WorldWideScience

Sample records for actinium 217

  1. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-08-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1- ligands (3.2+/-1.1) than AmIII (0.8+/-0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour.

  2. Separation of Actinium 227 from the uranium minerals

    International Nuclear Information System (INIS)

    The purpose of this work was to separate Actinium 227, whose content is 18%, from the mineral carnotite found in Gomez Chihuahua mountain range in Mexico. The mineral before processing is is pre-concentrated and passed, first through anionic exchange resins, later the eluate obtained is passed through cationic resins. The resins were 20-50 MESH QOWEX and 100-200 MESH 50 X 8-20 in some cased 200-400 MESH AG 50W-X8, 1X8 in other cases. The eluates from the ionic exchange were electrodeposited on stainless steel polished disc cathode and platinum electrode as anode; under a current ODF 10mA for 2.5 to 5 hours and of 100mA for .5 of an hour. it was possible to identify the Actinium 227 by means of its descendents, TH-227 and RA-223, through alpha spectroscopy. Due to the radiochemical purity which the electro deposits were obtained the Actinium 227 was low and was not quantitatively determined. A large majority of the members of the natural radioactive series 3 were identified and even alpha energies reported in the literature with very low percentages of non-identified emissions were observed. We conclude that a more precise study is needed concerning ionic exchange and electrodeposit to obtain an Actinium 227 of radiochemical purity. (Author)

  3. Spectroscopic and computational investigation of actinium coordination chemistry

    Science.gov (United States)

    Ferrier, Maryline G.; Batista, Enrique R.; Berg, John M.; Birnbaum, Eva R.; Cross, Justin N.; Engle, Jonathan W.; La Pierre, Henry S.; Kozimor, Stosh A.; Lezama Pacheco, Juan S.; Stein, Benjamin W.; Stieber, S. Chantal E.; Wilson, Justin J.

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, AcIII reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac–Cl and Ac–OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between AcIII and AmIII in HCl solutions indicate AcIII coordinates more inner-sphere Cl1– ligands (3.2±1.1) than AmIII (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique AcIII chemical behaviour. PMID:27531582

  4. Discovery of the actinium, thorium, protactinium, and uranium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, 31 actinium, 31 thorium, 28 protactinium, and 23 uranium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  5. Spectroscopic and computational investigation of actinium coordination chemistry.

    Science.gov (United States)

    Ferrier, Maryline G; Batista, Enrique R; Berg, John M; Birnbaum, Eva R; Cross, Justin N; Engle, Jonathan W; La Pierre, Henry S; Kozimor, Stosh A; Lezama Pacheco, Juan S; Stein, Benjamin W; Stieber, S Chantal E; Wilson, Justin J

    2016-01-01

    Actinium-225 is a promising isotope for targeted-α therapy. Unfortunately, progress in developing chelators for medicinal applications has been hindered by a limited understanding of actinium chemistry. This knowledge gap is primarily associated with handling actinium, as it is highly radioactive and in short supply. Hence, Ac(III) reactivity is often inferred from the lanthanides and minor actinides (that is, Am, Cm), with limited success. Here we overcome these challenges and characterize actinium in HCl solutions using X-ray absorption spectroscopy and molecular dynamics density functional theory. The Ac-Cl and Ac-OH2O distances are measured to be 2.95(3) and 2.59(3) Å, respectively. The X-ray absorption spectroscopy comparisons between Ac(III) and Am(III) in HCl solutions indicate Ac(III) coordinates more inner-sphere Cl(1-) ligands (3.2±1.1) than Am(III) (0.8±0.3). These results imply diverse reactivity for the +3 actinides and highlight the unexpected and unique Ac(III) chemical behaviour. PMID:27531582

  6. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    International Nuclear Information System (INIS)

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces ∼100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 GeV protons

  7. Production of Actinium-225 via High Energy Proton Induced Spallation of Thorium-232

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, James T.; Nolen, Jerry; Vandergrift, George; Gomes, Itacil; Kroc, Tom; Horwitz, Phil; McAlister, Dan; Bowers, Del; Sullivan, Vivian; Greene, John

    2011-12-30

    The science of cancer research is currently expanding its use of alpha particle emitting radioisotopes. Coupled with the discovery and proliferation of molecular species that seek out and attach to tumors, new therapy and diagnostics are being developed to enhance the treatment of cancer and other diseases. This latest technology is commonly referred to as Alpha Immunotherapy (AIT). Actinium-225/Bismuth-213 is a parent/daughter alpha-emitting radioisotope pair that is highly sought after because of the potential for treating numerous diseases and its ability to be chemically compatible with many known and widely used carrier molecules (such as monoclonal antibodies and proteins/peptides). Unfortunately, the worldwide supply of actinium-225 is limited to about 1,000mCi annually and most of that is currently spoken for, thus limiting the ability of this radioisotope pair to enter into research and subsequently clinical trials. The route proposed herein utilizes high energy protons to produce actinium-225 via spallation of a thorium-232 target. As part of previous R and D efforts carried out at Argonne National Laboratory recently in support of the proposed US FRIB facility, it was shown that a very effective production mechanism for actinium-225 is spallation of thorium-232 by high energy proton beams. The base-line simulation for the production rate of actinium-225 by this reaction mechanism is 8E12 atoms per second at 200 MeV proton beam energy with 50 g/cm2 thorium target and 100 kW beam power. An irradiation of one actinium-225 half-life (10 days) produces {approx}100 Ci of actinium-225. For a given beam current the reaction cross section increases slightly with energy to about 400 MeV and then decreases slightly for beam energies in the several GeV regime. The object of this effort is to refine the simulations at proton beam energies of 400 MeV and above up to about 8 GeV. Once completed, the simulations will be experimentally verified using 400 MeV and 8 Ge

  8. 22 CFR 217.45 - Housing.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Housing. 217.45 Section 217.45 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Postsecondary Education § 217.45 Housing. (a) Housing provided by the recipient. A recipient that provides housing to its nonhandicapped students shall...

  9. 46 CFR 169.217 - Posting.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Posting. 169.217 Section 169.217 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS SAILING SCHOOL VESSELS Inspection and Certification Certificate of Inspection § 169.217 Posting. The certificate of inspection must be framed...

  10. 48 CFR 217.7601 - Provisioning.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Provisioning. 217.7601... Provisioning Requirements 217.7601 Provisioning. (a) Follow the procedures at PGI 217.7601 for contracts with provisioning requirements. (b) For technical requirements of provisioning, see DoD 4140.1-R, DoD Supply...

  11. 20 CFR 405.217 - Subpoenas.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Subpoenas. 405.217 Section 405.217 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Review of Initial Determinations by a Federal Reviewing Official § 405.217 Subpoenas. (a) When it is reasonably necessary for the...

  12. 47 CFR 97.217 - Telemetry.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Telemetry. 97.217 Section 97.217 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES AMATEUR RADIO SERVICE Special Operations § 97.217 Telemetry. Telemetry transmitted by an amateur station on or within...

  13. 49 CFR 238.217 - Side structure.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Side structure. 238.217 Section 238.217 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Equipment § 238.217 Side structure. Each passenger car shall comply with the following: (a) Side posts...

  14. 29 CFR 780.217 - Forestry activities.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Forestry activities. 780.217 Section 780.217 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL... as It Relates to Specific Situations Hatchery Operations § 780.217 Forestry activities. Operations...

  15. 22 CFR 217.23 - New construction.

    Science.gov (United States)

    2010-04-01

    ... Uniform Federal Accessibility Standards (USAF) (appendix A to 41 CFR subpart 101-19.6) shall be deemed to... 22 Foreign Relations 1 2010-04-01 2010-04-01 false New construction. 217.23 Section 217.23 Foreign... ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Accessibility § 217.23 New construction. (a) Design...

  16. 76 FR 8620 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2011-02-15

    ...We are superseding an existing airworthiness directive (AD) for Pratt & Whitney (PW) JT8D-209, -217, -217A, -217C, and -219 turbofan engines. That AD currently requires revisions to the engine manufacturer's time limits section (TLS) to include enhanced inspection of selected critical life-limited parts at each piece-part opportunity. This new AD modifies the TLS of the manufacturer's engine......

  17. Dicty_cDB: SSI217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SS (Link to library) SSI217 (Link to dictyBase) - - - Contig-U15348-1 SSI217Z (Link... to Original site) - - SSI217Z 662 - - - - Show SSI217 Library SS (Link to library) Clone ID SSI217 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SS/SSI2-A/SSI217Q.Seq.d/ Representative seq. ID SSI21...7Z (Link to Original site) Representative DNA sequence >SSI217 (SSI217Q) /CSM/SS/SSI2-A/SSI217Q.Seq.d/ XXXXX...Frames) Frame A: ---itlepilwplssivililqrn*lisygimgfqnknfscqlmvgi*lprspttillts ivisln*pfqqlkilqeyqcnl**pmmvii

  18. 22 CFR 217.44 - Academic adjustments.

    Science.gov (United States)

    2010-04-01

    ... PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Postsecondary Education § 217.44 Academic... recipient's education program or activity. (c) Course examinations. In its course examinations or...

  19. Analysis of the gamma spectra of the uranium, actinium, and thorium decay series

    International Nuclear Information System (INIS)

    This report describes the identification of radionuclides in the uranium, actinium, and thorium series by analysis of gamma spectra in the energy range of 40 to 1400 keV. Energies and absolute efficiencies for each gamma line were measured by means of a high-resolution germanium detector and compared with those in the literature. A gamma spectroscopy method, which utilizes an on-line computer for deconvolution of spectra, search and identification of each line, and estimation of activity for each radionuclide, was used to analyze soil and uranium tailings, and ore

  20. 48 CFR 217.204 - Contracts.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contracts. 217.204 Section... DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Options 217.204 Contracts. (e)(i) Notwithstanding FAR 17.204(e), the ordering period of a task order or delivery order...

  1. 25 CFR 217.5 - Management decisions.

    Science.gov (United States)

    2010-04-01

    ... Management decisions. In arriving at management decisions concerning the assets, the business committee shall... 25 Indians 1 2010-04-01 2010-04-01 false Management decisions. 217.5 Section 217.5 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS MANAGEMENT OF TRIBAL ASSETS OF...

  2. 14 CFR 145.217 - Contract maintenance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Contract maintenance. 145.217 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.217 Contract maintenance. (a) A certificated repair station may contract a maintenance function pertaining to an article to...

  3. 33 CFR 117.217 - Norwalk River.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Norwalk River. 117.217 Section... DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Connecticut § 117.217 Norwalk River. (a) The draw of.... to 12 p.m., on the first Saturday in December, to facilitate the running of the annual Norwalk...

  4. 40 CFR 86.217-94 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false 86.217-94 Section 86.217-94 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF... Year Gasoline-Fueled New Light-Duty Vehicles, New Light-Duty Trucks and New Medium-Duty...

  5. 27 CFR 24.217 - Vinegar stock.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Vinegar stock. 24.217... OF THE TREASURY LIQUORS WINE Production of Other Than Standard Wine § 24.217 Vinegar stock. Vinegar stock may be produced on bonded wine premises with the addition of any quantity of water desired to...

  6. 33 CFR 136.217 - Compensation allowable.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Compensation allowable. 136.217...) MARINE POLLUTION FINANCIAL RESPONSIBILITY AND COMPENSATION OIL SPILL LIABILITY TRUST FUND; CLAIMS PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.217...

  7. Dicty_cDB: CFD217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF (Link to library) CFD217 (Link to dictyBase) - - - - CFD217P (Link to Original site) CFD217F 882 CFD...217Z 869 CFD217P 1751 - - Show CFD217 Library CF (Link to library) Clone ID CFD217 (Link... to dictyBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig - Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CF/CFD...2-A/CFD217Q.Seq.d/ Representative seq. ID CFD217P (Link to... Original site) Representative DNA sequence >CFD217 (CFD217Q) /CSM/CF/CFD2-A/CFD217Q.Seq.d/ TTTACATATTAATTAA

  8. 48 CFR 217.504 - Ordering procedures.

    Science.gov (United States)

    2010-10-01

    ... Acquisitions Under the Economy Act 217.504 Ordering procedures. (a) When the requesting agency is within DoD, a... obtained from the requesting agency and placed in the contract file for the Economy Act order....

  9. 48 CFR 217.7802 - Policy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy. 217.7802 Section... Issued by a Non-DoD Agency 217.7802 Policy. (a) A DoD acquisition official may place an order, make a... threshold through a non-DoD agency in any fiscal year only if the head of the non-DoD agency has...

  10. 48 CFR 252.217-7004 - Job orders and compensation.

    Science.gov (United States)

    2010-10-01

    ... compensation. 252.217-7004 Section 252.217-7004 Federal Acquisition Regulations System DEFENSE ACQUISITION... of Provisions And Clauses 252.217-7004 Job orders and compensation. As prescribed in 217.7104(a), use the following clause: JOB ORDERS AND COMPENSATION (MAY 2006) (a) The Contracting Officer shall...

  11. 14 CFR 217.10 - Instructions.

    Science.gov (United States)

    2010-01-01

    ... Section 217.10 of 14 CFR Part 217—Instructions to Foreign Air Carriers for Reporting Traffic Data on Form... records: 1 2 3 4 5 6 7 8 9 10 11 Sample No. 1 “CCC” 8701 “JFK” “LHR” “F” 8161 29 59 69 79 89 Sample No. 2 “CCC” 8701 “JFK” “LHR” “F” 6901 299 599 0 0 0 Sample No. 3 “CCC” 8701 “JFK” “LHR” “G” 7102 299 0 599...

  12. 30 CFR 217.200 - Audits.

    Science.gov (United States)

    2010-07-01

    ... copies of audit reports that express opinions on such compliance to the Associate Director for Minerals... INSPECTIONS Coal § 217.200 Audits. An audit of the accounts and books of operators/lessees for the purpose of determining compliance with Federal lease terms relating to Federal royalties may be required annually or...

  13. 7 CFR 1.217 - Witness fees and travel expenses.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Witness fees and travel expenses. 1.217 Section 1.217... Witnesses in Judicial or Administrative Proceedings § 1.217 Witness fees and travel expenses. (a) Any... produce official documents on behalf of the United States is entitled to travel expenses in...

  14. 48 CFR 252.217-7015 - Safety and health.

    Science.gov (United States)

    2010-10-01

    ... U.S.C. 651, et seq.); (b) The Safety and Health Regulations for Ship Repairing (29 CFR part 1915... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Safety and health. 252.217... Clauses 252.217-7015 Safety and health. As prescribed in 217.7104(a), use the following clause: Safety...

  15. 48 CFR 217.173 - Multiyear contracts for weapon systems.

    Science.gov (United States)

    2010-10-01

    ... weapon systems. 217.173 Section 217.173 Federal Acquisition Regulations System DEFENSE ACQUISITION... Mulityear Contracting 217.173 Multiyear contracts for weapon systems. As authorized by 10 U.S.C. 2306b(h... contract for— (a) A weapon system and associated items, services, and logistics support for a weapon...

  16. Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

    Science.gov (United States)

    Henriksen, Gjermund; Bruland, Oyvind S; Larsen, Roy H

    2004-01-01

    The present study explores the use of alpha-particle-emitting, bone-seeking agents as candidates for targeted radiotherapy. Actinium and thorium 1,4,7,10 tetraazacyclododecane N,N',N'',N''' 1,4,7,10-tetra(methylene) phosphonic acid (DOTMP) and thorium-diethylene triamine N,N',N'' penta(methylene) phosphonic acid (DTMP) were prepared and their biodistribution evaluated in conventional Balb/C mice at four hours after injection. All three bone-seeking agents showed a high uptake in bone and a low uptake in soft tissues. Among the soft tissue organs, only kidney had a relatively high uptake. The femur/kidney ratios for 227Th-DTMP, 228-Ac-DOTMP and 227Th-DOTMP were 14.2, 7.6 and 6.0, respectively. A higher liver uptake of 228Ac-DOTMP was seen than for 227Th-DTMP and 227Th-DOTMP. This suggests that some demetallation of the 228Ac-DOTMP complex had occurred. The results indicate that 225Ac-DOTMP, 227Th-DOTMP and 227Th-DTMP have promising properties as potential therapeutic bone-seeking agents.

  17. Developments towards in-gas-jet laser spectroscopy studies of actinium isotopes at LISOL

    Science.gov (United States)

    Raeder, S.; Bastin, B.; Block, M.; Creemers, P.; Delahaye, P.; Ferrer, R.; Fléchard, X.; Franchoo, S.; Ghys, L.; Gaffney, L. P.; Granados, C.; Heinke, R.; Hijazi, L.; Huyse, M.; Kron, T.; Kudryavtsev, Yu.; Laatiaoui, M.; Lecesne, N.; Luton, F.; Moore, I. D.; Martinez, Y.; Mogilevskiy, E.; Naubereit, P.; Piot, J.; Rothe, S.; Savajols, H.; Sels, S.; Sonnenschein, V.; Traykov, E.; Van Beveren, C.; Van den Bergh, P.; Van Duppen, P.; Wendt, K.; Zadvornaya, A.

    2016-06-01

    To study exotic nuclides at the borders of stability with laser ionization and spectroscopy techniques, highest efficiencies in combination with a high spectral resolution are required. These usually opposing requirements are reconciled by applying the in-gas-laser ionization and spectroscopy (IGLIS) technique in the supersonic gas jet produced by a de Laval nozzle installed at the exit of the stopping gas cell. Carrying out laser ionization in the low-temperature and low density supersonic gas jet eliminates pressure broadening, which will significantly improve the spectral resolution. This article presents the required modifications at the Leuven Isotope Separator On-Line (LISOL) facility that are needed for the first on-line studies of in-gas-jet laser spectroscopy. Different geometries for the gas outlet and extraction ion guides have been tested for their performance regarding the acceptance of laser ionized species as well as for their differential pumping capacities. The specifications and performance of the temporarily installed high repetition rate laser system, including a narrow bandwidth injection-locked Ti:sapphire laser, are discussed and first preliminary results on neutron-deficient actinium isotopes are presented indicating the high capability of this novel technique.

  18. 20 CFR 217.15 - Where to file.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Where to file. 217.15 Section 217.15... ANNUITY OR LUMP SUM Filing An Application § 217.15 Where to file. (a) Applicant in U.S. or Canada. An applicant who lives in the United States or Canada may file an application at any Board office in person...

  19. 7 CFR 800.217 - Equipment that shall be tested.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Equipment that shall be tested. 800.217 Section 800... Supervision, Monitoring, and Equipment Testing § 800.217 Equipment that shall be tested. (a) General. Testing... for which official performance requirements have been established shall be tested for accuracy....

  20. 49 CFR 1544.217 - Law enforcement personnel.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Law enforcement personnel. 1544.217 Section 1544... AND COMMERCIAL OPERATORS Operations § 1544.217 Law enforcement personnel. (a) The following applies to... for law enforcement personnel meeting the qualifications and standards specified in §§ 1542.215...

  1. 42 CFR 2.17 - Undercover agents and informants.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Undercover agents and informants. 2.17 Section 2.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS... agent or informant. (b) Restriction on use of information. No information obtained by an...

  2. 25 CFR 217.6 - Method of casting votes.

    Science.gov (United States)

    2010-04-01

    ... the status quo. At the time they notify the superintendent of the votes cast on an issue, each joint... 25 Indians 1 2010-04-01 2010-04-01 false Method of casting votes. 217.6 Section 217.6 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS MANAGEMENT OF TRIBAL ASSETS...

  3. 48 CFR 217.7103-4 - Emergency work.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Emergency work. 217.7103-4... Repair and Alteration of Vessels 217.7103-4 Emergency work. (a) The contracting officer, without... agreement when— (i) Delay in the performance of necessary repair work would endanger a vessel, its cargo...

  4. 14 CFR 217.4 - Data collected (service classes).

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Data collected (service classes). 217.4 Section 217.4 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS REPORTING TRAFFIC STATISTICS BY FOREIGN AIR CARRIERS IN CIVILIAN SCHEDULED, CHARTER, AND NONSCHEDULED SERVICES §...

  5. 5 CFR 532.217 - Appropriated fund survey jobs.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Appropriated fund survey jobs. 532.217... PREVAILING RATE SYSTEMS Prevailing Rate Determinations § 532.217 Appropriated fund survey jobs. (a) A lead agency shall survey the following required jobs: Job title Job grade Janitor (Light) 1 Janitor (Heavy)...

  6. 20 CFR 217.10 - Application filed after death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Application filed after death. 217.10 Section... APPLICATION FOR ANNUITY OR LUMP SUM Applications § 217.10 Application filed after death. (a) A survivor... expenses dies before applying for the lump-sum death payment under part 234 of this chapter....

  7. 34 CFR 668.217 - Default prevention plans.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Default prevention plans. 668.217 Section 668.217... Default prevention plans. (a) First year. (1) If your cohort default rate is equal to or greater than 30 percent you must establish a default prevention task force that prepares a plan to— (i) Identify...

  8. 30 CFR 217.51 - Lease account reconciliation.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Lease account reconciliation. 217.51 Section... MANAGEMENT AUDITS AND INSPECTIONS Oil and Gas, General § 217.51 Lease account reconciliation. Specific lease account reconciliations shall be performed with priority being given to reconciling those lease...

  9. 30 CFR 217.301 - Lease account reconciliations.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Lease account reconciliations. 217.301 Section... MANAGEMENT AUDITS AND INSPECTIONS Geothermal Resources § 217.301 Lease account reconciliations. Specific lease account reconciliations will be performed with priority being given to reconciling those...

  10. 48 CFR 217.171 - Multiyear contracts for services.

    Science.gov (United States)

    2010-10-01

    ... instructor skills (e.g., training for pilots and aircrew members or foreign language training). (iv) Base... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Multiyear contracts for services. 217.171 Section 217.171 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  11. Groundwater seepage from the Ranger uranium mine tailings dam: radioisotopes of radium, thorium and actinium. Supervising Scientist report 106

    International Nuclear Information System (INIS)

    Monitoring of bores near the Ranger uranium mine tailings dam has revealed deterioration in water quality in several bores since 1983. In a group of bores to the north of the dam, increases have been observed of up to 500 times for sulphate concentrations and of up to 5 times for 226Ra concentrations. Results are presented here of measurements of members of the uranium, thorium and actinium decay series in borewater samples collected between 1985 and 1993. In particular, measurements of all four naturally-occurring radium isotopes have been used in an investigation of the mechanism of radium concentration changes. For the most seepage-affected bores the major findings of the study include: 228Ra/226Ra 223Ra /226Ra and 224Ra/228Ra ratios all increased over the course of the study; barium concentrations show high seasonal variability, being lower in November than May, but strontium concentrations show a steady increase with time. Calculations show that the groundwater is probably saturated with respect to barite but not with respect to celestite or anglesite; sulphide concentrations are low in comparison with sulphate, and are higher in November than in May; and 227Ac concentrations have increased with time, but do not account for the high 223Ra/226Ra ratios. It is concluded on the basis of these observations that increases in Ra isotope concentrations observed in a number of seepage-affected bores arise from increases in salinity leading to desorption of radium from adsorption sites in the vicinity of the bore rather by direct transport of radium from the tailings. Increased salinity is also causing the observed increases in 227Ac and strontium concentrations, while formation of a barite solid phase in the groundwater is causing the removal of some radium from solution. This is the cause of the increasing radium isotope ratios noted above

  12. 8 CFR 217.7 - Electronic data transmission requirement.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Electronic data transmission requirement... VISA WAIVER PROGRAM § 217.7 Electronic data transmission requirement. (a) An alien who applies for... manifest data relative to that alien passenger in accordance with 19 CFR 4.7b or 19 CFR 122.49a....

  13. 49 CFR 1542.217 - Law enforcement personnel.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Law enforcement personnel. 1542.217 Section 1542... Law enforcement personnel. (a) Each airport operator must ensure that law enforcement personnel used... the criminal laws of the State and local jurisdictions in which the airport is located— (1) A...

  14. 7 CFR 2.17 - Under Secretary for Rural Development.

    Science.gov (United States)

    2010-01-01

    ... international organizations throughout the world on subjects related to the development and operation of... Agricultural Product Market Development Grant program (note to 7 U.S.C. 1621). (xxii) Administer the... 7 Agriculture 1 2010-01-01 2010-01-01 false Under Secretary for Rural Development. 2.17 Section...

  15. 5 CFR 179.217 - Non-waiver of rights by payments.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Non-waiver of rights by payments. 179.217 Section 179.217 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Salary Offset § 179.217 Non-waiver of rights by payments. An employee's...

  16. 40 CFR 80.217 - How does a refiner or importer apply for the GPA standards?

    Science.gov (United States)

    2010-07-01

    ... for the GPA standards? 80.217 Section 80.217 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...-in Program § 80.217 How does a refiner or importer apply for the GPA standards? (a) To apply for the GPA standards under § 80.216, a refiner or importer must submit an application in accordance with...

  17. 49 CFR 217.11 - Program of instruction on operating rules; recordkeeping; electronic recordkeeping.

    Science.gov (United States)

    2010-10-01

    ...; recordkeeping; electronic recordkeeping. 217.11 Section 217.11 Transportation Other Regulations Relating to... General § 217.11 Program of instruction on operating rules; recordkeeping; electronic recordkeeping. (a... inspection and copying during normal business hours. This program shall— (1) Describe the means...

  18. Dust Plasma Analogue for Interstellar 217.5 nm Extinction

    Directory of Open Access Journals (Sweden)

    Stefanović, I.

    2008-12-01

    Full Text Available The new ultraviolet (UV extinction measurements of carbonaceous nanoparticles in the range from 140 nm to 260 nm are presented. The plasma polymerized hydrocarbon nanoparticles were already proposed as a new astro analogue, which describe the infrared (IR extinction spectra in an excellent way. We use the same particles to find the possible carrier of the "mysterious" UV 217.5 nm extinction "bump" of interstellar media (ISM.

  19. Proton Polarimeter Calibration between 82 and 217 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Glister, J; Lee, B; Beck, A; Brash, E; Camsonne, A; Choi, S; Dumas, J; Feuerbach, R; Gilman, R; Higinbotham, D W; Jiang, X; Jones, M K; May-Tal Beck, S; McCullough, E; Paolone, M; Piasetzky, E; Roche, J; Rousseau, Y; Sarty, A J; Sawatzky, B; Strauch, S

    2009-07-01

    The proton analyzing power in carbon has been measured for energies of 82 to 217 MeV and proton scattering angles of 5 to 41 degrees. The measurements were carried out using polarized protons from the elastic scattering H(pol. e, pol. p) reaction and the Focal Plane Polarimeter (FPP) in Hall A of Jefferson Lab. A new parameterization of the FPP p-C analyzing power was fit to the data, which is in good agreement with previous parameterizations and provides an extension to lower energies and larger angles. The main conclusions are that all polarimeters to date give consistent measurements of the carbon analyzing power, independently of the details of their construction and that measuring on a larger angular range significantly improves the polarimeter figure of merit at low energies.

  20. 美国军用手册217F以外的可靠性预计方法%Reliability Prediction Methods Except Mil-HDBK 217F

    Institute of Scientific and Technical Information of China (English)

    周雷; 许新芳; 程俊

    2008-01-01

    介绍美国军用手册217F之外的可靠性预计方法-EPILD-97和NPRD-95数据库,PRISM方法以及FIDES方法等,分别讨论其适用条件和失效率模型,全面比较了包括217F在内的各种可靠性预计方法的优劣.

  1. 48 CFR 217.175 - Multiyear contracts for electricity from renewable energy sources.

    Science.gov (United States)

    2010-10-01

    ... electricity from renewable energy sources. 217.175 Section 217.175 Federal Acquisition Regulations System... renewable energy sources. (a) The head of the contracting activity may enter into a contract for a period not to exceed 10 years for the purchase of electricity from sources of renewable energy, as that...

  2. 9 CFR 93.217 - Import permit and declaration for poultry.

    Science.gov (United States)

    2010-01-01

    ... poultry. 93.217 Section 93.217 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY...

  3. 36 CFR 223.217 - Authority to dispose of special forest products.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Authority to dispose of special forest products. 223.217 Section 223.217 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE AND DISPOSAL OF NATIONAL FOREST SYSTEM TIMBER Special Forest Products §...

  4. 20 CFR 217.7 - Claim filed with the Social Security Administration.

    Science.gov (United States)

    2010-04-01

    ... Administration. (a) Claim is for life benefits. An application for life benefits under title II of the Social... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Claim filed with the Social Security Administration. 217.7 Section 217.7 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE...

  5. 22 CFR 217.10 - Effect of state or local law or other requirements and effect of employment opportunities.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Effect of state or local law or other requirements and effect of employment opportunities. 217.10 Section 217.10 Foreign Relations AGENCY FOR... FINANCIAL ASSISTANCE General Provisions § 217.10 Effect of state or local law or other requirements...

  6. 49 CFR 40.217 - Where is other information on the role of STTs and BATs found in this regulation?

    Science.gov (United States)

    2010-10-01

    ... BATs found in this regulation? 40.217 Section 40.217 Transportation Office of the Secretary of... Personnel § 40.217 Where is other information on the role of STTs and BATs found in this regulation? You can find other information on the role and functions of STTs and BATs in the following sections of...

  7. 25 CFR 217.4 - Referral of questions by the joint managers.

    Science.gov (United States)

    2010-04-01

    ... party's proposal, if any, for solution. Such referrals shall be in writing, addressed to the other joint... DISTRIBUTION CORP. § 217.4 Referral of questions by the joint managers. The business committee and the board...

  8. 42 CFR 436.217 - Individuals receiving home and community-based services.

    Science.gov (United States)

    2010-10-01

    ... Children and Aged, Blind, and Disabled Individuals, Including Pregnant Women § 436.217 Individuals... furnished in a hospital, NF, or an ICF/MR; or (2) Subpart H of this subchapter, the group would...

  9. ZNF217 expression correlates with the biological behavior of human ovarian cancer cells

    Institute of Scientific and Technical Information of China (English)

    Lilin Hang; Min Zhang; Fanliang Meng; Mei Zhong; Jing Li 

    2014-01-01

    Objective:The aim of the study was to investigate the correlation of zinc-finger protein 217 (ZNF217) gene ex-pression with the biological behavior of human ovarian cancer HO-8910 cel s. Methods:The expression of ZNF217 in ovarian carcinoma cel lines was detected by RT-PCR and Western blot, respectively. The biological behaviors of the transfectants were investigated by MTT, in vitro Boyden chamber and in vivo invasion assay, respectively. Results:RT-PCR and Western blotting revealed that transfection of ZNF217 into the HO-8910 cel s significantly increased their proliferation along with mark-edly enhanced in vitro and in vivo invasion and metastatic abilities. MTT assay showed that the proliferation ability of pEGFP-N1-ZNF217/HO-8910 cel s was significantly higher than that of pEGFP-N1/HO-8910 cel s and HO-8910 cel s (P<0.001). The Boyden chamber assay showed that the numbers of migrating pEGFP-N1-ZNF217/HO-8910, pEGFP-N1/HO-8910 and HO-8910 cel s were (141.25 ± 13.91) cel s/200 × field, (82.50 ± 11.73) cel s/200 × field and (81.75 ± 12.12) cel s/200 × field, respectively, with a significant dif erence between them (F=29.274, P<0.001). The nude mouse experiment showed that the in vivo tumor formation ability of pEGFP-N1-ZNF217/HO-8910 cel s was significantly higher than that of pEGFP-N1/HO-8910 cel s (P<0.001). Conclusion:Based on these clinical and laboratory observations, we conclude that ZNF217 may contribute to ovarian cancer invasion and metastasis, and associated with worse clinical outcomes. We evaluated ZNF217’s role as a biomarker of ovarian carcinogenesis and tumor progression in patient samples and explored possible molecular mechanisms in promoting tumor growth and invasion.

  10. Level structure of 217Rn and 221Ra investigated in the alpha-decay 225Th → 221Ra → 217Rn

    International Nuclear Information System (INIS)

    The nuclei 221Ra and 217Rn have been investigated in the α-decay chain 225Th → 221Ra → 217Rn through γ-ray and conversion-electron studies. The short-lived 225Th nuclei (T1/2=8 min) were produced in the 226Ra(α, 5n) reaction, and γ-rays and conversion electrons were measured - between the irradiation periods - in coincidence with α-particles. In 221Ra the five lowest levels are interpreted as members of a K=5/2 parity-doublet with ΔEπ=104 keV. These levels, as well as a higher-lying Kπ=3/2+ band, are consistent with an octupole deformation of 221Ra, as expected from theoretical considerations. In 217Rn only three excited levels are observed, with a favoured α-decay to a 5/2+ excited level thus establishing positive parity for the ground state of 221Ra. (orig.)

  11. 30 CFR 250.217 - What solid and liquid wastes and discharges information and cooling water intake information must...

    Science.gov (United States)

    2010-07-01

    ... information and cooling water intake information must accompany the EP? 250.217 Section 250.217 Mineral... What solid and liquid wastes and discharges information and cooling water intake information must accompany the EP? The following solid and liquid wastes and discharges information and cooling water...

  12. Yeast Interacting Proteins Database: YHR114W, YDL217C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available y (0) YDL217C TIM22 Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopi...rey gene name TIM22 Prey description Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic

  13. 20 CFR 217.11 - “Good cause” for delay in filing application.

    Science.gov (United States)

    2010-04-01

    ... RETIREMENT ACT APPLICATION FOR ANNUITY OR LUMP SUM Applications § 217.11 “Good cause” for delay in filing application. (a) An applicant has “good cause” for a delay in the filing of an application for a lump-sum... time limit. (b) An applicant does not have good cause for a delay in filing if he or she was...

  14. CULTIVAR RELEASE-BRS 217 Flora: Early-maturing soybean cultivar

    Directory of Open Access Journals (Sweden)

    Plínio Itamar de Mello de Souza

    2008-01-01

    Full Text Available The soybean (Glycine max L. Merr. cultivar BRS 217 Flora was developed by Embrapa and released forproduction in the states of Goiás, Minas Gerais, Bahia, Mato Grosso and the Distrito Federal, Brazil. It is resistant to stemcanker, frog-eye leaf spot, bacterial pustule, and partially resistant to powdery mildew.

  15. 5 CFR 531.217 - Special conversion rules for certain non-GS employees.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Special conversion rules for certain non... SERVICE REGULATIONS PAY UNDER THE GENERAL SCHEDULE Determining Rate of Basic Pay Setting Pay When Appointment Or Position Changes § 531.217 Special conversion rules for certain non-GS employees. When...

  16. Yeast Interacting Proteins Database: YBR217W, YMR159C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available YBR217W ATG12 Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated...ption Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to fo

  17. Yeast Interacting Proteins Database: YBR217W, YLR423C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available YBR217W ATG12 Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated...scription Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p t

  18. 20 CFR 725.217 - Determination of dependency; surviving divorced spouse.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Determination of dependency; surviving... Benefits) § 725.217 Determination of dependency; surviving divorced spouse. An individual who is the miner's surviving divorced spouse (see § 725.216) shall be determined to have been dependent on the...

  19. Cytogenetic analysis of 217 couples with adverse pregnancy history%217对不良孕产史夫妇细胞遗传学分析

    Institute of Scientific and Technical Information of China (English)

    何淑贞; 蒲育栋; 曹金如; 陈美玲; 苏焕厚; 邓汉钊; 莫丽芳

    2016-01-01

    目的:探讨不良孕产史与外周血染色体核型之间的关系,为遗传咨询提供依据。方法采集2013年1月至2015年11月来我院就诊的217对不良孕产史患者的外周血,分别进行外周血淋巴细胞培养、制做玻片和G显带后核型分析。结果217对不良孕产史夫妇中共发现染色体异常的核型9例,异常染色体核型检出率为2.07%,多态性核型55例,检出率为12.67%。结论染色体异常是造成患者发生不良孕产史的主要原因之一,因此应对存在不良孕产史的夫妇常规开展细胞遗传学检查及适时的遗传咨询。%Objective To investigate the relationship between abnormal pregnancy and peripheral blood karyo-type, and provide the basis for genetic counseling. Methods The peripheral blood of 217 couples with adverse pregnan-cy history were collected in our hospital from January 2013 to November 2015. Then the peripheral blood lymphocytes were cultured, and karyotype analysis of G banding was carried out. Results Among 217 couples, 9 cases were found with abnormal karyotype (with the detection rate of 2.07%), and 55 cases were found with polymorphic karyotype (with the detection rate of 12.67%). Conclusion Chromosomal abnormality is an important reason that leads to adverse preg-nancy history. Therefore, the couples with adverse pregnancy history should receive routine prenatal cytogenetic exami-nation and consultation to prevent birth defects, and improve the quality of the birth service.

  20. 20 CFR 10.217 - Is COP charged if the employee continues to work, but in a different job that pays less?

    Science.gov (United States)

    2010-04-01

    ... job with different duties with no loss in pay, then COP is not chargeable. COP must be paid and the... work, but in a different job that pays less? 10.217 Section 10.217 Employees' Benefits OFFICE OF... § 10.217 Is COP charged if the employee continues to work, but in a different job that pays less?...

  1. The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5.

    Directory of Open Access Journals (Sweden)

    Hui Wang

    Full Text Available Gastric cancer (GC is one of the most common malignancies worldwide. Emerging evidence has shown that aberrant expression of microRNAs (miRNAs plays important roles in cancer progression. However, little is known about the potential role of miR-217 in GC. In this study, we investigated the role of miR-217 on GC cell proliferation and invasion. The expression of miR-217 was down-regulated in GC cells and human GC tissues. Enforced expression of miR-217 inhibited GC cells proliferation and invasion. Moreover, Glypican-5 (GPC5, a new ocncogene, was identified as the potential target of miR-217. In addition, overexpression of miR-217 impaired GPC5-induced promotion of proliferation and invasion in GC cells. In conclusion, these findings revealed that miR-217 functioned as a tumor suppressor and inhibited the proliferation and invasion of GC cells by targeting GPC5, which might consequently serve as a therapeutic target for GC patients.

  2. GATA3-driven expression of miR-503 inhibits prostate cancer progression by repressing ZNF217 expression.

    Science.gov (United States)

    Jiang, Xingkang; Chen, Yue; Du, E; Yang, Kuo; Zhang, Zhihong; Qi, Shiyong; Xu, Yong

    2016-09-01

    Although increasing evidence demonstrated that deregulation of mircoRNA-503 (miRNA-503) contributes to tumorigenesis, little is known about the biological role and intrinsic regulatory mechanisms of miR-503 in prostate cancer (PCa). In present study, we found that miR-503 was significantly downregulated in advanced PCa tissues and cell lines. Downregulation of miR-503 was strongly associated with aggressive clinical-pathological features and poor prognosis in PCa patients. Ectopic expression of miR-503 significantly inhibited tumor cells growth, cell migration and invasion in vitro and in vivo. Mechanistic studies revealed that ZNF217 was a direct target downstream target of miR-503. Knockdown of ZNF217 mimicked the tumor-suppressive effects of miR-503 overexpression on PCa invasion, whereas ZNF217 overexpression attenuated the tumor-suppressive function of miR-503. Subsequently, miR-503 further modulated the activation of ZNF217-downstream epithelial-mesenchymal transition (EMT) genes. Besides, we also found that GATA3 directly increased miR-503 expression and thus decreased ZNF217 expression, indicating the involvement of GATA3/miR-503/ZNF217 signaling in EMT process. Collectively, our results demonstrated that GATA3-driven expression of miR-503 inhibits PCa progression by repressing ZNF217 expression, and also implicated the potential application of miR-503 in PCa therapy. PMID:27267060

  3. Yeast Interacting Proteins Database: YHR171W, YBR217W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available hagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p a...ugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also f...s prey (1) YBR217W ATG12 Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conj

  4. Clinical Analysis of 217 Children with Hearing Loss%217例听力损失儿童临床特点分析

    Institute of Scientific and Technical Information of China (English)

    蔡娟; 邹凌; 陶宣华; 杨馨婷

    2015-01-01

    Objective To investigate the children with hearing loss which didn’t have newborn hearing screening,and dis-cuss their found age and audiological characteristics. Methods From Oct 2009 to Sep 2013,total of 217 children have diagnosed hearing loss. General information of found age were investigated,and then made statistical analysis. Results The average found age for 43 children with bilateral moderate hearing loss was(55. 3 ± 13. 8)months,and the average found age for 52 children with bilateral severe hearing loss was(32. 0 ± 11. 4) months,the average found age for 79 children with bilateral profound hearing loss was(20.2 ±9.8)months. The average found age for 9 children with unilateral severe hearing loss was(96.1 ±7.6)months,The average found age for 34 children with unilateral profound hearing loss was ( 94. 2 ± 8. 1 ) months. Conclusion The unilateral hearing loss and as the hearing loss degree of children went milder,The found age might be later. It is necessary to popularize new-born hearing screening ,while to enhance the parents’ consciousness,thus promoting the early detection, diagnosis and interven-tion for children with hearing impairment.%目的:探讨未经过新生儿听力筛查,由于听力、语言发育落后而就诊,并诊断为听力损失的217例儿童的听力损失程度、特点及首诊年龄。方法对2009年10月至2013年9月到我院就诊的217例儿童,进行听力学诊断评估。结果217例听力损失患儿中,双耳中度43例,平均首诊发现年龄(55.3±13.8)个月,双耳重度52例,平均发现年龄(32.0±11.4)个月,双耳极重度79例,平均发现年龄(20.2±9.8)个月,单耳重度9例,平均发现年龄(96.1±7.6)个月,单耳极重度34例,平均发现年龄(94.2±8.1)个月。结论单耳听力损失及听力损失程度越轻的患儿,其发现年龄越晚。进行新生儿听力筛查能在6个月龄内早期发现听力损失,并及时康复干预

  5. Accretion-ejection connection in the young brown dwarf candidate ISO-Cha1 217

    CERN Document Server

    Whelan, E T; Bacciotti, F; Nisini, B; Bonito, R; Antoniucci, S; Stelzer, B; Biazzo, K; D'Elia, V; Ray, T P

    2014-01-01

    As the number of observed brown dwarf outflows is growing it is important to investigate how these outflows compare to the well studied jets from young stellar objects. A key point of comparison is the relationship between outflow and accretion activity and in particular the ratio between the mass outflow and accretion rates ($\\dot{M}_{out}$/$\\dot{M}_{acc}$). The brown dwarf candidate ISO-ChaI 217 was discovered by our group, as part of a spectro-astrometric study of brown dwarfs, to be driving an asymmetric outflow with the blue-shifted lobe having a position angle of $\\sim$ 20$^{\\circ}$. The aim here is to further investigate the properties of ISO-ChaI 217, the morphology and kinematics of its outflow, and to better constrain ($\\dot{M}_{out}$/$\\dot{M}_{acc}$). The outflow is spatially resolved in the $[SII]\\lambda \\lambda 6716,6731$ lines and is detected out to $\\sim$ 1\\farcs6 in the blue-shifted lobe and ~ 1" in the red-shifted lobe. The asymmetry between the two lobes is confirmed although the velocity as...

  6. Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217A

    Energy Technology Data Exchange (ETDEWEB)

    Gandhi, Prafull S.; Page, Michael J.; Chen, Zhiwei; Bush-Pelc, Leslie; Di Cera, Enrico; (WU-MED)

    2009-09-15

    The thrombin mutant W215A/E217A (WE) is a potent anticoagulant both in vitro and in vivo. Previous x-ray structural studies have shown that WE assumes a partially collapsed conformation that is similar to the inactive E* form, which explains its drastically reduced activity toward substrate. Whether this collapsed conformation is genuine, rather than the result of crystal packing or the mutation introduced in the critical 215-217 {beta}-strand, and whether binding of thrombomodulin to exosite I can allosterically shift the E* form to the active E form to restore activity toward protein C are issues of considerable mechanistic importance to improve the design of an anticoagulant thrombin mutant for therapeutic applications. Here we present four crystal structures of WE in the human and murine forms that confirm the collapsed conformation reported previously under different experimental conditions and crystal packing. We also present structures of human and murine WE bound to exosite I with a fragment of the platelet receptor PAR1, which is unable to shift WE to the E form. These structural findings, along with kinetic and calorimetry data, indicate that WE is strongly stabilized in the E* form and explain why binding of ligands to exosite I has only a modest effect on the E*-E equilibrium for this mutant. The E* {yields} E transition requires the combined binding of thrombomodulin and protein C and restores activity of the mutant WE in the anticoagulant pathway.

  7. How to Prevent the JT8D-217A/C Aircraft Enginefrom Overheating%如何防止JT8D-217A/C发动机超温

    Institute of Scientific and Technical Information of China (English)

    黄莹

    2001-01-01

    In addressing the overheating problem found in the JT8D-217A/C aircraft engine China Northern Airlines has worked out a take-off EGT margin monitoring plan intended to prevent this kind of engine from overheating. The results show that the plan is effective and satisfactory.%针对JT8D-217A/C发动机超温现象发生的原因,制定了JT8D-217A/C发动机起飞EGT裕度监控方案,并利用此方案监控发动机,在中国北方航空公司应用取得了良好的效果。

  8. Expressions and significance of ZNF217 in papillary thyroid carcinoma%锌指蛋白217在甲状腺乳头状癌组织中的表达及意义

    Institute of Scientific and Technical Information of China (English)

    张丽婷; 吴文艺; 王朝阳; 黄种心; 朱世泽

    2013-01-01

    Objective To investigate the expression and clinical significance of zinc finger gene 217 (ZNF217) in human papillary thyroid carcinoma.Methods The expressions of ZNF217 mRNA and protein were detected by quantitative realtime PCR and Western blot in papillary thyroid carcinoma tissues (n =20) and adjacent normal tissues (n =20),and the data were analyzed.Results The expressions of ZNF217 mRNA and protein in papillary thyroid carcinoma were significantly higher than those in adjacent normal tissues (96.72 ± 44.19 vs 4.86 ±3.55,0.994 ± 0.172 vs 0.195 ± 0.061,both P<0.01),being higher in the papillary thyroid carcinoma with capsule invasion compared with that without capsule invasion (P<0.01).The expressions of ZNF217 mRNA and protein in papillary thyroid carcinoma were not related to gender,age,tumor size,TNM stage or lymph node metastasis (all P>0.05).Conclusions The overexpression of ZNF217 may be associated with the oncogenesis and progress of papillary thyroid carcinoma and capsule invasion,and thus is expected to become a new target for prevention and treatment of papillary thyroid carcinoma.%目的 探讨锌指蛋白217 (ZNF217)在人类甲状腺乳头状癌组织中的表达及其意义.方法 利用实时荧光定量PCR法和Western印迹法检测20例甲状腺乳头状癌组织及相应的20例癌旁正常组织中ZNF217的mRNA和蛋白表达水平,并进行统计学分析.结果 ZNF217 mRNA和蛋白在甲状腺乳头状癌组织中的表达显著高于癌旁正常甲状腺组织(96.72±44.19对4.86±3.55,0.994±0.172对0.195±0.061,均P<0.01),在甲状腺乳头状癌包膜侵犯组高于无包膜侵犯组(P<0.01).ZNF217 mRNA和蛋白的表达与患者的性别、年龄、肿瘤大小、TNM分期及有无淋巴结转移均无关(均P>0.05).结论 ZNF217的过表达可能与甲状腺乳头状癌的发生发展和包膜侵犯有关,有望成为甲状腺乳头状癌预防和治疗的一个新的靶点.

  9. HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlr{sup −/−} mice

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Junghyun; Kim, Chan-Sik; Jo, Kyuhyung [Korean Medicine Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon (Korea, Republic of); Cho, Yun-Seok; Kim, Hyun-Gyu; Lee, Geun-Hyeog [Research and Development Center, Hanlim Pharm. Co. Ltd., 1656-10, Seocho-dong, Seocho-gu, Seoul (Korea, Republic of); Lee, Yun Mi; Sohn, Eunjin [Korean Medicine Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon (Korea, Republic of); Kim, Jin Sook, E-mail: jskim@kiom.re.kr [Korean Medicine Based Herbal Drug Development Group, Herbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon (Korea, Republic of)

    2015-01-02

    Highlights: • HL-217 is a new synthetic topical anti-angiogenic agent. • HL-217 attenuated subretinal neovascularization in Vldlr{sup −/−} mice. • HL-217 blocked the binding of PDGF-BB to PDGFRβ. - Abstract: HL-217 is a new synthetic angiogenesis inhibitor. Platelet derived growth factor (PDGF) is a vasoactive factor and has been implicated in proliferative retinopathies. In this study, we examined the mechanism of action and efficacy of topical application of HL-217 on subretinal neovascularization in very low-density lipoprotein receptor knockout (Vldlr{sup −/−}) mice. In three-week-old male Vldlr{sup −/−} mice, HL-217 (1.5 or 3 mg/ml) was administered twice per day for 4 weeks by topical eye drop instillation. Neovascular areas were then measured. We used a protein array to evaluate the expression levels of angiogenic factors. The inhibitory effect of HL-217 on the PDGF-BB/PDGFRβ interaction was evaluated in vitro. The neovascular area in the Vldlr{sup −/−} mice was significantly reduced by HL-217. Additionally, HL-217 decreased the expression levels of PDGF-BB protein and VEGF mRNA. Moreover, HL-217 dose-dependently inhibited the PDGF-BB/PDGFRβ interaction (IC{sub 50} = 38.9 ± 0.7 μM). These results suggest that HL-217 is a potent inhibitor of PDGF-BB. HL-217, when applied topically, is an effective inhibitor of subretinal neovascularization due to its ability to inhibit the pro-angiogenic effects of PDGF-BB.

  10. HL-217, a new topical anti-angiogenic agent, inhibits retinal vascular leakage and pathogenic subretinal neovascularization in Vldlr−/− mice

    International Nuclear Information System (INIS)

    Highlights: • HL-217 is a new synthetic topical anti-angiogenic agent. • HL-217 attenuated subretinal neovascularization in Vldlr−/− mice. • HL-217 blocked the binding of PDGF-BB to PDGFRβ. - Abstract: HL-217 is a new synthetic angiogenesis inhibitor. Platelet derived growth factor (PDGF) is a vasoactive factor and has been implicated in proliferative retinopathies. In this study, we examined the mechanism of action and efficacy of topical application of HL-217 on subretinal neovascularization in very low-density lipoprotein receptor knockout (Vldlr−/−) mice. In three-week-old male Vldlr−/− mice, HL-217 (1.5 or 3 mg/ml) was administered twice per day for 4 weeks by topical eye drop instillation. Neovascular areas were then measured. We used a protein array to evaluate the expression levels of angiogenic factors. The inhibitory effect of HL-217 on the PDGF-BB/PDGFRβ interaction was evaluated in vitro. The neovascular area in the Vldlr−/− mice was significantly reduced by HL-217. Additionally, HL-217 decreased the expression levels of PDGF-BB protein and VEGF mRNA. Moreover, HL-217 dose-dependently inhibited the PDGF-BB/PDGFRβ interaction (IC50 = 38.9 ± 0.7 μM). These results suggest that HL-217 is a potent inhibitor of PDGF-BB. HL-217, when applied topically, is an effective inhibitor of subretinal neovascularization due to its ability to inhibit the pro-angiogenic effects of PDGF-BB

  11. Fluid-mixing studies in a hexagonal 217-pin wire-wrapped rod bundle. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Symolon, P.D.; Todreas, N.E.

    1981-02-01

    Mixing, pressure drop, and flow split experiments were performed on a 217 pin LMFBR fuel bundle with a pitch to diameter ratio of 1.25 and a lead length of 12 inches. It was found that the turbulent flow data could best be characterized by the energy parameter C/sub 1L/=.106, which is 9% higher than the value from the correlation of Chiu et al. Chiu's correlation was developed on a data base of 61 and 91 pins. The spread of existing data about the correlation is +- 25%, but the error band on our data is expected to be less (approx. +- 10% since injection depth effects were not previously considered). This result is consistent with the concept of increased swirl flow in larger bundles (more pins).

  12. 77 FR 14584 - Eleventh Meeting: RTCA Special Committee 217, Joint With EUROCAE Working Group-44, Terrain and...

    Science.gov (United States)

    2012-03-12

    ... are to report on activities that have occurred since the September meeting. For Working Groups and... Working Group--44, Terrain and Airport Mapping Databases. SUMMARY: The FAA is issuing this notice to advise the public of the Eleventh meeting of RTCA Special Committee 217, Joint with EUROCAE Working...

  13. A computer program to generate equations of motion matrices, L217 (EOM). Volume 2: Supplemental system design and maintenance document

    Science.gov (United States)

    Clemmons, R. E.; Kroll, R. I.

    1979-01-01

    The equations of motion program L217 (EOM) is described. The program formulates the matrix coefficients for a second order linear differential equation which describes the motion of an airplane relative to its level equilibrium flight condition. Aerodynamic data from FLEXSTAB or Doublet Lattice (L216) programs are used to derive the equations for quasi-steady or complete unsteady aerodynamics.

  14. Clinical feature analysis on 217 patients with subjective tinnitus%217例主观性耳鸣的临床特征分析

    Institute of Scientific and Technical Information of China (English)

    陈玲; 杨海弟; 区永康

    2011-01-01

    目的 研究分析耳鸣患者的临床特征及听力学特点,比较不同类型耳鸣的掩蔽试验效果,探索耳鸣的个性化治疗.方法 对我科门诊及住院的主观性耳鸣患者217例,常规病史调查,同时行纯音测听、耳声发射、耳鸣检测及掩蔽,分析耳鸣患者的临床特征,评估各类耳鸣掩蔽试验的情况.结果 耳鸣在人群高发年龄段为36~ 55岁,占24%.男女比例分别为48%及52%,耳鸣发生侧别以左侧最常见(42%),双侧耳鸣次之(30%),右侧耳鸣最少(28%).城市人口及脑力劳动者居多,分别占77%和68%.病程中以慢性耳鸣患者(病程>1年)最多(占46%).耳鸣高频及低频耳鸣患者掩蔽最为有效,有效率分别为71.6%及73.6%,而中频耳鸣掩蔽有效率仅有52.2%,夫特曼曲线类型与掩蔽试验阳性率明显相关,由Ⅰ型掩蔽阳性率为89%降至Ⅴ型掩蔽阳性率为11.7%.结论 耳鸣患者各项特征与掩蔽试验、耳鸣频率等有较大相关性,可作为耳鸣治疗效果的预测指标.Feldman曲线类型在耳鸣诊断和治疗方面有很大应用价值及指导意义,是预测耳鸣掩蔽是否有效的一个重要指标,也是选择耳鸣个体化治疗的一个重要参考依据.%Objective To analysis the clinical feature and audiology feature of patients with subjective tinnitus,compare masking,screening effectiveness of various kinds tinnitus,and search for the individual treatment ways for subjective tinnitus.Methods 217 patients in our hospistor were performed pure tone test,DPOAE,tinnitus determination,and tinnitus masking including pitch matching,intensity matching,Feldmann masking curve,and residual inhibition test with TinniTestTM.Results The prevalence rate is higher in female (52%).Tinnitts occur to the left side more common (42%),followed by bilateral ears (30%) and the right side (28%).The urban population ( 77% ) and mental worker ( 68% ) were primary in patients.The patients

  15. Factors Associated with Coronary Artery Disease in Young Population (Age≤40):Analysis with 217 Cases

    Institute of Scientific and Technical Information of China (English)

    Wei-xian Yang; Zheng Yang; Yong-jian Wu; Shu-bin Qiao; Yue-jin Yang; Ji-lin Chen

    2014-01-01

    Objective To investigate the relevant factors of coronary artery disease (CAD) in young people under 40 years of age. Methods The study population was 292 young patients accepting coronary angiography in Fuwai Hospital from July to December 2006, including 272 men and 20 women, with the mean age being 36.7±3.7 years. The diagnosis of CAD was made in the cases presenting ≥50%stenosis in coronary lumen in coronary angiography. Based on the diagnosis, 217 patients (204 men, 13 women) were assigned to CAD group, and 75 (68 men, 7 women) to non-CAD group. Clinical data and metabolic characteristics of the patients were collected and analyzed using t-test,χ2 test, and multinomial logistic regression with SPSS 8.0 software. Results Most study subjects were current smokers (209/292, 71.6%), and more than half had body mass index (BMI)>24 kg/m2 (230/292, 78.8%) and usually took high-fat diet (162/292, 55.5%). The proportion of heavy smokers (smoking history ≥10 years and ≥20 cigarettes per day) were significantly higher in the CAD group than in the non-CAD group [20.7%(45/217) vs. 9.3%(7/75), P=0.015)]. Heavy smoking [odds ratio (OR), 1.89;95%confidence interval (CI), 1.74-2.05], hypertension (OR, 1.56;95%CI, 1.48-1.65), alcohol (OR, 1.37;95%CI, 1.30-1.46), type 2 diabetes mellitus (OR, 1.37;95%CI, 1.25-1.50), high-fat diet (OR, 1.35;95% CI, 1.28-1.43), and BMI>24 kg/m2 (OR, 1.09;95% CI, 1.03-1.17) were factors related to CAD in the young patients (all P Conclusions Heavy smoking, hypertension, alcohol consumption, type 2 diabetes mellitus, high-fat diet and BMI>24 kg/m2 were significantly related to CAD in patients aged ≤ 40, with heavy smoking presenting the highest OR. Metabolic syndrome and inflammation were also more common in young CAD patients than in non-CAD patients.

  16. Echomorphology of cardiomyopathy: review of 217 cases from 1999 to 2010

    International Nuclear Information System (INIS)

    Objective: To study echocardiogram features of different types of cardiomyopathy presenting over a 12 year period at a single centre in Peshawar. Methods: The series comprised a retrospective review of 13,788 consecutive echocardiograms carried out at the Muhammadi Hospital International Medical Research Centre, Hayatabad, Peshawar, from January 1999 to December 2010. Patients were split into two: Group I with paediatric and adolescent cases (0-18 years) and Group II with adults (>18 years). In the adult group, women with peripartum cardiomyopathy were subdivided into two groups of 18-30 years and 30 to 44 years. Standard Echo B and M modes and Doppler parameters were recorded to ascertain the diagnoses of common primary and secondary cardiomyopathies. Patients with myocarditis with chambers dilatation and global dysfunction, and cardiopathy associated with major cardiovascular diseases were excluded. SPSS 14 was used for statistical analysis. Results: Cardiomyopathy was diagnosed in 217 (1.57%) cases. There were 144 (66%) cases of dilated cardiomyopathy with a mean age of 13+-14.8 years; 17 (8%) cases of hypertrophic cardiomyopathy with a mean age of 12+-11.5 years; and 7 (3%) cases of restrictive cardiomyopathy with a mean age of 31+-7.8 years. Primary cardiac amyloidosis was confirmed in 9 (4%) cases, and peripartum cardiomyopathy in 25 (11%) females. Rare subtypes were found in 15 (7%) cases. Conclusion: DCM was the most frequently diagnosed subtype of cardiomyopathy followed by HCM in both the adult and paediatric age groups. (author)

  17. BXERL photo-injector based on a 217 MHz normal conducting RF gun

    Institute of Scientific and Technical Information of China (English)

    LIU Sheng-Guang; HUANG Tong-Ming; XU Jin-Qiang

    2011-01-01

    The Beijing X-ray Energy Recovery Linac(BXERL)test facility is proposed in Institute of High Physics(IHEP).In this proposal,the main linac requires the injector to provide an electron beam with 5 MeV energy and 10 mA average current.An injector based on DC gun technology is the first candidate electron source for BXERL.However,the field emission in the DC gun cavity makes it much more difficult to increase the high voltage to more than 500 kV.Another technology based on a 217 MHz normal conducting RF gun is proposed as the backup injector for this test facility.We have designed this RF gun with 2D SUPERFISH code and 3D MICROWAVE STUDIO code.In this paper,we present the optimized design of the gun cavity,the gun RF parameters and the set-up of the whole injector system.The detailed beam dynamics have been done and the simulation results show that the injector can generate electron bunches with RMS normalizedemittance 1.0 πmm.mrad,bunch length 0.77 mm,beam energy 5.0 MeV and energy spread 0.60%.

  18. Magnetic Microstructures of 2:17 Type Sm(Co,Fe,Cu,Zr)z Magnets Detected by Magnetic Force Microscopy

    Institute of Scientific and Technical Information of China (English)

    Xia Ailin; Guo Zhaohui; Li Wei; Han Baoshan

    2006-01-01

    The magnetic microstructures of 2:17 type Sm(Co,Fe,Cu,Zr)z magnets were detected by magnetic force microscopy.Comparing the microstructures of the specimens coated with and without Ta thin film before and after heat-treatment, it is found that: (a) as a protection layer, Ta coating layer about 20 nm thick can effectively restrain Sm volatilization under high temperature;(b) the stress built in the 2:17 type Sm-Co magnets during specimen preparation only affects some local parts of the domain structures;(c) the magnetic microstructures vary largely for specimens heat-treated at high temperature without Ta film coating due to Sm volatilization.In addition, by comparing with high coercivity Fe-Pt point tips, it is found that the Co-Cr thin-film tips are not suitable for detecting the magnetic microstructures of strong permanent magnets.

  19. A computer program to generate equations of motion matrices, L217 (EOM). Volume 1: Engineering and usage

    Science.gov (United States)

    Kroll, R. I.; Clemmons, R. E.

    1979-01-01

    The equations of motion program L217 formulates the matrix coefficients for a set of second order linear differential equations that describe the motion of an airplane relative to its level equilibrium flight condition. Aerodynamic data from FLEXSTAB or Doublet Lattice (L216) programs can be used to derive the equations for quasi-steady or full unsteady aerodynamics. The data manipulation and the matrix coefficient formulation are described.

  20. Bloodstream infection following 217 consecutive systemic-enteric drained pancreas transplants

    Directory of Open Access Journals (Sweden)

    Mark Walter

    2006-08-01

    Full Text Available Abstract Background Combined kidney pancreas transplantation (PTx evolved as excellent treatment for diabetic nephropathy. Infections remain common and serious complications. Methods 217 consecutive enteric drained PTxs performed from 1997 to 2004 were retrospectively analyzed with regard to bloodstream infection. Immunosuppression consisted of antithymocyteglobuline induction, tacrolimus, mycophenolic acid and steroids for the majority of cases. Standard perioperative antimicrobial prophylaxis consisted of pipercillin/tazobactam in combination with ciprofloxacin and fluconazole. Results One year patient, pancreas and kidney graft survival were 96.4%, 88.5% and 94.8%, surgical complication rate was 35%, rejection rate 30% and rate of infection 59%. In total 46 sepsis episodes were diagnosed in 35 patients (16% with a median onset on day 12 (range 1–45 post transplant. Sepsis source was intraabdominal infection (IAI (n = 21, a contaminated central venous line (n = 10, wound infection (n = 5, urinary tract infection (n = 2 and graft transmitted (n = 2. Nine patients (4% experienced multiple episodes of sepsis. Overall 65 pathogens (IAI sepsis 39, line sepsis 15, others 11 were isolated from blood. Gram positive cocci accounted for 50 isolates (77%: Coagulase negative staphylococci (n = 28, i.e. 43% (nine multi-resistant, Staphylococcus aureus (n = 11, i.e. 17% (four multi-resistant, enterococci (n = 9, i.e. 14% (one E. faecium. Gram negative rods were cultured in twelve cases (18%. Patients with blood borne infection had a two year pancreas graft survival of 76.5% versus 89.4% for those without sepsis (p = 0.036, patient survival was not affected. Conclusion Sepsis remains a serious complication after PTx with significantly reduced pancreas graft, but not patient survival. The most common source is IAI.

  1. Reduction of F1 Neuronal Excitability by Exposure to 217 Hz Magnetic Fields from GSM 900 Mobile Phone

    Directory of Open Access Journals (Sweden)

    Mehri Kaviani Moghadam

    2009-01-01

    Full Text Available Objective: The aim of this study was to investigate the effects of a 217 Hz magnetic field ofmobile phone GSM 900 exposure on the bioelectric activity of F1 neuronal cells of the landsnail.Materials and Methods: According to the magnetic field measurement of the mobile phone,a range of flux intensities of magnetic fields (0.46 - 229 μT at a frequency of 217 Hz wasproduced by magnetic field coils. The bioelectrical activity of F1 nerve cells at different timeintervals was recorded, using intracellular recording under current clamp conditions in control,sham and field exposed groups.Results: Magnetic field exposure decreased the amplitude of action potential and the firingfrequency of F1 nerve cells. Furthermore, it resulted in a significant (p<0.05 increase inthe amplitude of after hyperpolarization (AHP and duration of action potential. Change inthe cell’s electrophysiological parameters was associated with a decrease in neuronal excitability.Magnetic field exposure affected also the resting membrane potential of F1 cells in abimodal fashion, including depolarization and hyperpolarization. Considering the exposurecondition, most of the alterations in the electrical activity of F1 nerve cells induced by magneticfields exposure were reversible.Conclusion: These findings suggest that 217 Hz magnetic fields of mobile phones with differentintensities affect the spontaneous bioelectrical activity of F1 nerve cells and exert inhibitoryeffects on neuronal excitability. There is evidence for the existence of an amplitudewindow and these electrophysiological alterations occur within this amplitude window. Thereversibility of the magnetic field- induced most electrophysiological alterations in the neuronalbehavior under our experimental conditions was observed.

  2. The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Yu; Wong, Nicholas; Guan, Yinghui; Salamanca, Clara M.; Cheng, Jung Chien; Lee, Jonathan M.; Gray, Joe W.; Auersperg, Nelly

    2008-04-25

    Ovarian epithelial carcinomas (OEC) frequently exhibit amplifications at the 20q13 locus which is the site of several oncogenes, including the eukaryotic elongation factor EEF1A2 and the transcription factor ZNF217. We reported previously that overexpressed ZNF217 induces neoplastic characteristics in precursor cells of OEC. Unexpectedly, ZNF217, which is a transcriptional repressor, enhanced expression of eEF1A2. In this study, array comparative genomic hybridization, single nucleotide polymorphism and Affymetrix analysis of ZNF217-overexpressing cell lines confirmed consistently increased expression of eEF1A2 but not of other oncogenes, and revealed early changes in EEF1A2 gene copy numbers and increased expression at crisis during immortalization. We defined the influence of eEF1A2 overexpression on immortalized ovarian surface epithelial cells, and investigated interrelationships between effects of ZNF217 and eEF1A2 on cellular phenotypes. Lentivirally induced eEF1A2 overexpression caused delayed crisis, apoptosis resistance and increases in serum-independence, saturation densities, and anchorage independence. siRNA to eEF1A2 reversed apoptosis resistance and reduced anchorage independence in eEF1A2-overexpressing lines. Remarkably, siRNA to eEF1A2 was equally efficient in inhibiting both anchorage independence and resistance to apoptosis conferred by ZNF217 overexpression. Our data define neoplastic properties that are caused by eEF1A2 in nontumorigenic ovarian cancer precursor cells, and suggest that eEF1A2 plays a role in mediating ZNF217-induced neoplastic progression.

  3. Knockdown of lncRNA-ATB suppresses autocrine secretion of TGF-β2 by targeting ZNF217 via miR-200c in keloid fibroblasts.

    Science.gov (United States)

    Zhu, Hua-Yu; Bai, Wen-Dong; Li, Chao; Zheng, Zhao; Guan, Hao; Liu, Jia-Qi; Yang, Xue-Kang; Han, Shi-Chao; Gao, Jian-Xin; Wang, Hong-Tao; Hu, Da-Hai

    2016-01-01

    Abnormally high activation of transforming growth factor-β (TGF-β) signaling has been demonstrated to be involved in the initiation and progression of keloids. However, the functional role of long non-coding RNA (lncRNA)-activated by TGF-β (lncRNA-ATB) in keloids has not been documented. Here we investigated the role of lncRNA-ATB in the autocrine secretion of TGF-β in keloid fibroblasts (KFs) and explored the underlying molecular mechanism. Using immunohistochemistry and quantitative RT-PCR analysis, we showed that lncRNA-ATB and ZNF217, a transcriptional activator of TGF-β, were overexpressed and miR-200c, which targets ZNF217, was under-expressed in keloid tissue and keloid fibroblasts. Through gain- and loss-of-function studies, we demonstrated that knockdown of lncRNA-ATB decreased autocrine secretion of TGF-β2 and ZNF217 expression but upregulated expression of miR-200c in KFs. Stable downregulation of ZNF217 expression decreased the autocrine secretion of TGF-β2. miR-200c was endogenously associated with lncRNA-ATB, and inhibition of miR-200c overcame the decrease in ZNF217 expression in KFs. Taken together, these findings indicate that lncRNA-ATB governs the autocrine secretion of TGF-β2 in KFs, at least in part, by downregulating the expression level of ZNF217 via miR-200c, suggesting a signaling axis consisting of lncRNA-ATB/miR-200c/ZNF217/TGF-β2. These findings may provide potential biomarkers and targets for novel diagnostic and therapeutic approaches for keloids. PMID:27090737

  4. Production of D0(1863) mesons in 217 GeV/c pi-minus proton interactions

    International Nuclear Information System (INIS)

    This thesis reports on the analysis of data obtained during FNAL experiment E369. The Chicago Cyclotron Magnet Spectrometer Facility was used to perform a search for the hadronic production of charmed D mesons. A 217 Gev π- beam was incident on a liquid hydrogen target. The trigger required a slow recoil proton in coincidence with a muon. A total of 26 +- 8 neutral D mesons were observed through their K0π+π- decay mode. The distributions of Feynman X, missing mass, and momentum transfer to the recoil proton were consistent with diffractive production. Cross sections were calculated based on a diffractive model

  5. Reaction natYb+48Ca->217Th+3n: auto calibration process for DSSSD detector application (particular case)

    CERN Document Server

    Tsyganov, Yu

    2015-01-01

    The Dubna Gas-Filled Recoil Separator (DGFRS) is the mostly effective setup in use for the field of synthesis of superheavy elements. Application of DSSSD detector provides more precise energy and position detection for both implanted recoils and their alpha decays. To minimize contribution of background products the method of fctive correlation is applied at the DGFRS. To apply this method a precise calibration for 48 front strips is strongly required. Method of three peaks auto calibration is proposed with a first approximation step with 9.26 MeV 217Th peaks. Examples of alpha-decay original spectra and spectra after filtration procedures are presented.

  6. Jurisprudential Analysis on the 217th Article of Criminal Law about “Reproducing and Distributing”%对刑法第217条关于“复制发行”规定的法理分析

    Institute of Scientific and Technical Information of China (English)

    王泽众

    2015-01-01

    不论是学术界还是实务界,对刑法第217条关于“复制发行”规定的含义都存在多种理解方式。从法理的应然角度和刑事政策的实然角度分析,“复制发行”应当理解为包括单独的复制行为或既复制又发行行为两种情况,而单独的非法发行行为属于销售侵权复制品罪的范畴,应当适用刑法第218条的规定。%Both in the theory and practice fields,there are many ways of understanding the 217th article of the criminal law about the“reproducing and distributing”.Analyzing from the necessities of jurisprudence and the realities of criminal policies,“reproducing and distributing”behavior ought to be interpreted as two situations:reproducing behavior or both reproducing and distributing behavior. The simple distributing behavior belongs to the category of crime of selling pirated goods that should apply the provisions of the 218th article of the criminal law.

  7. Decay of the ground state and the 29/2+ isomer in 217Ac and G factor measurements by perturbed angular distribution of α-particles

    International Nuclear Information System (INIS)

    The nucleus 217Ac was studied using the 205Tl(16O, 4n), 206Pb (15N, 4n) and 209Bi (12C, 4n) reactions. The measurements included α-γ, γ-γ, α-ce and ce-ce coincidence experiments as well as γ-ray and α-particle perturbed angular distribution studies. Results are: g(217Acsup(gs))=+0.85 (1) and Tsub(1/2)(217Acsup(gs))=69(4) ns, the shortest known α-decay of a ground state. 217Agsup(m) decays mainly by a γ cascade, but also by α-emission to the single particles states πhsub(9/2), fsub(7/2), isub(13/2) of 213Fr. Spins and parities of levels to the 29/2+ isomer at 2013 keV with Tsub(1/2)=740(40)ns and g=+0.347(5) are determined. The level scheme of 217Ac and the α decay of N=128 isotones are discussed. (orig.)

  8. Magnetic domain structures of precipitation-hardened SmCo 2:17-type sintered magnets: Heat treatment effect

    Institute of Scientific and Technical Information of China (English)

    Li Xiu-Mei; Fang Yi-Kun; Guo Zhao-Hui; Liu Tao; Guo Yong-Quan; Li Wei; Han Bao-Shan

    2008-01-01

    The typical magnetic domains of Sm(CobalFe0.25Cu0.07Zr0.02)7.4 magnets quenched through various heat-treatment steps have been revealed by using magnetic force microscopy (MFM). For the specimens in which the nominal c-axis is perpendicular to the imaging plane, the domain configurations change from plate-like for the as-sintered mag-net to corrugation and spike-like for the homogenized one, and then to a coarse and finally to a finer domain structure when isothermally aged at 830℃ and then annealed at 400℃. However, only plate-like domains can be detected on the surfaces with the nominal c-axis parallel to the imaging plane. The finer domain (so-called interaction domain) is a characteristic magnetic domain pattern of the Sm-Co 2:17-type magnets with high coercivities. Domain walls in a zigzag shape are revealed by means of MFM in final bulk Sm-Co 2:17-type sintered magnets.

  9. Roflumilast: APTA 2217, B9302-107, BY 217, BYK 20869.

    Science.gov (United States)

    2004-01-01

    Roflumilast [APTA 2217, B9302-107, BY 217, BYK 20869] is a selective phosphodiesterase IV inhibitor. It is being developed by Altana Pharma (formerly Byk Gulden), a subsidiary of Altana Group, as an orally administered therapy for asthma, chronic obstructive pulmonary disease (COPD), allergic rhinitis and psoriasis. The drug is awaiting regulatory approval in Europe for the treatment of asthma and COPD. Byk Gulden has stated that roflumilast relieves asthma symptoms through both an anti-inflammatory effect and a muscle relaxant effect. Roflumilast has potential as first-line long-term therapy in mild-to-moderate COPD and as additive long-term therapy in moderate-to-severe COPD. Altana has stated that roflumilast is to be marketed under the brand name Daxas. Altana Group and Pharmacia Corporation (now Pfizer) signed an agreement on 22 April 2002 to collaborate on the development and commercialisation of roflumilast for the treatment of respiratory disorders, including asthma and COPD. The companies will jointly develop the drug for the US, Europe and other markets. Pharmacia will co-ordinate development in the US and Altana will co-ordinate development in Europe. After approval of the drug, Pharmacia and Altana will jointly launch and promote roflumilast in the US, Europe and elsewhere. Altana will receive an upfront payment and additional milestone payments. Altana additionally has the option to co-promote Pharmacia products in the US and elsewhere. On 16 April 2003, Pharmacia Corporation was acquired by, and merged into, Pfizer. In November 2002, Altana and Tanabe Seiyaku signed an agreement to collaborate on the development and commercialisation of roflumilast for the treatment of respiratory diseases, including asthma and COPD. Tanabe Seiyaku and Altana will develop roflumilast for asthma and COPD in Japan, and will jointly launch and co-promote roflumilast in Japan following regulatory approval. Roflumilast has been in multinational phase III clinical studies

  10. Results of the independent verification of radiological remedial action at 217 South 2nd East Street, Monticello, Utah (MS00097)

    International Nuclear Information System (INIS)

    In 1980 the site of a vanadium and uranium mill at Monticello, Utah, was accepted into the US Department of Energy's (DOE's) Surplus Facilities Management Program, with the objectives of restoring the government-owned mill site to safe levels of radioactivity, disposing of or containing the tailings in an environmentally safe manner, and performing remedial actions on off-site (vicinity) properties that had been contaminated by radioactive material resulting from mill operations. During 1985 and 1986, UNC Geotech, the remedial action contractor designated by DOE, performed remedial action on the vicinity property at 217 South 2nd East Street, Monticello, Utah. The Pollutant Assessments Group (PAG) of Oak Ridge National Laboratory was assigned the responsibility of verifying the data supporting the adequacy of remedial action and confirming the site's compliance with DOE guidelines. The PAG found that the site successfully meets the DOE remedial action objectives. Procedures used by PAG are described. 3 refs., 2 tabs

  11. Draft Genome Sequences of Seven Bacterial Strains Isolated from a Polymicrobial Culture of Coccolith-Bearing (C-Type) Emiliania huxleyi M217

    Science.gov (United States)

    Rosana, Albert Remus R.; Orata, Fabini D.; Xu, Yue; Simkus, Danielle N.; Bramucci, Anna R.; Boucher, Yan

    2016-01-01

    Strains of Rhodobacteraceae, Sphingomonadales, Alteromonadales, and Bacteroidetes were isolated from a polymicrobial culture of the coccolith-forming (C-type) haptophyte Emiliania huxleyi strain M217. The genomes encode genes for the production of algal growth factors and the consumption of their hosts’ metabolic by-products, suggesting that the polymicrobial culture harbors many symbiotic interactions. PMID:27417845

  12. Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma.

    Science.gov (United States)

    Collins, C; Rommens, J M; Kowbel, D; Godfrey, T; Tanner, M; Hwang, S I; Polikoff, D; Nonet, G; Cochran, J; Myambo, K; Jay, K E; Froula, J; Cloutier, T; Kuo, W L; Yaswen, P; Dairkee, S; Giovanola, J; Hutchinson, G B; Isola, J; Kallioniemi, O P; Palazzolo, M; Martin, C; Ericsson, C; Pinkel, D; Albertson, D; Li, W B; Gray, J W

    1998-07-21

    We report here the molecular cloning of an approximately 1-Mb region of recurrent amplification at 20q13.2 in breast cancer and other tumors and the delineation of a 260-kb common region of amplification. Analysis of the 1-Mb region produced evidence for five genes, ZNF217, ZNF218, and NABC1, PIC1L (PIC1-like), CYP24, and a pseudogene CRP (Cyclophillin Related Pseudogene). ZNF217 and NABC1 emerged as strong candidate oncogenes and were characterized in detail. NABC1 is predicted to encode a 585-aa protein of unknown function and is overexpressed in most but not all breast cancer cell lines in which it was amplified. ZNF217 is centrally located in the 260-kb common region of amplification, transcribed in multiple normal tissues, and overexpressed in all cell lines and tumors in which it is amplified and in two in which it is not. ZNF217 is predicted to encode alternately spliced, Kruppel-like transcription factors of 1,062 and 1,108 aa, each having a DNA-binding domain (eight C2H2 zinc fingers) and a proline-rich transcription activation domain. PMID:9671742

  13. The Planck-ATCA Co-eval Observations (PACO) project: analysis of radio source properties between 5 and 217 GHz

    CERN Document Server

    Massardi, Marcella; Bonavera, Laura; De Zotti, Gianfranco; Lopez-Caniego, Marcos; Galluzzi, Vincenzo

    2015-01-01

    The Planck-ATCA Co-eval Observations (PACO) project has yielded observations of 464 sources with the Australia Telescope Compact Array (ATCA) between 4.5 and 40 GHz. The main purpose of the project was to investigate the spectral properties of mm-selected radio sources at frequencies below and overlapping with the ESA's Planck satellite frequency bands, minimizing the variability effects by observing almost simultaneously with the first two Planck all-sky surveys. In this paper we present the whole catalogue of observations in total intensity. By comparing PACO with the various measures of Planck Catalog of Compact Sources (PCCS) flux densities we found the best consistency with the PCCS "detection pipeline" photometry (DETFLUX) that we used to investigate the spectral properties of sources from 5 to 217 GHz. Of our sources, 91% have remarkably smooth spectrum, well described by a double power law over the full range. This suggests a single emitting region, at variance with the notion that "flat" spectra resu...

  14. The Planck-ATCA Co-eval Observations project: analysis of radio source properties between 5 and 217 GHz

    Science.gov (United States)

    Massardi, Marcella; Bonaldi, Anna; Bonavera, Laura; De Zotti, Gianfranco; Lopez-Caniego, Marcos; Galluzzi, Vincenzo

    2016-01-01

    The Planck-ATCA Co-eval Observations (PACO) project has yielded observations of 464 sources with the Australia Telescope Compact Array (ATCA) between 4.5 and 40 GHz. The main purpose of the project was to investigate the spectral properties of mm-selected radio sources at frequencies below and overlapping with the ESA's Planck satellite frequency bands, minimizing the variability effects by observing almost simultaneously with the first two Planck all-sky surveys. In this paper we present the whole catalogue of observations in total intensity. By comparing PACO with the various measures of Planck Catalog of Compact Sources (PCCS) flux densities we found the best consistency with the PCCS `detection pipeline' photometry (DETFLUX) that we used to investigate the spectral properties of sources from 5 to 217 GHz. Of our sources, 91 per cent have remarkably smooth spectrum, well described by a double power-law over the full range. This suggests a single emitting region, at variance with the notion that `flat' spectra result from the superposition of the emissions from different compact regions, self-absorbed up to different frequencies. Most of the objects show a spectral steepening above ≃30 GHz, consistent with synchrotron emission becoming optically thin. Thus, the classical dichotomy between flat-spectrum/compact and steep-spectrum/extended radio sources, well established at cm wavelengths, breaks down at mm wavelengths. The mm-wave spectra do not show indications of the spectral break expected as the effect of `electron ageing', suggesting young source ages.

  15. Status of the 7 MeV/u, 217 MHz Injector Linac for the Heidelberg Cancer Therapy Facility

    CERN Document Server

    Schlitt, B; Hutter, G; Klos, F; Lu, Y; Minaev, S A; Mühle, C; Ratzinger, U; Schlitt, B; Tiede, R; Vinzenz, W; Will, C; Zurkan, O

    2004-01-01

    A clinical synchrotron facility for cancer therapy using energetic proton and ion beams (C, He and O) is under construction and will be installed at the Radiologische Universitätsklinik in Heidelberg, Germany, starting in 2005. The status of the ECR ion source systems, the beam line components of the low energy beam transport lines, the 400 keV/u RFQ and the 20 MV IH-cavity as well as the linac rf system will be reported. Two prototype magnets of the linac quadrupole magnets have been built at GSI and have been tested successfully. A test bench for the 1.4 MW, 217 MHz cavity amplifier built by industry has been installed at GSI including a 120 kW driver amplifier which will be used also for high power tests of the RFQ. A test bench for the RFQ using proton beams is presently being set up at the IAP. RF tuning of the 1:2 scaled IH-DTL model as well as Microwave Studio simulations of the model and the power cavity have been also performed at the IAP [1].

  16. Exchange of glutamine-217 to glutamate of Clostridium limosum exoenzyme C3 turns the asparagine-specific ADP-ribosyltransferase into an arginine-modifying enzyme.

    Science.gov (United States)

    Vogelsgesang, Martin; Aktories, Klaus

    2006-01-24

    C3-like ADP-ribosyltransferaseses are produced by Clostridium species, Bacillus cereus, and various Staphylococcus aureus strains. The exoenzymes modify the low-molecular-mass GTPases RhoA, B, and C. In structural studies of C3-like exoenzymes, an ARTT-motif (ADP-ribosylating turn-turn motif) was identified that appears to be involved in substrate specificity and recognition (Han, S., Arvai, A. S., Clancy, S. B., Tainer, J. A. (2001) J. Mol. Biol. 305, 95-107). Exchange of Gln217, which is a key residue of the ARTT-motif, to Glu in C3 from Clostridium limosum results in inhibition of ADP-ribosyltransferase activity toward RhoA. The mutant protein is still capable of NAD-binding and possesses NAD+ glycohydrolase activity. Whereas recombinant wild-type C3 modifies Rho proteins specifically at an asparagine residue (Asn41), Gln217Glu-C3 is capable of ADP-ribosylation of poly-arginine but not poly-asparagine. Soybean trypsin inhibitor, a model substrate for many arginine-specific ADP-ribosyltransferases, is modified by the Gln217Glu-C3 transferase. Also in C3 ADP-ribosyltransferases from Clostridium botulinum and B. cereus, the exchange of the equivalent Gln residue to Glu blocked asparagine modification of RhoA but elicited arginine-specific ADP-ribosylation. Moreover, the Gln217Glu-C3lim transferase was able to ADP-ribosylate recombinant wild-type C3lim at Arg86, resulting in decrease in ADP-ribosyltransferase activity of the wild-type enzyme. The data indicate that the exchange of one amino acid residue in the ARTT-motif turns the asparagine-modifying ADP-ribosyltransferases of the C3 family into arginine-ADP-ribosylating transferases.

  17. Investigating the effects of 217 Hz frequency of cell phone on learning and spatial memory in rats

    Directory of Open Access Journals (Sweden)

    Kohzad S

    2013-03-01

    Full Text Available Background: Extremely low frequency (0-300 Hz fields from power lines, electronic equipment and medical devices, have been reported to produce various biological effects. Global system for mobile (GSM is most largely used in everybody's life. This system utilizes a low frequency band as well as a high frequency range of electromagnetic field. This study investigated the effects of 217 Hz electromagnetic field (the modulating signal in GSM on spatial learning and memory in rat.Methods: Twenty four male Wistar rat (200- 250 g were randomly divided in to three groups as: test, sham and control. Using a Helmholtz coil system, the test group was exposed to a uniform pulsed EMF of 200 µT (micro Tesla intensity for 4 h/day for 21 days (2 time in a day. This procedure was repeated for the sham group but with no field. All groups were trained prior to the day 21 on the 15th day for five days four trial per day in Morris Water-Maze system. Then the probe test was carried out for 60 seconds with no platform.Results: The ANOVA test revealed that no significant differences were found between control and exposed rats in all day of learning acquisition. Also, in probe test for investigating the memory, no significant differences observed. (P≤0.05 is accepted for significant level.Conclusion: This finding is in consistent with previous studies and indicates low frequency band of electromagnetic fields (EMF (200 µT intensity in cell phone may not have any effect on the learning acquisition and spatial memory in rat.

  18. Expression of mRNA and protein of ZNF217 and EF1α and their significance in pathological scar%锌指基因217和翻译延伸因子1α在病理性瘢痕组织中的表达和意义

    Institute of Scientific and Technical Information of China (English)

    吴文艺; 王小影; 张丽婷; 郑志芳; 朱世泽; 王朝阳

    2012-01-01

    目的 探讨锌指基因217(ZNF217)和翻译延伸因子1α(EF1α)在病理性癜痕中的表达及其相互关系,以及它们在瘢痕形成中的作用及机制,为瘢痕防治提供实验依据.方法 利用实时荧光定量聚合酶链式反应(PCR)法、蛋白质免疫印迹(Western印迹)法检测正常皮肤、成熟瘢痕、增生性瘢痕和瘢痕疙瘩组织中ZNF217和EF1α的mRNA、蛋白相对表达水平.结果 正常皮肤、成熟瘢痕、增生性瘢痕和瘢痕疙瘩组织中ZNF217的mRNA及蛋白质相对表达量分别为1.46±0.397、1.45±0.265、4.49±0.999、5.47±0.808;0.276±0.0211、0.299±0.0150、0.743±0.0509、0.747±0.0377.EF1α的mRNA及蛋白质相对表达量分别为1.47±0.469、1.47±0.218、5.10±1.680、5.74±1.920;0.505±0.0371、0.518±0.0153、0.780土0.0369、0.792±0.0290.病理性瘢痕组织中ZNF217的mRNA及蛋白质表达显著高于正常皮肤、成熟瘢痕(P<0.01);病理性瘢痕组织中EF1α的mRNA及蛋白质表达增高,与正常皮肤、成熟瘢痕对照组比较,差异有统计学意义(P<0.01);病理性瘢痕组织中ZNF217的mRNA及蛋白质表达与EF1α的mRNA及蛋白质表达呈正相关.结论 ZNF217在病理性瘢痕组织中表达增高,可能通过调节EF1α等细胞周期调控因子而促进瘢痕组织中细胞的增生,对病理性瘢痕的形成可能起着重要作用.%Objective To study the expression of ZNF217 and EF1α gene in the pathological scars and to investigate role and probable mechanism in the pathogenesis of abnormal scar.Methods Quantitative real-time PCR and Western blot were performed to detect the expression and distribution of mRNA and protein of ZNF217 and EF1α in hypertrophic scar (10 cases),keloid (10 cases),normal scar (10 cases),and normal skin (10 cases),and statistics was used to analyze the data.Results The expression of ZNF217 mRNA and protein in the normal skin,normal scar,hypertrophic scar and keloid were 1.46±0.397,1.45±0.265,4.49±0.999,5.47±0

  19. The Effect of 217 Hz Magnetic Field of Cell Phone with Different Intensities on Apoptosis of Normal and Cancerous Cells Treated with Chemotherapy Drug

    Directory of Open Access Journals (Sweden)

    Mahsa Mansourian

    2012-03-01

    Full Text Available Background: According to the increasing development of home and business electronic equipment in today's world, the biological effects of ELF magnetic fields have been studied at two molecular-cellular and animal- human levels. Considering the therapeutic viewpoint of this study regarding the effects of low-frequency fields of mobile phone, the effect of acute exposure to this field on chemotherapy will be studied.Materials and Methods: In this experimental study, based on measurement of the intensity of the magnetic fields from mobile phones in another research, flux densities of magnetic field of 159.44, 93.25 and 120µ tesla with frequency of 217Hz was generated in magnetic field generator system, and the apoptosis level in K562 cancer cells and healthy cells of lymphocytes was assessed after exposure to field using flow cytometry method. This evaluation method was also performed for the cells treated with bleomycin after exposure to this field.Results: 217 Hz magnetic field exposure significantly increases the rate of apoptosis percentage (p > 0.05 in K562 cancer cells and in two intensities of 120 and 159.44µ tesla compared to the control group, but such effect is not observed in lymphocyte cells. Bleomycin-induced apoptosis percentage following exposure to the mentioned magnetic field shows no significant difference compared to the group of treatment with drug and without field exposure. This lack of significant difference is observed between the groups of drug after field exposure and field alone as well as between groups exposed to field and groups treated with bleomycin.Conclusion: Study results showed that 217 Hz magnetic field of mobile phone can induce apoptosis on cancer cells, but it has no effect on healthy cells. Thus, in order to use mobile phone as an effective factor in their treatment, some studies should be conducted at animal-human level.

  20. VizieR Online Data Catalog: HK photometry in an UCHII region near Sh2-217 (Brand+, 2011)

    Science.gov (United States)

    Brand, J.; Massi, F.; Zavagno, A.; Deharveng, L.; Lefloch, B.

    2010-11-01

    Coordinates and photometric parameters (magnitudes and colours) are presented of the stars located in a molecular condensation on the SW-border of the Galactic HII region Sh2-217. The data were obtained on January 4, 2004 with the 3.58-m Telescopio Nazionale Galileo (TNG; La Palma, Canary Islands, Spain). Near-infrared observations were carried out through H and K' broad-band filters with the camera NICS. The image scale is 0.25arcsec/pixel, yielding a field of view of about 4.2'x4.2'. Observing strategy and exposure times are described in Deharveng et al. (2006A&A...458..191D), the only difference being that the dithering sequence for the H-band images was the same as adopted for K'. The data reduction steps adopted are outlined in Deharveng et al. (2006A&A...458..191D). Aperture photometry was done using the DAOPHOT package in IRAF. We followed the same procedure described in Deharveng et al. (2006A&A...458..191D) to obtain aperture photometry, after which PSF-fitting photometry was performed. Although the seeing was good (<1"), the night was barely photometric, so we calibrated our H, K' photometry with that performed on the same field by Deharveng et al. (2003, Cat. J/A+A/399/1135). We calculated the difference in magnitudes for each coinciding source and plotted it against our derived instrumental H-K'. A colour term was present in K' because of the difference between the K and K' filters. After a best-fit calibration, a residual r.m.s. of about 0.2mag. was present in the difference between our photometry and that of Deharveng et al. (2003, J/A+A/399/1135), probably because of the different seeing and possibly also due to the intrinsic variability of young stars. Our photometry is thus on the same HK standard system as Deharveng et al. (2003, J/A+A/399/1135). Sources with K, H < 11-12 are in the non-linear regime or saturated, but such bright objects are few in number and lie outside the cluster, and are probably foreground stars. The approximate limiting

  1. Epidemiology of Staphylococcus aureus in Bangalore, India: emergence of the ST217 clone and high rate of resistance to erythromycin and ciprofloxacin in the community

    Science.gov (United States)

    Bouchiat, C.; El-Zeenni, N.; Chakrakodi, B.; Nagaraj, S.; Arakere, G.; Etienne, J.

    2015-01-01

    This study aimed to determine the antibiotic susceptibility pattern of Staphylococcus aureus (SA) and the circulating clones in Bangalore, India. Susceptibility testing was performed for all cases of SA infections in a tertiary-care hospital. Panton-Valentine leucocidin (PVL) encoding genes were detected, and sequence type and spa type were determined. Out of the 92 collected strains, 52.2% were methicillin-resistant SA (MRSA), isolated from community-acquired (CA) infections in 60.4% and hospital-acquired (HA) infections in 39.6%. S. aureus isolates were also highly resistant to erythromycin (54.3%) and ciprofloxacin (70.6%) in methicillin-susceptible SA (MSSA) and MRSA, as well as in CA and HA infections. MRSA were found to be significantly more resistant to gentamicin (p <0.001), cotrimoxazole (p <0.001) and ciprofloxacin (p 0.001) than MSSA, but no significant difference was observed between CA- and HA-SA. ST217 appeared as a new emerging and prevalent clone, but ST772 remained the predominant clone, all being PVL-positive isolates. Our study points out the high prevalence of MRSA, even in the community, and the worrying increase of resistance to ciprofloxacin and erythromycin among CA-MSSA. Emergence of clone ST217 is reported for the first time in India. PMID:26110062

  2. All-solid-state continuous-wave frequency doubling Nd:LuVO4/LBO laser with 2.17 W output power at 543 nm

    Science.gov (United States)

    Li, B.; Zhao, L.; Zhang, Y. B.; Zheng, Q.; Zhao, Y.; Yao, Y.

    2013-03-01

    Efficient and compact green-yellow laser output at 543 nm is generated by intracavity frequency doubling of a CW diode-pumped Nd:LuVO4 laser at 1086 nm under the condition of suppressing the higher gain transition near 1064 nm. With 16 W of diode pump power and the frequency-doubling crystal LBO, as high as 2.17 W of CW output power at 543 nm is achieved, corresponding to an optical-to-optical conversion efficiency of 13.6% and the output power stability over 8 hours is better than 2.86%. To the best of our knowledge, this is the highest watt-level laser at 543 nm generated by intracavity frequency doubling of a diode pumped Nd:LuVO4 laser at 1086 nm.

  3. Production of actinium-225 for alpha particle mediated radioimmunotherapy.

    Science.gov (United States)

    Boll, Rose A; Malkemus, Dairin; Mirzadeh, Saed

    2005-05-01

    The initial clinical trials for treatment of acute myeloid leukemia have demonstrated the effectiveness of the alpha emitter (213)Bi in killing cancer cells. Bismuth-213 is obtained from a radionuclide generator system from decay of 10-days (225)Ac parent. Recent pre-clinical studies have also shown the potential application of both (213)Bi, and the (225)Ac parent radionuclide in a variety of cancer systems and targeted radiotherapy. This paper describes our five years of experience in production of (225)Ac in partial support of the on-going clinical trials. A four-step chemical process, consisting of both anion and cation exchange chromatography, is utilized for routine separation of carrier-free (225)Ac from a mixture of (228)Th, (229)Th and (232)Th. The separation of Ra and Ac from Th is achieved using the marcoporous anion exchange resin MP1 in 8M HNO(3) media. Two sequential MP1/NO(3) columns provide a separation factor of approximately 10(6) for Ra and Ac from Th. The separation of Ac from Ra is accomplished on a low cross-linking cation exchange resin AG50-X4 using 1.2M HNO(3) as eluant. Two sequential AG50/NO(3) columns provide a separation factor of approximately 10(2) for Ac from Ra. A 60-day processing schedule has been adopted in order to reduce the processing cost and to provide the highest levels of (225)Ac possible. Over an 8-week campaign, a total of approximately 100 mCi of (225)Ac (approximately 80% of the theoretical yield) is shipped in 5-6 batches, with the first batch typically consisting of approximately 50 mCi. After the initial separation and purification of Ac, the Ra pool is re-processed on a bi-weekly schedule or as needed to provide smaller batches of (225)Ac. The averaged radioisotopic purity of the (225)Ac was 99.6 +/- 0.7% with a (225)Ra content of < or =0.6%, and an average (229)Th content of (4(-4)(+5)) x 10(-5)%.

  4. Malachi’s concern for social justice: Malachi 2:17 and 3:5 and its ethical imperatives for faith communities

    Directory of Open Access Journals (Sweden)

    Blessing O. Bọlọjẹ

    2014-02-01

    Full Text Available Any time humans in any culture consider primary ethical concepts, justice will be to the fore. Much seems to hinge upon it whether human society is to function with any semblance of civil order, security and harmony. When justice is pervasively trampled upon, the very fabric of liveable society crumbles. The apprehension for justice is clearly reflected in almost all of the Old Testament (OT. It is an important theological motif in the OT. This is found in such OT literature as historical, legal, prophetic and wisdom writings. This evidence thus reveals that the apprehension for the issue of justice was one of the many ways by which Israel’s multifaceted social life was knit together throughout its various ancient historical developments. No aspect of the life of Israel was excluded from this kind of apprehension for justice, and Yahweh was understood to be actively involved in its entire phase. This article examines Malachi’s fourth disputation in the light of the lawlessness alluded to in Malachi 2:17 and the corruption of personal and civil morality in Malachi 3:5. In the discussions that follow, this article examines the need for the justice of Yahweh; that is, Yahweh’s righting of past wrongs and the reversal of sinful societal order. The purpose is to enact a communal ethic for those who generously care for the neighbourhood and are firm in their devotion to Him, that is, God.

  5. Effect of Sm-rich liquid phase on magnetic properties and microstructures of sintered 2:17-type Sm-Co magnet

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wenchen; ZHAO Rui; FANG Yikun; ZHOU Mingge; ZHU Minggang; LI Wei

    2011-01-01

    The effect of Sm-rich liquid phase (Sm2Co3) on magnetic properties and microstructure of 2:17-type Sm-Co magnet was studied.Three phases existed in liquid phase ingot,and took on white,dark grey and grey,respectively.It was found that the composition of the grey area was similar to the nominal one.Our results indicated that the optimal composition was obtained at 3 wt.% liquid phase added,and the magnetic properties were Br=11.58 kGs,Hci>26 kOe,(BH)m=29.51 MGOe.Br increased by 3%,Hci was 13 times larger,and (BH)m was 6 times bigger than none liquid phase magnets.Moreover,with the aging time decreasing from 20 to 8 h,the squareness of the demagnetization curves got better,while the coercivity of the samples decreased.It revealed that Sm(Co,Cu)5 phase also precipitated at particle boundaries.It maybe also enhanced the coercivity.

  6. Regulatory Assistance, Stakeholder Outreach, and Coastal and Marine Spatial Planning Activities In Support Marine and Hydrokinetic Energy Deployment: Task 2.1.7 Permitting and Planning Fiscal Year 2012 Year-End Report

    Energy Technology Data Exchange (ETDEWEB)

    Geerlofs, Simon H.; Hanna, Luke A.; Judd, Chaeli R.; Blake, Kara M.

    2012-09-01

    This fiscal year 2012 year-end report summarizes activities carried out under DOE Water Power task 2.1.7, Permitting and Planning. Activities under Task 2.1.7 address the concerns of a wide range of stakeholders with an interest in the development of the MHK industry, including regulatory and resource management agencies, tribes, NGOs, and industry. Objectives for 2.1.7 are the following: • To work with stakeholders to streamline the MHK regulatory permitting process. • To work with stakeholders to gather information on needs and priorities for environmental assessment of MHK development. • To communicate research findings and directions to the MHK industry and stakeholders. • To engage in spatial planning processes in order to further the development of the MHK industry. These objectives are met through three subtasks, each of which are described in this report: • 2.1.7.1—Regulatory Assistance • 2.1.7.2—Stakeholder Outreach • 2.1.7.3—Coastal and Marine Spatial Planning As the MHK industry works with the regulatory community and stakeholders to plan, site, permit and license MHK technologies they have an interest in a predictable, efficient, and transparent process. Stakeholders and regulators have an interest in processes that result in sustainable use of ocean space with minimal effects to existing ocean users. Both stakeholders and regulators have an interest in avoiding legal challenges by meeting the intent of federal, state, and local laws that govern siting and operation of MHK technologies. The intention of work under 2.1.7 is to understand these varied interests, explore mechanisms to reduce conflict, identify efficiencies, and ultimately identify pathways to reduce the regulatory costs, time, and potential environmental impacts associated with developing, siting, permitting, and deploying MHK systems.

  7. Analysis of 217 Strains Bacteria and their Drug Susceptibility from Hospitalized Children with Lower Respiratory Tract Infections%儿童下呼吸道感染217株细菌分析及药物敏感趋势监测

    Institute of Scientific and Technical Information of China (English)

    方敏; 何邱宁

    2012-01-01

    目的:了解儿童下呼吸道感染致病菌的流行趋势和药物敏感性,为临床合理用药提供依据.方法:对2010年3月1日~2011年8月31日在我科住院的下呼吸道感染患儿痰液标本中分离出的病原菌进行药物敏感性监测分析.结果:共分离出217株病原菌.G-杆菌以大肠埃希菌(28.11%)、解鸟氨酸克雷伯菌(7.37%)、洛菲不动杆菌(6.91%)为主;G+菌以腐生葡萄球菌(9.68%)、表皮葡萄球菌(6.45%)、金黄色葡萄球菌(3.69%)为主.G-杆菌对第三代头孢菌素中的头孢他啶、头孢吡肟、氨曲南、亚胺培南、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、阿米卡星等抗生素敏感性高;G+球菌对青霉素、红霉素、克林霉素及阿奇霉素耐药率高,对其他抗生素敏感.超广谱β-内酰胺酶(ESBLs)的确证试验结果:61株大肠埃希菌产酶率55.74%;21株腐生葡萄球菌、耐甲氧西林凝固酶阴性葡萄球菌(MRSCN)产酶率9.52%,14株表皮葡萄球菌MRSCN的产酶率7.14%;5株屎肠球菌高水平氨基糖苷类耐药株( HLAR)40.00%,4株粪肠球菌HLAR为25.00%.结论:加强细菌培养和耐药性监测对临床合理使用抗生素十分必要.%Objective;To investigate the trend of lower respiratory tract infections in children and drug susceptibility to provide basis for reasonable use of drugs in clinical practice. Methods; A total of 217 strains of bacteria were isolated from sputum specimen of children who were hospitalized with lower respiratory tract infections form March 2010 to August 2011 in our hospital. The bacteria were cultured with blood dish and identified. Drug susceptibility was monitored. Results; 217 strains of bacteria were isolated. The first three places of Cram-negative bacilli were Escherichia coli (28. 11%), Klebsiella omithinolytica (7.37%) and Acinetobacter lwoffi (6.91%). The first three places of Cram-positive cocci were S. saprophyticus (9. 68% ) , S. epidermidis (6

  8. Substitution of lysine for arginine in the N-terminal 217th amino acid residue of the H gamma II of Staphylococcal gamma-hemolysin lowers the activity of the toxin.

    Science.gov (United States)

    Sudo, K; Choorit, W; Asami, I; Kaneko, J; Muramoto, K; Kamio, Y

    1995-09-01

    The staphylococcal toxin gamma-hemolysin consists of two protein components, LukF and H gamma II. Staphylococcus aureus P83 was found to have five components, LukF, LukF-PV, LukM, LukS, and H gamma II for leukocidin or gamma-hemolysin. H gamma II of S. aureus P83 was demonstrated to be a naturally-occurring analogous molecule of H gamma II [H gamma II(P83)], in which the 217th arginine residue was replaced by lysine. The H gamma II(P83) showed about 50% of the hemolytic activity of normal H gamma II in the presence of LukF.

  9. Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells.

    Science.gov (United States)

    Tripathi, Shubhandra; Srivastava, Gaurava; Sharma, Ashok

    2016-08-01

    Drug resistance poses a threatening challenge for mankind, as the development of resistance to already well-established drugs causes serious therapeutic problems. Resistance to paclitaxel (Ptxl), a complex diterpenoid working as microtubule stabilizer, is one such issue in cancer treatment. Microtubule stabilizer drugs, stabilises microtubules upon binding to β-tubulin subunit of tubulin heterodimer thus causing mitotic arrest leading to death of cancer cell. Leucine point mutations viz. L215H, L217R, and L225M were reported for Ptxl resistance in various cancers. In the current study, molecular mechanism of these resistance causing mutations was explored using molecular docking, molecular dynamics (MD) simulation, binding energy estimation (MMPBSA), free energy decomposition, principle component analysis (PCA) and free energy landscape (FEL) methods. A total of five systems including unbound βI-tubulin (Apo), docked wild+Ptxl, L215H+Ptxl, L217R+Ptxl and L225M+Ptxl were prepared, and 50 ns MD simulation was performed for each system. Binding energy estimation indicated that leucine mutation reduces the binding affinity of Ptxl in mutant types (MTs) as compared to wild type (WT). Further, in contrast to WT Ptxl interactions with the M-loop (PHE270-VAL286), S6-S7 loop and H9-H10 were significantly altered in MTs. Results showed that in MTs, Ptxl had weak interaction with M-loop residues, while having strong affinity with S6-S7 loop and H6-H7 loop. Moreover, PCA and FEL analysis revealed that M-loop flexible region (THR274-LEU284) was strongly bound with Ptxl in WT preventing its flexible movement and the causing factor for microtubule stabilization. In MTs due to poor interaction with Ptxl, M-loop flexible region retains its flexibility, therefore unable to stabilize microtubule. This study will give an insight into the importance of M-loop flexible region interaction with Ptxl for microtubule stabilization. In addition, it clearly provides the molecular basis of

  10. Comment on “Stratigraphy, petrography and dispersion of the lower Permian syn-eruptive deposits in the Viar Basin, Spain” by S. Sierra, C. Moreno and E. Pascual [Sedimentary Geology 217 (2009) 1-29

    Science.gov (United States)

    Wagner, R. H.; Mayoral, E.

    2010-07-01

    Comments are provided on a published paper on "Lower Permian" strata in SW Spain [S. Sierra, C. Moreno and E. Pascual, Stratigraphy, petrography and dispersion of the lower Permian syn-eruptive deposits in the Viar Basin, Spain, Sedimentary Geology 217 (2009) 1-29], which failed to take into account up-to-date information on this most southerly occurrence in western Europe. This generally lacustrine basin commenced with valley fill deposits in a deeply incised palaeotopography and contains mainly red beds with two basaltic intervals and a major acidic volcanic episode linked to a nearby volcanic centre to the Northeast. The stratigraphic succession shows southeasterly onlap. Although a syn-sedimentary fault has been postulated on the NE basin margin, the field evidence disproves this notion as well as the assumption that this "Early Permian" basin would have been controlled by a rejuvenated Ossa-Morena/South Portuguese boundary fault. In fact, this basin lies within the (former) area of Ossa-Morena.

  11. Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

    Directory of Open Access Journals (Sweden)

    Mary J. Eaton

    2012-01-01

    Full Text Available Effective treatment of sensory neuropathies in peripheral neuropathies and spinal cord injury (SCI is one of the most difficult problems in modern clinical practice. Cell therapy to release antinociceptive agents near the injured spinal cord is a logical next step in the development of treatment modalities. But few clinical trials, especially for chronic pain, have tested the potential of transplant of cells to treat chronic pain. Cell lines derived from the human neuronal NT2 cell line parentage, the hNT2.17 and hNT2.19 lines, which synthesize and release the neurotransmitters gamma-aminobutyric acid (GABA and serotonin (5HT, respectively, have been used to evaluate the potential of cell-based release of antinociceptive agents near the lumbar dorsal (horn spinal sensory cell centers to relieve neuropathic pain after PNS (partial nerve and diabetes-related injury and CNS (spinal cord injury damage in rat models. Both cell lines transplants potently and permanently reverse behavioral hypersensitivity without inducing tumors or other complications after grafting. Functioning as cellular minipumps for antinociception, human neuronal precursors, like these NT2-derived cell lines, would likely provide a useful adjuvant or replacement for current pharmacological treatments for neuropathic pain.

  12. Applications of composite initiator used in aqueous deposited polymerization for polyacrylonitrile%磁粉粒度对2:17型Sm-Co烧结磁体性能及微结构的影响

    Institute of Scientific and Technical Information of China (English)

    张文臣; 方以坤; 朱明刚; 赵睿; 王景代

    2011-01-01

    通过粉末冶金工艺制备了高剩磁2:17型Sm-Co永磁材料,系统地研究了磁粉平均粒度对磁体性能和微结构的影响.随着球磨时间的延长,磁粉的平均粒度D由6.2μm逐渐减小到4.3μm,烧结磁体的平均晶粒尺寸从约80μm减小到约30μm,磁体中的氧含量明显增加.当D在5.0~6.Oμm范围时,烧结磁体的综合性能较好,特别是在D=5.7μm时,磁体具有最佳的磁性能:Br=1.16T,Hcj>2069.6kA/m和(BH)m=231.6kJ/m3.%Acrylonitrile and itaconic acid copolymer, which is used in carbon fiber, was synthesized by the continuous aqueous deposited polymerization using composite redox initiator. The effect of different composite initiator, monomer ratio, polymerization temperature and initiator ratio on the copolymerization were investigated.From the results, it showed that using ammonium persulfate and ammonium sulfite to be composite initiator,the copolymerization temperature was reduced by a third when the conversion rate remains the same. The composite initiator has a positive effect on the thermal performance of polymer.

  13. 75 FR 38052 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Series Turbofan...

    Science.gov (United States)

    2010-07-01

    ... April 11, 2000 (65 FR 19477-78). Examining the AD Docket You may examine the AD docket on the Internet... 39 by superseding AD 2005-02- 03, Amendment 39-13948 (70 FR 3867, January 27, 2005). That AD requires... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3. Would not have a...

  14. 76 FR 16526 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Series Turbofan...

    Science.gov (United States)

    2011-03-24

    ...We are superseding an existing airworthiness directive (AD) for the products listed above. That AD currently requires initial and repetitive torque inspections of the 3rd stage and 4th stage low- pressure turbine (LPT) blades for shroud notch wear and replacement of the blade if wear limits are exceeded. That AD also requires replacing LPT-to-exhaust case bolts and nuts with bolts and nuts......

  15. 75 FR 50945 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2010-08-18

    ... complete Privacy Act Statement in the Federal Register published on April 11, 2000 (65 FR 19477-78...-02, Amendment 39-14242 (70 FR 52004, September 1, 2005), to require revisions to the TLS of the... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3. Would not have a...

  16. 8 CFR 217.2 - Eligibility.

    Science.gov (United States)

    2010-01-01

    ... United States from a foreign place. Designated country refers to Andorra, Australia, Austria, Belgium, Brunei, Czech Republic, Denmark, Estonia, Finland, France, Germany, Hungary, Iceland, Ireland,...

  17. 48 CFR 217.7302 - Procedures.

    Science.gov (United States)

    2010-10-01

    ... paragraph (a) of this section does not apply to contracts that are— (1) For commercial items; or (2) Valued... OF DEFENSE CONTRACTING METHODS AND CONTRACT TYPES SPECIAL CONTRACTING METHODS Identification...

  18. 22 CFR 217.3 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... part, the term: (a) The Act means the Rehabilitation Act of 1973, Pub. L. 93-112, as amended by the Rehabilitation Comprehensive Services and Developmental Disabilities Amendments of 1979, Pub. L. 95-602. (b... illness, and drug addiction and alcoholism. Such term does not include alcoholism or drug abuse, where...

  19. 22 CFR 217.14 - Preemployment inquiries.

    Science.gov (United States)

    2010-04-01

    ...) The recipient states clearly on any written questionnaire used for this purpose or makes clear orally if no written questionnaire is used that the information requested is intended for use solely...

  20. 14 CFR 16.217 - Witnesses.

    Science.gov (United States)

    2010-01-01

    ... may designate as a witness any person who is able and willing to give testimony that is relevant and... witness has no right to examine the witness or otherwise participate in the development of testimony. ... section. (b) The hearing officer may exclude testimony of witnesses that would be irrelevant,...

  1. 6 CFR 21.7 - Assurances required.

    Science.gov (United States)

    2010-01-01

    ... respect to an institution of higher education, hospital, or any other institution, insofar as the... to mortgage or otherwise encumber the real property as security for financing construction of new, or..., the Secretary may agree, upon request of the transferee and if necessary to accomplish such...

  2. 22 CFR 217.47 - Nonacademic services.

    Science.gov (United States)

    2010-04-01

    ... if no qualified handicapped student is denied the opportunity to compete for teams or to participate...) Social organizations. A recipient that provides significant assistance to fraternities, sororities, or similar organizations shall assure itself that the membership practices of such organizations do...

  3. 20 CFR 498.217 - Evidence.

    Science.gov (United States)

    2010-04-01

    ... value is substantially outweighed by the danger of unfair prejudice, confusion of the issues, or by... extent provided in Rule 408 of the Federal Rules of Evidence. (f)(1) Evidence of crimes, wrongs or acts... regardless of whether the crimes, wrongs or acts occurred during the statute of limitations period...

  4. 50 CFR 217.204 - Mitigation.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKE OF MARINE MAMMALS INCIDENTAL TO..., respectively. If a marine mammal is detected within or approaching a distance 200 m from in-water pile driving... for impact pile driving (350 m) prior to in-water impact pile driving, operations shall not...

  5. 36 CFR 21.7 - Health examinations.

    Science.gov (United States)

    2010-07-01

    ... required by the Superintendent, and being found free from any infectious or communicable disease. Cross Reference: For a list of communicable diseases included in the regulations of the United States Public Health Service, see 21 CFR 1240.54....

  6. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    International Nuclear Information System (INIS)

    A technique of selenium purification from 232Th, 238U, 226,228Ra, 227Ac and 40K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  7. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228

    Energy Technology Data Exchange (ETDEWEB)

    Aleissa, Khalid A.; Almasoud, Fahad I.; Islam, Mohammed S. [Atomic Energy Research Institute, King Abdul Aziz City for Science and Technology, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); L' Annunziata, Michael F. [IAEA Expert, Montague Group, P.O. Box 5033, Oceanside, CA 92052-5033 (United States)], E-mail: mlannunziata@cox.net

    2008-12-15

    The activities of {sup 228}Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide {sup 228}Ac. The radium was pre-concentrated on MnO{sub 2} and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter {sup 228}Ra({sup 228}Ac), the daughter nuclide {sup 228}Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by {sup 228}Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9{+-}0.1% was measured for {sup 228}Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317{+-}0.013 cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1 g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of {sup 228}Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for {sup 228}Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure {sup 228}Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  8. Radium-228 analysis of natural waters by Cherenkov counting of Actinium-228.

    Science.gov (United States)

    Aleissa, Khalid A; Almasoud, Fahad I; Islam, Mohammed S; L'Annunziata, Michael F

    2008-12-01

    The activities of (228)Ra in natural waters were determined by the Cherenkov counting of the daughter nuclide (228)Ac. The radium was pre-concentrated on MnO(2) and the radium purified via ion exchange and, after a 2-day period of incubation to allow for secular equilibrium between the parent-daughter (228)Ra((228)Ac), the daughter nuclide (228)Ac was isolated by ion exchange according to the method of Nour et al. [2004. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin. Appl. Radiat. Isot. 61, 1173-1178]. The Cherenkov photons produced by (228)Ac were counted directly without the addition of any scintillation reagents. The optimum Cherenkov counting window, sample volume, and vial type were determined experimentally to achieve optimum Cherenkov photon detection efficiency and lowest background count rates. An optimum detection efficiency of 10.9+/-0.1% was measured for (228)Ac by Cherenkov counting with a very low Cherenkov photon background of 0.317+/-0.013cpm. The addition of sodium salicylate into the sample counting vial at a concentration of 0.1g/mL yielded a more than 3-fold increase in the Cherenkov detection efficiency of (228)Ac to 38%. Tests of the Cherenkov counting technique were conducted with several water standards of known activity and the results obtained compared closely with a conventional liquid scintillation counting technique. The advantages and disadvantages of Cherenkov counting compared to liquid scintillation counting methods are discussed. Advantages include much lower Cherenkov background count rates and consequently lower minimal detectable activities for (228)Ra and no need for expensive environmentally unfriendly liquid scintillation cocktails. The disadvantages of the Cherenkov counting method include the need to measure (228)Ac Cherenkov photon detection efficiency and optimum Cherenkov counting volume, which are not at all required when liquid scintillation analysis is used.

  9. Purification of selenium from thorium, uranium, radium, actinium and potassium impurities for low background measurements

    Energy Technology Data Exchange (ETDEWEB)

    Rakhimov, A.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz); Warot, G. [CEA-CNRS, Modane (France). Laboratoire Souterrain de Modane (LSM); Karaivanov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Institute for Nuclear Research and Nuclear Energy (INRNE), Sofia (Bulgaria); Kochetov, O.I.; Lebedev, N.A.; Filosofov, D.V. [Joint Institute for Nuclear Research (JINR), Dubna (Russian Federation); Mukhamedshina, N.M.; Sadikov, I.I. [Uzbek Academy of Sciences, Tashkent (Uzbekistan). Inst. of Nuclear Physics (INP AS RUz)

    2013-07-01

    A technique of selenium purification from {sup 232}Th, {sup 238}U, {sup 226,228}Ra, {sup 227}Ac and {sup 40}K was developed. This technique is simple to perform and employs a minimum number of highly pure reagents (bidistilled water, nitric acid). Operations carried out during purification (elution, evaporation) practically exclude losses of the target product (chemical yields of Se > 99%). A test purification of 100 g of selenium was carried out using this technique. The efficiency of this technique was confirmed by low background gamma spectrometry of the purified selenium sample. Distribution coefficients of Th, U, Ra and Ac on DOWEX 50W- x 8 cation-exchange resin at different concentrations of selenium and nitric acid were experimentally determinated. Instrumental neutron activation analysis of bidistilled water, deionized water and nitric acid was performed. (orig.)

  10. Linear free energy relationship applied to trivalent cations with lanthanum and actinium oxide and hydroxide structure

    International Nuclear Information System (INIS)

    Linear free energy relationships for trivalent cations with crystalline M2O3 and, M(OH)3 phases of lanthanides and actinides were developed from known thermodynamic properties of the aqueous trivalent cations, modifying the Sverjensky and Molling equation. The linear free energy relationship for trivalent cations is as ΔGf,MvX0=aMvXΔGn,M3+0+bMvX+βMvXrM3+, where the coefficients aMvX, bMvX, and βMvX characterize a particular structural family of MvX, rM3+ is the ionic radius of M3+ cation, ΔGf,MvX0 is the standard Gibbs free energy of formation of MvX and ΔGn,M3+0 is the standard non-solvation free energy of the cation. The coefficients for the oxide family are: aMvX=0.2705, bMvX=-1984.75 (kJ/mol), and βMvX=197.24 (kJ/molnm). The coefficients for the hydroxide family are: aMvX=0.1587, bMvX=-1474.09 (kJ/mol), and βMvX=791.70 (kJ/molnm).

  11. Actinium: A RESTful Runtime Container for Scriptable Internet of Things Applications

    OpenAIRE

    Kovatsch, Matthias; Lanter, Martin; Duquennoy, Simon

    2012-01-01

    Programming Internet of Things (IoT) applications is challenging because developers have to be knowledgeable in various technical domains, from low-power networking, over embedded operating systems, to distributed algorithms. Hence, it will be challenging to find enough experts to provide software for the vast number of expected devices, which must also be scalable and particularly safe due to the connection to the physical world. To remedy this situation, we propose an architecture that pr...

  12. Reflection asymmetry in odd-A and odd-odd actinium nuclei

    International Nuclear Information System (INIS)

    Theoretical calculations and measurements indicate that octupole correlations are at a maximum in the ground states of the odd-proton nuclei Ac and Pa. It has been expected that odd-odd nuclei should have even larger amount of octupole-octupole correlations. We have recently made measurements on the structure of 224Ac. Although spin and parity assignments could not be made, two bands starting at 354.1 and 360.0 keV have properties characteristic of reflection asymmetric shape. These two bands have very similar rotational constants and also similar alpha decay rates, which suggest similarity between the wavefunctions of these bands. These signatures provide evidence for octupole correlations in these nuclides

  13. Bestimmung der Ionisationsenergie von Actinium und Ultraspurenanalyse von Plutonium mit resonanter Ionisationsmassenspektrometrie (RIMS)

    OpenAIRE

    Waldek, Achim Marcus

    2001-01-01

    ZusammenfassungDie Resonanzionisationsmassenspektrometrie (RIMS) verbindet hohe Elementselektivität mit guter Nachweiseffizienz. Aufgrund dieser Eigenschaften ist die Methode für Ultraspurenanalyse und Untersuchungen an seltenen oder schwer handhabbaren Elementen gut geeignet. Für RIMS werden neutrale Atome mit monochromatischem Laserlicht ein- oder mehrfach resonant auf energetisch hoch liegende Niveaus angeregt und anschließend durch einen weiteren Laserstrahl oder durch ein elektrisches Fe...

  14. New method for large scale production of medically applicable Actinium-225 and Radium-223

    International Nuclear Information System (INIS)

    Alpha-emitters (211At, 212Bi, 213Bi, 223Ra, 225Ac) are promising for targeted radiotherapy of cancer. Only two alpha decays near a cell membrane result in 50% death of cancer cell and only a single decay inside the cell is required for this. 225Ac may be used either directly or as a mother radionuclide in 213Bi isotope generator. Production of 225Ac is provided by three main suppliers - Institute for Transuranium Elements in Germany, Oak Ridge National Laboratory in USA and Institute of Physics and Power Engineering in Obninsk, Russia. The current worldwide production of 225Ac is approximately 1.7 Ci per year that corresponds to only 100-200 patients that could be treated annually. The common approach for 225Ac production is separation from mother 229Th or irradiation of 226Ra with protons in a cyclotron. Both the methods have some practical limitations to be applied routinely. 225Ac can be also produced by irradiation of natural thorium with medium energy protons . Cumulative cross sections of 225Ac, 227Ac, 227Th, 228Th formations have been obtained recently. Thorium targets (1-9 g) were irradiated by 114-91 MeV proton beam (1-50 μA) at INR linear accelerator. After dissolution in 8 M HNO3 + 0.004 M HF thorium was removed by double LLX by HDEHP in toluene (1:1). Ac and REE were pre-concentrated and separated from Ra and most fission products by DGA-Resin (Triskem). After washing out by 0.01 M HNO3 Ac was separated from REE by TRU Resin (Triskem) in 3 M HNO3 media. About 6 mCi 225Ac were separated in hot cell with chemical yield 85%. The method may be upscaled for production of Ci amounts of the radionuclide. The main impurity is 227Ac (0.1% at the EOB) but it does not hinder 225Ac from being used for medical 225Ac/213Bi generators. (author)

  15. Triple water vapor isotopic (H218O, HD16O, H217O) measurements above the Greenland Ice Sheet and importance for understanding the atmospheric hydrological cycle in the Arctic

    Science.gov (United States)

    Steen-Larsen, H.; Winkler, R.; Prie, F.; Landais, A.; Masson-Delmotte, V.; Risi, C.; Berkelhammer, M. B.; Noone, D. C.; O'Neill, M.; Guillevic, M.; Hirabayashi, M.; Schneider, D. P.; Stenni, B.

    2012-12-01

    Novel triple water stable isotope measurements (H_2^{18}O, HD^{16}O, H_2^{17}O) revealing both d-excess and ^{17}O-excess have been carried out on both vapor and snow samples with the aim at improving our understanding of the atmospheric processes affecting ice core isotopic records. This has shed new light on both the super saturation during snow crystal formation and source region conditions [e.g. Landais et al. 2012; 2008, Winkler et al. 2012, Uemura et al. 2010]. We have for the last four summer seasons since 2009 measured the isotopic composition of the water vapor in continuous mode on top of the Greenland Ice Sheet as part of the NEEM deep ice core-drilling project (77.45 N 51.06 W, 2484 m a.s.l). Furthermore, during the 2012 summer campaign we carried out continuous isotopic water vapor measurements in tandem at two sites on top of the Greenland Ice sheet: at both Summit station (72.50 N 38.50 W, 3250 m a.s.l) and NEEM station. By comparing the observed variability of the in-situ water vapor isotopic composition with isotope-enabled general circulation models we have been able to both validate and point to weaknesses in the modeled isotopic values. We find that the general circulation model (LMDZiso) used here reasonably captures both variations in absolute humidity and vapor isotope composition. However comparing the observed and modeled d-excess reveals a very poor correlation. We understand this as indications for the general circulation model (LMDZiso) having a correct representation of the large-scale atmospheric circulation but having poor sub-grid physics performance especially related to the simulation of relative humidity in the Arctic Ocean boundary layer. We use back trajectory analysis to relate the origin of the water vapor to its isotopic fingerprint, in particular for the d-excess and ^{17}O-excess. This leads us to identify Arctic and North Atlantic origin respectively. By combining the d-excess and ^{17}O-excess we are able to show the

  16. 49 CFR 571.217 - Standard No. 217; Bus emergency exits and window retention and release.

    Science.gov (United States)

    2010-10-01

    ... exits and window retention and release. S1. Scope. This standard establishes requirements for the... egress. S3. Application. This standard applies to buses, except buses manufactured for the purpose of transporting persons under physical restraint. S4. Definitions. Adjacent seat means a designated...

  17. Synthesis and identification of 2-(2-hydroxyethoxy)-17β-hydroxy-2,17α-dimethyl-A-nor-5α-androstane,a by-product of oxandrolone during its synthesis%氧甲氢龙合成中伴生副产物2-(2-羟基乙氧基)-17β-羟基-2,17α-二甲基-A-失碳-5α-雄甾烷的鉴定与合成

    Institute of Scientific and Technical Information of China (English)

    屈洁; 饶志威; 左文果; 赵徐波; 李宗桃

    2012-01-01

    目的 为改进氧甲氢龙的合成工艺及提高产率提供实验依据.方法 通过柱色谱、重结晶等方法分离纯化合成氧甲氢龙过程中发现的副产物,经IR、1H-NMR、3C-NMR、MS、元素分析、X-单晶衍射实验等分析手段确证副产物的化学结构;推测副产物的形成机制并按此机制合成该副产物.结果与结论 鉴定副产物为2-(2-羟基乙氧基)-17β-羟基-2,17α-二甲基-A-失碳-Sα-雄甾烷,其形成机制可能是格氏试剂形成的甲基负离子在进攻中间体(7)17位的羰基碳的同时,一部分的甲基负离子从甾体平面结构的下方进攻了2位的乙缩酮的碳原子进而生成该副产物.准确分析出副产物的化学结构及形成机制.%Oxandrolone is an anabolic hormone drug and has strong anabolic effect with no obvious andro-genic effect. In synthesizing 2,2-ethandiyldioxy-17α-methyl-A-nor-5α-androstan-17β-ol which is one of the important intermediate of oxandrolone, a by-product was separated by column chromatography. The chemical structure of this by-product was confirmed as 2-(2-hydroxyethoxy)-17β-hydroxy-2,17αdirnethyl-A-nor-5α-androstane by melting point,IR,1H-NMR,13C-NMR,MS,and elemental analysis. Then the by-product was synthesized in order to study its possible formation mechanism. The result showed that the ketal structure is cleavaged in the presence of excessive methylmagnesium iodide that attacked 2-carbon when the methylmag-nesium iodide attacked 17-carbon.

  18. Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy; Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie

    Energy Technology Data Exchange (ETDEWEB)

    Marx, Sebastian Markus

    2014-09-23

    The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.

  19. Renal uptake of bismuth-213 and its contribution to kidney radiation dose following administration of actinium-225-labeled antibody

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, J; O' Donoghue, J A; Humm, J L [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); Jaggi, J S [Bristol-Myers Squibb, Plainsboro, NJ (United States); Ruan, S; Larson, S M [Nuclear Medicine Service Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 (United States); McDevitt, M; Scheinberg, D A, E-mail: schwarj1@mskcc.org [Molecular Pharmacology and Chemistry, Sloan-Kettering Institute, 1275 York Avenue, New York, NY 10065 (United States)

    2011-02-07

    Clinical therapeutic studies using {sup 225}Ac-labeled antibodies have begun. Of major concern is renal toxicity that may result from the three alpha-emitting progeny generated following the decay of {sup 225}Ac. The purpose of this study was to determine the amount of {sup 225}Ac and non-equilibrium progeny in the mouse kidney after the injection of {sup 225}Ac-huM195 antibody and examine the dosimetric consequences. Groups of mice were sacrificed at 24, 96 and 144 h after injection with {sup 225}Ac-huM195 antibody and kidneys excised. One kidney was used for gamma ray spectroscopic measurements by a high-purity germanium (HPGe) detector. The second kidney was used to generate frozen tissue sections which were examined by digital autoradiography (DAR). Two measurements were performed on each kidney specimen: (1) immediately post-resection and (2) after sufficient time for any non-equilibrium excess {sup 213}Bi to decay completely. Comparison of these measurements enabled estimation of the amount of excess {sup 213}Bi reaching the kidney ({gamma}-ray spectroscopy) and its sub-regional distribution (DAR). The average absorbed dose to whole kidney, determined by spectroscopy, was 0.77 (SD 0.21) Gy kBq{sup -1}, of which 0.46 (SD 0.16) Gy kBq{sup -1} (i.e. 60%) was due to non-equilibrium excess {sup 213}Bi. The relative contributions to renal cortex and medulla were determined by DAR. The estimated dose to the cortex from non-equilibrium excess {sup 213}Bi (0.31 (SD 0.11) Gy kBq{sup -1}) represented {approx}46% of the total. For the medulla the dose contribution from excess {sup 213}Bi (0.81 (SD 0.28) Gy kBq{sup -1}) was {approx}80% of the total. Based on these estimates, for human patients we project a kidney-absorbed dose of 0.28 Gy MBq{sup -1} following administration of {sup 225}Ac-huM195 with non-equilibrium excess {sup 213}Bi responsible for approximately 60% of the total. Methods to reduce renal accumulation of radioactive progeny appear to be necessary for the success of {sup 225}Ac radioimmunotherapy.

  20. Production of actinium, thorium and radium isotopes from natural thorium irradiated with protons up to 141 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Ermolaev, S.V.; Zhuikov, B.L.; Kokhanyuk, V.M.; Matushko, V.L. [Russian Academy of Sciences, Moscow (Russian Federation). Inst. of Nuclear Research; Kalmykov, S.N. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Chemistry Dept.; Aliev, R.A. [Lomonosov Moscow State Univ., Moscow (Russian Federation). Skobeltsyn Inst. of Nuclear Physics; Tananaev, I.G.; Myasoedov, B.F. [Russian Academy of Sciences, Moscow (Russian Federation). A.N. Frumkin Inst. of Physical Chemistry and Electrochemistry

    2012-07-01

    Cross sections of {sup 225}Ac, {sup 227}Ac, {sup 227}Th and {sup 228}Th in thorium-232 targets irradiated with protons in the energy range 21-141 MeV have been measured. Based on these data, production yields of {sup 225}Ac and {sup 223}Ra in thick thorium targets have been calculated. It is possible to produce in proton energy range 60-140 MeV about 96 GBq (2.6 Ci) {sup 225}Ac per 10-d irradiation with 100 {mu}A proton beam current and 10-d decay, and much higher amount of {sup 223}Ra. The impurities of {sup 227}Ac and {sup 224}Ra are important and need to be assessed for further medical applications. (orig.)

  1. Big Desire Equal to No Desire:Chuang-tzu's Thoughts in Passage 217 of Tsurezuregus%《徒然草》第二百十七段中的《庄子》思想——以“大欲与无欲相似”为视点

    Institute of Scientific and Technical Information of China (English)

    陈秉珊

    2012-01-01

    The process of a rich man's acquisition of wealth is narrated in Passage 217 of Tsurezuregus. According to the millionaire, accumulation of wealth is the most important thing in one's life, and one should practice spiritual asceticism for the good of one's wealth. Anyhow, this point of view is opposed by Kenk6, who insists that a big amount of wealth accumulated by suppressing one's desire is nothing better than no wealth at all ;therefore, wealth is nothing better than poverty in the rich man's case. The author of this article believes that Kenk's comment on wealth and desire has relevance to the thoughts in Chuang-tzu.%《徒然草》第二百十七段中某大富翁认为,人生最重要的就是不断积累财富,为积蓄财富,就要禁锢一切欲望,进行精神上的修行。对此,兼好提出异议,认为通过禁止任何欲望积累钱财,还不如一开始就没有钱财的好。按大富翁的逻辑,贫富将无区别,大欲与无欲相似。该段与《庄子》思想有较强的关联性。

  2. Alkaline earth-gold-aluminides. Synthesis and structure of SrAu{sub 3}Al{sub 2}, SrAu{sub 2.83}Al{sub 2.17}, BaAu{sub 2.89}Al{sub 2.11} and BaAu{sub 7.09}Al{sub 5.91}

    Energy Technology Data Exchange (ETDEWEB)

    Gerke, Birgit; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie

    2015-07-01

    New alkaline earth-gold-aluminides were synthesized from the elements in sealed tantalum or quartz ampoules in muffle furnaces at maximum annealing temperatures of 1325 K. The structures were refined from single crystal X-ray diffractometer data. SrAu{sub 3}Al{sub 2} crystallizes in an ordered version of the LT-SrZn{sub 5} structure: Pnma, a = 1315.9(3), b = 549.0(1), c = 684.5(3) pm, wR2 = 0.0232, 930 F{sup 2} values, 35 variables. SrAu{sub 2.83}Al{sub 2.17} (a = 1065.0(2), b = 845.0(2), c = 548.1(1) pm, wR2 = 0.0416, 452 F{sup 2} values, 22 variables) and BaAu{sub 2.89}Al{sub 2.11} (a = 1096.1(3), b = 835.7(3), c = 554.0(1) pm, wR2 = 0.0280, 501 F{sup 2} values, 22 variables) both adopt the BaZn{sub 5} type, space group Cmcm with Au/Al mixing on the 4c site. The gold and aluminum atoms in both types form three-dimensional networks of condensed tetrahedra with the strontium and barium atoms in large cavities. BaAu{sub 7.09}Al{sub 5.91} is a new member of the NaZn{sub 13} type: Fm anti 3c, a = 1257.6(2) pm, wR2 = 0.0267, 168 F{sup 2} values, 12 variables. Both the 96i and 8b sites show Au/Al mixing. The crystal chemical details are discussed.

  3. 48 CFR 3052.217-95 - Liability and insurance (USCG).

    Science.gov (United States)

    2010-10-01

    ... in USCG guidance at (HSAR) 48 CFR 3017.9000(a) and (b), insert the following clause: Liability and... vessel or its owner, arising in whole or in part from the negligence or other wrongful act of the... Officer may, without prejudice to any right of the Government, either— (1) Order the Contractor to...

  4. 50 CFR 216.217 - Requirements for monitoring and reporting.

    Science.gov (United States)

    2010-10-01

    ..., and any other Federal, state or local agency with regulatory authority over the offshore oil-and-gas...) Acoustic surveys will be run concurrent with requisite pre-detonation surveys, beginning with the surface observations and concluding at the finish of the aerial surveys when the detonation(s) is allowed to...

  5. 34 CFR 685.217 - Teacher loan forgiveness program.

    Science.gov (United States)

    2010-07-01

    ... teacher for five consecutive complete academic years. The required five years of teaching may include any... as a teacher. For a borrower teaching in more than one school, the determination of full-time is... borrower— (A) Demonstrated knowledge and teaching skills in reading, writing, mathematics, and other...

  6. Dicty_cDB: SHH217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 16 3 BM056853 |BM056853.1 2154-85 hindgut and Malpighian tubule subtracted cDNA library Ctenocephalides feli...9 hindgut and Malpighian tubule subtracted cDNA library Ctenocephalides felis cDN...2018A03 5', mRNA sequence. 88 6e-14 2 BM058578 |BM058578.1 2193-94 hindgut and Malpighian tubule subtracted cDNA library Ctenocephali...des felis cDNA clone 2193-94, mRNA sequence. 90 1e-13 1 BM058379 |BM058379.1 2191-2

  7. 1935 15' Quad #217 Aerial Photo Mosaic Index - AZ

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  8. 22 CFR 217.42 - Admissions and recruitment.

    Science.gov (United States)

    2010-04-01

    ... those skills are the factors that the test purports to measure); (ii) admissions tests that are designed... written questionnaire used for this purpose or makes clear orally if no written questionnaire is used...

  9. Dicty_cDB: VSF217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available GWEMPVQYPAGVMKEHLHV RKESGLFDVSHMGQLRIHGKDRVKFFESIVVADLQALPTGHSKLSVFTNEKGGIIDDTMI TNAGDSLYVVVNAGCADKDISHINE...HLHV RKESGLFDVSHMGQLRIHGKDRVKFFESIVVADLQALPTGHSKLSVFTNEKGGIIDDTMI TNAGDSLYVVVNAGCADKDISHINEKIKEFKSVNPTHDVSMQ

  10. 78 FR 217 - Shared Responsibility for Employers Regarding Health Coverage

    Science.gov (United States)

    2013-01-02

    ... meet the definition of ``applicable large employer'' as described in these proposed regulations. As...: Background This document contains proposed Pension Excise Tax Regulations (26 CFR part 54) under section... employer as having received an applicable premium tax credit or cost- sharing reduction (section...

  11. 48 CFR 217.208-70 - Additional clauses.

    Science.gov (United States)

    2010-10-01

    ... Foreign Military Sales Commitments, when an option may be used for foreign military sale requirements. (1) Use Alternate I when the foreign military sale country is not known at the time of solicitation or... stocks, or acquisitions made under DoD cooperative logistics support arrangements. (b) When a...

  12. 48 CFR 252.217-7027 - Contract definitization.

    Science.gov (United States)

    2010-10-01

    ... required by law on the date of execution of the definitive contract action, and (3) any other mutually... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Contract definitization... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES...

  13. Dicty_cDB: CHD217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available isozyme 3 mRNA, complete cds. 58 2e-07 2 CK273593 |CK273593.1 EST719671 potato abiotic stress cDNA library ... An expressed sequence tag database for abiotic stressed leaves of Vitis vinifera...6D06_332552 An expressed sequence tag database for abiotic stressed leaves of Vitis vinifera var. Chardonnay...214.1 VVB158G03_410335 An expressed sequence tag database for abiotic stressed leaves of Vitis vinifera var.

  14. Dicty_cDB: VHN217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 25 ) Dictyostelium discoideum cDNA clone:ddv50l04, 3' ... 1094 0.0 3 ( BJ442653 )... Dictyostelium discoideum cDNA clone:ddv50f18, 3' ... 1076 0.0 4 ( BJ445359 ) Dictyostelium discoideum cDNA ...clone:ddv59a09, 3' ... 1007 0.0 3 ( BJ442499 ) Dictyostelium discoideum cDNA clone:ddv50g01, 3' ... 999 0.0

  15. Dicty_cDB: VHF217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Dictyostelium discoideum cDNA clone:ddv50j21, 5' ... 100 3e-17 1 ( BJ423810 ) Di...ctyostelium discoideum cDNA clone:ddv50a16, 5' ... 100 3e-17 1 ( BJ423633 ) Dictyostelium discoideum cDNA cl

  16. Dicty_cDB: VHO217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CF828602 |CF828602.1 UCRCR01_01N10_r Clementine Mandarin Albedo at Rind Separation cDNA Library Citrus retic...R01_01H10_r Clementine Mandarin Albedo at Rind Separation cDNA Library Citrus reticulata cDNA clone CR_CEa01...28476.1 UCRCR01_01K07_r Clementine Mandarin Albedo at Rind Separation cDNA Library Citrus reticulata cDNA cl

  17. 50 CFR 217.205 - Requirements for monitoring and reporting.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKE OF MARINE... monitoring at the Port of Anchorage beginning 30 minutes prior to and during all in-water pile driving or... composition, initial and closest distance to pile driving hammer, and behavior (e.g., activity,...

  18. 48 CFR 217.172 - Multiyear contracts for supplies.

    Science.gov (United States)

    2010-10-01

    ... the agency shall submit to USD(C)(P/B) information supporting the agency's determination that this... supporting this certification to USD(C)(P/B) for transmission to Congress through the Secretary of...

  19. Dicty_cDB: CHS217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available DYQCLLWCPPKYAALMNRCWETDPTHRPSFPEILPNYGGNDL*iskreeginsar *tntlcwpt*krsiq*ttttkygxnnsttigttttstiirttntptsxttss...f aqkeldtkkrkkeesr*f*KTTYLKTELKIETTLXRNCKLQMPRQPKFE--- ---VKDYQCLLWCPPKYAALMNRCWETDPTHRPSFPEILPNYGGNDL*iskreeginsar

  20. 29 CFR 1910.217 - Mechanical power presses.

    Science.gov (United States)

    2010-07-01

    ... (establishment). (ii) Employee's name, injury sustained, and the task being performed (operation, set-up...) Where brake engagement and clutch release is effected by spring action, such spring(s) shall operate...

  1. Dicty_cDB: AFL217 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ranslated Amino Acid sequence llyky*ihilffyil*HFIKKKKKKKXKKXPFLKKK--- ---NVKPXFQDKGGFPPXQXRFISXVXN*xmxxlslipiskknxls...- ---NVKPXFQDKGGFPPXQXRFISXVXN*xmxxlslipiskknxlshlvxrlrggmqifv ktltgktitlevegsdnienvktkiqdkegippdqqrlifagkql

  2. 75 FR 12968 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2010-03-18

    ... (62 FR 4902). ADDRESSES: You can get the service information identified in this AD from Pratt... proposed AD in the Federal Register on December 21, 2009 (74 FR 67831). That action proposed to require...'' under DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and (3) Will not have...

  3. Laboratory manual for salt-mixing test in 37- and 217-pin bundles

    International Nuclear Information System (INIS)

    This laboratory manual deals with the procedure employed during salt tracer experiments used in evaluating the hydraulic characteristics of a rod bundle. A description of the standard equipment used is given together with the details of manufacture of probes used for detecting the salt concentration. Details of the bundle construction have been excluded as they are availble in the reference cited. An attempt has been made to point out potential trouble areas and procedures

  4. People and things. CERN Courier, September 1981, v. 21(7)

    International Nuclear Information System (INIS)

    The article reports on achievements of various people, staff changes and position opportunities within the CERN organization and contains news updates on upcoming or past events: The King of Belgium recently paid a state visit to the People's Republic of China and invited four Belgian scientists to accompany him — M. Engelborghs-Bertelsr P. Melchior (Royal Observatory of Brussels and Louvain), J. van der Veken (Louvain) and Y. Go/dschmidt-Clermont (Brussels and CERN). Yves Goldschmidt- Clermont provided us with the following report. Italian physicists are presently developing a large modular track detector to be installed in the future Gran Sasso underground laboratory. Such a 'Giant Underground track- Detector' (GUD), up to 10 Kt in mass, should be capable of investigating nucleon decay and the interactions of high energy cosmic neutrinos. An International Conference on Nucleus-Nucleus Collisions will be held at Michigan State University from 26 September to 1 October, 1982

  5. 48 CFR 252.217-7005 - Inspection and manner of doing work.

    Science.gov (United States)

    2010-10-01

    ... Shipping, the U.S. Coast Guard, and the Institute of Electrical and Electronic Engineers, in effect at the... accordance with Occupational Safety and Health Administration regulations (29 CFR 1915.14) before any hot... shall at all times keep the site of the work on the vessel free from accumulation of waste material...

  6. Q/SdR.04.896-2008 SQR7130A217/Model A Car

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    1.Background As the development of global economy demands an increasingly large quantity of energy,the energy crisis is getting more severe.Auto manufacturers in Japan,America,and Europe have all began to develop hybrid power vehicles or its technology platform since 1990s,so as to save energy.Relied on its THS system which consists of the planet wheel and e-CVT,TOYOTA developed a series of strong hybrid power vehicles,such as Prius,Lexus,Highlander,Camry,etc.Based on its IMA system,HONDA developed a series of mild hybrid power vehicles,such as Insight,Civic,Accord,etc.On the basis of its Belt-driven Starter Generator (BSG) system,French SPA Group developed a series of weak hybrid power vehicles,such as Citroen C3,Citroen C2,Citroen 1007,Citroen 207,etc.In America the research of hybrid power vehicle is being done actively by a group of relevant parties consisting of Department of Transport,Department of Defense,major auto companies and relevant organizations under the leadership of Department of Energy and with the large quantity ofinvestment from GE Motors Co.and CHRYSLER.

  7. Progress of Recycling in the Built Environment Final report of the RILEM Technical Committee 217-PRE

    CERN Document Server

    2013-01-01

    This report is a useful tool for countries starting to recycle aggregates or construction and demolition waste. It contains the latest developments in this field, introduces a completely new approach to the procedure of proportioning concrete mixtures with recycled aggregate, references recent publications, opinions and discrepancies in relation to the durability of recycled concrete, such as freeze-thaw standards, studies of chloride penetration and diffusion, and sulfate attacks, the use of the fine fraction <4mm, quality assurance of concrete recycled aggregate, sustainability and recycling construction waste and global impact assessment of urban renewal based on sustainable recycling strategies for construction and demolition waste. This volume will be of interest to recyclers, researchers and consumers.

  8. Laboratory manual for salt-mixing test in 37- and 217-pin bundles. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Chan, Y.N.; Todreas, N.E.

    1980-08-01

    This laboratory manual deals with the procedure employed during salt tracer experiments used in evaluating the hydraulic characteristics of a rod bundle. A description of the standard equipment used is given together with the details of manufacture of probes used for detecting the salt concentration. Details of the bundle construction have been excluded as they are availble in the reference cited. An attempt has been made to point out potential trouble areas and procedures.

  9. 25 CFR 39.217 - How are students counted for the purpose of funding residential services?

    Science.gov (United States)

    2010-04-01

    ...) Present for both the after school count and the midnight count at least one night during each week... EDUCATION THE INDIAN SCHOOL EQUALIZATION PROGRAM Administrative Procedures, Student Counts, and... services? For a student to be considered in residence for purposes of this subpart, the school must be...

  10. SU-E-T-217: Intrinsic Respiratory Gating in Small Animal CT

    International Nuclear Information System (INIS)

    Purpose: Preclinical animal models of lung cancer can provide a controlled test-bed for testing dose escalation or function-based-treatment-planning studies. However, to extract lung function, i.e. ventilation, one needs to be able to image the lung at different phases of ventilation (in-hale / ex-hale). Most respiratory-gated imaging using micro-CT involves using an external ventilator and surgical intervention limiting the utility in longitudinal studies. A new intrinsic respiratory retrospective gating method was developed and tested in mice. Methods: A fixed region of interest (ROI) that covers the diaphragm was selected on all projection images to estimate the mean intensity (M). The mean intensity depends on the projection angle and diaphragm position. A 3-point moving average (A) of consecutive M values: Mpre, Mcurrent and Mpost, was calculated to be subtracted from Mcurrent. A fixed threshold was used to enable amplitude based sorting into 4 different phases of respiration. Images at full-inhale and end-exhale phases of respiration were reconstructed using the open source OSCaR. Lung volumes estimated at the 2 phases of respiration were validated against literature values. Results: Intrinsic retrospective gating was accomplished without the use of any external breathing waveform. While projection images were acquired at 360 different angles. Only 138 and 104 projections were used to reconstruct images at full-inhale and end-exhale. This often results in non-uniform under-sampled angular projections leading to some minor streaking artifacts. The calculated expiratory, inspiratory and tidal lung volumes correlated well with the values known from the literature. Conclusion: Our initial result demonstrates an intrinsic gating method that is suitable for flat panel cone beam small animal CT systems. Reduction in streaking artifacts can be accomplished by oversampling the data or using iterative reconstruction methods. This initial experience will enable freebreathing small animal micro-CT imaging to fuel longitudinal studies of lung function

  11. SU-E-T-217: Intrinsic Respiratory Gating in Small Animal CT

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Y; Smith, M; Mistry, N [University of Maryland School of Medicine, Baltimore, MD (United States)

    2014-06-01

    Purpose: Preclinical animal models of lung cancer can provide a controlled test-bed for testing dose escalation or function-based-treatment-planning studies. However, to extract lung function, i.e. ventilation, one needs to be able to image the lung at different phases of ventilation (in-hale / ex-hale). Most respiratory-gated imaging using micro-CT involves using an external ventilator and surgical intervention limiting the utility in longitudinal studies. A new intrinsic respiratory retrospective gating method was developed and tested in mice. Methods: A fixed region of interest (ROI) that covers the diaphragm was selected on all projection images to estimate the mean intensity (M). The mean intensity depends on the projection angle and diaphragm position. A 3-point moving average (A) of consecutive M values: Mpre, Mcurrent and Mpost, was calculated to be subtracted from Mcurrent. A fixed threshold was used to enable amplitude based sorting into 4 different phases of respiration. Images at full-inhale and end-exhale phases of respiration were reconstructed using the open source OSCaR. Lung volumes estimated at the 2 phases of respiration were validated against literature values. Results: Intrinsic retrospective gating was accomplished without the use of any external breathing waveform. While projection images were acquired at 360 different angles. Only 138 and 104 projections were used to reconstruct images at full-inhale and end-exhale. This often results in non-uniform under-sampled angular projections leading to some minor streaking artifacts. The calculated expiratory, inspiratory and tidal lung volumes correlated well with the values known from the literature. Conclusion: Our initial result demonstrates an intrinsic gating method that is suitable for flat panel cone beam small animal CT systems. Reduction in streaking artifacts can be accomplished by oversampling the data or using iterative reconstruction methods. This initial experience will enable freebreathing small animal micro-CT imaging to fuel longitudinal studies of lung function.

  12. A 217-year record of summer air temperature reconstructed from freshwater pearl mussels ( M. margarifitera, Sweden)

    Science.gov (United States)

    Schöne, Bernd R.; Dunca, Elena; Mutvei, Harry; Norlund, Ulf

    2004-09-01

    Variations in annual shell growth of the freshwater pearl mussel Margritifera margritifera (L.) were utilized to reconstruct summer (June-August) air temperatures for each year over the period AD 1777-1993. Our study is based on 60 live-collected specimens with overlapping life-spans from six different Swedish rivers. Individual age-detrended and standardized chronologies ranging from 10 to 127 years in length were strung together to form one master chronology (AD 1777-1993) and three regional mean chronologies (Stensele, Uppsala, and Karlshamn). Standardized annual growth rates and air temperature (river water covaries with water temperature) exhibit a significant positive correlation and high running similarity confirming previous experimental findings. Up to 55% in the variability of annual shell growth is explained by temperature changes. From north to south this correlation slightly decreases. We establish a growth-temperature model capable of reconstructing summer air temperature from annual shell growth increments with a precision error of ±0.6-0.9°C (2SD). The validity of the model was tested against instrumentally determined air temperatures and proxy temperatures derived from tree rings. Our study demonstrates that freshwater pearl mussels provide an independent measure for past (i.e., prior to the 20th century greenhouse forcing) changes in air temperature. It can be used to test and verify other air temperature proxies and thus improve climate models.

  13. 49 CFR 232.217 - Train brake tests conducted using yard air.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Train brake tests conducted using yard air. 232... Train brake tests conducted using yard air. (a) When a train air brake system is tested from a yard air... reduction of brake pipe air pressure at the same, or slower, rate as an engineer's brake valve. (b) The...

  14. 5 CFR 591.217 - In which outlets does OPM collect prices?

    Science.gov (United States)

    2010-01-01

    ... data collection areas, accessibility by road, physical size, advertising, and other characteristics that reflect sales volume. To the extent practical, OPM prices like items in the same types of...

  15. Yeast Interacting Proteins Database: YMR159C, YBR217W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form ...d in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg1

  16. Yeast Interacting Proteins Database: YPL149W, YBR217W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available conjugation with Atg12p to form a complex involved in Atg8p lipidation; conjugated Atg12p also forms a comp...ophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p... Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; conjugated A...olved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation;

  17. 48 CFR 1252.217-73 - Inspection and manner of doing work.

    Science.gov (United States)

    2010-10-01

    ... work in accordance with the contract, any drawings and specifications made a part of the job order, and.... (2) When Navy specifications are specified in the contract, the Contractor shall follow Navy... shall make them available to the Government during performance of the contract and for 90 days after...

  18. 48 CFR 3052.217-92 - Inspection and manner of doing work (USCG).

    Science.gov (United States)

    2010-10-01

    ... accordance with the contract, any drawings and specifications made a part of the job order, and any change or... all workmanship, material, equipment, and articles used in the performance of work under this contract... shall make them available to the Government during performance of the contract and for 90 days after...

  19. Children of Working Mothers, March 1977. Special Labor Force Report 217.

    Science.gov (United States)

    Grossman, Allyson Sherman

    1979-01-01

    This special labor force report, focusing on children of working mothers, summarizes findings from the 1977 annual survey of marital and family characteristics of workers in the population who are 16 years old and over. Data are given on: the numbers of children of various ages with working mothers, the percentages of black and white children…

  20. Subtask 2.17 - CO{sub 2} Storage Efficiency in Deep Saline Formations

    Energy Technology Data Exchange (ETDEWEB)

    Gorecki, Charles; Liu, Guoxiang; Braunberger, Jason; Klenner, Robert; Ayash, Scott; Dotzenrod, Neil; Steadman, Edward; Harju, John

    2014-02-01

    As the field of carbon capture and storage (CCS) continues to advance, and large-scale implementation of geologic carbon dioxide (CO{sub 2}) storage progresses, it will be important to understand the potential of geologic formations to store meaningful amounts of CO{sub 2}. Geologic CO{sub 2} storage in deep saline formations (DSFs) has been suggested as one of the best potential methods for reducing anthropogenic CO{sub 2} emission to the atmosphere, and as such, updated storage resource estimation methods will continue to be an important component for the widespread deployment of CCS around the world. While there have been several methodologies suggested in the literature, most of these methods are based on a volumetric calculation of the pore volume of the DSF multiplied by a storage efficiency term and do not consider the effect of site-specific dynamic factors such as injection rate, injection pattern, timing of injection, pressure interference between injection locations, and overall formation pressure buildup. These volumetric methods may be excellent for comparing the potential between particular formations or basins, but they have not been validated through real-world experience or full-formation injection simulations. Several studies have also suggested that the dynamic components of geologic storage may play the most important role in storing CO{sub 2} in DSFs but until now have not directly compared CO{sub 2} storage resource estimates made with volumetric methodologies to estimates made using dynamic CO{sub 2} storage methodologies. In this study, two DSFs, in geographically separate areas with geologically diverse properties, were evaluated with both volumetric and dynamic CO{sub 2} storage resource estimation methodologies to compare the results and determine the applicability of both approaches. In the end, it was determined that the dynamic CO{sub 2} storage resource potential is timedependent and it asymptotically approaches the volumetric CO{sub 2} storage resource potential over very long periods of time in the two systems that were evaluated. These results indicate that the volumetric assessments can be used as long as the appropriate storage efficiency terms are used and it is understood that it will take many wells over very long periods of time to fully realize the storage potential of a target formation. This subtask was funded through the Energy & Environmental Research Center (EERC)– U.S. Department of Energy (DOE) Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FC26-08NT43291. Nonfederal funding was provided by the IEA Greenhouse Gas R&D Programme.

  1. Basic webliography on health promotion and disease prevention - doi:10.5020/18061230.2009.p217

    Directory of Open Access Journals (Sweden)

    Ana Claudia Camargo Gonçalves da Silva

    2012-01-01

    Full Text Available Objectives: To introduce a basic webliography to access highly qualified evidence-based material on health promotion and disease prevention, aiming at the continuing education of health professionals. Methods: By means of Google® browser, applying the descriptors in sequence to progressively refine the search on Internet and key concepts to be learned, all previously defined by the authors themselves, we proceeded a qualitative analyses of the 20 first listed links for each searched issue and the final selection of the most scientifically relevant ones. Results: The 34 selected links are presented in 4 groups: 23 portals, 5 guides and recommendations, 4 scientific journals and 3 blogs that allow free access to health promotion and disease prevention related subjects, such as: concepts; national and international public policies; epidemiology, statistics and health indicators; diseases screening and prophylaxis; counseling for behavior change of health related habits; and interdisciplinary work. Among the selected links 10 (29% are written in English while the others are in Portuguese. Conclusions: The identification of reading materials on health promotion and disease prevention available on Internet, many in Portuguese, allowed us to select relevant scientifically qualified literature and turn it accessible to health professionals, enabling the acquisition of new knowledge or quick update.

  2. Study on laser atomic spectroscopy

    International Nuclear Information System (INIS)

    Laser atomic spectroscopic study on actinium element has been performed in many areas of spectroscopy. The study on characteristic of atomic vapor has been proceeded for copper atom and the spatial density distribution of copper vapor is measured. This experimental data has been compared with the theoretically calculated data. In spectroscopic experiment, the first and second excited states for actinium element are identified and the most efficient ionization scheme for actinium element is identified. In addition, the corrosion problem for filament material due to the heating of the actinium element has been studied. (Author)

  3. In vivo emergence of Aspergillus terreus with reduced azole susceptibility and a Cyp51a M217I alteration

    DEFF Research Database (Denmark)

    Arendrup, Maiken C; Jensen, Rasmus; Grif, Katharina;

    2012-01-01

    Azole resistance in Aspergillus terreus isolates was explored. Twenty related (MB) and 6 unrelated A. terreus isolates were included. CYP51A sequencing and RAPD genotyping was performed. Five MB isolates were itraconazole susceptible, whereas the minimum inhibitory concentrations (MICs) for 15 MB...

  4. A response matrix method for improved modeling of neutron streaming in large control rod holes of prismatic VHTR cores - 217

    International Nuclear Information System (INIS)

    This paper presents a response matrix method developed for accurate modeling of neutron streaming through empty, large control rod holes in VHTRs. In this approach, a response matrix based on transport solution is derived for each control rod channel region and embedded in the whole-core transport solution scheme. Depending on the region geometry only, each element of the response matrix represents the outgoing partial current at a surface due to a unit incoming partial current at another surface. In order to improve the axial solution accuracy, this response matrix approach was incorporated into the DeCART code that solves whole-core transport problems by coupling two-dimensional MOC and one-dimensional nodal solutions. Verification test results showed very good agreements in control rod worth and axial power distributions with MCNP5 solutions. (authors)

  5. Developing Instructional Materials for Productive Skills. Report of a Study Group Meeting (Jakarta, Indonesia, October 2-17, 1979).

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and Oceania.

    In October 1979, representatives of six of the twenty member nations of the Asia Programme of Educational Innovation for Development met in Indonesia to discuss formulation of guidelines for developing instructional materials for teaching productive skills. This report on that conference begins with comments on experiences in materials development…

  6. Tritiated water detection in the 2.17 µM spectral region by cavity ring down spectroscopy

    International Nuclear Information System (INIS)

    Nuclear waste containers are intended to be stored in dedicated disposal sites. For the inside and environmental safety of the disposal sites, the tiny outgassing rates leaking out the containers are measured. Presently, the radioactive HT gas is measured by liquid scintillation. However an alternative method—cavity ring down spectroscopy, an isotopically selective laser technique based on molecular spectroscopy—is currently developed and evaluated for tritium measurement in its oxidized form, HTO. Applying this method, the number density of the gaseous HTO sample hold in the optical cavity cell, is derived from the laser beam absorption by vibrational symmetric stretching 2ν1 (R) HTO lines in the 4590 and 4600 cm−1 spectral range. To ensure a future accurate HTO measurement, the theoretical line intensities are confronted to the experiment: two tritiated water standards are measured with a dedicated CRDS set-up. Compared to the theoretical database, the line positions are correct (−0.067 to −0.128 cm−1), their relative intensities are in agreement with the database, but their absolute intensities are 20% weaker. Among the seven intense lines, the 4596.485 cm−1 line (intensity 8.22 10−22 cm/molecule) and the 4592.407 cm−1 line (intensity 9.83 10−22 cm/molecule) are isolated and intense for a sensitive detection. The HTO detection limit with the present set-up is 3 kBq (10 min), equivalent to 1.8 1012 molecules in the 111 cm3 CRDS cell. This detection limit could be improved by a factor 3 by reducing the detection noise

  7. 41 CFR 101-6.217 - Laws authorizing Federal financial assistance for programs to which this subpart applies.

    Science.gov (United States)

    2010-07-01

    ... distilled spirits, wine, and malt beverages to eleemosynary institutions (26 U.S.C. 5688). (m) Donation of..., preserving and compiling, and publishing of documentary sources significant to the history of the...

  8. 50 CFR 226.217 - Critical habitat for the Gulf of Maine Distinct Population Segment of Atlantic Salmon (Salmo salar).

    Science.gov (United States)

    2010-10-01

    ... reference was approved by the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies of the USGS publication and the maps may be obtained from the USGS, Map Sales, Box..., Knox, Monroe, Montville, Prospect, Searsport, Stockton Springs, Swanville, Thorndike, Waldo,...

  9. Ser217Cys mutation in the Ig Ⅱ domain of FGFR3 in a Chinese family with autosomal dominant achondroplasia

    Institute of Scientific and Technical Information of China (English)

    ZHANG Shi-rong; ZHOU Xiao-qing; REN Xiang; WANG Tian-tian; YUAN Ming-xiong; WANG Qing; LIU Jing-yu; LIU Mu-gen

    2007-01-01

    @@ Achondroplasia (ACH) is the most common form of skeletal dysplasia characterized by disproportionately short stature, lumbar lordosis, relative macrocephaly and other skeletal anomalies resulting from a defect in the maturation of the chondrocytes in the growth plate of the cartilage. The combined frequency of the disease has been estimated to be 1 in 15 000 live births.1 ACH is inherited in autosomal dominant fashion with a complete penetrance, more than 80% of affected individuals have de novo mutations associated with increased paternal age.

  10. PS2-17: Diabetes Social Support Feasibility Pilot Study: Utilizing Mobile Technology and Self-Identified Supporters to Enhance Self-Monitoring of Blood Glucose

    OpenAIRE

    Robinson, Brandi; Roblin, Douglas; Hipkens, James; Vupputuri, Suma; McMahon, Kevin

    2010-01-01

    Background and Aims: Self-monitoring of blood glucose (SMBG) is associated with improved glycemic control among patients with type 2 diabetes, however, the practice of daily self-monitoring is not optimal. Telecommunications technology may improve adherence to recommended self-management practices by remotely transmitting automated reminders to motivate patients, and utilizing social networking for peer support. The purpose of this pilot study is to demonstrate the feasibility and usability o...

  11. 217 km long distance photon-counting optical time-domain reflectometry based on ultra-low noise up-conversion single photon detector

    CERN Document Server

    Shentu, Guo-Liang; Jiang, Xiao; Wang, Xiao-Dong; Pelc, Jason S; Fejer, M M; Zhang, Qiang; Pan, Jian-Wei

    2013-01-01

    We demonstrate a photon-counting optical time-domain reflectometry with 42.19 dB dynamic range using an ultra-low noise up-conversion single photon detector. By employing the long wave pump technique and a volume Bragg grating, we reduce the noise of our up-conversion single photon detector, and achieve a noise equivalent power of -139.7 dBm/sqrt(Hz). We perform the OTDR experiments using a fiber of length 216.95 km, and show that our system can identify defects along the entire fiber length with a distance resolution better than 10 cm in a measurement time of 13 minutes.

  12. Hyperspectral surface materials map of quadrangle 3770, Faizabad (217) and Parkhaw (218) quadrangles, Afghanistan, showing iron-bearing minerals and other materials

    Science.gov (United States)

    King, Trude V.V.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, Keith E.; Giles, Stuart A.; Johnson, Michaela R.

    2013-01-01

    This map shows the spatial distribution of selected iron-bearing minerals and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. This map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Goethite and jarosite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  13. Hyperspectral surface materials map of quadrangle 3770, Faizabad (217) and Parkhaw (218) quadrangles, Afghanistan, showing carbonates, phyllosilicates, sulfates, altered minerals, and other materials

    Science.gov (United States)

    Kokaly, Raymond F.; King, Trude V.V.; Hoefen, Todd M.; Livo, Keith E.; Giles, Stuart A.; Johnson, Michaela R.

    2013-01-01

    This map shows the spatial distribution of selected carbonates, phyllosilicates, sulfates, altered minerals, and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. The map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Epidote or chlorite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  14. The Impact of Education On Fertility and Child Mortality: Do Fathers Really Matter Less than Mothers? OECD Development Centre Working Paper, No. 217 (Formerly Webdoc No. 5)

    Science.gov (United States)

    Breierova, Lucia; Duflo, Esther

    2003-01-01

    This paper takes advantage of a massive school construction program that took place in Indonesia between 1973 and 1978 to estimate the effect of education on fertility and child mortality. Time and region varying exposure to the school construction program generates instrumental variables for the average education in the household, and the…

  15. The crystal structure of franckeite, Pb21.7Sn9.3Fe4.0Sb8.1S56.9

    DEFF Research Database (Denmark)

    Makovicky, Emil; Petricek, Vaclav; Dusek, Michal;

    2011-01-01

    The layer-like crystal structure of franckeite from the mine of San José, Bolivia, exhibits a pronounced one-dimensional transversal wave-like modulation and a non-commensurate layer match in two dimensions. It consists of alternating pseudohexagonal (H) layers and pseudotetragonal (Q) slabs...... was refined as Pb0.74(Sn,Sb)0.26, whereas that of cations, which are adjacent to the interspace with lone electron pairs, with a configuration analogous to that observed in orthorhombic SnS, corresponds to (Sn,Sb)0.73Pb0.27. Iron is dispersed over the octahedral Sn4+ sites in the H layer. Transversal...... and H stacking directions, and the divergence between modulation wave-front and these stacking directions are typical for the composite structures of franckeite and cylindrite. Because of the increased rigidity of the Q component, franckeite usually forms masses of curved crystals rather than...

  16. 26 CFR 1.217-1 - Deduction for moving expenses paid or incurred in taxable years beginning before January 1, 1970.

    Science.gov (United States)

    2010-04-01

    ... or after a substantial period of unemployment or part-time employment, (ii) the beginning of work by... Angeles to visit friends and relatives. In addition, A detours into Mexico for sight-seeing. Because of the stopovers and tour into Mexico, A's travel time and distance are increased over what they...

  17. Melhaoui Mohammed, Peste, contagion et martyre. Histoire du fléau en Occident médiéval, Paris, Publisud, 2005, 217 p.

    Directory of Open Access Journals (Sweden)

    Stéphane Barry

    2007-07-01

    Full Text Available En France, à l’exception des études du médecin, historien et démographe Jean-Noël Biraben (1975-1976, peu de travaux existent sur la Peste noire et ses conséquences dans l’Occident musulman médiéval. On comprendra alors tout l’intérêt de l’ouvrage de Mohammed Melhaoui sur ce thème qu’il connaît bien puisqu’il lui a consacré non seulement une thèse de doctorat d’histoire, mais aussi quelques études portant notamment sur la « perception de la peste en pays chrétiens byzantins et musulman » (Co...

  18. Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis.

    Science.gov (United States)

    Verbout, Norah G; Yu, Xiaolin; Healy, Laura D; Phillips, Kevin G; Tucker, Erik I; Gruber, András; McCarty, Owen J T; Offner, Halina

    2015-02-01

    Multiple sclerosis (MS) is a neuroinflammatory disease characterized by demyelination and axonal damage of the central nervous system. The pathogenesis of MS has also been linked to vascular inflammation and local activation of the coagulation system, resulting in perivascular fibrin deposition. Treatment of experimental autoimmune encephalomyelitis (EAE), a model of human MS, with antithrombotic and antiinflammatory activated protein C (APC) reduces disease severity. Since recombinant APC (Drotecogin alfa), originally approved for the treatment of severe sepsis, is not available for human MS studies, we tested the hypothesis that pharmacologic activation of endogenous protein C could likewise improve the outcome of EAE. Mice were immunized with murine myelin oligodendrocyte glycoprotein (MOG) peptides and at the onset of EAE symptoms, were treated every other day with either WE thrombin (25 μg/kg; i.v.), a selective recombinant protein C activator thrombin analog, or saline control. Mice were monitored for changes in disease score until euthanized for ex vivo analysis of inflammation. Administration of WE thrombin significantly ameliorated clinical severity of EAE, reduced inflammatory cell infiltration and demyelination, suppressed the activation of macrophages comprising the CD11b + population and reduced accumulation of fibrin (ogen) in the spinal cord. These data suggest that symptomatic MS may respond to a treatment strategy that involves temporal pharmacological enhancement of endogenous APC generation. PMID:24810631

  19. 26 CFR 1.217-2 - Deduction for moving expenses paid or incurred in taxable years beginning after December 31, 1969.

    Science.gov (United States)

    2010-04-01

    ... taxpayer's former residence and prior to delivery at the taxpayer's new residence. Expenses paid or... residence and while waiting to enter the new residence or waiting for household goods to arrive, expenses in... between such points. The shortest of the more commonly traveled routes refers to the line of travel...

  20. SU-E-J-217: Multiparametric MR Imaging of Cranial Tumors On a Dedicated 1.0T MR Simulator Prior to Stereotactic Radiosurgery

    International Nuclear Information System (INIS)

    Purpose: Quantitative magnetic resonance imaging (MRI) of cranial lesions prior to stereotactic radiosurgery (SRS) may improve treatment planning and provide potential prognostic value. The practicality and logistics of acquiring advanced multiparametric MRI sequences to measure vascular and cellular properties of cerebral tumors are explored on a 1.0 Tesla MR Simulator. Methods: MR simulation was performed immediately following routine CT simulation on a 1T MR Simulator. MR sequences used were in the order they were performed: T2-Weighted Turbo Spin Echo (T2W-TSE), T2 FLAIR, Diffusion-weighted (DWI, b = 0, 800 to generate an apparent diffusion coefficient (ADC) map), 3D T1-Weighted Fast Field Echo (T1W-FFE), Dynamic Contrast Enhanced (DCE) and Post Gadolinium Contrast Enhanced 3D T1W-FFE images. T1 pre-contrast values was generated by acquiring six different flip angles. The arterial input function was derived from arterial pixels in the perfusion images selected manually. The extended Tofts model was used to generate the permeability maps. Routine MRI scans took about 30 minutes to complete; the additional scans added 12 minutes. Results: To date, seven patients with cerebral tumors have been imaged and tumor physiology characterized. For example, on a glioblastoma patient, the volume contoured on T1 Gd images, ADC map and the pharmacokinetic map (Ktrans) were 1.9, 1.4, and 1.5 cc respectively with strong spatial correlation. The mean ADC value of the entire volume was 1141 μm2/s while the value in the white matter was 811 μm2/s. The mean value of Ktrans was 0.02 min-1 in the tumor volume and 0.00 in the normal white matter. Conclusion: Our initial results suggest that multiparametric MRI sequences may provide a more quantitative evaluation of vascular and tumor properties. Implementing functional imaging during MR-SIM may be particularly beneficial in assessing tumor extent, differentiating radiation necrosis from tumor recurrence, and establishing reliable bio-markers for treatment response evaluation. The Department of Radiation Oncology at Henry Ford Health System has research agreement with Varian Medical System and Philips Health Care

  1. SU-E-J-217: Multiparametric MR Imaging of Cranial Tumors On a Dedicated 1.0T MR Simulator Prior to Stereotactic Radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Wen, N; Glide-Hurst, C; Liu, M; Hearshen, D; Brown, S; Siddiqui, S; Chetty, I [Henry Ford Health System, Detroit, MI (United States)

    2015-06-15

    Purpose: Quantitative magnetic resonance imaging (MRI) of cranial lesions prior to stereotactic radiosurgery (SRS) may improve treatment planning and provide potential prognostic value. The practicality and logistics of acquiring advanced multiparametric MRI sequences to measure vascular and cellular properties of cerebral tumors are explored on a 1.0 Tesla MR Simulator. Methods: MR simulation was performed immediately following routine CT simulation on a 1T MR Simulator. MR sequences used were in the order they were performed: T2-Weighted Turbo Spin Echo (T2W-TSE), T2 FLAIR, Diffusion-weighted (DWI, b = 0, 800 to generate an apparent diffusion coefficient (ADC) map), 3D T1-Weighted Fast Field Echo (T1W-FFE), Dynamic Contrast Enhanced (DCE) and Post Gadolinium Contrast Enhanced 3D T1W-FFE images. T1 pre-contrast values was generated by acquiring six different flip angles. The arterial input function was derived from arterial pixels in the perfusion images selected manually. The extended Tofts model was used to generate the permeability maps. Routine MRI scans took about 30 minutes to complete; the additional scans added 12 minutes. Results: To date, seven patients with cerebral tumors have been imaged and tumor physiology characterized. For example, on a glioblastoma patient, the volume contoured on T1 Gd images, ADC map and the pharmacokinetic map (Ktrans) were 1.9, 1.4, and 1.5 cc respectively with strong spatial correlation. The mean ADC value of the entire volume was 1141 μm2/s while the value in the white matter was 811 μm2/s. The mean value of Ktrans was 0.02 min-1 in the tumor volume and 0.00 in the normal white matter. Conclusion: Our initial results suggest that multiparametric MRI sequences may provide a more quantitative evaluation of vascular and tumor properties. Implementing functional imaging during MR-SIM may be particularly beneficial in assessing tumor extent, differentiating radiation necrosis from tumor recurrence, and establishing reliable bio-markers for treatment response evaluation. The Department of Radiation Oncology at Henry Ford Health System has research agreement with Varian Medical System and Philips Health Care.

  2. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: pooled analysis of 82 population-based studies with 217,000 participants

    OpenAIRE

    Danaei, Goodarz; Fahimi, Saman; Lu, Yuan; Zhou, Bin; Hajifathalian, Kaveh; Di Cesare, Mariachiara; Ezzati, Majid; NCD-RisC, Group

    2015-01-01

    Background: Diabetes has been defi ned on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA1c. We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classifi cation of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in ...

  3. EFSA CEF Panel (EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids), 2013. Scientific Opinion on Flavouring Group Evaluation 217, Revision 1 (FGE.217Rev1). Consideration of genotoxic potential for α,β-Unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: Lactones

    DEFF Research Database (Denmark)

    Beltoft, Vibe Meister; Binderup, Mona-Lise; Lund, Pia;

    the Procedure. Additional data on genotoxicity for the three representative substances, 5-ethyl-3-hydroxy-4-methylfuran-2(5H)-one [FL-no: 10.023], 3,4-dimethyl-5-pentylidenefuran-2(5H)-one [FL-no: 10.042] and furan-2(5H)-one [FL-no: 10.066], have now been provided. Based on the new data, the Panel concluded...... that 5-ethyl-3-hydroxy-4-methylfuran-2(5H)-one [FL-no: 10.023] does not give rise to concern with respect to genotoxicity and can accordingly, together with the structurally related substance, 3-hydroxy-4,5-dimethylfuran-2(5H)-one [FL-no: 10.030] for which it is a representative, be evaluated using...... the Procedure. For 3,4-dimethyl-5-pentylidenefuran-2(5H)-one [FL-no: 10.042] and furan-2(5H)-one [FL-no: 10.066] the concern for genotoxicity could not be ruled out and a combined micronucleus and Comet assay is requested for these two substances, covering the remaining seven substances [FL-no: 10.034, 10...

  4. 10 CFR Appendix E to Part 20 - Nationally Tracked Source Thresholds

    Science.gov (United States)

    2010-01-01

    ... Category 1(TBq) Category 1(Ci) Category 2(TBq) Category 2(Ci) Actinium-227 20 540 0.2 5.4 Americium-241 60... 2 54 Strontium-90 1,000 27,000 10 270 Thorium-228 20 540 0.2 5.4 Thorium-229 20 540 0.2 5.4...

  5. I. The metabolic properties of plutonium and allied materials

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, J.G.

    1948-05-24

    This report on the metabolic properties of plutonium and related radioactive materials presents experimental information in the following areas: radioautographic studies; tracer studies (with tables of accumulation in tissues) of actinium, radio-zirconium, technetium, radio-rubidium, radio-germanium, beryllium, and cadmium; decontamination and bone metabolism studies; and radio-chemical isolation.

  6. 10 CFR Appendix B to Part 20 - Annual Limits on Intake (ALIs) and Derived Air Concentrations (DACs) of Radionuclides for...

    Science.gov (United States)

    2010-01-01

    .... Actinium Ac 89 Aluminum Al 13 Americium Am 95 Antimony Sb 51 Argon Ar 18 Arsenic As 33 Astatine At 85... Curium Cm 96 Dysprosium Dy 66 Einsteinium Es 99 Erbium Er 68 Europium Eu 63 Fermium Fm 100 Fluorine F...

  7. Effect of 17-DMAG on proliferation and apoptosis of human hepatic satellite cell line LX2%17-DMAG对人LX2肝星状细胞增殖及凋亡作用的研究

    Institute of Scientific and Technical Information of China (English)

    庄敏; 王春波

    2014-01-01

    Objective To investigate the effect of Heat Shock Protein 90 (HSP90) inhibitor 17-DMAG on the proliferation and apoptosis of human hepatic satellite cell line LX2 cells in vitro. Methods The LX2 cells were cultured in vitro. The inhibitory effect of 17-DMAG on LX2 cells in different time and concentration was assayed by MTT assay. Flow cytometry was used to test the apoptosis of 17-DMAG interfered cells. The expression of α-SMA protein was detected by Western blot and compared with control group. Results The results showed that 17-DMAG could inhibit the growth of LX2 cells in a time and concentration dependent manner (P<0.01). With the increase of concentration of 17-DMAG, and the time interfered, the amount of live cells decreased. The apoptosis effect of 17-DMAG on LX2 cells was confirmed by flow cytometry, compared with control group, the apoptosis rate of the interfered group increased obviously(P<0.01). Western blot showed that 17-DMAG could decreased the expression of α-SMA. Conclusion 17-DMAG could inhibit the proliferation of LX2 cells in a concentrate and time dependent manners by inducing their apoptosis, and later decrease the expression ofα-SMA to inhibit the production of collagen.%目的:研究HSP90抑制剂17-DMAG在体外对人LX2肝星状细胞生长增殖及细胞凋亡的作用。方法体外培养人LX2肝星状细胞,用细胞毒试验法(MTT)观察不同浓度和作用时间的17-DMAG对LX2细胞的生长抑制作用;流式细胞仪检测药物作用后LX2细胞凋亡的发生;Western blot检测α-SMA的表达,并与对照组进行对比。结果17-DMAG能抑制人LX2肝星状细胞生长,且呈浓度和时间依赖性(P<0.01),随药物浓度加大和作用时间延长,存活细胞数量逐渐减少;流式细胞仪证实17-DMAG可诱导LX2细胞凋亡,与对照组比较,实验组细胞凋亡率明显增加(P<0.01);Western blot可以证实17-DMAG可使LX2细胞α-SMA表达减少,与对照组比较差异有统计学意义(P<0.05)。结论17-DMAG可呈浓度和时间依赖性的抑制人LX2肝星状细胞的生长,其机制为诱导细胞凋亡,并且通过这种机制来减少α-SMA的表达来抑制胶原的产生。

  8. Ulnar ray defect in an infant with a 6q21;7q31.2 translocation: Further evidence of the existence of a limb defect gene in 6q21

    Energy Technology Data Exchange (ETDEWEB)

    Gurrieri, F.; Genuardi, M.; Pomponi, M.G. [Universita di Palermo (Italy)] [and others

    1995-01-30

    Ectrodactyly is a developmental defect of the distal limbs characterized by marked clinical variability and genetic heterogeneity, also reflected in the observation of different chromosome abnormalities nonrandomly associated with longitudinal postaxial limb deficiencies. The one most frequently found in patients with split hand-split foot (SHSF) involves chromosome band 7q22. Recently, structural anomalies of chromosome 6q21 have been reported in 2 unrelated patients with SHSF, suggesting that this region may also contain genes responsible for limb development. We report on a third patient who had a de novo, apparently balanced t(6;7)(q21;q31.2) translocation and bilateral ulnar aplasia with postaxial oligodactyly. In spite of the different phenotypic effects observed in these 3 patients, we consider our case as further evidence that genes in 6q21 may play a role in distal limb development. 8 refs., 3 figs.

  9. 熔体快淬法制备2:17型ReCo(Re=Sm,Ho,Er)合金薄带的磁性能研究%Magnetic Property of 2:17 Type Re(CobalFe0.10Cu0.08Zr0.03)7.55 (Re=Sm, Ho, Er)Alloy Ribbons Prepared by a Melt-Spun Method

    Institute of Scientific and Technical Information of China (English)

    龚维幂; 高润生; 于荣海

    2010-01-01

    通过熔体快淬法制各了Re(CobalFe0.10Cu0.08Zr0.03)7.55(Re=Sin,Ho,Er)合金,并对室温、高温磁性能进行了研究.结果表明,Ho元素取代50%Sm元素的(Sm0.5H00.5XCobalFe0.10Cue08zr0.03)7.55合金具有良好的室温磁性能,合金薄带矫顽力超过800kA/m.Sm(CobaiFe0.10Cu0.08Zr0.03)7.55合金薄带矫顽力随温度上升先下降后上升,至400℃达到峰值,随即开始快速减小;其饱和磁化强度随温度升高不断降低.(Sm0.5H00.5)(CobaiFe0.10Cu0.08Zr0.03)7.55试样的矫顽力随温度上升逐渐下降;其饱和磁化强度则随温度上升先逐渐升高至400℃达到峰值,然后开始降低.温度高于250℃时,未进行重稀土元素取代的样品相对矫顽力水平较高;300℃以上,Ho取代50%Sm元素的试样其饱和磁化强度具有明显的优势.对Ho取代比例进行有针对性的优化有望成为获得优良的高温磁性能的有效途径.

  10. Investigation for determining the retention properties of rock over the ASSE II mine for dissolved radionuclides

    International Nuclear Information System (INIS)

    For a model consideration of groundwater movement and the associated transport of dissolved substance in deep groundwater, the retention properties of the ASSE II mine for radionuclides dissolved in water were determined. A series of properties of rocks were examined and described for this purpose. Apart from the chemical, mineralogical and petrophysical characteristics of the rocks, the retention was determined by 3 different methods and stated in the form of distribution coefficients for specific elements. A comparison of the results of vibration and diffusion experiments gave good agreement, while the results in through column experiments only reached the same order of magnitude after an expensive determination with the aid of a place concentration distribution. The distribution coefficients for the elements carbon, selenium, strontium, technetium, iodine, caesium, lead, radium, actinium, proto-actinium, uranium, neptunium, plutonium, americium and curium are listed and collected for model rock packages. (orig./HP)

  11. LASL experience in decontamination of the environment

    International Nuclear Information System (INIS)

    This discussion represents one part of a major effort in soil decontamination at the Los Alamos site. A contaminated industrial waste line in the Los Alamos townsite was removed, and a plutonium incineration facility, and a filter building contaminated with actinium-227 were dismantled. The former plutonium handling facility has been decontaminated, and canyons and an old firing site contaminated with strontium-90 have been surveyed

  12. Sorption studies of radioelements on geological materials

    OpenAIRE

    Berry, J. A; 油井 三和; 北村 暁

    2007-01-01

    Batch sorption experiments have been carried out to study the sorption of uranium, technetium, curium, neptunium, actinium, protactinium, polonium, americium and plutonium onto bentonite, granodiorite and tuff. Mathematical modelling using the HARPHRQ program and the HATCHES database was carried out to predict the speciation of uranium and technetium in the equilibrated seawater, and neptunium, americium and plutonium in the rock equilibrated water. Review of the literature for thermodynamic ...

  13. Study of the origin of elements of the uranium-235 family observed in excess in the vicinity of the experimental nuclear EL4 reactor under dismantling. Lessons got at this day and conclusions; Etude de l'origine des elements de la famille de l'uranium-235 observes en exces dans les environs du reacteur nucleaire experimental EL4 en cours de demantelement. Enseignements retires a ce jour et conclusion

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This study resumes the discovery of an excess of actinium 227 found around by EL4 nuclear reactor actually in dismantling. The search for the origin of this excess revealed a real inquiry of investigation during three years. Because a nuclear reactor existed in this area a particular attention will have concerned this region. The doubt became the line of conduct to find the answer to the human or natural origin of this excess. Finally and against any evidence, it appears that the origin of this phenomenon was natural, consequence of the particular local geology. The detail of the different investigations is given: search of a possible correlation with the composition of elevations constituent of lanes, search (and underlining) of new sites in the surroundings of the Rusquec pond and the Plouenez station, study of the atmospheric deposits under winds of the nuclear power plant and in the east direction, search of a possible relationship with the gaseous effluents of the nuclear power plant in the past, historical study of radioactive effluents releases in the fifty last years by the analysis of the sedimentary deposits in the Saint-Herbiot reservoir, search of a possible correlation between the excess of actinium 227 and the nuclear power plant activity; search of a possible correlation with a human activity without any relationship with the nuclear activities, search of a correlation with the underground waters, search of a correlation with the geological context, collect of information on the possible transfers in direction of the food chain, determination of the radiological composition of the underground waters ( not perturbed by human activity), search of the cause of an excess of actinium 227 in the old channel of liquid effluents release of the nuclear power plant. The results are given and discussed. And contrary to all expectations the origin of the excess of actinium 227 is completely natural. (N.C.)

  14. The discoveries of uranium 237 and symmetric fission — From the archival papers of Nishina and Kimura

    OpenAIRE

    IKEDA, Nagao

    2011-01-01

    Shortly before the Second World War time, Nishina reported on a series of prominent nuclear physical and radiochemical studies in collaboration with Kimura. They artificially produced 231Th, a member of the natural actinium series of nuclides, by bombarding thorium with fast neutrons. This resulted in the discovery of 237U, a new isotope of uranium, by bombarding uranium with fast neutrons, and confirmed that 237U disintegrates into element 93 with a mass number of 237. They also identified t...

  15. System for recovery of daughter isotopes from a source material

    Science.gov (United States)

    Tranter, Troy J [Idaho Falls, ID; Todd, Terry A [Aberdeen, ID; Lewis, Leroy C [Idaho Falls, ID; Henscheid, Joseph P [Idaho Falls, ID

    2009-08-04

    A method of separating isotopes from a mixture containing at least two isotopes in a solution is disclosed. A first isotope is precipitated and is collected from the solution. A daughter isotope is generated and collected from the first isotope. The invention includes a method of producing an actinium-225/bismuth-213 product from a material containing thorium-229 and thorium-232. A solution is formed containing nitric acid and the material containing thorium-229 and thorium-232, and iodate is added to form a thorium iodate precipitate. A supernatant is separated from the thorium iodate precipitate and a second volume of nitric acid is added to the thorium iodate precipitate. The thorium iodate precipitate is stored and a decay product comprising actinium-225 and bismuth-213 is generated in the second volume of nitric acid, which is then separated from the thorium iodate precipitate, filtered, and treated using at least one chromatographic procedure. A system for producing an actinium-225/bismuth-213 product is also disclosed.

  16. Experiment list: SRX065708 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available annel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...genotype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  17. Experiment list: SRX065717 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nnel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...ype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  18. Experiment list: SRX065707 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available annel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...genotype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  19. Experiment list: SRX065710 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nnel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...enotype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  20. Experiment list: SRX065709 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nnel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...enotype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  1. Experiment list: SRX065716 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available annel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...type=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  2. Experiment list: SRX065715 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available annel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...type=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  3. Experiment list: SRX065718 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nnel_1 || strain=OP217(official name : OP217 genotype : unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) outcross : 3 transgene... : aly-2 tags : Bombard tag : GFP::3xFlag description : This strain's transgene...ype=unc119(ed3);wgIs217(aly-2:TY1 EGFP FLAG;unc119) || Sex=Hermaphrodite || transgene

  4. Grupo de Estudios en Historia de las Ciencias, GEHC (Editores). Control Social y Objetivación : escrituras y tránsitos de las Ciencias en Chile, Universidad de Chile, Santiago de Chile, 2012. 217 p.

    OpenAIRE

    Pincheira Torres, Ivan

    2012-01-01

    Las articulaciones existentes entre discurso científico y prácticas de gobierno no han quedado fuera del campo de problematización de los estudios sociales latinoamericanos. De este modo, y aunque se ubiquen en distintas matrices de análisis, nos encontramos con distintos trabajos que van a reconocer la relevante labor desempeñada por las epistemologías europeas en la conformación de prácticas de gobierno que, actuando sobre estructuras tanto subjetivas como sociales, perpetuarán relaciones d...

  5. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    P. Bernot

    2005-07-13

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this activity is to predict dissolved concentrations or solubility limits for elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) relevant to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are provided in the form of tabulated functions with pH and log fCO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. Even though selection of an appropriate set of radionuclides documented in Radionuclide Screening (BSC 2002 [DIRS 160059]) includes actinium, transport of Ac is not modeled in the total system performance assessment for the license application (TSPA-LA) model because of its extremely short half-life. Actinium dose is calculated in the TSPA-LA by assuming secular equilibrium with {sup 231}Pa (Section 6.10); therefore, Ac is not analyzed in this report. The output data from this report are fundamental inputs for TSPA-LA used to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for the actinides discussed in this report. These models cover broad ranges of environmental conditions so they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or

  6. Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)

    Energy Technology Data Exchange (ETDEWEB)

    Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State

    2015-10-01

    We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples

  7. Dicty_cDB: Contig-U14370-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available n 73 Query: 74 ggtattgntgaaactgaattactatcncataatnaatccnatgaaaaagttttnnacnca 133 ||||||||||||||||||||||||||||...|||||||||||||||||||||||||||||||| Sbjct: 74 ggtattgntgaaactgaattactatcncataatnaatccnatgaaaaagttttnnacnca 133 ...||||| Sbjct: 217 tcaaatacaattaaaaaanaagntgntcnaaaaaatgtnagagtaatgatnatttccccn 158 Query: 74 ggtattgntgaaactgaattactatcncataatnaatccna...|||||||||||||||||||||||||||| Sbjct: 157 ggtattgntgaaactgaattactatcncataatnaatccnatgaaaaagttttnnacnca 98 Quer

  8. Low background counting of 222Rn, 220Rn and 219Rn with electrostatic counters

    Science.gov (United States)

    Mong, Brian; EXO-200 Collaboration; nEXO Collaboration

    2014-09-01

    The radon counting technique based on electrostatic precipitation of progenies in gas followed by alpha spectroscopy has been applied to support the material selection programs of low background, neutrino and dark matter experiments with emphasis on EXO. An array of 8 counters operated by Laurentian University at SNOLAB and the Waste Isolation Pilot Plant have reached the sensitivity of 10 atoms/day in the uranium, thorium and actinium chains. Hardware improvements are underway to further increase the capacity and sensitivity in support of nEXO. The radon counting technique based on electrostatic precipitation of progenies in gas followed by alpha spectroscopy has been applied to support the material selection programs of low background, neutrino and dark matter experiments with emphasis on EXO. An array of 8 counters operated by Laurentian University at SNOLAB and the Waste Isolation Pilot Plant have reached the sensitivity of 10 atoms/day in the uranium, thorium and actinium chains. Hardware improvements are underway to further increase the capacity and sensitivity in support of nEXO. Supported by NSERC Project Grants ``Search for Double Beta Decay with EXO.''

  9. Purification of cerium, neodymium and gadolinium for low background experiments

    Science.gov (United States)

    Boiko, R. S.; Barabash, A. S.; Belli, P.; Bernabei, R.; Cappella, F.; Cerulli, R.; Danevich, F. A.; Incicchitti, A.; Laubenstein, M.; Mokina, V. M.; Nisi, S.; Poda, D. V.; Polischuk, O. G.; Tretyak, V. I.

    2014-01-01

    Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search), 136Ce (2β+ candidate with one of the highest Q2β). The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides) was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  10. Mixed valency of the RE and Ac ions in solid states

    International Nuclear Information System (INIS)

    Full text: This review is devoted to consideration of the methods and results of the theoretical and experimental investigations of the electronic state of the rare earths and actinium ions in the separate compound. The methods of the high resolution X ray spectroscopy were used for our consideration. Energy of the X ray lines of the rare earths and actinium ions in free state and solid states was study carefully. Valency shifts of X Ray lines under change of electronic state of nf - ions in different oxide, fluoride and chloride compounds were determined for K -, L- and M - lines for these ions with accuracy near 10 -100 MeV. We studied the electronic state of nf- ions which is changed from '+2' to '+4' and determined the concentration of ions in different electronic state. Relative error for theoretical energy of the most lines for HFP - approach in comparison with experiment is less than 0.5%, and deviation for concentration is less than 5%

  11. The Technological Enhancement of Normally Occurring Radioactive Materials in Red Mud due to the Production of Alumina

    Directory of Open Access Journals (Sweden)

    Maurice O. Miller

    2016-01-01

    Full Text Available This study investigates the level of technological enhancement of normally occurring radioactive materials (TENORM in the red mud waste due to the production of alumina in Jamaica. Technological enhancements factors (TEF were determined for the uranium, thorium, actinium series, their progenies, and the nonseries potassium-40 using gamma spectrometry. The study concluded that bauxite production technologically enhances the uranium progenies Th-234, Pb-214, Bi-214, and Pa-234 and the thorium-232 progenies Ac-228, Pb-212, and Bi-212 in red mud. The actinium series was technologically enhanced, but K-40 and the thorium daughter, Tl-208, were reduced. The spectrometric comparison of Tl-208 (at 510 keV was unexpected since its other photopeaks at 583 keV, 934 keV, and 968 keV were markedly different. An explanation for this anomaly is discussed. An explanation regarding the process of accumulation and fractionation of organically derived phosphate deposits and potassium-feldspar is offered to explain the spectrometric differences between the alumina product and its waste material, red mud.

  12. A study of uranium and thorium migration at the Koongarra uranium deposit with application to actinide transport from nuclear waste repositories

    International Nuclear Information System (INIS)

    One way to gain confidence in modelling possible radionuclide releases is to study natural systems which are similar to components of the multibarrier waste repository. Several such analogues are currently under study and these provide useful data about radionuclide behaviour in the natural environment. One such system is the Koongarra uranium deposit in the Northern Territory. In this dissertation, the migration of actinides, primarily uranium and thorium, has been studied as an analogue for the behaviour of transuranics in the far-field of a waste repository. The major findings of this study are: 1. the main process retarding uranium migration in the dispersion fan at Koongarra is sorption, which suppresses dissolved uranium concentrations well below solubility limits, with ferrihydrite being a major sorbing phase; 2. thorium is extremely immobile, with very low dissolved concentrations and corresponding high distribution ratios for 230Th. Overall, it is estimated that colloids are relatively unimportant in Koongarra groundwater. Uranium migrates mostly as dissolved species, whereas thorium and actinium are mostly adsorbed to larger, relatively immobile particles and the stationary phase. However, of the small amount of 230Th that passes through a 1μm filter, a significant proportion is associated with colloidal particles. Actinium appears to be slightly more mobile than thorium and is associated with colloids to a greater extent, although generally present in low concentrations. These results support the possibility of colloidal transport of trivalent and tetravalent actinides in the vicinity of a nuclear waste repository. 112 refs., 23 tabs., 32 figs

  13. Purification of cerium, neodymium and gadolinium for low background experiments

    Directory of Open Access Journals (Sweden)

    Boiko R.S.

    2014-01-01

    Full Text Available Cerium, neodymium and gadolinium contain double beta active isotopes. The most interesting are 150Nd and 160Gd (promising for 0ν2β search, 136Ce (2β+ candidate with one of the highest Q2β. The main problem of compounds containing lanthanide elements is their high radioactive contamination by uranium, radium, actinium and thorium. The new generation 2β experiments require development of methods for a deep purification of lanthanides from the radioactive elements. A combination of physical and chemical methods was applied to purify cerium, neodymium and gadolinium. Liquid-liquid extraction technique was used to remove traces of Th and U from neodymium, gadolinium and for purification of cerium from Th, U, Ra and K. Co-precipitation and recrystallization methods were utilized for further reduction of the impurities. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe gamma spectrometry. As a result of the purification procedure the radioactive contamination of gadolinium oxide (a similar purification efficiency was reached also with cerium and neodymium oxides was decreased from 0.12 Bq/kg to 0.007 Bq/kg in 228Th, from 0.04 Bq/kg to <0.006 Bq/kg in 226Ra, and from 0.9 Bq/kg to 0.04 Bq/kg in 40K. The purification methods are much less efficient for chemically very similar radioactive elements like actinium, lanthanum and lutetium.

  14. 75 FR 67719 - Proposed Consent Decree, Clean Air Act Citizen Suit

    Science.gov (United States)

    2010-11-03

    .... Jackson, No. 10-cv-02859-PJH (N.D. Cal.). Plaintiff filed a deadline suit to compel the Administrator to... (ICAPCD) Rules 201, 202 and 217 submitted to the Environmental Protection Agency (EPA) on or about August... deadlines for EPA's action on ICAPCD Rules 201, 202 and 217. DATES: Written comments on the proposed...

  15. EST Table: BY915709 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available %/217 aa ref|XP_001846858.1| spectrin beta chain [Culex quinquefasciatus] gb|EDS44827.1| spectrin beta chain... gnl|Amel|GB11407-PA 10/09/10 90 %/217 aa gi|91081397|ref|XP_976147.1| PREDICTED: similar to beta chain spectrin isoform 2 [Tribolium castaneum] BY915709 maV3 ...

  16. 76 FR 67229 - Governors' Designees Receiving Advance Notification of Transportation of Certain Shipments of...

    Science.gov (United States)

    2011-10-31

    ... Nuclear Waste and Spent Fuel On January 6, 1982 (47 FR 596 and 47 FR 600), the U.S. Nuclear Regulatory...: (217) 782-7860, Fax: (217) 558- 7398 INDIANA Major Jeffrey L. Walker, Commander, SAME. Commercial...-2200, Fax: (518) 322- 4978 NORTH CAROLINA First Sergeant Shane S. Manuel, North SAME. Carolina...

  17. EST Table: FS909084 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS909084 E_FL_fufe_16C18_F_0 10/09/28 56 %/217 aa ref|XP_001653706.1| glutathione s...ynthetase [Aedes aegypti] gb|EAT39012.1| glutathione synthetase [Aedes aegypti] 10/09/12 54 %/217 aa FBpp024

  18. Benthic harpacticoid copepod community of Saphala salt marsh along the west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Ingole, B.S.; Ansari, Z.A; Parulekar, A

    stream_size 4 stream_content_type text/plain stream_name Indian_J_Mar_Sci_19_217.pdf.txt stream_source_info Indian_J_Mar_Sci_19_217.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  19. NCBI nr-aa BLAST: CBRC-AGAM-07-0045 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-AGAM-07-0045 ref|ZP_01061096.1| copper/silver efflux P-type ATPase [Flavobacte...rium sp. MED217] gb|EAQ49147.1| copper/silver efflux P-type ATPase [Leeuwenhoekiella blandensis MED217] ZP_01061096.1 1e-128 60% ...

  20. 26 CFR 1.1232-3A - Inclusion as interest of original issue discount on certain obligations issued after May 27, 1969.

    Science.gov (United States)

    2010-04-01

    ... of the Federal Reserve. See 12 CFR 217.4(d). The stated redemption price at maturity is $13,382.26..., Regulation Q of the Board of Governors of the Federal Reserve System. See 12 CFR 217.4(d). Interest will be... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Inclusion as interest of original issue...

  1. 76 FR 14587 - Defense Federal Acquisition Regulation Supplement; Multiyear Contract Authority for Electricity...

    Science.gov (United States)

    2011-03-17

    ... rule at 75 FR 34942 on June 21, 2010, to amend DFARS parts 217 and 241 to authorize the Department of... the approach described in the interim rule published at 75 FR 34942 on June 21, 2010, to be the most... Accordingly, the interim rule amending 48 CFR parts 217 and 241, which was published at 75 FR 34942 on June...

  2. Biochemical composition of zooplankton from the northern Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Bhat, K.L.; Sreepada, R.A.; Ansari, Z.A.

    stream_size 7 stream_content_type text/plain stream_name Pak_J_Mar_Sci_2_17.pdf.txt stream_source_info Pak_J_Mar_Sci_2_17.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  3. Gclust Server: 121213 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 121213 HSA_113426727 Cluster Sequences Related Sequences(20) 217 XP_001131030.1 PRE...DICTED: hypothetical protein ; no annotation 1 1.00e-99 0.0 0.0 0.0 0.0 0.0 12.5 Show 121213 Cluster ID 12121...equences(20) Sequence length 217 Representative annotation XP_001131030.1 PREDICT

  4. 78 FR 43850 - Opportunity for Designation in Owensboro, KY; Bloomington, IL; Iowa Falls, IA; Casa Grande, AZ...

    Science.gov (United States)

    2013-07-22

    ... State Route 217; State Route 217 east to Prairie Dog Town Fork of the Red River; Prairie Dog Town Fork of the Red River southeast to the Briscoe County line; the northern Briscoe County line; the northern..., Lake of the Woods, Marshall, Beltrami, Polk, Pennington, Red Lake, and Clearwater Counties. In...

  5. 75 FR 36348 - Opportunity for Designation in the Amarillo, TX; Cairo, IL; and State of North Carolina Areas

    Science.gov (United States)

    2010-06-25

    ... Donley County; the southern Donley and Armstrong County lines west to Prairie Dog Town Fork of the Red River; Prairie Dog Town Fork of the Red River northwest to State Route 217; State Route 217 west to FM... Carolina) official agencies will end on September 30, 2010. In the March 31, 2010, Federal Register (71...

  6. Mrp2 is essential for estradiol-17 beta(beta-D-glucuronide)-induced cholestasis in rats

    NARCIS (Netherlands)

    Huang, LY; Smit, JW; Meijer, DKF; Vore, M

    2000-01-01

    The present study evaluates the roles of the multidrug resistance-1 P-glycoprotein, Mdr1a/1b, the bile salt export pump (Bsep), and the multidrug resistance-associated protein-2 (Mrp2) in mediating cholestasis induced by estradiol-17 beta(beta-D-glucuronide) (E(2)17G). Administration of [H-3]E(2)17G

  7. EST Table: BP117858 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available iquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Protein effete)...ilar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum] FS793905 ce-- ...

  8. 76 FR 72422 - Draft Guidance for Industry on Evaluating the Effectiveness of Anticoccidial Drugs in Food...

    Science.gov (United States)

    2011-11-23

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Evaluating the Effectiveness... draft guidance for industry 217 entitled ``Evaluating the Effectiveness of Anticoccidial Drugs in Food... and food-producing mammals. Draft guidance for industry 217 supersedes the CVM draft guidance...

  9. Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013.

    Science.gov (United States)

    du Plessis, Mignon; Allam, Mushal; Tempia, Stefano; Wolter, Nicole; de Gouveia, Linda; von Mollendorf, Claire; Jolley, Keith A; Mbelle, Nontombi; Wadula, Jeannette; Cornick, Jennifer E; Everett, Dean B; McGee, Lesley; Breiman, Robert F; Gladstone, Rebecca A; Bentley, Stephen D; Klugman, Keith P; von Gottberg, Anne

    2016-05-01

    Serotype 1 is an important cause of invasive pneumococcal disease in South Africa and has declined following the introduction of the 13-valent pneumococcal conjugate vaccine in 2011. We genetically characterized 912 invasive serotype 1 isolates from 1989 to 2013. Simpson's diversity index (D) and recombination ratios were calculated. Factors associated with sequence types (STs) were assessed. Clonal complex 217 represented 96% (872/912) of the sampled isolates. Following the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13), ST diversity increased in children 14 years (D, 0.35 to 0.54, P 14 years (242/305 [79%] versus 96/148 [65%], P = 0.001), whereas ST-9067 increased (4/684 [0.6%] versus 24/228 [11%], P < 0.001). Three subclades were identified within ST-217: ST-217C1 (353/382 [92%]), ST-217C2 (15/382 [4%]), and ST-217C3 (14/382 [4%]). ST-217C2, ST-217C3, and single-locus variant (SLV) ST-8314 (20/912 [2%]) were associated with nonsusceptibility to chloramphenicol, tetracycline, and co-trimoxazole. ST-8314 (20/912 [2%]) was also associated with increased nonsusceptibility to penicillin (P < 0.001). ST-217C3 and newly reported ST-9067 had higher recombination ratios than those of ST-217C1 (4.344 versus 0.091, P < 0.001; and 0.086 versus 0.013, P < 0.001, respectively). Increases in genetic diversity were noted post-PCV13, and lineages associated with antimicrobial nonsusceptibility were identified. PMID:26962082

  10. Radionuclide interactions with marine sediments

    International Nuclear Information System (INIS)

    A critical review of the literature on the subject of the interactions of radionuclides with marine sediments has been carried out. On the basis of the information available, an attempt has been made to give ranges and 'best estimates' for the distribution ratios between seawater and sediments. These estimates have been based on an understanding of the sediment seawater system and the porewater chemistry and mineralogy. Field measurements, laboratory measurements and estimates based on stable-element geochemical data are all taken into account. Laboratory measurements include distribution-ratio and diffusion-coefficient determinations. The elements reviewed are carbon, chlorine, calcium, nickel, selenium, strontium, zirconium, niobium, technetium, tin, iodine, caesium, lead, radium, actinium, thorium, protactinium, uranium, neptunium, plutonium, americium and curium. (author)

  11. Process for radioisotope recovery and system for implementing same

    Science.gov (United States)

    Meikrantz, David H.; Todd, Terry A.; Tranter, Troy J.; Horwitz, E. Philip

    2007-01-02

    A method of recovering daughter isotopes from a radioisotope mixture. The method comprises providing a radioisotope mixture solution comprising at least one parent isotope. The at least one parent isotope is extracted into an organic phase, which comprises an extractant and a solvent. The organic phase is substantially continuously contacted with an aqueous phase to extract at least one daughter isotope into the aqueous phase. The aqueous phase is separated from the organic phase, such as by using an annular centrifugal contactor. The at least one daughter isotope is purified from the aqueous phase, such as by ion exchange chromatography or extraction chromatography. The at least one daughter isotope may include actinium-225, radium-225, bismuth-213, or mixtures thereof. A liquid-liquid extraction system for recovering at least one daughter isotope from a source material is also disclosed.

  12. Proposed training program for construction personnel involved in remedial action work at sites contaminated by naturally occurring radionuclides

    International Nuclear Information System (INIS)

    Many sites used during the early days of the US atomic energy program are contaminated with radionuclides of the primordial decay chains (uranium, thorium, and actinium series). This contamination consists of residues resulting from refining and processing uranium and thorium. Preparation of these sites for release to unrestricted private use will involve the assistance of construction workers, many of whom have limited knowledge of the hazards associated with radioactive materials. Therefore, there is a need to educate these workers in the fundamentals of radioactive material handling to minimize exposures and possible spread of contamination. This training should disseminate relevant information at an appropriate educational level and should instill a cautious, common-sense attitude toward the handling of radioactive materials. The training should emphasize basic information concerning environmental radiation within a context of relative risk. A multi-media format, including colorful visual aids, demonstration, and discussion, should be used to maximize motivation and retention. A detailed, proposed training program design is presented

  13. JAEA thermodynamic database for performance assessment of geological disposal of high-level and TRU wastes. Refinement of thermodynamic data for trivalent actinoids and samarium

    International Nuclear Information System (INIS)

    Within the scope of the JAEA thermodynamic database project for performance assessment of geological disposal of high-level radioactive and TRU wastes, the refinement of the thermodynamic data for the inorganic compounds and complexes of trivalent actinoids (actinium(III), plutonium(III), americium(III) and curium(III)) and samarium(III) was carried out. Refinement of thermodynamic data for these elements was based on the thermodynamic database for americium published by the Nuclear Energy Agency in the Organisation for Economic Co-operation and Development (OECD/NEA). Based on the similarity of chemical properties among trivalent actinoids and samarium, complementary thermodynamic data for their species expected under the geological disposal conditions were selected to complete the thermodynamic data set for the performance assessment of geological disposal of radioactive wastes. (author)

  14. Theoretical Study on Properties of New Isotope 265Bh

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The properties of nuclei belonging to the newly observed α-decay chain starting from 265Bh have been studied. The axially deformed relativistic mean-field calculation with the force NL-Z2 has been performed in the blockedBCS approximation. Some ground state properties such as binding energies, deformations, spins, and parities, as well as Q-values of the α-decay for this decay chain have been calculated and compared with known experimental data. Good agreement is found. The single-particle spectrum of the nucleus 265 Bh is studied and some new magic numbers are found,while the magnitudes of the shell gaps in superheavy nuclei are much smaller than those of nuclei before the actinium region, and the Fermi surfaces are close to the continuum. Thus the superheavy nuclei are usually not stable. The The methods which give good agreement with the data are selected.

  15. Adjunctive levetiracetam in children, adolescents, and adults with primary generalized seizures: Open-label, noncomparative, multicenter, long-term follow-up study.

    LENUS (Irish Health Repository)

    Delanty, Norman

    2012-02-01

    Purpose: To evaluate the long-term efficacy and tolerability of adjunctive levetiracetam (LEV) in patients with uncontrolled idiopathic generalized epilepsy (IGE). Methods: This phase III, open-label, long-term, follow-up study (N167; NCT00150748) enrolled patients (4 to <65 years) with primary generalized seizures (tonic-clonic, myoclonic, absence). Patients received adjunctive LEV at individualized doses (1,000-4,000 mg\\/day; 20-80 mg\\/kg\\/day for children\\/adolescents weighing <50 kg). Efficacy results are reported for all seizure types [intention-to-treat (ITT) population, N = 217] and subpopulations with tonic-clonic (n = 152), myoclonic (n = 121), and\\/or absence (n = 70) seizures at baseline. Key Findings: One hundred twenty-five (57.6%) of 217 patients were still receiving treatment at the end of the study. Mean (standard deviation, SD) LEV dose was 2,917.5 (562.9) mg\\/day. Median (Q1-Q3) exposure to LEV was 2.1 (1.5-2.8) years, and the maximum duration was 4.6 years. Most patients were taking one (124\\/217, 57.1%) or >\\/=2 (92\\/217, 42.4%) concomitant antiepileptic drugs (AEDs). Seizure freedom of >\\/=6 months (all seizure types; primary efficacy end point) was achieved by 122 (56.2%) of 217 patients, and 49 (22.6%) of 217 patients had complete seizure freedom. Seizure freedom of >\\/=6 months from tonic-clonic, myoclonic, and absence seizures was achieved by 95 (62.5%) of 152, 75 (62.0%) of 121, and 44 (62.9%) of 70 patients, respectively. Mean (SD) maximum seizure freedom duration was 371.7 (352.4) days. At least one treatment-emergent adverse event (TEAE) was reported by 165 (76%) of 217 patients; most TEAEs were mild\\/moderate in severity, with no indication of an increased incidence over time. Seventeen (7.8%) of 217 patients discontinued medication because of TEAEs. The most common psychiatric TEAEs were depression (16\\/217, 7.4%), insomnia (9\\/217, 4.1%), nervousness (8\\/217, 3.7%), and anxiety (7\\/217, 3.2%). Significance: Adjunctive

  16. Ca2+-DEPENDENT PROTEIN KINASE C ISOFORMS ARE CRITICAL TO ESTRADIOL 17β-D-GLUCURONIDE-INDUCED CHOLESTASIS IN THE RAT

    OpenAIRE

    Crocenzi, Fernando A.; Enrique J Sánchez Pozzi; Ruiz, María Laura; Zucchetti, Andrés E.; Roma, Marcelo G.; Mottino, Aldo D.; Vore, Mary

    2008-01-01

    The endogenous estradiol metabolite estradiol 17β-D-glucuronide (E217G) induces an acute cholestasis in rat liver coincident with retrieval of the canalicular transporters Bsep (Abcc11) and Mrp2 (Abcc2) and their associated loss of function. We assessed the participation of Ca2+-dependent PKC isoforms (cPKC) in the cholestatic manifestations of E217G in the perfused rat liver (PRL) and in isolated rat hepatocyte couplets (IRHC). In the PRL, E217G (2 μmol/liver; intraportal, single injection) ...

  17. Origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department); Origine des elements de la famille de l'uranium-235 observes dans la riviere Ellez a proximite du reacteur nucleaire experimental EL4 en cours de demantelement (Mont d'Arree - departement du Finistere). Resultats et premiers constats annee 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 ({sup 227}Ac), non born by its ascendents which are {sup 235}U and {sup 231}Pa is observed. This phenomenon is characterized by mass activities superior to these ones of {sup 235}U and able to reach these ones of {sup 238}U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil ({sup 210}Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  18. origin of elements of the Uranium-235 family observed in the Ellez river near the EL-4 experimental nuclear reactor in dismantling (Monts d'Arree- Finistere department)

    International Nuclear Information System (INIS)

    In a previous study which concerned the catchment basin of the harbour of Brest, the A.C.R.O. put in evidence a marking by artificial radioelements around the power plant of Brennilis which can be imputed without ambiguities to the nuclear installation. It also put in evidence abnormalities concerning the natural radioactivity which justifies this new study. In the area of the Monts d'Arree, actinium 227 (227Ac), non born by its ascendents which are 235U and 231Pa is observed. This phenomenon is characterized by mass activities superior to these ones of 235U and able to reach these ones of 238U. Its presence corresponds with the drainage of the Ellez river since the former channel of radioactive effluents releases from the nuclear power plant EL-4 up to the reservoir Saint-Herblot situated 6 km downstream. The strongest values of radioactivity are registered near the disused power plant, at this place a relationship exists between the level of actinium 227 and this one of the artificial radioactivity as it exists a relationship with the decay products of radon exhaled from the subsoil (210Pb). But its presence is not limited to a part of the Ellez river, it is equally observed in terrestrial medium, in places in priori not influenced by the direct liquid effluents of the power plant. This place is situated at more than 4 km and without any connection with the Ellez waters. At this stage of the study, it is not possible to answer with certainty the question of the origin of this phenomenon. A new reorientation is considered indispensable to clarify definitively the origin of this unknown phenomenon in the scientific publications and the environmental monitoring. (N.C.)

  19. 两种稀土产品中放射性核素分析研究%ANALYSIS OF RADIONUCLIDES IN TWO RARE EARTH PRODUCTS

    Institute of Scientific and Technical Information of China (English)

    周程; 孙恋君

    2009-01-01

    利用高纯锗γ谱仪对两个稀土产品氯化镧和氯化钇的样品进行能谱分析,研究经湿法冶炼工艺后的稀土产品中放射性核素的活度变化.结果表明,样品中存在天然放射性钍系和锕-铀系的核素,以及天然放射性核素~(138)La和~(176)Lu,但两个样品中所含的放射性核素不相同.氯化镧产品中锕-铀系和钍系核素放射性未达平衡,其主要子体~(224)Ra和~(227)Th的含量随时间发生明显变化,约60天达到平衡;而氯化钇产品没有这种现象.%This paper describes a study on raidoactivity change of rare-earth products after hydrometallurgy technology,using HPGe gamma spectrometer to analyze two rare earth products (LaCl_3 and YCl_3).The results show that in the two samples exist natural radionuclides of thorium series and actinium-uranium series as well as other natural radionuclides 138 La and 176 Lu.In the sample of lanthanum chloride the radioactivity of actinium-uranium series and thorium series has not reached balance,the contents of their main progenies ~(226)Ra and ~(227)Th obviously changes with the time,reaching balance 60 days later,while YCl_3 keeps stability.

  20. 50 CFR 660.15 - Equipment requirements.

    Science.gov (United States)

    2010-10-01

    .... (i) A personal computer with Pentium 75-MHz or higher. Random Access Memory (RAM) must have... application and available hard disk space of 217 MB or greater. A CD-ROM drive with a Video Graphics...

  1. Field Plot and Observation Points for Dinosaur National Monument Vegetation Mapping Project

    Data.gov (United States)

    National Park Service, Department of the Interior — This point file displays the 727 vegetation plots and 217 observation points visited in 2002, 2003 and 2004 as part of the vegetation mapping project. Plots and...

  2. Data of evolutionary structure change: 1GCVA-1YGDD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GCVA-1YGDD 1GCV 1YGD A D -AFTACEKQTIGKIAQVLAKSPEAYGAECLARLFVTHPG...R MHLTPEEKSAVTALWGKV--NVDEVGGEALGRLLVVYPETQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSEL... 217 ALA CA 203 LYS CA 239 1YGD D 1YGDD FGDLSTPDAVMGNPK THR CA 284 1YGD D 1YGD

  3. Protein (Cyanobacteria): 433086 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available antitermination protein NusG Prochlorococcus marinus str. MIT 9312 MSNELTTNLASSKANTSIARWYAVQVASSCEKKVKATLEQR...YP_396705.1 1117:25313 1212:957 1217:957 1218:957 1219:957 74546:217 transcription

  4. BIOMASS, SPECIES IDENTIFICATION, SPECIES IDENTIFICATION - LIFE STAGE, TAXONOMIC CODE and species abundance tows data collected in the Gulf of Alaska on the ALPHA HELIX and WECOMA cruises HX201, HX203 and others as part of the NEP project from 1997-10-14 to 2004-10-08 (NODC Accession 0113956)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113956 includes tows and biological data collected aboard the ALPHA HELIX and WECOMA during cruises HX201, HX203, HX205, HX208, HX211, HX215, HX217,...

  5. BIOMASS, SPECIES IDENTIFICATION, TAXONOMIC CODE, SPECIES IDENTIFICATION - LIFE STAGE and species abundance tows data collected in the Gulf of Alaska on the ALPHA HELIX and WECOMA cruises HX201, HX203 and others as part of the NEP project from 1997-10-10 to 2004-10-07 (NODC Accession 0113896)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0113896 includes tows and biological data collected aboard the ALPHA HELIX and WECOMA during cruises HX201, HX203, HX205, HX208, HX211, HX215, HX217,...

  6. La violencia, el Estado y las clases sociales

    Directory of Open Access Journals (Sweden)

    Gonzalo Sánchez Gómez

    2011-12-01

    Full Text Available Violencia, Conflicto y Politica en Colombia,Paul Oquist. Ed. Instituto de Estudios Colombianos Biblioteca Banco Popular; Bogota, 1978; 339 pags. / Violencia y Desarrollo, Darlo Fajardo. Fondo Editorial Suramerica, Bogota, 1979; 217 paga.

  7. 76 FR 8378 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2011-02-14

    ..., Richard, House, 3420 Richmond Ave, Mattoon, 11000030 Cook County Brown, Roger, Home and Studio, 1926 N... County Telluride House, 217 West Ave, Ithaca, 11000042 Westchester County Booth, Evangeline, House, 101...

  8. 26 CFR 31.3306(b)(9)-1 - Moving expenses.

    Science.gov (United States)

    2010-04-01

    ... expenses. (a) The term “wages” does not include remuneration paid on or after November 1, 1964, to or on... director or the courts finally to establish that a deduction is allowable under section 217. The...

  9. Reference: IDRSZMFER1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available tial involvement of the IDRS cis-element in the developmental and environmental regulation of the AtFer1 ferritin gene from Arabidopsis. Planta. 217: 709-716 (2003) PubMed: 12728319 ...

  10. 日本における恋愛研究の動向

    OpenAIRE

    立脇, 洋介; 松井, 豊; 比嘉, さやか

    2005-01-01

    In this study, we review 217 Japanese articles about romantic love. Most of the articles are based on questionnaires completed by university students, and fall within the domain of social psychology. The following shifts in Japanese ...

  11. Drug: D00251 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 217.2853 D00251.gif Antihypertensive; Enzyme inhibitor [angiotensin-converting] Therapeutic category: 2144 ...category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardiovascular agents 214 Antihypertensive

  12. Drug: D03328 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03328 Drug Carperitide (genetical recombination) (JAN); Carperitide (USAN/INN); Ha...l organs 21 Cardiovascular agents 217 Vasodilators 2179 Others D03328 Carperitide (genetical recombination)

  13. EST Table: CK514954 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Protein effet... (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum] FS793905 swj ...

  14. EST Table: FS879118 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available milar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Protein effet...se) (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum] FS793905 ftes ...

  15. EST Table: CK544577 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to Ubiquitin-conjugating enzyme E2-17 kDa (Ubiquitin-protein ligase) (Ubiquitin carrier protein) (Protein effet... (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum] FS793905 swh ...

  16. Teadlasena poliitikas - võimalused ja piirid = Als Wissenschaftler in der Politik - Chancen und Grenzen / Eiki Berg

    Index Scriptorium Estoniae

    Berg, Eiki, 1970-

    2005-01-01

    Autori hinnangul lasub teadlasel poliitikas suurem vastutus kui mistahes valdkonna esindajal, sest teaduslikult argumenteeritud poliitilised otsused on teadmiste jõu ja poliitilise võimu sümbioos. Vt. ka kommentaare lk. 217-222,467-472

  17. A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity

    OpenAIRE

    Kim, Dong-Hyun; Xiao, Zhen; Kwon, Sanghoon; Sun, Xiaoxiao; Ryerson, Daniel; Tkac, David; Ma, Ping; Wu, Shwu-Yuan; Chiang, Cheng-Ming; Zhou, Edward; Xu, H. Eric; Palvimo, Jorma J; Chen, Lin-Feng; Kemper, Byron; Kemper, Jongsook Kim

    2014-01-01

    Acetylation of transcriptional regulators is normally dynamically regulated by nutrient status but is often persistently elevated in nutrient-excessive obesity conditions. We investigated the functional consequences of such aberrantly elevated acetylation of the nuclear receptor FXR as a model. Proteomic studies identified K217 as the FXR acetylation site in diet-induced obese mice. In vivo studies utilizing acetylation-mimic and acetylation-defective K217 mutants and gene expression profilin...

  18. Immunization against Egyptian Schistosoma mansoni infection by multivalent DNA vaccine

    Institute of Scientific and Technical Information of China (English)

    Mahmoud H Romeih; Hanem M Hassan; Tarek S Abou Shousha; Mohamed A Saber

    2008-01-01

    The development of multivalent vaccines consisting of several antigens is a novel approach to creating broad-range protection against different parasite strains and parasite life cycle stages. We have previously confirmed that the schistosome Sm21.7 and SmFimbrin (SmFim) proteins could induce protection in mice. Therefore, this study aimed to construct the multivalent DNA vaccine Sm21.7-SmFim/pBudCE4.1 and evaluate its immune efficacy. The open reading frames of two Schistosoma mansoni genes, Sm21.7 and SmFim, were inserted into the eukaryotic expression plasmid pBudCE4.1 designed for the independent expression of two genes in mammalian cells. To evaluate the in vitro expression of the multivalent Sm21.7-SmFim/pBudCE4.1 DNA vaccine and its immunological effect in mice, the recombinant plasmid Sm21.7-SmFim/pBudCE4.1 was used to transfect 293T cells, and the expression of mRNA and proteins was examined using reverse transcription-polymerase chain reaction and Western blot analysis. Then the ability of Sm21.7.SmFim/pBudCE4.1 to protect against S. mansoni challenge infections was analyzed according to worm burden and egg reduction rates after vaccination of mice. Vaccinated mice showed a significant level of protection (56%), and a decrease in the number and size, and change in the cellular profile, of granulomas. Egg reduction in liver and intestine was 41.53% and 55.63%,respectively, as determined relative to mice that received the empty vector only. In addition to reductions in worm viability,worm fecundity and egg hatching ability were observed following challenge infection in the immunized group.Results showed that Sm21.7-SmFim/pBudCE4.1 could express Sm 21.7 and SmFim mRN A and proteins. Enzyme-linked immunosorbent assay and Western blot analysis indicated that immunized mice generated specific immunoglobulin G against Sm21.7-SmFim/pBudCE4.1. These results suggest that vaccination with multivalent S. mansoni DNA vaccine (SmFim-Sm21.7/pBudCE4.1) not only induces a

  19. Minor Actinide Burning in Thermal Reactors. A Report by the Working Party on Scientific Issues of Reactor Systems

    International Nuclear Information System (INIS)

    The actinides (or actinoids) are those elements in the periodic table from actinium upwards. Uranium (U) and plutonium (Pu) are two of the principal elements in nuclear fuel that could be classed as major actinides. The minor actinides are normally taken to be the triad of neptunium (Np), americium (Am) and curium (Cm). The combined masses of the remaining actinides (i.e. actinium, thorium, protactinium, berkelium, californium, einsteinium and fermium) are small enough to be regarded as very minor trace contaminants in nuclear fuel. Those elements above uranium in the periodic table are known collectively as the transuranics (TRUs). The operation of a nuclear reactor produces large quantities of irradiated fuel (sometimes referred to as spent fuel), which is either stored prior to eventual deep geological disposal or reprocessed to enable actinide recycling. A modern light water reactor (LWR) of 1 GWe capacity will typically discharge about 20-25 tonnes of irradiated fuel per year of operation. About 93-94% of the mass of uranium oxide irradiated fuel is comprised of uranium (mostly 238U), with about 4-5% fission products and ∼1% plutonium. About 0.1-0.2% of the mass is comprised of neptunium, americium and curium. These latter elements accumulate in nuclear fuel because of neutron captures, and they contribute significantly to decay heat loading and neutron output, as well as to the overall radio-toxic hazard of spent fuel. Although the total minor actinide mass is relatively small - approximately 20-25 kg per year from a 1 GWe LWR - it has a disproportionate impact on spent fuel disposal, and thus the longstanding interest in transmuting these actinides either by fission (to fission products) or neutron capture in order to reduce their impact on the back end of the fuel cycle. The combined masses of the trace actinides actinium, thorium, protactinium, berkelium and californium in irradiated LWR fuel are only about 2 parts per billion, which is far too low for

  20. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    International Nuclear Information System (INIS)

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  1. TRASH TO TREASURE: CONVERTING COLD WAR LEGACY WASTE INTO WEAPONS AGAINST CANCER

    Energy Technology Data Exchange (ETDEWEB)

    Nicholas, R.G.; Lacy, N.H.; Butz, T.R.; Brandon, N.E.

    2004-10-06

    As part of its commitment to clean up Cold War legacy sites, the U.S. Department of Energy (DOE) has initiated an exciting and unique project to dispose of its inventory of uranium-233 (233U) stored at Oak Ridge National Laboratory (ORNL), and extract isotopes that show great promise in the treatment of deadly cancers. In addition to increasing the supply of potentially useful medical isotopes, the project will rid DOE of a nuclear concern and cut surveillance and security costs. For more than 30 years, DOE's ORNL has stored over 1,200 containers of fissile 233U, originally produced for several defense-related projects, including a pilot study that looked at using 233U as a commercial reactor fuel. This uranium, designated as special nuclear material, requires expensive security, safety, and environmental controls. It has been stored at an ORNL facility, Building 3019A, that dates back to the Manhattan Project. Down-blending the material to a safer form, rather than continuing to store it, will eliminate a $15 million a year financial liability for the DOE and increase the supply of medical isotopes by 5,700 percent. During the down-blending process, thorium-229 (229Th) will be extracted. The thorium will then be used to extract actinium-225 (225Ac), which will ultimately supply its progeny, bismuth-213 (213Bi), for on-going cancer research. The research includes Phase II clinical trials for the treatment of acute myelogenous leukemia at Sloan-Kettering Memorial Cancer Center in New York, as well as other serious cancers of the lungs, pancreas, and kidneys using a technique known as alpha-particle radioimmunotherapy. Alpha-particle radioimmunotherapy is based on the emission of alpha particles by radionuclides. 213Bi is attached to a monoclonal antibody that targets specific cells. The bismuth then delivers a high-powered but short-range radiation dose, effectively killing the cancerous cells but sparing the surrounding tissue. Production of the actinium and

  2. 先天性巨结肠及其类缘病的临床病理学分析%Hirschsprung's disease and its allied diseases: a clinicopathologic analysis

    Institute of Scientific and Technical Information of China (English)

    杨军; 刘妮; 康安静; 陈晓黎; 靳耀锋; 苏宝山; 黄莺

    2012-01-01

    目的 回顾性分析先天性巨结肠症(HD)及其类缘病(HAD)的组织病理学特征.方法 按照HD和HAD病理诊断标准,回顾性分析217例临床诊断为巨结肠患者的病理切片.进行病理学诊断.结果 217例临床诊断为巨结肠的病例中,典型HD仅占41.47% (90/217),男女比例为8∶1;HAD占58.53%(127/217),男女比例为2.85∶1.结论 按照HD和HAD病理学诊断标准,临床上表现为巨结肠的患儿中58.53%的病例为HAD,HAD与HD患儿男女比例明显不同,提示两者可能具有不同的发病机制.%Objective To investigate clinical and histopathological characteristics of Hirschsprung's disease (HD) and HD allied disease (HAD) by a retrospective analysis.Methods Records of 217 cases clinical diagnosed as megacolon were retrospectively analyzed according to the standard for HD and HAD pathologic diagnosis.Results Among the 217 cases, 90 (41. 47% ) cases were typical HD, and the sex ratio was 8: 1 ;. 127 (58. 53% ) cases were HAD, and the sex ratio was of 2. 85: 1. Conclusion Totally 58. 53% of cases are HAD in the cases clinically diagnosed as megacolon. At the same time, HAD cases have a different sex ratio from typical HD case, suggesting that they may have a different pathogenesis.

  3. Culture of bovine embryos in polyester mesh sections: the effect of pore size and oxygen tension on in vitro development.

    Science.gov (United States)

    Somfai, T; Inaba, Y; Aikawa, Y; Ohtake, M; Kobayashi, S; Akai, T; Hattori, H; Konishi, K; Imai, K

    2010-12-01

    The purpose of this study was to assess the feasibility of polyester mesh culture for the in vitro production of bovine embryos, as polyester mesh is an alternative way for tracking individual embryos throughout culture using time-lapse cinematography (TLC). Bovine embryos were isolated during in vitro culture using sections of three different polyethylene terephthalate (PET) mesh products. In vitro matured and fertilized bovine oocytes were cultured in the 217 × 217, 230 × 230 or 238 × 238-μm openings of PET mesh sections or in simple micro-drops (control) for 7 days under either 20% or 5% O(2) tensions. No difference in embryo developmental rates was found between the culture groups in terms of cleavage, blastocyst formation and blastocyst expansion irrespective of O(2) tension. In contrast, under 20% O(2) tension, blastocysts that developed in PET mesh with 217 × 217-μm opening had significantly higher numbers of total and trophectoderm (TE) cells than control embryos; however, the numbers and proportions of inner cell mass (ICM) cells did not differ. Under 5% O(2) tension, no difference was found among the culture groups in the numbers of total, ICM and TE cells in embryos. All three PET mesh products investigated in this study were proven to be effective to prevent embryo movement. The results demonstrate that bovine embryos can be cultured in PET mesh sections without negative side-effects and suggest that embryo distance determined by the mesh affects embryo quality at atmospheric oxygen tension. Polyethylene terephthalate mesh with 217 × 217-μm openings was found to be the most suitable for further application in TLC. PMID:19845884

  4. Indice botánico

    OpenAIRE

    2015-01-01

    Achiote: 91, 94, 198 Aguaje: 156 Aji: 59, 74, 171 Alamo: 171 Algodón: 94, 110, 124 Aliso: 52 Alnus acuminata: ver aliso Aloes: 171 Altramuce: 44 Arachis hypogaea: ver maní Arracacha esculenta: 69 Arveja: 74 Asaí: ver palmera Bactris gasipaes: 141 Balsa palo de: 180 Befaría ledifolia: 64 Bertholetia excelsa: 154 Bixa orellana: ver achiote Bombax: 178 Bombonax: ver palmera Barbasco: 199 Cabeza de negro: ver Humiro Cacao: 194, 217 Café: 175, 179, 217 Camote: 62, 69, 74, 97, 182, 192 Caña de azúc...

  5. Reseñas de Libros

    OpenAIRE

    Daniel Alcalde Güelfo; Mª Candelaria Fuentes Navarro; Karl J. Trybus; Flavia Pascariello; Alfonso Pinilla García; David Molina Rabadán; Jan Nelis; José Joaquín Fernández Alles; Antonio J. Piqueres Díez

    2009-01-01

    Achcar, Gilbert, El choque de barbaries, terrorismo y desorden mundial. Barcelona, Icaria-Antrazyt, 2007, 197 pp.Páginas 213-214Daniel Alcalde GüelfoDel Arco Blanco, Miguel Ángel, Hambre de Siglos. Mundo rural y apoyos sociales del franquismo en Andalucía Oriental (1936-1951). Granada, Comares Historia, 2007, 513 pp.Páginas 214-217Mª Candelaria Fuentes NavarroBen-Ghiat, Ruth; Fuller, Mia (eds.), Italian Colonialism. New York, Palgrave MacMillan, 2005, 266 pp.Páginas 217-219Karl J. TrybusBlack...

  6. Drug: D01573 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01573 Drug Etilefrine hydrochloride (JP16); Etilefrine hydrochloride (TN) C10H15NO...2. HCl 217.087 217.6925 D01573.gif Antihypotensive; Sympathomimetic Therapeutic category: 2119 ATC code: C01CA01 alpha1-adr...tion hsa04270(146+147+148) Vascular smooth muscle contraction hsa04970(146+147+148) Salivary secretion Therapeutic category of dr... 211 Cardiotonics 2119 Others D01573 Etilefrine hydrochloride (JP16) Anatomical T...AC STIMULANTS EXCL. CARDIAC GLYCOSIDES C01CA Adrenergic and dopaminergic agents C01CA01 Etilefrine D01573 Etilefrine hydr

  7. 76 FR 20080 - Inventory of U.S.-Flag Launch Barges

    Science.gov (United States)

    2011-04-11

    ...Dermott Tidelands 021 J. Ray McDermott, Inc 1980 240 72 4,700 2,200 X McDermott Tidelands No. 012 J. Ray McDermott, Inc 1973 240 72.2 4,217 4,000 X McDermott Tidelands No. 014 J. Ray McDermott, Inc 1973 240 72.2 4,217 4,000 X McDermott Tidelands 020 J. Ray McDermott, Inc 1980 240 72 5,186 5,000 X...

  8. Diethylstilbestrol can effectively accelerate estradiol-17-O-glucuronidation, while potently inhibiting estradiol-3-O-glucuronidation

    International Nuclear Information System (INIS)

    This in vitro study investigates the effects of diethylstilbestrol (DES), a widely used toxic synthetic estrogen, on estradiol-3- and 17-O- (E2-3/17-O) glucuronidation, via culturing human liver microsomes (HLMs) or recombinant UDP-glucuronosyltransferases (UGTs) with DES and E2. DES can potently inhibit E2-3-O-glucuronidation in HLM, a probe reaction for UGT1A1. Kinetic assays indicate that the inhibition follows a competitive inhibition mechanism, with the Ki value of 2.1 ± 0.3 μM, which is less than the possible in vivo level. In contrast to the inhibition on E2-3-O-glucuronidation, the acceleration is observed on E2-17-O-glucuronidation in HLM, in which cholestatic E2-17-O-glucuronide is generated. In the presence of DES (0–6.25 μM), Km values for E2-17-O-glucuronidation are located in the range of 7.2–7.4 μM, while Vmax values range from 0.38 to 1.54 nmol/min/mg. The mechanism behind the activation in HLM is further demonstrated by the fact that DES can efficiently elevate the activity of UGT1A4 in catalyzing E2-17-O-glucuronidation. The presence of DES (2 μM) can elevate Vmax from 0.016 to 0.81 nmol/min/mg, while lifting Km in a much lesser extent from 4.4 to 11 μM. Activation of E2-17-O-glucuronidation is well described by a two binding site model, with KA, α, and β values of 0.077 ± 0.18 μM, 3.3 ± 1.1 and 104 ± 56, respectively. However, diverse effects of DES towards E2-3/17-O-glucuronidation are not observed in liver microsomes from several common experimental animals. In summary, this study issues new potential toxic mechanisms for DES: potently inhibiting the activity of UGT1A1 and powerfully accelerating the formation of cholestatic E2-17-O-glucuronide by UGT1A4. - Highlights: • E2-3-O-glucuronidation in HLM is inhibited when co-incubated with DES. • E2-17-O-glucuronidation in HLM is stimulated when co-incubated with DES. • Acceleration of E2-17-O-glucuronidationin in HLM by DES is via activating the activity of UGT1A4

  9. 78 FR 78508 - Quarterly Rail Cost Adjustment Factor

    Science.gov (United States)

    2013-12-26

    ...-inclusive index of railroad input prices ] and the method for computing the rail cost adjustment factor... 208.7 5 DEPRECIATION 11.9 221.0 217.8 6 INTEREST 2.0 76.6 76.6 7 OTHER ITEMS \\2\\ 21.9 220.0 220.5 8... EQUIPMENT RENTS 5.6 208.0 207.6 5 DEPRECIATION 11.5 218.9 217.8 6 INTEREST 2.3 87.3 87.3 7 OTHER ITEMS...

  10. Physical Activity

    DEFF Research Database (Denmark)

    Andersen, Lars Bo; Anderssen, Sigmund Alfred; Wisløff, Ulrik;

    2014-01-01

    Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers.......Andersen LB, Anderssen SA, Wisløff U, Hellénius M-L, Fogelholm M, Ekelund U. (Expert Group) Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. Chapter: Physical Activity p. 195-217.Nordic Counsil of Ministers....

  11. Formerly utilized MED/AEC sites remedial action program. Radiological survey of the E. I. Du Pont de Nemours and Co. , Deepwater, New Jersey. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-12-01

    The results of a radiological survey of the E. I. Du Pont Company, Deepwater, New Jersey, are presented in this report. During the 1940's this site was used for development of a process for the conversion of uranium oxide to produce uranium tetrafluoride and small quantities of uranium metal. The survey included measurements of the following: residual alpha and beta--gamma contamination levels, both fixed and transferable, in the one remaining uranium tetrafluoride operations building; external gamma radiation levels at 1 m above the surface inside this building and at outdoor locations where radioactive materials were handled; radon and radon daughter concentrations in the air in the operations building; uranium, radium, actinium, and thorium concentrations in soil and water on and near the site; and the airborne concentrations of uranium, thorium, and radium in the operations building. Elevated concentrations of uranium were found in residues from the operations building and in some surface and subsurface soil samples. Alpha and beta--gamma contamination levels in some areas of the operations building were above the limits of current federal guidelines set for the release of property for unrestricted use. 18 figures, 11 tables.

  12. Ac, La, and Ce radioimpurities in {sup 225}Ac produced in 40-200 MeV proton irradiations of thorium

    Energy Technology Data Exchange (ETDEWEB)

    Engle, Jonathan W.; Ballard, Beau D. [Los Alamos National Laboratory, NM (United States); Weidner, John W. [Air Force Institute of Technology, Wright Patterson Air Force Base, OH (United States); and others

    2014-10-01

    Accelerator production of {sup 225}Ac addresses the global supply deficiency currently inhibiting clinical trials from establishing {sup 225}Ac's therapeutic utility, provided that the accelerator product is of sufficient radionuclidic purity for patient use. Two proton activation experiments utilizing the stacked foil technique between 40 and 200 MeV were employed to study the likely co-formation of radionuclides expected to be especially challenging to separate from {sup 225}Ac. Foils were assayed by nondestructive γ-spectroscopy and by α-spectroscopy of chemically processed target material. Nuclear formation cross sections for the radionuclides {sup 226}Ac and {sup 227}Ac as well as lower lanthanide radioisotopes {sup 139}Ce, {sup 141}Ce, {sup 143}Ce, and {sup 140}La whose elemental ionic radii closely match that of actinium were measured and are reported. The predictions of the latest MCNP6 event generators are compared with measured data, as they permit estimation of the formation rates of other radionuclides whose decay emissions are not clearly discerned in the complex spectra collected from {sup 232}Th(p,x) fission product mixtures. (orig.)

  13. Pulse-shape discrimination and energy quenching of alpha particles in Cs$_2$LiLaBr$_6$:Ce$^{3+}$

    CERN Document Server

    Mesick, Katherine E; Stonehill, Laura C

    2016-01-01

    Cs$_2$LiLaBr$_6$:Ce$^{3+}$ (CLLB) is an elpasolite scintillator that offers excellent linearity and gamma-ray energy resolution and sensitivity to thermal neutrons with the ability to perform pulse-shape discrimination (PSD) to distinguish gammas and neutrons. Our investigation of CLLB has indicated the presence of intrinsic radioactive alpha background that we have determined to be from actinium contamination of the lanthanum component. We measured the pulse shapes for gamma, thermal neutron, and alpha events and determined that PSD can be performed to separate the alpha background with a moderate figure of merit of 0.98. We also measured the electron-equivalent-energy of the alpha particles in CLLB and simulated the intrinsic alpha background from $^{227}$Ac to determine the quenching factor of the alphas. A linear quenching relationship $L_{\\alpha} = E_{\\alpha} \\times q + L_0$ was found at alpha particle energies above 5 MeV, with a quenching factor $q = 0.71$ MeVee/MeV and an offset $L_0 = - 1.19$ MeVee.

  14. An Ion Exchange Study of Possible Hydridized 5f Bonding in theActinides

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, R.M.; Street, Jr., K.; Seaborg, G.T.

    1951-08-28

    A study has been made of the elution behavior of curium(III), americium(III), plutonium(III), actinium(III), plutonium(IV), neptunium(IV), uraniuM(IV), thorium(IV), neptunium(V), plutonium (VI), uranium (VI), lanthanum(III), cerium(III), europium(III), ytterbium(III), ytterium(III), strontium(II), barium(II), radium(II), cesium(I) with 3.2 M, 6.2 M, 9.3 M, and 12.2 M HCl solutions from Dowex-50 cation exchange resin columns. These elutions show that in high concentrations of hydrochloric acid the actinides form complex ions with chloride ion to a much greater extent than the lanthanides. The strengths of the tripositive actinide complex ions apparently go in the order plutonium > americium> curium, although their ionic radii also decrease in this same order. To explain these results, a partial covalent character may be ascribed to the bonding in the transuranium complex ions. It is shown that a reasonable structure for such covalent bonding involves hybridization of the 5f orbitals in the actinide elements.

  15. Extending the north-east limit of the chart of nuclides

    CERN Document Server

    Benlliure, J; Kurtukian-Nieto, T; Schmidt, K -H; Audouin, L; Blank, B; Becker, F; Casarejos, E; Cortina-Gil, D; Enqvist, T; Fernández, B; Fernández-Ordóñez, M; Giovinazzo, J; Henzlova, D; Junghans, A R; Jurado, B; Napolitani, P; Pereira, J; Rejmund, F; Yordanov, O

    2010-01-01

    The existence of nuclei with exotic combinations of protons and neutrons provides fundamental information on the forces acting between nucleons. The maximum number of neutrons a given number of protons can bind, neutron drip line1, is only known for the lightest chemical elements, up to oxygen. For heavier elements, the larger its atomic number, the farther from this limit is the most neutron-rich known isotope. The properties of heavy neutron-rich nuclei also have a direct impact on understanding the observed abundances of chemical elements heavier than iron in our Universe. Above half of the abundances of these elements are thought to be produced in rapid-neutron capture reactions, r-process, taking place in violent stellar scenarios2 where heavy neutron-rich nuclei, far beyond the ones known up today, are produced. Here we present a major step forward in the production of heavy neutron-rich nuclei: the discovery of 73 new neutron-rich isotopes of chemical elements between tantalum (Z=72) and actinium (Z=89...

  16. Liquid Scintillation Counting of Environmental Radioisotopes: A Review of the Impact of Background Reduction

    Energy Technology Data Exchange (ETDEWEB)

    Douglas, Matthew; Bernacki, Bruce E.; Erchinger, Jennifer L.; Finn, Erin C.; Fuller, Erin S.; Hoppe, Eric W.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Orrell, John L.; Panisko, Mark E.; Warren, Glen A.; Wright, Michael E.

    2016-03-09

    Liquid scintillation counting (LSC) is a versatile and commonplace method for radiometric measurement of charged particle emitting radionuclides. The LSC method provides utility in a range of environmental science applications including hydrological studies of water transport, anthropogenic releases of radionuclides into the environment, and vertical mixing rates within oceans. Instrumental measurement background is one limiting factor of radiometric measurement sensitivity. As part of the development of a custom low background LSC system located in a shallow underground laboratory at Pacific Northwest National Laboratory, a number of measurement applications of LSC have been considered and are summarized here. The focus is on determining which aspects of such measurements would gain the greatest benefit from the reduction of LSC backgrounds by a factor of 10-100 relative to values reported in the literature. Examples of benefits include lowering the minimum detectable activity, reducing the sample size required, and shortening the elapsed timeline of the processing and analysis sequence. In particular tritium, strontium, and actinium isotopes are examined as these isotopes cover a range of requirements related to the LSC measurement method (e.g., 3H: low energy; Sr: spectral deconvolution; Ac: alpha/beta discrimination).

  17. Development of an Ultra-Low Background Liquid Scintillation Counter for Trace Level Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Erchinger, Jennifer L.; Orrell, John L.; Aalseth, Craig E.; Bernacki, Bruce E.; Douglas, Matthew; Finn, Erin C.; Fuller, Erin S.; Keillor, Martin E.; Morley, Shannon M.; Mullen, Crystal A.; Panisko, Mark E.; Shaff, Sarah M.; Warren, Glen A.; Wright, Michael E.

    2015-09-01

    Low-level liquid scintillation counting (LSC) has been established as one of the radiation detection techniques useful in elucidating environmental processes and environmental monitoring around nuclear facilities. The Ultra-Low Background Liquid Scintillation Counter (ULB-LSC) under construction in the Shallow Underground Laboratory at Pacific Northwest National Laboratory aims to further reduce the MDAs and/or required sample processing. Through layers of passive shielding in conjunction with an active veto and 30 meters water equivalent overburden, the background reduction is expected to be 10 to 100 times below typical analytic low-background liquid scintillation systems. Simulations have shown an expected background of around 14 counts per day. A novel approach to the light collection will use a coated hollow light guide cut into the inner copper shielding. Demonstration LSC measurements will show low-energy detection, spectral deconvolution, and alpha/beta discrimination capabilities, from trials with standards of tritium, strontium-90, and actinium-227, respectively. An overview of the system design and expected demonstration measurements will emphasize the potential applications of the ULB-LSC in environmental monitoring for treaty verification, reach-back sample analysis, and facility inspections.

  18. Purification of lanthanides for double beta decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Polischuk, O. G. [Institute for Nuclear Research, MSP 03680 Kyiv, Ukraine and INFN, Section of Rome, La Sapienza, I-00185 Rome (Italy); Barabash, A. S. [Institute of Theoretical and Experimental Physics, 117259 Moscow (Russian Federation); Belli, P. [INFN, Section of Rome Tor Vergata, I-00133 Rome (Italy); Bernabei, R. [INFN, Section of Rome Tor Vergata, I-00133 Rome, Italy and Department of Physics, University of Rome Tor Vergata, I-00133 Rome (Italy); Boiko, R. S.; Danevich, F. A.; Mokina, V. M.; Poda, D. V.; Tretyak, V. I. [Institute for Nuclear Research, MSP 03680 Kyiv (Ukraine); Cappella, F.; Incicchitti, A. [INFN, Section of Rome La Sapienza, I-00185 Rome, Italy and Department of Physics, University of Rome La Sapienza, I-00185 Rome (Italy); Cerulli, R.; Laubenstein, M.; Nisi, S. [INFN, Gran Sasso National Laboratories, I-67100 Assergi (Aq) (Italy)

    2013-08-08

    There are several potentially double beta active isotopes among the lanthanide elements. However, even high purity grade lanthanide compounds contain {sup 238}U, {sup 226}Ra and {sup 232,228}Th typically on the level of ∼ (0.1 - 1) Bq/kg. The liquid-liquid extraction technique was used to remove traces of U, Ra and Th from CeO{sub 2}, Nd{sub 2}O{sub 3} and Gd{sub 2}O{sub 3}. The radioactive contamination of the samples before and after the purification was tested by using ultra-low-background HPGe γ spectrometry at the underground Gran Sasso National Laboratories of the INFN (Italy). After the purification the radioactive contamination of gadolinium oxide by Ra and Th was decreased at least one order of magnitude. The efficiency of the approach to purify cerium oxide from Ra was on same level, while the radioactive contamination of neodymium sample before and after the purification is below the sensitivity of analytical methods. The purification method is much less efficient for chemically very similar radioactive elements like lanthanum, lutetium and actinium. R and D of the methods to remove the pollutions with improved efficiency is in progress.

  19. Radium-228 determination of natural waters via concentration on manganese dioxide and separation using Diphonix ion exchange resin.

    Science.gov (United States)

    Nour, S; El-Sharkawy, A; Burnett, W C; Horwitz, E P

    2004-12-01

    The objective of this work was to establish a new procedure for 228Ra determination of natural waters via preconcentration of radium on MnO2 and separation of its daughter, 228Ac, using Diphonix ion exchange resin. Following removal of potential interferences via passage through an initial Diphonix Resin column, the first daughter of 228Ra, 228Ac, is isolated by chromatographic separation via a second Diphonix column. A holding time of > 30 h for 228Ac ingrowth in between the two column separations ensures secular equilibrium. Barium-133 is used as a yield tracer. Actinium-228 is eluted from the second Diphonix Resin with 5 ml 1M 1-Hydroxyethane-1,1-diphosphonic acid (HEDPA) and quantified by addition of scintillation cocktail and LSC counting. Radium (and 133Ba) from the load and rinse solutions from the 2nd Diphonix column may be prepared for alpha spectrometry (for determination of 223Ra, 224Ra, and 226Ra) by BaSO4 microprecipitation and filtration. Decontamination tests indicate that U, Th, and Ra series nuclides do not interfere with these measurements, although high contents of 90Sr (90Y) require additional treatment for accurate measurement of 228Ra. Addition of stable Sr as a "hold back" carrier during the initial MnO2 preconcentration step was shown to remove most 90Sr interference.

  20. Soil and river sediments radionuclides monitoring at Aramar Experimental Center: an historical overview

    Energy Technology Data Exchange (ETDEWEB)

    Segre, Nadia; Fagundes, Rosane Correa, E-mail: nadia.segre@ctmsp.mar.mil.br [Centro Tecnologico da Marinha (CTM-SP/CEA/LARE), Ipero, SP (Brazil). Centro Experimental Aramar. Lab. Radioecologico; Moraes, Marco Antonio P.V. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    In order to evaluate possible effects to the environment resulting from the implementation of the Centro Tecnologico da Marinha - Centro Experimental Aramar (CTMSP-CEA) at Ipero in Sao Paulo state, Brazil, which came into operation in 1989, an Environmental Monitoring Program (PMA) was established in October, 1987. One of the aims of this program is to monitor the soil and river sediments radionuclides levels at CEA and beyond its boundary. The utilization of statistical tools to evaluate the results of radiometric environmental monitoring is a procedure required by National Nuclear Energy Commission (CNEN). The box plot is a simple statistical tool for displaying data. The central tendency and dispersion of the results as well as the observation of unusual results (outliers) in the dataset are easily visualized. Control chart is a graph that maps data and provides a picture of how a process is performing over time. A control chart always has a central line for the mean, an upper line for the upper control limit and a lower line for the lower control limit. Box plots and control charts were used to visualize the annual amount of natural uranium, lead-214, actinium-228 and lead-212 in soil and river sediment detected between 1987 and 2011, considering the measurements of all monitored places each year. This historical observation shows that, in average, the results obtained are below than the 1987-1988 levels (CEA's pre-operational) or below than the backgrounds radionuclides values. (author)

  1. Background radiation and individual dosimetry in the costal area of Tamil Nadu, India.

    Science.gov (United States)

    Matsuda, Naoki; Brahmanandhan, G M; Yoshida, Masahiro; Takamura, Noboru; Suyama, Akihiko; Koguchi, Yasuhiro; Juto, Norimichi; Raj, Y Lenin; Winsley, Godwin; Selvasekarapandian, S

    2011-07-01

    South coast of India is known as the high-level background radiation area (HBRA) mainly due to beach sands that contain natural radionuclides as components of the mineral monazite. The rich deposit of monazite is unevenly distributed along the coastal belt of Tamil Nadu and Kerala. An HBRA site that laid in 2×7 m along the sea was found in the beach of Chinnavillai, Tamil Nadu, where the maximum ambient dose equivalent reached as high as 162.7 mSv y(-1). From the sands collected at the HBRA spot, the high-purity germanium semi-conductor detector identified six nuclides of thorium series, four nuclides of uranium series and two nuclides belonging to actinium series. The highest radioactivity observed was 43.7 Bq g(-1) of Th-228. The individual dose of five inhabitants in Chinnavillai, as measured by the radiophotoluminescence glass dosimetry system, demonstrated the average dose of 7.17 mSv y(-1) ranging from 2.79 to 14.17 mSv y(-1).

  2. DISSOLVED CONCENTRATION LIMITS OF RADIOACTIVE ELEMENTS

    Energy Technology Data Exchange (ETDEWEB)

    NA

    2004-11-22

    The purpose of this study is to evaluate dissolved concentration limits (also referred to as solubility limits) of elements with radioactive isotopes under probable repository conditions, based on geochemical modeling calculations using geochemical modeling tools, thermodynamic databases, field measurements, and laboratory experiments. The scope of this modeling activity is to predict dissolved concentrations or solubility limits for 14 elements with radioactive isotopes (actinium, americium, carbon, cesium, iodine, lead, neptunium, plutonium, protactinium, radium, strontium, technetium, thorium, and uranium) important to calculated dose. Model outputs for uranium, plutonium, neptunium, thorium, americium, and protactinium are in the form of tabulated functions with pH and log (line integral) CO{sub 2} as independent variables, plus one or more uncertainty terms. The solubility limits for the remaining elements are either in the form of distributions or single values. The output data from this report are fundamental inputs for Total System Performance Assessment for the License Application (TSPA-LA) to determine the estimated release of these elements from waste packages and the engineered barrier system. Consistent modeling approaches and environmental conditions were used to develop solubility models for all of the actinides. These models cover broad ranges of environmental conditions so that they are applicable to both waste packages and the invert. Uncertainties from thermodynamic data, water chemistry, temperature variation, and activity coefficients have been quantified or otherwise addressed.

  3. A Critical Review of Alpha Radionuclide Therapy-How to Deal with Recoiling Daughters?

    Science.gov (United States)

    de Kruijff, Robin M; Wolterbeek, Hubert T; Denkova, Antonia G

    2015-01-01

    This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET). Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium), 223Ra, and 225Ac (actinium) can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue. PMID:26066613

  4. A Critical Review of Alpha Radionuclide Therapy—How to Deal with Recoiling Daughters?

    Science.gov (United States)

    de Kruijff, Robin M.; Wolterbeek, Hubert T.; Denkova, Antonia G.

    2015-01-01

    This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET). Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium), 223Ra, and 225Ac (actinium) can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue. PMID:26066613

  5. A Critical Review of Alpha Radionuclide Therapy—How to Deal with Recoiling Daughters?

    Directory of Open Access Journals (Sweden)

    Robin M. de Kruijff

    2015-06-01

    Full Text Available This review presents an overview of the successes and challenges currently faced in alpha radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared to beta or gamma radiation due to their short penetration depth and high linear energy transfer (LET. Touching briefly on the clinical successes of radionuclides emitting only one alpha particle, the main focus of this article lies on those alpha-emitting radionuclides with multiple alpha-emitting daughters in their decay chain. While having the advantage of longer half-lives, the recoiled daughters of radionuclides like 224Ra (radium, 223Ra, and 225Ac (actinium can do significant damage to healthy tissue when not retained at the tumour site. Three different approaches to deal with this problem are discussed: encapsulation in a nano-carrier, fast uptake of the alpha emitting radionuclides in tumour cells, and local administration. Each approach has been shown to have its advantages and disadvantages, but when larger activities need to be used clinically, nano-carriers appear to be the most promising solution for reducing toxic effects, provided there is no accumulation in healthy tissue.

  6. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  7. Tumor immunotargeting using innovative radionuclides.

    Science.gov (United States)

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  8. Rutherford's curriculum vitae, 1894-1907.

    Science.gov (United States)

    Cohen, M

    1995-06-01

    A single page, handwritten document was discovered when the Macdonald Physics building of McGill University in Montreal was gutted in 1978. This proved to be the draft of Ernest Rutherford's curriculum vitae (C.V.) covering the years 1894-1907, probably written in the autumn of 1906 when Rutherford was preparing to leave McGill. The C.V. contains 21 headings in chronological order, referring to research and other activities of Rutherford and his coauthors (especially Soddy and Barnes), plus a further set of headings relating to the associated investigations of Rutherford's team, including Eve and Hahn. A transcript of the document is provided, although in several places, Rutherford's handwriting is difficult to interpret, and the significance of his abbreviations is not always clear. Each of the items in the C.V. is discussed briefly in this review, in the light both of Rutherford's personal career and of the contribution of his team to the development and understanding of radioactivity. This contribution included the cause and nature of radioactivity (with Soddy), energy aspects of radioactive decay (with Barnes), elucidation of the uranium-radium, thorium and actinium series (Godlewski and Hahn), the radioactivity of the earth and atmosphere (Eve), the nature of the gamma rays (Eve) and, perhaps most important of all, the nature and properties of the alpha particle (Rutherford himself). The latter investigations led directly to Rutherford's later work in Manchester, including the nuclear model of the atom and artificial disintegration of the nucleus.

  9. Factors Affecting Spatial Test Performance: Sex, Handedness, Birth Order, and Experience.

    Science.gov (United States)

    Guay, Roland B.

    Four factors have been reported in the literature as being related to spatial test performance. This study investigated the main and interaction effects of sex, handedness, birth order, and experience on three different types of spatial performance; surface development, object rotation, and coordination of viewpoints. A total of 217 undergraduate…

  10. Time use of Hellene 3rd and 4th graders during a school day

    NARCIS (Netherlands)

    Vleioras, Georgios

    2010-01-01

    Using data from the time diaries of 164 Hellene 3rd and 4th graders interviewed in their homes in March 2007, individual differences in time-use patterns were investigated. The participants rested for 9 hours 10 minutes, and spent 57.0%, 21.7%, and 5.0% of their waking time on school-related activit

  11. Academic Inbreeding in the Portuguese Academia

    Science.gov (United States)

    Tavares, Orlanda; Cardoso, Sónia; Carvalho, Teresa; Sousa, Sofia Branco; Santiago, Rui

    2015-01-01

    This paper analyses the inbreeding phenomena in Portuguese public universities. Inbreeding is defined as the recruitment of academics by the same institution that awarded their PhDs. Focusing on 1,217 PhD-holding Portuguese academics, belonging to four public universities and to six disciplinary areas, inbreeding is analysed in order to understand…

  12. Coastal sensitivity mapping of Gulf of Kachchh and Gulf of Cambay, India

    Digital Repository Service at National Institute of Oceanography (India)

    ManiMurali, R.; Boora, P.; Vethamony, P.

    sq km. The intertidal biomass is very high at Vadinar and Sikka compared to Bedi and Okha. According to satellite data, the total reef area in the Gulf is 139.72 sq km. It has decreased from 217 sq km in 1975 to 139.7 sq km in 2011 which amounts to a...

  13. 36 CFR 9.32 - Access.

    Science.gov (United States)

    2010-07-01

    ... MANAGEMENT Non-Federal Oil and Gas Rights § 9.32 Access. (a) No access on, across or through lands or waters... CFR 2.17. (d) No access to a site outside a unit will be permitted across unit lands unless such access is by foot, pack animal, or designated road. Persons using designated roads for access to such...

  14. Komplikationer til langtidsbehandling med vitamin K-antagonister

    DEFF Research Database (Denmark)

    May, O; Garne, E; Mickley, H

    1990-01-01

    Long-term treatment with vitamin K antagonists (vKA) frequently involves complications. The commonest complication is haemorrhage and cases of serious haemorrhage are stated in the literature to occur with a frequency per 1,000 treatment years of 12-108, of which 2-17 are fatal. The majority...

  15. Projecting Continuing Student Enrolments: A Comparison of Approaches

    Science.gov (United States)

    Aitken, Robert; Young, Anne; McConkey, Kevin

    2011-01-01

    Higher education in Australia is undergoing a comprehensive reform with particular focus on higher levels of attainment by increasing access to university study for Australians from all backgrounds. To support the government's ambition of around 217,000 additional graduates by 2025, it has committed to removing caps and funding student places on…

  16. Randomized Controlled Trial of a Preventive Intervention for Perinatal Depression in High-Risk Latinas

    Science.gov (United States)

    Le, Huynh-Nhu; Perry, Deborah F.; Stuart, Elizabeth A.

    2011-01-01

    Objective: A randomized controlled trial was conducted to evaluate the efficacy of a cognitive-behavioral (CBT) intervention to prevent perinatal depression in high-risk Latinas. Method: A sample of 217 participants, predominantly low-income Central American immigrants who met demographic and depression risk criteria, were randomized into usual…

  17. 75 FR 41579 - Submitting Airline Data via the Internet

    Science.gov (United States)

    2010-07-16

    ..., traffic, operational, and consumer reports to BTS via the Internet on December 20, 2006, (71 FR 76226.... 12866: Regulatory and Planning Review Under Executive Order No. 12866, (58 FR 51735, October 4, 1993... Transportation 14 CFR Parts 217, 234, 241, et al. Submitting Airline Data via the Internet; Final Rule...

  18. 12 CFR Supplement I to Part 230 - Official Staff Interpretations

    Science.gov (United States)

    2010-01-01

    ... opened as a condition of obtaining a credit card iii. Accounts denominated in a foreign currency iv... agreements, interest rate swaps, and bankers acceptances (b) Advertisement 1. Covered messages... on demand accounts. (See 12 CFR § 217.2(d).) (p) Passbook savings account 1. Relation to Regulation...

  19. Dicty_cDB: Contig-U15405-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tugueseWaterDog Canis familiar... 44 0.80 1 ( BV312740 )...s troglodyt... 44 0.80 1 ( BV495481 ) S217P61918FE2.T0 Noemie Pan troglodytes troglodyt... 44 0.80 1 ( BV436248 ) S237P6495RF5.T0 Por

  20. Impact of a Community-Based Prevention Marketing Intervention to Promote Physical Activity among Middle-Aged Women

    Science.gov (United States)

    Sharpe, Patricia A.; Burroughs, Ericka L.; Granner, Michelle L.; Wilcox, Sara; Hutto, Brent E.; Bryant, Carol A.; Peck, Lara; Pekuri, Linda

    2010-01-01

    A physical activity intervention applied principles of community-based participatory research, the community-based prevention marketing framework, and social cognitive theory. A nonrandomized design included women ages 35 to 54 in the southeastern United States. Women (n = 430 preprogram, n = 217 postprogram) enrolled in a 24-week behavioral…

  1. Storytelling Slide Shows to Improve Diabetes and High Blood Pressure Knowledge and Self-Efficacy: Three-Year Results among Community Dwelling Older African Americans

    Science.gov (United States)

    Bertera, Elizabeth M.

    2014-01-01

    This study combined the African American tradition of oral storytelling with the Hispanic medium of "Fotonovelas." A staggered pretest posttest control group design was used to evaluate four Storytelling Slide Shows on health that featured community members. A total of 212 participants were recruited for the intervention and 217 for the…

  2. How well does journal 'impact' work in the assessment of papers on clinical physiology and nuclear medicine?

    DEFF Research Database (Denmark)

    Hansen, HB; Henriksen, Jens Henrik Sahl

    1997-01-01

    This study reports a citation analysis of 217 scientific papers on clinical physiology and nuclear medicine published in 69 different journals during the years 1985-92. The actual citation frequency was compared with the journal 'impact factor' (i.e. the average number of times a paper is cited i...

  3. 76 FR 16777 - Announcement of Meeting of the Secretary's Advisory Committee on National Health Promotion and...

    Science.gov (United States)

    2011-03-25

    ... efforts to implement the nation's health promotion and disease prevention objectives and strategies to... Promotion and Disease Prevention Objectives for 2020 AGENCY: Department of Health and Human Services, Office... Health Promotion. ACTION: Notice of meeting. Authority: 42 U.S.C. 217a, Section 222 of the Public...

  4. 76 FR 33764 - Announcement of Meeting of the Secretary's Advisory Committee on National Health Promotion and...

    Science.gov (United States)

    2011-06-09

    ... implement the nation's health promotion and disease prevention objectives and strategies to improve the... Promotion and Disease Prevention Objectives for 2020 AGENCY: Department of Health and Human Services, Office... Health Promotion. ACTION: Notice of Meeting. Authority: 42 U.S.C. 217a, Section 222 of the Public...

  5. 75 FR 37813 - Announcement of Meeting of the Secretary's Advisory Committee on National Health Promotion and...

    Science.gov (United States)

    2010-06-30

    ... health promotion and disease prevention objectives and strategies to improve the health status and reduce... Promotion and Disease Prevention Objectives for 2020 AGENCY: Department of Health and Human Services, Office... Promotion. ACTION: Notice of meeting. Authority: 42 U.S.C. 217a, Section 222 of the Public Health...

  6. Dicty_cDB: Contig-U16022-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available wanella denitrificans OS217, complete genome. 42 0.045 2 ( DY881365 ) AresSEQ10595 Amorphotheca resina...e pBluescript (Ec... 44 0.046 2 ( DY882832 ) AresSEQ12039 Amorphotheca resinae pBluescr

  7. Radiation damage of laser materials. Citations from the NTIS data base

    Science.gov (United States)

    Carrigan, B.

    1980-05-01

    Laser beam damage to laser materials such as optical glass, glass fibers, alkali metal halides, metals, mirrors, optical coatings, dielectrics, semiconductors, and matrix materials is studied. The majority of these citations concern infrared laser damage to infrared optical materials. This updated bibliography contains 217 abstracts, 10 of which are new entries to the previous edition.

  8. Synthesis and Physicochemical Properties of [19,20-13C]-17α-Ethinylestradiol

    NARCIS (Netherlands)

    Kraan, G.P.B.; Drayer, N.M.; Kruizinga, W.H.; Vaalburg, W.; Hummelen, J.C.

    1989-01-01

    13C2-17α-ethinylestradiol (13C2-EE2) was synthesized from estrone and 13C2-C2H2-gas to measure the metabolic clearance rate and the plasma concentration of 17α-ethinylestradiol (EE2) in tall girls, who are treated with high dosages of this estrogen. Interesting characteristics determined by (i) MS:

  9. 48 CFR 909.406-3 - Procedures.

    Science.gov (United States)

    2010-10-01

    ... in accordance with 10 CFR part 1010, Conduct of Employees, § 1010.217(b), Cooperation with the... of any mitigating factors, and arguments concerning the imposition, scope, or duration of a proposed... written findings of fact to the Debarring Official (together with a transcription of the proceeding,...

  10. 76 FR 62055 - Wabash Gas Storage, LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned...

    Science.gov (United States)

    2011-10-06

    ... Wabash Gas Storage, LLC (Wabash) near Paris in Edgar County, Illinois. This EA will be used by the..., 2011, Knights of Columbus Meeting Hall, 614 North Main Street, Paris, IL 61944, (217) 465-1085. This... mutually acceptable agreement. However, if the project is approved by the Commission, that approval...

  11. Comparison of chloroquine with artesunate in the treatment of cerebral malaria in Ghanaian children

    DEFF Research Database (Denmark)

    Goka, B Q; Adabayeri, V; Ofori-Adjei, E;

    2001-01-01

    and neurological deficits were documented. There was no difference in mortality rates (chloroquine, 16.7 per cent; artesunate, 21.7 per cent; p = 0.6), neurological deficit at day 14 (chloroquine, 0 per cent; artesunate, 4.3 per cent; p = 0.3), resolution of fever (p = 0.55), and coma recovery time (p = 0...

  12. Atorvastatin affects low density lipoprotein and non-high density lipoprotein cholesterol relations with apolipoprotein B in type 2 diabetes mellitus: modification by triglycerides and cholesteryl ester transfer protein

    NARCIS (Netherlands)

    P.J.W.H. Kappelle; L. Zwang; M.V. Huisman; J.D. Banga; W.J. Sluiter; G.M. Dallinga-Thie; R.P.F. Dullaart

    2009-01-01

    Objectives: Non-HDL-cholesterol (non-HDL-C) and apolipoprotein (apo) B are proposed as treatment targets. The extent to which statin therapy affects relationships of LDL-C and non-HDL-C with apoB was examined in type 2 diabetes. Methods: Analyses were performed in 217 hypertriglyceridaemic type 2 di

  13. Insects of terrestrial origin over Indian Ocean during north-east monsoon

    Digital Repository Service at National Institute of Oceanography (India)

    Pathak, S.C.; Kulshrestha, V.; Choubey, A.K.; Parulekar, A.H.

    ,217 airborne insects belonging to 7 orders, 53 families and 194 species were collected from 57 sampling stations, over 33 days. Hemiptera was the order with the highest number of insects (1,450), followed by Diptera (1,111), Hymenoptera (510) and Coleoptera...

  14. Planck 2013 results. VI. High Frequency Instrument data processing

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.;

    2013-01-01

    We describe the processing of the 531 billion raw data samples from the High Frequency Instrument (HFI), which we performed to produce six temperature maps from the first 473 days of Planck-HFI survey data. These maps provide an accurate rendition of the sky emission at 100, 143,217, 353, 545, an...

  15. Planck early results. VI. The High Frequency Instrument data processing

    DEFF Research Database (Denmark)

    Bucher, M.; Castex, G.; Colley, J.-M.;

    2011-01-01

    We describe the processing of the 336 billion raw data samples from the High Frequency Instrument (HFI) which we performed to produce six temperature maps from the first 295 days of Planck-HFI survey data. These maps provide an accurate rendition of the sky emission at 100, 143, 217, 353, 545 and...

  16. Planck 2013 results. XVII. Gravitational lensing by large-scale structure

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.;

    2013-01-01

    On the arcminute angular scales probed by Planck, the cosmic microwave background (CMB) anisotropies are gently perturbed by gravitational lensing. Here we present a detailed study of this eect, detecting lensing independently in the 100, 143, and 217 GHz frequency bands with an overall significa...

  17. Planck early results. IV. First assessment of the High Frequency Instrument in-flight performance

    DEFF Research Database (Denmark)

    Bréelle, E.; Bucher, M.; Cressiot, C.;

    2011-01-01

    The Planck High Frequency Instrument (HFI) is designed to measure the temperature and polarization anisotropies of the cosmic microwave background and Galactic foregrounds in six ~30% bands centered at 100, 143, 217, 353, 545, and 857 GHz at an angular resolution of 10′ (100 GHz), 7′ (143 GHz), a...

  18. Water Reclamation and Reuse.

    Science.gov (United States)

    Smith, Daniel W.

    1978-01-01

    Presents a literature review of water reclamation and reuse. This review covers: (1) water resources planning; (2) agriculture and irrigation; (3) ground recharge; (4) industrial reuse; (5) health considerations; and (6) technology developments. A list of 217 references is also presented. (HM)

  19. Sustainable Biomass Resources for Biogas Production

    DEFF Research Database (Denmark)

    Meyer, Ane Katharina Paarup

    and 640,000 GJ respectively. The energy return on energy investment when utilising roadside grass were estimated to range from 2.17 to 2.88, while 1.7 to 3.3 for the use of meadow grass. It was found that the concept of utilising grasses from nature habitats and roadside verges can function as a provider...

  20. Somatic copy number alterations associated with Japanese or endometriosis in ovarian clear cell adenocarcinoma.

    Directory of Open Access Journals (Sweden)

    Aikou Okamoto

    Full Text Available When compared with other epithelial ovarian cancers, the clinical characteristics of ovarian clear cell adenocarcinoma (CCC include 1 a higher incidence among Japanese, 2 an association with endometriosis, 3 poor prognosis in advanced stages, and 4 a higher incidence of thrombosis as a complication. We used high resolution comparative genomic hybridization (CGH to identify somatic copy number alterations (SCNAs associated with each of these clinical characteristics of CCC. The Human Genome CGH 244A Oligo Microarray was used to examine 144 samples obtained from 120 Japanese, 15 Korean, and nine German patients with CCC. The entire 8q chromosome (minimum corrected p-value: q = 0.0001 and chromosome 20q13.2 including the ZNF217 locus (q = 0.0078 were amplified significantly more in Japanese than in Korean or German samples. This copy number amplification of the ZNF217 gene was confirmed by quantitative real-time polymerase chain reaction (Q-PCR. ZNF217 RNA levels were also higher in Japanese tumor samples than in non-Japanese samples (P = 0.027. Moreover, endometriosis was associated with amplification of EGFR gene (q = 0.047, which was again confirmed by Q-PCR and correlated with EGFR RNA expression. However, no SCNAs were significantly associated with prognosis or thrombosis. These results indicated that there may be an association between CCC and ZNF217 amplification among Japanese patients as well as between endometriosis and EGFR gene amplifications.

  1. Single Electrode Heat Effects

    DEFF Research Database (Denmark)

    Jacobsen, Torben; Broers, G. H. J.

    1977-01-01

    Standard Peltier entropies for the reactions in molten carbonate paste electrolytes at 1000°K have been determined fromthermogalvanic measurements. The results are –217 and –118 J/mole°K,respectively. No dependence on electrolyte composition is observed. The reversiblepart of the Peltier entropy...

  2. Cross-Lagged Relationships between Career Aspirations and Goal Orientation in Early Adolescents

    Science.gov (United States)

    Creed, Peter; Tilbury, Clare; Buys, Nick; Crawford, Meegan

    2011-01-01

    We surveyed 217 students (145 girls; average age = 14.6 years) on two occasions, twelve months apart, on measures of career aspirations (job aspirations, job expectations, educational aspirations) and goal orientation (learning, performance-prove, performance-avoid), and tested the causal relationship between goal orientation and aspirations. We…

  3. Risk Factors Associated with Outcome in Liver Retransplantation : Multicentric Study

    NARCIS (Netherlands)

    Mattos, Rogerio O.; Linhares, Marcelo M.; Matos, Delcio; Adam, Rene; Bismuth, Henri; Castaing, Denis; Konietzko, Achim; Lerut, Jan; Porte, Robert J.; Neville, Jamieson; Azoulay, Daniel

    2015-01-01

    Background/Aims: To externally validate the predictive mathematical model of survival designed by Linhares et al. (2006). Methodology: This retrospective study was conducted on 217 individuals submitted to liver retransplantation from January 2000 to December 2008 in four European centers. The follo

  4. Predicting mobility outcome one year after stroke: a prospective cohort study.

    NARCIS (Netherlands)

    Port, I.G. van de; Kwakkel, G.; Schepers, V.P.; Lindeman, E.

    2006-01-01

    OBJECTIVE: To develop a prognostic model to predict mobility outcome one year post-stroke. DESIGN: Prospective cohort study in patients with a first-ever stroke admitted for inpatient rehabilitation. PATIENTS: A total of 217 patients with stroke (mean age 58 years) following inpatient rehabilitation

  5. Performance and Difficulties of Students in Formulating and Solving Quadratic Equations with One Unknown

    Science.gov (United States)

    Didis, Makbule Gozde; Erbas, Ayhan Kursat

    2015-01-01

    This study attempts to investigate the performance of tenth-grade students in solving quadratic equations with one unknown, using symbolic equation and word-problem representations. The participants were 217 tenth-grade students, from three different public high schools. Data was collected through an open-ended questionnaire comprising eight…

  6. EST Table: FS917517 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS917517 E_FL_fufe_41J10_F_0 10/09/28 61 %/218 aa ref|XP_001861467.1| pickel [Culex... quinquefasciatus] gb|EDS35652.1| pickel [Culex quinquefasciatus] 10/09/12 56 %/217 aa FBpp0229973|DvirGJ155

  7. Politikberatung aus den Staatswissenschaften = Riigiteadus poliitikanõustajana / Jürgen Backhaus

    Index Scriptorium Estoniae

    Backhaus, Jürgen

    2005-01-01

    Teadmistepõhine poliitika eeldab, et teadmised, millele poliitika peab tuginema, on tõepoolest ka olemas ja et on olemas keegi, kes oskab neid poliitikuile efektiivselt edastada. Sotsiaalteaduste puhul kerkib esile probleem, et vastav kommunikatsioon on üha puudulikum, leiab autor. Vt. ka kommentaare lk. 217-222,467-472

  8. Russki stihh : metrika, sistemõ stihhoslozhenija, prosodija (generativnõi podhod) / Mihhail Lotman

    Index Scriptorium Estoniae

    Lotman, Mihhail, 1952-

    2000-01-01

    Russian verse: its metrics, versification systems, and prosody (generative synopsis). Lk. 217-218 ; Vene värss: meetrika, värsisüsteemid ja prosoodika (generatiivne ülevaade). Lk. 241. Üldisest värsimõõduteooriast ja selle rakendamisest vene värsile

  9. Respiratory tract tumor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2010336 Study on the association between DNA double-strand break repair gene NBS1 polymorphisms and susceptibility on lung cancer. FAN Lihui(樊丽辉),et al. Dept Epidemiol,Public Health Sch,Fujian Med Univ,Fuzhou 350004.Chin J Epidemiol 2010;31(2):213-217.

  10. Cryptanalysis of the ESSENCE Family of Hash Functions

    DEFF Research Database (Denmark)

    Mouha, Nicky; Sekar, Gautham; Aumasson, Jean-Philippe;

    2010-01-01

    and the corresponding compression function, each requiring only 2^17 output bits. This observation is extended to key-recovery attacks on the block cipher. Next, we show that the omission of round constants allows slid pairs and fixed points to be found. These attacks are independent of the number of rounds. Finally...

  11. 50 CFR 697.2 - Definitions.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF COMMERCE (CONTINUED) ATLANTIC COASTAL FISHERIES COOPERATIVE MANAGEMENT General Provisions § 697... § 217.12 of this title. Atlantic Coastal Act means the Atlantic Coastal Fisheries Cooperative Management... fish harvested. Commission means the Atlantic States Marine Fisheries Commission established under...

  12. Implementing E-Learning Designed Courses in General Education

    Science.gov (United States)

    Nuangchalerm, Prasart; Sakkumduang, Krissada; Uhwha, Suleepornn; Chansirisira, Pacharawit

    2014-01-01

    The aim of this study is to implement e-learning designed course for general education. The study employed 3 phases for developing e-learning course: contextual study, designing, and implementing. Two courses general education, 217 undergraduate students are participated the study. Research tool consisted of interview about e-learning form and…

  13. Analysis of natural isolates of Lactobacilli resistant to bacteriocin nisin

    Directory of Open Access Journals (Sweden)

    Strahinić Ivana D.

    2005-01-01

    Full Text Available The collection of lactic acid bacteria (LAB was made by isolation of microorganisms from fermented products traditionally manufactured in different geographical regions (high mountains, river valleys, seaside, etc. Among collected LAB, 51 isolates were identified as Lactobacillus sp. Results showed that all isolated lactobacilli were mesophilic strains, since they grew at 15°C and 30°C but not at 45°C. Testing the ability of isolated lactobacilli to grow in the presence of nisin revealed that Lactobacillus sp. isolates designed BGCGK4, BGHN40, BGBUK2-8, BGBUK2-7 and BGBUK2-16 were resistant to nisin. Determination of the minimal inhibitory concentrations (MIC for nisin revealed that the most resistant isolate was Lactobacillus sp. BGCGK4. Isolate BGBUK2-16, determined as Lactobacillus paracasei subsp. paracasei, produces bacteriocin, named Bac217 and showed a resistance to 8000 IU/ml of nisin. Plasmid curing of BGBUK2-16 resulted in derivatives BGBUK2-16/K2 and BGBUK2-16/K4. Derivative BGBUK2-16/K2 retained resistance to Bac217 and nisin, but lost the ability to synthesise Bac217. Derivative BGBUK2-16/K4 lost concomitantly the resistance to both Bac217 and nisin.

  14. Crystallization of a flavodoxin involved in nitrogen fixation in Rhodobacter capsulatus

    OpenAIRE

    Pérez-Dorado, Inmaculada; Bortolotti, Ana; Cortez, Néstor; Hermoso, Juan A.

    2008-01-01

    The flavodoxin NifF from R. capsulatus, a candidate for nitrogenase reduction during nitrogen fixation, has been crystallized using the hanging-drop vapour-diffusion method. Preliminary X-ray data processing at 2.17 Å resolution allowed determination of the crystal system and unit-cell parameters.

  15. EST Table: FY002291 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FY002291 bmov7h16 11/11/04 99 %/217 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori]..._971398.1| PREDICTED: similar to vitellogenin [Tribolium castaneum] FS939370 bmov ...

  16. Sisters in the Struggle: African American Female Graduate Students Coping with Racism and Racism-Related

    Science.gov (United States)

    Foster, Kelsie

    2013-01-01

    This study examined if coping was predictive of perceived racism and racism related stress of African American female graduate students. Participants were 217 African American female graduate students attending Predominantly White Institutions (PWIs), Hispanic Serving Institutions (HSIs) and Historically Black Colleges and Universities (HBCUs) and…

  17. Hopelessness and Suicidal Behavior among Chinese, Thai and Korean College Students and Predictive Effects of the World Health Organization's WHOQOL-BREF

    Science.gov (United States)

    Kay, Noy; Li, Kaigang; Xiao, Xia; Nokkaew, Nattiporn; Park, Bock-Hee

    2009-01-01

    The purpose of this study was to assess the current status of suicide behavior and to examine the association between hopeless feelings, suicidal behavior and components of the WHO Quality-of-Life-BREF instrument among college students (n = 1,217) in China, Thailand, and Korea. Results showed 3.7% Thai, 10% Chinese, and 13.2% Korean students…

  18. Ozarenije, ili lesnitsa, vedushtshaja k ikone / Valentina Siig

    Index Scriptorium Estoniae

    Siig, Valentina

    2007-01-01

    Ikooninäitus "Õigeusklik ikoon Eestis" Vene kultuurikeskuse galeriis Tallinnas, eksponeeritud 18-20. sajandist 97 ikooni. Näituse külastatavusest. Ikoonimaalija Aleksandr Balajevi (1947) eluloost, maalitud ikoonidest. Ill. lk. 217 ja 219 kunstniku 7 ikooni

  19. Predictors of Changes in Body Image Concerns of Chinese Adolescents

    Science.gov (United States)

    Chen, Hong; Jackson, Todd

    2009-01-01

    This nine-month prospective study tested the extent to which risk factors implicated in recent accounts of body dissatisfaction predicted changes in body image concerns of adolescent boys and girls in China. A sample of 593 Chinese adolescents (217 boys, 376 girls) completed measures of weight esteem, appearance esteem and physical stature concern…

  20. 77 FR 38859 - Governors' Designees Receiving Advance Notification of Transportation of Certain Shipments of...

    Science.gov (United States)

    2012-06-29

    ... Nuclear Waste and Spent Fuel On January 6, 1982 (47 FR 596 and 47 FR 600), the U.S. Nuclear Regulatory...) 782-7860, Fax: (217) 558-7398. INDIANA Major Jeffrey L. SAME. Walker, Commander, Commercial Vehicle... 12226-2251, (518) 292-2301, 24 hours: (518) 292- 2200, Fax: (518) 322-4978. NORTH CAROLINA...

  1. Acute toxicity and histopathology of channel catfish fry exposed to peracetic acid

    Science.gov (United States)

    Channel catfish Ictalurus punctatus yolk-sac fry and swim-up fry were exposed to peracetic acid (PAA) for 48h in static toxicity bioassays at 23C. The test water was 217 and 126 mg/L (as CaCO3) total alkalinity and total hardness, respectively. Probit LC50 values were estimated with the trimmed Sp...

  2. 77 FR 2954 - Notice of Stakeholder Meetings on Rural Energy for America Program

    Science.gov (United States)

    2012-01-20

    ... A1, Boise, ID 83709, (208) 378-5623, Brian.Buch@id.usda.gov . Illinois Mary Warren, USDA Rural Development, 2118 West Park Court, Suite A, Champaign, IL 61821, (217) 403-6218, mary.warren@il.usda.gov... Rosa Road, Suite 238, Richmond, VA 23229, (434) 392-4906 Ext. 125, (804) 287-1606,...

  3. 78 FR 34975 - Notice of Contract Proposals (NOCP) for the Advanced Biofuels Payment Program

    Science.gov (United States)

    2013-06-11

    .... Barnes Drive, Suite A1, Boise, ID 83709, (208) 378-5623, brian.buch@id.usda.gov . Illinois Mary Warren, USDA Rural Development, 2118 West Park Court, Suite A, Champaign, IL 61821, (217) 403-6218, mary.warren... Rosa Road, Richmond, VA 23229, (804) 287-1594, laurette.tucker@va.usda.gov . Virgin Islands...

  4. 78 FR 19183 - Notice of Funding Availability for the Rural Energy for America Program

    Science.gov (United States)

    2013-03-29

    ....buch@id.usda.gov Illinois Mary Warren, USDA Rural Development, 2118 West Park Court, Suite A, Champaign, IL 61821, (217) 403-6218, mary.warren@il.usda.gov Indiana Jerry Hay, USDA Rural Development, 5975... Development, Culpeper Building, Suite 238, 1606 Santa Rosa Road, Richmond, VA 23229, (804) 287-1594,...

  5. Equational axioms of test algebra

    NARCIS (Netherlands)

    Hollenberg, M.

    2008-01-01

    We present a complete axiomatization of test algebra ([24,18,29]), the two-sorted algebraic variant of Propositional Dynamic Logic (PDL,[21,7]). The axiomatization consists of adding a finite number of equations to any axiomatization of Kleene algebra ([15,26,17,4]) and algebraic translations of the

  6. Problems of Implementation of Strategic Plans for Secondary Schools' Improvement in Anambra State

    Science.gov (United States)

    Chukwumah, Fides Okwukweka; Ezeugbor, Carol Obiageli

    2015-01-01

    This study investigated the extent of problems of strategic plans implementation for secondary schools' improvement in Anambra State, Nigeria for quality education provision. The study used a descriptive survey design paradigm. Respondents comprised 217 principals. There was no sampling. All the principals were used. Data were collected using…

  7. Developing Quality Strategic Plan in Secondary Schools for Successful School Improvement

    Science.gov (United States)

    Chukwumah, Fides Okwukweka

    2015-01-01

    The study examined the extent to which development of quality strategic plans for Anambra State secondary schools' improvement had been done by schools. The research design used was a descriptive survey. Respondents comprised 217 principals. There was no sampling since all the principals were used. Data were collected using "Schools'…

  8. Identifying the Challenging Factors in the Transition from Colleges of Engineering to Employment

    Science.gov (United States)

    Baytiyeh, Hoda; Naja, Mohamad

    2012-01-01

    The transition from university to a career in engineering is a challenging process. This study examined the perceptions of engineering graduates regarding the difficulties they encountered in their transition from the university to the workplace. Lebanese practising engineers (n=217), living around the world, were surveyed to identify their…

  9. The Physician Values in Practice Scale-Short Form: Development and Initial Validation

    Science.gov (United States)

    Rogers, Mary E.; Creed, Peter A.; Searle, Judy; Hartung, Paul J.

    2011-01-01

    The authors conducted two studies to develop and test a short form of the 60-item Physician Values in Practice Scale (PVIPS). The PVIPS, which draws on the theory of work adjustment for its theoretical base, measures personal values specific to medical occupations. In Study 1, 217 first- and final-year medical students completed a Web-based…

  10. EST Table: FS917079 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS917079 E_FL_fufe_40D23_F_0 10/09/28 99 %/217 aa ref|NP_001040402.1| preimplantation... protein [Bombyx mori] gb|ABF51322.1| preimplantation protein [Bombyx mori] 10/09/12 81 %/213 aa FBpp02346

  11. Atorvastatin affects low density lipoprotein and non-high density lipoprotein cholesterol relations with apolipoprotein B in type 2 diabetes mellitus : modification by triglycerides and cholesteryl ester transfer protein

    NARCIS (Netherlands)

    Kappelle, Paul J. W. H.; Zwang, Louwerens; Huisman, Menno V.; Banga, Jan Dirk; Sluiter, Wim. J.; Dallinga-Thie, Geesje M.; Dullaart, Robin P. F.

    2009-01-01

    Objectives: Non-HDL-cholesterol (non-HDL-C) and apolipoprotein (apo) B are proposed as treatment targets. The extent to which statin therapy affects relationships of LDL-C and non-HDL-C with apoB was examined in type 2 diabetes. Methods: Analyses were performed in 217 hypertriglyceridaemic type 2 di

  12. Correlates of Early Alcohol and Drug Use in Hispanic Adolescents: Examining the Role of ADHD with Comorbid Conduct Disorder, Family, School, and Peers

    Science.gov (United States)

    Lopez, Barbara; Schwartz, Seth J.; Prado, Guillermo; Huang, Shi; Rothe, Eugenio M.; Wang, Wei; Pantin, Hilda

    2008-01-01

    This study examined correlates of early adolescent alcohol and drug use in a community sample of 217 eighth-grade adolescents with behavior problems and from Hispanic/Latino immigrant families. Structural equation modeling was used to examine relationships of multiple contexts (e.g., family, school, and peers) to alcohol and drug use. Results…

  13. 75 FR 47701 - Electronic System for Travel Authorization (ESTA): Travel Promotion Fee and Fee for Use of the...

    Science.gov (United States)

    2010-08-09

    ... for the use of ESTA as set by the Secretary of Homeland Security to ensure recovery of the full costs... and also establish a $10 travel promotion fee. The benefits of ESTA include enhanced security, cost... SECURITY U.S. Customs and Border Protection 8 CFR Part 217 RIN 1651-AA83 Electronic System for...

  14. Value of endometrial thickness measurement for diagnosing focal intrauterine pathology in women without abnormal uterine bleeding

    DEFF Research Database (Denmark)

    Dreisler, E; Sorensen, S Stampe; Ibsen, P H;

    2009-01-01

    modulators (n = 2). Thus, 375 women without AUB were included (217 pre- and 158 postmenopausal). Receiver-operating characteristics (ROC) curves for endometrial thickness and focal lesion were analyzed. RESULTS: Focal intrauterine pathology was confirmed in 41 women (35 with polyps, five with submucosal...

  15. AcEST: DK946499 [AcEST

    Lifescience Database Archive (English)

    Full Text Available +ELESHA Q+L EVYP+GP+ Sbjct: 187 ILVNTFIELESHAIQSLSGSTVPEVYPVGPI 217 >tr|Q8W237|Q8W237_DORBE Betanidin 6-O-glucosyltransferase OS=Doro...theanthus bellidiformis PE=2 SV=1 Length = 481 Score = 33.1 bits (74), Expect = 7.1

  16. 2009年第2期问题解答

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ 217.已知在△ABC中,D为BC的中点,AE为过A的任一条射线,且BM⊥AE,CN⊥AE,M,N为垂足,求证:∠DMN=∠DNM. 证明:分别延长MD、CN,交于点F,因为BM⊥AE,CN⊥AE,则BM//CN,所以∠BMD=∠CFD.

  17. A Germline Variant in the PANX1 Gene Has Reduced Channel Function and Is Associated with Multisystem Dysfunction.

    Science.gov (United States)

    Shao, Qing; Lindstrom, Kristin; Shi, Ruoyang; Kelly, John; Schroeder, Audrey; Juusola, Jane; Levine, Kara L; Esseltine, Jessica L; Penuela, Silvia; Jackson, Michael F; Laird, Dale W

    2016-06-10

    Pannexin1 (PANX1) is probably best understood as an ATP release channel involved in paracrine signaling. Given its ubiquitous expression, PANX1 pathogenic variants would be expected to lead to disorders involving multiple organ systems. Using whole exome sequencing, we discovered the first patient with a homozygous PANX1 variant (c.650G→A) resulting in an arginine to histidine substitution at position 217 (p.Arg217His). The 17-year-old female has intellectual disability, sensorineural hearing loss requiring bilateral cochlear implants, skeletal defects, including kyphoscoliosis, and primary ovarian failure. Her consanguineous parents are each heterozygous for this variant but are not affected by the multiorgan syndromes noted in the proband. Expression of the p.Arg217His mutant in HeLa, N2A, HEK293T, and Ad293 cells revealed normal PANX1 glycosylation and cell surface trafficking. Dye uptake, ATP release, and electrophysiological measurements revealed p.Arg217His to be a loss-of-function variant. Co-expression of the mutant with wild-type PANX1 suggested the mutant was not dominant-negative to PANX1 channel function. Collectively, we demonstrate a PANX1 missense change associated with human disease in the first report of a "PANX1-related disorder." PMID:27129271

  18. Challenges to Early Childhood Education in Rural China: Lessons from the Hebei Province

    Science.gov (United States)

    Hu, Bi Ying; Roberts, Sherron Killingsworth; Leng Ieong, Sylvia Sao; Guo, Haiying

    2016-01-01

    This research study examined the challenges faced by early childhood education (ECE) in rural China based on a qualitative study of 217 kindergarten classrooms in a large agricultural, rural province. This study utilised onsite teacher surveys, interviews, and observational field notes. This investigation's findings revealed important information…

  19. Education for a New World, 1994.

    Science.gov (United States)

    Institute of International Education, New York, NY.

    This annual report marks the 75th anniversary of the Institute of International Education (IIE) and describes the IIE's 1994 activities and programs. During 1994 more than 10,000 individuals studied, conducted research, received practical training, or provided international technical assistance under 248 programs IIE administered for 217 sponsors,…

  20. The High School Students' Perceptions and Attitudes toward Bioenergy

    Science.gov (United States)

    Özbas, Serap

    2016-01-01

    This research, which was tried with 217 high school students, was carried out to determine the perceptions and attitudes related to the usage of bioenergy. The research results showed that the students had the perception that there would be lack of food due to global warming, but bioenergy would prevent the world from global warming. Moreover,…

  1. AcEST: BP916758 [AcEST

    Lifescience Database Archive (English)

    Full Text Available tenolidase homolog OS=Xenopus laevis GN=cmbl PE=2 SV=1 Length = 246 Score = 47.4 bits (111), Expect = 2e-05 ...EQVSTLTQKLKEHCIV--NYQVKTFSGQTHGFVHR 217 >sp|Q6P7K0|CMBL_XENTR Carboxymethylenebutenolidase homolog OS=Xenopus tropicalis GN=cmb

  2. Data of evolutionary structure change: 1GCVC-1CBMC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GCVC-1CBMC 1GCV 1CBM C C -AFTACEKQTIGKIAQVLAKSPEAYGAECLARLFVTHPG... CA 220 ALA CA 206 LYS CA 238 1CBM... C 1CBMC FGDLSTPDAVMGNPK ASP CA 217 1CBM C 1CBM...2.8415520191192627 2 1CBM

  3. Keeping It Frat: Exploring the Interaction among Fraternity Membership, Disinhibition, and Hypermasculinity on Sexually Aggressive Attitudes in College-Aged Males

    Science.gov (United States)

    Corprew, Charles S., III.; Mitchell, Avery D.

    2014-01-01

    This study examines correlates that contribute to sexually aggressive attitudes toward women. Using a sample that includes 217 college males from 3 southern universities, the study evaluates the relationship between college men's hypermasculine and sexually aggressive attitudes, as well as how fraternity membership and disinhibition moderate…

  4. Textile Recycling, Convenience, and the Older Adult.

    Science.gov (United States)

    Domina, Tanya; Koch, Kathryn

    2001-01-01

    Results of a study to examine the recycling practices and needs of older adults (n=217) indicated that older adults do recycle traditional materials, but need accommodations for physical limitations. They report textile recycling as time consuming and difficult and used donations to religious organizations as their principal means of textile…

  5. 76 FR 24024 - Request for Information Relating to Studies Regarding the Resolution of Financial Companies Under...

    Science.gov (United States)

    2011-04-29

    ... information. SUMMARY: Section 216 of the Dodd-Frank Wall Street Reform and Consumer Protection Act (the ``Dodd... regarding international coordination relating to the resolution of systemic financial companies under the Bankruptcy Code and applicable foreign law. Section 216 and Section 217 of the Dodd-Frank Act each...

  6. Differential Effects of Support Providers on Adolescents' Mental Health.

    Science.gov (United States)

    Colarossi, Lisa G.; Eccles, Jacquelynne S.

    2003-01-01

    Examines the differential effects of parent, teacher, and peer social support on depression and self-esteem of 217 adolescents. Results indicate that female adolescents perceived significantly more support from friends than male adolescents did, whereas male adolescents perceived significantly more support from fathers. Self-esteem was…

  7. Factors Related to Sustained Implementation of Schoolwide Positive Behavior Support

    Science.gov (United States)

    McIntosh, Kent; Mercer, Sterett H.; Hume, Amanda E.; Frank, Jennifer L.; Turri, Mary G.; Mathews, Susanna

    2013-01-01

    The purpose of this study was to identify factors associated with sustainability of school-based interventions and the relative contributions of those factors to predicting sustained implementation of Schoolwide Positive Behavior Support (SWPBS). Participants were respondents from 217 schools across 14 U.S. states. Sustainability factors were…

  8. The Effects of Gender and Loneliness Levels on Ways of Coping among University Students

    Science.gov (United States)

    Cecen, A. Rezan

    2008-01-01

    The purpose of this study is to determine the effects of gender differences and levels of loneliness on ways of coping. The sample of the study is composed of 462 university students (245 male, 217 female) from different departments from the Education Faculty at Cukurova University. In this study to collect data related to loneliness as an…

  9. 40 CFR 80.540 - How may a refiner be approved to produce gasoline under the GPA gasoline sulfur standards in 2007...

    Science.gov (United States)

    2010-07-01

    ... produce gasoline under the GPA gasoline sulfur standards in 2007 and 2008? 80.540 Section 80.540... under the GPA gasoline sulfur standards in 2007 and 2008? (a) A refiner that has been approved by EPA under § 80.217 for the geographic phase-in area (GPA) gasoline sulfur content standards under §...

  10. 78 FR 78952 - Access by EPA Contractors to Information Claimed as Confidential Business Information (CBI...

    Science.gov (United States)

    2013-12-27

    ... Register Notice (77 FR 217, November 8, 2012, pp. 66977-66978), require access to CBI submitted to us under the Clean Air Act and in connection with the Mandatory Greenhouse Gas (GHG) Reporting Rule [40 CFR... the fuels used to operate them, and by encouraging travel choices that minimize emissions. In order...

  11. 12.4.Colon,rectum and anus

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920116 A study on chromosome instabiltyin patients with large bowel carcinoma andlarge bowel adenoma.Li Minglie (李明烈),etal.Shanghai Cancer Instit.Tumor 1991; 11 (5):215-217.The chromosome instability of peripheral lym-phocytes was studied in 10 patients with largebowel carcinoma (LBC),10 patients with large

  12. Vaccine Risk/Benefit Communication: Effect of an Educational Package for Public Health Nurses

    Science.gov (United States)

    Davis, Terry C.; Fredrickson, Doren D.; Kennen, Estela M.; Humiston, Sharon G.; Arnold, Connie L.; Quinlin, Mackey S.; Bocchini, Joseph A., Jr.

    2006-01-01

    The purpose of this study was to determine whether an in-service for public health nurses (PHNs) and accompanying educational materials could improve vaccine risk/benefit communication. The content and timing of vaccine communication were recorded during 246 pre-and 217 post-intervention visits in two public health immunization clinics.…

  13. 75 FR 41405 - Energy Priorities and Allocations System Regulations

    Science.gov (United States)

    2010-07-16

    ... infrastructure means any systems and assets, whether physical or cyber-based, so vital to the United States that... Part 217 RIN 1901-AB28 Energy Priorities and Allocations System Regulations AGENCY: Department of..., DOE Energy Priorities and Allocations System (EPAS) regulations. 10 CFR part 216 implements...

  14. 50 CFR 14.22 - Certain antique articles.

    Science.gov (United States)

    2010-10-01

    ....22 Certain antique articles. Any person may import at any Customs Service port designated for such purpose, any article (other than scrimshaw, defined in 16 U.S.C 1539(f)(1)(B) and 50 CFR 217.12 as any art... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Certain antique articles. 14.22 Section...

  15. Prothrombotic coagulation defects and cardiovascular risk factors in young women with acute myocardial infarction

    NARCIS (Netherlands)

    Tanis, BC; Bloemenkamp, DGM; van den Bosch, MAAJ; Kemmeren, JM; Algra, A; van de Graaf, Y; Rosendaal, FR

    2003-01-01

    We investigated the effect of prothrombotic coagulation defects in combination with smoking and other conventional risk factors on the risk of myocardial infarction in young women. In 217 women with a first myocardial infarction before the age of 50 years and 763 healthy control women from a populat

  16. Data of evolutionary structure change: 1ACPA-2DEGF [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ACPA-2DEGF 1ACP 2DEG A F STIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDT...HH EEE EEEEEEE EEEEEEEEEE -------- 0 1ACP... A 1ACPA EEFDT-----EIP...ine> ARG CA 217 LYS CA 149 THR CA 172 1ACP... A 1ACPA ELVMALEEEFDT

  17. Enhancing Student Motivation: Extensions from Job Enrichment Theory and Practice.

    Science.gov (United States)

    Bloom, Arvid J.; Yorges, Stefani L.; Ruhl, Angela J.

    2000-01-01

    Explores classroom extensions of job enrichment theory by administering a modified Job Diagnostic Survey, a widely employed organizational research tool that assesses each core job characteristic, to 217 psychology students along with outcome scales assessing their course motivation, satisfaction, performance, absenteeism, interest, and desire to…

  18. 77 FR 37408 - Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2012-06-21

    ... Protections (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human...; email address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a... as sign language interpretation or other reasonable accommodations, should notify the...

  19. 76 FR 58006 - Meeting of the Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2011-09-19

    ... Protections (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human...-mail address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a... who plan to attend the meeting and need special assistance, such as sign language interpretation...

  20. 76 FR 37354 - Meeting of the Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2011-06-27

    ... Protections (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human...-mail address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a... sign language interpretation or other reasonable accommodations, should notify the designated...

  1. 77 FR 58383 - Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2012-09-20

    ... Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human Services, 1101...: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a, Section 222 of.... Individuals who plan to attend the meeting and need special assistance, such as sign language...

  2. 78 FR 36783 - Meeting of the Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2013-06-19

    ... (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human Services... address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a, Section.... Individuals who plan to attend the meeting and need special assistance, such as sign language...

  3. 75 FR 59264 - Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2010-09-27

    ... (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human Services... address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a, Section.... Individuals who plan to attend the meeting and need special assistance, such as sign language...

  4. 78 FR 12061 - Meeting of the Secretary's Advisory Committee on Human Research Protections

    Science.gov (United States)

    2013-02-21

    ... Protections (OHRP), or Julia Gorey, J.D., Executive Director, SACHRP; U.S. Department of Health and Human...; email address: Julia.Gorey@hhs.gov . SUPPLEMENTARY INFORMATION: Under the authority of 42 U.S.C. 217a.... Individuals who plan to attend the meeting and need special assistance, such as sign language...

  5. 75 FR 6239 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Science.gov (United States)

    2010-02-08

    .... 57579 (March 28, 2008), 73 FR 18587 (April 4, 2008)(SR-NASDAQ-2008-026)(notice of filing and immediate... Exchange Act Release No. 60874 (October 23, 2009), 74 FR 56682 (November 2, 2009)(SR-NASDAQ-2009-091.... Inc 117 AMR AMR Corp 217 MET MetLife Inc. 166 ANF Abercrombie & 187 MMM 3M Co. Fitch Co 172...

  6. VizieR Online Data Catalog: Transiting planets search Matlab/Octave source code (Ofir+, 2014)

    Science.gov (United States)

    Ofir, A.

    2014-01-01

    The Matlab/Octave source code for Optimal BLS is made available here. Detailed descriptions of all inputs and outputs are given by comment lines in the file. Note: Octave does not currently support parallel for loops ("parfor"). Octave users therefore need to change the "parfor" command (line 217 of OptimalBLS.m) to "for". (7 data files).

  7. 7 CFR 1280.223 - Reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Reports. 1280.223 Section 1280.223 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS....217, each first handler marketing lamb products of that person's own production, and each exporter...

  8. 78 FR 5439 - Environmental Impacts Statements; Notice of Availability

    Science.gov (United States)

    2013-01-25

    ... EIS No. 20130009, Final EIS, NPS, HI, Hawaii Volcanoes National Park Project, Protecting and Restoring..., Contact: J. Michael Bowen 217-492-4600. EIS No. 20130015, Draft Supplement, FHWA, CA, Mid County Parkway.../23/2009, Contact: Larry Blevin 916-978-6037. Revision to FR Notice Published 10/ 09/2009; The...

  9. Analysis of the weight loss of the testicles of mice after 14 and 400 MeV neutron irradiation

    CERN Document Server

    Laurent, J M

    1974-01-01

    The weight loss of the testicles was examined 28 days after neutron irradiation. A mathematical model was developed for evaluating cellular survival curves. The relative biological efficiency, determined using the value of D/sub 0/ calculated from the survival curves obtained, is 2.17 for 400 MeV neutron beams and 2.58 for 14 MeV neutron beams.

  10. Effect of stocking large channel catfish in a biofloc technology production system on production and incidence of common microbial off-flavor compounds

    Science.gov (United States)

    Density-dependent production and incidence of common microbial off-flavors caused by geosmin and 2-methylisoborneol were investigated in an outdoor biofloc technology production system stocked with stocker-size (217 g/fish) channel catfish at 1.4, 2.1, or 2.8 kg/m3. Individual weight at harvest rang...

  11. Cold rotation in the reaction 19F+15V

    Institute of Scientific and Technical Information of China (English)

    WangQi; LuJun; 等

    1997-01-01

    Excitation functions of the dissipative products in the reaction 19F+51V have been measured from 102.25to 109.50MeV in a step of 250keV at θ=21.7°,Nuclear temperature of the system is extracted and discussed by using a concept of cold rotation.

  12. Production and identification of new, neutron-rich nuclei in the $^{208}$Pb region

    CERN Document Server

    Rykaczewski, K; Plochocki, A; Karny, M; Szerypo, J; Evensen, A H; Kugler, E; Lettry, Jacques; Ravn, H L; Van Duppen, P; Andreyev, A; Huyse, M; Wöhr, A; Jokinen, A; Äystö, J; Nieminen, A; Huhta, M; Ramdhane, M; Walter, G; Hoff, P

    2000-01-01

    The recently developed methods allowing the experimental studies on new neutron-rich nuclei beyond doubly-magic $^{208}$Pb are briefly described. An identification of new neutron-rich isotopes $^{215}$Pb and $^{217}$Bi, and new decay properties of $^{216}$Bi studied by means of a pulsed release element selective technique at PS Booster- ISOLDE are reported. (9 refs).

  13. Living Together: The Impact of the Intifada and the Peace Negotiations on Attitudes toward Coexistence of Arab and Jewish Pupils in Ethnically Segregated and Mixed Schools in Jaffa.

    Science.gov (United States)

    Zuzovsky, Ruth

    1997-01-01

    Changes in the willingness of Jews and Arabs to coexist were studied in 1989 with 217 12-year-olds and in 1994 with 194 in Jaffa (Israel), where both Jews and Arabs live. Separatist attitudes increased and faith in coexistence decreased, but mixed schools seemed to improve attitudes toward coexistence. (SLD)

  14. A prospective study on parental coping 4 months after termination of pregnancy for fetal anomalies

    NARCIS (Netherlands)

    Korenromp, M. J.; Page-Christiaens, G. C. M. L.; van den Bout, J.; Mulder, E. J. H.; Hunfeld, J. A. M.; Potters, C. M. A. A.; Erwich, J. J. H. M.; van Binsbergen, C. J. M.; Brons, J. T. J.; Omtzigt, A. W. J.; Visser, G. H. A.; Beekhuis, J.R.

    2007-01-01

    Objective To identify short-term factors influencing psychological outcome of termination of pregnancy for fetal anomaly, in order to define those patients most vulnerable to psychopathology. Study Design A prospective cohort of 217 women and 169 men completed standardized questionnaires 4 months af

  15. 40 CFR Appendix A to Part 7 - Types of EPA Assistance as Listed in the “Catalog of Federal Domestic Assistance”

    Science.gov (United States)

    2010-07-01

    ... under the Resource Conservation and Recovery Act of 1976; as amended by the Solid Waste Disposal Act...) 13. Assistance provided by the Office of Research and Development under the Solid Waste Disposal Act... 1977, as amended; Pub. L. 95-217; 33 U.S.C. 1251 et seq.; Solid Waste Disposal Act, as amended by...

  16. Academic Achievements and Study Habits of College Students of District Pulwama

    Science.gov (United States)

    Bhat, Younis Illahi; Khandai, Hemant

    2016-01-01

    This study was undertaken to study the academic achievement and study habits of male and female college students of district Pulwama (J and k). The sample for the study was 410 including 193 male and 217 female college students .which was further divided into different groups of rural-urban dichotomy. For this purpose descriptive survey method was…

  17. Data of evolutionary structure change: 1MQVA-1CPRA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1MQVA-1CPRA 1MQV 1CPR A A --ATDVIAQRKAILKQMGEATKPIAAMLKGEAKWDQAVV...tryChain> 1CPR A 1CPRA KILATDVAPL...A 268 ALA CA 346 1CPR A 1CPRA...> SER CA 217 1CPR A 1CPRA...VID> 3 1CPR A 1CPRA

  18. Planck early results. XVIII. The power spectrum of cosmic infrared background anisotropies

    DEFF Research Database (Denmark)

    Bucher, M.; Delabrouille, J.; Giraud-Héraud, Y.;

    2011-01-01

    and the CIB mean, with ΔI / I = 15% from 217 to 857 GHz. In terms of clustering properties, the Planck data alone rule out the linear scale- and redshift-independent bias model. Non-linear corrections are significant. Consequently, we develop an alternative model that couples a dusty galaxy, parametric...

  19. Crossing the Line: Examination of Student Demographic Changes Concomitant with Declining Academic Performance in Elementary Schools

    Science.gov (United States)

    Hochbein, Craig; Duke, Daniel

    2011-01-01

    The purpose of this study is to examine the relationship between school decline and changes in school demographics. Using a population of 981 (N = 981) elementary schools, the authors identified samples of declining schools: Relational Decline (n = 510), Absolute Decline (n = 217), and Crossing the Line (n = 165). Latent growth models assessed…

  20. Certified reference material for radionuclides in fish flesh sample IAEA-414 (mixed fish from the Irish Sea and North Sea)

    DEFF Research Database (Denmark)

    Pham, M.K.; Sanchez-Cabeza, J.A.; Povinec, P.P.;

    2006-01-01

    certified for this material. Information on massic activities with 95% confidence intervals is given for six other radionuclides (Sr-90, Pb-210(Po-210), Ra-226, Pu-239, Pu-240 Pu-241). Less frequently reported radionuclides (Tc-99, I-129, Th-228, Th-230 and Np-217) and information on some activity and mass...

  1. Birth Order and Maladaptive Behavior in School-Aged Children.

    Science.gov (United States)

    Carmichael, Karla D.

    Drawing on Alfred Adler's theories on the effect of birth order on maladaptive behavior in children, this study focused on the relationship between birth order and the referral to counseling of school-aged children with maladaptive disorder. School-aged children (N=217) with academic or behavioral problems, ages 5 to 18, were referred to the staff…

  2. Evaluation of Five Microcomputer CAD Packages.

    Science.gov (United States)

    Leach, James A.

    1987-01-01

    Discusses the similarities, differences, advanced features, applications and number of users of five microcomputer computer-aided design (CAD) packages. Included are: "AutoCAD (V.2.17)"; "CADKEY (V.2.0)"; "CADVANCE (V.1.0)"; "Super MicroCAD"; and "VersaCAD Advanced (V.4.00)." Describes the evaluation of the packages and makes recommendations for…

  3. 7 CFR 2003.6 - Office of the Under Secretary.

    Science.gov (United States)

    2010-01-01

    ... internal controls. The office provides direct oversight to the Headquarters Budget Division, Financial... financial management matters and financial execution of the budget for the Rural Development agencies. This... Office of the Under Secretary. In accordance with 7 CFR § 2.17 the Secretary has delegated to the...

  4. Resolution of the Diagnosis among Parents of Children with Autism Spectrum Disorder: Associations with Child and Parent Characteristics

    Science.gov (United States)

    Milshtein, Shahaf; Yirmiya, Nurit; Oppenheim, David; Koren-Karie, Nina; Levi, Shlomit

    2010-01-01

    Resolution with the diagnosis of one's child involves coming to terms with and accepting the diagnosis and its implications. Parental resolution with the diagnosis was examined among 61 mothers and 60 fathers of 61 children with autism spectrum disorders aged 2-17 years. We investigated resolution rates and subtypes, and associations between…

  5. Herbal medicine use among Turkish patients with chronic diseases

    Directory of Open Access Journals (Sweden)

    Munevver Tulunay

    2015-09-01

    Conclusions: In this study herbal medicine use was found to be higher among patients who had been diagnosed with chronic diseases. Therefore physicians should be aware of herbal medicine usage of their patients and inform them about the effectivity and side effects of herbal medicines. [J Intercult Ethnopharmacol 2015; 4(3.000: 217-220

  6. Gclust Server: 31971 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 31971 PPT_174088 Cluster Sequences Related Sequences(20) 217 estExt_gwp_gw1.C_30325...; no annotation 3 1.00e-60 42.86 0.0 0.0 0.0 0.0 0.0 Show 31971 Cluster ID 31971 Sequence ID PPT_174088 Link

  7. Gclust Server: 197168 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 197168 Neq_NEQ545 Cluster Sequences - 217 hypothetical protein 1 1.00e-99 0.0 0.0 0.0 0.0 3.23 0.0 Show 1971...68 Cluster ID 197168 Sequence ID Neq_NEQ545 Link to cluster sequences Cluster Seque

  8. Comparison of Qinzhou bay wetland landscape information extraction by three methods

    Directory of Open Access Journals (Sweden)

    X. Chang

    2014-04-01

    and OO is 219 km2, 193.70 km2, 217.40 km2 respectively. The result indicates that SC is in the f irst place, followed by OO approach, and the third DT method when used to extract Qingzhou Bay coastal wetland.

  9. Data of evolutionary structure change: 1JDZC-2IQ5B [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available > 2IQ5B VRLDG-ASLHF >EEE - ...SYNQGGLFYQY e>E HHHHHHture> 2IQ5B QTESH----AVKIV > HH----HHHHH...ain>1JDZC EELEKSVMDGAKAV re...> HHHHHHHHHHHH> ATOM 5061 CA GLU C 217 95.716 121.480 11.777 1.

  10. PET/MR imaging of head/neck in the presence of dental implants: reducing image artifacts and increasing accuracy through inpainting

    DEFF Research Database (Denmark)

    Ladefoged, Claes; Beyer, Thomas; Keller, Sune;

    in the inpainted region, tongue and cerebellum. Furthermore, PET ratio images are computed for visual inspection. Results: The mean volume of implant-induced signal voids was (232±68) mL (min: 152mL, max: 348mL). The relative difference in mean SUV following inpainting as part of MR-AC (PET(/MR)Soft) was (217...

  11. Русский стих : метрика системы стихосложения, просодия (генеративный подход) / Михаил Лотман

    Index Scriptorium Estoniae

    Лотман, Михаил, 1952-

    2000-01-01

    Russian verse: its metrics, versification systems, and prosody (generative synopsis). Lk. 217-218 ; Vene värss: meetrika, värsisüsteemid ja prosoodika (generatiivne ülevaade). Lk. 241. Üldisest värsimõõduteooriast ja selle rakendamisest vene värsile

  12. Domain Modeling: NP_001561.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001561.3 chr3 Structural Basis for the Interaction of TAK1 Kinase with its Activ...ating Protein TAB1 p2evaa_ chr3/NP_001561.3/NP_001561.3_holo_194-543.pdb psi-blast 216I,217S,218Q,219G,224V,

  13. Domain Modeling: NP_071911.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_071911.3 chr10 Solution structure of the tandem four zf-C2H2 domain repeats of m...urine GLI-Kruppel family member HKR3 c2dlqa_ chr10/NP_071911.3/NP_071911.3_holo_111-217.pdb psi-blast 112C,1

  14. Using Relationships to Heal Trauma: Reflective Practices Creates a Therapeutic Preschool

    Science.gov (United States)

    Brinamen, Charles; Page, Farris

    2012-01-01

    More than 20 percent of children (ages 2-17) in the United States have witnessed and/or been victims of multiple forms of violence. Children from birth through age 5 are more likely to experience maltreatment and neglect than other age groups. Violence and trauma (including neglect), whether in the home or the community, have lasting effects on…

  15. Mathematics Achievement as a Function of within- and between-School Differences

    Science.gov (United States)

    Mohammadpour, Ebrahim; Abdul Ghafar, Mohamed Najib

    2014-01-01

    Achievement in mathematics of eighth-grade students is modeled as a function of within-school, between-school and cross-country differences. The data were obtained from 217,728 students, within 7,216 secondary schools, in 48 countries, who participated in the 2007 Trends in International Mathematics and Science Study. Multilevel analysis showed…

  16. 78 FR 36098 - Final Flood Elevation Determinations

    Science.gov (United States)

    2013-06-17

    ... 510 North Broadway, 4th Floor, Billings, MT 59101. Unincorporated Areas of Yellowstone County Maps are available for inspection at 217 North 27th Street, Billings, MT 59101. (Catalog of Federal Domestic... 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive Order...

  17. 77 FR 41781 - City of Quincy; FFP Project 109, LLC; Notice of Competing Preliminary Permit Applications...

    Science.gov (United States)

    2012-07-16

    ... Energy Regulatory Commission City of Quincy; FFP Project 109, LLC; Notice of Competing Preliminary Permit... May 1, 2012, City of Quincy and FFP Project 109, LLC filed preliminary permit applications pursuant to...: Mr. Charles Bevelheimer, 730 Maine Street, Quincy, IL 62301; (217) 228-4500. FFP Project 109,...

  18. 77 FR 41782 - City of Quincy; FFP Project 110, LLC; Notice of Competing Preliminary Permit Applications...

    Science.gov (United States)

    2012-07-16

    ... Energy Regulatory Commission City of Quincy; FFP Project 110, LLC; Notice of Competing Preliminary Permit... May 1, 2012, City of Quincy and FFP Project 110, LLC filed preliminary permit applications pursuant to... 62301; (217) 228-4500. FFP Project 110, LLC's proposed project would consist of: (1) Fourteen new...

  19. Endemism

    NARCIS (Netherlands)

    Vidal, J.E.

    1969-01-01

    In the Flore générale de l’Indochine, 217 families have been described, 1794 genera, c. 9000 species. There is an amount of endemism, on the basis of which attempts have been made towards an inner subdivision of the region. The problem is, that the endemism is of uncertain status. A few percentages

  20. Extending Campus Life to the Internet: Social Media, Discrimination, and Perceptions of Racial Climate

    Science.gov (United States)

    Tynes, Brendesha M.; Rose, Chad A.; Markoe, Suzanne L.

    2013-01-01

    Despite the fact that more college student interaction now takes place online, researchers have yet to examine the role the Internet plays in perceptions of campus racial climate. Using an online survey of a sample of 217 African American and European American college students, this study explored online factors including intergroup interaction as…

  1. Reference: AT1BOX [PLACE

    Lifescience Database Archive (English)

    Full Text Available AT1BOX Ueda T, Pichersky E, Malik VS, Cashmore AR The level of expression of the to...mato rbcs-3A gene is modulated by a far-upstream promoter element in a developmentary regulated manner. Plant Cell 1:217-227 (1989) PubMed: 2535544; GenBank: S44160; ...

  2. Promoting Teachers' Generalization of Intervention Use through Goal Setting and Performance Feedback

    Science.gov (United States)

    Duncan, Neelima G.; Dufrene, Brad A.; Sterling, Heather E.; Tingstrom, Daniel H.

    2013-01-01

    Consultation is beneficial for increasing teachers' intervention use for target students. However, little is known about teachers' generalized intervention use. This study is a systematic replication of Riley-Tillman and Eckert ("J Educ Psychol Consult" 12:217-241, 2001) and Martens et al. ("Sch Psychol Q" 12:33-41,…

  3. Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

    NARCIS (Netherlands)

    E. Melum; A. Franke; C. Schramm; T.J. Weismüller; D.N. Gotthardt; F.A. Offner; B.D. Juran; J.K. Laerdahl; V. Labi; E. Björnsson; R.K. Weersma; L. Henckaerts; A. Teufel; C. Rust; E. Ellinghaus; T. Balschun; K.M. Boberg; D. Ellinghaus; A. Bergquist; P. Sauer; E. Ryu; J.R. Hov; J. Wedemeyer; B. Lindkvist; M. Wittig; R.J. Porte; K. Holm; C. Gieger; H.E. Wichmann; P. Stokkers; C.Y. Ponsioen; H. Runz; A. Stiehl; C. Wijmenga; M. Sterneck; S. Vermeire; U. Beuers; A. Villunger; E. Schrumpf; K.N. Lazaridis; M.P. Manns; S. Schreiber; T.H. Karlsen

    2011-01-01

    Primary sclerosing cholangitis (PSC) is a chronic bile duct disease affecting 2.4-7.5% of individuals with inflammatory bowel disease. We performed a genome-wide association analysis of 2,466,182 SNPs in 715 individuals with PSC and 2,962 controls, followed by replication in 1,025 PSC cases and 2,17

  4. Recorrido de un artista plástico

    Directory of Open Access Journals (Sweden)

    Carlos Barreiro Ortiz

    2014-03-01

    Full Text Available Hiper/ultra/neo/post: Miguel Ángel Rojas, 30 años de arte en Colombia. Santiago Rueda. Instituto Distrital de Cultura y Turismo, Alcaldía Mayor de Bogotá, Bogotá, Colección de ensayos sobre el campo del arte, Ensayos de autor, 2005, 217 págs.

  5. AcEST: DK962549 [AcEST

    Lifescience Database Archive (English)

    Full Text Available YTS Sbjct: 80 QHRAGVSPYTS 90 >tr|Q1R3T7|Q1R3T7_ECOUT Putative uncharacterized protein OS=Escherichia coli (strain UTI89 / UPEC...S=Escherichia coli (strain UTI89 / UPEC) GN=UTI89_C3718 PE=4 SV=1 Length = 80 Score = 88.2 bits (217), Expec

  6. p21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner

    DEFF Research Database (Denmark)

    Wang, Zhipeng; Fu, Meng; Wang, Lifeng;

    2013-01-01

    PAK1 plays an important role in proliferation and tumorigenesis, at least partially by promoting Erk phosphorylation of c-Raf (Ser 338) or Mek1 (Ser 298). We observed now that overexpression of a kinase-dead mutant form of PAK1 increased phosphorylation of Mek1/2 (Ser 217/221) and Erk (Thr 202/Tyr...

  7. 38 CFR 3.103 - Procedural due process and appellate rights.

    Science.gov (United States)

    2010-07-01

    ... right of representation. Proceedings before VA are ex parte in nature, and it is the obligation of VA to... the decision, the right to a hearing on any issue involved in the claim, the right of representation... procedures set forth in § 3.217(b)), with knowledge or notice that such information would be used...

  8. Arts Education and Creativity Enhancement in Young Children in Hong Kong

    Science.gov (United States)

    Hui, Anna N. N.; He, Mavis W. J.; Ye, Shengquan Sam

    2015-01-01

    The present study aimed at assessing Hong Kong young children's gains in creativity and their teachers' application of arts education after a one-year artists-teachers collaborative arts education project that involves various art forms (i.e. drama, visual arts and integrated). Participants included 790 young children, 217 parents and 65 teachers…

  9. The Essential Elements of Successful Marriage and Family Therapy: A Modified Delphi Study.

    Science.gov (United States)

    White, Mark B.; Edwards, Scott A.; Russell, Candyce S.

    1997-01-01

    A panel of American Association of Marriage and Family Therapy approved supervisors generated 771 variables thought to be fundamental to positive marriage and family therapy (MFT) outcome, and rated 217 of these variables as very important to the successful outcome of MFT. The variables were collapsed into five categories and further condensed…

  10. 40 CFR Appendix G to Part 50 - Reference Method for the Determination of Lead in Suspended Particulate Matter Collected From...

    Science.gov (United States)

    2010-07-01

    ... the 217.0 nm line. Dual beam instruments with a continuum source give the most accurate correction. A... contamination and loss of sample. (16). 7.2 Sample preparation. 7.2.1 Hot extraction procedure. 7.2.1.1 Cut a 3... being used—has any bias. Quality control charts should be established to monitor differences...

  11. Securing tropical forest carbon: the contribution of protected areas to REDD

    DEFF Research Database (Denmark)

    Scharlemann, J.P.W.; Kapos, V.; Campbell, A.;

    2010-01-01

    Forest loss and degradation in the tropics contribute 6-17% of all greenhouse gas emissions. Protected areas cover 217.2 million ha (19.6%) of the world's humid tropical forests and contain c. 70.3 petagrams of carbon (Pg C) in biomass and soil to 1 m depth. Between 2000 and 2005, we estimate tha...

  12. Cessation of smoking after first-ever stroke: a follow-up study

    DEFF Research Database (Denmark)

    Bak, Søren; Sindrup, Søren Hein; Alslev, Torben;

    2002-01-01

    and at follow-up were included in the present study. Among 198 patients (38.7%) who were current smokers on admission, 43 patients (21.7%) gave up smoking within 6 months of suffering a stroke. Sex, functional status, and sociodemographic characteristics were independently associated with persistent smoking...

  13. 76 FR 7719 - Promoting Diversification of Ownership in the Broadcasting Services

    Science.gov (United States)

    2011-02-11

    ... adopted at 73 FR 28361, May 16, 2008, are effective on March 14, 2011. FOR FURTHER INFORMATION CONTACT... Docket Nos. 01-235, 01-317, 00-244; FCC 07-217, 73 FR 28361, May 16, 2008. Synopsis As required by the... hours and burden costs published in the Federal Register on October 13, 2010, 75 FR 62816 have...

  14. Help-Seeking Tendencies during Early Adolescence: An Examination of Motivational Correlates and Consequences for Achievement

    Science.gov (United States)

    Ryan, Allison M.; Shin, Huiyoung

    2011-01-01

    The present study examined the motivational correlates and achievement consequences of students' help-seeking tendencies during sixth grade (N = 217). Students' grades were collected from school records at the beginning and end of the school year. Midway through the year students reported on their academic self-efficacy and social demonstration…

  15. Clinical Implications of DSM-IV Subtyping of Bipolar Disorders in Referred Children and Adolescents

    Science.gov (United States)

    Masi, Gabriele; Perugi, Giulio; Millepiedi, Stefania; Mucci, Maria; Pari, Cinzia; Pfanner, Chiara; Berloffa, Stefano; Toni, Cristina

    2007-01-01

    Objective: According to DSM-IV, bipolar disorders (BDs) include four subtypes, BD I, BD II, cyclothymic disorder, and BD not otherwise specified (NOS). We explore the clinical implications of this subtyping in a naturalistic sample of referred youths with BD I, BD II, and BD-NOS. Method: The sample consisted of 217 patients, 135 males and 82…

  16. 36 CFR 251.83 - Decisions not appealable.

    Science.gov (United States)

    2010-07-01

    ... Freedom of Information Act denials under 7 CFR part 1 or Privacy Act determinations under 7 CFR 1.118. (c... only reviewable under 36 CFR part 217. (m) Decisions related to rehabilitation of National Forest... archaeological violations under 36 CFR 296.15 or for violations of prohibitions and orders under 36 CFR part...

  17. 75 FR 53565 - Adjustment of Appendices to the Dairy Tariff-Rate Import Quota Licensing Regulation for the 2010...

    Science.gov (United States)

    2010-09-01

    ... Origin Tokyo Round Uruguay Round NON-CHEESE ARTICLES BUTTER (NOTE 6) 5,217,229 1,759,771 EU-25 75,000 21...,500 PERCENT OF BUTTERFAT AND/OR BUTTER OIL (NOTE 14) Any Country 6,080,500 TOTAL: NON-CHEESE ARTICLES... Part 6 Agricultural commodities, Cheese, Dairy products, Imports, Reporting and...

  18. Some new generalizations of Hardy's integral inequalities

    International Nuclear Information System (INIS)

    In this paper, some new generalizations of Hardy's integral inequalities are obtained. These inequalities on the one hand generalize and on the other hand improve some existing results by Bicheng et al. [J. Math. Anal. Appl. 217(1998), 321-327]. (author)

  19. 77 FR 41481 - Integration of Variable Energy Resources

    Science.gov (United States)

    2012-07-13

    ... the purpose of power production forecasting. DATES: Effective Date: This rule will become effective... Energy Policy and Innovation, Federal Energy Regulatory Commission, 888 First Street NE., Washington, DC... Forecasting 1. Data Requirements 155 2. Definition of VER 200 3. Data Sharing 217 4. Cost Recovery 222...

  20. The Effect of Community College Enrollment on Bachelor's Degree Completion

    Science.gov (United States)

    Doyle, William R.

    2009-01-01

    Rouse [Rouse, C. E. (1995). "Democratization or diversion--the effect of community-colleges on educational-attainment." "Journal of Business and Economic Statistics, 13"(2), 217-224] finds that enrollment in a community college may divert students from attaining a bachelor's degree. However, this result may be due to selection…

  1. 30 Years,Open Wisely

    Institute of Scientific and Technical Information of China (English)

    Wang Ting

    2009-01-01

    @@ Over the 30 years,since the Reform and Opening-up, to the outside world, Chinese foreign trade has inreased from 20.6 billion USD in 1978 to 2.17 trilliion USD in 2007,up by 105 times, with an average annual growth of 17.4%.

  2. 75 FR 16068 - Opportunity for Designation in the Amarillo, TX; Cairo, IL; State of Louisiana; State of North...

    Science.gov (United States)

    2010-03-31

    ... this official agency: Armstrong (north of Prairie Dog Town Fork of the Red River), Carson, Childress...), Harley, Hemphill, Hutchinson, Lipscomb, Moore, Ochiltree, Oldham, Potter, Randall (north of Prairie Dog Town Fork of the Red River, State Route 217 and FM 1062), Roberts, Sherman, and Wheeler Counties...

  3. Time in U.S. Residency and the Social, Behavioral, and Emotional Adjustment of Latino Immigrant Families

    Science.gov (United States)

    Martinez, Charles R., Jr.; McClure, Heather H.; Eddy, J. Mark; Wilson, D. Molloy

    2011-01-01

    Little is known about contributors to positive social, behavioral, and emotional adjustment among foreign-born youth at different stages of adapting to life in the United States. Using baseline data from the Adolescent Latino Acculturation Study (N = 217), this article examines the effects of time in residency on parent adjustment, family stress,…

  4. Geochemical modeling of water-gas-rock interactions. Application to mineral diagenesis in geologic reservoirs; Modelisation geochimique des interactions eau-gaz-roche. Application a la diagenese minerale dans les reservoirs geologiques

    Energy Technology Data Exchange (ETDEWEB)

    Bildstein, O.

    1998-03-13

    The Ph.D. report describes a conceptual and numerical model for simulating gas-water-rock interaction during mineral diagenesis of sediments. The main specific features of this model are the following: applicable to open systems, half-implicit resolution numerical method, feedback on the texture evolution (grain model), existence of a gas phase, oxido-reduction phenomena. (author) 217 refs.

  5. Review: From disgust to humanity--sexual orientation and constitutional law

    Directory of Open Access Journals (Sweden)

    Alba Izado Leon Hernandez

    2011-05-01

    Full Text Available

    REVIEW

    FROM DISGUST TO HUMANITY: SEXUAL ORIENTATION AND CONSTITUTIONAL LAW

    Martha C. Nussbaum
    Oxford University Press 2010
    217 pages,
    ISBN-13: 978-0-19-530531-9

  6. Gas dynamic lasers (a bibliograpy with abstracts). Report for 1964-aug 77

    Energy Technology Data Exchange (ETDEWEB)

    Smith, M.F.

    1977-09-01

    The citations cover research on kinetic and energy transfer processes, design, optics, nozzles, and performance of gas and chemical lasers relying on gas dynamic effects for lasing enhancement. Diffusion and flow studies specifically applicable to such lasers are also included. (This updated bibliography contains 217 abstracts, 43 of which are new entries to the previous edition.)

  7. Questions

    DEFF Research Database (Denmark)

    Larsen, Steen Nepper

    2012-01-01

    Bidrag til festskrift til Jesper Hoffmeyer i anledning af hans 70 års dag i Don Favineau, Paul Cobley & Kalevi Kull (eds.): "A More Developed Sign. Interpreting the Work of Jesper Hoffmeyer". Antologien udg. som særnummer af Tartu Semiotics Library Nr. 10 og mit bidrag forefindes på p. 217-220....

  8. 76 FR 11411 - Defense Federal Acquisition Regulation Supplement; Multiyear Contracting (DFARS Case 2009-D026)

    Science.gov (United States)

    2011-03-02

    ... aircrew members or foreign language training); (4) Base services (e.g., ground maintenance, in-plane... Defense Acquisition Regulations System 48 CFR Part 217 RIN 0750-AG89 Defense Federal Acquisition Regulation Supplement; Multiyear Contracting (DFARS Case 2009-D026) AGENCY: Defense Acquisition...

  9. 75 FR 28245 - Massachusetts Marine Sanitation Device Standard-Receipt of Petition

    Science.gov (United States)

    2010-05-20

    ... Administrator, U.S. Environmental Protection Agency, that adequate facilities for the safe and sanitary removal...-217 and Public Law 100-4, that adequate facilities for the safe and sanitary removal and treatment of...-2812 VHF Mon-Fri 8am-6pm; 4 ft. 9, 16. Sat--Sun 8am-5pm. Newbury Riverfront Marina....... 292 High...

  10. 77 FR 35879 - Defense Federal Acquisition Regulation Supplement: Title 41 Positive Law Codification-Further...

    Science.gov (United States)

    2012-06-15

    ... Defense Acquisition Regulations System 48 CFR Parts 201, 203, 204, 212, 213, 217, 219, 222, 225, 233, 243, 252, and Appendix I to Chapter 2 RIN 0750-AH55 Defense Federal Acquisition Regulation Supplement: Title 41 Positive Law Codification--Further Implementation (DFARS Case 2012- D003) AGENCY:...

  11. Beginning Teachers' Perceptions of Mentoring, Climate, and Leadership: Promoting Retention through a Learning Communities Perspective

    Science.gov (United States)

    Wynn, Susan R.; Carboni, Lisa Wilson; Patall, Erika A.

    2007-01-01

    Often viewed as a recruitment issue, the teacher shortage is better defined as a retention issue. This three-year study examines teacher retention through a professional learning communities framework. During the first year of data collection, 217 first- and second-year teachers in a small urban school district were surveyed to assess their…

  12. The Contribution of Personality Traits, Motivation, Academic Risk-Taking and Metacognition to the Creative Ability in Mathematics

    Science.gov (United States)

    Erbas, Ayhan Kursat; Bas, Selda

    2015-01-01

    The purpose of this study was to investigate the extent to which personality traits, motivation, academic risk-taking, and metacognition explain the mathematical creative ability of high school students. The participants were 217 9th-grade students that were exceptionally high achievers. The participants responded to a set of measures about…

  13. Interrater Reliability of the 6-Minute Walk Test in Women With Hip Fracture

    DEFF Research Database (Denmark)

    Larsen, Camilla Marie; Overgaard, Jan; Holtze, Steffen;

    2016-01-01

    of 3.2 [31.5] m, P = .83) between the 2 raters, and no heteroscedasticity was observed ( r = −0.196, P = .41). By contrast, participants walked an average of 21.7 (22.5) m longer during the second trial ( P = .002). Participants with moderate hip fracture-related pain walked a shorter distance than...

  14. North Carolina Infant, Toddler & Preschooler Assistive Technology Needs Assessment. A Report on the Provision of Assistive Technology Devices and Services to Children with Disabilities from Birth to Age 5 in North Carolina.

    Science.gov (United States)

    Trachtman, Lawrence H.; Pierce, Patsy L.

    A survey of assistive technology use among North Carolina children with disabilities age 5 and under is reported and illustrated with graphs and charts. Responses from 160 agencies provided information on 2,217 children currently receiving or requiring assistive devices and services. Results are summarized in terms of demographic findings, costs…

  15. Birth Defects in Newborns: Spina Bifida Index at Rio Grande Do Norte State in Brazil

    Directory of Open Access Journals (Sweden)

    Arnaldo CM Junior

    2014-08-01

    Conclusion: Northeast region is the one that has the major incidence of SB in Brazil country, but RN state has a number lower than others states from its region. It was made an update about therapeutic options to minimize the morbidity and mortality in newborn with SB congenital defects. [J Interdiscipl Histopathol 2014; 2(4.000: 217-223

  16. Environmental impact of Hurricane Katrina on Lake Pontchartrain: Chapter 7G in Science and the storms-the USGS response to the hurricanes of 2005

    Science.gov (United States)

    Heitmuller, Thomas; Perez, Brian C.

    2007-01-01

    Hurricane Katrina slammed the Louisiana-Mississippi Gulf Coast with 135-mi/hour (217-km/hour) winds and up to a 30-ft (9-m) storm surge. Lake Pontchartrain was further subjected to environmental threat by way of the millions of gallons of contaminated flood water that were pumped daily from the city of New Orleans into the lake.

  17. An Investment Opportunity China's Pharmaceutical Industry: TIANJIN JINHUI PHARMACEUTICAL CO, LTD

    Institute of Scientific and Technical Information of China (English)

    Xianping; Liu

    2007-01-01

    @@ People say, pharmaceutical is an eternal industry "facing the Sun" in the world market. In 1970, the total revenue pharmaceutical industry was only ($)2.17 Billion, which was raised greatly to ($)41.10 Billion in 2002 and increased further by 7% annually, reaching ($)500 Billion in 2005.

  18. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    DEFF Research Database (Denmark)

    Taylor, Jenny C; Martin, Hilary C; Lise, Stefano;

    2015-01-01

    To assess factors influencing the success of whole-genome sequencing for mainstream clinical diagnosis, we sequenced 217 individuals from 156 independent cases or families across a broad spectrum of disorders in whom previous screening had identified no pathogenic variants. We quantified the numb...

  19. Bad Luck or Bad Decisions: College Students' Perceptions of the Reasons for and Consequences of Their Alcohol Overdose

    Science.gov (United States)

    Reis, Janet

    2007-01-01

    Reasons for and immediate consequences of an alcohol overdose were explored for 217 undergraduate students requiring a medical emergency transport because of excessive alcohol consumption. The sample was categorized into 26 students attributing their overdose solely to bad luck and 191 students citing bad decision making as an explanation. A…

  20. Complete Genome Sequence of Bovine Viral Diarrhea Virus-1 Strain Egy/Ismailia/2014, Subtype 1b

    OpenAIRE

    Soltan, Mohamed A.; Wilkes, Rebecca P.; Elsheery, Mohamed N.; Elhaig, Mahmoud M.; Riley, Matthew C.; Melissa A. Kennedy

    2015-01-01

    Here, we report the complete genome sequence of bovine viral diarrhea virus-1b (BVDV-1b), strain Egy/Ismailia/2014. The virus genome is composed of 12,217 nucleotides organized as one open reading frame encoding 3,898 amino acids. This report will assist efforts in diagnostics, studying molecular epidemiology, and control of BVDV in Egypt.