C; Diz, Debra I

    2012-08-01

    Transgenic (mRen2)27 rats are hypertensive with impaired baroreflex sensitivity for control of heart rate compared with Hannover Sprague-Dawley rats. We assessed blood pressure and baroreflex function in male hemizygous (mRen2)27 rats (30-40 weeks of age) instrumented for arterial pressure recordings and receiving into the cisterna magna either an Ang-(1-7) fusion protein or a control fusion protein (CTL-FP). The maximum reduction in mean arterial pressure achieved was -38 ± 7 mm Hg on day 3, accompanied by a 55% enhancement in baroreflex sensitivity in Ang-(1-7) fusion protein-treated rats. Both the high-frequency alpha index (HF-α) and heart rate variability increased, suggesting increased parasympathetic tone for cardiac control. The mRNA levels of several components of the renin-angiotensin system in the dorsal medulla were markedly reduced including renin (-80%), neprilysin (-40%), and the AT1a receptor (-40%). However, there was a 2-fold to 3-fold increase in the mRNA levels of the phosphatases PTP-1b and dual-specificity phosphatase 1 in the medulla of Ang-(1-7) fusion protein-treated rats. Our finding that replacement of Ang-(1-7) in the brain of (mRen2)27 rats reverses in part the hypertension and baroreflex impairment is consistent with a functional deficit of Ang-(1-7) in this hypertensive strain. We conclude that the increased mRNA expression of phosphatases known to counteract the phosphoinositol 3 kinase and mitogen-activated protein kinases, and the reduction of renin and AT1a receptor mRNA levels may contribute to the reduction in arterial pressure and improvement in baroreflex sensitivity in response to Ang-(1-7).

  18. Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats.

    Schaich, Chris L; Shaltout, Hossam A; Brosnihan, K Bridget; Howlett, Allyn C; Diz, Debra I

    2014-08-01

    We investigated acute and chronic effects of CB1 cannabinoid receptor blockade in renin-angiotensin system-dependent hypertension using rimonabant (SR141716A), an orally active antagonist with central and peripheral actions. In transgenic (mRen2)27 rats, a model of angiotensin II-dependent hypertension with increased body mass and insulin resistance, acute systemic blockade of CB1 receptors significantly reduced blood pressure within 90 min but had no effect in Sprague-Dawley rats. No changes in metabolic hormones occurred with the acute treatment. During chronic CB1 receptor blockade, (mRen2)27 rats received daily oral administration of SR141716A (10 mg/kg/day) for 28 days. Systolic blood pressure was significantly reduced within 24 h, and at Day 21 of treatment values were 173 mmHg in vehicle versus 149 mmHg in drug-treated rats (P < 0.01). This accompanied lower cumulative weight gain (22 vs. 42 g vehicle; P < 0.001), fat mass (2.0 vs. 2.9% of body weight; P < 0.05), and serum leptin (2.8 vs. 6.0 ng/mL; P < 0.05) and insulin (1.0 vs. 1.9 ng/mL; P < 0.01), following an initial transient decrease in food consumption. Conscious hemodynamic recordings indicate twofold increases occurred in spontaneous baroreflex sensitivity (P < 0.05) and heart rate variability (P < 0.01), measures of cardiac vagal tone. The beneficial actions of CB1 receptor blockade in (mRen2)27 rats support the interpretation that an upregulated endocannabinoid system contributes to hypertension and impaired autonomic function in this angiotensin II-dependent model. We conclude that systemic CB1 receptor blockade may be an effective therapy for angiotensin II-dependent hypertension and associated metabolic syndrome.

  19. Planetary wave seasonality from meteor wind measurements at 7.4° S and 22.7° S

    Araújo, L. R.; Lima, L. M.; Batista, P. P.; Clemesha, B. R.; Takahashi, H.

    2014-05-01

    In this study we have used wind observation data from the mesosphere and lower thermosphere (MLT) region, obtained from meteor radar measurements in São João do Cariri (7.4° S, 36.5° W) from July 2004 to December 2008 and in Cachoeira Paulista (22.7° S, 45.0° W) from January 2002 to July 2006 and from September 2007 to November 2008. From the spectral analysis it was possible to identify the presence of planetary-scale oscillations in the hourly winds for the two latitudes and to study their transient character, which allowed elaboration of a climatology of planetary oscillation signatures. Planetary waves with periods near 2-days, 6-7 days, and 16 days were focussed on in this study. The quasi-2-day waves in the meteoric winds showed a seasonal cycle, with intense amplitudes occurring after the austral summer solstice and extending until the end of the season. The vertical wavelengths of the 2-day wave over Cachoeira Paulista were larger than those at São João do Cariri. A possible modulation of the quasi-2-day wave amplitudes by the quasi-biennial oscillation (QBO) has been observed only at São João do Cariri. The 6-7 day oscillations presented more intense amplitudes during August-November but were present with lower amplitudes during March-April at both sites. The 6-7 day vertical wavelengths over São João do Cariri were larger than at Cachoeira Paulista. The 6-7 day amplitudes exhibited intra-seasonal and annual behavior, however, there was no clear evidence of QBO modulation. The 16-day oscillations showed a seasonal cycle at São João do Cariri, with amplifications from austral spring to mid-summer and weaker amplitudes from autumn until early winter, however, there was no clear seasonality over Cachoeira Paulista. The 16-day vertical wavelengths have assumed values of λz ~ 45-85 km over both sites. 16-day wave amplitudes at the two sites showed different long-term behaviors.

  20. Combined renin inhibition/(pro)renin receptor blockade in diabetic retinopathy--a study in transgenic (mREN2)27 rats.

    Batenburg, Wendy W; Verma, Amrisha; Wang, Yunyang; Zhu, Ping; van den Heuvel, Mieke; van Veghel, Richard; Danser, A H Jan; Li, Qiuhong

    2014-01-01

    Dysfunction of renin-angiotensin system (RAS) contributes to the pathogenesis of diabetic retinopathy (DR). Prorenin, the precursor of renin is highly elevated in ocular fluid of diabetic patients with proliferative retinopathy. Prorenin may exert local effects in the eye by binding to the so-called (pro)renin receptor ((P)RR). Here we investigated the combined effects of the renin inhibitor aliskiren and the putative (P)RR blocker handle-region peptide (HRP) on diabetic retinopathy in streptozotocin (STZ)-induced diabetic transgenic (mRen2)27 rats (a model with high plasma prorenin levels) as well as prorenin stimulated cytokine expression in cultured Müller cells. Adult (mRen2)27 rats were randomly divided into the following groups: (1) non-diabetic; (2) diabetic treated with vehicle; (3) diabetic treated with aliskiren (10 mg/kg per day); and (4) diabetic treated with aliskiren+HRP (1 mg/kg per day). Age-matched non-diabetic wildtype Sprague-Dawley rats were used as control. Drugs were administered by osmotic minipumps for three weeks. Transgenic (mRen2)27 rat retinas showed increased apoptotic cell death of both inner retinal neurons and photoreceptors, increased loss of capillaries, as well as increased expression of inflammatory cytokines. These pathological changes were further exacerbated by diabetes. Aliskiren treatment of diabetic (mRen2)27 rats prevented retinal gliosis, and reduced retinal apoptotic cell death, acellular capillaries and the expression of inflammatory cytokines. HRP on top of aliskiren did not provide additional protection. In cultured Müller cells, prorenin significantly increased the expression levels of IL-1α and TNF-α, and this was completely blocked by aliskiren or HRP, their combination, (P)RR siRNA and the AT1R blocker losartan, suggesting that these effects entirely depended on Ang II generation by (P)RR-bound prorenin. In conclusion, the lack of effect of HRP on top of aliskiren, and the Ang II-dependency of the ocular

  1. Origem e avaliação de trigo 'Tapajós' (IAC 72, 'Anhumas' (IAC 227 e 'Yaco' (IAC 287 para o estado de São Paulo Evaluation of the agronomic and technologic characteristics of the wheat cultivars: IAC 72 Tapajós, IAC 227 Anhumas and IAC 287 Yaco in the State of São Paulo, Brazil

    João Carlos Felício

    1994-01-01

    Full Text Available Estudou-se o comportamento de trigo 'Tapajós' (IAC 72, 'Anhumas' (IAC 227 e 'Yaco' (IAC 287 quanto à produtividade, às reações aos agentes causais das ferrugens-do-colmo e da-folha (em condição de campo e de casa de vegetação e à helmintosporiose, em experimentos instalados em solos corrigidos e não corrigidos em relação à acidez, em condição de sequeiro e de irrigação por aspersão, em diferentes regiões paulistas, no período de 1987-91. Os cultivares foram submetidos a testes para avaliação de tolerância a ferro, alumínio e manganês, empregando-se soluções nutritivas, em laboratório. Avaliaram-se também as qualidades físicas e reológicas das farinhas obtidas dos grãos desses cultivares e efetuou-se o teste final de panificação. Nas condições de sequeiro, os cultivares IAC 227 e IAC 72 foram mais produtivos em 20 e 5%, respectivamente, em relação ao BH 1146, tomado como controle. O IAC 287, nas mesmas condições de cultivo, apresentou uma produção de grãos 10% maior em relação à testemunha, Anahuac, e em condição de irrigação foi superior em 7 e 6% aos controles Anahuac e IAC 24 respectivamente. Para a ferrugem-do-colmo, em casa de vegetação, o IAC 72 demonstrou suscetibilidade às raças G20 e G21; o IAC 227, às raças G11, G15 e G17; o BH 1146 mostrou-se sensível e os cultivares IAC 287 e Anahuac, resistentes a todas as raças testadas. Os testes para reação a Puccinia recondita, em casa de vegetação, demonstraram suscetibilidade dos cultivares IAC 72, IAC 227, BH 1146 e Anahuac, enquanto o IAC 287 mostrou-se resistente. Esses resultados foram confirmados nos testes de campo. Todos os cultivares em estudo apresentaram-se sensíveis à ocorrência do agente causal da helmintosporiose. O IAC 72 revelou moderada suscetibilidade ao A1(3+ e Mn2+ e sensibilidade ao Fe2+; o IAC 227 foi tolerante a altas doses de A1(3+ e a Mn2+ e sensível ao Fe2+; o IAC 287, tolerante ao Fe2+ e Mn2+ e sens

  2. Development of separation technology for the removal of radium-223 from decayed thorium-227 in drug formulations. Material screening and method development.

    Frenvik, Janne Olsen; Kristensen, Solveig; Ryan, Olav B

    2016-08-01

    Targeted thorium conjugates are currently being investigated as a new class of alpha-radiopharmaceuticals. The natural decay of thorium-227 ((227)Th) results in the ingrowth of radium-223 ((223)Ra). Consideration must, therefore, be given to define acceptable limits of (223)Ra in the drug product at the time of dose administration. By effective sequestration of (223)Ra, we aim to improve the radiochemical purity and extend the effective user window of drug products containing (227)Th. (223)Ra is the first progeny of (227)Th and the only one with a long half-life (days). We have, therefore, focused on the removal of this specific species since the progenies of (223)Ra will have a very limited lifetime in the formulation once (223)Ra is removed. In this study, we investigated a multitude of materials for their ability to reduce the (223)Ra level by: (1) passive diffusion or (2) by cartridge filtration on gravity columns. In addition, we probe the compatibility of these materials in the presence of antibody trastuzumab to assess the level of protein binding and estimate the quenching of radiolysis by binding of radionuclides. A screening matrix of organic and inorganic materials was established, i.e. strontium and calcium alginate gel beads, distearoyl phosphatidylglycerol (DSPG) liposomes, ceramic hydroxyapatite, Zeolite UOP type 4A and cation exchange resins AG50W-X8 and SOURCE 30S. First, passive diffusional uptake of (223)Ra by suspended materials present in the formulation was measured as a decrease in sample radioactivity after separation. Second, selected materials were packed on gravity columns in order to evaluate the efficiency of column separation versus diffusional adsorption. The retention of (223)Ra and (227)Th were characterized by measuring the radioactivity in the eluate and on the columns. Finally, the compatibility between trastuzumab, as a selected model antibody, and suspensions of the binding materials was analyzed during storage of the drug

  3. Central angiotensin-(1-7) improves vagal function independent of blood pressure in hypertensive (mRen2)27 rats.

    Nautiyal, Manisha; Shaltout, Hossam A; de Lima, Daniel C; do Nascimento, Kenia; Chappell, Mark C; Diz, Debra I

    2012-11-01

    Hypertensive transgenic (mRen2)27 rats with overexpression of the mRen2 gene have impaired baroreflex sensitivity for heart rate control and high nicotinamide adenine dinucleotide phosphate oxidase and kinase-to-phosphatase signaling activity in medullary tissue compared with normotensive Hannover Sprague-Dawley control rats. They also exhibit insulin resistance at a young age. To determine whether blocking angiotensin II actions, supplementing angiotensin-(1-7), or scavenging reactive oxygen species in brain differentially alters mean arterial pressure, baroreflex sensitivity, or metabolic function, while altering medullary signaling pathways in these animals, we compared intracerebroventricular infusions of the angiotensin II type 1 receptor antagonist candesartan (4 μg/5 μL/h), angiotensin-(1-7) (0.1 μg/5 μL/h), a reactive oxygen species scavenger tempol (25 μg/5 μL/h), or artificial cerebrospinal fluid (5 μL/h) for 2 weeks. Mean arterial pressure was reduced in candesartan-treated rats without significantly improving the vagal components of baroreflex function or heart rate variability. In contrast, angiotensin-(1-7) treatment significantly improved the vagal components of baroreflex function and heart rate variability at a dose that did not significantly lower mean arterial pressure. Tempol significantly reduced nicotinamide adenine dinucleotide phosphate oxidase activity in brain dorsal medullary tissue but had no effect on mean arterial pressure or autonomic function. Candesartan tended to reduce fat mass, but none of the treatments significantly altered indices of metabolic function or mitogen-activated protein kinase signaling pathways in dorsal medulla. Although additional dose response studies are necessary to determine the potential maximal effectiveness of each treatment, the current findings demonstrate that blood pressure and baroreflex function can be essentially normalized independently of medullary nicotinamide adenine dinucleotide

  4. Experimental determination of the specific heat capacity c sub p and the differential Joule-Thomson effect. mu. of FFC R227 (C sub 3 HF sub 7 ). Experimentelle Bestimmung der spezifischen Waermekapazitaet c sub p und des differentiellen Joule-Thomson-Effektes. mu. des chlorfreien Arbeitsstoffes R227 (C sub 3 HF sub 7 )

    Wirbser, H.; Ernst, G.; Braeuning, G. (Karlsruhe Univ. (T.H.) (Germany, F.R.). Inst. fuer Technische Thermodynamik)

    1990-01-01

    To prove the suitability of R227 (C{sub 3}HF{sub 7}) as a substitute for chlorinated hydrocarbons, exact measurements of its c{sub p} and {mu} were performed at temperatures between -20deg C and 150deg C and at pressures up to 15.0 MPa at Institut fuer Technische Thermodynamik (University of Karlsruhe). Measurements to determine the ideal share of the specific heat capacity c{sub p}{sup 0} were performed using low-pressure equipment. All other measurements were performed using high-pressure and high-temperature systems. Using the high-pressure system, the specific heat capacity c{sub p} of R227 in the liquid and supercritical phases was measured at 117 points, and the differential Joule-Thomson effect {mu} in the liquid and supercritical phases was measured at 66 points. These selectively chosen phase points allowed an easy calculation of the enthalpy function h(p, T). (orig./HW).

  5. Study of the origin of elements of the uranium-235 family observed in excess in the vicinity of the experimental nuclear EL4 reactor under dismantling. Lessons got at this day and conclusions; Etude de l'origine des elements de la famille de l'uranium-235 observes en exces dans les environs du reacteur nucleaire experimental EL4 en cours de demantelement. Enseignements retires a ce jour et conclusion

    NONE

    2007-07-01

    This study resumes the discovery of an excess of actinium 227 found around by EL4 nuclear reactor actually in dismantling. The search for the origin of this excess revealed a real inquiry of investigation during three years. Because a nuclear reactor existed in this area a particular attention will have concerned this region. The doubt became the line of conduct to find the answer to the human or natural origin of this excess. Finally and against any evidence, it appears that the origin of this phenomenon was natural, consequence of the particular local geology. The detail of the different investigations is given: search of a possible correlation with the composition of elevations constituent of lanes, search (and underlining) of new sites in the surroundings of the Rusquec pond and the Plouenez station, study of the atmospheric deposits under winds of the nuclear power plant and in the east direction, search of a possible relationship with the gaseous effluents of the nuclear power plant in the past, historical study of radioactive effluents releases in the fifty last years by the analysis of the sedimentary deposits in the Saint-Herbiot reservoir, search of a possible correlation between the excess of actinium 227 and the nuclear power plant activity; search of a possible correlation with a human activity without any relationship with the nuclear activities, search of a correlation with the underground waters, search of a correlation with the geological context, collect of information on the possible transfers in direction of the food chain, determination of the radiological composition of the underground waters ( not perturbed by human activity), search of the cause of an excess of actinium 227 in the old channel of liquid effluents release of the nuclear power plant. The results are given and discussed. And contrary to all expectations the origin of the excess of actinium 227 is completely natural. (N.C.)

  6. Chronic estrogen treatment in female transgenic (mRen2)27 hypertensive rats augments endothelium-derived nitric oxide release.

    Li, P; Ferrario, C M; Ganten, D; Brosnihan, K B

    1997-06-01

    Postmenopausal estrogen replacement therapy is associated with a reduction in cardiovascular events in women, but the mechanisms for this protection are unclear, especially in hypertensive subjects. In this study we investigated the effects of 17beta-estradiol (E2) treatment on blood pressure and endothelial function of transgenic [(mRen2)27] hypertensive and normotensive rats. Thirty female transgenic negative [Tg(-)] and hypertensive positive [Tg(+)] rats were ovariectomized and received either E2 (1.5 mg/rat, subcutaneously, for 3 weeks) or placebo. Chronic 17beta-estradiol treatment lowered mean blood pressure in both Tg hypertensive (159 +/- 4 v 145 +/- 4 mm Hg, P calcium ionophore (A23187)-induced endothelium-dependent relaxation was less potent in Tg(+) as compared to Tg(-) rats and was enhanced by E2 treatment only in Tg(+) animals. There were no differences in the vasodilator responses elicited by sodium nitroprusside. Removal of endothelium and blockade of NO production abolished the endothelium-dependent vasodilation. The selective NO synthase inhibitor, N(G)-monomethyl-L-arginine (LMMNA), was used to evaluate indirectly the basal contribution of NO in vascular rings. The response to LMMNA was attenuated in untreated Tg(+) as compared to Tg(-) rats. E2 treatment augmented the contraction response to NOS inhibition in both Tg(+) and Tg(-) rats, resulting in a response in Tg(+) rats that was no different from Tg(-) rats. These results indicate that untreated, surgically ovariectomized hypertensive rats show deficiencies in endothelial function, which can be improved by estrogen replacement.

  7. Urothelium muscarinic activation phosphorylates CBS(Ser227) via cGMP/PKG pathway causing human bladder relaxation through H2S production.

    d'Emmanuele di Villa Bianca, Roberta; Mitidieri, Emma; Fusco, Ferdinando; Russo, Annapina; Pagliara, Valentina; Tramontano, Teresa; Donnarumma, Erminia; Mirone, Vincenzo; Cirino, Giuseppe; Russo, Giulia; Sorrentino, Raffaella

    2016-08-11

    The urothelium modulates detrusor activity through releasing factors whose nature has not been clearly defined. Here we have investigated the involvement of H2S as possible mediator released downstream following muscarinic (M) activation, by using human bladder and urothelial T24 cell line. Carbachol stimulation enhances H2S production and in turn cGMP in human urothelium or in T24 cells. This effect is reversed by cysthationine-β-synthase (CBS) inhibition. The blockade of M1 and M3 receptors reverses the increase in H2S production in human urothelium. In T24 cells, the blockade of M1 receptor significantly reduces carbachol-induced H2S production. In the functional studies, the urothelium removal from human bladder strips leads to an increase in carbachol-induced contraction that is mimicked by CBS inhibition. Instead, the CSE blockade does not significantly affect carbachol-induced contraction. The increase in H2S production and in turn of cGMP is driven by CBS-cGMP/PKG-dependent phosphorylation at Ser(227) following carbachol stimulation. The finding of the presence of this crosstalk between the cGMP/PKG and H2S pathway downstream to the M1/M3 receptor in the human urothelium further implies a key role for H2S in bladder physiopathology. Thus, the modulation of the H2S pathway can represent a feasible therapeutic target to develop drugs for bladder disorders.

  8. Discovery of Soft Spectral Component and Transient 22.7s Quasi Periodic Oscillations of SAX J2103.5+4545

    Inam, S C; Swank, J H; Stark, M J

    2004-01-01

    XMM-Newton observed SAX J2103.5+4545 on January 6, 2003, while RXTE was monitoring the source. Using RXTE-PCA dataset between December 3, 2002 and January 29, 2003, the spin period and spin-up rate at the date of XMM-Newton observations were found to be $\\simeq 354.794$ s and $\\simeq 7.4\\times 10^{-13}$ Hz/s, respectively. The XMM-Newton observation revealed a quasi-periodic oscillation (QPO) corresponding to a mean period of 22.7s, the first QPO reported for this source, enabling us to estimate the Keplerian frequency at the inner radius of the disk to be $\\simeq 4.40\\times 10^{-3}$ Hz or $\\simeq 4.12\\times 10^{-3}$ Hz using a Keplerian or a beat frequency model. Using these frequencies, and a simple accretion disk model, for which the total accretion torque is similar to the material torque, we found the magnetic field of the neutron star to be $\\sim 7\\times 10^{12}$ Gauss and and the distance to the source to be $\\sim 3.2$ kpc. We also discovered a soft component modeled as a blackbody with kT $\\sim 1.90$ ...

  9. Vapor-liquid Equilibrium Properties of New Binary Mixture Refrigerant(R290+R227ea)%新型二元混合制冷剂(R290+R227ea)气液相平衡研究

    陈秀萍; 祁影霞; 赵胜喜; 张华

    2014-01-01

    混合制冷剂气液相平衡数据是新型制冷剂的热力学参数的重要组成部分。理论预测和实验测定混合工质的气液相平衡数据成为研究混合工质替代问题的一项迫切需要。本文基于量子化学理论,采用真实溶剂似导体模型( COSMO-RS)模拟了二元混合制冷剂(R290+R227ea)气液相平衡性质,模拟的结果与实验结果有很好的一致性。表明运用COSMO-RS模型预测混合制冷剂的气液相平衡是可行的。%The vapor-liquid equilibrium data is an important part of thermodynamic parameters of a new refrigerant. Theoretical predic-tions and experimental measurements of vapor-liquid equilibrium data of a new mixed working fluid become an urgent need for alternative refrigerant researches. The article is based on the theory of quantum chemistry . The vapor-liquid equilibrium properties of binary refriger-ant(R290+R227ea)were modeled by COSMO-RS simulations. The simulation results could accord with the data of experiments well. It shows that COSMO-RS simulation method is feasible to predict the vapor-liquid equilibrium properties of mixture refrigerants.

  10. Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat.

    Johnson, Megan S; DeMarco, Vincent G; Heesch, Cheryl M; Whaley-Connell, Adam T; Schneider, Rebecca I; Rehmer, Nathan T; Tilmon, Roger D; Ferrario, Carlos M; Sowers, James R

    2011-10-01

    The aim of this investigation was to evaluate sex differences in baroreflex and heart rate variability (HRV) dysfunction and indexes of end-organ damage in the TG(mRen2)27 (Ren2) rat, a model of renin overexpression and tissue renin-angiotensin-aldosterone system overactivation. Blood pressure (via telemetric monitoring), blood pressure variability [BPV; SD of systolic blood pressure (SBP)], spontaneous baroreflex sensitivity, HRV [HRV Triangular Index (HRV-TI), standard deviation of the average NN interval (SDNN), low and high frequency power (LF and HF, respectively), and Poincaré plot analysis (SD1, SD2)], and cardiovascular function (pressure-volume loop analysis and proteinuria) were evaluated in male and female 10-wk-old Ren2 and Sprague Dawley rats. The severity of hypertension was greater in Ren2 males (R2-M) than in Ren2 females (R2-F). Increased BPV, suppression of baroreflex gain, decreased HRV, and associated end-organ damage manifested as cardiac dysfunction, myocardial remodeling, elevated proteinuria, and tissue oxidative stress were more pronounced in R2-M compared with R2-F. During the dark cycle, HRV-TI and SDNN were negatively correlated with SBP within R2-M and positively correlated within R2-F; within R2-M, these indexes were also negatively correlated with end-organ damage [left ventricular hypertrophy (LVH)]. Furthermore, within R2-M only, LVH was strongly correlated with indexes of HRV representing predominantly vagal (HF, SD1), but not sympathetic (LF, SD2), variability. These data demonstrated relative protection in females from autonomic dysfunction and end-organ damage associated with elevated blood pressure in the Ren2 model of hypertension.

  11. Testing nuclear forces by polarization transfer coefficients in d(p,p)d and d(p,d)p reactions at Ep=22.7 MeV

    Evgeny Epelbaum

    2005-05-01

    The proton to proton polarization transfer coefficients K{sub x}{sup x'}, K{sub y}{sup y'}, K{sub z}{sup x'} and the proton to deuteron polarization transfer coefficients K{sub x}{sup x'}, K{sub y}{sup y'}, K{sub z}{sup x'}, K{sub x}{sup y'z'}, K{sub y}{sup z'z'}, K{sub z}{sup y'z'}, K{sub y}{sup x'z'} and K{sub y}{sup x'x'-y'y'} have been measured in d({rvec p}, {rvec p})d and d({rvec p}, {rvec d})p reactions at E{sub p}{sup lab} = 22.7 MeV, respectively. The data have been compared to predictions of modern nuclear forces obtained by solving the three-nucleon Faddeev equations in momentum space. Realistic (semi) phenomenological nucleon-nucleon potentials combined with model three-nucleon forces and modern chiral nuclear forces have been used. The AV18, CD Bonn, Nijm I and II nucleon-nucleon interactions have been applied alone or combined with the Tucson-Melbourne 99 three-nucleon force, adjusted separately for each potential to reproduce the triton binding energy. For the AV18 potential also the Urbana IX three-nucleon force have been used. In addition chiral NN potentials in the next-to-leading-order and chiral two- and three-nucleon forces in the next-to-next-to-leading-order have been applied. Only when three-nucleon forces are included a satisfactory description of all data results. For the chiral approach the restriction to the forces in the next-to-leading order is insufficient. Only when going over to the next-to-next-to-leading order one gets a satisfactory description of the data, similar to the one obtained with the (semi) phenomenological forces.

  12. The functional role of PI3K in maintenance of blood pressure and baroreflex suppression in (mRen2)27 and mRen2.Lewis rat.

    Logan, Exazevia M; Aileru, Azeez A; Shaltout, Hossam A; Averill, David B; Diz, Debra I

    2011-10-01

    The phosphatidylinositol 3-kinase (PI3K)-dependent signaling pathway in brain of spontaneously hypertensive rats, but not Wistar-Kyoto (WKY) rats, contributes to elevated mean arterial pressure (MAP). The role of PI3K in the regulation of blood pressure or autonomic function in the nucleus tractus solitarii (NTS) is yet to be established in other Ang II-dependent models of hypertension. Thus, we microinjected PI3K inhibitors, wortmannin or LY294002, into the NTS, and measured MAP, baroreflex sensitivity (BRS) for heart rate (HR) control, and HR variability (HRV) in mRen2.Lewis congenic and (mRen2)27 transgenic rats. Bilateral NTS microinjections of wortmannin (100 nmol/L; 50 nL) reduced MAP in (mRen2)27 and mRen2.Lewis rats (33 ± 5 mm Hg, n = 7, and 32 ± 6 mm Hg, n = 9, respectively) for approximately 90 minutes. Spectral and sequence analysis showed improvements in spontaneous BRS and HRV (50%-100%) after treatment in both hypertensive strains. Injections of wortmannin into NTS of Hannover Sprague-Dawley or Lewis control rats failed to alter MAP, BRS, or HRV. In mRen2.Lewis, but not in control Lewis rats, LY294002 (50 μmole/L) reduced MAP and increased BRS and HRV similar to wortmannin. Thus, the pharmacologic blockade of the PI3K signaling pathway in NTS reveals an important contribution to resting MAP and BRS in rats with overexpression of the Ren2 gene.

  13. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228

    Aleissa, Khalid A.; Almasoud, Fahad I.; Islam, Mohammed S. [Atomic Energy Research Institute, King Abdul Aziz City for Science and Technology, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); L' Annunziata, Michael F. [IAEA Expert, Montague Group, P.O. Box 5033, Oceanside, CA 92052-5033 (United States)], E-mail: mlannunziata@cox.net

    2008-12-15

    The activities of {sup 228}Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide {sup 228}Ac. The radium was pre-concentrated on MnO{sub 2} and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter {sup 228}Ra({sup 228}Ac), the daughter nuclide {sup 228}Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by {sup 228}Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9{+-}0.1% was measured for {sup 228}Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317{+-}0.013 cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1 g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of {sup 228}Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for {sup 228}Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure {sup 228}Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  14. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228.

    Aleissa, Khalid A; Almasoud, Fahad I; Islam, Mohammed S; L'Annunziata, Michael F

    2008-12-01

    The activities of (228)Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide (228)Ac. The radium was pre-concentrated on MnO(2) and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter (228)Ra((228)Ac), the daughter nuclide (228)Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by (228)Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9+/-0.1% was measured for (228)Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317+/-0.013cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of (228)Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for (228)Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure (228)Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  15. 22 CFR 227.105 - Definitions.

    2010-04-01

    ..., any communication to or appearance before an officer or employee or any agency, a Member of Congress..., association, authority, firm, partnership, society, State, and local government, regardless of whether...

  16. 49 CFR 227.121 - Recordkeeping.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating... person's representative upon written authorization by such employee; (iii) Make exposure measurement... exposure measurement records for specific locations available to regional or national labor...

  17. 49 CFR 227.119 - Training program.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating... concerning the expected range of workplace noise exposure levels associated with major categories of...

  18. 47 CFR 1.227 - Consolidations.

    2010-10-01

    ... application. (ii) Domestic public fixed and public mobile. See Rule § 21.31 of this chapter for the... as to amendments of applications. (iii) Public coast stations (Maritime mobile service). See... such action will best conduce to the proper dispatch of business and to the ends of...

  19. QTL Information Table: 227 [Q-TARO

    Full Text Available Pa-In, N., Vongsaprom, C., and Toojinda, T. (2002). Quantitative Trait Loci Associated with Leaf and Neck Blast Resistance in Recomb...inant Inbred Line Population of Rice (Oryza Sativa). DNA

  20. 49 CFR 227.5 - Definitions.

    2010-10-01

    ... second or less. Decibel (dB) means a unit of measurement of sound pressure levels. dB(A) means the sound pressure level in decibels measured on the A-weighted scale. Employee means any individual who is engaged... this part. Exchange rate means the change in sound level, in decibels, which would require halving...

  1. Reference: 227 [Arabidopsis Phenome Database[Archive

    Full Text Available biosynthetic enzymes and alpha-amylases was examined by reverse transcription-PCR (RT-PCR) and in situ hybridization.... The mRNAs of AtGA20ox2, AtGA20ox3 and AtGA3ox4 began to be detectable 5-7 d after pollination. In situ hybridization

  2. Danish Media coverage of 22/7

    Hervik, Peter; Boisen, Sophie

    2013-01-01

    When the two terrorist attacks in Norway took place and the identity of terrorist, Anders Behring Breivik (ABB) was revealed, attention turned to his network relations and shared ideas with Danish radical right wing communities, including the Danish People’s Party. In this article, we focus on ABB...

  3. 49 CFR 372.227 - Syracuse, NY.

    2010-10-01

    ... York Highway 192, thence easterly along New York Highway 192 to junction new New York Highway 48, thence northerly along new New York Highway 48 to junction New York Highway 213, thence easterly along New York Highway 213 to junction New York Highway 213A, thence easterly along New York Highway 213A...

  4. 12 CFR 227.12 - Definitions.

    2010-01-01

    ..., commission, bonus, or otherwise, including periodic payments pursuant to a pension, retirement, or disability... include: (1) Works of art; (2) Electronic entertainment equipment (other than one television and one...

  5. Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy; Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie

    Marx, Sebastian Markus

    2014-09-23

    The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.

  6. Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody

    Schwartz, J; O' Donoghue, J A; Humm, J L [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); Jaggi, J S [Bristol-Myers Squibb, Plainsboro, NJ (United States); Ruan, S; Larson, S M [Nuclear Medicine Service Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); McDevitt, M; Scheinberg, D A, E-mail: schwarj1@mskcc.org [Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065 (United States)

    2011-02-07

    Clinical therapeutic studies using {sup 225}Ac-labeled antibodies have begun. Of major concern is renal toxicity that may result from the three alpha-emitting progeny generated following the decay of {sup 225}Ac. The purpose of this study was to determine the amount of {sup 225}Ac and non-equilibrium progeny in the mouse kidney after the injection of {sup 225}Ac-huM195 antibody and examine the dosimetric consequences. Groups of mice were sacrificed at 24, 96 and 144 h after injection with {sup 225}Ac-huM195 antibody and kidneys excised. One kidney was used for gamma ray spectroscopic measurements by a high-purity germanium (HPGe) detector. The second kidney was used to generate frozen tissue sections which were examined by digital autoradiography (DAR). Two measurements were performed on each kidney specimen: (1) immediately post-resection and (2) after sufficient time for any non-equilibrium excess {sup 213}Bi to decay completely. Comparison of these measurements enabled estimation of the amount of excess {sup 213}Bi reaching the kidney ({gamma}-ray spectroscopy) and its sub-regional distribution (DAR). The average absorbed dose to whole kidney, determined by spectroscopy, was 0.77 (SD 0.21) Gy kBq{sup -1}, of which 0.46 (SD 0.16) Gy kBq{sup -1} (i.e. 60%) was due to non-equilibrium excess {sup 213}Bi. The relative contributions to renal cortex and medulla were determined by DAR. The estimated dose to the cortex from non-equilibrium excess {sup 213}Bi (0.31 (SD 0.11) Gy kBq{sup -1}) represented {approx}46% of the total. For the medulla the dose contribution from excess {sup 213}Bi (0.81 (SD 0.28) Gy kBq{sup -1}) was {approx}80% of the total. Based on these estimates, for human patients we project a kidney-absorbed dose of 0.28 Gy MBq{sup -1} following administration of {sup 225}Ac-huM195 with non-equilibrium excess {sup 213}Bi responsible for approximately 60% of the total. Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of {sup 225}Ac radioimmunotherapy.

  7. Origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department); Origine des elements de la famille de l'uranium-235 observes dans la riviere Ellez a proximite du reacteur nucleaire experimental EL4 en cours de demantelement (Mont d'Arree - departement du Finistere). Resultats et premiers constats annee 2006

    NONE

    2006-07-01

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 ({sup 227}Ac), non born by its ascendents which are {sup 235}U and {sup 231}Pa is observed. This phenomenon is characterized by mass activities superior to these ones of {sup 235}U and able to reach these ones of {sup 238}U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil ({sup 210}Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  8. 两种稀土产品中放射性核素分析研究%ANALYSIS OF RADIONUCLIDES IN TWO RARE EARTH PRODUCTS

    周程; 孙恋君

    2009-01-01

    利用高纯锗γ谱仪对两个稀土产品氯化镧和氯化钇的样品进行能谱分析,研究经湿法冶炼工艺后的稀土产品中放射性核素的活度变化.结果表明,样品中存在天然放射性钍系和锕-铀系的核素,以及天然放射性核素~(138)La和~(176)Lu,但两个样品中所含的放射性核素不相同.氯化镧产品中锕-铀系和钍系核素放射性未达平衡,其主要子体~(224)Ra和~(227)Th的含量随时间发生明显变化,约60天达到平衡;而氯化钇产品没有这种现象.%This paper describes a study on raidoactivity change of rare-earth products after hydrometallurgy technology,using HPGe gamma spectrometer to analyze two rare earth products (LaCl_3 and YCl_3).The results show that in the two samples exist natural radionuclides of thorium series and actinium-uranium series as well as other natural radionuclides 138 La and 176 Lu.In the sample of lanthanum chloride the radioactivity of actinium-uranium series and thorium series has not reached balance,the contents of their main progenies ~(226)Ra and ~(227)Th obviously changes with the time,reaching balance 60 days later,while YCl_3 keeps stability.

  9. 49 CFR 227.103 - Noise monitoring program.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating... made under typical operating conditions using: (i) A sound level meter conforming, at a minimum, to the...-weighted SLOW response. (3) All instruments used to measure employee noise exposure shall be calibrated...

  10. 49 CFR 227.105 - Protection of employees.

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION OCCUPATIONAL NOISE EXPOSURE Occupational Noise Exposure for Railroad Operating... appendix A of this part. (b) In assessing whether exposures exceed 115 dB(A), as set forth in paragraph (a) of this section and appendix A to this part, the apparent source of the noise exposures shall...

  11. 22 CFR 227.205 - Professional and technical services.

    2010-04-01

    ... to law as a condition for receiving that Federal contract, grant, loan, or cooperative agreement. (b... cooperative agreement or an extension, continuation, renewal, amendment, or modification of a Federal contract, grant, loan, or cooperative agreement if payment is for professional or technical services...

  12. Dicty_cDB: VHA227 [Dicty_cDB

    Full Text Available um chromoso... 33 7.5 AY698035_1( AY698035 |pid:none) Desmognathus marmoratus isolate 69... 33 7.5 AY612348_...1( AY612348 |pid:none) Desmognathus quadramaculatus vouch... 33 9.9 AY698038_1( AY698038 |pid:none) Desmognathus marmor...atus isolate T0... 33 9.9 AY612344_1( AY612344 |pid:none) Desmognathus marmor...atus voucher KH... 33 9.9 AY698041_1( AY698041 |pid:none) Desmognathus marmoratus isolate T0... 33 9.

  13. 1935 15' Quad #227 Aerial Photo Mosaic Index

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  14. Dicty_cDB: SFG227 [Dicty_cDB

    Full Text Available n Ankara... 35 2.1 DQ813662_67( DQ813662 |pid:none) Anticarsia gemmatalis nucleopolyh... 35 3.6 AJ306290_1( AJ306290 |pid:none) Toxoc...ara canis partial mRNA for my... 35 3.6 CP000492_904( CP000492 |pid:none) Chlorobiu

  15. Viral erythrocytic necrosis: Chapter 2.2.7

    Winton, James R.; Hershberger, Paul K.

    2014-01-01

    Viral erythrocytic necrosis (VEN), originally termed piscine erythrocytic necrosis, is a condition that has been reported to affect the red blood cells (RBCs) of many species of marine and anadromous fishes in both the Atlantic and Pacific Oceans (Nicholson and Reno 1981; Smail 1982; Wolf 1988; Dannevig and Thorud 1999). Fish with VEN may develop a severe anemia that can reduce their stamina, predispose them to other infections or increase the impact of other stressors (MacMillan et al. 1980; Nicholson and Reno 1981; Meyers et al. 1986; Haney et al. 1992) resulting in population-scale impacts in susceptible species (Hershberger et al. 2009).

  16. 12 CFR 227.11 - Authority, purpose, and scope.

    2010-01-01

    ... credit to consumers. (c) Scope. This subpart applies to all banks and their subsidiaries, except savings... Comptroller of the Currency, in the case of national banks, banks operating under the code of laws for the... in section 1(b) of the International Banking Act of 1978 (12 U.S.C. 3101). Effective Date Note: At...

  17. 40 CFR 180.227 - Dicamba; tolerances for residues.

    2010-07-01

    ... removed 0.04 Corn, sweet, stover 0.50 Cotton, undelinted seed 0.2 Grass, forage, fodder and hay, group 17, forage 125.0 Grass, forage, fodder and hay, group 17, hay 200.0 Millet, proso, forage 90.0 Millet, proso....0 Oat, straw 30.0 Rye, forage 90.0 Rye, grain 2.0 Rye, straw 30.0 Sorghum, grain, forage 3.0...

  18. Dicty_cDB: VFF227 [Dicty_cDB

    Full Text Available Ov3MCAM56B08 5', mRNA sequence. 54 3e-04 2 AW355195 |AW355195.1 PFOvAFCB597K Onchocerca volvulus adult female cDNA following ivermect...in (SAW98PF-OvAF) Onchocerca volvulus cDNA clone PFOvAFCB597 5', mRNA sequence. 54

  19. Dicty_cDB: SFF227 [Dicty_cDB

    Full Text Available donnay Vitis vinifera cDNA clone VVB158G03 5, mRNA sequence. 64 4e-07 2 CA813481 |CA813481.1 CA48LN10IF-E8 Caberne...28 |CB341828.2 CA32EN0002_IIIbF_E01 Cabernet Sauvignon Leaf - CA32EN Vitis vinife

  20. 46 CFR 10.227 - Requirements for renewal.

    2010-10-01

    ... the applicant. (v) An applicant for renewal of an endorsement as medical doctor or professional nurse... currently valid, appropriate license as physician, surgeon, or registered nurse issued under the authority of a state or territory of the United States, the Commonwealth of Puerto Rico, or the District...

  1. Dicty_cDB: SSL227 [Dicty_cDB

    Full Text Available developmental stages Lycopersicon esculentum cDNA, mRNA sequence. 34 0.79 2 BQ515661 |BQ515661.1 EST623076 Generation...60 |BQ515660.1 EST623075 Generation of a set of potato cDNA clones for microarray

  2. 7 CFR 227.30 - Responsibilities of State agencies.

    2010-01-01

    ....30 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM State Agency... nutrition or public health programs; foodservice operations for children; or community action or...

  3. 49 CFR 227.109 - Audiometric testing program.

    2010-10-01

    ... occupational noise in excess of the action level. Hearing protectors may be used as a substitute for the... hearing protectors offering greater attenuation, if necessary, and shall be required to use them. (iii)...

  4. 25 CFR 227.17 - Rates of rents and royalties.

    2010-04-01

    ... gasoline, and/or all other hydrocarbon substances produced and saved from the land leased, save and except... the Interior, be calculated on the basis of the highest price paid or offered (whether calculated on... same gravity, and gas, and/or natural gasoline, and/or all other hydrocarbon substances produced...

  5. 48 CFR 227.7103-5 - Government rights.

    2010-10-01

    ..., component, or process, including logistics support and other factors which may have relevance for a... adequate competition among the sources; or (iii) Reverse engineering, or providing items from Government... reverse engineering....

  6. Dicty_cDB: AFM227 [Dicty_cDB

    Full Text Available DKEYKEGEKKFCVS*slsn nnrshcs*sflhfgl*wslg*gri**srsicskkykigkkcn*nfriissrflxrgsgii s Translated Amino Acid seq...SRSFGDKEYKEGEKKFCVS*slsn nnrshcs*sflhfgl*wslg*gri**srsicskkykigkkcn*nfriissrflxrgsgii s Frame B: iiifieiyy*n

  7. 14 CFR 135.227 - Icing conditions: Operating limitations.

    2010-01-01

    ... OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT... aircraft that has frost, ice, or snow adhering to any rotor blade, propeller, windshield, wing, stabilizing... may take off an airplane any time conditions are such that frost, ice, or snow may reasonably...

  8. 7 CFR 227.1 - General purpose and scope.

    2010-01-01

    ... carry out a nutrition information and education program through a system of grants to State agencies to provide for (a) the nutritional training of educational and foodservice personnel, (b) the...

  9. Dicty_cDB: CHC227 [Dicty_cDB

    Full Text Available GGTA TCCCACCAGATCT sequence update 2002. 9.10 Translated Amino Acid sequence ---xxxxxxxxxxxxxxxxi*xxx...LTGKTITLE VEGSDNIENVKTKIQDKEGIPPD Translated Amino Acid sequence (All Frames) Frame A: ---xxxxxxxxxxxxxxxxi*xxx...ENVKTKIQDKEGIPPD Frame B: ---xxmxxxxxxxxxixxxfsxxxkxwyxxfcxnpxw*xynxxklkvlxxlrmlk...pkxkt kkvfhqinxvsfspvxnwrmvvlslittfkrnplsi*fsd*evvckfl*klslvkplhxk lkvvttlrm*kqkfktkkvshqi Frame C: ---xxxxxxxxxkxxsxxxlvxxxxggxxx

  10. 30 CFR 227.105 - What are the hearing procedures?

    2010-07-01

    ... conduct one or more public hearings for fact finding regarding your ability to assume the delegated... present testimony and written information in support of your proposal; (f) Other persons may attend the... you that your delegation proposal is complete, MMS will schedule a hearing on your proposal, if...

  11. 7 CFR 227.36 - Requirements of needs assessment.

    2010-01-01

    ... children and areas where nutrition education may assist in positive changes; (15) Problems encountered in..., DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING PROGRAM State Coordinator... listed below to enable State agencies to determine their nutrition education and training needs for...

  12. Dosimetric and functional analysis of 227 patients treated by permanents prostate implants; Analyse dosimetrique et fonctionnelle de 227 patients traites par implants prostatiques permanents

    Champeaux-Orange, E.; Wachter, T. [CHR, 45 - Orleans (France); Le Floch, O.; Haillot, O.; Peneau, M.; Raynaud-Bougnoux, A. [CHU, 37 - Tours (France)

    2009-10-15

    The brachytherapy of prostate by permanent implants is included in the armamentarium of localized prostate cancers with external radiotherapy and radical prostatectomy. The quality evaluation of implantation is essential for the patient and the team managing him. Our retrospective work consisted in analysing the whole of dosimetry data and urinary, digestive and sexual functional results of patients treated in our centers. conclusion: the post-implantation dosimetry analysis is essential to improve the technique and to understand the evolutions. The method of scanning evaluation is difficult but is currently the most used by its accessibility. The low urinary, rectal and sexual morbidity of the brachytherapy makes of this treatment an attractive technique for the patients should be well selected. (N.C.)

  13. Ac, La, and Ce radioimpurities in {sup 225}Ac produced in 40-200 MeV proton irradiations of thorium

    Engle, Jonathan W.; Ballard, Beau D. [Los Alamos National Laboratory, NM (United States); Weidner, John W. [Air Force Institute of Technology, Wright Patterson Air Force Base, OH (United States); and others

    2014-10-01

    Accelerator production of {sup 225}Ac addresses the global supply deficiency currently inhibiting clinical trials from establishing {sup 225}Ac's therapeutic utility, provided that the accelerator product is of sufficient radionuclidic purity for patient use. Two proton activation experiments utilizing the stacked foil technique between 40 and 200 MeV were employed to study the likely co-formation of radionuclides expected to be especially challenging to separate from {sup 225}Ac. Foils were assayed by nondestructive γ-spectroscopy and by α-spectroscopy of chemically processed target material. Nuclear formation cross sections for the radionuclides {sup 226}Ac and {sup 227}Ac as well as lower lanthanide radioisotopes {sup 139}Ce, {sup 141}Ce, {sup 143}Ce, and {sup 140}La whose elemental ionic radii closely match that of actinium were measured and are reported. The predictions of the latest MCNP6 event generators are compared with measured data, as they permit estimation of the formation rates of other radionuclides whose decay emissions are not clearly discerned in the complex spectra collected from {sup 232}Th(p,x) fission product mixtures. (orig.)

  14. Pulse-shape discrimination and energy quenching of alpha particles in Cs$_2$LiLaBr$_6$:Ce$^{3+}$

    Mesick, Katherine E; Stonehill, Laura C

    2016-01-01

    Cs$_2$LiLaBr$_6$:Ce$^{3+}$ (CLLB) is an elpasolite scintillator that offers excellent linearity and gamma-ray energy resolution and sensitivity to thermal neutrons with the ability to perform pulse-shape discrimination (PSD) to distinguish gammas and neutrons. Our investigation of CLLB has indicated the presence of intrinsic radioactive alpha background that we have determined to be from actinium contamination of the lanthanum component. We measured the pulse shapes for gamma, thermal neutron, and alpha events and determined that PSD can be performed to separate the alpha background with a moderate figure of merit of 0.98. We also measured the electron-equivalent-energy of the alpha particles in CLLB and simulated the intrinsic alpha background from $^{227}$Ac to determine the quenching factor of the alphas. A linear quenching relationship $L_{\\alpha} = E_{\\alpha} \\times q + L_0$ was found at alpha particle energies above 5 MeV, with a quenching factor $q = 0.71$ MeVee/MeV and an offset $L_0 = - 1.19$ MeVee.

  15. Development of an Ultra-Low Background Liquid Scintillation Counter for Trace Level Analysis

    Erchinger, Jennifer L.; Orrell, John L.; Aalseth, Craig E.; Bernacki, Bruce E.; Douglas, Matthew; Finn, Erin C.; Fuller, Erin S.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Panisko, Mark E.; Shaff, Sarah M.; Warren, Glen A.; Wright, Michael E.

    2015-09-01

    Low-level liquid scintillation counting (LSC) has been established as one of the radiation detection techniques useful in elucidating environmental processes and environmental monitoring around nuclear facilities. The Ultra-Low Background Liquid Scintillation Counter (ULB-LSC) under construction in the Shallow Underground Laboratory at Pacific Northwest National Laboratory aims to further reduce the MDAs and/or required sample processing. Through layers of passive shielding in conjunction with an active veto and 30 meters water equivalent overburden, the background reduction is expected to be 10 to 100 times below typical analytic low-background liquid scintillation systems. Simulations have shown an expected background of around 14 counts per day. A novel approach to the light collection will use a coated hollow light guide cut into the inner copper shielding. Demonstration LSC measurements will show low-energy detection, spectral deconvolution, and alpha/beta discrimination capabilities, from trials with standards of tritium, strontium-90, and actinium-227, respectively. An overview of the system design and expected demonstration measurements will emphasize the potential applications of the ULB-LSC in environmental monitoring for treaty verification, reach-back sample analysis, and facility inspections.

  16. 40 CFR 227.7 - Limits established for specific wastes or waste constituents.

    2010-07-01

    ..., such as benzene, xylene, carbon disulfide and toluene, may be dumped only when they are present in the waste in concentrations below their solubility limits in seawater. This provision does not apply...

  17. 19 CFR 10.227 - Verification and justification of claim for preferential treatment.

    2010-04-01

    .... United States-Caribbean Basin Trade Partnership Act Textile and Apparel Articles Under the United States..., such as purchase orders, invoices, bills of lading and other shipping documents, and customs import and... the textile or apparel article qualifies for preferential treatment. Those records must...

  18. 40 CFR 227.6 - Constituents prohibited as other than trace contaminants.

    2010-07-01

    ... regulated under the FWPCA; (5) Known carcinogens, mutagens, or teratogens or materials suspected to be carcinogens, mutagens, or teratogens by responsible scientific opinion. (b) These constituents will be... compounds identified as carcinogens, mutagens, or teratogens for which criteria have not been included...

  19. 21 CFR 1.227 - What definitions apply to this subpart?

    2010-04-01

    ...)). (8) Packaging (when used as a verb) means placing food into a container that directly contacts the... not physically present. (i) The U.S. agent acts as a communications link between FDA and the foreign facility for both emergency and routine communications. The U.S. agent will be the person FDA contacts...

  20. 48 CFR 52.227-11 - Patent Rights-Ownership by the Contractor.

    2010-10-01

    ... invention is being utilized and that its benefits are, to the extent permitted by law or Government... subject invention. The disclosure shall also identify any publication, on sale (i.e., sale or offer for... the acceptance of any manuscript describing the subject invention for publication and any on sale...

  1. Erostratus Unbound: Norway’s 22/7 Converging Frames of War

    Meret, Susi; Hervik, Peter

    2013-01-01

    The purpose of this introductory article is to set the stage for the theme issue on the 22 July 2011 terror attacks in Oslo and Utøya by mass murderer, Anders Behring Breivik. The article opens up with the historical and literary figure Erostratus to discuss the differences and similarities betwe...... in news articles in a way not unlike the media coverage (and academic analyses) of the Danish Muhammad cartoon affair...

  2. 48 CFR 1852.227-11 - Patent Rights-Retention by the Contractor (Short Form).

    2010-10-01

    ...) The Contractor may use whatever format is convenient to disclose subject inventions required in... Technology Reporting Web site http://invention.nasa.gov. (End of addition) (f)(5) The Contractor shall... other than a small business firm or nonprofit organization. (End of substitution)...

  3. 48 CFR 252.227-7015 - Technical data-Commercial items.

    2010-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text... information, regardless of the form or method of recording, of a scientific or technical nature (including... without restrictions on use, modification, reproduction, release, or further disclosure other than...

  4. 48 CFR 252.227-7024 - Notice and approval of restricted designs.

    2010-10-01

    ... structures, machines, products, materials, construction methods, and equipment that are readily available through Government or competitive commercial channels, or through standard or proven production techniques, methods, and processes. Unless approved by the Contracting Officer, the Contractor shall not produce...

  5. 48 CFR 52.227-17 - Rights in Data-Special Works.

    2010-10-01

    ... in Data—Special Works (DEC 2007) (a) Definitions. As used in this clause— Data means recorded... financial, administrative, cost or pricing, or management information. Unlimited rights means the rights...

  6. 48 CFR 52.227-14 - Rights in Data-General.

    2010-10-01

    ... appropriate alternates: Rights in Data—General (DEC 2007) (a) Definitions. As used in this clause— Computer... contract administration, such as financial, administrative, cost or pricing, or management information..., administrative, cost or pricing, or management data or other information incidental to contract...

  7. 48 CFR 52.227-20 - Rights in Data-SBIR Program.

    2010-10-01

    ... Data—SBIR Program (DEC 2007) (a) Definitions. As used in this clause— Computer database or database... financial, administrative, cost or pricing or management information. Form, fit, and function data means... include computer software or financial, administrative, cost or pricing, or management data or...

  8. 7 CFR Appendix to Part 227 - Apportionment of Funds for Nutrition Education and Training

    2010-01-01

    ... NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS NUTRITION EDUCATION AND TRAINING... Pursuant to sections 19(j) of the Child Nutrition Act of 1966, as amended (42 U.S.C. 1788), funds available... 7 Agriculture 4 2010-01-01 2010-01-01 false Apportionment of Funds for Nutrition Education...

  9. 49 CFR Appendix F to Part 227 - Calculations and Application of Age Corrections to Audiograms

    2010-10-01

    ...: Employee is a 32-year-old male. The audiometric history for his right ear is shown in decibels below... age correction). Table F-1—Age Correction Values in Decibels for Males Years Audiometric test... Correction Values in Decibels for Females Years Audiometric test frequencies(Hz) 1000 2000 3000 4000 6000...

  10. 48 CFR 1253.227-70 - Conveyance of invention rights acquired by the Government.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Conveyance of invention... invention rights acquired by the Government. The following form is prescribed as a means for contractors to report inventions made in the course of contract performance, as specified in 1227.305-4: DD Form...

  11. 48 CFR 952.227-13 - Patent rights-acquisition by the Government.

    2010-10-01

    ... following clause: Patent Rights—Acquisition by the Government (SEP 1997) (a) Definitions. Invention, as used in this clause, means any invention or discovery which is or may be patentable or otherwise... such conditions as to establish that the invention is being utilized and that its benefits are, to...

  12. 48 CFR 952.227-11 - Patent rights-retention by the contractor (short form).

    2010-10-01

    ...) Definitions—(1) Invention means any invention or discovery which is or may be patentable or otherwise... any invention means the conception of first actual reduction to practice of such invention. (3... conditions as to establish that the invention is being utilized and that its benefits are, to the...

  13. 48 CFR 52.227-13 - Patent Rights-Ownership by the Government.

    2010-10-01

    ... following clause: Patent Rights—Ownership by the Government (DEC 2007) (a) Definitions. As used in this clause— Invention means any invention or discovery that is or may be patentable or otherwise protectable... Variety Protection Act (7 U.S.C. 2321, et seq.) Made means— (1) When used in relation to any...

  14. 30 CFR 227.803 - What are the hearing procedures for terminating a State's delegation agreement?

    2010-07-01

    ... opportunity to present testimony and written information on your ability to perform your delegated functions... Director will appoint a hearing official to conduct one or more public hearings for fact finding and to... whether to terminate your delegation agreement; (b) The hearing official will contact you about...

  15. CTEPP STANDARD OPERATING PROCEDURE FOR CONDUCTING STAFF AND PARTICIPANT TRAINING (SOP-2.27)

    This SOP describes the method to train project staff and participants to collect various field samples and questionnaire data for the study. The training plan consists of two separate components: project staff training and participant training. Before project activities begin,...

  16. Cultural Resources Mitigation Along Ditch 19, Site 23DU227, Dunklin County, Missouri

    1984-06-01

    technical assistance on lithic analysis and helped in final report preparation. To Linda Scott of Palynological Analysts, I extend my appreciation for...categories. Each of the artifact categories is discussed in the following text. Prehistoric Lithic Analysis and Results Lithic materials have proven...organizes the lithic analysis so that a "comprehensive framework" for "maximizing possible understanding of h’iman behavior" was provided. To

  17. 18 CFR 367.2270 - Account 227, Obligations under capital lease-Non-current.

    2010-04-01

    ..., FEDERAL POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Other Noncurrent Liabilities § 367... Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC...

  18. Spanish-English Immersion in the Wake of California Proposition 227: Five Cases

    Linton, April

    2007-01-01

    Two-way bilingual immersion programs are noteworthy within the context of US public education because, in them, the children of immigrants are essential assets. Language-minority and English-speaking pupils are grouped together, starting in kindergarten or earlier and extending at least through grade five, with a goal of bilingual proficiency and…

  19. 上海市227名初中生营养午餐及营养知识状况调查%Nutritious Lunch and Nutrition Knowledge Among 227 Junior Middle School Students in Shanghai

    叶文博; 姚家佳; 秦晴

    2009-01-01

    Objective To learn status of dinner at school and general nutrition knowledge of students, and to provide suggestions for boosting nutritious lunch and promoting students" healthy growth. Methods 230 externs from 3 kinds (in city center, town center and ordinary town of Shanghai) of middle schools were selected for random, and questionnaire about behavior of having dinner at school, nutrition knowledge, satiofaetion and suggestion to nutritious lunch were taken a~nong them. Food consumption of nutritious luneh were analyzed. Results Menu of the lunch were monotonous and lack of green vegetables. 37.4% students left more than half of the lunch and their satisfactory rate to the lunch was only 55.1%. Conclusion The students" nutrition knowledge is not enough. Education about nutrition knowledge among students should be strengthened, except improve the quality of nutritious luneh.%目的 了解学生在校就餐现状和营养常识,为实现营养午餐促进学生健康成长提出建议.方法 随机抽取上海市中心城区、郊区中心城镇和郊区普通乡镇3所初中的230名走读生,考察在校用餐的行为并采用问卷调查的方法,了解其掌握的营养知识和对学校午餐的满意程度和建议,分析营养午餐的食品组成.结果 午餐菜谱单调,缺乏绿叶蔬菜;37.4%的学生午餐饭菜剩余50%以上;学生对营养午餐的满意率仅为55.1%.结论 学生的营养知识匮乏,除改进营养午餐的质量之外,学生营养知识教育亟待加强.

  20. 48 CFR 227.7107-1 - Architectural designs and data clauses for architect-engineer or construction contracts.

    2010-10-01

    ... designs and data clauses for architect-engineer or construction contracts. (a) Except as provided in... construction involving architect-engineer services, is to obtain a unique architectural design of a building, a... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Architectural designs...

  1. Direct liquefaction proof-of-concept program: POC bench option run 01 (227-90). Final report

    Comolli, A.G.; Pradhan, V.R.; Lee, T.L.K.; Karolkiewicz, W.F.; Popper, G.

    1996-05-01

    This report presents the results of bench-scale work, Bench Run PB-01, conducted under the DOE Proof of Concept-Bench Option Program in direct coal liquefaction at Hydrocarbon Technologies, Inc. in Lawrenceville, New Jersey. The Bench Run PB-01 was the first of nine runs planned under the POC Bench Option Contract between the US DOE and Hydrocarbon Technologies, Inc. The primary goal of this bench run was to evaluate the most successful of the process improvements concepts, evolving out of the earlier CMSL Project, for conventional direct liquefaction as well as coprocessing of a sub-bituminous Black Thunder mine coal with waste organics such as waste plastics and heavy resid. The interstage separation of light ends and gases was indeed found to reduce the overall light gas-make from the liquefaction process. The organic waste feeds such as mixed plastics and vacuum resid, employed during Bench Run PB-01, in combined processing with coal, resulted in making the overall process more hydrogen efficient by virtue of reducing the light gas make and also decreasing the hydrogen consumption from the process, while at the same time improving the yields and quality of the distillate products. A definite synergy was found during the combined processing of coal with mixtures of vacuum resid and mixed waste plastics. The application of an all dispersed catalyst conversion reactor resulted in higher feed throughput at equivalent process performance, but also necessitated the use of an in-line hydrotreater for improving the quality of IBP-400{degrees}C distillate products. The combination of HTI`s iron gel catalyst and Molyvan-A was found very effective in achieving high levels of process performance; although, in recycled form, these catalysts were not as effective as the freshly added precursors.

  2. 48 CFR 952.227-14 - Rights in data-general. (DOE coverage-alternates VI and VII)

    2010-10-01

    ... supplied by the contractor or its licensees in sufficient quantity and at reasonable prices to satisfy... are expected to take effective steps to so supply such data in the form of results obtained by their... skilled in the art of manufacturing items or performing processes of the same general type and...

  3. [Nebraska 4-H Wheat Science School Enrichment Project, Teacher/Leader Guides 213-222 and 227.

    Nebraska Univ., Lincoln. Inst. of Agriculture and Natural Resources.

    Through the 4-H Wheat Science project, students learn the importance of wheat from the complete process of growing wheat to the final product of bread. The curriculum is designed to include hands-on experiences in science, consumer education, nutrition, production economics, vocabulary, and applied mathematics. Teachers can select those units out…

  4. Specific MAP-kinase blockade protects against renal damage in homozygous TGR(mRen2)27 rats

    de Borst, MH; Navis, G; de Boer, RA; Vis, LM; van Gilst, WH; van Goor, H

    2003-01-01

    Angiotensin II (AngII) plays an important role in renal damage by acting on hemodynamics, cell-growth, proliferation, and fibrosis, mainly by effects on the AngII type 1 (AT,) receptor. The AT, receptor activates several intracellular signaling molecules such as mitogen-activated protein kinases ext

  5. [2](1,3)Adamantano[2](2,7)pyrenophane: A Hydrocarbon with a Large Dipole Moment.

    Kahl, Paul; Wagner, J Philipp; Balestrieri, Ciro; Becker, Jonathan; Hausmann, Heike; Bodwell, Graham J; Schreiner, Peter R

    2016-08-01

    The fusion of the sp(3) -hybridized parent diamondoid adamantane with the sp(2) -hybridized pyrene results in a hybrid structure with a very large dipole moment which arises from bending the pyrene moiety. Presented herein is the synthesis, study of the electronic and optical properties, as well as the dynamic behavior of this new hydrocarbon.

  6. 78 FR 9420 - Central Gulf of Mexico Planning Area (CPA) Outer Continental Shelf (OCS) Oil and Gas Lease Sale 227

    2013-02-08

    ... February 28, 2007) NH15-12 Ewing Bank (Revised November 1, 2000) NH16-04 Mobile (Revised July 1, 2011) NH16...) Coordination (6) Blocks South of Baldwin County, Alabama (7) Law of the Sea Convention Royalty Payment (8.... VII. Bidding Instructions Instructions on how to submit a bid, secure payment of the advance bonus...

  7. 77 FR 227 - Medicare Program; Payment Policies Under the Physician Fee Schedule, Five-Year Review of Work...

    2012-01-04

    ... a multi-component, inflatable penile prosthesis at the same operative session). Due to an..., minimum of 3 views), and 73630 (Radiologic examination, foot; complete, minimum of 3 views) to reflect the...) of a multi-component, inflatable penile prosthesis at the same operative session) was identified...

  8. Mouton Jean-Michel édit., Le Sinaï de la conquête arabe à nos jours, Le Caire, IFAO 870, 2001, 227 p.

    Thierry Bianquis

    2011-12-01

    Full Text Available Contributions : Katia Cytryn-Siverman, The settlement in Northern Sinai in Islamic period. Pascal Ballet, Un atelier de potiers aux « sources de Moïse » (‘Uyûn Mûsâ. Sâmî Sâlih ‘Abd al-Malik, Une inscription du sultan mamelouk Kitbuga découverte à al-Qurrays. Béatrice Dansette, Le Sinaï, lieu de solitude, centre de relations et d’échanges spirituels ? Essai d’interprétation des récits de pèlerins occidentaux au Sinaï aux derniers siècles du Moyen-Âge. Deltev Kraack, Chivalrous adventures...

  9. A Cell ELISA for the quantification of MUC1 mucin (CD227) expressed by cancer cells of epithelial and neuroectodermal origin.

    Falahat, Rana; Wiranowska, Marzenna; Gallant, Nathan D; Toomey, Ryan; Hill, Robert; Alcantar, Norma

    2015-01-01

    Quantitative analysis of MUC1, a cell membrane associated mucin, expressed by intact cells of epithelial origin previously has been limited to flow cytometry, which requires using large quantities of cells and antibodies. Here, for the first time, we report the development of a novel Cellular-based Enzyme Linked Immunosorbent Assay (Cell ELISA) to quantify the expression of MUC1 by cell lines of epithelial and neuroectodermal origin using an antibody recognizing a specific tandem repeat found in the extracellular domain of MUC1. In contrast to flow cytometry, this method requires a much lower number of cells. We report here the results obtained from two variants of this Cell ELISA in live and fixed cells. We found that the Cell ELISA in live cells was not sensitive enough to detect a difference in MUC1 levels between the normal cells and tumor cells. However, we found that Cell ELISA in fixed cells followed by whole cell staining was a dependable method of MUC1 level detection in the normal and tumor cells showing significantly higher levels of MUC1 receptor in the tumor cells when compared to the normal controls. Therefore, we conclude that the Cell ELISA in fixed cells is an efficient method for quantifying the expression of MUC1 by epithelial and neuroectodermal cancer cell lines.

  10. Retraction notice to: Artificial intelligence in pharmaceutical product formulation: Neural computing [Chem. Ind. Chem. Eng. Q. 15(4 (2009 227-236

    Ibrić Svetlana

    2011-01-01

    Full Text Available This article has been retracted at the request of the authors. The retraction has been made because the authors admitted that they took the text and rawings from the review article written by R. Rowe and E. Colbourn, Future Medicinal Chemistry 1(4 (2009 713-726, without their permission and even did not include this article in the list of references. One of the conditions of submission of a paper for publication are that authors confirm that their work is entirely originally written, someone else’s data and/or text are appropriately cited or quoted and permission has been obtained for use of copyrighted material from other sources. Therefore, the retracted article represents a severe improperly usage of the scientific publishing system. Apologies are offered to readers of the Chem. Ind. Chem. Eng. Q. that this abuse was not detected during the submission process.

    Link to the retracted article 10.2298/CICEQ0904227I

  11. Extracellular signal regulated kinase and SMAD signaling both mediate the angiotensin II driven progression towards overt heart failure in homozygous TGR(mRen2)27

    de Boer, RA; Pokharel, S; Flesch, M; van Kampen, DA; Suurmeijer, AJH; Boomsma, F; van Gilst, WH; van Veldhuisen, DJ; Pinto, YM

    2004-01-01

    Angiotensin (Ang) II is a key player in left ventricular (LV) remodeling and cardiac fibrosis. Its effects are thought to be transferred at least in part by mitogen-activated protein kinases (MAPK), transforming growth factor (TGF) beta(1), and the Smad pathway. In this study we sought to elucidate

  12. P2-27: Electrophysiological Correlates of Conscious and Unconscious Processing of Emotional Faces in Individuals with High and Low Autistic Traits

    Svjetlana Vukusic

    2012-10-01

    Full Text Available LeDoux (1996 The Emotional Brain has suggested that subconsciouss presentation of fearful emotional information is relayed to the amygdala along a rapid subcortical route. Rapid emotion processing is important because it alerts other parts of brain to emotionally salient information. It also produces immediate reflexive responses to threating stimuli in comparison to slower conscious appraisal, which is of important adaptive survival value. Current theoretical models of autism spectrum disorders (ASD have linked impairments in the processing of emotional information to amygdala dysfunction. It can be suggested that impairment in face processing found in autism may be the result of impaired rapid subconscious processing of emotional information which does not make faces socially salient. Previous studies examined subconscious processing of emotional stimuli with backward masking paradigms by using very brief presentation of emotional face stimuli proceeded by a mask. We used an event-related potential (ERP study within a backward masking paradigm with subjects with low and high autistic tendencies as measured by the Autism Spectrum Quotient (AQ questionnaire. The time course of processing of fearful and happy facial expressions and an emotionally neutral face was investigated during subliminal (16 ms and supraliminal (166 ms stimuli presentation. The task consisted of an explicit categorization of emotional and neutral faces. We looked at ERP components N2, P3a, and also N170 for differences between subjects with low ( 19 AQ.

  13. Guillem Peire de Cazals, “Be·m plagr’ueymais qu’ab vos dona·m valgues” (BdT 227.6

    Alessio Collura

    2011-12-01

    Full Text Available This paper proposes a new edition with commentary of the poem “Be·m plagr’ueymais qu’ab vos, dona, ·m valgues” by Guillem Peire de Cazals and represents a first critical and hermeneutical reassessment of the poetry of the troubadour from Cahors, that has long been neglected. The text presents the classical structure of a love-story (springtime exordium, singing brought on by love, the theme of improvement, courting with no hope of a reward, a request for mercé and invites the fin aman to be patient. The song is examined from the viewpoint of its metrical and stylistic relations to other troubadour poems (Bernart de Ventadorn, “Can par la flors josta·l vert folh” [BdT 70.41] and “La dousa votz ai auzida” [BdT 70.23] and Lanfranc Cigala, “Ioios d’amor farai de ioi senblan” [BdT 282.12], and represents an early example of the mannerisms and experimental tendencies that characterize Guillem Peire’s poems. The article also attempts to date the composition to the twenties or thirties of the 13th century.

  14. Ethyl (E-2-(2,7-dimethyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-4-ylideneacetate

    Oulemda Bassou

    2017-02-01

    Full Text Available In the title compound, C14H14O5, the two heterocyclic rings are coplanar (r.m.s. deviation = 0.008 Å, with the largest deviation from the mean plane being 0.012 (1 Å. The mean plane through the acetate group is inclined slightly with respect to the oxopyrano[4,3-b]pyran-4-yl system, as indicated by the dihedral angle of 1.70 (7° between them. Two intramolecular hydrogen bonds, completing S(6 ring motifs, are observed in the molecule. In the crystal, molecules are linked by weak C—H...O hydrogen bonds involving the same acceptor atom, forming chains propagating along the c-axis direction and enclosing R21(6 ring motifs. The chains are linked via offset π–π interactions [intercentroid distance = 3.622 (1 Å], involving inversion-related oxopyrano[4,3-b]pyran-4-yl ring systems, forming slabs parallel to the bc plane.

  15. Compte rendu d’Esquenazi (Jean-Pierre, Sociologie des œuvres. De la production à l’interprétation, Paris, Armand Colin, 2007, 227 p.

    Clément Dessy

    2008-04-01

    Full Text Available Depuis Marcel Duchamp et l’élaboration du concept de ready-made, l’art contemporain a donné de nombreux coups de canif dans une conception de l’objet artistique qui le percevait comme « unique », d’un point de vue matériel. Pourtant, l’interprétation d’une œuvre d’art – sa « signification » ou son « sens » – demeure encore subordonnée à cette pensée de la « singularité ». L’esthétique recherche dans l’œuvre même des propriétés originales qui lui sont intrinsèques. Et si, comme le suggère Esqu...

  16. Monofunctionalization of Calix[4]arene Tetracarboxylic Acid at the Upper Rim with Isothiocyanate Group: First Bifunctional Chelating Agent for Alpha-Emitter Ac-225.

    Chen, Xiaoyuan; Ji, Min; Fisher, Darrell R; Wai, Chien M

    1999-09-01

    A procedure is reported for synthesizing a novel, water-soluble bifunctional chelating agent derived from calix[4]arene. This chelate features tetracarboxylic acid groups at the lower rim as an actinium-225 ionophore, and an isothiocyanate functional group at the upper rim for labeling of the N-terminus of monoclonal antibodies through thiourea linkage.

  17. I. The metabolic properties of plutonium and allied materials

    Hamilton, J.G.

    1948-05-24

    This report on the metabolic properties of plutonium and related radioactive materials presents experimental information in the following areas: radioautographic studies; tracer studies (with tables of accumulation in tissues) of actinium, radio-zirconium, technetium, radio-rubidium, radio-germanium, beryllium, and cadmium; decontamination and bone metabolism studies; and radio-chemical isolation.

  18. CTD Data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT218-227 during 2010) (NCEI Accession 0087584)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  19. Multibeam collection for TN227: Multibeam data collected aboard Thomas G. Thompson from 2008-11-13 to 2008-11-28, departing from Apia, Western Samoa and returning to Apia, Western Samoa

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  20. Niskin Bottle Data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT218-227 during 2010 (NCEI Accession 0087596)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  1. Ursula Camba Ludlow, Imaginarios ambiguos, realidades contradictorias: conductas y representaciones de los negros y mulatos novohispanos. Siglos XVI y XVII, México D.F., COLMEX, 2008, 227 p.

    Albornoz Vásquez, María Eugenia

    2009-01-01

    Los negros y los mulatos en la historia de Iberoamérica, como tema de reflexión historiográfica, conocen hoy un protagonismo que hasta hace poco les fue esquivo, especialmente en las producciones publicadas en español. Subrayamos: no se trata de esclavos ni de esclavitud ni de situación de esclavitud, sino de individuos de origen africano, desgranados de una noción colectiva y anónima, “las castas”. En este libro se trata de explorar las ideas, las metáforas, las asociaciones simbólicas que e...

  2. Crystal structure and absolute configuration of (3aS,4S,5R,7aR-2,2,7-trimethyl-3a,4,5,7a-tetrahydro-1,3-benzodioxole-4,5-diol

    Mario A. Macías

    2015-09-01

    Full Text Available The absolute configuration of the title compound, C10H16O4, determined as 3aS,4S,5R,7aR on the basis of the synthetic pathway, was confirmed by X-ray diffraction. The molecule contains a five- and a six-membered ring that adopt twisted and envelope conformations, respectively. The dihedral angle between the mean planes of the rings is 76.80 (11° as a result of their cis-fusion. In the crystal, molecules are linked by two pairs of O—H...O hydrogen bonds, forming chains along [010]. These chains are further connected by weaker C—H...O interactions along [100], creating (001 sheets that interact only by weak van der Waals forces.

  3. Water Column Chemical Data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT199-227 during 2008-2010 (NCEI Accession 0088839)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  4. Thermosalinograph data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT219-227 during 2010 (NCEI Accession 0087988)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  5. Negociações Multilaterais do Comércio de Serviços, Intervenção Estatal Brasileira e Defesa dos Interesses Nacionais - 10.5102/uri.v4i2.227

    Fátima Faro

    2007-10-01

    Full Text Available The purpose of this article is to discuss the evolution of the multilateral negotiations focused on trade of services, as well as the Brazilian governmental politics to emphasize the development of this economic activity, and to support our participation within the bilateral and multilateral rounds of negotiation, from an individual country perspective, according to the national point of view.

  6. Behaviour of uranium series radionuclides in surface water (Crouzille, Limousin). Geochemical implications; Comportement des radionucleides des familles de l'uranium dans les eaux superficielles du site de la Crouzille (Limousin): implications geochimiques

    NONE

    2008-06-15

    Understanding natural radionuclides behaviour in surface water is a required step to achieve uranium mine rehabilitation and preserve water quality. The first objective of this thesis is to determine which are the radionuclides sources in a drinking water reservoir. The second objective is to improve the knowledge about the behaviour of uranium series radionuclides, especially actinium. The investigated site is a brook (Sagnes, Limousin, France) which floods a peat bog contaminated by a former uranium mine and which empties into the Crouzille lake. It allows studying radionuclides transport in surface water and radionuclides retention through organic substance or water reservoir. Radionuclides distribution in particulate, colloidal and dissolved phases is determined thanks to ultra-filtrations. Gamma spectrometry allows measuring almost all natural radionuclides with only two counting stages. However, low activities of {sup 235}U series radionuclides impose the use of very low background well-type Ge detectors, such as those of the Underground Laboratory of Modane (France). Firstly, this study shows that no or few radionuclides are released by the Sagnes peat bog, although its radioactivity is important. Secondly, it provides details on the behaviour of uranium series radionuclides in surface water. More specifically, it provides the first indications of actinium solubility in surface water. Actinium's behaviour is very close to uranium's even if it is a little less soluble. (author)

  7. Reclassification of English Learners

    James B. Grissom

    2004-01-01

    Ron Unz, originator of Proposition 227, claimed, prior to the passage of Prop. 227, that the five percent annual reclassification rate of English learners to fluent English proficient indicated bilingual education was a failure. Critics of Prop. 227 have countered that the annual reclassification rate has changed little since the passage of Prop. 227, indicating the new legislation had no effect on reclassification rates. Unfortunately, the annual reclassification rate does not provide a clea...

  8. 21 CFR 558.265 - Halofuginone hydrobromide.

    2010-04-01

    ...) plus bacitracin methylene disalicylate 10 to 50 grams and roxarsone 22.7 to 45.4 grams. (A) Indications... grams plus roxarsone, 22.7 to 45.4 grams. (A) Indications for use. For the prevention of coccidiosis... hydrobromide, 2.72 grams plus roxarsone, 22.7 to 45.4 grams. (A) Indications for use. For the prevention...

  9. 40 CFR 52.1679 - EPA-approved New York State regulations.

    2010-07-01

    .../72, 37 FR 19814 Part 220, Portland Cement Plants 3/14/73 11/12/81, 46 FR 55690 Part 222, Incinerators... Metal Cleaning Processes 5/7/03 1/23/04, 69 FR 3240 Part 227, Stationary Combustion Installations /section 227.2(b)(1) 5/1/72 9/22/72, 37 FR 19814 Part 227, Stationary Combustion Installations...

  10. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    P. Bernot

    2005-07-13

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this activity is to predict dissolved concentrations or solubility limits for elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) relevant to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are provided in the form of tabulated functions with pH and log fCO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. Even though selection of an appropriate set of radionuclides documented in Radionuclide Screening (BSC 2002 [DIRS 160059]) includes actinium, transport of Ac is not modeled in the total system performance assessment for the license application (TSPA-LA) model because of its extremely short half-life. Actinium dose is calculated in the TSPA-LA by assuming secular equilibrium with {sup 231}Pa (Section 6.10); therefore, Ac is not analyzed in this report. The output data from this report are fundamental inputs for TSPA-LA used to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for the actinides discussed in this report. These models cover broad ranges of environmental conditions so they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or

  11. Analysis of the Yrast Bands with q-Deformed Moment of Inertia

    FANG Xiang-Zheng; RUAN Tu-Nan

    2001-01-01

    The rigid-rotor with a q-deformed moment of inertia is introduced to describe the nuclear rotational spectra. With the representations of quantum algebra, the normal deformed and superdeformed bands are naturally differentiated by softness. The yrast normal deformed bands in rare earth and actinium regions, as well as the yrast superdeformed bands in A-190 and 150 regions are investigated. The calculated results agree with experimental data qualitatively well, and the values of the parameters are physically reasonable. This indicates that the fixed deformation, the stretching effect and the many body statistics effect are three possible dominant factors to govern nuclear rotational bands.

  12. Transition wavelengths and unresolved transition array statistics of ions with Z = 72-89

    Kilbane, D, E-mail: Deirdre.Kilbane@ucd.ie [School of Physics, University College Dublin, Belfield, Dublin 4 (Ireland)

    2011-08-28

    Potential extreme ultraviolet and soft x-ray radiation sources have been identified, using the flexible atomic code (FAC), as emission peaks arising from the 4d-4f and 4p-4d transitions in Pd-like to Rb-like ions of hafnium through actinium. The effects of configuration interaction are investigated and for increasing nuclear charge, these strong emitters are seen to separate and move to shorter wavelengths. Each source is characterized using the unresolved transition array model. They are proposed to complement the currently used nitrogen and argon sources in the 'water window', and as possible successors to tin in next-generation lithography.

  13. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  14. Purification of cerium, neodymium and gadolinium for low background experiments

    Boiko R.S.

    2014-01-01

    Full Text Available Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search, 136Ce (2β+ candidate with one of the highest Q2β. The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  15. The Technological Enhancement of Normally Occurring Radioactive Materials in Red Mud due to the Production of Alumina

    Maurice O. Miller

    2016-01-01

    Full Text Available This study investigates the level of technological enhancement of normally occurring radioactive materials (TENORM in the red mud waste due to the production of alumina in Jamaica. Technological enhancements factors (TEF were determined for the uranium, thorium, actinium series, their progenies, and the nonseries potassium-40 using gamma spectrometry. The study concluded that bauxite production technologically enhances the uranium progenies Th-234, Pb-214, Bi-214, and Pa-234 and the thorium-232 progenies Ac-228, Pb-212, and Bi-212 in red mud. The actinium series was technologically enhanced, but K-40 and the thorium daughter, Tl-208, were reduced. The spectrometric comparison of Tl-208 (at 510 keV was unexpected since its other photopeaks at 583 keV, 934 keV, and 968 keV were markedly different. An explanation for this anomaly is discussed. An explanation regarding the process of accumulation and fractionation of organically derived phosphate deposits and potassium-feldspar is offered to explain the spectrometric differences between the alumina product and its waste material, red mud.

  16. « Islamic Restorative Traditions and Their Reflections in the Post Revolutionary Criminal Justice System of Iran ». European Journal of Crime, Criminal Law and Criminal Justice, Vol. 15, N° 2, 2007, pp. 227-248.

    Engeland, Anicée Van

    2010-01-01

    L’A. s’interroge sur l’utilité sociale de punir et sur l’opportunité de « qui punir ». C’est ainsi qu’il approche le droit pénal iranien comme une réparation du criminel envers la société. Il se concentre alors sur la notion de violation du devoir moral. Le crime de qiṣāṣ (réparation pour un homicide ou pour une blessure) a selon lui cette approche du droit pénal : il s’agit de la violation d’un devoir moral et la réparation doit de ce fait être proportionnelle au mal qui a été fait à la soci...

  17. Digestible lysine requirement of Nile tilapia from 86 to 227 g fed arginine to lysine balanced dietsExigência de lisina digestível para a tilápia-do-Nilo de 87 a 226 g alimentada com dietas balanceadas para a relação arginina: lisina

    Tadeu Orlandi Xavier

    2013-09-01

    Full Text Available This study was conducted out to determine the dietary digestible lysine requirements of Nile tilapia from 87 to 226 g. Fish (n = 170; average initial weight = 86.62 ± 4.89 g were distributed 15 1000-L cages, in a completely randomized design with five treatments and three replicates, and fed extruded diets containing 0.88; 1.12; 1.36; 1.59 and 1.83% of digestible lysine, balanced to keep the arginine to lysine ratio as 1.43:1. There was no effect of the dietary lysine levels on whole body moisture and ash. By Linear Response Plateau analysis of lysine levels on daily gain, feed conversion, protein efficiency ratio and rate of protein deposition was estimated requirement of 1.31, 1.03, 1.16 and 1.31 % of lysine, respectively. A quadratic effect of lysine levels on whole body fat deposition ratio and whole body ether extract composition were observed, and the lowest values were estimated with 1.16% and 1.43% of dietary lysine, respectively. An increase of the dietary lysine levels resulted in linear increase on the fillet yield. The digestible lysine requirements of Nile tilapia (87 to 226 g is 1.31%, in diets balanced for arginine to lysine ratio.Este estudo foi realizado com o objetivo de determinar a exigência de lisina digestível em dietas para alevinos de tilápia-do-Nilo de 87 a 226 g. Os peixes (n=300; peso inicial médio = 86,62 ± 4,89 g foram distribuídos em 15 tanques-rede de 1000 L cada, em delineamento inteiramente casualizado com cinco tratamentos e três repetições e alimentados com dietas extrusadas contendo 0,88; 1,12; 1,36; 1,59 e 1,83% de lisina digestível, balanceadas para relação arginina:lisina em 1,43:1. Não foi observado efeito dos níveis de lisina na dieta sobre os teores de umidade e proteína corporal. Pela análise Linear Response Plateau dos níveis de lisina sobre o ganho de peso diário, conversão alimentar, taxa de eficiência proteica e taxa de deposição de proteína, estimou-se exigência de 1,31; 1,03; 1,16 e 1,31% de lisina digestível, respectivamente. Foi observado efeito quadrático dos níveis de lisina sobre a taxa de deposição de gordura e teor de extrato etéreo corporal, em que os menores valores dessas variáveis foram estimados com 1,16% e 1,43% de lisina, respectivamente. Com o incremento nos teores de lisina na dieta ocorreu aumento linear no rendimento de filé e nível de proteína corporal. Concluiu-se que a tilápia-do-Nilo (87 a 226 g exige 1,31% de lisina digestível, em dietas balanceadas para a relação arginina:lisina.

  18. Public Libraries in Norway Help Non-Western Immigrant Women to Integrate into Society. A Review of: Audunson, R., Essmat, S., & Aabø, S. (2011. Public libraries: A meeting place for immigrant women? Library & Information Science Research, 33(3, 220-227. doi: 10.1016/j.lisr.2011.01.003

    Kathryn Oxborrow

    2012-03-01

    Full Text Available Objectives – To discover the ways in which the public library was used by immigrant women, with a particular focus on the library as a meeting place.Design – Semi-structured qualitative interviews conducted in the participants’ native languages.Setting – Public libraries in Norway. Participants lived in one of two cities both with a population of approximately 40,000 and a somewhat lower number of immigrants than the national average.Subjects – Nine non-western women who had immigrated to Norway between 8 months and 17 years prior to the study. Three women were from Iran, Kurdistan and Afghanistan respectively. All identified themselves as public library users.Methods – Participants were interviewed in their native languages and the qualitative results were analyzed in accordance with the theoretical framework set out by the authors. The main areas of focus were the role of the library in the generation of social capital, and the library as a high intensive versus low intensive meeting place.Main Results – Participants used public libraries in various ways. In the initial stages of life in a new country they were used to observe and learn about the majority culture and language. They were also used as a safe place to openly grieve and provide comfort among close friends without fear of being seen by other fellow countrymen. Over time, participants came to use the library space in more traditional ways such as for information, social, and professional needs. The study also revealed that using public libraries built trust in the institution of libraries and librarians as employees.Conclusions – The public library plays a key role in the generation of social capital, both in terms of integrating into the majority culture through observation and spontaneous interactions (bridging social capital and connecting with others from participants’ home cultures (bonding social capital for example through the provision of social space and other links to home such as native language materials. The public library was used initially by participants as a high intensive meeting place, for meeting with friends and consoling one another. In time, however, the public library became a medium- to low-intensive meeting place, with participants engaging in library programmes or in spontaneous interactions with other library customers. Moreover, the study refutes the Swedish Library Association’s conclusion that library is used more often by immigrants that have lived in the country for long periods of time.

  19. Communication Breakdown: Librarian and Student Approaches to Virtual Reference Differ. A review of: Walter, Virginia A. and Cindy Mediavilla. “Teens Are from Neptune, Librarians Are from Pluto: An Analysis of Online Reference Transactions.” Library Trends 54.2 (2005: 209-227.

    Stephanie Hall

    2006-09-01

    Full Text Available Objective – To evaluate the effectiveness of an online reference and referral service for students (primarily those in middle school and high school seeking homework help. Design – Analysis of 114 transcripts of reference transactions. Setting – A centralized homework reference and tutor referral service provided on behalf of the California State Library by the Metropolitan Cooperative Library System. Subjects – Virtual reference librarians at a large urban library system and middle and high school students in California. Methods – One hundred fourteen virtual reference transactions recorded between October 12 and November 8, 2003 were evaluated against the Reference and User Services Association’s (RUSA “Guidelines for Behavioral Performance of Reference and Information Service Providers.” Secondly, the transcripts were subjected to discourse analysis. Main results Performance of virtual reference librarians vis‐àvis RUSA guidelines In the majority of cases, there was some evidence that librarians communicated clearly (110 out of 114 transactions. In 78 cases, it appeared that a librarian was available quickly, and in 92 of the transactions a friendly greeting was given. What was striking, however, was that in a clear majority of cases, some of the classic reference interview strategies were not employed. In 100 or more cases each, the following strategies were not observed: repeating or paraphrasing the question; helping to interpret the question; verifying mutual understanding; asking if the question has been answered; asking if the student needs more information. Furthermore, in 75 cases librarians did not probe for further information to clarify the question, while in 87 cases they did not check that information had been clearly understood. Possibly related to these findings, the researchers felt that the transcripts revealed “a conviction that homework questions are not the proper content for reference transactions” (222. In addition, librarians were found to be frequently too quick to refer students to a tutor, when a query might have been better answered as a reference question. Findings of discourse analysis In general, the virtual reference librarians used impersonal, formal language to “reinforce the professional’s superior position vis‐à‐vis the help‐seeker” (217. There were repeated attempts by the students to interject a lighter or warmer tone (using humour, emoticons, informal language, introducing a personal note, etc.. These attempts were rarely reciprocated, with librarians continuing to use impersonal language, including stock messages such as: “we are experiencing a very busy time right now,” (217; or, “I am going to send you a page which will give you some help with your homework. After we disconnect this session, click on this link and follow the instructions to be connected with a tutor. Please do not click on any links on this page until after we have disconnected” (217. In several cases librarians were preoccupied with defining their roles—for example, specifying that they could give reference help but not advice. In all, the distancing mechanisms used by librarians, combined with occasional inaccurate referrals and technical problems with the software, were seen to create an enormous potential forfrustration on the part of the student. Conclusions – The most important implication of the study was that librarians and students were worlds (or planets apart in their approach to the reference interaction. While “teens attempted to create meaningby recreating the chat discourse environment in which they were most at home”, librarians “tried to create meaning in a parallel discourse environment that duplicated as much as possible the standard impersonal protocols of a face‐to‐face reference counter” (223. One suggested way to alleviate the disconnect between librarians and students was to involve students in the planning of the services. For now, however, the authors conclude that “teens are from Neptune, librarians are from Pluto. Better services would result if they could meet somewhere closer together” (224.

  20. Primary production and sediment trap flux measurements and calculations by the Hawaii Ocean Time-series (HOT) program at Station ALOHA in the North Pacific 100 miles north of Oahu, Hawaii for Cruises HOT1-227 during 1988-2010 (NODC Accession 0089168)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Hawaii Ocean Time-series (HOT) program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii....

  1. ‘A dialogue about the art of portraiture’ Originally published as ‘Gespräch von der Bildniskunst’, Österreichische Rundschau, Volume 6, 1906, 502—516, and republished: Julius Schlosser, Präludien Vorträge und Aufsätze, Berlin: Bard 1927, 227—247. Translated with an introduction by Karl Johns

    Julius Schlosser

    2011-12-01

    Full Text Available In an unusually popular and readable dialogue form, Schlosser alludes to the classical education he takes for granted in any reader approaching his favourite ‘thorny’ questions from aesthetics and history. These involve the problems of naturalism, impressionism, portrait likeness, psychology of perception and numerous others being bandied around academic circles at the turn of the century. It is of further interest in directly referring critically to his recently deceased friend (Alois Riegl, and being written just at a moment in his career when Schlosser had been casting around the ideas of Ernst Brücke, Konrad Lange, even Henri Bergson, but had discovered the recent contribution of Benedetto Croce, which would colour his approach with an increasing intensity for the remainder of his life. He became what might be seen as the archetypical art historical theorist, but continues to distinguish himself from his successors by his greater consistency.

  2. Data from Phelan et al. 2016 (Water Air and Soil Pollution 227:84. DOI 10.1007/s11270-016-2762-x). "Assessing the effects of climate change and air pollution on soil properties and plant diversity in sugar-maple-beech-yellow birch hardwood..."

    U.S. Environmental Protection Agency — This dataset describes the simulations at two pilot sites in the northeast from 1900-2100 for several soil and plant community responses to climate and nitrogen...

  3. 225Ac and 223Ra production via 800 MeV proton irradiation of natural thorium targets.

    Weidner, J W; Mashnik, S G; John, K D; Ballard, B; Birnbaum, E R; Bitteker, L J; Couture, A; Fassbender, M E; Goff, G S; Gritzo, R; Hemez, F M; Runde, W; Ullmann, J L; Wolfsberg, L E; Nortier, F M

    2012-11-01

    Cross sections for the formation of (225,227)Ac, (223,225)Ra, and (227)Th via the proton bombardment of natural thorium targets were measured at a nominal proton energy of 800 MeV. No earlier experimental cross section data for the production of (223,225)Ra, (227)Ac and (227)Th by this method were found in the literature. A comparison of theoretical predictions with the experimental data shows agreement within a factor of two. Results indicate that accelerator-based production of (225)Ac and (223)Ra is a viable production method.

  4. Annual Report of the Chief of Engineers, U.S. Army, on Civil Works Activities 1961. Volume 1

    1961-01-01

    227, 898 1, 047 Chico, Fla_.. .---------------------------------------..A.. .127, 633 143 Chocolate , Tex... Caliente -........ Pine Canyon------------..............--.....do............ Blackwater River......... Nubanusit Brook......... Pemigewasset River

  5. The Tactical Implications of Combat Inexperience in the United States Army

    1987-11-30

    Wrigley , IL• __b.Dl1B• atfg•n (New York: Mocrin.llan, 1967), p. 403. 36. Holler, pp. 226-227, V7. Holier, pp, 227-228. 38. George C. Marshall, lbt l...Washington: Department of the Army, 1957. .51 Kellett, Anthony . Combat Motivation: The Behavior of Soldiers in Battle. Boston: Kluwer Nijhoff Publishing

  6. 78 FR 979 - Petition for Exemption; Summary of Petition Received

    2013-01-07

    ... (65 FR 19477-78). Docket: To read background documents or comments received, go to http://www..., Transport Airplane Directorate, Federal Aviation Administration, 1601 Lind Avenue SW., Renton, WA 98057-3356; email theresa.j.white@FAA.gov ; (425) 227-2956; fax: 425-227-1320; Andrea Copeland, ARM-208, Office...

  7. 78 FR 33120 - Final Interim Staff Guidance LR-ISG-2011-04; Updated Aging Management Criteria for Reactor Vessel...

    2013-06-03

    ... Evaluation Guidelines (MRP-227-A), dated December 2011 (ADAMS Accession No. ML12017A193 [Transmittal letter from the EPRI-MRP] and ADAMS Accession Nos. ML12017A194, ML12017A196, ML12017A197, ML12017A191... ensure consistency with MRP-227-A and provides a framework to ensure that PWR license renewal...

  8. Magnetic Moments and Ordered States in Pyrochlore Iridates Nd2Ir2O7 and Sm2Ir2O7 Studied by Muon-Spin Relaxation

    Asih, Retno; Adam, Noraina; Sakinah Mohd-Tajudin, Saidah; Puspita Sari, Dita; Matsuhira, Kazuyuki; Guo, Hanjie; Wakeshima, Makoto; Hinatsu, Yukio; Nakano, Takehito; Nozue, Yasuo; Sulaiman, Shukri; Ismail Mohamed-Ibrahim, Mohamad; Biswas, Pabitra Kumar; Watanabe, Isao

    2017-02-01

    Magnetic-ordered states of the pyrochlore iridates Nd2Ir2O7 (Nd227) and Sm2Ir2O7 (Sm227), showing metal-insulator transitions at 33 and 117 K, respectively, were studied by both the muon-spin-relaxation (μSR) method and density functional theory (DFT) calculations. A long-range magnetic ordering of Ir moments appeared in conjunction with the metal insulator transition, and additional long-range-ordered states of Nd/Sm moments were confirmed at temperatures below about 10 K. We found that the all-in all-out spin structure most convincingly explained the present μSR results of both Nd227 and Sm227. Observed internal fields were compared with values derived from DFT calculations. The lower limits of the sizes of magnetic moments were estimated to be 0.12 μB and 0.2 μB for Ir and Nd moments in Nd227, and 0.3 μB and 0.1 μB for Ir and Sm moments in Sm227, respectively. Further analysis indicated that the spin coupling between Ir and Nd/Sm moments was ferromagnetic for Nd227 and antiferromagnetic for Sm227.

  9. Judicial Activity Concerning Enemy Combatant Detainees: Major Court Rulings

    2010-04-01

    13 United States v. Lindh , 227 F. Supp. 2d 565...convicted for his role in the September 11, 2001, terrorist attacks, but was never officially designated as an “enemy combatant”; John Walker Lindh , thus far...instructed that the sentencing options were limited as part of an apparently successful strategy to avoid the death penalty. United States v. Lindh , 227

  10. 48 CFR 212.7003 - Technical data and computer software.

    2010-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a...

  11. 76 FR 73006 - General Motors, LLC, Grant of Petition for Decision of Inconsequential Noncompliance

    2011-11-28

    ...-2319, facsimile (202) 366-7002. Summary of GM's Petition: A total of 462,227 model year 2008, 2009 and... recall notification of noncompliance as required by 49 U.S.C. 30118 and remedying the recall... and recall responsibilities of 49 CFR part 573 for as many as 462,227 of the affected...

  12. NCBI nr-aa BLAST: CBRC-TTRU-01-1397 [SEVENS

    Full Text Available CBRC-TTRU-01-1397 ref|YP_408932.1| putative 3-phenylpropionic acid transporter [Shigella... boydii Sb227] gb|ABB67104.1| MFS transporter [Shigella boydii Sb227] YP_408932.1 0.28 20% ...

  13. NCBI nr-aa BLAST: CBRC-MMUR-01-1441 [SEVENS

    Full Text Available CBRC-MMUR-01-1441 ref|YP_408932.1| putative 3-phenylpropionic acid transporter [Shigella... boydii Sb227] gb|ABB67104.1| MFS transporter [Shigella boydii Sb227] YP_408932.1 0.32 20% ...

  14. NCBI nr-aa BLAST: CBRC-ACAR-01-1054 [SEVENS

    Full Text Available CBRC-ACAR-01-1054 ref|YP_406984.1| putative transport [Shigella boydii Sb227] sp|Q3...24V2|ENTS_SHIBS Enterobactin exporter entS gb|ABB65156.1| putative transport [Shigella boydii Sb227] YP_406984.1 1.7 27% ...

  15. NCBI nr-aa BLAST: CBRC-ETEL-01-1342 [SEVENS

    Full Text Available CBRC-ETEL-01-1342 ref|YP_408708.1| NADH dehydrogenase I chain G [Shigella boydii Sb...227] gb|ABB66880.1| NADH dehydrogenase I chain G [Shigella boydii Sb227] YP_408708.1 3.8 31% ...

  16. The Knossos Od Series. An Epigraphical Study

    Nosch, Marie-Louise Bech

    and decoration of the cloth. Moreover, scribe 227, newly identified by KILLEN and MELENA, is presented. Scribe 227 records small amounts of wool, writes in a style similar to the writing of scribes 113 and 115, and is associated with the area I1 near the North Entrance. His administrative practices thus seem...

  17. Procedimento de fiscalização : pneus reformados

    2010-01-01

    Estabelece os critérios e padroniza o procedimento para fiscalização de pneus reformados quanto ao cumprimento da Portaria Inmetro nº Portarias Inmetro 227 e 252/2006. Portarias INMETRO 227 e 252/2006

  18. bu ke kao xu shu zhe zhi zai shen shi (不可靠叙述者之再审视)

    Hansen, Per Krogh

    2008-01-01

    Kinesisk oversættelse af "Reconsidering the Unreliable Narrator" in Semiotica 165 - 1/4 2007: 227-246. Oversætter: Shang Biwu.......Kinesisk oversættelse af "Reconsidering the Unreliable Narrator" in Semiotica 165 - 1/4 2007: 227-246. Oversætter: Shang Biwu....

  19. 21 CFR 520.534 - Decoquinate.

    2010-04-01

    ...—(1) Amount. Feed 22.7 milligrams per 100 pounds of body weight (0.5 milligram per kilogram) per day... rate of 22.7 milligrams per 100 pounds body weight daily (0.5 milligram per kilogram) for at least...

  20. 77 FR 12175 - Airworthiness Directives; DASSAULT AVIATION Airplanes

    2012-02-29

    ... AD to prevent cracking of the flap tracks, which could lead to flap asymmetry and loss of control of..., 1200 New Jersey Avenue SE., Washington, DC. FOR FURTHER INFORMATION CONTACT: Tom Rodriguez, Aerospace..., Washington 98057-3356; telephone (425) 227-1137; fax (425) 227-1149. SUPPLEMENTARY INFORMATION: Discussion...

  1. EST Table: DC547495 [KAIKOcDNA[Archive

    Full Text Available DC547495 E_FL_phe-_10L12_F_0 10/09/28 94 %/227 aa ref|NP_001037003.1| transitional ...%/227 aa FBpp0154194|DgriGH20288-PA 10/08/28 65 %/223 aa C06A1.1#CE02114#WBGene00007352#locus:cdc

  2. EST Table: DC545804 [KAIKOcDNA[Archive

    Full Text Available DC545804 E_FL_phe-_04J04_F_0 10/09/28 94 %/227 aa ref|NP_001037003.1| transitional ...%/227 aa FBpp0154194|DgriGH20288-PA 10/08/28 65 %/223 aa C06A1.1#CE02114#WBGene00007352#locus:cdc

  3. EST Table: DC551457 [KAIKOcDNA[Archive

    Full Text Available DC551457 E_FL_phe-_24P13_F_0 10/09/28 94 %/227 aa ref|NP_001037003.1| transitional ...%/227 aa FBpp0154194|DgriGH20288-PA 10/08/28 65 %/223 aa C06A1.1#CE02114#WBGene00007352#locus:cdc

  4. Gclust Server: 201689 [Gclust Server

    Full Text Available 201689 OSA_@227 Cluster Sequences - 157 no annotation 1 1.00e-80 14.29 0.0 0.0 0.0 0.0 0.0 Show 2016...89 Cluster ID 201689 Sequence ID OSA_@227 Link to cluster sequences Cluster Sequences Link

  5. Dicty_cDB: [Dicty_cDB

    Full Text Available VF (Link to library) VFC227 (Link to dictyBase) - - - Contig-U16444-1 VFC227Z (Link... to Original site) - - VFC227Z 622 - - - - Show VFC227 Library VF (Link to library) Clone ID VFC227 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16444-1 Original site URL http://dict...y vs DNA Score E Sequences producing significant alignments: (bits) Value N AC116978 |AC116978.1 Dictyosteli...um discoideum chromosome 2 map 4846697-4874480 strain AX4, *** SEQUENCING IN PROGRESS ***. 876 0.0 5 AC117076 |AC117076.2 Dict

  6. Process for radioisotope recovery and system for implementing same

    Meikrantz, David H.; Todd, Terry A.; Tranter, Troy J.; Horwitz, E. Philip

    2007-01-02

    A method of recovering daughter isotopes from a radioisotope mixture. The method comprises providing a radioisotope mixture solution comprising at least one parent isotope. The at least one parent isotope is extracted into an organic phase, which comprises an extractant and a solvent. The organic phase is substantially continuously contacted with an aqueous phase to extract at least one daughter isotope into the aqueous phase. The aqueous phase is separated from the organic phase, such as by using an annular centrifugal contactor. The at least one daughter isotope is purified from the aqueous phase, such as by ion exchange chromatography or extraction chromatography. The at least one daughter isotope may include actinium-225, radium-225, bismuth-213, or mixtures thereof. A liquid-liquid extraction system for recovering at least one daughter isotope from a source material is also disclosed.

  7. Towards high-resolution laser ionization spectroscopy of the heaviest elements in supersonic gas jet expansion

    Ferrer, R.; Barzakh, A.; Bastin, B.; Beerwerth, R.; Block, M.; Creemers, P.; Grawe, H.; de Groote, R.; Delahaye, P.; Fléchard, X.; Franchoo, S.; Fritzsche, S.; Gaffney, L. P.; Ghys, L.; Gins, W.; Granados, C.; Heinke, R.; Hijazi, L.; Huyse, M.; Kron, T.; Kudryavtsev, Yu.; Laatiaoui, M.; Lecesne, N.; Loiselet, M.; Lutton, F.; Moore, I. D.; Martínez, Y.; Mogilevskiy, E.; Naubereit, P.; Piot, J.; Raeder, S.; Rothe, S.; Savajols, H.; Sels, S.; Sonnenschein, V.; Thomas, J-C; Traykov, E.; Van Beveren, C.; Van den Bergh, P.; Van Duppen, P.; Wendt, K.; Zadvornaya, A.

    2017-01-01

    Resonant laser ionization and spectroscopy are widely used techniques at radioactive ion beam facilities to produce pure beams of exotic nuclei and measure the shape, size, spin and electromagnetic multipole moments of these nuclei. However, in such measurements it is difficult to combine a high efficiency with a high spectral resolution. Here we demonstrate the on-line application of atomic laser ionization spectroscopy in a supersonic gas jet, a technique suited for high-precision studies of the ground- and isomeric-state properties of nuclei located at the extremes of stability. The technique is characterized in a measurement on actinium isotopes around the N=126 neutron shell closure. A significant improvement in the spectral resolution by more than one order of magnitude is achieved in these experiments without loss in efficiency. PMID:28224987

  8. Temporal Variations in Surface Concentrations of Terrestrial Lead 210 and Uranium 235 Radionucleides

    Yoshimori, M.

    We have started to measure the surface concentrations of terrestrial radionucleides of lead 210 and uranium 235 in Tokyo (N35, E139) in 2002. Lead 210 which is a daughter nucleus of Rn-222 (uranium series) emits 46 keV gamma-ray with a half-life of 22.4 years, while uranium 235 (actinium series) emits a gamma-ray at 186 keV with a half-life of 0.7 billion years. The present measurement of the surface concentration of lead 210 exhibits two peaks in spring and fall, similar to the beryllium 7 seasonal variations, while the uranium 235 concentration does not vary with time within statistical errors. These two terrestrial radionucleides exhibit different temporal variations on the surface. We discuss possible explanations for the differences in the temporal variations from a point of view of differences in their altitude distribution.

  9. Evaluation of total effective dose due to certain environmentally placed naturally occurring radioactive materials using a procedural adaptation of RESRAD code.

    Beauvais, Z S; Thompson, K H; Kearfott, K J

    2009-07-01

    Due to a recent upward trend in the price of uranium and subsequent increased interest in uranium mining, accurate modeling of baseline dose from environmental sources of radioactivity is of increasing interest. Residual radioactivity model and code (RESRAD) is a program used to model environmental movement and calculate the dose due to the inhalation, ingestion, and exposure to radioactive materials following a placement. This paper presents a novel use of RESRAD for the calculation of dose from non-enhanced, or ancient, naturally occurring radioactive material (NORM). In order to use RESRAD to calculate the total effective dose (TED) due to ancient NORM, a procedural adaptation was developed to negate the effects of time progressive distribution of radioactive materials. A dose due to United States' average concentrations of uranium, actinium, and thorium series radionuclides was then calculated. For adults exposed in a residential setting and assumed to eat significant amounts of food grown in NORM concentrated areas, the annual dose due to national average NORM concentrations was 0.935 mSv y(-1). A set of environmental dose factors were calculated for simple estimation of dose from uranium, thorium, and actinium series radionuclides for various age groups and exposure scenarios as a function of elemental uranium and thorium activity concentrations in groundwater and soil. The values of these factors for uranium were lowest for an adult exposed in an industrial setting: 0.00476 microSv kg Bq(-1) y(-1) for soil and 0.00596 microSv m(3) Bq(-1) y(-1) for water (assuming a 1:1 234U:238U activity ratio in water). The uranium factors were highest for infants exposed in a residential setting and assumed to ingest food grown onsite: 34.8 microSv kg Bq(-1) y(-1) in soil and 13.0 microSv m(3) Bq(-1) y(-1) in water.

  10. EST Table: FS796464 [KAIKOcDNA[Archive

    Full Text Available ar to putative lysosomal glucocerebrosidase [Tribolium castaneum] 10/09/09 32 %/334 aa FBpp0237202|DvirGJ227...milar to putative lysosomal glucocerebrosidase [Tribolium castaneum] FS796494 ffbm ...

  11. 76 FR 78082 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to Executive Order 12978

    2011-12-15

    ..., Medellin, Colombia; Carrera 52 No. 72-65 Local 106, Barranquilla, Colombia; Carrera 66B No. 34A-76 Local 227, Medellin, Colombia; Centro Comercial Cosmocentro Local 103, Cali, Colombia; Transversal 71D...

  12. Do We Know What Causes Soft Tissue Sarcomas?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  13. Guide to Quitting Smoking

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  14. Breast Reconstruction Options

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  15. What Are Lung Carcinoid Tumors?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  16. Non-Specific Immunotherapies and Adjuvants

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  17. Advance Directives

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  18. What Is Childhood Leukemia?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  19. Get Tested for Colon Cancer: Here's How

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  20. How Is Cancer of the Esophagus Diagnosed?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  1. Do We Know What Causes Ovarian Cancer?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  2. What Is Waldenstrom Macroglobulinema?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  3. How Is Breast Cancer in Men Diagnosed?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  4. Gallbladder Cancer: Surgery

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  5. What Is Uterine Sarcoma?

    ... Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every Minute ... 227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of use ...

  6. Colonization of marine snow aggregates by invertebrate zooplankton : Abundance, scaling, and possible role

    Kiørboe, Thomas

    2000-01-01

    I compiled literature observations of abundances of invertebrate zooplankters associated with marine snow aggregates in the euphotic zone. Abundances, normalized with ambient concentrations of colonizers, scale with equivalent aggregate radius raised to power 2.27. Different taxonomic groups show...

  7. Gene : CBRC-HSAP-10-0042 [SEVENS

    Full Text Available tical protein LOC729471 (LOC729471), mRNA /cds=p(1,1227) /gb=XM_001130359 /gi=113416467 /ug=Hs.693254 /len=1...227 2e-20 28% MVTSSLTVAITSLVVVITSLVVIITSFVVVTTSLVVVITSLVVVITSIAIAIATLVVVLTFTVVVLTSLVVVTTSLVMVITPPFAVITS...LGVVITSLVVIITCLVLVITALGVVITSLGVVVTSLVMVITPLVAVITPLGVVITSLVVVITSLVMVITSLTVVITSSIVVITPLVMVITSLTVIITS

  8. 78 FR 49370 - Inflation Adjustment of Maximum Forfeiture Penalties

    2013-08-14

    ... Job Creation Act of 2012, 72 FR 71131, 71134 (November 29, 2012). Accordingly, the only penalties... Records & 9,600/day. Accounts. Sec. 223(b) Dial-a-Porn 80,000/day. ] Sec. 227(e) 10,000/violation....

  9. Aquatic concentrations of chemical analytes compared to ecotoxicity estimates

    U.S. Environmental Protection Agency — We describe screening level estimates of potential aquatic toxicity posed by 227 chemical analytes that were measured in 25 ambient water samples collected as part...

  10. Õpetajate Lehe tellimiseks on vaja eriluba / Sirje Tohver

    Tohver, Sirje, 1948-

    2009-01-01

    Tallinna linnapea 29. oktoobri käskkirjaga nr PO-1/227 keelatakse linna ameti- ja nende hallatavatel asutustel, sh koolidel ja lasteaedadel tellida 2010. aastaks rohkem kui üks üleriigiline päevaleht

  11. [Wilhelm Lenz. Theodor Schiemanns Revaler Jahre (1883-1887)] / Paul Kaegbein

    Kaegbein, Paul

    2008-01-01

    Arvustus: Wilhelm Lenz. Theodor Schiemanns Revaler Jahre (1883-1887). - Ostseeprovinzen, baltische Staaten und das Nationale. Münster : LIT, 2005. Lk. 227-250. Tallinna linnaarhiivi esimesest linnaarhivaarist

  12. Data of evolutionary structure change: 1DJ2B-1ADIA [Confc[Archive

    Full Text Available 1DJ2B-1ADIA 1DJ2 1ADI B A IGSLSQVSGVLGCQWGDEGKGKLVDILAQHFDIVARCQG...LLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADI...5 PHE CA 263 LYS CA 227 TYR CA 251 1ADI... A 1ADIA 1 1ADI A 1ADI

  13. PTSD: National Center for PTSD

    Full Text Available ... 2 MB) Close × Evidence-based Treatment: What Does It Mean? Right Click here to download "Evidence-based Treatment: What Does It Mean?" (22.7 MB) Close × Prolonged Exposure for ...

  14. Get Tested for Colon Cancer: Here's How

    Full Text Available ... Statistics Center Volunteer Learning Center Follow Us Twitter Facebook Instagram Cancer Information, Answers, and Hope. Available Every ... 800.227.2345 Live Chat Follow Us Twitter Facebook Instagram help site map privacy accessibility terms of ...

  15. 77 FR 64837 - Federal Aviation Administration

    2012-10-23

    ... Federal Aviation Administration Fourth Meeting: RTCA Special Committee 227, Standards of Navigation Performance AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... 15, 2012. Kathy Hitt, Management Analyst, Business Operations Group, Federal Aviation...

  16. The Role of State and Local Jurisdictions in Identifying and Protecting Critical Infrastructure

    2013-12-01

    including, soap, detergents, hair and skin care products, cosmetics, and perfume .77 The primary method for collecting sector CIKR high-risk data is...adequately compensate for the loss of production or service; financial markets ; and CIKR supporting response and recovery.136...local partners. Figure 9. Strategy Canvas227 227 W. Chan Kim and Renée Mauborgne, Blue Ocean Strategy: How to Create Uncontested Market Space

  17. NCBI nr-aa BLAST: CBRC-DYAK-03-0009 [SEVENS

    Full Text Available CBRC-DYAK-03-0009 ref|YP_311187.1| putative transport protein [Shigella sonnei Ss04...6] ref|YP_408457.1| putative transport protein [Shigella boydii Sb227] gb|AAZ88952.1| putative transport protein [Shigella... sonnei Ss046] gb|ABB66629.1| putative transport protein [Shigella boydii Sb227] YP_311187.1 0.82 22% ...

  18. NCBI nr-aa BLAST: CBRC-DSIM-03-0006 [SEVENS

    Full Text Available CBRC-DSIM-03-0006 ref|YP_311187.1| putative transport protein [Shigella sonnei Ss04...6] ref|YP_408457.1| putative transport protein [Shigella boydii Sb227] gb|AAZ88952.1| putative transport protein [Shigella... sonnei Ss046] gb|ABB66629.1| putative transport protein [Shigella boydii Sb227] YP_311187.1 1.4 22% ...

  19. Toward a National Standards Strategy Conference Report

    1999-02-01

    a spectrum of technologies from microelectronics to microbiology . A major factor impacting standards development for medical devices is the broad...microelectronics to microbiology . Medical devices range from the very simple, such as crutches and heating pads, to the intricate and complex, like...Camara de Comercio Avenida Cuba y Ave. Ecuador Panama, PANAMA Telephone: 507/227-1728 Fax: 507/227-2677 Email: tparades@sinfo.net Libby Parker NIST

  20. Assessing the State of Procurement Knowledge Production: Implications for the Federal Government

    2011-12-01

    TCE) Microeconomic 82 15.53% Resource-Based View (RBV) Competitive 45 8.52% Social Exchange Theory Social Exchange 28 5.30% Relationship...Marketing Marketing 23 4.36% Contingency Theory Competitive 21 3.98% Resource Dependence Theory Microeconomic 18 3.41% Agency Theory Microeconomic 16 3.03...Game Theory Microeconomic 15 2.84% Organizational Learning Theories of Organizations 12 2.27% Social Network Theory Social Exchange 12 2.27

  1. Reclassification of English Learners

    James B. Grissom

    2004-07-01

    Full Text Available Ron Unz, originator of Proposition 227, claimed, prior to the passage of Prop. 227, that the five percent annual reclassification rate of English learners to fluent English proficient indicated bilingual education was a failure. Critics of Prop. 227 have countered that the annual reclassification rate has changed little since the passage of Prop. 227, indicating the new legislation had no effect on reclassification rates. Unfortunately, the annual reclassification rate does not provide a clear indicator of how long it takes students to be reclassified after entering the school system. To better estimate reclassification rates for English learners in California, cohorts were created to track the same groups of students over time. Ron Unz also claimed that test scores for immigrant students improved dramatically after the passage of Prop. 227. To evaluate his claim, average test scores were calculated by language fluency. Based on statewide data from three different cohorts tracked across four years, Prop. 227 has had no effect on reclassification rates or test scores.

  2. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    Nicholas, R.G.; Lacy, N.H.; Butz, T.R.; Brandon, N.E.

    2004-10-06

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  3. Rutherford's curriculum vitae, 1894-1907.

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus.

  4. Electronic structure and dynamics of ordered clusters with ME or RE ions on oxide surface

    Kulagin, N.A., E-mail: nkulagin@bestnet.kharkov.u [Kharkiv National University for Radio Electronics, Avenue Shakespeare 6-48, 61045 Kharkiv (Ukraine)

    2011-03-15

    Selected data of ab initio simulation of the electronic structure and spectral properties of either cluster with ions of iron, rare earth or actinium group elements have been presented here. Appearance of doped Cr{sup +4} ions in oxides, Cu{sup +2} in HTSC, Nd{sup +2} in solids has been discussed. Analysis of experimental data for plasma created ordered structures of crystallites with size of about 10{sup -9} m on surface of separate oxides are given, too. Change in the spectroscopic properties of clusters and nano-structures on surface of strontium titanate crystals discussed shortly using the X-ray line spectroscopy experimental results. - Research highlights: External influence and variation of technology induce changes in valence of nl ions in compounds. Wave function of cluster presented as anti-symmetrical set of ions wave functions. The main equation describes the self-consistent field depending on state of all electrons of cluster. Level scheme of Cr{sup 4+} ions in octo- and tetra-site corresponds to doped oxides spectra after treatment. Plasma treatment effects in appearance of systems of unit crystallites with size of about 10{sup -6}-10{sup -9} m.

  5. Cyclotron production of cesium radionuclides as analogues for francium-221 biodistribution

    Finn, R.; McDevitt, M.; Sheh, Y.; Lom, C.; Qiao, J.; Cai, S.; Burnazi, E.; Nacca, A.; Pillarsetty, N.; Jaggi, J.; Scheinberg, D.

    2005-12-01

    In our clinical investigations focussing on improved therapeutic treatment of specific tumors we have concentrated on a targeted therapy approach utilizing designed radiolabeled monoclonal antibodies as the cytotoxic reagent. The physical characteristics of the alpha particle emitting radionuclide bismuth-213 including the short half-life of 45.6 min, has shown promise for the treatment of specific cancers such as leukemias and lymphomas or micrometastatic carcinomas. In an effort to increase the cytocidal effect of the HuM195, a humanized monoclonal antibody carrier to the CD33 antigen expressed on leukemia cells, our focus is directed toward an "internal" nano-generator composed of Ac-225 radionuclide, the parent of the bismuth-213. The actinium-225 radionuclide decays through several short-lived, alpha emitting daughters including francium-221, astatine-217 and bismuth-213. In order to study the biodistribution and the pharmacokinetics of the individual daughter nuclide, francium-221, the cyclotron production and separation of cesium radionuclides, specifically cesium-132, from a natural xenon gas target was undertaken. The choice of cesium as an analogue for francium was predicated upon both elements being in Group 1A alkali metals and cesium radionuclide possesses a sufficient half-life to allow biodistribution studies to be performed. The preliminary experimental results of this investigation are presented.

  6. An Ion Exchange Study of Possible Hydridized 5f Bonding in theActinides

    Diamond, R.M.; Street, Jr., K.; Seaborg, G.T.

    1951-08-28

    A study has been made of the elution behavior of curium(III), americium(III), plutonium(III), actinium(III), plutonium(IV), neptunium(IV), uraniuM(IV), thorium(IV), neptunium(V), plutonium (VI), uranium (VI), lanthanum(III), cerium(III), europium(III), ytterbium(III), ytterium(III), strontium(II), barium(II), radium(II), cesium(I) with 3.2 M, 6.2 M, 9.3 M, and 12.2 M HCl solutions from Dowex-50 cation exchange resin columns. These elutions show that in high concentrations of hydrochloric acid the actinides form complex ions with chloride ion to a much greater extent than the lanthanides. The strengths of the tripositive actinide complex ions apparently go in the order plutonium > americium> curium, although their ionic radii also decrease in this same order. To explain these results, a partial covalent character may be ascribed to the bonding in the transuranium complex ions. It is shown that a reasonable structure for such covalent bonding involves hybridization of the 5f orbitals in the actinide elements.

  7. Tumor Immunotargeting Using Innovative Radionuclides

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  8. Liquid Scintillation Counting of Environmental Radioisotopes: A Review of the Impact of Background Reduction

    Douglas, Matthew; Bernacki, Bruce E.; Erchinger, Jennifer L.; Finn, Erin C.; Fuller, Erin S.; Hoppe, Eric W.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Orrell, John L.; Panisko, Mark E.; Warren, Glen A.; Wright, Michael E.

    2016-03-09

    Liquid scintillation counting (LSC) is a versatile and commonplace method for radiometric measurement of charged particle emitting radionuclides. The LSC method provides utility in a range of environmental science applications including hydrological studies of water transport, anthropogenic releases of radionuclides into the environment, and vertical mixing rates within oceans. Instrumental measurement background is one limiting factor of radiometric measurement sensitivity. As part of the development of a custom low background LSC system located in a shallow underground laboratory at Pacific Northwest National Laboratory, a number of measurement applications of LSC have been considered and are summarized here. The focus is on determining which aspects of such measurements would gain the greatest benefit from the reduction of LSC backgrounds by a factor of 10-100 relative to values reported in the literature. Examples of benefits include lowering the minimum detectable activity, reducing the sample size required, and shortening the elapsed timeline of the processing and analysis sequence. In particular tritium, strontium, and actinium isotopes are examined as these isotopes cover a range of requirements related to the LSC measurement method (e.g., 3H: low energy; Sr: spectral deconvolution; Ac: alpha/beta discrimination).

  9. Purification of lanthanides for double beta decay experiments

    Polischuk, O. G. [Institute for Nuclear Research, MSP 03680 Kyiv, Ukraine and INFN, Section of Rome, La Sapienza, I-00185 Rome (Italy); Barabash, A. S. [Institute of Theoretical and Experimental Physics, 117259 Moscow (Russian Federation); Belli, P. [INFN, Section of Rome Tor Vergata, I-00133 Rome (Italy); Bernabei, R. [INFN, Section of Rome Tor Vergata, I-00133 Rome, Italy and Department of Physics, University of Rome Tor Vergata, I-00133 Rome (Italy); Boiko, R. S.; Danevich, F. A.; Mokina, V. M.; Poda, D. V.; Tretyak, V. I. [Institute for Nuclear Research, MSP 03680 Kyiv (Ukraine); Cappella, F.; Incicchitti, A. [INFN, Section of Rome La Sapienza, I-00185 Rome, Italy and Department of Physics, University of Rome La Sapienza, I-00185 Rome (Italy); Cerulli, R.; Laubenstein, M.; Nisi, S. [INFN, Gran Sasso National Laboratories, I-67100 Assergi (Aq) (Italy)

    2013-08-08

    There are several potentially double beta active isotopes among the lanthanide elements. However, even high purity grade lanthanide compounds contain {sup 238}U, {sup 226}Ra and {sup 232,228}Th typically on the level of ∼ (0.1 - 1) Bq/kg. The liquid-liquid extraction technique was used to remove traces of U, Ra and Th from CeO{sub 2}, Nd{sub 2}O{sub 3} and Gd{sub 2}O{sub 3}. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe γ spectrometry at the underground Gran Sasso National Laboratories of the INFN (Italy). After the purification the radioactive contamination of gadolinium oxide by Ra and Th was decreased at least one order of magnitude. The efficiency of the approach to purify cerium oxide from Ra was on same level, while the radioactive contamination of neodymium sample before and after the purification is below the sensitivity of analytical methods. The purification method is much less efficient for chemically very similar radioactive elements like lanthanum, lutetium and actinium. R and D of the methods to remove the pollutions with improved efficiency is in progress.

  10. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin.

    Nour, S; El-Sharkawy, A; Burnett, W C; Horwitz, E P

    2004-12-01

    The objective of this work was to establish a new procedure for 228Ra determination of natural waters via preconcentration of radium on MnO2 and separation of its daughter, 228Ac, using Diphonix ion exchange resin. Following removal of potential interferences via passage through an initial Diphonix Resin column, the first daughter of 228Ra, 228Ac, is isolated by chromatographic separation via a second Diphonix column. A holding time of > 30 h for 228Ac ingrowth in between the two column separations ensures secular equilibrium. Barium-133 is used as a yield tracer. Actinium-228 is eluted from the second Diphonix Resin with 5 ml 1M 1-Hydroxyethane-1,1-diphosphonic acid (HEDPA) and quantified by addition of scintillation cocktail and LSC counting. Radium (and 133Ba) from the load and rinse solutions from the 2nd Diphonix column may be prepared for alpha spectrometry (for determination of 223Ra, 224Ra, and 226Ra) by BaSO4 microprecipitation and filtration. Decontamination tests indicate that U, Th, and Ra series nuclides do not interfere with these measurements, although high contents of 90Sr (90Y) require additional treatment for accurate measurement of 228Ra. Addition of stable Sr as a "hold back" carrier during the initial MnO2 preconcentration step was shown to remove most 90Sr interference.

  11. Soil and river sediments radionuclides monitoring at Aramar Experimental Center: an historical overview

    Segre, Nadia; Fagundes, Rosane Correa, E-mail: nadia.segre@ctmsp.mar.mil.br [Centro Tecnologico da Marinha (CTM-SP/CEA/LARE), Ipero, SP (Brazil). Centro Experimental Aramar. Lab. Radioecologico; Moraes, Marco Antonio P.V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    In order to evaluate possible effects to the environment resulting from the implementation of the Centro Tecnologico da Marinha - Centro Experimental Aramar (CTMSP-CEA) at Ipero in Sao Paulo state, Brazil, which came into operation in 1989, an Environmental Monitoring Program (PMA) was established in October, 1987. One of the aims of this program is to monitor the soil and river sediments radionuclides levels at CEA and beyond its boundary. The utilization of statistical tools to evaluate the results of radiometric environmental monitoring is a procedure required by National Nuclear Energy Commission (CNEN). The box plot is a simple statistical tool for displaying data. The central tendency and dispersion of the results as well as the observation of unusual results (outliers) in the dataset are easily visualized. Control chart is a graph that maps data and provides a picture of how a process is performing over time. A control chart always has a central line for the mean, an upper line for the upper control limit and a lower line for the lower control limit. Box plots and control charts were used to visualize the annual amount of natural uranium, lead-214, actinium-228 and lead-212 in soil and river sediment detected between 1987 and 2011, considering the measurements of all monitored places each year. This historical observation shows that, in average, the results obtained are below than the 1987-1988 levels (CEA's pre-operational) or below than the backgrounds radionuclides values. (author)

  12. Background radiation and individual dosimetry in the costal area of Tamil Nadu, India.

    Matsuda, Naoki; Brahmanandhan, G M; Yoshida, Masahiro; Takamura, Noboru; Suyama, Akihiko; Koguchi, Yasuhiro; Juto, Norimichi; Raj, Y Lenin; Winsley, Godwin; Selvasekarapandian, S

    2011-07-01

    South coast of India is known as the high-level background radiation area (HBRA) mainly due to beach sands that contain natural radionuclides as components of the mineral monazite. The rich deposit of monazite is unevenly distributed along the coastal belt of Tamil Nadu and Kerala. An HBRA site that laid in 2×7 m along the sea was found in the beach of Chinnavillai, Tamil Nadu, where the maximum ambient dose equivalent reached as high as 162.7 mSv y(-1). From the sands collected at the HBRA spot, the high-purity germanium semi-conductor detector identified six nuclides of thorium series, four nuclides of uranium series and two nuclides belonging to actinium series. The highest radioactivity observed was 43.7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1).

  13. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    NA

    2004-11-22

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this modeling activity is to predict dissolved concentrations or solubility limits for 14 elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) important to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are in the form of tabulated functions with pH and log (line integral) CO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. The output data from this report are fundamental inputs for Total System Performance Assessment for the License Application (TSPA-LA) to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for all of the actinides. These models cover broad ranges of environmental conditions so that they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or otherwise addressed.

  14. Octupole Deformed Nuclei in the Actinide Region

    Thorsteinsen, T; Rubio barroso, B; Simpson, J; Gulda, K; Sanchez-vega, M; Cocks, J; Nybo, K; Garcia borge, M; Aas, A; Fogelberg, B; Honsi, J; Smith, G; Naumann, R; Grant, I

    2002-01-01

    The aim of the present study is to investigate the limits of the "island" of octupole deformation in the mass region A=225. It is of particular importance to demonstrate experimentally the sudden disappearance of the stable octupole deformation in the presence of a well developed quadrupole field. \\\\ \\\\In order to establish the upper border line the $\\beta$ -decay chains of $^{227}$Rn $\\rightarrow ^{227}$Fr $\\rightarrow ^{227}$Ra and $^{231}$Fr $\\rightarrow ^{231}$Ra $\\rightarrow ^{231}$Ac were studied at PSB-ISOLDE using advanced fast timing and $\\gamma$-ray spectroscopy techniques. The lifetimes of the excited states have been measured in the picosecond range using the time-delayed $\\beta\\gamma\\gamma$(t) method.

  15. H+CO 2→OH+CO: Yield versus HI photolysls wavelength and OH rotational distributions under single-collision conditions and with CO 2HI complexes

    Chen, Y.; Hoffmann, G.; Oh, D.; Wittig, C.

    1989-07-01

    The title reaction was studied under single-collision conditions using 227-285 nm HI photolysis. A large decrease in the OH yield was observed as the photolysis wavelength was increased. Rotational distributions were obtained at 227, 239, 251, 263 and 280 nm. Similar yield versus wavelength data were obtained for CO 2HI complexes (233-263 nm). The OH rotational distribution obtained using 239 nm CO 2HI photolysis differs markedly from its single-collision H+CO 2 counterpart.

  16. 黑可信新闻

    2010-01-01

    英国12个月记下227起“超自然事件”超往年纪录据台湾省“今日新闻网”报道,一项27日发表的研究显示,英国在过去12个月来破纪录地记下227起让人震骇的“超自然事件”(Paranormal Events),不明真象的事件数量明显飙升。

  17. Any Peer Competitors Out There? An Economic Perspective to the Growth of Potential Peer Competitors

    1997-04-01

    Country Growth Regression,” American Economic Review , Vol. 82, (Sep 92), 942-963. 3 Levine and Renelt, “Sensitivity Analysis,” 949. 4 Vaclav Smil...for China’s Growth Performance,” American Economic Review , Vol. 86, No. 2, May 96, 227. 2 “State Run Firm to Sell More Coal at Market Prices,” Journal...29 Eduardo Borenzstein and Jonathan D. Ostry, “Accounting for China’s Growth Performance,” American Economic Review , Vol. 86, no. 2, May 96, 227. 30

  18. Gclust Server: 137076 [Gclust Server

    Full Text Available 137076 PoTR_587240 Cluster Sequences - 227 eugene3.209210001 1 1.00e-99 14.29 0.0 0....0 0.0 0.0 0.0 Show 137076 Cluster ID 137076 Sequence ID PoTR_587240 Link to cluster sequences Cluster Seque...nces Link to related sequences - Sequence length 227 Representative annotation eugene3.209210001 Number of S...es not appearing in this cluster ATH: 0 OSA: 0 PPT: 0 CRE: 0 OTAU: 0 CME: 0 GTH: 0 PFA: 0 PTR: 0 TPS: 0 Ter:

  19. Targeted Lymphoma Cell Death by Novel Signal Transduction Modifications

    2011-07-01

    binding via direct visualization . negative #41 HB22.7 Figure 11. Ramos B cells were either incubated with anti-mouse FITC (negative), HB22.7 + anti...plemented with 10% FCS and incubated with AET - activated sheep red blood cells (SRBC) for 1 h. B-cells were collected at the interface after centrifugation...prepared and incubated with cells (4 9 104 cells/ml) for 4 days. Percent cell killing was quan- tified by visual examination using trypan blue dye exclusion

  20. A Danish phonetically annotated spontaneous speech corpus (DanPASS)

    Grønnum, Nina

    2009-01-01

    A corpus is described consisting of non-scripted monologues and dialogues, recorded by 27 speakers, comprising a total of 73,227 running words, corresponding to 9 h and 46 min of speech. The monologues were recorded as one-way communication with an unseen partner where the speaker performed three...

  1. 21 CFR 520.905d - Fenbendazole powder.

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Fenbendazole powder. 520.905d Section 520.905d... DRUGS, FEEDS, AND RELATED PRODUCTS ORAL DOSAGE FORM NEW ANIMAL DRUGS § 520.905d Fenbendazole powder. (a) Specifications. (1) Each 2-ounce packet contains 2.27 grams (4 percent) of fenbendazole plus other...

  2. Faculty Perspectives and Needs in Supporting Adult English Learners: Linking Measurement to Practice

    Shore, Jane; Lentini, Jennifer; Molloy, Hillary; Steinberg, Jonathan; Holtzman, Steven

    2015-01-01

    Results from a survey of 227 adult English learner (EL) faculty in community and technical colleges in the United States reveal a clear desire to better serve adult ELs, but a lack of resources specifically designed to do so. Faculty want and need more resources to support the teaching and learning process, in the form of thoughtful assessments,…

  3. 78 FR 60798 - Airworthiness Directives; Airbus Airplanes

    2013-10-02

    ... directive (AD) for all Airbus Model A330-200, -300 and -200 Freighter series airplanes, and Model A340-200... prompted by a report that an airplane equipped with AOA sensors installed with conic plates recently... information on the availability of this material at the FAA, call 425-227-1221. Examining the AD Docket...

  4. Enhancing Autonomy-Supportive I-Thou Dialogue in Schools: Conceptualization and Socio-Emotional Effects of an Intervention Program

    Kaplan, Haya; Assor, Avi

    2012-01-01

    We present a conceptualization and a 2 year program of autonomy-supportive I-Thou dialogue among teachers and students that is based on self-determination theory (Deci and Ryan in "Psychol Inq" 11(4):227-268, 2000) and Buber's (1960) philosophy. The program was applied in 18 seventh grade classes (420 students). Findings showed: (a) increases in…

  5. Gclust Server: 120175 [Gclust Server

    Full Text Available 120175 TET_55.m00202 Cluster Sequences Related Sequences(22) 227 hypothetical prote...in chr_0_8254371_55; no annotation 1 1.00e-99 0.0 11.11 0.0 0.0 0.0 0.0 Show 120175 Cluster ID 120175 Sequen

  6. What Sexual Harassment Experiences Lead Respondents to Acknowledge Being Sexually Harassed? A Secondary Analysis of a University Survey.

    Stockdale, Margaret S.; Vaux, Alan

    1993-01-01

    According to survey responses from 933 of 1,807 undergraduates, 227 of 1,006 graduate students, and 432 of 1,372 faculty/staff, experience of sexual seduction, coercion, or imposition increased the probability of acknowledgment of having been harassed. Probability of acknowledgment was not related to gender or form of harassment. (SK)

  7. 75 FR 59411 - Defense Federal Acquisition Regulation Supplement; Patents, Data, and Copyrights (DFARS Case 2010...

    2010-09-27

    ...'' rather than ``computer software.'' The items ``design details, algorithms, processes, flow charts, formulas, and related material that describe the design, organization, or structure'' of computer software... works, and architect- engineer services was moved out of current 227.71 to entirely replace the...

  8. How the Attachment Styles Associated with Student Alienation: The Mediation Role of Emotional Well-Being

    Kocayörük, Ercan; Uzman, Ersin; Mert, Abdullah

    2014-01-01

    The present study examined emotional well-being as a mediator between parental attachment (mother and father) and student alienation. A total of 227 high school students from the city of Ankara completed the self-report measures of parental attachment, positive and negative affect, and alienation. Using structural equation modeling, a model was…

  9. 75 FR 67974 - Ocean Transportation Intermediary License Revocations

    2010-11-04

    ... Overseas Shipping. Address: 16680 Central Green Blvd, Houston, TX 77032. Date Revoked: September 23, 2010... Air Express, Inc. dba Rical Logistics. Address: One Cross Island Plaza, Suite 227, Rosedale, NY 11422... Logistics LLC. Address: 381 Blair Road, Avenel, NJ 07001. Date Revoked: October 21, 2010. Reason: Failed...

  10. Renovation of the outside lighting - Bldg. 112 zone

    GS Department

    2010-01-01

    Due to the renovation of the outside lighting, the traffic will be disrupted along “Route Feynman”. From the water tower (Bldg. 227) to Restaurant Nr. 2 (Bldg. 504) between 18 and 30 August. We recommend great caution. Thank you for your understanding. SEM Group

  11. Validation of a Questionnaire to Measure Mastery Motivation among Chinese Preschool Children

    Leung, Cynthia; Lo, S. K.

    2013-01-01

    The aim of this study was to validate a questionnaire on mastery motivation (task and effort) for use with Chinese preschool children in Hong Kong. A parent version and a teacher version were developed and evaluated. Participants included 457 children (230 boys and 227 girls) aged four and five years old, their preschool teachers and their…

  12. 24 CFR 35.1325 - Abatement.

    2010-04-01

    ...-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Methods and Standards for Lead-Paint... authorized by EPA, or by EPA at 40 CFR 745.227(e), and shall be completed by achieving clearance in... accordance with § 35.1355. Abatement of an intact, factory-applied prime coating on metal surfaces is...

  13. Participation Patterns of Korean Adolescents in School-Based Career Exploration Activities

    Rojewski, Jay W.; Lee, In Heok; Hill, Roger B.

    2014-01-01

    Variations in the school-based career exploration activities of Korean high school students were examined. Data represented 5,227 Korean adolescents in Grade 11 contained in the Korean Education Longitudinal Study of 2005, a nationally representative longitudinal database administered by the Korean Educational Development Institute. Latent class…

  14. Classifying Korean Adolescents' Career Preparedness

    Lee, In Heok; Rojewski, Jay W.; Hill, Roger B.

    2013-01-01

    Latent class analysis was used to examine the career preparation of 5,227 11th-grade Korean adolescents taken from the Korean Education Longitudinal Study of 2005 (KELS:2005). Three career preparedness groups were identified, to reflecting Skorikov's ("J Vocat Behav" 70:8-24, 2007) conceptualization of career preparedness: prepared,…

  15. Development and Validation of a Teaching Practice Scale (TISS) for Instructors of Introductory Statistics at the College Level

    Hassad, Rossi A.

    2009-01-01

    This study examined the teaching practices of 227 college instructors of introductory statistics (from the health and behavioral sciences). Using primarily multidimensional scaling (MDS) techniques, a two-dimensional, 10-item teaching practice scale, TISS (Teaching of Introductory Statistics Scale), was developed and validated. The two dimensions…

  16. Translation and Validation of the Malay Subjective Happiness Scale

    Swami, Viren

    2008-01-01

    The Subjective Happiness Scale (Lyubomirsky and Lepper, "Social Indicators Research," 46, 137-155, 1999) is a brief measure for assessing subjective happiness. The reliability and validity of the Malay version of the Subjective Happiness Scale was investigated in a community sample of 290 Chinese and 227 Malays in Malaysia. Results…

  17. Drug: D09700 [KEGG MEDICUS

    Full Text Available D09700 Drug Yttrium Y 90 clivatuzumab tetraxetan (USAN) C6496H9952N1716O2014S44. (C...assification of drugs [BR:br08310] Others Cellular antigens CD227 [HSA:4582] [KO:K06568] clivatuzumab D09700 Yttrium

  18. AcEST: DK947429 [AcEST

    Full Text Available 342 1e-92 tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbaden... 34...LEDGRTLADYNIQKESTLHLVLRLRG 227 >tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbadense PE=2 SV=1

  19. AcEST: DK953958 [AcEST

    Full Text Available 1 tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbaden... 335 8e-91 tr|B2Z6R9|B2Z6R9_GOSHI Ubiqu...97 FAGKQLEDGRTLADYNIQKESTLHLVLRLRG 227 >tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbadense P

  20. AcEST: DK953564 [AcEST

    Full Text Available lla paten... 332 1e-89 tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbaden... 330 4e-89 tr|B2Z6...LRG 227 >tr|Q6UA12|Q6UA12_GOSBA Fiber polyubiquitin OS=Gossypium barbadense PE=2 SV=1 Length = 229 Score = 3

  1. 40 CFR Appendix F to Part 50 - Measurement Principle and Calibration Procedure for the Measurement of Nitrogen Dioxide in the...

    2010-07-01

    ... use of the permeation device.) 2.2.7 Constant temperature chamber. Chamber capable of housing the NO2...) Atmospheric concentrations of these potential interferences are generally low relative to NO2 and valid NO2... flowrate. (Rotameters have been reported to operate unreliably when measuring low NO flows and are...

  2. Dynamic Federalism and Wind Farm Siting

    2014-05-18

    LYNN, ONSHORE AND OFFSHORE WIND ENERGY : AN INTRODUCTION 9 (2011).36 Id.37 Id. at 9-10.38 Id. at 12-1339 Id. at 1340 Id.41 other nations began in...OFFSHORE WIND POWER: CHALLENGES, ECONOMICS AND BENEFITS 227, 231 (Samuel D. Perkins & Melanie A. Everett eds. 2011). Offshore wind energy facilities also

  3. The Trait Emotional Intelligence Questionnaire: Internal Structure, Convergent, Criterion, and Incremental Validity in an Italian Sample

    Andrei, Federica; Smith, Martin M.; Surcinelli, Paola; Baldaro, Bruno; Saklofske, Donald H.

    2016-01-01

    This study investigated the structure and validity of the Italian translation of the Trait Emotional Intelligence Questionnaire. Data were self-reported from 227 participants. Confirmatory factor analysis supported the four-factor structure of the scale. Hierarchical regressions also demonstrated its incremental validity beyond demographics, the…

  4. Bilingualism and Mathematics Learning: Another Perspective.

    Clarkson, Philip C.; Galbraith, Peter

    1992-01-01

    The influence of English, the language used in the schooling of 227 sixth graders from Papua New Guinea, as well as the influence of their native language, Pidgin, were both found to have a significant impact upon their mathematical performance. (41 references) (JJK)

  5. 10 CFR Appendix D to Part 835 - Surface Contamination Values

    2010-01-01

    ... + Removable) 2,3 U-nat, U-235, U-238, and associated decay products 7 1,000 7 5,000 Transuranics, Ra-226, Ra-228, Th-230, Th-228, Pa-231, Ac-227, I-125, I-129 20 500 Th-nat, Th-232, Sr-90, Ra-223, Ra-224,...

  6. Enzyme-linked immunosorbent assay using a virus type-specific peptide based on a subdomain of envelope protein e(rns) for serologic diagnosis of pestivirus infections in swine

    Langedijk, J.P.; Middel, W.G.; Meloen, R.H.; Kramps, J.A.; Smit, de J.A.

    2001-01-01

    Peptides deduced from the C-terminal end (residues 191 to 227) of pestivirus envelope protein Erns were used to develop enzyme-linked immunosorbent assays (ELISAs) to measure specifically antibodies against different types of pestiviruses. The choice of the peptide was based on the modular structure

  7. Selective Exposure to Televised Aggression. Report No. 7.

    Atkin, Charles K.; And Others

    This 2-wave panel survey of young people was conducted to explore the relationship between attitudes and viewing over time, examining aggressiveness and viewing of programs portraying physical and verbal aggression. Questionnaires were administered to 227 children in the fourth, sixth, and eighth grades in 1976 and again one year later. The…

  8. Triplex PCR assay for the rapid identification of 3 major Vibrio species, Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio fluvialis.

    Vinothkumar, Kittappa; Bhardwaj, Ashima Kushwaha; Ramamurthy, Thandavarayan; Niyogi, Swapan Kumar

    2013-08-01

    A triplex PCR assay was developed for the identification of 3 major Vibrio spp., Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio fluvialis by targeting their haemolysin, haem-utilizing, and central regulatory genes, respectively. This simple, rapid, sensitive, and specific assay using cell lysates from 227 samples established its usefulness in research and epidemiology.

  9. Developing a Mobile Game Environment to Support Disadvantaged Learners

    Schmitz, Birgit; Hoffmann, Marvin; Klamma, Ralf; Klemke, Roland; Specht, Marcus

    2012-01-01

    Schmitz, B., Hoffmann, M., Klamma, R., Klemke, R., & Specht, M. (2012). Developing a Mobile Game Environment to Support Disadvantaged Learners. Proceedings of 12th IEEE International Conference on Advanced Learning Technologies (ICALT 2012) (pp. 223-227). July, 4-6, 2012, Rome, Italy: IEEE Computer

  10. Skyrocketing Scores: An Urban Legend

    Krashen, Stephen

    2005-01-01

    A new urban legend claims, "As a result of the state dropping bilingual education, test scores in California skyrocketed." Krashen disputes this theory, pointing out that other factors offer more logical explanations of California's recent improvements in SAT-9 scores. He discusses research on the effects of California's Proposition 227,…

  11. Modulation of the acute respiratory effects of winter air pollution by serum and dietary antioxidants : a panel study

    Grievink, L; Hoek, G; Boezen, HM; van't Veer, P; Brunekreef, B

    1999-01-01

    This study investigated whether a high dietary intake or serum concentration of antioxidant (pro-) vitamins could attenuate the acute respiratory effects of air pollution in panels of adults (n=227) aged 50-70 yrs with chronic respiratory symptoms in two winters starting in 1993/1994. Subjects perfo

  12. 75 FR 18240 - Comment Request: National Science Foundation-Applicant Survey

    2010-04-09

    ... technology; and (d) ways to minimize the burden of the collection of information on respondents, including through the use of automated collection techniques or other forms of information technology. DATES... by the Antarctic Science, Tourism, and Conservation Act of 1996, Public Law 104-227. Burden on...

  13. Employment, Education, and Emigration: The FYR of Macedonia

    Nikolovska, Margareta

    2004-01-01

    The transitional process of the FYR of Macedonia since independence in 1991 has been marked by a severe economic crisis, which has led to a significant increase in the levels of unemployment (31.9 percent in 2002) and poverty (22.7 percent in 2001). The turbulent situation in the Balkan region (war in the countries of the Former Yugoslavia) and…

  14. Domain Modeling: NP_004724.1 [SAHG[Archive

    Full Text Available BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE p2wita_ chr3/NP_004724.1/NP_004724.1_holo_70-544.pdb swppa 225Y,226F,227L,228G,230V,247F,248Q,321K,411Y,412I,415L BET 0 ...

  15. Explaining Changes in Mothers' Job Satisfaction Following Childbirth.

    Holtzman, Mellisa; Glass, Jennifer

    1999-01-01

    Pregnant women (n=227) interviewed before and six and 12 months after childbirth reported declines in job satisfaction following birth. The following factors positively or negatively affected satisfaction: length of leave, ability to work at home, 30 to 35-hour work week, evening/rotating shifts, supervisor support, and child-care environment. (SK)

  16. Acta Electronica Sinica (Selected Articles),

    1984-11-07

    ELECTRONICA SINICA’ (Selected Articles) ,_ "_ "-_ CD) .. " -81984 Approved for public release;, distribution unlimitd.. .ts.% .** ** **- ,-*** *o. *;. .s...34 - - - 20 FTD-ID(RST- 1227-84 EDITED TRANSLATION_ FTD-ID(RS )T- k227-84 7 November 1984 MICROFICHE NR: FTD-84-C-001068 ACTA ELECTRONICA SINICA

  17. 75 FR 36123 - Agency Information Collection Activities: Comment Request

    2010-06-24

    ...: Submission for OMB review; comment request. SUMMARY: The National Science Foundation (NSF) has submitted the following information collection requirement to OMB for review and clearance under the Paperwork Reduction... amended by the Antarctic Science, Tourism, and Conservation Act of 1996, Public Law 104-227. Burden on...

  18. Danish Rural Eye Study

    Høeg, Tracy Beth; Ellervik, Christina; Buch, Helena

    2016-01-01

    . The frequency of diabetes (HbA1c ≥ 48 mmol/mol or self-reported diagnosis) was 5.9% (n = 227), including 1.3% (n = 51) newly diagnosed in the GESUS. Of participants determined to have VI due to exudative AMD, 50% had received anti-vascular endothelial growth factor (VEGF) treatment. CONCLUSION: We report...

  19. 77 FR 61051 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    2012-10-05

    ... Eliseos No. 403 Interior 202, Colonia Polanco, Delegacion Miguel Hidalgo, Distrito Federal Codigo Postal 11550, Mexico; Calle Moliere No. 66, Colonia Palmas Polanco, Delegacion Miguel Hidalgo, Distrito Federal... Venustiano Carranza, Distrito Federal Codigo Postal 15230, Mexico; Calle Moliere No. 227, Colonia...

  20. 21 CFR 558.35 - Aklomide.

    2010-04-01

    .... (3) 25 percent aklomide, 20 percent sulfanitran, and 5 percent roxarsone. (4) 50 percent aklomide and 10 percent roxarsone. (b) Related tolerances. See § 556.30 of this chapter. (c) Conditions of use. It..., 227 grams (0.025 percent) combined with sulfanitran, 181.6 grams (0.02 percent) + roxarsone,...

  1. 78 FR 52429 - New Animal Drugs; Withdrawal of Approval of New Animal Drug Applications; Diethylcarbamazine...

    2013-08-23

    ... of NADA 098-371 for use of nicarbazin, penicillin, and roxarsone in 3-way, combination drug Type C... ``Penicillin 2.4 to 50 and roxarsone 22.7 to 45.4''. Sec. 558.460 0 7. In Sec. 558.460, remove and...

  2. 20.9.Extrapyramidal disorder

    1992-01-01

    920191 Effect of 6-hydroxydopamine oncerebral catecholamines,lipid peroxidationand antioxidant enzymes in rat-concernedwith pathogensis of Parkinson’s disease.LIANG Liping (梁立平),JIANG Dehua (江德华).Dept Neurol,Neurolgic Instit,Tianjing,300052.Chin J Neurol and Psychiat 1991; 24 (4): 223-227.As an animal model of human Parkinson’s

  3. Reference: AT1BOX [PLACE

    Full Text Available AT1BOX Ueda T, Pichersky E, Malik VS, Cashmore AR The level of expression of the to...mato rbcs-3A gene is modulated by a far-upstream promoter element in a developmentary regulated manner. Plant Cell 1:217-227 (1989) PubMed: 2535544; GenBank: S44160; ...

  4. 223Ra levels fed in the 223Fr β decay

    Abdul-Hadi, A.; Barci, V.; Weiss, B.; Maria, H.; Ardisson, G.; Hussonnois, M.; Constantinescu, O.

    1993-01-01

    The 223Fr β decay was reinvestigated using high-resolution single γ spectrometry as well as γ-γ coincidence techniques. For single γ-spectra measurements, radiochemically pure 223Fr sources were obtained by chromatographic separation from a 75 MBq activity 227Ac parent source and continuously purified of 223Ra and daughters. The analysis of the γ spectra of 30 sources showed the existence of 131 γ lines, of which 87 are reported for the first time in the 223Fr β decay although many of them are observed following the 227Th α decay. The 223Fr half-life was remeasured and found to be T1/2=22.00+/-0.07 min. γ-γ-t coincidence measurements were also carried out with 223Fr purified sources. The 223Ra level scheme was built on the basis of our γ data, as well as 227Th α-decay data. Among the 32 excited 223Ra levels, of which 22 were also known from 227Th α decay, 13 are newly reported from 223Fr β decay. Low energy levels (E<400 keV) may be classified as parity doublet bands according to the predictions of the reflection asymmetric rotor model. Above a 700 keV gap, a coexistence of symmetric and asymmetric shapes including both static and dynamic octupole correlations is suggested.

  5. Diurnal Patterns of Photosynthesis, Chlorophyll Fluorescence, and PRI to Evaluate Water Stress in the Invasive Species, Elaeagnus umbellata Thunb

    2010-01-01

    effective quantum yield of pho- tosystem II: DF=F0m ¼ F0m Fs =F0m 238 Trees (2010) 24:237–245 123 Leaf xylem pressure potentials (W) were...with ontogenic changes in water limited Chenopodium quinoa leaves. Photosynthetica 40:227–232 Yates ED, Levia DP Jr, Williams CL (2004) Recruitment of

  6. Dicty_cDB: Contig-U11084-1 [Dicty_cDB

    Full Text Available 228 4e-58 AF219475_1( AF219475 |pid:none) Carabus albrechti albrechti phosph... ...ninus isolate YAC203a ... 227 1e-57 AF219474_1( AF219474 |pid:none) Carabus albrechti okumurai phospho... 22

  7. The Good, The Bad, and The Ugly: Selecting and Vetting Indigenous Leaders

    2013-12-01

    MAGSAYSAY? Ramon Magsaysay was born in 1907, in Iba, Zambles Province, on the northern Island of Luzon in the Philippines. Magsaysay’s maternal and...wore an outfit that represented a blend of Pashtun, Tajik, and Uzbek traditional dress , physically symbolizing a unified Afghanistan.227 Also, he

  8. Trahviüksused Teises maailmasõjas / Rain Leisi

    Leisi, Rain

    2008-01-01

    Trahviüksustest, vanglatest ja koonduslaagritest, kuhu saadeti süütegusid toime pannud sõjaväelased Teise Maailmasõja ajal Saksamaal ja Venemaal. Lisatud: [Jossif Stalini 28. juuli 1942 käskkiri nr. 227] ; käskkirjas nr. 277 käskis Stalin

  9. Mutations in Danish patients with long QT syndrome and the identification of a large founder family with p.F29L in KCNH2

    Christiansen, Michael; Hedley, Paula L; Theilade, Juliane;

    2014-01-01

    , in 31.2% of cases, was based on the type of mutation identified (nonsense, insertion/deletion, frameshift or splice-site). Functional data was available for 22.7% of the missense mutations. None of the mutations were found in 364 Danish alleles and only three, all functionally characterised, were...

  10. Convergent and Divergent Validity of the Devereux Student Strengths Assessment

    Nickerson, Amanda B.; Fishman, Callen

    2009-01-01

    This study assessed the convergent and divergent validity of the Devereux Student Strengths Assessment (DESSA; LeBuffe, Shapiro, & Naglieri, 2008). A total of 227 (n = 94 teachers, n = 133 parents) raters completed the DESSA, in addition to the Behavioral and Emotional Rating Scales-2 (BERS-2; Epstein, 2004) and/or the Behavior Assessment…

  11. A revised psychoticism scale for the revised Eysenck personality questionnaire: a study among clergy.

    Francis, L J; Robbins, M; Louden, S H; Haley, J M

    2001-06-01

    The psychometric properties of an improved 6-item form of the Eysenck Psychoticism scale are examined among three samples of clergy, 1,227 Anglican clergywomen, 1,468 Roman Catholic male priests, and 1,321 male and female Methodist ministers. On the basis of these data the scale is commended for further use.

  12. Dicty_cDB: Contig-U15051-1 [Dicty_cDB

    Full Text Available 6726_227( AP006726 |pid:none) Klebsiella pneumoniae NTUH-K2044... 60 1e-07 AY328010_3( AY328010 |pid:none) Symbiont bacterium of Paed...erus fus... 58 6e-07 AL939122_261( AL939122 |pid:none) S

  13. On a Method of Statistical Business-Cycle Research; a reply (to Keynes)

    J. Tinbergen (Jan)

    1940-01-01

    textabstractAlso published in: A.H. Hansen and R.V. Clemence (Eds), Readings on Business Cycles and National Income, Allen & Unwin, London, 1953, pp. 341-354, in: Adrian C. Darnell (Ed), The History of Econometrics Vol. 2, Edward Elgar, Aldershot, 1994, pp. 214-227 and in: Dale J. Poirier (Ed), The

  14. Differentiation of PSRA due to Group A and due to Nongroup A Streptococci in Patients with Early Arthritis and Elevated Antisteptolysin-O at Presentation

    T. L. Th. A. Jansen

    2009-01-01

    serological criterium ASO/antiDNaseB ratio <1.4 and excluding a clinical criterium on chronicity/recurrency of arthritis: likelihood ratio for a positive test 7.9 [95% confidence interval (95%CI: 2.7–22.7], for a negative test 0.06 [95%CI: 0.009–0.39].

  15. 48 CFR 3427.471 - Paperwork Reduction Act clause.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Paperwork Reduction Act... Copyrights 3427.471 Paperwork Reduction Act clause. The contracting officer shall insert the clause in 3452.227-71, Paperwork Reduction Act, in all solicitations and contracts....

  16. Evaluation of the Fake Resistance of a Forced-choice Paired-comparison Computer Adaptive Personality Measure

    2008-08-01

    C. C., & Hunt, S. T. (2002). How effective are people at faking on personality questionnaires? Personality and Individual Differences , 32, 247-256...on personality measures. Personality and Individual Differences , 24 (2), 217-227. 15 Mueller-Hanson, R., Heggestad, E. D., & Thornton, III, G

  17. Himalayan Households, Tamang Demography and Domestic Process

    Prakash Prasad Sapkota

    2010-02-01

    Full Text Available Thomes E. Fricke 1981, Himalayan Households, Tamang Demography and Domestic Process, Book Faith India, 1993 ( pp 227 Price 300 Rs DOI: 10.3126/dsaj.v3i0.2789 Dhaulagiri Journal of Sociology and Anthropology Vol.3 2009 201-206

  18. Beyond Brain Blobs: Machine Learning Classifiers as Instruments for Analyzing Functional Magnetic Resonance Imaging Data

    2007-12-01

    Francisco Pereira was supported by a PRAXIS XXI scholarship from Fundacão para a Ciência e Tecnologia , Portugal, (III Quadro Comunitário de Apoio... Medicine and Biology Magazine, 25 (2):27–41, 2006. 1, 2.2.5 195 [65] S. C. Strother, J. Anderson, L. K. Hansen, U. Kjems, R. Kustra, J. Siditis, S

  19. Clinicopathologic factors identify sporadic mismatch repair-defective colon cancers

    Halvarsson, Britta; Anderson, Harald; Domanska, Katarina

    2008-01-01

    were linked to MMR status based on immunostaining and BRAF mutation status.MMR defects were identified in 22.7% of the tumors, with 46 classified as sporadic. When the clinical parameters of age, sex, and proximal tumor location were combined with the morphologic features with the highest relative...

  20. Rose Atoll Site 29P 3/9/2006 43-44M

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Rose Atoll, site 29P (14 32.227S, 168 09.122W), between 43 and 44 meters along a permanent transect.

  1. Alkalispirochaeta cellulosivorans gen. nov., sp. nov., a cellulose-hydrolysing, alkaliphilic, halotolerant bacterium isolated from the gut of a wood-eating cockroach (Cryptocercus punctulatus), and reclassification of four species of Spirochaeta as new combinations within Alkalispirochaeta gen. nov.

    Sravanthi, T; Tushar, L; Sasikala, Ch; Ramana, Ch V

    2016-04-01

    An obligately anaerobic spirochaete designated strain JC227T was isolated from the gut of a wood-eating cockroach, Cryptocercus punctulatus (Scudder), from the Rann of Kutch, Gujarat, India. Strain JC227T was Gram-stain-negative, mesophilic, halotolerant and alkaliphilic. Based on 16S rRNA gene sequence analysis, strain JC227T belongs to the genus Spirochaeta, with Spirochaeta sphaeroplastigenens JC133T (99.51%), S. odontotermitis JC202T (99.30%), S. alkalica Z-7491T (99.10%), S. americana (98.54%) and other members of the genus Spirochaeta (gen. nov., sp. nov. is proposed. The type strain of Alkalispirochaeta cellulosivorans is JC227T (=KCTC 15343T=NBRC 110105T). We also propose the reclassification of Spirochaeta sphaeroplastigenens, Spirochaeta odontotermitis, Spirochaeta alkalica and Spirochaeta americana as Alkalispirochaeta sphaeroplastigenens comb. nov. (type strain JC133T=KCTC 15220T=NBRC 109056T), Alkalispirochaeta odontotermitis comb. nov. (type strain JC202T=KCTC 15324T=NBRC 110104T), Alkalispirochaeta alkalica comb. nov. (type strain Z-7491T=DSM 8900T=ATCC 700262T) and Alkalispirochaeta americana comb. nov. (type strain ASpG1T=ATCC BAA-392T=DSM 14872T). The type species of Alkalispirochaeta gen. nov. is Alkalispirochaeta alkalica comb. nov.

  2. Cold temperature disinfestation of bagged flour

    We conducted studies using a commercial freezer maintained at -17.8°C to determine the time needed to kill Tribolium castaneum eggs in a pallet of flour. Each bag weighed 22.7 kg, and there were 5 bags in each of 10 layers. The dimensions of the pallet were 109-cm wide by 132-cm long by 123-cm tall,...

  3. AcEST: BP915657 [AcEST

    Full Text Available Aspartate-semialdehyde dehydrogenase OS=Met... 31 3.1 sp|O15164|TIF1A_HUMAN Transcription intermediary fact...YKDACYWFQDRDIPENIKDMVVIPTDPKHEEFEDVDIVFSALPSDLA 96 Query: 227 R 229 + Sbjct: 97 K 97 >sp|O15164|TIF1A_HUMAN Transcription intermediar

  4. 78 FR 45196 - Federal Acquisition Regulation; Information Collection; Rights in Data and Copyrights

    2013-07-26

    ... surveying the major civilian R&D agencies, whose data suggested that the average value of an R&D contract... subcontracting). Thus, for most R&D contracts with universities, no recordkeeping is required. (3) FAR 52.227-17.... Subject matter experts in the intellectual property law field were consulted to obtain...

  5. Investigating Factors in the Retention of Students in High School Physical Education

    Lodewyk, Ken R.; Pybus, Colin M.

    2013-01-01

    Several studies have reported declining student enrolment rates in optional physical education. This study--incorporating constructs from social cognitive, self-determination, and body image theory--investigated factors that might be influential to this trend. Surveys were administered to 227 tenth-grade students from five schools in one school…

  6. China’s Energy Security and the South China Sea

    2002-05-01

    field of geoeconomics . The cornerstone of interdependence is derived from the notion that economic and technological strength within the modern world...advanced industrial societies (Keohane and Nye 1977, 226-227; Nye 2002, 7-8). Nye concedes that geoeconomics has not replaced geopolitics, but he does point

  7. The French Version of the Modified-Checklist for Autism in Toddlers (M-CHAT): A Validation Study on a French Sample of 24 Month-Old Children

    Baduel, Sophie; Guillon, Quentin; Afzali, Mohammad H.; Foudon, Nadège; Kruck, Jeanne; Rogé, Bernadette

    2017-01-01

    Early ASD screening has the potential to reduce delays between initial parental concerns and diagnosis, and promote early intervention. The aim of this study was to validate the M-CHAT on a French population sample of 24 month-old children. This study included a low-risk sample of 1,227 children. A total of 20 children screened positive on the…

  8. Environmental Early Warning Systems (EEWS): Equation Writer’s Manual.

    1986-07-01

    MNGMTBURDEN% % 0.29 NO DATA *BIG_ IMPACT? FLAG NO NO DATA +ENDANGDAM FLAG NO PROBLEM PROBLEM NOTE NO. 227 BLISS - (New Mexico Section)------ ROC HT POC...topic are defined by the researcher in charge of that area of interest. Usually, a user will see output by requesting to zee the contents of a specific

  9. Rose Atoll Site 29P 7/31/2004 27-28M

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Rose Atoll, site 29P (14 32.227S, 168 09.122W), between 27 and 28 meters along a permanent transect.

  10. Prokinetic Therapy Reduces Aspiration Pneumonia in Tube-Fed Patients With Severe Developmental Disabilities

    Pareek, Namita; Williams, John; Hanna, Deborah; Johnson, William D.; Minocha, Anil; Abell, Thomas L.

    2007-01-01

    To evaluate the clinical benefit of prokinetic therapy in aspiration pneumonia in patients with developmental disabilities, we conducted a retrospective study; records of 22 tube-fed patients were reviewed from December 1990 to October 1998 for a mean of 22.7 months before and 38.9 months during Cisapride therapy. Numbers of hospital admissions…

  11. Evaluation and reselection of wheat resistance to Russian wheat aphid biotype 2

    Russian wheat aphid (RWA, Diuraphis noxia, Mordvilko) biotype 2 (RWA2) is virulent to most known RWA resistance genes and severely threatens wheat production in the hard winter wheat area of the US western Great Plains. We determined RWA2 reactions of 386 cultivars from China, 227 advanced breeding...

  12. Phonological Processing Skills and Early Reading Abilities in Hong Kong Chinese Kindergarteners Learning to Read English as a Second Language

    Chow, Bonnie Wing-Yin; McBride-Chang, Catherine; Burgess, Stephen

    2005-01-01

    The present 9-month longitudinal study investigated relations between Chinese native language phonological processing skills and early Chinese and English reading abilities among 227 kindergarteners in Hong Kong. Phonological awareness, rapid automatized naming, and short-term verbal memory differed in their relations to concurrent and subsequent…

  13. Electronic Attack and Sensor Fusion Techniques for Boost-phase Defense Against Multiple Ballistic Threat Missiles

    2005-06-01

    ferrite, iron, and cobalt -nickel alloys, are used to alter the permeability of the materials. High dielectric materials, such as carbon, graphite...chaff cloud can be found from [19] c kW f σ = (2.2.7) where 217000 m -GHz/lbk = for aluminized glass chaff, which has a density of 2550 3kg m

  14. Prediction of Hydrodynamics for Unidirectional Flow

    2013-09-30

    the Regional Ocean Modeling System, J. Comp. Phys, 227, 3595-3624. Wilson, G., H.T. Ozkan-Haller and R.A. Holman , Data assimilation and bathymetric...R.A. Holman , Data assimilation and bathymetric inversion in 2DH surf zone model, J. Geophys. Res., 115, C12057, doi:10.1029/2010JC006286. Wilson

  15. Examination of Multicultural Counseling Competencies in School Counselors

    Guzman, Michele R.; Calfa, Nicolina A.; Kerne, Valerie Van Horn; McCarthy, Christopher

    2013-01-01

    The study investigated 227 school counselor's multicultural counseling competencies (MCC). MCC were measured with a self-report inventory, and with ratings of responses to short vignettes, designed to assess "demonstrated" competency. Results indicated that school counselor self-ratings did not predict demonstrated ratings of MCC. People…

  16. EST Table: BP124964 [KAIKOcDNA[Archive

    Full Text Available BP124964 fbpv0143 10/09/28 70 %/223 aa ref|NP_001040215.1| stathmin [Bombyx mori] gb|ABD36259.1| stathmin...0/09/10 42 %/227 aa gi|91083957|ref|XP_975021.1| PREDICTED: similar to stathmin [Tribolium castaneum] FS915193 fbpv ...

  17. Gclust Server: 176000 [Gclust Server

    Full Text Available 176000 Ava_Ava_3490 Cluster Sequences - 227 hypothetical protein 1 1.00e-99 0.0 0.0... 4.0 0.0 0.0 0.0 Show 176000 Cluster ID 176000 Sequence ID Ava_Ava_3490 Link to cluster sequences Cluster Se

  18. Phase 1 dose-escalation study of the antiplacental growth factor monoclonal antibody RO5323441 combined with bevacizumab in patients with recurrent glioblastoma

    Lassen, Ulrik; Chinot, Olivier L; McBain, Catherine

    2015-01-01

    , with increases in VEGFA and decreases in FLT4, was observed. Dynamic contrast-enhanced/diffusion-weighted MRI revealed large decreases in vascular parameters that were maintained through the dosing period. Combination therapy achieved an overall response rate of 22.7%, including one complete response, and median...

  19. フルパスタチンは ヒト瞬帯血管肉皮細胞における組織因子インヒビタ一発現を増加させる

    2015-01-01

    博士論文要旨Abstract 以下に掲載:Journal of Atherosclerosis and Thrombosis 22(7) pp.660-668 2015. Japan Atherosclerosis Society. 共著者:Akiko Sekiya, Eriko Morishita, Keiko Maruyama, Hiroki Torishima, Shigeki Ohtake

  20. Numerical Simulation of Gleeble Torsion Testing of HSLA-65 Steel

    2008-04-01

    LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 36 19b. TELEPHONE NUMBER (include area code) 301 -227-5033 Standard Form 298 (Rev. 8-98...3800 Torsion machine on AISI 304L and HSLA-65 steels to simulate the friction stir welding of these materials. A photograph of the experimental setup

  1. Kirjad vallutatud Hiinast / Karl Rumor

    Rumor, Karl, pseud., 1886-1971

    2008-01-01

    1937. a. alanud Hiina-Jaapani sõjast, poliitlistest oludest ja revolutsioonist Hiinas, hiinlastest ja Hiina suhetest teiste riikidega. Varem ilmunud: Uus Eesti 19.-20. aug, 1938, nr. 226-227; 12.-13., 16. sept. 1938, nr. 250-251, 254

  2. EST Table: FS729067 [KAIKOcDNA[Archive

    Full Text Available FS729067 E_FL_bmmt_14P20_F_0 10/09/28 100 %/214 aa ref|NP_001136399.1| kynureninase... [Bombyx mori] dbj|BAH03383.1| kynureninase [Bombyx mori] 10/09/03 n.h 10/08/28 33 %/227 aa C15H9.7#CE06835#WBGene00015802#kynure

  3. Fostering Biliteracy in a Monolingual Milieu: Reflections on Two Counter-Hegemonic English Immersion Classes

    Manyak, Patrick C.

    2006-01-01

    This article presents data from two yearlong ethnographic studies of the biliteracy instruction and development of young Latina/o children in two counter-hegemonic English immersion classes in the English-only milieu established by California's Proposition 227. The author first describes the struggle that the teachers engaged in as they sought to…

  4. National Manpower Inventory. Volume 3. Technical Documentation for Software for the Model

    1985-09-01

    Knitting mills (225) 140 Dyeing and finishing textiles, except >%ool and knit goods (226) 141 Floor coverings, except hard surface (227...occupatbns (5211) 434 Bartenders (5212) 435 Walters and waitresses (5213) 436 Cooks, except short order (5214) 437 Short-order cooks (5215

  5. Superplastic Behavior of Ti-6Al-4V-0.1B Alloy (Preprint)

    2011-10-01

    Galeyev, O.R. Valiakhmetov, F.H. (Sam) Froes, Journal of Alloys and Compounds 345 (2002) 221–227. 8. A.V. Sergueeva, V.V. Stolyarov, R.Z. Valiev... Journal of Alloys and Compounds 490 (2010) 118–123. 7 Approved for public release; distribution unlimited. 17. S. Tamirisakandala, R.B. Bhat

  6. 48 CFR 1827.305-4 - Conveyance of invention rights acquired by the Government. (NASA supplements paragraph (a))

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Conveyance of invention... PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1827.305-4 Conveyance of invention... entire right to, title to, and interest in an invention under the clause at 1852.227-70, New...

  7. 75 FR 22524 - Ocean Dumping; Designation of Ocean Dredged Material Disposal Sites Offshore of the Siuslaw River...

    2010-04-29

    ... AGENCY 40 CFR Part 228 Ocean Dumping; Designation of Ocean Dredged Material Disposal Sites Offshore of... according to the ocean dumping regulations at 40 CFR 227.13 and guidance developed by EPA and the Corps. In... acceptable for ocean dumping without further testing. Dredged material which does not meet the criteria of...

  8. 75 FR 5708 - Ocean Dumping; Designation of Ocean Dredged Material Disposal Sites Offshore of the Siuslaw River...

    2010-02-04

    ... AGENCY 40 CFR Part 228 Ocean Dumping; Designation of Ocean Dredged Material Disposal Sites Offshore of... any person, EPA and the Corps must evaluate the project according to the ocean dumping regulatory criteria (40 CFR part 227) and authorize disposal. EPA independently evaluates proposed dumping and has...

  9. 76 FR 31453 - Special Conditions: Gulfstream Model GVI Airplane; Single-Occupant Side-Facing Seats

    2011-06-01

    ...; facsimile (425) 227-1320. SUPPLEMENTARY INFORMATION: Background On March 29, 2005, Gulfstream Aerospace... issue a finding of regulatory adequacy pursuant to section 611 of Public Law 92-574, the ``Noise Control... processed as defined in Federal Motor Vehicle Safety Standard (FMVSS) part 571.214, section S6.13.5....

  10. THE PERCEPTION OF MUSIC SYMBOLS IN MUSIC READING BY NORMAL CHILDREN AND BY CHILDREN GIFTED MUSICALLY.

    PETZOLD, ROBERT G.

    THIS STUDY WAS CONCERNED WITH IDENTIFYING THE DIFFERENCES BETWEEN CHILDREN OF AVERAGE MUSICAL ABILITY AND CHILDREN GIFTED MUSICALLY AS THEY ENGAGED IN CERTAIN MUSIC ACTIVITIES. DATA WERE OBTAINED FROM TESTS OF 227 MADISON, WISCONSIN, PUBLIC SCHOOL CHILDREN, GRADES 4-6. THE TAPE-RECORDING TEST WAS IN 2 PHASES--(1) 89 CHILDREN, SELECTED AT RANDOM…

  11. How Can We Best Serve LEP Students? A Reply to Nicholas Meier and Stephen Krashen.

    Baker, Keith

    1999-01-01

    Meier and Krashen, both employed in California's education system, do an injustice to students in rehashing an already settled battle. Fed up with two decades of failure, California voters replaced bilingual education with structured English immersion. Meier and Krashen offer no suggestions for coping with Proposition 227. (27 references) (MLH)

  12. Commanders Responsibilities in the Operations Process During the 1864 Red River Expedition

    2015-05-21

    1, vol. 34, part 1, 227. The Battle of Pleasant Hill occurred the following morning, 9 April.37 Union and Confederate forces battled furiously ...much indebted for the happy manner in which he forwarded this enterprise, giving it his whole attention day and night, scarcely sleeping while the work

  13. Commanders’ Responsibilities in the Operations Process During the 1864 Red River Expedition

    2015-05-21

    1, vol. 34, part 1, 227. The Battle of Pleasant Hill occurred the following morning, 9 April.37 Union and Confederate forces battled furiously ...much indebted for the happy manner in which he forwarded this enterprise, giving it his whole attention day and night, scarcely sleeping while the work

  14. The Crimean Tatars and Their Influence on the `Triangle of Conflict’ - Russia-Crimea-Ukraine

    2008-03-01

    inhabitants, who were mentioned in literary references, were “the Cimmerians. Homer, in the Odyssey, mentioned them as the ones who populated the...47 Charles J. Halperin, Russia and the Golden Horde: the Mongol Impact on Medieval Russian History...extent and subject to distortion in light of contemporary political goals and issues.226 Moreover, Crimea is the multiethnic literary landscape,227 and

  15. Cross-Ethnic Friendships and Sense of Social-Emotional Safety in a Multiethnic Middle School: An Exploratory Study

    Munniksma, Anke; Juvonen, Jaana

    2012-01-01

    This exploratory study examined whether cross-ethnic friendships are related to students' sense of social-emotional safety in a multiethnic middle school. The analysis sample (n = 227) consisted of Latino (57%) and White (43%) sixth- and seventh-grade students. Although a strong preference for same-ethnic friendships was found for both ethnic…

  16. Cross-ethnic friendships and sense of social-emotional safety in multi-ethnic middle school: An exploratory study

    Munniksma, A.; Juvonen, J.

    2012-01-01

    This exploratory study examined whether cross-ethnic friendships are related to students’ sense of social-emotional safety in a multiethnic middle school. The analysis sample (n = 227) consisted of Latino (57%) and White (43%) sixth- and seventh-grade students. Although a strong preference for same-

  17. The Consistency of Attitude and Behavior by Adolescents in the Area of Energy Conservation.

    Lytle, Jacque R.; Chamberlain, Valerie M.

    This study examined the relationship between the energy use for personal and family activities. Data were collected from a sample of 227 students in 11 secondary public schools in central city, suburban, small town, and rural areas. Students completed instruments that measured energy conservation attitudes, behaviors, and levels of attitudinal…

  18. 47 CFR 95.629 - LPRS transmitter frequencies.

    2010-10-01

    ....629 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES Technical Regulations Technical Standards § 95.629 LPRS transmitter frequencies. (a....8075 223 216.8125 224 216.8175 225 216.8225 226 216.8275 227 216.8325 228 216.8375 229 216.8425 230...

  19. 47 CFR 90.613 - Frequencies available.

    2010-10-01

    ... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Regulations Governing Licensing and Use of Frequencies in the 806-824, 851-869, 896... 221 .8750 222 .8875 223 .9000 224 .9125 225 .9250 226 .9375 227 .9500 228 .9625 229 .9750 230...

  20. Dicty_cDB: CHG384 [Dicty_cDB

    Full Text Available 2 3e-36 AF268611_12( AF268611 |pid:none) Uncultured marine group II euryar... 34 1.6 D43959_1( D43959 |pid:none) Thiobacillus thiooxi...dans plasmid pTTY1... 33 4.7 CR382125_227( CR382125 |pid:none) Kluyveromyces lactis

  1. Beyond Good Intentions: The effectiveness of a proactive self-management intervention in patients with screen-detected type 2 diabetes

    Thoolen, B.J.

    2007-01-01

    This prospective randomized controlled trial evaluated a theory-driven group-based self-management course for patients with screen-detected type 2 diabetes. 227 patients receiving either intensive pharmacological or usual-care treatment since diagnosis (3-33 months previously) agreed to participate

  2. Development of Advanced Technologies for Complete Genomic and Proteomic Characterization of Quantized Human Tumor Cells

    2014-07-01

    four parental cell lines and eleven subclones derived (Figure 11). We have begun deep proteome analysis of the secretomes by performing off- gel ...1 Antihelminthic 33 7 7 Antiarrhythmic 24 0 1 Antibacterial 227 11 11 Antifungal 55 5 5 Antineoplastic 115 29 28 Antihyperlipidemic 12 3 4

  3. Cross-ethnic Friendships and Sense of Social-Emotional Safety in a Multiethnic Middle School : An Exploratory Study

    Munniksma, Anke; Juvonen, Jaana

    2012-01-01

    This exploratory study examined whether cross-ethnic friendships are related to students' sense of social-emotional safety in a multiethnic middle school. The analysis sample (n = 227) consisted of Latino (57%) and White (43%) sixth-and seventh-grade students. Although a strong preference for same-e

  4. Drug: D01333 [KEGG MEDICUS

    Full Text Available D01333 Drug Urapidil (JP16/INN); Ebrantil (TN) C20H29N5O3 387.227 387.476 D01333.gif Antihypertensive...vascular agents 214 Antihypertensives 2149 Others D01333 Urapidil (JP16/INN) 25 U...tagonists Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardio

  5. File list: ALL.Myo.20.AllAg.Myotube [Chip-atlas[Archive

    Full Text Available ALL.Myo.20.AllAg.Myotube mm9 All antigens Muscle Myotube SRX497486,SRX497487,SRX227...232,SRX497488,SRX236484,SRX497489,SRX227230 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.20.AllAg.Myotube.bed ...

  6. File list: ALL.Myo.10.AllAg.Myotube [Chip-atlas[Archive

    Full Text Available ALL.Myo.10.AllAg.Myotube mm9 All antigens Muscle Myotube SRX497486,SRX497487,SRX227...232,SRX497488,SRX236484,SRX227230,SRX497489 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/ALL.Myo.10.AllAg.Myotube.bed ...

  7. ATOMIC DATA FOR ABSORPTION-LINES FROM THE GROUND-LEVEL AT WAVELENGTHS GREATER-THAN-228-ANGSTROM

    VERNER, DA; BARTHEL, PD; TYTLER, D

    1994-01-01

    We list wavelengths, statistical weigths and oscillator strengths for 2249 spectral lines arising from the ground states of atoms and ions. The compilation covers all wavelengths longward of the HeII Lyman limit at 227.838 Angstrom and all the ion states of all elements from hydrogen to bismuth (Z =

  8. Domain Modeling: NP_113674.1 [SAHG[Archive

    Full Text Available NP_113674.1 chr9 CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA c1meyf_ chr9/NP_113674....1/NP_113674.1_holo_94-171.pdb psi-blast 225C,227Q,228C,229G,230K,231P,232L,233H,234H,2

  9. Martin Creed: "Tahan luua keskkonna, kus on hea olla" / intervjueerinud Maria Arusoo

    Creed, Martin, 1968-

    2011-01-01

    Tallinna Kunstihoones 29. sept.-l publikuga kohtunud inglise kunstnik, muusik ja teoreetik Martin Creed endast, oma loomingust, loomeprotsessist, oma Turner Prize'i pälvinud installatsioonist "Work No 227. Lights going on and off", mis oli väljas näitusel "Continuum_Kunst kui taju. Ruum kui protsess" jm.

  10. 45 CFR 170.299 - Incorporation by reference.

    2010-10-01

    ... CFR part 51. To enforce any edition other than that specified in this section, the Department of... available from the sources listed below. (b) Health Level Seven, 3300 Washtenaw Avenue, Suite 227, Ann Arbor....5 Message Structure Specification for National Condition Reporting Final Version 1.0,...

  11. Impaired parent-reported health-related quality of life of underweight and obese children at elementary school entry

    A. van Grieken (Amy); L. Veldhuis (Lydian); C.M. Renders (Carry); J.M. Landgraf (Jeanne); R.A. Hirasing (Remy); H. Raat (Hein)

    2013-01-01

    textabstractPurpose Examine the health-related quality of life of 5-6-year-old underweight, overweight and obese children. Methods Our cross-sectional study included 3,227 parent- child dyads from the "Be active, eat right" study. Parents completed questionnaires regarding child and parental charact

  12. A comparison between composition and density of the fat-free mass of young adult Singaporean Chinese and Dutch Caucasians

    Werkman, A.; Deurenberg-Yap, M.; Schmidt, G.; Deurenberg, P.

    2000-01-01

    The body composition was measured in 30 female Singapore Chinese and 34 female Dutch Caucasians aged (mean ± SD) 22.7 ± 3.6 years and in 39 male Singapore Chinese and 39 male Dutch Caucasians aged 23.3 ± 3.2 years. Methods: The body fat percentage (BF€was measured using densitometry and deuterium ox

  13. Attitudes towards Technical Drawing as a School Subject.

    Chinzvimbo, George

    A case study was conducted of attitudes toward technical drawing and the present state of technical drawing in Zimbabwe. The study involved two high schools. In one school, 227 students (85 percent of the total) responded to questionnaires; in the other, the response was 84 students (70 percent). Eleven teachers were also surveyed. The study…

  14. 78 FR 62660 - Outer Continental Shelf (OCS), Gulf of Mexico (GOM), Oil and Gas Lease Sales Eastern Planning...

    2013-10-22

    ... Lease Sales 227, 231, 235, 241, and 247, Final Environmental Impact Statement (2012-2017 WPA/CPA... Statement (WPA 233/CPA 231 Supplemental EIS; OCS EIS/EA BOEM 2013-0118). The Final EIS also tiers from the... and will be distributing a limited number of paper copies. In keeping with the Department of...

  15. Quantitative Uncertainty Assessment and Numerical Simulation of Micro-Fluid Systems

    2005-04-01

    deployment strategies can be formulated. It is also essential to conduct such analyses during the design stages, so as to avoid or minimize costly field...1991). 10. G. De Vahl Davis and I. P. Jones, Natural convection in a square cavity: A comparison exercice , Int. J. Numer. Methods Fluids 3, 227

  16. Antibacterial activity of marine-derived fungi

    Christophersen, Carsten; Crescente, Oscar; Frisvad, Jens Christian

    1998-01-01

    A total of 227 marine isolates of ubiqituous fungi were cultivated on different media and the secondary metabolite content of the extracts (ethyl acetate/chlorofonn/methanol 3 : 2 : 1) characterized by HPLC. The fungi were secured from animals, plants and sediments of Venezuelan waters (0-10 m...

  17. Breeding of an anti-postacidification strain from Lactobacillus bulgaricus by NTG mutagenesis%抗后酸化保加利亚乳杆菌的亚硝基胍诱变选育

    车黎猛; 任发政; 张恒涛; 常征; 蔡华伟

    2006-01-01

    利用0.9mg/mL亚硝基胍对保加利亚乳杆菌ZLB进行诱变处理30min(菌株致死率为99%),中间培养后用青霉素筛选.处理液涂布培养后,选取生长缓慢或不长的32株接种于RSM(Reconstituted Skimmed Milk)培养基中,随后选取凝固的16株做12℃贮藏,最终得到产酸较慢的突变株ZT224、ZT227.突变株与ZLB相比,在42℃时,ZT224、ZT227在RSM培养基中滴定酸度值明显减少.发酵脱脂乳在12℃贮藏时,ZT224的发酵乳在贮藏的20d内一直没有发生后酸化;ZT227发生后酸化的时间推迟了4d.同时,突变株ZT224、ZT227对链霉素的敏感性不同于出发菌株ZLB且能稳定遗传.

  18. Theoretical Advanced Study Institute: 2014

    DeGrand, Thomas [Univ. of Colorado, Boulder, CO (United States)

    2016-08-17

    The Theoretical Advanced Study Institute was held at the University of Colorado, Boulder, during June 2-27, 2014. The topic was "Journeys through the Precision Frontier: Amplitudes for Colliders." The organizers were Professors Lance Dixon (SLAC) and Frank Petriello (Northwestern and Argonne). There were fifty one students. Nineteen lecturers gave sixty seventy five minute lectures. A Proceedings was published.

  19. EST Table: DY231350 [KAIKOcDNA[Archive

    Full Text Available DY231350 EST02101 10/09/28 99 %/227 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori

  20. EST Table: DN237644 [KAIKOcDNA[Archive

    Full Text Available DN237644 EST00770 10/09/29 99 %/227 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori

  1. EST Table: DN237680 [KAIKOcDNA[Archive

    Full Text Available DN237680 EST00806 10/09/29 95 %/227 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori

  2. A Framework to Support Automated Classification and Labeling of Brain Electromagnetic Patterns

    2007-10-01

    Spatial analysis of evoked po- tentials in man—a review,” Progress in Neurobiology, vol. 23, no. 3, pp. 227–250, 1984. [38] “ Cartool software...Functional Brain Mapping Laboratory, Geneva, Switzerland, http://brainmapping.unige.ch/ Cartool .htm. [39] T. Koenig, K. Kochi, and D. Lehmann, “Event

  3. The birth of counterjihadist terrorism: reflections on some unspoken dimensions of 22 July 2011

    Asprem, E.

    2011-01-01

    The religious and ideological standpoints of the Norwegian terrorist Anders Behring Breivik gathered some attention by scholars of religious studies in the wake of the 22/7 attacks in Oslo and on Utøya. These comments mostly focused on the question of Breivik's alleged Christianity: in what sense is

  4. Quality of life among prostate cancer patients : A prospective longitudinal population-based study

    Schaake, Wouter; de Groot, Martijn; Krijnen, Wim P.; Langendijk, Johannes A.; van den Bergh, Alfons C. M.

    2013-01-01

    Purpose: To investigate the course of quality of life (QoL) among prostate cancer patients treated with external beam radiotherapy and to compare the results with QoL of a normal age-matched reference population. Patients and methods: The study population was composed of 227 prostate cancer patients

  5. The impact of gastrointestinal and genitourinary toxicity on health related quality of life among irradiated prostate cancer patients

    Schaake, Wouter; Wiegman, Erwin M; de Groot, Martijn; van der Laan, Hans Paul; van der Schans, Cees P.; van den Bergh, Alfons C M; Langendijk, Johannes A

    2014-01-01

    PURPOSE: To determine the impact of late radiation-induced toxicity on health-related quality of life (HRQoL) among patients with prostate cancer. PATIENTS AND METHODS: The study sample was composed of 227 patients, treated with external beam radiotherapy. Common Terminology Criteria for Adverse Eve

  6. 75 FR 7657 - Truth in Lending

    2010-02-22

    ... System 12 CFR Parts 226 and 227 Truth in Lending; Unfair or Deceptive Acts or Practices; Final Rules #0...; ] FEDERAL RESERVE SYSTEM 12 CFR Part 226 Truth in Lending AGENCY: Board of Governors of the Federal Reserve System. ACTION: Final rule. SUMMARY: The Board is amending Regulation Z, which implements the Truth...

  7. Reconstruction of depositional environment of a tropical estuary and response of δ 13 Corg and TOC/TN signatures to changing environmental conditions

    Volvoikar, S.P.; Nayak, G.N.; Mazumdar, A.; Peketi, A.

    of Maharashtra. Gonneea, M. E., Paytan, A., Herrera-Silveira, J. A., 2004. Tracing organic matter sources and carbon burial in mangrove sediments over the past 160 years. Estuarine, Coastal and Shelf Science 61, 211-227. Hu, J., Peng, P., Jia, G., Mai, B...

  8. United States Security Interests in China: Beyond the ’China Card’.

    1981-09-01

    Joseph Frederick Bouchard 9. PERFORMINGO ORGANOIZATION NAME AND AOORESS 10. PROGRAM ELEMET PROJECT, TASKAREA * WORK UNI"T NUM~Eans Naval Postgraduate...reverse. Asia is geographic shorthand for a diverse collec- tion of cultures, societies and politico -economic 227 .. .. .. . . I | III -- L I

  9. MARKET WATCH

    HU YUE

    2011-01-01

    Economic Figures Foreign trade In the first three quarters of 2011,China's exports totaled $1.39 trillion,growing 22.7 percent year on year,while imports climbed 26.7 percent to reach $1.29 trillion,according to data from the General Administration of Customs (GAC).The trade surplus stood at $107.1 billion.

  10. Data of evolutionary structure change: 1XICA-4XIMD [Confc[Archive

    Full Text Available 1XICA-4XIMD 1XIC 4XIM A D YQPTPEDRFTFGLWTVGWQGRDPFGDATRRALDPVESVQ...Y CA 227 TYR CA 313 SER CA 291 GLY CA 397 4X...IM D 4XIMD DLLENG...07 GLN CA 106 ALA CA 123 4XIM D 4XIMD TPTLNPGEGYAE

  11. [Three new observational scales for use in Dutch nursing homes: scales from the Resident Assessment Instrument for Activities of Daily Living, cognition and depression

    Gerritsen, D.; Ooms, M; Steverink, N.; Frijters, D.; Bezemer, D.; Ribbe, M

    2004-01-01

    The reliability and validity of three MDS scales for ADL, cognition and depression are described. The scales consist of items of the Minimum Data Set of the Resident Assessment Instrument and are available just after an MDS assessment. Data collection took place in nine Dutch nursing homes (N = 227)

  12. Broadband Teleseismic Array Recording in the Adirondack Mountains, New York State

    1993-04-30

    to the surrounding terrain. The exposed Adirondack granulite is believed to represent a small window of the much larger Grenville Province in Ontario...on experimental studies of seismic velocities in granulite , Geological Society of America Bulletin, v. 86, 227-236. Connery, J.E.P., and A.F. Kuckes

  13. 77 FR 68196 - Orders Limiting Operations at John F. Kennedy International Airport, LaGuardia Airport, and...

    2012-11-15

    ... CFR 93.227 (DCA); 74 FR 51648 (Oct. 7, 2009) (EWR); 74 FR 51650 (Oct. 7, 2009) (JFK); 77 FR 30585 (May... Authorizations (slots) at John F. Kennedy International Airport (JFK), LaGuardia Airport (LGA), and Newark... occurred at slot-controlled and non- slot-controlled airports. JFK and EWR were effectively closed...

  14. It's All Relative: Different Levels of Relational Similarity Used in Children's Comparisons

    Paik, Jae H.; Mix, Kelly S.

    2008-01-01

    Using a sticker search task, Gentner and Rattermann ("Perspectives on thought and language: Interrelations in development" (Gelman & Byrnes, Eds.), pp. 225-227, 1991) found that the ability to ignore surface features and match objects in terms of relative size emerged around 5 years of age. However, because spatial position covaried with relative…

  15. Falconry

    1990-06-01

    Leadore, Idaho: Western Ecological Studies Team, 1989. (In process) 62. Gaskin, Catherine. A falcon for a queen . Garden City, N.Y: Doubleday, 1972. [1st...Richard D. "DDE thins eggshells of captive American kestrels." Nature. 227: 737-38, 15 August 1970. 549. Williamson, Henry. "The backbreakers bride

  16. 78 FR 40402 - Radio Broadcasting Services; Roaring Springs, Texas

    2013-07-05

    ... COMMISSION 47 CFR Part 73 Radio Broadcasting Services; Roaring Springs, Texas AGENCY: Federal Communications... Channel 227A and deletes FM Channel 249A at Roaring Springs, Texas, and allots FM Channel 249C3 and deletes FM Channel 276C3 at Roaring Springs. These allotment changes are part of a rule making and...

  17. Distributing and Showing Farmer Learning Videos in Bangladesh

    Bentley, Jeffery W.; Van Mele, Paul; Harun-ar-Rashid, Md.; Krupnik, Timothy J.

    2016-01-01

    Purpose: To describe the results of showing farmer learning videos through different types of volunteers. Design/Methodology/Approach: Semi-structured interviews with volunteers from different occupational groups in Bangladesh, and a phone survey with 227 respondents. Findings: Each occupational group acted differently. Shop keepers, tillage…

  18. 75 FR 9017 - Orders Limiting Scheduled Operations at John F. Kennedy International Airport, LaGuardia Airport...

    2010-02-26

    ... CFR Sec. 93.227 (DCA); 74 FR 51648 (Oct. 7, 2009) (EWR); 74 FR 51650 (Oct. 7, 2009) (JFK); 74 FR 51653... Airport, LaGuardia Airport and Newark Liberty International Airport; High Density Rule at Reagan National Airport AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of limited waiver of the...

  19. 76 FR 19517 - Orders Limiting Scheduled Operations at John F. Kennedy International Airport, LaGuardia Airport...

    2011-04-07

    ....\\1\\ \\1\\ 75 FR 9017 (Feb. 26, 2010). ATA also stated the National Oceanic and Atmospheric...\\ 14 CFR 93.227 (DCA); 74 FR 51648 (Oct. 7, 2009) (EWR); 74 FR 51650 (Oct. 7, 2009) (JFK); 74 FR 51653... Airport, LaGuardia Airport, and Newark Liberty International Airport; High Density Rule at Reagan...

  20. 糙皮侧耳和康氏木霉二步混合发酵生产饲料蛋白的研究%STUDY ON FORAGE PROTEIN PRODUCTION BY TWO-STEP MIXED CULTURE FERMENTATION WITH Pleurotus ostreatus AND Trichoderma koningii

    陈敏

    2002-01-01

    研究了糙皮侧耳(Pleurotus ostreatus)和康氏木霉C-3(Trichoderma Koningii C-3)降解稻草生产饲料蛋白的发酵工艺.发酵产物的粗蛋白含量达到 22.7 %,粗纤维降解率为 34 %.