WorldWideScience

Sample records for actinium 219

  1. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-08-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1- ligands (3.2+/-1.1) than AmIII (0.8+/-0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour.

  2. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac–Cl and Ac–OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1– ligands (3.2±1.1) than AmIII (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour. PMID:27531582

  3. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  4. Production of high-purity radium-223 from legacy actinium-beryllium neutron sources.

    Science.gov (United States)

    Soderquist, Chuck Z; McNamara, Bruce K; Fisher, Darrell R

    2012-07-01

    Radium-223 is a short-lived alpha-particle-emitting radionuclide with potential applications in cancer treatment. Research to develop new radiopharmaceuticals employing (223)Ra has been hindered by poor availability due to the small quantities of parent actinium-227 available world-wide. The purpose of this study was to develop innovative and cost-effective methods to obtain high-purity (223)Ra from (227)Ac. We obtained (227)Ac from two surplus actinium-beryllium neutron generators. We retrieved the actinium/beryllium buttons from the sources and dissolved them in a sulfuric-nitric acid solution. A crude actinium solid was recovered from the solution by coprecipitation with thorium fluoride, leaving beryllium in solution. The crude actinium was purified to provide about 40 milligrams of actinium nitrate using anion exchange in methanol-water-nitric acid solution. The purified actinium was then used to generate high-purity (223)Ra. We extracted (223)Ra using anion exchange in a methanol-water-nitric acid solution. After the radium was separated, actinium and thorium were then eluted from the column and dried for interim storage. This single-pass separation produces high purity, carrier-free (223)Ra product, and does not disturb the (227)Ac/(227)Th equilibrium. A high purity, carrier-free (227)Th was also obtained from the actinium using a similar anion exchange in nitric acid. These methods enable efficient production of (223)Ra for research and new alpha-emitter radiopharmaceutical development.

  5. 219-S chemical compatibility

    Energy Technology Data Exchange (ETDEWEB)

    GOODWIN, L.D.

    1999-08-31

    This document consists of tables of the materials that make up the ''wetted'' parts of the 219-S waste handling facility and a combination of manufacturer lists of chemicals that are not recommended.

  6. Relativistic small-core pseudopotentials for actinium, thorium, and protactinium.

    Science.gov (United States)

    Weigand, Anna; Cao, Xiaoyan; Hangele, Tim; Dolg, Michael

    2014-04-03

    Small-core pseudopotentials for actinium, thorium, and protactinium have been energy-adjusted to multiconfiguration Dirac-Hartree-Fock reference data based on the Dirac-Coulomb-Breit Hamiltonian and the Fermi nucleus model. Corresponding optimized valence basis sets of polarized valence quadruple-ζ quality are presented. Atomic test calculations for the first four ionization potentials show satisfactory results at both the Hartree-Fock and the multireference averaged coupled-pair functional level. Highly correlated Fock-space coupled cluster calculations demonstrate that the new pseudopotentials yield ionization potentials, which are in excellent agreement with corresponding all-electron results and experimental data. The pseudopotentials and basis sets supplement a similar set previously published for uranium.

  7. Effects of spin-orbit coupling on actinium under pressure

    Energy Technology Data Exchange (ETDEWEB)

    Rubio-Ponce, A.; Rivera, J. [Departamento de Ciencias Basicas, Universidad Autonoma Metropolitana-Azcapotzalco, Mexico (Mexico); Olguin, D. [Departamento de Fi sica, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico (Mexico)

    2015-04-15

    Actinium (Ac) is a radioactive metal and the first element of the actinide series. At ambient conditions Ac crystallizes in the fcc lattice, however, up to date its phase diagram is unknown. In the present work, we have studied the structural and electronic properties of Ac under hydrostatic pressure assuming the fcc structure as well as three hypothetical structures, namely the hcp, bcc, and sc, and for pressures up to 100 GPa. From our calculations, we found only one structural transition allowed, from the fcc to hcp, our calculated pressure was 39.85 GPa. The calculations were performed by means of the full potential linearized augmented plane wave (FLAPW) method and the generalized gradient approximation (GGA) for the exchange-correlation energy, where we have included in our study the spin-orbit coupling which is important for heavy elements. The total energy results were fitted to the third order Birch-Murnaghan's equation of state. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  9. Comment: 219 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Japanese medaka Oryzias latipes Oryzias_latipes_L.png 219.png Taxonomy icon (c) Database Center for Life Sci...ence licensed under CC Attribution2.1 Japan アイコン:メダカ HNI-Ⅱ系統バージョン bando 2010/02/15 15:31:07 2010/02/16 09:53:27 ...

  10. Report for General Research September 18 to December 11, 1950 (Actinium Volume)

    Energy Technology Data Exchange (ETDEWEB)

    Haring, M.M.

    1951-01-15

    The purpose of the research work presented in this volume is to develop a process for the separation and purification of actinium-227 produced by neutron bombardment of radium-226 and to develop methods by which uniform films of actinium metal may be deposited on metallic surfaces. The design work on the cave structure and mechanical equipment used in the actinium separation is proceeding on schedule. As the mechanical design phase is nearing completion the emphasis is being directed toward processing equipment. The process as well as the mechanical equipment has been adapted from the research work of F. T. Hagemann and the Remote Control Group at Argonne National Laboratory. Consequently, one of the first objectives is to become familiary with the chemistry of the process and the operation of the mechanical equipment. Cold runs have been made on the T.T.A. benzene extraction using lanthanum and barium in place of actinium and radium. No difficulty with the operation was observed. The formation of precipitates was one of the difficulties encountered with the process as the precipitates carry radium. It has been found that metals such as nickel cause these precipitates to form and should, therefore, be avoided in the construction of equipment. it was also found that a T.T.A. solution exposed to 0.5 curie of polonium over a period of days develops a precipitate. Some new mechanical features hav eshown promise. The use of copper-coated glassware which will hold together even though the glass is cracked has made it possible to replace custom-built heaters with standard heating mantles. A new graphite, silicone grease mixture appears to hold up in stopcocks handling benzene and, as a result, may eliminate the necessary of entering the cave for regreasing. Tests on the preparation of dense concrete have given results which meet the shielding requirements for the cave. A strippable paint and tape combination has been studied and specified to provide for decontamination of

  11. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    Energy Technology Data Exchange (ETDEWEB)

    Momeni, M.H.

    1981-09-01

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore.

  12. 45 CFR 150.219 - Final determination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Final determination. 150.219 Section 150.219... Are Failing To Substantially Enforce HIPAA Requirements § 150.219 Final determination. If, after... the State a written notice of its final determination. The notice includes the following: (a...

  13. 36 CFR 219.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Purpose. 219.1 Section 219.1 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Purpose and Principles § 219.1 Purpose. (a) Land...

  14. 22 CFR 219.160 - Communications.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Communications. 219.160 Section 219.160 Foreign... DEVELOPMENT § 219.160 Communications. (a) The agency shall take appropriate steps to ensure effective communication with applicants, participants, personnel of other Federal entities, and members of the public....

  15. 12 CFR 741.219 - Investment requirements.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Investment requirements. 741.219 Section 741.219 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS... Unions That Also Apply to Federally Insured State-Chartered Credit Unions § 741.219...

  16. 32 CFR 219.114 - Cooperative research.

    Science.gov (United States)

    2010-07-01

    ... cooperative research projects, each institution is responsible for safeguarding the rights and welfare of... 32 National Defense 2 2010-07-01 2010-07-01 false Cooperative research. 219.114 Section 219.114...) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.114 Cooperative research. Cooperative research projects...

  17. 12 CFR 219.24 - Retention period.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Retention period. 219.24 Section 219.24 Banks...) Recordkeeping and Reporting Requirements for Funds Transfers and Transmittals of Funds § 219.24 Retention period. All records that are required to be retained by this subpart shall be retained for a period of five...

  18. 33 CFR 136.219 - Authorized claimants.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorized claimants. 136.219 Section 136.219 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.219...

  19. 36 CFR 219.3 - Overview.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Overview. 219.3 Section 219.3 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.3 Overview. (a)...

  20. 49 CFR 219.17 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Construction. 219.17 Section 219.17 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE General § 219.17 Construction. Nothing in this part— (a)...

  1. Application of ion exchange and extraction chromatography to the separation of actinium from proton-irradiated thorium metal for analytical purposes.

    Science.gov (United States)

    Radchenko, V; Engle, J W; Wilson, J J; Maassen, J R; Nortier, F M; Taylor, W A; Birnbaum, E R; Hudston, L A; John, K D; Fassbender, M E

    2015-02-06

    Actinium-225 (t1/2=9.92d) is an α-emitting radionuclide with nuclear properties well-suited for use in targeted alpha therapy (TAT), a powerful treatment method for malignant tumors. Actinium-225 can also be utilized as a generator for (213)Bi (t1/2 45.6 min), which is another valuable candidate for TAT. Actinium-225 can be produced via proton irradiation of thorium metal; however, long-lived (227)Ac (t1/2=21.8a, 99% β(-), 1% α) is co-produced during this process and will impact the quality of the final product. Thus, accurate assays are needed to determine the (225)Ac/(227)Ac ratio, which is dependent on beam energy, irradiation time and target design. Accurate actinium assays, in turn, require efficient separation of actinium isotopes from both the Th matrix and highly radioactive activation by-products, especially radiolanthanides formed from proton-induced fission. In this study, we introduce a novel, selective chromatographic technique for the recovery and purification of actinium isotopes from irradiated Th matrices. A two-step sequence of cation exchange and extraction chromatography was implemented. Radiolanthanides were quantitatively removed from Ac, and no non-Ac radionuclidic impurities were detected in the final Ac fraction. An (225)Ac spike added prior to separation was recovered at ≥ 98%, and Ac decontamination from Th was found to be ≥ 10(6). The purified actinium fraction allowed for highly accurate (227)Ac determination at analytical scales, i.e., at (227)Ac activities of 1-100 kBq (27 nCi to 2.7 μCi). Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Dicty_cDB: SHF219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SH (Link to library) SHF219 (Link to dictyBase) - - - Contig-U16427-1 SHF219P (Link to Original site) SHF...219F 637 SHF219Z 720 SHF219P 1337 - - Show SHF219 Library SH (Link to library) Clone ID SHF...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SH/SHF2-A/SHF219Q.Seq.d/ Representative seq. ID SHF...219P (Link to Original site) Representative DNA sequence >SHF219 (SHF219Q) /CSM/SH/SHF2-A/SHF...skipntisncyvi**sfv*qtqtvllsskillsslnhfvlxs*xk*mkpllnnks nvmknvfvqlyvlslpslefqivivslnlknllkiqfvqlh*llnliqfytk

  3. Dicty_cDB: SLC219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLC219 (Link to dictyBase) - - - Contig-U16455-1 SLC219Z (Link... to Original site) - - SLC219Z 708 - - - - Show SLC219 Library SL (Link to library) Clone ID SLC219 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC2-A/SLC219Q.Seq.d/ Representative seq. ID SLC21...9Z (Link to Original site) Representative DNA sequence >SLC219 (SLC219Q) /CSM/SL/SLC2-A/SLC219Q.Seq.d/ XXXXX...hqkrnk*iiflnk*hfiiilkkk Frame B: ---itrclqdrwyrycssrscrnwyh*trygrhlcpswsln*sqisrnasrttprspsr* qcrfqr*krfsqrn

  4. 36 CFR 219.30 - Plan documentation.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Plan documentation. 219.30... National Forest System Land and Resource Management Planning Planning Documentation § 219.30 Plan documentation. A plan is a repository of documents that integrates and displays the desired...

  5. 48 CFR 219.7103-1 - General.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false General. 219.7103-1 Section 219.7103-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program...

  6. 48 CFR 219.7103 - Procedures.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Procedures. 219.7103 Section 219.7103 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program...

  7. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

    Science.gov (United States)

    Henriksen, Gjermund; Bruland, Oyvind S; Larsen, Roy H

    2004-01-01

    The present study explores the use of alpha-particle-emitting, bone-seeking agents as candidates for targeted radiotherapy. Actinium and thorium 1,4,7,10 tetraazacyclododecane N,N',N'',N''' 1,4,7,10-tetra(methylene) phosphonic acid (DOTMP) and thorium-diethylene triamine N,N',N'' penta(methylene) phosphonic acid (DTMP) were prepared and their biodistribution evaluated in conventional Balb/C mice at four hours after injection. All three bone-seeking agents showed a high uptake in bone and a low uptake in soft tissues. Among the soft tissue organs, only kidney had a relatively high uptake. The femur/kidney ratios for 227Th-DTMP, 228-Ac-DOTMP and 227Th-DOTMP were 14.2, 7.6 and 6.0, respectively. A higher liver uptake of 228Ac-DOTMP was seen than for 227Th-DTMP and 227Th-DOTMP. This suggests that some demetallation of the 228Ac-DOTMP complex had occurred. The results indicate that 225Ac-DOTMP, 227Th-DOTMP and 227Th-DTMP have promising properties as potential therapeutic bone-seeking agents.

  8. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Energy Technology Data Exchange (ETDEWEB)

    Raeder, S., E-mail: s.raeder@gsi.de [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Bastin, B. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Block, M. [Helmholtz-Institut Mainz, 55128 Mainz (Germany); GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstraße 1, 64291 Darmstadt (Germany); Institut für Kernchemie, Johannes Gutenberg Universität, 55128 Mainz (Germany); Creemers, P. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Delahaye, P. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); Ferrer, R. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fléchard, X. [LPC Caen, ENSICAEN, Université de Caen, CNRS/IN2P3, Caen (France); Franchoo, S. [Institute de Physique Nucléaire (IPN) d’Orsay, 91406 Orsay, Cedex (France); Ghys, L. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); SCK-CEN, Belgian Nuclear Research Center, Boeretang 200, 2400 Mol (Belgium); Gaffney, L.P.; Granados, C. [KU Leuven, Instituut voor Kern- en Stralingsfysica, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Heinke, R. [Institut für Physik, Johannes Gutenberg Universität, 55128 Mainz (Germany); Hijazi, L. [GANIL, CEA/DSM-CNRS/IN2P3, B.P. 55027, 14076 Caen (France); and others

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  9. 48 CFR 219.7106 - Performance reviews.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7106... mentor-protege agreements as indicated in appendix I, section I-113. The determinations made in...

  10. 48 CFR 219.7100 - Scope.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7100 Scope. This... protege firms in enhancing their capabilities and to increase participation of such firms in...

  11. 48 CFR 219.7105 - Reporting.

    Science.gov (United States)

    2010-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7105 Reporting. Mentor and protege firms must report on the progress made under mentor-protege agreements...

  12. 36 CFR 219.10 - Site-specific decisions.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.10... consistent with §§ 219.12 through 219.18, follow the planning framework described in §§ 219.4 through...

  13. Dicty_cDB: CHR219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR219 (Link to dictyBase) - - - Contig-U16511-1 CHR219P (Link to Original site) CHR...219F 609 CHR219Z 786 CHR219P 1375 - - Show CHR219 Library CH (Link to library) Clone ID CHR...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHR2-A/CHR219Q.Seq.d/ Representative seq. ID CHR...219P (Link to Original site) Representative DNA sequence >CHR219 (CHR219Q) /CSM/CH/CHR2-A/CHR...ky**firs*ywswfkw**srrc*kprfirqircf*tsigsrrn*kprfgrscf*nhf*ir trsyssn*wsts*lyc*srnscss*inr*kcl*cllkhrtnittitt

  14. Dicty_cDB: SFI219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFI219 (Link to dictyBase) - - - Contig-U13190-1 SFI219P (Link to Original site) SF...I219F 585 SFI219Z 699 SFI219P 1274 - - Show SFI219 Library SF (Link to library) Clone ID SF...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SF/SFI2-A/SFI219Q.Seq.d/ Representative seq. ID SF...I219P (Link to Original site) Representative DNA sequence >SFI219 (SFI219Q) /CSM/SF/SFI2-A/SFI...AGTAATAATTANNAAAAAAAA sequence update 2001.11.22 Translated Amino Acid sequence cwptgnffif*FINNQNFKYFNYFVFVFNTHKMDSF

  15. 49 CFR 571.219 - Standard No. 219; Windshield zone intrusion.

    Science.gov (United States)

    2010-10-01

    ... Federal Motor Vehicle Safety Standards § 571.219 Standard No. 219; Windshield zone intrusion. S1. Scope.... S3. Application. This standard applies to passenger cars and to multipurpose passenger vehicles... removable windshields. S4. Definitions. Daylight Opening (DLO) means the maximum unobstructed...

  16. Radiological risk of actinon (/sup 219/Rn)

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, D.J.

    1981-12-01

    The research reported was designed to provide information on the following subjects: (1) development of the functional relations between exposure to the /sup 219/Rn decay chain and pertinent health effects; (2) specification of the circumstances under which a significant concentration of the decay chain may occur; (3) recommendation of an exposure standard which will provide protection of the public from significant elevation of health effects; and (4) an assessment of the impact of /sup 219/Rn on determinations of the concentration of the /sup 222/Rn decay chain and/or its precursors.

  17. 36 CFR 219.9 - Revision.

    Science.gov (United States)

    2010-07-01

    ... Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.9 Revision. (a) Application... is a review of the overall management of a unit of the National Forest System and an opportunity...

  18. 36 CFR 219.7 - Plan decisions.

    Science.gov (United States)

    2010-07-01

    ... Forest System Land and Resource Management Planning The Framework for Planning § 219.7 Plan decisions... decisions generally do not commit resources to a site-specific action, plan decisions provide a framework... management actions necessary for the achievement of desired conditions and objectives and compliance...

  19. 49 CFR 219.23 - Railroad policies.

    Science.gov (United States)

    2010-10-01

    ... .02 or greater but less than .04. (12) Information concerning the effects of alcohol misuse on an..., DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE General § 219.23 Railroad policies. (a) Whenever a breath or body fluid test is required of an employee under this part, the railroad must...

  20. 48 CFR 219.7102 - General.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7102 General. The... negotiated under FAR Subpart 19.7 or under the DoD Comprehensive Subcontracting Test Program. (b) Protege...) Mentor-protege agreements that establish a developmental assistance program for a protege firm....

  1. 28 CFR 2.19 - Information considered.

    Science.gov (United States)

    2010-07-01

    ..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.19 Information...) Recommendations regarding the prisoner's parole made at the time of sentencing by the sentencing judge and... this section. (d) Recommendations and information from sentencing judges, defense...

  2. 49 CFR 219.603 - Participation in drug testing.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Participation in drug testing. 219.603 Section 219... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Random Alcohol and Drug Testing Programs § 219.603 Participation in drug testing. A railroad shall, under the conditions specified in this...

  3. 7 CFR 58.219 - High pressure pumps and lines.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false High pressure pumps and lines. 58.219 Section 58.219....219 High pressure pumps and lines. High pressure lines may be cleaned-in-place and shall be of such construction that dead ends, valves and the high pressure pumps can be disassembled for hand cleaning. The...

  4. 48 CFR 219.505 - Rejecting Small Business Administration recommendations.

    Science.gov (United States)

    2010-10-01

    ...-Asides for Small Business 219.505 Rejecting Small Business Administration recommendations. (b) The... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Rejecting Small Business Administration recommendations. 219.505 Section 219.505 Federal Acquisition Regulations System...

  5. 48 CFR 219.804 - Evaluation, offering, and acceptance.

    Science.gov (United States)

    2010-10-01

    ... Business Administration (The 8(a) Program) 219.804 Evaluation, offering, and acceptance. When processing... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Evaluation, offering, and acceptance. 219.804 Section 219.804 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  6. 49 CFR 219.301 - Testing for reasonable cause.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Testing for reasonable cause. 219.301 Section 219... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Testing for Cause § 219.301 Testing for reasonable cause. (a) Authorization. A railroad may, under the conditions specified in...

  7. 22 CFR 219.110 - Self-evaluation.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Self-evaluation. 219.110 Section 219.110... INTERNATIONAL DEVELOPMENT § 219.110 Self-evaluation. (a) The agency shall, by April 9, 1987, evaluate its... participate in the self-evaluation process by submitting comments (both oral and written). (c) The...

  8. 36 CFR 219.19 - Ecological, social, and economic sustainability.

    Science.gov (United States)

    2010-07-01

    ... economic sustainability. 219.19 Section 219.19 Parks, Forests, and Public Property FOREST SERVICE..., Social, and Economic Sustainability § 219.19 Ecological, social, and economic sustainability. Sustainability, composed of interdependent ecological, social, and economic elements, embodies the Multiple-Use...

  9. 36 CFR 219.21 - Social and economic sustainability.

    Science.gov (United States)

    2010-07-01

    ... sustainability. 219.21 Section 219.21 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF... Economic Sustainability § 219.21 Social and economic sustainability. To contribute to economic and social sustainability, the responsible official involves interested and affected people in planning for National Forest...

  10. 20 CFR 219.23 - Evidence to prove death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence to prove death. 219.23 Section 219... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.23 Evidence to prove death. (a) Preferred evidence of death. The best evidence of a person's death is— (1) A certified copy of or extract from...

  11. 20 CFR 219.8 - Preferred evidence and other evidence.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Preferred evidence and other evidence. 219.8 Section 219.8 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT EVIDENCE REQUIRED FOR PAYMENT General Evidence Requirements § 219.8 Preferred evidence and other evidence...

  12. 29 CFR 825.219 - Rights of a key employee.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Rights of a key employee. 825.219 Section 825.219 Labor....219 Rights of a key employee. (a) An employer who believes that reinstatement may be denied to a key... recover its cost of health benefit premiums. A key employee's rights under FMLA continue unless and...

  13. 36 CFR 219.5 - Information development and interpretation.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.5... scale, sometimes crossing Forest Service regional administrative boundaries. Ecological information...

  14. 49 CFR 219.501 - Pre-employment drug testing.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Pre-employment drug testing. 219.501 Section 219...-employment drug testing. (a) Prior to the first time a covered employee performs covered service for a railroad, the employee must undergo testing for drugs. No railroad may allow a covered employee to perform...

  15. 49 CFR 219.601 - Railroad random drug testing programs.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Railroad random drug testing programs. 219.601... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Random Alcohol and Drug Testing Programs § 219.601 Railroad random drug testing programs. (a) Submission. Each railroad must submit for FRA...

  16. 49 CFR 219.605 - Positive drug test results; procedures.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Random Alcohol and Drug Testing Programs § 219.605 Positive drug test results; procedures. (a) [Reserved] (b) Procedures for administrative... 49 Transportation 4 2010-10-01 2010-10-01 false Positive drug test results; procedures. 219.605...

  17. 9 CFR 93.219 - Declaration for poultry.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Declaration for poultry. 93.219 Section 93.219 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND...

  18. 49 CFR 219.205 - Specimen collection and handling.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Specimen collection and handling. 219.205 Section... § 219.205 Specimen collection and handling. (a) General. Urine and blood specimens must be obtained, marked, preserved, handled, and made available to FRA consistent with the requirements of this subpart...

  19. 49 CFR 1544.219 - Carriage of accessible weapons.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Carriage of accessible weapons. 1544.219 Section...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.219 Carriage of accessible weapons. (a... weapons, do not apply to a law enforcement officer (LEO) aboard a flight for which screening is required...

  20. 49 CFR 219.11 - General conditions for chemical tests.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  1. 42 CFR 93.219 - Preponderance of the evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Preponderance of the evidence. 93.219 Section 93.219 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH...

  2. 20 CFR 219.24 - Evidence of presumed death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of presumed death. 219.24 Section... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but evidence of death is needed, the Board may presume he or she died at a...

  3. 48 CFR 1852.219-73 - Small business subcontracting plan.

    Science.gov (United States)

    2010-10-01

    ... Provisions and Clauses 1852.219-73 Small business subcontracting plan. As prescribed in 1819.708-70(a), insert the following provision: Small Business Subcontracting Plan (MAY 1999) (a) This provision is not... contain FAR clause 52.219-9, “Small Business Subcontracting Plan.” The apparent low bidder must submit...

  4. 14 CFR 21.9 - Replacement and modification articles.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Replacement and modification articles. 21.9... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.9 Replacement and modification articles. (a) If a person knows, or should know, that a replacement or modification article is reasonably likely to...

  5. 18 CFR 2.19 - State and Federal comprehensive plans.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false State and Federal comprehensive plans. 2.19 Section 2.19 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of...

  6. 49 CFR 219.211 - Analysis and follow-up.

    Science.gov (United States)

    2010-10-01

    ...-accident toxicological testing under this subpart are reported to the railroad's Medical Review Officer and... Medical Review Officer may not disclose to FRA the underlying physical condition for which any medication... 49 Transportation 4 2010-10-01 2010-10-01 false Analysis and follow-up. 219.211 Section 219.211...

  7. 49 CFR 1542.219 - Supplementing law enforcement personnel.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Supplementing law enforcement personnel. 1542.219... Operations § 1542.219 Supplementing law enforcement personnel. (a) When TSA decides, after being notified by... private law enforcement personnel are available to carry out the requirements of § 1542.215, TSA may...

  8. 48 CFR 53.219 - Small Business Programs.

    Science.gov (United States)

    2010-10-01

    ... disadvantaged business (including Alaska Native Corporations and Indian tribes) and women-owned small business... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The...

  9. 50 CFR 300.219 - Vessel monitoring system.

    Science.gov (United States)

    2010-10-01

    ... system. (a) SAC and VMS Helpdesk contact information and business hours. The contact information for the..., Hawaii Standard Time. The contact information for the NOAA Office of Law Enforcement's VMS Helpdesk for the purpose of this section is: telephone: (888) 219-9228; e-mail: ole.helpdesk@noaa.gov. The...

  10. 20 CFR 725.219 - Duration of entitlement; child.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Duration of entitlement; child. 725.219... of entitlement; child. (a) An individual is entitled to benefits as a child for each month beginning... month in which any one of the following events first occurs: (1) The child dies; (2) The child...

  11. 36 CFR 219.25 - Science advisory boards.

    Science.gov (United States)

    2010-07-01

    ... social sciences. (b) Regional science advisory boards. Based upon needs identified by Regional Forester(s... including, but not limited to, the physical, biological, economic, and social sciences. Regional science...) Evaluating science consistency as described in § 219.24. (c) Work groups. With the concurrence of...

  12. 48 CFR 219.705-4 - Reviewing the subcontracting plan.

    Science.gov (United States)

    2010-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 219.705-4 Reviewing the subcontracting plan. (d) Challenge any subcontracting plan that... business goal of less than five percent must be approved one level above the contracting officer....

  13. 48 CFR 52.219-9 - Small business subcontracting plan.

    Science.gov (United States)

    2010-10-01

    ... Clauses 52.219-9 Small business subcontracting plan. As prescribed in 19.708(b), insert the following clause: Small Business Subcontracting Plan (OCT 2010) (a) This clause does not apply to small business... business, and women-owned small business concerns. If the offeror is submitting an individual contract...

  14. 29 CFR 1910.219 - Mechanical power-transmission apparatus.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Mechanical power-transmission apparatus. 1910.219 Section... Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all types and... apparatus located in basements. All mechanical power transmission apparatus located in basements,...

  15. 48 CFR 752.219-8 - Utilization of small business concerns and small disadvantaged business concerns.

    Science.gov (United States)

    2010-10-01

    ... business concerns and small disadvantaged business concerns. 752.219-8 Section 752.219-8 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 752.219-8 Utilization of small business...

  16. 48 CFR 552.219-72 - Preparation, Submission, and Negotiation of Subcontracting Plans.

    Science.gov (United States)

    2010-10-01

    ..., and Negotiation of Subcontracting Plans. 552.219-72 Section 552.219-72 Federal Acquisition Regulations... Text of Provisions and Clauses 552.219-72 Preparation, Submission, and Negotiation of Subcontracting... Negotiation of Subcontracting Plans (JUN 2005) (a) An offeror, other than a small business concern,...

  17. 40 CFR 80.219 - Designation and downstream requirements for GPA gasoline.

    Science.gov (United States)

    2010-07-01

    ... requirements for GPA gasoline. 80.219 Section 80.219 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-in Program § 80.219 Designation and downstream requirements for GPA gasoline. The requirements and... standards under § 80.216 as “GPA” gasoline. (b) Product transfer documents. (1) On each occasion that any...

  18. 36 CFR 219.31 - Maintenance of the plan and planning records.

    Science.gov (United States)

    2010-07-01

    ... planning records. 219.31 Section 219.31 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Planning Documentation § 219.31 Maintenance of the plan and planning records. (a) Each National Forest or Grassland...

  19. 36 CFR 219.22 - The overall role of science in planning.

    Science.gov (United States)

    2010-07-01

    ... in planning. 219.22 Section 219.22 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Contribution of Science § 219.22 The overall role of science in planning. (a) The responsible official must ensure that the...

  20. 48 CFR 52.219-7 - Notice of Partial Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ... the acquisition is for a product in a class for which the Small Business Administration has determined... Business Set-Aside. 52.219-7 Section 52.219-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-7 Notice of Partial Small Business Set-Aside. As prescribed in 19.508(d), insert...

  1. 48 CFR 52.219-6 - Notice of Total Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ... is for a product in a class for which the Small Business Administration has determined that there are... Business Set-Aside. 52.219-6 Section 52.219-6 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-6 Notice of Total Small Business Set-Aside. As prescribed in 19.508(c), insert...

  2. 76 FR 50810 - Seventh Meeting: RTCA Special Committee 219: Attitude and Heading Reference System

    Science.gov (United States)

    2011-08-16

    ... Committee 219 meeting: Attitude and Heading Reference System. SUMMARY: The FAA is issuing this notice to advise the public of a meeting of RTCA Special Committee 219: Attitude and Heading Reference System... Federal Aviation Administration Seventh Meeting: RTCA Special Committee 219: Attitude and...

  3. 75 FR 49550 - Fifth Meeting: RTCA Special Committee 219: Attitude and Heading Reference System (AHRS)

    Science.gov (United States)

    2010-08-13

    ...: Notice of RTCA Special Committee 219: Attitude and Heading Reference System (AHRS). SUMMARY: The FAA is issuing this notice to advise the public of a meeting of ] RTCA Special Committee 219: Attitude and... Federal Aviation Administration Fifth Meeting: RTCA Special Committee 219: Attitude and Heading...

  4. 36 CFR 219.12 - Collaboration and cooperatively developed landscape goals.

    Science.gov (United States)

    2010-07-01

    ... cooperatively developed landscape goals. 219.12 Section 219.12 Parks, Forests, and Public Property FOREST... Collaborative Planning for Sustainability § 219.12 Collaboration and cooperatively developed landscape goals. (a... process. (b) Cooperatively developed landscape goals. (1) The responsible official and other...

  5. 49 CFR 219.611 - Test result indicating prohibited alcohol concentration; procedures.

    Science.gov (United States)

    2010-10-01

    ... concentration; procedures. 219.611 Section 219.611 Transportation Other Regulations Relating to Transportation... concentration; procedures. Procedures for administrative handling by the railroad in the event an employee's confirmation test indicates an alcohol concentration of .04 or greater are set forth in § 219.104. ...

  6. Birth Defects Among Children Born to Human Immunodeficiency Virus-Infected Women Pediatric AIDS Clinical Trials Protocols 219 and 219C

    NARCIS (Netherlands)

    Brogly, Susan B.; Abzug, Mark J.; Watts, D. Heather; Cunningham, Coleen K.; Williams, Paige L.; Oleske, James; Conway, Daniel; Sperling, Rhoda S.; Spiegel, Hans; Van Dyke, Russell B.

    2010-01-01

    Background: Some studies have detected associations between in utero antiretroviral therapy (ARV) exposure and birth defects but evidence is inconclusive. Methods: A total of 2202 human immunodeficiency virus (HIV)-exposed children enrolled in the Pediatric AIDS Clinical Trials Group 219 and 219 C p

  7. Mass determination of K2-19b and K2-19c from radial velocities and transit timing variations

    CERN Document Server

    Nespral, D; Deeg, H J; Borsato, L; Fridlund, M C V; Barragan, O; Grziwa, S; Korth, J; Cabrera, J; Csizmadia, Sz; Nowak, G; Kuutma, T; Saario, J; Eigmuller, P; Erikson, A; Guenther, E W; Hatzes, A P; Rodriguez, P Montanes; Palle, E; Patzold, M; Prieto-Arranz, J; Rauer, H; Sebastian, D

    2016-01-01

    We present FIES@NOT and HARPS-N@TNG radial velocity follow-up observations of K2-19, a compact planetary system hosting three planets, of which the two larger ones, namely K2-19b and K2-19c, are close to the 3:2 mean motion resonance. The masses of these larger planets have previously been derived from transit timing only. An analysis considering only the radial velocity measurements is able to detect only K2-19b, the largest and more massive planet in the system, with a mass of $71.7\\pm6.3$ M${_\\oplus}$. We also used the TRADES code to simultaneously model both our RV measurements and the existing transit-timing measurements. We derived a mass of K2-19b of $59.5^{+7.2}_{-11.4}$ M${_\\oplus}$ and of K2-19c of $9.7^{+3.9}_{-2.0}$ M${_\\oplus}$. A prior K2-19b mass estimated by Barros 2015, based exclusively on transit timing measurements, is only consistent with our combined TTV and RV analysis, but not with our analysis based purely on RV measurements. K2-19b supports the suspicion that planet masses and densit...

  8. Anesthetic and surgical complications in 219 cases of myotonic dystrophy.

    Science.gov (United States)

    Mathieu, J; Allard, P; Gobeil, G; Girard, M; De Braekeleer, M; Bégin, P

    1997-12-01

    The objective of this study was to assess the frequency, type, and severity of perioperative complications after a first surgery under general anesthesia in patients with myotonic dystrophy (DM) and to measure the association with suspected risk factors. Numerous cases of perioperative complications in DM patients have been reported. Hazards have been associated with the use of thiopentone, suxamethonium, neostigmine, and halothane. A retrospective study of perioperative complications was conducted for 219 DM patients who had their first surgery under general anesthesia at the Chicoutimi Hospital. The overall frequency of complications was 8.2% (18 of 219). Most complications (16 of 18) were pulmonary, including five patients with acute ventilatory failure necessitating ventilatory support, four patients with atelectasis, and three patients with pneumonia. Using multivariate analysis, we found that the risk of perioperative pulmonary complications (PPC) was significantly higher after an upper abdominal surgery (odds ratio (OR), 24.4; 95% CI, 4.0 to 149.3) and for patients with a severe muscular disability, as assessed by the presence of proximal limb weakness (OR, 14.1; 95% CI, 1.5 to 134.4). The likelihood of PPC was not related to any specific anesthetic drug. Because of the increased risk of PPC, careful monitoring during the early postoperative period, protection of upper airways, chest physiotherapy, and incentive spirometry are mandatory in all symptomatic DM patients, particularly those with a severe muscular disability or those who have undergone an upper abdominal surgery.

  9. 36 CFR 219.16 - Relationships with interested individuals and organizations.

    Science.gov (United States)

    2010-07-01

    ... Planning for Sustainability § 219.16 Relationships with interested individuals and organizations. The... and frequent opportunities for participation in the identification of issues; (d) Encourage interested...

  10. 49 CFR 219.701 - Standards for drug and alcohol testing.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Standards for drug and alcohol testing. 219.701... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Drug and Alcohol Testing Procedures § 219.701 Standards for drug and alcohol testing. (a) Drug testing required or authorized by subparts B...

  11. 20 CFR 219.33 - Evidence of a deemed valid marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a deemed valid marriage. 219.33... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.33 Evidence of a deemed valid marriage. (a) Preferred evidence. Preferred evidence of a deemed valid marriage is— (1) Evidence of a ceremonial...

  12. 20 CFR 219.30 - When evidence of marriage is required.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When evidence of marriage is required. 219.30... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.30 When evidence of marriage is required. (a) When an application is filed for benefits. Documentary evidence of marriage is required when...

  13. 20 CFR 219.35 - Evidence that a marriage has ended.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence that a marriage has ended. 219.35... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.35 Evidence that a marriage has ended. (a) Preferred evidence. Preferred evidence that a marriage has ended is— (1) A certified copy of the decree...

  14. 20 CFR 219.32 - Evidence of a common-law marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a common-law marriage. 219.32... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.32 Evidence of a common-law marriage. (a) Preferred evidence. Evidence of a common-law marriage must give the reasons why the informant believes...

  15. 32 CFR 219.118 - Applications and proposals lacking definite plans for involvement of human subjects.

    Science.gov (United States)

    2010-07-01

    ... plans for involvement of human subjects. 219.118 Section 219.118 National Defense Department of Defense....118 Applications and proposals lacking definite plans for involvement of human subjects. Certain types... agencies with the knowledge that subjects may be involved within the period of support, but definite...

  16. 25 CFR 166.219 - How do I acquire a permit through negotiation?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How do I acquire a permit through negotiation? 166.219... PERMITS Permit Requirements Obtaining A Permit § 166.219 How do I acquire a permit through negotiation? (a...) Upon the conclusion of negotiations with the Indian landowners or their representatives, and...

  17. 32 CFR 219.123 - Early termination of research support: Evaluation of applications and proposals.

    Science.gov (United States)

    2010-07-01

    ....123 Early termination of research support: Evaluation of applications and proposals. (a) The... 32 National Defense 2 2010-07-01 2010-07-01 false Early termination of research support: Evaluation of applications and proposals. 219.123 Section 219.123 National Defense Department of...

  18. 48 CFR 52.219-4 - Notice of price evaluation preference for HUBZone small business concerns.

    Science.gov (United States)

    2010-10-01

    ... successful offers from small business concerns. (2) The factor of 10 percent shall be applied on a line item... preference for HUBZone small business concerns. 52.219-4 Section 52.219-4 Federal Acquisition Regulations... business concerns. As prescribed in 19.1308(b), insert the following clause: Notice of Price...

  19. 48 CFR 52.219-23 - Notice of Price Evaluation Adjustment for Small Disadvantaged Business Concerns.

    Science.gov (United States)

    2010-10-01

    ... disadvantaged business concern in accordance with 13 CFR 124, subpart B, and a decision on that application is... disadvantaged business concerns that have not waived the adjustment; and (ii) An otherwise successful offer from... Adjustment for Small Disadvantaged Business Concerns. 52.219-23 Section 52.219-23 Federal...

  20. 76 FR 80447 - Eighth Meeting: RTCA Special Committee 219: Attitude and Heading Reference Systems (AHRS)

    Science.gov (United States)

    2011-12-23

    ... Federal Aviation Administration Eighth Meeting: RTCA Special Committee 219: Attitude and Heading Reference...). ACTION: Notice of RTCA Special Committee 219: Attitude and Heading Reference Systems (AHRS). SUMMARY: The FAA is issuing this notice to advise the public of the eighth meeting of RTCA Special Committee...

  1. 49 CFR 219.102 - Prohibition on abuse of controlled substances.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Prohibition on abuse of controlled substances. 219....102 Prohibition on abuse of controlled substances. No employee who performs covered service may use a controlled substance at any time, whether on duty or off duty, except as permitted by § 219.103....

  2. 48 CFR 2452.219-70 - Small business subcontracting plan compliance.

    Science.gov (United States)

    2010-10-01

    ... of Provisions and Clauses 2452.219-70 Small business subcontracting plan compliance. As prescribed in 2419.708(d), insert the following provision: Small Business Subcontracting Plan Compliance (FEB 2006... the clause at FAR 52.219-9, Small Business Subcontracting Plan. (c) The government will...

  3. 48 CFR 652.219-70 - Department of State Subcontracting Goals.

    Science.gov (United States)

    2010-10-01

    ... Subcontracting Goals. 652.219-70 Section 652.219-70 Federal Acquisition Regulations System DEPARTMENT OF STATE... Department of State Subcontracting Goals. As prescribed in 619.708-70, insert a provision substantially the same as follows: Department of State Subcontracting Goals (APR 2004) (a) The offeror shall provide...

  4. 20 CFR 219.53 - Evidence of having a child in care.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of having a child in care. 219.53... EVIDENCE REQUIRED FOR PAYMENT Other Evidence Requirements § 219.53 Evidence of having a child in care. (a) Preferred evidence of having a child in care. Preferred evidence of having a child in care is— (1) If...

  5. 49 CFR 238.219 - Truck-to-car-body attachment.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Truck-to-car-body attachment. 238.219 Section 238... I Passenger Equipment § 238.219 Truck-to-car-body attachment. Passenger equipment shall have a truck-to-car-body attachment with an ultimate strength sufficient to resist without failure the...

  6. Extraction and purification of {sup 227}Ac and development of solid {sup 219}Rn source

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Quan; Qiu, Shoukang; Xiao, Detao; Zhou, Yaohui; An, Xiaogang [University of South China, Hengyang (China). Radon Key Laboratory of Hunan Province/School of Nuclear Science and Technology

    2014-04-01

    The method of {sup 227}Ac extraction and purification from high-grade uranium ore and the test results of solid {sup 219}Rn source made from {sup 227}Ac are reported in this paper. With five years of follow-up monitoring, radiochemical purity of {sup 227}Ac and the emanation power of solid {sup 219}Rn source has been checked by emanation method and γ-spectrometry, the results showed that {sup 228}Th, {sup 231}Pa and {sup 226}Ra have been effectively removed and the emanation power of {sup 219}Rn source is about 80%. The long-term test results also showed that the {sup 219}Rn emanation rate remains stable in a wide air humidity range (40% ∝ 90%). Though the {sup 219}Rn source has not been accurately calibrated yet, it has been applied in the research for delay coincidence measurement of {sup 223}Ra. (orig.)

  7. Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

    Science.gov (United States)

    Santa-Maria, Ismael; Alaniz, Maria E.; Renwick, Neil; Cela, Carolina; Fulga, Tudor A.; Van Vactor, David; Tuschl, Thomas; Clark, Lorraine N.; Shelanski, Michael L.; McCabe, Brian D.; Crary, John F.

    2015-01-01

    Tau is a highly abundant and multifunctional brain protein that accumulates in neurofibrillary tangles (NFTs), most commonly in Alzheimer’s disease (AD) and primary age-related tauopathy. Recently, microRNAs (miRNAs) have been linked to neurodegeneration; however, it is not clear whether miRNA dysregulation contributes to tau neurotoxicity. Here, we determined that the highly conserved brain miRNA miR-219 is downregulated in brain tissue taken at autopsy from patients with AD and from those with severe primary age-related tauopathy. In a Drosophila model that produces human tau, reduction of miR-219 exacerbated tau toxicity, while overexpression of miR-219 partially abrogated toxic effects. Moreover, we observed a bidirectional modulation of tau levels in the Drosophila model that was dependent on miR-219 expression or neutralization, demonstrating that miR-219 regulates tau in vivo. In mammalian cellular models, we found that miR-219 binds directly to the 3′-UTR of the tau mRNA and represses tau synthesis at the post-transcriptional level. Together, our data indicate that silencing of tau by miR-219 is an ancient regulatory mechanism that may become perturbed during neurofibrillary degeneration and suggest that this regulatory pathway may be useful for developing therapeutics for tauopathies. PMID:25574843

  8. 47 CFR 95.219 - (R/C Rule 19) How do I answer correspondence from the FCC?

    Science.gov (United States)

    2010-10-01

    ... from the FCC? 95.219 Section 95.219 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... You Need to Know § 95.219 (R/C Rule 19) How do I answer correspondence from the FCC? (a) If it appears to the FCC that you have violated the Communications Act or FCC rules, the FCC may send you...

  9. 32 CFR 219.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Science.gov (United States)

    2010-07-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 219.120 Section 219...) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.120 Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. (a) The department...

  10. 18 CFR 367.2190 - Account 219, Accumulated other comprehensive income.

    Science.gov (United States)

    2010-04-01

    ... POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Proprietary Capital § 367.2190 Account 219... FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY...

  11. 49 CFR 219.602 - FRA Administrator's determination of random drug testing rate.

    Science.gov (United States)

    2010-10-01

    ... Random Alcohol and Drug Testing Programs § 219.602 FRA Administrator's determination of random drug... percentage rate for random drug testing must be 50 percent of covered employees. (b) The FRA Administrator's decision to increase or decrease the minimum annual percentage rate for random drug testing is based on the...

  12. 20 CFR 219.31 - Evidence of a valid ceremonial marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a valid ceremonial marriage. 219... marriage. (a) Preferred evidence. Preferred evidence of a ceremonial marriage is— (1) A copy of the public record of the marriage, certified by the custodian of the record or by a Board employee; (2) A copy of...

  13. 27 CFR 28.219 - Return of wine withdrawn for export with benefit of drawback.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Return of wine withdrawn... Exportation of Wine With Benefit of Drawback § 28.219 Return of wine withdrawn for export with benefit of drawback. When notice is filed by an exporter as provided in § 28.220, wine on which the tax has been...

  14. 36 CFR 219.14 - Involvement of State and local governments.

    Science.gov (United States)

    2010-07-01

    ... OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for Sustainability § 219.14 Involvement of State and local governments. The responsible official... the planning process, including the identification of issues; and (b) Contribute to the...

  15. 48 CFR 219.7104 - Developmental assistance costs eligible for reimbursement or credit.

    Science.gov (United States)

    2010-10-01

    ... BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7104 Developmental assistance costs eligible for reimbursement or credit. (a) Developmental assistance provided under an approved mentor-protege agreement is... debarred while performing under an approved mentor-protege agreement, the mentor firm may not be...

  16. 48 CFR 252.219-7004 - Small business subcontracting plan (test program).

    Science.gov (United States)

    2010-10-01

    ... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan... contract or subcontract. (b) The Offeror's comprehensive small business subcontracting plan and its... “Utilization of Small Business Concerns,” or (2) an approved plan required by this clause, shall be a...

  17. 48 CFR 852.219-9 - VA Small business subcontracting plan minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... Provisions and Clauses 852.219-9 VA Small business subcontracting plan minimum requirements. As prescribed in subpart 819.709, insert the following clause: VA Small Business Subcontracting Plan Minimum Requirements... plan, the minimum goals for award of subcontracts to service-disabled veteran-owned small...

  18. 36 CFR 223.219 - Sustainable harvest of special forest products.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Sustainable harvest of....219 Sustainable harvest of special forest products. (a) Sustainable harvest levels. Prior to offering... product's sustainable harvest level. A special forest product's sustainable harvest level is the...

  19. Occurrence of rhyolytic tuffs at deep sea drilling project site 219 on the Laccadive Ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Siddiquie, H.N.; Sukheswala, R.N.

    A study of thin sections from the lower and middle parts of Unit 5 (Paleocene) from Site 219 shows that these largely consist of acidic or rhyolitic tuffs. The overlying limestones in Unit 5 (Paleocene) and Unit 4 (Lower Eocene) also contain...

  20. 48 CFR 52.219-19 - Small Business Concern Representation for the Small Business Competitiveness Demonstration Program.

    Science.gov (United States)

    2010-10-01

    ... Representation for the Small Business Competitiveness Demonstration Program. 52.219-19 Section 52.219-19 Federal... Representation for the Small Business Competitiveness Demonstration Program. As prescribed in 19.1008(a), insert the following provision: Small Business Concern Representation for the Small Business...

  1. 50 CFR 226.219 - Critical habitat for the Southern Distinct Population Segment of North American Green Sturgeon...

    Science.gov (United States)

    2010-10-01

    ... coastal marine areas is defined by the zone between the 60 fathom (fm) depth bathymetry line and the line... Population Segment of North American Green Sturgeon (Acipenser medirostris). 226.219 Section 226.219 Wildlife... Distinct Population Segment of North American Green Sturgeon (Acipenser medirostris). Critical habitat is...

  2. 38 CFR 21.219 - Supplies consisting of clothing, magazines and periodicals, and items which may be personally...

    Science.gov (United States)

    2010-07-01

    ... clothing, magazines and periodicals, and items which may be personally used by the veteran. 21.219 Section....219 Supplies consisting of clothing, magazines and periodicals, and items which may be personally used... will be supplied. (b) Furnishing magazines and periodicals. Appropriate past issues of...

  3. 41 CFR 302-3.219 - Is there a limit on how many times I may receive reimbursement for tour renewal travel?

    Science.gov (United States)

    2010-07-01

    ... many times I may receive reimbursement for tour renewal travel? 302-3.219 Section 302-3.219 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION....219 Is there a limit on how many times I may receive reimbursement for tour renewal travel? (a) If you...

  4. Conceptual design report, 219-S secondary containment upgrade, Project W-178

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, J.J. [Kaiser Engineers Hanford Co., Richland, WA (United States)

    1993-05-01

    The 219-S Facility is located in the 200-West Area on the Hanford Site and was constructed in 1951. The facility receives and treats liquid, low-level mixed waste from the 222-S Laboratory prior to transfer of that waste to the SY Tank Farm. The 219-S Facility consists of Cell A containing Tanks 101 and 102 and Cell B containing Tank 103 and a spare space. Project W-178 will modify the 219-S Facility to bring it into compliance with the tank system standards in WAC 173-303-640. The secondary containment upgrade will consist of a stainless steel cell liner in both Cell A and the spare space in Cell B. Additionally, Cell B will be modified by taking Tank 103 out of service and installing a new tank: Tank 104. The construction work will be accomplished in phases to minimize service interruption to the 222-S Laboratory. The proposed design and construction method is the most cost effective of four alternatives evaluated during a value engineering session. Project W-178 is a fiscal year 1995 Line Item. Total estimated construction costs of the project are $2,600,000; other project costs are $710,000. The total project cost is $3,300,000.

  5. Field Trial of 40 Gbit/s ETDM Prototype System over 219 km of Installed Single Mode Fiber

    Institute of Scientific and Technical Information of China (English)

    Sang Soo Lee; Hyun Woo Cho; Sang Kyu Lim; Ki Ho Han; Jin Soo Han; Moo Jung Chu; Je Soo Ko; Kyeong-Mo Yoon; Yong-Gi Lee

    2003-01-01

    Transmission of 40Gbit/s NRZ signal was successfully demonstrated over 219km of installed SMF in KT's Daejeon area network. After transmission, the measured power penalty was 0.5dB for all the tributary channels.

  6. Differences in ABCA1 R219K Polymorphisms and Serum Indexes in Alzheimer and Parkinson Diseases in Northern China.

    Science.gov (United States)

    Ya, Lagai; Lu, Zuneng

    2017-09-25

    BACKGROUND ABCA1 R219K single-nucleotide polymorphisms (SNPs) was related to Alzheimer disease (AD) but not Parkinson disease (PD). Here, we analyzed the associations among ABCA1 R219K distribution, serum biomarkers, AD, and PD in a population in northern China. MATERIAL AND METHODS We used the Mini-Mental State Examination (MMSE) and the Hoehn and Yahr scale (H-Y) to evaluate AD and PD progression, separately. ABCA1 R219K was analyzed by matrix-assisted laser desorption ionization time of flight time mass spectrometry (MALDI-TOF-MS). Serum indexes were determined by enzyme-linked immunosorbent assay (ELISA). RESULTS ABCA1 R219K RR+RK genotype frequency in AD and PD patients was lower than that in normal controls (NC), while ABCA1 R219K KK genotype frequency was significantly higher. ABCA1 R219K RR genotype frequency in AD patients and NC was lower than that in PD patients, while ABCA1 R219K RK+KK genotype frequency was significantly higher. ABCA1 R219K RR genotype was positively correlated to MMSE value in AD patients, while ABCA1 R219K KK genotype was negatively correlated to H-Y value in PD patients. Serum factors were significantly different among AD and PD patients and NC. Serum ABCA1, ApoA1, ApoA2, ApoB, HDL, TC, IL-1β, IL-6, and TNF-α were significantly different between AD and PD patients. CONCLUSIONS ABCA1 R219K R allele was the risk factor inducing abnormal serum levels of ApoA2, LDL, and TG in AD patients, and abnormal levels of serum ABCA1, HDL, IL-1b, IL-6, and TNF-α in PD patients, while ABCA1 R219K K allele was the risk factor inducing lower ABCA1 in AD patients. IL-1β, IL-6, and TNF-α were negatively correlated to MMSE in AD patients but positively correlated to H-Y in PD patients, while HDL was positively related to H-Y in PD patients.

  7. Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation

    Science.gov (United States)

    Chen, Chun-Yen; Ho, Sih-Syun; Kuo, Tzu-Yen; Cheng, Yi-Sheng

    2017-01-01

    Far-red (FR) light-coupled jasmonate (JA) signaling is necessary for plant defense and development. FR insensitive 219 (FIN219) is a member of the Gretchen Hagen 3 (GH3) family of proteins in Arabidopsis and belongs to the adenylate-forming family of enzymes. It directly controls biosynthesis of jasmonoyl-isoleucine in JA-mediated defense responses and interacts with FIN219-interacting protein 1 (FIP1) under FR light conditions. FIN219 and FIP1 are involved in FR light signaling and are regulators of the interplay between light and JA signaling. However, how their interactions affect plant physiological functions remains unclear. Here, we demonstrate the crystal structures of FIN219–FIP1 while binding with substrates at atomic resolution. Our results show an unexpected FIN219 conformation and demonstrate various differences between this protein and other members of the GH3 family. We show that the rotated C-terminal domain of FIN219 alters ATP binding and the core structure of the active site. We further demonstrate that this unique FIN219–FIP1 structure is crucial for increasing FIN219 activity and determines the priority of substrate binding. We suggest that the increased FIN219 activity resulting from the complex form, a conformation for domain switching, allows FIN219 to switch to its high-affinity mode and thereby enhances JA signaling under continuous FR light conditions. PMID:28223489

  8. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.

    Science.gov (United States)

    Murai, Kiyohito; Sun, Guoqiang; Ye, Peng; Tian, E; Yang, Su; Cui, Qi; Sun, Guihua; Trinh, Daniel; Sun, Olivia; Hong, Teresa; Wen, Zhexing; Kalkum, Markus; Riggs, Arthur D; Song, Hongjun; Ming, Guo-li; Shi, Yanhong

    2016-03-11

    Dysregulated expression of miR-219, a brain-specific microRNA, has been observed in neurodevelopmental disorders, such as schizophrenia (SCZ). However, its role in normal mammalian neural stem cells (NSCs) and in SCZ pathogenesis remains unknown. We show here that the nuclear receptor TLX, an essential regulator of NSC proliferation and self-renewal, inhibits miR-219 processing. miR-219 suppresses mouse NSC proliferation downstream of TLX. Moreover, we demonstrate upregulation of miR-219 and downregulation of TLX expression in NSCs derived from SCZ patient iPSCs and DISC1-mutant isogenic iPSCs. SCZ NSCs exhibit reduced cell proliferation. Overexpression of TLX or inhibition of miR-219 action rescues the proliferative defect in SCZ NSCs. Therefore, this study uncovers an important role for TLX and miR-219 in both normal neurodevelopment and in SCZ patient iPSC-derived NSCs. Moreover, this study reveals an unexpected role for TLX in regulating microRNA processing, independent of its well-characterized role in transcriptional regulation.

  9. VizieR Online Data Catalog: K2-19b light curve (Armstrong+, 2015)

    Science.gov (United States)

    Armstrong, D. J.; Santerne, A.; Veras, D.; Barros, S. C. C.; Demangeon, O.; Lillo-Box, J.; McCormac, J.; Osborn, H. P.; Tsantaki, M.; Almenara, J.-M.; Barrado, D.; Boisse, I.; Bonomo, A. S.; Brown, D. J. A.; Bruno, G.; Rey Cerda, J.; Courcol, B.; Deleuil, M.; Diaz, R. F.; Doyle, A. P.; Hebrard, G.; Kirk, J.; Lam, K. W. F.; Pollacco, D. L.; Rajpurohit, A.; Spake, J.; Walker, S. R.

    2015-08-01

    The Near Infrared Transiting ExoplanetS (NITES) Telescope is a semi-robotic 0.4m (f/10) Meade LX200GPS Schmidt-Cassegrain telescope installed at the ORM, La Palma. One transit of K2-19b was observed on 2015 Feb 28. The telescope was defocused slightly to 3.3 FWHM and 814 images of 20s exposure time were obtained with 5s dead time between each. Observations were obtained without a filter. The table presents data taken with the NITES telescope shown in Figure 1 of the publication. (1 data file).

  10. Inverse Compton X-rays from the radio galaxy 3C 219

    CERN Document Server

    Comastri, A; Dallacasa, D; Bondi, M; Pedani, M; Setti, G

    2003-01-01

    We report the results from a Chandra observation of the powerful nearby (z=0.1744) radio galaxy 3C 219. We find evidence for non-thermal X-ray emission from the radio lobes which fits fairly well with a combination of inverse Compton scattering of Cosmic Microwave Background radiation and of nuclear photons with the relativistic electrons in the lobes. The comparison between radio synchrotron and IC emission yields a magnetic field strength significantly lower (about a factor 3) than that calculated under minimum energy conditions; the source energetics is then dominated by the relativistic particles.

  11. 温室专用番茄新品种‘冀东219'%A New Tomato Cultivar for Greenhouse Jidong 219

    Institute of Scientific and Technical Information of China (English)

    孙中峰; 曹霞; 武春成; 毛秀杰; 代波; 王学东

    2012-01-01

    Jidong 219 is a F1 by several generations of screening and crossing with import tomato. It has unlimited branches and sparse leaves and it grows vigorously. The first inflorescence is situated between the sixth and ninth node, inflorescence interval of 2 to 3, and each inflorescence bears 8 - 15 tomatos. The average fruit mass is 38 - 42 g. The fruit is red, round. Fruit shape index is 0.89. Vitamin C content is 0.17 mg.g-1. The soluble solids content is 6.18%. Organic acid content is 0.79%. Ratio of sugar to acid is 7.82. Fruit is sweet and sour, flesh is thick. It is tolerant to storage and transportation. It is high-resistant to TYLCV, TMV, southern bacterial wilt and leaf mold, and mid-resistant to gray mold. It is suitable for protected cultivation.%番茄杂种一代新品种‘冀东219’,植株为无限生长类型,叶片较稀疏,生长势较强,第6-9节着生第一花序,花序间隔2-3节,每穗结果8-15个。单果质量38-42g,果实红色,圆形,果面光滑,果形指数0.89,果实中维生素C含量为0.17mg·g-1,可溶性固型物含量为6.18%,有机酸含量为0.79%,糖酸比为7.82,酸甜适口,果肉较厚,耐贮运。高抗TYLCV、TMV、青枯病、叶霉病,中抗灰霉病。适合保护地栽培。

  12. Photo-dynamical mass determination of the multi-planetary system K2-19

    CERN Document Server

    Barros, S C C; Demangeon, O; Tsantaki, M; Santerne, A; Armstrong, D J; Barrado, D; Brown, D; Deleuil, M; Lillo-Box, J; Osborn, H; Pollacco, D; Abe, L; Andre, P; Bendjoya, P; Boisse, I; Bonomo, A S; Bouchy, F; Bruno, G; Cerda, J Rey; Courcol, B; Díaz, R F; Hébrard, G; Kirk, J; Lachurié, J C; Lam, K W F; Martinez, P; McCormac, J; Moutou, C; Rajpurohit, A; Rivet, J -P; Spake, J; Suarez, O; Toublanc, D; Walker, S R

    2015-01-01

    K2-19 is the second multi-planetary system discovered with K2 observations. The system is composed of two Neptune size planets close to the 3:2 mean-motion resonance. To better characterise the system we obtained two additional transit observations of K2-19b and five additional radial velocity observations. These were combined with K2 data and fitted simultaneously with the system dynamics (photo-dynamical model) which increases the precision of the transit time measurements. The higher transit time precision allows us to detect the chopping signal of the dynamic interaction of the planets that in turn permits to uniquely characterise the system. Although the reflex motion of the star was not detected, dynamic modelling of the system allowed us to derive planetary masses of $M_b= 44 \\pm 12\\, M_{\\oplus}$ and $M_c = 15.9 \\pm 7.0\\, M_{\\oplus}$ for the inner and the outer planets respectively, leading to densities close to Uranus. We also show that our method allows the derivation of mass ratios using only the 80...

  13. Marker-assisted introgression of broad-spectrum blast resistance genes into the cultivated MR219 rice variety.

    Science.gov (United States)

    Miah, Gous; Rafii, Mohd Y; Ismail, Mohd R; Puteh, Adam B; Rahim, Harun A; Latif, Mohammad A

    2017-07-01

    The rice cultivar MR219 is famous for its better yield and long and fine grain quality; however, it is susceptible to blast disease. The main objective of this study was to introgress blast resistance genes into MR219 through marker-assisted selection (MAS). The rice cultivar MR219 was used as the recurrent parent, and Pongsu Seribu 1 was used as the donor. Marker-assisted foreground selection was performed using RM6836 and RM8225 to identify plants possessing blast resistance genes. Seventy microsatellite markers were used to estimate recurrent parent genome (RPG) recovery. Our analysis led to the development of 13 improved blast resistant lines with Piz, Pi2 and Pi9 broad-spectrum blast resistance genes and an MR219 genetic background. The RPG recovery of the selected improved lines was up to 97.70% with an average value of 95.98%. Selected improved lines showed a resistance response against the most virulent blast pathogen pathotype, P7.2. The selected improved lines did not express any negative effect on agronomic traits in comparison with MR219. The research findings of this study will be a conducive approach for the application of different molecular techniques that may result in accelerating the development of new disease-resistant rice varieties, which in turn will match rising demand and food security worldwide. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  14. Effect of miR-219-5p on malignant phenotype of glioblastoma cells%MiR-219-5p对人脑成胶质细胞瘤恶性表型的影响

    Institute of Scientific and Technical Information of China (English)

    刘彦伟; 颜伟; 王永志; 张伟; 游赣; 唐铠

    2012-01-01

    目的:探讨miR-219-5p对人脑成胶质细胞瘤(glioblastoma,GBM)的恶性表型——增殖、凋亡和侵袭的影响,初步寻找与miR-219-5p发挥抑癌作用有关的靶点基因.方法:在60例GBM组织中分析miR-219-5p表达水平及mRNA表达谱,筛选与miR-219-5p表达量呈负相关的mRNA;选取前50个相关性最大的mRNA,用基因功能分析软件DAVID从中筛选出与GBM恶性进展相关的2组mRNA;最后用4个在线靶点预测网站从这2组中预测miR-219-5p的潜在靶点.采用MTT法、流式细胞术和Transwell实验初步验证miR-219-5p对GBM细胞增殖、凋亡和侵袭的影响.结果:60例GBM组织中筛出14个与增殖和凋亡相关的基因和5个与侵袭相关的基因(P<0.001);在这19个候选基因中预测到4个基因(TWIST1、MYO1B、WEE1和SPRED2)是miR-219-5p的潜在靶点.实验初步证明,miR-219-5p能够抑制GBM细胞的增殖和侵袭以及促进细胞凋亡(P<0.05).结论:MiR-219-5p可能通过作用于多个靶点对GBM的恶性表型起到抑制作用.%Objective: To investigate the effect of rniR-219-5p on malignant phenotype of glioblastoma cells involving proliferation, apoptosis and invasion, and to preliminarily determine the candidate target genes of miR-219-5p related to the inhibition of cancer. Methods: The inverse relationship between mRNAs and miR-219-5p in glioblastoma tissues from sixty cases was obtained by analysis of miR-219-5p expression level and mRNA expression profiling. DAVID software for functional analysis was employed to analyze the functions of the top 50 mRNAs and screen out two sets of mRNAs related to glioblastoma progression. The target genes of miR-219-5p were screened out from the two sets of miRNAs on four websites of online target-binding prediction. MTT assay, flow cytometry (FCM) assay and Transwell assay were performed to detect the effects of miR-219-5p on the proliferation, apoptosis and invasion of human glioblastoma cells, respectively. Results: Fourteen

  15. 固体219Rn 源的γ能谱法放射性纯度检验%Determination of Radioactivity Purity of Solid 219 Rn Source by γ-ray Spectrometry

    Institute of Scientific and Technical Information of China (English)

    唐泉; 安小刚; 丘寿康

    2014-01-01

    对利用从铀矿石中提取得到的227 Ac制备的固体219 Rn源进行了γ能谱分析,确定了227 Ac的4个子体核素227 T h、223 Ra、219 Rn和211 Bi的活度,并分析了能对219 Rn造成干扰的222 Rn、220 Rn母体核素226 Ra、224 Ra的活度。待227 Ac及其子体达到放射性平衡后,通过测量227 Th的235.97、256.25 keV ,223 Ra的154.21 keV ,219 Rn的401.81 keV ,211 Bi的351.059 keV共5条γ射线,最终确定固体219 Rn源中227 T h、223 Ra、219 Rn和211 Bi的活度为(1069±3)、(1079±5)、(1095±13)、(1096±14)和(11089±4) Bq ,固体219 Rn源的平均活度为(1093±8) Bq;通过测量224 Ra子体212 Pb的238.632 keV、208 T l的583.191 keVγ射线以及226 Ra子体214 Bi的609.312、1120.287 keV γ射线得到226 Ra与224 Ra的平均活度分别为5.12 Bq及0.433 Bq ,远低于固体219 Rn源的平均活度,说明固体219 Rn源放射性纯度较高。以上结果表明,此源有望制成标准固体219 Rn源以用于延迟符合法测223 Ra、227 Ac装置的刻度。%Radioactivity purity of the solid 219 Rn source made using 227 Ac extracted from uranium ore were determined by γ‐spectrometry .The activities of 227 Th ,223 Ra ,219 Rn and 211 Bi produced by the decay of 227 Ac and the contents of 226 Ra ,224 Ra w hich generates 222 Rn ,220 Rn to affect the purity of actinide in this source were analyzed after 227 Ac in radioactive equilibrium with its daughter nuclides . The γ‐ray energy used for the determination of these daughter nuclides of 227 Ac are 235.97 ,256.25 keV for 227 Th , 154.21 keV for 223Ra ,401.81 keV for 219Rn ,and 351.059 keV for 211Bi .Through the analysis ,the results are acquired that their activities are (1 069 ± 3 ) , (1 079 ± 5 ) , (1 095 ± 13) ,(1 096 ± 14) and (11 089 ± 4) Bq respectively ,and the average activity of solid 219 Rn source is (1 093 ± 8) Bq .The activities of 226 Ra and 224 Ra in this source are 5.12 Bq and 0.433 Bq respectively

  16. 48 CFR 1052.219-73 - Department of the Treasury Mentor-Protégé Program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Department of the Treasury... DEPARTMENT OF THE TREASURY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1052.219-73 Department of the Treasury Mentor-Protégé Program. As described in DTAR...

  17. Expression of NMDA receptor and microRNA-219 in rats submitted to cerebral ischemia associated with alcoholism

    Directory of Open Access Journals (Sweden)

    Cristiane Iozzi Silva

    Full Text Available ABSTRACT Alcohol consumption aggravates injuries caused by ischemia. Many molecular mechanisms are involved in the pathophysiology of cerebral ischemia, including neurotransmitter expression, which is regulated by microRNAs. Objective: To evaluate the microRNA-219 and NMDA expression in brain tissue and blood of animals subjected to cerebral ischemia associated with alcoholism. Methods: Fifty Wistar rats were divided into groups: control, sham, ischemic, alcoholic, and ischemic plus alcoholic. The expression of microRNA-219 and NMDA were analyzed by real-time PCR. Results: When compared to the control group, the microRNA-219 in brain tissue was less expressed in the ischemic, alcoholic, and ischemic plus alcoholic groups. In the blood, this microRNA had lower expression in alcoholic and ischemic plus alcoholic groups. In the brain tissue the NMDA gene expression was greater in the ischemic, alcoholic, and ischemic plus alcoholic groups. Conclusion: A possible modulation of NMDA by microRNA-219 was observed with an inverse correlation between them.

  18. 48 CFR 52.219-27 - Notice of Total Service-Disabled Veteran-Owned Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ...-Disabled Veteran-Owned Small Business Set-Aside (MAY 2004) (a) Definition. Service-disabled veteran-owned... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Notice of Total Service... CONTRACT CLAUSES Text of Provisions and Clauses 52.219-27 Notice of Total Service-Disabled...

  19. 32 CFR 219.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Assuring compliance with this policy-research... HUMAN SUBJECTS § 219.103 Assuring compliance with this policy—research conducted or supported by any Federal Department or Agency. (a) Each institution engaged in research which is covered by this policy...

  20. Enhancing somatic embryogenesis of Malaysian rice cultivar MR219 using adjuvant materials in a high-efficiency protocol

    DEFF Research Database (Denmark)

    Rambod, Abiri; Maziah, Mahmood; Shaharuddin, Noor Azmi

    2017-01-01

    Enhancing of the efficient tissue culture protocol for somatic embryos would facilitate the engineered breeding plants program. In this report, we describe the reproducible protocol of Malaysian rice (Oryza sativa L.) cultivar MR219 through somatic embryogenesis. Effect of a wide spectrum...

  1. 77 FR 62346 - Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195; Denial of Request for Redactions

    Science.gov (United States)

    2012-10-12

    .../a CVS/Pharmacy Nos. 219 and 5195; Denial of Request for Redactions On August 31, 2012, I issued a... Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195 (hereinafter, Respondents). Prior to publication... manner in which information was obtained for Respondents' pharmacy information management system...

  2. MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.

    Directory of Open Access Journals (Sweden)

    Huizi Lei

    Full Text Available BACKGROUND AIMS: Gastric cancer is the most frequent gastrointestinal tumor in adults and is the most lethal form of human cancer. Despite of the improvements in treatments, the underlying mechanism of gastric carcinogenesis is not well known. To define novel modulators that regulate susceptibility to tumorgenesis, we focused on miR-219-2-3p. METHODS: Quantitative RT-PCR was employed to investigate the level of miR-219-2-3p in gastric cancer (GC tissues (n = 113 and their matched adjacent normal tissues (n = 113. In vitro cell proliferation, apoptosis assays, cell migration, and invasion assays were performed to elucidate biological effects of miR-219-2-3p. Since silencing of miRNA by promoter CpG island methylation may be an important mechanism in tumorgenesis, GC cells were treated with 5-aza-2'-deoxycytidine and trichostatin A, and expression changes of miR-219-2-3p were subsequently examined by quantitative RT-PCR. Finally, the methylation status of CpG island upstream of miR-219-2-3p was analyzed by methylation-specific PCR in GC tissues (n = 22. RESULTS: miR-219-2-3p was down-regulated in GC and cell lines. In addition, the experiments documented the lower expression of miR-219-2-3p in GC specimens with higher grade and later stage tumors. Meanwhile, miR-219-2-3p exerted antiproliferative, proapoptotic, and antimetastatic roles and reduced levels of p-ERK1/2 in GC cells. Furthermore, 5-aza-2'-deoxycytidine and trichostatin A increased the expression (~2 fold of miR-219-2-3p in GC cells. By methylation-specific PCR, DNA methylation in the upstream region of miR-219-2-3p was detected in both adjacent normal tissues and cancer tissues. As expected, the methylation level was considerably higher in the miR-219-2-3p down-regulated group than up-regulated group. CONCLUSIONS: miR-219-2-3p is potentially involved in gastric cancer progression and metastasis by regulating ERK1/2-related signal pathways, which may provide a novel therapeutic strategy

  3. Te-free environmental materials of TixSb2.19Se applied in phase change memory

    Science.gov (United States)

    Zhu, Yueqin; Song, Sannian; Li, Le; Xie, Huaqing; Song, Zhitang; Liu, Bo; Wu, Junxing

    2016-10-01

    Environmental friendly Te-free phase change material of TixSb2.19Se was investigated for PCM application. As the important thermal properties, the crystallization temperature (Tc) and data retention for ten years for the best selected composition Ti0.34Sb2.19Se (TSS) are 234°C and 160‡C, respectively. Detection of the crystal structure of TSS by means of XRD, TEM and XPS reveals that the grains are more uniform compared with Ge2Sb2Te5 (GST). The Set and Reset operation voltages for TSS-based phase change memory devices are much lower than those of conventional GST-based ones. Remarkably, the TSS device exhibits an extremely high phase change speed of 10 ns.

  4. Germination Response of MR 219 Rice Variety to Different Exposure Times and Periods of 2450 MHz Microwave Frequency

    OpenAIRE

    Daryush Talei; Alireza Valdiani; Mahmood Maziah; Mohammad Mohsenkhah

    2013-01-01

    Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR), germination percentage (GP), and mean germination time (MGT) were analyzed by exposing its seeds to 2450 MHz of microwave frequenc...

  5. {sup 18}F-labeling and biodistribution of the novel fluoro-quinolone antimicrobial agent, trovafloxacin (CP 99,219)

    Energy Technology Data Exchange (ETDEWEB)

    Babich, John W.; Rubin, Robert H.; Graham, Wendy A.; Wilkinson, Robert A.; Vincent, John; Fischman, Alan J

    1996-11-01

    [{sup 18}F]CP 99,219 [(1{alpha},5{alpha},6{alpha})-7-(6-amino-3-azabicyclo [3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid] was prepared by {sup 18}F for {sup 19} exchange followed by reverse-phase HPLC purification. Studies of the effects of reaction time and temperature on {sup 18}F incorporation demonstrated that heating 1.0 mg of CP 99,219 in 0.5 cc of DMSO with 4.5 mg of K{sub 2}CO{sub 3} and 24 mg of Kryptofix for 15 min at 160 deg. C results in the optimal compromise between radiochemical yield and purity. This method routinely provides radiochemical yields of 15-30% [EOS] with radiochemical purities of >97%. Varying the concentration of CP 99,219 in the reaction mixture had no effect on yield. Biodistribution studies in rats demonstrated that significant concentrations of drug accumulate in most tissues. The tissues with the highest concentrations of drug were intestine, liver, kidney, and stomach.

  6. Incidence and predictors of difficult laryngoscopy in 11,219 pediatric anesthesia procedures.

    Science.gov (United States)

    Heinrich, Sebastian; Birkholz, Torsten; Ihmsen, Harald; Irouschek, Andrea; Ackermann, Andreas; Schmidt, Joachim

    2012-08-01

    Difficult laryngoscopy in pediatric patients undergoing anesthesia. This retrospective analysis was conducted to investigate incidence and predictors of difficult laryngoscopy in a large cohort of pediatric patients receiving general anesthesia with endotracheal intubation. Young age and craniofacial dysmorphy are predictors for the difficult pediatric airway and difficult laryngoscopy. For difficult laryngoscopy, other general predictors are not yet described. Retrospectively, from a 5-year period, data from 11.219 general anesthesia procedures in pediatric patients with endotracheal intubation using age-adapted Macintosh blades in a single center (university hospital) were analyzed statistically. The overall incidence of difficult laryngoscopy [Cormack and Lehane (CML) grade III and IV] was 1.35%. In patients younger than 1 year, the incidence of CML III or IV was significantly higher than in the older patients (4.7% vs 0.7%). ASA Physical Status III and IV, a higher Mallampati Score (III and IV) and a low BMI were all associated (P < 0.05) with difficult laryngoscopy. Patients undergoing oromaxillofacial surgery and cardiac surgery showed a significantly higher rate of CML III/IV findings. The general incidence of difficult laryngoscopy in pediatric anesthesia is lower than in adults. Our results show that the risk of difficult laryngoscopy is much higher in patients below 1 year of age, in underweight patients and in ASA III and IV patients. The underlying disease might also contribute to the risk. If the Mallampati score could be obtained, prediction of difficult laryngoscopy seems to be reliable. Our data support the existing recommendations for a specialized anesthesiological team to provide safe anesthesia for infants and neonates. © 2012 Blackwell Publishing Ltd.

  7. INFERIOR TURBINECTOMY FOR NASAL OBSTRUCTION-STUDY O F 219 CASES

    Directory of Open Access Journals (Sweden)

    Santhosh

    2013-03-01

    Full Text Available ABSTRACT: OBJECTIVE : To determine the success rate of inferior turbine ctomy for nasal obstruction. To study complications of inferior turb inectomy. To study the histopathological changes in the inferior turbinate specimens. METHOD : This prospective, single blinded, randomized study of 219 consecutive patients carried out in two tertiary le vel centres from January 2010 to October 2011. The patients were asse ssed preoperatively and postoperatively both subjectively and objectively. The patients who were refractory to the directed conservative treatment for chronic nasal obstruction underwent i nferior turbinectomy on both sides and septoplasty if required. The inferior turbinectomy spe cimen was sent for histopathological examination. NOSE Questionnaires were used for subj ective assessment and rigid nasal endoscopy used for objective assessment. Follow up do ne at 1 week, 1 month and 6 months after surgery. Friedman test applied for assessment o f the improvement. RESULTS : 92 % (n=203 of patients relieved of nasal obstruction fo r which they approached. The improvement is statistically significant both subjectively and objectively. The common complications in present study is postoperative nasal synechia which o ccurred in 5% (n=10. Bleeding occurred in 4%(n=8. Dryness and crusting occurred in 2%(n=4 and foul odour in 2% (n=4. The present study also showed that most common cause for turbinate enlargement is chronic nonspecific inflammatory hypertrophy followed by aller gic turbinate hypertrophy. CONCLUSION : -The results show that inferior turbinectomy is t he good method of achieving relief from the nasal obstruction with minimal morb idity. Histopathological examination showed that most common cause of turbinate enlargem ent is chronic non specific turbinate hypertrophy and it proves beyond doubt that unnecessa ry excessive antiallergic treatment should be avoided in patients with chronic nasal obs truction KEY WORDS: inferior

  8. Association between apolipoprotein E promoter-219G/T polymorphism and total cholesterol level in patients with Alzheimer disease

    Institute of Scientific and Technical Information of China (English)

    Fang Liu; Xiao Sun; Jing Wang; Yan Kong; Li Cui; Xiangdang Shi

    2006-01-01

    BACKGROUND: Many researches have suggested that apolipoprotein E (APOE) and total cholesterol metabolism are closely related with dementia. In the supposed theory, 219 site of APOE promoter region is near gene coding region, so its polymorphism may result in the abnormality of APOE gene and protein expression,and finally lead to dementia.OBJECTIVE: To observe the association between APOE promoter-219G/T polymorphisms with serum total cholesterol in patients with Alzheimer disease, and compare it with non-dementia people.DESIGN: Case-control, comparative observation.SETTING: Department of Neurology, Fengtian Hospital of Shenyang Medical College.PARTICIPANTS: Fifty-five dementia patients including 27 males and 28 females aged (66±3) years and treated in the Department of Neurology, Fengtian Hospital were selected from January 2002 to December 2005 as the Alzheimer disease group. They all diagnosed according to the DSM- Ⅳ diagnostic criteria of Alzheimer disease instituted by American Psychiatry Association in 1994. Meanwhile, 44 none-dementia patients including 21 males and 23 females aged (66±3) years were selected from other clinical departments of Fengtian Hospital as control group. All the participants were informed the detection and agreed.METHODS: Genomic DNA was extracted from the peripheral blood of all subjects, then "NEST"PCR, DNA sequence and enzyme digestion were adopted to detect the expression of APOE promoter-219 polymorphism,following by biomedical statistics analysis based on the clinical total cholesterol level.MAIN OUTCOME MEASURES: Polymorphism of APOEpromoter-219 G/T and total cholesterol level.RESULTS: All 55 dementia patients and 44 non-dementia ones were involved in the result analysis. ①Allele and genotype frequency: The T allele frequency of the Alzheimer disease group was significantly higher than that in the control group [88.2% (97/110), 54.5% (48/88)], while G allele frequency was remarkably lower than that in the control group [11

  9. Amylose Content and Grain Length of New Rice Transgressive Variants Derived from a Cross Between O. rufipogon and Malaysian Rice Cultivar MR219

    Directory of Open Access Journals (Sweden)

    Parviz Fasahat

    2012-01-01

    Full Text Available Amylose content is one of the important grain quality properties of rice. A total of 10 new rice genotypes (BC2F7 generation derived from a cross between O. rufipogon Griff. accession IRGC105491 and O. sativa subspecies indica cv. MR219 with high yield were evaluated for amylose content in three environments in Peninsular Malaysia. One of the parents, a popular high yielding Malaysian rice cultivar MR219 was used as a check. Based on the average amylose content across the environments, the genotype G13 showed significantly (p < 0.05 different amylose content (23.88 % in comparison to other genotypes. Two genotypes G13 (25.7% and G15 (25.6% were higher than MR219 (25.1% in terms of amylose content in Sungai Besar environment. There was a positive (r2=0.018 but no significant correlation between amylose content and grain length.

  10. The beneficial endophyte Trichoderma hamatum isolate DIS 219b promotes growth and delays the onset of the drought response in Theobroma cacao.

    Science.gov (United States)

    Bae, Hanhong; Sicher, Richard C; Kim, Moon S; Kim, Soo-Hyung; Strem, Mary D; Melnick, Rachel L; Bailey, Bryan A

    2009-01-01

    Theobroma cacao (cacao) is cultivated in tropical climates and is exposed to drought stress. The impact of the endophytic fungus Trichoderma hamatum isolate DIS 219b on cacao's response to drought was studied. Colonization by DIS 219b delayed drought-induced changes in stomatal conductance, net photosynthesis, and green fluorescence emissions. The altered expression of 19 expressed sequence tags (ESTs) (seven in leaves and 17 in roots with some overlap) by drought was detected using quantitative real-time reverse transcription PCR. Roots tended to respond earlier to drought than leaves, with the drought-induced changes in expression of seven ESTs being observed after 7 d of withholding water. Changes in gene expression in leaves were not observed until after 10 d of withholding water. DIS 219b colonization delayed the drought-altered expression of all seven ESTs responsive to drought in leaves by > or = 3 d, but had less influence on the expression pattern of the drought-responsive ESTs in roots. DIS 219b colonization had minimal direct influence on the expression of drought-responsive ESTs in 32-d-old seedlings. By contrast, DIS 219b colonization of 9-d-old seedlings altered expression of drought-responsive ESTs, sometimes in patterns opposite of that observed in response to drought. Drought induced an increase in the concentration of many amino acids in cacao leaves, while DIS 219b colonization caused a decrease in aspartic acid and glutamic acid concentrations and an increase in alanine and gamma-aminobutyric acid concentrations. With or without exposure to drought conditions, colonization by DIS 219b promoted seedling growth, the most consistent effects being an increase in root fresh weight, root dry weight, and root water content. Colonized seedlings were slower to wilt in response to drought as measured by a decrease in the leaf angle drop. The primary direct effect of DIS 219b colonization was promotion of root growth, regardless of water status, and an

  11. 2,19-二十二酮的新合成方法%A novel synthesis of long-chained acyclic diketone 2, 19-eicosanedione

    Institute of Scientific and Technical Information of China (English)

    吴新亮; 郭媛; 张斌; 史真

    2005-01-01

    以邻苯二胺和1,18-十八二酸为原料,经二苯并咪唑盐与格利雅试剂的加成-水解反应,合成出了长链二酮--2,19-二十二酮.同时,研究了合成2,19-二十二酮的最佳反应条件,并对其反应机理进行了讨论.

  12. miR-219基因及其靶基因CAMK2G多态性与精神分裂症的关联研究%Association study of the polymorphisms in miR-219 gene and its target gene CAMK2G with schizophrenia

    Institute of Scientific and Technical Information of China (English)

    张燕霞; 汪栋祥; 李华芳; 傅迎美; 禹顺英

    2013-01-01

    Objectives This study aims to determine the potential association between polymorphisms in miR-219 gene and its target gene CAMK2G and schizophrenia. Methods Two SNPs (rs 107822 in miR-219 and rs2306327 in CAMK2G)were selected and genotyped by the TaqMan genotyping assay in a case-control study with 1041 schizophrenia cases and 953 healthy controls in Chinese Han population. Secondary structure of miR-219 with rs 107822 was constructed via the CentroidFold software. Results The allele frequency distribution of rs 107822 was statistically different between schizophrenia and healthy controls (χ2=7.33, P=0.007). Logistic regression analyses showed that the additive inheritance model was the best model for the gennotyping data of rs 107822 (P=0.0072). Individuals who carried the C allele were associated with significantly decreased risk of developing schizophrenia (OR=0.84, 95 % CI=0.74~ 0.95). Structure prediction by software found that secondary structure of miR-219 primary trancript (pri-miR-219) was changed when the T allele at rs 107822 was mutated to Callele. No statistical difference was found between cases and controls with regard to the allele or genotype distribution of rs2306327 .Conclusions These findings suggest that polymorphism rs l07822 in miR-219 gene may be associated with schizophrenia in the Chinese Han population.%目的 探讨微小核糖核苷酸-219(microRNA-219,miR-219)及其靶基因钙离子/钙调蛋白依赖性蛋白激酶Ⅱγ(Ca2+/calmodulin-dependent protein kinase Ⅱ gamma,CAMK2G)多态性与精神分裂症的关系. 方法 采用TaqMan探针基因分型技术在中国汉族人群中对1041例精神分裂症患者和953例正常对照者进行miR-219基因rs107822和CAMK2G基因rs2306327的分型.利用二级结构预测软件CentroidFold预测rs107822对miR-219二级结构影响.结果 miR-219基因rs107822多态的等位基因分布在患者组与正常对照组之间差异有统计学意义(x2=7.33,P=0.007);

  13. Comparative in vitro activities of trovafloxacin (CP-99,219) against 445 gram-positive isolates from patients with endocarditis and those with other bloodstream infections

    NARCIS (Netherlands)

    H.P. Endtz (Hubert); J.W. Mouton (Johan); J.G. den Hollander (Jan); N.P.W.C.J. van den Braak (Nicole); H.A. Verbrugh (Henri)

    1997-01-01

    textabstractThe in vitro activity of trovafloxacin (CP-99,219), a new fluoroquinolone, was compared with the in vitro activities of other commonly used quinolones and other antimicrobial agents against 445 gram-positive microorganisms isolated between 1986 and 1995 from

  14. 48 CFR 653.219-70 - DOS form DS-1910, Small Business Agency Review-Actions Above the Simplified Acquisition Threshold.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false DOS form DS-1910, Small... 653.219-70 DOS form DS-1910, Small Business Agency Review—Actions Above the Simplified Acquisition Threshold. As prescribed in 619.501(c), DS-1910 is prescribed for use in documenting set-aside decisions. ...

  15. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false DOS form DS-4053... Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i), DS-4053...

  16. Erratum to: "A note on the preconditioned Gauss-Seidel method for M-matrices" [J. Comput. Appl. Math. 219 (1) (2008) 59-71

    Science.gov (United States)

    Liu, Qingbing; Chen, Guoliang

    2009-06-01

    In this note, some errors in a recent article by Niki et al. [H. Niki, T. Kohno, M. Morimoto, The preconditioned Gauss-Seidel method faster than the SOR method, J. Comput. Appl. Math. 219 (2008) 59-71] are pointed out and a new proof for the corresponding result is presented.

  17. Investigation and analysis on occupational impairment state in 219 firemen%某市219名消防员职业损伤情况调查分析

    Institute of Scientific and Technical Information of China (English)

    牛素玲

    2011-01-01

    目的 了解消防员职业损伤情况及其影响因素,为完善防护措施提供依据.方法 采用访谈、座谈和问卷调查等方法,对某市3个消防中队共219名消防员进行调查.结果 消防员存在训练致伤、火场致伤、装备因素致伤和心理应激等4大类职业损伤,问题较为突出的是训练伤中的腿部拉伤和警铃刺激致心理紧张,分别占调查总人数的55.7%和64.2%.3队之间职业损伤率存在一定差异(P<0.05),医学知识培训可减少消防员职业损伤.结论 科学进行消防员的专业训练,科学配置个体防护装备,建立医学知识培训制度,定期进行消防员的医学知识培训和职业健康监护,有助于减少消防员职业损伤.%Objective To understand the current status of occupational injuries of firefighters and its influencing factors, in order to provide reference for improving the protection measures. Methods 219 firefighter respondents from 3 fire departments in a certain city were investigated by in-depth interviews, group discussions and survey questionnaires. Results Based on the cause of injury, the injuries of firefighters could be categorized into 4 groups: training injuries, firefighting injuries, equipment-caused injuries and mental stress groups. Calf muscle strain of training injuries and psychological stress caused by alarm bell were two most outstanding problems, accounting for 55.7% and 64.2% respectively. Statistical significant differences were found among 3 teams (P < 0.05). Basic medical training was helpful to reduce and prevent occupational injuries. Conclusion To help reduce the occupational injuries for firefighters, much more efforts should be devoted take scientific training me-thods, to configure individual protective equipment, to establish medical knowledge training system and to take regular occupational health surveillance for them.

  18. Immunophenotypes and Cytogenetic Alterations in 219 Cases of Diffuse Large B-cell Lymphoma%219例弥漫性大B 细胞淋巴瘤免疫表型及遗传学特征分析

    Institute of Scientific and Technical Information of China (English)

    管冰心; 潘毅; 房爱菊; 梁艳; 霍颖颖; 孙保存; 王华庆; 付凯; 孟斌

    2012-01-01

    Objective: To investigate the immunophenotypes, subtypes based on Hans algorithm, and alterations of Bcl-2 and Bcl-6 gene in diffuse large B-cell lymphoma ( DLBCL) from Chinese patients. Methods: The expression of CD10, BCL-6, MUM1, BCL-2, Ki67 and other markers were detected by immunohistochemistry in tissue microarrays of 219 DLBCL cases. Hans algorithm was applied to classify DLBCL into GCB and non-GCB subtypes. Interphase fluorescence in situ hybridization ( FISH ) was used to detect the incidence of Bcl-2 and Bcl-6 gene alterations. Other seven studies published in the last two years on DLBCL from China were collected and analyzed. Results: (1) This study: ① of 219 DLBCL cases, non-GCB subtype ( 165 cases, 75.3 % ) was significantly more common than GCB subtype ( 54 cases, 24.7 %)(P< 0.001). ② Bcl-2 gene alteration was detected in 49 cases (25.8 %), including 5 cases with the t (14 ; 18) (2.6 %) which all existed in GCB subtype, and 44 cases of Bcl-2 amplification ( 23.2 % ) which existed in GCB subtype in 4 cases ( 8.5 % ) and in non-GCB subtype in 40 cases (28.0 %){P = 0.013). ③ Bcl-6 gene rearrangement was detected in 42 cases (22.1 %), which was in GCB in 7 cases (14.9 % ) and was in non-GCB in 35 cases (24.5 % ) (P = 0.189). ④ a significant negative correlation between Bcl-2 gene amplification and Bcl-6 gene rearrangement was seen (r = - 0.179 6, P = 0.016 8). Amongst 5 cases having the t (14 ; 18) translocation, 2 cases accompanied by Bcl-6 gene rearrangement. Forty-nine cases with Bcl-2 gene alterations including translocation and amplification were all but one expressing BCL-2 protein, and there was no significant association between Bcl-6 gene rearrangement and BCL-6 protein expression ( P = 0.726 ). ⑤ there was no significant difference between nodal and extranodal DLBCLs in immunophenotypes, subtypes based on Hans algorithm, and Bcl-2 and Bcl-6 gene alterations (P = 0.462, P = 0.426 and P = 0.167). (2) Comprehensive analysis of eight

  19. 微小RNA-219-5p在肝细胞肝癌中的表达及其与乙醇的关系%Expression of microRNA-219-5p in hepatocellular carcinoma and its relationship with alcohol

    Institute of Scientific and Technical Information of China (English)

    李辉; 曹会存; 刘诗义; 刘健; 曹广劭; 赵晓阳

    2015-01-01

    Objective To study the roles of microRNA (miRNA,miR)-219-5p in the pathogenesis of hepatocellular carcinoma (HCC) and its relationship with alcohol and clinicopathological features.Methods The expression of miR-219-5p in 120 cases of HCC tissue samples was detected by real-time fluorescent quantitative polymerase chain reaction (FQ-PCR),and its relationship with alcohol and clinicopathological features was analyzed.Results (1) The expression of miR-219-5p was decreased significantly in those cancers tumors with diameter > 5 cm,worse tissue differentiation and heavy drinking (x2 =10.550,3.956,and 6.061 respectively,P < 0.01);(2) The logistic regression analysis revealed thaat a history of heavy drinking was one of the major risk factors of down-regulated miR-219-5p expression level [95% confidence interval (CI):1.521-17.635,P <0.05);(3) In the Cox regression model,the patients with the down-regulated miR-219-5p expression levels had high risk of death,and drinking,positive alpha fetal protein (AFP),chronic liver disease and larger tumor further increased the risk for death (P < 0.05).Conclusion It is believed that the expression of miR-219-5p,serum AFP-positive,tumor size,and chronic liver disease are independent risk factors for survival of patients with HCC,while heavy drinking consumption can further amplify the effects.%目的 观察微小RNA(miRNA,miR)-219-5p与乙醇、临床病理特征的关系及其在肝细胞肝癌(HCC)发生发展中的作用.方法 采用实时荧光定量聚合酶链反应(FQ-PCR)法对120例HCC患者组织中的miR-219-5p的表达进行检测,并比较其与饮酒、临床病理特征之间关系.结果 (1)肿瘤瘤体>5 cm、组织分化差以及大量饮酒者miR-219-5p的表达显著降低(x2=10.550、3.956、6.061,P<0.05);(2)在Logistic回归分析中,大量饮酒史是miR-219-5p表达水平下降的主要危险因素之一[95%可信区间(CI):1.521 ~ 17.635,P<0.05];(3)在Cox回归模型中,miR-219-5p表达水

  20. Germination response of MR 219 rice variety to different exposure times and periods of 2450 MHz microwave frequency.

    Science.gov (United States)

    Talei, Daryush; Valdiani, Alireza; Maziah, Mahmood; Mohsenkhah, Mohammad

    2013-01-01

    Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR), germination percentage (GP), and mean germination time (MGT) were analyzed by exposing its seeds to 2450 MHz of microwave frequency for one, four, seven, and ten hours. It was revealed that exposing the seeds to the microwave frequency for 10 hours resulted in the highest GP. This treatment led to 100% of germination after three days with a mean germination time of 2.1 days. Although the other exposure times of microwave frequency caused the moderate effects on germination with a GP(a3) ranged from 93% to 98%, they failed to reduce the MGT(a3). The results showed that ten-hour exposure times of microwave frequency for six days significantly facilitated and improved the germination indices (primary shoot and root length). Therefore, the technique is expected to benefit the improvement of rice seed germination considering its simplicity and efficacy in increasing the germination percentage and rate as well as the primary shoot and root length without causing any environmental toxicity.

  1. Germination Response of MR 219 Rice Variety to Different Exposure Times and Periods of 2450 MHz Microwave Frequency

    Directory of Open Access Journals (Sweden)

    Daryush Talei

    2013-01-01

    Full Text Available Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR, germination percentage (GP, and mean germination time (MGT were analyzed by exposing its seeds to 2450 MHz of microwave frequency for one, four, seven, and ten hours. It was revealed that exposing the seeds to the microwave frequency for 10 hours resulted in the highest GP. This treatment led to 100% of germination after three days with a mean germination time of 2.1 days. Although the other exposure times of microwave frequency caused the moderate effects on germination with a GPa3 ranged from 93% to 98%, they failed to reduce the MGTa3. The results showed that ten-hour exposure times of microwave frequency for six days significantly facilitated and improved the germination indices (primary shoot and root length. Therefore, the technique is expected to benefit the improvement of rice seed germination considering its simplicity and efficacy in increasing the germination percentage and rate as well as the primary shoot and root length without causing any environmental toxicity.

  2. Outbreak of drug-resistant Acinetobacter baumannii ST219 caused by oral care using tap water from contaminated hand hygiene sinks as a reservoir.

    Science.gov (United States)

    Umezawa, Kazuo; Asai, Satomi; Ohshima, Toshio; Iwashita, Hideo; Ohashi, Maya; Sasaki, Mika; Kaneko, Akihiro; Inokuchi, Sadaki; Miyachi, Hayato

    2015-11-01

    An outbreak of amikacin- and ciprofloxacin-resistant Acinetobacter baumannii ST219 in Tokai University hospital's emergency intensive care unit was caused by its colonization in water systems and subsequent spread through oral care using tap water. The outbreak was successfully controlled after replacement of the water system and implementation as of daily cleaning of water taps and oral care with a dry method. It is important to strictly manage the water system in critical care areas.

  3. Infection of domestic dogs in peru by zoonotic bartonella species: a cross-sectional prevalence study of 219 asymptomatic dogs.

    Directory of Open Access Journals (Sweden)

    Pedro Paulo V P Diniz

    Full Text Available Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to infect humans, with eight of these capable of infecting dogs as well. B. bacilliformis is the only species described infecting humans in Peru; however, several other Bartonella species were detected in small mammals, bats, ticks, and fleas in that country. The objective of this study was to determine the serological and/or molecular prevalence of Bartonella species in asymptomatic dogs in Peru in order to indirectly evaluate the potential for human exposure to zoonotic Bartonella species. A convenient sample of 219 healthy dogs was obtained from five cities and three villages in Peru. EDTA-blood samples were collected from 205 dogs, whereas serum samples were available from 108 dogs. The EDTA-blood samples were screened by PCR followed by nucleotide sequencing for species identification. Antibodies against B. vinsonii berkhoffii and B. rochalimae were detected by IFA (cut-off of 1∶64. Bartonella DNA was detected in 21 of the 205 dogs (10%. Fifteen dogs were infected with B. rochalimae, while six dogs were infected with B. v. berkhoffii genotype III. Seropositivity for B. rochalimae was detected in 67 dogs (62%, and for B. v. berkhoffii in 43 (40% of the 108 dogs. Reciprocal titers ≥1∶256 for B. rochalimae were detected in 19% of dogs, and for B. v. berkhoffii in 6.5% of dogs. This study identifies for the first time a population of dogs exposed to or infected with zoonotic Bartonella species, suggesting that domestic dogs may be the natural reservoir of these zoonotic organisms. Since dogs are epidemiological sentinels, Peruvian humans may be exposed to infections with B. rochalimae or B. v. berkhoffii.

  4. Infection of domestic dogs in peru by zoonotic bartonella species: a cross-sectional prevalence study of 219 asymptomatic dogs.

    Science.gov (United States)

    Diniz, Pedro Paulo V P; Morton, Bridget A; Tngrian, Maryam; Kachani, Malika; Barrón, Eduardo A; Gavidia, Cesar M; Gilman, Robert H; Angulo, Noelia P; Brenner, Elliott C; Lerner, Richard; Chomel, Bruno B

    2013-01-01

    Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to infect humans, with eight of these capable of infecting dogs as well. B. bacilliformis is the only species described infecting humans in Peru; however, several other Bartonella species were detected in small mammals, bats, ticks, and fleas in that country. The objective of this study was to determine the serological and/or molecular prevalence of Bartonella species in asymptomatic dogs in Peru in order to indirectly evaluate the potential for human exposure to zoonotic Bartonella species. A convenient sample of 219 healthy dogs was obtained from five cities and three villages in Peru. EDTA-blood samples were collected from 205 dogs, whereas serum samples were available from 108 dogs. The EDTA-blood samples were screened by PCR followed by nucleotide sequencing for species identification. Antibodies against B. vinsonii berkhoffii and B. rochalimae were detected by IFA (cut-off of 1∶64). Bartonella DNA was detected in 21 of the 205 dogs (10%). Fifteen dogs were infected with B. rochalimae, while six dogs were infected with B. v. berkhoffii genotype III. Seropositivity for B. rochalimae was detected in 67 dogs (62%), and for B. v. berkhoffii in 43 (40%) of the 108 dogs. Reciprocal titers ≥1∶256 for B. rochalimae were detected in 19% of dogs, and for B. v. berkhoffii in 6.5% of dogs. This study identifies for the first time a population of dogs exposed to or infected with zoonotic Bartonella species, suggesting that domestic dogs may be the natural reservoir of these zoonotic organisms. Since dogs are epidemiological sentinels, Peruvian humans may be exposed to infections with B. rochalimae or B. v. berkhoffii.

  5. Cyto-histological correlation of 219 patients submitted to surgical treatment due to diagnosis of cervical intraepithelial neoplasia

    Directory of Open Access Journals (Sweden)

    Sheila Jorge Adad

    1999-03-01

    Full Text Available CONTEXT: Cervical cytology continues to be the most appropriate method for investigating cervical neoplasia and its precursors. Greater diagnostic acuity is obtained by combining cytology, colposcopy and guided biopsy methods. OBJECTIVE: To analyze the diagnostic acuity of cyto- and histopathological exams and causes of diagnostic error. DESIGN: Retrospective study. SETTING: A public tertiary referral center. SAMPLE: Reports on 219 patients submitted to cone biopsy and/or hysterectomy due to diagnosis of cervical intraepithelial neoplasia (CIN in the period between January 1982 and March 1997 were reviewed, comparing. MAIN MEASUREMENTS: cytological and histological exams (guided biopsy and surgically-removed tissue. In cases of discordance, the cyto- and histological preparations were reviewed to try to evaluate the causes of errors. RESULTS: In 193 cases (88.1% there was cyto-histological agreement but none in 26 (11.9%. Review of the discordant cases showed that in 2 (0.9% there was invasion of the stromata to a depth greater than 3mm, and in 7 (3.2% microinvasion, unsuspected via cytology; in 2 (0.9% microinvasion was suspected via cytology but not confirmed by the final histological exam; and in 15 (6.8% there was disagreement about the degree of CIN. CONCLUSION: The principal causes of error in the cytological exam were the lack of reliable morphological criteria for microinvasion, absence of sampling of the squamocolumnar junction, and scarcity of neoplastic cells in the sample. As for the histological exam, the errors were related to inadequate technical processing and underestimation of focal lesions.

  6. 76 FR 70336 - Airworthiness Directives; Rolls-Royce plc RB211-524G2-19; -524G2-T-19; -524G3-19; -524G3-T-19...

    Science.gov (United States)

    2011-11-14

    ... plc RB211-524G2-19; -524G2- T-19; -524G3-19; -524G3-T-19; 524H2-19; -524H2-T-19; -524H-36; and - 524H..., 2011. The Director of the Federal Register approved the incorporation by reference of Rolls-Royce plc... Information Rolls-Royce plc has issued Rolls-Royce plc Alert Service Bulletin No. RB.211-73-AG054, Revision...

  7. Corrective Action Investigation Plan for Corrective Action Unit 219: Septic Systems and Injection Wells, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    David A. Strand

    2005-01-01

    The Corrective Action Investigation Plan for Corrective Action Unit 219, Septic Systems and Injection Wells, has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy, and the U.S. Department of Defense. The purpose of the investigation is to ensure that adequate data are collected to provide sufficient and reliable information to identify, evaluate, and select technically viable corrective actions. Corrective Action Unit 219 is located in Areas 3, 16, and 23 of the Nevada Test Site, which is 65 miles northwest of Las Vegas, Nevada. Corrective Action Unit 219 is comprised of the six Corrective Action Sites (CASs) listed below: (1) 03-11-01, Steam Pipes and Asbestos Tiles; (2) 16-04-01, Septic Tanks (3); (3) 16-04-02, Distribution Box; (4) 16-04-03, Sewer Pipes; (5) 23-20-01, DNA Motor Pool Sewage and Waste System; and (6) 23-20-02, Injection Well. These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives. Additional information will be obtained by conducting a corrective action investigation prior to evaluating corrective action alternatives and selecting the appropriate corrective action for each CAS. The results of the field investigation will support a defensible evaluation of viable corrective action alternatives that will be presented in the Corrective Action Decision Document.

  8. Dynamical decay process of {sup 219,} {sup 220}Ra{sup *} formed in {sup 10,} {sup 11}B+{sup 209}Bi reactions

    Energy Technology Data Exchange (ETDEWEB)

    Sawhney, G.; Sharma, M.K. [Thapar University, School of Physics and Materials Science, Punjab (India)

    2012-05-15

    The excitation functions for both the evaporation residue and fission have been calculated for {sup 10}B +{sup 209}Bi and {sup 11}B+{sup 209}Bi reactions forming compound systems {sup 219,220}Ra{sup *}, using the dynamical cluster-decay model (DCM) with effects of deformations and orientations of the nuclei included in it. In addition to this, the excitation functions for complete fusion (CF) are obtained by summing the fission cross-sections, neutron evaporation and charged particle evaporation residue cross-sections produced through the {alpha}xn and pxn (x = 2, 3, 4) emission channels for the {sup 219}Ra system at various incident centre-of-mass energies. Experimentally the CF cross-sections are suppressed and the observed suppression is attributed to the low binding energy of {sup 10,11}B which breaks up into charged fragments. The reported complete fusion (CF) and incomplete fusion (ICF) excitation functions for the {sup 219}Ra system are found to be nicely fitted by the calculations performed in the framework of DCM, without invoking a significant contribution from quasi-fission. Although DCM has been applied for a number of compound nucleus decay studies in the recent past, the same is being used here in reference to ICF and subsequent decay processes along with the CF process. Interestingly the main contribution to complete fusion cross-section comes from the fission cross-section at higher incident energies, which in DCM is found to consist of an asymmetric fission window, shown to arise due to the deformation and orientation effects of formation and decay fragments. (orig.)

  9. Production of actinium-225 for alpha particle mediated radioimmunotherapy.

    Science.gov (United States)

    Boll, Rose A; Malkemus, Dairin; Mirzadeh, Saed

    2005-05-01

    The initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the alpha emitter (213)Bi in killing cancer cells. Bismuth-213 is obtained from a radionuclide generator system from decay of 10-days (225)Ac parent. Recent pre-clinical studies have also shown the potential application of both (213)Bi, and the (225)Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy. This paper describes our five years of experience in production of (225)Ac in partial support of the on-going clinical trials. A four-step chemical process, consisting of both anion and cation exchange chromatography, is utilized for routine separation of carrier-free (225)Ac from a mixture of (228)Th, (229)Th and (232)Th. The separation of Ra and Ac from Th is achieved using the marcoporous anion exchange resin MP1 in 8M HNO(3) media. Two sequential MP1/NO(3) columns provide a separation factor of approximately 10(6) for Ra and Ac from Th. The separation of Ac from Ra is accomplished on a low cross-linking cation exchange resin AG50-X4 using 1.2M HNO(3) as eluant. Two sequential AG50/NO(3) columns provide a separation factor of approximately 10(2) for Ac from Ra. A 60-day processing schedule has been adopted in order to reduce the processing cost and to provide the highest levels of (225)Ac possible. Over an 8-week campaign, a total of approximately 100 mCi of (225)Ac (approximately 80% of the theoretical yield) is shipped in 5-6 batches, with the first batch typically consisting of approximately 50 mCi. After the initial separation and purification of Ac, the Ra pool is re-processed on a bi-weekly schedule or as needed to provide smaller batches of (225)Ac. The averaged radioisotopic purity of the (225)Ac was 99.6 +/- 0.7% with a (225)Ra content of < or =0.6%, and an average (229)Th content of (4(-4)(+5)) x 10(-5)%.

  10. Isolation of Actinium from Neutron-irradiated Thorium-I

    Institute of Scientific and Technical Information of China (English)

    1994-01-01

    Isolation of Actinium from Neutron-irradiated Thorium-I¥YangWeifan;YuanShuanggui;MuWantong;ZhangXueqian;LiZhongweiandZhaoLili...

  11. Characterization of the K2-19 Multiple-Transiting Planetary System via High-Dispersion Spectroscopy, AO Imaging, and Transit Timing Variations

    CERN Document Server

    Narita, Norio; Fukui, Akihiko; Hori, Yasunori; Sanchis-Ojeda, Roberto; Winn, Joshua N; Ryu, Tsuguru; Kusakabe, Nobuhiko; Kudo, Tomoyuki; Onitsuka, Masahiro; Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel; McCormac, James; Holman, Matthew; Izumiura, Hideyuki; Takeda, Yoichi; Tamura, Motohide; Yanagisawa, Kenshi

    2015-01-01

    K2-19 (EPIC201505350) is a unique planetary system in which two transiting planets with radii ~ 7 $R_{Earth}$ (inner planet b) and ~ 4 $R_{Earth}$ (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2m telescope. We find that the host star is relatively old (>8 Gyr) late G-type star ($T_{eff}$ ~ 5350 K, $M_s$ ~ 0.9 $M_{Sun}$, and $R_{s}$ ~ 0.9 $R_{Sun}$). We do not find any contaminating faint objects near the host star which could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2m telescope, TRAPPISTCAM on the TRAPPIST 0.6m telescope, and MuSCAT on the OAO 1.88m telescope. We confirm the presence of transit-timing variations, as previously re...

  12. Corrective Action Decision Document/Closure Report for Corrective Action Unit 219: Septic Systems and Injection Wells, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    David Strand

    2006-05-01

    This Corrective Action Decision Document/Closure Report has been prepared for Corrective Action Unit (CAU) 219, Septic Systems and Injection Wells, in Areas 3, 16, and 23 of the Nevada Test Site, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit 219 is comprised of the following corrective action sites (CASs): (1) 03-11-01, Steam Pipes and Asbestos Tiles; (2) 16-04-01, Septic Tanks (3); (3) 16-04-02, Distribution Box; (4) 16-04-03, Sewer Pipes; (5) 23-20-01, DNA Motor Pool Sewage and Waste System; and (6) 23-20-02, Injection Well. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the recommendation for closure of CAU 219 with no further corrective action beyond the application of a use restriction at CASs 16-04-01, 16-04-02, and 16-04-03. To achieve this, corrective action investigation (CAI) activities were performed from June 20 through October 12, 2005, as set forth in the CAU 219 Corrective Action Investigation Plan and Record of Technical Change No. 1. A best management practice was implemented at CASs 16-04-01, 16-04-02, and 16-04-03, and corrective action was performed at CAS 23-20-01 between January and April 2006. In addition, a use restriction will be applied to CASs 16-04-01, 16-04-02, and 16-04-03 to provide additional protection to Nevada Test Site personnel. The purpose of the CAI was to fulfill the following data needs as defined during the data quality objective (DQO) process: (1) Determine whether contaminants of concern (COCs) are present. (2) If COCs are present, determine their nature and extent. (3) Provide sufficient information and data to complete appropriate corrective actions. The CAU 219 dataset from the investigation results was evaluated based on the data quality indicator parameters. This evaluation demonstrated the quality and acceptability of the dataset for use in fulfilling

  13. Leptin receptor isoform 219.1: an example of protein evolution by LINE-1-mediated human-specific retrotransposition of a coding SVA element.

    Science.gov (United States)

    Damert, Annette; Löwer, Johannes; Löwer, Roswitha

    2004-04-01

    Phylogenetically new insertions of repetitive sequences may contribute to genome evolution by altering the function of preexisting proteins. One example is the SVA sequence, which forms the C-terminal coding exon of the human leptin receptor isoform 219.1. Here, we report that the SVA insertion into the LEPR locus has occurred after divergence of humans and chimpanzees. The SVA element was inserted into a Hal-1/LINE element present in all monkeys and apes tested. Structural features point toward an integration event that was mediated by the L1 protein machinery acting in trans. Thus, our findings add evidence to the hypothesis that retrotransposition events are a driving force in genomic evolution and that the presence or absence of specific retroelements are one distinguishing feature that separates humans from chimpanzees.

  14. Determination of optimum welding parameters in connecting high alloyed X53CrMnNiN219 and X45CrSi93 steels by friction welding

    Indian Academy of Sciences (India)

    Mehmet Uzkut; Bekir Sadik Ünlü; Mustafa Akdağ

    2011-07-01

    In this study, different welding parameters were applied to two different steels with high alloys and mechanical and metallographical investigations are performed. Thus, the optimum welding parameters were determined for these materials and working conditions. 12.30 diameter steel bars made up of 1.4871 (X53CrMnNiN219) and 1.4718 (X45CrSi93) steel were used as experimental material. The material loss increased with increase in friction and rotating pressure. No fracture at the welding region was observed and the highest fracture energy was identified in B5 group. Based on micro hardness investigation; the hardness profile reached its minimum value at the welding region.

  15. Discovery of Eclipsing Binary Central Stars in the Planetary Nebulae M 3-16, H 2-29 and M 2-19

    CERN Document Server

    Miszalski, B; Moffat, A F J; Parker, Q A; Udalski, A

    2008-01-01

    Progress in understanding the formation and evolution of planetary nebulae (PN) has been restricted by a paucity of well-determined central star masses. To address this deficiency we aim to (i) significantly increase the number of known eclipsing binary central stars of PN (CSPN), and subsequently (ii) directly obtain their masses and absolute dimensions by combining their light-curve parameters with planned radial velocity data. Using photometric data from the third phase of the Optical Gravitational Lensing Experiment (OGLE) we have searched for periodic variability in a large sample of PN towards the Galactic Bulge using Fourier and phase-dispersion minimisation techniques. Among some dozen periodically variable CSPN found, we report here on three new eclipsing binaries: M 3-16, H 2-29 and M 2-19. We present images, confirmatory spectroscopy and light-curves of the systems.

  16. Transient climate simulations of the deglaciation 21-9 thousand years before present; PMIP4 Core experiment design and boundary conditions

    Science.gov (United States)

    Ivanovic, Ruza; Gregoire, Lauren; Kageyama, Masa; Roche, Didier; Valdes, Paul; Burke, Andrea; Drummond, Rosemarie; Peltier, W. Richard; Tarasov, Lev

    2016-04-01

    The last deglaciation, which marked the transition between the last glacial and present interglacial periods, was punctuated by a series of rapid (centennial and decadal) climate changes. Numerical climate models are useful for investigating mechanisms that underpin the events, especially now that some of the complex models can be run for multiple millennia. We have set up a Paleoclimate Modelling Intercomparison Project (PMIP) working group to coordinate efforts to run transient simulations of the last deglaciation, and to facilitate the dissemination of expertise between modellers and those engaged with reconstructing the climate of the last 21 thousand years. Here, we present the design of a coordinated Core simulation over the period 21-9 thousand years before present (ka) with time varying orbital forcing, greenhouse gases, ice sheets, and other geographical changes. A choice of two ice sheet reconstructions is given. Additional focussed simulations will also be coordinated on an ad-hoc basis by the working group, for example to investigate the effect of ice sheet and iceberg meltwater, and the uncertainty in other forcings. Some of these focussed simulations will concentrate on shorter durations around specific events to allow the more computationally expensive models to take part. Ivanovic, R. F., Gregoire, L. J., Kageyama, M., Roche, D. M., Valdes, P. J., Burke, A., Drummond, R., Peltier, W. R., and Tarasov, L.: Transient climate simulations of the deglaciation 21-9 thousand years before present; PMIP4 Core experiment design and boundary conditions, Geosci. Model Dev. Discuss., 8, 9045-9102, doi:10.5194/gmdd-8-9045-2015, 2015.

  17. Characterization of the K2-19 Multiple-transiting Planetary System via High-dispersion Spectroscopy, AO Imaging, and Transit Timing Variations

    Science.gov (United States)

    Narita, Norio; Hirano, Teruyuki; Fukui, Akihiko; Hori, Yasunori; Sanchis-Ojeda, Roberto; Winn, Joshua N.; Ryu, Tsuguru; Kusakabe, Nobuhiko; Kudo, Tomoyuki; Onitsuka, Masahiro; Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel; McCormac, James; Holman, Matthew; Izumiura, Hideyuki; Takeda, Yoichi; Tamura, Motohide; Yanagisawa, Kenshi

    2015-12-01

    K2-19 (EPIC201505350) is an interesting planetary system in which two transiting planets with radii ∼7 R⊕ (inner planet b) and ∼4 R⊕ (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2 m telescope. We find that the host star is a relatively old (≥8 Gyr) late G-type star (Teff ∼ 5350 K, Ms ∼ 0.9 M⊙, and Rs ∼ 0.9 R⊙). We do not find any contaminating faint objects near the host star that could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2 m telescope, TRAPPISTCAM on the TRAPPIST 0.6 m telescope, and MuSCAT on the OAO 1.88 m telescope. We confirm the presence of transit timing variations (TTVs), as previously reported by Armstrong and coworkers. We model the observed TTVs of the inner planet using the synodic chopping formulae given by Deck & Agol. We find two statistically indistinguishable solutions for which the period ratios (Pc/Pb) are located slightly above and below the exact 3:2 commensurability. Despite the degeneracy, we derive the orbital period of the inner planet Pb ∼ 7.921 days and the mass of the outer planet Mc ∼ 20 M⊕. Additional transit photometry (especially for the outer planet) as well as precise radial-velocity measurements would be helpful to break the degeneracy and to determine the mass of the inner planet.

  18. Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate.

    Science.gov (United States)

    Chen, Wen-Hsiang; Chag, Shivali M; Poongavanam, Mohan V; Biter, Amadeo B; Ewere, Ebe A; Rezende, Wanderson; Seid, Christopher A; Hudspeth, Elissa M; Pollet, Jeroen; McAtee, C Patrick; Strych, Ulrich; Bottazzi, Maria Elena; Hotez, Peter J

    2017-08-01

    From 2002 to 2003, a global pandemic of severe acute respiratory syndrome (SARS) spread to 5 continents and caused 8000 respiratory infections and 800 deaths. To ameliorate the effects of future outbreaks as well as to prepare for biodefense, a process for the production of a recombinant protein vaccine candidate is under development. Previously, we reported the 5 L scale expression and purification of a promising recombinant SARS vaccine candidate, RBD219-N1, the 218-amino acid residue receptor-binding domain (RBD) of SARS coronavirus expressed in yeast-Pichia pastoris X-33. When adjuvanted with aluminum hydroxide, this protein elicited high neutralizing antibody titers and high RBD-specific antibody titers. However, the yield of RBD219-N1 (60 mg RBD219-N1 per liter of fermentation supernatant; 60 mg/L FS) still required improvement to reach our target of >100 mg/L FS. In this study, we optimized the 10 L scale production process and increased the fermentation yield 6- to 7-fold to 400 mg/L FS with purification recovery >50%. A panel of characterization tests indicated that the process is reproducible and that the purified, tag-free RBD219-N1 protein has high purity and a well-defined structure and is therefore a suitable candidate for production under current Good Manufacturing Practice and future phase-1 clinical trials. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  19. CHARACTERIZATION OF THE K2-19 MULTIPLE-TRANSITING PLANETARY SYSTEM VIA HIGH-DISPERSION SPECTROSCOPY, AO IMAGING, AND TRANSIT TIMING VARIATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Narita, Norio; Hori, Yasunori; Kusakabe, Nobuhiko; Takeda, Yoichi; Tamura, Motohide [Astrobiology Center, 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Hirano, Teruyuki [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); Fukui, Akihiko; Yanagisawa, Kenshi [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asakuchi, Okayama 719-0232 (Japan); Sanchis-Ojeda, Roberto [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Winn, Joshua N. [Department of Physics, and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Ryu, Tsuguru; Onitsuka, Masahiro [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Kudo, Tomoyuki [Subaru Telescope, 650 North A’ohoku Place, Hilo, HI 96720 (United States); Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel [Institut d’Astrophysique et de Géophysique, Université de Liège, Allée du 6 Août 17, Bat. B5C, B-4000 Liège (Belgium); McCormac, James [Department of Physics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL (United Kingdom); Holman, Matthew [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Izumiura, Hideyuki, E-mail: norio.narita@nao.ac.jp [SOKENDAI (The Graduate University for Advanced Studies), 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan)

    2015-12-10

    K2-19 (EPIC201505350) is an interesting planetary system in which two transiting planets with radii ∼7 R{sub ⊕} (inner planet b) and ∼4 R{sub ⊕} (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2 m telescope. We find that the host star is a relatively old (≥8 Gyr) late G-type star (T{sub eff} ∼ 5350 K, M{sub s} ∼ 0.9 M{sub ⊙}, and R{sub s} ∼ 0.9 R{sub ⊙}). We do not find any contaminating faint objects near the host star that could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2 m telescope, TRAPPISTCAM on the TRAPPIST 0.6 m telescope, and MuSCAT on the OAO 1.88 m telescope. We confirm the presence of transit timing variations (TTVs), as previously reported by Armstrong and coworkers. We model the observed TTVs of the inner planet using the synodic chopping formulae given by Deck and Agol. We find two statistically indistinguishable solutions for which the period ratios (P{sub c}/P{sub b}) are located slightly above and below the exact 3:2 commensurability. Despite the degeneracy, we derive the orbital period of the inner planet P{sub b} ∼ 7.921 days and the mass of the outer planet M{sub c} ∼ 20 M{sub ⊕}. Additional transit photometry (especially for the outer planet) as well as precise radial-velocity measurements would be helpful to break the degeneracy and to determine the mass of the inner planet.

  20. Subarachnoid Transplant of the Human Neuronal hNT2.19 Serotonergic Cell Line Attenuates Behavioral Hypersensitivity without Affecting Motor Dysfunction after Severe Contusive Spinal Cord Injury

    Directory of Open Access Journals (Sweden)

    Mary J. Eaton

    2011-01-01

    Full Text Available Transplant of cells which make biologic agents that can modulate the sensory and motor responses after spinal cord injury (SCI would be useful to treat pain and paralysis. To address this need for clinically useful human cells, a unique neuronal cell line that synthesizes and secretes/releases the neurotransmitter serotonin (5HT was isolated. Hind paw tactile allodynia and thermal hyperalgesia induced by severe contusive SCI were potently reversed after lumbar subarachnoid transplant of differentiated cells, but had no effect on open field motor scores, stride length, foot rotation, base of support, or gridwalk footfall errors associated with the SCI. The sensory effects appeared 1 week after transplant and did not diminish during the 8-week course of the experiment when grafts were placed 2 weeks after SCI. Many grafted cells were still present and synthesizing 5HT at the end of the study. These data suggest that the human neuronal serotonergic hNT2.19 cells can be used as a biologic minipump for receiving SCI-related neuropathic pain, but likely requires intraspinal grafts for motor recovery.

  1. Clinical Management and Follow-up of Hypercholesterolemia Among Perinatally HIV-Infected Children Enrolled in the PACTG 219C Study

    Science.gov (United States)

    Jacobson, Denise L.; Williams, Paige; Tassiopoulos, Katherine; Melvin, Ann; Hazra, Rohan; Farley, John

    2011-01-01

    Background Hypercholesterolemia is common in perinatally HIV-infected (HIV+) children, but little is known about the clinical course and management in this population. Methods We studied HIV+ children in a multisite prospective cohort study (PACTG 219C) and considered follow-up for two years after development of hypercholesterolemia. We estimated the time to and factors associated with resolution of hypercholesterolemia and described changes in ARV regimen and use of lipid-lowering medications. We defined incident hypercholesterolemia as entry total cholesterol (cholesterol) hypercholesterolemia as two consecutive cholesterol hypercholesterolemia. Results Among 240 incident hypercholesterolemia cases, 81 (34%) had resolution to normal cholesterol within two years of follow-up (median follow-up = 1.9 years). The median age of cases was 10.3 years with 54% Non-Hispanic black and 53% male. Resolution to normal cholesterol was more likely in children who changed ARV regimen (adjusted Hazard Ratio (aHR) = 2.37, 95%CI 1.45, 3.88) and who were ≥ 13 years old (aHR=2.39, 95%CI 1.33, 4.27). Types of regimen changes varied greatly and 15 children began statins. Conclusions The majority of children who develop hypercholesterolemia maintain elevated levels over time, potentially placing them at risk for premature cardiovascular morbidity. PMID:21602698

  2. In-Source Laser Spectroscopy with the Laser Ion Source and Trap: First Direct Study of the Ground-State Properties of ^{217,219}Po

    Directory of Open Access Journals (Sweden)

    D. A. Fink

    2015-02-01

    Full Text Available A Laser Ion Source and Trap (LIST for a thick-target, isotope-separation on-line facility has been implemented at CERN ISOLDE for the production of pure, laser-ionized, radioactive ion beams. It offers two modes of operation, either as an ion guide, which performs similarly to the standard ISOLDE resonance ionization laser ion source (RILIS, or as a more selective ion source, where surface-ionized ions from the hot ion-source cavity are repelled by an electrode, while laser ionization is done within a radio-frequency quadrupole ion guide. The first physics application of the LIST enables the suppression of francium contamination in ion beams of neutron-rich polonium isotopes at ISOLDE by more than 1000 with a reduction in laser-ionization efficiency of only 20. Resonance ionization spectroscopy is performed directly inside the LIST device, allowing the study of the hyperfine structure and isotope shift of ^{217}Po for the first time. Nuclear decay spectroscopy of ^{219}Po is performed for the first time, revealing its half-life, α-to-β-decay branching ratio, and α-particle energy. This experiment demonstrates the applicability of the LIST at radioactive ion-beam facilities for the production and study of pure beams of exotic isotopes.

  3. Transient climate simulations of the deglaciation 21-9 thousand years before present (version 1) - PMIP4 Core experiment design and boundary conditions

    Science.gov (United States)

    Ivanovic, Ruza F.; Gregoire, Lauren J.; Kageyama, Masa; Roche, Didier M.; Valdes, Paul J.; Burke, Andrea; Drummond, Rosemarie; Peltier, W. Richard; Tarasov, Lev

    2016-07-01

    The last deglaciation, which marked the transition between the last glacial and present interglacial periods, was punctuated by a series of rapid (centennial and decadal) climate changes. Numerical climate models are useful for investigating mechanisms that underpin the climate change events, especially now that some of the complex models can be run for multiple millennia. We have set up a Paleoclimate Modelling Intercomparison Project (PMIP) working group to coordinate efforts to run transient simulations of the last deglaciation, and to facilitate the dissemination of expertise between modellers and those engaged with reconstructing the climate of the last 21 000 years. Here, we present the design of a coordinated Core experiment over the period 21-9 thousand years before present (ka) with time-varying orbital forcing, greenhouse gases, ice sheets and other geographical changes. A choice of two ice sheet reconstructions is given, and we make recommendations for prescribing ice meltwater (or not) in the Core experiment. Additional focussed simulations will also be coordinated on an ad hoc basis by the working group, for example to investigate more thoroughly the effect of ice meltwater on climate system evolution, and to examine the uncertainty in other forcings. Some of these focussed simulations will target shorter durations around specific events in order to understand them in more detail and allow for the more computationally expensive models to take part.

  4. 乙醇、微小RNA-219-5p对肝癌细胞中聚糖蛋白3表达的影响%Effects of alcohol and microRNA-219-5p on proteoglycan 3 in hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    李辉; 曹会存; 刘诗义; 刘健; 曹广劭; 赵晓阳

    2015-01-01

    Objective To observe the effects of alcohol and microRNA (miRNA)-219-5p on proteoglycan 3 (GPC3) in hepatocullular carcinoma (HCC).Methods Immunohistochemical staining method was used to detect the expression of 30 cases of normal liver tissues,120 cases of HCC tissues and corresponding para-concerous liver tissues.The relationship between GPC3 and clinical data of Han patients with HCC,and the inner link between GPC3 with alcohol and miRNA-219-5p were analyzed.Results The GPC3 positive expression was 75% in HCC tissues and 30% in para-cancerous tissues (x2 =74.348,P <0.01).No GPC3 expression was detected in normal liver tissues.The GPC3 expression was not related to age,positive hepatitis B surface antigen (HBsAg),history of chronic liver disease and tumor size [x2(HCC tissues) =1.800,0.533,1.140,0.568,P > 0.05;x2(para-cancerous tissues) =0.179,0,0,0.714,P > 0.05).The GPC3 positive expression rate was 100% in patients with heavy drinking,and that was 70% in non-heavy drinking patients.(x2 =8.000,P < 0.01),suggesting drinking behavior had a significant relevance with the GPC3 expression.Conclusion The occurrence of HCC is correlated with the low expression of miRAN-219 and high expression of GPC3 protein.At the same time,heavy drinking behavior can enlarge this effect.%目的 观察乙醇、微小RNA(miRNA)-219-5p对肝细胞肝癌(HCC)中聚糖蛋白3(GPC3)表达的影响.方法 采用免疫组织化学检测30例正常肝脏组织、120例HCC患者肝癌组织及相应癌旁组织标本中GPC3蛋白的表达水平,分析GPC3与HCC汉族临床资料之间的关系,探讨其与饮酒、miRNA-219-5p相关性.结果 GPC3在HCC组织中的阳性表达率为75%,在癌旁组织中其阳性表达率为30%,正常肝组织中未发现其阳性表达,3组比较差异有统计学意义(x2=74.348,P<0.01).在年龄、乙型肝炎表面抗原(HBsAg)阳性、慢性肝病病史以及肿瘤大小方面,GPC3表达均未受到影响[x2(肝癌组织)=1.800、0

  5. The addition of submergence-tolerant Sub1 gene into high yielding MR219 rice variety and analysis of its BC2F3 population in terms of yield and yield contributing characters to select advance lines as a variety

    Directory of Open Access Journals (Sweden)

    Fahim Ahmed

    2016-09-01

    Full Text Available A cross was made between MR219 (high yielding but submergence intolerant and Swarna-Sub1 (submergence tolerant to produce submergence-tolerant rice variety using the marker-assisted backcrossing (MABC method to protect the farmers of low-lying land from flash floods during rain. Knowledge of yield and yield contributing factors plays a vital role in the selection process of a variety. This experim ent was designed to determine the genetic diversity among recently produced different lines of BC2F3 population and also to compare all the lines with MR219 to find the best one. Agronomical, yield and yield contributing data were taken, while genotypic and phenotypic coefficients, variance components and heritability were estimated. Introgression of the target gene, Sub1, was done using tightly linked marker, and also background recovery was measured using simple sequence repeat (SSR markers in different generations. The observed recurrent parent genome (RPG recovery of BC2F2 generation was 95.37%, which indicates high-level similarity between the recurrent parent (MR219 and the resulting lines. Thirty newly developed lines of BC2F3 population, resulting backcross of MR219 and Swarna-Sub1, were planted with four replications following randomised complete block design (RCBD. Newly developed lines were grouped into four clusters based on traits with UPGMA dendrogram and cluster analysis to select the 10 best plants. This study will help the future researchers to select the best plants of a breeding programme after introgression of a gene considering phenotype performances to develop new varieties.

  6. ø219.1/168.3 mm 气举反循环双壁钻具及其在大直径工程井中的应用%ø219.1/168.3 mm Air-lift RC Dual Wall Drilling Tools and Their Use in Large Diameter Drilling

    Institute of Scientific and Technical Information of China (English)

    熊亮; 袁志坚; 白领国; 彭桂湘; 耿建国

    2013-01-01

    Considering the shortcomings such as low efficiency, long construction period, high risk etc.of the commonly used large diameter drilling process which consists of direct circulation drilling and stepped reaming, a219.1/168.3 mm dual-wall, and168.3 mm internal flush drill pipes have been developed with the complete accessories, and successfully used to drilling a 1200 mm diameter , 651.2 m deep gas drainage well.The drilling tool is large in size, has high strength, and is connected with special threads.Field use indicates that the drilling tool has high tensile and torsional strength with good sealing.Compared with conventional drilling processes, the air-lift reverse circulation technique provides good cutting-carrying capacity, and increases the rate of penetrate by 74.3% with the quality borehole.In addition, drilling risk is greatly reduced owing to cleanliness of the borehole.%针对当前国内普遍采用“正循环回转钻进+分级扩孔”方法施工大直径工程井效率低、周期长、工程风险大等不足,研制了饱219.1/168.3 mm气举反循环双壁钻具和饱168.3 mm内平单壁钻具及配套附属器具,并成功应用于某直径1200 mm、深651.2 m的大口径瓦斯抽排井。该套钻具尺寸大,强度高,采用特殊螺纹连接。现场应用表明,钻具抗拉、抗扭强度高,密封性能好,应用气举反循环施工较传统工艺携岩效果好,机械钻速提高74.3%,井身质量优。此外,由于井内干净,钻井风险也得以大幅降低。

  7. Evaluation of Adenosine Triphosphate-Binding Cassette Transporter A1 (ABCA1) R219K and C-Reactive Protein Gene (CRP) +1059G/C Gene Polymorphisms in Susceptibility to Coronary Heart Disease.

    Science.gov (United States)

    Li, Jing-Fang; Peng, Dian-Ying; Ling, Mei; Yin, Yong

    2016-08-25

    BACKGROUND This meta-analysis investigated the correlation of ABCA1 R219K and C-Reactive Protein Gene (CRP) +1059G/C gene polymorphisms with susceptibility to coronary heart disease (CHD). MATERIAL AND METHODS We searched PubMed, Springer link, Wiley, EBSCO, Ovid, Wanfang database, VIP database, and China National Knowledge Infrastructure (CNKI) databases to retrieve published studies by keyword. Searches were filtered using our stringent inclusion and exclusion criteria. Resultant high-quality data collected from the final selected studies were analyzed using Comprehensive Meta-analysis 2.0 software. Eleven case-control studies involving 3053 CHD patients and 3403 healthy controls met our inclusion criteria. Seven studies were conducted in Asian populations, 3 studies were done in Caucasian populations, and 1 was in an African population. RESULTS Our major finding was that ABCA1 R219K polymorphism increased susceptibility to CHD in allele model (OR=0.729, 95% CI=0.559~0.949, P=0.019) and dominant model (OR=0.698, 95% CI=0.507~0.961, P=0.027). By contrast, we were unable to find any significant association between the CRP +1059G/C polymorphism and susceptibility to CHD (allele model: OR=1.170, 95% CI=0.782~1.751, P=0.444; dominant model: OR=1.175, 95% CI=0.768~1.797, P=0.457). CONCLUSIONS This meta-analysis provides convincing evidence that polymorphism of ABCA1 R219K is associated with susceptibility to CHD while the CRP +1059G/C polymorphism appears to have no correlation with susceptibility to CHD.

  8. Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

    Directory of Open Access Journals (Sweden)

    Mary J. Eaton

    2012-01-01

    Full Text Available Effective treatment of sensory neuropathies in peripheral neuropathies and spinal cord injury (SCI is one of the most difficult problems in modern clinical practice. Cell therapy to release antinociceptive agents near the injured spinal cord is a logical next step in the development of treatment modalities. But few clinical trials, especially for chronic pain, have tested the potential of transplant of cells to treat chronic pain. Cell lines derived from the human neuronal NT2 cell line parentage, the hNT2.17 and hNT2.19 lines, which synthesize and release the neurotransmitters gamma-aminobutyric acid (GABA and serotonin (5HT, respectively, have been used to evaluate the potential of cell-based release of antinociceptive agents near the lumbar dorsal (horn spinal sensory cell centers to relieve neuropathic pain after PNS (partial nerve and diabetes-related injury and CNS (spinal cord injury damage in rat models. Both cell lines transplants potently and permanently reverse behavioral hypersensitivity without inducing tumors or other complications after grafting. Functioning as cellular minipumps for antinociception, human neuronal precursors, like these NT2-derived cell lines, would likely provide a useful adjuvant or replacement for current pharmacological treatments for neuropathic pain.

  9. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228

    Energy Technology Data Exchange (ETDEWEB)

    Aleissa, Khalid A.; Almasoud, Fahad I.; Islam, Mohammed S. [Atomic Energy Research Institute, King Abdul Aziz City for Science and Technology, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); L' Annunziata, Michael F. [IAEA Expert, Montague Group, P.O. Box 5033, Oceanside, CA 92052-5033 (United States)], E-mail: mlannunziata@cox.net

    2008-12-15

    The activities of {sup 228}Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide {sup 228}Ac. The radium was pre-concentrated on MnO{sub 2} and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter {sup 228}Ra({sup 228}Ac), the daughter nuclide {sup 228}Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by {sup 228}Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9{+-}0.1% was measured for {sup 228}Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317{+-}0.013 cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1 g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of {sup 228}Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for {sup 228}Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure {sup 228}Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  10. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228.

    Science.gov (United States)

    Aleissa, Khalid A; Almasoud, Fahad I; Islam, Mohammed S; L'Annunziata, Michael F

    2008-12-01

    The activities of (228)Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide (228)Ac. The radium was pre-concentrated on MnO(2) and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter (228)Ra((228)Ac), the daughter nuclide (228)Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by (228)Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9+/-0.1% was measured for (228)Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317+/-0.013cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of (228)Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for (228)Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure (228)Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  11. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    Energy Technology Data Exchange (ETDEWEB)

    Rakhimov, A.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz); Warot, G. [CEA-CNRS, Modane (France). Laboratoire Souterrain de Modane (LSM); Karaivanov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Institute for Nuclear Research and Nuclear Energy (INRNE), Sofia (Bulgaria); Kochetov, O.I.; Lebedev, N.A.; Filosofov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Mukhamedshina, N.M.; Sadikov, I.I. [Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz)

    2013-07-01

    A technique of selenium purification from {sup 232}Th, {sup 238}U, {sup 226,228}Ra, {sup 227}Ac and {sup 40}K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  12. The release of dissolved actinium to the ocean: A global comparison of different end-members

    Science.gov (United States)

    Geibert, W.; Charette, M.; Kim, G.; Moore, W.S.; Street, J.; Young, M.; Paytan, A.

    2008-01-01

    The measurement of short-lived 223Ra often involves a second measurement for supported activities, which represents 227Ac in the sample. Here we exploit this fact, presenting a set of 284 values on the oceanic distribution of 227Ac, which was collected when analyzing water samples for short-lived radium isotopes by the radium delayed coincidence counting system. The present work compiles 227Ac data from coastal regions all over the northern hemisphere, including values from ground water, from estuaries and lagoons, and from marine end-members. Deep-sea samples from a continental slope off Puerto Rico and from an active vent site near Hawaii complete the overview of 227Ac near its potential sources. The average 227Ac activities of nearshore marine end-members range from 0.4??dpm m- 3 at the Gulf of Mexico to 3.0??dpm m- 3 in the coastal waters of the Korean Strait. In analogy to 228Ra, we find the extension of adjacent shelf regions to play a substantial role for 227Ac activities, although less pronounced than for radium, due to its weaker shelf source. Based on previously published values, we calculate an open ocean 227Ac inventory of 1.35 * 1018??dpm 227Acex in the ocean, which corresponds to 37??moles, or 8.4??kg. This implies a flux of 127??dpm m-2 y- 1 from the deep-sea floor. For the shelf regions, we obtain a global inventory of 227Ac of 4.5 * 1015??dpm, which cannot be converted directly into a flux value, as the regional loss term of 227Ac to the open ocean would have to be included. Ac has so far been considered to behave similarly to Ra in the marine environment, with the exception of a strong Ac source in the deep-sea due to 231Paex. Here, we present evidence of geochemical differences between Ac, which is retained in a warm vent system, and Ra, which is readily released [Moore, W.S., Ussler, W. and Paull, C.K., 2008-this issue. Short-lived radium isotopes in the Hawaiian margin: Evidence for large fluid fluxes through the Puna Ridge. Marine Chemistry]. Another potential mechanism of producing deviations in 227Ac/228Ra and daughter isotope ratios from the expected production value of lithogenic material is observed at reducing environments, where enrichment in uranium may occur. The presented data here may serve as a reference for including 227Ac in circulation models, and the overview provides values for some end-members that contribute to the global Ac distribution. ?? 2007 Elsevier B.V. All rights reserved.

  13. Potential population-level nutritional impact of replacing whole and reduced-fat milk with low-fat and skim milk among US children aged 2-19 years.

    Science.gov (United States)

    Rehm, Colin D; Drewnowski, Adam; Monsivais, Pablo

    2015-01-01

    Dietary guidance emphasizes plain low-fat and skim milk over whole, reduced-fat, and flavored milk (milk eligible for replacement [MER]). The objective of this study was to evaluate the population-level impact of such a change on energy, macronutrient and nutrient intakes, and diet cost. Cross-sectional modeling study. Data from the 2001-2002 and 2003-2004 National Health and Nutrition Examination Survey. A total of 8,112 children aged 2-19 years. Energy, macronutrient, and micronutrient intake before and after replacement of MER with low-fat or skim milk. Survey-weighted linear regression models. Milk eligible for replacement accounted for 46% of dairy servings. Among MER consumers, replacement with skim or low-fat milk would lead to a projected reduction in energy of 113 (95% confidence interval [CI], 107-119) and 77 (95% CI, 73-82) kcal/d and percent energy from saturated fat by an absolute value of 2.5% of total energy (95% CI, 2.4-2.6) and 1.4% (95% CI, 1.3-1.5), respectively. Replacement of MER does not change diet costs or calcium and potassium intake. Substitution of MER has the potential to reduce energy and total and saturated fat intake with no impact on diet costs or micronutrient density. The feasibility of such replacement has not been examined and there may be negative consequences if replacement is done with non-nutrient-rich beverages. Copyright © 2015. Published by Elsevier Inc.

  14. 6 CFR 21.9 - Compliance information.

    Science.gov (United States)

    2010-01-01

    ... its obligations under this part. In general, recipients should have available for the Secretary racial and ethnic data showing the extent to which members of minority groups are beneficiaries of programs... necessary to apprise such persons of the protections against discrimination assured them by the Act and...

  15. 32 CFR 219.102 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... physical or psychological examinations or tests. (j) Certification means the official notification by the... agency solely as part of the department's or agency's broader responsibility to regulate certain types of...

  16. 36 CFR 219.2 - Principles.

    Science.gov (United States)

    2010-07-01

    ... interdependence of national forests and grasslands with economies and communities. (2) Planning fosters strategies... by the knowledge and values of the American people. (1) Planning encourages extensive collaborative...

  17. 36 CFR 219.20 - Ecological sustainability.

    Science.gov (United States)

    2010-07-01

    ... diversity and species diversity are components of ecological sustainability. The planning process must..., abundance, and distribution of aquatic and riparian systems including streams, stream banks, coastal waters, estuaries, groundwater, lakes, wetlands, shorelines, riparian areas, and floodplains; stream channel...

  18. 49 CFR 219.5 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... Board (49 CFR part 1201; General Instructions 1-1). Controlled substance has the meaning assigned by 21...; (2) Impact of rail equipment with obstructions such as fallen trees, rock or snow slides, livestock... authorized to practice by the state. NTSB means the National Transportation Safety Board. Passenger...

  19. Reference: 219 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available on. Phosphatidylinositol (PtdIns)(4,5)P(2) is one of the best characterized PIs; studies... homologs are found in nonplant genomes. High-performance liquid chromatography studies show that unstressed

  20. 22 CFR 219.103 - Definitions.

    Science.gov (United States)

    2010-04-01

    ...” includes, but is not limited to, such diseases and conditions as orthopedic, visual, speech, and hearing impairments, cerebral palsy, epilepsy, muscular dystrophy, multiple sclerosis, cancer, heart disease, diabetes...

  1. 12 CFR 219.3 - Cost reimbursement.

    Science.gov (United States)

    2010-01-01

    ... that the financial institution use programming or other higher level technical services of a computer... of extracting electronically stored records, based on computer time and necessary supplies; however, personnel time for computer searches may be paid for at the rates set for computer support...

  2. 49 CFR 372.219 - Washington, DC

    Science.gov (United States)

    2010-10-01

    ... and is comprised of all points as follows: (a) The municipality of Washington, D.C., itself; (b) All... Manassas, VA, and the City of Manassas Park, VA. (d) All of any municipality any part of which is within... municipality wholly surrounded, or so surrounded except for a water boundary, by the municipality of...

  3. 12 CFR 219.2 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... Credit Protection Act (15 U.S.C. 1602(n)), industrial loan company, trust company, savings association... finance institution, located in any State or territory of the United States, the District of Columbia...

  4. 36 CFR 219.36 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... species diversity or their high social, cultural or economic value. Disturbance regime: Actions, functions... plant species that are characteristic of the macroclimate and geology of the region or sub-region... economic sustainability: Meeting the economic, social, aesthetic, and cultural needs and desires of current...

  5. 46 CFR 10.219 - Fees.

    Science.gov (United States)

    2010-10-01

    ... rating 50 45 45 STCW certification: Original No fee No fee No fee Renewal No fee No fee No fee Reissue... address for sending payment by mail can be found at http://www.uscg.mil/stcw/ldcr-userfees.htm. (4) Checks... regarding current forms of electronic payment, go to http://www.uscg.mil/stcw/ldcr-userfees.htm. (e)...

  6. Association between ε2/3/4, Promoter Polymorphism (−491A/T, −427T/C, and −219T/G at the Apolipoprotein E Gene, and Mental Retardation in Children from an Iodine Deficiency Area, China

    Directory of Open Access Journals (Sweden)

    Jun Li

    2014-01-01

    Full Text Available Background. Several common single-nucleotide polymorphisms (SNPs at apolipoprotein E (ApoE have been linked with late onset sporadic Alzheimer’s disease and declining normative cognitive ability in elder people, but we are unclear about their relationship with cognition in children. Results. We studied -491A/T, -427T/C, and -219G/T promoter polymorphisms and ε2/ε3/ε4 at ApoE among children with mental retardation (MR, n=130, borderline MR (n=124, and controls (n=334 from an iodine deficiency area in China. The allelic and genotypic distribution of individual locus did not significantly differ among three groups with Mantel-Haenszel χ2 test (P>0.05. However, frequencies of haplotype of -491A/-427T/-219T/ε4 were distributed as MR > borderline MR > controls (P uncorrected = 0.004, indicating that the presence of this haplotype may increase the risk of disease. Conclusions. In this large population-based study in children, we did not find any significant association between single locus of the four common ApoE polymorphisms (-491A/T, -427T/C, -219T/G, and ε2/3/4 and MR or borderline MR. However, we found that the presence of ATTε4 haplotype was associated with an increased risk of MR and borderline MR. Our present work may help enlarge our knowledge of the cognitive role of ApoE across the lifespan and the mechanisms of human cognition.

  7. Polymorphisms in miR-135a-2, miR-219-2 and miR-211 as well as their interaction with cooking oil fume exposure on the risk of lung cancer in Chinese nonsmoking females: a case-control study.

    Science.gov (United States)

    Yin, Zhihua; Cui, Zhigang; Li, Hang; Ren, Yangwu; Qian, Biyun; Rothman, Nathaniel; Lan, Qing; Zhou, Baosen

    2016-09-23

    The associations between microRNAs and lung cancer have received increasing attention. This study assess the association between polymorphisms in miR-135a-2, miR-219-2 and miR-211 genes and the risk of lung cancer, as well as the gene-environment interaction between these polymorphisms and cooking oil fume exposure. A case-control study featuring 268 cases and 266 controls was conducted. The associations of miR-135a-2 rs10459194, miR-219-2 rs10988341 and miR-211 rs1514035 polymorphisms with the risk of lung cancer were analyzed. The gene-environment interactions were also reported on both additive and multiplicative scales. There were no statistically significant associations between the single-nucleotide polymorphisms (SNPs) and lung cancer or lung adenocarcinoma. The individuals with both a risk genotype of miRNA SNPs and exposure to a risk factor (cooking oil fumes) were at higher risk of lung cancer than those with only one of these two risk factors (odd ratios of 2.208, 1.285 and 1.813 for miR-135a-2 rs10459194; 2.164, 1.209 and 1.806 for miR-219-2 rs10988341; and 2.122, 1.146 and 1.725 for miR-211 rs1514035, respectively). However, the measures of biological interaction indicate that there was no such interaction between the three SNPs and exposure to cooking oil fumes on an additive scale. Logistic regression models also suggested that the gene-environment interactions were not statistically significant on a multiplicative scale. There were no significant associations between the polymorphisms in miRNAs (miR-26a-1 rs7372209, miR-605 rs2043556 and miR-16-1 rs1022960) and the risk of lung cancer in the Chinese nonsmoking female population. The interactions between these polymorphisms in miRNAs and cooking oil fume exposure were also not statistically significant.

  8. Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy; Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie

    Energy Technology Data Exchange (ETDEWEB)

    Marx, Sebastian Markus

    2014-09-23

    The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.

  9. ATP结合盒转运子1R219K基因多态性与阿尔茨海默病相关性研究%Research on association between polymorphism of ATP-binding cassette transporter A1 and Alzheimer's disease

    Institute of Scientific and Technical Information of China (English)

    王娟; 陈卫蓉; 肖志杰

    2013-01-01

    Objective To assess the effect of single-nucleotide polymorphisms (SNPs) in the cholesterol-related genes ABCA1 exon R219K variation on the risk of AD and cognitive function.Methods Using case-control study,a total of sporadic 104 AD patients and 104 individuals above 60 years without cognitive impairment from a population of Chinese Han nationality in Changsha area were studied to determine the polymorphisms of ABCA1 R219K.Adopt SPSS 13.0 for statistical analysis.Results There were significant differences in the frequencies of three genotypes (RR、RK and KK) between the AD patients and controls (x2 =8.777,P =0.012).The frequency of KK genotype in AD group is obviously lower than that of controls (x2 =5.261,P =0.022).The frequency of KK+RK genotype in AD patients was 54.8%,was significantly lower than that of controls (70.2%,P =0.022).There was significantly higher levels of HDL-C,apoA-I and cognitive scores in the carriers of KK genotype and K allele (P < 0.05).There was significantly higher levels of MMSE and WMS scores in the carriers of K K genotype and K allele (P < 0.05).Further in accordance with memory types including long-term memory,short-term memory,transient memory,compared with RR genotype,the scores of short-term memory,transient memory of RK,KK and RK + KK genotypes were higher (P < 0.05),but there was no significant difference in the score of long-term memory (P > 0.05).Multifactor logistic regression analysis showed that carrying K allele was a single protective factor for AD.Conclusions The polymorphism of ABCA1R219K is associated with AD.Carrying K allele may play a positive role in serum lipids and cognition,and produce a protective effect on risk of AD.%目的 探讨胆固醇相关基因ABCA1外显子R219K遗传变异对阿尔茨海默病(AD)发病风险及认知功能的影响.方法 采用病例对照研究方法测定湖南长沙地区汉族人群104例散发性AD患者以及104名60岁以上认知功能正常者的ABCA1R219K

  10. Production of actinium, thorium and radium isotopes from natural thorium irradiated with protons up to 141 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Ermolaev, S.V.; Zhuikov, B.L.; Kokhanyuk, V.M.; Matushko, V.L. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Research; Kalmykov, S.N. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Chemistry Dept.; Aliev, R.A. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Skobeltsyn Inst. of Nuclear Physics; Tananaev, I.G.; Myasoedov, B.F. [Russian Academy of Sciences, Moscow (Russian Federation). A.N. Frumkin Inst. of Physical Chemistry and Electrochemistry

    2012-07-01

    Cross sections of {sup 225}Ac, {sup 227}Ac, {sup 227}Th and {sup 228}Th in thorium-232 targets irradiated with protons in the energy range 21-141 MeV have been measured. Based on these data, production yields of {sup 225}Ac and {sup 223}Ra in thick thorium targets have been calculated. It is possible to produce in proton energy range 60-140 MeV about 96 GBq (2.6 Ci) {sup 225}Ac per 10-d irradiation with 100 {mu}A proton beam current and 10-d decay, and much higher amount of {sup 223}Ra. The impurities of {sup 227}Ac and {sup 224}Ra are important and need to be assessed for further medical applications. (orig.)

  11. Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J; O' Donoghue, J A; Humm, J L [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); Jaggi, J S [Bristol-Myers Squibb, Plainsboro, NJ (United States); Ruan, S; Larson, S M [Nuclear Medicine Service Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); McDevitt, M; Scheinberg, D A, E-mail: schwarj1@mskcc.org [Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065 (United States)

    2011-02-07

    Clinical therapeutic studies using {sup 225}Ac-labeled antibodies have begun. Of major concern is renal toxicity that may result from the three alpha-emitting progeny generated following the decay of {sup 225}Ac. The purpose of this study was to determine the amount of {sup 225}Ac and non-equilibrium progeny in the mouse kidney after the injection of {sup 225}Ac-huM195 antibody and examine the dosimetric consequences. Groups of mice were sacrificed at 24, 96 and 144 h after injection with {sup 225}Ac-huM195 antibody and kidneys excised. One kidney was used for gamma ray spectroscopic measurements by a high-purity germanium (HPGe) detector. The second kidney was used to generate frozen tissue sections which were examined by digital autoradiography (DAR). Two measurements were performed on each kidney specimen: (1) immediately post-resection and (2) after sufficient time for any non-equilibrium excess {sup 213}Bi to decay completely. Comparison of these measurements enabled estimation of the amount of excess {sup 213}Bi reaching the kidney ({gamma}-ray spectroscopy) and its sub-regional distribution (DAR). The average absorbed dose to whole kidney, determined by spectroscopy, was 0.77 (SD 0.21) Gy kBq{sup -1}, of which 0.46 (SD 0.16) Gy kBq{sup -1} (i.e. 60%) was due to non-equilibrium excess {sup 213}Bi. The relative contributions to renal cortex and medulla were determined by DAR. The estimated dose to the cortex from non-equilibrium excess {sup 213}Bi (0.31 (SD 0.11) Gy kBq{sup -1}) represented {approx}46% of the total. For the medulla the dose contribution from excess {sup 213}Bi (0.81 (SD 0.28) Gy kBq{sup -1}) was {approx}80% of the total. Based on these estimates, for human patients we project a kidney-absorbed dose of 0.28 Gy MBq{sup -1} following administration of {sup 225}Ac-huM195 with non-equilibrium excess {sup 213}Bi responsible for approximately 60% of the total. Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of {sup 225}Ac radioimmunotherapy.

  12. 49 CFR 219.903 - Retention of drug testing records.

    Science.gov (United States)

    2010-10-01

    .... (4) Records related to employee training: (i) Materials on drug abuse awareness, including a copy of... the following records for a minimum of five years: (i) A summary record of each covered employee's... verifying the existence of a medical explanation of the inability of a covered employee to provide...

  13. Dicty_cDB: VFB219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ( AY785660 |pid:none) Trypanosoma cruzi strain Dm 28 c c... 405 e-111 AY785657_1( AY785657 |pid:none) Trypanosoma cruzi strain Colomb...ian... 405 e-111 protein update 2009. 6.17 PSORT psg: 0.

  14. 49 CFR 219.203 - Responsibilities of railroads and employees.

    Science.gov (United States)

    2010-10-01

    ... involved in the accident or incident. In any case where an operator, dispatcher, signal maintainer or other... duty tour. An employee who has been transported to receive medical care is not released from duty...

  15. 48 CFR 52.219-2 - Equal Low Bids.

    Science.gov (United States)

    2010-10-01

    ...) This provision applies to small business concerns only. (b) The bidder's status as a labor surplus area...) amount to more than 50 percent of the contract price. (c) Failure to identify the labor surplus areas...

  16. 48 CFR 219.806 - Pricing the 8(a) contract.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... officer shall notify the SBA prior to withdrawing a requirement from the 8(a) Program due to failure...

  17. 36 CFR 219.18 - Role of advisory committees.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... variety of public purposes, particularly those groups organized to develop landscape goals (§...

  18. Dicty_cDB: VSF219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available lated Amino Acid sequence (All Frames) Frame A: qchhlkpspentpsistrdstelpsriepqkls... pryqerstqspchplkkekrr*krn*kiihccfishrqelqrspnqksc*QLNGLIKINF LIYFKKK--- ---sqchhlkpspentpsistrdstelpsriepqk

  19. Dicty_cDB: SLF219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ne pCCA5. 385 e-122 3 K03070 |K03070.1 Slime mold (D.discoideum) DIRS-1 right inverted terminal repeat, clon...e CP19-1. 226 e-119 4 K03072 |K03072.1 Slime mold (D.discoideum) DIRS-1 right inverted... terminal repeat, clone SB63. 238 e-114 3 K03068 |K03068.1 Slime mold (D.discoideum) DIRS-1 right inverted... terminal repeat, clone GM45. 167 e-110 5 K03069 |K03069.1 Slime mold (D.discoideum) DIRS-1 left inverted

  20. 49 CFR 219.405 - Co-worker report policy.

    Science.gov (United States)

    2010-10-01

    ... dependence on alcohol or a drug or by another identifiable and treatable mental or physical disorder involving the abuse of alcohol or drugs as a primary manifestation, the following conditions and procedures... that affords more favorable conditions to employees troubled by alcohol or drug abuse...

  1. 219 original article seroprevalence of hepatitis c virus (hcv)

    African Journals Online (AJOL)

    boaz

    enlightenment of this problem. All pregnant women should be ... problems, including hepatocellular carcinoma (HCC). (5). ... instructions. ELISA method: Enzyme-linked immunosorbent assay ... Substrate solution (100 l) was pippeted to each well and was .... benefit from modern therapy with interferon and ribavirin which ...

  2. Dicty_cDB: SSC219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available gy vs DNA Score E Sequences producing significant alignments: (bits) Value N AC116984 |AC116984.2 Dictyostelium discoideum chromo....2 Dictyostelium discoideum chromosome 2 map 1004546-1005075 strain AX4, complete... sequence. 42 0.051 2 AC116955 |AC116955.2 Dictyostelium discoideum chromosome 2 map 5455881-5481449 strain ...AX4, complete sequence. 46 0.054 3 AC114261 |AC114261.2 Dictyostelium discoideum chromosome 2 map 126059-159...710 strain AX4, complete sequence. 46 0.37 1 AC006278 |AC006278.8 Plasmodium falciparum chromosome 12 clone

  3. 36 CFR 219.17 - Interaction with private landowners.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... activities; (c) Potential conditions and activities on the adjacent lands that may affect management...

  4. 36 CFR 219.13 - Coordination among Federal agencies.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... proposed actions; (b) For the streamlined coordination of Federal agency policies, resource management... management plans....

  5. 36 CFR 219.24 - Science consistency evaluations.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Contribution of Science... available science. (b) The science advisory board is responsible for organizing and conducting a...

  6. Dicty_cDB: SSD219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LYLYYT SGEKKDIPFVPKFAPAFNPKTAGSHSGTKGAKGVVKSKHG*ik*******ii*yits*st fqsysnsthyhyhhiqnlkpkkkkkkkkkkklynnc--- ...YLYYT SGEKKDIPFVPKFAPAFNPKTAGSHSGTKGAKGVVKSKHG*ik*******ii*yits*st fqsysnsthyhyhhiqnlkpkkkkkkkkkkklynn

  7. 1935 15' Quad #219 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  8. 48 CFR 1052.219-71 - Subcontracting Plan.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Subcontracting Plan. 1052... Subcontracting Plan. As prescribed in DTAR 1019.708-70(b), insert the following provision: Subcontracting Plan (MAR 2002) As part of its initial proposal, each large business offeror must submit a contracting...

  9. 12 CFR 219.21 - Authority, purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... amended by the Annunzio-Wylie Anti-Money Laundering Act of 1992 (Pub. L. 102-550, Title XV; 106 Stat. 3672... recordkeeping and reporting requirements will assist in the prosecution of money laundering activities and are...

  10. 30 CFR 219.410 - What does this subpart contain?

    Science.gov (United States)

    2010-07-01

    ..., Louisiana, Mississippi, and Texas (collectively identified as the Gulf producing States); to eligible coastal political subdivisions within those States; and to the Land and Water Conservation Fund. Shared... coastal protection, including conservation, coastal restoration, hurricane protection, and infrastructure...

  11. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Science.gov (United States)

    2010-10-01

    ... Joint Ventures. The offeror represents, as part of its offer, that it is a joint venture that complies... Business Administration or a Private Certifier in accordance with 13 CFR part 124, subpart B. For joint... in the joint venture....

  12. 32 CFR 219.116 - General requirements for informed consent.

    Science.gov (United States)

    2010-07-01

    ... involve risks to the subject (or to the embryo or fetus, if the subject is or may become pregnant) which...) Possible changes in or alternatives to those programs or procedures; or (iv) Possible changes in methods or...

  13. 48 CFR 52.219-1 - Small Business Program Representations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Program... Classification System (NAICS) code for this acquisition is— . (2) The small business size standard is... Small Business Administration, and no material change in ownership and control, principal office,...

  14. 21 CFR 2.19 - Methods of analysis.

    Science.gov (United States)

    2010-04-01

    ... enforcement programs to utilize the methods of analysis of the AOAC INTERNATIONAL (AOAC) as published in the... reference, when available and applicable. Copies are available from the AOAC INTERNATIONAL, 481 North... AOAC method, the Commissioner will furnish a copy of the particular method, or a reference to the...

  15. Dicty_cDB: SFD219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 90353.1 sae68c10.y1 Gm-c1064 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1064-3212 5' similar to TR:...049 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1049-1199 5' similar to T...c1007 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1007-2626 5' similar to TR:O65744 O65744 GDP DISSO...TION INHIBITOR. ;, mRNA sequence. 62 4e-08 2 BI315670 |BI315670.1 saf75f12.y1 Gm-c1078 Glycine max cDNA clone GENOME SYSTEMS...sequence. 62 1e-07 2 AI437629 |AI437629.1 sa37e09.y1 Gm-c1004 Glycine max cDNA clone GENOME SYSTEMS

  16. Dicty_cDB: VFA219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available N BD092935 |BD092935.1 Methods and compositions for synthesis of long chain poly...unsaturated fatty acids in plants. 1213 0.0 3 BD082645 |BD082645.1 Methods and compositions for synthesis of... long chain polyunsaturated fatty acids. 1213 0.0 3 BD082630 |BD082630.1 Methods and compositions for synthe

  17. 47 CFR 90.219 - Use of signal boosters.

    Science.gov (United States)

    2010-10-01

    ... to operate radio systems in the frequency bands above 150 MHz may employ signal boosters at fixed... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... effective radiated power (ERP) of the unit to a maximum of 5 watts under all conditions. Class B...

  18. 48 CFR 219.7103-2 - Contracting officer responsibilities.

    Science.gov (United States)

    2010-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege... the clause at 252.232-7005, Reimbursement of Subcontractor Advance Payments—DoD Pilot Mentor-Protege Program, when a mentor firm provides advance payments to a protege firm under the Program and the...

  19. 48 CFR 1552.219-70 - Mentor-Protege Program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mentor-Protege Program... Mentor-Protege Program. As prescribed in 1519.203(a), insert the following clause: Mentor-Protege Program OCT 2000 (a) The Contractor has been approved to participate in the EPA Mentor-Protege program....

  20. 34 CFR 685.219 - Public Service Loan Forgiveness Program.

    Science.gov (United States)

    2010-07-01

    ... organization that is publicly funded and whose principal activities pertain to crime prevention, control or reduction of crime, or the enforcement of criminal law. Military service, for uniformed members of the U.S... are defined by the Bureau of Labor Statistics), public education, public library services,...

  1. 36 CFR 219.4 - Identification and consideration of issues.

    Science.gov (United States)

    2010-07-01

    ... determination, the responsible official should consider: (i) The scope, complexity, and geographic scale of... or maintenance of ecological sustainability, including maintenance or restoration of watershed function, such as water flow regimes to benefit aquatic resources, groundwater recharge, municipal...

  2. Dicty_cDB: SHH219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available cleotide Sequence of the Haemophilus influenzae Rd Genome,Fragments Thereof, and Uses Thereof. 44 9e-05 2 U3.... 44 1e-04 2 BD425742 |BD425742.1 The Nucleotide Sequence of the Haemophilus influenzae Rd Genome,Fragments Thereof, and Uses

  3. 20 CFR 219.34 - When evidence that a marriage has ended is required.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When evidence that a marriage has ended is... a marriage has ended is required. Evidence of how a previous marriage ended may be required to determine whether a later marriage is valid. If a widow or widower remarried after the employee's death...

  4. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

    DEFF Research Database (Denmark)

    Kocerha, Jannet; Faghihi, Mohammad Ali; Lopez-Toledano, Miguel A

    2009-01-01

    N-methyl-D-aspartate (NMDA) glutamate receptors are regulators of fast neurotransmission and synaptic plasticity in the brain. Disruption of NMDA-mediated glutamate signaling has been linked to behavioral deficits displayed in psychiatric disorders such as schizophrenia. Recently, noncoding RNA m...

  5. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Science.gov (United States)

    2010-10-01

    ..., which are small businesses, veteran-owned small businesses, service-disabled veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses, and women-owned small business concerns... providing developmental assistance to eligible small business protégé entities......

  6. 48 CFR 52.219-16 - Liquidated Damages-Subcontracting Plan.

    Science.gov (United States)

    2010-10-01

    ... clause in this contract entitled “Small Business Subcontracting Plan,” or willful or intentional action... contract entitled “Small Business Subcontracting Plan,” the Contractor shall pay the Government liquidated... following clause: Liquidated Damages—Subcontracting Plan (JAN 1999) (a) Failure to make a good faith...

  7. 48 CFR 219.202-5 - Data collection and reporting requirements.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies... price by the low responsive offer. (3) For partial small business set-asides with preferential... departments and agencies. Reports must include— (i) Justification for failure to meet goals established by...

  8. 48 CFR 1552.219-71 - Procedures for Participation in the EPA Mentor-Protege Program.

    Science.gov (United States)

    2010-10-01

    ... Procurement Operations Division (CPOD-Norwood), U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, OH 45268, Telephone: (513) 487-2024 Fax: (513) 487-2004. (End of provision) ... officer after the SBA has completed any formal determinations. (e) The offeror shall submit an...

  9. 32 CFR 219.101 - To what does this policy apply?

    Science.gov (United States)

    2010-07-01

    ... effectiveness of or the comparison among instructional techniques, curricula, or classroom management methods...), survey procedures, interview procedures or observation of public behavior, unless: (i) Information... subjects' financial standing, employability, or reputation. (3) Research involving the use of educational...

  10. SUBTASK 2.19 – OPERATIONAL FLEXIBILITY OF CO2 TRANSPORT AND STORAGE

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Melanie; Schlasner, Steven; Sorensen, James; Hamling, John

    2014-12-31

    Carbon dioxide (CO2) is produced in large quantities during electricity generation and by industrial processes. These CO2 streams vary in terms of both composition and mass flow rate, sometimes substantially. The impact of a varying CO2 stream on pipeline and storage operation is not fully understood in terms of either operability or infrastructure robustness. This study was performed to summarize basic background from the literature on the topic of operational flexibility of CO2 transport and storage, but the primary focus was on compiling real-world lessons learned about flexible operation of CO2 pipelines and storage from both large-scale field demonstrations and commercial operating experience. Modeling and pilot-scale results of research in this area were included to illustrate some of the questions that exist relative to operation of carbon capture and storage (CCS) projects with variable CO2 streams. It is hoped that this report’s real-world findings provide readers with useful information on the topic of transport and storage of variable CO2 streams. The real-world results were obtained from two sources. The first source consisted of five full-scale, commercial transport–storage projects: Sleipner, Snøhvit, In Salah, Weyburn, and Illinois Basin–Decatur. These scenarios were reviewed to determine the information that is available about CO2 stream variability/intermittency on these demonstration-scale projects. The five projects all experienced mass flow variability or an interruption in flow. In each case, pipeline and/or injection engineers were able to accommodate any issues that arose. Significant variability in composition has not been an issue at these five sites. The second source of real- world results was telephone interviews conducted with experts in CO2 pipeline transport, injection, and storage during which commercial anecdotal information was acquired to augment that found during the literature search of the five full-scale projects. The experts represented a range of disciplines and hailed from North America and Europe. Major findings of the study are that compression and transport of CO2 for enhanced oil recovery (EOR) purposes in the United States has shown that impurities are not likely to cause transport problems if CO2 stream composition standards are maintained and pressures are kept at 10.3 MPa or higher. Cyclic, or otherwise intermittent, CO2 supplies historically have not impacted in-field distribution pipeline networks, wellbore integrity, or reservoir conditions. The U.S. EOR industry has demonstrated that it is possible to adapt to variability and intermittency in CO2 supply through flexible operation of the pipeline and geologic storage facility. This CO2 transport and injection experience represents knowledge that can be applied in future CCS projects. A number of gaps in knowledge were identified that may benefit from future research and development, further enhancing the possibility for widespread application of CCS. This project was funded through the Energy & Environmental Research Center–U.S. Department of Energy Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FC26-08NT43291. Nonfederal funding was provided by the IEA Greenhouse Gas R&D Programme.

  11. 49 CFR Appendix C to Part 219 - Post-Accident Testing Specimen Collection

    Science.gov (United States)

    2010-10-01

    .... After requiring the employee to wash his/her hands, the collector should escort the employee directly to... material (soap, etc.) that could be used to adulterate the specimen, the collector should monitor the... proceed as follows: e. Unwrap the collection cup in the employee's presence and hand it to the employee...

  12. Calibration of ground-based lidar instrument WLS7-219

    DEFF Research Database (Denmark)

    Gómez Arranz, Paula; Wagner, Rozenn

    This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbine at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement uncertaint......This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbine at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement...... uncertainties provided by measurement standard and corresponding lidar wind speed indications with associated measurement uncertainties. The lidar calibration concerns the 10 minute mean wind speed measurements. The comparison of the lidar measurements of the wind direction with that from wind vanes...

  13. 29 CFR 778.219 - Pay for foregoing holidays and vacations.

    Science.gov (United States)

    2010-07-01

    ... he is owed an additional $25 as overtime premium (additional half-time) for the 10 hours in excess of... sum as vacation pay. This is a matter of private contract between the parties who may agree that... additional $25 as overtime premium (additional half-time) for the 10 hours in excess of 40. His regular...

  14. 48 CFR 1852.219-84 - Limitation of the principal investigator-STTR program.

    Science.gov (United States)

    2010-10-01

    ... clause is with the small business concern (SBC)/Contractor or the research institution (RI). Primary... SBC/Contractor or RI. (b) The PI is considered to be key personnel in the performance of this contract. The SBC/Contractor, whether or not the employer of the PI, shall exercise primary management...

  15. 49 CFR 219.201 - Events for which testing is required.

    Science.gov (United States)

    2010-10-01

    ... representative exercises good faith judgement in making the required determinations. (ii) The railroad... made, and the person making the decision. (iv) Any estimates of railroad property damage made by... not) in making the decision whether testing is required, subject to the same requirement that...

  16. 7 CFR 2.19 - Under Secretary for Food, Nutrition, and Consumer Services.

    Science.gov (United States)

    2010-01-01

    ..., Extension, and Teaching Policy Act of 1977 (7 U.S.C. 3318). (4) Related to committee management. Establish... information. (i) Develop techniques and equipment to assist consumers in the home and in institutions in.... (iii) Develop suitable and safe preparation and management procedures to retain nutritional and...

  17. 20 CFR 219.21 - Types of evidence to prove age.

    Science.gov (United States)

    2010-04-01

    ...) Selective service registration record. (9) Census record. (10) School record. (11) Vaccination record. (12... registration of birth made before age 5. (b) Other evidence of age. If an individual cannot obtain...

  18. 48 CFR 1052.219-70 - SF 294 and SF 295 Reporting.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false SF 294 and SF 295... SF 294 and SF 295 Reporting. Per DTAR 1019.708-70(a), insert the following clause: SF 294 and SF 295... Small Business Subcontracting Plan” in Section I and the contract schedule, SF 294 and SF 295...

  19. 2-[1-(9-Anthrylmethyl-1H-pyrazol-3-yl]pyridine

    Directory of Open Access Journals (Sweden)

    Shi-Lu Zhang

    2009-11-01

    Full Text Available The title compound, C23H17N3, can be used in coordination chemistry. The anthracene ring makes dihedral angles of 86.08 (5 and 76.63 (6°, respectively, with the pyridine and pyrazole rings. The dihedral angle between the pyrazole and pyrimidine rings is 11.79 (7°. In the structure, weak intermolecular C—H...N hydrogen bonds are observed.

  20. 49 CFR 219.4 - Recognition of a foreign railroad's workplace testing program.

    Science.gov (United States)

    2010-10-01

    ... policy dealing with co-worker and self-reporting of alcohol and drug abuse problems; (iii) Random drug... the following methods: (i) Federal eRulemaking Portal: http://www.regulations.gov. Follow the... will be posted without change to http://www.regulations.gov including any personal information provided...

  1. 48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

    Science.gov (United States)

    2010-10-01

    ... subcontracting goal. (e) A mentor firm, under the Pilot Mentor-Protege Program established under Section 831 of... awarded— (1) Protege firms which are qualified organizations employing the severely handicapped; and (2) Former protege firms that meet the criteria in Section 831(g)(4) of Pub. L. 101-510. (f) The master...

  2. 48 CFR 952.219-70 - DOE Mentor-Protege program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE Mentor-Protege program...-Protege program. In accordance with 919.7014 insert the following provision in applicable solicitations. DOE Mentor-Protege Program (MAY 2000) The Department of Energy has established a...

  3. 48 CFR 52.219-18 - Notification of Competition Limited to Eligible 8(a) Concerns.

    Science.gov (United States)

    2010-10-01

    ... the acquisition is for a product in a class for which the Small Business Administration has determined... Eligible 8(a) Concerns (JUN 2003) (a) Offers are solicited only from small business concerns expressly certified by the Small Business Administration (SBA) for participation in the SBA's 8(a) Program and...

  4. 219 Enumah et al., Afr J Tradit Complement Altern Med. (2016) 13(3 ...

    African Journals Online (AJOL)

    Wolfe Street Baltimore, MD 21287, USA, 2Ifakara Health Institute, P.O. Box 74, Bagamoyo, Tanzania, 323- ..... So I went and took my drugs properly, then just when the medicines…were about to finish the ... tuberculosis are 100, then keep them 100. .... General Hospital is one of the top hospitals in Kenya and serves a large ...

  5. Codon 219 polymorphism of PRNP in healthy caucasians and Creutzfeldt-Jakob disease patients

    Energy Technology Data Exchange (ETDEWEB)

    Petraroli, R.; Pocchiari, M. [Instituto Superiore di Sanita, Rome (Italy)

    1996-04-01

    A number of point and insert mutations of the PrP gene (PRNP) have been linked to familial Creutzfeldt-Jakob disease (CJD) and Gerstmann-Straussler-Scheinker disease (GSS). Moreover, the methionine/valine homozygosity at the polymorphic codon 129 of PRNP may cause a predisposition to sporadic and iatrogenic CJD or may control the age at onset of familial cases carrying either the 144-bp insertion or codon 178, codon 198, and codon 210 pathogenic mutations in PRNP. In addition, the association of methionine or valine at codon 129 and the point mutation at codon 178 on the same allele seem to play an important role in determining either fatal familial insomnia or CJD. However, it is noteworthy that a relationship between codon 129 polymorphism and accelerated pathogenesis (early age at onset or shorter duration of the disease) has not been seen in familial CJD patients with codon 200 mutation or in GSS patients with codon 102 mutation, arguing that other, as yet unidentified, gene products or environmental factors, or both, may influence the clinical expression of these diseases. 17 refs.

  6. 20 CFR 219.37 - Evidence of natural parent or child relationship.

    Science.gov (United States)

    2010-04-01

    ... employee, preferred evidence of the ralationship is a copy of the employee's public or religious birth record. If the claimant is the natural child of the employee, preferred evidence of the relationship is a... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of natural parent or child...

  7. (sfragís) and its metaphorical testimonial presence in 2 Timothy 2:19

    African Journals Online (AJOL)

    2010-10-12

    Oct 12, 2010 ... As starting point, attention was given to the concept of 'seal' through ..... beyond, religion was the Roman State and, at the same time, any priest .... Medieval Middle East (NMC 369H)', Ancient Near Eastern Seals, viewed 13.

  8. 219 Enumah et al., Afr J Tradit Complement Altern Med. (2016) 13(3 ...

    African Journals Online (AJOL)

    Key words: traditional healing, complementary medicine, spiritual healing, Kenya .... was sought to limit the influence of factors specific to locales outside of Mombasa. .... that involves the massaging of the woman's belly in order to reorient the fetus “in ... risk in some ways, health-wise. ...... University of Virginia Press, 1997.

  9. 48 CFR 52.219-11 - Special 8(a) Contract Conditions.

    Science.gov (United States)

    2010-10-01

    ... (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 52... terminated either in whole or in part without cost to either party. (c) Except for novation agreements and... control of the concern. (End of clause) ...

  10. 48 CFR 52.219-3 - Notice of total HUBZone set-aside.

    Science.gov (United States)

    2010-10-01

    ... performance of the contract, in the case of a contract for— (1) Services (except construction), at least 50... manufacturer concerns. This paragraph does not apply in connection with construction or service contracts. (End... REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and...

  11. Yeast Interacting Proteins Database: YPL031C, YPL219W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ting the cellular response to nutrient levels and environmental conditions and progression through the cell ...e cellular response to nutrient levels and environmental conditions and progression through the cell cycle R

  12. Calibration of ground-based Lidar instrument WLS7-219

    DEFF Research Database (Denmark)

    Yordanova, Ginka; Gómez Arranz, Paula

    This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbines at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement uncertain......This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbines at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement...... uncertainties provided by measurement standard and corresponding lidar wind speed indications with associated measurement uncertainties. The lidar calibration concerns the 10 minute mean wind speed measurements. The comparison of the lidar measurements of the wind direction with that from wind vanes...

  13. 28 CFR 2.219 - Maximum terms of imprisonment and supervised release.

    Science.gov (United States)

    2010-07-01

    ..., SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS District of Columbia... supervised release that the sentencing court was authorized to impose for the offense of conviction, less the... from the sentencing judge certifying that the defendant is a sex offender. (3) If the...

  14. Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation

    Institute of Scientific and Technical Information of China (English)

    Anna Pick Kiong LING; Ying Chian UNG; Sobri HUSSEIN; Abdul Rahim HARUN; Atsushi TANAKA; Hase YOSHIHIRO

    2013-01-01

    Objective:Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological and biochemical responses of Oryza sativa toward different doses of carbon ion beam irradiation. Methods: In this study, the dry seeds of O. sativa were irradiated at 0, 20, 40, 60, 80, 100, and 120 Gy, fol owed by in-vitro germination under control ed conditions. Morphological and biochemical studies were conducted to investigate the morphological and physiological responses of O. sativa towards ion beam irradiation. Results: The study demonstrated that low doses (10 Gy) of ion beam have a stimulating effect on the height, root length, and fresh weight of the plantlets but not on the number of leaves. Meanwhile, doses higher than 10 Gy caused reductions in all the morphological parameters studied as compared to the control samples. The highest total soluble protein content [(2.11±0.47) mg/g FW] was observed in plantlets irradiated at 20 Gy. All irradiated plantlets were found to have 0.85%to 58.32%higher specific activity of peroxidase as compared to the control samples. The present study also revealed that low doses of ion beam (10 and 20 Gy) had negligible effect on the total chlorophyl content of O. sativa plantlets while 40 Gy had a stimulating effect on the chlorophyll content. Plantlets irradiated between 40 to 120 Gy were shown to be 0.38%to 9.98%higher in total soluble nitrogen content which, however, was not significantly different from the control samples. Conclusions:Carbon ion beam irradiation administered at low to moderate doses of 10 to 40 Gy may induce O. sativa mutants with superior characteristics.

  15. Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation*

    Science.gov (United States)

    Ling, Anna Pick Kiong; Ung, Ying Chian; Hussein, Sobri; Harun, Abdul Rahim; Tanaka, Atsushi; Yoshihiro, Hase

    2013-01-01

    Objective: Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological and biochemical responses of Oryza sativa toward different doses of carbon ion beam irradiation. Methods: In this study, the dry seeds of O. sativa were irradiated at 0, 20, 40, 60, 80, 100, and 120 Gy, followed by in-vitro germination under controlled conditions. Morphological and biochemical studies were conducted to investigate the morphological and physiological responses of O. sativa towards ion beam irradiation. Results: The study demonstrated that low doses (10 Gy) of ion beam have a stimulating effect on the height, root length, and fresh weight of the plantlets but not on the number of leaves. Meanwhile, doses higher than 10 Gy caused reductions in all the morphological parameters studied as compared to the control samples. The highest total soluble protein content [(2.11±0.47) mg/g FW] was observed in plantlets irradiated at 20 Gy. All irradiated plantlets were found to have 0.85% to 58.32% higher specific activity of peroxidase as compared to the control samples. The present study also revealed that low doses of ion beam (10 and 20 Gy) had negligible effect on the total chlorophyll content of O. sativa plantlets while 40 Gy had a stimulating effect on the chlorophyll content. Plantlets irradiated between 40 to 120 Gy were shown to be 0.38% to 9.98% higher in total soluble nitrogen content which, however, was not significantly different from the control samples. Conclusions: Carbon ion beam irradiation administered at low to moderate doses of 10 to 40 Gy may induce O. sativa mutants with superior characteristics. PMID:24302713

  16. 36 CFR 219.11 - Monitoring and evaluation for adaptive management.

    Science.gov (United States)

    2010-07-01

    ... reliable information regarding social and economic sustainability. (b) Monitoring of site-specific actions... OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework... diversity and species diversity in providing reliable information regarding ecological sustainability. (2...

  17. ПC-219车辆轮对轴承圈过盈量检测仪%Interference tester for the bearing rings on wheelsets of ПC - 219 railcars

    Institute of Scientific and Technical Information of China (English)

    胥金荣

    2006-01-01

      与铁路行车安全紧密相关的问题之一,就是缺少用于批量检测轴承内圈在轮对车轴上套装可靠过盈量的仪器.目前所使用的常规方法,其可靠性较低.因为它是以套装之前测量轴承圈和轮对车轴的直径为依据的,并没有考虑到轴承圈的加热和与车轴的机械连接,这些随机工艺过程中的许多因素对套装质量将产生较大的影响.

  18. La Desercion Escolar en los Niveles de Sexto y Noveno Grado: Una Comparacion Entre Zonas Rurales y Urbanas. Boletin 219 (The Educational Desertion in the 6th and 9th Grades: A Comparison Between Rural and Urban Zones. Bulletin 219).

    Science.gov (United States)

    Lopez, Maria I. Hernandez; And Others

    In 1962 and again in 1965, a group of sixth and ninth grade students in selected schools in four Puerto Rican communities were interviewed to investigate the factors influencing students' decision to withdraw from school before completing twelfth grade and to identify some characteristics of dropouts. Of 616 students interviewed in 1962, 20.9% of…

  19. La Desercion Escolar en los Niveles de Sexto y Noveno Grado: Una Comparacion Entre Zonas Rurales y Urbanas. Boletin 219 (The Educational Desertion in the 6th and 9th Grades: A Comparison Between Rural and Urban Zones. Bulletin 219).

    Science.gov (United States)

    Lopez, Maria I. Hernandez; And Others

    In 1962 and again in 1965, a group of sixth and ninth grade students in selected schools in four Puerto Rican communities were interviewed to investigate the factors influencing students' decision to withdraw from school before completing twelfth grade and to identify some characteristics of dropouts. Of 616 students interviewed in 1962, 20.9% of…

  20. Lithium-vanadium advanced blanket development. ITER final report on U.S. contribution: Task T219/T220

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.L.; Mattas, R.F. [comps.

    1997-07-01

    The objective of this task is to develop the required data base and demonstrate the performance of a liquid lithium-vanadium advanced blanket design. The task has two main activities related to vanadium structural material and liquid lithium system developments. The vanadium alloy development activity included four subtasks: (1.1) baseline mechanical properties of non irradiated base metal and weld metal joints; (1.2) compatibility with liquid lithium; (1.3) material irradiation tests; and (1.4) development of material manufacturing and joining methods. The lithium blanket technology activity included four subtasks: (2.1) electrical insulation development and testing for liquid metal systems; (2.2) MHD pressure drop and heat transfer study for self-cooled liquid metal systems; (2.3) chemistry of liquid lithium; and (2.4) design, fabrication and testing of ITER relevant size blanket mockups. A summary of the progress and results obtained during the period 1995 and 1996 in each of the subtask areas is presented in this report.

  1. 75 FR 25844 - Class Deviation From FAR 52.219-7, Notice of Partial Small Business Set-Aside

    Science.gov (United States)

    2010-05-10

    ... portion at a price higher than its offer price under the non-set-aside portion. The proposed revisions are... DOCUMENT. I237.06 NOTICE OF PARTIAL SMALL BUSINESS SET-ASIDE (DEVIATION) (DESC) (a) DEFINITION. Small... negotiated as to price and an evaluation will be made as though there were no set-aside. (4) For the purposes...

  2. Jürgen Jaspers: De klank van de stad. Stedelijke meertaligheid en interculturele communicatie (red.). Leuven, ACCO, 2009. 219 blz.

    NARCIS (Netherlands)

    Nortier, J.M.

    2010-01-01

    De klank van de stad is geschreven naar aanleiding van een congres over hetzelfde thema, stedelijke meertaligheid (maart 2008, Antwerpen). De auteurs waren in meerderheid sprekers bij het congres die hun presentaties in soms wat gewijzigde vorm hebben opgeschreven. Iedereen die wel eens te maken hee

  3. Crystallization and preliminary crystallographic analysis of the catechol 2,3-dioxygenase PheB from Bacillus stearothermophilus BR219

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, Keisuke; Matsufuzi, Kazuki; Ohnuma, Hiroaki [Department of Material Chemistry, Asahikawa National College of Technology, 2-2-1-6 Shunko-dai, Asahikawa, Hokkaido 071-8142 (Japan); Senda, Miki [Japan Biological Information Research Center (JBIRC), Japan Biological Informatics Consortium (JBIC), 2-42 Aomi, Koto-ku, Tokyo 135-0064 (Japan); Fukuda, Masao [Department of Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata 940-2188 (Japan); Senda, Toshiya, E-mail: tsenda@jbirc.aist.go.jp [Biological Information Research Center (BIRC), National Institute of Advanced Industrial Science and Technology (AIST), 2-42 Aomi, Koto-ku, Tokyo (Japan); Department of Material Chemistry, Asahikawa National College of Technology, 2-2-1-6 Shunko-dai, Asahikawa, Hokkaido 071-8142 (Japan)

    2006-02-01

    PheB, an extradiol-cleaving catecholic dioxygenase, was crystallized by the hanging-drop vapour-diffusion method using PEG 4000 as a precipitant. The crystal belongs to the orthorhombic system, space group P2{sub 1}2{sub 1}2{sub 1}, and diffracts to 2.3 Å resolution. Class II extradiol-cleaving catecholic dioxygenase, a key enzyme of aromatic compound degradation in bacteria, cleaves the aromatic ring of catechol by adding two O atoms. PheB is one of the class II extradiol-cleaving catecholic dioxygenases and shows a high substrate specificity for catechol derivatives, which have one aromatic ring. In order to reveal the mechanism of the substrate specificity of PheB, PheB has been crystallized by the hanging-drop vapour-diffusion method using PEG 4000 as a precipitant. The space group of the obtained crystal was P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 65.5, b = 119.2, c = 158.7 Å. The crystal diffracted to 2.3 Å resolution.

  4. Rubric for Evaluating Reading/Language Arts Instructional Materials for Kindergarten to Grade 5. REL 2017-219

    Science.gov (United States)

    Foorman, Barbara R.; Smith, Kevin G.; Kosanovich, Marcia L.

    2017-01-01

    The implementation of effective instructional materials, such as a core reading program, by a qualified teacher is an important part of improving students' reading achievement. But selecting those instructional materials can be time-consuming. Regional Educational Laboratory (REL) Southeast created this rubric for evaluating reading/language arts…

  5. 48 CFR 852.219-11 - VA notice of total veteran-owned small business set-aside.

    Science.gov (United States)

    2010-10-01

    ...) A joint venture may be considered a veteran-owned small business concern if: (1) At least one member of the joint venture is a veteran-owned small business concern, and makes the following... corresponding to the NAICS code assigned to the procurement; (3) The joint venture meets the requirements...

  6. 77 FR 40494 - Procedures for the Handling of Retaliation Complaints Under Section 219 of the Consumer Product...

    Science.gov (United States)

    2012-07-10

    ... Flammable Fabrics Act (15 U.S.C. 1191 et seq.), the Poison Prevention Packaging Act (15 U.S.C. 1471 et seq... provided in the whistleblower statutes are directory. Failure to complete the investigation or issue a... Associate Solicitor for Fair Labor Standards, the failure to serve copies of the objections on the other...

  7. 75 FR 53533 - Procedures for the Handling of Retaliation Complaints Under Section 219 of the Consumer Product...

    Science.gov (United States)

    2010-08-31

    ... privileges associated with his or her employment; and provide compensatory damages to the complainant, as... economy, productivity, competition, jobs, the environment, public health or safety, or State, local, or... vehicle equipment (as defined by 49 U.S.C. 30102(a)(6) and (7)); (iv) Pesticides (as defined by the...

  8. Characterization of Nitrogen Uptake Pattern in Malaysian Rice MR219 at Different Growth Stages Using 15N Isotope

    Directory of Open Access Journals (Sweden)

    Mohammad Mu’az Hashim

    2015-09-01

    Full Text Available Nitrogen (N use efficiency is usually less than 50%, and it remains a major problem in rice cultivation. Controlled release fertilizer (CRF technology is one of the well-known efforts to overcome this problem. The efficiency of CRF, however, is very much dependent on the timing of nutrient release. This study was conducted to determine the precise time of N uptake by rice as a guideline to develop efficient CRF. Fertilizer N uptake by rice at different growth stages was investigated by using 15N isotopic technique. Rice was planted in pots, with 15N urea as N source at the rate of 120 kg/hm2. Potassium and phosphorus were applied at the same rate of 50 kg/hm2. Standard agronomic practices were employed throughout the growing periods. Rice plants were harvested every two weeks until maturation at the 14th week and analyzed for total N and 15N content. Nitrogen derived from fertilizer was calculated. Total N uptake in plants consistently increased until the 11th week. After that, it started to plateau and finally declined. Moreover, N utilization by rice plants peaked at 50%, which occurred during the 11th week after transplanting. N derived from fertilizer in rice plants were in the range of 18.7% to 40.0% in all plant tissues. The remaining N was derived from soil. Based on this study, N release from CRF should complete by the 11th week after planting to ensure the maximum fertilizer N uptake by rice plants. Efficient CRF should contribute to higher N derived from fertilizer which also resultedin a higher total N uptake by rice plants, increasing the potential of rice to produce higher yield while at the same time of reducing loss.

  9. 78 FR 35567 - Safety Zone; Lower Mississippi River, Mile Marker 219 to Mile Marker 229, in the Vicinity of Port...

    Science.gov (United States)

    2013-06-13

    ...: If you have questions on this rule, call or email Lieutenant Christopher Norton, Coast Guard Marine Safety Unit Baton Rouge; telephone (225) 298-5400, email Christopher.R.Norton@uscg.mil . If you have... Norton, Marine Safety Unit Baton Rouge, at (225) 298-5400 or Christopher.R.Norton@uscg.mil ....

  10. 75 FR 32773 - Auction of 218-219 MHz Service and Phase II 220 MHz Service Licenses Scheduled for December 7...

    Science.gov (United States)

    2010-06-09

    ... format documents, sign language interpreters, CART, etc.) by e-mail: FCC504@fcc.gov or phone: 202-418... Commission has authorized certain site-based, low power operations on a secondary basis in the 216-220 MHz..., the service rules permit a variety of fixed, mobile, and paging services, though the opportunities...

  11. Nelly Hanna : Making Big Money in 1600. The Life and Time of Isma'il Abu Taqiyya, Egyptian Merchant, Syracuse University Press, Syracuse, New York, 1998, 219 p.

    Directory of Open Access Journals (Sweden)

    Daniel Panzac

    2009-01-01

    Full Text Available Nelly Hanna est professeur associé à l'Université américaine du Caire et spécialiste d'Histoire de l'époque ottomane de l'Égypte. Son œuvre s'inscrit dans le courant actuel de la recherche historique qui s'efforce, avec succès, de montrer que la période ottomane (xvie-xviiie siècles n'est pas, pour l'Égypte, aussi calamiteuse et régressive que l'on aurait trop tendance à l'admettre face à la glorieuse période précédente, celle des Mamelouks qui régnèrent du milieu du xiiie à la fin du xve si...

  12. Reliability and measurement error of frontal and horizontal 3D spinal motion parameters in 219 patients with chronic low back pain

    DEFF Research Database (Denmark)

    Harsted, Steen; Mieritz, Rune M; Bronfort, Gert

    2016-01-01

    mechanical LBP, classified as either Quebec Task Force group 1, 2, 3 or 4 were included, and kinematics of the lumbar spine were sampled during standardized spinal lateral flexion and rotation motion using a 6-df instrumented spatial linkage system. Test-retest reliability and measurement error were...... a stable pain level between tests, and were male. ROM measurements were more reliable in patients with a BMI higher than 30, and measurements on patients with LBP and leg pain showed higher reliability and smaller measurement error in all parameters except for the jerk index. CONCLUSION: Frontal plane......BACKGROUND: In order for measurements to be clinically useful, data on psychometric conditions such as reliability should be available in the population for which the measurements are intended to be used. This study comprises a test-retest design separated by 7 to 14 days, and evaluates the intra...

  13. P2-19: The Effect of item Repetition on Item-Context Association Depends on the Prior Exposure of Items

    Directory of Open Access Journals (Sweden)

    Hongmi Lee

    2012-10-01

    Full Text Available Previous studies have reported conflicting findings on whether item repetition has beneficial or detrimental effects on source memory. To reconcile such contradictions, we investigated whether the degree of pre-exposure of items can be a potential modulating factor. The experimental procedures spanned two consecutive days. On Day 1, participants were exposed to a set of unfamiliar faces. On Day 2, the same faces presented on the previous day were used again in half of the participants, whereas novel faces were used for the other half. Day 2 procedures consisted of three successive phases: item repetition, source association, and source memory test. In the item repetition phase, half of the face stimuli were repeatedly presented while participants were making male/female judgments. During the source association phase, both the repeated and the unrepeated faces appeared in one of the four locations on the screen. Finally, participants were tested on the location in which a given face was presented during the previous phase and reported the confidence of their memory. Source memory accuracy was measured as the percentage of correct non-guess trials. As results, we found a significant interaction between prior exposure and repetition. Repetition impaired source memory when the items had been pre-exposed on Day 1, while it led to greater accuracy in novel ones. These results show that pre-experimental exposure can modulate the effects of repetition on associative binding between an item and its contextual information, suggesting that pre-existing representation and novelty signal interact to form new episodic memory.

  14. Investigations of the in Planta Expression of Active Cellobiohydrolase I: Cooperative Research and Development Final Report, CRADA Number CRD-07-219

    Energy Technology Data Exchange (ETDEWEB)

    Himmel, M.

    2011-02-01

    It was the purpose of this project to determine if cellulases produced in transgenic plants could effectively be utilized in the production of ethanol and other feedstock chemicals from lignocellulosic substrates.

  15. Improving Lowland Rice (O. sativa L. cv. MR219) Plant Growth Variables, Nutrients Uptake, and Nutrients Recovery Using Crude Humic Substances.

    Science.gov (United States)

    Palanivell, Perumal; Ahmed, Osumanu Haruna; Ab Majid, Nik Muhamad; Jalloh, Mohamadu Boyie; Susilawati, Kasim

    2015-01-01

    High cation exchange capacity and organic matter content of crude humic substances from compost could be exploited to reduce ammonia loss from urea and to as well improve rice growth and soil chemical properties for efficient nutrients utilization in lowland rice cultivation. Close-dynamic air flow system was used to determine the effects of crude humic substances on ammonia volatilization. A pot experiment was conducted to determine the effects of crude humic substances on rice plant growth, nutrients uptake, nutrients recovery, and soil chemical properties using an acid soil mixed with three rates of crude humic substances (20, 40, and 60 g pot(-1)). Standard procedures were used to evaluate rice plant dry matter production, nutrients uptake, nutrients recovery, and soil chemical properties. Application of crude humic substances increased ammonia volatilization. However, the lowest rate of crude humic substances (20 g pot(-1)) significantly improved total dry matter, nutrients uptake, nutrients recovery, and soil nutrients availability compared with crude humic substances (40 and 60 g pot(-1)) and the normal fertilization. Apart from improving growth of rice plants, crude humic substances can be used to ameliorate acid soils in rice cultivation. The findings of this study are being validated in our ongoing field trials.

  16. Improving Lowland Rice (O. sativa L. cv. MR219 Plant Growth Variables, Nutrients Uptake, and Nutrients Recovery Using Crude Humic Substances

    Directory of Open Access Journals (Sweden)

    Perumal Palanivell

    2015-01-01

    Full Text Available High cation exchange capacity and organic matter content of crude humic substances from compost could be exploited to reduce ammonia loss from urea and to as well improve rice growth and soil chemical properties for efficient nutrients utilization in lowland rice cultivation. Close-dynamic air flow system was used to determine the effects of crude humic substances on ammonia volatilization. A pot experiment was conducted to determine the effects of crude humic substances on rice plant growth, nutrients uptake, nutrients recovery, and soil chemical properties using an acid soil mixed with three rates of crude humic substances (20, 40, and 60 g pot−1. Standard procedures were used to evaluate rice plant dry matter production, nutrients uptake, nutrients recovery, and soil chemical properties. Application of crude humic substances increased ammonia volatilization. However, the lowest rate of crude humic substances (20 g pot−1 significantly improved total dry matter, nutrients uptake, nutrients recovery, and soil nutrients availability compared with crude humic substances (40 and 60 g pot−1 and the normal fertilization. Apart from improving growth of rice plants, crude humic substances can be used to ameliorate acid soils in rice cultivation. The findings of this study are being validated in our ongoing field trials.

  17. 48 CFR 852.219-10 - VA Notice of total service-disabled veteran-owned small business set-aside.

    Science.gov (United States)

    2010-10-01

    ...; and (iv) The business has been verified for ownership and control and is so listed in the Vendor... business concern under the North American Industry Classification Systems (NAICS) code assigned to the... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false VA Notice of total...

  18. 77 FR 62316 - Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195; Decision and Order

    Science.gov (United States)

    2012-10-12

    ... well as some of the historical store-entered records from the past.'' Id. at 1246. Moreover, the... Soma [the branded version of carisoprodol] [is] being used by patients abusing prescriptions drugs...

  19. SU-E-J-219: A Dixon Based Pseudo-CT Generation Method for MR-Only Radiotherapy Treatment Planning of the Pelvis and Head and Neck

    Energy Technology Data Exchange (ETDEWEB)

    Maspero, M.; Meijer, G.J.; Lagendijk, J.J.W.; Berg, C.A.T. van den [Department of Radiotherapy, UMC Utrecht (Netherlands); Seevinck, P.R.; Viergever, M.A. [Image Science Institute, UMC Utrecht (Netherlands)

    2015-06-15

    Purpose: To develop an image processing method for MRI-based generation of electron density maps, known as pseudo-CT (pCT), without usage of model- or atlas-based segmentation, and to evaluate the method in the pelvic and head-neck region against CT. Methods: CT and MRI scans were obtained from the pelvic region of four patients in supine position using a flat table top only for CT. Stratified CT maps were generated by classifying each voxel based on HU ranges into one of four classes: air, adipose tissue, soft tissue or bone.A hierarchical region-selective algorithm, based on automatic thresholding and clustering, was used to classify tissues from MR Dixon reconstructed fat, In-Phase (IP) and Opposed-Phase (OP) images. First, a body mask was obtained by thresholding the IP image. Subsequently, an automatic threshold on the Dixon fat image differentiated soft and adipose tissue. K-means clustering on IP and OP images resulted in a mask that, via a connected neighborhood analysis, allowing the user to select the components corresponding to bone structures.The pCT was estimated through assignment of bulk HU to the tissue classes. Bone-only Digital Reconstructed Radiographs (DRR) were generated as well. The pCT images were rigidly registered to the stratified CT to allow a volumetric and voxelwise comparison. Moreover, pCTs were also calculated within the head-neck region in two volunteers using the same pipeline. Results: The volumetric comparison resulted in differences <1% for each tissue class. A voxelwise comparison showed a good classification, ranging from 64% to 98%. The primary misclassified classes were adipose/soft tissue and bone/soft tissue. As the patients have been imaged on different table tops, part of the misclassification error can be explained by misregistration. Conclusion: The proposed approach does not rely on an anatomy model providing the flexibility to successfully generate the pCT in two different body sites. This research is founded by ZonMw IMDI Programme, project name: “RASOR sharp: MRI based radiotherapy planning using a single MRI sequence”, project number: 10-104003010.

  20. Proceedings of US/Japan workshop, Q219 on high heat flux components and plasma surface interactions for next fusion devices

    Energy Technology Data Exchange (ETDEWEB)

    Ulrickson, M.A.; Stevens, P.L.; Hino, T.; Hirohata, Y. [eds.

    1996-12-01

    This report contains the viewgraphs from the proceedings of US/Japan Workshop on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices. Some of the general topics covered by this report are: PFC/PSI in tokamak and helical devices; development of high heat flux components; PSIS and plasma facing materials;tritium; and material damage.

  1. The Beaverdam Group: Archaeological Investigations at 9EB92, 9EB207, 9EB208 and 9EB219 Richard B. Russell Multiple Resource Area, Elbert County, Georgia.

    Science.gov (United States)

    1984-01-01

    36 Laboratory Methods ........... .................. ..... .. 37 -- Lithic Analysis ................................... 37...historic activity. The majority of the historic items were expended shotgun shells and discarded cans. Lithic Analysis The majority of artifacts...recovered from the Beaverdam Group sites consists of lithic material, most of which is crudely worked. Lithic analysis proceeded on the basis of two

  2. Utilização de promotores de crescimento para frangos de corte em rações fareladas e peletizadas - DOI: 10.4025/actascianimsci.v29i2.219 Utilization of growth promoter for broiler chickens in mashed and pellets diets - DOI: 10.4025/actascianimsci.v29i2.219

    Directory of Open Access Journals (Sweden)

    Mathias Djalma Appelt

    2007-11-01

    Full Text Available Avaliou-se o efeito da suplementação de dietas com diferentes promotores de crescimento sobre o desempenho e rendimento de carcaça de frangos de corte de 1 a 42 dias de idade. Foram utilizados 576 pintos da linhagem Cobb 500, machos, alojados em cama reutilizada, distribuídos em um delineamento inteiramente casualizado, em esquema fatorial 2 x 3 (forma física da ração x diferentes promotores de crescimento, totalizando 6 tratamentos, com 6 repetições e 16 aves por unidade experimental. As características de desempenho avaliadas foram ganho de peso, peso final, consumo de ração, conversão alimentar, mortalidade e o índice de eficiência produtiva. Avaliou-se também o rendimento de carcaça, bem como rendimento em cortes, coração, fígado e gordura abdominal. Os resultados obtidos demonstram não haver efeito dos tratamentos estudados sobre as características de desempenho e rendimento de carcaça.This study evaluated the supplementation effect of diets with different growth promoters on the performance and carcass yield in broilers from 1 to 42 days of age. Five hundred seventy six broilers of the Coob 500 lineage were used, all males, lodged in reused litter, allocated according to a completely randomized design in a 2 x 3 factorial scheme (physical forms of the ration x growth promoters, totalizing 6 treatments, 6 repetitions per treatment and 16 broilers per experimental unit. The performance parameters evaluated were weight gain, final weight, feed consumption, feed conversion, mortality and index productive efficiency. The carcass yield was also evaluated, as the cuts yield and percentage of abdominal fat at 42 days. The results demonstrated no effect of the treatments studied on the performance characteristics and carcass yield.

  3. 10 CFR Appendix E to Part 20 - Nationally Tracked Source Thresholds

    Science.gov (United States)

    2010-01-01

    ... Category 1(TBq) Category 1(Ci) Category 2(TBq) Category 2(Ci) Actinium-227 20 540 0.2 5.4 Americium-241 60... 2 54 Strontium-90 1,000 27,000 10 270 Thorium-228 20 540 0.2 5.4 Thorium-229 20 540 0.2 5.4...

  4. I. The metabolic properties of plutonium and allied materials

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, J.G.

    1948-05-24

    This report on the metabolic properties of plutonium and related radioactive materials presents experimental information in the following areas: radioautographic studies; tracer studies (with tables of accumulation in tissues) of actinium, radio-zirconium, technetium, radio-rubidium, radio-germanium, beryllium, and cadmium; decontamination and bone metabolism studies; and radio-chemical isolation.

  5. Monofunctionalization of Calix[4]arene Tetracarboxylic Acid at the Upper Rim with Isothiocyanate Group: First Bifunctional Chelating Agent for Alpha-Emitter Ac-225.

    Science.gov (United States)

    Chen, Xiaoyuan; Ji, Min; Fisher, Darrell R; Wai, Chien M

    1999-09-01

    A procedure is reported for synthesizing a novel, water-soluble bifunctional chelating agent derived from calix[4]arene. This chelate features tetracarboxylic acid groups at the lower rim as an actinium-225 ionophore, and an isothiocyanate functional group at the upper rim for labeling of the N-terminus of monoclonal antibodies through thiourea linkage.

  6. Comment on ;Evolution of high-pressure mafic granulites and pelitic gneisses from NE Madagascar: Tectonic implications;. Tectonophysics, 662, 219-242 (2015) by Ishwar-Kumar et al.

    Science.gov (United States)

    Goncalves, Philippe; Brandt, Sönke; Nicollet, Christian; Tucker, Robert

    2017-05-01

    Determining the possible tectonic regimes active during the Neoproterozoic is crucial for the knowledge of the evolution of the super-continent Gondwana. In Madagascar, that occupies a key position in Gondwana, there is an on-going debate regarding the location of possible suture zones and the implications in terms of paleo-geography. Recognizing high-pressure to ultra-high pressure conditions in mafic rocks is commonly viewed as a strong argument for paleo-subduction zones. Ishwar-Kumar et al. (2015) report unusual high pressure conditions (24 kbar) in Neoproterozoic to Cambrian rocks from North-Central Madagascar (Andriamena Complex). They propose a geodynamic model in which exhumation of the high pressure terranes from up to 80 km to 40 km occurred via vertical extrusion during the collision of various crustal blocks after subduction and closure of an oceanic domain during the formation of Gondwana in the late Neoproterozoic to Cambrian. We question this model and in particular the (ultra-)high pressure conditions reported, because their estimation is based on a misinterpretation of the petrography and inaccurate thermodynamic modeling for the crucial metabasite sample. The authors suggest that garnet-quartz coronas around orthopyroxene and ilmenite coexist with clinopyroxene. The postulated garnet-clinopyroxene-quartz assemblage is interpreted to document an eclogite facies overprint. However, the presence of abundant plagioclase in the sample and the lack of high jadeite content in clinopyroxene clearly refute the postulated eclogite facies conditions. According to the presented photographs clinopyroxene is part of the rock matrix. We therefore suggest that the sample represents a common two-pyroxene granulite, formed at mid- to low-pressure granulite facies conditions of > 700 °C and Madagascar, this interpretation is not justified by the data presented by Ishwar-Kumar et al. (2015).

  7. Núñez Becerra, Fernanda, La prostitución y su represión en la Ciudad de México (siglo XIX). Prácticas y representaciones, Barcelona, Gedisa Editorial, 2002, 219 p.

    OpenAIRE

    Albornoz Vásquez, María Eugenia

    2006-01-01

    La autora, de formación antropóloga y doctorada en Historia por la Universidad de Paris VII Diderot, muestra a través de este ameno ensayo la importancia crucial de la figura de la prostituta en la conformación de los modelos de ser mujer en particular y de ser familia decente, en general, en la sociedad mexicana de la segunda mitad del siglo XIX. Con un estilo desenfadado y polemizante, no exento de ironía, de juicios subjetivos (decir “representaciones aburridas de mujeres acartonadas” para...

  8. Application of solar energy to the supply of industrial process hot water: preliminary design and performance report. Volume I. Technical report. Aerotherm report TR-76-219. [For can washing at Campbell Soup Plant in Sacramento

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-10-14

    The design and performance of a solar hot water system for can washing at the Campbell Soup Plant in Sacramento, California, are presented. The collector field is located on the roof of the finished products warehouse of the Campbell Soup Sacramento plant. Water is supplied from a 3.8 cm (1/sup 1///sub 2/ in.) supply line which is located directly below an existing roof access hatch. A supply pipe will be brought up through that hatch. The water flow will then be split into two manifold lines which supply the dual rows of flat plate collectors. The preheated water from the flat plates is then passed into six sets of parallel connected concentrators. Each set consist of eight 1.83 x 3.05 m (6 x 10 foot) modules connected in series. The water from these units is gathered in a 3.8 cm (1/sup 1///sub 2/ in.) insulated pipe which transports it to the storage tank. This pipe will be attached to an existing pipe run until it reaches the can washing building. From there the pipe will follow the can washing building around to the storage tank. The storage tank is a 75,200 1 (20,000 gal) steel tank which is coated internally with a USDA approved phenolic liner. The outside of the tank is insulated. A 2.2 kw (3 hp) motor is used to pump the stored water for the tank into the can washing line. Detail drawings and descriptions of the collector field, installation, piping, controls, data acquisition equipment, and roof structure are included. Furthermore, a program schedule with equipment and manpower costs for successfully completing Phase II of this contract is included. Also included is an organization chart of the Phase II program personnel. (WHK)

  9. Petrographic atlas characterisation of aggregates regarding potential reactivity to alkalis : RILEM TC 219-ACS recommended guidance AAR-1.2, for use with the RILEM AAR-1.1 petrographic examination method

    CERN Document Server

    Ribeiro, Maria; Broekmans, Maarten; Sims, Ian

    2016-01-01

    This RILEM AAR 1.2 Atlas is complementary to the petrographic method described in RILEM AAR 1.1. It is designed and intended to assist in the identification of alkali-reactive rock types in concrete aggregate by thin-section petrography. Additional issues include: • optical thin-section petrography conforming to RILEM AAR 1.1 is considered the prime assessment method for aggregate materials, being effective regarding cost and time. Unequivocal identification of minerals in very-fine grained rock types may however require use of supplementary methods. • the atlas adheres to internationally adopted schemes for rock classification and nomenclature, as recommended in AAR 1.1. Thus, rock types are classified as igneous, sedimentary or metamorphic based upon mineral content, microstructure and texture/fabric. • in addition, the atlas identifies known alkali-reactive silica types in each rock type presented. It also identifies consistent coincidence between certain lithologies and silica types; however, it ref...

  10. RILEM recommendations for the prevention of damage by alkali-aggregate reactions in new concrete structures state-of-the-art report of the RILEM technical committee 219-ACS

    CERN Document Server

    Sims, Ian

    2016-01-01

    This book contains the full set of RILEM Recommendations which have been produced to enable engineers, specifiers and testing houses to design and produce concrete which will not suffer damage arising from alkali reactions in the concrete. There are five recommended test methods for aggregates (designated AAR-1 to AAR-5), and an overall recommendation which describes how these should be used to enable a comprehensive aggregate assessment (AAR-0). Additionally, there are two Recommended International Specifications for concrete (AAR-7.1 & 7.2) and a Preliminary International Specification for dams and other hydro structures (AAR-7.3), which describe how the aggregate assessment can be combined with other measures in the design of the concrete to produce a concrete with a minimised risk of developing damage from alkali-aggregate reactions.

  11. Posicionamentos identitários em práticas de escrita da esfera acadêmica DOI - 10.5752/P.2358-3428.2013v17n32p219

    Directory of Open Access Journals (Sweden)

    Jane Quintiliano Guimaraes Silva

    2013-07-01

    Full Text Available Em interlocução com o pressuposto de que as práticas discursivas da esfera acadêmica são espaços constitutivos de identidades, este trabalho, sob uma perspectiva discursiva, investiga os posicionamentos discursivo-enunciativos de alunos em processo de formação acadêmico-profissional em Letras, a fim de compreender os movimentos de emergência identitária desses sujeitos no trabalho da construção discursiva de seus textos. Tendo em vista não somente a organização da composicionalidade textual como também as condições de produção dos discursos, são analisados diferentes mecanismos enunciativos e discursivos (particularmente as estratégias de referência pessoal, as modalizações e o jogo de vozes em atividades acadêmicas desenvolvidas por alunos em formação inicial (2º período, recém‑ingressados na universidade, e por alunos no último ano do Curso (7º período, às vésperas de se formarem. Em vista disso, a análise do corpus contempla as diversas formas pelas quais o sujeito investe-se para dizer o que diz e como diz, com o objetivo de apreender as imagens que ele constrói sobre a própria formação, bem como os papéis sociais que assume e suas ações na esfera acadêmica.Palavras-chave: Posicionamentos identitários. Jogo de vozes. Referência pessoal. Modalizações.

  12. Thermosalinograph data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT219-227 during 2010 (NCEI Accession 0087988)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  13. Depaule Jean-Charles (avec la collaboration de Jean-Luc Arnaud, À travers le mur, Marseille, éditions Parenthèses, collection Eupalinos, 2014, 219 p.

    Directory of Open Access Journals (Sweden)

    Anna Madoeuf

    2014-09-01

    Full Text Available Saluons la réédition, aux éditions Parenthèses, dans la collection Eupalinos, d’À travers le mur, de Jean-Charles Depaule, ouvrage qui est tant une contribution rare et originale aux études urbaines, qu’un opus d’anthropologie sur l’espace habité, de même qu’une source de références multiples, notamment littéraires. « Rêver des lourdes portes, des passages en chicane et plus encore, peut-être des moucharabiehs perdus […] ». Cette sollicitation onirique et énigmatique, quatrième de couverture ...

  14. Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

    Science.gov (United States)

    2012-01-01

    in- tractable pain in advanced rheumatoid arthritis ,” Clinical & Experimental Obstetrics & Gynecology, vol. 29, no. 3, pp. 197– 206, 2002. [118] B. C...Katz, “Neuropathic pain in patients with upper-extremity nerve injury,” Physiotherapy Canada, vol. 62, no. 3, pp. 190–201, 2010. Pain Research and

  15. Hyperspectral surface materials map of quadrangles 3666 and 3766, Balkh (219), Mazar-e Sharif (220), Qarqin (213), and Hazara Toghai (214) quadrangles, Afghanistan, showing iron-bearing minerals and other materials

    Science.gov (United States)

    King, Trude V.V.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected iron-bearing minerals and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. This map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Goethite and jarosite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  16. Hyperspectral surface materials map of quadrangles 3666 and 3766, Balkh (219), Mazar-e Sharif (220), Qarqin (213), and Hazara Toghai (214) quadrangles, Afghanistan, showing carbonates, phyllosilicates, sulfates, altered minerals, and other materials

    Science.gov (United States)

    Kokaly, Raymond F.; King, Trude V.V.; Hoefen, Todd M.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected carbonates, phyllosilicates, sulfates, altered minerals, and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. The map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Epidote or chlorite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  17. 19q13.11 microdeletion concomitant with ins(2;19)(p25.3;q13.1q13.4)dn in a boy: potential role of UBA2 in the associated phenotype.

    Science.gov (United States)

    Venegas-Vega, Carlos; Nieto-Martínez, Karem; Martínez-Herrera, Alejandro; Gómez-Laguna, Laura; Berumen, Jaime; Cervantes, Alicia; Kofman, Susana; Fernández-Ramírez, Fernando

    2014-01-01

    The 19q13.11 microdeletion syndrome (MIM613026) is a clinically recognisable condition in which a 324-kb minimal overlapping critical region has been recently described. However, genes not included within this region, such as WTIP and UBA2, have been proposed to contribute to the clinical characteristics observed in patients. Using cytogenetic techniques, single nucleotide polymorphism arrays, and the quantitative polymerase chain reaction, we identified a novel case with a 2.49-Mb deletion derived from a de novo chromosomal rearrangement. Based on a review of the literature, we support the notion that UBA2 haploinsufficiency could contribute to the phenotype of this rare genomic disorder. UBA2 belongs to a protein complex with sumoylation activity, and several transcription factors, hormone receptors, and signalling proteins related to brain and sexual development are regulated by this post-translational modification. Additional clinical reports and further research on UBA2 molecular function are warranted.

  18. New production in the South China Sea

    Institute of Scientific and Technical Information of China (English)

    CAI; Pinghe

    2002-01-01

    [1]Dugdale, R. C., Goering, J. J., Uptake of new and regenerated nitrogen in primary productivity, Limnology and Oceanog-raphy, 1967, 12: 196-206.[2]Eppley, R. W., Peterson, B. J., Particulate organic matter flux and planktonic new production in the deep ocean, Nature, 1979, 282: 677-680.[3]Allen, C. B., Kanda, J., Laws, E. A., New production and photosynthetic rates within and outside a cyclonic mesoscale eddy in the North Pacific Subtropical gyre, Deep-Sea Research Ⅱ, 1996, 43(6): 917-936.[4]Jenkins, W. J., Tritium-helium dating in the Sargasso Sea: A measurement of oxygen utilization rates, Nature, 1977, 196: 291-292.[5]Spitzer, W. S., Jenkins, W. J., Rates of vertical mixing, gas exchange and new production: Estimates from seasonal gas cy-cle in the upper ocean near Bermuda, Journal of Marine Research, 1989, 47: 169-196.[6]Sarmiento, J. L., Thiele, G., Key, R. M. et al., Oxygen and nitrate new production and remineralization in the North At-lantic Subtropical Gyre, Journal of Geophysical Research, 1990, 95: 18303-18315.[7]Ku, T. L., Luo, S., Kusakabe, M. et al., 228Ra-derived nutrient budgets in upper equatorial Pacific and the role of "new" silicate in limiting productivity, Deep-Sea Research II, 1995, 42(2/3): 479-497.[8]Wheeler, P. A., Rates of nitrate assimilation at the equator during the US-JGOFS spring time series: Estimates of new pro-duction, EOS, Transactions, American Geophysical Union, 1992, 73: 281.[9]Huang, Y., Xie, Y., Chen, M. et al., Distribution feature of 228Ra in surface seawater of the Nansha sea area, in Isotopes Marine Chemistry of Nansha Islands Waters (in Chinese), Beijing: Ocean Press, 1996, 70-78.[10]Reid, D. F., Key, R. M., Schink, D., Radium, thorium and actinium extraction from seawater using an improved manga-nese-oxide-coated fiber, Earth and Planetary Science Letters, 1979, 43: 223-226.[11]Shi, W., Qiu, X., Huang, Y., Distribution of dissolved 226Ra in the Jiulongjiang-Xiamen bay

  19. Study of the origin of elements of the uranium-235 family observed in excess in the vicinity of the experimental nuclear EL4 reactor under dismantling. Lessons got at this day and conclusions; Etude de l'origine des elements de la famille de l'uranium-235 observes en exces dans les environs du reacteur nucleaire experimental EL4 en cours de demantelement. Enseignements retires a ce jour et conclusion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This study resumes the discovery of an excess of actinium 227 found around by EL4 nuclear reactor actually in dismantling. The search for the origin of this excess revealed a real inquiry of investigation during three years. Because a nuclear reactor existed in this area a particular attention will have concerned this region. The doubt became the line of conduct to find the answer to the human or natural origin of this excess. Finally and against any evidence, it appears that the origin of this phenomenon was natural, consequence of the particular local geology. The detail of the different investigations is given: search of a possible correlation with the composition of elevations constituent of lanes, search (and underlining) of new sites in the surroundings of the Rusquec pond and the Plouenez station, study of the atmospheric deposits under winds of the nuclear power plant and in the east direction, search of a possible relationship with the gaseous effluents of the nuclear power plant in the past, historical study of radioactive effluents releases in the fifty last years by the analysis of the sedimentary deposits in the Saint-Herbiot reservoir, search of a possible correlation between the excess of actinium 227 and the nuclear power plant activity; search of a possible correlation with a human activity without any relationship with the nuclear activities, search of a correlation with the underground waters, search of a correlation with the geological context, collect of information on the possible transfers in direction of the food chain, determination of the radiological composition of the underground waters ( not perturbed by human activity), search of the cause of an excess of actinium 227 in the old channel of liquid effluents release of the nuclear power plant. The results are given and discussed. And contrary to all expectations the origin of the excess of actinium 227 is completely natural. (N.C.)

  20. Behaviour of uranium series radionuclides in surface water (Crouzille, Limousin). Geochemical implications; Comportement des radionucleides des familles de l'uranium dans les eaux superficielles du site de la Crouzille (Limousin): implications geochimiques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-06-15

    Understanding natural radionuclides behaviour in surface water is a required step to achieve uranium mine rehabilitation and preserve water quality. The first objective of this thesis is to determine which are the radionuclides sources in a drinking water reservoir. The second objective is to improve the knowledge about the behaviour of uranium series radionuclides, especially actinium. The investigated site is a brook (Sagnes, Limousin, France) which floods a peat bog contaminated by a former uranium mine and which empties into the Crouzille lake. It allows studying radionuclides transport in surface water and radionuclides retention through organic substance or water reservoir. Radionuclides distribution in particulate, colloidal and dissolved phases is determined thanks to ultra-filtrations. Gamma spectrometry allows measuring almost all natural radionuclides with only two counting stages. However, low activities of {sup 235}U series radionuclides impose the use of very low background well-type Ge detectors, such as those of the Underground Laboratory of Modane (France). Firstly, this study shows that no or few radionuclides are released by the Sagnes peat bog, although its radioactivity is important. Secondly, it provides details on the behaviour of uranium series radionuclides in surface water. More specifically, it provides the first indications of actinium solubility in surface water. Actinium's behaviour is very close to uranium's even if it is a little less soluble. (author)

  1. Grids of Agricultural Pesticide Use in the Conterminous United States, 1997

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This spatial dataset consists of 219 1-kilometer (km) resolution grids depicting estimated agricultural use of 219 pesticides in 1997 for the conterminous United...

  2. 77 FR 50631 - Homeland Security Acquisition Regulation (HSAR); Revision Initiative [HSAR Case 2009-002

    Science.gov (United States)

    2012-08-22

    ... Guarantee. (USCG) ----3052.219-70 Small Business Subcontracting Plan Reporting. ----3052.219-71 DHS Mentor.... ----3052.247-70 F.o.B. Origin Information. ----Alternate I ----Alternate II ----3052.247-71 F.o.B....

  3. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    P. Bernot

    2005-07-13

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this activity is to predict dissolved concentrations or solubility limits for elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) relevant to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are provided in the form of tabulated functions with pH and log fCO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. Even though selection of an appropriate set of radionuclides documented in Radionuclide Screening (BSC 2002 [DIRS 160059]) includes actinium, transport of Ac is not modeled in the total system performance assessment for the license application (TSPA-LA) model because of its extremely short half-life. Actinium dose is calculated in the TSPA-LA by assuming secular equilibrium with {sup 231}Pa (Section 6.10); therefore, Ac is not analyzed in this report. The output data from this report are fundamental inputs for TSPA-LA used to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for the actinides discussed in this report. These models cover broad ranges of environmental conditions so they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or

  4. Transition wavelengths and unresolved transition array statistics of ions with Z = 72-89

    Energy Technology Data Exchange (ETDEWEB)

    Kilbane, D, E-mail: Deirdre.Kilbane@ucd.ie [School of Physics, University College Dublin, Belfield, Dublin 4 (Ireland)

    2011-08-28

    Potential extreme ultraviolet and soft x-ray radiation sources have been identified, using the flexible atomic code (FAC), as emission peaks arising from the 4d-4f and 4p-4d transitions in Pd-like to Rb-like ions of hafnium through actinium. The effects of configuration interaction are investigated and for increasing nuclear charge, these strong emitters are seen to separate and move to shorter wavelengths. Each source is characterized using the unresolved transition array model. They are proposed to complement the currently used nitrogen and argon sources in the 'water window', and as possible successors to tin in next-generation lithography.

  5. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  6. Analysis of the Yrast Bands with q-Deformed Moment of Inertia

    Institute of Scientific and Technical Information of China (English)

    FANG Xiang-Zheng; RUAN Tu-Nan

    2001-01-01

    The rigid-rotor with a q-deformed moment of inertia is introduced to describe the nuclear rotational spectra. With the representations of quantum algebra, the normal deformed and superdeformed bands are naturally differentiated by softness. The yrast normal deformed bands in rare earth and actinium regions, as well as the yrast superdeformed bands in A-190 and 150 regions are investigated. The calculated results agree with experimental data qualitatively well, and the values of the parameters are physically reasonable. This indicates that the fixed deformation, the stretching effect and the many body statistics effect are three possible dominant factors to govern nuclear rotational bands.

  7. 48 CFR 1819.7302 - NASA contract clauses.

    Science.gov (United States)

    2010-10-01

    ... to Public Law 97-219 (the Small Business Innovation Development Act of 1982). (b) Contracting... pursuant to Public Law 97-219 (the Small Business Innovation Development Act of 1982). (c) Contracting... Law 97-219 (the Small Business Innovation Development Act of 1982). (d) Contracting officers...

  8. Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France.

    Science.gov (United States)

    Mancini, F R; Paul, D; Gauvreau, J; Volatier, J L; Vin, K; Hulin, M

    2015-01-01

    This study aimed to estimate the exposure to seven additives (benzoates, parabens, nitrites, nitrates, BHA, BHT and aspartame) in children aged less than 3 years old in France. A conservative approach, combining individual consumption data with maximum permitted levels, was carried out for all the additives. More refined estimates using occurrence data obtained from products' labels (collected by the French Observatory of Food Quality) were conducted for those additives that exceeded the acceptable daily intake (ADI). Information on additives' occurrence was obtained from the food labels. When the ADI was still exceeded, the exposure estimate was further refined using measured concentration data, if available. When using the maximum permitted level (MPL), the ADI was exceeded for benzoates (1.94 mg kg(-1) bw day(-1)), nitrites (0.09 mg kg(-1) bw day(-1)) and BHA (0.39 mg kg(-1) bw day(-1)) in 25%, 54% and 20% of the entire study population respectively. The main food contributors identified with this approach were current foods as these additives are not authorised in specific infant food: vegetable soups and broths for both benzoates and BHA, delicatessen and meat for nitrites. The exposure estimate was significantly reduced when using occurrence data, but in the upper-bound scenario the ADI was still exceeded significantly by the age group 13-36 months for benzoates (2%) and BHA (1%), and by the age group 7-12 months (16%) and 13-36 months (58%) for nitrites. Measured concentration data were available exclusively for nitrites and the results obtained using these data showed that the nitrites' intake was below the ADI for all the population considered in this study. These results suggest that refinement of exposure, based on the assessment of food levels, is needed to estimate the exposure of children to BHA and benzoates for which the risk of exceeding the ADI cannot be excluded when using occurrence data.

  9. RESEÑA DE: CASTRO, Demetrio (coord.: Líderes para el pueblo republicano: liderazgo político en el republicanismo español del siglo XIX. Pamplona, UPNA, 2015, 219 pp. ISBN: 978-8-9769-296-0.

    Directory of Open Access Journals (Sweden)

    Magda Berges Giral

    2016-05-01

    Full Text Available La obra que nos ocupa difunde un proyecto de investigación iniciado en el 2008 bajo el título «Estilos de liderazgo político. Un estudio de caso: el republicanismo español en la segunda mitad del siglo XIX» dirigido por Demetrio Castro. El resultado ha sido una obra colectiva entre seis autores, la mayoría especializados en historia del pensamiento político contemporáneo. Seis investigaciones donde el tema central es el proceso de liderazgo. Se trata, por tanto, de una incursión en el concepto de liderazgo a modo de continuación de lo que fueron los análisis políticos en las ciencias sociales del ámbito anglosajón, aprovechando el auge del género biográfico y desde la perspectiva de la historia política. 

  10. R&D of φ1 219 mm X80 LSAW linepipe for No.2 west-east gas transmission pipeline projec%西气东输二线管道工程用X80钢级φ1219 mm直缝埋弧焊管的研发

    Institute of Scientific and Technical Information of China (English)

    李延丰

    2009-01-01

    介绍了西气东输二线管道工程用X80钢级φ1219 mm直缝埋弧焊管的研发情况.主要分析研究了X80钢级φ1219 mm直缝埋弧焊管的JCO成型、焊接、机械扩径、超声波自动探伤等技术;X80钢的理化性能试验结果;X80钢制管前后的拉伸性能、夏比冲击韧性、DWTT性能变化;X80钢级钢板夏比冲击韧性与温度的关系、屈强比的合理确定.

  11. Erratum: The article „Morphometric analysis of collagen and inflammatory cells in periodontal disease” [Morfometrijska analiza kolagena i inflamatornih ćelija u periodontalnoj bolesti]. Vojnosanit pregl 2015; 72(3: 219-224. (DOI:10.2298/VSP130627076G

    Directory of Open Access Journals (Sweden)

    Editorial

    2017-01-01

    Full Text Available The authors and their affiliations were listed as follows: Ranko Golijanin*†, Bojan Kujundžić†, Zoran Milosavljević‡, Dragan R. Milovanovi槆†, Zlatibor Andjelković║, Miroslav Obrenović¶, Radivoje Nikolić**†† *Department of Dentistry, ‡Department of Histology and Embriology, §Department of Pharmacology and Toxicology, **Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; †Faculty of Dental Medicine, ¶Faculty of Medicine, University of East Sarajevo, Foča, Republic of Srpska, Bosnia and Herzegovina; ††Clinical Center “Kragujevac”, Kragujevac, Serbia Listed the authors and their affiliations should read as: Ranko Golijanin*†, Bojan Kujundžić†, Zoran Milosavljević‡, Dragan R. Milovanovi槆†, Zlatibor Andjelković║, Miroslav Obrenović¶, Radivoje Nikolić**†† *Department of Dentistry, ‡Department of Histology and Embriology, §Department of Pharmacology and Toxicology, **Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; ║Department of Histology, Faculty of Medicine, University of Priština, Kosovska Mitrovica, Serbia; †Faculty of Dental Medicine, ¶Faculty of Medicine, University of East Sarajevo, Foča, Republic of Srpska, Bosnia and Herzegovina; ††Clinical Center “Kragujevac”, Kragujevac, Serbia Link to the corrected article 10.2298/VSP130627076G

  12. Development of Φ1219mm×22mm LSAW Pipe in Mo-containing X80 Steel Grade%Φ1 219mm×22mm X80钢级含Mo直缝埋弧焊管的开发

    Institute of Scientific and Technical Information of China (English)

    李延丰; 任毅; 陈小伟

    2008-01-01

    通过研制西气东输二线天然气管道工程用Φ1219mm×22mm X80钢级含Mo直缝埋弧焊管,研究了X80钢级含Mo钢板的焊接性、热影响区的弱化,并对矩形和圆棒拉伸试样进行了对比试验分析,对Φ1219mm×22mm X80钢级HTP与含Mo直缝埋弧焊管的主要性能进行了对比分析.提出了厚壁X80钢级管线钢管的拉伸试验应采用圆棒试样的建议.

  13. Dicty_cDB: [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VF (Link to library) VFC219 (Link to dictyBase) - - - Contig-U16590-1 VFC219P (Link... to Original site) VFC219F 361 VFC219Z 604 VFC219P 965 - - Show VFC219 Library VF (Link to library) Clone ID VFC219 (Link to di...ctyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16590-1 Original site URL http://di...MTGKPTRT**ncqkexti Frame C: cwptgkyfffdlklic*killikriylliinktxfk*lkeik*qivqliikdi...0 mNt: 0.00 m3a: 0.00 m3b: 0.00 m_ : 1.00 40.0 %: cytoplasmic 32.0 %: nuclear 16.0 %: mitochondrial 12.0 %: cytoskeletal >> predi

  14. Purification of cerium, neodymium and gadolinium for low background experiments

    Directory of Open Access Journals (Sweden)

    Boiko R.S.

    2014-01-01

    Full Text Available Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search, 136Ce (2β+ candidate with one of the highest Q2β. The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  15. Large scale accelerator production of (225)Ac: Effective cross sections for 78-192MeV protons incident on (232)Th targets.

    Science.gov (United States)

    Griswold, J R; Medvedev, D G; Engle, J W; Copping, R; Fitzsimmons, J M; Radchenko, V; Cooley, J C; Fassbender, M E; Denton, D L; Murphy, K E; Owens, A C; Birnbaum, E R; John, K D; Nortier, F M; Stracener, D W; Heilbronn, L H; Mausner, L F; Mirzadeh, S

    2016-12-01

    Actinium-225 and (213)Bi have been used successfully in targeted alpha therapy (TAT) in preclinical and clinical research. This paper is a continuation of research activities aiming to expand the availability of (225)Ac. The high-energy proton spallation reaction on natural thorium metal targets has been utilized to produce millicurie quantities of (225)Ac. The results of sixteen irradiation experiments of thorium metal at beam energies between 78 and 192MeV are summarized in this work. Irradiations have been conducted at Brookhaven National Laboratory (BNL) and Los Alamos National Laboratory (LANL), while target dissolution and processing was carried out at Oak Ridge National Laboratory (ORNL). Excitation functions for actinium and thorium isotopes, as well as for some of the fission products, are presented. The cross sections for production of (225)Ac range from 3.6 to 16.7mb in the incident proton energy range of 78-192MeV. Based on these data, production of curie quantities of (225)Ac is possible by irradiating a 5.0gcm(-2 232)Th target for 10 days in either BNL or LANL proton irradiation facilities. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. The Technological Enhancement of Normally Occurring Radioactive Materials in Red Mud due to the Production of Alumina

    Directory of Open Access Journals (Sweden)

    Maurice O. Miller

    2016-01-01

    Full Text Available This study investigates the level of technological enhancement of normally occurring radioactive materials (TENORM in the red mud waste due to the production of alumina in Jamaica. Technological enhancements factors (TEF were determined for the uranium, thorium, actinium series, their progenies, and the nonseries potassium-40 using gamma spectrometry. The study concluded that bauxite production technologically enhances the uranium progenies Th-234, Pb-214, Bi-214, and Pa-234 and the thorium-232 progenies Ac-228, Pb-212, and Bi-212 in red mud. The actinium series was technologically enhanced, but K-40 and the thorium daughter, Tl-208, were reduced. The spectrometric comparison of Tl-208 (at 510 keV was unexpected since its other photopeaks at 583 keV, 934 keV, and 968 keV were markedly different. An explanation for this anomaly is discussed. An explanation regarding the process of accumulation and fractionation of organically derived phosphate deposits and potassium-feldspar is offered to explain the spectrometric differences between the alumina product and its waste material, red mud.

  17. 76 FR 55933 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2011-09-09

    ... Agency: Air Force Property Number: 18201130005 Status: Unutilized Directions: 219, 250, 1409, 1410, 1902... Newington NH 03803 Landholding Agency: Air Force Property Number: 18201130031 Status: Excess Reasons:...

  18. EST Table: FS871503 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS871503 E_FL_fner_45K10_R_0 10/09/28 90 %/219 aa ref|NP_001036841.1| Annexin IX is...oform A [Bombyx mori] dbj|BAA92809.1| annexin IX-A [Bombyx mori] 10/09/11 73 %/219 aa FBpp0280989|DpseGA1909...1|gene:ANXB9 10/09/10 61 %/219 aa gnl|Amel|GB16448-PA 10/09/10 73 %/219 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] FS780436 fner ...

  19. Modélisation pluie-débit en région tropicale humide : application des réseaux de neurones sur quatre stations hydrométriques du Bandama Blanc (Bada, Marabadiassa, Tortiya et Bou situées au Nord de la Côte d'Ivoire. Thèse de l'Université de Cocody (Côte d'Ivoire, 2007, 219 p.

    Directory of Open Access Journals (Sweden)

    Yao Blaise Koffi

    2009-12-01

    Full Text Available La relation pluie-débit fait l'objet de nombreuses études, à cause de son importance dans la mise en œuvre de nombreux projets de développement. La communauté scientifique, dans le souci de faire face aux problèmes d'eau, tels que les inondations et les sècheresses, utilise différents modèles. Mais ces modèles sont généralement confrontés à la non-linéarité de la relation pluie-débit. Dans le cas du Bandama Blanc, objet de cette étude, cette non-linéarité est accentuée par la présence de plusieurs barrages à vocation agro-pastorale situés dans la partie nord de la zone d'étude et qui utilisent les eaux de ce fleuve. Ce mémoire de thèse traite donc de la modélisation des débits mensuels du Bandama Blanc, aux stations de Bada, Marabadiassa, Tortiya et Bou, à l'aide des réseaux de neurones, déjà éprouvés dans ce contexte de relation non-linéaire. Elle projette de fournir des outils plus robustes aux hydrologues africains pour la simulation et la prévision des débits des rivières jaugées. Pour atteindre cet objectif, deux Perceptrons Multicouches entraînés avec l'algorithme de la rétropropagation de l'erreur ont été construits. Le premier modèle a été utilisé seulement en simulation et le second en simulation et en prévision. Le modèle conceptuel GR2M, a été utilisé pour valider les résultats obtenus avec les réseaux de neurones. Pour cette étude, une importante base de données climatiques (pluie et température et hydrométriques (débits mensuels a été utilisée. Les résultats obtenus sont forts satisfaisants et nettement supérieurs à ceux obtenus avec le modèle conceptuel global GR2M. En effet, les réseaux de neurones parviennent à expliquer plus de 70 % de la variation des débits, avec des coefficients de corrélation de Pearson qui excèdent 0,80. Cependant ces modèles arrivent difficilement à simuler et à faire la prévision des débits extrêmes (étiages et crues, à cause probablement du nombre réduit de données à notre disposition et de la séparation des bases de calage et de validation.The rainfall-runoff relationship is the subject of many studies because of its importance in the implementation of many development projects. The scientific community, in order to cope with water problems such as floods and droughts, used different models. But these models are usually faced with the non-linearity of the rainfall-runoff relationship. In the case of the Bandama Blanc purpose of this study, this non-linearity is enhanced by the presence of several agro-pastoral dams located in the northern part of the study area and using the waters of this river. This thesis therefore deals with the modeling of flows of Bandama Blanc hydrometric stations (Bada Marabadiassa, Tortiya and Bou using neural networks already experienced in the context of non-linear relationship. It plans to provide more robust tools to African hydrologist in the simulation and forecasting of river flows. To achieve this goal, two Multilayer Perceptrons trained with the backpropagation algorithm of error have been built. The first model was used only in simulation and the second in simulation and prediction. The conceptual model GR2M was used to validate the results obtained with neural networks. An extensive database climate (rainfall and temperature and river monthly flow was used in this study. The results obtained are very satisfactory and well above those obtained with the overall conceptual model GR2M. Indeed, neural networks are able to explain more than 70% of the variation in rates, with Pearson correlation coefficients exceeding 0.80. However, these models have difficulty to simulate and predict extremes flow probably because of the reduced number of data at our disposal and separation of bases calibration and validation.

  20. Comparecencia del señor director de la Cátedra de Accessibilidad, Arquitectura, Diseño y Tecnología para todos de la Universitat Politècnica de Catalunya, UPC (Guasch Murillo), para informar sobre temas relacionados con el objeto de la misma. A petición del grupo parlamentario catalán (Convergència i Unió). (Número de expediente 219/000320.)

    OpenAIRE

    Guasch Murillo, Daniel

    2010-01-01

    Transcripció de la intervenció en la comparescència del director de la Càtedra d'Accessibilitat, Arquitectura, Disseny i Tecnologia de la Universitat Politècnica, Daniel Guasch Murillo a la Comisión para las políticas integrales de la discapacidad al Congrès dels Diputats

  1. Process for radioisotope recovery and system for implementing same

    Science.gov (United States)

    Meikrantz, David H.; Todd, Terry A.; Tranter, Troy J.; Horwitz, E. Philip

    2007-01-02

    A method of recovering daughter isotopes from a radioisotope mixture. The method comprises providing a radioisotope mixture solution comprising at least one parent isotope. The at least one parent isotope is extracted into an organic phase, which comprises an extractant and a solvent. The organic phase is substantially continuously contacted with an aqueous phase to extract at least one daughter isotope into the aqueous phase. The aqueous phase is separated from the organic phase, such as by using an annular centrifugal contactor. The at least one daughter isotope is purified from the aqueous phase, such as by ion exchange chromatography or extraction chromatography. The at least one daughter isotope may include actinium-225, radium-225, bismuth-213, or mixtures thereof. A liquid-liquid extraction system for recovering at least one daughter isotope from a source material is also disclosed.

  2. Temporal Variations in Surface Concentrations of Terrestrial Lead 210 and Uranium 235 Radionucleides

    Science.gov (United States)

    Yoshimori, M.

    We have started to measure the surface concentrations of terrestrial radionucleides of lead 210 and uranium 235 in Tokyo (N35, E139) in 2002. Lead 210 which is a daughter nucleus of Rn-222 (uranium series) emits 46 keV gamma-ray with a half-life of 22.4 years, while uranium 235 (actinium series) emits a gamma-ray at 186 keV with a half-life of 0.7 billion years. The present measurement of the surface concentration of lead 210 exhibits two peaks in spring and fall, similar to the beryllium 7 seasonal variations, while the uranium 235 concentration does not vary with time within statistical errors. These two terrestrial radionucleides exhibit different temporal variations on the surface. We discuss possible explanations for the differences in the temporal variations from a point of view of differences in their altitude distribution.

  3. Towards high-resolution laser ionization spectroscopy of the heaviest elements in supersonic gas jet expansion

    Science.gov (United States)

    Ferrer, R.; Barzakh, A.; Bastin, B.; Beerwerth, R.; Block, M.; Creemers, P.; Grawe, H.; de Groote, R.; Delahaye, P.; Fléchard, X.; Franchoo, S.; Fritzsche, S.; Gaffney, L. P.; Ghys, L.; Gins, W.; Granados, C.; Heinke, R.; Hijazi, L.; Huyse, M.; Kron, T.; Kudryavtsev, Yu.; Laatiaoui, M.; Lecesne, N.; Loiselet, M.; Lutton, F.; Moore, I. D.; Martínez, Y.; Mogilevskiy, E.; Naubereit, P.; Piot, J.; Raeder, S.; Rothe, S.; Savajols, H.; Sels, S.; Sonnenschein, V.; Thomas, J-C; Traykov, E.; Van Beveren, C.; Van den Bergh, P.; Van Duppen, P.; Wendt, K.; Zadvornaya, A.

    2017-01-01

    Resonant laser ionization and spectroscopy are widely used techniques at radioactive ion beam facilities to produce pure beams of exotic nuclei and measure the shape, size, spin and electromagnetic multipole moments of these nuclei. However, in such measurements it is difficult to combine a high efficiency with a high spectral resolution. Here we demonstrate the on-line application of atomic laser ionization spectroscopy in a supersonic gas jet, a technique suited for high-precision studies of the ground- and isomeric-state properties of nuclei located at the extremes of stability. The technique is characterized in a measurement on actinium isotopes around the N=126 neutron shell closure. A significant improvement in the spectral resolution by more than one order of magnitude is achieved in these experiments without loss in efficiency. PMID:28224987

  4. Origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department); Origine des elements de la famille de l'uranium-235 observes dans la riviere Ellez a proximite du reacteur nucleaire experimental EL4 en cours de demantelement (Mont d'Arree - departement du Finistere). Resultats et premiers constats annee 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 ({sup 227}Ac), non born by its ascendents which are {sup 235}U and {sup 231}Pa is observed. This phenomenon is characterized by mass activities superior to these ones of {sup 235}U and able to reach these ones of {sup 238}U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil ({sup 210}Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  5. Evaluation of total effective dose due to certain environmentally placed naturally occurring radioactive materials using a procedural adaptation of RESRAD code.

    Science.gov (United States)

    Beauvais, Z S; Thompson, K H; Kearfott, K J

    2009-07-01

    Due to a recent upward trend in the price of uranium and subsequent increased interest in uranium mining, accurate modeling of baseline dose from environmental sources of radioactivity is of increasing interest. Residual radioactivity model and code (RESRAD) is a program used to model environmental movement and calculate the dose due to the inhalation, ingestion, and exposure to radioactive materials following a placement. This paper presents a novel use of RESRAD for the calculation of dose from non-enhanced, or ancient, naturally occurring radioactive material (NORM). In order to use RESRAD to calculate the total effective dose (TED) due to ancient NORM, a procedural adaptation was developed to negate the effects of time progressive distribution of radioactive materials. A dose due to United States' average concentrations of uranium, actinium, and thorium series radionuclides was then calculated. For adults exposed in a residential setting and assumed to eat significant amounts of food grown in NORM concentrated areas, the annual dose due to national average NORM concentrations was 0.935 mSv y(-1). A set of environmental dose factors were calculated for simple estimation of dose from uranium, thorium, and actinium series radionuclides for various age groups and exposure scenarios as a function of elemental uranium and thorium activity concentrations in groundwater and soil. The values of these factors for uranium were lowest for an adult exposed in an industrial setting: 0.00476 microSv kg Bq(-1) y(-1) for soil and 0.00596 microSv m(3) Bq(-1) y(-1) for water (assuming a 1:1 234U:238U activity ratio in water). The uranium factors were highest for infants exposed in a residential setting and assumed to ingest food grown onsite: 34.8 microSv kg Bq(-1) y(-1) in soil and 13.0 microSv m(3) Bq(-1) y(-1) in water.

  6. 两种稀土产品中放射性核素分析研究%ANALYSIS OF RADIONUCLIDES IN TWO RARE EARTH PRODUCTS

    Institute of Scientific and Technical Information of China (English)

    周程; 孙恋君

    2009-01-01

    利用高纯锗γ谱仪对两个稀土产品氯化镧和氯化钇的样品进行能谱分析,研究经湿法冶炼工艺后的稀土产品中放射性核素的活度变化.结果表明,样品中存在天然放射性钍系和锕-铀系的核素,以及天然放射性核素~(138)La和~(176)Lu,但两个样品中所含的放射性核素不相同.氯化镧产品中锕-铀系和钍系核素放射性未达平衡,其主要子体~(224)Ra和~(227)Th的含量随时间发生明显变化,约60天达到平衡;而氯化钇产品没有这种现象.%This paper describes a study on raidoactivity change of rare-earth products after hydrometallurgy technology,using HPGe gamma spectrometer to analyze two rare earth products (LaCl_3 and YCl_3).The results show that in the two samples exist natural radionuclides of thorium series and actinium-uranium series as well as other natural radionuclides 138 La and 176 Lu.In the sample of lanthanum chloride the radioactivity of actinium-uranium series and thorium series has not reached balance,the contents of their main progenies ~(226)Ra and ~(227)Th obviously changes with the time,reaching balance 60 days later,while YCl_3 keeps stability.

  7. Reference: 516 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available in219 mutant under all light conditions, except cFR. Furthermore, promoter activi...velopmentally regulated. Subcellular localization studies revealed that the beta-glucuronidase-FIP1 fusion p...icate that FIP1 may interact with FIN219 to regulate cell elongation and flowering in response to light. Glu

  8. 10kW TWT Transition to GaN IRE

    Science.gov (United States)

    2015-03-31

    Office. Phase III of this effort would align to a NISE 219 project due to the amount of funding required for thermal modeling and analysis, FEA...done to prepare the 10kW TWT transition to GaN for sponsorship by a Program Office. Phase III of this effort would align to a NISE 219 project due to

  9. 77 FR 76936 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

    Science.gov (United States)

    2012-12-31

    ..., Contractor Code of Business Ethics and Conduct, is the DoD Office of Inspector General at the following...'' and adding ``datafax (571) 372-6094'' in its place. PART 203--IMPROPER BUSINESS PRACTICES AND PERSONAL.../ CPF'' and adding ``DPAP/CPIC'' in its place. PART 219--SMALL BUSINESS PROGRAMS 219.202-1 0 8. Section...

  10. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 13. Source Selection and Information Use by U.S. Aerospace Engineers and Scientists: Results of a Telephone Survey

    Science.gov (United States)

    1992-09-01

    Aerospace Knowledge Diffusion Research Project. Government Information Quarterly 8(2), 219- 233. Shuchman, H. L. (1981). Information Transfer in...Research Project. Reprinted from Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas

  11. Engineering Work and Information Use in Aerospace: Results of a Telephone Survey

    Science.gov (United States)

    1992-10-01

    and Rebecca 0. Barclay. "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8.2 (1991): 219-233. Polanyi...Aerospace Knowledge Diffusion Research Project. Reprinteo .om Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA

  12. NASA/DOD Aerospace Knowledge Diffusion Research Project. A Comparison of the Technical Communication Practices of Aerospace Engineers and Scientists in India and the United States

    Science.gov (United States)

    1993-09-01

    34The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2 (1991): 219-233. 35 APPENDIX A AEROSPACE KNOWLEDGE... Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas E. and John M. Kennedy. The

  13. Technical Uncertainty and Project Complexity as Correlates of Information Use by U.S. Industry-Affiliated Aerospace Engineers and Scientists: Results of an Exploratory Investigation

    Science.gov (United States)

    1993-09-01

    Barclay. (1991). "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2, 219-233. Randolph, W. Alan. (1978...from Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas E. and John M. Kennedy

  14. 77 FR 44144 - National Forest System Land Management Planning; Correction

    Science.gov (United States)

    2012-07-27

    ... Forest Service 36 CFR Part 219 RIN 0596-AD02 National Forest System Land Management Planning; Correction...) published a National Forest System land management planning rule in the Federal Register, on April 9, 2012..., Subpart A--National Forest System Land Management Planning (36 CFR part 219, subpart A). One technical...

  15. One Year Oral Toxicity Study of WR238605 Succinate in Dogs. Volume 2

    Science.gov (United States)

    1997-07-18

    219 SEX: MALE Animal ID RBC HGB 10*6/IJITIA3 g/dL HCT HCV MCH MCHC % fL...PRTL219 Urinalvsis Qualitative Bilirubin Nitrite Glucose pH Ketones Protein Occult Blood Urobilinogen Leukocytes Color Specific Gravity

  16. 77 FR 54923 - Minor Boundary Revision at Big Thicket National Preserve

    Science.gov (United States)

    2012-09-06

    ... National Park Service Minor Boundary Revision at Big Thicket National Preserve AGENCY: National Park..., pursuant to the Act of October 11, 1974 (Pub. L. 93- 439, 88 Stat. 1245), the boundary of Big Thicket...; Tract 219-12, 6.45 acres; Tract 219- 13, 177.28 acres; Tract 221-15, 8.51 acres; Tract 221-16,...

  17. 78 FR 51240 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2013-08-20

    ... of Proposed Rule Change To Eliminate Rules Related to CYCLE Routing August 14, 2013. Pursuant to... Change The Exchange filed a proposal to eliminate Rules 11.13(a)(3)(A) and 21.9(a)(2)(A), which are the.... Purpose The Exchange is proposing to eliminate Rules 11.13(a)(3)(A) and 21.9(a)(2)(A), which are...

  18. 78 FR 64929 - National Advisory Committee on Institutional Quality and Integrity (NACIQI)

    Science.gov (United States)

    2013-10-30

    ... December 13, 2013 from 8:00 a.m. to 5:30 p.m., at the Liaison Capitol Hill Hotel, 415 New Jersey Ave. NW... Griffiths, Executive Director, NACIQI, U.S. Department of Education, 1990 K Street NW., Room 8073, Washington, DC 20006-8129, telephone: (202) 219-7035, fax: (202) 219- 7005, or email:...

  19. Dicty_cDB: Contig-U14672-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available , Expect = 4e-19 Identities = 49/49 (100%) Strand = Plus / Plus Query: 171 ccaccaaagtttcanaccttgctatttattttt...aaatatattattctaa 219 ||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 171 ccaccaaagtttcanaccttgctatt...ad. Length = 320 Score = 91.7 bits (46), Expect(3) = 3e-25 Identities = 49/49 (100%) Strand = Plus / Plus Query: 171 ccaccaaagtttcan...||||||||||||||||||||||||||||||| Sbjct: 171 ccaccaaagtttcanaccttgctatttatttttaaatatattattctaa 219 Score = 40.

  20. 75 FR 40019 - In the Matter of the Review of the Designation of the Communist Party of the Philippines/New...

    Science.gov (United States)

    2010-07-13

    ... Matter of the Review of the Designation of the Communist Party of the Philippines/New People's Army (aka... matter pursuant to Section 219(a)(4)(C) of the Immigration and Nationality Act, as amended (8 U.S.C. 1189... organization as a foreign terrorist organization, pursuant to Section 219 of the INA (8 U.S.C. 1189), shall...

  1. 48 CFR 819.709 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 819.709 Contract clause. The contracting officer shall insert VAAR clause 852.219-9, Small Business Subcontracting Plan Minimum Requirements, in solicitations and contracts that include FAR clause 52.219-9, Small Business...

  2. 75 FR 57396 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2010-09-21

    ... 291 ...... ...... Rolls Royce Phantom 2004 455 ...... ...... Saab 9.3 2003 426 ...... ...... Saab 9000 1988 59 ...... ...... Saab 9000 1994 334 ...... ...... Saab 900 S 1987-1989 270 ...... ...... Saab 900 SE 1995 213 ...... ...... Saab 900 SE 1990-1994 219 ...... ...... Saab 900 SE 1996-1997 219...

  3. 78 FR 54182 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2013-09-03

    ... Rolls Royce Phantom 2004 455 Saab 9.3 2003 426 Saab 900 S 1989 270 Saab 900 SE 1995 213 Saab 900 SE 1990-1994 219 Saab 900 SE 1996-1997 219 Saab 9000 1994 334 Smart Car Fortwo coupe & cabriolet (incl. 2005 30...

  4. 77 FR 59829 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2012-10-01

    ... ..... ..... Rolls Royce Phantom........ 2004 455 ..... ..... Saab 9.3 2003 426 ..... ..... Saab 900 S 1988-1989 270 ..... ..... Saab 900 SE......... 1995 213 ..... ..... Saab 900 SE......... 1990-1994 219 ..... ..... Saab 900 SE......... 1996-1997 219 ..... ..... Saab 9000 1988 59 ..... ..... Saab 9000 1994 334 ..... ..... Smart Car Fortwo...

  5. Dicty_cDB: Contig-U06096-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available |||||||||||| Sbjct: 64 gaaatngatgntncaacnccaacaatggctgcaaanattttttnnccnttttcaattggt 123 Query: 124 ggnaatgttggngatgntacaacnccna...ctt 154 ||||||||||||||||||||||||||||||| Sbjct: 124 ggnaatgttggngatgntacaacnccnactt 154 Sc...us Query: 219 atcncaacnatnncaacaacnaactgaatcagaattacnaccnattcaaa 268 |||||||||||||||||||||||||||||||||||||||...||||||||||| Sbjct: 219 atcncaacnatnncaacaacnaactgaatcagaattacnaccnattcaaa 268 >Contig-U11917-1 (Contig-U1191...atgntncaacnccaacaatggctgcaaanattttttnnccnttttcaattggt 147 Query: 124 ggnaatgttggngatgntacaacnccnacttnaaaanaa

  6. 75 FR 13265 - National Board for Education Sciences

    Science.gov (United States)

    2010-03-19

    .... ADDRESSES: 80 F Street, NW., Room 100, Washington, DC 20208. FOR FURTHER INFORMATION CONTACT: Norma Garza..., DC 20208; phone: (202) 219-2195; fax: (202) 219- 1466; e-mail: Norma.Garza@ed.gov . Individuals who...:30 p.m. A final agenda will be available from Norma Garza (see contact information above) on March...

  7. 75 FR 53280 - National Board for Education Sciences

    Science.gov (United States)

    2010-08-31

    ... CONTACT: Norma Garza, Executive Director, National Board for Education Sciences, 555 New Jersey Ave., NW., Room 602K, Washington, DC 20208; phone: (202) 219-2195; fax: (202) 219-1466; e-mail: Norma.Garza@ed.gov... alternative format) should notify Norma Garza no later than September 20. We will attempt to meet requests...

  8. Seabottom backscatter studies in the western continental shelf of India

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B.; Pathak, D.

    stream_size 12 stream_content_type text/plain stream_name J_Sound_Vibrat_219_51.pdf.txt stream_source_info J_Sound_Vibrat_219_51.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  9. Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate.

    Science.gov (United States)

    Chen, Wen-Hsiang; Du, Lanying; Chag, Shivali M; Ma, Cuiqing; Tricoche, Nancy; Tao, Xinrong; Seid, Christopher A; Hudspeth, Elissa M; Lustigman, Sara; Tseng, Chien-Te K; Bottazzi, Maria Elena; Hotez, Peter J; Zhan, Bin; Jiang, Shibo

    2014-01-01

    Development of vaccines for preventing a future pandemic of severe acute respiratory syndrome (SARS) caused by SARS coronavirus (SARS-CoV) and for biodefense preparedness is urgently needed. Our previous studies have shown that a candidate SARS vaccine antigen consisting of the receptor-binding domain (RBD) of SARS-CoV spike protein can induce potent neutralizing antibody responses and protection against SARS-CoV challenge in vaccinated animals. To optimize expression conditions for scale-up production of the RBD vaccine candidate, we hypothesized that this could be potentially achieved by removing glycosylation sites in the RBD protein. In this study, we constructed two RBD protein variants: 1) RBD193-WT (193-aa, residues 318-510) and its deglycosylated forms (RBD193-N1, RBD193-N2, RBD193-N3); 2) RBD219-WT (219-aa, residues 318-536) and its deglycosylated forms (RBD219-N1, RBD219-N2, and RBD219-N3). All constructs were expressed as recombinant proteins in yeast. The purified recombinant proteins of these constructs were compared for their antigenicity, functionality and immunogenicity in mice using alum as the adjuvant. We found that RBD219-N1 exhibited high expression yield, and maintained its antigenicity and functionality. More importantly, RBD219-N1 induced significantly stronger RBD-specific antibody responses and a higher level of neutralizing antibodies in immunized mice than RBD193-WT, RBD193-N1, RBD193-N3, or RBD219-WT. These results suggest that RBD219-N1 could be selected as an optimal SARS vaccine candidate for further development.

  10. Doctoral Theses in Library and Information Science Completed in Indian Universities, 2001-2007

    Science.gov (United States)

    Mestri, D. D.

    2008-01-01

    Provides a complete listing and analysis of 219 doctoral theses submitted to the departments of library and information science (DLIS) in 45 Indian universities between January 2001 and December 2007. (Contains 10 tables.)

  11. 76 FR 44394 - Public Transportation on Indian Reservations Program; Tribal Transit Program

    Science.gov (United States)

    2011-07-25

    ... 20006, Tel. 202-219- Northern Mariana Islands. 3562. Los Angeles Metropolitan Yvette Taylor, Regional Administrator, Office, Region 9-Los Angeles, Region 4-Atlanta, 230 Peachtreet 888 S. Figueroa Street,...

  12. FastStats: Sinus Conditions

    Science.gov (United States)

    ... please visit this page: About CDC.gov . FastStats Homepage Diseases and Conditions Anemia or Iron Deficiency Arthritis ... Statistics Tables for U.S. Adults: National Health Interview Survey, 2014, Table A-2 [PDF - 219 KB] Physician ...

  13. 78 FR 38442 - Notice of Receipt of Petition for Decision That Nonconforming 2005-2006 Mercedes Benz SLR...

    Science.gov (United States)

    2013-06-26

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary..., 216 Roof Crush Resistance, 219 Windshield Zone Intrusion, and 302 Flammability of Interior...

  14. 77 FR 67732 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Porsche Cayenne S Multipurpose...

    Science.gov (United States)

    2012-11-13

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorage Systems, and 302 Flammability...

  15. 77 FR 17567 - Notice of Receipt of Petition for Decision That Nonconforming Right-Hand Drive 2000-2003 Jeep...

    Science.gov (United States)

    2012-03-26

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Resistance, 219 Windshield Zone Intrusion, and 302 Flammability of Interior Materials. The petitioner...

  16. 75 FR 19461 - Receipt of Petition for Decision That Nonconforming 2006 and 2007 Mercedes Benz G-Class Long...

    Science.gov (United States)

    2010-04-14

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the... Resistance, 219 Windshield Zone Intrusion, 301 Fuel System Integrity, and 302 Flammability of...

  17. 47 CFR 80.179 - Unattended operation.

    Science.gov (United States)

    2010-10-01

    ...-band direct-printing (NB-DP) operations in accordance with § 80.219. (c) Automatic use of a transmitter... selectively addressed to an individual station. (5) Transmitter output power must not exceed one watt. (6)...

  18. 78 FR 36621 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2013-06-18

    ... of a Proposed Rule Change To Amend Rule 2.11, Entitled ``BATS Trading, Inc. as Outbound Router'' June... Trading, Inc. as Outbound Router'', and Rule 21.9, entitled ``Order Routing'', with respect to...

  19. Disease: H00561 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available nsufficiency of HDAC4 causes brachydactyly mental retardation syndrome, with brachydactyly type E, developmental delays, and behavior...al problems. Am J Hum Genet 87:219-28 (2010) PMID:7847374 (description, gene) Wilso

  20. Revised Proof of the Uniqueness Theorem for "No Collapse" Interpretations of Quantum Mechanics

    CERN Document Server

    Bub, J; Goldstein, S; Bub, Jeffrey; Clifton, Rob; Goldstein, Sheldon

    1999-01-01

    We show that the Bub-Clifton uniqueness theorem for 'no collapse' interpretations of quantum mechanics (Studies in the History and Philosophy of Modern Physics 27, 181-219 (1996)) can be proved without the 'weak separability' assumption.

  1. Prevalence of gestational diabetes mellitus, its associated risk factors and pregnancy outcomes at a rural setup in Central India

    Directory of Open Access Journals (Sweden)

    Kanika R. Kalyani

    2014-02-01

    Conclusion: GDM adversely affects maternal and fetal outcomes and its prevalence is steadily rising. Appropriate interventions are required for its control. [Int J Reprod Contracept Obstet Gynecol 2014; 3(1.000: 219-224

  2. Department of Zoological Science

    African Journals Online (AJOL)

    USER

    2017-03-10

    Mar 10, 2017 ... Ethiopian Journal of Environmental Studies & Management 10(2): 219 – 228, ... This showed diversity of all the guilds did have significant positive ... of the regulatory effects of birds on ..... Guild of the Carnivore Community.

  3. Ühiskonna kihistumine kui raskendav tegur riigi suhtlemisel rahvaga / Agu Uudelepp

    Index Scriptorium Estoniae

    Uudelepp, Agu, 1974-

    2002-01-01

    Bibliogr. lk. 219. Poliitikud peaksid rahvaga rääkides arvestama 4 etappi: veenmise eeltöö, usaldusväärsuse saavutamine, sõnumi koostamine ja edastamisviisi valimine ning emotsioonide äratamine

  4. Symmetry adaptation of spherical tensor quantities in cubic point groups: comments on a paper by M. Rey et al.

    Science.gov (United States)

    Michelot, F.

    2004-04-01

    We underline some inconsistencies in the work [J. Mol. Spectrosc. 219 (2003) 313] concerning symmetry adaptation in cubic groups. Also we show that some rather complicated methods presented can be easily avoided.

  5. Oceanographic data acquired in support of the June 1980 study of the upwelling center off Point Sur, California (NODC Accession 9000024)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Current, Temperature and Depth (CTD) data were collected by Naval Postgraduate School from Coastal Waters of California between 2-19 June, 1980 using ship...

  6. Enhancement of the feeding value of wheat offal for broiler feeding ...

    African Journals Online (AJOL)

    Dr. &Mrs Tunde Lawal

    2012-08-14

    Aug 14, 2012 ... 3Department of Animal Production and Health, Ladoke Akintola University of Science and Technology, ... The relative cost benefit (RCB) showed that economically, the birds .... The author did it for cocoa shell and 21.9%.

  7. An open-label study to assess the effect of a single dose of Nebivolol and Ivabradine on heart rate and pulse wave velocity in hypertensive patients receiving amlodipine

    Directory of Open Access Journals (Sweden)

    Rama Mohan Pathapati

    2015-04-01

    Conclusions: Nebivolol is an effective HR lowering agent compared to Ivabradine. However, significant decrease in arterial stiffness was observed with Ivabradine. [Int J Basic Clin Pharmacol 2015; 4(2.000: 219-223

  8. Disease: H00116 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00116 Congenital lactase deficiency; Disaccharide intolerance II Congenital lactas...6060 Swallow DM Genetics of lactase persistence and lactose intolerance. Annu Rev Genet 37:197-219 (2003) ...

  9. 78 FR 77710 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-12-24

    ...., Bridgeport, 13001049 Brown--Henry House, 818 Fields Ave., Frankfort, 13001050 Point Breeze, 219 Riverview St... Madison County Churchill Weavers, 100 Churchill Dr., Berea, 13001054 Trimble County Norfolk Farm...

  10. Gene : CBRC-ACAR-01-0376 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available 219.3| AGAP008244-PA [Anopheles gambiae str. PEST] gb|EAL39610.3| AGAP008244-PA [Anopheles gambiae str. PEST...GTIAGTSESPRAQETTSLKSTKTPTSESTTLSETTSLERTIEGISESTVVQETTSLETTTAATTLSSRAQEITSPESTKIP...TSESTTLSETTSSESAMSATTESPRAQETTSPDITTAATSESTTLSEKTSPESTIAGTSQSTVVQETTSPEGTIAATSESPKAQETTSPESTKTAASESTPLPKTVSPEST...ITGRSESTIVQETTSPDGTTAATSESTVVQETTSPESTTAATSESPRAQETTSPESTTAATPESSKLSETTSPESTIAGTSQSTVVQETTSPDSTTAATSESQRAHKTTSPEST...KTAKSESTTVSVTISPECTIAGTSESTVVQKNTFPESTTAATSESTPLSETTSPESTIARTSESIVVQETTSPEST

  11. Design of 16S rRNA gene primers for 454 pyrosequencing of the human foregut microbiome

    National Research Council Canada - National Science Library

    Nossa, Carlos W; Oberdorf, William E; Yang, Liying; Aas, Jørn A; Paster, Bruce J; Desantis, Todd Z; Brodie, Eoin L; Malamud, Daniel; Poles, Michael A; Pei, Zhiheng

    2010-01-01

    .... A foregut microbiome dataset was constructed using 16S rRNA gene sequences obtained from oral, esophageal, and gastric microbiomes produced by Sanger sequencing in previous studies represented by 219 bacterial species...

  12. CAUSING OBSTRICTIVE HYDROCEPHALUS

    African Journals Online (AJOL)

    tions regarding their treatment difhcult and as- signment of prognostic .... gical intervention and the appropriate technology ... (To the nursing staff for taking care of the patient. We are also ... treat- ment. New York, Raven Press 1994; 2 : 219-.

  13. 75 FR 28019 - Resmethrin; Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-05-19

    ..., recreational, and residential areas to control flying and crawling insects. All remaining resmethrin end use... reproduction 2.1.7 Hershberger (rat) 2.1.8 Female Pubertal (rat) 2.1.9 Male pubertal (rat)...

  14. Why Are Drugs So Hard to Quit?

    Medline Plus

    Full Text Available ... a control tower that sends out signals to direct your actions and choices. Addiction changes the signals ... 02. TEDMED 217,219 views 19:02 The Science of Addiction: Here's Your Brain on Drugs | National ...

  15. Molecular and biological characterization of a new Tomato mild yellow leaf curl Aragua virus strain producing severe symptoms in tomato.

    Science.gov (United States)

    Romay, Gustavo; Chirinos, Dorys T; Geraud-Pouey, Francis; Gillis, Annika; Mahillon, Jacques; Desbiez, Cécile; Bragard, Claude

    2017-06-20

    Tomato mild yellow leaf curl Aragua virus (ToMYLCV) is a begomovirus first reported infecting tomato (Solanum lycopersicum) and milkweed (Euphorbia heterophylla) in Venezuela. In this study, a ToMYLCV isolate (Zulia-219) was completely sequenced and its host range was evaluated. The DNA-A and DNA-B components of isolate Zulia-219 showed 93 and 85% nucleotide sequence identity with the respective counterparts of the ToMYLCV type strain. According to current demarcation criteria for begomovirus species, Zulia-219 is a new strain of ToMYLCV. Interestingly, tomato plants inoculated with ToMYLCV Zulia-219 displayed severe symptoms, including severe chlorotic leaf curling, in contrast to mild symptoms associated with the type strain of this begomovirus. These results indicate potential risks associated with this new ToMYLCV strain for tomato production in Venezuela.

  16. Drug: D09952 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ACE VTHQGLSSPV TKSFNRGEC (Disulfide bridge: 23-93; 139-199; H130-L219, Dimer) Peptide Treatment of Alzheim...er's disease monoclonal antibody beta-amyloid CAS: 1178862-65-1 PubChem: 124490631 ...

  17. 76 FR 69801 - Conductor Certification

    Science.gov (United States)

    2011-11-09

    ... definition of ``conductor'' is a fundamental element of the conductor certification regulation and FRA does... and 219. G. Vision and Hearing Acuity BLET/UTU commented that proposed Sec. 242.117(k) should...

  18. Dicty_cDB: SFH109 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available musculus cDNA clone IMAGE:3468576 3', mRNA sequence. 38 0.11 2 CF390442 |CF390442.1 RTDR2_19_F09.g1_A021 Loblolly pine roots recover...ing from drought DR2 Pinus taeda cDNA clone RTDR2_19_F09_A021 5', mRNA sequence. 34

  19. 76 FR 59578 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2011-09-27

    ... 243 Rolls Royce Bentley Turbo R......... 1992-1993 291 Rolls Royce Phantom 2004 455 Saab 9.3 2003 426 Saab 9000 1988 59 Saab 9000 1994 334 Saab 900 S 1987-1989 270 Saab 900 SE 1995 213 Saab 900 SE 1990-1994 219 Saab 900 SE 1996-1997 219 Smart Car Fortwo (incl. trim Coupe & Cabriolet....... 2005 30 levels...

  20. AcEST: DK954327 [AcEST

    Lifescience Database Archive (English)

    Full Text Available --SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 308 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSIS...11%) Frame = +2 Query: 287 PSSPSVSAPQKLSILA------SALNGCQPNYKPSIRASLYYPFEPYSISLVHL 430 P P + A Q+ ++A S L+ P ...|B3PRV4_RHIE6 Putative metalloprotease protein OS=Rhizo... 34 6.3 tr|B8CBD2|B8CBD2_THAPS Predicted protein OS=Thalassiosira...QAFCQVSLLDHSRTCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 211 Query: 308 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 42...Sbjct: 165 GQRYVWMETQQAFCQVSLLDHGRTCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 308 APQKLSILA-SALNGCQPNYKPSIRA

  1. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    Energy Technology Data Exchange (ETDEWEB)

    Nicholas, R.G.; Lacy, N.H.; Butz, T.R.; Brandon, N.E.

    2004-10-06

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  2. Mechanisms of protein sequence divergence and incompatibility.

    Directory of Open Access Journals (Sweden)

    Alon Wellner

    Full Text Available Alignments of orthologous protein sequences convey a complex picture. Some positions are utterly conserved whilst others have diverged to variable degrees. Amongst the latter, many are non-exchangeable between extant sequences. How do functionally critical and highly conserved residues diverge? Why and how did these exchanges become incompatible within contemporary sequences? Our model is phosphoglycerate kinase (PGK, where lysine 219 is an essential active-site residue completely conserved throughout Eukaryota and Bacteria, and serine is found only in archaeal PGKs. Contemporary sequences tested exhibited complete loss of function upon exchanges at 219. However, a directed evolution experiment revealed that two mutations were sufficient for human PGK to become functional with serine at position 219. These two mutations made position 219 permissive not only for serine and lysine, but also to a range of other amino acids seen in archaeal PGKs. The identified trajectories that enabled exchanges at 219 show marked sign epistasis - a relatively small loss of function with respect to one amino acid (lysine versus a large gain with another (serine, and other amino acids. Our findings support the view that, as theoretically described, the trajectories underlining the divergence of critical positions are dominated by sign epistatic interactions. Such trajectories are an outcome of rare mutational combinations. Nonetheless, as suggested by the laboratory enabled K219S exchange, given enough time and variability in selection levels, even utterly conserved and functionally essential residues may change.

  3. Liquid Scintillation Counting of Environmental Radioisotopes: A Review of the Impact of Background Reduction

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, Matthew; Bernacki, Bruce E.; Erchinger, Jennifer L.; Finn, Erin C.; Fuller, Erin S.; Hoppe, Eric W.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Orrell, John L.; Panisko, Mark E.; Warren, Glen A.; Wright, Michael E.

    2016-03-09

    Liquid scintillation counting (LSC) is a versatile and commonplace method for radiometric measurement of charged particle emitting radionuclides. The LSC method provides utility in a range of environmental science applications including hydrological studies of water transport, anthropogenic releases of radionuclides into the environment, and vertical mixing rates within oceans. Instrumental measurement background is one limiting factor of radiometric measurement sensitivity. As part of the development of a custom low background LSC system located in a shallow underground laboratory at Pacific Northwest National Laboratory, a number of measurement applications of LSC have been considered and are summarized here. The focus is on determining which aspects of such measurements would gain the greatest benefit from the reduction of LSC backgrounds by a factor of 10-100 relative to values reported in the literature. Examples of benefits include lowering the minimum detectable activity, reducing the sample size required, and shortening the elapsed timeline of the processing and analysis sequence. In particular tritium, strontium, and actinium isotopes are examined as these isotopes cover a range of requirements related to the LSC measurement method (e.g., 3H: low energy; Sr: spectral deconvolution; Ac: alpha/beta discrimination).

  4. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  5. Rutherford's curriculum vitae, 1894-1907.

    Science.gov (United States)

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus.

  6. Development of an Ultra-Low Background Liquid Scintillation Counter for Trace Level Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Erchinger, Jennifer L.; Orrell, John L.; Aalseth, Craig E.; Bernacki, Bruce E.; Douglas, Matthew; Finn, Erin C.; Fuller, Erin S.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Panisko, Mark E.; Shaff, Sarah M.; Warren, Glen A.; Wright, Michael E.

    2015-09-01

    Low-level liquid scintillation counting (LSC) has been established as one of the radiation detection techniques useful in elucidating environmental processes and environmental monitoring around nuclear facilities. The Ultra-Low Background Liquid Scintillation Counter (ULB-LSC) under construction in the Shallow Underground Laboratory at Pacific Northwest National Laboratory aims to further reduce the MDAs and/or required sample processing. Through layers of passive shielding in conjunction with an active veto and 30 meters water equivalent overburden, the background reduction is expected to be 10 to 100 times below typical analytic low-background liquid scintillation systems. Simulations have shown an expected background of around 14 counts per day. A novel approach to the light collection will use a coated hollow light guide cut into the inner copper shielding. Demonstration LSC measurements will show low-energy detection, spectral deconvolution, and alpha/beta discrimination capabilities, from trials with standards of tritium, strontium-90, and actinium-227, respectively. An overview of the system design and expected demonstration measurements will emphasize the potential applications of the ULB-LSC in environmental monitoring for treaty verification, reach-back sample analysis, and facility inspections.

  7. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    NA

    2004-11-22

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this modeling activity is to predict dissolved concentrations or solubility limits for 14 elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) important to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are in the form of tabulated functions with pH and log (line integral) CO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. The output data from this report are fundamental inputs for Total System Performance Assessment for the License Application (TSPA-LA) to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for all of the actinides. These models cover broad ranges of environmental conditions so that they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or otherwise addressed.

  8. Purification of lanthanides for double beta decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Polischuk, O. G. [Institute for Nuclear Research, MSP 03680 Kyiv, Ukraine and INFN, Section of Rome, La Sapienza, I-00185 Rome (Italy); Barabash, A. S. [Institute of Theoretical and Experimental Physics, 117259 Moscow (Russian Federation); Belli, P. [INFN, Section of Rome Tor Vergata, I-00133 Rome (Italy); Bernabei, R. [INFN, Section of Rome Tor Vergata, I-00133 Rome, Italy and Department of Physics, University of Rome Tor Vergata, I-00133 Rome (Italy); Boiko, R. S.; Danevich, F. A.; Mokina, V. M.; Poda, D. V.; Tretyak, V. I. [Institute for Nuclear Research, MSP 03680 Kyiv (Ukraine); Cappella, F.; Incicchitti, A. [INFN, Section of Rome La Sapienza, I-00185 Rome, Italy and Department of Physics, University of Rome La Sapienza, I-00185 Rome (Italy); Cerulli, R.; Laubenstein, M.; Nisi, S. [INFN, Gran Sasso National Laboratories, I-67100 Assergi (Aq) (Italy)

    2013-08-08

    There are several potentially double beta active isotopes among the lanthanide elements. However, even high purity grade lanthanide compounds contain {sup 238}U, {sup 226}Ra and {sup 232,228}Th typically on the level of ∼ (0.1 - 1) Bq/kg. The liquid-liquid extraction technique was used to remove traces of U, Ra and Th from CeO{sub 2}, Nd{sub 2}O{sub 3} and Gd{sub 2}O{sub 3}. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe γ spectrometry at the underground Gran Sasso National Laboratories of the INFN (Italy). After the purification the radioactive contamination of gadolinium oxide by Ra and Th was decreased at least one order of magnitude. The efficiency of the approach to purify cerium oxide from Ra was on same level, while the radioactive contamination of neodymium sample before and after the purification is below the sensitivity of analytical methods. The purification method is much less efficient for chemically very similar radioactive elements like lanthanum, lutetium and actinium. R and D of the methods to remove the pollutions with improved efficiency is in progress.

  9. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin.

    Science.gov (United States)

    Nour, S; El-Sharkawy, A; Burnett, W C; Horwitz, E P

    2004-12-01

    The objective of this work was to establish a new procedure for 228Ra determination of natural waters via preconcentration of radium on MnO2 and separation of its daughter, 228Ac, using Diphonix ion exchange resin. Following removal of potential interferences via passage through an initial Diphonix Resin column, the first daughter of 228Ra, 228Ac, is isolated by chromatographic separation via a second Diphonix column. A holding time of > 30 h for 228Ac ingrowth in between the two column separations ensures secular equilibrium. Barium-133 is used as a yield tracer. Actinium-228 is eluted from the second Diphonix Resin with 5 ml 1M 1-Hydroxyethane-1,1-diphosphonic acid (HEDPA) and quantified by addition of scintillation cocktail and LSC counting. Radium (and 133Ba) from the load and rinse solutions from the 2nd Diphonix column may be prepared for alpha spectrometry (for determination of 223Ra, 224Ra, and 226Ra) by BaSO4 microprecipitation and filtration. Decontamination tests indicate that U, Th, and Ra series nuclides do not interfere with these measurements, although high contents of 90Sr (90Y) require additional treatment for accurate measurement of 228Ra. Addition of stable Sr as a "hold back" carrier during the initial MnO2 preconcentration step was shown to remove most 90Sr interference.

  10. Soil and river sediments radionuclides monitoring at Aramar Experimental Center: an historical overview

    Energy Technology Data Exchange (ETDEWEB)

    Segre, Nadia; Fagundes, Rosane Correa, E-mail: nadia.segre@ctmsp.mar.mil.br [Centro Tecnologico da Marinha (CTM-SP/CEA/LARE), Ipero, SP (Brazil). Centro Experimental Aramar. Lab. Radioecologico; Moraes, Marco Antonio P.V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    In order to evaluate possible effects to the environment resulting from the implementation of the Centro Tecnologico da Marinha - Centro Experimental Aramar (CTMSP-CEA) at Ipero in Sao Paulo state, Brazil, which came into operation in 1989, an Environmental Monitoring Program (PMA) was established in October, 1987. One of the aims of this program is to monitor the soil and river sediments radionuclides levels at CEA and beyond its boundary. The utilization of statistical tools to evaluate the results of radiometric environmental monitoring is a procedure required by National Nuclear Energy Commission (CNEN). The box plot is a simple statistical tool for displaying data. The central tendency and dispersion of the results as well as the observation of unusual results (outliers) in the dataset are easily visualized. Control chart is a graph that maps data and provides a picture of how a process is performing over time. A control chart always has a central line for the mean, an upper line for the upper control limit and a lower line for the lower control limit. Box plots and control charts were used to visualize the annual amount of natural uranium, lead-214, actinium-228 and lead-212 in soil and river sediment detected between 1987 and 2011, considering the measurements of all monitored places each year. This historical observation shows that, in average, the results obtained are below than the 1987-1988 levels (CEA's pre-operational) or below than the backgrounds radionuclides values. (author)

  11. Background radiation and individual dosimetry in the costal area of Tamil Nadu, India.

    Science.gov (United States)

    Matsuda, Naoki; Brahmanandhan, G M; Yoshida, Masahiro; Takamura, Noboru; Suyama, Akihiko; Koguchi, Yasuhiro; Juto, Norimichi; Raj, Y Lenin; Winsley, Godwin; Selvasekarapandian, S

    2011-07-01

    South coast of India is known as the high-level background radiation area (HBRA) mainly due to beach sands that contain natural radionuclides as components of the mineral monazite. The rich deposit of monazite is unevenly distributed along the coastal belt of Tamil Nadu and Kerala. An HBRA site that laid in 2×7 m along the sea was found in the beach of Chinnavillai, Tamil Nadu, where the maximum ambient dose equivalent reached as high as 162.7 mSv y(-1). From the sands collected at the HBRA spot, the high-purity germanium semi-conductor detector identified six nuclides of thorium series, four nuclides of uranium series and two nuclides belonging to actinium series. The highest radioactivity observed was 43.7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1).

  12. Coupling of Uranium and Thorium Series Isotope Systematics for Age Determination of Late Pleistocene Zircons using LA-ICP-MS

    Science.gov (United States)

    Sakata, S.; Hirakawa, S.; Iwano, H.; Danhara, T.; Hirata, T.

    2014-12-01

    Zircon U-Th-Pb dating method is one of the most important tools for estimating the duration of magmatism by means of coupling of uranium, actinium and thorium decay series. Using U-Pb dating method, its reliability is principally guaranteed by the concordance between 238U-206Pb and 235U-207Pb ages. In case of dating Quaternary zircons, however, the initial disequilibrium effect on 230Th and 231Pa should be considered. On the other hands, 232Th-208Pb dating method can be a simple but powerful approach for investigating the age of crystallization because of negligible influence from initial disequilibrium effect. We have developed a new correction model for accurate U-Pb dating of the young zircon samples by taking into consideration of initial disequilibrium and a U-Pb vs Th-Pb concordia diagram for reliable age calibration was successfully established. Hence, the U-Th-Pb dating method can be applied to various zircons ranging from Hadean (4,600 Ma) to Quaternary (~50 ka) ages, and this suggests that further detailed information concerning the thermal history of the geological sequences can be made by the coupling of U-Th-Pb, fission track and Ar-Ar ages. In this presentation, we will show an example of U-Th-Pb dating for zircon samples from Sambe Volcano (3 to 100 ka), southwest Japan and the present dating technique using LA-ICP-MS.

  13. Pulse-shape discrimination and energy quenching of alpha particles in Cs$_2$LiLaBr$_6$:Ce$^{3+}$

    CERN Document Server

    Mesick, Katherine E; Stonehill, Laura C

    2016-01-01

    Cs$_2$LiLaBr$_6$:Ce$^{3+}$ (CLLB) is an elpasolite scintillator that offers excellent linearity and gamma-ray energy resolution and sensitivity to thermal neutrons with the ability to perform pulse-shape discrimination (PSD) to distinguish gammas and neutrons. Our investigation of CLLB has indicated the presence of intrinsic radioactive alpha background that we have determined to be from actinium contamination of the lanthanum component. We measured the pulse shapes for gamma, thermal neutron, and alpha events and determined that PSD can be performed to separate the alpha background with a moderate figure of merit of 0.98. We also measured the electron-equivalent-energy of the alpha particles in CLLB and simulated the intrinsic alpha background from $^{227}$Ac to determine the quenching factor of the alphas. A linear quenching relationship $L_{\\alpha} = E_{\\alpha} \\times q + L_0$ was found at alpha particle energies above 5 MeV, with a quenching factor $q = 0.71$ MeVee/MeV and an offset $L_0 = - 1.19$ MeVee.

  14. Cyclotron production of cesium radionuclides as analogues for francium-221 biodistribution

    Science.gov (United States)

    Finn, R.; McDevitt, M.; Sheh, Y.; Lom, C.; Qiao, J.; Cai, S.; Burnazi, E.; Nacca, A.; Pillarsetty, N.; Jaggi, J.; Scheinberg, D.

    2005-12-01

    In our clinical investigations focussing on improved therapeutic treatment of specific tumors we have concentrated on a targeted therapy approach utilizing designed radiolabeled monoclonal antibodies as the cytotoxic reagent. The physical characteristics of the alpha particle emitting radionuclide bismuth-213 including the short half-life of 45.6 min, has shown promise for the treatment of specific cancers such as leukemias and lymphomas or micrometastatic carcinomas. In an effort to increase the cytocidal effect of the HuM195, a humanized monoclonal antibody carrier to the CD33 antigen expressed on leukemia cells, our focus is directed toward an "internal" nano-generator composed of Ac-225 radionuclide, the parent of the bismuth-213. The actinium-225 radionuclide decays through several short-lived, alpha emitting daughters including francium-221, astatine-217 and bismuth-213. In order to study the biodistribution and the pharmacokinetics of the individual daughter nuclide, francium-221, the cyclotron production and separation of cesium radionuclides, specifically cesium-132, from a natural xenon gas target was undertaken. The choice of cesium as an analogue for francium was predicated upon both elements being in Group 1A alkali metals and cesium radionuclide possesses a sufficient half-life to allow biodistribution studies to be performed. The preliminary experimental results of this investigation are presented.

  15. An Ion Exchange Study of Possible Hydridized 5f Bonding in theActinides

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, R.M.; Street, Jr., K.; Seaborg, G.T.

    1951-08-28

    A study has been made of the elution behavior of curium(III), americium(III), plutonium(III), actinium(III), plutonium(IV), neptunium(IV), uraniuM(IV), thorium(IV), neptunium(V), plutonium (VI), uranium (VI), lanthanum(III), cerium(III), europium(III), ytterbium(III), ytterium(III), strontium(II), barium(II), radium(II), cesium(I) with 3.2 M, 6.2 M, 9.3 M, and 12.2 M HCl solutions from Dowex-50 cation exchange resin columns. These elutions show that in high concentrations of hydrochloric acid the actinides form complex ions with chloride ion to a much greater extent than the lanthanides. The strengths of the tripositive actinide complex ions apparently go in the order plutonium > americium> curium, although their ionic radii also decrease in this same order. To explain these results, a partial covalent character may be ascribed to the bonding in the transuranium complex ions. It is shown that a reasonable structure for such covalent bonding involves hybridization of the 5f orbitals in the actinide elements.

  16. Electronic structure and dynamics of ordered clusters with ME or RE ions on oxide surface

    Energy Technology Data Exchange (ETDEWEB)

    Kulagin, N.A., E-mail: nkulagin@bestnet.kharkov.u [Kharkiv National University for Radio Electronics, Avenue Shakespeare 6-48, 61045 Kharkiv (Ukraine)

    2011-03-15

    Selected data of ab initio simulation of the electronic structure and spectral properties of either cluster with ions of iron, rare earth or actinium group elements have been presented here. Appearance of doped Cr{sup +4} ions in oxides, Cu{sup +2} in HTSC, Nd{sup +2} in solids has been discussed. Analysis of experimental data for plasma created ordered structures of crystallites with size of about 10{sup -9} m on surface of separate oxides are given, too. Change in the spectroscopic properties of clusters and nano-structures on surface of strontium titanate crystals discussed shortly using the X-ray line spectroscopy experimental results. - Research highlights: External influence and variation of technology induce changes in valence of nl ions in compounds. Wave function of cluster presented as anti-symmetrical set of ions wave functions. The main equation describes the self-consistent field depending on state of all electrons of cluster. Level scheme of Cr{sup 4+} ions in octo- and tetra-site corresponds to doped oxides spectra after treatment. Plasma treatment effects in appearance of systems of unit crystallites with size of about 10{sup -6}-10{sup -9} m.

  17. Clinical evaluation of Xive implants 3-year after placement

    Institute of Scientific and Technical Information of China (English)

    Ruixia Wang; Hua Yuan; Ning Chen; Guoping Wang; Zhaoping Fang; Guoxing Zhou

    2008-01-01

    Objective: The main purpose of this retrospective study is to evaluate clinical outcomes of Xive implants 3-year after insertion. Methods: 219 Xive implants were placed in 139 patients and their clinical effects were evaluated using the Albrektsson Standard. Results:The 3-year survival rate of the Xive implants is 97.26%(213/219). Eleven cases of immediate implants and 15 cases of implant insertion after maxillary sinus lifting all succeeded. The failure ratio is 6/219(2.74%) with failures resulting from excess bone loss in the implant region, peal-implant mucosal inflammation or continuous pain caused by some unknown reasons. Conclusion: Xive implants are clinically effective for the restoration of missing teeth. Immediate implant and implant following maxillary sinus lifting were also successful.

  18. Elsevier收录材料科学类期刊可开放获取情况的调查与分析

    Institute of Scientific and Technical Information of China (English)

    何燕; 瞿其春; 张雪娟

    2014-01-01

    对Elsevier旗下的SDOL数据库中的219种材料科学类期刊进行有关OA方面的研究,调查发现,在OSD和DOAJ这两大OA平台上,这219种期刊的可OA情况不容乐观。在SDOL数据库中,可OA的材料科学类期刊种数为数不少,但其中可OA期刊全文的并不多。将这219种期刊区分为完全OA期刊、部分OA期刊和完全非OA期刊,并对其质量进行了对比研究,认为Elsevier中材料科学类期刊的OA情况不是十分乐观,需业界的进一步推动。

  19. Efficient callus formation and plant regeneration are heritable characters in sugar beet (Beta vulgaris L.).

    Science.gov (United States)

    Kagami, Hiroyo; Taguchi, Kazunori; Arakawa, Takumi; Kuroda, Yosuke; Tamagake, Hideto; Kubo, Tomohiko

    2016-01-01

    Obtaining dedifferentiated cells (callus) that can regenerate into whole plants is not always feasible for many plant species. Sugar beet is known to be recalcitrant for dedifferentiation and plant regeneration. These difficulties were major obstacles for obtaining transgenic sugar beets through an Agrobacterium-mediated transformation procedure. The sugar beet line 'NK-219mm-O' is an exceptional line that forms callus efficiently and is easy to regenerate, but the inheritance of these characters was unknown. Another concern was whether these characters could coexist with an annual habitat that makes it possible to breed short life-cycle sugar beet suitable for molecular genetic analysis. Five sugar beet lines including NK-219mm-O were crossed with each other and subjected to in vitro culture to form callus. F1s with a NK-219mm-O background generally formed callus efficiently compared to the others, indicating that efficient callus formation is heritable. The regeneration potential was examined based on the phenotypes of calli after placement on regeneration medium. Five phenotypes were observed, of which two phenotypes regenerated shoots or somatic embryo-like structures. Vascular differentiation was evident in regenerable calli, whereas non-regenerable calli lacked normally developed vascular tissues. In a half-diallel cross, the callus-formation efficiency and the regeneration potential of reciprocal F1s progeny having a NK-219mm-O background were high. Finally, we crossed NK-219mm-O with an annual line that had a poor in vitro performance. The callus-formation efficiency and the regeneration potential of reciprocal F1 were high. The regenerated plants showed an annual habitat. Efficient callus formation and the high plant regeneration potential of NK-219mm-O were inherited and expressed in the F1. The annual habitat does not impair these high in vitro performances.

  20. Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - the Cardiovascular Risk in Young Finns study.

    Science.gov (United States)

    Tolonen, Sanna; Mikkilä, Vera; Laaksonen, Marika; Sievänen, Harri; Mononen, Nina; Hernesniemi, Jussi; Vehkalahti, Kimmo; Viikari, Jorma; Raitakari, Olli; Kähönen, Mika; Lehtimäki, Terho

    2011-05-01

    Association of apolipoprotein E (APOE) ε4 allele with peripheral quantitative computed tomography (pQCT) bone traits at the distal and shaft sites of the radius and tibia was evaluated in the Young Finns Cohort (n=1777). We also analyzed the interactions of the APOE promoter polymorphisms (-219G/T rs405509 and +113G/C rs440446) and bone traits within the APOE ε3/ε3 genotype (n=1025 and n=1013, respectively), and investigated the gene-environment interactions on bone traits with longitudinal saturated fatty acids (SAFA) intake. Differences between the ε4 allele carriers and noncarriers were modest and mostly nonsignificant. Within the APOE promoter -219G/T polymorphism, cortical strength index (CSI) and compressive bone strength index (BSI) at the distal radius (linear, P=0.003 and P=0.05, respectively) and tibia (linear, P=0.01 and P=0.03, respectively), and CSI at the tibial shaft (linear, P=0.04) decreased towards the -219T/T genotype in women. In men, total cross-sectional areas at the radial site and stress-strain index (SSI) at the radial shaft (linear, P=0.03 and P=0.04 and P=0.05, respectively) increased, and conversely cortical bone density and CSI at the radial shaft (linear, P=0.005 and P=0.05, respectively) and CSI at the tibial shaft (linear, P=0.03) decreased towards the -219T/T genotype. In the highest SAFA tertile, women with the -219T/T genotype had the smallest total area and SSI at the radial shaft (P=0.01 and P=0.02, respectively). Subjects with the APOE +113C/C genotype shared similar bone traits as subjects with the APOE -219T/T genotype. In conclusion, APOE genotypes -219T/T and +113C/C could be genetic markers for cortical bone strength. Furthermore, high longitudinal SAFA intake seems to be more detrimental to bone in women with the -219T/T and +133C/C genotypes than others. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. Dollar Summary of Prime Contract Awards by State, Place, and Contractor, FY84, Part 3, (Anderson, Indiana-Winona, Mississippi).

    Science.gov (United States)

    1984-01-01

    64 64 GERHARDTS INC 95 95 GIBBS CONSTRUCTION CO INC 1,286 1,286 GOTTFRIED CORPORATION THE 196 196 GOULD COMPUTER SYSTEMS INC 42 42 GREAT LAKES DREDGE...BA RALPHS CLIMATE CONTROL 38 38 REGLAS PAINTING COMPANY INC 31 31 ROCKWELL INTERNATIONAL CORP 105 105 RONIKE FOAM INSULATORS INC 334 334 ROUSSOS...232 GIBBS A HILL INC 219 219 IMBRACSIO, J & SONS 166 18 JET AVIATION OF AMERICA INC 33 33 KALLEN & LEMELSON 202 202 LANIER BUSINESS PRODUCTS INC 66 Be

  2. Band gap tuning of amorphous Al oxides by Zr alloying

    DEFF Research Database (Denmark)

    Canulescu, Stela; Jones, N. C.; Borca, C. N.

    2016-01-01

    The optical band gap and electronic structure of amorphous Al-Zr mixed oxides, with Zr content ranging from4.8 to 21.9% were determined using vacuum ultraviolet (VUV) and X-ray absorption spectroscopy (XAS). Thelight scattering by the nano-porous structure of alumina at low wavelengths was estima......The optical band gap and electronic structure of amorphous Al-Zr mixed oxides, with Zr content ranging from4.8 to 21.9% were determined using vacuum ultraviolet (VUV) and X-ray absorption spectroscopy (XAS). Thelight scattering by the nano-porous structure of alumina at low wavelengths...

  3. Corrosion Control in the US Navy: Ships & USMC Vehicles

    Science.gov (United States)

    2014-11-18

    Mr. Matthew Koch Corrosion Control & Prevention Executive Presented by E. Dail Thomas II, Consultant 18 November 2014 Corrosion Control in...control number. 1. REPORT DATE 18 NOV 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Corrosion Control in...Cost of Corrosion : $21.9B 2 DoD $21.9B $7.5B $5.1B $5.1B $0.3B $4.2B Other DoD U.S. Department of Defense Corrosion Organization 3 ASD

  4. Determination of the Ionosphere Parameters by Analyzing the Propagation After-Effects

    Science.gov (United States)

    2010-06-27

    is a very “lively” medium; its characteristics depend on many factors , such as time of the day, time of the year, geographic location, level of Solar...whereas the long waves are subject to stronger dispersion. Indeed, the phase and group velocity of the propagation are given by: vph = c ( 1 + ω2pe/c...c) |x − y |2 . (2.19) The filter is essentially a complex conjugate of ψ1 given by (2.19); for simplicity, the constant factor −ω20/16π2, as well the

  5. Monolithic Hybrid and Passive Mode-Locked 40GHz Quantum Dot Laser Diodes

    DEFF Research Database (Denmark)

    Thompson, M. G.; Larsson, David; Rae, A. R.

    2006-01-01

    For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs.......For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs....

  6. Academic Research Vessels 1985-1990.

    Science.gov (United States)

    1982-01-01

    0.2 0.05 0.1 EPA 0.1 0.1 0.01 0.1 0.01 NASA 0.08 0.2 ARPA 0.4 State & Private 0.6 1.2 0.9 1.5 1.5 Totals* 21.9 22.8 21.9 25.6 29.4 * Cost of operating...This include no provision for crew layoff . The crew costs for an OCEANUS class vessel are approximately $310,000 for a crew of 12 4 persons. If one

  7. [RH Factor and Clinical Transfusion Effectiveness for β-Thalassemia Children with Long-Term Blood Transfusion].

    Science.gov (United States)

    Wu, Chang-Lin; Wang, Xiao-Hua; He, Jian-An; Gu, Da-Yong; Dang, Xing-Tang; Zhu, Yi; Shao, Chao-Peng

    2015-12-01

    To investigate the irregular antibody production and its relationship with Rh factor genotypes and the loci of thalassemia gene mutations for the β-thalassemic children with long-term transfusion, so as provide experimental basis for clinical safe and effective transfusions for thalassemic children. The peripheral blood from 246 children with β-thalassemia was collected in our hospital; the extraction of genomic DNA and Rh factor (C/c, E/e) genotypes were assayed by PCR-SSP method, the irregular antibodies were screened and identified by serological method, the genotypes for thalassemia and gene mutations were analysed by PCR-RD method. The genotypes of Rh factors classified by PCR- SSP in the 246 cases of β-thalassemia children were as follws: Ce/Ce (143/246, 58.1%), CE/ce (59/246, 24%), cE/cE (14/24, 5.7%), Ce/ce (12/246, 4.9%); The positive rate of irregular antibody was 7.7% (19/246), including anti-E (7/19), anti-c (5/19), anti-C (2/19), anti-E and anti-c (2/19), anti-e (1/19), anti-D (2/19); Of the 19 cases with positive irregular antibody, the genotypings of Rh factor were: Ce/Ce (11/19), CE/ce (2/19), cE/cE (2/19), Ce/ce (2/19), cE/ce (2/19); the gene mutations location of thalassemia for 19 cases with positive irregular antibody: CD41-42M (13/19), CD71-72M (2/19), IVS-II-654M (3/19), -28M (1/19). The irregular antibody production for β-thalassemic children with long-term transfusion may have some relevance with Rh factor genotypes and thalassemia genetic mutations. This study possesses a certain significance for effective prevention of RBC alloimmune response of β-thalassemia children and improvement of efficacy and safety of clinical transfasion blood.

  8. Monolithic Hybrid and Passive Mode-Locked 40GHz Quantum Dot Laser Diodes

    DEFF Research Database (Denmark)

    Thompson, M. G.; Larsson, David; Rae, A. R.;

    2006-01-01

    For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs.......For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs....

  9. AcEST: DK959257 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN Y... (51%), Gaps = 6/54 (11%) Frame = +1 Query: 370 PSSPSVSAPQKLSILA------SALNGCQPNYKPSIRA...alloprotease protein OS=Rhizo... 34 6.7 tr|B8CBD2|B8CBD2_THAPS Predicted protein OS=Thalassiosira pseudo... ...y: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN YY F+ +SI+L Sbjct: 212 VKSYLQLLADEALNP---------...TIYGPNVISIP 219 Query: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN YY F+ +SI+L Sbjct: 220 VKSY

  10. Resposta de plantas micropropagadas de abacaxizeiro à inoculação de bactérias diazotróficas em casa de vegetação Response of pineapple plantlets to inoculation with diazotrophic bacteria in greenhouse

    Directory of Open Access Journals (Sweden)

    Olmar Baller Weber

    2003-12-01

    Full Text Available O objetivo deste trabalho foi selecionar e avaliar bactérias diazotróficas isoladas de abacaxizeiro (Ananas comosus (L. Merril no desenvolvimento de cultivares micropropagadas da mesma espécie em casa de vegetação. Plantas da cultivar Perolera foram submetidas à inoculação com Asaia bogorensis (AB219 e cultivadas em tubetes, durante 145 dias, com as misturas: casca de arroz carbonizada, folha de carnaubeira triturada e vermicomposto; casca de arroz carbonizada, pó da casca do coco maduro e vermicomposto; casca de arroz carbonizada, vermiculita e vermicomposto. Plantas da cultivar Primavera receberam inóculos com o AB219 e bactérias relacionadas a Burkholderia cepacia (AB202 e AB213, enquanto plantas das cultivares Pérola e Smooth Cayenne receberam AB219 e AB213, sendo cultivadas, por 140 dias, em tubetes com a mistura de vermicomposto e vermiculita. A colonização dos abacaxizeiros pelas bactérias diazotróficas foi confirmada. As plantas da cultivar Perolera cresceram melhor em casca de arroz carbonizada, vermiculita e vermicomposto e responderam positivamente ao AB219. Já as plantas da cultivar Primavera não apresentaram resposta significativa à inoculação com AB219, AB202 e AB213. Houve incremento de 23,1% a 38,5% na matéria seca de raízes das plantas da cultivar Pérola na presença de AB213 e AB219, respectivamente. A presença de AB213 incrementou em 15,2% a matéria seca da parte aérea das plantas da cultivar Smooth Cayenne. Os resultados revelam a eficiência de bactérias diazotróficas na promoção do crescimento de abacaxizeiros.The objective of this work was to select and to evaluate isolates of diazotrophic bacteria associated to pineapple (Ananas comosus (L. Merril plants in the development of micropropagated plantlets of cultivars pineapple in greenhouse. Plantlets from the Perolera cultivar have been submitted to inoculation with Asaia bogorensis (AB219 and were cultivated during 145 days on the following

  11. An aerial radiological survey of the Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Hendricks, T J; Riedhauser, S R

    1999-12-01

    A team from the Remote Sensing Laboratory conducted an aerial radiological survey of the US Department of Energy's Nevada Test Site including three neighboring areas during August and September 1994. The survey team measured the terrestrial gamma radiation at the Nevada Test Site to determine the levels of natural and man-made radiation. This survey included the areas covered by previous surveys conducted from 1962 through 1993. The results of the aerial survey showed a terrestrial background exposure rate that varied from less than 6 microroentgens per hour (mR/h) to 50 mR/h plus a cosmic-ray contribution that varied from 4.5 mR/h at an elevation of 900 meters (3,000 feet) to 8.5 mR/h at 2,400 meters (8,000 feet). In addition to the principal gamma-emitting, naturally occurring isotopes (potassium-40, thallium-208, bismuth-214, and actinium-228), the man-made radioactive isotopes found in this survey were cobalt-60, cesium-137, europium-152, protactinium-234m an indicator of depleted uranium, and americium-241, which are due to human actions in the survey area. Individual, site-wide plots of gross terrestrial exposure rate, man-made exposure rate, and americium-241 activity (approximating the distribution of all transuranic material) are presented. In addition, expanded plots of individual areas exhibiting these man-made contaminations are given. A comparison is made between the data from this survey and previous aerial radiological surveys of the Nevada Test Site. Some previous ground-based measurements are discussed and related to the aerial data. In regions away from man-made activity, the exposure rates inferred from the gamma-ray measurements collected during this survey agreed very well with the exposure rates inferred from previous aerial surveys.

  12. Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization.

    Directory of Open Access Journals (Sweden)

    Jaspreet Singh Jaggi

    Full Text Available BACKGROUND: Abnormal regulation of angiogenesis in tumors results in the formation of vessels that are necessary for tumor growth, but compromised in structure and function. Abnormal tumor vasculature impairs oxygen and drug delivery and results in radiotherapy and chemotherapy resistance, respectively. Alpha particles are extraordinarily potent, short-ranged radiations with geometry uniquely suitable for selectively killing neovasculature. METHODOLOGY AND PRINCIPAL FINDINGS: Actinium-225 ((225Ac-E4G10, an alpha-emitting antibody construct reactive with the unengaged form of vascular endothelial cadherin, is capable of potent, selective killing of tumor neovascular endothelium and late endothelial progenitors in bone-marrow and blood. No specific normal-tissue uptake of E4G10 was seen by imaging or post-mortem biodistribution studies in mice. In a mouse-model of prostatic carcinoma, (225Ac-E4G10 treatment resulted in inhibition of tumor growth, lower serum prostate specific antigen level and markedly prolonged survival, which was further enhanced by subsequent administration of paclitaxel. Immunohistochemistry revealed lower vessel density and enhanced tumor cell apoptosis in (225Ac-E4G10 treated tumors. Additionally, the residual tumor vasculature appeared normalized as evident by enhanced pericyte coverage following (225Ac-E4G10 therapy. However, no toxicity was observed in vascularized normal organs following (225Ac-E4G10 therapy. CONCLUSIONS: The data suggest that alpha-particle immunotherapy to neovasculature, alone or in combination with sequential chemotherapy, is an effective approach to cancer therapy.

  13. Evaluation of naturally occurring radioactive materials (NORMs) in inorganic and organic oilfield scales from the Middle East.

    Science.gov (United States)

    Bassioni, Ghada; Abdulla, Fareed; Morsy, Zeinab; El-Faramawy, Nabil

    2012-04-01

    The distribution of natural nuclide gamma-ray activities and their respective annual effective dose rates, produced by potassium-40 (⁴⁰K), uranium-238 (²³⁸U), thorium-232 (²³²Th), and radium-226 (²²⁶Ra), were determined for 14 oilfield scale samples from the Middle East. Accumulated radioactive materials concentrate in tubing and surface equipment, and workers at equipment-cleaning facilities and naturally occurring radioactive materials (NORMs) disposal facilities are the population most at risk for exposure to NORM radiation. Gamma-spectra analysis indicated that photo-gamma lines represent the parents of 10 radioactive nuclides: ²³⁴Th, plutonium-239, actinium-228, ²²⁶Ra, lead-212 (²¹²Pb), ²¹⁴Pb, thallium-238 (²⁰⁸Tl), bismuth-212 (²¹²Bi), ²¹⁴Bi, and ⁴⁰K. These nuclides represent the daughters of the natural radioactive series ²³⁸U and ²³²Th with ⁴⁰K as well. The mean activity concentration of ²³⁸U, ²³²Th, and ⁴⁰K were found to be 25.8 ± 11.6, 18.3 ± 8.1, and 4487.2 ± 2.5% Bq kg⁻¹ (average values for 14 samples), respectively. The annual effective dose rates and the absorbed doses in air, both indoor and outdoor, for the samples were obtained as well. The results can be used to assess the respective hazard on workers in the field and represent a basis for revisiting current engineering practices.

  14. Alpha-emitting isotopes and chromium in a coastal California aquifer

    Science.gov (United States)

    Densmore, Jill N.; Izbicki, John A.; Murtaugh, Joseph M.; Swarzenski, Peter W.; Bullen, Thomas D.

    2014-01-01

    The unadjusted 72-h gross alpha activities in water from two wells completed in marine and alluvial deposits in a coastal southern California aquifer 40 km north of San Diego were 15 and 25 picoCuries per liter (pCi/L). Although activities were below the Maximum Contaminant Level (MCL) of 15 pCi/L, when adjusted for uranium activity; there is concern that new wells in the area may exceed MCLs, or that future regulations may limit water use from the wells. Coupled well-bore flow and depth-dependent water-quality data collected from the wells in 2011 (with analyses for isotopes within the uranium, actinium, and thorium decay-chains) show gross alpha activity in marine deposits is associated with decay of naturally-occurring 238U and its daughter 234U. Radon activities in marine deposits were as high as 2230 pCi/L. In contrast, gross alpha activities in overlying alluvium within the Piedra de Lumbre watershed, eroded from the nearby San Onofre Hills, were associated with decay of 232Th, including its daughter 224Ra. Radon activities in alluvium from Piedra de Lumbre of 450 pCi/L were lower than in marine deposits. Chromium VI concentrations in marine deposits were less than the California MCL of 10 μg/L (effective July 1, 2014) but δ53Cr compositions were near zero and within reported ranges for anthropogenic chromium. Alluvial deposits from the nearby Las Flores watershed, which drains a larger area having diverse geology, has low alpha activities and chromium as a result of geologic and geochemical conditions and may be more promising for future water-supply development.

  15. A survey of arsenic, manganese, boron, thorium, and other toxic metals in the groundwater of a West Bengal, India neighbourhood.

    Science.gov (United States)

    Bacquart, Thomas; Bradshaw, Kelly; Frisbie, Seth; Mitchell, Erika; Springston, George; Defelice, Jeffrey; Dustin, Hannah; Sarkar, Bibudhendra

    2012-07-01

    Around 150 million people are at risk from arsenic-contaminated groundwater in India and Bangladesh. Multiple metal analysis in Bangladesh has found other toxic elements above the World Health Organization (WHO) health-based drinking water guidelines which significantly increases the number of people at risk due to drinking groundwater. In this study, drinking water samples from the Bongaon area (North 24 Parganas district, West Bengal, India) were analyzed for multiple metal contamination in order to evaluate groundwater quality on the neighbourhood scale. Each sample was analyzed for arsenic (As), boron (B), barium (Ba), chromium (Cr), manganese (Mn), molybdenum (Mo), nickel (Ni), lead (Pb), and uranium (U). Arsenic was found above the WHO health-based drinking water guideline in 50% of these tubewells. Mn and B were found at significant concentrations in 19% and 6% of these tubewells, respectively. The maps of As, Mn, and B concentrations suggest that approximately 75% of this area has no safe tubewells. The concentrations of As, Mn, B, and many other toxic elements are independent of each other. The concentrations of Pb and U were not found above WHO health-based drinking water guidelines but they were statistically related to each other (p-value = 0.001). An analysis of selected isotopes in the Uranium, Actinium, and Thorium Radioactive Decay Series revealed the presence of thorium (Th) in 31% of these tubewells. This discovery of Th, which does not have a WHO health-based drinking water guideline, is a potential public health challenge. In sum, the widespread presence and independent distribution of other metals besides As must be taken into consideration for drinking water remediation strategies involving well switching or home-scale water treatment.

  16. The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy

    DEFF Research Database (Denmark)

    Paradowski, P T; Lohmander, Stefan; Englund, Martin Kristian

    2013-01-01

    OBJECTIVE: To examine whether the ratio of the second and fourth metacarpal bone length (MC2:MC4) in subjects with prior meniscectomy of the knee is associated with radiographic hand and knee osteoarthritis (OA) and its progression. DESIGN: We assessed 219 subjects (175 men and 44 women) twice...

  17. 16 CFR 1512.5 - Requirements for braking system.

    Science.gov (United States)

    2010-01-01

    ... highest gear ratio at a pedal crank rate of 60 revolutions per minute), 3 the stopping distance shall be 4... gear development greater than 6.67 m (21.9 ft) in the bicycle's highest gear ratio. Gear development is... crank shall be not more than 60° with the crank held against each position under a torque of no...

  18. Direct Measurement of the Isomerization Barrier of the Isolated Retinal Chromophore

    Science.gov (United States)

    2015-11-03

    currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 03/11/2015 2. REPORT TYPE...photoisomerization of retinal 24 Acknowledgements Bar-Ilan University: Dr. Yoni Toker Lihi Musbat Funding: NSWC Crane NISE / 219 Indiana University

  19. A Guide for Measuring, Analyzing, and Evaluating Accelerations Recorded During Seakeeping Trials of High-Speed Craft

    Science.gov (United States)

    2016-01-01

    failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE...Headings ......................................................16 Figure 15. Example Comparison of RSI Values With and Without Ride Control ...Naval Innovative Science and Engineering ( NISE ) Section 219 research and development program. ACKNOWLEDGEMENTS The authors would like to thank Dr

  20. Performance of 3 Rapid Tests for Discrimination Between HIV-1 and HIV-2 in Guinea-Bissau, West Africa

    DEFF Research Database (Denmark)

    Hønge, Bo Langhoff; Bjarnason Obinah, Magnús Pétur; Jespersen, Sanne;

    2014-01-01

    rapid tests for discrimination between HIV-1, HIV-2, and dual infections among 219 patients from Guinea-Bissau by comparing with the gold standard (INNO-LIA). Genie III HIV-1/HIV-2 was the best performer with regard to discriminatory capacity (agreement 91.8%), followed by Immunoflow HIV1-HIV2...

  1. Resources for Increasing Physical Activity in Children and Youth

    Science.gov (United States)

    Ryan, Carol A.; Beighle, Aaron

    2010-01-01

    The number of children and youth who are overweight has reached epidemic proportions in the United States. According to the 2007-2008 National Health and Nutrition Examination Survey (NHANES) conducted by the Centers for Disease Control and Prevention (CDC), an estimated 17 percent of children and adolescents ages 2-19 years are obese. In…

  2. 78 FR 26069 - Top RX Pharmacy; Decision and Order

    Science.gov (United States)

    2013-05-03

    ... Enforcement Administration Top RX Pharmacy; Decision and Order On November 8, 2012, Chief Administrative Law... ALJ's reasoning suggests that ``inaction'' on the part of a pharmacy's principals in dispensing.../Pharmacy Nos. 219 and 5195, 77 FR 62316, 62317-22 (2012). Order Pursuant to the authority vested in me by...

  3. 78 FR 78275 - Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2014

    Science.gov (United States)

    2013-12-26

    ... Federal Railroad Administration 49 CFR Part 219 Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2014 AGENCY: Federal Railroad Administration (FRA), DOT. ACTION: Notice of determination... therefore determined that the minimum annual random drug testing rate for the period January 1, 2014...

  4. 75 FR 79308 - Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2011

    Science.gov (United States)

    2010-12-20

    ... Federal Railroad Administration 49 CFR Part 219 Alcohol and Drug Testing: Determination of Minimum Random... rail industry random testing positive rates were .037 percent for drugs and .014 percent for alcohol. Because the industry-wide random drug testing positive rate has remained below 1.0 percent for the last...

  5. 77 FR 75896 - Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2013

    Science.gov (United States)

    2012-12-26

    ... Federal Railroad Administration 49 CFR Part 219 Alcohol and Drug Testing: Determination of Minimum Random.... According to data from FRA's Management Information System, the rail industry's random drug testing positive... (Administrator) has therefore determined that the minimum annual random drug testing rate for the period January...

  6. 76 FR 80781 - Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2012

    Science.gov (United States)

    2011-12-27

    ... Federal Railroad Administration 49 CFR Part 219 RIN 2130-AA81 Alcohol and Drug Testing: Determination of... random drug testing ] positive rate has remained below 1.0 percent for the last two years. The Federal Railroad Administrator (Administrator) has therefore determined that the minimum annual random drug testing...

  7. 75 FR 1547 - Alcohol and Drug Testing: Determination of Minimum Random Testing Rates for 2010

    Science.gov (United States)

    2010-01-12

    ... Federal Railroad Administration 49 CFR Part 219 RIN 2130-AA81 Alcohol and Drug Testing: Determination of... percent for drugs and 0.15 percent for alcohol. Because the industry-wide random drug testing positive... (Administrator) has determined that the minimum annual random drug testing rate for the period January 1, 2010...

  8. 75 FR 74127 - In the Matter of the Review of the Designation of Islamic Movement of Uzbekistan (IMU and Other...

    Science.gov (United States)

    2010-11-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE In the Matter of the Review of the Designation of Islamic Movement of Uzbekistan (IMU and Other Aliases) as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality Act, as...

  9. Effect of viscosity on appetite and gastro-intestinal hormones

    NARCIS (Netherlands)

    Zijlstra, N.; Mars, M.; Wijk, de R.A.; Westerterp-Plantenga, M.S.; Holst, J.J.; Graaf, de C.

    2009-01-01

    In previous studies we showed that higher viscosity resulted in lower ad libitum intake and that eating rate is an important factor. In this study we aimed to explore the effect of viscosity on the gastro-intestinal hormones ghrelin, CCK-8 and GLP-1. Thirty-two subjects (22 ± 2 y, BMI 21.9 ± 2.2 kg/

  10. The Effects of Duration and Frequency of Occurrence of Voiceless Fricatives on Listeners' Perceptions of Sound Prolongations

    Science.gov (United States)

    Kawai, Norimune; Healey, E. Charles; Carrell, Thomas D.

    2012-01-01

    The present study examined listeners' identification and rating of words in passages as stuttered when the duration and frequency of occurrence of sound prolongations were manipulated. Thirty-six participants listened to a 219-word passage containing voiceless fricatives digitally increased from their normal durations to 200, 300, and 420 ms.…

  11. Dicty_cDB: CFD757 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LEa0014A23f, mRNA sequence. 74 6e-12 2 AF333116 |AF333116.1 Sterkiella histriomuscorum turgor-like protein g...56 AY883858_1( AY883858 |pid:none) Sterkiella histriomuscorum turgor ... 219 1e-5

  12. Dicty_cDB: AFJ614 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available A sequence. 42 1e-05 3 BG711333 | ( S74728 ) antiquitin=26g turgor protein homolog [human, kidney, Peptide, ...Sterkiella histriomuscorum turgor ... 219 2e-55 BT067707_1( BT067707 |pid:none) Zea mays full-length cDNA cl

  13. Dicty_cDB: VFI240 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 3e-05 3 BG711333 | ( S74728 ) antiquitin=26g turgor protein homolog [human, kidney, Peptide, 511 aa] [Homo s...8 |pid:none) Sterkiella histriomuscorum turgor ... 219 1e-55 AY847462_1( AY847462 |pid:none) Acanthopagrus s

  14. Effects of Welfare Participation on Marriage

    Science.gov (United States)

    Teitler, Julien O.; Reichman, Nancy E.; Nepomnyaschy, Lenna; Garfinkel, Irwin

    2009-01-01

    We investigated the widely held premise that welfare participation causes women to refrain from marriage. Using data from the Fragile Families and Child Wellbeing Study (N = 3,219), we employed an event history approach to study transitions to marriage among mothers who have had a nonmarital birth. We found that welfare participation reduces the…

  15. Panorama of PetroChina Oil and Gas Development in 1996~2000

    Institute of Scientific and Technical Information of China (English)

    Jiang Sixiong

    2001-01-01

    @@ As of the end of 2000,PetroChina found 293 oil fields in total across China with the proven oil in place being 14.35 billion tons and the recoverable reserves being 4.38 billion tons. A total of 219 oil fields in its affiliated 13oil areas have been put into development.

  16. Internet Integration in High Schools: Patterns, Opportunities, and Barriers.

    Science.gov (United States)

    Thomas, Ruth; Adams, Marilyn; Meghani, Naheed; Smith, Maria

    Internet integration in high schools on a schoolwide scale was examined through case studies of five high schools in inner city, urban, suburban, and rural communities across the United States. A total of 322 teachers, 19 administrators, 19 counselors, 7 technology coordinators, and 3,822 students were surveyed, and 219 staff and students were…

  17. Water Efficient Installations - A New Army Guidance Document

    Science.gov (United States)

    2010-06-01

    Detection and Repair 4. Water Efficient Landscaping 5. Water Efficient Irrigation 6. Toilets and Urinals 7. Faucets and Showerheads 8. Boiler/Steam...lose 8760 to 219,000 gal/year Broken flush valve on toilet can lose 40 gal/hour US Army Corps of Engineers® Engineer Research and Development Center...Amendments ( Compost ) 20 Irrigation Scheduling

  18. What Teens Want to Know: Sexual Health Questions Submitted to a Teen Web Site

    Science.gov (United States)

    Vickberg, Suzanne M. Johnson; Kohn, Julia E.; Franco, Lydia M.; Criniti, Shannon

    2003-01-01

    In 1999 Planned Parenthood[R] Federation of America (PPFA[R]) launched teenwire.com[SM], a Web site for young people. This study was designed to determine teens' reproductive health information needs. Selected for analysis were 1,219 submissions to the Ask the Experts section of the Web site. Each submission was independently coded by three of the…

  19. The Validity of the GMAT for the Prediction of Grades in Doctoral Study in Business and Management: An Empirical Bayes Approach.

    Science.gov (United States)

    Zwick, Rebecca

    1993-01-01

    A validity study with 5,219 students examined the degree to which Graduate Management Admission Test (GMAT) scores and undergraduate grade point average (GPA) could predict first-year average and final GPA in doctoral programs in business. The usefulness of the predictions derived from the empirical Bayes regression models is discussed. (SLD)

  20. 48 CFR 719.271-1 - General.

    Science.gov (United States)

    2010-10-01

    ... 719.271-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271-1 General. The purpose of this section is to prescribe responsibilities and procedures for carrying out the small business program policy set forth in 219.270, and...

  1. Canine Autoanticoagulation during Extracorporeal Perfusion.

    Science.gov (United States)

    1979-12-19

    Chronolog, Havertown, PA). Aggregating agents, adenosine diphosphate (ADP) (Si.ma Chemical Co., St. Louis, 14) and topical bovine thrombin (Parke-Davis...time with kaolin ; a simple screening test for first stage plasma clotting factor deficiencies. Amer. J. Clin. Pathol. 36: 212-219, 1961. 35. Quick, A

  2. 75 FR 69733 - California Disaster #CA-00161

    Science.gov (United States)

    2010-11-15

    ... [Federal Register Volume 75, Number 219 (Monday, November 15, 2010)] [Notices] [Page 69733] [FR Doc No: 2010-28587] SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12373 and 12374] California Disaster CA-00161 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice...

  3. What Proportion of Preschool-Aged Children Consume Sweetened Beverages?

    Science.gov (United States)

    Nickelson, Jen; Lawrence, Jeannine C.; Parton, Jason M.; Knowlden, Adam P.; McDermott, Robert J.

    2014-01-01

    Background: Obesity affects nearly 17% of US children and youth 2-19?years old and 10% of infants and toddlers under the age of 2?years. One strategy for addressing obesity is to discourage sugar-sweetened beverage (SSB) consumption. Compared with their older school-aged counterparts, children =5?years depend largely on parents for the purchase…

  4. A Cross-Cultural Study of Children's Perceptions of Selected Religious Concepts.

    Science.gov (United States)

    Nazar, Fatima; Kouzekanani, Kamiar

    2003-01-01

    A survey of 219 children from a kindergarten in the United States and a Kuwaiti kindergarten and Indian private preschool in Kuwait examined children's perceptions of God, death, and the afterlife. The common responses of the children suggest that although different views of Islam, Christianity, and Hinduism may appear contradictory, they are all…

  5. 77 FR 71163 - Federal Motor Vehicle Safety Standards; Windshield Zone Intrusion

    Science.gov (United States)

    2012-11-29

    ... National Highway Traffic Safety Administration 49 CFR Part 571 RIN 2127-AK13 Federal Motor Vehicle Safety... rulemaking proposal to rescind Federal Motor Vehicle Safety Standard (FMVSS) No. 219, ``Windshield zone... members included: BMW Group, Chrysler LLC, Ford Motor Company, General Motors, Mazda, Mercedes-Benz...

  6. PHENOBARBITAL FOR THE PREVENTION OF INTRACRANIAL DAMAGE IN CHINESE NEONATES WITH SEVERE ASPHYXIA

    Institute of Scientific and Technical Information of China (English)

    陈惠金; 吴圣楣; 黄萍; 孙建华; 陈冠仪; 储淞雯

    2000-01-01

    R6sumeobjectiIPOurevaiuerlletprdventifduphenobarbitalsurleslesionsintracrdniennesasPhyxiquesainsiquelemalePilePtiquedesnouveau'nes.MdthodesUnessatcontr6leaeteportesur6onouveau-nesgravementasPhyxies.Ladose-chargedephenobarbitals,estfaitesur3Onouveau-ndsavantlngemOyende5.6heures.R/suItatsPasdedJfdrencesignilicativen'aetetrouveeconcernantpoidscorPorel,dgegestationel,scoresAPgaretsexneonataldesdeuxgrouPesdesnouveau-nes.LaconcentrationseriquedephdnobarbitalaetdenmOyenne21.9Pg/ml4joursaPrbslanaissance.Lesimagesso...

  7. NASA/DoD Aerospace Knowledge Diffusion Research Project. Paper Twenty Nine. The U.S. Government Technical Report and the Transfer of Federally Funded Aerospace R&D

    Science.gov (United States)

    1993-08-01

    Knowledge Diffusion Research Project," Government Information Quarterly 8, no. 2 (1991):219-33. 7. Steven Ballard, et al.. Improving the Transfer and...Literature: Research Needs and Issues," Government Information Quarterly 5, no. I (1988):27-44. 15. Steven Ballard, et al., Innovation Through Technical

  8. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 16. A Comparison of the Technical Communications Practices of Russian and U.S. Aerospace Engineers and Scientists

    Science.gov (United States)

    1993-01-01

    Barclay. "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2 (1991): 219-233. 29 APPENDIX A NASA/DoD...M. Kennedy; and Rebecca 0. Barclay. The NASA/DoD Aerospace Knowledge Diffusion Research Project. Reprinted from Government Information Quarterly , Volume

  9. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 14. Engineering Work and Information Use in Aerospace: Results of a Telephone Survey

    Science.gov (United States)

    1992-10-01

    Kennedy; and Rebecca 0. Barclay. "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8.2 (1991): 219-233...Rebecca 0. Barclay. The NASA/DoD Aerospace Knowledge Diffusion Research Project. Reprinted from Government Information Quarterly , Volume 8, "’). 2

  10. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 19. The U. S. Government Technical Report and the Transfer of Federally Funded Aerospace R&D: An Analysis of Five Studies

    Science.gov (United States)

    1994-01-01

    Merrill. D. W. Stevenson 1976 McClure, C. R. "The Federal Technical Report Literature: Research Needs and 1988 Issues." Government Information Quarterly 5...T. E., "The NASA/DoD Aerospace Knowledge Diffusion Research J. M. Kennedy, and Project." Government Information Quarterly 8(2): 219-233. R. 0

  11. A Comparison of the Technical Communications Practices of Dutch U.S. Aerospace Engineers and Scientists. Number 17

    Science.gov (United States)

    1993-07-01

    T. E.; J. M. Kennedy; and R. 0. Barclay. "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2 (1991...Barclay. The NASA/DoD Aerospace Knowledge Diffusion Research Project. Reprinted from Government Information Quarterly , Volume 8, No. 2 (1991): 219

  12. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 23. U.S. Academic Librarians and Technical Information Specialists as Information Intermediaries: Results of the Phase 3 Study

    Science.gov (United States)

    1994-03-01

    Issues." Government Information Quarterly . 5(1): 27-44. McGowan, R. P. and "Strategies for Information Management: The Administrator’s S. Loveless...Kennedy, and Project." Government Information Quarterly 8(2): 219-233. R. 0. Barclay 1991 Pinelli, T. E., "Aerospace Knowledge Diffusion Research

  13. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 20. The Use of Selected Information Products and Services by U.S. Aerospace Engineers and Scientists: Results of Two Surveys.

    Science.gov (United States)

    1994-02-01

    Stevenson 1976 McClure, C. R. "The Federal Technical Report Literature: Research Needs and 1988 Issues." Government Information Quarterly 5(1): 27-44...Pinelli, T. E., "The NASA/DoD Aerospace Knowledge Diffusion Research J. M. Kennedy, and Project." Government Information Quarterly 8(2): 219-233. R. 0

  14. Sociocultural Influences on Body Image Concerns of Young Chinese Males

    Science.gov (United States)

    Jackson, Todd; Chen, Hong

    2008-01-01

    This research assessed the extent to which sociocultural factors implicated in explanations of weight dissatisfaction among young Western females extend to sources of body image concern in emerging adult and adolescent males from the People's Republic of China. In Study 1, 219 Mainland Chinese male university students completed measures of stature…

  15. A Cross-Cultural Analysis of Interpersonal Needs.

    Science.gov (United States)

    Cambra, Ronald E.; Klopf, Donald W.

    The Fundamental Interpersonal Relations Orientation--Behavior (FIRO-B) was administered to 504 Japanese, 219 Australian, 73 Korean, and 397 United States college students to assess interpersonal needs in the four cultures. The FIRO-B provides ratings for inclusion, control, and affection needs on an "expressed" dimension to indicate the…

  16. Effects of Immigration on Selected Health Risk Behaviors of Black College Students

    Science.gov (United States)

    Kenya, Sonjia; Brodsky, Mitchell; Divale, William; Allegrante, John P.; Fullilove, Robert E.

    2003-01-01

    The authors administered the National College Health Risk Behavior Survey to 1,219 college students who were attending a historically Black college located in New York City. They assessed the US-born Black students and Black students who emigrated to the United States for differences in risky sexual behaviors, risky dietary behaviors, and physical…

  17. File list: His.Liv.10.AllAg.Liver [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Liv.10.AllAg.Liver mm9 Histone Liver Liver SRX591723,SRX591725,SRX591727,SRX219...0338,SRX100343 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Liv.10.AllAg.Liver.bed ...

  18. InterProScan Result: FY011491 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY011491 FY011491_5_ORF2 014FA900E6EE219A PFAM PF00361 Oxidored_q1 3.7e-16 T IPR001...750 NADH:ubiquinone/plastoquinone oxidoreductase Molecular Function: NADH dehydrogenase (ubiquinone) activit

  19. 48 CFR 970.1907-1 - Subcontracting plan requirements.

    Science.gov (United States)

    2010-10-01

    ... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Small, Small Disadvantaged and Women-Owned Small Business Concerns 970.1907-1 Subcontracting plan requirements. Pursuant to the clause at 48 CFR 52.219-9, Small Business Subcontracting Plan, which is required for all management and...

  20. 77 FR 14303 - Federal Acquisition Regulation; Women-Owned Small Business (WOSB) Program

    Science.gov (United States)

    2012-03-09

    ... Economically Disadvantaged Women-Owned Small Business (EDWOSB) Concerns (APR 2012) (15 U.S.C. 637(m)).'' 4. On...: ``(25) 52.219-30, Notice of Set-Aside for Women-Owned Small Business (WOSB) Concerns Eligible Under the... Business Concerns Eligible Under the Women-Owned Small Business Program (APR 2012)'' BILLING CODE......

  1. 78 FR 37676 - Federal Acquisition Regulation; System for Award Management Name Change, Phase 1 Implementation

    Science.gov (United States)

    2013-06-21

    ...)). ---- (24) 52.219-29, Notice of Set-Aside for Economically Disadvantaged Women-Owned Small Business (EDWOSB..., or small, HUBZone, small disadvantaged, and women-owned small business trade associations). A firm... veteran-owned small, HUBZone small, small disadvantaged, and women-owned small......

  2. 76 FR 68032 - Federal Acquisition Regulation; Set-Asides for Small Business

    Science.gov (United States)

    2011-11-02

    ... the clause 52.219-29, Notice of Set-Aside for Economically Disadvantaged Women-owned Small Business... disadvantaged women-owned small business (EDWOSB) concerns under 19.1505(b). This includes multiple-award... Small Business Concerns Eligible Under the Women-Owned Small Business Program, in solicitations...

  3. Advanced Languages for Systems Software

    Science.gov (United States)

    1994-01-01

    these are too numerous to list here. Edoardo Biagioni . Post-doctoral researcher. System networking and kernel design and imple- mentation. Kenneth Cline...John Backus, John H. Williams, and Edward L. Wimmers. The programming language FL. In Turner [131], pages 219-247. [12] Edoardo Biagioni , Nicholas

  4. AcEST: DK948146 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ne and TPR repeat-containing pr... 30 8.2 sp|A2R3F3|SHE9_ASPNC Sensitive to high expression protein 9 homo.....QLQPEQGAAYVTYGQTLARNGS 710 Query: 221 R 219 R Sbjct: 711 R 711 >sp|A2R3F3|SHE9_ASPNC Sensitive

  5. File list: Oth.Dig.50.VSV-G.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Dig.50.VSV-G.AllCell hg19 TFs and others VSV-G Digestive tract SRX961218,SRX961...219 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Dig.50.VSV-G.AllCell.bed ...

  6. File list: Oth.Dig.20.VSV-G.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Dig.20.VSV-G.AllCell hg19 TFs and others VSV-G Digestive tract SRX961218,SRX961...219 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Dig.20.VSV-G.AllCell.bed ...

  7. File list: Oth.Dig.05.VSV-G.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Dig.05.VSV-G.AllCell hg19 TFs and others VSV-G Digestive tract SRX961218,SRX961...219 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Dig.05.VSV-G.AllCell.bed ...

  8. File list: Oth.Dig.10.VSV-G.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Dig.10.VSV-G.AllCell hg19 TFs and others VSV-G Digestive tract SRX961218,SRX961...219 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Dig.10.VSV-G.AllCell.bed ...

  9. File list: His.Bld.50.AllAg.Th17 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Bld.50.AllAg.Th17 mm9 Histone Blood Th17 SRX187222,SRX187221,SRX187220,SRX18722...219,SRX003814 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Bld.50.AllAg.Th17.bed ...

  10. Development and Validation of an HPLC Method for the ...

    African Journals Online (AJOL)

    ... injection volume 10 μl and quantification by UV detection at λ max 219 nm. The method provided a short analysis time: PGS, tR = 3.07 min; SB, tR = 8.09 min ... With regard to percent organic modifier (methanol) a significant difference was ...

  11. Denying Al Qaeda Safe Haven in a Weak State: An Analysis of U.S. Strategy in Yemen

    Science.gov (United States)

    2010-12-01

    Jihadists including Umar Forouk Abdulmutallab, and John Walker Lindh . 141 Although suspected of being a weapons storage facility in addition to a...Westview Press, 1996), 219. 141 John Walker Lindh was an American captured in Afghanistan fighting alongside al Qaeda forces. Steven Erlanger, “At

  12. AcEST: DK947974 [AcEST

    Lifescience Database Archive (English)

    Full Text Available UCC_BRUSI Succinyl-CoA ligase [ADP-forming] subunit b... 31 5.5 sp|A5VSQ3|SUCC_BRUO2 Succinyl-CoA ligase [AD...L Sbjct: 219 VRVLDAKVSFDNNALFRHPDIVELRDL 245 >sp|A5VSQ3|SUCC_BRUO2 Succinyl-CoA ligase [ADP-forming] subunit

  13. AcEST: DK948070 [AcEST

    Lifescience Database Archive (English)

    Full Text Available CC_BRUSI Succinyl-CoA ligase [ADP-forming] subunit b... 31 5.5 sp|A5VSQ3|SUCC_BRUO2 Succinyl-CoA ligase [ADP... Sbjct: 219 VRVLDAKVSFDNNALFRHPDIVELRDL 245 >sp|A5VSQ3|SUCC_BRUO2 Succinyl-CoA ligase [ADP-forming] subunit

  14. Advanced Bridge Capacity and Structural Integrity Assessment Methodology

    Science.gov (United States)

    2013-03-01

    Wickline, Cousins and Seda -Sanabria 2003, ACI Committee 435 1966). In this project, the extent of cracking along the beam was considered by looking at...Shear." ACI Journal, March-April 1986: 219-231. ERDC/CERL TR-13-3 104 Wickline, Joseph E., Thomas E. Cousins, and Yazmin Seda -Sanabria. "ERDC/GSL TR

  15. Plan for Engineering and Design. Des Moines Recreational River and Greenbelt, Des Moines River, Iowa.

    Science.gov (United States)

    1986-03-01

    Geographic information will be stored in a computerized database. Regional clima - tology and local hydrology will be presented in the GDM to describe...HEALTH AND HUMAN " 219 POST ODFItS BUILDING SlieVeisl AMES. IOwA 50010 DIPAITMINT Of LABOR PHoNoE 159I) 232-9221 DPARTMtEi OF TRANISFOBlTATION October 11

  16. 77 FR 44307 - In the Matter of the Review of the Designation of the Islamic Resistance Movement (Hamas and...

    Science.gov (United States)

    2012-07-27

    ... terrorist organization have not changed in such a manner as to warrant revocation of the designation and... Matter of the Review of the Designation of the Islamic Resistance Movement (Hamas and Other Aliases) As a Foreign Terrorist Organization pursuant to Section 219 of the Immigration and Nationality Act, as Amended...

  17. Photodynamic Therapy

    Science.gov (United States)

    ... Oncol . 2004;5:497-508. Hopper C. Photodynamic therapy: a clinical reality in the treatment of cancer. Lancet Oncol . 2000;1:212-219. Huang Z. A review of progress in clinical photodynamic therapy. Technol Cancer Res Treat . 2005;4:283-293. ...

  18. Models in Insurance: Paradigms, Puzzles, Communications and Revolutions.

    Science.gov (United States)

    1980-06-01

    Models in Light of Futurism," 229-242. [80.22] A. Martinez, "Interpretaci6n del Fen6mino Actuarial mediante un Proceso Estocastico Evolutivo de Variables... Teoria della Credibilit&," Giornale dell’ Istituto degli Attuari, 27, 219-231 (1964). (D51 N. De Pril, "The Efficiency of a Bonus-Malus System," AB, 10

  19. Children Dwelling in the Absence of Home

    African Journals Online (AJOL)

    denise

    ... “at home, the poor, the homeless, the disenfranchised, and the young are .... Alberta Journal of Education Research, 57(2), 219-232. Fantino, A. ... Trying to teach in a season of great untruth: Globalization, empire and the crisis of pedagogy.

  20. Department of Labor Semiannual Regulatory Agenda

    Science.gov (United States)

    2010-04-26

    ... Fair Labor Standards Act 1235-AA04 ] Wage and Hour Division--Final Rule Stage Regulation Sequence Title Identifier Number Number 219 Amendments to the Fair Labor Standards Act 1235-AA00 220 Child Labor Regulations... Sequence Title Identifier Number Number 221 Application of the Fair Labor Standards Act to Domestic Service...